LOCUS       DAVBBO010000001        83347 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ST1
            SAMEA2066453-rid20184263.denovo.001, whole genome shotgun sequence.
ACCESSION   DAVBBO010000001 DAVBBO010000000
VERSION     DAVBBO010000001.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2066453
            Sequence Read Archive: ERR351777
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 83347)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 83347)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980402.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980402.1
            Genome Coverage       :: 176x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:17:33
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,141
            CDSs (total)                      :: 2,104
            Genes (coding)                    :: 1,953
            CDSs (with protein)               :: 1,953
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 16S)
            partial rRNAs                     :: 1 (23S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 151
            CDSs (without protein)            :: 151
            Pseudo Genes (ambiguous residues) :: 0 of 151
            Pseudo Genes (frameshifted)       :: 73 of 151
            Pseudo Genes (incomplete)         :: 76 of 151
            Pseudo Genes (internal stop)      :: 40 of 151
            Pseudo Genes (multiple problems)  :: 32 of 151
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..83347
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2066453-rid20184263.denovo.001"
                     /strain="ST1"
                     /db_xref="taxon:1313"
     gene            <1..174
                     /locus_tag="VQU30_000001"
     CDS             <1..174
                     /locus_tag="VQU30_000001"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HET2446202.1"
                     /translation="EDKAYNHALSKERSKVENIFAKVKTFKMFSTTYRNHRKRFGLRM
                     NLIAGIINHELGF"
     gene            242..490
                     /locus_tag="VQU30_000002"
     CDS             242..490
                     /locus_tag="VQU30_000002"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001858369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2446203.1"
                     /translation="MVSSSGSEFQSGWQEHQLIAEKVSKTLDKTFDKDVREIPTSQFY
                     QKFVDEMGRIYSGNLILQELITVNGAYKATYIGELSSN"
     gene            621..1793
                     /locus_tag="VQU30_000003"
     CDS             621..1793
                     /locus_tag="VQU30_000003"
                     /EC_number="2.3.3.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004181031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxymethylglutaryl-CoA synthase"
                     /protein_id="HET2446204.1"
                     /translation="MTIGIDKIGFATSQYVLKLQDLAEARGIDPEKLSKGLLLKELSI
                     APLTEDIVTLAASASDSILTEQERQEVDMVIVATESGIDQSKAAAVFVHGLLGIQPFA
                     RSFEIKEACYGATAALHYAKLHVENSPESKVLVIASDIAKYGIETPGEPTQGAGSVAM
                     LITQNPRMMAFNNDNVAQTRDIMDFWRPNYSTTPYVNGVYSTQQYLDSLKTTWLEYQK
                     RYQLTLDDFAAVCFHLPYPKLALKGLKKIMDKSLPQEKKDLLQKHFDQSILYSQKVGN
                     IYTGSLFLGLLSLLENADSLKAGDKIALYSYGSGAVAEFFSGELVEGYEAYLDKDRLN
                     KLNQRTALSVADYEKVFFEEVNLDETNSAQFAGYENQDFALVEILDHQRRYSKVEK"
     gene            1793..3067
                     /locus_tag="VQU30_000004"
     CDS             1793..3067
                     /locus_tag="VQU30_000004"
                     /EC_number="1.1.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000704367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxymethylglutaryl-CoA reductase,
                     degradative"
                     /protein_id="HET2446205.1"
                     /translation="MKISWNGFSKKSYQERLELLKAQALLSPERQASLEKDEQMSVTV
                     ADQLSENVVGTFSLPYSLVPEVLVNGQEYTVPYVTEEPSVVAAASYASKIIKRAGGFT
                     AQVHQRQMIGQVALYQVANPKLAQEKIASKKAELLEFANQAYPSIVKRGGGARDLHVE
                     QIKGEPDFLVVYIHVDTQEAMGANMLNTMLEALKPVLEELSQGQSLIGILSNYATDSL
                     VTASCRMAFRYLSRQKDQGREIAEKIALASQFAQADPYRAATHNKGIFNGIDAILIAT
                     GNDWRAIEAGAHAFASRDGRYQGLSCWTLDLEREELVGEMTLPMPVATKGGSIGLNPR
                     VAFSHDLLGNPSARELAQIIVSIGLAQNFAALKALVSTGIQQGHMKLQAKSLALLAGA
                     SESEVAPLVERLISDKTFNLETAQRYLENLRS"
     gene            complement(3103..4068)
                     /locus_tag="VQU30_000005"
     CDS             complement(3103..4068)
                     /locus_tag="VQU30_000005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002929307.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HET2446206.1"
                     /translation="MVAKLTDVAKLAGVSPTTVSRVINKKGYLSEKTIQKVNEAMREL
                     GYKPNNLARSLQGKSAKLIGLIFPNISNVFYAELIDKLEHQLFKNGYKTIICNSEHDS
                     EKEREYIEMLEANQVDGIISGSHNLGIEDYNRVTAPIISFDRNLSPDIPVVSSDNYAG
                     GVLAAQTLVKTGAQTIIMITGNDNSNSPTGLRHAGFASVLPKAPIINVSSDFSPVRKE
                     MEIKNILTREKPDAIFASDDLTAILVIKIAQELGISVPKELKVIGYDGTYFIENYYPQ
                     LATIKQPLEEIACLTIDLLLQKIEGKEVATTGYFLPVTLLPGKSI"
     gene            complement(4049..5503)
                     /locus_tag="VQU30_000006"
     CDS             complement(4049..5503)
                     /locus_tag="VQU30_000006"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000455313.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 32 protein"
                     /protein_id="HET2446207.1"
                     /translation="MEWTTERRYRLYQDWTQEEIQHIKENMAQSPWHTHYHVEPKTGL
                     LNDPNGFSYFDGKWILFYQNFPFGAAHGLKSWAQLESDDLVHFKETGIKVLPDTPLDS
                     HGAYSGSAMQFGDNLFLFYTGNVRDENWIRHPYQIGALMDKEGKITKIDKILIDQPAD
                     STDHFRDPQIFNFKSQYYAVVGGQDLEKKGFVRLYKAVNNDYTNWQAVGDLDFANDRT
                     AYMMECPNLVFVEEHPVLLYCPQGLDKKVLDYDNIFPNMYKIGASFDPKNAKMVDVSQ
                     LQNMDYGFEAYATQAFNAPDGRALAVSWLGLPDVSYPSDRFDHQGTFSLVKELTIKDD
                     KLYQYPVAAIKDLRASEEAFSNRSQTKNTYELELNLEANSQSEIVLLADKEGKGLSIN
                     FDLVNGQVTVDRSQAGEQYAQEFGTTRSCPIENQATTATIFIDNSVFEIFINKGEKVF
                     SGRVFPHADQNGILIKSGNPTGTYYELDYGRKTN"
     gene            5880..7763
                     /locus_tag="VQU30_000007"
     CDS             5880..7763
                     /locus_tag="VQU30_000007"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864794.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HET2446208.1"
                     /translation="MNNQEIAKKVIDALGGRENVNSVAHCATRLRVMVKDEEKINKEV
                     IENLEKVQGAFFNSGQYQIIFGTGTVNKMYDEVVVLGLPTSSKDDMKAEVAKQGNWFQ
                     RAIRTFGDVFVPIIPVIVATGLFMGVRGLFNALEMPLPGDFATYTQILTDTAFIILPG
                     LVVWSTFRVFGGNPAVGIVLGMMLVSGSLPNAWAVAQGGEVTAMNFFGFIPVVGLQGS
                     VLPAFIIGVVGAKFEKAVRKVVPDVIDLLVTPFVTLLVMSILGLFVIGPVFHVVENYI
                     LIATKAILSMPFGLGGFLIGGVHQLIVVSGVHHIFNLLEVQLLAADHANPFNAIITAA
                     MTAQGAATVAVGVKTKNPKLKTLAFPAALSAFLGITEPAIFGVNLRFRKPFFLSLIAG
                     AIGGGLASILGLAGTGNGITIIPGTMLYVGNGQLPQYLLMVAVSFALGFALTYMFGYE
                     DEVDATAAAKQAEVAEEKEEVAPAALQNETLVTPIVGDVVALADVNDPVFSSGAMGQG
                     IAVKPSQGVVYALADAEVSIAFPTGHAFGLKTRNGAEVLIHVGIDTVSMNGDGFEAKV
                     AQGNKVKAGDVLGTFDSNKIAAAGLDDTTMVIVTNTADYASVAPVATGSVSKGDAVIE
                     VKI"
     gene            7912..8799
                     /locus_tag="VQU30_000008"
     CDS             7912..8799
                     /locus_tag="VQU30_000008"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000164317.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HET2446209.1"
                     /translation="MTKLYGSLEAGGTKFVCAVGDENFNVVEKTQFPTTTPIETIDKT
                     IEFFSKFDNLAGLAVGSFGPIDIDKNSKTYGFITTTPKPNWANVDLLGALRRALNVPM
                     YFTTDVNSSAYGEMVARNNAGGRIENLVYYTIGTGIGAGVIQRGEFIGGVGHPEMGHY
                     YVARHPMDIEKEFKGVCPFHKGCLEGYAAGTSLEARTGVRGETIELNNPVWDVQAYYI
                     AQAAVNATVTFRPDVIVFGGGVMAQQHMLDRVREKFTSLLNGYLPVPDVRDYIVTPAV
                     AGNGSATLGNFVLAKEVSK"
     gene            complement(9119..9736)
                     /locus_tag="VQU30_000009"
     CDS             complement(9119..9736)
                     /locus_tag="VQU30_000009"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000076166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TVP38/TMEM64 family protein"
                     /protein_id="HET2446210.1"
                     /translation="MSQDKQMKAVSPLLQRVINISSIVGGVGSLIFCIWAYQAGILQS
                     KETLSAFIQQAGIWGPPLFIFLQILQTVVPIIPGALTSVAGVFIYGHIIGTIYNYIGI
                     VIGCAIIFYLVRLYGAAFVQSVVSKRTYDKYIGWLDKGNRFDRFFIFMMIWPISPADF
                     LCMLAALTKMSFKRYMTIIILTKPFTLVVYTYGLTYIIDFFWQML"
     gene            complement(10151..10339)
                     /locus_tag="VQU30_000010"
                     /pseudo
     CDS             complement(10151..10339)
                     /locus_tag="VQU30_000010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001153868.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
     gene            complement(10849..10929)
                     /locus_tag="VQU30_000011"
                     /pseudo
     CDS             complement(10849..10929)
                     /locus_tag="VQU30_000011"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820552.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopyranose mutase"
     gene            11045..11938
                     /locus_tag="VQU30_000012"
     CDS             11045..11938
                     /locus_tag="VQU30_000012"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000895295.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET2446211.1"
                     /translation="MLEVRSLEKSFGSKQVLFGIDFQARPGRILGLVGKNGAGKTTIF
                     HSILKFLEYQGEIGLDGQDIRQETYARIGYLPEERSLMPKLTVLEQVRYLATLKGMDA
                     KEVKEKLPQWMKRLEVKGKLTDKIKSLSKGNQQKIQLIITLIHEPDLIILDEPFSGLD
                     PVNTELLKQVIFQEKERGATIIFSDHVMTNVEELCDDILMIRDGRVVLHGPVQDVRNQ
                     YGKTRLFVSSERSKEELENLPHVKQVSLTKQGSWKLILEDESAGRELFPILTQGQYIA
                     TFDQQAPTIDEIFKLESGVEV"
     gene            11935..13134
                     /locus_tag="VQU30_000013"
     CDS             11935..13134
                     /locus_tag="VQU30_000013"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001245382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HET2446212.1"
                     /translation="MRNMWVVIKETYLRHVESWSFFFMVISPFLFLGISVGIGHLQGS
                     SMAKNNKVAVVTTVPSVAEGLKNVNGVNFDYKDEASAKEAIKEEKLKGYLTIDQEDSV
                     LKAVYHGETSLENGIKFEVTGTLNELQNQLNRSTASLSQEQEKRLEQTIQFTEKIDEA
                     KENKKFIQTIAAGALGFFLYMILITYAGVTAQEVASEKGTKIMEVVFSSIRASHYFYA
                     RMMALFLVILTHIGIYVVGGLAAVLLFKDLPFLAQSGILDHLGDAISLNTLLFILISL
                     FMYVVLAAFLGSMVSRPEDSGKALSPLMILIMGGFFGVTALGAAGDNLLLKIGSYIPF
                     ISTFFMPFRTINGYAGGAEAWISLAITVIFAVVATGFIGRMYASLVLQTDDLGIWKTF
                     KRALSYK"
     gene            complement(13487..14254)
                     /locus_tag="VQU30_000014"
     CDS             complement(13487..14254)
                     /locus_tag="VQU30_000014"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000498762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2446213.1"
                     /translation="MFWNLVHYEFKNVNKWYLALYAAVLVLSALIGIQTQGFKNLPYQ
                     ESQATMLLFLATVFGGLMLTLAISTIFLIIKRFKGSVYDRQGYLTLTLPVSEHHIITA
                     KLIGAFIWSLISTAVLALSAVIILALTAPEWIPLSYVITFVETHLPQIFLTGISFLLN
                     TISGILCIYLAISIGQLFNEYRTALAVAAYIGIQIVIGFIELFFNLSSNFYVNSLVGL
                     NDHFYMGAGIAIVKELIFIAIFYLGTYYILRNKVNLL"
     gene            complement(14271..14966)
                     /locus_tag="VQU30_000015"
     CDS             complement(14271..14966)
                     /locus_tag="VQU30_000015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004256110.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET2446214.1"
                     /translation="MSLLVFENVSKSYGATPALENVSLDIPAGKIVGLLGPNGSGKTT
                     LIKLINGLLQPDQGRVLINDMDPSPATKAVVAYLPDTTYLNEQMKVKEALTYFKTFYK
                     DFNLERAHHLLADLGIDENSRLKKLSKGNKEKVQLILVMSRDARLYVLDEPIGGVDPA
                     ARAYILNTIINNYSPTSTVLISTHLISDIEPILDEIVFLKDGKVVRQGNVDDIRYESG
                     ESIDQLFRQEFKA"
     gene            complement(14971..15336)
                     /locus_tag="VQU30_000016"
     CDS             complement(14971..15336)
                     /locus_tag="VQU30_000016"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004256112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HET2446215.1"
                     /translation="MSWTFDNKKPIYLQIMEKIKLQIVSHTLEPNQQLPTVRELASEA
                     GVNPNTIQRALSDLEREGFVYSKRTTGRFVTKDKELIAQSRKQLSEEELEHFVSSMIH
                     FGYEKEELPGVVSDYIKGV"
     gene            15476..15949
                     /gene="nrdR"
                     /locus_tag="VQU30_000017"
     CDS             15476..15949
                     /gene="nrdR"
                     /locus_tag="VQU30_000017"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001203675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional repressor NrdR"
                     /protein_id="HET2446216.1"
                     /translation="MRCPKCGATKSSVIDSRQAEEGNTIRRRRECDECQHRFTTYERV
                     EERTLVVVKKDGTREQFSRDKIFNGIIRSAQKRPVSSDEINMVVNRIEQKLRGRNENE
                     IQSEDIGSLVMEELAELDEITYVRFASVYRSFKDVSELESLLQQITQSSKKKKER"
     gene            15950..17119
                     /locus_tag="VQU30_000018"
     CDS             15950..17119
                     /locus_tag="VQU30_000018"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000802368.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation and membrane attachment
                     family protein"
                     /protein_id="HET2446217.1"
                     /translation="MKPIDRFSYLKNNRVSQDTSSLVQCYLPIIGQEALSLYLYTISF
                     WDNGRKEYLFSSILNHLNFGMDRLIKSLKILSAFNLLTLYQKGDVYQLALHAPLSSQD
                     FLEHPVYRRLLEKKIGDSAVEDLKVESADGEEIPVSLNQVFPELAELGSQEDLGLKKK
                     VANDFDLEHFRQLMARDGLRFADEQSDVLNLFAIAEEKKWTWFETYQLAKSTAVSQVI
                     STKRMREKIAQKPVSSDFNPKEATIIKEAKSKTALQFLAEIKQTRKGTITQTERELLQ
                     QMAGLGLLDEVINIILLLTFNKVDSANINEKYAMKVANDYAYQKIHSAEEAVLRIRER
                     GQKTKTQKQNQTAPAKTNIPKWSNPDYKNETSEETRLELERKKQELLARLEKGGD"
     gene            17120..18016
                     /gene="dnaI"
                     /locus_tag="VQU30_000019"
     CDS             17120..18016
                     /gene="dnaI"
                     /locus_tag="VQU30_000019"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398880.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="primosomal protein DnaI"
                     /protein_id="HET2446218.1"
                     /translation="MESVGDVLKRQPSRFYYQDLVQKIMKDPDVAAFIQQESLTPEEL
                     NRSISKFNQYITERDKFLRGDTDYIAKGYKPILVKNHGYADVSYEETPELIAAEKEAA
                     IKNRLKLINLPASLKKASLAQVDLDDLGRLPVFEKLLAFVEQYPAIRKGLYLYGDFGV
                     GKSFMVAALAHDLSEKRGVSSTLLHYPSFVIDVKNAISDGNVKTLVDEIKLSEVLILD
                     DIGAEQSTAWVRDEILQVILQYRMQENLPTFFTSNFNFEDLEKHFAKVKHGNDETWEA
                     RRVMERIRYLAEETRLEGVNRR"
     gene            18013..18726
                     /locus_tag="VQU30_000020"
     CDS             18013..18726
                     /locus_tag="VQU30_000020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000140867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADPH-dependent oxidoreductase"
                     /protein_id="HET2446219.1"
                     /translation="MTETIKLMKAHTSVRRFKEQEIPQVDLNEILTAAQMASSWKNFQ
                     SYSVIVVRSQEKKDALYELVPQEAIRQSAVFLLFVGDLNRAEKGARLHTDTFQPQGVE
                     GLLISSVDAALAGQNALLAAESLGYGGVIIGLVRYKSEEVAELFNLPDYTYSVFGMAL
                     GVPNQHHDMKPRLPLENVVFEEEYQEQSTEAIQAYDRVQADYAGARATTSWSQRLAEQ
                     FGQAEPSSTRKNLEQKKLL"
     gene            18740..20050
                     /gene="der"
                     /locus_tag="VQU30_000021"
     CDS             18740..20050
                     /gene="der"
                     /locus_tag="VQU30_000021"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018377046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTPase Der"
                     /protein_id="HET2446220.1"
                     /translation="MALPTIAIVGRPNVGKSTLFNRIAGERISIVEDVEGVTRDRIYA
                     TGEWLNRSFSMIDTGGIDDVDAPFMEQIKHQAEIAMEEADVIVFVVSGKEGITDADEY
                     VARKLYKTHKPVILAVNKVDNPEMRNDIYDFYALGLGEPLPISSVHGIGTGDVLDAIV
                     ENLPNEYEEENPDVIKFSLIGRPNVGKSSLINAILGEDRVIASPVAGTTRDAIDTHFT
                     DTDGQEFTMIDTAGMRKSGKVYENTEKYSVMRAMRAIDRSDVVLMVINAEEGIREYDK
                     RIAGFAHEAGKGMIIVVNKWDTLEKDNHTMKNWEEDIREQFQYLPYAPIIFVSALTKQ
                     RLHKLPEMIKQISESQNTRIPSAVLNDVIMDAIAINPTPTDKGKRLKIFYATQVATKP
                     PTFVIFVNEEELMHFSYLRFLENQIRKAFVFEGTPIHLIARKRK"
     gene            20141..20476
                     /locus_tag="VQU30_000022"
     CDS             20141..20476
                     /locus_tag="VQU30_000022"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000400494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2446221.1"
                     /translation="MEHLFKFLLLAPYFYFDNWIEKANRNSKFFPIFYYFYWFYIPFY
                     SLFSLAWTVVSVLFFNTVLRNVTDIKLWGIWFLFILLAIGMNWLTYSCFKEMFRLRQE
                     LGKSKGGRH"
     gene            20616..20951
                     /locus_tag="VQU30_000023"
     CDS             20616..20951
                     /locus_tag="VQU30_000023"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000400498.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2446222.1"
                     /translation="MEYLFKMIILLPCFYFFSWIEKANRDSKIFPIFYYFYWIYITLY
                     ALFSLAWTVFSVLFFNIVLRNLTDIKLWGIWLLLLLIAFASDWLDYICFKKMLDLRRE
                     LGKSKGGRH"
     gene            21136..21927
                     /locus_tag="VQU30_000024"
     CDS             21136..21927
                     /locus_tag="VQU30_000024"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398883.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2446223.1"
                     /translation="MKIPLLTLARHKFVYVLLTLLFLALVYRDVLMTYFFFDIHAPDL
                     AKFDGQAIKNDLLKSALDFRILQFNLGFYQSFIIPIIIVLLGFQYIELKNKVLRLSIG
                     REVSYQGLKRKLTLQVASIPCLIYLVTVLIIAIITYFFGTFSPLEWNSLFSDGSGLQR
                     LLDGEIKSYLFFTCVLLIGIFINAIYFLQIVDYVGNVTRSAITYLMFLWLGSMLLYSA
                     LPYYMVPMTSLMQASYGDVSLMKLFTPYILYVVPYMVLKKYEDNV"
     gene            21920..22561
                     /locus_tag="VQU30_000025"
     CDS             21920..22561
                     /locus_tag="VQU30_000025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000475766.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2446224.1"
                     /translation="MFKNFNNIWLKRKIVLLLRIVLMMILINYLLSTAVQKQDAVIFF
                     KRELISIFSYNDYSEANLEIPKLLLNLSLFMVGWLSVILLESDLADHYHHLIRYQSSS
                     FFDYTRKRLVVISKFFTQDLFVWFLGLLPLGIHFKTVALFFLLAQLMMLYLLLSYLIA
                     LISAGAGFSFFLYFLAFVGQEWMMDHIVTVYLVLLSLLVMLIVSRLEEKFKKG"
     gene            22565..23215
                     /locus_tag="VQU30_000026"
     CDS             22565..23215
                     /locus_tag="VQU30_000026"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000763094.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HET2446225.1"
                     /translation="MRLEIINGQKIYGKRPILNQLNLVFQSGKIYGLKGDNGSGKTVL
                     LKILAGYIKLDKGKVLQDGKVYGVKNHYIQDAGILIEKVEFLSHLSLRENLELLRYFS
                     SKVTEKRIAYWIQYYDLQEFEDVEYRHLSLGTKQKMALIQAFISSPSILFLDEPMNAL
                     DEKSVRLTKQVILSYLKKENGLVILTSHISEDISDLCTDVLVVENGHIQYVKDIQS"
     gene            23226..23513
                     /locus_tag="VQU30_000027"
     CDS             23226..23513
                     /locus_tag="VQU30_000027"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000940707.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2446226.1"
                     /translation="MAHLKSFITRYSKVYIGLVLLIWLSFFFIPWDRAILGVRIDIFI
                     MQKILLAFGILSILMALLSKKVSLFVFGLICCLSLWINLFITFAILPIFGN"
     gene            23659..26172
                     /gene="secA"
                     /locus_tag="VQU30_000028"
     CDS             23659..26172
                     /gene="secA"
                     /locus_tag="VQU30_000028"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398886.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecA"
                     /protein_id="HET2446227.1"
                     /translation="MANILKTIIENDKGEIRRLEKMADKVFKYEDQMATLTDDQLKAK
                     TVEFKERYQNGESLDSLLYEAFAVVREGAKRVLGLFPYKVQVMGGIVLHHGDVPEMRT
                     GEGKTLTATMPVYLNALSGKGVHVVTVNEYLSERDATEMGELYSWLGLSVGINLATKS
                     PMEKKEAYECDITYSTNSEIGFDYLRDNMVVRAENMVQRPLNYALVDEVDSILIDEAR
                     TPLIVSGANAVETSQLYHMADHYVKSLNKDDYIIDVQSKTIGLSDSGIDRAESYFKLE
                     NLYDIENVALTHFIDNALRANYIMLLDIDYVVSEEQEILIVDQFTGRTMEGRRYSDGL
                     HQAIEAKEGVPIQDETKTSASITYQNLFRMYKKLSGMTGTGKTEEEEFREIYNIRVIP
                     IPTNRPVQRIDHSDLLYASIESKFKAVVEDVKARYQKGQPVLVGTVAVETSDYISKKL
                     VAAGVPHEVLNAKNHYREAQIIMNAGQRGAVTIATNMAGRGTDIKLGEGVRELGGLCV
                     IGTERHESRRIDNQLRGRSGRQGDPGESQFYLSLEDDLMKRFGSERLKGIFERLNMSE
                     EAIESRMLTRQVEAAQKRVEGNNYDTRKQVLQYDDVMREQREIIYAQRYDVITADRDL
                     APEIQAMIKRTIERVVDGHARAKQDEKLEAILNFAKYNLLPEDSITMEDLSGLSDKAI
                     KEELFQRALKVYDSQVSKLRDEEAVKEFQKVLILRVVDNKWTDHIDALDQLRNAVGLR
                     GYAQNNPVVEYQAEGFRMFNDMIGSIEFDVTRLMMKAQIHEQERPQAERHISTTATRN
                     IAAHQASMPEDLDLSQIGRNELCPCGSGKKFKNCHGKRQ"
     gene            26253..27284
                     /locus_tag="VQU30_000029"
     CDS             26253..27284
                     /locus_tag="VQU30_000029"
                     /EC_number="2.5.1.54"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000232189.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-deoxy-7-phosphoheptulonate synthase"
                     /protein_id="HET2446228.1"
                     /translation="MVFTAKSSKINIEEVRALSKLEGQALERKSQRDQELEAIIRGED
                     QRILLVIGPCSSDNEEAVLEYAKRLAVLQEEVADRIFMVMRVYTAKPRTNGDGYKGLI
                     HQPNATEAPSLINGIKAVRHLHYRVITETGMTTADEMLYPENLPLVDDLISYMAVGAR
                     SVEDQQHRFVASGAGFSTGFKNPTSGNLNVMFNGIYAAQNKQSFLFLGKEVETTGNPL
                     SHAILRGALNEYGKNIPNYYYDNLIDTIAQYEKMGLENPFIIIDTNHDNSGKQYIEQI
                     RIVRQTLINRAWNEKIKQFVRGFMIESYLEDGRQNEPEVFGKSITDPCLGWDNTEALV
                     REIYKTLGE"
     gene            27286..28317
                     /locus_tag="VQU30_000030"
     CDS             27286..28317
                     /locus_tag="VQU30_000030"
                     /EC_number="2.5.1.54"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517149.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-deoxy-7-phosphoheptulonate synthase"
                     /protein_id="HET2446229.1"
                     /translation="MAFIEKGQEIDMEVIKAETQLSAEALRLKESRDRELADIISGED
                     DRILLVIGPCSSDNEEAVLEYARRLSALQKKVADKIFMVMRVYTAKPRTNGDGYKGLV
                     HQPDTSKAPSLINGLQAVRQLHYRVITETGLTTADEMLYPSNLILVDDLVSYHAVGAR
                     SVEDQEHRFVASGIDAPVGMKNPTSGNLGVMFNAIYAAQNKQTFLYHGQEVETSGNPL
                     AHVILRGAVNEYGNYMPNYYYENLLQAIERYETMGLENPFILIDTNHDNSGKQYMEQI
                     RIVRQTLQNRDWNEKIKKTVRGFMIESYLADGRQNQPEIFGCSITDPCLGWENTEALV
                     EEIYVTLTK"
     gene            28356..28724
                     /locus_tag="VQU30_000031"
     CDS             28356..28724
                     /locus_tag="VQU30_000031"
                     /EC_number="2.7.8.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000061844.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="holo-ACP synthase"
                     /protein_id="HET2446230.1"
                     /translation="MRMIVGHGIDIEELASIESAVTRHEGFAKRVLTAQEMERFTSLK
                     GRRQIEYLAGRWSAKEAFSKAMGTGISKLGFQDLEVLNNERGAPYFSQAPFSGKIWLS
                     ISHTDQFVTASVILEENHES"
     gene            28714..29817
                     /locus_tag="VQU30_000032"
     CDS             28714..29817
                     /locus_tag="VQU30_000032"
                     /EC_number="5.1.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000648075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alanine racemase"
                     /protein_id="HET2446231.1"
                     /translation="MKASPHRPTKALIHLGAIRQNIQQMGAHIPQGTLKLAVVKANAY
                     GHGAVAVAKAIQDDVDGFCVSNIDEAIELRQAGLSKPILILGVSEIEAVALAKEYDFT
                     LTVAGLEWIQALLDKEVDLTGLTVHLKIDSGMGRIGFREASEVEQAQDLLQQHGVRVE
                     GIFTHFATADEESDDYFNAQLERFKTILASMKEVPELVHASNSATTLWHVETIFNAVR
                     MGDAMYGLNPSGAVLALPYDLIPALTLESALVHIKTVPAGACMGYGATYQTDSEQVIA
                     TVPIGYADGWTRDMQNFSVLVDGQACPIVGRVSMDQITIRLPKPYPLGTKVTLIGSNG
                     DKEITATQVATYRVTINYEVVCLLSDRIPREYY"
     gene            29836..31851
                     /gene="recG"
                     /locus_tag="VQU30_000033"
     CDS             29836..31851
                     /gene="recG"
                     /locus_tag="VQU30_000033"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001048793.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent DNA helicase RecG"
                     /protein_id="HET2446232.1"
                     /translation="MNLHQPLHVLPGVGPKSAEKYAKLGIENLQDLLLYFPFRYEDFK
                     IKQVLELEDGEKAVLSGQVVTPASVQYYGFKRNRLRFSLKQGEVVFAVNFFNQPYLAD
                     KIELGATLAVFGKWDRAKASLTGMKVLAQVEDDLQPVYRLAQGISQASLVKVIKTAFD
                     QGLDLLIEENLPQSLLDKYKLMSRCQAVRAMHFPKDLAEYKQALRRIKFEELFYFQMQ
                     LQMLKSENRVQGSGLVLNWSQEKVTAVKVSLPFALTQAQEKSLQEILTDMKSDHHMNR
                     LLQGDVGSGKTVVAGLAMFAAVTAGYQAALMVPTEILAEQHFESLQNLFPNLKLALLT
                     GSLKAAEKREVLETIAKGEADLIIGTHALIQDGVEYARLGLIIIDEQHRFGVGQRRIL
                     REKGDNPDVLMMTATPIPRTLAITAFGDMDVSIIDQMPAGRKPIVTRWIKHEQLPQVL
                     TWLEGEIQKGSQAYVISPLIEESEALDLKNAIALSEELTTHFAGKAEVALLHGRMKSD
                     EKDQIMQDFKERKTDILVSTTVIEVGVNVPNATVMIIMDADRFGLSQLHQLRGRVGRG
                     DKQSYAVLVANPKTDSGKDRMRIMTETTNGFVLAEEDLKMRGSGEIFGTRQSGLPEFQ
                     VADIIEDFPILEEARKVASYISSIEAWQEDPEWRMIALHLEKKEHLD"
     gene            32167..33147
                     /locus_tag="VQU30_000034"
     CDS             32167..33147
                     /locus_tag="VQU30_000034"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844805.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetylxylan esterase"
                     /protein_id="HET2446233.1"
                     /translation="MKNPALLEEIKTYRGRDEVPEDFDAFWDGEVKNVSTLPSYHLEE
                     RDFHIPQVKCYELTFEGSKEGKVYARIVLPKSEEKVPLIFHFHGYMGRGWDWADMLGF
                     TVAGYGVVSMDVRGQSGYSQDGLRSPLGNTVKGHIIRGAMEGRDHLFYKDVYLDIYQL
                     VEIVASLSQVDEKRLSSYGASQGGALALVAAALNPRIQKTVAIYPFLSDFRRVIEIGN
                     TSEAYDELFRYFKFHDPFHETEEEIMATLAYIDVKNLAHRIQGEVKMITGLDDDVCYP
                     ITQFAIYNRLTCDKTYRIMPEYAHEAMNVFVNDQVYNWLCGSEIPFKYLK"
     gene            33952..34179
                     /locus_tag="VQU30_000035"
     CDS             33952..34179
                     /locus_tag="VQU30_000035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000576349.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2446234.1"
                     /translation="MIFKAFKTKKQRKRQVELLLTVFFDSFLIDLFLHLFGIVPFKLD
                     KILIVSLIIFPIISTSIYAYEKLFEKVFDKD"
     gene            34467..37364
                     /gene="nanA"
                     /locus_tag="VQU30_000036"
     CDS             34467..37364
                     /gene="nanA"
                     /locus_tag="VQU30_000036"
                     /EC_number="3.2.1.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014632427.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG-anchored neuraminidase NanA"
                     /protein_id="HET2446235.1"
                     /translation="MNRSVQERKCRYSIRKLSVGAVSMIVGAVVFGTSPVLAQEGASE
                     QPLANETQLSGESSTLTDTEKSQPSSETELSGNKQEQERKDKQEEKIPRDYYARDLEN
                     VETVIEKEDVETNASNGQRVDLSSELDKLKKLENATVHMEFKPDAKAPAFYNLFSVSS
                     ATKKDEYFTMAVYNNTATLEGRGSDGKQFYNNYNDAPLKVKPGQWNSVTFTVEKPTAE
                     LPNGRVRLYVNGVLSRTSLKSGNFIKDMPDVTHVQIGATKRANNTVWGSNLQIRNLTV
                     YNRALTPEEVQKRSQLFKRSDLEKKLPEGAALTEKTDIFESGRNGKPNKDGIKSYRIP
                     ALLKTDKGTLIAGADERRLHSSDWGDIGMVIRRSEDNGKTWGNRVTITNLRDNPKASD
                     PSIGSPVNIDMVLVQDPETKRIFSIYDMFPEGKGIFGMSSQKEEAYKKIDGKTYQILY
                     REGEKGAYTIRENGTVYTPDGKATDYRVVVDPVKPAYSDKGDLYKGNQLLGNIYFTTN
                     KTSPFRIAKDSYLWMSYSDDDGKTWSAPQDITPMVKADWMKFLGVGPGTGIVLRNGPH
                     KGRILIPVYTTNNVSHLNGSQSSRVIYSDDHGKTWHAGEAVNDNRQVDGQKIHSSTMN
                     NRRAQNTESTVVQLNNGDVKLFMRGLTGDLQVATSKDGGVTWEKDIKRYPQVKDVYVQ
                     MSAIHTMHNGKEYIILSNAGGPNRENGMVHLARVEENGELTWLKHNPIQKGEFAYNSL
                     QELGNGEYGILYEHTEKGQNAYTLSFRKFNWEFLSKDLISPTEAKVKRTREMGKGEMG
                     KGVIGLEFDSEVLVNKAPTLQLANGKTATFLTQYDSKTLLFAVDKEDIGQEIIGIAKG
                     SIESMHNLPVNLAGARVPGGVNGSKAAVHEVPEFTGGVNGTEPAVHEIAEYKGSDSLV
                     TLTTKEDYTYKAPLAQQALPETGNKESDLLASLGLTAFFLGLFTLGKKREQ"
     gene            38379..38831
                     /locus_tag="VQU30_000037"
     CDS             38379..38831
                     /locus_tag="VQU30_000037"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000587452.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhcH/YjgK/YiaL family protein"
                     /protein_id="HET2446236.1"
                     /translation="MIITKISHLGTYVGVNPHFATLIDFLEKTGLENLTEGSIAIDGN
                     RLFGNCFTYLADGQAGAFFETHQKYLDIHLVLENEEAMAVTSPENVSVTQEYDEEKDI
                     ELYTGKVEQLVQLRAGECLITFPEDLHQPKVRINDEPVKKVVFKVAIS"
     gene            38850..40187
                     /locus_tag="VQU30_000038"
     CDS             38850..40187
                     /locus_tag="VQU30_000038"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000738772.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter substrate-binding protein"
                     /protein_id="HET2446237.1"
                     /translation="MKKMRKFLCLAGIALAAVALVACSGKKEATTSTEPPTELSGEIT
                     MWHSFTQGPRLESIQKSADAFMQKHPKTKIKIETFSWNDFYTKWTTGLANGNVPDIST
                     ALPNQVMEMVNSDALVPLNDSIKRIGQDKFNETALNEAKIGDDYYSVPLYSHAQVMWV
                     RTDLLKEHNIEVPKTWDQLYEASKKLKEAGVYGLSVPFGTNDLMATRFLNFYVRSGGG
                     SLLTKDLKADLTSQLAQDGIKYWVKLYKEISPQDSLNFNVLQQATLFYQGKTAFDFNS
                     GFHIGGINANSPQLIDSIDAYPIPKIKESDKDQGIETSNIPMVVWKNSKHPEVAKAFL
                     EALYNEEDYVKFLDSTPVGMLPTIKGISDSAAYKENETRKKFKHAEEVITEAVKKGTA
                     IGYENGPSVQAGMLTNQHIIEQMFQDIITNGTDPMKAAKEAEKQLNDLFEAVQ"
     gene            40266..41150
                     /locus_tag="VQU30_000039"
     CDS             40266..41150
                     /locus_tag="VQU30_000039"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011999669.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HET2446238.1"
                     /translation="MVKERNLTRWIFVLPAMIIVGLLFVYPFFSSIFYSFTNKHLIMP
                     NYKFVGLANYKAVLSDPNFFNAFFNSIKWTVFSLVGQVLVGFVLALALHRVRHFKKLY
                     RTLLIVPWAFPTIVIAFSWQWILNGVYGYLPNLIVKLGLMEHTPAFLTDSTWAFLCLV
                     FINIWFGAPMIMVNVLSALQTVPEEQFEAAKIDGASSWQVFKFIVFPHIKVVVGLLVV
                     LRTVWIFNNFDIIYLITGGGPANATTTLPIFAYNLGWGTKLLGRASAVTVLLFIFLVA
                     ICFIYFAIISKWEKEGRK"
     gene            41150..41983
                     /locus_tag="VQU30_000040"
     CDS             41150..41983
                     /locus_tag="VQU30_000040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016250560.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HET2446239.1"
                     /translation="MKKKSSIYLDILSHVLLVGATIVAIFPLVWIIISSVKGKGELTQ
                     YPTRFWPEQFTLDYFTHVINDLHFIDNIRNSLIIALATTLIAIIISAMAAYGIVRFFP
                     KLGAIMSRLLVITYIFPPILLAIPYSIAIAKVGLTNSLFGLMMVYLSFSVPYAVWLLV
                     GFFQTVPIGIEEAARIDGANKFVTFYKVVLPIVAPGIVATAIYTFINAWNEFLYALIL
                     INNTGKMTVAVALRSLNGSEILDWGDMMAASVIVVLPSIIFFSIIQNKIASGLSEGSV
                     K"
     gene            42001..44094
                     /gene="nanB"
                     /locus_tag="VQU30_000041"
     CDS             42001..44094
                     /gene="nanB"
                     /locus_tag="VQU30_000041"
                     /EC_number="3.2.1.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001042179.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="neuraminidase NanB"
                     /protein_id="HET2446240.1"
                     /translation="MNKRGLYSKLGISVVGISLLMGVPTLIHANELNYGQLSISPIFQ
                     GGSYQLNNKSIDISPLLLDKLSGESQTVVMKFKADEPNSLQALFGLSNSKAGFKNNYF
                     SIFMRDSGEIGVEIRDAQKGINYLFSRPASLWGKHKGQAVENTLVFVSDSKDKTYTMY
                     VNGIEVFSETVDTFLPISNINGIDKATLGAVNREGKEHYLAKRSIDEISLFNKAISDQ
                     EVSNIPLSNPFQLIFQSGDSTQANYFRIPTLYTLSSGRVLSSIDARYGGTHDSKSKIN
                     IATSYSDDNGKTWSEPIFAMKFNDYEEQLVYWPRDNKLKNSQISGSASFIDSSIVEDK
                     KSGKTILLADVMPAGIGNNNANKADSGFKEINGHYYLKLKKNGDNDFRYTVRENGVVY
                     DETTNKPTNYTINDKYEVLEGGKSLTVEQYSVDFDSGSLRERHNGKQVPMNVFYKDSL
                     FKVTPTNYIAMTTSQNREESWEQFKLLPPFLGEKHNGTYLCPGQGLALKSSNRLIFAT
                     YTSGELTYLISDDSGQTWKKSSASIPFKNATAEAQMVELRDGVIRTFFRTTTGKIAYM
                     TSRDSGETWSEVSYIDGIQQTSYGTQVSAIKYSQLIDGKEAVILSTPNSRSGRKGGQL
                     VVGLVNKEDDSIDWKYHYDIDLPSYGYAYSAITELPNHHIGVLFEKYDSWSRNELHLS
                     NVVQYIDLEINDLTK"
     gene            44106..45209
                     /locus_tag="VQU30_000042"
     CDS             44106..45209
                     /locus_tag="VQU30_000042"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000241731.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HET2446241.1"
                     /translation="MVKYGVVGAGYFGAELARYMQKNDGAEITLLYDPDNAEAIAEEL
                     GAKVASSLDELVSSDEVDCVIVATPNNLHKEPVIKAAQHGKNVFCEKPIALSYQDCRE
                     MVDACKENNVTFMAGHIMNFFNGVHHAKELINQGVIGDVLYCHTARNGWEEQQPSVSW
                     KKIREKSGGHLYHHIHELDCVQFLMGGMPETVTMTGGNVAHEGEHFGDEDDMIFVNME
                     FSNKRFALLEWGSAYRWGEHYVLIQGSKGAIRLDLFNCKGTLKLDGQESYFLIHESQE
                     EDDDRTRIYHSTEMDGAIAYGKPGKRTPLWLSSVIDKEMRYLHEIMEGAPVSEEFAKL
                     LTGEAALEAIATADACTQSMFEDRKVKLSEIVK"
     gene            45383..46081
                     /locus_tag="VQU30_000043"
     CDS             45383..46081
                     /locus_tag="VQU30_000043"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398897.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmannosamine-6-phosphate 2-epimerase"
                     /protein_id="HET2446242.1"
                     /translation="MPQISKEALIEQIKDGIIVSCQALPHEPLYTEAGGVIPLLVKAA
                     EQGGAVGIRANSVRDIKEIKEVTKLPIIGIIKRDYPPQEPFITATMKEVDELAELDIE
                     VIALDCTKRERYDGLEIQEFIRQVKEKYPNQLLMADTSIFEEGLAAVEAGIDFVGTTL
                     SGYTSYSPKVDGPDFELIKKLCDAGVDVIAEGKIHTPEQAKQILEYGVRGIVVGGAIT
                     RPKEITERFVASLK"
     gene            46100..47617
                     /locus_tag="VQU30_000044"
     CDS             46100..47617
                     /locus_tag="VQU30_000044"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000477452.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HET2446243.1"
                     /translation="MFKVLQKVGKAFMLPIAILPAAGLLLGIGGALSNPTTIATYPIL
                     DNSIFQSIFQVMSSAGEVVFSNLSLLLCVGLCIGLAKRDKGTAALAGVTGYLVMTATI
                     KALVKLFMAEGSAIDTGVIGALVVGIVAVYLHNRYNNIQLPSALGFFGGSRFVPIVTS
                     FSSILIGFVFFVIWPPFQQLLVSTGGYISQAGPIGTFLYGFLMRLSGAVGLHHIIYPM
                     FWYTELGGVETVAGQTVVGAQKIFFAQLADLAHSGLFTEGTRFFAGRFSTMMFGLPAA
                     CLAMYHSVPKNRRKKYAGLFLGVALTSFITGITEPIEFMFLFVSPVLYVVHAFLDGVS
                     FFIADVLNISIGNTFSGGVIDFTLFGILQGNAKTNWVLQIPFGLIWSVLYYIIFRWFI
                     TQFNVLTPGRGEEVDSKEISESADSTSNTADYLKQDSLQIIRALGGSNNIEDVDACVT
                     RLRVAVKEVNQVDKALLKQIGAVDVLEVKGGIQAIYGAKAILYKNSINEILGVDD"
     gene            47742..49070
                     /locus_tag="VQU30_000045"
     CDS             47742..49070
                     /locus_tag="VQU30_000045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000672126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter substrate-binding
                     protein"
                     /protein_id="HET2446244.1"
                     /translation="MKFRKLACTVLAGAAVLGLAACGNSGGSKDAAKSGGDGAKTEIT
                     WWAFPVFTQEKTGDGVGTYEKSIIEAFEKANPDIKVKLETIDFKSGPEKITTAIEAGT
                     APDVLFDAPGRIIQYGKNGKLAELNDLFTDEFVKDVNNENIVQASKAGDKAYMYPISS
                     APFYMAMNKKMLEDAGVANLVKEGWTTDDFEKVLKALKDKGYTPGSLFSSGQGGDQGT
                     RAFISNLYSGSVTDEKVSKYTTDDPKFVKGLEKATSWIKDNLINNGSQFDGGADIQNF
                     ANGQTSYTILWAPAQNGIQAKLLEASKVEVVEVPFPSDEGKPALEYLVNGFAVFNNKD
                     DKKVAASKKFIQFIADDKEWGPKDVVRTGAFPVRTSFGKLYEDKRMETISGWTQYYSP
                     YYNTIDGFAEMRTLWFPMLQSVSNGDEKPADALKAFTEKANETIKKAMKQ"
     gene            49322..50188
                     /locus_tag="VQU30_000046"
     CDS             49322..50188
                     /locus_tag="VQU30_000046"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001209417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HET2446245.1"
                     /translation="MRETVISYAFLAPVLFFFVIFVLAPMVMGFITSFFNYSMTKFEF
                     VGLDNYIRMFKDPVFTKSLINTVILVIGSVPVVVLFSLFVASQTYHQNVIARSFYRFV
                     FFLPVVTGSVAVTVVWKWIYDPLSGILNFVLKSSHIISQNISWLGDKNWALMAIMIIL
                     LTTSVGQPIILYIAAMGNIDNSLVEAARVDGATEFQVFWKIKWPSLLPTTLYIAIITT
                     INSFQCFALIQLLTSGGPNYSTSTLMYYLYEKAFQLTEYGYANTIGVFLAVMIAIVSF
                     VQFKVLGNDVEY"
     gene            50204..51043
                     /locus_tag="VQU30_000047"
     CDS             50204..51043
                     /locus_tag="VQU30_000047"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398901.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HET2446246.1"
                     /translation="MQSTEKKPLTAFTVISTIILLLLTVLFIFPFYWILTGAFKSQPD
                     TIVIPPQWFPKMPTMENFQQLMVQNPALQWMWNSVFISLVTMFLVCATSSLAGYVLAK
                     KRFYGQRILFAIFIAAMALPKQVVLVPLVRIVNFMGIHDTLWAVILPLIGWPFGVFLM
                     KQFSENIPTELLESAKIDGCGEIRTFWSVAFPIVKPGFAALAIFTFINTWNDYFMQLV
                     MLTSRNNLTISLGVATMQAEMATNYGLIMAGAALAAVPIVTVFLVFQKSFTQGITMGA
                     VKG"
     gene            51316..51768
                     /locus_tag="VQU30_000048"
     CDS             51316..51768
                     /locus_tag="VQU30_000048"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000575445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhcH/YjgK/YiaL family protein"
                     /protein_id="HET2446247.1"
                     /translation="MIFDDLKNITFYKGIHPNLDKAIDYLYQHRKDSFELGKYEIDGD
                     KVFLVVQENVLNQVENNQFEHHKNYADLHLLIEGHEYSSYGSRIKDEAVAFDEATDIG
                     FVHCHEHYPLLLGYHNFAIFFPGEPHQPTGYAGMEEKVRKYLFKILID"
     gene            51865..52209
                     /locus_tag="VQU30_000049"
     CDS             51865..52209
                     /locus_tag="VQU30_000049"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000254916.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2446248.1"
                     /translation="MVSSKHAARASFLDGQEITVDEMSWIINGIVNALIGRYIKLGTY
                     AAKYGIGIARSILSRAAATAAARVGLLTKISGWILRVAVNVADVYGNFANNIAAAWDA
                     YDKIPNNGRINF"
     gene            52493..53137
                     /locus_tag="VQU30_000050"
     CDS             52493..53137
                     /locus_tag="VQU30_000050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000057467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YesL family protein"
                     /protein_id="HET2446249.1"
                     /translation="MAQKGVSLIKAAFDTDNFLMRFSEKVLDIVTANLLFVVSCLPIV
                     TIGVAKISLYETMFEVKKSRRVPVFKIYLRSFKQNLKLGLQLGLMELGIVFLTLSDLY
                     LFWGQTALPFQLLKAICLGILIFLTIVMLASYPIAARYDLSWKEILQKGLMLASFNFP
                     WFFLMLAILVLIVMVLYLSAFSLLLGGSVFLLFGFGLLVFIQTGLMEKIFAKYQ"
     gene            53306..54223
                     /locus_tag="VQU30_000051"
     CDS             53306..54223
                     /locus_tag="VQU30_000051"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002894436.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrodipicolinate synthase family protein"
                     /protein_id="HET2446250.1"
                     /translation="MSDLKKYEGVIPAFYACYDEQGEVSPERTRALVQYFIDKGVQGL
                     YVNGSSGECIYQSVEDRKLILEEVMAVAKGKLTIIAHVACNNTKDSMELARHAESLGV
                     DAIATIPPIYFRLPEYSVAKYWNDISSAAPNTDYVIYNIPQLAGVALTPSLYTEMLKN
                     PRVIGVKNSSMPVQDIQTFVSLGGEDHIVFNGPDEQFLGGRLMGAKAGIGGTYGAMPE
                     LFLKLNQLIADKDLETARELQYAINAIIGKLTATHGNMYGVIKEVLKINEGLNIGSVR
                     SPLTPVTEEDRPVVEAAAALIRETKESFL"
     gene            54241..55125
                     /locus_tag="VQU30_000052"
     CDS             54241..55125
                     /locus_tag="VQU30_000052"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HET2446251.1"
                     /translation="MTYYVAIDIGGTNIKYGLVDQEGQLLESHEMPTEAHKGGPHILQ
                     KTKDIVASYLEKGPVAGVAISSAGMVDPDKGEIFYAGPQIPNYAGTQFKKEIEESFTI
                     PCEIENDVNCAGLAEAVSGSGKGASVTLCLTIGTGIGGCLIMDRKVFHGFSNSACEVG
                     YMHMQDGAFQDLASTTALVKYVAEAHGEDVDQWNGRRIFKEATEGNKICMEGIDRMVD
                     YLGKGLANICYVANPEVVILGGGIMGQEAILKPKIRTALKEALVPSLAEKTRLEFAHH
                     QNTAGMLGAYYHFKTKQS"
     gene            complement(55141..55992)
                     /locus_tag="VQU30_000053"
     CDS             complement(55141..55992)
                     /locus_tag="VQU30_000053"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HET2446252.1"
                     /translation="MDKPDIATIIDSHFEEMTDLEQEIARYFLQAETITDDLSSQQVT
                     QKLHISQAALTRFAKKCGFTGYREFIFQYQHQAENQANRVSKHSPLTKRVLRSYSNMR
                     EQTQDLIDEIQLERIAQLIEDAERIYFFGTGSSGLVAREMKLRFMRLGVVCEALTDQD
                     GFAWTTSIMDENCLVLGFSLSGSTPSILDSLLDAKEMGAKTVLFTSVPNKDSQTYTET
                     VLVATHSQPSYIQRISAQLPMLFFIDLIYAYFLEINRESKEKIFNSYWENKKLNGYRR
                     QKRVRKS"
     gene            56192..58249
                     /gene="pbp2b"
                     /locus_tag="VQU30_000054"
     CDS             56192..58249
                     /gene="pbp2b"
                     /locus_tag="VQU30_000054"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001829432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein 2B"
                     /protein_id="HET2446253.1"
                     /translation="MRLICMRKFNSHSIPIRLNLLFSIVILLFMTIIGRLLYMQVLNK
                     DFYEKKLASASQTKITSSSARGEIYDASGKPLVENTLKQVVSFTRSNKMTATDLKETA
                     KKLLTYVSISSPNLTKRQLADYYLADPEIYKKTVEALPSEKRLDSDGNRLSESELYNN
                     AVDSVQTSQLNYTEDEKKEIYLFSQLNAVGNFATGTIATDPLNDSQVAVIASISKEMP
                     GISISTSWDRKVLETSLSSIVGSVSSEKAGLPAEEAEAYLKKGYSLNDRVGTSYLEKQ
                     YEETLQGKRSVKEIHLDKYGNMESVDTIEEGSKGNNIKLTIDLAFQDSVDALLKSYFN
                     SELENGGAKYSEGVYAVALNPKTGAVLSMSGIKHDLKTGELTPDSLGTVTNVFVPGSV
                     VKAATISSGWENGVLSGNQTLTDQSIVFQGSAPINSWYTQAYGSFPITAVQALEYSSN
                     TYMVQTALGLMGQTYQPNMFVGTSNLESAMEKLRSTFGEYGLGTATGIDLPDESTGFV
                     PKEYSFANYITNAFGQFDNYTPMQLAQYVATIANNGVRVAPRIVEGIYGNNDKGGLGD
                     LIQQLQPTEINKVNISDSDMSILHQGFYQVAHGTSGLTTGRAFSNGALVSISGKTGTA
                     ESYVADGQQATNTNAVAYAPSDNPQIAVAVVFPHNTNLTNGVGPSIARDIINLYQKYH
                     PMN"
     gene            58260..58856
                     /gene="recR"
                     /locus_tag="VQU30_000055"
     CDS             58260..58856
                     /gene="recR"
                     /locus_tag="VQU30_000055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002896112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombination protein RecR"
                     /protein_id="HET2446254.1"
                     /translation="MLYPTPIAKLIDSYSKLPGIGIKTATRLAFYTIGMSADDVNEFA
                     KNLLSAKRELTYCSICGRLTDDDPCSICTDPTRDQTTILVLEDSRDVAAMENIQEYHG
                     LYHVLHGLISPMNGISPDDINLKSLMTRLMDSEVSEVIVATNATADGEATSMYLSRLL
                     KPAGIKVTRLARGLAVGADIEYADEVTLLRAIENRTEL"
     gene            59032..60075
                     /locus_tag="VQU30_000056"
     CDS             59032..60075
                     /locus_tag="VQU30_000056"
                     /EC_number="6.3.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000814683.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--D-alanine ligase"
                     /protein_id="HET2446255.1"
                     /translation="MKQTIILLYGGRSAEREVSVLSAESVMRAVNYDHFTVKTFFISQ
                     SGDFIKTQEFSHAPGQEDRLMTNETIDWDKKVAPSAIYEEGAVVFPVLHGPMGEDGSV
                     QGFLEVLKMPYVGCNILSSSLAMDKITTKRVLESAGIAQVPYVAIVEGDDVTAKIAEV
                     EEKLAYPVFTKPSNMGSSVGISKSENQEELRQALKLAFRYDSRVLVEQGVNAREIEVG
                     LLGNYDVKSTLPGEVVKDVAFYDYDAKYIDNKITMDIPAKISDDVVAVMRQNAETAFR
                     AIGGLGLSRCDFFYTDKGEIFLNELNTMPGFTQWSMYPLLWDNMGISYPELIERLVDL
                     AKESFDKREAHLI"
     gene            60159..61532
                     /locus_tag="VQU30_000057"
     CDS             60159..61532
                     /locus_tag="VQU30_000057"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000778684.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-
                     alanine ligase"
                     /protein_id="HET2446256.1"
                     /translation="MKLTIHEVAQVVGAKNDISIFEDTQLEKAEFDSRLIGTGDLFVP
                     LKGVRDGHDFIERAFENGAAATLSEKEVANHPYILVDDVLTAFQQLAAYYLEKTAVDV
                     FAVTGSNGKTTTKDMLAHLLSTRYKTYKTQGNYNNEIGLPYTVLHMPEGTEKLVLEMG
                     QDHLGDIHLLSELARPKTAIVTLVGEAHLAFFKDRSEIAKGKMQIADGMASGSLLLAP
                     ADPIVEDYLPTDKKVVRFGQGAELEITDLVERKDSLTFKANFLEQVLDLPVTGKYNAT
                     NAMIASYVALQEGVSEEQIRLAFQHLELTRNRTEWKKAANGADILSDVYNANPTAMKL
                     ILETFSAIPANEGGKKIAVLADMKELGVQSVQLHNQMILSLSPDVLDTVIFYGEDIAE
                     LAQLASQMFPIGHVYYFKKTEDQDQFEDLVKQVKESLGAHDQILLKGSNSMNLAKLVE
                     SLENEDK"
     gene            61519..62130
                     /locus_tag="VQU30_000058"
     CDS             61519..62130
                     /locus_tag="VQU30_000058"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863589.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HET2446257.1"
                     /translation="MKTSDFVKYLQRMIAITDTGLTFTKDPFDRERYEDLRDLLSEML
                     NQASDLDSEEVAEVLKPTSAYATPLMDVRAWIVEDEKICLVRGQGEDSWALPGGFGEV
                     GYSPTENILKEIEEETGFKAKVERLLAVFDTNRFQLQSKQYAKFVFECKLLDGQFQEN
                     QEIADLQFFAIDPLPNLSEKRITKEQIEILWQVYQGQREQYLD"
     gene            62221..62925
                     /locus_tag="VQU30_000059"
     CDS             62221..62925
                     /locus_tag="VQU30_000059"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001055242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR02206 family membrane protein"
                     /protein_id="HET2446258.1"
                     /translation="MNLWDIFFTTQATEPPKFDLFWYVSLFTLLALTFYTAHRYREKK
                     VYQRFFQILQTVQLILLYGWYWVNHMPLSESLPFYHCRMAMFVVLLLPGQSKYKQYFA
                     LLGTFGTLAAFVYPVPDAYPFPHITILSFIFGHLALLGNSLVYLLRQYNARLLDVKGI
                     FLMTFALNALIFVVNLVTGGDYGFLTKPPLVGDHGLVANYLLVSIVLVATISLTKKIL
                     EFFLAQEAEKMIAKEA"
     gene            63144..64517
                     /gene="ftsA"
                     /locus_tag="VQU30_000060"
     CDS             63144..64517
                     /gene="ftsA"
                     /locus_tag="VQU30_000060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000090410.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsA"
                     /protein_id="HET2446259.1"
                     /translation="MAREGFFTGLDIGTSSVKVLVAEQRNGELNVIGVSNAKSKGVKD
                     GIIVDIDAAATAIKSAISQAEEKAGISIKSVNVGLPGNLLQVEPTQGMIPVTSDTKEI
                     TDQDVENVVKSALTKSMTPDREVITFIPEEFIVDGFQGIRDPRGMMGVRLEMRGLLYT
                     GPRTILHNLRKTVERAGVQVENIIISPLAMVQSVLNEGEREFGATVIDMGAGQTTVAT
                     IRNQELQFTHILQEGGDYVTKDISKVLKTSRKLAEGLKLNYGEAYPPLASKETFQVEV
                     IGEVEAVEVTEAYLSEIISARIKHILEQIKQELDRRRLLDLPGGIVLIGGNAILPGMV
                     ELAQEVFGVRVKLYVPNQVGIRNPAFAHVISLSEFAGQLTEVNLLAQGAIKGENDLSH
                     QPISFGGMLQKTAQFVQSTPVQPAPAPEVESVAPTEPMADFQQASQNKPKLADRFRGL
                     IGSMFDE"
     gene            64534..65793
                     /gene="ftsZ"
                     /locus_tag="VQU30_000061"
     CDS             64534..65793
                     /gene="ftsZ"
                     /locus_tag="VQU30_000061"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000144288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsZ"
                     /protein_id="HET2446260.1"
                     /translation="MTFSFDTAAAQGAVIKVIGVGGGGGNAINRMVDEGVTGVEFIAA
                     NTDVQALSSTKAETVIQLGPKLTRGLGAGGQPEVGRKAAEESEETLTEAISGADMVFI
                     TAGMGGGSGTGAAPVIARIAKDLGALTVGVVTRPFGFEGSKRGQFAVEGINQLREHVD
                     TLLIISNNNLLEIVDKKTPLLEALSEADNVLRQGVQGITDLITNPGLINLDFADVKTV
                     MANKGNALMGIGIGSGEERVVEAARKAIYSPLLETTIDGAEDVIVNVTGGLDLTLIEA
                     EEASQIVNQAAGQGVNIWLGTSIDESMRDEIRVTVVATGVRQDRVEKVVAPQARSATN
                     YRETVKPAHSHGFDRHFDMAETVELPKQNPRRLEPTQASAFGDWDLRRESIVRTTDSV
                     VSPVERFEAPISQDEDELDTPPFFKNR"
     gene            65798..66469
                     /locus_tag="VQU30_000062"
     CDS             65798..66469
                     /locus_tag="VQU30_000062"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YggS family pyridoxal phosphate-dependent
                     enzyme"
                     /protein_id="HET2446261.1"
                     /translation="MNVKENTELVFREVAEASLSAHRESGSVSVIAVTKYVDVPTAEA
                     LLPLGVHHIGENRVDKFLEKYEALKDRDVTWHLIGTLQRRKVKDVIQYVDYFHALDSV
                     KLAGEIQKRSDRVIKCFLQVNISKEESKHGFSREELLEILPELARLDKIEYVGLMTMA
                     PFEASSEQLKEIFKATQDLQREIQEKQIPNMPMTELSMGMSRDYKEAIQFGSTFVRIG
                     TSFFK"
     gene            66479..67018
                     /locus_tag="VQU30_000063"
     CDS             66479..67018
                     /locus_tag="VQU30_000063"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000053379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein SepF"
                     /protein_id="HET2446262.1"
                     /translation="MSLKDRFDRFIDYFTEDEDSSLPYEKRDEPVFTPVNSSQEPALP
                     MNQPSQSAGTKENNITRLHARQQELANQSQRATDKVIIDVRYPRKYEDATEIVDLLAG
                     NESILIDFQYMTEVQARRCLDYLDGACHVLAGNLKKVASTMYLLTPVNVIVNVEDIRL
                     PDEDQQGEFGFDMKRNRVR"
     gene            67018..67281
                     /locus_tag="VQU30_000064"
     CDS             67018..67281
                     /locus_tag="VQU30_000064"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000576515.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YggT family protein"
                     /protein_id="HET2446263.1"
                     /translation="MIFLIRMIYNAVDIYSLILVAFAVMSWFPGAYESSLGRWIVALV
                     KPVLAPLQRLPLQIAGLDLSVWVAIVLVRFLGENLVRFLAMIG"
     gene            67278..67962
                     /locus_tag="VQU30_000065"
                     /pseudo
     CDS             67278..67962
                     /locus_tag="VQU30_000065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398113.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding protein"
     gene            67971..68759
                     /gene="divIVA"
                     /locus_tag="VQU30_000066"
     CDS             67971..68759
                     /gene="divIVA"
                     /locus_tag="VQU30_000066"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001810114.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein DivIVA"
                     /protein_id="HET2446264.1"
                     /translation="MPITSLEIKDKTFGTRFRGFDPEEVDEFLDIVVRDYEDLVRANH
                     DKNLRIKSLEERLSYFDEIKDSLSQSVLIAQDTAERVKQAAHERSNNIIHQAEQDAQR
                     LLEEAKYKANEILRQATDNAKKVAVETEELKNKSRVFHQRLKSTIESQLAIVESSDWE
                     DILRPTATYLQTSDEAFKEVVSEVLGEPIPAPIEEEPIDMTRQFSQAEMEELQARIEV
                     ADKELSEFEAQIKQEVETPTPVVSPQVEEEPLLIQLAQCMKNQK"
     gene            69107..71899
                     /locus_tag="VQU30_000067"
     CDS             69107..71899
                     /locus_tag="VQU30_000067"
                     /EC_number="6.1.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012000155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isoleucine--tRNA ligase"
                     /protein_id="HET2446265.1"
                     /translation="MKLKDTLNLGKTEFPMRAGLPTKEPVWQKEWEDAKLYQRRQELN
                     QGKPHFTLHDGPPYANGNIHVGHAMNKISKDIIVRSKSMSGFYAPFIPGWDTHGLPIE
                     QVLSKQGVKRKEMDLVEYLKLCREYALSQVDKQREDFKRLGVSGDWENPYVTLTPDYE
                     AAQIRVFGEMANKGYIYRGAKPVYWSWSSESALAEAEIEYHDLVSTSLYYANKVKDGK
                     GVLDTDTYIVVWTTTPFTITASRGLTVGADIDYVLVQPAGEARKFVVAAELLTSLSEK
                     FGWADVQVLETYRGQELNHIVTEHPWDTAVEELVILGDHVTTDSGTGIVHTAPGFGED
                     DYNVGIANNLEVAVTVDERGIMMKNAGPEFEGQFYEKVVPTVIEKLGNLLLAQEEISH
                     SYPFDWRTKKPIIWRAVPQWFASVSKFRQEILDEIEKVKFHSEWGKVRLYNMIRDRGD
                     WVISRQRAWGVPLPIFYAEDGTAIMVAETIEHVAQLFEEHGSSIWWERDAKDLLPEGF
                     THPGSPNGEFKKETDIMDVWFDSGSSWNGVVVNRPELTYPADLYLEGSDQYRGWFNSS
                     LITSVANHGVAPYKQILSQGFALDGKGEKMSKSLGNTIAPSDVEKQFGAEILRLWVTS
                     VDSSNDVRISMDILSQVSETYRKIRNTLRFLIANTSDFNPAQDTVAYDELRSVDKYMT
                     IRFNQLVKTIRDAYANFEFLTIYKALVNFINVDLSAFYLDFAKDVVYIEGAKSLERRQ
                     MQTVFYDILVKITKLLTPILPHTAEEIWSYLEFEAEDFVQLSELPEVQTFANQEEILD
                     TWAAFMDFRGQAQKALEEARNAKVIGKSLEAHLTVYPNEVVKTLLEAVNSNVAQLLIV
                     SELTIAEEPAPEAALSFEDVVFTVERAAGEVCDRCRRIDPTTAERSYHAVICDHCASI
                     VEENFADAVAEGFEEK"
     gene            72309..72671
                     /locus_tag="VQU30_000068"
     CDS             72309..72671
                     /locus_tag="VQU30_000068"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000842495.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2446266.1"
                     /translation="MKSSGIVGLVGGILLLICPFVLLGTAVNTAATTLNGGATAGAFS
                     GVALLLNALKIANLVLGIIAIVYYKGDKHVGAAPSVLMIVSGEVSLIPFLGWVGGILA
                     IIGGSLFLATLKKFKSEE"
     gene            73206..73898
                     /locus_tag="VQU30_000069"
     CDS             73206..73898
                     /locus_tag="VQU30_000069"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006703946.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglycerate mutase"
                     /protein_id="HET2446267.1"
                     /translation="MVKLVFARHGESEWNKANLFTGWADVDLSEKGTQQAIDAGKLIK
                     EAGIEFDQAYTSVLKRAIKTTNLALEASDQLWVPVEKSWRLNERHYGGLTGKNKAEAA
                     EQFGDEQVHIWRRSYDVLPPNMDRDDEHSAHTDRRYASLDDSVIPDAENLKVTLERAL
                     PFWEDKIAPALKDGKNVFVGAHGNSIRALVKHIKGLSDDEIMDVEIPNFPPLVFEFDE
                     KLNVVSEYYLGK"
     gene            73951..76362
                     /locus_tag="VQU30_000070"
     CDS             73951..76362
                     /locus_tag="VQU30_000070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000620712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 95 protein"
                     /protein_id="HET2446268.1"
                     /translation="MIRNKKQDYVLAYKQPASTTYMGWEEEALPIGNGSLGAKVFGLI
                     GAERIQFNEKSLWSGGPLPDSSDYQGGNLQDQYVFLAEIRQALEKRDYNLAKELAEQH
                     LIGPKTSQYGTYLSFGDIHIEFSQQGTTLSQVTDYQRQLNISKALATTSYVYKGTRFE
                     RKAFASFPDDLLIQCFTKEGLETLDFTIELSLTCDLASDGKYEQEKSDYKECKLDITD
                     SHILMKGRVKDNDLRFASYLAWETDGDIRVWSDRVQISGASYANLFLAAKTDFAQNPA
                     SNYRKKLDLEQQVIDLVDTAKEKGYTQLKSRHIEDYQALFQRVQLDLEADVDASTTDD
                     LLKNYKPQEGQALEELFFQYGRYLLISSSRDCPDALPANLQGVWNAVDNPPWNSDYHL
                     NVNLQMNYWPAYVTNLLETVFPVINYVDDLRVYGRLAAVKYAGIVSQKGEENGWLVHT
                     QATPFGWTAPGWDYYWGWSPAANAWMMQTVYEAYSFYRDQDYLREKIYPMLRETVRFW
                     NAFLHKDQQAQRWVSSPSYSPEHGPISIGNTYDQSLIWQLFHDFIQAAQELGLDEDLL
                     TEVKEKSDLLNPLQITQSGRIREWYEEEEQYFQNEKVEAQHRHASHLVGLYSGNLFSY
                     KGQEYIEAARAILNDRGDGGTGWSKANKINLWARLGDGNRAHKLLAEQLKTSTLPNLW
                     CSHPPFQIDGNFGATSGMAEMLLQSHAAYLVPLAALPDAWSTGSVSGLMARGHFEVSM
                     SWEDKKLLQLTILSRSGGDLRVSYPDIEKSVIKMNQEKIKAKCMGKDCISVATAEGDL
                     VQFYF"
     gene            76612..77313
                     /locus_tag="VQU30_000071"
     CDS             76612..77313
                     /locus_tag="VQU30_000071"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399621.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET2446269.1"
                     /translation="MAYIEMKHCYKRYQVGDTEIVANRDVNFEIEKGELVIILGASGA
                     GKSTVLNLLGGMDTNDEGEIWIDGVNIADYSSHQRTNYRRNDVGFVFQFYNLVSNLTA
                     KENVELASEIVTDALNPDQVLTDVGLAHRLNNFPAQLSGGEQQRVSIARAVAKNPKIL
                     LCDEPTGALDYQTGKQVLKILQDMSRQKGATVIIVTHNGALAPIADRVIQMHDASVKD
                     VVLNQHPQDIDSLEY"
     gene            77315..80015
                     /locus_tag="VQU30_000072"
                     /pseudo
     CDS             77315..80015
                     /locus_tag="VQU30_000072"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000595876.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="FtsX-like permease family protein"
     gene            complement(80111..80602)
                     /gene="tpx"
                     /locus_tag="VQU30_000073"
     CDS             complement(80111..80602)
                     /gene="tpx"
                     /locus_tag="VQU30_000073"
                     /EC_number="1.11.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004245092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiol peroxidase"
                     /protein_id="HET2446270.1"
                     /translation="MVTFLGNPVSFTGKQLQVGDKALDFSLTTTDLSKKSLADFDGKK
                     KVLSVVPSIDTGICSTQTRRFNEELAGLDNTVVLTVSMDLPFAQKRWCGAEGLDNAIM
                     LSDYFDHSFGRDYALLINEWHLLARAVFVLDTDNTIRYVEYVDNINSEPNFEAAIAAA
                     KAL"
     gene            complement(80725..81654)
                     /gene="psaA"
                     /locus_tag="VQU30_000074"
     CDS             complement(80725..81654)
                     /gene="psaA"
                     /locus_tag="VQU30_000074"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000733059.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter substrate-binding
                     lipoprotein/adhesin PsaA"
                     /protein_id="HET2446271.1"
                     /translation="MKKLGTLLVLFLSAIILVACASGKKDTTSGQKLKVVATNSIIAD
                     ITKNIAGDKIDLHSIVPIGQDPHEYEPLPEDVKKTSEADLIFYNGINLETGGNAWFTK
                     LVENAKKTENKDYFAVSDGVDVIYLEGQNEKGKEDPHAWLNLENGIIFAKNIAKQLSA
                     KDPNNKEFYEKNLKEYTDKLDKLDKESKDKFNKIPAEKKLIVTSEGAFKYFSKAYGVP
                     SAYIWEINTEEEGTPEQIKTLVEKLRQTKVPSLFVESSVDDRPMKTVSQDTNIPIYAQ
                     IFTDSIAEQGKEGDSYYSMMKYNLDKIAEGLAK"
     gene            complement(81686..82534)
                     /locus_tag="VQU30_000075"
     CDS             complement(81686..82534)
                     /locus_tag="VQU30_000075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000559784.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter permease"
                     /protein_id="HET2446272.1"
                     /translation="MIAEFIDGLQKFHFLQNALITAIVVGIVAGAVGCFIILRGMSLM
                     GDAISHAVLPGVALSFILGLDFFIGAIVFGLLAAIIITYIKGNSIIKSDTAIGITFSS
                     FLALGIILIGVAKSSTDLFHILFGNILAVQDTDMFITMGVGAAILLLIWIFFKQLLIT
                     SFDELLAKAMGMPVNFYHYLLMVLLTLVSVTAMQSVGTILIVAMLITPAATAYLYANS
                     LKSMIFLSSTFGATASVLGLFIGYSFNVAAGSSIVLTAASFFLISFFIAPKQRYLKLK
                     NKHLLK"
     gene            complement(82531..83253)
                     /locus_tag="VQU30_000076"
     CDS             complement(82531..83253)
                     /locus_tag="VQU30_000076"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000619140.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter ATP-binding protein"
                     /protein_id="HET2446273.1"
                     /translation="MIRIENLSVSYKETLALKDISLVLHGPTITGIIGPNGAGKSTLL
                     KGMLGIIPHQGQAFLDDKEVKKSLHRIAYVEQKINIDYNFPIKVKECVSLGLFPSIPL
                     FRSLKAKHWKKVQEALEIVGLADYAERQISQLSGGQFQRVLIARCLVQEADYILLDEP
                     FAGIDSVSEEIIMNTLRDLKKAGKTVLIVHHDLSKIPHYFDQVLLVNREVIAFGPTKE
                     TFTETNLKEAYGNQLFFNGGDL"
BASE COUNT        25207 a        15193 c        18401 g        24546 t
ORIGIN      
        1 gaagataaag cctataacca tgcgctatct aaggagagaa gcaaggttga gaacatcttt
       61 gccaaagtaa aaacgtttaa aatgttttca acaacctatc gaaatcatcg taaacgcttc
      121 ggattacgaa tgaatttgat tgctggcatt atcaatcatg aactaggatt ctagttttgc
      181 aggaagtcta ctactttcct tattgtctgt aaatctactg accttgttgt ttatcccagt
      241 catggtttct agttcgggct cagagtttca aagtggatgg caagagcatc aattgattgc
      301 tgagaaggtt agtaaaacac ttgataagac atttgataag gatgtcagag aaattccgac
      361 cagtcagttt tatcaaaaat ttgtagatga gatgggaagg atttactcag gaaatttgat
      421 cctccaggag ctgataactg tgaatggagc ttataaagct acttatatcg gtgaactctc
      481 tagcaactaa tcattcttta aaatgatgac caataagagg cttgatttgg tgaatcaagt
      541 cttttttctc tcttttactg ccatttgtga taaaatagta tagaacgatt ttttacatga
      601 atgataaaac agaggtaaat atgacaatcg gtattgataa gattggtttt gcgaccagtc
      661 aatatgtctt gaaattacaa gacttagcag aagcgagggg aattgaccct gaaaaattaa
      721 gtaaaggact cttactcaag gaattgagta ttgcgcccct aactgaggac atcgtgacct
      781 tggcggccag tgctagtgac tctattttaa ctgagcaaga aagacaagaa gttgacatgg
      841 tcattgtggc taccgagtca ggaattgacc agagtaaggc tgcggccgtc tttgtgcatg
      901 gcttgctggg catccagccc tttgctcgta gtttcgagat taaagaagcc tgctatgggg
      961 cgacagctgc cctccattat gccaaattgc atgtggaaaa ttctccggag tccaaggtct
     1021 tggtcattgc cagtgatatt gccaaatatg gtattgaaac tccgggagaa ccaactcaag
     1081 gtgctggaag tgtagctatg ttgattacac aaaatccacg catgatggcc tttaataatg
     1141 acaatgtagc tcagacccgt gacatcatgg atttctggcg accaaattac tcgacaactc
     1201 cttatgtaaa tggtgtctat tctacccaac aatacttgga tagtttgaaa acgacttggc
     1261 ttgaatatca aaaacgctac cagcttactc tggatgattt tgcggctgtt tgtttccact
     1321 tgccttatcc taaattagcg ctaaaaggct tgaaaaaaat catggataag agcctgcctc
     1381 aagagaaaaa agacctctta caaaagcatt ttgaccagtc tattctctac agtcaaaagg
     1441 tggggaatat ctacacaggt tcacttttcc ttggactttt gtctctcttg gaaaatgcag
     1501 atagcttgaa agctggggat aaaatcgccc tttatagtta cggaagtgga gctgtggctg
     1561 agttcttcag tggtgaattg gttgaaggat atgaagctta tttggataaa gaccgcttga
     1621 acaagctcaa ccaacgaact gccttatccg ttgcagacta tgaaaaggtc ttttttgagg
     1681 aagtaaactt ggatgaaaca aactctgccc agtttgctgg ctatgaaaat caagattttg
     1741 ccttggttga aattctcgac caccaacgcc gttatagcaa ggttgaaaaa taatgaagat
     1801 aagttggaat ggattttcta aaaaatcata ccaagagcgc ctcgagctgt taaaagctca
     1861 ggcgctcctt agtcctgaga gacaagctag tctggagaag gatgaacaga tgagtgtgac
     1921 tgtggcagac cagctgagtg agaatgtagt gggaactttt tctctgcctt attcgctggt
     1981 tccggaggta cttgtcaacg gtcaggaata caccgttccc tatgtgacag aagaaccctc
     2041 tgtggttgcg gcggccagct atgccagcaa aatcatcaag cgtgcaggtg gttttactgc
     2101 acaagtccat cagcgccaga tgattgggca ggtagccctt tatcaagttg ctaatcctaa
     2161 actagcgcaa gagaagattg ccagcaagaa agcggagctc ttggagtttg ccaatcaagc
     2221 ctatccttct atcgttaaac gtggaggtgg ggcgcgtgat ctgcatgtcg agcagataaa
     2281 aggcgaacca gactttctcg ttgtttatat tcatgtcgat acccaggaag ccatgggtgc
     2341 caatatgctc aacaccatgc tggaagcctt gaaaccagtc ttagaagaac tcagtcaggg
     2401 acagagtctc ataggaatcc tgtccaacta cgcgaccgat tctctggtga ctgcaagctg
     2461 tcgcatggcc tttcgctact tgagccgcca aaaggatcaa ggacgagaga ttgcggagaa
     2521 aattgcgttg gctagtcagt ttgcgcaggc tgatccttac cgagctgcta ctcataataa
     2581 aggaattttt aatggtattg atgcgatttt gattgccact ggtaatgact ggcgtgccat
     2641 cgaagctggg gcccatgcct ttgccagtcg agatggacgc tatcaaggtc ttagttgctg
     2701 gacgctggac cttgaaagag aagaattggt cggtgagatg accctgccca tgcctgtagc
     2761 gactaagggt ggctctatcg gcctcaaccc acgtgtagct ttcagtcatg atctactagg
     2821 aaatccttct gccagagaat tagcccagat tatcgtgtcc atcggtcttg cccaaaattt
     2881 tgcagccctc aaagctttgg taagtacggg catccagcaa ggccacatga aactacaggc
     2941 caaatcccta gctctcctag ctggggctag tgaatctgaa gttgctcccc tagtagagcg
     3001 cctcatctca gataaaacct ttaacctaga gacagcccag cgctatctcg aaaatttaag
     3061 atcataaaaa actcagacga atcggtctga gttttcttgt gtttaaatac tttttcctgg
     3121 taatagtgta actggtaaga agtaaccagt tgtggcaact tccttgcctt caatcttttg
     3181 caagagaaga tcaatagtga gacaagcaat ctcttccaaa ggttgcttga tagtagccaa
     3241 ttgagggtag taattttcga taaagtaggt cccatcatag ccgatgacct tgagctcttt
     3301 tgggacagaa atgcccaatt cttgagcgat tttaatgacc agaatagctg tcaaatcatc
     3361 cgaagcaaaa atggcatctg gtttttcccg ggtcaagata ttcttgattt ccatttcttt
     3421 tctgacggga gaaaagtcac tggaaacatt gataatagga gcttttggga gtacggatgc
     3481 aaaaccagcg tggcgtagtc cggttggcga attggaattg tcattccctg taatcatgat
     3541 gatagtctgg gcacctgtct tgaccaaggt ttgggcagca agaaccccac cagcatagtt
     3601 gtcagaggag acgacaggga tgtctggcga taggtttcgg tcaaaggaaa taatcggcgc
     3661 tgtcacacga ttgtagtctt cgattcctag gttgtgacta ccagaaatga tgccgtccac
     3721 ctgattggct tccaacattt cgatgtattc gcgttccttc tcagaatcat gttcactgtt
     3781 gcagatgatg gtcttgtaac catttttgaa gagttggtgt tccaatttat caatcaattc
     3841 tgcatagaaa acattggaaa tattagggaa aatcaagccg attaacttag ctgattttcc
     3901 ttgcagacta cgagccaggt tgttgggttt atagcccaat tctcgcatgg cttcattgac
     3961 tttttggatg gttttctcag atagataccc ttttttattg ataacccgag aaacggtagt
     4021 aggactgacg cctgcaagtt tggcgacatc agttagtttt gcgaccataa tctaattcat
     4081 agtaagttcc agttgggttt ccagatttga tcaggatacc attttggtcc gcatgtggga
     4141 agacacgacc agaaaatact ttttctcctt tattgatgaa aatttcaaag acagagttat
     4201 cgatgaagat tgtagcagta gtagcctgat tctcgatagg gcaagaacga gttgtcccaa
     4261 attcttgggc atactgttct ccagcctggc tacgatccac tgtcacttga ccgtttacaa
     4321 ggtcaaagtt gattgaaagt cccttacctt ctttatcagc aagtaagaca atctcgctct
     4381 ggctattagc ttccaagttg agttcaagtt cgtaagtgtt cttggtttgg gaacggtttg
     4441 agaaggcttc ttcagaagca cgaaggtcct taatagcagc gactggatac tggtagagct
     4501 tgtcgtcttt gatagtgagt tccttgacca aagagaaggt tccttggtgg tcaaaacggt
     4561 cagatgggta agaaacatct ggcaaaccaa gccagctaac tgctagagca cgcccatcag
     4621 gagcgttgaa ggcttgagtt gcataggctt cgaaaccgta atccatgttt tgaagttgag
     4681 acacatctac cattttggca tttttagggt caaaggaagc cccaatctta tacatatttg
     4741 gaaagatatt atcgtagtct agaactttct tatccaatcc ttgtggacag tagagaagga
     4801 caggatgttc ctctacaaag accagattag gacattccat catgtaggca gtacggtcgt
     4861 tagcaaagtc aaggtcgcca actgcttgcc agtttgtgta gtcgttattg acagccttgt
     4921 agagacggac gaagcctttt ttctccaagt cctgtccacc gacgacagca tagtattgac
     4981 ttttaaagtt aaaaatttgt ggatcgcgga agtggtcagt agagtctgct ggctggtcaa
     5041 tcaagatctt gtcaatcttt gtaatcttac cctccttgtc catcaaagca ccgatctggt
     5101 atgggtgacg gatccagttt tcatcgcgaa catttcctgt ataaaatagg aataagttat
     5161 cgccaaattg catggcagaa ccagagtagg caccgtggct atctaatgga gtatctggta
     5221 aaactttgat tccagtttct ttaaagtgaa ccaaatcatc actttctagc tgtgcccaag
     5281 atttcaaacc gtgggctgca ccaaaaggaa aattctggta aaagaggatc cacttgccat
     5341 caaagtaaga aaagccattt gggtcgttga gaagtcctgt ttttggctca acatggtaat
     5401 gagtatgcca tggagattgt gccatatttt cctttatatg ttgaatttct tcttgcgtcc
     5461 aatcttgata aagtctgtaa cgacgctcag ttgtccattc cattcattcc tccaaaaatc
     5521 ttatcacttt taatagtaac tgttttcgat aaaaaatgca agccttttat gttaaaaaag
     5581 aggaaaaact gtcaaacgat tatcataaaa taaatacagg aaatcaatca aatttttacg
     5641 aaaatgtgaa agataatgaa ataaaagact ttttaaccaa ggtttcaaac ttatttttca
     5701 aggaattcct gatgaaacag tcaaaaacaa tcaatctaaa acttgcccac taagtggata
     5761 gaatattttt tctgcaaaac gcttgacata tttttaaaac atgataaaat aatagtcgta
     5821 agggcgaata aaatcgcttt caaacaagaa caaaatgtta tataaggaga tttttgcaaa
     5881 tgaacaatca ggaaattgca aaaaaagtca tcgatgcctt gggcggacgt gaaaatgtca
     5941 atagtgttgc ccactgtgcg actcgtctac gtgtcatggt caaagatgaa gagaaaatca
     6001 ataaagaagt gattgagaac ttggaaaaag ttcaaggtgc tttctttaac tcagggcaat
     6061 accaaattat ctttggtaca ggtacagtta acaaaatgta cgatgaagtt gttgtacttg
     6121 gcttaccaac atcatctaag gatgacatga aagcagaagt tgctaaacaa gggaactggt
     6181 tccaacgtgc tatccgtact ttcggtgatg ttttcgttcc aatcatccca gttatcgtag
     6241 cgacaggtct cttcatgggt gtgcgtggtc ttttcaacgc tcttgaaatg ccacttccag
     6301 gtgactttgc aacttacaca caaatcttga cagatacagc cttcatcatc ttgccaggtt
     6361 tggttgtgtg gtcaaccttc cgtgtatttg gtggaaatcc tgccgttggt atcgttcttg
     6421 gtatgatgct tgtctctggc tcacttccaa acgcttgggc agttgctcaa ggtggtgaag
     6481 taacagcgat gaacttcttt ggtttcatcc ctgttgttgg tttgcaaggt tccgttcttc
     6541 cagccttcat catcggggtt gtcggagcta aatttgaaaa agctgtccgc aaggttgttc
     6601 cagatgtcat tgacctcttg gtaacaccat tcgtgacact tttggtcatg tctatccttg
     6661 gactctttgt cattggacca gttttccacg ttgttgaaaa ctacatcctt attgctacaa
     6721 aagcgattct tagcatgcca tttggtcttg gtggtttctt gattggtggg gttcaccaat
     6781 tgatcgtcgt gtcaggtgtg caccacatct tcaacttgct tgaagtgcaa ttacttgctg
     6841 ctgaccatgc taacccattc aacgctatca tcacagctgc tatgacagct caaggtgctg
     6901 ctactgttgc ggttggtgtt aaaacaaaaa atccaaaact gaaaacactt gctttcccgg
     6961 ctgctctttc tgccttccta ggtattacag agcctgctat cttcggggtg aacttgcgct
     7021 tccgtaaacc attcttcctt tcattgattg ctggtgcaat cggtggtgga ttggcttcta
     7081 tccttggact tgctggtact ggtaatggta tcaccatcat ccctggtaca atgctttatg
     7141 ttggtaacgg acaacttcca caataccttc ttatggtagc tgtatcattt gcccttggtt
     7201 ttgctcttac ttacatgttt ggttacgaag atgaagtaga cgcaactgca gctgcaaaac
     7261 aagctgaagt ggctgaagaa aaagaagaag ttgcgccagc agctcttcaa aatgaaacac
     7321 ttgtaactcc tatcgtcggt gatgttgtcg ctcttgctga tgtcaatgac ccagtcttct
     7381 caagtggagc tatgggacaa ggtatcgctg tgaaaccaag tcaaggcgtg gtctatgcac
     7441 tagctgatgc tgaagtttca attgcctttc caacagggca cgcttttggt ttgaaaacaa
     7501 gaaatggtgc tgaagttttg attcacgttg gtattgacac tgtatctatg aacggtgacg
     7561 gttttgaagc aaaagttgct caaggtaata aggtgaaagc tggcgatgtt cttggaacat
     7621 ttgactcaaa caaaatcgct gcagctggac ttgatgatac aacaatggtt atcgttacaa
     7681 atacagctga ctacgcttca gtagctccag tcgcaacagg ttcagtttcg aagggggatg
     7741 ctgtgatcga agtgaaaatc taatcaatcc tctctaatgt gaaaacgaac aaatgacatg
     7801 tttgttcgtt tttattagat agtaagattt acagaggaaa atctaaaaaa tagagacatt
     7861 tagactttcg aagtatgcta taataaagaa aataaaaaca agaggtttat catgacaaaa
     7921 ttatatggaa gcttggaagc gggcggtaca aagtttgtct gtgctgtcgg tgatgaaaac
     7981 tttaacgttg tagaaaaaac acaatttcca acaacaactc caatcgaaac aatcgataaa
     8041 accattgagt tcttctcaaa attcgataac cttgctggtc ttgcagttgg ttcatttggg
     8101 ccgattgata ttgacaaaaa ctcaaaaact tatggcttta tcacgacgac tccaaaacca
     8161 aactgggcaa atgtggactt gcttggtgcc cttcgtcgcg ccctaaacgt gccaatgtac
     8221 ttcacaacag acgtaaacag ctctgcttac ggtgaaatgg ttgctcgtaa caatgctggt
     8281 ggtcgtatcg aaaacttggt ttactacaca atcggtacag gtatcggtgc aggcgtcatc
     8341 caacgtggtg agtttatcgg tggtgtgggt caccctgaaa tgggtcatta ttatgttgct
     8401 agacacccaa tggatattga aaaagagttt aagggtgttt gtcctttcca taagggatgt
     8461 ctagaaggtt atgcagctgg tacaagtttg gaagctcgta caggtgtacg tggggaaact
     8521 attgaactca acaaccctgt ttgggatgtt caagcctact atatcgctca agctgcggtt
     8581 aatgcgacag tgactttccg cccagacgtg attgtctttg gtggaggggt catggctcaa
     8641 caacatatgc tggaccgtgt ccgtgagaaa tttacatctc ttcttaatgg ttacctacca
     8701 gtaccagatg tgcgtgacta tatcgtgacg ccagcagtcg caggaaatgg ttctgccaca
     8761 cttgggaact ttgttcttgc aaaagaagtt tcaaaataaa gcacaaaatc cgcttgggaa
     8821 accaaacgga ttttgtggtt gaaaacaata tttttgagcc tttccttaag tgattacgga
     8881 cggtagcgac tttcttcgaa attccatacc taaactttga gcctagtgtc tcaaagtttc
     8941 cgaatacctg aaaccattag atttcaggtg tttctatcac ggcggaaagg ctaggtaagt
     9001 cctcgcctca ctatcgaaaa atatgcataa tttccatacc aaagtatatt tagtatcaag
     9061 ctatagttaa tctacgcttt aaaaatccac ttgggaaacc aaacggattt tttacgtgtc
     9121 aaagcatttg ccagaaaaag tcaataatat aggtcagacc gtaggtataa accacgaggg
     9181 taaagggttt ggtcagaatg atgatagtca tgtagcgctt gaaactcatc ttggtcaggg
     9241 cggccagcat acagagaaag tcagctgggc taatgggcca aatcatcata aaaataaaga
     9301 agcggtcaaa acgattgccc ttatctagcc agccgatgta cttgtcgtag gtgcgcttgc
     9361 tgacgacaga ctggacaaag gcagctccgt ataggcgcac tagataaaag ataatggcac
     9421 agccaatcac gatgccgata tagttgtaga tagtcccgat gatgtgcccg tagataaaga
     9481 ccccagccac cgaggtcaag gcccctggaa tgatagggac gacagtctgt aaaatctgta
     9541 aaaagataaa gagaggtgga ccccagatgc ctgcctgctg gataaaggca gagagggttt
     9601 ccttggattg taaaatccca gcctgataag cccaaataca gaaaatcaaa ctcccaaccc
     9661 caccgacaat cgatgagata ttgataactc gctgcagaag gggagaaaca gctttcattt
     9721 gtttatcctg tgacatgtaa actcctcata gatagtatat ttctactata ccatattttg
     9781 gaggagaaag ggggaatgag tcttttttga taaggaatag aaagtaaata gcccttcgag
     9841 acttagaata ggtctgtcaa ctaaaggtta tatgcattct aggtttcgaa taatcgcaat
     9901 tccataaatt taaaagtatt ctaagtttcg aatagcttat ctgagataat tttgaggcat
     9961 tcgcgctttc gaatagtcat tttccctaaa gtttatatgt attctgaagc tagaaagact
    10021 aaaatataaa agtagtaaga gtctctctct gatggacgta atttatggct agtatgaatc
    10081 ctttgaattg ttagttaatt ttaatattaa tcagttctga aataattact aaatatagtt
    10141 agatggtgag ttaattattg ctaaatttca agttcaagtt agtcatccag aagtcttctc
    10201 tgggggactt gtagttcaag cattttttag gatagttgtt aatccacttt tcgataaatg
    10261 cgacttcctt tgtagttgtt ttcttagttc cctgaggtaa ccatctatga atgagcctgt
    10321 tgtgattttc attagatcct atagtgatgt gcataataga tatagcagat tgaaactaga
    10381 atagtataca tctacttcta aaacattgtt agaaatcaat ttgactgtcc tgatcaattt
    10441 gtcctgtttt tatttcattt tactatataa tccttagaaa acatatcgga caagcggttg
    10501 aattccgttc cgtccattag tagataaagg attactcctt cttgaaatga cagatgaact
    10561 tgtttcttat aaaaatgttg tctgaaacta ttagcctttt tccagaagtt ttagaggaag
    10621 aaaactttac gaggaaaaag gagttactca aataacaatt caggattaaa aatagacagt
    10681 tgaggagcgg aaggtataaa ttaagtttgc tactgtataa tggatttatc actaatactc
    10741 ttcgaaaatc tcttcaaacc acgtcagctt cgccttgccg tagatatagt tactgacttc
    10801 gtcagttcta tccacaacct caaaacagtg ttttgagctg acttcgtcag ttttatctgc
    10861 aacctcaaag ctgtactttg agcagcctac ggctagcttc ctagtttgct ctttgctttt
    10921 cattgagtat aaaagtgctc caggccatat tttacacagc aatagtcttc taaaaatgga
    10981 caaaaacatt gtaaaggcta tcaaaaagga gtataatgag tgcaagaaat ttcggaggtg
    11041 aaagatgcta gaagtaagaa gtctagagaa aagttttggc tccaagcaag ttttgtttgg
    11101 tattgacttt caagcgcgac caggtcgtat tttgggacta gtcggaaaaa atggtgctgg
    11161 aaaaacaacg attttccata gtattttgaa attcctagaa tatcagggag aaatcggtct
    11221 ggatggtcag gatattcgtc aggagaccta tgctcggatt ggttatctgc ctgaagaacg
    11281 cagtctcatg cctaaattga cagttcttga acaagttcgc tacttggcga ctctaaaagg
    11341 catggatgcc aaagaagtca aagaaaaact ccctcaatgg atgaagaggt tggaagtgaa
    11401 aggaaagctg acagataaaa tcaagagtct gtcaaaagga aatcagcaga agattcagct
    11461 cattattact ctgattcatg aaccagacct gattatcttg gatgagcctt ttagtggatt
    11521 ggacccagtt aatacagaat tgctcaaaca agtcattttt caggaaaaag agcgcggagc
    11581 aaccattatc ttttctgacc atgtcatgac caatgttgag gaactttgtg acgatattct
    11641 gatgatccga gatggccgtg tggtcttgca cggaccagtt caggatgtcc gcaatcaata
    11701 cgggaaaacg cgtctctttg tttcaagtga acgaagcaag gaagaattgg aaaatcttcc
    11761 tcatgtcaaa caggtgagct tgaccaaaca aggcagttgg aaattgattt tggaggatga
    11821 gagcgctgga agggaactct tcccaatctt gactcaaggt caatatatcg caacatttga
    11881 ccaacaagcg ccaactatcg atgaaatctt taaactagaa tcaggagtgg aagtatgaga
    11941 aatatgtggg ttgtaatcaa ggaaacctat cttcgacatg tcgagtcatg gagtttcttc
    12001 tttatggtga tttcgccgtt cctcttttta ggaatctctg taggaattgg gcatctccaa
    12061 ggttcttcta tggctaaaaa taataaagtg gcagtagtga caacagtgcc atctgtagca
    12121 gaaggactga agaatgtaaa tggtgttaac ttcgactata aagacgaagc aagtgccaaa
    12181 gaagcaatta aagaagaaaa attaaaaggt tatttgacca ttgatcaaga agatagtgtt
    12241 ctaaaggcag tttatcatgg cgaaacatcg cttgaaaatg gaattaaatt tgaggttaca
    12301 ggtacactca atgaactgca aaatcagctt aatcgttcaa ctgcttcctt gtctcaagag
    12361 caggaaaaac gcttagagca gacaattcaa ttcacagaaa agattgatga agccaaggaa
    12421 aataaaaagt ttattcaaac aattgcagca ggtgccttag gattctttct ttatatgatt
    12481 ctgattacct atgcgggtgt aacagctcag gaagttgcca gtgaaaaagg caccaaaatt
    12541 atggaagtcg ttttttctag cataagggca agtcactatt tctatgcgcg gatgatggct
    12601 ctgtttctag tgattttaac gcatattggg atctatgttg taggtggtct ggctgccgtt
    12661 ttgctcttta aagatttgcc attcttggct cagtctggta ttttggatca cttgggagat
    12721 gctatctcac tgaatacctt gctctttatt ttgatcagtc ttttcatgta cgtagtcttg
    12781 gcagcattcc taggatctat ggtttctcgt cctgaggact cagggaaagc cttgtcgcct
    12841 ttgatgattt tgattatggg tggttttttt ggagtgacag ctctaggtgc agctggtgac
    12901 aatctcctct tgaagattgg ttcttatatt ccctttattt cgaccttctt tatgccgttt
    12961 cgaacgatta atggctatgc ggggggagca gaagcatgga tttcacttgc tattacagtg
    13021 atttttgcgg tggtagcaac aggatttatc ggacgcatgt atgctagtct cgttcttcaa
    13081 acggatgatt tagggatttg gaaaaccttt aaacgtgcct tatcttataa atagaagagc
    13141 cttgcgaaag cgaggttttt aaaggtgaaa agggtggaat cacgaaccta atgatgtaca
    13201 cattatgtaa acaggttgct tgaaaactca attgtatagt gaactgaatc tggaatagga
    13261 taatattact tctaaaacat tcttataaat tgatttgaat tccaaaatcc catcgttccg
    13321 ttcttatttc attttgcgat atagtgaaag gaaataagtc agctcacaaa aaacgcataa
    13381 tatcaaggat ttttaacact tgatactatg cgttttctaa ttttaaagac tttttgcctg
    13441 gtctcttttg ttctatgagt atgttacata tctaggtaaa aattatttaa agcaaattaa
    13501 ccttatttct caagatgtag taggttccga gataaaagat agctatgaat atgagttctt
    13561 taacaatggc tatacctgct cccatataga aatggtcatt gagtcctacc agtgaattga
    13621 catagaaatt agaactaaga ttgaagaaaa gttcaataaa tccaatgacg atttggatac
    13681 caatgtaggc tgcaacagcg agtgctgtac ggtattcatt gaaaagctgt ccaatggaaa
    13741 tagccaggta gatgcagagg attcctgaaa tggtatttag taggaaggat atacctgtaa
    13801 gaaagatctg agggagatgt gtttctacaa atgtaatcac ataagaaaga ggaatccatt
    13861 ctggagctgt taaagccaga ataataacag cacttagagc caatacagcg gtgctaatca
    13921 atgaccagat aaaggcaccg attagtttgg ctgtgatgat atggtgttca gaaactggca
    13981 aggtcaaagt cagatagcct tgtcggtcgt agacactacc tttgaagcgt ttaataatca
    14041 agaaaatggt tgaaatcgca agtgtaagca tcaagccacc aaagactgta gctagaaaaa
    14101 gtagcatagt agcctgactt tcttggtaag gtagattttt aaagccttgt gtctgtattc
    14161 cgatgagggc agaaaggact agcacggctg cgtagagggc taaataccac ttgttaacat
    14221 ttttaaattc gtagtgaact aaattccaaa acataaataa tctcctttgc ttaggcctta
    14281 aattcctgac ggaagagttg gtcaatggat tcacctgact cgtagcgaat atcatctaca
    14341 tttccttgac ggacgacttt tccgtctttt aggaagacaa tttcatccaa gattggctcg
    14401 atatcagaaa tcaagtgggt agaaatcaaa acggtagaag ttggtgagta gttgttgata
    14461 atggtattga ggatataagc acgggctgct ggatccaccc caccaatggg ttcatccaaa
    14521 acatagagac gagcatcacg gctcataacc aaaatcagtt gaaccttttc tttgtttcct
    14581 tttgatagtt tcttgagacg actattttca tcaatgccca ggtctgcaag tagatgatga
    14641 gcgcgttcaa gattgaaatc tttatagaag gtcttgaagt aggttagggc ttctttgacc
    14701 ttcatttgct cattgagata ggtcgtatca ggcaaataag ctacaacggc cttggttgct
    14761 gggcttgggt ccatgtcgtt gatgaggaca cgtccttgat ctggttgtaa gaggccatta
    14821 attagtttaa tcagggttgt ttttcctgag ccgtttggcc caagaaggcc gacaattttt
    14881 ccagctggaa tgtcaagaga aacattttca agggctggtg ttgctccata tgatttggat
    14941 acattttcaa atactagtaa tgacataggc ttaaactcct ttaatataat cactgactac
    15001 gcctggtagt tcttcttttt catagccaaa atggatcatg gaggaaacga agtgttccaa
    15061 ttcttcttct gataattgtt tgcgtgactg agcgattagc tccttatcct tagtcacaaa
    15121 tcgtccagtt gttcgcttgc tgtagacaaa tccttctcgt tcaaggtctg ataaggctct
    15181 ttggatggta ttgggattga caccagcctc gctagctagc tccctcacgg ttggaagttg
    15241 ttgattgggt tccagtgtat gggaaacaat ctgaagcttg attttctcca taatctgtaa
    15301 atagatgggt tttttgttgt caaatgtcca ggacatctta gtctcctttc tcttatcctt
    15361 ttgtcttaac taaataatac aacaaaacaa aaaacttgtc aagcaaaaag aagaattgtt
    15421 ttgggaatcg cttaaaaaat ggtataatga aaagaaaacg ataaggaggg aaaggatgcg
    15481 ttgtccaaaa tgtggggcta ccaagtcaag tgttatcgat agtcgccaag cagaagaagg
    15541 gaacaccatt cgtagaagac gtgagtgcga cgaatgccaa caccgtttta caacctacga
    15601 acgagtagaa gaaagaacct tagtggttgt taaaaaagat ggtacacggg aacaattctc
    15661 cagagataaa atctttaatg ggattatccg ctcagcccag aaacgtcctg tgtcaagtga
    15721 tgaaatcaac atggtagtca atcgtatcga acagaaactc cgtggtcgaa atgaaaatga
    15781 aattcaaagt gaggacattg gttcactcgt catggaggag ttggctgaat tggacgagat
    15841 tacctatgta cgttttgcta gtgtctatcg tagttttaag gatgtcagtg agttagagag
    15901 cttgctccaa caaatcaccc agtcctctaa aaagaaaaag gaaagataaa tgaagccaat
    15961 tgaccgtttt tcttatctaa agaataatcg ggtgtcgcaa gatacctcat ctctggtaca
    16021 gtgctacctc ccgattatcg gtcaggaggc actgagcctt tatctttata caatcagttt
    16081 ttgggataat ggtagaaagg aatatctttt ttcaagtatc ctcaatcatc tcaactttgg
    16141 gatggataga ctgataaaat cattgaaaat cttatctgct tttaatctct tgaccctcta
    16201 tcaaaagggg gatgtttatc agctagccct ccatgctcct ctatctagtc aagacttctt
    16261 ggagcatcct gtttatcgca gactcttaga gaaaaagatt ggcgactctg ctgtggagga
    16321 tttgaaagtt gaaagtgctg atggtgaaga aatacctgtc tcactcaatc aagtctttcc
    16381 agaattggca gaactaggca gtcaagaaga ccttggtctc aagaagaaag tggccaatga
    16441 ttttgacttg gaacattttc gccagctgat ggctcgagat ggacttcgtt ttgcggatga
    16501 gcagtccgat gtcttaaacc tctttgctat tgccgaggag aagaaatgga cttggtttga
    16561 aacctatcaa ttggccaagt caacagctgt ttctcaggtt atttcaacca aacgcatgcg
    16621 tgaaaaaatt gctcaaaaac cagtttcctc tgactttaat cctaaggaag caaccattat
    16681 caaggaagct aaaagtaaga ctgccctgca gttcttagca gaaatcaagc aaacacgcaa
    16741 ggggaccatt acccaaacag aaagagaact tttgcaacag atggctggct tgggcttgct
    16801 ggacgaagtc atcaatatca ttctcttgtt gacctttaat aaggtggatt cggcaaacat
    16861 caatgagaaa tatgccatga aggtggctaa tgactatgcc tatcaaaaga tacattcagc
    16921 agaagaggcc gttttacgaa ttcgtgagcg agggcagaaa acaaaaacac aaaaacagaa
    16981 tcagactgcc ccagcaaaaa ccaatattcc taaatggagt aacccagatt ataagaatga
    17041 aaccagcgag gaaactcgtc tggaactaga acgtaagaaa caagaactat tagctcgatt
    17101 agaaaaagga ggagattaga tggaaagtgt cggagacgta ctcaaacgtc aacccagccg
    17161 tttttattat caagatttgg tccagaaaat catgaaggac cctgatgttg cggcttttat
    17221 ccagcaagaa tccttgactc cagaggaatt aaatcgcagt atctccaagt ttaatcagta
    17281 catcaccgag cgtgacaagt ttctccgtgg ggatacggat tatattgcca aaggctacaa
    17341 gccgattttg gttaagaatc atggctatgc agatgtttca tatgaagaaa ctcctgagct
    17401 aatcgcggct gaaaaagaag cggctattaa gaatcgtctc aagctaatca atctaccagc
    17461 cagtctcaaa aaagctagtt tggctcaagt tgatttggat gatttgggac gcttgccagt
    17521 ttttgaaaaa ctattagcct ttgtggagca atatccagct attcgaaaag gtctttactt
    17581 atatggagac tttggtgtgg gtaaaagttt catggtggcg gccttagctc atgatttatc
    17641 agaaaaacgt ggtgtttcat caactctcct ccactatcct agctttgtca ttgatgtcaa
    17701 aaatgctatc agtgatggca atgttaagac cttggtggat gagattaagc tgtctgaggt
    17761 cctgatttta gatgatattg gcgccgagca atcaaccgct tgggtgcgtg acgaaatcct
    17821 gcaggtcatt ctccaatatc ggatgcagga aaatttaccg acctttttca catccaactt
    17881 caactttgaa gatttggaga agcattttgc gaaagtgaaa catggaaatg acgaaacctg
    17941 ggaagccaga cgggtcatgg aacgcatccg ttatttggct gaggagactc gtttagaagg
    18001 agtaaaccgt cgatgacaga aaccattaaa ttgatgaagg ctcatacttc agtgcgcagg
    18061 tttaaagagc aagaaattcc ccaagtagac ttaaatgaga ttttgacagc agcccagatg
    18121 gcatcatctt ggaagaattt ccaatcctac tctgtgattg tggtacgaag tcaagagaag
    18181 aaagatgcct tgtatgaatt ggtacctcaa gaagccattc gccagtctgc tgttttcctt
    18241 ctctttgtcg gagatttgaa ccgagcagaa aagggagccc gacttcatac cgacaccttc
    18301 caaccccaag gtgtggaagg tctcttgatt agttcggtcg atgcagctct tgctggacaa
    18361 aacgccttgt tggcagctga aagcttgggc tatggtggtg tgattatcgg tttggttcga
    18421 tacaagtctg aagaagtggc agagctcttt aacctacctg actacaccta ttctgtcttt
    18481 gggatggcac tgggtgtgcc aaatcaacat catgatatga aaccgagact gccactagag
    18541 aatgttgtct ttgaggaaga ataccaagaa cagtcaactg aggcaatcca agcttatgac
    18601 cgtgttcagg ctgactatgc tggggcgcgt gcgaccacaa gctggagtca gcgcctagca
    18661 gaacagtttg gtcaagctga accaagctca actagaaaaa atcttgaaca gaagaaatta
    18721 ttgtagaaag tgagaaatta tggccctacc aactattgcc attgtaggac gtcccaatgt
    18781 tgggaaatca accctattta atcggatcgc tggtgagcga atctccattg tagaagatgt
    18841 cgaaggagtg acacgtgacc gtatttatgc aacgggtgag tggctcaatc gttcttttag
    18901 catgattgat acaggaggaa ttgatgatgt cgatgctcct ttcatggaac aaatcaagca
    18961 ccaggcagaa attgccatgg aagaagcaga tgttatcgtc tttgtcgtgt ccggtaagga
    19021 aggaattacc gatgcagacg aatacgtagc ccgtaagctt tataagaccc acaaaccagt
    19081 tatcctcgca gtcaacaagg tggacaaccc tgagatgaga aatgatatct atgatttcta
    19141 tgctctcggt ttgggtgaac cattgcctat ctcatctgtc catggaatcg gtacagggga
    19201 tgtgctagat gcgatcgtag aaaatcttcc aaatgaatat gaggaagaaa atccagatgt
    19261 cattaagttt agcttgattg gtcgtcctaa cgttggaaaa tcaagcttga tcaatgctat
    19321 cttgggagaa gaccgtgtta ttgctagtcc tgttgctgga acaactcgtg atgccattga
    19381 tacccacttt acagatacag atggtcaaga gtttaccatg attgatacgg ctggtatgcg
    19441 taagtctggt aaggtttatg aaaatactga gaaatactct gttatgcgtg ccatgcgtgc
    19501 tattgaccgt tcagatgtgg tcttgatggt catcaatgcg gaagaaggca ttcgtgagta
    19561 cgacaagcgt atcgcaggat ttgcccatga agctggtaaa gggatgatta tcgtggtcaa
    19621 caagtgggat acgcttgaaa aagataacca cactatgaaa aactgggaag aagatatccg
    19681 tgagcagttc caatacctgc cttacgcacc gattatcttt gtatcagctt taaccaagca
    19741 acgtctccac aaacttcctg agatgattaa gcaaatcagc gaaagtcaaa atacacgtat
    19801 tccatcagct gtcttgaacg atgtcatcat ggatgccatt gccatcaacc caacaccgac
    19861 agacaaagga aaacgtctca agattttcta tgcgacccaa gtggcaacca aaccaccaac
    19921 ctttgtcatc tttgtcaatg aagaagaact catgcacttt tcttacctgc gtttcttgga
    19981 aaatcaaatc cgcaaggcct ttgtttttga gggaacaccg attcatctca tcgcaagaaa
    20041 acgcaaataa aaaagtagaa tctggaatga cagttccgga tttttttgat ataataaaat
    20101 aatagaaaac gctatcaaaa gaaggagggt gatgtcggtg atggaacatt tgtttaaatt
    20161 cttactttta gcaccgtact tttattttga taactggatt gagaaggcca acagaaatag
    20221 taagtttttt ccaatttttt attattttta ctggttttac atccccttct attctctttt
    20281 tagccttgct tggacagttg tttcagttct gtttttcaat accgtcttga gaaatgtgac
    20341 agatatcaag ttatggggca tttggtttct ttttattctg ctagctattg gtatgaattg
    20401 gttaacttat tcctgtttca aagaaatgtt tcgcttgaga caggaactag ggaagtctaa
    20461 gggtggaagg cattgattta tatcggtttc tatttgtagg aggtggctta tggtacctct
    20521 aaaatcattt attacacgct attccaaggt ttatattggt aataacattt aatagaacga
    20581 aactaaagaa aacaatttaa aagaggaggt ttgtgatgga atacttgttt aaaatgataa
    20641 tcttattacc ctgtttttac tttttcagct ggattgaaaa ggcaaacaga gatagtaaga
    20701 ttttcccaat tttttactat ttttactgga tttacatcac cctctatgct ctttttagcc
    20761 ttgcttggac agttttttca gttctgtttt tcaatatcgt cttgagaaat ttgacagata
    20821 tcaagttatg gggtatttgg ctattattac tacttatcgc ttttgctagt gactggttag
    20881 actatatctg tttcaaaaaa atgcttgact tgagacggga actagggaag tctaaaggcg
    20941 gaaggcattg atttatactc ttcgaaaatc tcttcaaacc acgtcaacgt cgccttggat
    21001 tatatatgta actgacttcg tcagtcttat ctacaacctc aaagcagtgc tttgagcaac
    21061 ttgcggctag tttcctagtt tgctctttga ttttcattga gtattatatt actttctatt
    21121 tgtaggaggt ggcttatgaa gattcctctc ttaactttgg caaggcataa atttgtttat
    21181 gtcttgctta ctttgctttt tcttgctttg gtttatcgtg atgttttgat gacttatttc
    21241 ttttttgata ttcatgcgcc cgatctagct aaattcgatg gacaagcaat taaaaatgac
    21301 ttattaaaat cagcattaga ttttcgtatt ctccagttca atctaggttt ttatcaatca
    21361 tttattattc caatcatcat tgttttgcta ggttttcaat atattgagct gaaaaataaa
    21421 gttttacgat tgagtattgg aagagaagtg agctatcaag ggttaaaaag aaagttgact
    21481 ttgcaagttg caagtatccc ttgtttgata tatttagtga ctgtgctgat aattgcaatt
    21541 ataacctatt tctttgggac tttttctcct cttgaatgga attctctatt ttctgatggg
    21601 agtggtttac aaagactcct agatggagag ataaaaagct atttgttctt tacttgtgtc
    21661 ctactaatcg gtattttcat caatgcaatc tattttttac aaatagttga ttatgtgggg
    21721 aatgtgactc gttcggcaat cacctatttg atgtttcttt ggcttggttc tatgctgctc
    21781 tatagtgcct tgccttacta tatggttcct atgacgagtt tgatgcaagc tagctatggg
    21841 gatgtaagtt tgatgaaact ctttactcct tatatccttt atgttgtccc ttatatggta
    21901 cttaaaaaat atgaagataa tgtttaagaa ttttaacaat atttggctaa agagaaagat
    21961 cgttttacta cttcgtatag ttctgatgat gattttgata aactatctat tgtcaacagc
    22021 ggttcaaaag caggatgctg ttatcttttt caagagagaa ttgatttcaa ttttttccta
    22081 taatgactat tctgaagcga atttagaaat ccccaaactc ttgttaaacc tttcgctttt
    22141 catggtagga tggctctctg tcattttact tgaaagtgat ttggcagacc attaccatca
    22201 cttgattcgc tatcaatcaa gctccttttt cgattataca aggaaacgat tggttgtcat
    22261 ttctaaattt tttactcaag atttgtttgt ctggtttctt ggtttacttc cgctaggaat
    22321 tcatttcaaa acagtcgcac ttttcttttt acttgctcag ttaatgatgt tgtacttact
    22381 actgtcttat ctgatagcac tgattagtgc gggcgctggt ttttcttttt ttctctattt
    22441 tttggcattt gtgggacaag aatggatgat ggatcatatt gtaacagtgt atttagtact
    22501 cttaagctta ttagttatgt tgattgttag tcgcttggaa gagaaattta agaaaggata
    22561 aacgatgaga cttgaaatta taaatggaca gaaaatttat gggaaaagac ctattttaaa
    22621 tcagttgaat ttggtgtttc aatcaggaaa aatttatgga cttaaaggtg ataatggatc
    22681 tggcaagacg gttcttttaa agatacttgc tggttatatt aagcttgaca aaggaaaagt
    22741 tcttcaagat ggtaaagttt acggggtaaa aaatcattat attcaggatg caggaatttt
    22801 aattgaaaaa gtcgagtttt tatctcattt atccctgaga gaaaatttgg aactgttaag
    22861 gtatttttca tctaaagtta cggaaaaaag aattgcctat tggattcaat actatgattt
    22921 acaggaattt gaagacgttg aataccgtca tttatccttg ggaacaaagc aaaaaatggc
    22981 cttgattcaa gcctttattt cctctccttc tatactcttt ctcgatgaac ctatgaatgc
    23041 tttggatgag aagagtgtga ggttaaccaa acaggtcatt ttatcttacc tgaaaaaaga
    23101 aaatggtctg gttatcctga cgtcgcacat atcggaagat atttcagacc tttgtacaga
    23161 tgtattagtt gtcgaaaatg gacatataca atatgtaaag gatatacaat cctaggagat
    23221 ggcttatggc acatctaaaa tcatttatta cacgctattc caaggtttat attggtttag
    23281 ttctgctgat ctggctgtct ttcttcttta tcccttggga tagagcgatt ctgggggtaa
    23341 ggattgacat cttcatcatg cagaaaatct tgctagcttt tggaattctg tccattctca
    23401 tggccttgct gtccaagaaa gtcagtctct ttgtttttgg actgatttgc tgtctttctc
    23461 tttggattaa cttatttatc acatttgcca ttttgccgat ttttggcaat taaacagtca
    23521 taaaagtcgg agaggttagc ttgaaaacta acctcttttt ccttttcaaa atggggattc
    23581 ttccttgaaa ataatcagta attgtgctaa aattaaagga acattctaaa atattcggaa
    23641 tttaaagtaa ggaaaaacat ggctaatatt ttaaaaacaa ttatcgaaaa tgataaagga
    23701 gaaatccgtc gtctggaaaa gatggctgac aaggttttca aatacgaaga ccaaatggct
    23761 actttgactg acgaccaact aaaagcaaaa acagttgaat ttaaggaacg ttatcaaaat
    23821 ggagaatcac tggattcatt gctttacgaa gcatttgcgg ttgtccgtga aggtgccaaa
    23881 cgtgtcctag gtctcttccc ttataaggtt caggtcatgg gggggattgt tcttcaccat
    23941 ggtgacgtgc cagagatgcg tacaggggaa gggaaaacct tgactgcgac catgccggta
    24001 tacctcaatg ccctttcagg taaaggggtt cacgtagtta cggttaatga atacctgtca
    24061 gaacgtgacg cgactgagat gggtgaattg tactcttggc ttggtttgtc agtagggatt
    24121 aacttggcta ccaaatctcc aatggagaaa aaagaagcct atgagtgtga tattacttac
    24181 tcaactaact cagaaatcgg atttgactac cttcgtgaca acatggtcgt tcgcgccgaa
    24241 aacatggtac aacgtccgct taactatgcc ttggtcgatg aggttgactc tatcttgatt
    24301 gacgaggctc gtacaccttt gattgtatca ggtgccaatg cggttgaaac cagtcagttg
    24361 tatcacatgg cagaccacta tgtaaaatct ttgaacaaag atgactacat catcgatgtg
    24421 cagtctaaga ctattggttt gtctgattca gggattgaca gggctgaaag ctacttcaaa
    24481 cttgaaaacc tctatgacat cgaaaacgtg gctttgactc actttatcga taacgccctt
    24541 cgtgccaact acatcatgct tctcgatatt gactatgtgg tgagcgaaga gcaagaaatc
    24601 ttgattgtcg accaatttac aggtcgtacc atggaaggtc gtcgttattc tgatggattg
    24661 caccaagcta ttgaagccaa agaaggtgtg ccaatccagg atgaaaccaa gacatctgcc
    24721 tcaatcacgt accaaaacct tttccgtatg tacaagaaat tgtctggtat gacgggtaca
    24781 ggtaagactg aggaagaaga attccgtgaa atctacaaca ttcgtgttat tccaatccca
    24841 acaaaccgtc ctgttcaacg tattgaccac tcagaccttc tttatgcaag tatcgaatct
    24901 aagtttaaag cggttgtcga agacgttaag gctcgttacc aaaagggtca acctgtcttg
    24961 gttggtacag tagcggttga aactagtgac tacatttcta agaaattggt tgcagctggt
    25021 gttcctcacg aagtcttgaa tgccaaaaac cactatagag aagcccaaat catcatgaat
    25081 gctggtcaac gtggtgccgt taccatcgca accaacatgg cgggtcgtgg taccgacatc
    25141 aagcttggtg aaggtgttcg tgaacttgga ggactttgtg ttattggtac agaacgtcat
    25201 gaaagtcgtc gtatcgataa ccagcttcgt ggacgttcag gtcgtcaagg agatccaggt
    25261 gagtcacaat tctacctatc tcttgaagat gatttgatga aacgttttgg ttctgaacgc
    25321 ttgaagggaa tctttgaacg tttgaacatg tctgaagagg cgattgagtc tcgcatgttg
    25381 acgcgtcagg ttgaagcagc tcagaaacgt gtcgaaggaa ataactacga tacccgtaaa
    25441 caagtccttc aatacgatga tgtcatgcgt gaacaacgtg agattatcta tgctcaacgt
    25501 tacgatgtca tcactgcaga tcgtgacttg gcacctgaaa ttcaggctat gatcaaacgc
    25561 acgattgaac gtgtcgttga tggtcatgcg cgtgccaaac aagatgaaaa actagaggca
    25621 attttgaact ttgctaagta caacttgctt cctgaagatt ctattacgat ggaagacttg
    25681 tcaggcttgt ctgataaggc catcaaggaa gagcttttcc aacgtgcctt gaaggtttac
    25741 gatagtcagg tttcaaaact acgcgatgaa gaagcagtta aagaattcca aaaagttttg
    25801 attctacgag tggtggataa caagtggaca gatcatatcg atgcccttga tcaattgcgt
    25861 aacgcggttg gacttcgtgg ctatgctcag aacaaccctg ttgttgagta tcaggcagaa
    25921 ggtttccgta tgtttaatga tatgattggt tcgattgagt ttgatgtgac acgcttgatg
    25981 atgaaagcac aaattcatga acaagaaaga ccacaggcag aacgtcatat cagtacaaca
    26041 gcgactcgca atatcgctgc tcaccaagca agtatgccag aagatttgga tttgagccag
    26101 attggacgca atgaactttg cccatgtggt tctggtaaga aatttaaaaa ctgtcacggt
    26161 aaaagacaat aaaatgagat agtttagagg cggatatctt gtgaaaagta aatttttact
    26221 gggtatccgt ttgctttata aggagatgag ttatggtatt tacagcaaaa agctctaaaa
    26281 taaatataga agaagttcgt gccttgtcaa aattagaagg tcaggctttg gagaggaaat
    26341 cacagcgcga tcaagagcta gaagccatta tacgtggaga agatcagcga attctcttgg
    26401 taatcgggcc atgctcatct gacaacgaag aagctgtcct tgaatacgct aagcgtttgg
    26461 cagtcctaca agaagaagtg gcagatcgta tctttatggt tatgcgtgtt tatactgcca
    26521 aaccccgtac caacggagat ggctataagg gcttgattca ccagcctaac gcgacagaag
    26581 cgcctagtct tatcaatgga atcaaagccg ttcgccatct tcactatcgt gtcatcacag
    26641 aaacagggat gacaactgct gatgaaatgc tttatcctga aaaccttccg cttgtagatg
    26701 atttgatttc ttacatggca gttggtgccc gttcagttga agaccagcaa caccgctttg
    26761 tggcaagtgg ggcaggattt tctactggtt ttaaaaatcc aacctctgga aatctcaatg
    26821 tcatgtttaa tgggatttat gctgctcaaa acaaacaaag tttccttttc ttaggaaaag
    26881 aagtagaaac aactgggaac ccgctttcac acgctattct tcgtggtgct cttaatgagt
    26941 atggaaaaaa tattcccaac tactattatg acaatttaat tgataccatt gcccaatatg
    27001 agaaaatggg cttggaaaat ccttttatca tcattgatac caatcatgac aattctggta
    27061 agcagtatat tgaacagatc cgaattgtcc gccagacctt gattaaccgt gcttggaatg
    27121 aaaaaattaa gcagttcgtt cgtggtttta tgattgagtc ttatctggaa gatggtcgac
    27181 aaaatgagcc agaagtattt ggcaagtcta tcacagaccc ttgcctgggt tgggataaca
    27241 cagaagctct tgtcagagaa atttacaaaa cgttaggaga ataagatggc atttattgaa
    27301 aaaggtcaag aaatcgatat ggaagtcatc aaggctgaaa cccaattgtc tgcggaagcc
    27361 ttgagactca aggaaagccg tgacagggaa ttggcagata ttatttcagg ggaagatgac
    27421 cgtattctct tggtgattgg tccttgctct tctgataatg aagaggcggt cttggaatat
    27481 gctcgccgtt tatccgcctt gcaaaagaag gtagcggaca agattttcat ggtcatgcgc
    27541 gtgtatactg ctaagcctcg taccaatgga gacggctata aaggattggt tcaccagcca
    27601 gatacttcta aggctccaag cctgattaac ggtttgcagg ctgtgcgcca gttgcattac
    27661 cgcgtgatta cagagactgg tttgacaacg gcagatgaga tgctttatcc gtcaaatctg
    27721 atcttggtgg atgacttggt cagctaccat gccgttggag ctcgttctgt ggaagaccaa
    27781 gagcaccgct ttgtggcttc tgggattgat gcaccagtag ggatgaaaaa tccaacctca
    27841 ggaaatttgg gtgttatgtt taacgccatc tatgctgctc aaaacaagca aaccttcctt
    27901 tatcatgggc aggaagttga gacatcaggt aatcctttgg cccatgttat cctccgtgga
    27961 gcagtcaacg agtatggcaa ttatatgccg aattactact atgaaaacct actccaagcc
    28021 attgaacgct atgaaaccat gggacttgaa aatcctttta tcctcattga caccaaccat
    28081 gataactcag gcaagcaata tatggagcag attcgaattg ttcgccagac cttgcagaat
    28141 cgtgattgga atgagaaaat taaaaagacg gttcgaggat ttatgattga atcttaccta
    28201 gcagatggtc gtcaaaacca accagagatc tttggttgct ctattactga cccttgccta
    28261 ggttgggaaa atacagaggc cttggtagaa gagatttatg ttaccttgac aaaataagtg
    28321 aaaaggatgg agttggggaa tctcaactcc ttttgatgag aatgatagtt ggacacggaa
    28381 ttgacatcga agaattggct tcgatagaaa gcgcagttac acgacatgaa ggatttgcta
    28441 agcgtgtact gaccgctcag gaaatggagc gcttcaccag tctcaaagga cgcaggcaaa
    28501 tagaatattt agctggtcgc tggtcggcta aggaggcctt ttccaaggct atgggaacgg
    28561 gcattagcaa gctcggtttt caggatttgg aagtattgaa caatgaacgt ggggcgcctt
    28621 attttagtca ggcaccattt tcaggaaaga tttggctgtc tatcagccac accgatcagt
    28681 ttgtgacagc cagtgtcatt ttggaggaaa atcatgaaag ctagtccaca tagaccaacc
    28741 aaggctctga ttcatctggg agctattcga caaaatattc agcaaatggg ggctcatatc
    28801 cctcaaggaa cgctcaagtt ggctgtggtt aaggccaatg cttatggtca tggagctgtt
    28861 gccgttgcca aggcaattca agatgatgtt gatggctttt gcgtttccaa tatcgatgaa
    28921 gccattgaac tcagacaagc tggactcagc aagccaatcc tcattttagg agtttctgaa
    28981 atcgaagctg ttgctctagc taaagaatat gacttcacct tgacagtggc tggactggag
    29041 tggattcaag cactcttaga taaggaagtg gacctaactg gattgacagt ccacctcaag
    29101 attgattcag ggatgggacg gattggtttt agagaggcaa gtgaggttga gcaggctcaa
    29161 gatttgctcc aacaacacgg tgttcgtgtt gaaggaatct ttacccactt tgctactgct
    29221 gatgaggaat cagatgacta ttttaatgcc cagttagaac ggtttaaaac tattttagct
    29281 agtatgaagg aagttccaga gctggttcat gctagcaatt ctgcaacgac tctttggcat
    29341 gtagagacta ttttcaatgc ggttcgtatg ggagatgcca tgtatggtct caatccaagt
    29401 ggagcggtct tggctttgcc ttatgatttg ataccggcct tgaccttgga gtctgctctg
    29461 gttcatatca agacagttcc agctggtgct tgcatgggct atggagcaac ttatcaaacg
    29521 gatagcgagc aagtcatcgc gaccgtgcca atcgggtatg cagatggatg gacaagagac
    29581 atgcaaaatt tctctgtctt ggtagatggc caagcttgcc caattgtcgg cagggtttcg
    29641 atggaccaaa tcactattcg attgcctaag ccttacccac tcggaaccaa ggtaaccttg
    29701 attggctcca atggggataa ggaaatcact gcaactcagg tagcgaccta ccgcgtaacc
    29761 attaactatg aggtggtttg cctcctcagc gaccgtattc cgagagaata ttactagaaa
    29821 agaaaggagt ggagcatgaa tctacatcaa cccttgcatg tcttgcctgg tgtgggacca
    29881 aagtcagcag aaaaatacgc caaactagga attgaaaact tgcaagatct cttgctctac
    29941 tttcctttcc gttatgaaga cttcaaaatc aagcaggtgc tggagctgga agacggtgag
    30001 aaggcagttc tttctggtca ggtagtgact cctgctagtg tccagtatta tggtttcaag
    30061 cgcaatcgcc tgcgttttag tctcaagcag ggagaggtcg tttttgcggt gaatttcttt
    30121 aaccagccct atctggctga taaaatagag ttgggagcaa cccttgctgt ctttggaaaa
    30181 tgggaccgcg ctaaggctag tctgactggg atgaaggttc tggctcaggt agaagatgac
    30241 ctccagcctg tctatcgtct ggctcaggga atcagtcagg ccagtctggt taaggtcatc
    30301 aagacggctt ttgatcaggg actggacctc ttgatagaag aaaatctgcc ccagtcttta
    30361 ctagacaaat acaaactcat gtcccgttgt caggcagtcc gagctatgca ttttccaaag
    30421 gatttggcag aatacaagca ggctcttcgc cgtatcaagt ttgaggaact cttttatttc
    30481 caaatgcagc tgcagatgct caagtctgaa aatagagttc agggaagtgg tctggttctg
    30541 aattggtctc aggaaaaagt gacagcagtt aaagtaagtc ttccttttgc cctgacccaa
    30601 gctcaggaaa agagtttgca ggaaatttta actgatatga agtccgacca ccacatgaat
    30661 cgtctcctac aaggggatgt ggggagtgga aaaacggtag tcgctggctt ggccatgttt
    30721 gcggcagtga cagcaggtta tcaggctgcc ctaatggtac caacagaaat cctcgcagag
    30781 caacactttg agagtttaca gaaccttttt cccaatttga aactggctct cttgacaggt
    30841 tccttgaaag ctgcagaaaa gagagaggtc ttggagacca ttgccaaggg tgaggctgat
    30901 ttgattatcg gaactcacgc tctgatacaa gatggggtgg agtatgctcg tcttggtttg
    30961 attattatcg atgagcagca ccgttttggt gtagggcaaa ggcgtatttt acgggaaaaa
    31021 ggtgacaatc cagatgtcct catgatgacg gcgactccca ttccacggac gcttgccatc
    31081 acagcctttg gagatatgga tgtttccatt atcgaccaga tgccagcagg tcggaagcct
    31141 attgtgacgc gctggatcaa acatgagcaa ctacctcagg tcttgacttg gttagagggg
    31201 gaaattcaaa aaggttccca agcctatgtc atctctcctt tgattgaaga atcagaagct
    31261 ctagatttga aaaatgccat tgccttatca gaggagttga cgactcattt tgcaggcaag
    31321 gcagaggtgg ctcttctaca tggtaggatg aagagtgacg aaaaagacca gatcatgcag
    31381 gatttcaagg agagaaagac ggatattctg gtttcgacga cggttattga ggttggggtc
    31441 aacgttccca atgcgactgt catgattatc atggatgccg atcgcttcgg tctcagtcaa
    31501 cttcaccagc ttagaggtcg tgtcggtcgg ggggacaagc agtcctacgc tgttctcgtt
    31561 gccaatccca agacggattc tgggaaagac cgcatgcgta tcatgacaga aacgaccaat
    31621 ggatttgtcc ttgcggagga agatttgaaa atgcgtggtt ctggtgagat ttttggaacc
    31681 agacagtcag gacttccaga gttccaagtg gctgatatta tcgaagattt tccgatttta
    31741 gaagaagcaa gaaaggttgc tagctacatt agttctatag aagcttggca agaagatcca
    31801 gagtggcgca tgattgccct tcatctggaa aagaaagaac atctggatta agctttctct
    31861 aaggaaaact taagctagtt tttaggtttg gctcttatac taaagtcatc aaaaagaaac
    31921 gaggactctc atatgacagt aacgattaaa gtaaattacc aaaccacttt ccaaaagaag
    31981 gaagcaaaaa actagtataa acagaagaga gagcgaaatg ctctttttcg tttctaaaac
    32041 tactttcagc ccatcatcct aaaagtaaag aatctaaatt cactttctat ttatccttct
    32101 ttcttgcatt gattacatag atatgctaca gttgtggtaa cgattacaaa ataaaaggag
    32161 catgctatga aaaatccagc tttgctagaa gaaattaaga cctatagagg aagggatgag
    32221 gttccggaag actttgatgc tttctgggat ggggaagtga aaaatgtttc cacgcttcca
    32281 tcctaccact tggaggaaag agatttccac attcctcaag tcaagtgcta tgagttaaca
    32341 tttgaaggaa gcaaggaagg aaaggtctat gcacgcattg ttcttccaaa gagtgaggag
    32401 aaggttccac taatcttcca ttttcatggt tatatgggac gtggctggga ctgggccgac
    32461 atgctgggct tcaccgtagc tggttacggt gttgtttcca tggatgtgcg gggccagtca
    32521 ggttactcac aagacggctt gcgttctcct ttaggaaata ccgtgaaggg gcatattatc
    32581 cgtggtgcta tggaaggtcg ggaccacctc ttttataagg atgtttatct ggatatttac
    32641 cagttggtcg aaattgttgc tagtctgtct caggttgatg agaagcgtct ttctagctat
    32701 ggtgcctcac aaggaggggc tctagctcta gttgcagcag cgctcaatcc tcgaattcag
    32761 aaaacagttg ccatttatcc cttcttgtca gacttcagac gggtgattga gattggtaat
    32821 actagcgagg cttacgacga acttttccgt tatttcaagt ttcacgaccc cttccatgaa
    32881 acagaggagg aaatcatggc gacccttgcc tatatcgatg tcaaaaatct tgcccatcgt
    32941 atccaaggtg aggttaagat gattacgggc ttggacgacg atgtttgcta tcccattacc
    33001 cagtttgcga tttataatcg tctgacctgc gataaaacct atcgcatcat gcctgagtat
    33061 gctcacgaag ccatgaatgt atttgtcaat gaccaagtct acaactggct ctgtggaagt
    33121 gagattcctt ttaaatatct aaaataagga gtcgactcta agcacaaaat cttaaaaatt
    33181 acaaacacgc atagtatcag gggattaaaa aaacttgata ctatgcgttt tatcatggaa
    33241 atatagtaaa atgaaacaag aataggacaa aacgatcagg acagtcaaat cgatttctaa
    33301 caatgtttta gaagcaaatg tgtactattc tagtttcaat ctattatatt tatagaattt
    33361 tttgttgcta gatttgtcaa attgcttaaa ataatttttt tcagaaagca aaagccgata
    33421 cctatcgagt agggtagttc ttgctatcgt caggcttgtc tgtaggtgtt aatacttttc
    33481 aaaaatctct ttaaaccacg tcagcttcgc cttgccgtat atatgttact gacttcgtca
    33541 gttctatctg ccacctcaaa acggtgtttt gagctgactt tgtcagtctt atctacaacc
    33601 tcaaaacagt gttttgagca tcatgcggct agcttcttag tttgctcttt gattttcatt
    33661 gagtataaaa acagatgagt ttctgttttc tttttatgga ctataaatgt tcagctgaaa
    33721 ctactttcaa ggacattatt atataaaaga attttttgaa actaaaatct actatattac
    33781 actatattga aagcgtttta aaaatgaggt ataataaatt tactaacgct tataaaaagt
    33841 gatagaatct atctttatgt atatttaaag atagattgct gtaaaaatag tagtagctat
    33901 gcgaaataac agatagagag aagggattga agcttagaaa aggggaataa tatgatattt
    33961 aaggcattca agacaaaaaa gcagagaaaa agacaagttg aactactttt gacagttttt
    34021 ttcgacagtt ttctgattga tttatttctt cacttatttg ggattgtccc ctttaagctg
    34081 gataagattc tgattgtgag cttgattata tttcccatta tttctacaag tatttatgct
    34141 tatgaaaagc tatttgaaaa agtgttcgat aaggattgag caggaagtat ggtataaata
    34201 gcataagctg atgtccatca tttgcttata aagagatatt ttagtttaat tgcagcggtg
    34261 tcctggtaga taaactagat tggcaggagt ctgattggag aaaggagagg ggaaaattgg
    34321 caccaatttg agatagtttg tttagttcat ttttgtcatt taaatgaact gtagtaaaag
    34381 aaagttaata aaagacaaac taagtgcatt ttctggagta aatgtcttat ttcagaaatc
    34441 gggatataga tatagagagg atcagtatga atcggagtgt tcaagaacgt aagtgtcgtt
    34501 atagcattag gaaactatcg gtaggagcgg tttctatgat tgtaggagca gtggtatttg
    34561 gaacgtctcc tgttttagct caagaagggg caagtgagca acctctggca aatgaaactc
    34621 aactttcggg ggagagctca accctaactg atacagaaaa gagccagcct tcttcagaga
    34681 ctgaactttc tggcaataag caagaacaag aaaggaaaga taagcaagaa gaaaaaattc
    34741 caagagatta ctatgcacga gatttggaaa atgtcgaaac agtgatagaa aaagaagatg
    34801 ttgaaaccaa tgcttcaaat ggtcagagag ttgatttatc aagtgaacta gataaactaa
    34861 agaaacttga aaacgcaaca gttcacatgg agtttaagcc agatgccaag gctccagcat
    34921 tctataatct cttttctgtg tcaagtgcta ctaaaaaaga tgagtacttc actatggcag
    34981 tttacaataa tactgctact ctagaggggc gtggttcgga tgggaaacag ttttacaata
    35041 attacaacga tgcaccctta aaagttaaac caggtcagtg gaattctgtg actttcacag
    35101 ttgaaaaacc gacagcagaa ttgccaaatg gtcgagttcg cctgtatgtt aatggtgttt
    35161 tatctcgaac aagtctgaaa tctggcaatt tcattaaaga tatgccagat gtaacgcatg
    35221 tgcaaatcgg agcaaccaag cgtgccaaca atacggtttg ggggtcaaat ctacagattc
    35281 ggaatctcac tgtgtataat cgtgctttaa caccagaaga ggtacaaaaa cgtagtcaac
    35341 tttttaaacg ctcagattta gaaaaaaaac tacctgaagg agcggcttta acagagaaaa
    35401 cggacatatt cgaaagcggg cgtaacggta aaccaaataa agatggaatc aagagttatc
    35461 gtattccagc acttctcaag acagataaag gaactttgat cgcaggtgca gatgaacgcc
    35521 gtctccattc gagtgactgg ggtgatatcg gtatggtcat cagacgtagt gaagataatg
    35581 gtaaaacttg gggtaaccga gtaaccatta ccaacttacg tgacaatcca aaagcttctg
    35641 acccatcgat cggttcacca gtgaatatcg atatggtgtt ggttcaagat cctgaaacca
    35701 aacgaatctt ttctatctat gacatgttcc cagaagggaa gggaatcttt ggaatgtctt
    35761 cacaaaaaga agaagcctac aaaaaaatcg atggaaaaac ctatcaaatc ctctatcgtg
    35821 aaggagaaaa gggagcttat accattcgag aaaatggtac tgtctataca ccagatggta
    35881 aggcgacaga ctatcgcgtt gttgtagatc ctgttaaacc agcctatagc gacaagggtg
    35941 atctatacaa gggtaaccaa ttactaggca atatctactt cacaacaaac aaaacttctc
    36001 catttagaat tgccaaggat agctatctat ggatgtccta cagtgatgac gacgggaaga
    36061 catggtcagc gcctcaagat attactccga tggtcaaagc cgattggatg aaattcttgg
    36121 gtgtaggtcc tggaacagga attgtacttc ggaatgggcc tcacaaggga cggattttga
    36181 taccggttta tacgactaat aatgtatctc acttaaatgg ctcgcaatct tctcgtgtca
    36241 tctattcaga tgatcatgga aaaacttggc atgctggaga agcggtcaac gataaccgtc
    36301 aggtagacgg tcaaaagatc cactcttcta cgatgaacaa tagacgtgcg caaaatacag
    36361 aatcaacggt ggtacaacta aacaatggag atgttaaact ctttatgcgt ggtttgactg
    36421 gagatcttca ggttgctaca agtaaagacg gaggagtgac ttgggagaag gatatcaaac
    36481 gttatccaca ggttaaagat gtctatgttc aaatgtctgc tatccatacg atgcataatg
    36541 gaaaagaata cattatcctc agcaatgcag gtggaccgaa tcgtgaaaat gggatggtcc
    36601 acttggcacg tgtcgaagaa aatggtgagt tgacttggct caaacacaat ccaattcaaa
    36661 aaggagagtt tgcctataat tcgctccaag aattaggaaa tggggagtat ggcatcttgt
    36721 atgaacatac tgaaaaagga caaaatgcct ataccctatc atttagaaaa tttaattggg
    36781 aatttttgag caaagatctg atttctccta ccgaagcgaa agtgaagcga actagagaga
    36841 tgggcaaagg agagatgggc aaaggagtta ttggcttgga gtttgactca gaagtattgg
    36901 tcaacaaggc tccaaccctt caattggcaa atggtaaaac agcgactttc ctaacccagt
    36961 atgatagcaa aaccttgttg tttgcagtag ataaggaaga tatcggacag gaaattattg
    37021 gtatagctaa aggaagcatc gaaagtatgc ataatcttcc tgtaaatcta gcaggtgcca
    37081 gagttcctgg cggagtaaat ggtagcaaag cagcggtgca tgaagttcca gaatttacag
    37141 ggggagttaa tggtacagag ccagctgttc atgaaatcgc agagtataag ggatctgatt
    37201 cgcttgtaac tcttactaca aaagaagatt atacttacaa agctcctctt gctcagcagg
    37261 cacttcctga aacaggaaac aaggagagtg acctcctagc ttcactagga ctaacagctt
    37321 tcttccttgg tctgtttacg ctagggaaaa agagagaaca ataagagaag aattctaaac
    37381 atttgatttt gtaaaaatag aaggagatag caggttttca agcctgctat ctttttttga
    37441 tgacattcag gctgatacga aatcataaga ggtctgaaac tactttcaga gtagtctgtt
    37501 ctataaaata tagtagattg aaataagatg tgaacaactc tatcaggaaa gtcaaattaa
    37561 tttatagaaa aattttagca gtcaaggtgt actgttatag attcaatata ttatgtgact
    37621 attaaccttc tcttctccta aaattgactt tcttgttttc ttatcttgtc cactcgaaac
    37681 aagtattgta agaatttgat tatttttgaa agtactttta atatacttga tatagttaaa
    37741 aaagatttga aactaaattc caaattagaa aaagacttga aatactaaaa aaaaaaagta
    37801 tactctaatt gaaaacggta acaaaactaa tttagagaat gaaatataga gtatttctct
    37861 cttaaaagtt tttggtgaaa cgagatgtag aaaggagatt tagccaaaga gtctattagt
    37921 gctagaataa tagattagaa ttattttaga aaaacgaagt gagcagctta taaattcaag
    37981 tccccaaata gattcatact agtatctttt gcaaaaaata aagggcgact tccttcatga
    38041 atatcaattt catctataag gaaggtagct aattgaacta acttatttat tctgtttgtc
    38101 gctagaaaaa tcagacctcc ttgtgaagat tgaggagata ctgaatgaaa atcaaagaag
    38161 aaactagcaa gctagtagca gattgcccaa aacaccgcct tgaggttgta gataagactg
    38221 acctatataa tccaaggtga agcgactgtg gtttgaagag attttcaaag agtataggct
    38281 agagagtagt gtttttatgt ccttctagta gaaaatgcta gacagaagaa tggggaactt
    38341 ggataggaaa aatagattga gaaaggaggt tagaagagat gattattaca aaaattagcc
    38401 atttaggaac ttatgtggga gtaaatccac attttgcaac attaatagat tttctagaaa
    38461 aaacaggact agaaaattta acagaaggtt cgattgctat cgatggtaat cgattgtttg
    38521 ggaattgctt tacttatcta gcagatggtc aagcaggggc tttctttgaa acacaccaaa
    38581 aatatttgga tattcattta gttttggaaa acgaagaagc catggctgtt acatcgccgg
    38641 aaaatgtaag cgttacccaa gaatatgatg aagagaaaga tattgaatta tacacaggga
    38701 aagtggaaca gttggttcag ttgagagctg gcgaatgcct catcactttt ccagaagatt
    38761 tacatcaacc caaggttcgt ataaatgatg aacctgtgaa aaaagttgtc tttaaagttg
    38821 cgatttctta atgtagaaag agaagaacga tgaaaaaaat gagaaagttt ttatgtctag
    38881 ctggaattgc gctagcggct gttgccttgg tagcttgttc aggaaaaaaa gaagctacaa
    38941 ctagtactga accaccaaca gaattatctg gtgagattac aatgtggcac tcctttactc
    39001 aaggaccccg tttagaaagt attcaaaaat cagcagatgc tttcatgcaa aagcatccaa
    39061 aaacgaaaat caagattgaa acattttctt ggaatgactt ctatactaaa tggactacag
    39121 gtttagcaaa tggaaatgtg ccagatatca gtacagctct tcctaaccaa gtaatggaaa
    39181 tggtcaactc agatgctttg gttccgctaa atgattctat caagcgtatt ggacaagata
    39241 aatttaacga aactgcctta aatgaagcaa aaatcggaga tgattactac tctgttcctc
    39301 tttattcaca tgcacaagtc atgtgggtta gaacagattt gttaaaagaa cataatattg
    39361 aggttcctaa aacttgggat caactctatg aagcttctaa aaaattgaaa gaagctggag
    39421 tttatggctt gtctgttccg tttggaacaa atgacttaat ggcaacacgt ttcttgaact
    39481 tctacgtacg tagtggtgga ggaagcctct taacaaaaga tcttaaagca gacttgacaa
    39541 gccaacttgc tcaagatggt attaaatact gggttaaatt gtataaagaa atctcacctc
    39601 aagattcttt gaactttaat gtccttcaac aagctacctt gttctatcaa ggaaaaacag
    39661 catttgactt taactctggc ttccatatcg gaggaattaa tgccaacagt cctcaattga
    39721 ttgattcgat tgatgcttat cctattccaa aaatcaaaga gtctgataaa gaccaaggaa
    39781 ttgaaacctc aaacattcca atggttgttt ggaaaaattc aaaacatcca gaagttgcta
    39841 aagcattctt agaagcactt tataatgaag aagactacgt taaattcctt gattcaactc
    39901 cagtaggtat gttgccaact attaagggga ttagcgattc tgcagcctat aaagaaaatg
    39961 aaactcgtaa gaagtttaaa catgctgaag aagtaattac tgaagctgtt aaaaaaggta
    40021 ctgctattgg ttatgaaaat ggaccaagtg tacaagctgg tatgttgact aaccaacaca
    40081 ttattgaaca aatgttccaa gatatcatta caaatggaac agatcctatg aaagcagcaa
    40141 aagaagcaga aaaacaatta aacgatttat ttgaggctgt tcagtagatg taaaagacta
    40201 gaaaataggt gggctagtga gctgaaaagc tctagcccaa tcttgtaaaa gaagggagaa
    40261 ggagaatggt taaagaacgt aatttaactc gctggatatt tgttttgcca gctatgatta
    40321 tcgtaggatt actctttgtt tatccgtttt tctcgagtat tttttatagc tttaccaata
    40381 agcatttgat tatgcctaat tataaatttg ttggtttggc taactataaa gctgtgctat
    40441 cagatcccaa cttctttaat gcgttcttta attcaattaa gtggaccgtt ttctcattag
    40501 ttggtcaagt tttagtaggg tttgtattgg ctttagctct tcacagagta cgccacttca
    40561 agaaattata taggacctta ttgattgttc cttgggcatt tcctaccatc gttattgcct
    40621 tttcttggca gtggattcta aacggggttt atggctactt acctaatcta atcgtaaaat
    40681 taggtttaat ggaacataca cctgcatttt tgacagatag tacatgggca ttcctatgtt
    40741 tggtgtttat caacatttgg tttggagcac caatgattat ggttaatgtg ctttcagctt
    40801 tgcaaacagt accagaagaa caatttgagg ctgctaagat agatggtgct tcaagttggc
    40861 aggtgttcaa gtttatcgtc tttccacata ttaaagtggt tgtaggactt ctagttgttt
    40921 tgagaactgt atggatcttt aataactttg acattatcta cctcattact ggtggtggac
    40981 cagccaatgc tacaacgacg cttccaattt ttgcttacaa cctgggctgg ggaactaaat
    41041 tgttgggtcg tgcttcagca gttacagtat tgctctttat cttcttggtg gcgatttgct
    41101 ttatctactt tgctatcatc agtaagtggg aaaaggaggg tagaaaataa tgaagaagaa
    41161 atccagtatt tatttagata ttctctcaca tgtactttta gttggtgcga ccatcgttgc
    41221 aattttccca ttggtatgga ttatcatatc ttctgtcaaa gggaaagggg aattaactca
    41281 gtatccaaca cgattttggc ctgaacagtt tacattagat tatttcactc atgttatcaa
    41341 cgatttgcac ttcattgata acattcgaaa cagtttaatc attgccttgg ctacaaccct
    41401 cattgcgatt attatttctg ctatggcagc ctatggtatt gttcgattct ttcctaaatt
    41461 gggagcaatc atgtcgagac tactcgtcat tacctacatt ttcccaccaa ttttgttagc
    41521 aattccctat tcaattgcca ttgctaaagt tgggttaaca aatagtttat ttggcttgat
    41581 gatggtttat ctatctttta gtgttccata tgcagtttgg ctcttagttg gatttttcca
    41641 aacagttcca attggaattg aagaagcggc tagaattgat ggtgcaaata aatttgttac
    41701 gttttataaa gttgtgctac cgattgtagc accaggtatt gtagcaacag ctatttatac
    41761 atttatcaat gcttggaatg aattcctgta tgccttgatt ttgattaaca atacaggaaa
    41821 gatgacagta gcagtagccc ttcgttcact taatggttca gaaatactag actggggaga
    41881 tatgatggca gcgtctgtta ttgtagttct tccatcaatt attttcttct ctatcatcca
    41941 aaataagatt gcaagtggat tatcagaagg atctgtgaag tagacgaaag aaggaaaaaa
    42001 atgaataaaa gaggtcttta ttcaaaacta ggaatttctg ttgtaggcat tagtctttta
    42061 atgggagtcc ccactttgat tcatgcgaat gaattaaact atggtcaact gtccatatct
    42121 cctatttttc aaggaggctc atatcaactg aacaataaga gtatagatat cagccctttg
    42181 ttattagata aattgtctgg agagagtcag acagtagtaa tgaaatttaa agcagatgaa
    42241 ccaaactctc ttcaagcttt gtttggccta tctaatagta aagcaggctt taaaaataat
    42301 tacttttcaa ttttcatgag agattctggt gagataggtg tagaaataag agacgcccaa
    42361 aagggaataa attatttatt ttccagacca gcttcattat ggggaaaaca taaaggacag
    42421 gcagttgaaa atacactagt atttgtatct gattctaaag ataaaacata cacaatgtat
    42481 gttaatggaa tagaagtgtt ctctgaaaca gttgatacat ttttgccaat ttcaaatata
    42541 aatggtatag ataaggcaac actaggagct gttaatcgtg aaggcaagga acattacctc
    42601 gcaaaaagaa gtattgatga aatcagtcta tttaacaaag caattagtga tcaggaagtt
    42661 tcaaatattc ccttgtcaaa tccatttcag ttaattttcc aatcaggaga ttctactcaa
    42721 gctaactatt ttagaatacc gacactatat acattaagta gtggaagagt tctatcaagt
    42781 attgatgcac gttatggtgg gactcatgat tctaaaagta agattaatat tgccacttct
    42841 tatagtgatg ataatgggaa aacgtggagt gagccaattt ttgctatgaa gtttaatgac
    42901 tatgaggagc agttagttta ctggccacga gataataaat taaagaatag tcaaattagt
    42961 ggaagtgctt cattcataga ttcatccatt gttgaagata aaaaatctgg gaaaacgata
    43021 ttactagctg atgttatgcc tgcgggtatt ggaaataata atgcaaataa agccgactca
    43081 ggttttaaag aaataaatgg tcattattat ttaaaactaa agaagaatgg agataacgat
    43141 ttccgttata cagttagaga aaatggtgtc gtttatgatg aaacaactaa taaacctaca
    43201 aattatacta taaatgataa gtatgaagtt ttggagggag gaaagtcttt aacagtcgaa
    43261 caatattcgg ttgattttga tagtggctct ttaagagaaa ggcataatgg aaaacaggtt
    43321 cctatgaatg ttttctacaa agattcgtta tttaaagtga ctcctactaa ttatatagca
    43381 atgacaacta gtcagaatag agaagagagt tgggaacaat ttaagttgtt gcctccgttc
    43441 ttaggagaaa aacataatgg aacttacttg tgtcctggac aaggtttagc attaaaatca
    43501 agtaacagat tgatttttgc aacatatact agtggagaac taacctatct catttctgat
    43561 gatagtggtc aaacatggaa gaaatcctca gcttcaattc cgtttaaaaa tgcaacagca
    43621 gaagcacaaa tggttgaact gagagatggt gtgattagaa cattctttag aaccactaca
    43681 ggtaagatag cttatatgac tagtagagat tctggagaaa catggtcgga agtttcgtat
    43741 attgatggaa tccaacaaac ttcatatggc acacaagtat ctgcaattaa atactctcaa
    43801 ttaattgatg gaaaagaagc agtcattttg agtacaccaa attctagaag tggccgtaag
    43861 ggaggtcaat tagttgtcgg tttagtcaat aaagaagatg atagtattga ttggaaatac
    43921 cactatgata ttgatttgcc ttcgtatggt tatgcctatt ctgcgattac agaattgcca
    43981 aatcatcaca taggtgtact gtttgaaaaa tatgattcgt ggtcgagaaa tgaattgcat
    44041 ttaagcaatg tagttcagta tatagatttg gaaattaatg atttaacaaa ataaaggaga
    44101 aaaacatggt taaatacggt gttgttggag cagggtattt tggagctgaa ttggctcgct
    44161 acatgcaaaa gaatgatgga gcagagatta ctcttctcta tgatccagat aatgcagagg
    44221 cgattgcaga agaattggga gcaaaagtag caagttcctt agatgagttg gtttctagcg
    44281 atgaagtaga ttgtgttatc gtcgcaactc caaataatct tcataaggaa ccggttatta
    44341 aggctgcaca gcatggtaaa aatgttttct gtgaaaaacc aattgcgctt tcttatcaag
    44401 attgtcgcga gatggtagat gcgtgtaaag aaaacaatgt aacctttatg gcaggacata
    44461 ttatgaattt ctttaatggt gttcatcatg caaaagaact cattaatcaa ggagttatcg
    44521 gagacgttct atattgtcat acagctcgta atggttggga agaacaacaa ccgtcagtgt
    44581 catggaaaaa aattcgtgaa aaatcaggtg gtcacttgta tcaccacatc catgaattgg
    44641 attgcgttca attccttatg gggggcatgc ctgaaactgt aaccatgaca ggtggaaatg
    44701 tggcccatga aggtgaacat ttcggtgatg aagatgatat gatttttgtc aatatggaat
    44761 tttctaataa gcgttttgcc ttgttagaat ggggttcagc ttatcgttgg ggtgaacatt
    44821 atgtcttaat ccaaggaagc aaaggtgcca tccgcttaga cttattcaac tgtaaaggaa
    44881 ctcttaagct agatgggcaa gaaagctatt tcttgattca cgaatcgcaa gaagaagatg
    44941 atgatcggac tcgtatctat catagtacag agatggatgg agcaattgct tatggtaaac
    45001 caggtaaacg tactccatta tggctatcat ctgtcattga taaagaaatg cgctatctgc
    45061 atgagattat ggaaggagct ccagtatcag aagaatttgc aaaacttttg acaggtgaag
    45121 ctgccctaga agcaattgct actgcagatg cttgtaccca gtctatgttt gaagatcgca
    45181 aagtaaaatt gtcagaaatt gtaaaataaa ttttggtatt ctcctattta taggtcgact
    45241 tgctcctctg aaagtacttt tagaggagct gtttgacttt gctagttttt gaaactgaaa
    45301 tctattatac tacaaactat tgaaagcgtt ttaattttaa ggtataataa tctcatagaa
    45361 ataaagaaaa ggaggaaaga ggatgccaca gattagcaaa gaagccttga ttgagcaaat
    45421 caaagatgga atcatcgttt cttgtcaggc tcttcctcat gaaccgcttt atacagaagc
    45481 gggaggggtg attcccttgc tggtcaaagc ggctgagcaa ggtggagcag tcggtatccg
    45541 agcaaacagt gttcgcgata tcaaggaaat taaggaagtc actaaacttc caatcattgg
    45601 gattatcaaa cgtgattatc cacctcagga acccttcatc acggctacta tgaaagaagt
    45661 tgatgaattg gcagaactgg acatcgaggt gattgctctg gattgtacca agcgtgaacg
    45721 ctacgatggt ttggaaattc aagagttcat tcgtcaggtt aaggagaaat atcctaatca
    45781 gcttttgatg gctgatacta gtatcttcga agaagggcta gcagctgtag aagcaggaat
    45841 tgactttgtc ggaacaacct tatcaggcta cacatcctac agtccaaaag tagacggtcc
    45901 agattttgaa ttgattaaga aactctgtga tgccggtgta gatgtcattg cagaaggaaa
    45961 aattcataca ccagaacaag ccaaacaaat ccttgaatat ggagtgcgag gcatcgttgt
    46021 tggtggcgcc attactagac caaaagagat tacagaacgc ttcgttgcta gtcttaaata
    46081 agatgtgagg gggagtttta tgtttaaagt tttacaaaaa gttggaaaag cttttatgtt
    46141 acctatagct atacttcctg cagcaggtct acttttgggg attggtggtg cactttcaaa
    46201 cccaaccacg atagcaactt atccaatact agacaatagt atttttcaat caatattcca
    46261 agtaatgagc tctgcaggag aggttgtatt cagtaatttg tcactacttc tctgtgtggg
    46321 attatgtatt ggcttagcga aacgagataa aggaaccgct gcgttagcag gagtaactgg
    46381 ttacttagtt atgactgcaa cgatcaaagc tttagtaaaa ctttttatgg cagaaggatc
    46441 tgcaattgat actggagtta ttggagcatt agttgtcgga atagttgccg tatatttgca
    46501 caaccgatat aacaatattc aattaccttc cgctttagga ttctttggag gttcacgctt
    46561 cgttcctatt gttacatcgt tctcttctat cttgattggc tttgtcttct ttgttatttg
    46621 gccacctttc caacaacttc ttgtttctac aggtggatat atttctcagg cgggtccaat
    46681 tggaactttt ctatatggat ttttaatgag actttctgga gcagtaggct tacatcatat
    46741 aatttaccct atgttttggt atactgaact tggtggtgtt gaaactgttg caggacaaac
    46801 agtggttgga gctcaaaaaa tattttttgc tcaattagcc gatttggccc attctggatt
    46861 atttacagaa ggaacaaggt tttttgcagg tcgtttctca acaatgatgt tcggtttacc
    46921 ggctgcctgt ttagcgatgt accatagtgt tcctaaaaat cgtcgtaaaa aatacgcggg
    46981 tttgtttttg ggagttgctt taacatcttt tattaccggt attacagaac caattgaatt
    47041 tatgtttcta ttcgttagtc cggttctata tgttgttcac gcattccttg atggtgttag
    47101 cttctttatt gcagacgtct taaatatttc aataggaaac acattttcag gaggtgtaat
    47161 cgatttcact ttatttggaa ttttgcaggg gaacgctaag acgaattggg ttcttcagat
    47221 tccatttgga cttatttgga gtgttttgta ttatattatt tttagatggt tcattactca
    47281 attcaacgtt ctaacgccag ggcgaggaga agaagtagat tctaaagaaa tttctgaatc
    47341 cgcagattca acttcaaata ctgcagatta tttaaaacag gatagcctac aaattatcag
    47401 agccttgggt ggatcaaata atatagaaga tgtagatgct tgtgtgacac gtttacgtgt
    47461 agctgtaaaa gaagttaatc aagttgataa agcactttta aaacaaattg gtgcagttga
    47521 tgtcttagaa gtgaagggtg gcattcaagc aatatatgga gcaaaagcaa tcttatataa
    47581 aaatagtatt aatgaaattt taggtgtaga tgattaagta cttactgact taataaaaaa
    47641 cagaggagag tgatggatga gtaggatgaa atgaaatcgc atacaagaaa taaagaactc
    47701 attatccaag ttggatacgc ttattacata ggagaataca aatgaaattt agaaaattag
    47761 cttgtacagt acttgcgggt gctgcggttc ttggtcttgc tgcttgtggc aattctggcg
    47821 gaagtaaaga tgctgccaaa tcaggtggtg acggtgccaa aacagaaatc acttggtggg
    47881 cattcccagt atttacccaa gaaaaaactg gtgacggtgt tggaacttat gaaaaatcaa
    47941 tcatcgaagc gtttgaaaaa gcaaacccag atataaaagt gaaattggaa accatcgact
    48001 tcaagtcagg tcctgaaaaa atcacaacag ccatcgaagc aggaacagct ccagacgtac
    48061 tctttgatgc accaggacgt atcatccaat acggtaaaaa cggtaaattg gctgagttga
    48121 acgacctctt cacagatgaa tttgttaaag atgtcaacaa tgaaaacatc gtacaagcaa
    48181 gtaaagctgg agacaaggct tatatgtatc cgattagttc tgccccattc tacatggcaa
    48241 tgaacaagaa aatgttagaa gatgctggag tagcaaacct tgtaaaagaa ggttggacaa
    48301 ctgatgattt tgaaaaagta ttgaaagcac ttaaagacaa gggttacaca ccaggttcat
    48361 tgttcagttc tggtcaaggg ggagaccaag gaacacgtgc ctttatctct aacctttata
    48421 gcggttctgt aacagatgaa aaagttagca aatatacaac tgatgatcct aaattcgtca
    48481 aaggtcttga aaaagcaact agctggatta aagacaattt gatcaataat ggttcacaat
    48541 ttgacggtgg ggcagatatc caaaactttg ccaacggtca aacatcttac acaatccttt
    48601 gggcaccagc tcaaaatggt atccaagcta aacttttaga agcaagtaag gtagaagtgg
    48661 tagaagtacc attcccatca gacgaaggta agccagctct tgaatacctt gtaaacggat
    48721 ttgcagtatt caacaataaa gacgacaaga aagtcgctgc atctaagaaa ttcatccagt
    48781 ttatcgcaga tgacaaagag tggggaccta aagacgtagt tcgtacaggt gctttcccag
    48841 tccgtacttc atttggaaaa ctttatgaag acaaacgcat ggaaacaatc agcggctgga
    48901 ctcaatacta ctcaccatac tacaacacta ttgatggttt tgctgaaatg agaacacttt
    48961 ggttcccaat gttgcaatct gtatcaaatg gtgacgaaaa accagcggat gctttgaaag
    49021 ccttcactga aaaagcaaac gaaacaatca aaaaagctat gaaacaatag tccttagtta
    49081 ttctataaaa agtagttttt taaagaacct aagagtgtat accccctttt ccctctacac
    49141 agatagtgta agaaaagggg gcttttgttt aaaatgtaag aaactgtcac gaaattaaaa
    49201 tgaagttctt acataagcga atcataaaaa atttcatttt gattttaaaa cagttcaaga
    49261 aagtcaaaaa attattctat ttgaaagaga ggtgccgact gtgaaagtca ataaaatccg
    49321 tatgcgggaa acagtgattt cctacgcttt cctagcacca gtattattct tctttgtcat
    49381 ctttgtgttg gctccgatgg tgatgggctt cattacaagt ttctttaact actcaatgac
    49441 taaatttgag tttgtaggct tggataacta tatccgtatg tttaaagatc ctgtctttac
    49501 aaaatctctg attaacacag ttattttggt tattggatct gtaccagttg ttgttctatt
    49561 ctcactcttt gtagcatctc agacctatca tcaaaatgtc attgccagat ccttctaccg
    49621 tttcgtcttc ttccttcctg ttgtaacggg tagtgttgcc gtgacagttg tttggaaatg
    49681 gatttatgac ccactatcag ggattctaaa ctttgtcctt aagtccagcc acatcatcag
    49741 ccaaaacatt tcttggttgg gagataaaaa ctgggcattg atggcgatta tgattattct
    49801 cttgaccact tcagttggtc agcccatcat cctttatatc gctgccatgg ggaatattga
    49861 caattcactg gttgaagcgg cgcgtgttga tggtgcaact gagtttcaag ttttttggaa
    49921 gattaaatgg ccaagccttc ttccaacaac tctttatatt gcaatcatca caacaattaa
    49981 ctcattccag tgtttcgcct tgattcagct tttgacatct ggtggtccaa actactcaac
    50041 aagtaccttg atgtactacc tttacgaaaa agccttccaa ttgacagaat acggctatgc
    50101 caacacaatt ggtgtcttct tggcagtcat gattgctatc gtaagctttg ttcaatttaa
    50161 agtacttgga aacgacgtag aatactaaag aaaggagaca gctatgcaat ctacagaaaa
    50221 aaaaccatta acagccttta ctgttatttc aacaatcatt ttgctcttgt tgactgtgct
    50281 gttcatcttt ccattctact ggattttgac aggggcattc aaatcacaac ctgatacaat
    50341 tgttattcct cctcagtggt tccctaaaat gccaaccatg gaaaacttcc aacaactcat
    50401 ggtgcagaac cctgccttgc aatggatgtg gaactcagta tttatctcat tggtaaccat
    50461 gttcttagtt tgtgcaacct catctctagc aggttatgta ttggctaaaa aacgtttcta
    50521 tggtcaacgc attctatttg ctatctttat cgctgctatg gcgcttccaa aacaagttgt
    50581 ccttgtacca ttggtacgta tcgtcaactt catgggaatc cacgatactc tctgggcagt
    50641 tatcttgcct ttgattggat ggccattcgg tgtcttcctc atgaaacaat ttagtgaaaa
    50701 tattcctaca gagttgcttg aatcagctaa aatcgacggt tgtggtgaga ttcgtacctt
    50761 ctggagtgta gccttcccga ttgtgaaacc agggtttgca gcccttgcaa tctttacctt
    50821 catcaatact tggaatgact acttcatgca gttggtaatg ttgacttcac gtaacaattt
    50881 gaccatctca cttggggttg cgaccatgca ggctgaaatg gcaaccaact atggtttgat
    50941 tatggcagga gctgcccttg ctgctgttcc aatcgtcaca gtcttccttg tcttccaaaa
    51001 atccttcaca cagggtatta ctatgggagc ggtcaaagga taatactctg cgaaaatcga
    51061 atgcaaacta cgtcagcttc accttgccat acttaagtat tgcctgcggt tagcttccta
    51121 gtttgttctt caattttcat tgagtatagg aaaatcaatc tatcaagata cagaagtata
    51181 ttttatagat ttagagaata tagaagttat aagtgtctac aaaatggagg gtatgcagtt
    51241 actttatgaa gttttgtcag acacttatca acttaagaat gattttagtt aattatcaga
    51301 aacgaaggaa agagtatgat ttttgacgat ttgaaaaaca tcacctttta caaagggatt
    51361 catcccaatt tagacaaagc tatcgactac ctctaccaac atcgtaaaga ttcattcgaa
    51421 ttaggaaagt atgagattga tggagataag gtctttctag ttgttcagga aaatgtcctc
    51481 aatcaagttg agaataatca atttgaacac cataagaact atgcagattt gcatttgctg
    51541 atagaagggc atgaatattc gagctacggt tcacgtatca aagacgaggc agtagcattc
    51601 gacgaagcga ctgacattgg ctttgttcat tgtcatgaac actacccact cttgttgggt
    51661 tatcataatt ttgcgatttt cttcccaggt gagccacatc agccaactgg ctatgcaggt
    51721 atggaagaaa aggttcgaaa atatctcttt aaaattttga ttgattaaaa ataggatgaa
    51781 ttgttttttt gtaaagcttt gacaatactc taccatgaaa ttgatcttta tgaggtagag
    51841 aaatgagaat aaaatattta aaaattggta tcttctaagc atgctgcaag agctagtttc
    51901 ttagatggac aggaaattac agttgatgag atgtcctgga taattaatgg cattgtgaat
    51961 gcattgattg gtagatacat aaaattaggt acttatgcag ctaagtatgg tattggtata
    52021 gcacgctcga tcttaagtag ggcagctgca actgcagcag caagagtagg attactgacc
    52081 aagatttctg gatggatttt acgagtagct gtgaatgtag ctgatgtata tggtaatttc
    52141 gccaacaata ttgctgcagc ttgggatgca tatgataaaa ttcctaacaa tggtcgtata
    52201 aacttttaaa atacgagaat gaaagcactt tgtatttttt tattgaatat gttagcttgg
    52261 acagtgcttg caatgataat tcgtggaggg ctagatggat ttgataggca tacttggagt
    52321 actattttaa ttgcttcgct gttcggggta tatgattata agcccataga taaaaataga
    52381 aaaaagtcca aaagaaaaaa gaaaaaatag atttgttcat ggtagggact tatgaaagct
    52441 ttactgacaa aaaagaaaac agtttacaaa gaaaaatgat ggaggagcaa acatggcaca
    52501 aaaaggagta agccttatca aggcagcatt tgatacagat aactttctca tgcgttttag
    52561 tgagaaggtc ttggacatcg tgacagccaa tcttcttttt gtcgtctctt gtttacccat
    52621 cgtgacgatt ggagtggcta aaatcagcct ctacgagacc atgttcgaag ttaagaagag
    52681 cagacgggtg cctgttttta aaatctatct aagatctttc aagcaaaatc tgaaactagg
    52741 tcttcagctg ggtttaatgg agttaggaat tgtgtttctt accctttcag atctctatct
    52801 tttctggggt caaacagctc tgcccttcca attgctgaaa gccatttgtt taggtattct
    52861 gatttttctt actatcgtga tgctggctag ttaccctatc gcggcacgtt atgacctatc
    52921 ttggaaagaa attcttcaaa aaggattgat gttggctagt tttaactttc cttggttctt
    52981 cctcatgtta gccattcttg tcctcattgt gatggttctt tatctgtccg ccttcagtct
    53041 actcttaggt ggctcagtct tcctactttt tgggtttgga ctattggtct ttatccagac
    53101 tggattgatg gagaaaattt tcgcaaaata ccaataggag ctttatttct gaaactactt
    53161 tcaaaggctc caaacgctat tctataagcg agaaactaaa atctaagtgt ctataagata
    53221 ttgaaagcct tttcggtaaa gtgtatacta aagaagtaaa gaaaaatctg ctttagcaga
    53281 aaataaaaat aataggagaa aatctatgtc agatttgaaa aaatacgaag gtgtcattcc
    53341 agccttctac gcatgttatg atgagcaagg agaagtaagt ccagagcgta cgcgtgcctt
    53401 ggttcaatac ttcattgata aaggtgttca aggtctttat gtcaatggtt cttctggtga
    53461 atgtatctac caaagcgttg aagatcgcaa gttgattttg gaagaagtca tggcggtagc
    53521 taaaggtaaa ttgaccatta ttgcccatgt tgcctgcaac aatactaaag acagtatgga
    53581 acttgctcgc catgctgaaa gcttgggagt agatgctatt gcaacgattc caccaattta
    53641 tttccgcttg ccagaatact cagttgccaa atactggaac gatatcagtt ctgcagctcc
    53701 aaacacagac tacgtgattt acaacattcc tcaattggca ggggttgctt tgactccaag
    53761 cctttacaca gaaatgttga aaaatcctcg tgttatcggt gtgaagaact cttctatgcc
    53821 agttcaagat atccaaacct ttgtcagcct tggtggggaa gaccatatcg tctttaacgg
    53881 tccagatgaa cagttcctag gtggtcgcct catgggtgcc aaagctggta tcggtggtac
    53941 ttatggtgct atgccagaac tcttcttgaa actcaaccaa ttgattgcgg ataaagattt
    54001 agaaacagcg cgtgagttac agtatgctat caacgctatc attggtaaat tgactgctac
    54061 acatggaaat atgtacggtg tcatcaaaga agttttgaag atcaatgaag gcttgaatat
    54121 tggttctgtt cgttcaccat tgacaccagt gactgaagaa gatcgtccag ttgtagaagc
    54181 ggctgctgcc ttgattcgtg aaaccaagga gagcttcctc taatctaaaa ggaggtattt
    54241 atgacatact acgttgcaat tgatatcggt ggaaccaaca tcaagtatgg tttggttgat
    54301 caagaggggc aacttcttga atcgcatgaa atgccaactg aggcgcataa gggtggacct
    54361 catatcttac aaaagaccaa agatatcgta gctagttatt tagaaaaagg cccagtagca
    54421 ggtgttgcca tatcttctgc tgggatggtg gatccggata agggtgagat tttctatgct
    54481 gggccgcaaa tccctaacta cgcaggcacc cagttcaaaa aggaaatcga agaaagcttt
    54541 actattcctt gtgagattga aaatgatgtc aactgtgcag gtcttgctga ggcagtatct
    54601 ggttcaggca agggagcaag tgtgacactt tgcttgacca ttggaaccgg tatcggtggt
    54661 tgcttgatta tggataggaa agtcttccat ggttttagca attcagcctg tgaagtcggg
    54721 tatatgcata tgcaggatgg agcttttcaa gacttggctt ctacaacagc tttagtgaaa
    54781 tatgtagctg aagcccatgg agaagatgtt gatcagtgga atggccgtag aattttcaaa
    54841 gaagccactg aaggaaacaa aatctgcatg gaaggtattg accgtatggt tgactatcta
    54901 ggaaaaggtc tggcaaatat ttgctacgtt gccaatccag aagtggttat tcttggtggt
    54961 ggtatcatgg ggcaagaggc tatcctcaaa cctaagatcc gcacagcctt gaaagaggct
    55021 ttggtaccaa gtttagcaga aaaaacacga ttagaatttg cccatcacca aaatacagca
    55081 gggatgttgg gtgcatatta tcattttaag acaaaacaat cctagtttgg ctcagccaaa
    55141 ctaggatttt cttacacgtt tttgtctacg atagccgttg agttttttat tttcccagta
    55201 gctattaaag attttttcct tgctttcgcg attgatttcc aaaaagtagg cataaatcaa
    55261 atcgataaag aagagcatag gaagttgagc ggatattcgt tggatatagg agggttggct
    55321 gtgggtggct acaagaacag tctctgtata ggtctggcta tctttattgg gaacacttgt
    55381 aaagagtaca gtctttgccc ccatctcctt ggcatctaat agactatcta aaatagaagg
    55441 agttgagcct gaaagtgaga agcccagtac tagacaattt tcatccatga tgctggttgt
    55501 ccaggcaaag ccgtcttggt ctgtcaaagc ttcgcagacc acacctagtc gcataaaacg
    55561 taatttcatt tcacgggcga cgaggccaga actccctgtt ccaaagaagt agatacgctc
    55621 agcatcttcg attagctggg caattcgctc tagttggatt tcgtcaatca agtcttgtgt
    55681 ttgttccctc atattgctat aacttctgag gactcgtttg gtcagtggac tgtgcttgga
    55741 gactcggttg gcttgatttt ctgcctgatg ttggtattgg aaaataaatt ctcggtagcc
    55801 agtaaagcca cactttttag caaagcgggt caaagcagct tgagaaatat gtaatttttg
    55861 ggtgacttgt tgagaagata aatcatctgt aatcgtttca gcttgcaaaa aatagcgagc
    55921 gatttcttgc tctaggtctg tcatttcttc aaaatgtgaa tcaatgatag ttgcgatatc
    55981 tggtttgtcc atagggaaag ctcctttaca tgagtcatac tggaagacta gatcagggaa
    56041 tagtcacact tcattataac acataatata aggatagata aataaaaacg catctctgtt
    56101 ttaaaaacga aaaaatcgaa aaagcttctc tcttttccat aattttctac tcaaattgtg
    56161 gtacaattaa gagtaagatt ttaagttaga aatgagactg atttgtatga gaaaatttaa
    56221 cagccattcg attccgattc ggcttaattt attgttttca atcgtcattt tactctttat
    56281 gaccattatt ggtcgtttgt tgtatatgca ggttttgaac aaggattttt acgaaaaaaa
    56341 gctagcctca gctagtcaga ccaagattac aagcagttca gcccgtgggg aaatttatga
    56401 tgctagtgga aaacctttgg tagaaaatac gttaaagcag gttgtttcct ttacgcgtag
    56461 caataaaatg acggctacag acttaaaaga aacagctaaa aagttactga cttatgtgag
    56521 catcagttct ccaaatttga caaaacgcca gctggcggat tactatttgg ctgatcctga
    56581 aatctataaa aaaacagtgg aagctctccc aagcgagaaa cgcttggatt cagatggcaa
    56641 tcgtctatcc gaatcagaac tgtataacaa tgcggtcgat agtgtccaaa caagtcaact
    56701 aaactataca gaggatgaaa agaaagaaat ctatcttttt agtcagttaa atgctgttgg
    56761 aaactttgcg acaggaacca ttgctacaga tcctctaaat gattctcagg tggctgttat
    56821 tgcctctatt tcaaaggaga tgcctggcat tagtatttct acttcttggg atagaaaggt
    56881 tttggaaact tccctttctt ctatagttgg gagtgtatcc agtgaaaaag ctggtctccc
    56941 agcggaagaa gcagaagcct atcttaaaaa aggctattct ctaaatgacc gtgtaggaac
    57001 ctcctatttg gaaaagcaat atgaagagac cttacaagga aaacgatcgg taaaagaaat
    57061 ccatctggat aaatatggca atatggaaag cgtggataca attgaggaag gtagtaaggg
    57121 aaacaatatc aaactgacca ttgatttggc cttccaagat agcgtggatg ctttgctgaa
    57181 aagttatttc aattctgagc tagaaaatgg tggagccaag tattctgaag gtgtctatgc
    57241 agtcgccctt aacccaaaaa caggtgcggt tttgtctatg tcagggatta aacatgactt
    57301 gaaaacggga gagttgacgc ctgattcctt gggaacggta accaatgtct ttgttccagg
    57361 ttcggttgtc aaggcggcga ccatcagctc aggttgggaa aatggagtct tgtcaggaaa
    57421 ccagaccttg acagaccagt ccattgtctt ccaaggttca gctcccatca attcttggta
    57481 tactcaggct tacggttcat tccctatcac agcggtccaa gctctggagt attcatcaaa
    57541 tacctatatg gtccaaacag ccttaggtct tatggggcaa acctatcaac ccaatatgtt
    57601 tgtcggcacc agcaatctag agtctgctat ggagaaactg cgttcaacct ttggcgaata
    57661 tggcttgggt actgcgacag gaattgacct accagatgaa tctactggat ttgttcccaa
    57721 agagtatagc tttgctaatt acattactaa tgcctttggg cagtttgata actatacgcc
    57781 gatgcagttg gctcagtatg tagcaactat tgcaaataat ggtgttcgtg tggctcctcg
    57841 tattgttgaa ggcatttatg gtaataatga taagggagga ctgggtgact tgattcagca
    57901 actgcaaccg acagagataa ataaggtcaa tatatccgac tccgatatga gcatcttgca
    57961 ccaaggtttt tatcaggttg cccatggtac tagtggattg acaactggac gtgccttttc
    58021 aaatggtgcc ttggtatcca ttagcggaaa aacaggtaca gccgaaagct atgtggcaga
    58081 tggtcagcaa gcaaccaata ccaatgcggt ggcctatgcc ccatctgata atccccaaat
    58141 cgctgtcgca gtggtctttc ctcataatac caatctaaca aatggtgtag gaccttccat
    58201 tgcgcgtgac attatcaatc tgtatcaaaa ataccatcca atgaactaga aaggaaatta
    58261 tgctttatcc aacacctatt gccaagttga ttgacagtta ttctaagtta ccaggtatcg
    58321 ggattaagac ggctacgcgt ctggcctttt atacgattgg gatgtctgct gatgatgtca
    58381 atgaatttgc aaaaaatctc ctttctgcta agagagaatt gacatattgt tctatttgtg
    58441 gacgtttgac agacgacgat ccttgttcta tctgtactga tccgactcgt gaccagacaa
    58501 caattttagt tcttgaggat agtagagatg tggcagccat ggaaaatatc caagaatacc
    58561 atggactcta tcatgtcctg catggcctca tttctcctat gaatggtatc agtccggacg
    58621 atatcaatct caagagcctt atgactcgtc ttatggatag tgaggtttca gaagtgattg
    58681 tggcgactaa tgctacagcg gatggtgaag cgacttccat gtatctttca cgtttgctca
    58741 agccagctgg tatcaaggtt acgcgtctag cacgaggtct cgctgtggga gcggacattg
    58801 agtatgcgga cgaagtgaca ctcttacgag cgattgaaaa tcggacagag ttgtaagtgt
    58861 aggcaaattt acgaactccc ttcatttata aaaaatcaaa gaggctgaaa atcgttccta
    58921 tcggcctctt tttgtatagt gtgatgagta ggatcgggtt caagttttaa aaaaccaagc
    58981 aaatatgata tactaaagag cgagtattct agtagaatta ggacaaataa tatgaaacaa
    59041 acgattattc ttttatatgg tggacggagt gcggaacgcg aagtctctgt cctttcagct
    59101 gagagtgtca tgcgtgcggt caattacgac catttcacag tcaagacttt ctttatcagt
    59161 cagtcaggtg actttatcaa aacacaggaa tttagtcatg ctccggggca agaagaccgt
    59221 ctcatgacca atgaaaccat tgattgggat aagaaagttg caccaagtgc tatctacgaa
    59281 gaaggtgcag tggtctttcc agtccttcac gggccaatgg gagaagatgg ctctgttcaa
    59341 ggattcttgg aagttttgaa aatgccttac gttggttgca acattttgtc atcaagtctt
    59401 gccatggata aaatcacgac taagcgtgtt ctggaatctg ctggtattgc ccaagttcct
    59461 tatgtggcta tcgttgaagg cgatgatgtg actgctaaaa tcgctgaagt ggaagaaaaa
    59521 ttggcttatc cagtcttcac taagccgtca aacatggggt ctagtgtcgg tatttctaag
    59581 tctgaaaacc aagaagaact ccgtcaagcc ttaaaacttg ccttccgata tgacagccgt
    59641 gtcttggttg agcaaggagt gaatgcccgt gaaattgagg ttggcctctt gggtaactac
    59701 gatgtcaaga gcacgctacc tggagaagtt gtcaaggacg ttgcctttta tgactacgat
    59761 gccaagtata ttgataacaa gattactatg gatattcctg ccaaaatcag tgatgatgtg
    59821 gtagctgtca tgcgtcaaaa tgcagaaaca gccttccgtg ccattggtgg ccttggtcta
    59881 tctcgttgcg atttcttcta tacagataag ggagagattt ttctcaacga gctcaatacc
    59941 atgccaggtt tcacccagtg gtctatgtac ccactacttt gggacaatat ggggatcagc
    60001 tacccagaac taatcgagcg tttggttgac cttgccaagg aaagttttga caagcgcgaa
    60061 gcgcatttga tataaaatga aagagagggt agaagccaga accatcactg caaggtgact
    60121 agagttctcg gacttcagcc ctttttaaag gagtagaaat gaaattaaca atccatgaag
    60181 ttgcccaagt tgttggagcc aaaaatgata tcagtatctt tgaggacacc cagttagaaa
    60241 aagctgagtt tgatagtcgt ttgattggaa ctggagattt atttgtgccc ctaaaaggtg
    60301 tgcgtgacgg tcatgacttt atcgaaagag cttttgaaaa tggtgcggca gcaaccctgt
    60361 ctgagaaaga ggttgcaaat catccctaca ttctagtaga tgatgttttg actgcctttc
    60421 aacaactagc tgcctactat cttgaaaaaa cagctgttga tgtctttgcg gttacgggtt
    60481 caaatggcaa gacaacgact aaggatatgt tggcgcattt actgtcaaca agatacaaga
    60541 cctacaaaac acaaggcaat tacaataatg agattggcct tccttacaca gttctccaca
    60601 tgcctgaagg aacagaaaag ttggtcttgg agatggggca ggaccacttg ggagatattc
    60661 atctcttgtc tgaattggct cgtccaaaaa cagccatcgt gaccttggtt ggagaagctc
    60721 atttggcctt tttcaaagat cgttctgaga ttgctaaagg aaaaatgcaa attgcagacg
    60781 gaatggcttc aggttccttg cttttagcgc cggctgaccc tatcgtagag gactatttgc
    60841 caactgataa aaaggtggtt cgttttggtc aaggagcaga gctggaaatt actgacttgg
    60901 ttgagcgcaa agatagtctg accttcaagg ccaatttctt agagcaagtc cttgatttgc
    60961 cagtaactgg caagtacaat gcgacaaatg ctatgattgc atcctatgtt gccttgcaag
    61021 aaggagtttc agaggagcaa attcgtttgg ccttccaaca tcttgaattg acgcgtaacc
    61081 gtaccgagtg gaagaaagca gccaatggag cagacatctt gtcagatgtt tacaatgcca
    61141 atccaactgc tatgaagctg attttagaga ccttctctgc cattccagcc aatgaaggtg
    61201 gcaagaaaat tgcagtgttg gcggatatga aggaacttgg tgtccagtct gttcaacttc
    61261 ataatcagat gattttgagc ctttcgccag atgtgcttga tactgttatt ttctacggag
    61321 aagatattgc tgaattagcc caacttgcta gtcaaatgtt cccaatcgga cacgtttatt
    61381 acttcaagaa aacagaagac caagaccaat ttgaagacct agttaagcag gtcaaagaaa
    61441 gccttggggc tcatgaccaa atcctgctca aaggctctaa ctctatgaat ctagccaagt
    61501 tggtagaaag tttagaaaat gaagacaagt gattttgtca agtatttgca aagaatgatt
    61561 gccattacag atactggatt aacctttaca aaagatccgt ttgaccgtga gcgctacgaa
    61621 gacttgcgag accttctatc tgaaatgttg aatcaagcat cagaccttga ttccgaagaa
    61681 gtggcagaag tcttgaagcc aacttctgct tatgcgactc ccttaatgga cgtccgtgct
    61741 tggattgttg aggacgaaaa gatttgtctg gttaggggac aaggagagga tagttgggct
    61801 ttgccaggtg gctttggtga agtcggctat tctccaactg aaaatattct caaggaaatt
    61861 gaagaagaaa ccggttttaa agccaaagtt gaaagactgc tagctgtttt tgataccaat
    61921 cgtttccaac tacagagcaa acaatatgca aagtttgttt ttgaatgtaa gcttctcgat
    61981 ggacaattcc aagaaaatca agaaatcgct gaccttcaat tttttgcaat tgacccactg
    62041 ccgaatttat ctgaaaaacg cattaccaag gagcaaatcg agattctttg gcaggtttat
    62101 caaggtcaga gggagcaata tcttgactaa gaagatgatt atcgtatttc taaattcatt
    62161 tttcttaagt agcatggtat aataaaatgc aggaaaattt tgaatcatga ggaagactag
    62221 atgaatttat gggatatttt ctttacgact caggcaaccg agccgcccaa atttgacctt
    62281 ttttggtatg ttagcctatt tacgctctta gccttaacct tttatacagc ccatcgctat
    62341 cgtgaaaaga aggtttacca acgatttttc caaatcttgc agactgttca gttaatcctt
    62401 ctttatggtt ggtactgggt caatcatatg ccactgtcag aaagcctacc cttttaccat
    62461 tgccgtatgg ctatgtttgt ggtactcttg cttcctggtc agtccaaata taaacaatac
    62521 tttgcattat tgggaacatt tgggacatta gcagcctttg tttatccagt gccagatgct
    62581 tacccttttc cacatatcac cattctatcc tttatctttg gtcatttagc actcttgggg
    62641 aactctctag tttatctatt gagacagtat aatgcgcgat tgctggatgt gaagggaatt
    62701 tttctcatga cctttgccct aaatgccttg atttttgtgg tcaatttggt gacaggtggc
    62761 gattacggat ttttgacaaa accgccattg gttggggatc acggtctagt agctaattat
    62821 ttacttgttt caattgtgct ggtagctact atcagtttga ctaagaaaat cttagaattc
    62881 tttttagctc aagaagcaga aaaaatgatt gcaaaggaag cttaacacag agctttcttt
    62941 tttgctctta gagagttttt acaagcagct tataaaataa gaatttctga atagacaaac
    63001 tcaaaaaatg gctgggaaat ttaggaaaaa agcaagcacg attaaatttt ttgtgttata
    63061 atattttgtg aatagctatg cctatgttta gctatggaat aatacgaagt gcgaaacttg
    63121 gaagatagag aggaagcgat gtaatggcta gagaaggctt ttttacaggt ctagatattg
    63181 gaacaagctc tgtcaaggtg cttgtggccg agcagagaaa tggtgaatta aatgtaattg
    63241 gcgtgagtaa tgccaaaagt aaaggtgtaa aggatggaat tattgttgat attgatgcag
    63301 cagcaactgc tatcaagtca gccatttccc aagcggaaga aaaggcaggc atttcgatta
    63361 aatcagtaaa tgtcggcttg cctggtaatc ttttgcaggt agaaccaact caggggatga
    63421 ttccagtaac atctgatact aaggaaatta cggatcaaga tgttgaaaat gttgtcaaat
    63481 cagctttgac aaagagtatg acacctgacc gtgaagtcat tacctttatt cctgaagaat
    63541 ttattgtgga tggtttccaa gggattcgtg acccacgtgg catgatgggg gttcgccttg
    63601 aaatgcgtgg tttgctttat acaggacctc gtactatctt gcacaatttg cgtaagacgg
    63661 ttgagcgtgc aggtgttcag gttgaaaata ttatcatttc accactagca atggttcagt
    63721 ctgttttgaa tgaaggggaa cgtgaatttg gtgctacagt gattgatatg ggggcaggtc
    63781 aaacgactgt cgctacaatc cgtaatcaag aactccagtt cacacatatt ctccaagaag
    63841 gtggagatta tgtaactaaa gatatctcca aggttttgaa aacctctcgc aaattagcgg
    63901 aaggcttgaa actgaattac ggggaagcct atccgcctct tgcaagcaaa gaaaccttcc
    63961 aagtagaggt tattggagaa gtggaagcag tcgaagtgac ggaagcctac ttgtcagaaa
    64021 ttatttctgc acgaatcaag cacatccttg aacaaatcaa gcaagaatta gatagaaggc
    64081 gtctattgga cctccctggt ggtattgtct taatcggtgg gaatgccatt ttaccaggta
    64141 tggttgagct tgctcaggaa gtctttggcg tccgtgtcaa gctttatgtt ccaaatcaag
    64201 ttggtatccg taatccagcc tttgcgcatg tgattagttt atcagaattt gcgggtcaat
    64261 taacagaagt taatcttttg gctcagggag cgataaaagg tgagaatgac ttaagtcatc
    64321 agccaattag ttttggtggg atgctgcaaa aaacagctca gtttgtacaa tcaacgcctg
    64381 ttcaaccagc tcctgctcca gaagtagagt cggtggcgcc tacagaacca atggcggatt
    64441 tccaacaagc ttcacaaaat aaaccgaaat tagcagatcg tttccgtggc ttgatcggaa
    64501 gcatgtttga cgaataaaga ggaaaaataa attatgacat tttcatttga tacagctgct
    64561 gctcaagggg cagtgattaa agtaattggt gtcggtggag gtggtggcaa tgccatcaac
    64621 cgtatggtcg acgaaggtgt tacaggcgta gaatttatcg cagcaaacac agatgtacaa
    64681 gcattgagta gtacaaaagc tgagactgtt attcagttgg gacctaaatt gactcgtggt
    64741 ttgggtgcag gaggtcaacc tgaggttggt cgtaaagccg ctgaagaaag cgaagaaaca
    64801 ctgacggaag ctattagtgg tgccgatatg gtcttcatca ctgctggtat gggaggaggc
    64861 tctggaactg gagctgctcc tgttattgct cgtatcgcca aagatttagg tgcgcttaca
    64921 gttggtgttg taacacgtcc ctttggtttt gaaggaagta agcgtggaca atttgctgta
    64981 gaaggaatca atcaacttcg tgagcatgta gacactctat tgattatctc aaacaacaat
    65041 ttgcttgaaa ttgttgataa gaaaacaccg cttttggagg ctcttagcga agcggataac
    65101 gttcttcgtc aaggtgttca agggattacc gatttgatta ccaatccagg attgattaac
    65161 cttgactttg ccgatgtgaa aacggtaatg gcaaacaaag ggaatgctct tatgggtatt
    65221 ggtatcggta gtggagaaga acgtgtggta gaagcggcac gtaaggcaat ctattcacca
    65281 cttcttgaaa caactattga cggtgctgag gatgttatcg tcaacgttac tggtggtctt
    65341 gacttaacct tgattgaggc agaagaggct tcacaaattg tgaaccaggc agcaggtcaa
    65401 ggagtgaaca tctggctcgg tacttcaatt gatgaaagta tgcgtgatga aattcgtgta
    65461 acagttgttg caacgggtgt tcgtcaagac cgcgtagaaa aggttgtggc tccacaagct
    65521 agatctgcta ctaactaccg tgagacagtg aaaccagctc attcacatgg ctttgatcgt
    65581 cattttgata tggcagaaac agttgaattg ccaaaacaaa atccacgtcg tttggaacca
    65641 actcaggcat ctgcttttgg tgattgggat cttcgccgtg aatcgattgt tcgtacaaca
    65701 gattcagtcg tttctccagt cgagcgcttt gaagccccaa tttcacaaga tgaagatgaa
    65761 ttggatacac ctccattttt caaaaatcgt taagtaaatg aatgtaaaag aaaatacaga
    65821 acttgttttt cgagaagttg cagaggctag tctgagtgct catcgagaga gtggttcggt
    65881 ctctgtcatt gcagttacca agtatgtaga tgtaccgaca gcggaagcct tgcttccgct
    65941 aggtgttcat catatcggtg aaaatcgtgt agataagttt ctggaaaaat atgaagcttt
    66001 aaaagatcga gatgtgactt ggcatttgat tggtaccttg caaagacgta aggtgaaaga
    66061 tgtcattcaa tacgttgatt atttccatgc attggactca gtaaagctag caggggaaat
    66121 tcaaaaaaga agtgaccgag tcatcaagtg tttccttcaa gtaaatattt ctaaagaaga
    66181 aagcaaacac ggtttttcga gagaggaact gctggaaatc ttgccagagt tagccagact
    66241 agataagatt gaatatgttg gtttaatgac gatggcacct tttgaggcta gcagtgagca
    66301 gttgaaagag attttcaagg cgacccaaga tttacaaaga gaaattcaag agaaacaaat
    66361 tccaaatatg cctatgaccg agttaagtat gggaatgagt cgtgattata aagaagcgat
    66421 tcaattcggt tccacttttg ttcgtatagg tacatcattt tttaagtagg agagaaccat
    66481 gtctttaaaa gatagattcg atagatttat agattatttt acggaggatg aggattcaag
    66541 tctcccttat gaaaaaagag atgagcctgt gtttactcca gtaaattctt cacaggaacc
    66601 ggctctccca atgaatcaac cttcacagtc ggctggtaca aaagagaaca atatcaccag
    66661 acttcatgca agacaacagg aattggcaaa tcagagtcag cgtgcaacgg ataaggtcat
    66721 tatagatgtt cgttatccta gaaaatatga ggatgcaaca gaaattgttg atttattggc
    66781 aggaaacgaa agtatcttga ttgattttca gtatatgaca gaggtgcagg ctcgtcgttg
    66841 tttggactat ttggatggag cttgtcatgt tttagctgga aatttgaaaa aggtagcttc
    66901 taccatgtat ttgttgacac cagtgaatgt tattgtaaat gttgaagata tccgtttacc
    66961 agatgaagat caacagggtg agttcggttt tgatatgaag cgaaatagag tacgataatg
    67021 atttttttaa ttcgtatgat ttataatgca gtggatattt actccctgat tttggtagcc
    67081 ttcgctgtca tgtcttggtt tccaggtgcc tacgaatcca gtttaggtcg ttggattgta
    67141 gcgttggtga aaccagtgct tgctcccttg caacgcctgc ctttacagat agcgggtctt
    67201 gatttatctg tttgggtcgc gattgttttg gttcgatttt taggagaaaa cctagtgcgt
    67261 tttctggcga tgataggatg aataaaggga tttatcagca tttctccata gaagatcgtc
    67321 catttcttga caagggaatg gaatggataa agaaggtaga agatagctat gctccttttt
    67381 taactccttt tatcaatcct catcaggaga agctattaaa gattttggcc aaaacctatg
    67441 gtcttgcttg tagcagtagt ggggaattcg tctcgagtga gtatgttcga gttttattat
    67501 acccagatta tttccaacca gagttttcag attttgaaat atctctccag gaaattgtgt
    67561 attccaataa atttgaacat ttaacgcatg ctaagatttt agggacagtc atcaatcaat
    67621 tagggattga acggaaactt tttggagata tcctagtaga tgaagaacgg gcgcagatta
    67681 tgattaatca gcagtttctt cttctctttc aagatggact aaagaaaatt ggtcgtatac
    67741 ctgtttcgct ggaggaacgt cctttcaccg agaaaataga taagctagaa cagtatcgag
    67801 aactggattt atctgtgtct agttttcgat tagatgttct ttgttcaagt tggagacttg
    67861 attagtgtga gaaaatttgg tcgcttgaga ttacttcaag ataagggaca aacgaaaaaa
    67921 gagaagaaaa aaataaccgt ccagttatta ttaagtaagt gaggaataga atgccaatta
    67981 catcattaga aataaaggac aagacttttg gaactcgatt cagaggtttt gatccagaag
    68041 aagtcgatga atttttagat attgtggttc gtgattacga agatcttgtg cgtgcgaatc
    68101 atgataaaaa tttgcgtatt aagagtttag aagagcgttt gtcttacttt gatgaaataa
    68161 aagattcatt gagccagtct gtattgattg ctcaggatac agctgagaga gtgaaacagg
    68221 cggcgcatga acgttcaaac aatatcattc atcaagcaga gcaagatgcg caacgcttgt
    68281 tggaagaagc taaatataag gcaaacgaga ttcttcgtca agcaactgat aatgctaaga
    68341 aagtcgctgt tgaaacagaa gaattgaaga acaagagccg tgtcttccac caacgtctca
    68401 aatctacaat tgagagtcag ttggctattg ttgaatcttc agattgggaa gatattctcc
    68461 gtccaacagc tacttatctt caaaccagtg atgaagcctt taaagaagtg gttagcgaag
    68521 tacttggaga accgattcca gctccaattg aagaagaacc aattgatatg acacgtcagt
    68581 tctctcaagc agaaatggaa gaattacaag ctcgtattga ggtagccgat aaagaattgt
    68641 ctgaatttga agctcagatt aaacaggaag tggaaactcc aactcctgta gtgagtcctc
    68701 aagttgaaga agagcctctg ctcatccagt tggcccaatg tatgaagaac cagaagtagc
    68761 tccagtgcat ccgacaggtc caacaccagc tacagaaact gttgattcag caccgggatt
    68821 tgaagcaccg caagaatctg ttacaatttt ataagaaata ttctgagaac aatatcttat
    68881 ccttatattc ccagcgagca ggagatggtg tgagtcctgc attccctatc gataagatta
    68941 tcctctcaaa ctatcaagtc tgaatctagt aagatttgac gttccccacg ttacgggata
    69001 agagggagaa agactaaaac tttttccgaa taaaggtggt accacgattt tcgtcctttt
    69061 tggaagtcgt ggtttttaat ttgttattat ttataaagga gataccatga aactcaaaga
    69121 cacccttaat cttgggaaaa ctgaattccc aatgcgtgca ggccttccta ccaaagagcc
    69181 agtttggcaa aaggaatggg aagatgcaaa actttatcaa cgtcgtcaag aattgaacca
    69241 aggaaaacct catttcacct tgcatgatgg ccctccatac gctaacggaa atatccacgt
    69301 tggacatgct atgaacaaga tttcaaaaga tatcattgtt cgttctaagt ctatgtcagg
    69361 attttacgca ccatttattc ctggttggga tactcatggt ctgccaatcg agcaagtctt
    69421 gtcaaaacaa ggtgtcaaac gtaaagaaat ggacttggtt gagtacttga aactttgccg
    69481 tgagtacgct ctttctcaag tagataaaca acgtgaagat tttaaacgtt tgggtgtttc
    69541 tggtgactgg gaaaatccat atgtgacctt gactcctgac tatgaagcag ctcaaattcg
    69601 tgtatttggt gagatggcta ataagggtta tatctaccgt ggtgctaagc cagtttactg
    69661 gtcatggtca tctgagtcag cccttgctga agcagagatt gaataccatg acttggtttc
    69721 aacttccctt tactatgcca acaaggtaaa agatggcaaa ggagttctag atacagatac
    69781 ttatatcgtt gtctggacaa cgactccatt tactatcaca gcctctcgtg gtttgacggt
    69841 tggtgcagat attgattacg ttttggttca acctgctggt gaagctcgta agtttgtcgt
    69901 tgctgctgaa ttattgacta gcttgtctga gaaatttggc tgggctgatg ttcaagtttt
    69961 ggaaacttac cgtggccaag aactcaacca catcgtaaca gaacacccat gggatacagc
    70021 tgtagaagag ttggtaattc ttggtgacca cgttacgact gactctggta caggtattgt
    70081 ccatacagcc cctggttttg gtgaggacga ttacaatgtt ggtattgcta ataatcttga
    70141 agtcgcagtg actgttgatg aacgtggtat catgatgaag aatgctggtc ctgaatttga
    70201 aggtcaattc tatgaaaagg tagttccaac tgttattgaa aaacttggta acctccttct
    70261 tgcccaagaa gaaatctctc actcatatcc atttgactgg cgtactaaga aaccaatcat
    70321 ctggcgtgca gttccacaat ggtttgcctc agtttctaaa ttccgtcaag aaatcttgga
    70381 cgaaattgaa aaagtgaaat tccactcaga atggggtaaa gtccgtcttt acaatatgat
    70441 ccgtgaccgt ggtgactggg ttatctctcg tcaacgtgct tggggtgttc cacttcctat
    70501 cttctacgct gaagatggta cagctatcat ggtagctgaa actattgaac acgtagctca
    70561 actttttgaa gaacatggtt caagcatttg gtgggaacgt gatgccaaag acctcttgcc
    70621 agaaggattt actcatccag gttcaccaaa cggcgagttc aaaaaagaaa ctgatatcat
    70681 ggacgtttgg tttgactcag gttcatcatg gaatggagtg gtggtaaacc gtcctgaatt
    70741 gacttaccca gccgaccttt acctagaagg ttctgaccaa taccgtggtt ggtttaactc
    70801 atcacttatc acatctgttg ccaaccatgg cgtagcacct tacaaacaaa tcttgtcaca
    70861 aggttttgcc cttgatggta aaggtgagaa gatgtctaaa tctcttggaa ataccattgc
    70921 tccaagcgat gttgaaaaac aattcggtgc tgaaatcttg cgtctctggg taacaagtgt
    70981 tgactcaagc aatgacgtgc gtatctctat ggatatcttg agccaagttt ctgaaactta
    71041 ccgtaagatt cgtaacactc ttcgtttctt gattgccaat acatctgact ttaacccagc
    71101 tcaagataca gtcgcttacg atgagcttcg ttcagttgat aagtacatga cgattcgctt
    71161 taaccagctt gtcaagacca ttcgtgatgc ttacgcaaac tttgaattct tgacaatcta
    71221 caaggccttg gtgaacttta tcaacgttga cttgtcagcc ttctaccttg attttgccaa
    71281 agatgttgtt tacattgaag gtgccaaatc actggaacgc cgtcaaatgc agactgtctt
    71341 ctatgacatt cttgtcaaaa tcaccaaact cttgactcca atccttcctc acactgcgga
    71401 agaaatctgg tcatatcttg agtttgaagc cgaagacttc gtccaattgt cagaattacc
    71461 agaagttcaa acttttgcta accaagaaga aatcttggat acatgggcag ccttcatgga
    71521 cttccgtgga caagcacaaa aagccttgga agaagctcgt aatgcaaaag ttatcggtaa
    71581 atcacttgaa gcacacttga cagtttatcc aaatgaagtt gtgaaaactc tactcgaagc
    71641 agtaaacagc aatgtagctc aacttttgat cgtgtctgag ttgaccatcg cagaagaacc
    71701 agctccggaa gctgccctta gcttcgaaga tgtagtcttc acagttgaac gcgctgcagg
    71761 tgaagtatgt gaccgttgcc gtcgtattga cccaacaaca gcagaacgta gctaccacgc
    71821 agtcatctgt gaccactgtg caagtatcgt agaagaaaac tttgcagatg cagtcgcaga
    71881 aggatttgaa gagaaataag attgaaaagt ctaggtaaaa ctcaatttga gaagaaaaga
    71941 caactaattt tatagtctat taaacgcatt gtatcacgtt tttgaacacc tgatatgatg
    72001 cgttttttat ttattttaaa aatttgcgag gtatgacttt ttatactcaa caagaatcaa
    72061 agagaaactt agcaagctaa cagtagtaat ataaaatagg aatttgatat tagggataag
    72121 attggtaaat agtgtaatat ttttacaaca ataaatttat atagttattt ctggtttctg
    72181 aaaagtatta tattatattt tatttcatat tatacaaatt tttattttat aatatcagaa
    72241 aatacttttt ttaaaaagca aatatgatac aattttattt gaaaaaaaat aaaaaaggag
    72301 attttattat gaaatcaagt ggtatcgtcg gtcttgtggg aggaatttta cttcttattt
    72361 gtccttttgt cttgttggga acagcggtaa atacagctgc tacaactctt aatggaggag
    72421 ctactgcagg ggctttttca ggtgttgcct tactcttgaa tgccttgaag attgcaaatc
    72481 ttgttcttgg tatcattgct attgtttact ataaaggaga taagcatgta ggtgcagctc
    72541 cgtctgtact aatgattgtt tctggtgaag ttagtctcat tccattctta ggatgggttg
    72601 gggggattct tgctattatc ggaggatctc tattccttgc aacattgaag aaattcaaat
    72661 cagaagaata aaaggtattt tagcatgaaa agaacaaaaa agtttatcgg tataggagta
    72721 gctctattat ctctttctct tctagttgca tgtggaacat aaagttcaaa gaatacttca
    72781 acaagtaatg atgagaagac agtagcaaca tccaatagtt caaaagaaac aatcactttc
    72841 gatacaccgg ttgtaacaga cgatgcgatt gaatcaatac gcacttatgc agattatata
    72901 gatctttata aaaatatttt tgatgattat tttactaaag ctgaggaagg tttcaaaggc
    72961 acaactatgg aaaataatga ctcgtttact aaactaaaag agtcaactca aaaattattc
    73021 gatgcgcaga aaaaaaggtt aaataatgaa gatagaatag aaacaaccaa aaacaatgtg
    73081 attgccaaac attgtcaaac agtcctttcc tttttggttt tgactagctt ttttgtgaaa
    73141 aattgtgtaa aatagaatag ataaacgagg ggaaacctcg gaaaatttaa aggagaatcc
    73201 atctaatggt aaaattggtt tttgctcgcc acggtgagtc tgaatggaac aaagctaacc
    73261 ttttcactgg ttgggctgat gttgatttgt ctgaaaaagg tacacaacaa gcgattgacg
    73321 ctggtaaatt gatcaaagaa gctggtatcg aatttgacca agcttacact tcagtattga
    73381 aacgtgctat caaaacaact aacttggctc ttgaagcttc tgaccaattg tgggttccag
    73441 ttgaaaaatc atggcgcttg aacgaacgtc actacggtgg tttgactggt aaaaacaaag
    73501 ctgaagctgc tgaacaattt ggtgatgagc aagttcacat ctggcgtcgt tcatacgatg
    73561 tattgcctcc aaatatggac cgtgatgatg agcactcagc tcacacagac cgtcgttatg
    73621 cttcacttga cgactcagtc attccagatg ctgaaaactt gaaagtgact ttggaacgtg
    73681 ctcttccatt ctgggaagat aaaatcgctc cagctcttaa agatggtaaa aacgtattcg
    73741 taggagctca cggtaactca atccgtgccc ttgtaaaaca catcaaaggt ttgtcagatg
    73801 atgagatcat ggacgtggaa atccctaact tcccaccatt ggtattcgaa ttcgacgaaa
    73861 aattgaacgt tgtttctgaa tactaccttg gaaaataaaa aattgtaagc ctaggattga
    73921 tttctaggct ttttatgtta gtatggaagt atgataagga ataaaaaaca agattatgta
    73981 ctggcctaca agcaaccagc ttcaaccact tacatgggtt gggaagaaga agctttaccg
    74041 ataggcaatg gttctttagg agcaaaagta tttggcctta taggggctga acggattcaa
    74101 tttaatgaaa aaagtctctg gtctggaggt ccacttcctg atagttcaga ttatcagggt
    74161 ggaaatcttc aggatcagta tgttttttta gctgagattc ggcaggcttt ggagaagaga
    74221 gattacaatc tggctaagga actggctgag cagcacctaa ttgggccaaa aacgagtcaa
    74281 tatgggacct atctgtcttt tggggatatt cacattgagt tcagccagca aggtacgact
    74341 ttgtctcagg tgacggacta tcagagacag ctgaatatta gtaaggcact tgcgacgact
    74401 tcttatgtct ataagggaac gcgatttgaa cgtaaagctt ttgcgagttt tccagatgat
    74461 ctcttgattc aatgttttac taaggaaggg ttggaaactc tagattttac tatagaacta
    74521 tccttgacct gtgatttggc ttctgatgga aagtatgagc aggaaaaatc tgattacaag
    74581 gagtgtaagt tggatattac tgattctcat atcttgatga agggaagagt taaggataat
    74641 gatctgcggt ttgctagtta tctagcttgg gaaacggatg gagatattag agtttggtca
    74701 gatagggttc agatatcagg agccagttat gccaatctct tcttggccgc taagacggat
    74761 tttgcccaaa atcctgctag caattatcgc aagaaactag atttagagca acaggtgata
    74821 gacttggtgg acacagctaa agaaaagggc tatacccaat tgaaatcaag gcatatcgag
    74881 gactaccaag ccttattcca gcgtgttcaa ttggatttgg aagctgatgt tgacgcatcc
    74941 actacagatg atttgttaaa aaattataag ccacaagaag ggcaggcttt ggaggagctg
    75001 ttcttccagt atggacggta tttattgatt agttcgtcca gagactgccc agatgctcta
    75061 ccagctaacc tacagggagt ctggaatgcg gtcgacaatc ctccttggaa ttcggactat
    75121 cacttaaatg tcaatctgca gatgaattat tggccagcct atgttaccaa tctcctagag
    75181 acggtctttc cagtcatcaa ctatgtagat gatttgcgtg tctatggtcg tctagcggct
    75241 gtaaagtatg caggaatcgt ctctcaaaaa ggtgaggaaa atggttggtt ggttcatact
    75301 caagcgactc cctttggttg gacggcacct ggttgggatt actattgggg ttggtcacca
    75361 gctgccaatg cgtggatgat gcaaaccgtt tatgaagcct attcatttta tagggaccaa
    75421 gactatctca gggagaaaat ttatcccatg ttgagggaaa cggttcgttt ttggaatgcc
    75481 tttttacata aggatcagca ggcgcagcgt tgggtctctt ctccgtctta ttccccagaa
    75541 catgggccga tttcgattgg caatacctat gaccaatctc tgatttggca gttatttcat
    75601 gattttattc aggctgctca ggaattggga ctggatgagg acttgttgac tgaggttaag
    75661 gagaagtctg atttactaaa tcctttgcaa atcactcaat ctggtcgaat cagggagtgg
    75721 tatgaggagg aagagcagta ttttcaaaat gagaaagtgg aggcccagca tcggcacgct
    75781 tcccatctag tgggactcta ttctggcaat ctctttagct acaagggaca agagtatatt
    75841 gaagcggcgc gtgctatcct caatgatcgt ggagatggcg gcacaggctg gtccaaggct
    75901 aataagatca atctctgggc gcgtttggga gatggcaatc gagcccataa attattggca
    75961 gagcagttaa agacatccac cttgccaaat ctttggtgta gccatcctcc ttttcagata
    76021 gatggtaatt ttggtgctac tagtggcatg gcagaaatgt tactccagtc tcatgcagct
    76081 tatctggtac ctctagctgc cctacctgat gcttggtcaa caggttctgt ttcaggctta
    76141 atggcacgtg gacattttga agtgagcatg agctgggaag ataaaaaact cttacagttg
    76201 accattttat caaggagtgg aggagatttg cgagtttctt atccagatat tgagaagagt
    76261 gtgattaaaa tgaatcaaga aaaaataaaa gcgaaatgca tggggaaaga ttgtatttcg
    76321 gtggcaacag cagaaggtga tcttgttcaa ttttattttt aagaagatgt tataaggcag
    76381 taatttgaaa cttcctttta ataaggattt gagaatatag gcagtttcca actagttgaa
    76441 aaagcgttat aatgataata ggaagtaata ctcaatgaaa atcaaagagc acaaactagg
    76501 aagctagccg caggttgctc aaaacagtgt tttgaggttg tagatggaag ctgacgtggt
    76561 ttgaagagag attttcgagg agtataattt gtttgataga gggtgggtct gatggcttat
    76621 attgagatga aacactgtta caagcgttat caggttgggg acacggagat tgtggccaat
    76681 cgtgatgtga attttgagat tgaaaagggg gagctggtta ttatccttgg tgcttcaggt
    76741 gcaggcaagt caacagttct taaccttctt gggggaatgg ataccaatga tgaaggggaa
    76801 atctggattg atggtgttaa tattgcggat tatagttccc accagcgtac caattaccgt
    76861 agaaatgatg tggggtttgt ttttcagttt tataatctag tttctaatct gacagctaag
    76921 gaaaatgtgg aactggcttc tgaaattgtg acagatgcct tgaatcctga tcaggtcttg
    76981 acagatgtag gtctggctca tcgtctcaat aactttccag cccagctttc tggaggggag
    77041 caacagcgag tctccattgc acgcgcggta gccaaaaatc ctaaaattct cctttgtgat
    77101 gaaccgactg gagccttgga ttatcagacg ggcaagcagg ttttgaaaat tctccaagac
    77161 atgtctcgtc aaaagggagc gacggtgatc atcgtgactc ataatggagc tttggcgccc
    77221 attgctgatc gcgtgattca aatgcacgat gccagtgtca aggatgtggt gctcaaccag
    77281 catcctcagg atattgacag tttggagtac tagcatgatc aagcgaaaaa cttattggaa
    77341 ggacttaatt cagtccttca caggctccaa ggggcgtttt ttatccatct tgatcctgat
    77401 gatgttggga tctctagcct tagtaggcct caaagtaacc agtcccaaca tggaggcgac
    77461 agctaatgct tatttaacaa ctgctcaaac cttggatttg gcagtcatgt ctaactatgg
    77521 cttggatcaa gcagaccaag aagaactaaa acagacggag ggcgcagagg tcgagtttgg
    77581 ctatttgaca gatgtgacta tggataatgg gcaggatgcc attcggctgt actccaaacc
    77641 agagcgaatt tcaacctttc agctaagaaa gggacgactt cctcagtcag acaaggaaat
    77701 cgctttggcc actcatttgc aaggccaata cagcgtggga caggagatta gttttaaaga
    77761 aaaagaagag ggtcattcct ctttaaaaga ccatacttat accattactg gttttgtgga
    77821 ttcggctgaa atcctctccc agcgagatat gggctacgca ggaagtggaa gtgggactct
    77881 gacagcctat ggggtgattt tacctagtca gtttgatcag aaagtctaca atatagctcg
    77941 tttgaaatat caagatttag caggtttaaa tgccttttca tcagcttatg aagaaaaatc
    78001 caagcaacat caggaagacc ttgaacaaac tttatcagat aatggcaagg tacgtctgca
    78061 acttttgaaa aaagaaggac aagagtctct agacaagggg caagagaccc ttgacaaggc
    78121 tcagactaat ttgcaggaag gcaagcgtcg tttagcagct gctcaagctc gtatacaggc
    78181 tcaagaaagt caactagcct tgtttcctca agttcagaga gagcaggcta gtgctcaact
    78241 tacccaagcc aagcaggaat tgggcaagga agaggataaa ctaaagcaag ctgaacaaaa
    78301 tctagcccaa gaaaaggaaa aattagaaaa acatcagcaa gtcttggacg atttggcgga
    78361 gccaaggtat caggtctata atcgtcagac catgccaggt ggtcagggct atcttatgta
    78421 tagcaatgct tcatccagta ttcgagcagt gggcaatatc tttcctgtgg tactttatgc
    78481 cgtagcatcc atggtgacct ttacgaccat gactcgcttt gtagacgaag agcgaactca
    78541 tgcagggatt tttaaggcct tgggttaccg tagtaaggat attatcacca agtttctcct
    78601 ttatggacta gtagctggga ctgtcggaac ggctctaggt agtatacttg gtcattattt
    78661 gctagccagt gtaatttcaa gtgtcattac aaaaggcatg gtggtgggag aaacccagat
    78721 tcagttctat tggacctata gcttactagc tcttgtcttg agctggttgg cgagtgtgtt
    78781 accagcctat ctggtggctt ggagggaact tcatgccgaa gcagcccagc ttctacttcc
    78841 taaacctcct gtcaaaggag ctaaaatctt attggagcgt atcggtttta tctggcgtcg
    78901 tctcagtttt actcataagg taacagcccg caacatcttt cgttataagc agagaatgtt
    78961 gatgacaatc tttggtgtgg caggttctgt agctctgctc tttgcaggtt tgggaatcca
    79021 atcttctgta gcaggagttc cgtctaaaca gtttcaacaa atccaacagt atcagatgct
    79081 tgtctctgaa aatcctagtg cgaccaatca ggacaaggta gagctagcag aagtgttgaa
    79141 agggcaggag atactagcct accagaaaat ctattctaaa acgctagaca aggatttcaa
    79201 aggcaaggct ggtcttcaaa acattactct tatgatgata gagaaggaag atttgactcc
    79261 ctttatccat cttcaacatc atcagcagga gctgacatta aaagatggca tcgttattac
    79321 agctaaactc gcccagctgg caggtgtcaa ggttgggcag actttagaaa ttgaaggtaa
    79381 ggaactaaag gtcgctgcta ttactgagaa ctacgttggt cactttattt atatgagtca
    79441 ggctagctat gagcaacttt acggacagct accccaagcc aacacttatc tggtctcatt
    79501 aagggatacc agtgcaacta gtatcgaaag tcaggcgggc ttgcttatga atcaatctgc
    79561 ggtgtccagc gttgtccaaa atgcttcagc cattcgactc tatcgctagc tcactcaatc
    79621 agaccatgac catcttggtc atcgtatcag ttctattagc tattgtcatc ctttacaatc
    79681 tgaccaatat caacgtagct gagagaatcc gtgaactctc cactatcaag gttctcggtt
    79741 ttcataataa tgaagtcacc ctctacattt accgtgagac gattgtgctg tcccttgtgg
    79801 gaatcgtact tggtctggta gctggtttct atttacacca atttttgatt caaatgattt
    79861 cgcctgcgac tattctcttt tatccgcagg taggctggga agtctatgta atcccagtgg
    79921 caacagtaag catcattttg accttgcttg gtttcttcgt caattattat ctgagaaagg
    79981 ttgatatgtt agaagccctg aaatctgtag agtaaggtag ttatttttag ctgattgaac
    80041 ttctatttac taatattcaa aaatcctctg tcacaaagag cagggagctc tttgtgacag
    80101 aggatttttt ctatagggct ttagcagctg caattgcggc ttcgaagttt ggctcagaat
    80161 tgatattatc cacgtattca acgtagcgaa tcgtattgtc agtatcgagg acaaagactg
    80221 cgcgtgctaa taggtgccat tcgttgatca agagggcata atcgcgcccg aaagaatggt
    80281 caaagtagtc tgaaagcata atggcattgt caaggccttc agcaccgcac caacgttttt
    80341 gagcaaaagg taggtccatt gaaacagtca atacgaccgt gttgtccagt ccagccaatt
    80401 cttcattaaa acgacgtgtt tgagttgagc agatgcctgt atcgatagaa ggaacgacac
    80461 tcaagacttt tttcttgcca tcaaaatcag ccagagattt tttagaaaga tctgttgtag
    80521 taagagaaaa atcaagcgcc ttgtcgccga cttgtagttg tttacctgta aagctcacag
    80581 gatttccgag aaaagttacc ataggatact ccaatctttt ttcttccatt gtatctgaaa
    80641 cagtcagaat tttccaatga tttgaccgga aatgtgggca tagaaaaaac gccagctcac
    80701 atgagaatga cgtttttcag aggcttattt tgccaatcct tcagcaatct tgtcaaggtt
    80761 gtatttcatc atgctgtagt agctgtcgcc ttctttacct tgttctgcga tagagtcagt
    80821 aaagatttgt gcgtagattg ggatgtttgt gtcttgagaa acagttttca ttggacggtc
    80881 atccacactt gattctacaa agagtgatgg aacttttgtt tggcgaagtt tttcaaccaa
    80941 ggtcttgatt tgttcaggag ttccttcttc ttcagtattg atttcccaga tgtaagcact
    81001 tgggacacca taggctttag agaagtattt gaatgctcct tcgctggtta caatgagttt
    81061 cttttcagca gggatcttat taaatttatc cttactttct ttatcaagtt tgtctaactt
    81121 atcagtatat tctttgagat ttttttcata gaattcttta ttgttagggt ctttggcgct
    81181 caattgtttg gcgatatttt tagcaaaaat aataccgttt tcaaggttaa gccaagcgtg
    81241 tgggtcttct tttccttttt cattttgacc ttcaaggtag ataacatcaa cgccgtcgct
    81301 gactgcgaag tagtctttgt tttcagtttt cttggcattt tctaccaatt ttgtaaacca
    81361 agcattgcca cctgtttcaa ggttgatacc gttatagaaa atcaaatcag cctcagaagt
    81421 tttcttaacg tcttcaggaa gtggttcgta ttcgtgtggg tcttgcccaa tcggaacgat
    81481 actatgaagg tcaattttgt caccagcaat atttttagta atatcagcga tgattgagtt
    81541 tgtagcaaca acttttagtt tttgaccaga agttgtatct ttttttccgc tagcacatgc
    81601 tacaagaatg attgcagaaa gaaagagaac gagtaatgta cctaattttt tcattagatc
    81661 ctccaaatta ttagggcttt gccccttatt ttaacaaatg tttatttttc agtttcaaat
    81721 atcgttgttt gggagcgata aagaagctaa tgagaaagaa actagcagct gtaagcacga
    81781 tactagaacc tgccgcaaca ttaaaactat agccaataaa gagtcccaaa actgaagcag
    81841 tagctccgaa ggttgaggaa aggaaaatca tgcttttcag actattagca tacagataag
    81901 cagttgcagc tggggtaatc agcatggcta caatcaggat agttccgaca ctttgcatgg
    81961 ctgtcacaga cacgagagtc aggagtacca tgagaaggta gtgatagaaa ttgacaggca
    82021 ttcccatggc tttagccaag agttcatcaa aggaagttat caagagttgc ttgaagaaaa
    82081 tccagattaa caagaggatg gctgccccca cacccatagt aataaacata tccgtatctt
    82141 ggacggccag gatattacca aaaaggatat ggaaaaggtc agttgaactt ttagcgacac
    82201 caatcaagat gataccgagg gctaagaaag aagaaaaggt aatgccgatg gcggtatcgc
    82261 ttttgataat cgagtttcct ttgatgtagg taatgatgat ggcagctagc aatccaaaga
    82321 caatggctcc gataaagaag tcaaggccca agatgaagga gagggctaca cctggtaaga
    82381 cagcatgtga aatggcatct cccatgagtg acatcccgcg tagaataatg aaacatccca
    82441 cagctccagc tacaatcccg acgacaatag ctgttatcaa ggcattttgt aggaaatgga
    82501 atttttgcaa tccatcgata aattctgcaa tcataggtca cctccattga aaaagagttg
    82561 attaccgtaa gcttctttta gattggtttc ggtaaaagtt tcttttgttg gaccaaaggc
    82621 aatcacttct cgattgacaa gtaagacttg atcgaagtag tggggaatct tgctgaggtc
    82681 gtggtgaacg atgagaaccg tcttcccagc ttttttcaaa tctctcagcg tattcatgat
    82741 gatttcctca ctgacagagt caatcccagc aaagggttca tccaagagga tatagtcggc
    82801 ttcctgcacc aaacatctgg caatcaaaac ccgctggaat tgacctccag acagttgact
    82861 aatttgacgt tcagcgtagt cagctaggcc gacgatttca agggcctctt gcactttctt
    82921 ccaatgttta gcctttaaac ttcgaaagag aggaatagag ggaaatagtc ctaacgagac
    82981 gcattccttg accttgatgg gaaagttgta gtcgatattg attttttgtt cgacataggc
    83041 aattcggtgt aaggattttt taacttcctt gtcatcgaga aatgcctgac cttgatgtgg
    83101 gataattccc agcatacctt ttaatagtgt tgatttccca gcgccgtttg gaccaatgat
    83161 gccggtaatt gttggtccat ggagcactag tgaaatatcc ttaagtgcca acgtttcttt
    83221 gtaggagaca ctgaggtttt cgatacgtat cataaacttg tattcctcct gtctcttaat
    83281 atacattaaa aaaaaaatta agtcaagtta atttttgaaa aaattaaaat aataactgaa
    83341 aaataga
//
LOCUS       DAVBBO010000002        80452 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ST1
            SAMEA2066453-rid20184263.denovo.002, whole genome shotgun sequence.
ACCESSION   DAVBBO010000002 DAVBBO010000000
VERSION     DAVBBO010000002.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2066453
            Sequence Read Archive: ERR351777
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 80452)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 80452)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980402.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980402.1
            Genome Coverage       :: 176x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:17:33
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,141
            CDSs (total)                      :: 2,104
            Genes (coding)                    :: 1,953
            CDSs (with protein)               :: 1,953
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 16S)
            partial rRNAs                     :: 1 (23S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 151
            CDSs (without protein)            :: 151
            Pseudo Genes (ambiguous residues) :: 0 of 151
            Pseudo Genes (frameshifted)       :: 73 of 151
            Pseudo Genes (incomplete)         :: 76 of 151
            Pseudo Genes (internal stop)      :: 40 of 151
            Pseudo Genes (multiple problems)  :: 32 of 151
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..80452
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2066453-rid20184263.denovo.002"
                     /strain="ST1"
                     /db_xref="taxon:1313"
     gene            complement(134..1882)
                     /locus_tag="VQU30_000077"
     CDS             complement(134..1882)
                     /locus_tag="VQU30_000077"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000828810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET2446274.1"
                     /translation="MKRQTVNQTLKRLVVDLANHPFLLFLAFLGTIAQVGLSIYLPIL
                     IGQVIDQVLVAGSSPVFWQIFLQMLLVVIGNTLVQWANPLLYNRLIFSYTRDLRERII
                     HKLHRLPIAFADRQGNGEMVSRVTTDIEQLAAGLTMIFNQFFIGVLMILVSILAMLQI
                     HLLMTLLVLLLTPLSMVISRFIAKRSYHLFQKQTETRGIQTQLIEESLSQQTIIQSFN
                     AQTEFIQRLREAHDNYSGYSQSAIFYSSTVNPSTRFVNALIYALLAGVGAYRIMMGST
                     LTVGRLVTFLNYVQQYTKPFNDISSVLAELQSALACVERIYGVLDSPEVAETGKEVLT
                     SDQVKGAISFKHVSFGYHPEKILIKELSIDIPAGSKVAIVGPTGAGKSTLINLLMRFY
                     PISSGDILLDGQSIYDYTRVSLRQQFGMVLQETWLTQGTIHDNIAFGNPEASREQVIA
                     AAKAANADFFIQQLPQGYDTKLENAGESLSVGQAQLLTISRVFLAIPKILILDEATSS
                     IDTRTEVLVQDAFAKLMKGRTSFIIAHRLSTIQDADLILVLVDGDIVEYGNHQELMDR
                     KGKYYQMQKAAAFSSE"
     gene            complement(1884..3608)
                     /locus_tag="VQU30_000078"
     CDS             complement(1884..3608)
                     /locus_tag="VQU30_000078"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET2446275.1"
                     /translation="MKHLLSYFKPYIKESILAPLFKLLEAVFELLVPMVIAGIVDQSL
                     PQGDQGHLWMQIGLLLIFAVIGVLVALIAQFYSAKAAVGFAKELTNDLYRHILSLPKD
                     SRDRLTTSSLVTRLTSDTYQIQTGINQFLRLFLRAPIIVFGAIFMAYRISAELTFWFL
                     VMVAILTIVIVGLSRLVNPLYSSLRKKTDQLVQETRQQLQGMRVIRAFGQEKRELQIF
                     QTLNQVYARLQEKTGFLSSLLTPLTYLIVNGTLLVIIWQGYISIQGGVLSQGALIALI
                     NYLLQILVELVKLAMLINSLNQSYISAKRIEEVFAESPENIHSELEQKQVTSGRVLQV
                     QELTFTYPDAAQPSLRDISFDMTQGQILGIIGGTGSGKSSLVQLLLGLYPVDKGNIDL
                     YQNGRSPLNLEQWRSWIAYVPQKVELFKGTIRSNLTLGLNQEVTDQELWQALEIAQAK
                     DFVSDKEGLLDALVEAGGRNFSGGQKQRLSIARAVLRQAPFLILDDATSALDTITESK
                     LLKAIRENLPNMSLILISQRTSTLQMADQILLLEKGELLAVGKHDDLMKSSQVYREIN
                     ASQHGKED"
     gene            complement(3666..4604)
                     /gene="msrB"
                     /locus_tag="VQU30_000079"
     CDS             complement(3666..4604)
                     /gene="msrB"
                     /locus_tag="VQU30_000079"
                     /EC_number="1.8.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001865281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-methionine (R)-S-oxide reductase MsrB"
                     /protein_id="HET2446276.1"
                     /translation="MAEIYLAGGCFWGLEEYFSRISGVLETSVGYANGQVETTNYQLI
                     KETDHAETVQVIYDEKEVSLREILLYYFRVIDPLSINQQGNDRGRQYRTGIYYQDEAD
                     LPAIYTVVQEQERMLGRKIAVEVEQLRHYILAEDYHQDYLRKNPSGYCHIDVTDADKP
                     LIDAANYEKPSQEVLKASLSEESYRVTQEAATEAPFTNAYDQTFEEGIYVDITTGEPL
                     FFAKDKFASGCGWPSFSRPISKELIHYYKDLSHGMERIEVRSRSGSAHLGHVFTDGPR
                     ELGGLRYCINSASLRFVAKDEMEKAGYGYLLPYLNK"
     gene            complement(4746..4823)
                     /locus_tag="VQU30_000080"
                     /pseudo
     CDS             complement(4746..4823)
                     /locus_tag="VQU30_000080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002674100.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopuranose mutase"
     gene            complement(4899..5768)
                     /locus_tag="VQU30_000081"
     CDS             complement(4899..5768)
                     /locus_tag="VQU30_000081"
                     /EC_number="2.7.1.39"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000692406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="homoserine kinase"
                     /protein_id="HET2446277.1"
                     /translation="MKIIVPATSANIGPGFDSVGVAVTKYLQIEVCEERDEWLIEHQI
                     GKWIPHDERNLLLKIALQIVPDLQPRRLKMTSDVPLARGLGSSSSVIVAGIELANQLG
                     QLNLSDHEKLQLATKIEGHPDNVAPAIYGNLVIASSVEGQVSAIVADFPECDFLAYIP
                     NYELRTRDSRSVLPKKLSYKEAVAASSIANVAVAALLAGDMVTAGQAIEGDLFHERYR
                     QDLVREFAMIKQVTKENGAYATYLSGAGPTVMVLASHDKMPTIKAELEKQPFKGKLHD
                     LRVDTKGVRVEAK"
     gene            complement(5770..7056)
                     /locus_tag="VQU30_000082"
     CDS             complement(5770..7056)
                     /locus_tag="VQU30_000082"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="homoserine dehydrogenase"
                     /protein_id="HET2446278.1"
                     /translation="MTVKIALLGFGTVASGVPFLLKENGGKINQSAHSDIKVAKVLVK
                     DEDEKNRLLAAGNDFNFVTNVDDILSDQDITIVVELMGRIEPAKTFITRALEAGKHVV
                     TANKDLLAVHGAELLEIAQANKVALYYEAAVAGGIPILRTLANSLASDKITRVLGVVN
                     GTSNFMVTKMVEEGWSYDDALAEAQRLGFAESDPTNDVDGIDAAYKMVILSQFAFGMK
                     IAFDDVAHKGIRNITPEDVAVAQELGYVVKLVGSIEETSSGIAAEVTPTFLPKAHPLA
                     SVNGVMNAVFVESIGIGESMYYGPGAGQKPTATSVVADIVRIVRRLNDGTIGKDFNEY
                     SRDLVLANPEDVKANYYFSILALDSKGQVLKLAEIFNAQDISFKQILQDGKEGDKARV
                     VIITHKINKAQLENVSAELKKVSEFDLLNTFKVLGE"
     gene            complement(7207..7944)
                     /gene="mecA"
                     /locus_tag="VQU30_000083"
     CDS             complement(7207..7944)
                     /gene="mecA"
                     /locus_tag="VQU30_000083"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000782680.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adaptor protein MecA"
                     /protein_id="HET2446279.1"
                     /translation="MKMKQISDTTLKITMSLEDLMDRGMEIADFLVPQEKTEEFFYAI
                     LDELEMPDSFLDTGMLSFRVTPKPDKVDVFVTKSKIDQNLDFEDLSDLPDMEELAQMS
                     PDEFIKTLEKSIADKTKDDIEAIQSLEQVEAKEEEQEQAEQEAESKKEPYIYYILSFA
                     KLADLVAFAKTVTFEMETSELYKMNERYYLTILVDIENHPSPYPAWLLARMREFADDS
                     DISRSVLQEYGQVLMSHDAVLNLQKIG"
     gene            complement(8144..9178)
                     /locus_tag="VQU30_000084"
     CDS             complement(8144..9178)
                     /locus_tag="VQU30_000084"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000461501.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prephenate dehydratase"
                     /protein_id="HET2446280.1"
                     /translation="MFEHYSVADLFANLYKKRKANILALIALFALIAVPFTIKAVRNK
                     NTVKDTTSYSTYLIYKITPPKESAKTILNHQIGGYSDFYGKLIDGNLNGAYLFNDVEP
                     SELKKIASELDTTETTLKNSTNDYWWKKLTVYYMIDDAGVGVKILTSSKDANDLLEKK
                     IDGLIEKFKHAYANVKIEKLETINSKELNANGETALGLNVKNLILRLVVIGVVCVILV
                     VMGNVLVYLFNPTINRVGDFSQYQIDFVTEITTIANLADVLSYKNTGQELTIVSSNKA
                     ILDKLKQSQEALKGMHFVDLQDVSSLLERDTVLLVEEYGVTRYKKFEQSLQILRNLNR
                     SILGVATFKL"
     gene            complement(9207..10640)
                     /locus_tag="VQU30_000085"
     CDS             complement(9207..10640)
                     /locus_tag="VQU30_000085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000565082.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="O-antigen polysaccharide polymerase Wzy family
                     protein"
                     /protein_id="HET2446281.1"
                     /translation="MIDGKRLLFSLTIVSYALTLVSGIVYLFNNNNVSLLSTLLFLLV
                     SSLIACWNDIKYYLIHFIFYLTIFVFLVSRPTIDYFRDGALDTYHPIAYRFAFIVVMV
                     SILGLTTGGILARYFIARKKIKVANIGNSLKEVYIKRLRFVSLGVFLLTYPFYFIRLF
                     ERLLYRLQTSYYAYYANFESKLPYFTYILSTFTVYAMCMYLATKPKKLQATAVLVSFI
                     AANTIHLAIGTRNPFILSILFAFVYYFMREQTEKGKWIGFKEKLAIFVGSPILMLAMG
                     VLNYVRDNVQVSHTGFWDILLDFIYKQGTSFGVLARGFLFNSSLPYRDFRNFTFGPVL
                     DYFARGSLGAIFGGKAFEHTTNSVELAIDSNSYAHNLSYLVLNKEYLKGHGIGSSYIM
                     ELYTDYGMIGVFLLSFLLGVLFIAMLQVAYRSRTILFALSLLILNNLFFMPRSSFSES
                     FFNLFTMQFWGIVLVIIFIAKMLTKEN"
     gene            complement(10656..11642)
                     /locus_tag="VQU30_000086"
     CDS             complement(10656..11642)
                     /locus_tag="VQU30_000086"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000446977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HET2446282.1"
                     /translation="METALISVIVPVYNVAQYLEKSIASIQKQIYQNLEIILVDDGAT
                     DESGRLCDSIAEQDDRVSVLHKKNEGLSQARNDGMKQAHGDYLIFIDSDDYIHPEMIQ
                     SLYEQLVQEDADVSSCGVMNVYANDESPQSANQDDYFVCDSQTFLKEYLIGEKIPGTI
                     CNKLIKRQIATALSFPKGLIYEDAYYHFDLIKLAKKYVVNTKPYYYYFHRGDSITTKP
                     YAEKDLAYIDIYQKFYNEVVKNYPDLKEVAFFRLAYAHFFILDKMLLDDQYKQFEAYS
                     QIHRFLKGHAFAISRNPIFRKGRRISALALFINISLYRFLLLKNIEKSKKLH"
     gene            complement(11644..12747)
                     /locus_tag="VQU30_000087"
     CDS             complement(11644..12747)
                     /locus_tag="VQU30_000087"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000225894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HET2446283.1"
                     /translation="MVAKKKILFFMWSFSLGGGAEKILSTIVSNLDLEKYDIDILEME
                     HFDKGYESVPKHVRILKSLQDYRQTRWLRAFLWRMRIYFPRLTRRLLVKDDYDVEVSF
                     TIMNPPLLFSKRREVKKISWIHGSIEELLKDSSKRESHRSQLDAANTIVGISKKTSNS
                     IKEVYPDYASKLQIIYNGYDFQTILEKSQEKIDIEIAPQSICTIGRIEENKGSDRVVE
                     VIRLLHQEGKNYHLYFIGAGDMEEELKKRVKEYGIEDYVHFLGYQKNPYQYLSQTKVL
                     LSMSKQEGFPGVYVEALSLGLPFISTDVGGAEELSQEGRFGQIIESNQEAAQAITNYM
                     TSASNFDVDEASQFIQQFTITKQIEQVEKLLEE"
     gene            complement(12737..13582)
                     /locus_tag="VQU30_000088"
     CDS             complement(12737..13582)
                     /locus_tag="VQU30_000088"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001061982.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphorylcholine transferase LicD"
                     /protein_id="HET2446284.1"
                     /translation="MNNMTDLKAIQARSLEMAEYFVAFCKEHDLLCYLCGGGAIGALR
                     NKGFIPWDDDLDFFMPRKDYEKLAELWPRYADERYFLSKSHKDFVDRNLFITIRDKET
                     TCIKPYQQDLDLPHGLTLDVLPLDYYPKNPAERKKQVRWALIYSLFCAQTIPEKHGAL
                     MKWGSRILLGLTPKSLRYRIWKKAEKEMTKYDLADCDGITELCSGPGYMRNKYPITSF
                     EDNLFLPFEGTEMPIPIGYDVYLRTAFGDYMTPPPADKQVPHHDAVIADMDKSYTEYK
                     GEYGG"
     gene            complement(13861..15135)
                     /gene="psr"
                     /locus_tag="VQU30_000089"
     CDS             complement(13861..15135)
                     /gene="psr"
                     /locus_tag="VQU30_000089"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000032347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyisoprenyl-teichoic acid--peptidoglycan
                     teichoic acid transferase Psr"
                     /protein_id="HET2446285.1"
                     /translation="MSKENPLSHHEQLRYDYLLKNIHYLNEREKNEFAYLQEKLTLAR
                     GNSSSSLEQEREEQVDLPSYANRSRSQSKSQALSFPPKKKRRKLRLKRIFMVIFSLLV
                     CVALAMVFMFLRGYQDASAKKTADARAAQVEVFNGQDTRDGVNILIMGTDGRIGQNSV
                     ETRTDSIMVLNVGGSDKKMKLVSFMRDNLVYIDGYSQVINGRKQTDNKLNVAYELGEQ
                     EGQKGAEMVRQVLKDNFDLDIKYYALVDFQAFATAIDTLFPDGVTIDAQFSTLNGRPL
                     TEATVGDDLYATETESPTQTIKVGKQQMNGSTLLNYARFRDDDEADYGRTKRQQQVLT
                     AILEQIKDPTKLFTGSEALGKVFAMTSTNVPYTFLLTNGLSVLDGAKNGIEKLTIPEL
                     GDWVDAYDVYGGLGLLVDQNKYQTKLAQMGLR"
     gene            complement(15132..15980)
                     /gene="pheA"
                     /locus_tag="VQU30_000090"
     CDS             complement(15132..15980)
                     /gene="pheA"
                     /locus_tag="VQU30_000090"
                     /EC_number="4.2.1.51"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001865057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prephenate dehydratase"
                     /protein_id="HET2446286.1"
                     /translation="MKIAYLGPKGSFSHHVVQTAFPHEELQAFANITDVIKAYEQGLV
                     DYSVVPVENSIEGSVHETLDYLFHQAHIQAVAEIVQPIHQQLMVVPGHTKIEKIFSHP
                     QALAQGKKFIDEQYPEAQIEVTASTAYAARFISEHPDQPFAAVAPRSSAEEYGLELIA
                     EDIQEMEANFTRFWVLGAEKPSIPLQAQTEKMSLALTLPDNLPGALYKALSTFAWRGI
                     DLTKIESRPLKTALGEYFFIIDVDYIDKDLVHFAQKELEAIGIQYKILGAYPIYPISD
                     HGKERR"
     gene            complement(15977..16453)
                     /locus_tag="VQU30_000091"
     CDS             complement(15977..16453)
                     /locus_tag="VQU30_000091"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397876.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="shikimate kinase"
                     /protein_id="HET2446287.1"
                     /translation="MAKVLLGFMGAGKSTIARGLDPNYLDMDALIEKRLGMSIANFFA
                     EKGEAAFRHVESEVLADLLQTDQVVSTGGGVVISQRNRDLLKTNTDNIYLKADFETLY
                     LRIAADKDNQRPLFLNNSKEELVAIFQERQAWYEEVASRVLDVTKLSPEEIIEELR"
     gene            complement(16446..17729)
                     /gene="aroA"
                     /locus_tag="VQU30_000092"
     CDS             complement(16446..17729)
                     /gene="aroA"
                     /locus_tag="VQU30_000092"
                     /EC_number="2.5.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004236106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-phosphoshikimate 1-carboxyvinyltransferase"
                     /protein_id="HET2446288.1"
                     /translation="MKLKTNIRHLHGSIRVPGDKSISHRSIIFGSLAEGETKVYDILR
                     GEDVLSTMQVFRDLGVEIEDKDGVITIQGVGMAGLKAPQNALNMGNSGTSIRLISGVL
                     AGADFEVEMFGDDSLSKRPMDRVTLPLKKMGVSISGQTERDLPPLRLKGTKNLRPIHY
                     ELPIASAQVKSALMFAALQAKGESVIIEKEYTRNHTEDMLQQFGGHLSVDGKKITVQG
                     PQKLTGQKVVVPGDISSAAFWLVAGLIAPNSRLVLQNVGINETRTGIIDVIRAMGGKL
                     EITEIDPVAKSATLIVESSDLKGTEIGGALIPRLIDELPIIALLATQAQGVTVIKDAE
                     ELKVKETDRIQVVADALNSMGADITPTADGMIIKGKSALHGARVNTFGDHRIGMMTAI
                     AALLVADGEVELDRAEAINTSYPSFFDDLESLIHG"
     gene            complement(17821..18159)
                     /locus_tag="VQU30_000093"
     CDS             complement(17821..18159)
                     /locus_tag="VQU30_000093"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000065990.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlbF/YmcA family competence regulator"
                     /protein_id="HET2446289.1"
                     /translation="MSNIYDSANELSRGLRGLPEYKAVKAAKDAIAADAEASKIFTEY
                     LAFQEEIQKLAQTGQMPDASFQAKMEGFGKQIQGNSLLSEFFTKQQQLAIYLSDIEKI
                     VFEPVSELLK"
     gene            complement(18170..19273)
                     /locus_tag="VQU30_000094"
     CDS             complement(18170..19273)
                     /locus_tag="VQU30_000094"
                     /EC_number="1.3.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001140485.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prephenate dehydrogenase"
                     /protein_id="HET2446290.1"
                     /translation="MAKTIYIAGLGLIGASMALGIKRDHPDYEILGYNRSQASRDIAL
                     KEGMIDRATDDFASFAPLADVIILSLPIKQTIAFIKELANLDLREGVIISDAGSTKST
                     IVDAAEQYLAGKSVRFVGAHPMAGSHKTGAASADVNLFENAYYIFTPSSLTSQDTLKE
                     MKDLLSGLHARFIEIDAKEHDRVTSQISHFPHILASSLMEQTAVYAQEHEMARRFAAG
                     GFRDMTRIAESEPGMWTSILLSNSETILDRIEDFKERLEVIGQAISKGDEEQIWNFFN
                     QAREQRQTMEIHKRGGVDSSYDLYVDVPDEEDVILRILELLRGTSLVNIHINEENRED
                     IHGILQISFKNAQDLERAEHLITENTDYTVVIK"
     gene            complement(19283..20449)
                     /gene="aroC"
                     /locus_tag="VQU30_000095"
     CDS             complement(19283..20449)
                     /gene="aroC"
                     /locus_tag="VQU30_000095"
                     /EC_number="4.2.3.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004259785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chorismate synthase"
                     /protein_id="HET2446291.1"
                     /translation="MRYLTAGESHGPRLTAIIEGIPAGLPLTAEDINEDLRRRQGGYG
                     RGGRMKIESDQVVFTSGVRHGKTTGAPITMDVINKDHQKWLDIMSAEDIEDRLKSKRK
                     ITHPRPGHADLVGGIKYRFDDLRNSLERSSARETTMRVAVGAVAKRLLAELDMEIANH
                     VVVFGGKEIDVPENLTVAEIKQRAAQSEVSIVNQEREQEIKDYIDQIKRDGDTIGGVV
                     ETVVGGVPVGLGSYVQWDRKLDARLAQAVVSINAFKGVEFGLGFEAGYRKGSQVMDEI
                     LWSKEDGYTRRTNNLGGFEGGMTNGQPIVVRGVMKPIPTLYKPLMSVDIETHEPYKAT
                     VERSDPTALPAAGMVMEAVVATVLAQEILEKFSSDNLEELKEAVAKHRDYTKNY"
     gene            complement(20459..21526)
                     /locus_tag="VQU30_000096"
     CDS             complement(20459..21526)
                     /locus_tag="VQU30_000096"
                     /EC_number="4.2.3.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308136.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-dehydroquinate synthase"
                     /protein_id="HET2446292.1"
                     /translation="MKIRIDIPHHPYDIQIEKGCMAQAGQWLRELWQPQKVVIVTDNH
                     VASLYAEKVKLSLEDAGFQVAVFDFLEGEERKNLTTVQKVYEFLVKQGLTRSDGIVAL
                     GGGVVGDLAGFVASTYMRGIHFVQIPTSLTAQVDSSIGGKTGVNTPFAKNMVGTFAQP
                     DGVLIDPLVLETLGKRELIEGMGEVIKYGLIEDPELWALLTGLNGSVESILEHAETLI
                     EHSCQVKRKMVVEDELDNGIRLYLNFGHTIGHAIEATAGYGKVMHGEAVAMGMVQISK
                     VAEEKGLMPAGITQSITEMCQKFGLPVDYENWKVDKLYQALTHDKKARGNTLKLVLVP
                     ELGSATIHPVSLEEMKDYLVK"
     gene            complement(21545..22399)
                     /locus_tag="VQU30_000097"
     CDS             complement(21545..22399)
                     /locus_tag="VQU30_000097"
                     /EC_number="1.1.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004258171.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="shikimate dehydrogenase"
                     /protein_id="HET2446293.1"
                     /translation="MKLDGYTRLAAVVANPIKHSISPFIHNRAFEATATNGAYVAWEI
                     EASDLVETVANIRRYQMFGINLSMPYKEQVIPYLDELSDEARLIGAVNTVVNENGNLI
                     GYNTDGKGFFKCLPSFTISGKKMTLLGAGGAAKSILAQAILDGVSQISVFVRSVSMEK
                     TRPYLDKLQEQTGFKVDLCALEYVSELQARIAESDLLVNATSVGMDGQSSPVPENIVL
                     PETLLVADIIYQPFETPFLKWARSQGNPAVNGLGMLLYQAAEAFQLWTGKKMPTEEIW
                     QSLTEKYQ"
     gene            complement(22389..23066)
                     /locus_tag="VQU30_000098"
     CDS             complement(22389..23066)
                     /locus_tag="VQU30_000098"
                     /EC_number="4.2.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000780376.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I 3-dehydroquinate dehydratase"
                     /protein_id="HET2446294.1"
                     /translation="MKLIVSVMPRSLEEAQALDATRYLDADIIEWRADYLPKEAILQV
                     APAIFEKFAGRELVFTLRTRSEGGEIDLSPEEYIHLIKEVAQLYQPDYIDFEYYSYKD
                     VFEEMLDFPNLVLSYHNFQETPENMMEILSELTILNPKLVKVAVMAHTEQDVLDLMNY
                     TRGFKTLNPEQEYVTISMGKVGKVSRITADVTGSSWSFASLDEVSAPGQISLASMKKI
                     REILDEA"
     gene            complement(23063..24226)
                     /locus_tag="VQU30_000099"
     CDS             complement(23063..24226)
                     /locus_tag="VQU30_000099"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001837533.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent rRNA methyltransferase"
                     /protein_id="HET2446295.1"
                     /translation="MNRIRVSKRVEKKLAKGLVLLEASDLENVNLKDQEVEVQGQEGN
                     FLGTAYLSQQNKGLGWFVSKDKVAFNQAFFETLFRKAKEKRNAYYQDDLTTAFRLFNQ
                     EGDGFGGLTVDLYGDYAVFSWYNSYVYQIRQTISEAFRQVFPEVLGAYEKIRFKGLDY
                     ESAHVYGQEAPDFFTVLENGVLYQVFMNDGLMTGIFLDQHEVRGSLVDGLAMGKSLLN
                     MFSYTAAFSVAAAMGGASQTTSVDLAKRSRELSQAHFQANGLSTDERRFIVMDVFEYF
                     KYAKRKNLTYDVIVLDPPSFARNKKQTFSVAKDYHKLISQSLEILNPGGIIIASTNAA
                     NVSRQKFTEQIDKGFAGRSYQILNKYGLPADFAYNKKDESSNYLKVISMKVSK"
     gene            complement(24911..26545)
                     /locus_tag="VQU30_000100"
                     /pseudo
     CDS             complement(24911..26545)
                     /locus_tag="VQU30_000100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001237556.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(26526..27275)
                     /locus_tag="VQU30_000101"
     CDS             complement(26526..27275)
                     /locus_tag="VQU30_000101"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000569185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET2446296.1"
                     /translation="MIEFQNVSKLYGDKEALSNLNLQIENGEIMGLIGHNGAGKSTTI
                     KSLVSIISPSSGRILVDGQELSENRLAIKRKIGYVADSPDLFLRLTANEFWELIASSY
                     DLTSSDLETSLARLLNVFDFAENRYQVIETLSHGMRQKVFVIGALLSAPDIWVLDEPL
                     TGLDPQAAFDLKQMMKEHAQKGKTVLFSTHVLEVAEQVCDRIAILKKGHLIYCGSVEN
                     LRKDHPDQFLESIYLSLAGRKEEVADASQGH"
     gene            27454..28908
                     /locus_tag="VQU30_000102"
     CDS             27454..28908
                     /locus_tag="VQU30_000102"
                     /EC_number="3.2.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001181079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-amylase"
                     /protein_id="HET2446297.1"
                     /translation="MQNQTLMQYFEWYLPHDGQHWTRLAENAPHLAHLGISHVWMPPA
                     FKATNEKDVGYGVYDLFDLGEFNQKGTVRTKYGFKEDYLQAIQALKEQGIQPMADVVL
                     NHKAAADNREAFQVIEVDPVDRTVELGEPFTINGWTSFTFDGRQDTYNGFHWHWYHFT
                     GTDYDAKRSKSGIYLIQGDNKGWANEELVDNENGNYDYLMYADLDFKHPEVIQNIYDW
                     ADWFMETTGVAGFRLDAVKHIDSFFMRNFIRDMKEKYGDDFYVFGEFWNPDKEANLDY
                     LEKTEEHFDLVDVRLHQNLFEASQAGANYDLRGIFTDSLVELKPDKAVTFVDNHDTQR
                     GQALESTVEEWFKPAAYALILLRQDGLPCVFYGDYYGISGQYAQEDFKEILDRLLAIR
                     KDLAYGEQNDYFDHANCIGWVRSGAENQSPIAVLISNDQENSKSMFVGQEWTNQTFVD
                     LLGNHQGQVTIDEEGYGQFPVSARSVSVWAVNTI"
     gene            complement(28998..31616)
                     /gene="alaS"
                     /locus_tag="VQU30_000103"
     CDS             complement(28998..31616)
                     /gene="alaS"
                     /locus_tag="VQU30_000103"
                     /EC_number="6.1.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012130635.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alanine--tRNA ligase"
                     /protein_id="HET2446298.1"
                     /translation="MKQLSSAQVRQMWLDFWATKGHSVEPSVSLVPVNDPTLLWINSG
                     VATLKKYFDGTIIPENPRITNAQKAIRTNDIENVGKTARHHTMFEMLGNFSIGDYFRD
                     EAITWAYELLISPEWFDFPAEKLYMTYYPDDKDSYNRWIEVGVDPSHLIPIEDNFWEI
                     GAGPSGPDTEIFFDRGEAFDPENIGLRLLAEDIENDRYIEIWNIVLSQFNADPAVPRS
                     EYKELPHKNIDTGAGLERLVAVIQGAKTNFETDLFMPIIREVEKLSGKVYDQDGDNMS
                     FKVIADHIRSLSFAIGDGALPGNEGRGYVLRRLLRRASMHGQKLGINEPFLYKLVPTV
                     GKIMESYYPEVLEKRDFIEKIVKSEEESFARTLHSGQHFAQGIVADLKEKGQSVIAGS
                     DVFKLYDTYGFPVELTEEIAEEAGMTVDREGFEAAMKEQQERARASAVKGGSMGMQNE
                     TLQNITVESVFNYNTSQLSSKLVAIVADNAEVGAVSEGTASLIFAETSFYAEMGGQVA
                     DYGQILDESGKIVATVTNVQKAPNGQALHTVEVLAPLALNQEYTLAIDSNRRHRVMKN
                     HTATHLLHAALHNILGNHATQAGSLNEVEFLRFDFTHFQAVTAEELRAIEQQVNEKIW
                     EALEVKTVETDIDTAKEMGAMALFGEKYGKEVRVVTIGDYSIELCGGTHVGNTSEIGL
                     FKIVKEEGIGSGTRRILAVTGKEAFEAYREQEDALKAVAATLKAPQVKEVPHKVEGLQ
                     EQLRQLQKENAELKEKAAAAAAGDIFKDAKEVNGHRYIASQVSVSDAGALRTFADNWK
                     QKDYSDLLVLVAAIGDKVNVLVASKTKDLHAGNLVKELAPIIDGRGGGKPDMAMAGGS
                     NQAKIQELLDAVAGKL"
     gene            complement(31638..32123)
                     /locus_tag="VQU30_000104"
     CDS             complement(31638..32123)
                     /locus_tag="VQU30_000104"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000847073.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LURP-one-related family protein"
                     /protein_id="HET2446299.1"
                     /translation="MKTFLVKQKFRLGGERFAIKDDRGEIAYQVEGSFFKIPKTFTIY
                     DAAGEQVSQISKEILTLLPRFEIQLLDGSSFVIRKKLTFWRDKYEFDNLGLRIEGNIW
                     DLNFKLLDDRDQLIAEIKKELFHLTSTYTVTVLEDAYADLVISLCVAIDYVEMLESQS
                     H"
     gene            complement(32398..32637)
                     /locus_tag="VQU30_000105"
     CDS             complement(32398..32637)
                     /locus_tag="VQU30_000105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000784186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2446300.1"
                     /translation="MKMSTFFNKSFWPTFMIVNQTAILFHLKDGLDRQYLTTESIYWV
                     IGTFIFGNILVAVFSNMKIWDKKKNGSKKKYILEK"
     gene            complement(32890..33960)
                     /locus_tag="VQU30_000106"
     CDS             complement(32890..33960)
                     /locus_tag="VQU30_000106"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000725675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HET2446301.1"
                     /translation="MKKIYSFLAGIAAIILVLWGIATHLDSKINSRDSQKLVIYNWGD
                     YIDPELLTQFTEETGIQVQYETFDSNEAMYTKIKQGGTTYDIAIPSEYMINKMKDEDL
                     LVPLDYSKIEGIENIGPEFLNQSFDPGNKFSIPYFWGTLGIVYNETMVDEAPEHWDDL
                     WKPEYKNSIMLFDGAREVLGLGLNSLGYSLNSKDLQQLEETVDKLYKLTPNIKAIVAD
                     EMKGYMIQNNVAIGVTFSGEASQMLEKNENLRYVVPTEASNLWFDNMVIPKTVKNQDS
                     AYAFINFMLKPENALQNAEYVGYSTPNIPAKELLPEETKEDKAFYPDVETMKHLEIYE
                     KFDHKWTGKYSDLFLQFKMYRK"
     gene            complement(33957..34730)
                     /locus_tag="VQU30_000107"
     CDS             complement(33957..34730)
                     /locus_tag="VQU30_000107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398754.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HET2446302.1"
                     /translation="MKKFANLYLGLVFLVLYLPIFYLIGYAFNAGDDMNSFTGFSWTH
                     FETMFGDGRLMLILAQTFFLAFLSALIATIIGTFGAIYIYQSRKKYQEAFLSLNNILM
                     VAPDVMIGASFLILFTQLKFSLGFLTVLSSHVAFSIPIVVLMVLPRLKEMNGDMIHAA
                     YDLGASQFQMFKEIMLPYLTPSIITGYFMAFTYSLDDFAVTFFVTGNGFSTLSVEIYS
                     RARKGISLEINALSALVFLFSIILVVGYYFISREKEEQA"
     gene            complement(34727..35533)
                     /locus_tag="VQU30_000108"
     CDS             complement(34727..35533)
                     /locus_tag="VQU30_000108"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398755.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HET2446303.1"
                     /translation="MKKTSSKLFVVPYMLWIALFVLAPLVLIFGQSFFNIEGQFSLEN
                     YKSYFASQNLTYLKMSFNSVLYAGIVTFVTLLISYPTALFLTRLKHRQLWLMLIILPT
                     WINLLLKAYAFIGIFGQNGSINQFLEFIGIGSQQLLFTDFSFIFVASYIELPFMILPI
                     FNVLDDMDNNLINASYDLGATKWETFRHVIFPLSMNGVRSGVQSVFIPSLSLFMLTRL
                     IGGNRVITLGTAIEQNFLTNDNYGMGSTIGVILILTMFITMWVTKERRER"
     gene            complement(35514..36671)
                     /locus_tag="VQU30_000109"
     CDS             complement(35514..36671)
                     /locus_tag="VQU30_000109"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018372333.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET2446304.1"
                     /translation="MKKPIIEFKNVSKVFEDSNTKVLKDINFELEEGKFYTLLGASGS
                     GKSTILNIIAGLLDATTGDIMLDGVRINDIPTNKRDVHTVFQSYALFPHMNVFENVAF
                     PLRLRKIDKKEIEQRVAEVLKMVQLEGYEKRSIRKLSGGQRQRVAIARAIINQPRVVL
                     LDEPLSALDLKLRTDMQYELRELQQRLGITFVFVTHDQEEALAMSDWIFVMNDGEIVQ
                     SGTPVDIYDEPINHFVATFIGESNILPGTMIEDYLVEFNGKRFEAVDGGMKPNEPVEV
                     VIRPEDLRITLPEEGKLQVKVDTQLFRGVHYEIIAYDELGNEWMIHSTRKAIVGEEIG
                     LDFESEDIHIMRLNETEEEFDARIEEYVEIEEQEAGLINAIEEERDEENKL"
     gene            complement(36730..37680)
                     /gene="murB"
                     /locus_tag="VQU30_000110"
     CDS             complement(36730..37680)
                     /gene="murB"
                     /locus_tag="VQU30_000110"
                     /EC_number="1.3.1.98"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000116191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramate dehydrogenase"
                     /protein_id="HET2446305.1"
                     /translation="MSVREKMLEILEGIDIRFQEPLHSYSYTKVGGEADYLVFPRNRF
                     ELARLVKFANQENIPWMVLGNASNIIVRDGGIRGFVILCDKLNNVSVDGYTIEAEAGA
                     NLIETTRIALRHSLTGFEFACGIPGSVGGAVFMNAGAYGGEIAHILQSCKVLTKDGEI
                     ETLSAKDLAFGYRHSAIQESGAVVLSVKFALAPGTHQVIKQEMDRLTHLRELKQPLEY
                     PSCGSVFKRPVGHFAGQLISEAGLKGYRIGGVEVSEKHAGFMINVADGTAKDYEDLIQ
                     SVIEKVKEHSGITLEREVRILGESLSVAKMYAGGFTPCKR"
     gene            complement(37792..38544)
                     /locus_tag="VQU30_000111"
     CDS             complement(37792..38544)
                     /locus_tag="VQU30_000111"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000152219.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhfC family intramembrane metalloprotease"
                     /protein_id="HET2446306.1"
                     /translation="MTIHIIITMLLLLAFLIGSIWFAKKKYQINLAVLGLGAVAFFVS
                     SQILEKLVHILILHPQKDGSIALLQDHPLIYIIYGLAMAAFFEETARLVFFKWFEKKR
                     SLEKADALAYGLGHGGLELIFLGLTSLLNLYIVLSAVQTQNPQVMQLLSENMLKTIQS
                     LSVWQIYLLGFERILALGFQLLLTVWVYQAVRQKKWIYLLTAYGLHAFFDLAPSLFQV
                     GWLTNPVLVEVILALELVLVAYGTKEIFCKKS"
     gene            complement(38554..39285)
                     /gene="budA"
                     /locus_tag="VQU30_000112"
     CDS             complement(38554..39285)
                     /gene="budA"
                     /locus_tag="VQU30_000112"
                     /EC_number="4.1.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000360290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetolactate decarboxylase"
                     /protein_id="HET2446307.1"
                     /translation="MDKNVQEPVKLFQYNTLGALMAGLYGGTMTVGELLEHGDLGLGT
                     LDSIDGELIVLDGKAYQAKGSGDQPEIVEVSPDALIPYAAVVPHQAEVIFRQRFEMTD
                     KELKERIESYYDGENLFRSIKIRGEFLHMHVRMIPKSTPDTKFADVATHQPEYSRDNV
                     AGTIVGFWTPEIFHGVSVAGYHLHFISDDLTFGGHVMDFVIKEGIIEVGAVDQLDQRF
                     PVQDRQYLFAKFNVDEMKKDIEKAE"
     gene            39427..40698
                     /locus_tag="VQU30_000113"
     CDS             39427..40698
                     /locus_tag="VQU30_000113"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PLP-dependent aminotransferase family protein"
                     /protein_id="HET2446308.1"
                     /translation="MKKQSKYKEVVSYLKNGIESGRFPTGSRLPSIRQLSLDFHCSKD
                     TIQRALLELRHEQYLYAKPQSGYYVLEQGQHQDLEIEVTDEHASAYDDFRLCVNETLI
                     GRENYLFNYYDNQEGLEDLRQSIHKLLFEQALYCKANQLVLTSGTQQALFILSQISFP
                     RQAKEILVEQPTYHRMNRLLIAQGLDYQTIERGIDGIDLEELEGHFKTGKIKFFYTIP
                     RFHYPLGHSYSEQDKRSILNLAAKYDVYIVEDDYLGDLDSKKGQTFHYLDTEEHVIYI
                     KSFSTSLFPALRITALILPNAIKEAFVAYKNILDYDSNLIMQKALSLYIDSQLFEKNR
                     LARLTNHESYQKQIEERITKTPCPLPHYPLHDGLLLDLRQYPKIASLKHSQLGLDFFE
                     EAYLSTCPYQFAKVSLDNLENVLNYLKAELE"
     gene            complement(40718..41533)
                     /locus_tag="VQU30_000114"
     CDS             complement(40718..41533)
                     /locus_tag="VQU30_000114"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000837371.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transporter substrate-binding domain-containing
                     protein"
                     /protein_id="HET2446309.1"
                     /translation="MKSKKWIFVLCNFLASFFLVACQSGSNGSQSAVEAIKQKGKLVV
                     ATSPDYAPFEFQSLVDGKNQVVGADIDMAQAIADELGVKLEILSMSFDNVLTSLQTGK
                     ADLAVAGISATDERKEVFDFSIPYYENKISFLVRKADVEKYKDLTSLESANIAAQKGT
                     VPESMVKEQLPKAQLTSLTNMGEAVNELQAGKIDAVHMDEPVALSYAAKNAGLAVATV
                     SLKMKDGDANAVALRKNSDDLKEVVDKVIQKLKDEGTYQSYLEKAASLTEVEE"
     gene            complement(41690..42343)
                     /gene="phoU"
                     /locus_tag="VQU30_000115"
     CDS             complement(41690..42343)
                     /gene="phoU"
                     /locus_tag="VQU30_000115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000946475.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate signaling complex protein PhoU"
                     /protein_id="HET2446310.1"
                     /translation="MLRSQFEEDLEKLHNQFYAMGQEVLSQINRTVRAFVTHDRDLAK
                     EVIEDDAEVNEYEVKLEKKSFEMIALQQPVSQDLRTVLTVLKAVSDVERMGDHAVAIA
                     QATIRMKGEERIPAVEEEIKKMGREVKSVVEAALDLYLNGSVDDAYRVASMDEQINHY
                     FETIRDLATEEIKKNPEAIVTGRDYFQVISYLERIGDYAKNICEWVVYFETGKIVEL"
     gene            complement(42355..43113)
                     /gene="pstB"
                     /locus_tag="VQU30_000116"
     CDS             complement(42355..43113)
                     /gene="pstB"
                     /locus_tag="VQU30_000116"
                     /EC_number="7.3.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014713134.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter ATP-binding protein"
                     /protein_id="HET2446311.1"
                     /translation="MTDAILQVSDLSVYYNKKKALNSVSLSFQPKEITALIGPSGSGK
                     STLLKSLNRMGDLNPEVTTTGSVVYNGHNIYSPRTDTVELRKEIGMVFQQPNPFPMTI
                     YENVVYGLRINGIKDKQVLDEAVEKALQGASIWDEVKDRLYDSAIGLSGGQQQRVCVA
                     RVLATSPKIILLDEPTSALDPISAGKIEETLYGLKDKYTMLLVTRSMQQASRISDKTG
                     FFLDGDLIEFNDTKQMFLDPQHKETEDYITGKFG"
     gene            complement(43126..43929)
                     /gene="pstB"
                     /locus_tag="VQU30_000117"
     CDS             complement(43126..43929)
                     /gene="pstB"
                     /locus_tag="VQU30_000117"
                     /EC_number="7.3.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000852852.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter ATP-binding protein"
                     /protein_id="HET2446312.1"
                     /translation="MSTYNWDEKHILTFPEEKVALSTKDVHVYYGKNESIKGIDMQFE
                     RNKITALIGPSGSGKSTYLRSLNRMNDTIDIAKVTGQILYRGIDVNRPEINVYEMRKH
                     IGMVFQRPNPFAKSIYRNITFAHERAGVKDKQVLDEIVETSLRQAALWDQVKDDLHKS
                     ALTLSGGQQQRLCIARAISVKPDILLMDEPASALDPIATMQLEETMFELKKNFTIIIV
                     THNMQQAARASDYTGFFYLGDLIEYDKTATIFQNAKLQSTNDYVSGHFG"
     gene            complement(43940..44824)
                     /gene="pstA"
                     /locus_tag="VQU30_000118"
     CDS             complement(43940..44824)
                     /gene="pstA"
                     /locus_tag="VQU30_000118"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009443446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease PstA"
                     /protein_id="HET2446313.1"
                     /translation="MRAKKLDKLATAVLYTIASIIVTILASLILYILVRGLPHISWSF
                     LTGRSSAFQAGGGIGIQLYNSFFLLVITLIISVPLSMGAGIYLAEYAKKGPVTNFVRT
                     CIEILSSLPSVVVGLFGYLIFVVQFEYGFSIISGALALTVFNLPQMTRNVEDSLKHVH
                     HTQREAGLALGISRWETVVHVVIPEALPGIVTGVVLASGRIFGEAAALIYTAGQSAPA
                     LDWSNWNILSVTSPISIFRQAETLAVHIWKVNSEGTIPDGTIVSAGSAAVLLIFILIF
                     NFGARKFGSYLHKKLTAA"
     gene            complement(44814..45731)
                     /gene="pstC"
                     /locus_tag="VQU30_000119"
     CDS             complement(44814..45731)
                     /gene="pstC"
                     /locus_tag="VQU30_000119"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018378778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease subunit PstC"
                     /protein_id="HET2446314.1"
                     /translation="MNQEELAKKMLLPSKNSRLEKLGKGLTFACLSLIVILVAMILVF
                     VAQKGLSTFFVNGVNIFDFLLGGTWNPSSKEFGALPMILGSFIVTILSALIATPFAIG
                     AAVFMTEVSPKGAKILQPAIELLVGIPSVVYGFIGLQVVVPFVRSVFGGTGFGILSGI
                     SVLFVMILPTVTFMTTDSLRAVPRYYREASFAMGATRWQTIWRVILKAARSGIFTAVV
                     FGMARAFGEALAIQMVVGNSAVIPTSLTTPAATLTSILTMGIGNTVMGTVNNNVLWSL
                     ALVLLLMSLVFNSVIKLITKERGKKNYAR"
     gene            complement(45731..46609)
                     /gene="pstS"
                     /locus_tag="VQU30_000120"
     CDS             complement(45731..46609)
                     /gene="pstS"
                     /locus_tag="VQU30_000120"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000746338.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter substrate-binding
                     protein PstS"
                     /protein_id="HET2446315.1"
                     /translation="MKKRKKLALSLIAFWLTACLVGCASWIDRGESITAVGSTALQPL
                     VEVAADEFGTIHVGKTVNVQGGGSGTGLSQVQSGAVDIGNSDVFAEEKDGIDASALVD
                     HKVAVAGLALIVNKEVDVDNLTTEQLRQIFIGEVTNWKEVGGKDLPISVINRAAGSGS
                     RATFDTVIMEGQSAMQSQEQDSNGAVKSIVSKSPGAISYLSLTYIDDSVKSMKLNGYD
                     LSPENISSNNWPLWSYEHMYTLGQPNELAAEFLNFVLSDETQEGIVKGLKYIPIKEMK
                     VEKDAAGTVTVLEGRQ"
     gene            complement(47183..48487)
                     /locus_tag="VQU30_000121"
     CDS             complement(47183..48487)
                     /locus_tag="VQU30_000121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001160253.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RsmF rRNA methyltransferase first C-terminal
                     domain-containing protein"
                     /protein_id="HET2446316.1"
                     /translation="MKFPEGFVEKYKEILGDEARDFLASFEEEAVSAFRVNPLKEEQL
                     SFSDAITQTPWGHYGKVSGKSPEHATGLVYSQEPAAQMVAQVAQPSPGMKVLDLAAAP
                     GGKSTQLAAYLAGEGLLVSNEISSKRAKILVENMERFGATNVVVTNESADRLVKVFKG
                     YFDLIVLDAPCSGEGMFRKQPDAMDYWSLDYPSQCASLQREILEDAVTMLAEGGRLVY
                     STCTWAPEENEEIVNWLLEEYDFDLLPVEHINGMVAGIDLPETARMYPHQFKGEGQFV
                     AHLQFKGNNPAPKFKASKSNLSREQVALWQEFAQNHLKVNLPGILQIFGDQLYLLPEL
                     LPDLGKLKIARNGLHLGTFKKKRFEPSFALGLALKPSQVEQSVEIGQEEFVKYAAGET
                     VQLAESLPNGWYQVLVKGNGLGFAKVTGNVLKNYFPKGLRFK"
     gene            complement(48488..49261)
                     /locus_tag="VQU30_000122"
     CDS             complement(48488..49261)
                     /locus_tag="VQU30_000122"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="inositol monophosphatase family protein"
                     /protein_id="HET2446317.1"
                     /translation="MKSKFEFAKELVKKAGQYILDHMQEDLRVETKSSPTDLVTRLDK
                     EVQELLVGEILSRYPEDKICAEEGCLRASVQEGKVWVIDPIDGTNNFVAQQEDFAVMM
                     AYFENGQGQFGLIYDVVKGDCYHGGGEFPVCLNDRPLASFKTKPLGDFLIAGNSGMLE
                     TNEWGLADLSRAVLGVRVYGSAAISFAKILSGRLLTYLTYLQPWDYAAASILGESLGY
                     RVVTLFGEAPDFQTRQPVMMVPLEMQEEIQSYIYERKRT"
     gene            complement(49251..49529)
                     /locus_tag="VQU30_000123"
     CDS             complement(49251..49529)
                     /locus_tag="VQU30_000123"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002895777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UPF0223 family protein"
                     /protein_id="HET2446318.1"
                     /translation="MNKQYSYPLDLSWSTEELASVLSFFNDVEAAYEGKVEAKKLLDS
                     YKGFKAVVPSKSEEKRLGREFETVSGYSLYRAVQAAKEKGKGKISLEK"
     gene            complement(49529..49930)
                     /locus_tag="VQU30_000124"
     CDS             complement(49529..49930)
                     /locus_tag="VQU30_000124"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007556665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Spx/MgsR family RNA polymerase-binding
                     regulatory protein"
                     /protein_id="HET2446319.1"
                     /translation="MITLFLSPSCTSCRKAKTWLEKHKVPFVEHNIMTSPLTRKELQH
                     ILSLTENGTDDIISTRSKIFQKLNIDVESISVSELLHLIEQYPSLLRRPIIIDAKRMQ
                     IGFNEDEIRAFLPRSYRKQELKEARMRAGIS"
     gene            complement(50140..50757)
                     /locus_tag="VQU30_000125"
     CDS             complement(50140..50757)
                     /locus_tag="VQU30_000125"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000850480.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01906 family membrane protein"
                     /protein_id="HET2446320.1"
                     /translation="MKTKLTFWGSMLFLLSLSILLTIYLAWIFYPMEIQWLNLTNRVY
                     LKPETIQYNFHILMNYLTNPFSQVLQMPDFRSSAAGLHHFAVVKNLFHLVQLVALVTL
                     PSFYVFVNRIVKKDFLSLYRKSLLALVVLPVMIGLGGVLIGFDQFFTLFHQILFVGDD
                     TWLFDPAKDPVIMILPETFFLHAFLLFFALYESFFGYLCLKSRRK"
     gene            complement(50747..51520)
                     /locus_tag="VQU30_000126"
     CDS             complement(50747..51520)
                     /locus_tag="VQU30_000126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004258500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01457 family HAD-type hydrolase"
                     /protein_id="HET2446321.1"
                     /translation="MKYKGYLIDLDGTIYKGKDQIPAGETFVHELQKRDIPYLFVTNN
                     TTRTPESVKEMLAQNFNIDTPLSTVYTATLATIDYMNDLGLEKTVYVVGEAGLKEAIK
                     AAGYVEDKEKPAYVVVGLDWQVDYEKFATATLAIQKGAHFIGTNPDLNIPTERGLLPG
                     AGSLITLLEVATRVKPVYIGKPNAIIMDKAVEHLGLEREELIMVGDNYLTDIRAGIDN
                     GIPTLLVTTGFTKAEEVAGLPIAPTHVVSSLAEWDFDEN"
     gene            complement(51531..52268)
                     /locus_tag="VQU30_000127"
     CDS             complement(51531..52268)
                     /locus_tag="VQU30_000127"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000524807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl-[acyl-carrier-protein] thioesterase"
                     /protein_id="HET2446322.1"
                     /translation="MGLTYQMKMKIPFDMADMNGHIKLPDVILLSLQVSGMQSIELGV
                     SDKAILEDYNLVWIIVEYDIEVVRLPRFAEEITIETEALSYNRLFCYRRFTIYNEAGQ
                     ELIHMMATFVLMDRDSRKVHAVEPEIVAPYQSDFDKKLIRGPKYESLEESISKDYHVR
                     FYDLDMNGHVNNSKYLDWIFEVMGADFLTHYIPKKINLKYVKEVRPGGVITSAVERTG
                     LESKHEITSDGVINAQAIITWQEIKKA"
     gene            complement(52273..53403)
                     /locus_tag="VQU30_000128"
     CDS             complement(52273..53403)
                     /locus_tag="VQU30_000128"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oxygen-independent coproporphyrinogen III
                     oxidase"
                     /protein_id="HET2446323.1"
                     /translation="MQKKPTSAYVHIPFCTQICYYCDFSKVFIKNQPVDSYLEHLLEE
                     FRSYDIEKLSTLYIGGGTPTALSAPQLEVLLNGLTKNLDLSVLEELTIEANPGDLDAD
                     KIAVLKNSAVNRVSLGVQTFDDKMLKKIGRSHLEKDIYENIDRLKLAGFDNISIDLIY
                     ALPGQTMEQVKENVAKAIGLDIPHMSLYSLILENHTVFMNRMRRGKLPLPKEELEAEM
                     FEYIIAELERAGFEHYEISNFSKPGFESRHNLMYWDNAEYYGIGAGASGYVNGVRYKN
                     HGPIRHYLSAVEEGNACITEDHLSQKEQMEEEMFLGLRKKSGVSMARFEEKFGQSFAG
                     LYGEIVRDLVQQGLMQIEGDHVRMTKRGLFLGDTVAERFILE"
     gene            complement(53487..53876)
                     /locus_tag="VQU30_000129"
     CDS             complement(53487..53876)
                     /locus_tag="VQU30_000129"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000517372.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YtxH domain-containing protein"
                     /protein_id="HET2446324.1"
                     /translation="MGKLSSILLGTVSGAALALFLTSDKGKQVCSQAQDFLDDLREDP
                     EYAKEQVCEKLTEVKEQATDFVLKTKEQVESGEITVDSILAQAKSYAFQATEASKNQL
                     NNLKEQWQEKAEALDDSEEIVIDITEE"
     gene            complement(53892..54275)
                     /locus_tag="VQU30_000130"
     CDS             complement(53892..54275)
                     /locus_tag="VQU30_000130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000895045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF948 domain-containing protein"
                     /protein_id="HET2446325.1"
                     /translation="MLEVAYILVALALIVFLVYLIITVQKLGRVIDETEKTIKTLTSD
                     VDVTLHHTNELLAKVNVLADDINVKVATIDPLFSAVADLSLSVSDLNDHARVLSKKAS
                     SAGSKTLKTGASLSALRLASKFFKK"
     gene            complement(54276..55064)
                     /locus_tag="VQU30_000131"
     CDS             complement(54276..55064)
                     /locus_tag="VQU30_000131"
                     /EC_number="2.4.99.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000886660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prolipoprotein diacylglyceryl transferase"
                     /protein_id="HET2446326.1"
                     /translation="MLDPIAIQLGPLAIRWYALCIVTGLILAVYLTMKEAPRKKIIPD
                     DILDFILVAFPLAILGARLYYVIFRFDYYSQNLGEIFAIWNGGLAIYGGLITGALVLY
                     IFADRKLINTWDFLDIAAPSVMIAQSLGRWGNFFNQEAYGATVDNLDYLPGFIRDQMY
                     IEGSYRQPTFLYESLWNLLGFALILIFRRKWKSLRRGHITAFYLIWYGFGRMVIEGMR
                     TDSLMFFGLRVSQWLSVVLIGLGIMIVIYQNRKKAPYYITEEEN"
     gene            complement(55057..55992)
                     /locus_tag="VQU30_000132"
     CDS             complement(55057..55992)
                     /locus_tag="VQU30_000132"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HPr kinase/phosphorylase"
                     /protein_id="HET2446327.1"
                     /translation="MSVLVKEVIEKLRLDIVYGEPELLEKEINTADITRPGLEMTGYF
                     DYYTPERIQLLGMKEWSYLISMPSNSRYEVLKKMFLSETPAVIVARGLVVPEEMLKAA
                     RECKIAILTSRAATSRLSGELSSYLDSRLAERTSVHGVLMDIYGMGVLIQGDSGIGKS
                     ETGLELVKRGHRLVADDRVDIFAKDEITLWGEPAEILKHLIEIRGVGIIDVMSLYGAS
                     AVKDSSQVQLAVYLENYDTHKTFDRLGNNAEELEVSGVAIPRIRIPVKTGRNISVVIE
                     AAAMNYRAKEMGFDATRLFDERLTSLIARNEVQNA"
     gene            complement(56122..56298)
                     /locus_tag="VQU30_000133"
     CDS             complement(56122..56298)
                     /locus_tag="VQU30_000133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000048061.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S21"
                     /protein_id="HET2446328.1"
                     /translation="MSKTVVRKNESLDDALRRFKRAVTKAGTLQETRKREFYEKPSVK
                     RKRKSEVARKRKKF"
     gene            complement(56438..57145)
                     /locus_tag="VQU30_000134"
     CDS             complement(56438..57145)
                     /locus_tag="VQU30_000134"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269928.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucosamine-6-phosphate deaminase"
                     /protein_id="HET2446329.1"
                     /translation="MKVIKVENQVQGGKVAFEILKEKLANGAQTLGLATGSSPLEFYK
                     EIVESDLDFSNLTSVNLDEYVGLDGDNPQSYRYFMQENLFNQKPFKESFLPRGVKDNA
                     EAEVERYNQILADHPVDLQILGIGRNGHIGFNEPGTPFDSQTHLVELDQSTIEANARF
                     FAKIEDVPTQAISMGIKNILDAKSIILFAYGESKAEAIAGTVSGPVTENLPASSLQNH
                     PDVTIIADAEALSLLEK"
     gene            57296..58324
                     /gene="queA"
                     /locus_tag="VQU30_000135"
     CDS             57296..58324
                     /gene="queA"
                     /locus_tag="VQU30_000135"
                     /EC_number="2.4.99.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014931869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA preQ1(34) S-adenosylmethionine
                     ribosyltransferase-isomerase QueA"
                     /protein_id="HET2446330.1"
                     /translation="MNTADFDFHLPEELIAQTPLEKRDASKLLIVNRETGEMQDKHFH
                     SIINMLEPGDALVMNDTRVLPARLYGQKVETGGHVELLLLKNTSGDEWEVLAKPAKRL
                     KVGTRISFGDGRLSAVVTEELTHGGRIVRFEYQGIFLEVLESLGEMPLPPYIHEKLDD
                     RERYQTVYAKESGSAAAPTAGLHFTKELLAEIQAKGVHLVYLTLHVGLGTFRPVSVDN
                     LDEHEMHSEFYQLSEEAAATLRSVKENGGRVIAVGTTSIRTLETIGSKFDGQIQADSG
                     WTNIFIKPGYEWKVVDAFSTNFHLPKSTLVMLVSAFAGRELVLDAYHHAIQEHYRFFS
                     FGDSMFIY"
     gene            complement(58995..59384)
                     /locus_tag="VQU30_000136"
     CDS             complement(58995..59384)
                     /locus_tag="VQU30_000136"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000240828.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase family
                     protein"
                     /protein_id="HET2446331.1"
                     /translation="MVKRRIRRGTREPEKVVVPEQSSIPSYPVSVTSNQGTDVAVEPA
                     KAVAPTTDWKQENGMWYFYNTDGSMATGWVQVNGSWYYLNSNGSMKVNQWFQVGGKWY
                     YVNASGELAVNTSIDGYRVNDNGEWVR"
     gene            complement(59438..60145)
                     /locus_tag="VQU30_000137"
     CDS             complement(59438..60145)
                     /locus_tag="VQU30_000137"
                     /inference="COORDINATES: protein motif:HMM:NF019142.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="G5 domain-containing protein"
                     /protein_id="HET2446332.1"
                     /translation="MFRRNLNTSFVHAADGIQYVRDDTRDKEEGIEYDDADNGGIIVK
                     VATKPKVVTKKISSTRIRYEKDETKDRSENPVTIDGEDGYVTTTRTYDVNPETGHVTE
                     QVTVDRKQATDTVIKVPAKSKVEEVLVPCATKYEADNDLSAGQEQEITLGKNGKTVTT
                     ITYDVDGKSGQVTESTLSQKEDSQTRVVKKGTKPQVLVQEIPIETEYLDDPTLDKSQE
                     VEEVGEIGKLLLLQSIL"
     gene            complement(60845..61396)
                     /locus_tag="VQU30_000138"
     CDS             complement(60845..61396)
                     /locus_tag="VQU30_000138"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000835652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HET2446333.1"
                     /translation="MKSIGTQILQTERLILRRFVESDAEAMFQNWASSAENLTYVTWD
                     PHPDIEITRNSIRNWVASYTNLNYYKWAICLKENPEQVIGDISIVKIDEADLSCEIGY
                     VLGKAYWGNGMMTETLKAILDFCFTQAGFQKVRARYASLNPASGRVMEKAGMSYLQTI
                     VNGVERKGYLADLIYYGISREEC"
     gene            complement(61794..62618)
                     /gene="nadE"
                     /locus_tag="VQU30_000139"
     CDS             complement(61794..62618)
                     /gene="nadE"
                     /locus_tag="VQU30_000139"
                     /EC_number="6.3.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000058066.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ammonia-dependent NAD(+) synthetase"
                     /protein_id="HET2446334.1"
                     /translation="MSLQETIIQELGVKPVIDAQEEIRRSIDFLKRYLKKHPFLKTFV
                     LGISGGQDSTLAGRLAQLAMEELRAETGDDSYKFIAVRLPYGVQADEADAQKALAFIQ
                     PDVSLVVNIKESADAMTAAVEATGSPVSDFNKGNIKARCRMIAQYALAGSHSGAVIGT
                     DHAAENITGFFTKFGDGGADILPLYRLNKRQGKQLLQKLGAEPALYEKIPTADLEEDK
                     PGLADEVALGVTYAEIDDYLEGKTISPEAQATIENWWHKGQHKRHLPITVFDDFWE"
     gene            complement(62615..64075)
                     /locus_tag="VQU30_000140"
     CDS             complement(62615..64075)
                     /locus_tag="VQU30_000140"
                     /EC_number="6.3.4.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinate phosphoribosyltransferase"
                     /protein_id="HET2446335.1"
                     /translation="MYPDDSLTLHTDLYQINMMQVYFDQGIHNKKAVFEVYFRQQPFK
                     NGYAVFAGLERIVNYLEDLRFSDSDIAYLESLGYHGAFLDYLRNFKLELTVRSAQEGD
                     LVFANEPIVQVEGPLAQCQLVETALLNIVNYQTLVATKAARIRSVIEDEPLMEFGTRR
                     AQEMDAAIWGTRAAVIGGANGTSNVRAGKLFDIPVLGTHAHALVQVYGNDYEAFKAYA
                     ATHKNCVFLVDTYDTLRIGVPAAIQVARELGDQINFMGVRIDSGDIAYISKKVRQQLD
                     EAGFTEAKIYASNDLDENTILNLKMQKAKIDVWGVGTKLITAYDQPALGAVYKIVAIE
                     DETGQMRNTIKLSNNAEKVSTPGKKQVWRITSREKGKSEGDYITYDGVDISDMTEIKM
                     FHPTYTYIKKTVRNFDAVPLLVDIFKEGILVYNLPSLTDIQDYARKEFDKLWDEYKRV
                     LNPQHYPVDLARDVWQDKMDLIDKMRKEALGEGEEE"
     gene            complement(64191..64679)
                     /locus_tag="VQU30_000141"
     CDS             complement(64191..64679)
                     /locus_tag="VQU30_000141"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000797183.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2446336.1"
                     /translation="MKNRFYYYQLLDEREEQLINKAGSESFYICIALSLLSYIISVLA
                     PSLFNSNMLLIVIIIGTFYFFNRARYLGVTYYSRFHFTILGCFFLTLAITALLMLQNY
                     QFNIEIYQHNPLNFKYLSAWVITYVIYLPWVFIGNLGLKSYGEWAQKKFEQDMDELES
                     GE"
     gene            complement(64669..64878)
                     /locus_tag="VQU30_000142"
     CDS             complement(64669..64878)
                     /locus_tag="VQU30_000142"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013670190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HET2446337.1"
                     /translation="MAKNLKLKLARVERDLTQGQLAEAVGVTRQTIGLIEAGKYNPSL
                     SLCQSICRCLGKTLDQLFWEEEDEK"
     gene            complement(65268..65710)
                     /locus_tag="VQU30_000143"
                     /pseudo
     CDS             complement(65268..65710)
                     /locus_tag="VQU30_000143"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000640911.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(66002..66808)
                     /locus_tag="VQU30_000144"
     CDS             complement(66002..66808)
                     /locus_tag="VQU30_000144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET2446338.1"
                     /translation="MILKDINFALNKGEIVGLVGRNGVGKSTLMKILVQNNQPTSGNI
                     ISSDNVGYLIEEPKLFLSKTGLENLKYLSNLYGVDYNQERFRSLIQELDLTQSINKKV
                     KTYSLGTKQKLALLLTLVTEPDILILDEPTNGLDIESSQIVLAVLKKLALNENVGILI
                     SSHKLEDIEEICERVLFLENGLLTFQKVGKDSHNFLFEIAFSSATDRDIFITKQEFGD
                     IVQEEGLRITMSGNIQSSELFKFFNENSIKVVDFETKKETLKDIYLNRSK"
     gene            complement(67214..67942)
                     /locus_tag="VQU30_000145"
                     /pseudo
     CDS             complement(67214..67942)
                     /locus_tag="VQU30_000145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000169115.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="U32 family peptidase"
     gene            complement(68178..68489)
                     /locus_tag="VQU30_000146"
     CDS             complement(68178..68489)
                     /locus_tag="VQU30_000146"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398245.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2446339.1"
                     /translation="MIEAQGFLVDKQTRCIHYHSKLDIIALQCYVCKKYYACYRCHDS
                     LENHPFEPYPLSLIQDKPILCGVCLKLLTYKQYKESLSCPFCFSRFNPGCQNHKERYF
                     K"
     gene            complement(68504..69790)
                     /locus_tag="VQU30_000147"
     CDS             complement(68504..69790)
                     /locus_tag="VQU30_000147"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000169115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="U32 family peptidase"
                     /protein_id="HET2446340.1"
                     /translation="MTKTLKRPEVLSPAGTLEKLKVAVQYGADAVFIGGQAYGLRSRA
                     GNFTFEQMEEGVQFAAKYGAKVYVAANMVMHEGNEAGAGEWFRKLRDIGIAAVIVSDP
                     ALIMIAATEAPGLEIHLSTQASATNYETLEFWKELGLTRVVLAREVSMKELAEIRKRT
                     DVEIEAFVHGAMCISYSGRCTLSNHMSMRDANRGGCSQSCRWKYDLYDMPFGKERKSL
                     KGEILEEFSMSAVDMSMIDHIPDMIENGVDSLKIEGRMKSIHYVSTVTNCYKAAVDAY
                     LESSEKFEAIKQNLVDEMWKVAQRELATGFYYGTPSENEQLFGARRKIPEYKFVAEVV
                     SYDDATQTATIRQRNVINEGDQVEFYGPGFRHFETYIEDLHDAKGNKIDRAPNPMELL
                     TIKVPQPVQAGDMVRALKEGLINLYKEDGTSVTVRA"
     gene            70414..70596
                     /locus_tag="VQU30_000148"
     CDS             70414..70596
                     /locus_tag="VQU30_000148"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001262531.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ApaLI family restriction endonuclease"
                     /protein_id="HET2446341.1"
                     /translation="MANDNKSHYLIYRVLGISFEEGENIDLYQNKGRFLYKYAGSFLE
                     EAAVLSFNEKFGTENT"
     gene            70606..70971
                     /locus_tag="VQU30_000149"
     CDS             70606..70971
                     /locus_tag="VQU30_000149"
                     /inference="COORDINATES: protein motif:HMM:NF021048.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ApaLI family restriction endonuclease"
                     /protein_id="HET2446342.1"
                     /translation="MPNSENTKPKTFEIDCLVGEKHAYEIKWWDATTDGDHITKEHTR
                     IKVIHNKGYIPIRLMFYYPNRTQAIKIQQTLETLYNGIGGKYYYGDSAWEHLRAVTGI
                     DLLSILTDIANKKTGVKSK"
     gene            70968..72158
                     /locus_tag="VQU30_000150"
     CDS             70968..72158
                     /locus_tag="VQU30_000150"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific DNA-methyltransferase"
                     /protein_id="HET2446343.1"
                     /translation="MTVLKGDNLEILKTIESSSIDLIYMDPPFFTQKTQKLSNNKNIM
                     YSFEDTWTSIEDYKEFLSVRLEECKRVLKNSGSIFVHCDKIANHHIRLILDNIFGADM
                     FQSEIIWNYKRWSNSKKGLLNNHQNIYFYSKSKDFKFNTIFTEYSSTTNIDQILVERK
                     RNGNSKTIYKVDNNGNYILAKEKNGVPLSDVWNIPFLNPKAKERVGYPTQKPILLLEQ
                     IIKIATDKNDIVLDPFCGSGTTLVASKILNRNYMGIDLSEEAINITQQRLENVIKTSS
                     NLLNKGIEAYRTKTEEEENILKLLQAKIVQRNKGIDGFLPKHFQKKPIPIKIQKNNEC
                     LNESISLLQNAINSKKLDFGVVIKTHSDNLLFDFDTIPENIIVVDHFELTIEKWLSKS
                     QQLL"
     gene            complement(72673..73665)
                     /locus_tag="VQU30_000151"
     CDS             complement(72673..73665)
                     /locus_tag="VQU30_000151"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000122906.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HET2446344.1"
                     /translation="MSYYDFVKDYMKVDECKNNEKYSSAGHTFCWKKENSTYAEGLYW
                     FYEGGSFIIDIHDFYIKEEVVQNSTYSMSDYVSIYSSYIVSANGEKFNPYQTITANSL
                     CTFDFDNIKDDFVFLLHENCCYLAVSIGFKKELIEKHLASININPESFYSTLLQPNQI
                     ILTKALERVAMEILNCKMDAPAADFFFKAKANEWISIVIDTYLNRKKYKIEIDDDKAL
                     EDVARFLDDHFATNVNQGTLEKISKMSGTKLKNLFKEKYCQSITEYTQRKRMNVAETL
                     LLNTELPIKEIAESVGYSSASKFSIYYKRYKGKLPSEVRNLACKHHNFKCDYCD"
     gene            73825..75579
                     /locus_tag="VQU30_000152"
     CDS             73825..75579
                     /locus_tag="VQU30_000152"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398247.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET2446345.1"
                     /translation="MKIYKKLFAYVQDKKYLGVLAIIFSAISAVLTVYGYYLIYKFLD
                     KLIINSNLSGAESIALKSVITLTSGAIFYFVSGMFSHILGFRLETNLRKRGIDGLEKA
                     SFRFFDLNPSGQIRKIIDDNAAQTHQVVAHMIPDSSQAIVTPILVLVLGFIVSIRVGI
                     ILLALTIIGGLILGAMMGEQEFMKIYQESLSKLSAETVEYVRGMQVVKIFKANVESFK
                     SFYKAIKDYSKYAYDYSLSCKRPYVLYQWLFFGLIAILIIPIVYFMTSLASAEVILLE
                     LIMILFLSGVLFVSFMRMMWYSMYISQGNYAVDTLEALYEDMQKDKLVHGNVNNFKNY
                     NIEFENVSFAYNDKAIIENLSFNLEEGKSYALVGSSGSGKSTVAKLISGFYNVNKGSI
                     KIGGIAISEYSDEALIKAISFVFQDSKLFKKSIYDNVALANKDATKDDVMRALKLAGC
                     DLILDKFPERENTIIGSKGVYLSGGEKQRIAIARAILKDSKIIIMDEASASIDPDNEF
                     ELQKAFKNLMKDKTVIMIAHRLSTIKDLDEIIVMDSGKIIERGSDKELMSKDTRYKSL
                     QEMFNSANEWRVSNERVL"
     gene            75563..77284
                     /locus_tag="VQU30_000153"
     CDS             75563..77284
                     /locus_tag="VQU30_000153"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019214631.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET2446346.1"
                     /translation="MKEFYKKRFALTDGGARNLSKATLASFFVYCINMLPAILLMIFA
                     QEVLENMGKSNGFYIVFSVLTLIAMYILLSIEYDKLYNTTYQESADLRIRTAENLSKL
                     PLSYFSKHDISDISQTIMADIEGIEHAMSHSIPKVGGMVLFFPLISVMMLAGNVKMGL
                     AVIIPSILSFIFIPLSKKYQVNGQNRYYDVLRKNSESFQENIEMQMEIKAYNLSKDIK
                     DDLYKKMEDSERIHLKAEVTTILTLSISSIFSFISLAVVIFVGVNLIINKEINSLYLI
                     GYLLAAMKIKDSLDASKEGLMEIFYLSPKIERLKEIQNQDLQEGDDYSLKKFDIDLKD
                     VEFAYNKDAKVLNGVSFKAKQGEVTALVGASGCGKTTILKLISRLYDYDKGQILIDGK
                     DIKEISTESLFDKVSIVFQDVVLFNQSVMENIRIGKQDASDEEVKRAAKLANCTDFIE
                     KMDKGFDTVIGENGAELSGGERQRLSIARAFLKDAPILILDEITASLDVNNEKKIQES
                     LNNLVKDKTVVIISHRMKSIENADKIVVLQNGRVESEGKHEELLQKSKIYKNLIEKTK
                     MAEEFIY"
     gene            77295..77924
                     /locus_tag="VQU30_000154"
     CDS             77295..77924
                     /locus_tag="VQU30_000154"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000368976.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MptD family putative ECF transporter S
                     component"
                     /protein_id="HET2446347.1"
                     /translation="MDNKKLKVKDLVSIGVFGVIYFAFMFGVGMMGLIPILFLIYPTV
                     LAIVAGTVVMLFMAKVQKPWALFIFGMISPLVMFAAGHTYVVVVLSLIVMIIAELIRK
                     IGNYNSFKYNMLSYAIFSTWICSSLMQMLLAKEKYMEWSLMTMGKDYVDVLEKLITYP
                     HMALIALGAFLGGILGAYIGKALLKKHFSNGLYCVGYFTPCLILWCYLN"
     gene            77825..78382
                     /locus_tag="VQU30_000155"
     CDS             77825..78382
                     /locus_tag="VQU30_000155"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001851583.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter transmembrane
                     protein EcfT"
                     /protein_id="HET2446348.1"
                     /translation="MYRQGSIEKTLFKWIILCGILYSLPNFMVLSELNPIVKMFLSIP
                     IVIRMFILPFMAASFMIKTSDVGAIISSMDKLKISKNVSIPIAVMFRFFPSFKEEKKN
                     IKMAMRVRGINFKNPVKYLEYVSVPLLIISSNISDDIAKAAETKAIENPIAKTRYIRV
                     KIQLIDFVYVLAVAGLIVGGLIWLK"
     gene            78370..79734
                     /locus_tag="VQU30_000156"
     CDS             78370..79734
                     /locus_tag="VQU30_000156"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002837029.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET2446349.1"
                     /translation="MVEIKNLSLDYGEEHILDDISLSIAEGECVLFTGKSGSGKSSLI
                     NSINGLAVRYDNAKTKGEIIIDGKNIKNLELYQISMLVSTVFQNPKTYFFNVNTTLEL
                     LFYLENIGLAREEMDRRLKDILEIFPIKNLLNRNIFNLSGGEKQILCIAASYIAGTKI
                     IVMDESSSNLDIKSISVLAKMLKILKEKGISIIVAEHRIYYLMDIVDRVFLIDKGKLK
                     KTYTRSEFLKLDKNELNALSLRDKELSKLKVPYLKEGGEYQIKNLSYKFTDDECLSLK
                     DISFKLGKIYGIIGSNGRGKSTLLRCLIGLEKKSKEEIYFKGEKLSKKERLKNSSLVM
                     QDVNHQLFTDEVFNELRLGVKNFDEEKAKIILKDLGLDEFIERHPMSLSGGQKQRLAI
                     ASVMCKTSPFIFFDEPSSGIDYSNMIKISELINKYKTMDKIIFIVSHDIEFLNEVADE
                     IFEL"
BASE COUNT        24744 a        17125 c        14753 g        23830 t
ORIGIN      
        1 acctacggct agcttcctag tttgctcttt gattttcatt gagtattaca gtaaacaatt
       61 tttctagcta ttgtaacaaa aaagtcactc gaaggcaact tttttcgtcc ataaactttc
      121 aaaagagaat ggcttattca gaactaaaag ccgcagcttt ttgcatttgg taatacttac
      181 cctttctatc catgagttct tgatggttac catattcaac aatatcacca tctactaaga
      241 caagaattaa atccgcatcc tgaatggttg acaaacggtg agcaatgatg aagcttgtgc
      301 ggcccttcat gagttttgca aaggcatcct gtaccagcac ttctgtccgt gtatcaatgg
      361 aagaagttgc ctcgtctaag ataagaatct ttggaatagc cagaaagact cgggatatgg
      421 tcaagagctg agcttggccg acagagagag attctccagc attttccaac ttggtatcgt
      481 atccctgtgg caactgttgg atgaaaaagt ctgcattagc tgctttggca gcagcaatta
      541 cttgctctcg actggcttca ggattgccaa aggcaatatt atcatgaatg gtcccttgtg
      601 tgagccaggt ttcttgaagc accataccaa actgctgtct caatgatact cgtgtataat
      661 cataaatgga ttgcccatcc agcaagatat ctcccgagct aatgggataa aaacgcataa
      721 ggagattgat aagagttgat tttccagcac ctgtcggacc aacgatggct accttactac
      781 cagctggaat atcgatagac aactccttaa tcaaaatttt ttcaggatgg tagccaaaag
      841 agacatgttt aaaggaaata gctcccttaa cttggtcact ggtcaagact tccttacctg
      901 tttcagccac ttcagggcta tctaagaccc catagatacg ctctacgcaa gccagagcac
      961 tttgcaactc agctagcact gaagaaatat cgttaaaggg cttggtgtat tgctgaacat
     1021 agttcaaaaa agtcactaaa cgaccgacgg tcaaggttga acccatcatg atacgataag
     1081 ctcctactcc agctaaaagg gcataaatga gtgcatttac aaagcgagtc gaaggattga
     1141 ccgttgaaga ataaaagatg gctgactgag aatagcctga gtagttgtca tgagcctcac
     1201 gcaatctttg gataaattct gtttgagcat tgaaggactg gattatagtc tgctggctaa
     1261 gcgattcttc aatcaactga gtctgaattc ccctcgtctc tgtttgcttc tggaagagat
     1321 gataggatct cttggcaata aagcgtgaaa tcaccatgga cagtggcgtc aacagcaaga
     1381 ctaagagagt catgaggaga tgaatttgga gcatggctag aatactaacc aaaatcatca
     1441 aaacaccaat gaaaaattgg ttaaaaatca tggtcaagcc agctgccaac tgttcgatat
     1501 ccgtggttac acgactgacc atctctccat tgccttgccg atccgcaaaa gcaatcggta
     1561 accgatggag tttatggatg attcgctctc gtaaatctct ggtataagag aagattagac
     1621 gattatagag gagaggattg gcccattgta ccagagtatt tcctattacc accaagagca
     1681 tctggagaaa aatctgccaa aaaactggtg atgaaccagc cactaggact tggtcaatga
     1741 cctgcccaat cagaataggt aggtaaattg ataagccaac ttgggcaata gttcctagaa
     1801 aggctaggaa aaggaggaag ggatggtttg ctaaatctac gactaaacgt ttgagcgtct
     1861 ggtttacagt ttgtcgtttc attctagtcc tcctttccat gttgggatgc attgatttca
     1921 cgatagactt gactggattt catcaagtca tcgtgcttgc caacagctag caactcacct
     1981 ttttccaaga ggagaatctg gtccgccatc tggagtgtcg aagtccgttg agaaatcaag
     2041 attaagctca tatttggcag attttcgcgg atagctttca agagcttgga ctctgtaatg
     2101 gtgtccagtg ctgaggtcgc atcatctagg atgagaaacg gagcctggcg caagactgct
     2161 cgtgcgatag acagcctttg tttttgtcca cctgagaaat ttcgccctcc tgcttcaact
     2221 agagcatcca agagtccttc cttatcactg acaaaatcct tagcttgcgc aatctccaag
     2281 gcttgccaga gttcttgatc agtcacttct tgatttaaac ctaaagtcaa gttggaacga
     2341 atagttccct taaagagttc gaccttttga ggtacatagg caatccaaga ccgccactgc
     2401 tccaaattaa gaggactacg tccattttga taaaggtcaa tgttcccctt gtctactgga
     2461 taaagtccaa gtaagagttg caccaagctt gatttaccag aaccagtccc cccaatgata
     2521 ccaaggattt gtccttgagt catatcaaag gaaatgtctc tcagagaagg ctgggccgca
     2581 tcaggatagg taaaagtcaa ttcttggact tgtaaaaccc gaccactggt aacttgcttt
     2641 tgttctaatt ctgaatggat gttttcggga gattccgcaa agacctcctc gattctcttg
     2701 gctgagatat aggactggtt gagggaattg atcagcatgg ctagcttgac caattccacc
     2761 aaaatctgta agaggtaatt gataagagca atgagagcac cttgactgag tactcctcct
     2821 tgaattgaaa tatagccttg ccagataata acgagaagag ttccattgac aatcagatag
     2881 gtcagaggtg ttaataaact agacaagaaa cctgtctttt cttgtaatct agcataaact
     2941 tggttaaggg tttgaaaaat ctgtaactct cgtttttctt gaccaaaagc acgaataacc
     3001 cgcatccctt gcaattgctg gcgcgtttcc tgaaccagtt ggtccgtttt ctttctgaga
     3061 ctactgtaga gaggattgac caatcgagat aaccctacaa tgacaatggt caaaatggca
     3121 accatgacta agaaccagaa agtcaactca gctgagattc gataagccat aaaaatggca
     3181 ccaaaaacga taatgggcgc tcgtaaaaag agacgcagga attgattgat accagtctga
     3241 atctggtagg tatccgaagt caagcgagta accaaactag aagttgtcag acggtctctg
     3301 ctgtcctttg gcaaggaaag aatatgacga taaagatcgt ttgtcaattc cttagcaaaa
     3361 cctactgctg cctttgctga gtaaaattga gctatcaagg ccactaaaac gccaattact
     3421 gcaaagataa ggagcaggcc aatctgcatc cagagatgac cttgatctcc ctgaggtaaa
     3481 gattggtcaa caatcccagc aatcaccatg ggaaccaaga gctcaaaaac agcttctaac
     3541 agcttgaaca agggggctaa aattgattcc ttgatgtagg gtttgaagta agataatagg
     3601 tgtttcataa atcccttcta ttcatattct agaaatgaag aaagtgggaa gccccactct
     3661 ctgttttatt tgtttaagta aggcaataga tagccatatc ctgctttttc catctcatcc
     3721 ttggccacaa agcgtaaaga agcagaattg atacagtaac ggaggccgcc taactcccgc
     3781 ggtccatctg tgaaaacatg acccaagtga gcactgcctg aacgagaacg aacttcaatt
     3841 cgctccattc catggctcag atccttgtaa taatgaatca actctttgga aatcggacgg
     3901 ctaaaacttg gccaaccaca acctgaagca aacttatcct tggcaaaaaa gagtggctca
     3961 cctgtcgtaa tatctacata aatcccctct tcaaaggttt ggtcataggc attggtaaat
     4021 ggagcctctg tagcagcttc ttgtgtgaca cgataagact cttcagatag actggccttc
     4081 aacacctctt gactaggctt ttcatagttt gctgcatcaa tcaatggctt atcagcatcg
     4141 gtcacatcga tatgacagta acctgaagga ttcttcctga gatagtcttg gtggtagtct
     4201 tcagccagaa tgtagtggcg taattgctcc acttctactg caatctttcg acccagcatg
     4261 cgttcctgct cctgcaccac tgtgtagata gctggcaaat ctgcttcatc ctgataataa
     4321 atcccagttc gatattggcg accacggtca ttcccttgtt gattgataga tagaggatcg
     4381 ataactcgga aataataaag taaaatctct ctgagtgaca cttccttctc atcgtaaatc
     4441 acttggaccg tttctgcatg gtctgtttcc ttgatcaact ggtaattggt cgtttcgact
     4501 tgaccattag cgtagccaac actggtttct agcactccag aaatgcgtga aaaatattcc
     4561 tctaggcccc aaaaacaacc acctgctaga taaatttctg ccatctttat ttctccttta
     4621 tcacgttttt aactaatact cttcgaaaat ctcttcaaac cacgtcagcg tcaccttacc
     4681 gtaggtatgt tactgacttc gtcagttcta tctgcaacct caaaacagtg tcttgagctg
     4741 acttcgtcag ttctatctgc aacctcaaaa cagtgttttg agcagcctgc ggctagcttc
     4801 ctagtttgct ctttgatttt cattgagtat aaacttcttt tcacaaaaag gatatgaaac
     4861 cctctggtca agagtttccc catcctatct tctattcttt attttgcttc tacacggaca
     4921 cctttggtat caactctcaa gtcatgcagt tttcctttga aaggttgctt ttccaattct
     4981 gccttaattg ttggcatctt gtcatgagaa gccagaacca taactgtcgg cccagcacca
     5041 gaaaggtagg ttgcataggc cccattttct ttggtcactt gcttaatcat cgcaaattct
     5101 cttaccaagt cctgacgata gcgctcatgg aagaggtctc cctcgattgc ttgcccagcg
     5161 gtcaccatgt ctcctgccaa caaggcagca accgctacat tggcgataga acttgcagca
     5221 acagcttcct tataagacaa ttttttaggc aagacactac ggctgtcgcg agtacgtaat
     5281 tcatagtttg gaatgtaagc tagaaaatca cactctggaa agtctgctac gatagcagag
     5341 acttgccctt caacagaact tgcaataacg agattaccat aaatggctgg agccacattg
     5401 tcaggatgcc cttcaatctt ggtcgctaac tgcaattttt catggtctga taagttgagt
     5461 tgacccagtt ggttggctag ttcaatccca gcaacgataa ccgagctgga agaacccaaa
     5521 ccgcgcgcca aagggacatc actggtcatt ttcaagcgtc ttggttgcaa gtctggtaca
     5581 atttgcaaag cgattttaag caagagatta cgctcgtcat gtggaatcca tttgccaatc
     5641 tggtgttcaa tcagccactc atctcgttct tcgcagacct caatttgaag atacttggtt
     5701 acagctacac cgaccgagtc aaaacctggc ccgatattgg cactggttgc aggtacaata
     5761 atcttcatct tattctccta gcaccttgaa ggtattcaag aggtcgaatt ctgaaacctt
     5821 cttcaattca gctgagacat tttcaagctg ggctttatta atcttgtgtg tgatgataac
     5881 gacacgcgcc ttgtcaccct ctttgccatc ttgaaggatt tgcttaaagg aaatatcttg
     5941 agcattgaag atttcagcca acttcaagac ctgacctttt gagtctagag ccaagattga
     6001 gaaatagtag tttgctttga catcttcagg atttgccaag accaagtcac ggctatattc
     6061 gttgaagtct ttgccaatag taccatcatt caaacgacga acgatacgga caatatcagc
     6121 tacaacactt gttgcagttg gtttttgacc cgcacctggt ccgtagtaca tagactcacc
     6181 aataccgata gattctacaa agacagcgtt cattacgcca ttcacactag caagtgggtg
     6241 cgctttaggt aggaaggttg gagtcacttc tgcagcaata cctgaagaag tttcctcaat
     6301 agaaccaacc aatttcacta cgtaaccaag ctcttgagct acagctacgt cttctggtgt
     6361 gatattgcgg attcccttgt gggctacatc atcaaaggca atcttcatgc caaaggcaaa
     6421 ttggctcaaa ataaccatct tgtaggctgc atcaatccca tctacgtcat tcgtcggatc
     6481 gctttctgca aatcctagac gttgtgcttc cgcaagagca tcatcgtaag accagccttc
     6541 ttccaccatc ttggtcacca tgaagttgga agttccgttg actactccaa gcacgcgcgt
     6601 aattttatca gaagccaagg aatttgctaa agtacgaaga attggaatcc caccagcaac
     6661 tgctgcttcg tagtaaagtg ctaccttgtt agcttgagcg atttctagca attctgcgcc
     6721 atggacagct aaaaggtcct tgttagcagt aacaacgtgt tttccagctt ccaaggcacg
     6781 agtgataaag gttttagcag gctcaatacg ccccatcaat tccactacga tagtaatatc
     6841 ctggtctgat aaaatatcat ccacattggt tacaaagtta aagtcattcc ctgctgcaag
     6901 caagcgattt ttttcatctt catccttgac caatacctta gcaactttga tatctgaatg
     6961 tgctgattga ttgatttttc ctccattttc ctttaggagg aaaggcacac cacttgcaac
     7021 ggtaccaaat cctagtaaag caattttaac tgtcatcttt atctcctcga aattttctaa
     7081 tatagccatt ataacagaat tttgtgaaaa ttcctattat agtaaatcac tatttcagta
     7141 taaaaagaaa aaacgaatca gacgattcgc tcttcttaaa atctgaaaat agctttccag
     7201 aaaagattag ccgatttttt gcagattgag cactgcatcg tgactcatca agacttgacc
     7261 atactcttgt aagactgagc gactgatatc actatcgtct gcaaactcgc gcatacgggc
     7321 caacagccaa gctggatatg ggcttggatg attttcaata tccactaaaa tggtcaaata
     7381 atagcgctcg ttcattttgt agagttcaga agtttccatt tcaaaagtca ctgtcttggc
     7441 aaaagctacc aagtcagcca acttagcaaa agaaaggatg tagtagatgt aaggttcttt
     7501 cttactctca gcttcttgtt cagcctgctc ttgctcttct tccttggctt caacttgctc
     7561 aagagattga atggcttcga tatcatcctt ggttttgtct gcgatgcttt tttccagggt
     7621 tttgataaat tcatctggag acatttgagc caattcttcc atatctggca aatccgataa
     7681 gtcttcaaaa tctagatttt ggtcaatctt tgacttggtc acaaagacat ctaccttatc
     7741 aggttttgga gtcacacgga agctcaacat gcctgtatcc agaaagctat caggcatctc
     7801 tagctcatcc aagatagcat aaaagaactc ttctgttttt tcttgaggaa cgagaaagtc
     7861 agcaatctcc attccacgat ccatcaaatc ctctaaagac atcgtgattt ttaaagttgt
     7921 atcactaatt tgtttcattt tcattgctag taacctcata ctttcagttc tatctattat
     7981 actagatttt tacgatttta tcaaaagaag gctcctctat acggatagat tttccctagg
     8041 gtctttctat aggagactcc aagagaaaat ttctgcagac agatagaaaa agccttcaaa
     8101 atcggctaag agccgatttt gaagacctta tacatcagaa tacttataat ttaaaggttg
     8161 ctacaccgag gatagaacga tttaagtttc tgagaatttg aagactttgc tcaaatttct
     8221 tataacgagt cactccgtac tcttcaacaa gaaggactgt atctctttcc aaaagagatg
     8281 atacatcctg taaatctaca aaatgcattc cttttaaagc ttcttgactc tgtttcaatt
     8341 tatctaggat agctttattt gagctaacga tggtcaattc ctgtccagta tttttgtatg
     8401 acaaaacatc tgctaggtta gcaattgttg taatctctgt tacaaaatca atttgatact
     8461 gagaaaaatc acctactcta ttgattgttg gattaaagag ataaactaac acatttccca
     8521 tcacaaccaa aatcacacaa accactccaa taacaactaa acgaagaatc agatttttca
     8581 catttaagcc aagcgctgtt tcaccatttg cgttcaattc tttagagttg atggtttcca
     8641 gtttttcaat tttcacattt gcataggcat gtttaaattt ctcaatcaac ccatcaattt
     8701 ttttctctaa caagtcattg gcatctttac ttgatgtcaa aattttcaca ccaacccctg
     8761 catcgtcaat catatagtag acggtcaatt ttttccacca atagtcattc gttgaatttt
     8821 tcaaggttgt ttctgtcgtg tctaattcac tggcaatttt tttcaactca ctgggttcta
     8881 catcattgaa aagataagct ccattcaaat taccatcaat caatttccca taaaaatcac
     8941 tataaccacc aatttgatga ttcaaaatcg ttttggccga ctcttttgga ggagtgattt
     9001 tatagataag ataagttgaa taacttgttg tatctttgac agtgttttta ttcctaactg
     9061 ctttaattgt aaatggtaca gcaatgagag caaataaagc gatgagagct aaaatatttg
     9121 cttttcgctt tttataaaga tttgcaaaca aatcagctac tgaataatgt tcaaacatga
     9181 tttttttctc ctttgtttag tagatactag ttttcctttg taagcatttt tgctataaat
     9241 ataatcacaa gaacaattcc ccagaattgc attgtaaata aattgaagaa actttctgaa
     9301 aagctgcttc ttggcataaa gaatagatta ttcaagatga gtagggataa agcaaatagg
     9361 attgtccttg agcgataggc tacttgcagc atggctataa ataatacgcc gagtaagaaa
     9421 ctaagcagaa agactccaat cataccatag tcggtataca actccatgat ataactactt
     9481 ccgataccat gccctttcag gtattccttg ttcaagacaa gataggatag attgtgggca
     9541 taactattac tatcaatagc tagttccaca ctattggttg tatgttcaaa ggcttttcct
     9601 ccgaaaatgg ctcccaaact cccccttgca aaataatcaa gaacaggacc aaaagtaaaa
     9661 ttacggaaat ctcggtaagg gaggctactg ttaaatagaa aacctcgagc cagaacacca
     9721 aaactagtcc cttgtttata gataaagtca agtaagatat cccagaaacc tgtatgggaa
     9781 acttggacat tatcccgtac ataattgagt actcccatcg ctaacatgag aataggagaa
     9841 cctacaaaaa tcgctaactt ttctttaaac ccaatccatt ttcctttttc agtttgctcc
     9901 cgcataaagt aataaacaaa agcaaataaa atacttaaaa taaagggatt tcgtgtccca
     9961 attgccaaat gaatagtatt agctgcaata aaggagacaa gcactgctgt ggcctgcaat
    10021 ttctttggct tggttgccag atacatacac attgcataga ccgtaaaggt agacaaaatg
    10081 taggtaaaat aaggcagttt actttcaaaa tttgcatagt aggcatagta ggaagtctgc
    10141 aaacgataca agagccgttc aaataaccga atgaaataga aaggataagt tagaagaaaa
    10201 actcctagtg atacaaagcg taaccgcttg atataaacct cttttagaga atttcctata
    10261 tttgctactt ttattttctt cctagctatg aagtaacgag ccagaatgcc tcctgtggtc
    10321 aagcccagaa tcgaaaccat gacaactata aaggcaaaac gataggctat tggatgatag
    10381 gtatccaaag caccatccct aaaataatca atggtcggtc ttgataccag aaatacaaaa
    10441 atggttaaat agaaaataaa atggattaag taatacttga tatcattcca acaagcaatt
    10501 aagctactaa ccaacaagaa caataaagta gaaagtaagc taacattatt attattaaac
    10561 agatacacaa ttccacttac tagcgtcaag gcataactga ctatggtcaa actaaataat
    10621 aatcgtttcc catcaatcac ttggtcaccc ccgttctaat gtaatttttt agatttttca
    10681 atatttttca gtaataagaa tcgatataag gaaatattta tgaatagggc caaagcacta
    10741 attcttctcc ccttacggaa aattggattc ctagaaatag caaaggcatg gccttttaaa
    10801 aaacgatgaa tctgagaata ggcttcaaac tgtttatact gatcatctag caacatctta
    10861 tccagaataa agaagtgggc ataggccaat ctgaaaaaag cgacctcttt caagtcagga
    10921 tagtttttca caacttcatt ataaaacttt tggtagatat caatataggc taaatccttc
    10981 tctgcatagg gtttggtcgt aatactatcc cctctatgga aatagtaata atagggttta
    11041 gtattaacca catacttctt ggccaacttg attaaatcaa aatggtaata ggcatcttcg
    11101 taaatcaacc ccttaggaaa ggatagggca gttgcaatct gtctcttgat tagcttattg
    11161 caaatcgtcc caggtatttt ttcacctatg aggtattcct ttagaaatgt ttgagaatca
    11221 cagacaaaat agtcatcctg attggctgac tgtgggcttt catcattagc atagacattc
    11281 atgacaccac agcttgaaac atccgcatct tcttgaacta attgctcata taagctctga
    11341 atcatttctg gatggatata atcatctgag tcaataaaaa tcagataatc cccgtgagcc
    11401 tgcttcatcc catcatttcg tgcttgcgac aatccttcgt tctttttatg aagcactgac
    11461 accctgtcat cttgttcagc gattgagtca cacaagcgac cactttcatc tgttgcacca
    11521 tcatcaacaa gaataatttc cagattttga tagatctgct tctgaatgga agctatcgat
    11581 ttttctaggt actgcgccac attatagact ggcacaatca cactaattaa tgcagtttcc
    11641 atgctactcc tctaatagtt tttctacttg ttcgatttgt tttgtaattg taaattgttg
    11701 aatgaattgg ctagcctcat cgacatcaaa gtttgaggca gaagtcatgt aattagtaat
    11761 cgcctgagct gcctcttgat tgctctcaat gatttgtcca aatcgtcctt cttgggataa
    11821 ttcctcagcc cctccaacgt ccgtagagat aaaagggagt cccagactca aggcctccac
    11881 atacactcca ggaaaacctt cttgtttaga catagacaag agaactttcg tctgagataa
    11941 atactgataa ggattttttt gataaccaag gaaatgtaca tagtcctcaa tcccatactc
    12001 tttgactcgt tttttcagtt cctcttccat atcaccagcc ccgataaaat agagatgata
    12061 gttttttccc tcttggtgta ataatcgtat cacttccact acacggtcag aacccttatt
    12121 ttcctcaatc cgtccgatag tacagatact ttgaggagca atctcgatat cgatcttctc
    12181 ttgagatttt tctagaatag tctgaaaatc atatccattg tagattatct gtaatttaga
    12241 agcataatct ggataaactt ccttgataga attgctggtc ttttttgaaa tccctacaat
    12301 tgtattcgca gcatccaact ggcttctatg tgattctctt ttagagctat ccttaagaag
    12361 ttcttcaata cttccatgaa tccaagatat cttcttgact tctcttcttt tagagaacaa
    12421 cagtggtgga ttcataatgg taaaagaaac ttcaacatca taatcatctt ttacaagcaa
    12481 acgacgagtc agtcttggaa aataaattct cattctccac aaaaaagctc gtaaccatct
    12541 ggtttggcga taatcttgaa gggattttaa aatgcgtaca tgctttggaa cagattcata
    12601 tcccttgtca aagtgctcca tttcaagaat atcaatatca tacttttcta gatccagatt
    12661 tgaaacaatg gttgatagaa tcttctctgc accacctcca agagaaaaag accacataaa
    12721 aaataagatt tttttcttag ccaccatatt ctcccttgta ttctgtataa gacttatcca
    12781 tatcagcgat gacagcatca tgatgcggta cctgcttgtc tgctggtgga ggcgtcatat
    12841 aatccccaaa agcagttctg agatagacat catagccgat tggaataggc atctctgttc
    12901 cttcaaatgg caagaaaaga ttgtcttcaa aagatgtgat tgggtacttg tttctcatgt
    12961 agccaggacc tgagcataat tctgtaatgc catcacaatc agccaaatca tacttagtca
    13021 tttctttctc agcttttttc cagatgcgat aacggagaga ttttggagtc aaacccagta
    13081 aaatgcgact tccccatttc atgagagcac catgcttttc tggaatagtt tgcgcacaaa
    13141 agagtgaata aatcaaggcc caacgaacct gttttttccg ctcagctgga tttttcggat
    13201 aataatccaa aggcaaaaca tccaaggtca gaccatgtgg caaatctaaa tcctgctgat
    13261 aaggcttgat acaggtggtt tccttgtcac gaatggtaat aaaaagatta cgatcaacaa
    13321 aatccttgtg actctttgac aagaaataac gttcatctgc ataacgaggc cataattctg
    13381 ctaatttctc ataatcttta cgaggcataa aaaagtctag gtcgtcgtcc caaggaataa
    13441 atcccttgtt tcgaagggca ccaatagcgc ctccgccaca gagataacag agcaaatcat
    13501 gttctttaca aaaggccaca aaatattcag ccatctccag actacgagcc tgaattgctt
    13561 ttaaatcagt catattgttc attattcttt ctatcgtatc gtttcattat accacaaaca
    13621 aggggtgaaa atctattgca gactgtaaaa aatcaaagcc tgactgctat ccaaatagct
    13681 atcaaacttt gatttttctg tcttatactc ttcgaaaatc tcttcaaacc acgtcagctt
    13741 caccttgccg taggtatagg taactgactt cgtcagtctt atctacaacc tcaaaactgt
    13801 gtttttagca gcctgcggct agcttcctag tttgcacttt aattttcatt gagtattatc
    13861 ttatctcaag cccatttgag cgagcttggt ttgatatttg ttttgatcaa ccagcaagcc
    13921 caagcctcca taaacatcat aggcatctac ccagtcaccc agttctggaa tcgtcaattt
    13981 ttcaatacca ttttttgctc catccaaaac agataaaccg tttgttagga ggaaagtata
    14041 gggtacgttg gttgaggtca tagcaaaaac ctttccaaga gcttcagaac cagtgaaaag
    14101 tttagtggga tctttaattt gctctaaaat tgctgttaaa acttgttgct gtctttttgt
    14161 acggccgtaa tccgcctcat catcatcacg gaaacgagca taattgagca gggtcgagcc
    14221 attcatctgc tgttttccga ctttaatggt ttgggttgga gactcagtct cggtagcgta
    14281 taaatcatct ccgactgtag cttctgttag gggacgccca ttcaatgttg aaaattgagc
    14341 atcaatcgtc accccatcag ggaaaagcgt gtcaatcgct gtggcaaagg cctggaaatc
    14401 aaccaaggcg tagtacttaa tgtccaagtc aaaattatct ttcaagactt ggcgaaccat
    14461 ttctgcccct ttttgcccct cttgttctcc taactcgtag gctacgttta acttgttatc
    14521 tgtctgtttt ctaccattaa tcacttgact ataaccatct atatagacca aattatcacg
    14581 catgaaactg actagcttca ttttcttatc tgagcccccg acatttaata ccataataga
    14641 gtcagttcgt gtctcaacac tgttctggcc gattcgacca tcagtaccca tgattaaaat
    14701 attaactcca tctctagtgt cctgaccatt aaagacttct acttgagctg cccgggcatc
    14761 agcagttttc tttgcgctag catcttggta accacgcaaa aacatgaata ccatggccaa
    14821 agccacacag accaaaagtg aaaaaatcac cataaaaatt cgtttaagac ggagcttccg
    14881 tcttttcttt tttggaggga aagagagtgc ttgtgatttg gattgtgagc gactccggtt
    14941 cgcatagctt ggtaagtcaa cctgctcttc tctttcttgt tccaagctag agctactatt
    15001 tcccctagca agagttagct tttcttgcaa ataggcaaac tcattttttt ctctctcatt
    15061 gagatagtga atatttttta gcaaataatc ataacgcaac tgctcatgat gacttaaggg
    15121 attttcttta ctcatcttct ctcctttcca tggtctgata ttggataaat aggataggca
    15181 cccagaattt tatactggat tccaatcgct tctaattctt tttgggcaaa gtggaccaag
    15241 tccttatcga tataatccac atcgataatg aaaaagtatt cacccagtgc tgtcttgagt
    15301 ggacgacttt caatttttgt caagtcaatt cctcgccaag caaaggtcga cagggcctta
    15361 taaagtgcac ctggaaggtt gtcaggtaat gtcaaggcca aactcatctt ttcagtttgt
    15421 gcttgcaagg gaatactagg cttttcagct cctagaaccc agaaacgtgt gaaattggct
    15481 tccatttcct gaatatcctc ggcaatcagt tccaatccat attcttcagc agaacttcta
    15541 ggtgcaactg ctgcaaaggg ctggtctgga tgttcggaaa taaaacgggc cgcataagct
    15601 gtactagctg ttacctcgat ttgagcctct ggatattgtt catcgatgaa tttctttcct
    15661 tgagccaagg cctgtggatg tgaaaaaatc ttttcaatct tagtatggcc tggaaccacc
    15721 atcaactgct gatgaatagg ctgaacgatt tctgctactg cttggatgtg agcctgatga
    15781 aaaagatagt ccaaggtttc atgaacacta ccctcaatag aattttcaac tggcaccaca
    15841 gaatagtcca ctaatccttg ctcataagcc ttgatgacat ctgtaatgtt ggcaaaagcc
    15901 tgcaattcct catgaggaaa agctgtctgc acaacgtggt gtgaaaatga tcccttggga
    15961 cctagataag ctattttcat cttagttcct ctataatttc ctctgggctt agcttggtca
    16021 catccaaaac ccgactagcc acttcctcat accaagcctg tctttcttga aaaatagcta
    16081 ctagttcttc cttgctatta tttagaaaaa gcggtcgctg attgtcctta tcagctgcga
    16141 tacgtaggta gagggtttca aaatctgctt tcaggtagat gttatctgta ttagtcttga
    16201 gtaagtcacg atttctctga gaaataacca ctcctcctcc agttgacacg acttggtctg
    16261 tttgtagtaa atcagctagg acttctgatt ctacatgacg aaaggctgct tctccctttt
    16321 cagcgaaaaa attcgcaatg gacataccta ggcgcttctc aatcagagca tccatatcaa
    16381 ggtaattagg gtccaagcct cttgcaatag tcgattttcc agcccccata aaccctaata
    16441 acaccttagc catgaatcaa gctctccaaa tcatcaaaga aactaggata gctggtattg
    16501 atggcttctg cacggtcaag ctccacctct ccatctgcaa ccaagagggc tgcgatagct
    16561 gtcatcatgc cgatacggtg gtcaccaaac gtattgactc tagcaccgtg aagagctgat
    16621 ttccctttga taatcatccc atctgccgta ggagtaatat ctgctcccat actatttaag
    16681 gcgtctgcca caacctgaat acggtctgtt tccttgacct tgagctcctc agcatccttg
    16741 ataactgtta caccttgggc ttgagtcgca agcagggcaa taatgggcaa ttcatcaatc
    16801 aatcgtggaa tcaaagcgcc accaatctct gttcctttca agtcagaaga ctcaacaatc
    16861 aaggtagcag atttagcgac tggatcgatt tcagttattt ccaattttcc acccatggca
    16921 cgaatgacat caataatacc ggtgcgagtt tcgttgatcc ccacattctg cagcactaga
    16981 cgagaatttg gagcaatcaa acctgcgact aaccaaaagg ctgcactgga aatatctcct
    17041 ggtacgacca ccttctgtcc tgtcaatttt tgtggcccct ggactgtgat tttcttacca
    17101 tccacactta aatgaccacc aaattgttgc aacatatctt cagtatgatt acgggtgtac
    17161 tctttttcga taataactga ctccccctta gcttgtaagg ctgcaaacat caaggctgac
    17221 ttgacttggg cagaggcaat tggcaactca taatgaatag gtcttaggtt tttcgtccct
    17281 tttaagcgaa ggggaggcaa gtctcgttca gtttgccctg aaatgctgac gcccattttt
    17341 ttcagtggaa gggtcacacg gtccatagga cgtttggaaa gactatcatc tccaaacatc
    17401 tctacttcga aatctgcacc agcaaggaca cctgaaatca ggcgaatcga ggtgccagaa
    17461 tttcccatat taagggcatt ttgtggcgct tttaagccag ccatgcctac accttgaatg
    17521 gtaataaccc catctttatc ctcaatttca acaccaaggt cacgaaaaac ctgcatggtc
    17581 gaaagaacgt cttcacctcg cagaatatca taaaccttgg tctcaccctc agccaaactt
    17641 ccaaagataa tggaacggtg gctgatagac ttgtcacctg ggacgcggat actaccatgt
    17701 aaatggcgaa tgtttgtttt tagtttcata ctggacctca tacttgcaat acttttacct
    17761 attttatcat aaaaagtcag aaattcctta aaaattcctg actttaggat cgttcttttc
    17821 ttatttcagc aattctgaaa ctggttcaaa aacaattttt tcaatgtcag aaaggtaaat
    17881 ggccaattgt tgttgcttgg taaagaattc tgacaagagg ctatttcctt gaatctgttt
    17941 accaaagcct tccatcttag cttggaagga cgcatctggc atttgacctg tctgtgctag
    18001 tttttgaatt tcctcttgaa aggcaagata ttctgtaaag attttgcttg cctcagcatc
    18061 tgctgcaatc gcatctttag ctgctttaac agccttgtat tctggtaatc cgcgtagacc
    18121 gcgactgagt tcgtttgcac tatcgtaaat atttgacatg ttcttctcct tatttgatga
    18181 cgactgtata gtcggtattt tctgttatga gatgctcagc tctttccaag tcttgagcat
    18241 ttttaaatga aatttgtagg attccgtgaa tatcctcacg attttcctcg ttgatgtgga
    18301 tgttaaccaa ggaagttcca cgtagcagtt ccaaaatccg caggatgaca tcttcttcat
    18361 caggaacgtc aacatagagg tcgtaagagc tatccacacc accacgctta tggatttcca
    18421 tggtctggcg ttgttcacgc gcttggttaa aaaagttcca aatttgctct tcatctccct
    18481 tactaatggc ctgaccaatc acttccaaac gttccttgaa atcctcaatt ctatccagaa
    18541 tggtctcgct attggacaag agaatggagg tccacattcc tggctcgctt tccgcaattc
    18601 gggtcatatc tcgaaaacca cctgccgcaa agcgccttgc catctcatgc tcttgagcat
    18661 agaccgcagt ctgctccatg agactagaag ccaaaatatg aggaaaatgg ctaatctgag
    18721 aagtgacacg atcatgctcc ttggcatcaa tctcgataaa acgagcatga agacctgaaa
    18781 gcagatcctt catttcctta agcgtgtcct gacttgtcag gcttgaaggt gtaaagatat
    18841 aataggcatt ttcaaaaaga ttgacatctg ccgaagcagc ccctgtcttg tgactaccag
    18901 ccatgggatg ggccccgaca aagcgaacag acttgccagc caaatactgc tccgccgcat
    18961 ccacaatggt tgacttggtc gaaccagcat ctgaaataat aacgccttct cgcaaatcca
    19021 aattggccaa ctccttaatg aaagcaatag tttgtttgat tggcaagctg aggataatga
    19081 catctgccaa aggagcaaaa ctagcaaaat catccgttgc acggtcaatc ataccttctt
    19141 tcaaggcgat atctctcgaa gcttgactac gattataacc taaaatttca taatctggat
    19201 gatcgcgttt gataccaagt gccatagagg ctccaatcaa cccaagacct gcgatataga
    19261 ttgtttttgc cataggaact ccttaatagt tctttgtata gtctcggtgt ttggctaccg
    19321 cttcttttag ttcctcaaga ttatctgatg agaatttttc gaggatttct tgcgccagaa
    19381 ccgttgctac aactgcttcc atgaccattc ctgcagctgg aagagcagtc ggatcacttc
    19441 tctccacggt tgccttgtaa ggttcgtggg tttcgatatc cacactcata agaggtttat
    19501 aaagagtagg aatgggtttc atgaccccac gaacaacgat gggttgccca ttagtcatac
    19561 caccttcaaa accacctaga ttattggtac ggcgagtata accgtcttct ttagaccaga
    19621 gaatttcatc cataacttgg ctgcctttac gataaccagc ctcaaagcca agaccaaatt
    19681 ccaccccttt aaaggcattg atagagacaa cagcttgagc caatcttgca tccaattttc
    19741 tatcccattg gacataggaa ccaagaccaa ctggaacgcc tccgacgact gtctccacaa
    19801 ccccaccgat ggtatcacca tcacgtttga tttggtcaat atagtccttg atttcctgtt
    19861 ctcgttcttg gttgacaata gaaacttcag actgggcagc tctttgctta atttcagcga
    19921 ctgtcagatt ttcaggaaca tctatttcct taccaccaaa gaccacgaca tggttggcaa
    19981 tctccatatc cagctcagcc aagaggcgtt tggctactgc accaactgcc acccgcatgg
    20041 tggtttcacg agctgatgaa cgctccaaag aatttcgcaa atcatcaaaa cggtacttaa
    20101 tccccccaac caaatcggca tgacctgggc gaggatgagt aattttccgc ttgcttttaa
    20161 ggcggtcttc aatgtcctcc gcagacatga tgtccagcca tttctggtgg tccttattga
    20221 tgacatccat agtaataggc gcccctgtcg tcttcccgtg gcgaacaccc gaagtaaaga
    20281 caacctggtc actctcaatc ttcatacgac caccacgacc gtagccaccc tgacggcgtc
    20341 taagatcctc attgatatcc tcagctgtca atggaagtcc agctggaatt ccctcaataa
    20401 tagctgttag acgggggccg tgtgattctc ctgcagttaa atatctcata cactctcctt
    20461 attttaccaa gtagtctttc atctcttcca gagaaactgg gtgaatggtc gctgaaccaa
    20521 gctctggcac caagaccaat ttcaaggtgt taccacgcgc tttcttgtca tgagtaagag
    20581 cctgataaag cttgtcaact ttccaatttt catagtcaac aggcaagccg aatttctgac
    20641 acatctctgt gatagattgg gtaatgccag ctggcatgag gcctttttcc tcagcaacct
    20701 tggaaatctg taccattccc atggcaacag cctctccatg catgaccttg ccataaccgg
    20761 cagtcgcttc gatggcatgg ccaatagtgt ggccaaaatt gaggtaaaga cgaataccat
    20821 tgtccaactc atcttcaacc accatcttgc gcttcacctg acaagaatgt tcaatcaagg
    20881 tctctgcatg ttccaaaata ctctcaacag aaccattcag tcccgtcaag agagcccaca
    20941 gttctggatc ctcaatcaag ccatacttga taacttcacc catcccttca atcaactctc
    21001 tttttccgag ggtttcaaga acaagtggat caatcagaac cccatctggt tgggcaaagg
    21061 tccccaccat atttttagca aatggtgtgt taacgcctgt ctttccaccg atagaagaat
    21121 caacctgagc tgtcaaacta gtcggaatct gaacaaagtg aataccccgc atataggtag
    21181 aggctacaaa gccagccagg tccccaacaa cgccaccacc aagagcaacg attccatcgc
    21241 tacgagtcag accttgcttg actagaaatt catagacttt ctgaacagta gttaaattct
    21301 ttctttcttc accttctaag aaatcaaaaa cagctacctg aaaaccagca tcttctaggc
    21361 tgagcttgac cttctctgca tagagagagg ctacatggtt atctgtcaca atgactacct
    21421 tttgcggttg ccagagttct cgcaaccact gaccagcctg ggccatacaa cctttttcaa
    21481 tctgaatatc ataaggatga tgaggaatat cgattctgat tttcatagga gagtctccct
    21541 ttctttattg atatttttct gttaaagact gccaaatctc ttctgtcggc attttcttgc
    21601 ctgtccacag ttgaaaagct tctgcagctt gatagagcaa cattcccaga ccattgactg
    21661 ctggattgcc ctgacttcta gcccatttca aaaacggtgt ttcaaagggt tggtatatga
    21721 tatctgcaac taagagagtt tctggtaaga ctatgttttc aggaacagga gaggattggc
    21781 catccatgcc cacactggtg gcattaacta gcaaatccga ctcggcaatc cttgcttgca
    21841 gttcagaaac atattctaaa gcacacaaat ccactttaaa gcctgtctgc tcctgtaact
    21901 tgtctaggta aggtcttgtt ttttccatag aaacggaacg aacaaagacc gaaatctgac
    21961 tgacgccatc caaaatagcc tgtgccaaga ttgatttagc cgcaccacct gcacccagca
    22021 gggtcatctt tttacctgaa attgtaaaag aaggcaagca cttaaaaaat cccttgccat
    22081 ctgtattata tccaattaaa ttgccattct cattgacaac cgtattaacc gcaccaatca
    22141 agcgcgcttc atcgctcagc tcatccaaat aaggaatcac ctgctcctta tagggcatgg
    22201 acagattgat gccaaacatc tggtagcgac gaatattggc cactgtttct accaagtcac
    22261 tcgcttcaat ctcccaagcc acataagcac cgttggtagc tgtcgcctca aaggctctat
    22321 tgtggatgaa gggagaaata gaatgcttaa taggattggc aacaactgca gctaaacgtg
    22381 tatagccatc aagcttcatc caaaatctcc ctgatttttt tcatgctagc tagagaaatc
    22441 tgcccagggg cactaacctc atccagactg gcaaaagacc aactcgaacc agtcacatcc
    22501 gcagtgatac gagagacctt gcccacctta cccatagaaa tggtcacata ttcctgttca
    22561 ggattgagcg ttttaaagcc tcgtgtatag ttcatcaagt ctaagacatc ctgctccgtg
    22621 tgagccatca ccgcaacctt aacaagtttt ggatttagga tcgtcaactc tgacaagatt
    22681 tccatcatgt tctcaggtgt ttcttggaaa ttatggtaac tcaaaacaag atttgggaag
    22741 tccagcattt cctcaaaaac atccttgtag ctatagtact caaaatcaat atagtctggt
    22801 tgatagagtt gcgcaacttc cttgattaga tggatatact cttctggaga aaggtcgatt
    22861 tctccacctt cggagcgagt tcgtagcgtg aaaaccaact cacggcctgc gaatttttca
    22921 aaaatggctg gagctacctg caaaatcgct tctttaggca gatagtcggc acgccattca
    22981 atgatgtcgg catccaggta cctcgtggca tccagagcct gagcctcctc taaacttctt
    23041 ggcattactg aaacgattaa tttcatttac taaccttcat actaatcacc ttgaggtaat
    23101 tactactttc atctttttta ttataggcaa aatctgctgg aagaccatat ttgtttaaaa
    23161 tctggtaact tcttcctgca aagcctttat caatttgttc tgtaaatttc tgacgggaaa
    23221 cattggcagc attggtactg gcaatgataa tccctcccgg atttaaaatc tcaagactct
    23281 gggaaatcaa cttgtgataa tccttggcca cagagaaagt ttgtttttta ttccgagcaa
    23341 agctaggcgg atctaggaca atcacatcgt aggtcaagtt tttgcgtttg gcatatttga
    23401 aatactcaaa gacatccatg actataaaac gacgctcgtc tgtgctgagc ccatttgcct
    23461 gaaaatgcgc ttgagacaat tctcgtgaac gtttggctag atcaacagaa gttgtctggc
    23521 tagctcctcc catggccgca gctactgaaa aagccgctgt gtaggaaaac atattgagca
    23581 aggatttacc catagccaag ccgtcaacta aactaccgcg aacctcatgc tggtctagga
    23641 aaattcctgt catcaagcca tcattcataa agacttgata caggacacca ttttctaaaa
    23701 cagtgaaaaa gtcaggtgct tcttgaccat aaacatgggc agattcatag tccaaaccct
    23761 taaagcggat tttctcataa gcccctaaaa cctcagggaa aacctgtcta aaggcttctg
    23821 atatagtctg acgaatctga taaacataag agttatacca agaaaagacg gcgtagtcgc
    23881 cataaaggtc cactgtcaga cccccaaagc catctccctc ttgattaaag agacgaaagg
    23941 cagttgtcaa atcatcttga tagtaggcgt ttctcttttc tttggctttt ctaaacaacg
    24001 tttcaaagaa agcttgattg aaggccacct tgtctttgct gacaaaccag cccaagccct
    24061 tgttttgctg agaaaggtag gcagtcccaa gaaagtttcc ttcctgaccc tgcacctcta
    24121 cttcctgatc cttaagattg acattctcaa gatcactggc ttctagtaaa actagcccct
    24181 tagcaagctt cttttcaacc cttttgctga ctcttattct attcataact accattatat
    24241 caaactttta gacaattctc aaaaaagaaa ctacccttgc ttttttactc ttcttttaaa
    24301 aaatggtata ctagacttcc tgcaaaacta ggaagtaaat gtgtaagaat cacaataaaa
    24361 aatgctcttc cgtcttggag gagcatttct ttttatcaac gaaaatcaaa taacaaacta
    24421 tgaaactagc ctcaggttaa ctgtgagatt ataggtagag aggttgaatc agcaatatgt
    24481 gtctgtcaaa tttagtgaca aaggtagtag aagaaagatg aagaaataaa tctgcttcag
    24541 tagatatctg gaaaatttga ttttatagaa aagccttttg ttacaaactc aatatactat
    24601 caataaataa tattatagaa gcaacaataa ttaaaatttc acctatttgc atcattctat
    24661 ttcgaactct aaatatatgt tctatcaaaa atacttggat cacacacatt ataggaatta
    24721 acgtttttga aattgaaaaa tatcccaata aataaactat aaacaacaat aatagaacta
    24781 tattatattt cttattcaaa acattcctcc ctatattttt gattaccaat cttaatcatt
    24841 tacaactaca ttctaacaaa ctataaaagc gtttgtcgaa ttgaatttat caagcaagca
    24901 accaactatc tcatcttttt tctatttctg ccaatatgcg tgacaggtaa taatgatagc
    24961 caaaaatagc aagagcaagc aagacgataa gagctcctac tcccaagttg atggcaagga
    25021 taggggagag agactgaacc aagaatatgc tcccaattac aagggccatc aggattgcac
    25081 tataaataaa caataaaact atggcgacta tgccatttga acgattcacc aggtccgtaa
    25141 tgctactcca attggttgac agatttttaa cgtccttaaa gtaatggtgg caagaaagga
    25201 tgacactggc aatgatccag actacaagaa ggtaaatcat cgaaaggatg gacaagccta
    25261 gatatagaga aagaccgagc aaagtcagaa ctggtaaaaa ggactgaaca gcaaagataa
    25321 tccaaaattt cactttcaca taacgagcaa agtcaaaggg taaactcttc agaaaatcaa
    25381 cattttccct ctccaaggac aaggcaattg aatgcaggct ggtgatattg ttattgacaa
    25441 ctgctataaa cactcctaca aaaaacaagg gtaaccagta tggaggatga atgtctggaa
    25501 ctatctgaga atctcggatt ttggaaatca gactgatcat catgagataa ggaaggaaag
    25561 cacttgtaaa aagcactgta atcacaccag tcccctatcc caagagggtg aggtggtagc
    25621 gtaaaaccat acggaaaaag ccctttttag tagttgaaat cctctccttg ctgcgacgtt
    25681 cttttttgac cttctcctca ctgttaagca ggatcacgtc ataaaaacga ggaaggacct
    25741 tctttttggt cagataaagc aggaagagag ttagtcctat ccaagcgagc agacccacta
    25801 aggcttctgt cgaaaaaggc tccactgcta ttttgtaaaa gatatgaaga ggataaagga
    25861 gaaatggaat gtctctaact ttgtcaacaa tacttccaaa agtcgactga agaaagaaga
    25921 taaatattaa aggtatgaga actcctatcc caatcatcac attcgaaaaa atagactgat
    25981 actttctgaa gaccctagtc tgagccaaga aatgtactgc cactaccgtc actaaagtaa
    26041 cagagacaaa taataaggtc aaggacagta gcatcaaagg caaacccagc caaagagaag
    26101 gagctagact aatatagagg gctagaaaat aagctaggat tggtacaatt ccagttagag
    26161 ctggcaagag gacagacaga cctttggcca ttataatctc tgattcttta aaggcatagg
    26221 gcctatagga ggccaggtcc ttactctcat aaaagacatt gtaaaaggca gtgaaagaag
    26281 ttgaaaaggc cagcaccagt aaaatagcaa ccatcgagct aaaataaata ggtatttcct
    26341 caaaaggaaa atgaatggct atattactaa aacagatgag catcaagaga ctggaaaaaa
    26401 tgtaagaact taggactcta gcagaaacat ttactttttt cccaggattc ttagcctgct
    26461 tctttcgtag attagccaga ttagcttctt gagatgaata gaggatattg atatcaacta
    26521 attttttaat gaccttgaga cgcatccgca acctcctctt ttctaccagc aagactaagg
    26581 tagatacttt ccaaaaactg gtctgggtgg tctttcctca agttctctac actaccacaa
    26641 tagatcaaat gccccttttt caaaatagca atccgatcac agacttgctc ggctacctca
    26701 aggacatgag ttgaaaacaa gaccgtcttg cctttttgtg catgttcctt catcatttgc
    26761 ttcaaatcaa aggcggcctg gggatccaaa ccagtcaagg gttcgtccaa aacccaaata
    26821 tcaggagcag acaagagtgc cccaatgaca aagactttct gacgcattcc gtgagaaaga
    26881 gtttcaataa cctgatagcg gttttcagca aaatcaaaaa cgttcaatag cctagctaga
    26941 ctagtctcca agtcagagct agtcagatca taggatgaag cgatcaattc ccaaaattca
    27001 ttggccgtta agcgtaaaaa taagtcaggc gagtctgcta cgtagccaat ctttcgtttg
    27061 atcgccaagc gattttccga taactcctga ccgtctacca aaatacgacc actgctgggt
    27121 gaaatgatac tgactaggga ttttatggtg gtcgattttc cagccccatt atgaccaatc
    27181 aagcccataa tctctccatt ttcaatctgc aaattgagat tactcaaggc ctctttatca
    27241 ccatacaact tactaacatt ttgaaattca atcatgggac aactcctatc tttatctgta
    27301 ttatacatcg ctatactagc actttgatac aaaaaaatca atactttatt ttaagtagtt
    27361 aaaatagttt ccttctatct tacgcaaacg tttgcgccga gagatacttt atgatagaat
    27421 aaagaacaag attgacaagt aagaggaaac atcatgcaaa atcaaacact catgcaatac
    27481 tttgaatggt atctgcccca cgacggtcaa cactggacgc gtctggctga aaatgctcca
    27541 cacctagctc atctggggat cagtcacgtc tggatgccac cagccttcaa ggcaaccaac
    27601 gaaaaagatg tcggctatgg ggtctatgac ttatttgact taggagagtt caaccaaaaa
    27661 gggactgtcc gcaccaagta tggtttcaaa gaagactatc ttcaagccat tcaagccctt
    27721 aaagaacagg gaattcaacc tatggccgat gtagttctca accacaaggc tgctgccgat
    27781 aacagggaag cctttcaggt tatcgaagtt gatcctgtag accgtacagt tgaacttgga
    27841 gaacccttca ccatcaatgg ctggactagt tttaccttcg atggtcgcca agatacctat
    27901 aatggcttcc actggcattg gtaccacttc accggtacag actacgatgc caaacgcagt
    27961 aaatctggga tttatctgat ccaaggggac aacaagggct gggctaacga ggaattggtc
    28021 gataacgaaa acggaaacta cgactacctc atgtatgccg acctagactt taaacatcct
    28081 gaagtcatcc aaaacatcta tgactgggct gattggttca tggaaacgac tggtgtagct
    28141 ggtttccgtt tggatgccgt taagcatatt gactctttct ttatgcgcaa cttcatccgc
    28201 gatatgaagg aaaaatacgg tgacgatttc tatgtttttg gtgaattttg gaacccagac
    28261 aaggaagcca atctggacta tctcgaaaaa acggaagaac actttgacct tgtcgatgtt
    28321 cgtctccacc agaatctctt tgaagccagt caagctggcg caaactatga ccttcgtggc
    28381 attttcacag atagcctggt tgaactcaag cctgacaagg ctgtgacttt tgtcgacaac
    28441 cacgataccc aacgaggaca agcccttgag tctaccgttg aagaatggtt caagccagca
    28501 gcctatgccc tcattttgtt acgccaagac ggccttccat gtgtctttta cggagactac
    28561 tatgggattt caggccagta tgctcaagaa gatttcaaag aaatccttga ccgcctccta
    28621 gccatccgaa aagacttggc ctatggagaa caaaatgact actttgacca tgctaactgt
    28681 atcggttggg tacgttcagg tgctgaaaat caatccccaa tcgcagtcct tatctcaaat
    28741 gaccaagaaa acagcaagtc aatgtttgtc ggtcaagaat ggactaatca aacctttgta
    28801 gatttacttg gtaaccacca aggtcaagtt acaattgatg aggaaggtta tggacaattc
    28861 cctgtctcag ctagatccgt aagtgtctgg gcagtcaata ccatctaata gctcataata
    28921 accaagctag gtccaagcgg atttggcttt tttgtattca caaaaagacc tacccaaatg
    28981 gatagatctt tacttgatta caatttacct gctactgcat ccaacaattc ttggatctta
    29041 gcttggttgc ttcctcctgc catggccatg tctggtttac caccaccacg tccatcgatg
    29101 attggtgcta attctttgac aaggtttcct gcatgaaggt cttttgtctt gcttgctaca
    29161 aggacattga ctttgtcacc gatagcggca actaggacaa gaagatcaga gtagtctttt
    29221 tgtttccagt tatctgcaaa agtacgaagg gcaccggcat cggatacaga cacttgacta
    29281 gcaatgtaac gatgaccgtt gacttcctta gcatctttga agatatcgcc tgcggctgca
    29341 gctgcggctt tttctttcaa ctcagcattt tctttttgaa gttgacgaag ttgttcttga
    29401 agtccttcta ccttgtgagg tacttccttg acttgaggtg ctttcaaggt tgctgcgaca
    29461 gctttaagag catcctcttg ttcacgatag gcttcaaagg cttccttacc agtcactgcc
    29521 aagatacggc gagttcctga accgattcct tcttctttga caattttgaa gagaccaatc
    29581 tcagaagtgt tgccaacatg agtaccacca caaagttcaa tagagtagtc accgatagtc
    29641 acgacacgaa cttccttgcc gtatttctca ccaaagaggg ccatagctcc catttcttta
    29701 gcagtgtcaa tatccgtttc aactgtcttc acttcaagtg cttcccaaat tttctcgtta
    29761 acttgctgtt caatcgcacg aagttcctca gcagttactg cttggaagtg ggtaaagtca
    29821 aagcgaagga attcaacttc gttaagagat cctgcctgtg ttgcgtggtt tccaaggata
    29881 ttgtgaaggg cagcgtgaag caaatgagtc gcagtgtggt ttttcatgac acggtgacgg
    29941 cgattgctat caattgccaa ggtatattct tggttcaagg caagcggtgc aaggacttca
    30001 actgtatgaa gggcttgacc atttggggct ttctgaacat tggtcacagt agccacaatc
    30061 ttacctgact catccaagat ttgtccgtag tcagctacct gtccacccat ttcagcataa
    30121 aatgacgttt ccgcaaagat aagagaggca gttccttctg aaacagctcc tacttctgca
    30181 ttgtcagcaa cgatagctac caatttagaa gacaattggc tagtattgta gttgaagaca
    30241 ctttctacag tgatgttttg aagagtttca ttttgcatac ccattgagcc acccttgaca
    30301 gctgacgcac gcgcgcgttc ttgttgttct ttcatggctg cttcaaaacc ttcacggtct
    30361 acagtcatac cagcctcttc agcaatttct tcagtcaatt caactgggaa cccataagta
    30421 tcatagagtt tgaagacatc tgaaccagcg ataacagatt gacctttttc tttcaagtct
    30481 gctacaatgc cttgggcaaa gtgttgacct gagtgaaggg tacgggcaaa tgattcttct
    30541 tcgctcttaa cgattttctc aataaagtca cgtttctcaa gcacttctgg gtagtagctt
    30601 tccatgattt ttccaacagt tggaaccaat ttgtaaagga aaggctcgtt gattcccaat
    30661 ttttgaccat gcatagaagc acgacggaga agacgacgaa gaacataacc acgaccttca
    30721 tttcctggaa gggcaccatc accgatggca aatgaaagtg aacggatgtg gtcagcgatg
    30781 accttgaagc tcatgttgtc gccatcttgg tcataaacct taccagacaa tttctcgact
    30841 tcacggataa tcggcatgaa gaggtccgtt tcaaagttgg tcttagcccc ttggataacg
    30901 gccaccaaac gctccaaacc agcgcccgta tcaatgttct tatgtggcaa ttccttgtat
    30961 tcgctacgag gaacagcagg gtctgcgtta aattgtgaca aaacgatgtt ccagatttca
    31021 atataacggt cgttttcaat atcttctgca agcaggcgaa gaccgatatt ttctgggtca
    31081 aaggcttccc cacggtcaaa gaagatttct gtatctggtc cagaaggtcc cgcaccgatt
    31141 tcccagaagt tgtcctcaat tggaatcaag tgacttggat ccactcccac ttcaatccag
    31201 cggttgtaag aatctttatc gtctggatag taggtcatgt aaagtttttc agcagggaaa
    31261 tcaaaccatt cagggcttat caaaagctca taagcccaag tgatagcttc gtcacggaag
    31321 taatccccga tagagaagtt ccccaacatt tcaaacatgg tatggtgacg cgcagtcttc
    31381 cctacgtttt cgatgtcgtt ggtacggata gccttttggg cattggtaat acgtggattt
    31441 tcagggataa tggtcccgtc aaagtatttc ttaagggttg ctaccccaga gttgatccac
    31501 aaaagagttg ggtcatttac aggaaccaaa cttactgatg gttctactga gtgacctttg
    31561 gtcgcccaga aatcaagcca catttggcgt acttgtgcac tagatagttg tttcatattg
    31621 tctccttatt tacttgttta atgtgattgg ctttccagca tttccacata gtcaatcgcg
    31681 acacagaggg aaatgactag gtctgcataa gcgtcttcaa gaaccgttac ggtataggta
    31741 gaggtcagat ggaagagttc cttcttaatt tccgcaatca actgatcgcg atcatccagc
    31801 aatttgaaat tcaaatccca gatattgccc tcgatacgaa gacctagatt atcaaactca
    31861 tacttatctc gccaaaaggt caacttctta cgaatgacaa aactcgagcc atccagaagc
    31921 tgaatctcaa aacgaggaag caaggtcaag atttctttac tgatctgact gacttgttca
    31981 ccagccgcat catagatggt aaaagttttg ggaatcttaa aaaatgatcc ctccacctga
    32041 taggcaattt ctcccctgtc atccttgata gcgaagcgtt cgcctccaag acgaaacttt
    32101 tgtttgacaa gaaatgtttt catcaacacc tccaaaaatc aaaagacaag ctcatatcac
    32161 gaagggcgaa aaaccgcggt accaccttca ttcaatgaac ttgtcattct cttgttctta
    32221 tgcaattgta tgattgagta gcatgacttc ctagcttaga tggctcgcag caccgccatt
    32281 tctctggact aagacaagtg aaaatcaatt ctcaactttc ttattatatc gtttttttaa
    32341 tcttgcgtca actggaaatg atctccgttg aattagacca attccctaca tctctgatta
    32401 cttttccagg atatattttt tcttactgcc gtttttcttt ttatcccaaa ttttcatatt
    32461 actaaacaca gctactagaa tatttccaaa tataaaggtg cctatcaccc aatatatgga
    32521 ctcagttgtt aggtattgtc gatccaagcc atcctttaaa tggaatagta tagcagtttg
    32581 gttaacaatc ataaaggttg gccagaaact tttgttgaaa aaagtagaca ttttcattat
    32641 ttgttgccgc tttctgtaag gttaatactc aataaaaatc aaaaagcaaa ctaggaagct
    32701 agcctcaagc tgtacttgag tacggcaagg caacgctgac gtggtttgaa gagtataggc
    32761 ttagtatact actaggcaag caaataagca aataaacaac tagaatagaa aaagataggg
    32821 ctctaaaaac tgacttctat tccttaaaaa cgaaccagct tgactgattc gtcttcttac
    32881 gtttatctcc tacttccgat acattttaaa ctgtaggaag aggtcgctat atttccctgt
    32941 ccatttatgg tcaaatttct cataaatttc taggtgtttc atggtttcaa catcgggata
    33001 gaaggcctta tcttcctttg tttcctctgg gagcaattcc ttcgctggta tgtttggtgt
    33061 tgaatagccg acatactccg cattttggag agcattttca ggtttcaaca taaagttgat
    33121 aaaggcatag gctgagtctt ggtttttaac tgttttggga atgaccatat tgtcaaacca
    33181 aagattgctg gcctctgtcg gtaccacata acgtagattt tcattttttt ctaacatttg
    33241 gctggcttca ccagagaagg tcacgccgat tgcaacgtta ttctgaatca tatagccctt
    33301 catctcgtcc gcaacgatag ccttgatatt tggagtcagt ttgtagagct tatccactgt
    33361 ctcttccaac tgctgcagat ccttggagtt gaggctgtag ccgagggaat tgagtcctag
    33421 tcccagcacc tcacgcgccc catcaaagag catgatagaa ttcttatact ccggcttcca
    33481 aaggtcatcc caatgctcag gcgcttcatc taccatggtt tcgttgtaga caattcctaa
    33541 ggttccccag aagtaaggga tggagaattt attacctggg tcaaaggact ggttgagaaa
    33601 ctctggtccg atattttcga ttccttcaat ttttgaataa tcaagcggaa ccaagaggtc
    33661 ttcgtccttc atcttgttaa tcatgtattc acttggaatg gcaatatcgt aggtcgttcc
    33721 accctgcttt atcttagtgt acatggcttc gttggagtca aaagtctcgt actgaacttg
    33781 aattcctgtt tcttctgtaa actgagtcaa gagttcagga tcgatatagt ctccccagtt
    33841 atagataacc aatttttgac tatctcgact attgatttta ctatctaaat gagtcgcaat
    33901 tccccacaag acaaggataa tcgctgcaat tcctgctaaa aatgaataga tttttttcat
    33961 gcttgctcct ccttctcacg agagataaag taataaccta caactaggat aatactaaag
    34021 agaaagacta gagcagacag ggcattgatt tctaaggaaa tccccttgcg agcacgagag
    34081 taaatctcga ctgatagggt tgaaaagcca tttcctgtta caaagaaggt cacggcaaag
    34141 tcatctaacg aataggtgaa ggccatgaaa taaccagtaa tgatagacgg agtcaggtaa
    34201 ggaagcatga tttccttgaa catctgaaat tgactagctc ccaagtcata ggccgcatga
    34261 atcatgtcgc cattcatttc cttgagtcga ggcaagacca tcaagaccac gataggaatg
    34321 gagaaggcca cgtgactaga tagaacggtc aaaaagccaa gtgaaaactt gagttgggta
    34381 aagagaatca agaagctagc accaatcata acgtcaggcg caaccatgag gatattattg
    34441 agtgatagaa aggcttcttg gtatttctta cgagactggt agatgtaaat ggcaccaaaa
    34501 gtcccgataa tggtcgctat caaggctgat aggaaggcca agaaaaatgt ctgagccaaa
    34561 atcagcatga gtctcccatc tccaaacatg gtttcaaagt gagtccagct aaaacctgta
    34621 aagctattca tatcatcacc agcattaaag gcatagccaa tcaagtaaaa gataggcagg
    34681 tagaggacca gaaagaccag tcccagataa aggttggcaa attttttcat cgttctctcc
    34741 tttccttagt cacccacatg gtgatgaaca tggtcaggat gagaatcaca ccgatggttg
    34801 aacccatacc atagttgtca ttggttagaa aattctgctc aatagccgtc cccaaggtga
    34861 taacgcggtt cccaccaatc aaacgggtca gcatgaagag actcaaactt gggataaaga
    34921 ccgactgaac cccacttcgc acaccgttca tagatagagg gaagatgaca tgacggaagg
    34981 tctcccactt agttgcacca aggtcataac tagcattgat gagattatta tccatgtcgt
    35041 ctaagacatt gaaaatcggc aaaatcataa aggggagctc gatgtagctt gcgacaaaga
    35101 taaaggaaaa atcggtaaaa agcaactgtt gtgaaccaat tccgataaat tccaagaatt
    35161 ggttaataga gccattttga ccaaaaatcc cgataaaagc ataggcttta aggagcaaat
    35221 tgatccaggt aggaaggata atcagcatga gccagagttg acggtgcttg agacgggtca
    35281 aaaagagggc tgttggatag ctgataagca aggtcacaaa ggtcacaatc cctgcataaa
    35341 gcactgagtt gaaactcatt ttgaggtagg tcaagttttg tgacgcaaag taagatttat
    35401 aattttctaa actaaactgg ccttcaatgt tgaaaaagga ttgtccgaaa atcaagacca
    35461 agggtgccaa tacaaagagg gcaatccaaa gcatgtaggg cactacaaag agtttagagc
    35521 ttgttttctt catctctttc ctcctcgatc gcattgatca gacctgcttc ttgctcttcg
    35581 atttccacgt attcttcgat acgagcatcg aactcttctt cggtttcatt gagacgcatg
    35641 atgtggatgt cttctgattc aaagtccaga ccgatttcct cacccacgat ggccttacgg
    35701 gttgagtgga tcatccattc atttccaagt tcgtcatagg cgataatttc ataatgaact
    35761 ccacggaaga gctgggtgtc gaccttaact tggagtttgc cttcttcagg aagggtaatg
    35821 cgcaagtcct ctggacgaat aacgacctca acaggttcat ttggcttcat cccaccatca
    35881 accgcttcaa agcgtttgcc gttaaattcg accaagtagt cctcaatcat ggtacctggc
    35941 aagatgtttg actccccgat aaaggtggca acaaagtggt tgattggctc atcgtagatg
    36001 tccacagggg ttccagactg gacaatctcg ccatcattca taacgaaaat ccagtcactc
    36061 atggcaagag cttcttcctg atcgtgagtg acaaagacaa aggtaatgcc caatcgttgt
    36121 tgtaattcac gcaattcgta ctgcatgtct gttctcaatt tcaagtccag cgctgataaa
    36181 ggctcgtcca acaagaccac acggggttgg ttgatgatag cacgggcgat ggccacacgc
    36241 tgacgttgtc ctccagaaag tttgcggatg gaacgttttt cataaccttc caactgaacc
    36301 atcttgagaa cttccgctac acgctgctcg atttctttct tatcaatttt acgcaagcga
    36361 agtggaaagg caacattttc aaacacattc atatgtggga acaaggcata ggattggaag
    36421 acggtatgta cgtcgcgctt gttggttgga atatcattga tacgaacacc gtctagcatg
    36481 atatctcctg tcgtcgcatc cagtaaacct gcaataatgt ttaggatagt tgatttcccc
    36541 gaaccagatg cacctagaag ggtgtagaat ttcccttctt ccaactcaaa gttgatgtct
    36601 ttgagaacct tggtgttgct gtcttcaaaa actttagaga cgtttttgaa ttcgataatt
    36661 ggttttttca attggcataa attccttctt tttcatagat taaccgatcg gggctctgtc
    36721 aggtccccac tacctcttgc agggagtaaa accacctgca tacatcttcg ctaccgatag
    36781 gctttcaccc aagatccgga cttctctttc aagcgtaata cctgagtgtt ccttgacttt
    36841 ttcgataacc gattggatca agtcctcgta gtctttggcc gttccatctg cgacattgat
    36901 cataaatcct gcatgctttt ctgacacttc tacgccaccg atacgatagc ctttcaagcc
    36961 agcttctgaa attaactgac ctgcaaaatg cccgactgga cgcttaaaga ccgagccaca
    37021 agatgggtat tccaaaggtt gcttgagttc acgtaggtgc gtcaagcggt ccatttcctg
    37081 cttgataacc tgatgggttc ctggagctag ggcaaattta actgacaaga caactgcacc
    37141 agactcctga atagctgaat ggcggtaacc aaaagccaag tctttagcag acagggtttc
    37201 gatttctcca tccttggtca agaccttaca agactgcaag atgtgagcaa tctcgccacc
    37261 ataggcaccc gcattcataa agacagcacc gccaacgctt cctggaatac cacaagcaaa
    37321 ctcaaagcca gttaaactat gacggagggc aatgcgagtt gtttcaatca agttagcccc
    37381 agcttctgct tcaatggtat agccatcaac agaaacgtta ttgagcttgt cacacaagat
    37441 gacaaatcca cgaatcccac catcacgaac gatgatattg cttgcattgc caagaaccat
    37501 ccaagggata ttttcttggt tggcaaattt cacaaggcga gccaactcaa aacgatttcg
    37561 tggaaagacc aaataatcag cctctccacc tacttttgta taactatagc tatgcaaggg
    37621 ttcctgaaaa cggatatcaa ttccttctaa gatttcaagc attttttctc ttacagacat
    37681 gtcactcttc cttttccaaa attcattcca ttataccatt tttagagaca tttgacgacc
    37741 ataaaaatac cttgtttgga ttttgcataa gaaaaagagg ttcccccctt tttatgattt
    37801 tttacaaaag atttccttgg ttccataggc gaccagaacg agctccagtg ctagaatcac
    37861 ttcaaccaag actggatttg tcaaccagcc tacttggaaa agagatggtg ccagatcaaa
    37921 gaaggcatgc aagccatagg ctgttaggag ataaatccat ttcttctggc gaacagcttg
    37981 gtaaacccaa actgtcaaaa gtaattggaa accaagcgcc aagattcgct caaaaccaag
    38041 caaataaatc tgccagaccg aaagtgactg aatggttttt aacatatttt cagacagtaa
    38101 ttgcataacc tgtggattct gagtttgaac tgccgaaaga acaatgtaaa gattgagtaa
    38161 actagtaagg cctagaaaaa tcaactccaa gccaccatgc cccagtccat aggccaaggc
    38221 gtctgccttt tccaaacttc tctttttctc aaaccatttg aagaaaacaa gacgagccgt
    38281 ttcctcaaaa aatgctgcca tggctaggcc atagataata tagataagcg gatgatcttg
    38341 caagagggca atactaccgt ctttttgagg gtgcaaaatc aagatatgca ccagtttttc
    38401 caaaatctgc gaagagacaa agaaagcgac tgcacccaag cccaagacag ctagattaat
    38461 ctggtatttc tttttggcaa accaaatgct tcctatcaga aaagctagca acagcaacat
    38521 ggtaataatg atatgaatgg tcattttctt ctcctattct gccttttcaa tatctttttt
    38581 catctcgtca acattgaact tagcaaacaa gtattgacgg tcttggactg ggaaacgttg
    38641 gtccaactgg tcaactgctc ccacctcgat aatgccttcc ttgatgacaa aatccatgac
    38701 atgtccaccg aaggtcaaat catctgatat gaagtgcaga tggtagcctg ccacactgac
    38761 cccatggaaa atctcaggcg tccagaaacc aacaatagtc cccgcaacat tgtcacgact
    38821 atattccggt tgatgggttg cgacatcagc aaacttggta tcgggtgttg acttaggaat
    38881 catacgcaca tgcatatgta aaaattcccc ccgaatcttg atagagcgga aaagattttc
    38941 cccatcataa taagactcaa ttcgttcttt caattccttg tctgtcatct caaagcgctg
    39001 gcggaaaatg acctctgcct gatgcggtac cactgcagcg taaggaataa gggcatctgg
    39061 tgacacttcc acaatttctg gctggtctcc tgaccctttg gcctgataag ccttgccatc
    39121 caagacaatc aattccccat caatggaatc caaggttccc aaaccaaggt caccatgttc
    39181 tagcaattct cctactgtca tagtaccacc ataaaggcca gccatcaagg ctccaagagt
    39241 attgtattga aataatttca ctggttcctg cacgttctta tccattcact ttcttgtctg
    39301 ttattctata aatcttactc ctaagtatac cacatttgcc cctagatgtg aacgagagaa
    39361 acgttctaga cattgccaag aaggaaaaaa aagggtacaa tgtaacaaaa tcaagggagg
    39421 tctggaatga agaaacaaag caagtacaaa gaggtcgttt cctatctgaa aaatggtatc
    39481 gagtctggac gatttccgac gggtagtcgc ctgccttcta tccgtcaact gagccttgac
    39541 tttcactgca gcaaggacac cattcaacga gccctgctgg aattacggca cgaacaatac
    39601 ctctatgcca agcctcagag tggctactat gtattagaac aagggcaaca tcaagaccta
    39661 gaaatcgagg ttaccgacga acatgccagt gcctatgacg atttccgact ctgtgtcaat
    39721 gaaaccttga ttggccgaga aaactacctc ttcaactact atgacaatca agaaggatta
    39781 gaagacctaa gacagtccat tcacaaactc ctctttgagc aagctctcta ctgcaaggct
    39841 aaccaactag tactgacttc tggaacccaa caagccttat ttatcctctc tcaaatatcc
    39901 tttcctagac aagccaagga aatcttggtg gaacagccaa cctaccatcg gatgaatcgc
    39961 ctcttgattg cacaggggct ggactatcaa acgattgaac gaggcattga tgggattgac
    40021 ttggaggagc tggaaggcca cttcaaaaca ggaaaaatta aatttttcta caccattccc
    40081 cgatttcact atcctctggg acattcctat tctgagcaag acaaacgatc tattcttaac
    40141 ttagctgcca agtatgatgt ctatatcgta gaggacgatt atctgggtga tttggactcc
    40201 aagaagggcc aaaccttcca ctatcttgat acagaggagc atgtcattta tatcaagtcc
    40261 ttctcgacca gcctttttcc tgcccttcgt attacagcac tcattcttcc aaatgctatc
    40321 aaagaagcat ttgtggccta caaaaatatc ctagactacg acagcaacct cattatgcaa
    40381 aaggccctgt cactctatat tgacagtcaa ttgtttgaaa aaaatcgttt ggctcgcttg
    40441 accaatcatg aatcttacca aaaacaaatc gaggaaagga taactaaaac accttgtccc
    40501 cttcctcatt atcccctaca cgatggttta ttgctagacc tgagacagta tcctaaaatc
    40561 gccagtctca aacacagtca actgggcttg gacttctttg aagaggccta tttgagcacc
    40621 tgtccttatc aatttgccaa ggtgtcccta gacaatctgg aaaatgtttt aaactattta
    40681 aaagcagaat tggaatgaca tccaactctg ctttttctta ttcttcaact tcagttagac
    40741 ttgctgcttt ttcaagatag ctttggtaag ttccttcatc cttaagtttt tggatgacct
    40801 tgtctaccac ttctttcaaa tcatcactat tttttctaag agcaacggca ttggcgtcgc
    40861 cgtccttcat cttcaagctg acagttgcga cagctaagcc agcgttttta gcagcataac
    40921 taagtgcaac aggctcatcc atatgaacag catctatttt tccagcctgc aattcattga
    40981 ctgcttcacc catattagtt agggaagtta attgagcttt tggcaattgt tccttgacca
    41041 ttgattctgg aacagtccct ttttgggctg caatattagc actttctagg ctagttaaat
    41101 ccttgtattt ttccacatca gccttacgaa ccaagaaact aatcttgttt tcatagtatg
    41161 ggattgaaaa atcaaagact tcttttctct cgtcagtagc actaattcct gcaactgcta
    41221 ggtcagcctt accagtttga agactggtca aaacattgtc aaaactcatg cttaagattt
    41281 ccaacttaac cccaagttca tcagcgatag cctgagccat gtcgatgtct gcaccgacta
    41341 cctggttctt tccatcaacc aatgattgaa attcaaaggg tgcatagtca ggactggttg
    41401 ccacaactaa tttccccttt tgcttaatgg cctcaacagc tgactgagaa ccattagaac
    41461 ctgactggca agctactaag aagaaacttg caagaaaatt acataaaaca aatatccatt
    41521 tttttgattt cataaataaa caacctttct gttaattttg tataattata acgatatcca
    41581 agttacttgt caagtgtttt ttaaattttt atctcaaaaa tattttttcg ttcaaaaaaa
    41641 ggagccatca gttgatttca agctcctttt tatacagaat taaactattt tatagttcga
    41701 caatcttacc tgtttcaaag tagacaaccc attcacagat atttttagca tagtcaccga
    41761 tacgctccaa gtaggaaata acttggaaat aatcacgacc cgtaacaatg gcttctggat
    41821 ttttcttaat ctcttcagtc gcaaggtcac ggatagtttc aaaatagtgg ttaatttgct
    41881 catccatgga ggccacccgg tatgcgtcgt caacagaacc attaagataa agatcaagtg
    41941 ctgcttccac aacgctttta acttcacgtc ccattttttt aatttcttcc tctacagctg
    42001 ggatgcgttc ttcccccttc atacggatgg ttgcctgggc aatggctaca gcgtgatccc
    42061 ccatacgctc cacatctgat acagccttaa ggacagtcaa gactgtacgc aaatcttgag
    42121 agactggttg ttggagtgcg atcatttcaa atgatttctt ttccagtttc acttcgtatt
    42181 catttacttc tgcatcatct tcgatgacct cttttgccag gtcacggtca tgcgtgacaa
    42241 aagcacgtac cgtacgattg atttgtgaga gcacttcttg tcccatagcg tagaactggt
    42301 tatgtaattt ctctaaatct tcttcaaatt gagatcgtaa catctttcat ctccttatcc
    42361 aaattttcct gtaatatagt cttccgtttc cttgtgttgg ggatcaagga acatctgctt
    42421 ggtatcatta aattcaatca aatctccatc taggaaaaat cctgtcttat cagagatacg
    42481 tgaagcttgc tgcatggaac gggttaccag aagcatggtg tacttgtctt ttagaccata
    42541 caaggtttcc tcaattttac cagctgaaat cggatccaaa gccgaagttg gctcatccaa
    42601 gaggatgatt ttaggactag ttgccaagac acgggccacg cagacacgct gctgttgacc
    42661 acctgacaat ccaatagctg aatcatatag acgatccttg acctcatccc agatagaggc
    42721 accttgcaag gctttttcta cggcttcatc cagaacctgc ttatccttaa ttccattgat
    42781 acgaagcccg tagacaacat tctcatagat agtcataggg aaaggattag gttgttggaa
    42841 aaccattccg atttccttac gtaattcaac cgtatctgta cgcggactgt agatgttgtg
    42901 accattgtac accacggatc cagttgtggt cacctctgga ttgagatctc ccatgcggtt
    42961 gagagacttg aggagggttg acttccctga tccagatgga ccaatcaagg ctgtaatttc
    43021 cttaggttgg aaagataggg aaacactatt caaagccttc tttttattat aatatacgga
    43081 caggtctgat acctgtaaaa tcgcatctgt catacggttt cctttctaac caaagtgacc
    43141 agatacatag tcattggtgg actgtagctt ggcattttgg aaaatagttg cagtcttgtc
    43201 atactcaatc aaatcaccca agtaaaagaa gcctgtatag tcacttgcac gagcagcctg
    43261 ctgcatatta tgcgttacaa tgatgatggt aaagtttttc ttgagctcaa acatggtctc
    43321 ttctagttgc atggtcgcaa tcggatccaa ggctgaggct ggctcatcca ttaagaggat
    43381 atctggctta acagagatgg cacgagcgat acagagacgt tgttgctgac cacctgataa
    43441 ggtcaaggct gacttgtgga gatcgtcttt aacctgatcc cagagggcag cctgacgaag
    43501 ggaggtttct acgatttcat ctaggacttg cttatcctta actccagcac gttcatgcgc
    43561 aaaggtaata ttacggtaaa ttgacttagc aaatggattg gggcgttgaa aaaccattcc
    43621 aatgtgttta cgcatttcat aaacgttgat ttctggacgg ttgacatcaa ttccacgata
    43681 gagaatctgc ccagttactt tagcaatatc aatagtatca ttcatgcgat tgagactgcg
    43741 taagtaggta gatttccccg atcccgacgg accaatcaaa gctgtaattt tatttctttc
    43801 aaattgcata tcaatcccct taatggattc atttttacca tagtaaacat ggacatcctt
    43861 agtagaaagg gctacttttt cttcaggaaa ggtaaggata tgcttctcat cccagttata
    43921 tgttgacatg gcttctcctt taggcagcgg ttaatttctt gtgtagatag cttccgaact
    43981 tacgagctcc aaagttaaaa atcaggataa agatcaggag cacagcggca gaacctgctg
    44041 atacaatggt tccatctgga atagtgcctt cactattgac tttccagata tggacagcca
    44101 aggtttctgc ttgacggaag atagagatgg ggctagtcac actgaggata ttccagttag
    44161 accagtcaag agctggcgcc gattgccctg ctgtatagat cagagctgca gcttcgccaa
    44221 agatacgacc agatgccaag acgacacccg ttacaatacc tggaagcgct tctggaataa
    44281 caacatgaac cactgtctcc cagcgagaaa tcccaagagc cagaccagcc tcacgttggg
    44341 tatggtgaac gtgtttcaaa ctatcctcta cattacgcgt catctgaggc aagttaaaga
    44401 ctgtcaaggc caaggcacct gaaatgattg aaaatccata ctcaaactgg actacaaaga
    44461 tcaagtaacc aaagagaccc accaccactg atggtaaaga ggacaagatt tcaatacaag
    44521 tccgcacaaa gttggtaaca ggaccttttt tagcatattc agccaagtaa atcccagctc
    44581 ccatagaaag aggtacagaa ataatcaagg taatgaccaa taggaaaaag gaattgtaaa
    44641 gctgaatgcc aatcccacca cctgcttgaa aagcagaaga ccttccagtc aagaaagacc
    44701 aagagatatg gggcaagccc cgaaccaaga tatagagaat caaggaagcc aagattgtca
    44761 caatgatgct agcaatcgta tagaggacag ctgttgcaag tttatctaat ttcttagcgc
    44821 gcataatttt tctttcctct ttctttcgta atcaatttaa tcacactgtt aaaaactaaa
    44881 ctcatcaaga gcagtaccaa ggccagtgac cagagaacat tattatttac agttcccatg
    44941 acagtgttcc caattcccat agttaatata gaagttaaag ttgcagctgg tgtggtcaag
    45001 gaagttggga taacagctga gtttccgaca accatctgga tagctaaagc ctcaccaaag
    45061 gcacgcgcca tcccaaagac cactgcagtg aaaataccag aacgggccgc cttcaagatc
    45121 acacgccaga tagtctgcca gcgagtggct cccatagcga aacttgcctc acgataataa
    45181 cgaggaaccg cacgcaagct atccgttgtc ataaaggtta cggtcggcaa aatcatgaca
    45241 aagaggacgg aaatccctga caaaatccca aaaccagtcc caccaaagac actgcgaaca
    45301 aagggaacga cgacttgcaa gccaataaat ccgtacacta ctgaaggaat cccaaccagg
    45361 agttcaatag ctggttgcaa aatcttcgcc ccttttggtg atacttcggt cataaaaact
    45421 gctgcaccaa tagcaaaggg tgttgcgata agggctgaga gaatggtaac gataaaggaa
    45481 cccaaaatca taggaagggc accaaattct ttactagaag gattccaagt tcctcccaaa
    45541 agaaagtcaa agatattcac accattgaca aagaaggtcg acaagccttt ttgcgctacg
    45601 aaaaccaaaa tcatggccac aaggatgact atcaaagaaa gacaggcaaa ggtcaaacct
    45661 tttcctaatt tctccagacg agaattcttt gatggaagca acattttctt agctaattct
    45721 tcttgattca ttattgtctc ccttccaaca ctgtcacagt tccggcagca tctttttcaa
    45781 ccttcatttc cttaatcgga atatacttca atcctttgac aatcccttct tgggtctcat
    45841 ccgagagaac aaaattgaga aattctgcag ctaactcatt gggctgcccc aatgtataca
    45901 tatgctcata agaccacaag ggccaattat tgctacttat attttctgga cttaagtcat
    45961 agccattcaa cttcatgctt ttgaccgaat catctatata ggtaagagat aaataagaga
    46021 tagctcctgg actttttgat acgattgatt ttaccgctcc atttgaatcc tgctcctgac
    46081 tttgcatggc agactgacct tccataatga cagtatcaaa ggtagcacga gagccagagc
    46141 cggctgcccg attgataaca gagatgggta agtccttacc accaacctct ttccaattgg
    46201 ttacctcacc tatgaagatt tgacgaagtt gctctgtcgt taggttatca acatcaacct
    46261 ccttattgac aatcagagcc aagccagcta ccgcgacctt gtggtcaaca agagcagaag
    46321 catcaattcc gtctttttcc tcagcaaata catctgagtt tcctatatca actgccccag
    46381 actgaacctg ggacaagcct gtaccagaac ctcccccttg gacattgacc gtttttccaa
    46441 catggatcgt gccaaattca tctgccgcta cttcaaccaa gggttgcaag gcagttgagc
    46501 caacagccgt tatggattct ccacgatcaa tccagctagc acagcctact aaacaagccg
    46561 tcagccaaaa agcgataaga gacagagcaa gcttttttct ttttttcact gtttttctcc
    46621 tcgaaaataa ttatgaatac tgtgaatttt ttaagtagtt ctttatgagt tgacgcatga
    46681 attcttacca aatttctgcg caattgatta tttatataat ataggctata ttactctttc
    46741 ctaacctcct tttttcatat gtggataaaa tctcttgtct atcccttccc ccattgtcac
    46801 ccattatagt catttcgtgt ctctttttcc cctttttaat gcaagggaaa ttactctcct
    46861 tagatgataa tccaaaagct agaaaggtat ctcaaatctc tctactctcc cagactagtt
    46921 tacaactaaa aggaaaagat tctattttat gagaaatcta gtttacaagc ggtaagaacg
    46981 ctaataacta aacttcttgt actctttgaa aatctcttca aagcagtgtt ttgagctatc
    47041 tatggctagc ttcctagttt gctctttgat tttcatcgag tagtaaaact acatgtgatg
    47101 gcaatcaaga tatcaagaat catcctacta aaaaaatcca tactttcact ataacataga
    47161 ataagatatt tgactagcat tttcatttga atctgaggcc ttttggaaaa taatttttca
    47221 aaacatttcc agtaaccttt gcaaagccca agccattgcc tttaaccaaa acttggtacc
    47281 aaccatttgg cagactttct gccagctgaa cggtttctcc agccgcatac ttgacaaact
    47341 cttcttggcc aatttcaacc gactgttcga cctgactcgg tttcaaggct aaaccaagag
    47401 cgaaactggg ctcaaagcgt ttcttcttaa aagtacccag atgcagtcca ttgcgagcaa
    47461 tcttgagctt ccctaaatct ggcaaaagtt ctggcaagag ataaagctgg tctccaaaaa
    47521 tctgcaagat acccggtaga ttgaccttca aatggttttg ggcaaattcc tgccacaagg
    47581 caacttgttc acggctgagg ttactcttac ttgccttaaa tttaggagct ggattgttac
    47641 ccttaaactg tagatgggca acaaactgac cctctccctt aaactgatga gggtacatcc
    47701 gagccgtttc tggcaggtca ataccagcta ccattccatt gatatgctct actggcaaca
    47761 agtcaaaatc atactcttcc agcaaccaat tgacaatctc ttcgttttcc tcgggtgccc
    47821 aggtacaggt cgaataaacc agacgaccac cttcagctaa catggtcact gcatcctcca
    47881 gaatttctct ttgcaagcta gcacattgac tcggataatc taagctccaa tagtccatag
    47941 catcaggttg cttacgaaac attccttcac cagagcaagg ggcatcaaga acgattaagt
    48001 caaaatagcc tttaaagacc ttgaccaagc ggtcggcaga ttcattggtc accacgacat
    48061 ttgtcgctcc aaaacgctcc atgttttcaa ccaaaatctt agcccgtttg cttgaaattt
    48121 cattggaaac aagtagcccc tcccctgcta gataggctgc cagttgagtt gatttgcccc
    48181 ccggtgcagc agccaagtcc aagaccttca taccaggact gggttgggct acttgagcca
    48241 ccatttgagc agcaggttct tgcgaataaa ctaaacctgt agcatgctca ggcgatttcc
    48301 ctgaaacctt cccatagtgg ccccaagggg tttgagtaat ggcatcagaa aaggaaagtt
    48361 gctcttcttt taagggattg acccgaaagg ccgaaaccgc ttcctcctca aaagaggcaa
    48421 gaaaatctct tgcctcatct cctagtattt ctttatattt ttcaacaaat ccttctggaa
    48481 atttcattta agttcttttc ctttcgtaaa tataggactg aatttcctcc tgcatctcaa
    48541 gaggcaccat catgaccggc tgtctggttt gaaaatcagg agcttcacca aaaagggtca
    48601 caacccgata gcccagactt tcccctaaaa tactagctgc ggcataatcc catggttgca
    48661 gataggtgag ataggtcaac aaacgccctg acaaaatctt ggcaaaacta atggccgcac
    48721 ttccatagac acgaacacca agaaccgctc ggctcaaatc agccagcccc cattcattgg
    48781 tttccagcat accactattc cctgcaatga gaaaatctcc aagtggttta gttttaaaag
    48841 aagctagggg cctatcattt agacaaactg gaaattcccc accaccgtgg taacaatccc
    48901 ctttgaccac atcataaatc agaccaaact gtccctgacc attttcaaaa taagccatca
    48961 taacagcaaa atcttcctgc tgggctacaa aattattggt accatcaatg ggatcaatga
    49021 cccaaacctt gccctcttga accgaggctc gcagacaacc ttcttcagca caaatcttat
    49081 cctcaggata acgggacaaa atctcaccaa ccaagagttc ctgaacttct ttgtccagtc
    49141 tggtcaccaa atctgttgga gaggacttgg tttcaacacg caagtcttcc tgcatatggt
    49201 caagaatgta ctgacctgct ttcttaacaa gctctttagc aaattcaaat ttacttttca
    49261 agagaaatct ttcctttccc tttttctttg gcagcctgaa ctgctcggta aagtgaatag
    49321 ccactaaccg tttcaaattc tcgtcccaaa cgtttctctt cgctcttgct tggcacgacc
    49381 gctttgaatc ccttatagga gtccagtaac tttttagcct ctactttgcc ttcataggca
    49441 gcttcaacat cattaaaaaa agaaagcact gaagcaagtt cttcagtgct ccacgacaaa
    49501 tctagtgggt aactatactg tttgttcatt aactaatacc agctctcatt cttgcttctt
    49561 ttagttcttg cttacgataa ctacgaggga gaaaagcacg aatctcatct tcattaaaac
    49621 cgatttgcat acgcttggca tcaataataa ttggacgacg caaaagacta ggatactgct
    49681 caatcaaatg aagcaattcc gataccgaaa tactctctac atcaatattc aatttttgaa
    49741 aaatttttga acgagttgaa atgatgtcat cagtaccatt ttcggtcaag gaaaggatgt
    49801 gttgcaattc ttttcttgtt aaaggactgg tcataatatt gtgttccaca aagggaacct
    49861 tatgtttttc taaccaggtc ttagccttac gacatgatgt acagctcggt gatagaaata
    49921 gtgtaatcat gcttttctct tcttatctat actttgctac ttctattata caaaaaaata
    49981 aggcgcttga ctagggattt ttagaaaaaa agcctatttt ttcaggaaaa ataggctgtt
    50041 tgcgaacgat tgacacaatt ggatttggtt aattcactct taacgatggt tttaaacgat
    50101 atatatattt atatatgtaa attaaaaaca tctttccttt cacttcctac gacttttcag
    50161 acacagatag ccaaagaagc tttcatagag ggcaaaaaag aggaggaagg catgaagaaa
    50221 gaaggtctct ggcaaaatca taataacagg atccttggct ggatcaaaaa gccaggtatc
    50281 atctcccaca aagagaattt gatggaaaag agtaaagaat tggtcaaaac caatcaaaac
    50341 tcccccaagt ccaatcatca caggtaagac tactagagcc aggagacttt ttcgataaag
    50401 agacaaaaag tcctttttca caatcctatt gacaaagaca tagaaacttg gcagtgtcac
    50461 tagagctact agctgaacca aatgaaagag attcttgacc actgcgaaat ggtgcaaacc
    50521 agctgctgac gaacgaaaat caggcatctg taagacctga ctaaaaggat tggtcagata
    50581 attcatcaag atatgaaaat tgtattgaat ggtttctggt tttagataga ctcgattcgt
    50641 taagtttagc cactgaatct ccataggata gaaaatccaa gccagataaa tggtcagaag
    50701 gattgagagg gagaggagaa agagcataga gccccaaaag gtcaatttag ttttcatcaa
    50761 aatcccactc cgcaaggcta gaaaccacat gtgtcggtgc gattggcagg ccagctactt
    50821 cttctgcctt ggtaaaacct gtcgtcacca agagcgttgg aatgccattg tcaatcccag
    50881 cccggatatc agtcaaataa ttgtccccaa ccatgattaa ctcttcacgt tccaaaccta
    50941 agtgctcaac tgccttgtcc ataatgatgg cattgggttt tccgatataa accggcttca
    51001 ctcgtgtcgc tacttcaagc agcgtaatca gtgagccagc acctggcaaa agaccacgtt
    51061 ccgtcgggat gttgaggtca ggattggttc cgataaaatg ggcacccttt tgaatagcaa
    51121 gagttgctgt ggcaaatttt tcatagtcga cttgccaatc cagaccaact accacgtagg
    51181 caggtttttc cttgtcttcc acataaccag ccgccttgat ggcttccttg agtcctgctt
    51241 ctccgacaac atagacggtc ttttcaagcc ccaaatcatt catatagtcg atggttgcca
    51301 aagtcgctgt gtagacagtc gataggggcg tatcgatatt aaaattctga gccaacatct
    51361 ccttaacact ctctggagtg cgggttgtat tgttggttac aaagagatag ggaatgtccc
    51421 gcttttgcaa ttcatgaaca aaagtctctc cagcagggat ttggtctttc cccttataaa
    51481 tggttccgtc taaatcaatt aaatagcctt tatatttcat ctatttctcc ctaagccttt
    51541 tttatttctt gccaagtaat gattgcttgg gcattgataa ccccatcact tgtaatttca
    51601 tgcttgcttt ccagtccagt ccgttcaaca gccgatgtaa tcaccccacc tggtcgaact
    51661 tccttgacat acttgaggtt gattttcttg ggaatatagt gggtcaaaaa atccgctccc
    51721 atgacctcaa aaatccagtc taagtattta ctgttattga catgaccatt catatccaag
    51781 tcgtaaaaac gaacatggta atccttgctg atcgactctt ccaaggactc atacttcggt
    51841 ccacggataa gttttttatc aaaatcagac tggtaaggag ccacaatctc aggttcaaca
    51901 gcatggactt ttcgactgtc gcggtccatg agaacaaagg tcgccatcat atggatgagc
    51961 tcctgccccg cttcattata aatagtaaag cgacggtagc aaaaaagtcg attgtagctc
    52021 aaggcttccg tttcgatggt aatttcttcc gcaaaacgag gcaaacgaac cacctcaata
    52081 tcatattcta cgataatcca gaccagatta tagtcttcca aaatggcctt atcactaact
    52141 cccagttcaa tcgactgcat ccctgaaact tgcagtgaca gcaaaattac atctggaagt
    52201 ttgatatgac cgttcatatc agccatatca aaaggaattt tcattttcat ttgataagtt
    52261 aagcccatga tcctactcca aaataaatcg ttccgctaca gtatctccca aaaagagacc
    52321 tctctttgtc atgcgaacgt ggtcaccctc aatctgcatg aggccttgtt gaaccaaatc
    52381 tctgacaatt tctccataaa gtccagcaaa agactgtcca aatttttcct caaatcgcgc
    52441 catggaaacc ccggatttct tgcggagtcc caagaacatt tcttcttcca tttgctcctt
    52501 ttgactcagg tgatcttctg taatacaagc attgccttcc tcaaccgcac tgagataatg
    52561 acgaatggga ccatgatttt tatagcgtac tccattgaca taaccagatg cccctgcacc
    52621 aataccatag tattcagcat tgtcccagta catgagattg tgacgacttt caaagccggg
    52681 tttggagaaa ttagaaatct cataatgctc aaaacccgct cgctccagct ctgcaatgat
    52741 gtactcaaac atctccgctt ctagttcctc cttaggcaga ggcaatttcc cacgtcgcat
    52801 ccgattcata aagaccgtat ggttttctaa aatcaaacta tacaaactca tgtggggaat
    52861 atccagtcca atggctttag ccacattttc ctttacttgc tccatggtct gaccaggcag
    52921 agcataaatc aaatcaatgg agatgttgtc aaaaccagcc agtttcaggc gatcgatatt
    52981 ttcataaata tccttctcca aatgactgcg cccaatcttt ttcaacatct tatcatcaaa
    53041 ggtctggaca cctagcgaaa cacgattgac agccgaattt ttcaaaacag ctatcttatc
    53101 cgcatccaaa tcgcctggat tggcttcaat ggtcaactct tctaagacag acaagtccaa
    53161 gtttttagtc aagccattca gtaaaacctc cagttgcgga gccgacaggg ctgtcggtgt
    53221 tccaccaccg atataaaggg ttgacaactt ttcaatatca taagaacgaa actcttccag
    53281 cagatgctct aaatagctgt cgactggctg atttttgatg aagacctttg aaaaatcaca
    53341 ataataacaa atctgggtac aaaatgggat gtgcacatag gctgacgttg gttttttctg
    53401 catagtaatt attataccac aaagactaga ttccagataa aaatcaccat ccccagatac
    53461 atagtccgtc cggagatggt gatggtttat tcttctgtta tatcaatcac aatctcttct
    53521 gagtcatcaa gagcttcggc tttttcttgc cattgctcct tgagattatt taattgattt
    53581 tttgatgctt ctgtcgcttg aaaagcatag gatttagctt gagcaagtat actgtccaca
    53641 gtgatttcac ctgactcaac ctgttctttt gttttcagaa caaaatctgt agcctgctcc
    53701 ttaacttctg tcagtttttc acagacttgc tccttggcat actccggatc ttctctcaaa
    53761 tcatctagaa aatcttgagc ctgactgcaa acttgtttgc ccttatcact tgttaaaaac
    53821 aaggcaagag ctgcacctga aacggttcct aaaaggattg aggataattt acccataagg
    53881 attctccttt tttatttttt gaaaaattta cttgcaagac gaagagctga cagacttgca
    53941 ccagtcttga gtgtttttga accagctgat gaagctttct tgctcaagac acgcgcatgg
    54001 tcattgaggt ctgaaacaga tagagataaa tctgcaacag cactgaagag tggatcaatc
    54061 gtagccacct tgacattgat atcatctgcc aagacattga ccttagccaa caactcattg
    54121 gtgtgatgca aggtcacatc cacatctgaa gtcaaggttt taatcgtctt ttctgtttca
    54181 tcgatgacac gaccaagctt ttgtacagta atgatcagat agaccaaaaa gacaatcaaa
    54241 gctagggcaa caagaatata tgcaacttct aacatttagt tttcctcctc tgtaatatag
    54301 taaggggcct tctttcgatt ttgataaata acgatcatta taccgagacc gataaggaca
    54361 actgacagcc attgggacac tcgaaggccg aagaacatga gactatctgt tcgcatacct
    54421 tcgatgacca tacgaccgaa accataccaa atcaagtaaa aggccgtgat atgacctcgt
    54481 ctgagactct tccatttccg tctaaaaatc agaatcaagg caaagccaag cagattccat
    54541 agagactcat aaaggaaagt cggttgacgg tagctcccct caatatacat ctggtcacgg
    54601 ataaagccag gtagataatc cagattatcc actgttgcac cataagcttc ttggttaaag
    54661 aaattacccc aacgccccaa actttgagca atcataacgc taggcgccgc aatatctaga
    54721 aaatcccaag tattgatgag tttacggtca gcaaagatat agagcacaag agccccagtt
    54781 atcaaaccac cgtaaatggc caaaccacca ttccaaatgg caaaaatctc tcctaaattc
    54841 tgactatagt aatcaaatcg gaaaataaca tagtagagac gagctcctaa aatagccaag
    54901 ggaaaggcta ctaagataaa atctaaaata tcgtctggta tgatcttctt tctaggtgct
    54961 tctttcatgg tcaaataaac cgcaagaatc aagcctgtca caatacataa ggcataccaa
    55021 cgaatggcta ggggtcctag ttgaatagca attggatcaa gcattttgca cctcatttcg
    55081 agcgatgaga cttgtcagtc gttcgtcgaa caaacgggtc gcatcaaagc ccatttcctt
    55141 ggcacgataa ttcatggcag ctgcctcaat cacaacagag atattacgac ctgttttaac
    55201 tggaatacga atacgaggaa tggctacgcc agaaacttca agttcctctg cattgtttcc
    55261 aagacgatca aaggtcttat gcgtatcgta attttccaaa tagacagcaa gctgaacctg
    55321 tgaagaatcc ttgacagcac tcgcaccgta gagactcata acatcgataa taccaacccc
    55381 acgaatttca atcaagtgtt tcaaaatttc agctggttca ccccagagag taatctcatc
    55441 cttggcaaag atatcgacac ggtcatctgc taccaaacgg tgaccacgtt tgacaagctc
    55501 aagacctgtc tcgctcttac caattccact atctccctga atcaagacgc ccatcccata
    55561 aatatccatc aagacaccgt gcacactggt acgttctgcc aaacgagaat ccagatagct
    55621 agataactct ccagataaac gactggtagc tgcacggctg gttaaaatag caatcttaca
    55681 ttctctagca gcctttaaca tctcctctgg aaccaccaaa ccacgggcaa caatgactgc
    55741 tggtgtctca gatagaaaca tttttttcaa aacttcataa cggctgttgg aaggcatgct
    55801 gatcagataa gaccactcct tcatccccaa aagttgaatc cgctctggtg tgtagtagtc
    55861 aaaatagcct gtcatttcaa gaccaggtcg cgtaatatcc gctgtattga tttccttttc
    55921 aagcaactct ggttcaccat agacaatatc tagtctaagc ttttcaatca cttcttttac
    55981 taaaaccgac atcatttcct ccttcaaatg agttcttctc tctattatat caaattgtag
    56041 gaggaagttt cagatttttg caggctttgg agtatttatt taaaagaaaa aggactagat
    56101 ttctctagcc tttcattcca attagaattt tttacgttta cgagctactt ctgatttacg
    56161 tttacgtttt acagaaggtt tttcatagaa ttcacgtttg cgtgtttctt gaagagtacc
    56221 agctttagta accgcacgtt tgaaacggcg aagtgcgtcg tcaagagatt cattcttacg
    56281 tactactgtt ttagacattt ttttcactcc cttcaagttc gatatctatt tcattctaca
    56341 cgtaaaagga ataattgtca agcaaaaatg ctgtttaatt ttgatttttt cttccattta
    56401 tacaagagtt gaaagcgttc aatagaacat tgctttttta tttttcgagt aagctaagcg
    56461 cttcagcatc tgcgatgatg gttacatcag ggtgattttg gaggctactt gcaggtaggt
    56521 tctcagtcac tgggccagat actgttccgg caatggcttc tgctttcgac tcaccgtaag
    56581 caaaaagaat aatagacttg gcatccaaaa tgtttttaat ccccattgaa atagcttggg
    56641 ttgggacgtc ttcaatcttg gcaaagaagc gtgcattggc ttcgatagta gactggtcaa
    56701 gttctactag atgcgtttga ctgtcaaatg gagtaccagg ctcattaaag ccgatatgcc
    56761 cattgcgacc gattcccaag atttggaggt caactggatg gtcagccaaa atttggttgt
    56821 agcgttcaac ttcagcttca gcattgtcct taacaccacg aggcaagaaa ctttctttaa
    56881 atggtttttg gttgaacaag ttttcttgca tgaagtaacg ataagactgt ggattgtccc
    56941 catcaaggcc cacatactca tcaaggttga cactggttag atttgaaaaa tcaaggtcac
    57001 tctcaacaat ttccttgtaa aattcaagtg ggctacttcc tgtcgcaagt cctagagttt
    57061 gagctccatt agccaatttt tccttcaaaa tctcaaaagc aacttttcca ccttgaactt
    57121 ggttttcaac tttaataact ttcatctttt catcctccat ttctgtctat atttattata
    57181 tggtatagac caatttttgt caagtgaaaa cgatttaatt tctaaaaaaa gagcgtccaa
    57241 acttgaaacg tgttataatg gataggatta gaacttagaa agaatgaaca gatatatgaa
    57301 tacagctgat tttgatttcc acttgccaga ggaattgatt gcccaaacgc cccttgaaaa
    57361 acgtgatgcc tccaaactcc tcatcgtcaa ccgtgagaca ggagaaatgc aagataaaca
    57421 cttccactct attattaata tgctggaacc tggtgatgcc cttgtcatga acgacacccg
    57481 agttctccct gcccgcctct atggtcaaaa agtggagaca ggaggtcatg tggaacttct
    57541 cctccttaag aacactagtg gagacgagtg ggaagttctg gctaaacctg ccaaacgcct
    57601 caaggtcggt actcgtatca gctttggtga tggccgcctc agcgctgtcg ttacagaaga
    57661 attgacccac gggggacgca ttgtccgctt tgaataccaa ggaattttcc tagaagtctt
    57721 ggaaagtctg ggagaaatgc ctctgccacc ttatatccac gaaaaattag atgaccgtga
    57781 acgttatcaa accgtctacg ccaaggaaag cggctctgct gcagcaccga ctgctggtct
    57841 tcacttcacc aaagaactgc tggcagaaat ccaagctaag ggtgttcatc tagtctatct
    57901 gactctccat gtcggactcg gaacctttag acctgtttct gtggataatc tggacgaaca
    57961 cgaaatgcat tcagagttct atcaactttc tgaggaagct gctgccaccc ttcgctctgt
    58021 caaagaaaat ggtggtcgcg tcatcgctgt cggaaccact tctatccgca ccttggaaac
    58081 tattggttcc aagtttgatg ggcaaatcca agcagattct ggttggacca atatctttat
    58141 caaacctggg tatgagtgga aggtcgtgga tgccttctca accaacttcc atctgccaaa
    58201 atcaactctg gtcatgttgg tttctgcctt tgcaggccgt gaattagtct tagatgccta
    58261 ccaccatgcc atccaagaac actaccgctt cttcagtttt ggtgactcca tgtttattta
    58321 ttgagaaaga atttctctaa atcttctaat accaataaat cgctaagata ttatttcaaa
    58381 gaacatctac aattgaaact ctagctagct gtagaagacg cctagtacat tgaaattaaa
    58441 atgcttcccc ctagcttcga aaatattgcc atagattgcg ttgactctcc aaattgattc
    58501 atctatattt tatttcagct tcctatattt tcttcgctgt ttgtaaatca aaatgcaaga
    58561 cacatgagta gcaccatatt tgttactctt atctgtcctc tcaagagact attatgagtt
    58621 atttcagaat cattcactac tttgaccctg actctcctta gtctcaaaat caaagactta
    58681 tactcttcaa aaatctcttc aaactgcgtc aacgtcacct tggattatat atgtgactga
    58741 cttcgtcagt tctatctaca acctcaaagc agtactttga gcaacctgcg actagttttc
    58801 tagtttgctc tttgattttc attgagtatt aaacaaaaag tgaacaaatc tgaattctaa
    58861 tgtacagaag actaggcttg ttcacttttt tatagtcgct ataagatgac cttatctata
    58921 gctttttata tataattata tataattata tattcagaca tactattatc aattttgtcg
    58981 cagggaggaa tctgttaacg cacccattca ccattatcat tgactctata gccatctata
    59041 cttgtattga ccgctaactc acccgatgca tttacataat accatttacc accaacttgg
    59101 aaccattgat tgactttcat agaaccgttg ctgttgaggt agtaccatga accattaact
    59161 tgtacccaac ctgttgccat ggaaccatca gtattataaa aataccacat accattttct
    59221 tgtttccagt ctgttgttgg agcaactgct ttagctggtt ctactgctac atctgttcct
    59281 tggttagatg taacagatac aggatacgaa ggaatagatg attgctcagg aacaacaact
    59341 ttttcaggtt ctctcgtccc tctccttata cgtcttttta ccatctcttt agtaatttga
    59401 cgagaagtag tttcttcaat tgttccatca cgttcatcta cagtatagat tgtagtaaga
    59461 gtaatttacc aatttctcct acttcttcta cttcttgact tttatcaaga gttgggtcat
    59521 cgagatattc tgtttcgatt ggaatttctt ggacaagaac ttggggcttg gttccttttt
    59581 taacaactct tgtttgagag tcttcttttt gacttaaagt actctcagtt acttgtccac
    59641 tctttccatc tacatcataa gttatcgttg taactgtttt cccattcttt cctagagtaa
    59701 tctcttgctc ctgtcctgca gaaaggtcat tgtctgcttc atatttagta gcacatggaa
    59761 caagaacttc ttcaaccttg cttttagctg gaactttgat aactgtatcc gtggcttgtt
    59821 ttctatcaac agtaacctgt tcggtaacat gaccagtctc tggattaaca tcgtaggtcc
    59881 ttgtcgtagt tacatagcca tcctctccat caattgtaac aggattttca ctacggtctt
    59941 ttgtttcatc tttttcataa cgaattcgcg tacttgaaat tttcttggtt actaccttag
    60001 gtttagtcgc tacttttaca ataatacccc cattgtcagc gtcatcatac tctattccct
    60061 cttctttatc tctagtatca tctctgacat attgaatccc atcagcagca tgaacaaaac
    60121 ttgtattcag attcctccta aaaataaagt tagcccgatt accgcagaac caaaaatctt
    60181 tccgagttta cgtaatgcat agcgcttatt agtattagat tttgccatta catcctactt
    60241 ctagtatagc atcttttcta tcaaacgtta aacaatatac tttatatata aaatagactt
    60301 agaatgatat attgattatt gaactaacac tttaactata tcgtaatcaa tctcatatat
    60361 aaaggattgc agacatctta tctaaataca tgctaatata tttagataca aacattccaa
    60421 cttgataatt ttcactcatc tttcatcatt ccttatacaa ctatgcagta taaatagaat
    60481 agttttctca tcagaatgag actattttaa tattagataa tttgatagaa aaaacatgaa
    60541 taaaattggt tgaatttaat tccctaactc gatagaggat tctattttaa atttaacaac
    60601 agctaggatt acactataaa aagtacatta ccacctgttc ggctggagaa tctagtcgat
    60661 tagctccctc ttagttacaa gcttaaagcg attttttaac taatactaaa ccagattaaa
    60721 gaaggaacta gaacatctgt cttgtactaa tcaatatgct attttaaagt ttcaaataaa
    60781 cttggaatgc taattattat atttacaata aatagttgac ttcgatagaa acagaaaata
    60841 gaattcaaca ttcttcccta cttataccat aataaataag atccgcaaga tagccttttc
    60901 tctctacacc attaacaatg gtttgtagat aggacattcc agccttttcc atgacacgac
    60961 ctgaagctgg gttgagactg gcataacgtg ctctgacctt ttgaaaacct gcttgagtaa
    61021 aacaaaagtc caagatagct ttcaaagtct ctgtcatcat accatttccc cagtaagcct
    61081 tgcctaacac atagccaatt tcacagctta aatcagcctc gtctatctta acgatgctga
    61141 tatctcctat cacttgctct gggttttctt ttagacaaat ggcccattta taatagttga
    61201 gattagtata ggaagcaacc caattgcgaa tcgagtttcg agtgatttcg atatcaggat
    61261 ggggatccca ggtaacatag gtcagattct cagcagatga agcccaattt tgaaacatgg
    61321 cttctgcatc actctccaca aatcttctta aaatcaaacg ttctgtctgt aatatttgcg
    61381 taccgataga tttcatgatg ctacctcact tccttatttc tatgctcgta gtaaaaaggc
    61441 tcaactcagt aacagctaga aaacgagttt gtcttctaat ttcttgacgc agtcgctgcc
    61501 tggtttgaaa tgcgctctag caagcttttt caaacctagt catcgttgca ggggtaagac
    61561 gatgaaatcg aactcttcga gttaccgaat ctgcctcatt ttcttatttc taaactcggg
    61621 gttcaagatc ccccagacct tctctcactt tcttatttca agatgagagg ctgaaaacct
    61681 ccagtggagg tttttcttgc tttttaattt cagggcaaga agctaaaaag gtccccggac
    61741 cttcttcgct ttctcatttc taggctcagg gtaaaaacct ccaatggagg tttttactcc
    61801 caaaagtcat caaatacagt gatgggtaag tggcgtttgt gttggccttt gtgccaccag
    61861 ttttcaatgg tcgcttgagc ttctgggctg attgttttgc cttctaggta gtcgtcaatc
    61921 tctgcgtagg tgactccaag tgcgacttcg tcagctaggc ctggtttatc ttcttctagg
    61981 tctgccgttg ggattttttc ataaagggct ggctctgcgc caagtttctg caagagctgt
    62041 tttccttggc gtttattgag gcggtaaaga gggagaatat ccgcaccgcc gtcaccaaac
    62101 ttggtaaaga aacctgtgat attttccgcg gcgtggtctg ttccaatgac cgctccgcta
    62161 tgggaaccag caagggcata ctgagcaatc atacggcaac gtgccttgat attccccttg
    62221 ttgaagtctg aaacaggact acctgtcgct tcaactgcag ctgtcatggc atcagctgat
    62281 tccttgatat tcacaaccaa gctgacatct ggctggatga aggctagggc tttttgagca
    62341 tctgcttcat cagcttgcac tccgtatggc aggcggacag cgataaattt gtagctgtcg
    62401 tctcccgttt cagctcgcag ttcttccata gctaattgcg ccaaacgccc tgccaaggtt
    62461 gagtcttgtc ccccagaaat ccctagtaca aaggttttta ggaagggatg ttttttcaga
    62521 tatcttttta agaaatcaat agaacgacgg atttcttcct gggcatcaat cactggtttg
    62581 acacccagct cttggataat cgtttcttgc aaactcattc ttcttctcct tcaccaaggg
    62641 cttccttgcg catcttatca atcaagtcca tcttatcttg ccatacatca cgcgccaaat
    62701 ccactggata gtgctgcgga ttgagcacac gcttatactc atcccacaac ttgtcaaatt
    62761 ccttacgggc ataatcctga atgtcagtca aactaggcaa gttgtaaact aatattcctt
    62821 ctttgaagat atccaccaag agaggaacgg catcaaaatt acgaaccgtc ttcttgatgt
    62881 atgtataggt cggatggaac atcttgattt ctgtcatgtc gctaatatcc acaccatcat
    62941 aagtgatata gtcgccttct gacttgcctt tttcacgact ggtaatgcgc cacacctgct
    63001 tcttacctgg cgtagagact ttttccgcat tattagacag cttaatcgta ttgcgcatct
    63061 gaccagtttc atcttcgatt gcaacaatct tgtaaactgc accaagagct ggctggtcat
    63121 aagctgtaat cagcttggta cccacgcccc agacatcaat cttggccttt tgcatcttga
    63181 gattgaggat ggtattttca tctagatcat tagaagcata aatcttagcc tctgtaaatc
    63241 cagcctcatc cagttgctga cggactttct tagaaatgta ggcaatatcc ccagagtcaa
    63301 tccgcacacc cataaagtta atctgatcac ccagctcacg cgccacctga atggcagctg
    63361 gtacaccgat gcgaagggtg tcataggtat ccacaagaaa gacacaattt ttgtgggtcg
    63421 cagcgtaagc cttgaaagct tcatagtcat tgccataaac ctgtaccaag gcatgggcat
    63481 gggttcccaa aacaggaatg tcaaagagct tacccgcacg cacgttgctg gttccattgg
    63541 cgccaccaat cacagctgcg cgtgttcccc agatggccgc atccatttct tgagcccgac
    63601 gtgtcccaaa ctccatcaag ggttcatctt cgataaccga acgaatacga gctgccttcg
    63661 tcgccaccaa ggtctggtag ttgacgatgt tcaaaagagc cgtttcgacc aactgacatt
    63721 gggctagagg tccttccacc tgcacaatcg gttcattagc aaaaaccaaa tccccttctt
    63781 gggcagaacg aacggtcaac tccaacttga aattgcgaag gtaatccaag aacgccccat
    63841 gataaccaag cgactccaaa taggctatat cactatctga aaaacgcaag tcttcaagat
    63901 agttcacaat tctttccaaa cctgcaaaaa ccgcatagcc gttcttaaaa ggctgttggc
    63961 ggaaatacac ctcaaagacc gccttcttat tgtgaatccc ttggtcaaag taaacctgca
    64021 tcatgttgat ctggtacaag tccgtgtgca atgtcaaact atcatctgga tacatacttt
    64081 tcctacttcc ttagctagaa acccatgaaa attttcaaga actttcatgt attccaataa
    64141 attagtacta ttatatcaca ttttagctgg attgagaaaa gagtaacaag ctattctcca
    64201 ctctccaatt catccatatc ttgttcaaat tttttctgag cccattcgcc atagctctta
    64261 agaccaagat tgccaataaa gacccacgga aggtaaatga cataagtaat gacccaagca
    64321 gacaggtatt taaaattcaa aggattgtgc tgataaattt ctatgttgaa ttgataattc
    64381 tgcaacatca aaagagccgt aatagccaag gttaggaaaa aacaacccaa aatcgtaaaa
    64441 tgaaaacgac tatagtaggt cactcccaga taacgggcac ggttaaaaaa gtaaaatgtc
    64501 cctatgatga taacgattag cagcatatta gaattaaaaa ggcttggtgc taatactgaa
    64561 atgatataag ataggagcga caaagcgatg cagatataga aactttcaga gcccgcttta
    64621 ttgatcagtt gttcttctct ttcgtctagt aattgataat aataaaatct atttttcatc
    64681 ttcttcctcc caaaatagtt ggtctagggt tttccctaaa catctgcaaa tagactggca
    64741 gagcgagaga ctgggattgt attttcccgc ctctatcaaa ccaatagtct ggcgtgtcac
    64801 cccgacagcc tctgccagtt gaccttgtgt taaatcacgc tctacccgag ctaattttaa
    64861 ttttaaattt ttagccacct tcgtcctcct tatagtttta atactcatct actctttaaa
    64921 aatccaaact aacacaagct gtcagctatt tattataacc ccattaattt gcactccagt
    64981 attatcttca gccgaaaatc agtattttag gttgtttgaa ataaacttcc tagtttactc
    65041 ttttattttt atttttattt agcattagct ttagtaggat cttttaaacg agtttttatt
    65101 gcttatattt cttgtttagt ttagttggtt tcatatcact attatataat gcttttggaa
    65161 atgagcctag tataagtcaa aaacgtgttg aatagtgaaa gcaggagcat accaatatga
    65221 ctgatttttt actgtatttt aggtatgcaa aataatacta aatgaaacta aaatgaatac
    65281 ttcttgcttt tcttgagagt gaaaaagtac aataaaatga ttgtagtgat tgccacaaga
    65341 tactgactaa tagacatcgt atttgaagcc acaaatacag gtaaagaata aaaaggaaga
    65401 agttcaattg ctttgataaa caaatcatta ctagtattca tcatcgtatt taatatatta
    65461 gggataaaga gtagtaaagc tactaaaata ccaagccact tttcaatttg tataaataga
    65521 aaatgtaaga taatagaaaa taaaacagga ctaacaaaat tgtattgact acaatagcta
    65581 ctataaaatc taatcctaaa tcacctggaa tacccaattt acttactatg actagtaaca
    65641 caatgccatt caaagcataa ataatggaag ctgagatggc atatagaaaa ttagacaaga
    65701 cgtaaatcat ccgattcttc tgttgattat aaaacaaact taccgtattg tgggaaaaat
    65761 ctctactaat gactcgatta gcatgtataa cagccattaa cataccgagc atagcataaa
    65821 agtttgaaat atgcttaata ccaagcgatg tcccttaagt ctttagaata aagaatgtaa
    65881 gcaatatcgg cggtataaac gagataagca aactgagata tattacgcct gatgaatata
    65941 aatttcttat attttcctta agaaaattca atttatttaa tttcatgatt ataaccttcc
    66001 tttattttga acgatttagg taaatatctt taagcgtctc ttttttagtt tcaaaatcaa
    66061 ctactttaat agagttttcg ttaaaaaatt taaaaagctc actactttga atattcccag
    66121 acatagtaat tctcaatccc tcttcctgaa caatatcccc aaattcttgt ttggtaatga
    66181 aaatgtctct atctgtagct gatgaaaaag ctatctcaaa caagaaatta tgactatctt
    66241 ttcctacttt ttgaaatgtc aaaagcccgt tctccaagaa aagaactctc tcacaaattt
    66301 cttcaatgtc ttctaattta tgactcgata ttaaaattcc cacgttttca tttaaagcta
    66361 atttttttag aaccgctaaa actatttgtg atgattcaat atctaaacca ttagtcggtt
    66421 catctaaaat caatatatca ggttccgtaa cgagagttag aagcaaagct aatttttgtt
    66481 ttgtacccaa agaataggtc tttacttttt tattaataga ctgagtcaaa tctaactctt
    66541 ggatcaaact tctaaatctt tcttgattgt agtcaacacc atataaattt gacaaatatt
    66601 ttaaattctc taaacctgtt ttagataaaa ataattttgg ttcttcgatt aaatacccaa
    66661 cattatcact gcttataata ttacctgaag tcggttgatt attttgaaca agaattttca
    66721 tcaacgtact cttaccaact ccatttctcc ctactagacc aacaatttca cccttgttaa
    66781 gtgcaaaatt tatatctttg agaatgattg aatgaccata atgcttactt acatttttat
    66841 tcctacatta atattcatgg tttactcttt gattcttatt gagtttaaaa agttgcgcct
    66901 ctttttaaca atattatatc atatatctaa cttgatgcaa tatataaatg tcattttgta
    66961 aaattttatt aacaaaaaac tctctacaac aaaataatag agagttttct gcttattaat
    67021 ttttttcaaa atatctaaga catcgcttct ttgtttaatt tgataggctt tgatacctaa
    67081 gctccgactt tatcacttaa aaaataaaaa agacagctaa tctcttgcgc atcaagggat
    67141 ttcgccattc tttaatctcg tttaagtgtt gtatatggag ctttgcataa ttttttaaaa
    67201 ctaaacaact acattaagca cgaactgtga cgctggttcc atcttcctta taaagattga
    67261 taagcccctc tttaagagct cgaaccatgt ctcctgattg aacgggttgt gggactttaa
    67321 tagtcaatag ttccattgga tttggagcgc ggtcgatttt attgcctttg gcatcatgca
    67381 aatcttcaat ataggtttca aaatgacgga aacctggacc ataaaactca acttggtccc
    67441 cttcgttaat gacgtttcgt tgacgaatag ttgctgtttg tgccgcatca tcataagaaa
    67501 ccacttcagc gacaaacttg tactcaggga ttttacgacg agcaccaaac aactgctcat
    67561 tttcagatgg tgtaccatag taaaatcctg tagccagttc acgttgggca accttccaca
    67621 tctcgtccac caagtcttgt ttgatagctt caaacttttc aggactttca agataggcat
    67681 ccacaaccgc cttgtagcag ttggttactg ttaatacata gtgaatagac tccatacgtc
    67741 cttcgatttt tagactgtcc acaccatttt caatcatatc tggaatgtgg tcaatcatag
    67801 acatgtcaac ggctgacatt gaaaattctt ctggaatctc accctgcaaa ctcttacgtt
    67861 ctttcccaaa tggcatatcg taaaggtcgt atttccaacg gcatgactga gaacatccac
    67921 cacggttggc atcacgcata ctctagacgc aattctaatc ttttagactt tgcataataa
    67981 ctgttaaaca gttgaaaatt aacccagttt taacaagtag tcaaaatacc agataaagga
    68041 aaaaaagtct ttaaaatctt aaaaacgcat agtatcaggt attgaacaat cttgatatta
    68101 tgcgttttat tgtgggaaga tttacttcat tttctcttgg aattgagttt tctcctactt
    68161 caaaactaga tgatttgcta tttaaaatag cgttccttat gattttggca acctggatta
    68221 aagcgagaaa aacaaaaggg gcaacttaag ctttctttat attgcttata tgttagtagt
    68281 tttagacaaa caccacataa aataggctta tcctgtatca aagataaggg atacggctca
    68341 aaagggtgat tttctaatga atcatgacac cgataacaag catagtactt tttacaaaca
    68401 tagcattgta aagcaataat atccagcttg ctatggtaat gaatgcatct tgtttgctta
    68461 tccactaaga aaccctgtgc ctctatcatt tccttttcct ttcttaagct cgaactgtga
    68521 cgctggttcc atcttcctta taaagattga tgagtccttc ttttaatgca cgaaccatgt
    68581 ctccagcttg aacaggttga ggcaccttaa tagtcaatag ttccattgga tttggagcgc
    68641 ggtcgatttt attgcctttg gcatcatgca aatcttcaat ataggtttca aaatgacgga
    68701 aacctggacc ataaaactca acttggtccc cttcgttaat gacgtttcgt tgacgaatag
    68761 ttgctgtttg tgtcgcatca tcataagaaa ccacttcagc gacaaacttg tactcaggaa
    68821 ttttacgacg agcaccaaac aactgctcat tttcagatgg tgtaccatag taaaatcctg
    68881 tagccagttc acgttgggca accttccaca tctcgtccac taagttttgt ttgatggctt
    68941 caaacttttc agaactttca agataggcat ccacagccgc cttgtagcag ttggttactg
    69001 ttgatacgta gtgaatagac ttcatacgtc cttcgatttt tagactgtcc acaccatttt
    69061 caatcatatc tggaatgtgg tcaatcatag acatatcaac ggctgacatt gaaaattctt
    69121 ctagaatctc acccttcaaa ctcttacgtt ctttcccaaa tggcatatcg taaaggtcgt
    69181 atttccaacg gcatgactga gaacacccac cacggttggc atcacgcata ctcatgtggt
    69241 ttgaaagagt acaacgtcca gagtatgaaa tacacatagc tccatggaca aaggcttcaa
    69301 tttcaacatc tgtacgtttg cggatttcag ctaattcttt cattgaaacc tcacgtgcta
    69361 aaacgacacg agtcaagcct agctctttcc agaactcaag ggtttcatag ttagtggcac
    69421 tggcttgggt agaaaggtgg atttcaaggc ctggtgcttc agtcgctgca atcataatca
    69481 aggctgggtc agatacgata actgctgcaa tcccgatatc acgcagttta cgaaaccact
    69541 caccagcacc agcttcattt ccttcgtgca taaccatatt agccgctaca tagaccttgg
    69601 caccatactt ggccgcaaac tgcacgcctt cttccatctg ttcgaaagta aagtttcccg
    69661 cacggctacg aagaccatag gcctgaccac cgataaagac agcatctgct ccatactgaa
    69721 cagctacctt tagcttctct aaagtccctg caggtgataa aacctcagga cgttttaatg
    69781 tttttgtcat gatttctcct atttgcaata taaaagtttg acatttttcc ttctcatttt
    69841 atagtaaata aaggataaaa tcaagcctag acggattgtt ttgacaattc taatctttta
    69901 gactttgcat aataactatt aaacagtcga aaattacccc agttttaaca agtagtcaaa
    69961 aagtctaaaa aagtaaaaac cagtatccca agatactgac tcgtaaaaat atataaatta
    70021 gtccttagat gactactccc actctgttgc tcctataatg gaaaaggatt gatacagtct
    70081 agaatatcgc ttttttattt attattctga tataaaactg ttagaattga ttttttgttt
    70141 tatacccaaa tatgaataga gacgtagcta ataagttgaa taacatattt ggaaaaatga
    70201 gaaatagcaa tattactaga acttttagaa acaatcaata tttaaaaaga aaaaagctca
    70261 aagaatttat taaaccatgt tataatagat atagctataa ttttatttat aacaagagga
    70321 tagaaatgac cgaattagaa agaaaaaatc gaaaaattag ctaagaaata ttctgataac
    70381 ttaaacatca aagttcaaga gagagttcgt gaaatggcaa atgataataa gagccattat
    70441 ttgatataca gagttttagg tatttcattt gaagaaggag aaaatatcga tttgtatcaa
    70501 aataaaggtc gttttttata caaatatgct ggttcatttt tagaagaagc tgcagtacta
    70561 tcctttaacg aaaaatttgg tacagaaaat acttaaaaag ttaacattcc taattctgaa
    70621 aatacaaaac ctaagacttt tgaaattgat tgtttagtcg gagaaaaaca cgcatacgaa
    70681 ataaaatggt gggatgcaac tacagatgga gaccatataa ctaaagaaca cactagaata
    70741 aaagttattc ataacaaagg atatatacca attcggttaa tgttctacta tccaaataga
    70801 actcaagcta taaaaattca gcaaacttta gaaacattgt ataacggtat tggagggaaa
    70861 tattattatg gagattctgc ctgggaacat ttaagagcag tgaccggtat tgatttactt
    70921 agtattctaa cagatattgc aaataaaaaa acaggggtaa aatcaaaatg acagtattaa
    70981 aaggagataa cttagaaata ttaaaaacta ttgaatcctc aagtattgat ttaatctata
    71041 tggaccctcc tttctttaca cagaaaaccc aaaaattatc taataacaaa aatattatgt
    71101 attcattcga agatacgtgg acttcgattg aggattacaa agaatttttg tctgtaagat
    71161 tagaagaatg caaaagagtg ctaaaaaata gtggcagtat tttcgttcat tgtgataaaa
    71221 ttgcaaatca tcatattaga ttaattttag ataatatctt tggagcagat atgtttcaaa
    71281 gcgaaattat atggaactat aaacggtggt ctaattcaaa aaagggatta ttgaacaatc
    71341 atcaaaacat ttacttttat tcaaagtcaa aagattttaa atttaataca atttttacag
    71401 agtattcttc tactacaaat atcgaccaaa tactagtaga acgaaaacga aatggaaact
    71461 ctaaaactat atataaagtt gataataatg gtaactatat tctagcaaaa gagaaaaatg
    71521 gagttcccct ttcagatgtt tggaatatac catttcttaa tccaaaagct aaagaaagag
    71581 taggttatcc tacacaaaaa cctattctgt tattagaaca aattataaag attgctactg
    71641 ataaaaatga tatagtttta gacccgttct gtggaagtgg aactacttta gtagcctcca
    71701 agattttgaa tagaaattat atggggattg atttatctga ggaagctatc aatataactc
    71761 agcaacgtct ggaaaatgtt ataaaaacaa gttcaaattt attgaataaa ggaatcgaag
    71821 catatagaac caaaactgag gaagaggaaa acattcttaa attattacag gcaaaaattg
    71881 ttcaaagaaa taaaggaatt gatggttttt tacctaaaca ttttcaaaaa aaaccgatac
    71941 ctataaaaat tcaaaaaaat aatgaatgtc tgaatgagag tatctcttta ttacagaatg
    72001 ctataaactc caaaaaactt gattttggag tagttataaa aactcattca gataatttat
    72061 tatttgattt tgatacgatt cctgaaaata taatagtagt tgaccatttt gaacttacaa
    72121 tcgaaaaatg gttaagtaaa agtcaacagt tactatagtt tgcaaattat ttacagaaag
    72181 aacaaaaaat gctctgaaac actgatttca aggcattttt tgttagttta aaattactcc
    72241 cattcttctt ttccaaacgt acaatatatc caaaaccatt caaaatacta gattctattt
    72301 tttataatat cactaaatcc acctaattat aggacgtttt cagattttta gtcccgtccc
    72361 agtcccagta ccggagaaat attgttttaa tataatatct ctttttgtct tctaagctct
    72421 taaaagcaaa agaacaagta aagagtcaag acaaggataa aaagtccata ttagggcaaa
    72481 taaaaagctt taagacagat gacaaatcta agtcaaataa gaaagaccat agcaaaggtg
    72541 cagagagata aatattggcg gtcttcggac tgcctttatt tttttatcca tttttcaaat
    72601 caaatttatt cagactatat atgcacatat acacttaaat tcatataaaa acatggcttg
    72661 taaaaaatta ctttaatcac aataatcgca tttaaaattg tgatgtttgc aagctaaatt
    72721 acggacttca cttggaagtt ttcccttgta tcttttataa tagatagaaa atttgctggc
    72781 agatgaatat ccaacagatt ctgctatctc ttttataggt agttcagtgt ttaaaagaag
    72841 agtttcagct acattcattc tttttctttg agtgtactct gtaatgcttt gacaatattt
    72901 ttccttaaat aaatttttta atttagtacc actcatttta gatatttttt caagcgtgcc
    72961 ttgatttaca ttcgttgcaa aatgatcatc taagaatctt gctacatctt caagtgcttt
    73021 atcatcatca atttcaattt tatatttttt tctatttaag tatgtgtcaa ttactatact
    73081 tatccattca tttgcctttg ctttaaagaa aaaatcagcg gcaggagcgt ccatcttaca
    73141 atttaatatt tccattgcca ctctttctaa ggcctttgta agtattattt gattcggttg
    73201 aagcaaggtt gaataaaaag attctggatt aatgttaata gatgctaaat gtttttctat
    73261 tagctctttt ttaaaaccaa tggaaacagc aagataacaa caattctcgt gtaataaaaa
    73321 aacaaaatca tcttttatat tatcaaaatc aaaagtacat aaagagtttg cggtaatagt
    73381 ttgatacgga ttaaactttt ctccgtttgc actgacaatg taacttgaat aaattgaaac
    73441 atagtctgac atactataag tgctattttg aactacttcc tctttgatat aaaaatcatg
    73501 tatatcgata atgaagctgc ctccttcata aaaccaatat aggccttctg cataagttga
    73561 attctctttt ttccaacaaa atgtatgacc tgcacttgaa tacttctcat tgtttttaca
    73621 ttcatctact ttcatataat cttttacaaa atcataatat gacataacac actatccctt
    73681 ttagacaata ttccaattag ccttattaat tcaaaactat tgtattagta attataacag
    73741 atgtataata gaaaagcaat gatagatatt atcaattaag cgaatttata tctaaaaggg
    73801 atattaaaga aaggagatat gcttatgaag atttacaaaa aactatttgc ttatgtccaa
    73861 gataagaaat atcttggggt tttggccata attttttctg ctatatctgc tgtacttaca
    73921 gtatatggat attatttaat ctacaaattt ctagataagt taataattaa ttcaaactta
    73981 tccggtgcag agagtatagc attaaaatct gttattacac taacaagtgg agcgatattt
    74041 tattttgtct caggaatgtt ttcacatatc ttgggattta ggcttgaaac aaatttaaga
    74101 aaaaggggaa tcgatggtct ggaaaaagca agttttaggt tctttgactt aaatccatct
    74161 ggtcaaataa gaaagatcat agatgataat gcagcacaaa ctcatcaggt ggtagctcac
    74221 atgattccag atagctctca ggcaatagtc acacctatac ttgtccttgt acttggcttt
    74281 atagtaagta taagagttgg cataattttg cttgctctta ctataattgg tggcttaatt
    74341 ttaggggcaa tgatgggcga gcaagaattt atgaagatat accaagaatc cctatctaaa
    74401 ctaagtgctg aaactgttga gtacgtgaga ggaatgcaag ttgtaaaaat atttaaagca
    74461 aatgtagagt cttttaaaag cttttataag gcgataaaag attactcaaa gtatgcttat
    74521 gattattccc tatcttgtaa aaggccttat gttttgtatc aatggttatt ttttggactg
    74581 attgcaattt taattattcc tatagtttat tttatgacta gcttagctag cgcagaggtg
    74641 attttacttg agcttatcat gattttattt ttatcaggag ttctctttgt ttcattcatg
    74701 agaatgatgt ggtactccat gtatatttct caaggaaatt atgcagtaga tactttagag
    74761 gcgctttacg aagatatgca aaaagacaaa ttagtgcatg gtaatgtcaa taattttaaa
    74821 aactataata tagaatttga gaatgttagc tttgcttata atgataaagc tatcattgaa
    74881 aatttatcct ttaatttaga agaaggaaag tcctacgcac ttgtcggttc atctggatca
    74941 ggcaaatcaa cagtagcaaa acttatatca ggtttttaca atgttaataa aggaagcata
    75001 aagataggcg ggatagcaat aagtgaatat tctgacgaag ccttaattaa agccatttcc
    75061 tttgtttttc aagattcaaa attattcaag aagagcattt atgataatgt agctttagct
    75121 aataaagatg cgacgaaaga tgacgttatg agagccttaa aattagcagg atgcgattta
    75181 atattagaca aattcccaga aagagaaaat acaatcatag gctcaaaagg tgtttattta
    75241 tccggtggag aaaaacaaag aattgcaatt gctagagcaa ttttaaagga ttccaaaatt
    75301 attattatgg atgaagcatc agcatctatt gacccagata acgagtttga attgcaaaaa
    75361 gcttttaaaa atcttatgaa ggataaaaca gttatcatga ttgcacacag gctatctaca
    75421 attaaagacc ttgatgaaat tattgtcatg gatagtggaa aaattataga aagagggtct
    75481 gacaaagaat taatgtcaaa agatacaagg tataagagcc tgcaagagat gtttaacagt
    75541 gcgaatgaat ggagggtttc aaatgaaaga gttttataaa aaaagatttg ctcttacaga
    75601 tggaggagca agaaatttaa gtaaagcaac actggcttca tttttcgttt attgtataaa
    75661 catgcttcct gccatattac ttatgatttt tgctcaggaa gttttggaaa atatgggcaa
    75721 aagcaatggc ttttatatag tattctcagt tttgactttg atagcaatgt atattttgct
    75781 ttctatcgaa tacgataaat tatataacac aacctatcaa gaaagtgcag atttaagaat
    75841 aaggacagcg gagaatttat caaaattacc tctatcttac ttttctaaac atgacatttc
    75901 cgacatttca caaacaatca tggctgatat tgaaggcata gagcatgcaa tgagccactc
    75961 aataccaaag gtgggcggca tggtactgtt tttcccatta atatctgtaa tgatgctagc
    76021 gggcaatgtc aagatgggtt tagctgtaat tattccatct attttaagct ttatatttat
    76081 acctttatct aaaaaatatc aggttaatgg acagaataga tattatgatg tcttaagaaa
    76141 aaactcagaa agctttcaag aaaatatcga aatgcaaatg gagattaaag catataattt
    76201 atcgaaggat attaaagatg acttatataa aaaaatggaa gatagtgaga gaatacactt
    76261 aaaggcggaa gtaactacaa ttttaacttt gtctatatct tcaatattta gctttatatc
    76321 tcttgctgtt gtgatatttg tcggcgtaaa tctaattatt aataaagaga taaattctct
    76381 ctaccttata ggatatttac tagctgctat gaagataaaa gactctttag atgcatctaa
    76441 agagggcttg atggaaatat tttatttatc gcccaaaata gaaagattaa aagaaattca
    76501 aaatcaagat ttacaagaag gcgatgacta tagcttaaaa aaatttgata ttgatctaaa
    76561 agatgttgag tttgcctaca ataaagacgc aaaagtttta aatggtgtaa gttttaaagc
    76621 taagcaggga gaggtcactg ctttggtagg tgcaagtggc tgcggtaaaa caactatctt
    76681 gaaacttata tcaagacttt atgattatga caagggacaa atcttaatcg atggcaaaga
    76741 tataaaagaa atatcaacag aatctctttt tgataaggtc tctatagttt tccaagatgt
    76801 ggttctcttt aatcaaagcg ttatggaaaa tattagaatc ggtaagcaag atgcaagtga
    76861 cgaagaggtt aaaagagcag caaaacttgc aaattgcaca gattttatag aaaaaatgga
    76921 taaaggtttc gatacagtta ttggtgaaaa cggagctgag ctatcaggag gagaaagaca
    76981 aagattatca atagccagag ccttcttaaa agatgcgccg atattgatct tagatgagat
    77041 aacagcaagc cttgatgtta acaacgagaa aaagattcaa gagtctttaa ataatttagt
    77101 taaagataaa actgttgtaa tcatttcaca tagaatgaaa tccatagaaa atgcagacaa
    77161 gatagtagtt cttcaaaacg gaagagtaga aagcgaaggt aagcatgaag agcttttaca
    77221 aaaatcaaaa atttacaaaa atttaataga aaagacaaaa atggcagaag aatttattta
    77281 ttaggaggac tacaatggat aataaaaaat taaaagtaaa agatttagta agtatcggtg
    77341 tttttggcgt aatttatttt gccttcatgt ttggagttgg tatgatgggc ttgattccaa
    77401 tattgttctt aatatacccg acagtattag ccatagttgc aggaactgtt gttatgttat
    77461 ttatggctaa ggttcaaaag ccatgggcac tatttatatt tggtatgata tcaccacttg
    77521 tgatgtttgc agctggtcat acctacgtag ttgtggtttt atcacttata gtaatgataa
    77581 tagcagaatt aattagaaag attggtaatt ataattcatt taaatacaat atgctttctt
    77641 atgcaatctt cagcacatgg atatgtagct ctttaatgca aatgctttta gcaaaagaaa
    77701 aatatatgga gtggtctttg atgacgatgg gaaaagatta tgttgatgta ttagaaaagt
    77761 taataactta tcctcacatg gctttaatag ccttaggtgc tttcttagga ggaattcttg
    77821 gagcatatat aggcaaggct ctattgaaaa aacacttttc aaatggatta tattgtgtgg
    77881 gatactttac tccttgccta attttatggt gttatctgaa ttaaacccta tagttaagat
    77941 gtttttgagt atacctattg ttattagaat gtttatttta ccatttatgg cagcaagctt
    78001 tatgataaag acctcggatg taggcgcaat aatttcatcg atggataagc ttaagatttc
    78061 aaagaatgta tccataccta ttgcggttat gtttagattc ttcccatctt ttaaggagga
    78121 gaagaaaaac atcaaaatgg ctatgagagt aagagggata aattttaaaa acccagtcaa
    78181 atatcttgaa tatgtttctg tgccactact cattatatca tctaatatat cagatgacat
    78241 tgcaaaagcg gcagaaacaa aggcaataga aaatccaatt gccaagacca gatacattcg
    78301 cgtaaagata cagctaattg attttgttta tgttttagcg gttgctggac ttattgtggg
    78361 aggcttaata tggttgaaat aaaaaattta agtcttgatt atggtgaaga gcatatatta
    78421 gatgatatat cactatccat agccgaggga gagtgcgtgc tatttacagg aaaaagtgga
    78481 agtggtaagt catctttaat aaattcaatc aatggactag ctgtaaggta tgataacgca
    78541 aagacaaagg gcgaaataat tattgatggt aagaatataa aaaatttgga actttatcaa
    78601 atctcaatgc ttgtttcaac tgtttttcaa aatcctaaga catatttttt taatgtcaat
    78661 acgacattag aattattatt ttatttggaa aatatcggtc ttgcaagaga agagatggac
    78721 aggcgtttga aggatatact tgagatattc ccgataaaaa atcttttgaa cagaaatata
    78781 tttaatctat ccggcggtga aaaacaaatt ctttgcattg cagcttctta tatagcaggt
    78841 acaaagatta tagttatgga tgagtcttca tcgaatttag atattaaaag cataagtgtt
    78901 ttggcaaaga tgctaaagat attaaaagag aaaggcataa gcataattgt tgcagagcat
    78961 agaatttatt atttgatgga catagttgac cgtgtatttt taatagataa aggaaagctt
    79021 aaaaaaactt atactagaag tgaattttta aagctagata aaaatgaatt aaatgcttta
    79081 agtttaagag ataaagaatt aagtaaatta aaagttcctt atttaaaaga aggtggagag
    79141 tatcagataa aaaatcttag ctacaaattt actgatgatg agtgtttaag cttaaaagat
    79201 atttcgttca agcttgggaa aatttatggc ataataggat ccaacggacg aggaaaatca
    79261 acgcttttaa gatgtttaat aggtcttgag aaaaaatcaa aagaagaaat ttattttaag
    79321 ggagagaagc tatctaaaaa agaaagactc aaaaactctt cacttgttat gcaagatgta
    79381 aatcatcaat tattcacaga tgaagtattc aacgagctta gattaggagt aaagaatttt
    79441 gatgaagaaa aggcgaaaat cattttaaaa gatttaggcc tggacgaatt tattgaaagg
    79501 catccgatga gtttatcagg agggcaaaag caaaggcttg caatagcatc tgttatgtgc
    79561 aagacttctc catttatctt ttttgacgaa ccttcaagtg gtatagatta ttccaatatg
    79621 ataaaaatat ctgaactgat taataagtat aaaaccatgg ataaaataat ttttattgtt
    79681 tcccatgata tagaattttt aaatgaagtg gcagatgaaa tttttgaatt gtaaaataga
    79741 gtctgttaaa catgtctata gaactggtaa attgtctaaa aatttaaaag atactaacac
    79801 atattgatat ttattagaaa attaacttca ggatttttac agtatttata aactttataa
    79861 tatgtattta tagtattaat aatttccata tctttaggga aattatttat ttacttacca
    79921 taattaaaga gatgagagat aaatatcggc agtcttcgga ctgcctttat ttttttactt
    79981 aatttaatgc agtaaatcat acgattgaaa ggaatctgcg ttatatgcta taattaggta
    80041 gttaatctat acatttagaa aggtaaaata tagaattgga gaatgatatg ggattttcat
    80101 ataataaatt gtaaccaccc aataacgaag tctattgaaa aatctccaga ttagtgaact
    80161 cacggatagt tcctaatctg gagatttctt atttgcactt ttcttgtaca actttagtcc
    80221 atggtaaata agcctctaaa acctctttgt ttacgagagt ttcctcgttt ggaagacatt
    80281 ctagaagata ggatagatat ttctcgctat ttataatgga ttgaaataag atatgaacaa
    80341 atcgattagg aaaggaaaat tgatttatag aaatatttta gcagtcgatg cgtactgtta
    80401 tagattcaac gcactataat tgatgacgtt tagctgtttc caacaaactc at
//
LOCUS       DAVBBO010000003        79153 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ST1
            SAMEA2066453-rid20184263.denovo.003, whole genome shotgun sequence.
ACCESSION   DAVBBO010000003 DAVBBO010000000
VERSION     DAVBBO010000003.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2066453
            Sequence Read Archive: ERR351777
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 79153)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 79153)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980402.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980402.1
            Genome Coverage       :: 176x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:17:33
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,141
            CDSs (total)                      :: 2,104
            Genes (coding)                    :: 1,953
            CDSs (with protein)               :: 1,953
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 16S)
            partial rRNAs                     :: 1 (23S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 151
            CDSs (without protein)            :: 151
            Pseudo Genes (ambiguous residues) :: 0 of 151
            Pseudo Genes (frameshifted)       :: 73 of 151
            Pseudo Genes (incomplete)         :: 76 of 151
            Pseudo Genes (internal stop)      :: 40 of 151
            Pseudo Genes (multiple problems)  :: 32 of 151
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..79153
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2066453-rid20184263.denovo.003"
                     /strain="ST1"
                     /db_xref="taxon:1313"
     gene            <1..107
                     /locus_tag="VQU30_000157"
     CDS             <1..107
                     /locus_tag="VQU30_000157"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001841243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HET2446350.1"
                     /translation="KRGSPHLRWALIQAAKACPRFSPAFKAYLKTKLE"
     gene            complement(408..2297)
                     /locus_tag="VQU30_000158"
     CDS             complement(408..2297)
                     /locus_tag="VQU30_000158"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000750662.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2207 domain-containing protein"
                     /protein_id="HET2446351.1"
                     /translation="MKKTFFLLVLGLFCLLPLSVFAIDFKINSYQGDLYIHADNTAEF
                     RQKIVYQFEEDFKGQIVGLGRAGKMPSGFDIDPHPKVQAAKNGAELADVTSEVTEEAD
                     GYTVRVYNPGQEGDIVEVDLVWNLKNLLFLYDDIAELNWQPLTDSSESIEKFEFHVRG
                     DKGAEKLFFHTGKLFREGTIEKSNLDYTIRLDNLPAKRGVELHAYWPRTDFASARDQG
                     LKGNRLEEFNKIEDSIVREKDQSKQLVTWVLPSILSISLLLSVCFYFIYRRKTTPSVK
                     YAKNHRLYEPPMELEPMVLSEAVYSTSLEEVSPLVKGAGKFTFDQLIQATLLDVIDRG
                     NVSIISEGDAVGLRLVKEDGLSSFEKDCLNLAFSGKKEETLSNLFADYKVSDSLYRRA
                     KVSDEKRIQARGLQLKSSFEEVLNQMQEGVRKRVSFWGLPDYYRPLTGGEKALQVGMG
                     ALTILPLFIGFGLFLYSLDVHGYLYLPLPILGFLGLVLSVFYYWKLRLDNRDGVLNEA
                     GAEVYYLWTSFENMLREIARLDQAELESIVVWNRLLVYATLFGYADKVSHLMKVHQIQ
                     VENPDINLYVAYGWHSLFYHSSAQMSHYASVANTASTYSVSSGSGSSGGGFSGGGGGG
                     SIGAF"
     gene            2435..4000
                     /locus_tag="VQU30_000159"
     CDS             2435..4000
                     /locus_tag="VQU30_000159"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001227294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding
                     protein/permease"
                     /protein_id="HET2446352.1"
                     /translation="MRKIYLSIFTSLLLMLGLVNVAQADEYLRIGMEAAYAPFNWTQD
                     DDSNGAVKIDGTNQYANGYDVQIAKKIAKDLGKKPLVVKTKWEGLVPALTSGKIDMII
                     AGMSPTAERKQEIAFSSSYYTSEPVLLVKKDSAYASAKSLDDFNGAKITSQQGVYLYD
                     LIAQIPGAKKETAMGDFAQMRQALEAGVIDAYVSERPEALTAEAANSKFKMIQVEPGF
                     KTGEEDTAIAIGLRKNDNRISQINASIETISKDDQVALMDRMIKEQPAEATTTEETSS
                     SFFSQVAKILSENWQQLLRGAGITLLISIVGTIIGLIIGLAIGVFRTAPLSENKAIYG
                     LQKLVGWVLNVYIEIFRGTPMIVQSMVIYYGTAQAFGINLDRTLAAIFIVSINTGAYM
                     TEIVRGGILAVDKGQFEAATALGMTHNQTMCKIVLPQVVRNILPATGNEFVINIKDTS
                     VLNVISVVELYFSGNTVATQTYQYFQTFTIIAVIYFVLTFTVTRILRFIERRMDMDTY
                     TTGANQMQTEDLK"
     gene            4000..4764
                     /locus_tag="VQU30_000160"
     CDS             4000..4764
                     /locus_tag="VQU30_000160"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000189471.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HET2446353.1"
                     /translation="MTQAILEIKHLKKSYGQNEVLKDISLTVHKGEVISIIGSSGSGK
                     STFLRSINLLETPTDGQILYHGQNVLEKGYDLTQYREKLGMVFQSFNLFENLNVLENT
                     IVAQTTVLKRERTEAEEIAKENLEKVGMGERYWQARPKQLSGGQKQRVAIARALSMNP
                     DAILFDEPTSALDPEMVGEVLKIMQDLAQEGLTMIVVTHEMEFARDVSHRVIFMDKGV
                     IAEEGKPEDLFTNPKEDRTKEFLQRYLILNENQRAN"
     gene            complement(4963..5178)
                     /locus_tag="VQU30_000161"
     CDS             complement(4963..5178)
                     /locus_tag="VQU30_000161"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002893653.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2446354.1"
                     /translation="MAKSNFEKVESVVGWVRDKKITGYRISKETNAREMSIIALAQGR
                     AKVKNISFETALGLIDFYEKNHEKFED"
     gene            complement(6049..7299)
                     /gene="ilvA"
                     /locus_tag="VQU30_000162"
     CDS             complement(6049..7299)
                     /gene="ilvA"
                     /locus_tag="VQU30_000162"
                     /EC_number="4.3.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006151817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine ammonia-lyase IlvA"
                     /protein_id="HET2446355.1"
                     /translation="MLSSKDIIKAHKVLNGVVVNTPLDYDHYLSEKYGAKIYLKKENA
                     QRVRSFKIRGAYYAISQLSKEERERGVVCASAGNHAQGVAYTCNEMKIPATIFMPITT
                     PQQKIGQVRFFGGDFVTIKLVGDTFDASAKAAQEFTVSENRTFIDPFDDAHVQAGQGT
                     VAYEILEEARKESIDFDAVLVPVGGGGLIAGVSTYIKETSPEIEVIGVEANGARSMKA
                     AFEAGGPVKLKEIDKFADGIAVQKVGQLTYEATRQHIQTLVGVDEGLISETLIDLYSK
                     QGIVAEPAGAASIASLEVLAEYIKGKTICCIISGGNNDINRMPEMEERALIYDGIKHY
                     FVVNFPQRPGALREFVNDILGPNDDITRFEYIKRASKGTGPVLIGIALADKHDYAGLI
                     RRMEGFDPAYINLNGNETLYNMLV"
     gene            complement(7349..7705)
                     /locus_tag="VQU30_000163"
     CDS             complement(7349..7705)
                     /locus_tag="VQU30_000163"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001027901.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ketol-acid reductoisomerase"
                     /protein_id="HET2446356.1"
                     /translation="MNITNLFSIKTGCDETDRQLQKLFFQLDLQLGELTDQLRKLDSN
                     FVPRSQFVDTLDLNDVEYKEILNYFIFHRNDSEESLVEWLYDWISTNRYELPKEFSIR
                     MAHKYHESVTEVFGDE"
     gene            complement(7943..8179)
                     /locus_tag="VQU30_000164"
     CDS             complement(7943..8179)
                     /locus_tag="VQU30_000164"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001813675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2446357.1"
                     /translation="MLADQNKADWSYDENAVINIYDDANFEDGRLHMTFEQFFKLAQI
                     AREEGLEIHSPFERAGATKSARYIAKWILRNKKH"
     gene            complement(8286..9308)
                     /gene="ilvC"
                     /locus_tag="VQU30_000165"
     CDS             complement(8286..9308)
                     /gene="ilvC"
                     /locus_tag="VQU30_000165"
                     /EC_number="1.1.1.86"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006145054.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ketol-acid reductoisomerase"
                     /protein_id="HET2446358.1"
                     /translation="MTVQMEYEKDVKVAALDGKKIAVIGYGSQGHAHAQNLRDSGRDV
                     IIGVRPGKSFDKAKEDGFDTYTVVEATKLADVIMILAPDEIQQELYEAEIAPNLEAGN
                     AVGFAHGFNIHFEFIKVPADVDVFMCAPKGPGHLVRRTYEEGFGVPALYAVYQDATGN
                     AKNIAMDWCKGVGAARVGLLETTYKEETEEDLFGEQAVLCGGLTALIEAGFEVLTEAG
                     YAPELAYFEVLHEMKLIVDLIYEGGFKKMRQSISNTAEYGDYVSGPRVITEQVKENMK
                     AVLADIQNGKFANDFVNDYKAGRPKLTAYREQAANLEIEKVGAELRKAMPFVGKNDDD
                     AFKIYN"
     gene            complement(9374..9850)
                     /gene="ilvN"
                     /locus_tag="VQU30_000166"
     CDS             complement(9374..9850)
                     /gene="ilvN"
                     /locus_tag="VQU30_000166"
                     /EC_number="2.2.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002927678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetolactate synthase small subunit"
                     /protein_id="HET2446359.1"
                     /translation="MRRMLTAKLQNRSGVLNRFTGVLSRRQVNIESISVGATEDPNVS
                     RITIIIDVASHDEVEQIIKQLNRQIDVIRIRDITDKPHLEREVILVKMSAPAEKRAEI
                     LAIIQPFRATVVDVAPSSITIQMTGNAEKSEALLRVIRPYGIRNIARTGATGFTRD"
     gene            complement(9843..11543)
                     /locus_tag="VQU30_000167"
     CDS             complement(9843..11543)
                     /locus_tag="VQU30_000167"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000411733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetolactate synthase large subunit"
                     /protein_id="HET2446360.1"
                     /translation="MEKISLESPKTGSDLVLETLRDLGVDTIFGYPGGAVLPFYDAIY
                     NFKGIRHILGRHEQGCLHEAEGYAKSTGKLGVAVVTSGPGATNAITGIADAMSDSVPL
                     LVFTGQVARAGIGKDAFQEADIVGITMPITKYNYQVRETADIPRIITEAVHIATTGRP
                     GPVVIDLPKDISALETDFIYSPEVNLPSYQPTLEPNDMQIKKILKQLSKAKKPVLLAG
                     GGISYAEAATELNEFAERYQIPVVTSLLGQGTIATSHPLFLGMGGMHGSFAANIAMTE
                     ADFMISIGSRFDDRLTGNPKTFAKNAKVAHIDIDPAEIGKIISADIPVVGDAKKALQM
                     LLAEPTVHNNTEKWIEKVTKDKNRVRSYDKKERVVQPQAVIERIGELTNGDAIVVTDV
                     GQHQMWTAQYYPYQNERQLVTSGGLGTMGFGIPAAIGAKIANPDKEVVLFVGDGGFQM
                     TNQELAILNIYKVPIKVVMLNNHSLGMVRQWQESFYEGRTSESVFDTLPDFQLMAQAY
                     GIKNYKFDNPETLAQDLEVITEDVPMLIEVDISRKEQVLPMVPAGKSNHEMLGVQFHA
                     "
     gene            complement(11744..13411)
                     /locus_tag="VQU30_000168"
     CDS             complement(11744..13411)
                     /locus_tag="VQU30_000168"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000036655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DAK2 domain-containing protein"
                     /protein_id="HET2446361.1"
                     /translation="MSKITTSLFQEMVQAASTRLNKQAEYVNSLNVFPVPDGDTGTNM
                     GMTIENGAKEVADKPASTVGEVASILAKGLLMGARGNSGVITSQLFRGFSQAIKDKDE
                     LTGQDLALAFQSGVEVAYKAVMKPVEGTILTVSRGAAIGAKKKAEQTDDTVEVMRAAL
                     EGAKTALAKTPDMLPVLKEVGVVDSGGQGLVFIYEGFLSALTGEYIASEDFVATPANM
                     SEMINVEHHKSVAGHVATEDITFGYCTEIMVALKQGPTYAKDFDYDEFRNYLDELGDS
                     LLVVNDDEIVKVHVHTEDPGLVMQEGLKYGSLVKVKVDNMRNQHEAQVEKEATQVIKS
                     AEEKEYALIAVVAGKGLADIFCSQGVDYVIEGGQTMNPSTEDFIKAVEQVNARNIIFL
                     PNNKNIFMAAQSAAEVLEQPAVVVEARTLPQGMTSLLAFDPSKSIEENQERMTAALSD
                     VVSGSVTTAVRDTTIDGLEIHENDNLGMVDGKILVSNPDMHQTLTETLKHMLDEDSEI
                     VTFYVGEDGSEELANEIAQEIVEEFEDVEVEIHQGQQPVYPYLFSVE"
     gene            complement(13414..13779)
                     /locus_tag="VQU30_000169"
     CDS             complement(13414..13779)
                     /locus_tag="VQU30_000169"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018371966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HET2446362.1"
                     /translation="MTVKINTKDGQIELTDEVIATVVGGAATEIFGVVGMASKNALKD
                     NFQALLGKENYSKGVVVKAAEDGSIAVDVYTVLSYGTKISEVSKNIQERVAFSLENQL
                     GITAQTVNVYIQNIKVVGE"
     gene            complement(13936..14124)
                     /locus_tag="VQU30_000170"
     CDS             complement(13936..14124)
                     /locus_tag="VQU30_000170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008536053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L28"
                     /protein_id="HET2446363.1"
                     /translation="MAKVCYFTGRKTVSGNNRSHAMNQTKRAVKPNLQKVTVLIDGKP
                     KKVWASARALKSGKVERV"
     gene            complement(14240..14416)
                     /locus_tag="VQU30_000171"
     CDS             complement(14240..14416)
                     /locus_tag="VQU30_000171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001858191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl transferase family 8"
                     /protein_id="HET2446364.1"
                     /translation="MDSDIVVRKSIDELWDLDLTAIPLAAVRDDFYTHNFNSGVLLIN
                     DGMWRAENVTQDLI"
     gene            complement(14527..14676)
                     /locus_tag="VQU30_000172"
     CDS             complement(14527..14676)
                     /locus_tag="VQU30_000172"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001808887.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl transferase family 8"
                     /protein_id="HET2446365.1"
                     /translation="MDKVETTIKSLCVHHYNLKFYVFNDDLPREWFQLMEKRLETLNS
                     EIVNV"
     gene            complement(14988..16532)
                     /locus_tag="VQU30_000173"
     CDS             complement(14988..16532)
                     /locus_tag="VQU30_000173"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011681503.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 3"
                     /protein_id="HET2446366.1"
                     /translation="MNIQEEIKKRRTFAIISHPDAGKTTITEQLLYFGGEIREAGTVK
                     GKKTGTFAKSDWMDIEKQRGISVTSSVMQFDYDGKRVNILDTPGHEDFSEDTYRTLMA
                     VDAAVMVVDSAKGIEAQTKKLFEVVKHRGIPVFTFMNKLDRDGREPLDLLQELEEILG
                     IASYPMNWPIGMGKAFEGLYDLYNQRLELYKGDERFASLEDGDKLFGSNPFYEQVKDD
                     IELLNEAGNEFSEEAILAGELTPVFFGSALTNFGVQTFLEIFLKFAPEPHGHKKTDGE
                     IVDPYDKDFSGFVFKIQANMDPRHRDRIAFVRIVSGEFERGMSVNLPRTGKGAKLSNV
                     TQFMAESRENVINAVAGDIIGVYDTGTYQVGDTLTVGKNKFEFEPLPTFTPEIFMKVS
                     AKNVMKQKSFHKGIEQLVQEGAVQLYKNYQTGEYMLGAVGQLQFEVFKHRMEGEYNAE
                     VVMNPMGKKTVRWIKPEDLDERMSSSRNILAKDRFDQPVFLFENDFALRWFADKYPDV
                     ELEEKM"
     gene            16745..17047
                     /gene="gatC"
                     /locus_tag="VQU30_000174"
     CDS             16745..17047
                     /gene="gatC"
                     /locus_tag="VQU30_000174"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006147946.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase
                     subunit GatC"
                     /protein_id="HET2446367.1"
                     /translation="MKITQEEVTHVANLSKLRFSEEETAAFATTLSKIVDMVELLGEV
                     DTTGVAPTTTMADRKTVLRPDVAEEGTDRDRLFKNVPEQDNYYIKVPAILDDGGDA"
     gene            17047..18513
                     /gene="gatA"
                     /locus_tag="VQU30_000175"
     CDS             17047..18513
                     /gene="gatA"
                     /locus_tag="VQU30_000175"
                     /EC_number="6.3.5.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466749.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase
                     subunit GatA"
                     /protein_id="HET2446368.1"
                     /translation="MTFNNKTIEELHNLLVSKEISATELTQATLENIKSREEALNSFV
                     TIAEEQALVQAKAIDEAGIDANNVLSGIPLAVKDNISTDGILTTAASKMLYNYEPIFD
                     ATAVANAKTKGMIVVGKTNMDEFAMGGSGETSHYGATKNAWDHSKVPGGSSSGSAAAV
                     ASGQVRLSLGSDTGGSIRQPAAFNGIVGLKPTYGTVSRFGLIAFGSSLDQIGPFAPTV
                     KENALLLNAIASEDTKDSTSAPVRIADFTSKIGQDIKGMKIALPKEYLGEGIDPEVKE
                     TILNAAKHFEKLGAIVEEVSLPHSKYGVAVYYIIASSEASSNLQRFDGIRYGYRAEDA
                     TNLDEIYVNSRSQGFGEEVKRRIMLGTFSLSSGYYDAYYKKAGQVRTLIIQDFEKVFA
                     DYDLILGPTAPSVAYDLDSLNHDPVAMYLADLLTIPVNLAGLPGISIPAGFSQGLPVG
                     LQLIGPKYSEETIYQAAAAFEATTDYHKQQPVIFGGDN"
     gene            18513..19955
                     /gene="gatB"
                     /locus_tag="VQU30_000176"
     CDS             18513..19955
                     /gene="gatB"
                     /locus_tag="VQU30_000176"
                     /EC_number="6.3.5.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002946582.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase
                     subunit GatB"
                     /protein_id="HET2446369.1"
                     /translation="MNFETVIGLEVHVELNTNSKIFSPTSAHFGNDQNANTNVIDWSF
                     PGVLPVLNKGVVDAGIKAALALNMDLHKKMHFDRKNYFYPDNPKAYQISQFDEPIGYN
                     GWIEVELEDGTTKKIGIERAHLEEDAGKNTHGTDGYSYVDLNRQGVPLIEIVSEADMR
                     SPEEAYAYLTALKEVIQYAGISDVKMEEGSMRVDANISLRPYGQEKFGTKTELKNLNS
                     FSNVRKGLEYEVQRQAEILRSGGQIRQETRRYDEANKATILMRVKEGAADYRYFPEPD
                     LPLFEISDEWIEEMRTELPEFPKERRARYVSDLGLSDYDASQLTANKVTSDFFEKAVA
                     LGGDAKQVSNWLQGEVAQFLNAEGKTLEQIELTPENLVEMIAIIEDGTISSKIAKKVF
                     VHLAKNGGGAREYVEKAGMVQISDPAILIPIIHQVFADNEAAVADFKSGKRNADKAFT
                     GFLMKATKGQANPQVALKLLAQELAKLKEN"
     gene            20084..20644
                     /gene="efp"
                     /locus_tag="VQU30_000177"
     CDS             20084..20644
                     /gene="efp"
                     /locus_tag="VQU30_000177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000568636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor P"
                     /protein_id="HET2446370.1"
                     /translation="MIEASKLKAGMTFETADGKLIRVLEASHHKPGKGNTIMRMKLRD
                     VRTGSTFDTSYRPEEKFEQAIIETVPAQYLYKMDDTAYFMNTETYDQYEIPVVNVENE
                     LLYILENSDVKIQFYGTEVIGVTVPTTVELTVAETQPSIKGATVTGSGKPATMETGLV
                     VNVPDFIEAGQKLVINTAEGTYVSRA"
     gene            20666..21055
                     /locus_tag="VQU30_000178"
     CDS             20666..21055
                     /locus_tag="VQU30_000178"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517858.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HET2446371.1"
                     /translation="MGIEEQLGEIVIAPRVLEKIIAIATAKVEGVHSFSNRSVSDTLS
                     KLSLGRGVYLKNVDEELTADIYLYLEYGVKVPKVAVAIQKAVKDAVRNMADVELAAIN
                     IHVAGIVPDKTPKPELKDLFDEDFLND"
     gene            21048..21470
                     /gene="nusB"
                     /locus_tag="VQU30_000179"
     CDS             21048..21470
                     /gene="nusB"
                     /locus_tag="VQU30_000179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000203663.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antitermination factor NusB"
                     /protein_id="HET2446372.1"
                     /translation="MTSPLLESRRQLRKCAFQALMSLEFGTNVETACRFAYTHDREDT
                     DVQLPAFLIDLVSGVQAKKEELDKQITQHLKVGWTIERLTLVERNLLRLGVFEITSFD
                     TPQLVAVNEAIELAKDFSDQKSARFINGLLSQFVTEEQ"
     gene            complement(21519..21896)
                     /locus_tag="VQU30_000180"
     CDS             complement(21519..21896)
                     /locus_tag="VQU30_000180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000244505.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HET2446373.1"
                     /translation="MVLSNGQPTFLSTILSFVLLVIIGPVFEETLDRGYFMNTFFPKS
                     KYYLDVILSGLIFGISHLILSHRDPISLLYYSLIGFFFALVYRSTDNLRLTILCHSFF
                     NFLNHAKPIWIFVYNYIYYHFFR"
     gene            complement(22237..22422)
                     /gene="briC"
                     /locus_tag="VQU30_000181"
     CDS             complement(22237..22422)
                     /gene="briC"
                     /locus_tag="VQU30_000181"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000148168.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="biofilm-regulating peptide BriC"
                     /protein_id="HET2446374.1"
                     /translation="MTGTETFTVLSTEDLEQTSGGLAVWEDGYSRWLYYREFAPYMRQ
                     GALNSYIDAWKYGFRTG"
     gene            complement(22581..23348)
                     /locus_tag="VQU30_000182"
     CDS             complement(22581..23348)
                     /locus_tag="VQU30_000182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001017399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase carboxyl transferase
                     subunit alpha"
                     /protein_id="HET2446375.1"
                     /translation="MNIAKIVREAREQSRLTTLDFATGIFDEFIQLHGDRSFRDDGAV
                     VGGIGWLGDQAVTVVGIQKGKSLQDNLKRNFGQPHPEGYRKALRLMKQAEKFGRPVVT
                     FINTAGAYPGVGAEERGQGEAIARNLMEMSDLKVPIIAIIIGEGGSGGALALAVADRV
                     WMLENSIYAILSPEGFASILWKDGTRAMEAAELMKITSHELLEMDVVDKVISEVGLSS
                     KELIKSVKKELQTELARLSQKPLEELLEERYQRFRKY"
     gene            complement(23345..24211)
                     /locus_tag="VQU30_000183"
     CDS             complement(23345..24211)
                     /locus_tag="VQU30_000183"
                     /EC_number="6.4.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001173351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase carboxyltransferase
                     subunit beta"
                     /protein_id="HET2446376.1"
                     /translation="MALFSKKDKYIRINPNRSVREKPQAKPEVPDELFSQCPGCKHTI
                     YQKDLGSERICPHCSYTFRISAQERLALTIDMGTFKELFTGIESKDPLHFPGYQKKLA
                     SMREKTGLHEAVVTGTALIKGQTVALGIMDSNFIMASMGTVVGEKITRLFEYATVEKL
                     PVVLFTASGGARMQEGIMSLMQMAKISAAVKRHSNAGLFYLTILTDPTTGGVTASFAM
                     EGDIILAEPQSLVGFAGRRVIENTVRESLPEDFQKAEFLLEHGFVDAIVKRRDLPDTI
                     ASLVRLHGGSPR"
     gene            complement(24248..25615)
                     /gene="accC"
                     /locus_tag="VQU30_000184"
     CDS             complement(24248..25615)
                     /gene="accC"
                     /locus_tag="VQU30_000184"
                     /EC_number="6.3.4.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000488661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase biotin carboxylase
                     subunit"
                     /protein_id="HET2446377.1"
                     /translation="MFRKILIANRGEIAVRIIRAARELGIATVAVYSTADKEALHTLL
                     ADEAVCIGPGKATESYLNINAVLSAAVLTEAEAIHPGFGFLSENSKFATMCEEVGIKF
                     IGPSGHVMDMMGDKINARAQMIKAGVPVIPGSDGEVHNSEEALIVAEKIGYPVMLKAS
                     AGGGGKGIRKVEKPDDLVSAFETASSEAKANYGNGAMYIERVIYPARHIEVQILGDEH
                     GHVIHLGERDCSLQRNNQKVLEESPSIAIGKTLRHEIGAAAVRAAEFVGYENAGTIEF
                     LLDEASSNFYFMEMNTRVQVEHPVTEFVSGVDIVKEQICIAAGQPLSVKQEDIVLRGH
                     AIECRINAENPAFNFAPSPGKITNLYLPSGGVGLRVDSAVYPGYTIPPYYDSMIAKII
                     VHGENRFDALMKMQRALYELEIEGVQTNADFQLDLISDRNVIAGDYDTSFLMETFLPK
                     YQEKE"
     gene            complement(25627..26049)
                     /gene="fabZ"
                     /locus_tag="VQU30_000185"
     CDS             complement(25627..26049)
                     /gene="fabZ"
                     /locus_tag="VQU30_000185"
                     /EC_number="4.2.1.59"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000565430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-hydroxyacyl-ACP dehydratase FabZ"
                     /protein_id="HET2446378.1"
                     /translation="MIDIQGIKEALPHRYPMLLVDRVLEVSEDTIVAIKNVTINEPFF
                     NGHFPQYPVMPGVLIMEALAQTAGVLELSKPENKGKLVFYAGMDKVKFKKQVVPGDQL
                     VMTATFVKRRGTIAVVEAKAEVDGKLAASGTLTFAIGN"
     gene            complement(26046..26531)
                     /locus_tag="VQU30_000186"
     CDS             complement(26046..26531)
                     /locus_tag="VQU30_000186"
                     /EC_number="6.4.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001052236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase biotin carboxyl carrier
                     protein"
                     /protein_id="HET2446379.1"
                     /translation="MNLNDIKDLMTQFDQSSLREFSYKNGTDELQFSKNEARPVPEVA
                     TQVAPAPVLATPSPVAPTSAPAETVAEEVPAPAEASVASEGNLVESPLVGVVYLAAGP
                     DKPAFVTVGDSVKKGQTLVIIEAMKVMNEIPAPKDGVVTEILVSNEEMVEFGKGLVRI
                     K"
     gene            complement(26534..27769)
                     /gene="fabF"
                     /locus_tag="VQU30_000187"
     CDS             complement(26534..27769)
                     /gene="fabF"
                     /locus_tag="VQU30_000187"
                     /EC_number="2.3.1.179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000774039.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-ketoacyl-ACP synthase II"
                     /protein_id="HET2446380.1"
                     /translation="MKLNRVVVTGYGVTSPIGNTPEEFWNSLATGKIGIGGITKFDHS
                     DFDVHNAAEIQDFPFDKYFVKKDTNRFDNYSLYALYAAQEAVNHANLDVEALNRDRFG
                     VIVASGIGGIKEIEDQVLRLHEKGPKRVKPMTLPKALPNMASGNVAMRFGANGVCKSI
                     NTACSSSNDAIGDAFRSIKFGFQDVMLVGGTEASITPFAIAGFQALTALSTTEDPTRA
                     SIPFDKDRNGFVMGEGSGMLVLESLEHAEKRGATILAEVVGYGNTCDAYHMTSPHPEG
                     QGAIKAIKLALEEAEISPEQVAYVNAHGTSTPANEKGESGAIVAVLGKEVPVSSTKSF
                     TGHLLGAAGAVEAIVTIEAMRHNFVPMTAGTSEVSDYIEANVVYGQGLEKEIPYAISN
                     TFGFGGHNAVLAFKRWENR"
     gene            complement(27791..28522)
                     /gene="fabG"
                     /locus_tag="VQU30_000188"
     CDS             complement(27791..28522)
                     /gene="fabG"
                     /locus_tag="VQU30_000188"
                     /EC_number="1.1.1.100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-oxoacyl-[acyl-carrier-protein] reductase"
                     /protein_id="HET2446381.1"
                     /translation="MKLEHKNIFITGSSRGIGLAIAHKFAQAGANIVLNSRGAISEEL
                     LAEFSNYGIKVVPISGDVSDFADAKRMTDQAIAELGSVDVLVNNAGITQDTLMLKMTE
                     ADFEKVLKVNLTGAFNMTQSVLKPMMKAREGAIINMSSVVGLMGNIGQANYAASKAGL
                     IGFTKSVAREVASRNIRVNVIAPGMIESDMTAILSDKIKEATLAQIPMKEFGQAEQVA
                     DLTVFLAGQDYLTGQVIAIDGGLSM"
     gene            complement(28556..29476)
                     /gene="fabD"
                     /locus_tag="VQU30_000189"
     CDS             complement(28556..29476)
                     /gene="fabD"
                     /locus_tag="VQU30_000189"
                     /EC_number="2.3.1.39"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000167658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ACP S-malonyltransferase"
                     /protein_id="HET2446382.1"
                     /translation="MTKTAFLFAGQGAQYLGMGRDFYDQYPIVKETIDRASQVLGYDL
                     RYLIDTEEDKLNQTRYTQPAILATSVAIYRLLQEKGYQPDMVAGLSLGEYSALVASGA
                     LDFEDAVALVAKRGAYMEEAAPADSGKMVAVLNTPVEVIEEACQKASELGVVTPANYN
                     TPAQIVIAGEVVAVDRAVELLQEAGAKRLIPLKVSGPFHTALLEPASQKLAETLAQVS
                     FSDFTCPLVGNTEAAVMQKEDIAQLLTRQVKEPVRFYESIGVMQEAGISNFIEIGPGK
                     VLSGFVKKIDQTAHLAHVEDQASLVALLEK"
     gene            complement(29469..30443)
                     /gene="fabK"
                     /locus_tag="VQU30_000190"
     CDS             complement(29469..30443)
                     /gene="fabK"
                     /locus_tag="VQU30_000190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002896881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="enoyl-[acyl-carrier-protein] reductase FabK"
                     /protein_id="HET2446383.1"
                     /translation="MKTRITELLKIDYPIFQGGMAWVADGDLAGAVSKAGGLGIIGGG
                     NAPKEVVKANIDKIKSLTDKPFGVNIMLLSPFVEDIVDLVIEEGVKVVTTGAGNPSKY
                     MERFHEAGIIVIPVVPSVALAKRMEKIGADAVIAEGMEAGGHIGKLTTMTLVRQVATA
                     ISIPVIAAGGIADGEGAAAGFMLGAEAVQVGTRFVVAKESNAHPNYKEKILKARDIDT
                     TISAQHFGHAVRAIKNQLTRDFELAEKDAFKQEDPDLEIFEQMGAGALAKAVVHGDVE
                     GGSVMAGQIAGLVSKEETAEEILKDLYYGAAKKIQEEASRWAGVVRND"
     gene            complement(30562..30786)
                     /locus_tag="VQU30_000191"
     CDS             complement(30562..30786)
                     /locus_tag="VQU30_000191"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000257841.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl carrier protein"
                     /protein_id="HET2446384.1"
                     /translation="MAVFEKVQEIIVEELGKDASEVTLESTFDDLDADSLDLFQVISE
                     IEDAFDIQIEAENDLKTVGDLVAYVEEQAK"
     gene            complement(30846..31820)
                     /locus_tag="VQU30_000192"
     CDS             complement(30846..31820)
                     /locus_tag="VQU30_000192"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004262906.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ketoacyl-ACP synthase III"
                     /protein_id="HET2446385.1"
                     /translation="MAFAKISQVAHYVPEQVVTNHDLAQIMDTNDEWISSRTGIRQRH
                     ISRTESTSDLATEVAKKLMAKAGITGEELDFIILATITPDSMMPSTAARVQANIGANK
                     AFAFDLTAACSGFVFALSTAEKFIASGRFQKGLVIGSETLSKAVDWSDRSTAVLFGDG
                     AGGVLLEASEQEHFLAESLNSDGSRSECLTYGHSGLHSPFSDQESADSFLKMDGRTVF
                     DFAIRDVAKSIKQTIDESPIEVTDLDYLLLHQANNRILDKMARKIGVDRAKLPANMME
                     YGNTSAASIPILLSECVEQGLIPLDGSQTVLLSGFGGGLTWGTLILTI"
     gene            complement(31820..32254)
                     /locus_tag="VQU30_000193"
     CDS             complement(31820..32254)
                     /locus_tag="VQU30_000193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520594.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HET2446386.1"
                     /translation="MDYQRINEYLTSIFNNVLVIEEVNLRGSRFKDISIKEMHTIDVI
                     GKAPDVTPSQVSKELMVTLGTVTTSLNNLERKGYIERVRSEQDRRVVHLHLTKKGRLI
                     HRLHKRFHKAMVEKIIDGMSEEEIAVMGKGLTNLYQFLEDLK"
     gene            complement(32348..33133)
                     /locus_tag="VQU30_000194"
     CDS             complement(32348..33133)
                     /locus_tag="VQU30_000194"
                     /EC_number="4.2.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004262908.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="enoyl-CoA hydratase"
                     /protein_id="HET2446387.1"
                     /translation="MEHIIYQLEEDLAILTLNRPEVANGFHIPMCEEILEALTLAEEN
                     PAVHFILINANGKVFSVGGDLVEMKRAVDEDDIPSLTKIAELVNTISYKIKQIAKPVL
                     MEVDGAVAGAAANMAVAADFCLATDKAKFIQAFVGVGLAPDAGGIHLLSRSIGVTRAA
                     QLAMTGEALTAEKALEWGLVYRVSEAEKLEKTREQLLKKLRRASSNSYAAIKKLVWES
                     QFKDWQGYATLELNLQKSLAQTEDFKEGVRAHSERRRPKFTGK"
     gene            33458..34822
                     /locus_tag="VQU30_000195"
     CDS             33458..34822
                     /locus_tag="VQU30_000195"
                     /EC_number="2.7.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004251870.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate kinase"
                     /protein_id="HET2446388.1"
                     /translation="MKVVKFGGSSLASASQLEKVLNIVKSDSERRFVVVSAPGKRNAE
                     DTKVTDALIKYYRDYVAGNDISKSQSWIIDRYAAMVSELGLKPAVLEKISKSIHALAT
                     LPIEENEFLYDTFLAAGENNNAKLIAAYFNQNGIDARYMHPREAGIVVTSEPGHARII
                     PSSYDKIEELTNTNEVLVIPGFFGVTKENQICTFSRGGSDITGSIIAAGVKADLYENF
                     TDVDGIFAAHPGIIHQPHSIPELTYREMRELAYAGFSVLHDEALLPAYRGKIPLVIKN
                     TNNPDHPGTRIVLKHSNDEFPVVGIAGDSGFVSINMSKYLMNREVGFGRKVLQILEEL
                     NIGWEHMPTGIDDLSIILRSRQLTPIKEEEILRQLVQKAKVDHAEIEHDLSIIMIVGE
                     KMKSHIGVTATATRALSENKINIQMMSQGSSEVSIMFVVNKDQEKAAIKALYNAFFGE
                     SKED"
     gene            34825..35196
                     /locus_tag="VQU30_000196"
     CDS             34825..35196
                     /locus_tag="VQU30_000196"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000079352.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF956 family protein"
                     /protein_id="HET2446389.1"
                     /translation="MAQSLNKTVLLSTTGTSYLSIAGKVGKFLVGDQALEFYPDVNVE
                     QFIQIPWSHINQIGANVTGRKISRHFEVFTDKGKFLFASKDSGAILKIAREKLGNDKV
                     VKLPTLIQTISQKFKNLFAKK"
     gene            35410..36684
                     /gene="serS"
                     /locus_tag="VQU30_000197"
     CDS             35410..36684
                     /gene="serS"
                     /locus_tag="VQU30_000197"
                     /EC_number="6.1.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000884256.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine--tRNA ligase"
                     /protein_id="HET2446390.1"
                     /translation="MLDIKRIRTDFEAVAEKLATRGVDAAVLNEMKEIDAKRRNILVK
                     VETLKAERNTVSAEIAQAKRNKENTDDKIAAMQNLSAEVKALDAELAEIDAKLTEFTT
                     TLPNIPADSVPVGTDEDDNVEVRRWGTPREFDFEPKAHWDLGEDLGILDWERGGKVTG
                     ARFLFYKGLGARLERAIYNFMLDEHGKEGYTEVITPYIVNHDSMFGTGQYPKFKEDTF
                     ELSDTNFVLIPTAEVPLTNYYRDEILDGKDLPIYFTAMSPSFRSEAGSAGRDTRGLIR
                     LHQFHKVEMVKFAKPEESYEELEKMTANAENILQKLNLPYRVVALSTGDMGFSAAKTY
                     DLEVWIPAQNNYREISSCSNTEDFQARRAQIRYRDEADGKVKLLHTLNGSGLAVGRTV
                     AAILENYQNEDGSVTIPEALRPYMGGAEVIKP"
     gene            complement(36709..37608)
                     /locus_tag="VQU30_000198"
     CDS             complement(36709..37608)
                     /locus_tag="VQU30_000198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000735961.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TDT family transporter"
                     /protein_id="HET2446391.1"
                     /translation="MKKLPLVFSGCLLGLAGAGNLILDTLPVLSHLFSLTGLVLWIYF
                     LILHLFNWKETKQELTKPPLLSGMATFPMAGMILSTYVFRVFSYLPLVAQGIWWFSFL
                     LDLTLIAGFTIKFACSGRRVHATPSWTVLYVGIAVAALTYPLVGIIEIAYATLSFGFL
                     LTFYLYPLIYSDLKKHPLPLALLGQEGIYCAPFSLLLASLVRVGGTSLPTWVLIVMIL
                     ASQSFFFFVLTRLPNILKQGFQPALSALTFPTIITATSLKMAQGILKLPFLDYLVLAE
                     TIICLTILFFVLGAYLIWLRKKV"
     gene            complement(37718..38266)
                     /locus_tag="VQU30_000199"
     CDS             complement(37718..38266)
                     /locus_tag="VQU30_000199"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000206764.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carboxymuconolactone decarboxylase family
                     protein"
                     /protein_id="HET2446392.1"
                     /translation="MTTFTIHTVESAPAEVKEILETVEKDNNGYIPNLIGLLANAPTV
                     LEAYQIVSSIHRRNSLTPVEREVVQITAAVTNGCAFCVAGHTAFSIKQIQMNDDLIQA
                     LRNRTPIETDPKLDTLAKFTLAVINTKGRVGDEALSEFLEAGYTQQNALDVVFGVSLA
                     ILCNYANNLANTPINPELQPYA"
     gene            complement(38484..39806)
                     /locus_tag="VQU30_000200"
     CDS             complement(38484..39806)
                     /locus_tag="VQU30_000200"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sodium:alanine symporter family protein"
                     /protein_id="HET2446393.1"
                     /translation="MLELLKSIDAFAWGPPLLILLVGTGIYLTMRLGLLQVLRLPKAF
                     QLIFIQDKGHGDVSSFAALCTALASTVGTGNIIGVATAIKVGGPGALFWMWMAAFFGM
                     ATKYAEGLLAIKYRTKDDHGAVAGGPMHYILLGMGEKWRPLAVLFAVAGVLVALLGIG
                     TFTQVNSITESIQNTTTISPAITALVLSVFVAIAVFGGLKSISKVSTTVVPFMALIYI
                     LGTLTVIFFNIGKIPGTIALVFTSAFSPLAAVGGFAGASVRMAIQNGVARGVFSNESG
                     LGSAPIAAAAAKTNEPVEQGLISMTGTFIDTLIICTLTGLTILVTGVWSGDLNGVALT
                     QSAFSTVFSHFGPALLTIFLVLFAFTTILGWNYYGERCFEFLFGARFIWLYRVFFVLM
                     VLLGGFIELDMVWIIADIVNALMALPNLIALLVLSPVVIAETKKYFDK"
     regulatory      complement(39897..39985)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00504"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="glycine riboswitch; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="glycine"
                     /db_xref="RFAM:RF00504"
     gene            complement(40149..42485)
                     /locus_tag="VQU30_000201"
     CDS             complement(40149..42485)
                     /locus_tag="VQU30_000201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001035046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease MutS2"
                     /protein_id="HET2446394.1"
                     /translation="MNKKILETLEFDKVKALFDPHLLTEQGLEQLRQLAPTAKADKIK
                     QAFAEMKEMQALFVEQPHFTILSTKEIAGVCKRLEMGADLNIEEFLLLKRVLLASREL
                     QSFYANLENVSLEELALWFEKLHDFPQLQGNLQAFNDAGFIENFASEELARIRRKIHD
                     SESQVRDVLQDLLKQKAQMLTEGIVASRNGRQVLPVKNTYRNKIAGVVHDISASGNTV
                     YIEPREVVKLSEEIASLRADERYEMLRILQEISERVRPHAAEIANDAWIIGHLDLIRA
                     KVRFIQERQAVVPQLSENQEIQLLHVCHPLVKNAVANDVHFGQDLTAIVITGPNTGGK
                     TIMLKTLGLTQVMAQSGLPILADKGSRVGIFEEIFADIGDEQSIEQSLSTFSSHMTNI
                     VDILGKVNQHSLLLLDELGAGTDPQEGAALAMAILEDLRLRQIKTMATTHYPELKAYG
                     IETAFVQNASMEFDTATLRPTYRFMQGVPGRSNAFEIAKRLGLSEVIVGDASQQIDQD
                     NDVNRIIEQLEEQTLESRKRLDNIREVEQENLKMNRALKKLYNELNREKETELNKARE
                     QAAEIVDMALSESDQILKNLHSKSQLKPHEIIEAKAKLKKLAPEKVDLSKNKVLQKAK
                     KKRAPKVGDDIVVLSYGQRGTLTSQLKDGRWEAQVGLIKMTLEEKEFDLVQAQQEKPV
                     KKKQVNVVKRTSGRGPQARLDLRGKRYEEAMNELDTFIDQALLNNMAQVDIIHGIGTG
                     VIREGVTKYLQRNKHVKSFGYAPQNAGGSGATIVTFKG"
     gene            complement(42589..43137)
                     /locus_tag="VQU30_000202"
     CDS             complement(42589..43137)
                     /locus_tag="VQU30_000202"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000622948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CvpA family protein"
                     /protein_id="HET2446395.1"
                     /translation="MISFLLLLVLVWGFYIGYRRGLLLQVYYLISAMASAFMAGQFYK
                     GLGEQFHLLLPYANSQEGQGTFFFPSDQLFQLDKVFYAGIGYLLVFGIFYSIGRLLGL
                     LLHLIPSKKLGGKLFQVSAGILSMLVTLFVLQMALTILATIPMAVIQNPLEKSIVAKH
                     IIQSIPITTSWLKQIWVTNLIG"
     gene            complement(43134..43436)
                     /gene="zapA"
                     /locus_tag="VQU30_000203"
     CDS             complement(43134..43436)
                     /gene="zapA"
                     /locus_tag="VQU30_000203"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006150060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein ZapA"
                     /protein_id="HET2446396.1"
                     /translation="MANLNRFKFTFGKKSLTLTSEHDNLFMEEIAKVATEKYQAIKEQ
                     MPSADDETIALLLAVNCLSTQLSREIEFDDKEQELEELRHKLVTCKQEQSKIEDSL"
     gene            43523..44404
                     /locus_tag="VQU30_000204"
     CDS             43523..44404
                     /locus_tag="VQU30_000204"
                     /EC_number="3.1.26.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000146880.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease HIII"
                     /protein_id="HET2446397.1"
                     /translation="MASITLTPSEKDIQAFLEHYQTSLAPSKNPYIRYFLKLPQATVS
                     IYTSGKILLQGEGAEKYASFFGYQLVEENRGQNLPLIGTDEVGNGSYFGGLAVVAAFV
                     TSDQHDFLRKLGVGDSKTLTDQKIRQIAPILKEKIQHQALLLSPSKYNEVIGDRYNAV
                     SVKVALHNQAIYLLLQKGVQPEKIVIDAFTSAKNYDKYLAQEANRFSNPISLEEKAEG
                     KYLSVAVSSVIARDLFLENLENLGRELGYQLPSGAGTASDKVASQILQAYGMQGLSFC
                     AKLHFKNTEKAKKRLER"
     gene            44408..45022
                     /gene="lepB"
                     /locus_tag="VQU30_000205"
     CDS             44408..45022
                     /gene="lepB"
                     /locus_tag="VQU30_000205"
                     /EC_number="3.4.21.89"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001048155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase I"
                     /protein_id="HET2446398.1"
                     /translation="MNSFKNFLKEWGLFLLILSLLALSRIFFWSNVRVEGHSMDPTLA
                     DGEILFVVKHLPIDRFDIVVAHEEDGNKDIVKRVIGMPGDTIRYENDKLYINDKETDE
                     PYLADYIKRFKDDKLQSTYSGKGFEGNKGTFFRSIAQKAQAFTVDVNYNTNFSFTVPE
                     GEYLLLGDDRLVSSDSRHVGTFKAKDITGEAKFRFWPITRIGTF"
     gene            45081..45224
                     /locus_tag="VQU30_000206"
     CDS             45081..45224
                     /locus_tag="VQU30_000206"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="chlorohydrolase"
                     /protein_id="HET2446399.1"
                     /translation="MFIDKYSTKIKEQTRKLAVGCLKQCFEVVDRTDEVSSKYCFEVA
                     DGS"
     gene            45301..47667
                     /locus_tag="VQU30_000207"
     CDS             45301..47667
                     /locus_tag="VQU30_000207"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000454449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent RecD-like DNA helicase"
                     /protein_id="HET2446400.1"
                     /translation="MEVYFSGTIERIIFENPSNFYRILLLEIDDTDAEDFDDFEIIVT
                     GTMADVIEGEDYTFWGQIVQHSKYGEQLQISRYDRAKPTSKGLVKYFSSSHFKGIGLK
                     TAQKIVDTYGENTIDEILQHPEKLEGIAGLSAKNREAFVSTLRLNYGTEMVLSKLANY
                     GIPNKLAFQIQDFYKEETLDVVENYPYQLVEDIKGLGFTIADQLAEELGIESQAPERF
                     RAGLVHSLFQACMETGDTYVEARDLLEQTLTLLESSRPVELDPSQVAQELSYLIEEDK
                     VQQIDTKIFDNSLFFAEEGIRSHLVRILEKGKQKSHDLETIQKHITTIEEELGIEYDN
                     IQKQAICDAIQNKVFILTGGPGTGKTTVINGIIAVYALLEGLDFRKKSNLPILLAAPT
                     GRAARRMNELTGLPSATIHRHLGMTGDDDTSHLEDYLDADFIIVDEFSMVDTWLANQL
                     FSNISSNSKILIVGDSDQLPSVSPGQVLADLLHIPLIPQTHLEKIYRQSKESTIVTLA
                     SQIRQGILPADFTQKKADRSYFEIASGHIPATIEKILGAALRNGIPARDIQVLAPMYR
                     GTAGIDAINQLMQDLLNPPQKDQLSFEAPQCHYRKGDKVIHLVNDAEINVFNGDLGAI
                     TDLIPGKYTESKQDEIVIDFDGNEVSYPRNEWYKIRLAYAMSIHKSQGSEFPVVILPI
                     TSASRRMLERNLIYTAITRAKSKLILLGELQAFDYATQHIGTARKTYLIERFSDLLEN
                     VEEKQQAVSETVTSSASEQSYILTEENWDSIPAMIGITDTDLKEIFGK"
     gene            complement(47715..48998)
                     /locus_tag="VQU30_000208"
     CDS             complement(47715..48998)
                     /locus_tag="VQU30_000208"
                     /EC_number="5.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trigger factor"
                     /protein_id="HET2446401.1"
                     /translation="MSVSFENKETNRGVLTFTISQDQIKPELDRVFKSVKKSLNVPGF
                     RKGHLPRPIFDKKFGEESLYQDVMNALLPNAYEAAVKEAGLEVVAQPKIDVTSMEKGQ
                     DWVIAAEVVTKPEVKLGDYKNLEVSVDVEKEVTDADVEERIERERNNLAELVIKEAAA
                     EDGDTVVIDFVGSIDGVEFDGGKGENFSLGLGSGQFIPGFEDQLVGHSAGETVDVIVT
                     FPEDYQAEDLAGKEAKFVTTIHEVKAKEVPALDDELAKDIDEEVETLADLKEKYRKEL
                     AAAKEEAYKDAVEGAAIDTAVENAEIVELPEEMIHEEVHRSVNEFLGNLQRQGINPDM
                     YFQITGTTQEDLHNQYQAEAESRTKTNLVIEAVAKAEGFDASEEEIQKEVEQLAADYN
                     MEVAQVQNLLSADMLKHDITIKKAVELITSTATVK"
     gene            complement(49192..49551)
                     /locus_tag="VQU30_000209"
     CDS             complement(49192..49551)
                     /locus_tag="VQU30_000209"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397741.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HET2446402.1"
                     /translation="MDSPKSLASYRVIGISDRVLEILKEYLLLEEGDYIFTNNGSPLM
                     ITCFNYFLKNRFRKSEIKKDDFVLTAHVFRYSHISLLAELEVPITAIMDRVDYTNETK
                     ILSVYTHVTEKMKSNIT"
     gene            complement(49850..50479)
                     /locus_tag="VQU30_000210"
     CDS             complement(49850..50479)
                     /locus_tag="VQU30_000210"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844741.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine protease"
                     /protein_id="HET2446403.1"
                     /translation="MVLSKYYGVADGMNVEGRGSANFIKDNVLITAAHNYYRHDYGKE
                     ADDIYVLPTVSPSQEPFGKIKVKEVRYLKEFRNLNSKDAREYDLALLILEEPIGAKLG
                     TLGLPTSQKNLTGITVTITGYPSYNFKVHQMYTDKKQVLSDDGMFLDYQVDTLEGSSG
                     STVYDASHRVVGVHTLGDGANQINSAVKLNERNLPFIYSVLKGYSLEGW"
     gene            complement(50524..50763)
                     /locus_tag="VQU30_000211"
     CDS             complement(50524..50763)
                     /locus_tag="VQU30_000211"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000754500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2446404.1"
                     /translation="MKKTVYKKLGISIIASTLLASQLSTVSALSVISSTGEEYEVSET
                     LEKGPGSNDSSLSEISPTYGSYYQKQSEVLSVMMI"
     gene            complement(50913..51179)
                     /locus_tag="VQU30_000212"
                     /pseudo
     CDS             complement(50913..51179)
                     /locus_tag="VQU30_000212"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000060522.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DNA alkylation repair protein"
     gene            complement(51204..51512)
                     /locus_tag="VQU30_000213"
     CDS             complement(51204..51512)
                     /locus_tag="VQU30_000213"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004250000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA alkylation repair protein"
                     /protein_id="HET2446405.1"
                     /translation="MDWDFADTCWEKEPRKYQYVAANYLKAMQSYLKETDLPKLEQLV
                     VTKSWWDTVDILDRVVGSLVYEHPELEEIILILFENLFKPRQLYLQPQNSVLRLQIAS
                     "
     gene            complement(51437..51679)
                     /locus_tag="VQU30_000214"
     CDS             complement(51437..51679)
                     /locus_tag="VQU30_000214"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812384.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA alkylation repair protein"
                     /protein_id="HET2446406.1"
                     /translation="MSLADLLEELEAAKDSKKARPMEAYMRHQFSFLGIAVPERNKLY
                     KNIYQKRKKQRLSIGILQTLAGKRSLENTNMWLLTI"
     gene            complement(51680..52312)
                     /locus_tag="VQU30_000215"
     CDS             complement(51680..52312)
                     /locus_tag="VQU30_000215"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000698412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HET2446407.1"
                     /translation="MKILLVDDHEMVRLGLKSYFDLQDDVEVVGEASNGSQGIDLALE
                     LRPDVIVMDIVMPEMNGIDATLAILKEWPEAKILIVTSYLDNEKIMPVLDAGAKGYML
                     KTSSADELLHAVSKVAAGELAIEQEVSKKVEYHRNHMELHEELTARERDVLQLIAKGY
                     ENQRIADDLFISLKTVKTHVSNILAKLEVSDRTQAAVYAFQHHLVGQEEF"
     gene            complement(52326..53321)
                     /locus_tag="VQU30_000216"
     CDS             complement(52326..53321)
                     /locus_tag="VQU30_000216"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000743650.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HET2446408.1"
                     /translation="MKKQAYVIIALTSFLFVFFFSHSLLEILDFDWSIFLYDVEKTEK
                     FVFLLLVFSMSMTCLLALFWRGIEELSLRKMQANLKRLLAGQEVVQVVDPDLDASFKS
                     LSGKLNLLTEALQKAENHSLDQEEEIIEKERKRIARDLHDTVSQELFAAHIILSGISQ
                     QALKLDREKMQTQLQSVTAILETAQKDLRVLLLHLRPVELEQKSLIEGIQILLKELED
                     KSDLRVSLKQNMTKLPKKIEEHIFRILQELISNTLRHAQASCLDVYLYQTDVELQLKV
                     VDNGIGFRLGSLDDLSYGLRNIKERVEDMAGTVQLLTAPKQGLAVDIRIPLLDKE"
     gene            complement(53318..54016)
                     /locus_tag="VQU30_000217"
     CDS             complement(53318..54016)
                     /locus_tag="VQU30_000217"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001224647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-active antibiotics response protein"
                     /protein_id="HET2446409.1"
                     /translation="MRKFKIFLFIEACLLTGALILMVSEHFSRFLLILFLFLLLIRYY
                     TGKEGNNLLLVAATILFFFIVMLNPFVILAIFVAVIYSLFLLYPMMNQEKEQTNLVFE
                     EVVTVKKEKNRWFGNLHHFSSYQTCQFDDINLFRFMGKDTIHLERVILTNHDNVIILR
                     KMVGTTKIIVPVDVEVSLSVNCLYGDLTFFNQPKRALRNEHYHQETKDYLKSNKSVKI
                     FLTTMIGDVEVVRG"
     gene            complement(54094..55104)
                     /locus_tag="VQU30_000218"
     CDS             complement(54094..55104)
                     /locus_tag="VQU30_000218"
                     /EC_number="5.3.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000210649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 2 isopentenyl-diphosphate Delta-isomerase"
                     /protein_id="HET2446410.1"
                     /translation="MTTNRKDEHILYALEQKSSYNSFDEVELIHSSLPLYNLDEIDLS
                     TEFAGRKWDFPFYINAMTGGSNKGREINQKLAQVAESCGILFVTGSYSAALKNPTDDS
                     FSVKSSHPNLLLGTNIGLDKPVELGLQTVEEMNPVLLQVHVNVMQELLMPEGERKFRS
                     WQSHLADYSKQIPVPIVLKEVGFGMDAKTIERAYEFGVRTVDLSGRGGTSFAYIENRR
                     SGQRDYLNQWGQSTMQALLNAQEWKDKVELLVSGGVRNPLDMIKCLVFGAKAVGLSRT
                     VLELVETYTVEEVIGIVQGWKADLRLIMCSLNCATIADLQKVDYLLYGKLKEAKDQMK
                     KA"
     gene            complement(55088..56095)
                     /locus_tag="VQU30_000219"
     CDS             complement(55088..56095)
                     /locus_tag="VQU30_000219"
                     /EC_number="2.7.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000562378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphomevalonate kinase"
                     /protein_id="HET2446411.1"
                     /translation="MIAVKTCGKLYWAGEYAILEPGQLALIKDIPIYMRAEIAFSDSY
                     RIYSDMFDFAVDLTPNPDYSLIQETIALMGDFLAVRGQNLRSFSLEICGKMEREGKKF
                     GLGSSGSVVVLVVKALLALYDVSVDQELLFKLTSAVLLKRGDNGSMGDLACIVAEDLV
                     LYQSFDRQKVAAWLEEENLATVLERDWGFSISQVKPTLECDFLVGWTKEVAVSSHMVQ
                     QIKQNINQNFLSSSKETVVSLVEALEQGKSEKIIEQVEVASKLLEGLSTDIYTPLLRQ
                     LKEASQDLQAVAKSSGAGGGDCGIALSFDAQSTKTLKNRWADLGIELLYQERIGHDDK
                     S"
     gene            complement(56082..57035)
                     /gene="mvaD"
                     /locus_tag="VQU30_000220"
     CDS             complement(56082..57035)
                     /gene="mvaD"
                     /locus_tag="VQU30_000220"
                     /EC_number="4.1.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000373478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diphosphomevalonate decarboxylase"
                     /protein_id="HET2446412.1"
                     /translation="MDREPVTVRSYANIAIIKYWGKKKEKEMVPATSSISLTLENMYT
                     ETTLSPLPANVIADEFYINGQLQNEVEHAKMSKIIDRYRPAGEGFVRIDTQNNMPTAA
                     GLSSSSSGLSALVKACNAYFKLGLDRSQLAQEAKFASGSSSRSFYGPLGAWDKDSGEI
                     YSVETDLKLAMIMLVLEDKKKPISSRDGMKLCVETSTTFDDWVRQSEKDYQDMLIYLK
                     ENDFAKIGELTEKNALAMHATTKTASPAFSYLTDASYEAMDFVRQLREKGEACYFTMD
                     AGPNVKVFCQEKDLEHLSEIFGQRYRLIVSKTKDLSQDDCC"
     gene            complement(57017..57895)
                     /gene="mvk"
                     /locus_tag="VQU30_000221"
     CDS             complement(57017..57895)
                     /gene="mvk"
                     /locus_tag="VQU30_000221"
                     /EC_number="2.7.1.36"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000163319.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mevalonate kinase"
                     /protein_id="HET2446413.1"
                     /translation="MTKKVGVGQAHSKIILIGEHAVVYGYPAISLPLLEVEVTCKVVP
                     AESPWRLYEEDTLSMAVYASLEYLDITEACIRCEIDSAIPEKRGMGSSAAISIAAIRA
                     VFDYYQADLPHDVLEILVNRAEMIAHMNPSGLDAKTCLSDQPIRFIKNVGFTELEMDL
                     SAYLVIADTGVYGHTREAIQVVQNKGKDALPFLHALGELTQQAEVAISQKDAEGLGQI
                     LSQAHLHLKEIGVSSPEADFLVETTLSHGALGAKMSGGGLGGCIIALVTNLTHAQELA
                     ERLEEKGAVQTWIESL"
     gene            complement(58017..58346)
                     /locus_tag="VQU30_000222"
     CDS             complement(58017..58346)
                     /locus_tag="VQU30_000222"
                     /inference="COORDINATES: protein motif:HMM:NF024736.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HET2446414.1"
                     /translation="MTRKAYDTDLNDQEWAKIEPYFSKHRTYKWPKRVLVNETLYVTK
                     TGCQWRMIPHDFPLYLTVWSFFRRSMTTGWFQVNGRWYYAYSSGALAVNTTVDGYSVN
                     YNGEWVQ"
     gene            59008..59344
                     /locus_tag="VQU30_000223"
                     /pseudo
     CDS             59008..59344
                     /locus_tag="VQU30_000223"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001811282.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="lantibiotic-modifying protein"
     gene            59244..59831
                     /locus_tag="VQU30_000224"
     CDS             59244..59831
                     /locus_tag="VQU30_000224"
                     /inference="COORDINATES: protein motif:HMM:NF017000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2446415.1"
                     /translation="MTILLKLSSTIVYGEIYHYFLQRDTAKESILDYSFAHGYCEIAY
                     ALFAYSKVLEPSMFYNDLHTFHAELKKLLEKVTSNTENLGNLQLSWCEGISGIILYLC
                     MYDCDGNKDIISKYQEFVFNHHLKMMTGYCHGITSLLQTTVYNQNKLLMKKIQQVILA
                     CSERDDHGLLMFQGDSGKADLFDFGIGSRGYIGVY"
     gene            59874..61106
                     /locus_tag="VQU30_000225"
     CDS             59874..61106
                     /locus_tag="VQU30_000225"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000765682.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HET2446416.1"
                     /translation="MKLFWTNNIYRQLLLNSCFSSFGDSIFYLAIINYVAQYNFAPLA
                     ILLISISEMVPLLSQLFLGILGDFQENRVKHALCIAKIKILLYAILTVFLVLSPFSLV
                     SVIMIVIINLISDTLSYLSAYMMNALYISVIKDDLHDAMGFRQSLMRVVHIVANLAGA
                     FLINVISIQTISLINTLTFVIAFLGLYVIRHTLYEVEKRIEMSHTALSFKKYFQHLKQ
                     SLAVLLRLKDTVILLFLTTSMIAILDVSPRLIALRFIQQTLAQLSIGQLFALLSIIMS
                     CGAILGNMTSSNLFKNIRFTHLLVFCEISLLALITSILCQAYIVIFVTSFISSTIIGI
                     LSPRLQAAVFAHIPSDKMGTVGSALSTVDILAPSLLSLLALSIASGVSVQLALIFLYL
                     ILIALIFCQWLVKFNTHN"
     gene            complement(61224..62180)
                     /gene="cbpC"
                     /locus_tag="VQU30_000226"
     CDS             complement(61224..62180)
                     /gene="cbpC"
                     /locus_tag="VQU30_000226"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000771060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choline-binding protein CbpC"
                     /protein_id="HET2446417.1"
                     /translation="MKLLKKMMQVLLAVFFFGLLATNTVFANTTGGRFVDKDNRKYYV
                     KDDHKAIYWHKIDGKTYYFGDIGEMVVGWQYLEIPGTGYRDDLFDNRPVFEIGLQEKW
                     YYFGQDGALLEQTDKQVLEAKTSENTGKVYGEQYPLSAEKRTYYFDNNYAVKTGWIYE
                     DGNWYYLNKLGNFGDDSYNPLPIGEVAKGWTQDFHVTIDIDRSKPAPWYYLRSSGAMA
                     TGWYQEGTTWYYLDQPNGDMKTGWQNLGNKWYYLRSSGAMATGWYQDGSTWYYLNAGN
                     GDMKTGWFQVNGNWYYAYSSGALAVNTTVDGYSVNYNGEWVR"
     gene            complement(62278..62967)
                     /locus_tag="VQU30_000227"
     CDS             complement(62278..62967)
                     /locus_tag="VQU30_000227"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000518023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HET2446418.1"
                     /translation="MGKRILLLEKERNLAHFLSLELQKEQYRVDLVEEGQKALSMALQ
                     TDYDLILLNVNLGDMMAQDFAEKLSRTKPASVIMILDHWEDLQEELEVVQRFAVSYIY
                     KPVFIENLVARISAIFRGRDFIDQHCSLMKVPRTYRNLRIDVEHHTVYRGEEMIALTR
                     REYDLLATLMGSKKVLTREQLLESVWKYESATETNIVDVYIRYLRSKLDVKGQKSYIK
                     TVRGVGYTMQE"
     gene            complement(62979..64403)
                     /gene="gndA"
                     /locus_tag="VQU30_000228"
     CDS             complement(62979..64403)
                     /gene="gndA"
                     /locus_tag="VQU30_000228"
                     /EC_number="1.1.1.44"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004185725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-dependent phosphogluconate dehydrogenase"
                     /protein_id="HET2446419.1"
                     /translation="MTKANFGVVGMAVMGRNLALNIESRGYTVAIYNRSKEKTEDVIA
                     CHPEKNFVPSYDVESFVNSIEKPRRIMLMVQAGPGTDATIQALLPHLDKGDILIDGGN
                     TFYKDTIRRNEELANSGINFIGTGVSGGEKGALEGPSIMPGGQKEAYELVSDVLEEIS
                     AKAPEDGKPCVTYIGPDGAGHYVKMVHNGIEYGDMQLIAESYDLMQHLLGLSAEDMAE
                     IFTEWNKGELDSYLIEITADILSRKDDEDQDGPIVDYILDAAGNKGTGKWTSQSSLDL
                     GVPLSLITESVFARYISTYKEERVHASKVLPKPAAFNFEGDKAELIEKIRQALYFSKI
                     ISYAQGFAQLRVASKENNWNLPFADIASIWRDGCIIRSRFLQKITDAYNRDADLANLL
                     LDEYFLDVTAKYQQAVRDIVALAVQAGVPVPTFSAAITYFDSYRSADLPANLIQAQRD
                     YFGAHTYQRKDKEGTFHYSWYDEK"
     gene            complement(64479..65873)
                     /gene="mapZ"
                     /locus_tag="VQU30_000229"
     CDS             complement(64479..65873)
                     /gene="mapZ"
                     /locus_tag="VQU30_000229"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000039255.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mid-cell-anchored protein MapZ"
                     /protein_id="HET2446420.1"
                     /translation="MSKKRRNRHKKEGQEPQFDFDEAKELTVGQAIRKNEEVEAGVLP
                     EDSILDKYVKQHRDEIEADKFATRQYKKEEFVETQSLDDLIQEMREAVEKSEASSEEV
                     PSSEDILLPLPLDDEEQGLDPLLLDDENPTEMTEEVEEEQNLSRLDQEDSEKKSKKGF
                     ILTVLALVSVIICVSAYYVYRQVARSTKEIETSQSTTANQSDVDDFNTLYDAFYTNSN
                     KTALKNSQFDKLSQLKTLLDKLEGSREHTLAKSKYDSLVTQIKAIQDVNAQFEKPAIV
                     DGVLDTNAKAKSDAKFTDIKTGNTELDKVLDKAISLGKSQQTSTSSSSSSQTSSSSSS
                     QASSNTTSEPKPSSSNETRSSRSEVNMGLSSAGVAVQRSASRVAYNQSAIDDSNNSAW
                     DFADGVLEQILATSRSRGYITGDQYILERVNIVNGNGYYNLYKPDGTYLFTLNCKTGY
                     FVGNGAGHADDLDY"
     gene            complement(65886..67043)
                     /locus_tag="VQU30_000230"
     CDS             complement(65886..67043)
                     /locus_tag="VQU30_000230"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000711388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent RNA methyltransferase"
                     /protein_id="HET2446421.1"
                     /translation="MKKEFNLIATVAAGLEAVVGREVRELGYDCQVENGRVRFQGDVR
                     AIIETNLWLRAADRIKIIVGTFPAKTFEELFQGVFALDWENYLPLGARLPISKAKCVK
                     SKLHNEPSVQAISKKAVVKKLQKHYARPEGVPLMENGPEFKIEVSILKDVATVMIDTT
                     GSSLFKRGYRTEKGGAPIKENMAAAILQLSNWYPDKPLIDPTCGSGTFCIEAVMIARK
                     MAPGLRRSFAFEEWNWISDRLIQEVRTEAAKKVERKLELDIMGCDIDARMVEIAKANA
                     QAAGVAGDITFKQMRVQDLRSDKINGVIISNPPYGERLSDDAGVTKLYAEMGQVFAPL
                     KTWSKFILTSDEAFESKYGSQADKKRKLYNGTLKVDLYQYFGQRVKRQEVK"
     gene            complement(67128..67508)
                     /gene="rnpB"
                     /locus_tag="VQU30_000231"
     ncRNA           complement(67128..67508)
                     /ncRNA_class="RNase_P_RNA"
                     /gene="rnpB"
                     /locus_tag="VQU30_000231"
                     /product="RNase P RNA component class B"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00011"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00011"
     gene            complement(67529..67858)
                     /gene="gpsB"
                     /locus_tag="VQU30_000232"
     CDS             complement(67529..67858)
                     /gene="gpsB"
                     /locus_tag="VQU30_000232"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000146522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division regulator GpsB"
                     /protein_id="HET2446422.1"
                     /translation="MASIIFSAKDIFEQEFGREVRGYNKVEVDEFLDDVIKDYETYAA
                     LVKSLRQEIADLKEELTRKPKPSPVQAEPLEAAITSSMTNFDILKRLNRLEKEVFGKQ
                     ILDNSDF"
     gene            complement(67928..68455)
                     /locus_tag="VQU30_000233"
     CDS             complement(67928..68455)
                     /locus_tag="VQU30_000233"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000179549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1273 domain-containing protein"
                     /protein_id="HET2446423.1"
                     /translation="MATALVLGYSAFDLGLFSDKDPRLKLIKKAIRKDLEAMAADGVS
                     WLVFTGSLGFEYWVLEVAQEMKTEYGFQLATIFAFETHGENWNEGNQMKLSRFKQVDF
                     VKYAYPRYEHKGQLRDYQQFLLENTTSSYLFYDEENETKLAYFYQKMKNQEDYFIKRL
                     TFDQLNELAENFSEN"
     gene            68521..69117
                     /gene="recU"
                     /locus_tag="VQU30_000234"
     CDS             68521..69117
                     /gene="recU"
                     /locus_tag="VQU30_000234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000248773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction resolvase RecU"
                     /protein_id="HET2446424.1"
                     /translation="MINYPHKVSSQKRQTSLSQPKNFANRGMSFEKMINATNDYYLSQ
                     GLAVIHKKPTPIQIVQVDYPQRSRAKIVEAYFRQASTTDYSGVYNGYYIDFEVKETKQ
                     KRAIPMKNFHPHQIQHMEQVLAQQGICFVLLHFSSQQETYLLPAFDLIRFYHQDKGQK
                     SMPLEYIREYGYEIKAGAFPQIPYLNVIKEHLLGGKTR"
     gene            69114..71273
                     /locus_tag="VQU30_000235"
     CDS             69114..71273
                     /locus_tag="VQU30_000235"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001040003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein 1A"
                     /protein_id="HET2446425.1"
                     /translation="MNKPTILRLIKYLSISFLSLVIAAIVLGGGVFFYYVSKAPSLSE
                     SKLVATTSSKIYDNKNQLIADLGSERRVNAQANDIPTDLVKAIVSIEDHRFFDHRGID
                     TIRILGAFLRNLQSNSLQGGSTLTQQLIKLTYFSTSTSDQTISRKAQEAWLAIQLEQK
                     ATKQEILTYYINKVYMSNGNYGMQTAAQNYYGKDLNNLSLPQLALLAGMPQAPNQYDP
                     YSHPEAAQDRRNLVLSEMKNQGYISAEQYEKAVNTPITDGLQSLKSASNYPAYMDNYL
                     KEVINQVEEETGYNLLTTGMDVYTNVDQEAQKHLWDIYNTDEYVAYPDDELQVASTIV
                     DVSNGKVIAQLGARHQSSNVSFGINQAVETNRDWGSTMKPITDYAPALEYGIYDSTAT
                     IVHDEPYNYPGTNTPVYNWDRGYFGNITLQYALQQSRNVPAVETLNKVGLNRAKTFLN
                     GLGIDYPSIHYSNAISSNTTESDKKYGASSEKMAAAYAAFANGGTYYKPMYIHKVVFS
                     DGSEKEFSNVGTRAMKETTAYMMTDMMKTVLTYGTGRNAYLAWLPQAGKTGTSNYTDE
                     EIENHIKTSQFVAPDELFAGYTRKYSMAVWTGYSNRLTPLVGNGLTVAAKVYRSMMTY
                     LSEGSNPEDWNIPEGLYRNGEFVFKNGARSTWSSPAPQQPPSTESSSSSSDSSTSQSS
                     STTPSTNNSTTTNPNNNTQQSNTTPDQQNQNPQPAQP"
     gene            complement(71440..76743)
                     /locus_tag="VQU30_000236"
     CDS             complement(71440..76743)
                     /locus_tag="VQU30_000236"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001032503.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YSIRK signal domain/LPXTG anchor domain surface
                     protein"
                     /protein_id="HET2446426.1"
                     /translation="MNKGLFEKRCKYSIRKFSLGVASVMIGAAFFGTSPVLADSVQSG
                     STANLPADLATALATANENDGRDFEAPKVGEDQGSPEVTDGPKTEEELLALEKEKPAE
                     EKPKEDKPAAAKPETPKTVTPEWQTVEKKEQQGTVTIREEKGVRYNQLFSTAQNDNAG
                     KPALFEKKGLTVDANGNATVDLTFKEDSEKGKSRFGVFLKFKDTNNNVFVGYDKDGWF
                     WEYKTPGNSTWYKGNRVVAPEPGSVNRLSITLKSDGQLNASNNDVNLFDTVTLPGAVN
                     DNLKNEKKILLKAGTYGNDRTVVSVKTDNQEGVKADDTPAQKETGPVVDDSKVTYDTI
                     QSKVLKAVIDQAFPRVKEYSLNGHTLPGQVQQFNQVFINNHRITPEVTYKKINETTAE
                     YLMKLRDDAHLINAEMTVRLQVVDNQLHFDVTKIVNHNQVTPGQKIDDERKLLSSISF
                     LGNALVSVSSDQTGAKFDGATMSNNTHVSGDDHIDVTNPMKDLAKGYMYGFVSTDKLA
                     AGVWSNSQNSYGGGSNDWTRLTAYKETVGNANYVGIHSSEWQWEKAYKGIVFPEYTKE
                     LPSAKVVITEDANADKKVDWQDGAIAYRSIMNNPQGWEKVKDITAYRIAMNFGSQAQN
                     PFLMTLDGIKKINLHTDGLGQGVFLKGYGSEGHDSGHLNYADIGKRIGGVEDFKTLIE
                     KAKKYGAHLGIHVNASETYPESKYFNEKILRKNPDGSYSYGWNWLDQGINIDAAYDLA
                     HGRLARWEDLKKKLGDGLDFIYVDVWGNGQSGDNGAWATHVLAKEINKQGWRFAIEWG
                     HGGEYDSTFHHWAADLTYGGYTNKGINSAITRFIRNHQKDAWVGDYRSYGGAANYPLL
                     GGYSMKDFEGWQGRSDYNGYVTNLFAHDVMTKYFQHFTVSKWENGTPVTMTDNGSTYK
                     WTPEMRVELVDADNNKVVVTRKSNDVNSPQYRERTVTLNGRVIQDGSAYLTPWNWDAN
                     GKKLSTDKEKMYYFNTQAGATTWTLPSDWAKSKVYLYKLTDQGKTEEQELTVKDGKIT
                     LDLLANQPYVLYRSKQTNPEMSWSEGMHIYDQGFNSGTLKHWTISGDASKAEIVKSQG
                     ANDMLRIQGNKEKVSLTQKLTGLKPNTKYAVYVGVDNRSNAKASITVNTGEKEVTTYT
                     NKSLALNYVKAYAHNTRRNNATVNDTSYFQNMYAFFTTGSDVSNVTLTLSREAGDQAT
                     YFDEIRTFENNSSMYGDKHDTGQGTFKQDFENVAQGIFPFVVGGVEGVEDNRTHLSEK
                     HDPYTQRGWNGKKVDDVIEGNWSLKTNGLVSRRNLVYQTIPQNFRFEAGKTYRVTFEY
                     EAGSDNTYAFVVGKGEFQSGRRGTQASNLEMHELPNTWTDSKKAKKATFLVTGAETGD
                     TWVGIYSTGNASNTRGDSGGNANFRGYNDFMMDNLQIEEITLTGKMLTENALKNYLPT
                     VAMTNYTKESMDALKEAVFNLSQADDDISVEEARAEIAKIEALKNALVQKKTALVADD
                     FASLTAPAQAQEGLANAFDGNLSSLWHTSWNGGDVGKPATMVLKEPTEITGLRYVPRG
                     SGSNGNLRDVKLVVTDESGKEHTFTATDWPDNNKPKDIDFGKTIKAKKIVLTGTKTYG
                     DGGDKYQSAAELIFTRPQVAETPLDLSGYEAALAKAQKLTDKDNQEEVASVQASMKYA
                     TDNHLLTERMVEYFADYLNQLKDSATKPDAPTVEKPEFKLSSLVSDQGKTPDYKQEIA
                     RPETPEQILPATGESQSDTALFLASVSLALSALFVVKTKKD"
     gene            complement(77044..79026)
                     /locus_tag="VQU30_000237"
     CDS             complement(77044..79026)
                     /locus_tag="VQU30_000237"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide ABC transporter substrate-binding
                     protein"
                     /protein_id="HET2446427.1"
                     /translation="MKSSKLLALAGVTLLAATTLAACSGSGSSTKGEKTFSYIYETDP
                     DNLNYLTTAKAATANITSNVVDGLLENDRYGNFVPSMAEDWSVSKDGLTYTYTIRKDA
                     KWYTSEGEEYAAVKAQDFVTGLKYAADKKSDALYLVQESIKGLDAYVKGEIKDFSQVG
                     IKALDDQTVQYTLNKPESFWNSKTTMGVLAPVNEEFLNSKGDDFAKATDPSSLLYNGP
                     YLLKSIVTKSSVEFAKNPNYWDKDNVHVDKVKLSFWDGQDTSKPAENFKDGSLTAARL
                     YPTSASFAELEKSMKDNIVYTQQGSITYLVGTNIDRQSYKYTSKTSDEQKASTKKALL
                     NKDFRQAIAFGFDRTAYASQLNGQTGASKILRNIFVPPTFVQADGKNFGDMVKEKLVT
                     YGDEWKDVNLADSQDGLYNPEKAKAEFAKAKSALQAEGVTFPIHLDMPVDQTATTKVQ
                     RVQSMKQSLEATLGADNVIIDIQQLQKDEVNNITYFAENAAGEDWDLSDNVGWGPDFA
                     DPSTYLDIIKPSVGESTKTYLGFDSGEDNVAAKKVGLYDYEKLVTEAGDEATDVAKRY
                     DKYAAAQAWLTDSALIIPTTSRTGRPILSKMVPFTIPFALSGNKGTSEPVLYKYLELQ
                     DKAVTVDEYQKAQEKWMKEKEESNKKAQEDLAKHVK"
BASE COUNT        23041 a        18023 c        14634 g        23455 t
ORIGIN      
        1 tcaaacgggg ttcccctcat ctgcggtggg cactcataca agctgccaaa gcatgccctc
       61 gcttttcacc tgcttttaag gcctatctta agactaagtt agaataagga aaacattaca
      121 atgtagccat catccacctt gcaaaaaaac ttatccgaac cctgttttat atcctaaaaa
      181 agagctgcca tttgacgaac aaaaagtgat gtaatttctg aaattaacac aggattacct
      241 ttgaaaaaat ggactttttc aagggctttt tgccgtgctc taaaatcatc gccaaatcat
      301 caaattgaaa taagaaatag tttagataaa actattgact tttcttatag tttgtctttt
      361 ttctatcttc cattatatca tactttttca gtctatggta gctctcttta aaaggcaccg
      421 atactgccgc cacctccgcc tccagagaag ccaccaccag aacttccact tccagaagat
      481 acagagtagg tgcttgctgt atttgcgaca ctagcataat ggctcatttg cgcgcttgaa
      541 tgataaaaca gactgtgcca gccataagct acatagagat tgatatctgg attttccact
      601 tgaatctgat gaaccttcat caaatgacta accttgtccg catagccaaa taaggtcgca
      661 tagaccaaga ggcgattcca gaccacaata ctttccagtt cagcctgatc caatcgtgca
      721 atctcacgca acatattttc aaaactggtc cagagatagt agacctcagc tcccgcttca
      781 tttagaacac catcacgatt atctagtcga agcttccaat aatagaaaac agacaaaact
      841 aaccctagaa aaccaagtat tggcaaaggg aggtaaagat agccatgaac gtctaaactg
      901 tacaagaaca aaccaaatcc gataaatagg ggcaggatag tcaaggcacc catacccact
      961 tgcaaggcct tttccccacc agttaaagga cgataataat ctgggagccc ccagaaggaa
     1021 actcgttttc tcactccttc ttgcatctgg ttcaatacct cttcaaaaga agatttgagt
     1081 tgaagccctc ttgcttgaat ccgtttttca tcagaaactt tggctctacg ataaagacta
     1141 tcagatacct tgtaatccgc aaacaaattg gaaagagttt cttctttttt acctgaaaaa
     1201 gctagattta ggcagtcttt ctcaaagctt gacaaaccat cttcttttac tagcctcaaa
     1261 ccaactgcat ctccttctga aatgatagag acattcccac ggtctatcac atctagcaag
     1321 gtagcttgaa taagttgatc aaaggtgaat tttccagctc ccttgaccaa gggactcact
     1381 tcctccaagg aggtcgagta gactgcttct gataaaacca taggctctaa ttccattggt
     1441 ggttcataga gacgatgatt tttggcatat ttgactgaag gagtggtctt tcttctataa
     1501 ataaaataga agcagacact caataacaag gagatagaaa ggatcgaagg gaggacccaa
     1561 gtaacaagtt gtttactctg atctttttct ctaacaatcg agtcttctat cttattaaac
     1621 tcttctaaac gattcccttt caatccctga tccctagcgc tagcaaaatc ggtccgaggc
     1681 caataggcat gcaactcaac tccacgctta gccggaagat tgtctaaacg gatagtataa
     1741 tcaaggttac tcttttcaat cgttccctct ctaaaaagtt tccctgtatg gaaaaagagt
     1801 ttttcagctc ccttgtctcc ccttacatga aattcaaact tttcaataga ctctgaacta
     1861 tctgtcagag gttgccaatt taattcagcg atatcatcat aaaggaaaag taaatttttt
     1921 aagttccaga cgaggtcaac ttcaactatg tcgccctcct gacctggatt atagactctc
     1981 acagtataac catccgcttc ttctgttact tcgctagtca catctgctag ttctgcaccg
     2041 tttttcgcgg cctgaacctt tggatgaggg tcaatgtcaa acccgctagg catcttacca
     2101 gcacgtccaa gtcccacgat ttgtccctta aagtcctcct caaactggta aactatcttc
     2161 tgtctaaact ctgccgtatt atctgcatga atatacaaat ccccttgata agagtttatc
     2221 ttgaaatcaa tggcaaaaac agagagtgga agaaggcaaa acaagcctaa caccagtaag
     2281 aaaaaagttt ttttcatcaa ctaagccccc tttttatctt tcttatcatt atagcatttt
     2341 ttcgtaagta aaggcttact tatgttgaaa aattacgcat ttttcgataa aataggagac
     2401 agttattttt taatagatca gaataggaga aatcatgaga aaaatatact tatctatttt
     2461 cacaagtctc ttgctgatgc taggacttgt caatgttgct caagccgatg aatatttacg
     2521 catcgggatg gaagcagcat atgctccctt taactggacc caggatgatg atagcaacgg
     2581 agctgtcaaa atcgatggga ccaatcagta tgccaacgga tacgatgttc aaatcgccaa
     2641 gaaaatcgct aaggacttag gtaaaaaacc tttggttgtt aaaaccaagt gggaaggtct
     2701 agtccctgcc cttacttctg gtaagattga catgattatc gcaggtatga gtccaactgc
     2761 agaacgcaaa caagaaattg ccttttcgag cagttactac actagcgaac cagttttgct
     2821 tgtcaaaaaa gattctgcct acgcaagtgc taaatctttg gatgacttta acggtgcaaa
     2881 aatcacttct caacaagggg tctacctcta cgacttgatt gcacaaatcc caggtgctaa
     2941 aaaagaaaca gccatgggag acttcgctca aatgcgacaa gctcttgagg ctggtgtcat
     3001 tgatgcttat gtttctgaac gtccagaagc actgactgct gaagctgcga actctaagtt
     3061 caagatgatt caagtagaac ctggtttcaa aactggggaa gaagatacag ctatcgctat
     3121 cgggcttcgt aaaaatgaca atcgtattag ccaaatcaat gccagcattg aaaccatttc
     3181 aaaagatgac caagttgcct tgatggatcg tatgatcaag gaacaacctg ccgaagctac
     3241 aacaactgaa gagactagca gtagtttctt tagccaagtc gctaaaattc tttctgaaaa
     3301 ctggcaacaa ctcttgcgtg gtgctggtat cactctttta atctctatcg tcggaaccat
     3361 cataggtctc attattggac ttgccattgg tgtcttccgt actgctcctc tctctgaaaa
     3421 caaagccatt tatggccttc aaaaactagt cggctgggtt ctcaatgtct acattgaaat
     3481 tttccgtggt acgccaatga ttgttcaatc gatggttatc tactatggaa ctgcccaagc
     3541 tttcggtatc aaccttgacc gtacactagc tgctatcttc atcgtttcaa tcaataccgg
     3601 tgcctacatg actgaaattg tccgtggtgg tatcctggca gttgacaagg gacaatttga
     3661 agctgcgact gctcttggta tgactcataa ccaaaccatg tgtaagattg tcctacctca
     3721 ggttgtccgc aatatcctac cagcaactgg taatgaattt gtcatcaata tcaaagatac
     3781 atctgtattg aacgttatct ctgttgtcga actttatttc tcaggaaata ccgtggcaac
     3841 acaaacctat caatacttcc agacatttac aatcatcgcc gtgatttact ttgtcctcac
     3901 cttcaccgta acacgtatcc tacgctttat cgagcgcaga atggacatgg atacctacac
     3961 tacaggtgct aaccaaatgc aaacggagga tttgaaataa tgacacaagc aatccttgaa
     4021 attaaacacc tcaaaaaatc ctatggacaa aacgaagtgc taaaagacat ttctctcact
     4081 gtccacaagg gagaagttat ttctatcatc ggaagctctg gaagtgggaa atcaaccttc
     4141 ctacgctcca ttaacctact tgaaacgcca actgatggac aaatccttta tcatggacaa
     4201 aacgtcctcg aaaaaggcta tgacctcacg caataccgtg aaaagttagg gatggttttc
     4261 caatccttta acctctttga aaatctcaac gttcttgaaa acacaatcgt cgctcagaca
     4321 actgtcctta aacgcgaacg cacagaagct gaagaaattg ccaaagaaaa cctggaaaag
     4381 gtcggcatgg gagaacgcta ctggcaagcg agacccaaac aactctcagg tggtcaaaaa
     4441 caacgtgtgg ccatcgctcg tgccctttca atgaatcctg acgccattct ctttgatgaa
     4501 ccaacatcag ctctcgatcc agaaatggtt ggagaggtcc tcaaaatcat gcaagatctg
     4561 gctcaggaag gcttgaccat gattgtcgta acccatgaaa tggaatttgc ccgtgatgtc
     4621 tctcaccgtg ttatctttat ggataagggt gtgattgctg aagaaggtaa accagaagac
     4681 ctcttcacta atcctaaaga agaccgtaca aaagaatttc ttcaacgtta tctcatactc
     4741 aatgaaaatc aaagagcaaa ctaggcagct agccgcaggt tgctcaaaac actgttttga
     4801 ggttgcagat agagctgacg tggtttgaag agattttcga agagtatcaa ataaaaagaa
     4861 aaggctgcat caaccgtgca gtctttttgc tgtcctcaaa atgaaaaggc agattctcta
     4921 tctctactac ttgaaggtca agaatccacc gttatccaaa gattaatctt caaatttttc
     4981 atgatttttt tcatagaaat caattaagcc tagggctgtt tcaaatgaaa tattttttac
     5041 ttttgcacga ccctgcgcca gagcaatgat agacatttca cgcgcattcg tttctttaga
     5101 gatacggtag cctgtgattt tcttatcacg aacccagcca acaactgatt ctactttttc
     5161 aaagtttgac ttagccatgt ttttctccta ttttcttctt tataatattt aattgtatac
     5221 gtttttacta cttttgtcaa taaaaaaaac atatattcaa cgaaaataat tagttcagaa
     5281 ttttcttact tcctttttaa atccgataat atataggttt tgctagcctc tacaccataa
     5341 atatttgcta ataaaaatac tgtattatta ccctcttaag gtgcaaaatt attcaagttc
     5401 ttaaaaaatg cttctctatt tccgtaagat agcttatttc ttcgatttaa gaactgaaga
     5461 tgatagttct aacctttaga aatccaagcc ttctctagct caaaaactcc tatctttctt
     5521 cctcaataaa tcatctgaga gataggtatt ccttatatcc ttcaaattca tcactccttt
     5581 ggatattgag gtgctagcct agaagcagac acccgattat ctaaaccatc cttaatagag
     5641 atgacaagac agataagctc agttaattac ttatatatct ttttaatatg gtatatttgt
     5701 caacaaaaag aaatcaaatc ataccttata ctcaatgaaa atcaaagagc aaactaggaa
     5761 gctagccgca aattgctcaa aacactgttt tgaggtttca gatagagcta acgtggtttg
     5821 aagagatttt cgaagagtat taaagacagt atgactatgc ttgtcaatag ataggaaatc
     5881 aaaatgaagg atggaaatct gagccaaaca tcataagtgc tataatgaac agaagtaaga
     5941 attgcacgat aagttttcta aaaccatagg aatcgtcccc tttcttcatc ttcattatag
     6001 cacatataca tcagttgtac aaataatatg atattttttt attagtcctc agacaagcat
     6061 attataaagc gtttcattac catttaagtt aatataagct ggatcaaaac cttccattct
     6121 acggatcaaa cctgcataat catgcttatc tgccaaagcg atcccaatca atactgggcc
     6181 tgttcccttg ctagctcgtt tgatatactc aaaacgtgtg atatcatcat ttggccccag
     6241 gatatcattt acaaactcac gcaaagctcc tggacgctgt gggaaattga ccacaaagta
     6301 atgtttgata ccatcataaa tcaaggcacg ctcttccatt tctggcatac ggttgatatc
     6361 attatttcct ccagaaatga tacaacaaat ggttttcccc ttaatatatt cagctaaaac
     6421 ctctaaagag gcgatactag ccgctccagc aggttctgcg actatccctt gcttagagta
     6481 aaggtcaatc aaggtttcag aaatcaatcc ctcatcgaca cctaccaaag tttgaatatg
     6541 ttgacgagtt gcttcatagg tcaactgacc taccttttgc acagcaatcc catccgcaaa
     6601 tttatcaatt tccttgagtt tgactggacc tccagcctca aaggcagctt tcatggaacg
     6661 cgctccattc gcctctactc cgataacctc aatctctgga cttgtttcct tgatataggt
     6721 agaaaccccg gcaatgagac cgccaccacc aacaggaacc aagacagcat caaaatcaat
     6781 cgattctttt cgagcttctt ctaaaatctc ataagcaact gttccttgac ctgcttgaac
     6841 atgagcatca tcaaaaggat caataaaggt acgattttca gagactgtaa attcttgagc
     6901 tgctttggct gaggcatcaa aggtatctcc aactagttta atagttacaa aatccccacc
     6961 aaaaaagcga acctgaccaa tcttttgttg tggcgtagta ataggcataa agatagtagc
     7021 aggaattttc atttcattac aagtataggc tactccctgc gcatgatttc ccgcagaagc
     7081 gcagactacc ccacgttcac gttcttcctt gctgagctgg gaaatggcat aataggcacc
     7141 acgaatttta aaggagcgaa cacgctgggc attttctttt ttcaaataaa tcttagcacc
     7201 atacttctcc gataaataat gatcgtaatc cagtggagta ttcacaacca caccgttcaa
     7261 gaccttgtga gccttgatta tatcttttga acttaacata taaaacctct ttttctataa
     7321 aaaacagtca ctaatgactg ttttttagtt attcatctcc gaaaacttca gtaacacttt
     7381 catggtattt atgagccata cgaatcgaaa actctttagg aagttcataa cgatttgtgg
     7441 aaatccaatc atataaccat tctaccaaac tttcttcact atcattacga tggaagataa
     7501 aatagtttaa aatttcttta tattctacat cattcaaatc caacgtgtct acaaattgac
     7561 tacgaggaac aaaattagaa tctaattttc ttagttgatc tgtcaattct cccaattgta
     7621 aatccaactg aaaaaatagt ttttgcagtt gcctatcagt ttcatcacat cctgtcttga
     7681 tagaaaacaa attggtaata ttcatatgat ttcaacccct aaataagtac atctaatatc
     7741 ccacgaatag ctgaagctaa agttttcgca gtccagtcat ttaaacccga ttctttcaat
     7801 ccagatgcaa taatttgctc tatttgatat aaaccgccat ctatcgtctc atttattctg
     7861 cgaagaggac cttcaatata ggataaagct tctccgaatc taacagctga tttaggtcct
     7921 aatgatttac caactatatt tgttaatgtt ttttatttct caaaatccat ttcgctatat
     7981 aacgagcaga tttagtcgca ccagctctct caaacggaga atgaatttca agaccttctt
     8041 ctctagctat ttgtgccaat ttgaagaatt gttcaaaggt catatgcaac ctaccatctt
     8101 caaaattagc atcatcataa atgttaatta cagcattttc atcatacgac caatctgctt
     8161 tattttggtc tgctagcact attaccgacg gtgtaattac attatacaac tagaaccaat
     8221 aataacgatg caatttttct cataatcttt ttcataaaat catctccagc gctatatatt
     8281 tctaattagt tatagatttt gaatgcatca tcgtcgtttt taccaacaaa tggcattgct
     8341 ttacgcaatt ctgcaccaac tttttcaatt tcaaggttag ctgcttgttc acggtaagca
     8401 gtcaattttg gacgtccagc tttatagtca tttacaaagt catttgcaaa tttaccattt
     8461 tggatgtctg ccaagacagc cttcatattt tctttaactt gttcagtgat tacacgtgga
     8521 cctgatacat agtcaccgta ttcagcagtg tttgaaatag attgacgcat tttcttgaat
     8581 ccaccttcgt agatcaagtc aacgatcaat ttcatttcgt gaagaacttc aaagtaagcc
     8641 aattctggag cgtaacctgc ttctgtcaag acttcgaaac ctgcttcgat aagggcagtc
     8701 aaaccaccac aaagtacagc ttgttcacca aacaaatctt cttcagtttc ttctttgtaa
     8761 gttgtttcaa gaagacctac acgagccgct ccaacacctt tacaccagtc catagcaatg
     8821 tttttagcat ttcctgttgc atcttggtat actgcataaa gagctggaac accaaatcct
     8881 tcttcgtaag tacgacgtac caagtgtccc ggtcctttag gagcacacat gaagacatct
     8941 acatccgcag gaactttgat aaattcaaag tggatgttga aaccatgggc aaatccaact
     9001 gcgtttccag cttccaagtt tggagcgatt tctgcttcgt acaattcttg ttgaatttcg
     9061 tctggcgcca agatcatgat aacatcagcc aacttagtag cttctactac tgtgtaagta
     9121 tcaaatccat cttcttttgc tttatcaaaa gatttacctg gacgtacacc gataataacg
     9181 tcacgacctg aatcacgcaa gttttgagca tgcgcatgtc cttgtgaacc ataaccgata
     9241 acggcgattt ttttaccgtc aagtgctgct actttaacat ctttttcata ttccatttga
     9301 actgtcatag cttttctctc ttttctatta tttattgcct tttaggctgg tttaataaat
     9361 ttaagttgga tttttaatcg cgggtaaatc cagttgcacc cgttcgagca atattgcgaa
     9421 taccgtatgg gcgaatgact cgcaataggg cttcgctctt ttctgcattt cccgtcatct
     9481 gaatggtaat cgagcttggc gctacgtcta ccactgttgc acggaaaggt tgaataatcg
     9541 ctaaaatctc agctctcttc tcagctggcg ctgacatctt aaccaaaatc acctcgcgct
     9601 ccaaatgagg cttgtctgta atatctcgaa tgcgaatcac atcaatctga cgattgagct
     9661 gtttgatgat ttgctccact tcatcatgag aagcaacatc aataataata gtgatacgcg
     9721 atacattcgg atcttctgtt gctccaacag agatgctttc aatattaacc tgacgacgag
     9781 ataggacacc tgtaaagcga ttgaggactc ctgaacgatt ttgtagtttt gctgttaaca
     9841 ttctacgcat ggaactgcac ccccaacatc tcatgattac tcttaccagc cggtaccatt
     9901 ggtaacacct gttccttacg agaaatatct acctcaatta gcataggaac atcctcagtg
     9961 atgacttcaa ggtcttgagc caaggtctca ggattgtcaa acttatagtt tttaatacca
    10021 taagcctgcg ccatcaattg gaaatcagga agggtatcaa agaccgactc tgatgttctg
    10081 ccttcataga aggattcctg ccactggcga accattccaa gtgaatgatt gttcagcata
    10141 accaccttga ttggcacctt gtaaatattc aaaatagcca actcctggtt ggtcatttgg
    10201 aaaccaccat ccccaacaaa caagactact tccttatctg ggttagcaat tttagcaccg
    10261 attgctgctg gaattccaaa gcccattgtt cccaaaccac ctgaagtcac taactgacgc
    10321 tcattttggt agggataata ctgagctgtc cacatttggt gttgaccaac gtctgttacc
    10381 acaatggcat ctccattcgt caattcacca attcgttcaa taactgcttg cggttgaacc
    10441 acacgctctt tcttgtcata agaacgaaca cgattcttgt ctttagtgac tttctcaatc
    10501 cacttttcag tattgttgtg aactgttggt tctgctagca acatttgcaa ggccttctta
    10561 gcatctccaa ctacaggaat gtctgcactg ataatcttgc caatctcagc tgggtcaata
    10621 tcaatgtggg caaccttagc attcttagcg aaagtcttag gattccccgt caaacggtca
    10681 tcgaaacgag aaccaatact aatcataaag tccgcttccg tcatggcaat atttgctgcg
    10741 aatgacccgt gcatgcctcc cattccaaga aagagtgggt gactcgttgc aatcgttcct
    10801 tgtcccaaaa gactggttac cactggaatt tgatagcgtt ctgcaaattc atttagttcc
    10861 gtagcagcct cagcataact aattccacca ccagctaaca agactggctt tttagccttg
    10921 gacaattgct tcaagatttt cttgatttgc atatcattcg gctcaagagt cggctgataa
    10981 cttggtaaat tcacttctgg tgaataaatg aagtctgttt ctaaagcaga tatgtctttt
    11041 ggtaggtcaa ttacaactgg ccctggacgg cctgtagttg cgatatggac agcttccgta
    11101 atgatacgcg gaatatcagc tgtctcacga acttggtaat tgtacttagt gattggcatg
    11161 gtaattccta cgatgtctgc ctcctgaaag gcatccttcc caatccctgc tcgcgccacc
    11221 tgacctgtaa agaccaaaag gggaacgcta tcgctcatag catccgcaat ccctgtaatg
    11281 gcatttgttg ctcctggtcc actagtgacg acggcaacac ccaactttcc agttgatttg
    11341 gcataacctt cagcttcatg caaacaacct tgctcatggc gccctagaat gtggcgaatg
    11401 cctttaaaat tatatatcgc atcataaaaa ggcaaaaccg caccaccagg ataaccaaag
    11461 atggtatcaa ctcctaaatc acgaagtgtt tccaaaacta ggtccgaccc cgtcttagga
    11521 gattctaaac tgattttctc cattgttccc ctttctttcc tcttaaaaat aacttgttac
    11581 tatcatacca ttttttcaaa atttttcaag ataaaagaag aaattttctg aattttctat
    11641 tttaacgttt atttatgaat gttatttttg tttttattaa aaagataccg atttcattta
    11701 ctaaaaaaga aaaaagaact gatttctcag tccttcatta atcttattcc acactaaata
    11761 ggtatgggta aacaggttgt tgaccttggt gaatctcgac ttcaacgtct tcgaattctt
    11821 ctacgatttc ttgagcgatt tcattggcaa gttcttcgct tccgtcttca ccgacataga
    11881 aggttacgat ttcactatct tcatccaaca tatgtttcaa ggtttcagtc aatgtttggt
    11941 gcatatcagg gtttgacaca agaatttttc catccaccat acctagatta tcgttttcat
    12001 ggatttctaa gccatcgatc gttgtatcac gcacggctgt tgtgacgctt ccgctaacga
    12061 catcgctaag agcagctgtc atacgctctt ggttttcttc aatggacttg cttggatcaa
    12121 aggcaagaag acttgtcata ccttgaggaa gagtgcgagc ctctaccact actgctggtt
    12181 gctccaaaac ttctgccgca gattgagctg ccatgaagat gttcttgttg tttggcaaga
    12241 agatgatgtt acgggcattg acctgttcaa cagccttgat aaagtcttct gttgaagggt
    12301 tcatggtttg accgccttcg ataacataat ccacgccttg agaacagaag atatctgcta
    12361 gacctttacc agccaccaca gcaatcaaag catactcttt ttcttcagcc gacttgataa
    12421 cttgagtagc ttctttctca acctgtgctt cgtgttggtt acgcatattg tcaactttta
    12481 ccttgaccaa gctaccatat ttgagacctt cttgcataac aagtcctgga tcttctgtat
    12541 gaacatggac tttgacaatt tcatcatcgt taacaacgag gagagaatcc ccaagctcat
    12601 ccaagtagtt acggaattca tcgtagtcaa aatctttagc ataggttgga ccttgcttaa
    12661 gagctaccat gatttcagta cagtaaccaa acgtgatgtc ctcagtcgct acgtgaccag
    12721 ctacagactt atgatgctct acattgatca tctcactcat gttggcagga gtcgctacaa
    12781 agtcctcaga tgcaatatat tcgccagtaa gggctgaaag gaaaccttcg tagatgaaga
    12841 ccaatccttg accacctgag tccacaacgc caacttcttt caatactgga agcatgtctg
    12901 gtgttttagc tagagctgtt ttagcacctt ccaaggctgc gcgcatgact tcaacagtgt
    12961 catctgtttg ctcagctttt ttcttagcac cgatagcagc tccacgagaa actgtcaaaa
    13021 tcgttccttc aacaggtttc atcactgcct tataggcaac ttccacacct gattggaagg
    13081 ccagagccaa gtcttgacct gttaactcgt ctttatcctt gatagcttgg gaaaatccac
    13141 ggaaaagctg agacgtaatc actcctgagt tcccacgcgc acccatcaaa agccctttgg
    13201 caagaatgct cgctacttct ccaactgtag aagctggctt gtctgcaact tctttagcac
    13261 cattttcaat ggtcattccc atatttgtcc cagtatctcc atctggaact ggaaagacgt
    13321 ttaatgaatt gacatattca gcttgcttat tcaagcgagt tgatgcagcc tgcaccattt
    13381 cttgaaataa gctagtagta atttttgaca cggttattct cctacaactt tgatattttg
    13441 aatgtagaca tttacagtct gagcagtaat tccaagctgg ttttccaagc taaaggcaac
    13501 acgctcttga atgttttttg acacttcact aatctttgtt ccgtagctta acacggtata
    13561 tacatcaact gcaatactgc catcttcggc tgcctttacg acgacacctt tagaataatt
    13621 ttccttacct agcagggctt ggaaattatc tttgagggca tttttactag ccataccgac
    13681 cacaccaaaa atctcagttg ctgctccacc tacgacggtt gcaatcactt catctgttag
    13741 ttcgatttga ccatcttttg tattaatttt tacagtcatc ctttttacct caactagttg
    13801 atactctatt ttatcatatt tcagcccaag tgtaaaagca gaatgatgta tcagcggata
    13861 tttactctat ttttcaaacg atgttatacc cacaataaaa gaaaaaagac cctaaggtct
    13921 cctttgcttt tattattaaa cgcgttcaac tttacctgat ttcaaagcac gagctgaagc
    13981 ccaaactttt ttaggtttac catcgataag aacagtaact ttttgaaggt ttggttttac
    14041 ggcacgtttt gtttggttca tcgcgtgtga acggttgttt cctgatacag tcttacgacc
    14101 tgtaaagtaa catactttag ccattgtgtt ttcctcctat tagatctaat atagcggatg
    14161 tgctagcacc acataccgta ctatgttatc acactttctt gttttttgca agggaattgg
    14221 aagatttttt atttgtgtct taaatcaggt cttgcgtgac attttctgct ctccacatgc
    14281 catcgttgat taacagaaca ccagaattaa aattatgtgt ataaaaatca tctctaactg
    14341 cagctaaggg tatagccgtc aagtccaaat cccacagctc atctatcgat tttcttacaa
    14401 caatatctga atccaaatac agtacacgag actcgcttac atactttgga ataaaatacc
    14461 taaaaaagcc gcatatgaaa gtccctcaaa ggggagacga taacctttca gaatattact
    14521 gtcaatctaa acattcacaa tctcactatt caaagtctct agtctttttt ccatcaattg
    14581 gaaccattct cgcggaaggt catcattaaa aacataaaac ttaagattat aatgatgaac
    14641 acaaagagat tttattgttg tttcaacttt atccatataa gcattatctg cacctaagac
    14701 aatcgctttt ttctcttttt tctcttcttt cactttttat ctcatttctt tttattccca
    14761 tcatatgttt ctacgtaacc attattttcg cctattcgtt cgtaaaacca taccagtgga
    14821 gattttagat gaagtcccat tacggtttac aatttttaca ttacgacacg gagttttaca
    14881 aatcgatttc atttgccaaa cgtagttagt gaggcagtta gctagttcgc caaatagcga
    14941 ctagcgtcca acaatttgga actttagttc caattgttgg tactgagtca catcttctcc
    15001 tctaactcta cgtctggata cttgtcagca aaccagcgga gggcaaagtc attttcaaag
    15061 agaaagactg gttggtcaaa acggtctttg gctaagatat tgcgacttga cgacatccgt
    15121 tcatccaagt cctcaggctt gatccaacga acggtctttt tacccattgg gttcataact
    15181 acttctgcat tgtactcgcc ttccatgcgg tgtttaaaga cttcaaactg gagttgacct
    15241 acagcgccta gcatgtactc acctgtttgg taattcttat aaagctgaac ggctccttct
    15301 tgcaccaatt gctcaatccc cttgtggaag gatttttgct tcataacatt cttagcagaa
    15361 actttcatga aaatttcagg agtaaaggtt ggcagtggtt caaattcaaa cttgttttta
    15421 ccaactgtca aggtatcccc aacttgataa gtaccggtat cgtaaacccc gataatatca
    15481 cctgccacgg cattgatcac attctcacga ctttccgcca taaactgggt aacattagat
    15541 agtttggccc ccttaccagt acgagggaga ttgacactca tgccacgctc aaattcgcct
    15601 gatacgatac ggacaaaggc aatacggtca cggtgacgag gatccatgtt ggcttggatt
    15661 ttaaagacaa agcctgagaa atccttgtca taaggatcca caatttcacc gtctgttttc
    15721 ttgtgaccat gtggttctgg agcaaacttg aggaagattt caaggaaggt ctgcacacca
    15781 aagtttgtca gggctgaacc gaaaaagaca ggcgtcaatt ctccagccag aatagcttcc
    15841 tctgaaaact cattcccagc ttcatttaaa agctcaatgt catccttgac ttgctcgtag
    15901 aaaggattgc taccaaagag tttgtccccg tcttctagac tggcaaaacg ctcatcccct
    15961 ttgtaaagct ctaaacgttg gttatagagg tcatacaagc cctcaaaggc tttccccatc
    16021 ccgataggcc agttcatagg gtagctagca atgcccaaga tttcttccaa ttcttgcaag
    16081 agatccaaag gctcacgacc gtcacggtcc agcttgttca taaaggtaaa aactggaatg
    16141 ccacgatgtt tcacaacctc aaacaatttc ttggtttgag cctcgatccc cttggcagag
    16201 tccacgacca tgaccgcagc atccaccgcc atcaaggtac gataggtatc ttctgagaag
    16261 tcctcgtgcc ctggcgtgtc taagatattc acgcgcttgc cgtcgtagtc aaattgcata
    16321 acagatgaag taacagaaat cccacgttgc ttctcgatat ccatccagtc agatttagca
    16381 aaagtccctg ttttcttccc ttttaccgta ccagcctcac gaatctcacc cccaaagtag
    16441 agtaactgct cagtgatggt tgttttcccc gcgtccgggt gggagataat ggcaaaggta
    16501 cgacgtttct taatttcttc ttgaatattc ataagttctc tttctttgat tctctatttt
    16561 tcttgtttca atagctgaga atgattttta cattggattt taccattcct ttcaacattc
    16621 cattatatcg gattttagca tttttttcaa tttctatttc ttttcacttc cccctccctt
    16681 atttatagga aaatatggta aaatagaaca gactaaaaat catcatttca cgaaaggatg
    16741 caagatgaaa attacgcaag aagaggtaac acacgttgcc aatctttcaa aattaagatt
    16801 ctctgaagaa gaaactgctg cctttgcgac caccttgtct aagattgttg acatggttga
    16861 attgctgggc gaagttgaca caactggtgt cgcacctact acgactatgg ctgaccgcaa
    16921 gactgtactc cgccctgatg tggccgaaga aggaacagac cgtgatcgct tgtttaaaaa
    16981 cgtacctgaa caagacaact actatatcaa ggtgccagct atcctagacg atggaggaga
    17041 tgcctaatga cttttaacaa taaaactatt gaagagttgc acaatctcct tgtctctaag
    17101 gaaatttctg caacagaatt gacccaagca acacttgaaa atatcaagtc tcgtgaggaa
    17161 gccctcaatt catttgtcac catcgctgag gagcaagctc ttgttcaagc taaagccatt
    17221 gatgaagctg gaattgatgc taacaatgtc ctttcaggaa ttccacttgc tgttaaggat
    17281 aacatctcta cagacggtat tctcacaact gctgcctcaa aaatgctcta caactatgag
    17341 ccaatctttg atgcgacagc tgttgccaat gcaaaaacca aaggcatgat tgtcgttgga
    17401 aagaccaaca tggacgaatt tgctatgggt ggttccggtg aaacttcaca ctacggagca
    17461 actaaaaacg cttgggacca cagcaaggtt cctggtgggt catcaagtgg ttctgccgca
    17521 gctgtagcct caggacaagt tcgcttgtca cttggttctg atactggtgg ttccatccgc
    17581 caacctgctg ccttcaacgg aatcgttggt ctcaaaccaa cctacggaac agtttcacgt
    17641 ttcggtctca ttgcctttgg tagctcatta gaccagattg gaccttttgc tcctactgtt
    17701 aaggaaaatg ccctcttgct caacgctatt gccagcgaag atactaaaga ctctacttct
    17761 gctcctgtcc gcatcgccga ctttacttca aaaatcggcc aagacattaa gggcatgaaa
    17821 attgctttgc ctaaggaata cctaggcgaa ggaattgatc cagaggttaa ggaaacaatc
    17881 ttaaacgcgg ccaaacactt tgaaaaattg ggtgctatcg tcgaagaagt cagccttcct
    17941 cactctaaat acggtgttgc cgtttattac atcatcgctt catcagaagc ttcatcaaac
    18001 ttgcaacgtt ttgacggtat ccgttacggc taccgcgcag aagatgcgac taatcttgat
    18061 gaaatctatg taaacagccg tagccaaggt tttggtgaag aagtgaagcg ccgtatcatg
    18121 ctgggtactt tcagtctttc atcaggttac tacgatgcct actacaagaa ggctggacag
    18181 gtccgtacac ttatcattca agatttcgaa aaagtcttcg cggattacga tttgattttg
    18241 ggtccaactg ctccaagtgt tgcctatgac ttggattctc tcaaccatga cccagttgcc
    18301 atgtacttag ccgacctctt gaccatacct gtaaacttgg caggactgcc tggaatttcg
    18361 attcctgctg gattctctca aggtctacct gtcggactcc aattgattgg tcccaagtac
    18421 tctgaggaaa ccatttacca agctgctgct gcttttgaag caacaacaga ctaccacaaa
    18481 caacaacccg tgatttttgg aggtgacaac taatgaactt tgaaacagtc atcggacttg
    18541 aagtccacgt agagctcaac accaattcaa aaatcttctc acctacttct gcccactttg
    18601 gaaatgacca aaatgccaac actaacgtga ttgactggtc tttcccagga gttctaccag
    18661 ttctcaataa aggggttgtt gatgccggta tcaaggctgc tcttgccctc aacatggacc
    18721 tccacaaaaa aatgcacttt gaccgcaaga actacttcta ccctgataat cccaaagcct
    18781 accaaatttc tcagtttgat gagccaatcg gttataacgg ctggattgaa gtcgagctag
    18841 aagacggtac gaccaagaaa attggtatcg aacgcgccca cttagaggaa gacgctggta
    18901 aaaacaccca cggtacagac ggctactctt acgttgacct taaccgccaa ggggtacctt
    18961 tgattgagat tgtatctgaa gccgatatgc gttcgccaga ggaggcctat gcttatctga
    19021 cagccctcaa ggaagttatc cagtacgctg gcatttctga cgttaagatg gaagaaggtt
    19081 ctatgcgtgt ggatgccaac atctcccttc gtccttatgg tcaagagaaa ttcggtacca
    19141 agactgaatt gaagaacctc aactccttct caaacgttcg taaaggtctt gaatacgaag
    19201 tccaacgcca ggctgaaatt cttcgctcag gtggtcaaat ccgccaagaa acacgccgtt
    19261 acgatgaagc gaataaagca accatcctca tgcgtgtcaa ggaaggggct gctgactacc
    19321 gctacttccc agaaccagac ctacccctct ttgaaatttc tgacgagtgg attgaggaaa
    19381 tgcggactga gttgccagag tttccaaaag aacgtcgtgc gcgttatgta tctgaccttg
    19441 gtttatcaga ctacgatgct agtcagttga ctgctaataa agtcacttct gacttctttg
    19501 aaaaagctgt tgccctaggt ggtgatgcca aacaagtctc taactggctc caaggggaag
    19561 tcgctcagtt cttgaatgct gaaggtaaaa cactggaaca aatcgaattg acaccagaaa
    19621 acttggttga aatgattgcc atcatcgaag acggtactat ttcatctaag attgccaaga
    19681 aagtctttgt ccatctagct aaaaatggcg gtggcgcgcg tgaatacgtg gaaaaagcag
    19741 gtatggttca aatttcagat ccagctatct tgatcccaat catccaccaa gtctttgccg
    19801 ataacgaagc tgctgttgcc gacttcaagt caggcaaacg taacgccgac aaagccttta
    19861 caggattcct tatgaaggca accaaaggcc aagccaaccc acaagttgcc cttaaactac
    19921 ttgcacagga attggcgaag ttgaaagaaa actagacaga acaaaaccag ccctaaggtt
    19981 ggttttttct tctctaccaa ctcccaataa ctattttggc tttatttcca gagtatttta
    20041 tggtaaaatg aagagtaata atatttatta aagaggtaaa aacatgattg aagcaagtaa
    20101 attaaaagct ggtatgacct ttgaaacagc tgacggcaaa ttgattcgcg ttttggaagc
    20161 tagtcaccac aagccaggta aaggaaacac gatcatgcgt atgaaattgc gtgatgtccg
    20221 tactggttct acatttgaca caagctaccg tccagaggaa aaatttgaac aagctattat
    20281 cgagactgtc ccagctcaat acttgtacaa aatggatgac acagcatact tcatgaatac
    20341 agaaacttac gaccagtacg aaatccctgt agtcaatgtt gaaaacgaat tgctttacat
    20401 ccttgaaaac tctgatgtga aaatccaatt ctacggaact gaagtgatcg gtgtcaccgt
    20461 tcctactact gttgagttga cagttgctga aactcaacca tctatcaaag gtgctactgt
    20521 tacaggttct ggtaaaccag caacgatgga aactggactt gtcgtaaacg ttccagactt
    20581 catcgaagca ggacaaaaac tcgttatcaa cactgcagaa ggaacttacg tttctcgtgc
    20641 ctaatctcta gaaagaggtc attctatggg aattgaagaa caacttggcg aaatcgttat
    20701 cgccccacgt gtacttgaaa aaatcattgc tatcgctact gcaaaggtag agggtgttca
    20761 ctctttttca aacagatcag tgtctgatac cctttcaaaa ctttcactcg gccgtggcgt
    20821 ttatcttaaa aacgtggacg aagaactcac agcagatatc tatctctacc ttgagtacgg
    20881 agtaaaagtt cctaaggtag cggttgctat ccagaaagct gtcaaagatg ccgtccgtaa
    20941 tatggctgat gtagaactcg ctgctatcaa tattcacgtt gcaggtatcg tcccagataa
    21001 aacaccaaaa ccagaattga aagatctatt tgacgaggac ttcctcaatg actagtccac
    21061 tattagaatc tagacgccaa ctccgtaaat gcgcttttca agctctcatg agccttgagt
    21121 tcggtacgaa tgtcgaaact gcttgtcgtt tcgcctatac tcatgatcgt gaagatacgg
    21181 atgtacaact tccagccttt ttgatagacc tcgtttctgg tgttcaagct aaaaaggaag
    21241 aactagataa gcaaatcact cagcatttaa aagtaggttg gaccattgaa cgcttaacgc
    21301 tcgtggagag aaacctcctt cgcttgggag tttttgaaat cacttcattt gacactcctc
    21361 agctggttgc tgttaatgaa gctatcgagc ttgcaaagga cttctccgat caaaaatctg
    21421 cccgttttat caatggactg ctcagccagt ttgtaacaga agaacaataa aaagaaaaag
    21481 tgtttgatag atatcaaaca ctttttcttt gcctcccact atctaaaaaa atgataatag
    21541 atataattgt aaacaaaaat ccagataggt tttgcatgat tgagaaagtt aaaaaaacta
    21601 tggcagagaa tcgttaatct cagattgtcg gtagaacgat aaacaagggc aaaaaagaaa
    21661 ccaatcagac tataatataa taaactaatt ggatctctgt gagatagtat caaatggcta
    21721 atcccaaaga taaggcctga taagatgaca tctaaatagt actttgactt aggaaagaag
    21781 gtattcataa aataccctct atcaagagtc tcctcaaaaa caggaccgat gattacaagc
    21841 aggacaaaag ataagatagt cgataaaaag gttggttgtc catttgaaag aaccacggta
    21901 aaatactcat catgaatatt cctatggtta atcaaatgag catagcgtgc ctaaaaatta
    21961 ccgagaatct gataaaccac ataagttgca aataaggaga agacaaatga ccagtcccag
    22021 ctctttttct tttttaacct ccaaattaat agaaaaggaa acttcccact aatcccactg
    22081 ttaaaataag agaatagaca tcagctccta accctaaaat gatcgtcaca tacaatccaa
    22141 ttgtttgtgg taaataggta gatagtaaaa taataagcaa aaatattcca aattgtctta
    22201 gtttctttgt gtttctcatc gtactttttt gaaagattac cctgttcgga agccgtactt
    22261 ccaagcatct atataagaat taagtgcccc ttgcctcata tagggagcaa attctctata
    22321 atataaccat ctactatatc catcttccca aacagcaaga ccacctgaag tttgctccaa
    22381 gtcctcagtt gaaagaactg taaatgtttc tgtacctgtc attgcaagta ccttcttaaa
    22441 atagattgtt gtaggctcac atttatagta tatttctttt tttgtctatt ttatagtcta
    22501 tctcctcaac tggcaatttt tcgacctgaa ttgcattttt ccataaaaaa tgagaccttt
    22561 ctagtctcat ttagtcattc ttagtatttt ctaaatcgtt gatagcgttc ttccagcaac
    22621 tcttctagcg gtttttgtga aagtctagcc agctccgttt ggagttcttt tttgacactc
    22681 ttaattagtt ctttactaga aagtcctact tcagaaatca ccttatccac cacgtccatt
    22741 tctaacagtt catgcgaagt gattttcatc agttctgctg cttccatggc gcgagtaccg
    22801 tccttccata aaatggaagc aaagccttct ggactgagaa tggcatagat agaattttcc
    22861 agcatccaga cacggtccgc gacagctaga gccagagccc cgcctgaacc accttcaccg
    22921 ataataatgg cgataatagg aactttcagg tcactcattt ccatgagatt gcgagcgata
    22981 gcttcccctt gaccacgttc ttccgctccg acaccaggat aagcacctgc tgtattgata
    23041 aaggtcacaa ctggacggcc aaatttctca gcctgtttca tcaaccgcag tgcctttcgg
    23101 tagccttctg gatgtggttg gccaaaattc cgtttgaggt tgtcttgcaa actcttgcct
    23161 ttttggatac caaccactgt tacagcttgg tctccaagcc aaccaatacc accaacaact
    23221 gcaccatcat cacgaaaaga acggtcacca tgtaattgga taaattcatc aaaaatgcct
    23281 gtcgcaaagt ccaaggttgt caagcgactc tgctcacgcg cttctctgac tatttttgca
    23341 atattcatct aggactccct ccatgcaatc tgactaggct agcaatcgta tctggtaagt
    23401 ctcttctttt gacaatagca tccacaaagc catgttctaa taggaattct gccttttgga
    23461 aatcctcagg caagctttca cgaaccgtat tttcaatcac acgacgccca gcaaaaccaa
    23521 ccaagctctg tggttcagcc agaatgatat cgccttccat agcgaaagaa gctgtcacac
    23581 caccagtcgt tggatctgtc aaaatggtca ggtaaaagag accagcattt gaatggcgtt
    23641 taaccgctgc agagatctta gccatctgca tgagactcat gattccttcc tgcatacggg
    23701 ctccaccaga ggctgtgaat aggacaactg gtaatttttc gacagtcgca tactcaaaca
    23761 aacgagtgat tttttcacct acaaccgtac ccatagaagc catgataaaa ttagaatcca
    23821 taatcccaag agccacagtc tgacctttaa taagagcagt tcctgtcaca acggcttcat
    23881 gcagacctgt tttttcacgc atagatgcca gtttcttttg gtaaccaggg aaatgcaagg
    23941 gatccttgct ttcaatccct gtaaacaatt ctttgaaggt tcccatatca atcgtcaaag
    24001 ccaagcgttc ttgggcagaa atacgaaagg tatagctaca gtgcggacag atacgttcac
    24061 ttcccagatc cttctgatag atggtatgct tacagcctgg acactgggaa aataattcat
    24121 ctggaacctc tggcttagct tgaggttttt ccctaaccga acgattggga ttgattcgaa
    24181 tatacttatc ttttttacta aatagagcca ttgattcccc ttttcggttt aaactcttaa
    24241 agtcatttta ttctttttct tgatatttag gtaagaaggt ttccatcaag aaggaagtat
    24301 cataatcccc agcaatgaca ttgcgatctg aaatgagatc aagctggaaa tctgcattgg
    24361 tctgcactcc ttcaatctct aattcataga gggcacgttg cattttcatc aaggcgtcaa
    24421 aacgattttc gccgtgtact atgattttgg caatcatact atcataataa ggcggaatgg
    24481 tataacctgg ataaactgct gaatccacgc gcaagccaac tccaccactt ggcagataga
    24541 gattagtaat cttacctgga cttggagcaa agttaaaggc tgggttttct gcattgatac
    24601 gacactcgat ggcatgaccg cgtaggacaa tatcttcttg cttaacagac aaaggctgac
    24661 ctgccgcaat gcaaatctgt tccttaacga tatcaacacc tgaaacaaac tctgttactg
    24721 gatgttctac ctgaacacga gtattcatct ccatgaaata gaaattgcta cttgcttcat
    24781 caagaagaaa ttcaatggtt cctgcattct catagccaac aaactctgcc gctcgaacag
    24841 cagcagcacc tatttcatga cgcagcgttt ttccgattgc aatcgaggga ctttcttcca
    24901 aaaccttttg gttattcctt tgaagagaac aatcccgttc acccaagtga atcacatgtc
    24961 catgctcatc acctaggatt tgaacctcaa tgtgccgagc tggatagata acccgttcta
    25021 tgtacatggc accattgcca taattggcct tggcctcact agaggcagtt tcaaaggcag
    25081 aaacgaggtc atctggtttt tcaaccttac gaatcccttt accacctcca cctgctgaag
    25141 ccttgagcat aacaggatag ccaatttttt cagcaacaat caaagcttct tcagagttat
    25201 gcacttctcc atctgaacct ggtataacag gcacacctgc tttaatcatc tgagcacgcg
    25261 cattgatctt atcccccatc atatccataa catgaccaga tggaccgata aacttgatac
    25321 ctacttcttc acacatggtc gcaaatttgg aattttcact gagaaatcca aaaccagggt
    25381 gaatagcttc tgcctcagtc aagactgcag ctgatagaac tgcattaata ttgagataag
    25441 actctgttgc cttgccagga ccaatacaaa ctgcttcatc tgccaacagc gtatgaagag
    25501 cttccttatc agcagttgaa taaaccgcta ccgtcgcaat ccccaattca cgtgccgcac
    25561 ggataatacg aaccgcaatt tcaccacgat tggcaattaa aatttttcga aacatggaga
    25621 acctccttag ttcccaattg caaaagtaag ggtaccactg gctgcaagct tgccatccac
    25681 ttcagccttt gcttcaacca cagctatggt gccacgacgt tttacaaaag tcgctgtcat
    25741 aaccaattgg tcgcctggta caacttgctt cttgaactta accttatcca taccagcgta
    25801 aaagaccagt tttcctttat tttcaggttt tgataactcc aacacaccag cagtttgcgc
    25861 caaggcttcc ataatcagaa cacctggcat aactgggtat tgaggaaagt ggccgttaaa
    25921 gaaaggctcg ttgatggtca catttttgat agcaacaatg gtatcctcgc tcacctccaa
    25981 gacacggtcc actagaagca taggataacg gtggggaagg gcttctttga ttccttgaat
    26041 atcgatcatt tgatacgtac caatccttta ccaaactcaa ccatttcttc gttagagacg
    26101 agaatttccg ttaccacacc atccttagga gctgggattt cattcatgac tttcatggct
    26161 tcgataatta ccaatgtttg accttttttg acactatcac caactgtaac gaaggcaggt
    26221 ttatctggtc cagcagccaa gtaaaccact ccaacaagtg gactctctac aagatttccc
    26281 tcactagcca cacttgcttc agctggagct ggaacttctt ctgctacagt ctctgctgga
    26341 gcagatgtag gagctactgg actcggtgtt gctagaacgg gtgctggagc gacttgagtt
    26401 gcaacttcag gcacaggtct cgcttcattc ttgctaaact gcaactcatc cgtcccattt
    26461 ttataagaaa attctctcaa acttgactgg tcaaattgag tcatcaagtc tttaatatcg
    26521 tttaaattca tacttatcta ttctcccaac gtttgaaagc aagaactgca ttgtggcctc
    26581 caaaaccaaa agtatttgaa atagcgtatg gaatttcttt ctccaagcct tgtccataaa
    26641 cgacattagc ttcgatataa tctgatactt cacttgtccc agctgtcatt ggtacaaagt
    26701 tatgacgcat agcttcgatg gtgacgatag cttctactgc acccgcagcc cccagcaaat
    26761 gtcctgtaaa agacttggtt gatgatacag gtacttcctt accaagaaca gctacgatag
    26821 caccactttc tcctttttca ttggcaggag ttgacgttcc gtgagcattg acataggcta
    26881 cttgctctgg agaaatctca gcttcttcca aggctagttt gatggccttg atagctccct
    26941 gaccttctgg atgtggagaa gtcatgtggt aggcatcaca agtatttccg taaccaacca
    27001 cttcagccag gatagtagct ccacgttttt cagcgtgttc aagactttct agaaccaaca
    27061 tccctgaacc ttcacccata acaaacccat tgcgatcctt atcaaatggg atcgaagcac
    27121 gagttggatc ctctgtagta gagagagctg ttaaggcttg gaaaccagcg atggcaaaag
    27181 gtgtgataga agcttctgtt cctcccacca acatcacatc ttggaaacca aacttaatgg
    27241 agcggaaggc atccccaatc gcatcatttg atgaagagca ggcagtattg atagatttac
    27301 aaacaccgtt tgcaccaaaa cgcatggcta cattcccaga agccatattt ggtaaagctt
    27361 ttggaagagt cattggtttg acacgtttgg gtcctttttc atgaaggcga agtacctgat
    27421 cttcaatttc cttgattcca ccaataccag atgcaacgat aacaccaaaa cgatccctat
    27481 taagagcctc tacatcaaga ttggcatgat ttacagcctc ttgggctgca tacaaggcat
    27541 ataaagaata gttatcaaaa cggttggtat ctttttttac aaagtattta tcgaacggaa
    27601 aatcttggat ttctgccgca ttatgcacat caaagtcact atgatcaaat tttgtaatgc
    27661 caccaatgcc gattttccca gttgctaaac tattccaaaa ttcttctggt gtatttccga
    27721 ttggagatgt tactccataa cctgttacca ctactcgatt tagtttcatt cttttcacct
    27781 ctagctttcg ctacatactt aagccaccat caatggcaat cacttgacca gttagataat
    27841 cttggcctgc taaaaatact gtcaaatctg caacctgctc tgcctgccca aattctttca
    27901 tcggaatctg agctagtgta gcttccttaa tcttatctga taagatagct gtcatatcag
    27961 actcaatcat tcctggagca atcacattga ctcgtatatt ccgactagcg acctcgcgtg
    28021 ccacagactt ggtaaagcca atcaagccag ccttagaagc agcatagtta gcttgaccaa
    28081 tattccccat caaaccaaca acactagaca tattaatgat agcaccttct ctggctttca
    28141 tcatcggttt caagactgat tgtgtcatat taaaggcacc agtcagattg accttgagca
    28201 ctttttcaaa atctgcttct gtcatcttga gcataagagt atcttgggta atccctgcat
    28261 tgttgaccaa aacatctact gaacccagtt ctgcaatagc ttgatcagtc atacgcttag
    28321 cgtctgcaaa atctgataca tctcctgaaa tgggaaccac cttgatacca tagtttgaaa
    28381 actcagcgag caattcttct gagattgccc cacgactgtt taagacaatg ttggctcctg
    28441 cttgagcaaa cttgtgggcg atggcaagac caattccacg actcgaacct gtaataaaga
    28501 tatttttatg ttctagtttc atttttttcc tttcaaaact tctacttatt ttagtctatt
    28561 tttctaaaag tgctactaaa ctcgcttgat cttccacatg agctaagtga gcagtttgat
    28621 caattttttt aacaaaacct gacaagactt tccccggtcc aatctcgata aagttgctta
    28681 tgcctgcttc ttgcatgacc ccaatacttt catagaaacg aacgggttcc ttgacctgac
    28741 gcgtcaagag ctgagcaatg tcctcttttt gcatcacagc agcttctgta ttgccgacta
    28801 ggggacaagt aaaatctgaa aaacttacct gagctagagt ttcagctagt ttctggctag
    28861 caggctcaag gagagcggtg tgaaagggac ctgacacctt aagaggaatc aagcgtttgg
    28921 cacctgcttc ttgcaaaagt tcaaccgctc gatcaactgc aaccacttct ccagcaatga
    28981 cgatttgtgc aggtgtgtta tagttggctg gagtaaccac tccaagttca gaagcttttt
    29041 gacaggcttc ttcaatgacc tctactggcg tattgagaac tgctaccatc ttgccagagt
    29101 cagcaggagc cgcttcttcc atataggctc cacgcttagc taccaaggca accgcatctt
    29161 caaaatccaa ggcgccgctt gccaccaagg cagagtattc tccaagagac aaaccagcaa
    29221 ccatatcagg ctgatagccc ttttcttgca ataaacggta gatagcaacc gaagtcgcta
    29281 gaatggctgg ttgcgtatag cgggtctgat tgagtttgtc ttcttccgta tcgatgagat
    29341 aacgtaaatc ataaccgagc acctgactcg ctcgatcaat cgtttcttta acaatcggat
    29401 actgatcata gaaatcccgt cccatcccta gatactgggc accttgacca gcaaataaaa
    29461 aggctgtttt agtcatttct tacaactcct gcccagcgag aggcttcttc ttgaattttc
    29521 ttagcggctc cgtaatacaa atcttttagg atttcttcag ctgtttcttc tttagaaaca
    29581 agccctgcga tttgacctgc catgacagag ccaccctcca catcaccgtg aacaactgct
    29641 ttggctaggg cacctgctcc catttgttca aagatttcta aatcaggatc ttcctgctta
    29701 aaggcatctt tttcagccag ttcaaaatct ctagtcaact gatttttaat agcacgaaca
    29761 gcatgaccaa agtgctgagc tgaaatcgta gtatcaatat cccttgcttt taaaattttc
    29821 tctttgtagt ttggatgggc attcgactct tttgcaacta caaaccgtgt ccccacctgt
    29881 acagcctctg cacctagcat aaagccagcc gcagcacctt caccatccgc aattcctcct
    29941 gcagcaataa caggaataga tatagctgtg gctacctgtc gcaccaaggt catggttgtt
    30001 aatttaccga tatgcccccc agcttccatt ccttctgcaa taacagcgtc tgcaccgatt
    30061 ttttccatgc gtttagctaa agcgacacta ggaacaacag gaataacgat tatcccagct
    30121 tcatggaaac gttccatata cttgcttgga tttcctgctc ctgttgtgac aactttaaca
    30181 ccttcttcaa taacgagatc cacgatatct tccacaaagg gagataagag catgatgttg
    30241 accccaaagg gtttatcagt caatgatttg attttatcaa tattggcctt gacaacttct
    30301 ttcggggcat ttcccccacc gataattcct aatcctccag ccttggaaac agcccctgcc
    30361 aaatcaccat cagcaaccca ggccatccct ccttggaaaa taggatagtc aatcttcaat
    30421 aattctgtaa tacgcgtttt catagtgcct ccaaccttcc ttgcttacgt aatagttcga
    30481 tttcaccata atttgacagt caaactatta cctaaacaag agggagtggg tttctcccta
    30541 ctccttctac taatattctg cttattttgc ttgctcttca acgtaagcaa ccaagtcacc
    30601 aactgttttc aagtcatttt ctgcttcgat ttggatatca aaagcatctt cgatttctga
    30661 gattacttgg aacaagtcca atgaatctgc gtccaaatca tcaaaagttg attcaagtgt
    30721 tacttctgat gcgtcttttc caagttcttc aacgataatt tcttgtactt tttcaaatac
    30781 tgccatgata ggactccttt aaaataaata gtttttttat aacaatgtgt tcaccacatg
    30841 attacctaaa ttgtaagaat gagcgtgccc caggtcaagc ctccaccgaa gcctgataga
    30901 agaacagttt ggctaccatc taaagggatg agaccttgtt ctacacactc tgaaagtaaa
    30961 atcgggatac tggctgcact ggtattgcca tattccatca tattagctgg aagtttggct
    31021 cggtcaacac caatttttct agccatctta tccaaaatac ggttattggc ttgatgaagt
    31081 agcagataat ccaagtctgt cacctctata ggagattcat caatagtctg cttgatagac
    31141 ttggctacat ctcgaatggc aaaatcaaag actgtgcgtc catccatctt caaaaatgaa
    31201 tctgcacttt cttgatctga aaatggagaa tgcaaacctg aatgcccata agttaaacac
    31261 tcgctgcgac ttccatcgct attgagactc tcagctaaga aatgctcttg ctcgctagct
    31321 tctaacaaga caccaccagc accatctcca aacaacacag ctgttgatcg atccgaccaa
    31381 tcgactgcct tagagagggt ttcactacca atcaccaagc ctttttgaaa gcgaccagaa
    31441 gcgataaact tttcagcagt tgaaagagca aatacaaatc cactgcaagc cgcggttaag
    31501 tcaaaagcaa aggctttatt agcaccaata ttagcttgaa cacgagcagc tgtagagggc
    31561 atcatcgaat ctggagtaat ggtagctagg atgataaaat ccagttcttc tcctgttatt
    31621 ccagcttttg ccatcagttt cttagcaacc tctgtagcca aatcactggt agattctgtt
    31681 cttgaaatat gcctttgtcg tattcccgtt cgacttgaaa tccactcatc attggtatcc
    31741 ataatctgag ccaagtcgtg atttgtaacc acttgctctg gcacataatg agcaacctga
    31801 cttatttttg caaaagccat tatttcaaat cctccaaaaa ttggtaaaga ttagtcaaac
    31861 ctttacccat gacagcaatt tcttcctcgc tcatgccatc aataattttt tctaccatgg
    31921 ccttgtggaa gcgtttatgc agtctatgaa tcaagcgacc cttctttgtc aaatgcagat
    31981 gcaccacacg acgatcctgt tctgaccgaa ctcgctcaat gtagccctta cgctctaaat
    32041 tgttcaaact tgtcgtaaca gttccaagag ttaccatcaa ctcttttgac acttgacttg
    32101 gagtcacatc tggagcctta ccgatgacat caatcgtatg catttctttg atggagatat
    32161 ccttaaaacg actacctctc aagttcactt cctcaattac aaggacattg ttaaatatag
    32221 atgttaaata ttcattgatt cgttggtagt ccatttttca tatccctcct tcttcaaaaa
    32281 acttttacaa tcaaaacatt tgacagaaag aattatatca aaattcaaag aatgatgcaa
    32341 gtatttttta ttttcctgta aatttaggtc ttcttctctc cgaatgagct cgcactcctt
    32401 ctttgaaatc ctctgtttga gctaaggatt tctgtaggtt cagttctaaa gtagcgtaac
    32461 cctgccagtc tttaaattgg ctctcccaaa ccaacttctt aatggcagca taggaattac
    32521 ttgaagcacg tcttaatttt ttaagaagct gttctctcgt cttttcaagt ttttcagctt
    32581 cagaaacgcg gtaaaccaac ccccattcta gggctttttc tgccgttaaa gcctctcctg
    32641 tcatagctaa ttgagcagca cgcgtcacac cgatactgcg gctcaagaga tgaattcccc
    32701 ctgcatctgg agccaaacca acaccaacaa aggcttggat aaacttagcc ttatccgtcg
    32761 ccaaacagaa atctgccgca acagccatat tcgctgcggc acctgcaaca gcaccgtcaa
    32821 cttccattaa aacaggtttg gctatttgct tgattttata agaaatcgta ttgaccaact
    32881 ctgcgatttt tgtcaatgat ggaatatcat cctcatccac tgcccgcttc atctctacca
    32941 aatctccccc aactgagaag acctttccat tggcattgat taagataaaa tgcacagctg
    33001 gattttcttc tgccaaagtc agagcttcta aaatctcctc acacatggga atatgaaaac
    33061 catttgcgac ctcaggacgg ttcaaggtaa ggattgccaa gtcctcttca agctgataaa
    33121 taatgtgttc catcagggct cctttttatt ttataagcag tttatactct tcgaaaatct
    33181 ctttaaaccg cgtcagcttc catctgcaac ctcaaaacag tattttgagc tgacttcgtc
    33241 tagcttctta gtttgctctt tgattttcat tgagtgttaa attatttcac tgtcaaagta
    33301 tatctttttt aggagcagaa agcaagaaaa aatcgactga aagtgtctca gccgataaga
    33361 aaggctcgct ttaggctaga aagcatctta ttttcttcat tgaaaaaagc ctttctttct
    33421 gctataatcg tataaaatac ttactttagg agttcttatg aaagttgtta aatttggagg
    33481 tagttctctt gcctctgcta gtcaattaga aaaagtttta aacatcgtca aaagcgattc
    33541 agagcgtcgt tttgtagtcg tttctgcgcc tggtaaacgc aatgctgaag atactaaggt
    33601 tacggatgcc ctgattaaat actaccgcga ctatgttgcg ggtaacgata ttagcaagag
    33661 ccaaagctgg attatcgacc gctatgctgc tatggttagt gaattgggac taaaaccagc
    33721 tgtgctagaa aaaatttcta aaagcattca cgccttggcc actcttccta ttgaagaaaa
    33781 tgaatttctc tacgatactt tcctagcagc cggtgaaaat aacaatgcca aattgattgc
    33841 tgcctacttt aaccaaaatg gtatcgatgc acgctatatg caccctagag aagctgggat
    33901 tgtggtcaca agtgaacctg gtcacgctcg catcattcca tcaagttatg acaagattga
    33961 agaattgaca aacaccaatg aagtccttgt cattcctggt ttctttggtg tcactaagga
    34021 aaatcaaatc tgtactttct cacgtggagg ttctgatatt acaggttcta tcattgctgc
    34081 tggtgtcaaa gctgacctct atgaaaactt tacggacgtt gatggtatct ttgcagccca
    34141 ccctggtatt atccaccaac cacactcgat tcctgagttg acctaccgtg aaatgcgcga
    34201 gttggcctat gcaggcttct cagtccttca tgacgaggct cttcttcctg cctaccgtgg
    34261 aaaaattcct ctggttatca agaataccaa caaccctgac catccaggta ctcgtatcgt
    34321 tctaaaacac agtaatgatg aatttccagt tgtgggaatt gctggtgact caggctttgt
    34381 cagcattaac atgtcgaaat acctcatgaa ccgtgaggtt ggatttggcc gcaaggttct
    34441 gcaaatcctg gaagaactta acatcggttg ggaacatatg ccaacaggta tcgacgatct
    34501 ttctatcatt ctccgttctc gccaactaac tcccatcaag gaagaagaaa tcctgcgtca
    34561 gttggttcaa aaggctaaag tagatcatgc agaaatcgaa cacgaccttt ctatcattat
    34621 gattgttggt gaaaaaatga agagccatat cggagtgact gctactgcga cacgcgctct
    34681 atctgaaaac aaaatcaaca tccagatgat gtctcaaggt tctagtgaag tttctattat
    34741 gtttgttgtc aataaagacc aagagaaagc agcaattaaa gccctctaca atgccttttt
    34801 tggagaaagt aaggaagact aagcatggcc caatcactta acaaaacagt actcctcagt
    34861 acgacaggca cttcctacct ctctatcgct gggaaagttg ggaaattcct tgtcggagat
    34921 caggctttgg aattttaccc agatgtcaat gtcgaacaat ttatccagat tccttggagc
    34981 catatcaatc agattggagc caatgtcact ggacgcaaaa tcagccgcca cttcgaagtc
    35041 tttacagaca aaggaaaatt cctctttgct tcaaaagact caggtgccat tctcaaaatt
    35101 gcacgcgaaa aactaggcaa tgacaaggtc gtcaaacttc cgaccctgat tcagacaatt
    35161 agccaaaaat ttaaaaatct atttgcaaaa aagtagaaac tttagtataa tcatagcaac
    35221 ggataagtag gttatcttct tctttcagaa agtctgcggg tactgcgagc agataggggg
    35281 gataggtgaa attctaccgt tagtaacaat tacatacaca atcaagtgca cacctgtgaa
    35341 gttggatgga accgtggccc tgccactcca acgttttgtc aggcgtgctt ttttcataaa
    35401 ggagttctta tgttagatat caaacgtatt cgtacagatt ttgaagctgt cgcagaaaaa
    35461 ttagctacac gtggtgtaga tgctgctgtc ttgaatgaaa tgaaagaaat cgatgctaaa
    35521 cgtcgtaaca tcttggtcaa ggttgaaact ctcaaagcag aacgtaacac agtttctgct
    35581 gagattgccc aagctaagcg caacaaggaa aatacagatg acaagattgc tgccatgcaa
    35641 aatctatctg ctgaggttaa agccttggat gctgaattgg cagaaatcga tgctaaattg
    35701 acagaattta caacgactct tccaaatatc ccagctgaca gcgttcctgt tgggactgac
    35761 gaagacgaca atgtggaagt tcgccgttgg ggtactccac gcgagtttga cttcgaacct
    35821 aaagctcact gggatctcgg tgaagacctt ggtatccttg actgggaacg cggtggtaag
    35881 gtaacaggcg ctcgcttcct cttctataaa ggcctcggtg ctcgtttgga acgtgctatc
    35941 tacaacttta tgttggatga acatggaaaa gaaggctata ctgaagtcat cacaccttac
    36001 atagtcaacc atgattctat gtttggtact ggtcagtatc caaaatttaa ggaagatact
    36061 tttgaactca gcgataccaa ctttgtcttg attccaactg ctgaagttcc tctgacaaac
    36121 tactaccgtg atgaaatctt agacggcaaa gatcttccaa tctacttcac tgccatgagt
    36181 ccgtcattcc gttctgaggc tggttctgcc ggtcgtgata cgcgtggctt gatccgtttg
    36241 caccaattcc acaaggttga aatggtcaaa tttgccaaac cagaagaatc ttacgaagaa
    36301 ttggaaaaaa tgacagccaa cgctgaaaac attcttcaaa aactcaacct tccataccgt
    36361 gtcgttgctc tctctactgg agatatgggc ttctcagctg cgaagactta cgacttggaa
    36421 gtgtggattc cagcacaaaa caattaccgt gaaatctcaa gctgttcaaa cacagaagat
    36481 ttccaagccc gtcgtgccca aatccgttac cgtgatgaag cagatggcaa ggtgaaactc
    36541 cttcatacct tgaacggctc tggacttgca gttggacgta cagtggctgc aattcttgaa
    36601 aattaccaaa atgaagatgg ttctgtgacc atcccagaag cacttcgtcc atacatgggt
    36661 ggagctgaag tcatcaaacc ataaaaaata aggtttagct atttctagct agaccttttt
    36721 tcgtaaccaa atcagataag cacctagtac aaagaataaa atagttaggc atataatggt
    36781 ttcagccaat accaggtaat ccagaaatgg aagtttcaaa attccctgag ccatcttgag
    36841 cgaggtcgct gtgataatgg ttgggaaggt gagggctgag agggctggtt gaaaaccttg
    36901 ttttaaaatg ttgggcagac gagttaaaac aaagaaaaag aaggattgag aagccaaaat
    36961 catgacaatc aagacccaag tcggcaggct ggttcctcct actcgaacta gagaagccaa
    37021 gagtagagag aaaggagcac agtagattcc ttcttgtcca agcaaggcta gtgggagtgg
    37081 atgtttcttt aaatcgctat aaataagggg atagagatag aaggtcaaga gaaaaccaaa
    37141 actcaaggtc gcataggcaa tttcgataat acctaccaga ggataggtca aggcagccac
    37201 tgctatcccc acatagagaa ccgtccaact tggagtggca tgaaccctcc gccctgaaca
    37261 agcaaacttg atggtaaaac cagcaatcaa ggtcaaatcc aagagaaatg aaaaccacca
    37321 aatcccttgt gctaccaaag gaagataaga gaatacgcga aagacatagg tcgataaaat
    37381 catcccagcc ataggaaagg ttgccattcc tgacaaaaga gggggcttgg tcaattcttg
    37441 cttggtttct ttccaattaa agagatgcag aattagaaag taaatccata aaaccaaacc
    37501 agtcagacta aaaagatggg atagaaccgg caacgtatct aaaataagat ttccagctcc
    37561 tgccaaacct agcaaacaac ctgaaaatac taaggggagt tttttcatcc taacctccaa
    37621 taatcatgtt agtttcagta taacataaaa gcgcttaaat gaggatttaa aaaaacgaag
    37681 tccgcttatt tcagacttca ttttactcag atatgaatta ggcataaggt tgcaattctg
    37741 gattaattgg tgtattagct aagttgttgg catagttaca gaggattgct aggctgacac
    37801 caaaaaccac atccaaggca ttttgttgag tgtagccagc ttctaaaaac tcagacaagg
    37861 cttcatctcc tacacgaccc ttggtattga taactgccaa ggtaaactta gctagggtat
    37921 ccaatttagg atctgtttca attggagtac gattgcgaag agcttgaatc aagtcatcat
    37981 tcatctggat ttgtttgatg gaaaaggctg tgtgacctgc gacacagaag gcacaaccat
    38041 tggtcacggc tgccgtgatt tgcaccactt cacgctcaac gggtgtcagg ctgttgcgac
    38101 ggtggataga tgagacaatt tggtaggctt ctaaaacagt cggggcattg gccaagagac
    38161 cgattaggtt gggaatatag ccattgttgt ctttttctac tgtttcaaga atttctttca
    38221 cttctgctgg tgctgactct actgtatgga tagtaaatgt tgtcataaga tacctctttt
    38281 cttattattg acactaatat tattggaaaa tcttataaaa tcctgattcc taagtttatc
    38341 taagataaag ctttattctc tcataagatt ttcgttgtta tattagttta tcacacttcc
    38401 aatcacttgc ataatatata ttatatatca ggctgataaa aattatttat aggcaaaaaa
    38461 atcacacgag ctgtgtgatt ccattatttg tcaaaatact ttttagtttc agcaataacg
    38521 actggcgaca agaccaagag ggcaatcaag tttggcagag ccatcaaggc gttaacgata
    38581 tctgcgataa tccagaccat atccaactcg ataaatcctc ctaacaagac catgagcaca
    38641 aaaaacacac ggtagagcca gataaagcga gccccaaaga ggaactcaaa acagcgttct
    38701 ccgtaatagt tccaacctag aatcgttgta aaggcaaaaa gtacaaggaa gatggtcaag
    38761 agggcaggcc caaagtgtga aaagactgtt gagaaagctg actgagtcaa ggcaacccca
    38821 ttcaagtcac cactccaaac tccagttacc aagatggtca aaccagttag agtacaaatg
    38881 atgagggtat caataaaggt tcctgtcatg gaaatcaaac cttgctctac tggttcattt
    38941 gtcttggcag ctgcagctgc aataggagca gaacccagac cagattcgtt tgagaacaca
    39001 ccacgcgcca caccattttg aatagccatc cgaacgctag caccagcaaa tccacctacc
    39061 gcagcaaggg gactaaaagc tgaggtaaag actaaagcga ttgtgccagg gatttttccg
    39121 atattaaaga aaataactgt aagagttcct aagatataaa tgagggccat aaaaggaaca
    39181 acagtagttg aaaccttaga aatagacttg agtccaccaa agactgcaat cgctacaaag
    39241 acagacaaga cgagagctgt gatggctggc gaaatcgtcg ttgtattttg gatagattct
    39301 gtaatcgagt tgacttgggt gaaggttccg attcccaaga gagcaaccaa tactcctgct
    39361 actgcaaaca aaacagcaag tggtcgccac ttttctccca tccctagaag gatatagtgc
    39421 atgggacctc ccgctactgc accatggtcg tccttggtgc ggtatttgat ggccaagagt
    39481 ccttccgcat acttggtagc cattccaaag aaagccgcca tccacatcca aaatagagct
    39541 cctggtccac caaccttgat agccgtcgca actcctatga tatttcctgt tccaacagtt
    39601 gatgccaagg ctgtacacag agctgcaaaa ctggatacat caccatgtcc cttatcctgg
    39661 ataaaaataa gctgaaaggc cttgggcaga cgcaaaacct gcaagagtcc tagccgcatg
    39721 gttaggtaaa tccctgttcc gaccaataaa atcaagaggg gcggtcccca agcaaaagca
    39781 tcgattgatt taagcaattc taacatttcc ttctcctatc gtttcaaccc caaaagaaag
    39841 agcacatgca agatacatgt actctggaat gcttagataa atgctaaaaa gcggtctatc
    39901 ctagctctgt ccttttacct gagagtttga gcagttgcct gccttgcccc ttcggtgcct
    39961 ttacggtctc tccagagttc cgtccattta cagtcatgga aaatcaaacg attccccact
    40021 tctattaaac ttcattcggt gttggtattt aattgattct aattttacaa aaaatgttgg
    40081 cttttgtcaa tgtgtttatt agtaaaaatt agttcaacag tttttacttt ataaagtcca
    40141 gaatactgct atcctttaaa agtgacaata gtcgcaccac tgcctccagc attttgtggg
    40201 gcatagccga aactcttgac atgtttgttt ctttgcaagt atttggtaac tccttcacgg
    40261 atgactcctg ttccgatacc atggatgata tcaacttgag ccatattgtt aagcaaggct
    40321 tggtcgatga aggtatctag ctcattcatg gcttcttcat agcgcttgcc tcgaagatcc
    40381 agtctagctt gaggtcctcg cccagaagtt cgtttcacaa cattgacctg tttcttcttg
    40441 actggttttt cttgctgggc ttgaacaaga tcaaactctt tctcttccaa ggtcatctta
    40501 atcaagccaa cttgggcttc ccagcgaccg tccttgagtt gactggtcaa ggtaccacgc
    40561 tgaccataac tgagaaccac gatatcatct cccacctttg gagctcgttt tttcttggcc
    40621 ttttgaagga ccttattttt agacaagtcc actttttcag gagccaattt tttcaacttg
    40681 gccttggctt caatgatttc gtggggcttg agttgggatt tactgtggag atttttgaga
    40741 atctggtcac tttcacttag ggccatatcc acaatctcag cagcctgttc acgcgccttg
    40801 ttaagctcgg tttccttttc acgattaagc tcgttgtaga gtttttttag cgcacggttc
    40861 atcttgagat tttcttgctc cacctcacgg atattgtcca aacgtttgcg gctttccagc
    40921 gtctgctctt ctaattgctc aatgatacga ttgacgtcat tgtcctgatc gatctgctga
    40981 ctggcatctc ctacgataac ttcagatagg cctagacgtt tggcaatttc aaaggcatta
    41041 cttcggccag gaacaccctg cataaagcga taggtcgggc gaagagttgc agtatcaaac
    41101 tccatactgg cattttgcac aaaggctgtc tcaataccgt aggccttgag ttctggatag
    41161 tgggtcgtcg ccatggtctt gatttgacgc aggcgaaggt cctccagaat agccatggca
    41221 agggctgctc cctcttgggg atcagtacca gcccccaact catccaaaag taagagtgaa
    41281 tgttggttga ccttgccaag aatatccacg atattggtca tatggctaga gaaggtagac
    41341 aagctctgct caatagactg ctcatctcca atatcagcaa agatttcttc aaaaatacca
    41401 acacgacttc ccttgtctgc taaaatcggc aatcctgact gggccatgac ctgtgtcaag
    41461 cccagagttt tgagcatgat ggtcttccca cctgtattgg gacctgtaat gacaatagct
    41521 gttaaatctt gaccaaaatg gacatcattt gcgacggcat ttttgaccaa aggatggcag
    41581 acatggagca gttgaatctc ttgattttct gacagctgag gcacgactgc ttgtctttct
    41641 tggataaatc gaaccttggc acgaatcaag tccagatgac cgataatcca agcgtcatta
    41701 gcaatctcag ccgcatgagg gcggacacgc tcagaaattt cttggagaat gcgaagcatt
    41761 tcatagcgct catctgctcg cagactagca atttcttcgc tcagtttgac tacctcacgt
    41821 ggttcgatat agacggtgtt tccactagca gaaatatcat gaacgacacc tgcaatctta
    41881 ttgcggtagg tgtttttgac tggtaaaacc tgacggccat ttctgctagc aacaattcct
    41941 tccgtcaaca tctgcgcttt ttgcttgagc aagtcttgta aaacatcgcg tacctgactc
    42001 tcgctatcat gtatttttcg acggattcgc gccaattctt cactggcaaa attttcaatg
    42061 aaacccgcat cattaaaggc ctgaagattt ccttgtaatt gcggaaaatc atgtaatttc
    42121 tcaaaccaaa gggctaattc ttccaagctg acattttcca gattggcata aaaactttga
    42181 agttctcggc tggcaagaag cacgcgtttc aagagtagga actcctcgat attgagatcc
    42241 gctcccatct ccaacctctt gcagactcct gcaatttcct tagttgagag aatagtaaaa
    42301 tgcggttgct cgacgaaaag agcctgcatt tctttcatct cagcaaaagc ctgtttgatt
    42361 ttatctgctt tggcagtcgg agccagctgt ctcaattgct ccaagccctg ctcggtcaac
    42421 aaatgaggat caaacaaggc cttgacctta tcgaactcta atgtttctaa tattttctta
    42481 ttcatcttta tttccttgtc tttgaatgtc taggtgtggt agctttttac attctgatag
    42541 attcgagtca aatctgtaaa caaagggcta ggaaaactcc tgcccttttt atccgattaa
    42601 atttgtcacc cagatttgtt tgagccaact ggttgttatc ggtatgctct ggatgatgtg
    42661 ttttgcgacg atactctttt caagaggatt ttgtataact gccatgggga tggtcgccaa
    42721 gattgtcaag gccatttgca agacaaataa ggtcaccaac atggacaaga tacctgctga
    42781 aacttggaac aacttaccac ccagtttttt gctaggaatc aagtgtaaga gaagaccaag
    42841 caaacgacca atgctataga aaatcccaaa tacaagcaag tagccgatac ctgcataaaa
    42901 gaccttatcc agctgaaaga gttgatccga tgggaaaaag aaagtcccct gaccttcctg
    42961 cgaatttgca taagggagca ataaatggaa ttgctctcca agccccttat aaaactggcc
    43021 agccataaaa gccgatgcca tggctgaaat caggtaataa acctgtaaga gcaggcctct
    43081 ccgatagccg atataaaatc cccaaaccaa gaccaataga agaaggaatg aaatcataag
    43141 gaatcctcaa tcttgctctg ttcttgctta caagtcacaa gcttgtgacg gagttcttct
    43201 agctcttgct ccttatcgtc aaattcaatc tcacggctga gctgagttga taaacagttg
    43261 actgccaaca aaagagcgat tgtttcatca tctgcgctag gcatttgttc tttaattgct
    43321 tggtattttt ctgtcgcaac cttagcgatt tcctccataa aaaggttatc atgttcgctt
    43381 gtcaaggtta acgatttttt cccgaatgta aatttgaatc gatttagatt tgccataaaa
    43441 ttcacctcac gatattatac caaaattcgc taattttgtc agtttttaca aattttactg
    43501 cttttgtggt acaatagaaa ctatggcaag tatcacactc acaccaagcg aaaaggatat
    43561 tcaggctttt cttgaacact atcaaaccag tctggctccc agtaagaatc cctatatccg
    43621 ctactttttg aaactacctc aagcaacggt ttctatctat acttctggaa aaatcttgct
    43681 tcagggtgaa ggggctgaga aatacgctag tttctttggc tatcaacttg tagaggaaaa
    43741 cagggggcaa aatcttcctt taattgggac agatgaggtg ggaaatggtt cctactttgg
    43801 tgggcttgca gttgtggctg cctttgtcac atctgaccag cacgactttt tacgaaaact
    43861 cggtgtgggg gattctaaga ctctgaccga ccaaaagatc cgtcagattg ctcctattct
    43921 caaggaaaaa atccagcacc aggcactcct tctctcaccc agcaagtaca acgaggtcat
    43981 cggagaccgc tacaatgctg tttcggttaa ggttgccctc cataatcagg ctatctatct
    44041 cctccttcaa aaaggtgttc agcctgagaa aattgtgatt gatgccttta ccagtgctaa
    44101 aaattatgac aagtacttgg cacaagaggc caatcgtttc agcaatccta tcagcttaga
    44161 agaaaaggct gagggcaaat acttgtctgt cgcagtttct tctgtcattg cgcgtgatct
    44221 ctttctggaa aatcttgaaa atttgggacg agaactgggt tatcagctcc caagtggagc
    44281 tggaacggct tctgacaagg tggctagcca gattttgcaa gcctatggta tgcagggact
    44341 cagcttctgc gccaaattgc actttaaaaa cactgaaaaa gcgaaaaaac gcttagaaag
    44401 gtaagttatg aattcattta aaaatttctt aaaagagtgg ggattgttcc tcctaattct
    44461 gtcattacta gctttaagtc gtatcttttt ttggagcaat gttcgcgtag aaggacattc
    44521 catggatccg accctagcgg atggcgaaat tctcttcgtt gtaaaacacc ttcctattga
    44581 ccgttttgat atcgtggtgg cccatgagga agatggcaat aaggacatcg tcaagcgcgt
    44641 gattggaatg cctggcgaca ccattcgtta cgaaaatgat aaactctaca tcaatgacaa
    44701 agaaacggac gagccttatc tagcagacta tatcaaacgc ttcaaggatg acaaactcca
    44761 aagcacctac tcaggcaagg gctttgaagg aaataaagga actttcttta gaagtatcgc
    44821 tcaaaaagcc caagccttca cagttgatgt caactacaac accaacttta gctttactgt
    44881 tccagaagga gaataccttc tcctcggaga tgaccgcttg gtttcgagcg acagccgcca
    44941 cgtaggtacc ttcaaagcaa aagatatcac aggggaagct aaattccgct tctggccaat
    45001 cacccgtatc ggaacatttt aagagaccta agaggccgag aatcaccaat ctcagcctct
    45061 tcttctatcg tgagaagtga ttgtttattg acaaatactc aacgaaaatc aaagaacaaa
    45121 ctaggaagct agccgtaggc tgcttaaaac agtgttttga ggttgtggat agaactgacg
    45181 aagtcagctc aaaatactgt tttgaggttg cagatggaag ctgacgtggt ttgaagatat
    45241 tttcgaagag tataaaataa aaacaatccc aactctcacc tattcatgca aaggaatttt
    45301 atggaagttt atttttcagg aaccattgaa cggattattt ttgaaaatcc cagcaatttt
    45361 tatcgcatcc tcctcctaga aatcgacgat acggacgcag aggattttga tgattttgaa
    45421 atcattgtca caggaaccat ggctgatgta attgagggcg aagactatac tttttggggg
    45481 caaattgtcc agcactccaa gtatggagaa caactgcaaa tcagtcgtta tgatcgcgca
    45541 aaaccaacta gtaagggctt ggtcaagtac ttttcaagta gccatttcaa ggggattggt
    45601 ctcaagacag ctcagaaaat cgtggatacc tatggcgaaa ataccattga cgaaattttg
    45661 caacacccag aaaagttaga aggcatcgca ggactctctg ccaaaaatcg cgaggctttc
    45721 gtctccactc tccgtctcaa ctacggaacg gagatggttt tgtccaaact agccaactac
    45781 ggcattccca acaaactagc ctttcagatt caagactttt acaaggaaga aacccttgat
    45841 gtggttgaaa attatcccta ccagctggtt gaggatatca agggtttggg ctttaccatt
    45901 gctgaccaac tagctgagga actaggcatc gaaagtcagg ctcctgaacg cttccgcgcc
    45961 ggtctagttc acagtctttt tcaggcctgt atggaaacag gggacaccta tgttgaagca
    46021 cgggatttgc tggaacaaac ccttactctc cttgagtctt cccgtcccgt ggaactagac
    46081 cccagccaag ttgcccaaga gctctcctac ctgatcgaag aagacaaggt tcagcagatt
    46141 gataccaaga tctttgacaa cagcctcttt ttcgctgagg aaggcatccg cagtcacttg
    46201 gttcgtatcc ttgaaaaagg aaaacagaag agtcatgatt tagaaaccat tcaaaaacat
    46261 atcactacta tcgaggaaga gctgggaatt gagtatgata acattcaaaa acaggctatc
    46321 tgtgatgcta tccagaataa ggtctttatc ctgacaggtg ggcctggtac tggtaagaca
    46381 actgttatca atggaatcat cgctgtttat gccctgttag agggacttga cttcaggaag
    46441 aaaagcaatc tgcctattct tcttgctgct ccaactggtc gagctgctcg tcgcatgaat
    46501 gaattgacag gtttgcctag cgcgaccata catcgccact tgggaatgac aggtgacgat
    46561 gataccagtc atctggaaga ttacctagat gctgacttta tcatcgtgga tgaattctct
    46621 atggtagata cttggctggc caatcaactc ttctccaata tctcttctaa cagtaagatc
    46681 ctcatcgtag gtgacagtga tcagctacct tctgtcagtc ctggacaggt tctagcggat
    46741 ctgcttcata ttcctttgat tcctcagact cacttggaaa aaatttatcg acaaagcaaa
    46801 gaatcaacca tcgtcaccct agctagtcag attcgacagg gcatcttgcc agctgatttc
    46861 acccaaaaaa aagctgaccg ttcctacttt gaaattgcta gtggccatat tcctgccacc
    46921 attgaaaaaa tcttaggtgc cgccctcaga aatggtattc ctgcccgtga tatccaagtt
    46981 ctggctccta tgtaccgagg gacggcaggg attgatgcta tcaatcagct catgcaagac
    47041 ctgctcaatc ccccacaaaa agatcaactc agttttgaag ctcctcagtg ccactatcgt
    47101 aagggagaca aggtcattca tttggttaac gatgctgaaa tcaatgtctt taatggggat
    47161 ttaggagcta tcacagacct gattcctggt aaatacaccg aatcgaaaca agacgagatt
    47221 gtcattgatt ttgatggtaa tgaagtctct tacccccgta acgaatggta caagattcgc
    47281 ttggcctatg ccatgagtat tcataagtct cagggaagtg agttcccagt tgtcatccta
    47341 ccgattacta gtgctagccg acgtatgctg gagcgaaatc tcatctacac agccattaca
    47401 cgtgccaaaa gcaaactcat cttactaggc gaattacaag ccttcgacta tgctacccaa
    47461 cacatcggaa ctgcccgaaa aacctatctg attgaacgct tcagtgatct actggagaat
    47521 gttgaagaaa agcaacaagc tgtctctgaa acagtcacat caagtgcctc tgaacaatcc
    47581 tacatcctaa ccgaagaaaa ctgggacagc attccagcca tgattgggat tacagacaca
    47641 gacctcaaag agatttttgg aaaatagtgc atcagaaaaa ccaccaattc aggtgggttt
    47701 tctgtttatt aagattattt tactgttgct gtgcttgtaa tcaattcaac agcttttttg
    47761 atagtgatat catgtttcaa catgtcagct gaaagcaagt tttgaacttg tgcaacttcc
    47821 atgttgtagt ctgctgccaa ttgctcaact tctttttgga tttcttcttc tgaagcatca
    47881 aatccttcag ctttggcaac tgcttcgata acaaggttag tcttagtacg tgactcagct
    47941 tctgcttggt attggttgtg aaggtcttct tgagtagttc cagtaatttg gaagtacatg
    48001 tcagggttga tcccttgacg ttgcaagttc ccaaggaatt catttactga acggtgaact
    48061 tcttcgtgga tcatttcttc tggaagttct acgatttcag cattttctac agctgtatca
    48121 attgctgcac cttcaactgc atctttgtaa gcttcttctt tagcagcagc caattctttg
    48181 cggtattttt ctttcaagtc agcaagtgtt tcaacttctt catcaatgtc ttttgcaagt
    48241 tcatcgtcaa gagctggaac ttctttagct tttacttcgt ggatagttgt cacgaattta
    48301 gcttctttac ctgcaaggtc ttctgcttgg tagtcttctg ggaatgttac gataacatca
    48361 acggtttcgc cagctgagtg acctaccaat tggtcttcga aaccagggat gaattgacct
    48421 gaaccaagtc caagtgagaa gttttcacct tttccaccgt caaattcaac accgtcgata
    48481 gaaccaacga agtcgatcac aacagtgtcg ccgtcttcag cagcagcttc cttgataacc
    48541 aattcagcca ggttgttgcg ttcacgttcg atacgctctt cgacatcagc gtcagttact
    48601 tctttttcta catcaactga tacttcaagg tttttgtagt cacccaattt tacttcaggt
    48661 tttgtaacaa cttcagcagc gataacccag tcttgacctt tttccattga agttacgtca
    48721 atttttggtt gggcaaccac ttcaagacca gcctctttta cagctgcttc ataagcgttt
    48781 ggcaaaagag cgttcataac gtcttggtaa agtgattctt caccaaattt tttatcgaag
    48841 ataggacgtg gaaggtgacc tttacggaaa cctggaacat taagagattt cttcactgac
    48901 ttgaagacac ggtccaattc tggtttgatt tggtcttgag agatagtgaa agtcaagaca
    48961 ccacggtttg tttctttgtt ttcaaatgat acagacattc tgtcatttct ccttaaaatt
    49021 ttttaaatac agtctattat aacattttct ataaataaaa tctagactaa tgcagacaat
    49081 tatagacaac aagccttttt cctaactaaa acactcataa agtatagaca attttagact
    49141 actttggata tcttttggtt agtcattttc caaaactaat ttatctaatt tttaagttat
    49201 atttgacttc atcttctcag taacatgagt ataaacactt aaaatctttg tttcattagt
    49261 ataatctaca cgatccatta tcgctgttat aggtacttcc aattcagcaa gcaaacttat
    49321 atgcgaatat ctaaaaacat gagcagtcaa tacaaaatca tctttcttaa tttcactttt
    49381 cctaaacctg tttttcaaaa agtaattgaa acaagttatc attaagggag aaccattatt
    49441 tgtaaatata taatcacctt cttctaaaag aagatattct tttaaaattt ctaacactct
    49501 atcactaata ccaattactc tatatgaagc taaacttttc ggactatcca aaaacacttc
    49561 gttattggac gattacatta tagtaaaacg aaataagaac aggacaaatc gatcaggaca
    49621 gtcaaatcaa tttctaacaa tgttttagaa gtagaggtgt actattatag tttcaatcta
    49681 ctatacaaga cgaaattgaa gaaatctttc cattataaaa cgcatattat caaggttttt
    49741 aaacacctaa taatatgcgt tttttcctat tttaaagact tttatccacc tattatacaa
    49801 agttaagtat ccatcacagt ttacaattag ccttcattac ctaacccatt caccatcctt
    49861 caagagagta acctttaaga accgaataaa taaatggcaa atttcgttca tttaatttaa
    49921 ctgcactgtt aatttgatta gctccatctc ctaaagtatg cactcctact acacggtgac
    49981 tagcatcata aactgtagat ccactagacc cctctaaagt atcaacttgg taatccaaga
    50041 acatgccatc atcacttaaa acttgttttt tatctgtata catttgatga actttaaaat
    50101 tatatgatgg atagcctgtg atagtcacag ttattcctgt caaatttttt tgactagtag
    50161 gaagacccaa agtccctaat tttgcaccaa tgggctcttc tagaattaat aaagccaagt
    50221 catattccct tgcatcctta gaatttaaat ttctaaattc cttcaaataa cgaacttcct
    50281 ttactttgat ctttccaaat ggttcttgac ttggactaac agtcggaaga acataaatat
    50341 catccgcttc tttcccatag tcatgtctgt agtagttgtg agccgctgta attaacacat
    50401 tatctttaat aaaattcgca cttcccctcc cttctacatt cattccatcg gctactccat
    50461 aatacttaga taaaaccata gctgaagtcg aatacggata ctgtaaagta ttatcaattt
    50521 taatcaaatc atcattaccg ataatacttc tgattgcttt tggtagtatg aaccatatgt
    50581 tggtgaaatc tcagataatg aagaatcatt agatcctgga cctttttcta gtgtctcact
    50641 tacctcatat tcttcacccg tactagaaat aacactcaaa gcagatactg tcgataactg
    50701 gctagccaat aaagtactcg caataattga aatacccaat tttttataaa cagttttctt
    50761 cattattgta tcctcctaat gtaattatag cgtactattc taaatttctt aatctactat
    50821 agaatcaaga aatctaccac cttctttaaa taccctccat tatcacataa acaggtaaac
    50881 ttttcaatta atgactgcgc ttttcaatca cgctagaggt acttacttgc ttctttgata
    50941 ctaagttcag ccattctttc cttgtttttc tcaataaagc atgttaccca agtgggattc
    51001 gttttggagt agtctcgcag agtccagcca atggctttat tgataaaaaa ttctgtttgg
    51061 ttcaagttat gaagtagaat cttttccatt aattgagtat tggtcttctc ttttcttaac
    51121 aactggtggt caatagcgac acgtctcagc cagatattat ctgataggct ccattttata
    51181 ctcaatgaaa atcaaagagc aaactaggaa gctatctgca acctcaaaac actgttttga
    51241 ggttgcagat agagctgacg tggtttgaag agattttcga agagtattaa gattatttct
    51301 tctagttcag ggtgttcata caccaaactc cctactactc gatctaggat atctaccgtg
    51361 tcccaccagg attttgtcac gactaactgc tctagcttag gcaaatcggt ttcctttaga
    51421 taagactgca ttgctttcaa atagttagca gccacatatt ggtattttct aggctccttt
    51481 tcccagcaag tgtctgcaaa atcccaatcg ataatctttg tttttttcgc ttctggtaaa
    51541 tatttttata gagtttattt ctttcaggca ccgcaatacc tagaaaagaa aattgatggc
    51601 gcatataggc ttccatgggc cttgcttttt tagagtcttt tgctgcttct agctcctcaa
    51661 gtaaatctgc taaactcatc taaaactcct cttgccccac caaatggtgc tgaaaggcat
    51721 agacagccgc ctgggtacga tcgctgactt caagtttggc aagaatattg gacacgtggg
    51781 tcttgaccgt cttgagagag ataaagaggt catctgcgat gcgctgattt tcgtagccct
    51841 tggcgatgag ttggagaaca tctcgctcac gcgcagtcaa ttcttcatga agttccatat
    51901 gattgcggtg gtattcaacc ttcttgctaa cctcttgctc aatggccagc tcgccagcag
    51961 ctaccttact gacggcatga agcaattcat ctgcactaga agtcttgagc atatagcctt
    52021 tggcaccagc atctaagact ggcatgattt tttcattgtc caaataagag gtcacaatca
    52081 aaatcttggc ttcaggccat tctttaagga ttgctaaggt cgcgtcaatc ccattcatct
    52141 caggcatgac aatatccatg acaatgacat ctggacgcag ttccaaggcc aagtcaatcc
    52201 cttgagaccc gttggacgcc tcacccacaa cttctacatc gtcttggagg tcaaagtagc
    52261 ttttcaagcc caaacggacc atttcatggt catctactag taaaattttc atctttactc
    52321 ctttatcatt ccttatctaa caggggaata cggatatcaa ctgccagccc ttgcttggga
    52381 gctgttaata actgaaccgt ccctgccata tcttcaaccc gctccttgat atttcgcagt
    52441 ccataactca agtcgtctaa gcttcctaac cggaaaccaa tcccattgtc caccaccttc
    52501 agttgcaatt caacatctgt ctgatagagg tagacatcta ggcaagatgc ctgggcatgg
    52561 cggagggtat tgctaatcaa ctcttgcagg atacggaaga tatgctcctc gattttctta
    52621 ggcaatttcg tcatattctg cttgagacta accctaagat cactcttgtc ctcaagctct
    52681 tttaagagaa tctgaatccc ttctatcaag ctcttctgct ccagttcaac tggtcgcaaa
    52741 tgcaagagca aaacccgcaa atccttctgg gcagtttcta aaatagctgt gacactctgc
    52801 aactgggtct gcatcttttc tctatccaat ttcaaagcct gctgactgat acccgataaa
    52861 ataatgtggg ccgcaaacaa ctcctgactg actgtatcgt gcaaatcccg agcaattcgc
    52921 ttccgttcct tctcgataat ttcctcttcc tgatcaaggc tatgattttc agctttttga
    52981 agagcctctg tcaaaaggtt aagtttacct gataaggact tgaaactggc atccaaatct
    53041 ggatctacaa cctgaactac ttcttgccct gccaataaac gcttgagatt agcctgcatt
    53101 tttcttagag aaagctcttc gatccctcgc caaaacaggg ctaagagaca ggtcatggac
    53161 atgctgaaaa ccaacaataa aaagacaaat ttttctgttt tttcgacatc gtacaaaaag
    53221 atagaccagt caaaatcaag tatttccagc aagctgtggg agaaaaaaaa gacaaatagg
    53281 aaggaggtga gagcaataat gacataggct tgttttttca tcctctaacc acctccacat
    53341 caccaatcat agtggtcaag aaaatcttga cactcttgtt actcttgaga tagtcttttg
    53401 tttcttgatg atagtgttca ttgcggaggg ctcgcttggg ctggttgaaa aaagtcaaat
    53461 ccccatagag acagttaacg ctgagactga cttccacatc tacaggtacg atgattttgg
    53521 tcgttcctac catctttctg aggataatga cattgtcatg attggttaag atgactctct
    53581 ccagatgaat agtgtccttg cccatgaagc gaaagagatt gatatcatca aattggcaag
    53641 tctggtagct tgaaaaatga tgaagatttc caaaccaacg atttttctcc ttcttaaccg
    53701 tcacaacctc ttcaaaaacc aaattggtct gctctttttc ctggttcatc atcgggtaaa
    53761 gaagaaagag actatagata accgcaacaa aaatagctag aatcacaaaa ggattgagca
    53821 taacgatgaa aaagaagaga atggttgccg ctactaaaag aagattattc ccctctttac
    53881 cagtatagta gcgaatcaaa agcaaaaaga ggaatagtat cagcagaaaa cgcgaaaaat
    53941 gctctgatac catcaaaatc agagctcctg tcagaagaca ggcttcgata aataaaaaga
    54001 ttttaaattt tctcataggt tcatcctctc ccttctattt tatcacaatt caaaaaagtc
    54061 acctcagtct gaggatggaa aaaaaggcgc tggttacgcc tttttcatct gatcctttgc
    54121 ttcttttaat tttccataaa gaagatagtc tactttttgt agatctgcta tggtggcaca
    54181 gttaagggaa cacataatca agcgtagatc tgctttccag ccttggacaa tgccaatcac
    54241 ttcttcaact gtgtaggttt caaccaattc cagaacggtt cgtgacaatc ccacagcctt
    54301 agcaccaaaa accaagcact taatcatatc cagcggattc cgaacccctc cactaaccaa
    54361 gagttcgacc ttatctttcc attcttgggc attgagaagg gcctgcatgg tagactgacc
    54421 ccattgattg aggtaatcac gctggccact acgacggttt tcgatatagg caaagctggt
    54481 gccaccacga cccgataggt ccactgtacg aacaccgaat tcataggctc tttcgattgt
    54541 cttggcatcc attccaaagc ccacttcctt gaggacaata ggaacgggaa tttgcttgct
    54601 ataatctgct agatgcgatt gccagcttct aaacttcctt tctccctcgg gcatgagtaa
    54661 ttcctgcatg acattgacat gcacttgcaa tagaacagga ttcatctctt ctacagtctg
    54721 aagtcctaac tcgacaggtt tgtccaatcc aatattggtt ccaaggagga gattgggatg
    54781 actagacttg acagaaaaag aatcatccgt tggatttttg agggctgcgc tataagaacc
    54841 cgttacaaat aaaataccac aggattccgc cacctgagcc agcttttgat tgatttctct
    54901 tcccttatta cttccaccag tcatggcatt gatataaaaa ggaaagtccc actttcgacc
    54961 agcaaactct gtcgaaagat cgatttcatc cagattgtaa agaggcaagg aagaatgaat
    55021 cagctccacc tcatcaaagc tattatagga acttttctgc tcaagggcat agaggatatg
    55081 ctcgtcctta cgatttgtcg tcatgtccta tcctttcttg atataagagc tcaatcccca
    55141 gatcggccca acgatttttt aaggttttgg ttgattgcgc atcaaaactc agggcgatgc
    55201 cacagtcacc accaccagca ccactactct tggcaacggc ctgcaaatct tgactggctt
    55261 ctttcaactg tctaagcaaa ggcgtgtaaa tatctgtact caagccttct aaaagcttgc
    55321 tggctacttc tacttgctcg ataatctttt ctgatttccc ctgttccaag gcttcgacca
    55381 aagaaaccac cgtttctttt gaggaactta aaaaattttg attgatattt tgcttgattt
    55441 gctggaccat gtgactcgat acagccactt ccttggtcca tcccactaag aaatcacatt
    55501 ctaaagttgg tttcacttgt gaaattgaaa agccccaatc acgctccaga actgtcgcca
    55561 agttttcttc ttctaaccaa gcagccacct tctggcgatc aaatgactgg tagagaacca
    55621 aatcctctgc cacaatacag gcaaggtcgc ccatggaacc attgtctcct cgcttgagca
    55681 agacagcgct agtcagcttg aacaagagct cctgatcaac agaaacatca tacagagcca
    55741 gtaaagcctt gacaaccaag acaacgacgc tgccactaga acctagacca aactttttcc
    55801 cttctcgttc cattttgcca cagatttcta gggaaaaaga tcttaaattc tgaccgcgaa
    55861 cagcgaggaa gtctcccatc aaagcaatcg tttcttgaat caagctgtag tcaggattgg
    55921 gcgttaagtc cactgcgaaa tcaaacatat ctgaatagat acggtagctg tcagaaaaag
    55981 caatctcagc cctcatatag atgggaatat cctttatcaa agctaactgc cctggctcta
    56041 aaatagcata ttcacctgcc caatagagtt ttccgcaagt tttaacagca atcatcttga
    56101 ctcaaatcct ttgtttttga cacaatcaag cgataacgct gaccgaaaat ttctgacaaa
    56161 tgctccaagt ctttctcctg acaaaagacc ttaacattgg gaccagcatc catggtaaag
    56221 tagcaggcct ctcctttctc acgaagctgg cgaacaaagt ccatagcctc ataagaggca
    56281 tccgtcagat aagaaaaggc tggactagca gtctttgtcg tagcatgcat agccagggca
    56341 tttttctccg ttaattctcc aatcttggca aaatcatttt ccttgagata aatcagcata
    56401 tcctgatagt ccttctcaga ctgacgaacc cagtcgtcaa aagtcgtcga ggtttccaca
    56461 caaagtttca tcccgtcacg gctagagatt ggttttttct tgtcctctag caccaacata
    56521 atcatagcta gtttcaagtc tgtctctaca gagtaaattt ctccactatc cttatcccag
    56581 gctcctagcg gtccataaaa actccgagaa gaagagcctg aggcaaactt ggcttcctgc
    56641 gctaactgac ttctatccaa tccaagcttg aaataagcat tacaagcctt gaccagggcg
    56701 gacaaaccac tagaacttga ggacaggccc gctgcagtag gcatattgtt ttgagtatcg
    56761 atacggacaa agccctcacc agctggacga taacggtcaa taatcttact catcttggca
    56821 tgctcgacct cattttgtag ctgaccattg atgtaaaatt cgtcagctat tacattggct
    56881 ggtaaaggcg acaaggtcgt ctctgtatac atattttcca aagttagaga aatactgcta
    56941 gtagcaggca ccatctcttt ttcttttttc tttccccaat atttgataat agcaatattt
    57001 gcgtaggaac gtactgtcac aggctctcta tccatgtctg aacagctcct ttctcttcta
    57061 atctttctgc tagttcttgt gcgtgtgtca aattggttac caaggctatg atacaacctc
    57121 ctagcccacc accgctcatc ttggcaccca gagcaccatg gctaagagtc gtttcaacca
    57181 aaaagtctgc ctcagggcta ctgactccaa tttcttttaa atgtaaatgc gcttgactga
    57241 ggatttgtcc cagtccttca gcatcttttt gtgaaatcgc aacttctgct tgctgggtta
    57301 attctcccaa ggcatgcaaa aacggtaggg catccttgcc cttattttga accacttgga
    57361 tggcttcacg agtatgacca taaacacccg tatcggcaat caccaaatag gcggataaat
    57421 ccatctcaag ttctgtaaat cctacgttct tgataaagcg aataggttgg tcactgagac
    57481 aggtcttagc atccaaacca ctaggattca tatgggcaat catctcagct cgattgacca
    57541 agatttctag tacatcatga ggcagatcag cctgatagta gtcaaatacc gcacgaatgg
    57601 ccgctatgct gatagccgct gacgaaccca tcccccgttt ctcagggata gccgagtcaa
    57661 tctcacaacg aatgcaggct tctgtgatat ccaaatactc cagtgaggca taaaccgcca
    57721 tggacaaggt atcctcctca taaaggcgcc aaggactctc tgcaggaact accttacagg
    57781 tcacctccac ctccaaaaga ggcagggaaa tggcaggata accgtaaacg accgcatgtt
    57841 cccctattaa aattatctta ctatgtgcct gaccgacacc aacttttttt gtcatttttt
    57901 ccttttacta gacgaaaaaa cgtcttattt ttcatacaag tattaattct ttcctatcta
    57961 ttttattata ttttcacaaa aaaagcgatt gtttccattc acaatcgctt ctttcattat
    58021 tgaacccatt cgccattata gttgacagaa tagccatcta cggtcgtatt cactgccaag
    58081 gcacctgagc tataagcgta gtaccatctg ccattgacct ggaaccaacc tgtcgtcata
    58141 gaacgacgaa agaaactcca taccgttaag taaagaggaa agtcgtgagg gatcatgcgc
    58201 cattgacaac ctgttttagt gacgtacaaa gtctcattaa caagtactcg tttcggccat
    58261 ttataggtgc ggtgtttgga gaaatagggt tcaatcttag cccattcttg atcgtttaaa
    58321 tcagtatcat atgctttgcg tgtcataact ctagtttaac attttttgtg aatacaagtt
    58381 ctaaataatc gaccacgaaa atttcttaag tggaaaacgc cttatgaagt atgctacggg
    58441 aaacttatgc acttaatttg acaattcaag atgtaaaaat atatactata gtagattgaa
    58501 actagaatag tacacctcta cttctaaaac atttttagaa atcgatttga ctgtcctgat
    58561 cgatttgtcc tgttattatt ttattttact ataatatttg acaagttatc ctaaaagtat
    58621 tattatgttg ttgtgttata gattgattga atctaactaa aggatcctat tcaattacta
    58681 gaactatcac atactcaagg tcagctcaca gatgagcaac tattttggtt acaatgtcta
    58741 ctaaatttaa gtcaaacaaa taatttagtc aaaattaaaa aaatagagga acataaatat
    58801 gattacaaaa cagaatgtaa tagtgttcta cgatttttac tagataaaac tgtaaattct
    58861 gaaggaagga tcacttcttc aacagaattt ggaaatttcg taagtaattt atcattccaa
    58921 cacggaatag ctggactact gtttcctcta aataaattgt accccccaga actggattct
    58981 aaaatactct ctatcatcaa gaaggcagtg acaattagaa cgacacacat atgaatatca
    59041 atactcactg ctatttggtg atgcaggcta tctatggtta ctcctacatt tattttctat
    59101 cagtaaaaat caatactatc tacaattagc aaacgtcacc gctaagaaat taatagagaa
    59161 ttatgatact ctagaagaaa tagactttgc attgggaaaa tctggtgtcc tattatcatt
    59221 aataaaatac tatcaattta ccaatgacaa tactcttaaa actttcatcc acaatagtat
    59281 atggggaaat ttatcattat ttcctacaaa gagatacagc caaagaaagc attttagact
    59341 atagctttgc tcatggatat tgtgaaattg catatgcttt atttgcctat tctaaagtct
    59401 tagaaccttc tatgttctat aatgatctcc atacattcca tgctgaatta aaaaaattat
    59461 tagaaaaagt tacttctaat actgaaaatt taggaaattt acaactttct tggtgcgaag
    59521 gaatttccgg aataatctta tatctttgta tgtacgattg tgacggaaac aaagatatta
    59581 ttagtaaata tcaagaattt gtttttaacc atcatctaaa aatgatgaca ggatattgcc
    59641 acggaataac tagcttacta caaaccactg tctacaatca aaacaaatta ctgatgaaaa
    59701 aaatccaaca ggtaatttta gcatgttctg aacgagatga tcacggttta ctgatgtttc
    59761 aaggagatag tggtaaagca gatttgtttg acttcggaat aggaagcagg gggtatattg
    59821 gtgtctatta aataataaat tcccattcga tgtgcaaaca taaggagaaa tgtatgaaat
    59881 tattttggac aaacaacata tatagacagt tgctgctaaa cagctgtttt tcatcattcg
    59941 gcgacagtat tttctacctc gccattatca attatgtggc tcagtacaat ttcgctccgc
    60001 tagcgatttt actgatttcc atttcagaga tggttcccct actatcgcaa ctctttctcg
    60061 ggattctagg agattttcaa gaaaatagag tcaaacacgc actctgtatt gccaaaatca
    60121 aaatcctgct ctacgctatt ttgacagtat ttctcgtctt gtcgcccttt tcattagttt
    60181 cagtcattat gattgtcatc atcaacctca tctctgacac cttgagctac ctgtctgcct
    60241 acatgatgaa cgccctctac atcagtgtaa ttaaggatga cctgcatgat gccatggggt
    60301 tcaggcagtc tctgatgagg gttgtccaca ttgtcgccaa tctggctggc gcattcctta
    60361 tcaatgttat aagtattcaa actatttccc ttatcaacac tctgactttt gtcattgcct
    60421 ttttgggcct gtatgttatt cgacatacct tgtatgaggt tgaaaaaagg attgaaatgt
    60481 cacatacagc actgagtttt aagaaatatt ttcaacatct taaacagtcg ctggctgtgc
    60541 tcctgaggtt aaaagatacc gtcatactac tgtttctgac gaccagtatg attgccatct
    60601 tggatgtgtc ccctcggctg attgccctcc gcttcatcca acagacacta gcacaactga
    60661 gcattgggca actcttcgcc ctgctctcca tcatcatgtc ttgtggagct atccttggca
    60721 atatgaccag cagtaatcta tttaaaaata tccgtttcac gcacctcttg gttttctgtg
    60781 agatttccct attggctcta ataactagta tcctttgtca agcctatatc gtaattttcg
    60841 tgaccagttt catcagttct acgattatcg gcattctcag ccctcgccta caagcagctg
    60901 tctttgccca tatccccagt gacaagatgg ggacggtggg ctctgctctg agcacagtag
    60961 acattctcgc cccgtccctg ctctccctat tagccctatc catagcatcg ggcgtttcgg
    61021 tgcagttagc attgatattt ttgtatctta ttttgattgc tcttatcttt tgtcaatggt
    61081 tagtcaagtt caacactcat aactaacgaa aaagcatgtg tagatttcac atgcttttaa
    61141 tctccccaat cgtcaggtca agtacaacaa agtcacttct ttgattaagc gagtgttcta
    61201 atataattat aagcgccctg tcattaccga acccattcgc cattatagtt gacagaatag
    61261 ccatctacgg tcgtattcac tgccaaagca cctgagctat aagcatagta ccagttgcca
    61321 ttgacctgga accaacctgt cttcatgtct ccattacctg catttaggta gtaccaagtt
    61381 gaaccatctt gataccaacc agttgccata gctcctgatg aacggagata gtaccatttg
    61441 ttcccaaggt tttgccaacc tgttttcata tcgccatttg gctggtctaa ataataccaa
    61501 gtggtacctt cctgatacca gccagtggcc attgctcctg aggaacggag gtagtaccat
    61561 ggagcaggtt tgcttctatc aatgtcaata gtaacatgaa aatcttgagt ccaaccctta
    61621 gcaacttcac caattggtag tggattgtaa gaatcatcac caaaatttcc tagcttattt
    61681 aaataatacc aattgccgtc ttcataaatc cagcctgtct ttacagcata attattatca
    61741 aaataataag ttctcttttc agcagataga ggatattgtt caccgtatac ttttcctgta
    61801 ttttcagacg tttttgcctc tagtacttgt ttatctgttt gttctagcaa agcaccatct
    61861 tgtccaaaat agtaccactt ctcctgaagg ccaatttcga agactggacg attatcaaat
    61921 aaatcatcac gataacctgt tccaggaatt tctaagtatt gccaaccgac aaccatctct
    61981 ccaatatcac caaaatagta agttttaccg tctattttat gccaatagat tgctttatga
    62041 tcatctttta cataatattt tctattatcc ttatcaacaa atcggccacc tgtggtattc
    62101 gcaaataccg tatttgtagc tagcaaacca aagaaaaaga ctgctagtag aacttgcatc
    62161 atttttttca aaagtttcat ttatatatcc tcctaaaacg attgtagcaa agacacgact
    62221 gcatgtcaat atataaaaac tcctcaaaaa agcagttaca caactgcaac tgcttttcta
    62281 ttcttgcatg gtgtaaccaa caccacgcac ggttttaatg tagctttttt gtcctttaac
    62341 atcaagcttg ctccgtagat agcggatata gacatctacg atatttgtct cggtcgcact
    62401 ttcatacttc caaacacttt ccaacaattg ctcacgagtc aatactttct tgcttcccat
    62461 aagtgtcgcc aaaaggtcat actcacggcg ggtcagagca atcatctctt caccacgata
    62521 aaccgtgtga tgttcaacat ctatcctaag attgcggtag gtccttggaa ctttcatcag
    62581 actgcagtgt tgatcaatga agtcccgacc tcggaagatc gccgaaatac gcgctaccag
    62641 attttcgata aagactggct tatagatgta tgaaactgca aaacgctgaa caacttccag
    62701 ctcttcttgc aagtcttccc aatgatctaa aatcatgatg actgaggcag gtttagttcg
    62761 actcaatttt tctgcaaaat cctgagccat catatctccc agattaacgt tcaataaaat
    62821 caaatcatag tctgtctgaa gagccatgga aagggctttt tgcccctcct ctaccagatc
    62881 aacccgatac tgctctttct ggagttccaa acttaaaaaa tgagctagat ttcgttcttt
    62941 ctcaagtaat aaaatccgtt tccccatggc tgacctactt atttttcgtc ataccaagag
    63001 tagtggaagg ttccttcttt gtctttacgt tggtaagtgt gagcaccaaa gtagtcacgt
    63061 tgtgcttgga tcaagttagc cggaaggtca gctgaacggt agctatcaaa gtaagtaata
    63121 gctgctgaga aagttggcac tggcacacca gcttgaaccg caagagctac gatatcacgc
    63181 actgcttgtt gatacttagc agtaacatcc aagaagtact cgtccaaaag aaggttggca
    63241 agatctgcat cgcggttgta agcatctgta atcttttgca agaaacgaga acggatgata
    63301 cagccatcac gccagataga tgcgatatct gcaaatggca agttccagtt gttttcttta
    63361 gaggctacac gcaattgagc aaatccttgt gcgtatgaaa tgatttttga gaagtaaagg
    63421 gcttgacgga ttttttcaat caattcagcc ttgtctcctt caaagttgaa ggcagctggt
    63481 tttggaagca ccttgctagc atgtacacgt tcttctttgt aagttgaaat gtagcgtgca
    63541 aacactgact cagtaatcag tgacaatggt acaccaaggt caagagatga ttggctcgtc
    63601 catttaccag ttcccttgtt acctgcagca tcaaggatgt agtctacgat tggtccatct
    63661 tggtcttcat cgtctttacg gctcaagata tcagctgtga tttcgatcaa gtagctatcc
    63721 aattcaccct tgttccactc agtaaagatt tcagccatat cctctgcaga aaggcctagc
    63781 aagtgttgca tcaagtcata gctttctgcg atcaattgca tatcaccgta ctcgataccg
    63841 ttgtgaacca ttttcacata gtgaccagct ccatcaggac cgatataagt cacacatggt
    63901 ttgccatctt ctggtgcttt agctgagatt tcttcaagaa catccgaaac caattcgtag
    63961 gcctcttttt gtccaccagg catgatagaa ggaccttcaa gggcaccttt ttcaccacca
    64021 gaaactccag taccgataaa gttgatacct gagtttgcca attcttcatt acgacggatg
    64081 gtatctttgt agaaagtgtt tcctccgtca atcaagatat cacctttgtc aaggtgtgga
    64141 agaagggctt ggatagtagc atctgtacca ggtccagctt gaaccatcag catgatacga
    64201 cgaggttttt cgattgagtt tacaaaactt tcaacgtcat agcttggtac aaaattcttt
    64261 tcaggatggc aagcaatcac atcttccgtt ttttctttac tacggttgta gatagcaact
    64321 gtgtaaccac gtgattcaat attaagggca aggttacgac ccattacggc catacctacg
    64381 acaccaaagt tagcttttgt catttgacac tcctcttgtt tcatttgttt tattttatca
    64441 tttttacttt tgaaaagaaa gaattttgta acgactgctt agtagtccaa gtcatccgca
    64501 tgaccagcgc catttccgac aaagtagcct gtcttacagt taagggtaaa gagataggtt
    64561 ccatctggct tatagaggtt gtaataacca ttgccgttaa cgatattgac acgttcaagg
    64621 atatattggt ctccagtgat atagccacgt gaacgtgaag ttgctagaat ttgttccaaa
    64681 acaccatccg caaaatccca ggcagagtta ttactatcat caatagcaga ctgattatag
    64741 gcaacacgac tggcacttct ttgaacagca acccctgcac tcgagagacc catattgact
    64801 tcactgcgac tacttctagt ctcatttgaa ctacttggtt ttggctcact agtcgtattt
    64861 gaacttgctt gacttgaact tgagctgcta gtttgacttg aacttgagct agaagtactt
    64921 gtttgctggc tcttaccaag actgatagcc ttatctagca ctttatcaag ctccgtattt
    64981 ccagttttaa tatccgtaaa tttagcatcc gatttggctt tggcattggt atccaacaca
    65041 ccatccacaa tagctggttt ttcaaattgt gcattgacat cttgaatggc cttgatttgc
    65101 gttactagac tatcatattt agatttggca agcgtatgtt cacgactacc ttccagctta
    65161 tcaagtaaag tcttgagttg actcagttta tcaaactggc tatttttcaa agccgtttta
    65221 ttgctatttg tgtaaaaggc gtcataaagt gtattaaaat catccacatc cgattgattg
    65281 gctgtagttg attgagaagt ttcaatttcc ttggtcgaac gagccacttg acgatagaca
    65341 taataagcac tgacacaaat aattactgat acaagcgcca aaacggtcaa aataaagcct
    65401 tttttacttt tcttttctga gtcctcttga tccagacgag aaaggttttg ctcctcttcc
    65461 acttcttcag tcatttctgt tggattttca tcatctagca atagaggatc caagccttgc
    65521 tcctcatcgt ccagaggcaa gggtagtaag atgtcttcag aagatggaac ttcctccgaa
    65581 gaagcttctg acttctctac agcctcacgc atctcttgaa ttaaatcatc cagactctga
    65641 gtttcaacga actcctcttt tttgtattga cgagtcgcaa acttatccgc ctcaatttca
    65701 tctctgtgtt gcttaacata cttgtccaaa atggaatcct caggcaagac tcctgcttcc
    65761 acttcttcat ttttacgaat agcttgacca actgttagct cttttgcttc atcaaaatca
    65821 aattgcggtt cttgaccttc ttttttatga cgatttcgtc tttttttact catgagtatc
    65881 cctttctatt ttacctcttg ccgtttgaca cgctgaccaa aatattgata tagatccact
    65941 ttcaaggttc cgttgtataa cttacgcttc ttatctgctt ggctaccata cttgctttca
    66001 aaagcttcat cactagtcag gataaatttg ctccaagttt tcagcggtgc aaatacttgc
    66061 cccatctcag catagagctt ggtcactcct gcatcatctg acaaacgttc accataaggc
    66121 ggattggaaa tgattactcc attgatttta tcggaacgta aatcctgcac gcgcatctgc
    66181 ttaaaagtaa tatctcctgc aacaccagct gcctgagcat tggccttagc aatttccacc
    66241 atgcgagcat caatatcaca gcccatgata tccaactcaa gcttacgttc tactttttta
    66301 gccgcttctg tgcgcacttc ttgaatcaag cgatcgctga tccagttcca ttcctcaaat
    66361 gcaaaagagc gacgaagacc tggcgccatc tttctagcaa tcataactgc ctcaatacag
    66421 aaagtccccg aaccacaggt cggatcaatc aaaggcttgt ctggatacca gttagaaagt
    66481 tgtaaaatgg ctgctgccat attttccttg ataggagcgc cacctttttc ggtacgataa
    66541 ccacgtttaa agaggctaga cccggtcgta tcaatcatga cagttgccac atctttgaga
    66601 atagagacct caatcttaaa ctctgggcca ttctccatca gaggaacccc ttctgggcga
    66661 gcatagtgtt tctgcaattt cttgacaaca gctttcttag aaatagcctg aacactgggc
    66721 tcattgtgaa gtttggactt aacacattta gcttttgaaa tcggtaaccg agctccaagt
    66781 ggtaaataat tttcccaatc taaagcgaaa actccctgaa atagctcttc aaaagtctta
    66841 gctgggaacg ttcctacgat aattttgata cgatctgctg cccgaagcca aaggttggtt
    66901 tcgataatag ctctcacgtc tccttgaaaa cgaacacgtc cattttcaac ctgacaatcg
    66961 tagcccaact ctcgcacttc acgaccaacg acagcctcaa gccctgctgc cacagttgca
    67021 attaaattaa attctttttt catgttacag tcttgcaaga cctttctata tgtccacttt
    67081 aaaaaatgag gttgagaaaa tttctcagcc ccaacctata tgcaattttc tataagccat
    67141 gttttgttcc agaagtgact aggaccactt ccttcgataa tcatctgtct accactaaca
    67201 gctctagctg atagcagtca gaatactacg ttcgtttccg catactccat gccccgacca
    67261 aaatttgggt tgctagcttg aggggtttac cgcgttccac tctctctgtt tccagaaaga
    67321 ctccgtcact gtggcacttt caagcctact ctggcctatc caaggactta gccatttcaa
    67381 ctgccgtaac gatttctcgt ccctaggctt atggtttcgc ctagcacaaa cactacaggc
    67441 atcacagcct gtgctagcat ggactttcct catgagaagc aattctcctc acgcgattat
    67501 ccaaaaattg cacatctcaa ataactactt aaaaatctga gttatctaaa atttgtttac
    67561 caaaaacttc tttttccaat ctattcaggc gtttcaaaat atcaaaattc gtcatagaac
    67621 ttgtaattgc cgcttcaagg ggttctgctt gaactggtga aggtttcggt ttacgagtta
    67681 attcttcctt caaatccgca atttcctgac gaagtgactt gaccaaggca gcataggttt
    67741 catagtcctt gatgacatcg tctaaaaact cgtcaacttc tactttatta tagccacgga
    67801 cttcacgtcc aaactcttgt tcaaaaatat ctttcgctga aaaaataata cttgccatgt
    67861 ctctctccat tctcgcttgc tagtattatt atataaaaaa aggcaaacaa aaatcaaggt
    67921 caaagcttca attttcggaa aaattttcag caagttcatt taattgatca aatgttaatc
    67981 tctttataaa atagtcctct tgatttttca tcttttggta aaaataagct agttttgttt
    68041 cattttcttc atcataaaaa agataggaac tagtcgtgtt ttccagcaaa aactgctggt
    68101 aatctcttaa ctgccccttg tgttcatagc gaggataagc atatttgaca aagtctacct
    68161 gcttaaagcg actcagtttc atctgattgc cttcattcca attttcccca tgggtttcaa
    68221 aagcaaaaat ggtggccaac tggaaaccgt attcggtttt catctcctga gcaacctcta
    68281 aaacccaata ttcaaaaccc aaactccctg taaacacaag ccaagacacc ccatctgctg
    68341 ccatagcctc taaatcttta cgtatcgctt ttttaatcaa tttaagacga ggatccttat
    68401 cagaaaataa acccaaatca aaagcagaat agcctaaaac caaagctgta gccattttta
    68461 accctttctg tgcaaattat ggtataataa agtgatgtta ttgtaccaat aaggagaatt
    68521 atgatcaact atccacataa agtttcatca caaaaaagac aaacatctct ttctcaaccc
    68581 aaaaatttcg caaatcgagg aatgtctttt gaaaagatga tcaatgctac caacgactac
    68641 tatttgtctc agggcttggc tgttatacat aagaaaccaa ctcctattca aatcgtacaa
    68701 gtggactatc cacaacgaag tcgtgccaag attgttgaag cctattttcg acaagcttca
    68761 acgacggact attctggcgt ttataatgga tattacatcg actttgaagt caaggaaaca
    68821 aaacaaaaac gtgcgattcc gatgaaaaat tttcatccac atcagattca gcatatggaa
    68881 caagtccttg cccaacaagg aatctgcttt gtccttcttc acttttcttc tcagcaagaa
    68941 acctacttat tgccggcatt cgatttgatt cgcttctatc atcaagataa gggacaaaaa
    69001 tcaatgccac ttgaatatat tcgagaatat ggatatgaaa tcaaggctgg tgccttccct
    69061 caaattcctt atctcaatgt tatcaaagaa catttattag gtggtaaaac aagatgaaca
    69121 aaccaacgat tctgcgccta atcaagtatc tgagcattag cttcttaagc ttggttatcg
    69181 cagccattgt cttaggcgga ggagtttttt tctactacgt tagcaaggct cctagcctat
    69241 ccgagagtaa actagttgca acaacttcta gtaaaatcta cgacaataaa aatcaactca
    69301 ttgctgactt gggttctgaa cgccgcgtca atgcccaagc taatgatatt cccacagatt
    69361 tggttaaagc aatcgtttct atcgaagacc atcgcttctt cgaccacagg gggattgata
    69421 ccatccgtat cctgggagct ttcttgcgca atctgcaaag caattccctc caaggtggat
    69481 caactctcac tcaacagttg attaagttga cttacttttc aacttcgact tccgaccaga
    69541 ctatttctcg taaggctcag gaagcttggt tagcgattca gttagaacaa aaagcaacca
    69601 agcaagaaat cttgacctac tatataaata aggtctacat gtctaatggg aactatggaa
    69661 tgcagacagc agctcaaaac tactatggta aagacctcaa taatttaagt ttacctcagt
    69721 tagccttgct ggctggaatg cctcaggcac caaaccaata tgacccctat tcacatccag
    69781 aagcagccca agaccgccga aacttggtct tatctgaaat gaaaaatcaa ggctacatct
    69841 ctgctgaaca gtatgagaaa gcagtcaata caccaattac tgatggacta caaagtctca
    69901 aatcagcaag taattaccct gcttacatgg ataattacct caaggaagtc atcaatcaag
    69961 ttgaagaaga aacaggctat aacctgctca caactgggat ggatgtctac acaaatgtag
    70021 accaagaagc tcaaaaacat ctgtgggata tttacaatac agacgaatac gttgcctatc
    70081 cagacgatga attgcaagtc gcttctacca ttgttgatgt ttctaacggt aaagtcattg
    70141 cccagctagg agcacgccat cagtcaagta atgtttcctt cggaattaac caagcagtag
    70201 aaacaaaccg cgactgggga tcaactatga aaccgatcac agactatgct cctgccttgg
    70261 agtacggtat ctacgattca actgctacta tcgttcacga tgagccctat aactaccctg
    70321 ggacaaatac ccctgtttat aactgggata ggggctactt tggcaacatc accttgcaat
    70381 acgccctgca acaatcgcga aacgtcccag ccgtggaaac tctaaacaag gtcggactca
    70441 accgcgccaa gactttccta aatggtctcg gaatcgacta cccaagtatt cactactcaa
    70501 atgccatttc aagtaacaca accgaatcag acaaaaaata tggagcaagt agtgaaaaga
    70561 tggctgctgc ttacgctgcc tttgcaaatg gtggaactta ctataaacca atgtatatcc
    70621 ataaagtcgt ctttagtgat gggagtgaaa aagagttctc taatgtcgga actcgtgcca
    70681 tgaaggaaac gacagcctat atgatgaccg acatgatgaa aacagtcttg acttatggaa
    70741 ctggacgaaa tgcctatctt gcttggctcc ctcaggctgg taaaacagga acctctaact
    70801 atacagacga ggaaattgaa aaccacatca agacctctca atttgtagca cctgatgaac
    70861 tatttgctgg ctatacgcgt aaatattcaa tggctgtatg gacaggctat tctaaccgtc
    70921 tgacaccact tgtaggcaat ggccttacgg tcgctgccaa agtttaccgc tctatgatga
    70981 cctacctgtc tgaaggaagc aatccagagg attggaatat accagagggg ctctacagaa
    71041 atggagaatt cgtatttaaa aatggtgctc gttctacgtg gagctcacct gctccacaac
    71101 aacccccatc aactgaaagt tcaagctcat catcagatag ttcaacttca cagtctagct
    71161 caaccactcc aagcacaaat aatagtacga ctaccaatcc taacaataat acgcaacaat
    71221 caaatacaac ccctgatcaa caaaatcaga atcctcaacc agcacaacca taacatttat
    71281 cacccagatt tttctgggtg attttgtcat agcactattg tatttatgtg cttaacaaaa
    71341 gcctgagaag atgtcttctc aggctttttc tgtactataa acctcattgg aaaagataga
    71401 gactgcttcc gtaatcttgt taagaggttt tactaaatac tagtctttct tcgtttttac
    71461 tacaaagaga gcagataggg ctagactaac acttgctagg aagagggctg tgtcagattg
    71521 actctcacct gttgctggca agatttgttc aggtgtttct ggtctagcta tttcttgctt
    71581 ataatctggc gtcttacctt gatcggaaac taaagagcta agtttaaact caggtttctc
    71641 tacagttgga gcatctggtt tcgtagcaga atcttttaat tggttgagat aatctgcaaa
    71701 gtattccacc attctttccg tcaagagatg gttatccgtc gcatatttca tgcttgcctg
    71761 aacgctagct acttcctctt gattgtcttt gtctgttaat ttctgagctt tagccaaagc
    71821 tgcttcatag cctgacaagt caagaggtgt ttctgctacc tgtggacgag taaagatgag
    71881 ttccgctgca gattggtatt tatcgccacc atctccgtaa gtcttagtac ctgtaaggac
    71941 aattttctta gccttaattg tcttaccaaa atcaatgtct tttggcttat tgttatctgg
    72001 ccaatcagtt gcagtaaagg tatgctcctt gccagactca tctgtcacaa caagtttcac
    72061 atcacgcaag ttaccatttg aacctgatcc acgtggaacg taacgaagtc cagtgatttc
    72121 agttggttct ttcaagacca tggttgcagg cttgcctaca tctccaccat tccaagatgt
    72181 atgccataaa ctagataagt ttccatcaaa ggcatttgca agaccttctt gagcctgagc
    72241 aggagctgta agacttgcaa agtcatctgc taccaaagcc gttttcttct gaaccaaagc
    72301 attcttcaag gcttcaatct tggcaatctc tgcacgcgct tcttccacac tgatatcatc
    72361 atcggcctga ctaaggttaa agaccgcctc tttcaaagca tccatagact ctttggtgta
    72421 gttagtcatg gcaaccgttg gcaagtagtt cttcagagca ttttctgtca acatcttacc
    72481 tgttagggta atttcttcga tttgaagatt atccatcatg aagtcgttat aaccacggaa
    72541 gttggcattt ccaccagaat caccacgagt attacttgca ttgccagttg agtagatacc
    72601 tacccaagta tcccctgttt ctgcacctgt cacaaggaag gttgccttct tggctttctt
    72661 agaatctgtc caagtatttg gcaattcatg catttccaag ttgcttgctt gagtgccacg
    72721 acgacctgac tggaattctc ccttaccgac tacaaaagca taggtattgt ctgaacctgc
    72781 ttcgtattca aaggttacac ggtaggtctt acctgcttca aaacggaagt tttgtgggat
    72841 ggtttggtaa accaagttac gacggctcac tagtccattt gtcttgagtg accaatttcc
    72901 ttcgataaca tcatcgactt tcttaccgtt ccaaccacgt tgtgtatatg gatcgtgttt
    72961 ttcagacaag tgagtgcggt tgtcttcgac accttcgaca ccacccacta caaatgggaa
    73021 gattccttga gctacatttt caaagtcttg cttgaaggtt ccttgacctg tatcgtgctt
    73081 gtctccatac atgcttgaat tgttttcaaa ggtacgaatt tcatcaaagt aagttgcttg
    73141 atcaccagct tcacgactca atgtcagagt aacatttgag acgtccgatc ctgttgtaaa
    73201 gaaggcgtac atgttttgga agtaacttgt atcgttaact gtagcattgt tacgacgtgt
    73261 attgtgggcg taggctttta catagttgag ggcgagagac ttattggtat aagtagtcac
    73321 ttctttttca ccagtattca cagtgatact tgccttggca ttactacggt tatcgacacc
    73381 gacataaacg gcatacttgg tatttggttt caagccagtt aatttctgag tgagactaac
    73441 tttttctttg tttccttgaa tacgaagcat atcgtttgcc ccttgagact tgacaatttc
    73501 tgccttagaa gcatcgcctg aaatggtcca atgtttcaag gtaccactgt taaatccttg
    73561 gtcatagatg tgcatgcctt cactccatga catttcagga ttggtttgtt ttgaacgata
    73621 gagaacgtat ggttgatttg ctagaagatc tagggtaatt ttaccatctt ttacagttag
    73681 ttcttgctct tctgtcttac cttggtcagt tagcttgtaa aggtaaacct tgctctttgc
    73741 ccaatcgctt ggaagggtcc aagttgttgc accggcctgc gtattgaagt agtacatctt
    73801 ttccttatca gtagaaagtt tcttaccatt tgcatcccag ttccaaggag tcaagtaagc
    73861 tgaaccatct tggatgacac gtccgttgag agttactgta cgttcgcgat attgtggact
    73921 attgacatca tttgacttac gagttacaac tactttatta ttgtcagcat ctaccaattc
    73981 cactcgcatt tctggagtcc atttataggt actaccgtta tcggtcatag tcaccggtgt
    74041 accattttcc catttactta cagtgaagtg ttggaagtac ttagtcatga cgtcatgggc
    74101 aaataagttg gttacatagc cattgtagtc acttcttccc tgccagcctt caaagtcttt
    74161 catgctgtag ccacctagca gtggatagtt ggctgcacca ccataacttc tgtagtcccc
    74221 aacccaagca tctttttggt ggttacggat aaagcgggtg atggcactgt tgataccttt
    74281 attggtgtag ccaccgtagg tcaagtcagc tgcccagtga tggaaggtag agtcgtactc
    74341 accaccatgg ccccactcga tcgcaaagcg ccagccttgt ttgttaattt ctttagcaag
    74401 aacgtgggta gcccaggcac cgttatcacc tgattgacca ttaccccaaa cgtccacata
    74461 gataaagtcg agaccgtcac caagtttttt cttcaaatct tcccaacgtg ccaaacgacc
    74521 atgagctagg tcataggcag catcaatgtt gataccttga tctagccagt tccaaccata
    74581 gctatagctt ccatctggat tcttacggag aattttttca ttgaagtatt tagactcagg
    74641 ataagtttct gaagcgttaa cgtggatacc tagatgagct ccatatttct tagccttctc
    74701 aattagggtc ttgaagtctt cgacaccacc gatacgctta ccaatatcag catagttcaa
    74761 gtgaccagag tcatggcctt cgctaccata tcctttaagg aaaacacctt gcccaagacc
    74821 atctgtgtgg agattgattt tcttgatacc atccaaggtc ataaggaatg gattttgtgc
    74881 ttgagaacca aagttcatcg cgatacggta agctgtgata tccttaactt tttcccaacc
    74941 ttgaggattg ttcataatgc tacgataagc aatggcacca tcttgccaat cgactttctt
    75001 gtctgcattg gcatcttcag tgataacaac cttagcactt ggaagttcct tcgtgtattc
    75061 tgggaaaaca atgcccttat aagctttttc ccattgccat tcagagctgt ggattcctac
    75121 atagttggca tttccgactg tttctttata agctgtcaaa cgagtccagt cattcgaacc
    75181 accaccatag ctattttgag agttactcca aacaccagca gcaagcttat ctgtagaaac
    75241 aaatccatac atgtaaccct tggctaggtc tttcattgga ttggttacat cgatatgatc
    75301 atctccgctg acatgcgtat tgtttgacat ggttgcccca tcaaacttag caccagtttg
    75361 atcactagaa acagagacta aagcattgcc gaggaaacta atagaagaaa gtagttttct
    75421 ttcgtcatca atcttttgac ctggagtgac ttgattgtgg ttgacaatct tggtcacatc
    75481 aaagtgcaat tgattgtcca caacttgcaa gcgtactgtc atttccgcat tgattaagtg
    75541 agcatcatcg cgaagcttca tcaagtactc tgctgttgtc tcattgattt tcttataagt
    75601 gacttcaggg gtgattcggt ggttattgat aaagacttgg ttgaactgtt gcacctgtcc
    75661 tggcaaagta tgtccattca agctgtattc cttgacacga gggaaggctt ggtcaatcac
    75721 tgctttgagg accttagact ggatcgtatc ataagtcacc ttgctatcgt caacaaccgg
    75781 acctgtttct ttctgggcag gagtatcatc cgcttttacg ccttcttgat tgtctgtttt
    75841 aacgctgaca actgtacggt cattgccata agttcctgcc ttgagaagga tcttcttctc
    75901 atttttaaga ttatcattga ccgccccagg cagtgtcact gtgtcaaaga gattgacatc
    75961 gttattgctg gcattgagtt gtccatctga cttgagagtg atagaaagac ggtttacaga
    76021 acccggttct ggtgcaacta cacggttgcc tttataccat gtgctattac ctggagtttt
    76081 gtattcccag aaccagccat ccttgtcata accgacaaaa acattattat tggtatcttt
    76141 aaatttcagg aagacaccaa agcgtgattt gcccttttca gaatcttctt tgaaggttaa
    76201 atcaacagtt gcatttccat tggcatcaac ggtcaagccc ttcttttcaa acagggctgg
    76261 tttgcctgcg ttatcatttt gagcagttga gaatagttgg ttgtagcgga cacctttttc
    76321 ttctcggata gtgactgttc cctgttgttc ttttttctct accgtttgcc attcaggagt
    76381 taccgtctta ggtgtttcag gtttagcagc tgcaggttta tcctcttttg gtttttcttc
    76441 agccggtttt tctttttcaa gtgctaatag ttcttcttct gtcttaggtc catctgtaac
    76501 ttctggagaa ccttggtctt ctcccacctt aggcgcttca aaatcacgcc catcattctc
    76561 gtttgctgtt gcaagagcag tagctaaatc agctggtaag ttcgccgtgg aaccagactg
    76621 cacgctatct gcaagaaccg gacttgtccc aaagaatgca gctccaatca taacagaagc
    76681 aacacctaat gaaaatttcc gaatactata tttacaacgt ttttcaaata atcctttatt
    76741 cataaacttc taaatccttt cattttttag caagcgttta catttccttt ttaaaaaata
    76801 ctccttcctc tgaaagtgca atgcttaacc ctgataaata aaaaataatt gtacttttaa
    76861 tataacaaat aatagctgag aaagcaatag gaaacaagta aaattaacaa aaattttctc
    76921 tattctgaca aaaagaggct ccaacttttg ggggtcagta catttagaat ctttctttac
    76981 aaatgtaaaa aaggattcag cattcaagag aaatactaaa tcctttctta tattttgcaa
    77041 cagttatttc acatgttttg cgagatcttc ttgagccttt ttattagact cttctttttc
    77101 tttcatccat ttttcctgag ctttttggta ttcatctaca gtgactgcct tgtcttgaag
    77161 ttccaagtat ttatacaaga ctggttcact tgtaccttta tttcctgaca atgcaaatgg
    77221 tattgtaaat ggtaccatct tagacaagat tgggcgccct gtacgagatg tagttggaat
    77281 aatcaaagca ctatctgtca accaagcttg ggctgcagcg tatttatcat agcgtttagc
    77341 aacatctgta gcctcatcac cagcctcagt gaccaatttt tcgtagtcat atagacctac
    77401 ttttttagca gctacattat cttcccctga gtcaaaccct aaatatgttt tagtactttc
    77461 tcctacagaa ggtttgataa tatcaaggta ggttgatgga tcggcaaagt ctggacccca
    77521 accgacatta tctgataaat cccagtcttc gccagcagca ttttcagcaa aatatgtaat
    77581 attgtttact tcgtcttttt gtagttgttg gatatcaata atgacattat cagctcctaa
    77641 agttgcttcc aaggattgtt tcatagattg gacgcgctga acttttgtag ttgctgtctg
    77701 gtcaactggc atatccaaat gaattgggaa agtcacacct tctgcttgta aggctgattt
    77761 agctttagca aattcagcct tggctttttc tggattgtaa agaccatcct gagaatctgc
    77821 aagattaaca tccttccatt catccccata agtgaccaat ttctctttga ccatatcgcc
    77881 aaagttttta ccatctgctt gaacaaatgt tggtggaaca aagatattac gtaagatttt
    77941 gcttgctcca gtttgtccat tcaactgaga ggcataggct gtacgatcaa aaccaaaggc
    78001 aatagcctga cggaaatcct tgtttaagag agccttttta gtcgatgcct tttgttcgtc
    78061 gctggtctta gatgtatatt tataggactg acggtcaata tttgtaccaa ctagatacgt
    78121 aatagagcct tgttgagtat agacaatatt gtccttcata ctcttctcaa gctctgcgaa
    78181 acttgcactt gttggataga gacgagctgc tgtaaggcta ccatctttaa agttttctgc
    78241 aggtttgctg gtatcttgac catcccagaa tgacaattta actttgtcaa catgcacatt
    78301 gtccttatcc cagtagttcg gatttttcgc aaattcaaca gaggattttg tcacaatgga
    78361 tttcaacaaa taaggaccgt tatacaagag actacttgga tccgtcgctt tggcaaaatc
    78421 atcccctttt gagttcaaaa actcttcatt aactggcgca agcacaccca tggttgtctt
    78481 agaattccag aagctttctg gtttgttcaa agtgtactga actgtctgat catccaaagc
    78541 cttaattcct acttgtgaga aatctttgat ttcccctttt acataggcat ccaacccttt
    78601 gattgattct tgaacaaggt aaagagcatc tgatttttta tcagcagcat attttagtcc
    78661 tgttacaaag tcttgagctt tgactgccgc gtattcttca ccttcagaag tataccattt
    78721 tgcatcctta cggatagtat aagtgtaagt caatccatcc ttggatacag accaatcctc
    78781 agccatagac ggcacaaagt tcccgtagcg atcattttct agcaaaccat caaccacgtt
    78841 actggtaata tttgctgtcg cagccttagc agttgtcaaa tagttgaggt tatcagggtc
    78901 tgtctcataa atgtatgaga atgtcttctc acctttagtg cttgaacctg atccagagca
    78961 tgcagctaaa gtagtcgccg ccaataatgt cacgcccgca agggcaagta gttttgaact
    79021 tttcatcctt ttctccttta aaactttctc tccattatag actcttttca gaaagttgtc
    79081 aacagaattt tcagaatttt tgaaaattat ttttcaaata acatctttgc aaaaaatatg
    79141 aatatcgtaa ccg
//
LOCUS       DAVBBO010000004        66960 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ST1
            SAMEA2066453-rid20184263.denovo.004, whole genome shotgun sequence.
ACCESSION   DAVBBO010000004 DAVBBO010000000
VERSION     DAVBBO010000004.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2066453
            Sequence Read Archive: ERR351777
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 66960)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 66960)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980402.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980402.1
            Genome Coverage       :: 176x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:17:33
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,141
            CDSs (total)                      :: 2,104
            Genes (coding)                    :: 1,953
            CDSs (with protein)               :: 1,953
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 16S)
            partial rRNAs                     :: 1 (23S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 151
            CDSs (without protein)            :: 151
            Pseudo Genes (ambiguous residues) :: 0 of 151
            Pseudo Genes (frameshifted)       :: 73 of 151
            Pseudo Genes (incomplete)         :: 76 of 151
            Pseudo Genes (internal stop)      :: 40 of 151
            Pseudo Genes (multiple problems)  :: 32 of 151
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..66960
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2066453-rid20184263.denovo.004"
                     /strain="ST1"
                     /db_xref="taxon:1313"
     gene            114..1031
                     /locus_tag="VQU30_000238"
                     /pseudo
     CDS             114..1031
                     /locus_tag="VQU30_000238"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001822901.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="sodium-dependent transporter"
     gene            complement(1071..2015)
                     /gene="manA"
                     /locus_tag="VQU30_000239"
     CDS             complement(1071..2015)
                     /gene="manA"
                     /locus_tag="VQU30_000239"
                     /EC_number="5.3.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398143.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannose-6-phosphate isomerase, class I"
                     /protein_id="HET2446428.1"
                     /translation="MSEPLFLQSVMQEKIWGGTKLRDEFGYDIPSEKVGEYWAISAHL
                     NGVSKVANGRYEGTDLATLYAEHRELFGNRPEPVFPLLTKILDANDWLSVQVHPDDAY
                     GLEHEGELGKTECWYIIAADEGSEIIYGHNAKSKEELRQQIEDKNWDALLTKVPVKAG
                     DFFYVPSGTMHAIGAGILILETQQSSDTTYRVYDFDRKDDKGNLRELHLEKSIDVLNI
                     GEPANSRPVTIKADDLRSTILVSNDFFAVYKWEITGKVNFEKTADYSLLSVLAGQGQL
                     TVDGKNYPIQKGRHFILPSDVESWTLEGQDLELIVSHP"
     gene            complement(2147..2428)
                     /locus_tag="VQU30_000240"
     CDS             complement(2147..2428)
                     /locus_tag="VQU30_000240"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000380698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="family 1 glycosylhydrolase"
                     /protein_id="HET2446429.1"
                     /translation="MDTPDENGYVADDYRITYLEAHIKAMRDAIYKDGVDLLGYTTWG
                     CIDSVSAGTGEMNKRYGFIYVDRDNVGNGTLKRSKKKSFYWYMSFIAMV"
     gene            2599..2819
                     /locus_tag="VQU30_000241"
                     /pseudo
     CDS             2599..2819
                     /locus_tag="VQU30_000241"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611577.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(2936..3283)
                     /locus_tag="VQU30_000242"
     CDS             complement(2936..3283)
                     /locus_tag="VQU30_000242"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003017645.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HET2446430.1"
                     /translation="MNLNQLDIIVSNVPQVCADLEHILDKKADYADDGFAQFTIGSHC
                     LMLSQNHLVPLENFQSGIIIHIEVEDVDQNYKRLNELGIKVLHGPTVTDWGTESLLVQ
                     GPAGLVLDFYRMK"
     gene            complement(3394..5169)
                     /gene="spxB"
                     /locus_tag="VQU30_000243"
     CDS             complement(3394..5169)
                     /gene="spxB"
                     /locus_tag="VQU30_000243"
                     /EC_number="1.2.3.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000191798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate oxidase"
                     /protein_id="HET2446431.1"
                     /translation="MTQGKITASAAMLNVLKTWGVDTIYGIPSGTLSSLMDALAEDKD
                     IRFLQVRHEETGALAAVMQAKFGGSIGVAVGSGGPGATHLINGVYDAAMDNTPFLAIL
                     GSRPVNELNMDAFQELNQNPMYNGIAVYNKRVAYAEQLPKVIDEACRAAISKKGPAVV
                     EIPVNFGFQEIDENSYYGSGSYERSFIAPALNEVEIDKAVEILNNAERPVIYAGFGGV
                     KAGEVITELSRKIKAPIITTGKNFEAFEWNYEGLTGSAYRVGWKPANEVVFEADTVLF
                     LGSNFPFAEVYEAFKNTEKFIQVDIDPYKLGKRHALDASILGDAGQAAKAILDKVNPV
                     ESTPWWRANVKNNQNWRDYMNKLEGKTEGELQLYQVYNAINKHADQDAIYSIDVGNTT
                     QTSTRHLHMTPKNMWRTSPLFATMGIALPGGIAAKKDNPDRQVWNIMGDGAFNMCYPD
                     VITNVQYDLPVINLVFSNAEYGFIKNKYEDTNKHLFGVDFTNADYAKIAEAQGAVGFT
                     VDRIEDIDAVVAEAVKLNKEGKTVVIDARITQHRPLPVEVLELDPKLHSEEAIKAFKE
                     KYEAEELVPFRLFLEEEGLQSRAIK"
     gene            complement(5376..7619)
                     /locus_tag="VQU30_000244"
     CDS             complement(5376..7619)
                     /locus_tag="VQU30_000244"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000136280.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heavy metal translocating P-type ATPase"
                     /protein_id="HET2446432.1"
                     /translation="MTEIVKASLENGIQKIRIRAEKGYHPAHIQLQKGIPAEITFHRA
                     TPSNCYKEILFEEEGILEPIGVDEEKVIRFTPQELGRHEFSCGMKMQKGSYIVVEKTR
                     KSLSLLQRFWITSIFTVPLVILMIGMLTGSISHQVMHWGTFLATTPIMLVAGKPYIQS
                     AWASFKKHNANMDTLVALGTLVAYFYSLVALFAGLPVYFESAGFILFFVLLGAVFEEK
                     MRKNTSQAVEKLLDLQAKTAEVLSDDSYVQVPLEQVKVGDLIRVRPGEKIAVDGVVVE
                     GVSSIDESMVTGESLPVDKTVGDTVIGSTINHSGTLVFRAEKVGSETVLAQIVDFVKK
                     AQTSRAPIQDLTDKISGIFVPVVVILGIMTFWVWFVLLRDSVVVLGASFVSSLLYGVA
                     VLIIACPCALGLATPTALMVGTGRSAKMGVLLKNGTVLQEIQKVQTLVFDKTGTLTEG
                     KPVVTDIIGDEVEVFGLAASLEDASQHPLAEAIVKRASEAGLEFQTVENFQSLHGKGV
                     SGRINGKQVLLGNAKMLDGMDISNTYQDKLEELEKEAKTVVFLAVDNEIKGLLALQDI
                     PKENAKLAISQLKKRGLRTVMLTGDNAGVARAIADQIGIEEVIAGVLPEEKAHEIHKL
                     QQSGKVAFVGDGINDAPALSVADVGIAMGAGTDIAIESADLVLTTNNLLGVVRAFDMS
                     KKTFHRILLNLFWAFIYNVVGIPIAAGVFSGVGLALNPELAGLAMAFSSVSVLTSSLL
                     LNFSKID"
     gene            complement(7629..8000)
                     /locus_tag="VQU30_000245"
     CDS             complement(7629..8000)
                     /locus_tag="VQU30_000245"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000932058.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cupredoxin domain-containing protein"
                     /protein_id="HET2446433.1"
                     /translation="MLNSIVTIICIALIAFILFWFFKKPEKSGQKAQQKNGYQEIRVE
                     VMGGYTPELIVLKKSVPARIVFDRKDPSPCLDQIVFPDFGVHANLPMGEEYVVEITPE
                     QVGEFGFACGMNMMHGKMIVE"
     gene            complement(8011..8406)
                     /locus_tag="VQU30_000246"
     CDS             complement(8011..8406)
                     /locus_tag="VQU30_000246"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004256226.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CopY/TcrY family copper transport repressor"
                     /protein_id="HET2446434.1"
                     /translation="MQISDAEWQVMKIIWMQGEQTSTDLIRVLAERFDWSKSTIQTLL
                     ARLVEKECLTRKKEGKSFVYSALLTLDQSRDLLVQDIKDKVCSRRIRNLLADLIVECE
                     FTQTDLEDLEAVISEKKSSAVTEVRCNCM"
     regulatory      8590..8688
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00059"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="TPP riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="thiamine pyrophosphate"
                     /db_xref="RFAM:RF00059"
     gene            8772..9563
                     /gene="thiD"
                     /locus_tag="VQU30_000247"
     CDS             8772..9563
                     /gene="thiD"
                     /locus_tag="VQU30_000247"
                     /EC_number="2.7.1.49"
                     /EC_number="2.7.4.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000221716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional hydroxymethylpyrimidine
                     kinase/phosphomethylpyrimidine kinase"
                     /protein_id="HET2446435.1"
                     /translation="MTYLPVALTIAGTDPSGGAGIMADLKSFQARDVYGMAVVTSLVA
                     QNTRGVQLIEHVSPQMLKAQLESVFSDIPPQAVKTGMLATTEIMEIIQPYLKKLDCPY
                     VLDPVMVATSGDALIDSSARDYLKTNLLPLATIITPNLPEAEEIVGFSIHDPEGMQRA
                     GRLILKEFGPQSVVIKGGHLKGGAKDFLFTKNEQFVWESPRIQTCHTHGTGCTFAAVI
                     TAELAKGKSLYQAVDKAKAFITKAIQDAPQLGHGSGPVNHTTFKD"
     gene            complement(9772..10404)
                     /locus_tag="VQU30_000248"
     CDS             complement(9772..10404)
                     /locus_tag="VQU30_000248"
                     /EC_number="2.5.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001078228.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine phosphate synthase"
                     /protein_id="HET2446436.1"
                     /translation="MNREALRLYLVTNRYQDSVESFLAKVETACRSGVTIVQLREKNL
                     TTNQYYQLAKQVKEITDAYQVPLIIDDRLDVCLAVDAAGLHIGDDELPVSVARKVLGP
                     EKILGVTAKTVKRALEAEKSGADYLGTGAIFPTTTKENAPITLISTLKTICQTVAIPV
                     VAIGGLTSENIDQLMGTGIAGVAVVRDLMQAEDIEAKTQAFLTKLHDILS"
     gene            complement(10397..11200)
                     /locus_tag="VQU30_000249"
     CDS             complement(10397..11200)
                     /locus_tag="VQU30_000249"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001155192.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxyethylthiazole kinase"
                     /protein_id="HET2446437.1"
                     /translation="MQALTNPFPIGSSSLIHCMTNEISCEMLANGILALGCKPVMADD
                     PREVLDFTKQSQALFINLGHLSAEKEKAIRMAASYANQSSLPMVVDAVGVTTSSIRKS
                     LVKDLLDYRPTVLKGNMSEIRSLVGLKHHGVGVDASAKDQETEDLLQVLKDWCQTYPG
                     MSFLVTGPKDLIVSENQVAVLENGCTELDWITGTGDLVGALTAVFLSQGKTGFEASCL
                     AVSYLNIAAEKIVVQGMGLEEFRYQVLNQLSLLRRDENWLDTIKGEVYE"
     gene            complement(11200..11724)
                     /gene="thiW"
                     /locus_tag="VQU30_000250"
     CDS             complement(11200..11724)
                     /gene="thiW"
                     /locus_tag="VQU30_000250"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001225563.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy coupling factor transporter S component
                     ThiW"
                     /protein_id="HET2446438.1"
                     /translation="MRKHQLQVHKLTILSMMIALDVVLTPIFRIEGMAPMSSVVNILA
                     GIMMGPVYALAMATVTAFIRMTTQGIPPLALTGATFGALLAGLFYKYGRKFYFSALGE
                     IVGTGIIGSIVSYPVMVLFTGSAAKLSWFIYTPRFFGATLIGTAISFIAFRFLIKQEF
                     FKKVQGYFFAERID"
     gene            complement(11729..12421)
                     /gene="tenA"
                     /locus_tag="VQU30_000251"
     CDS             complement(11729..12421)
                     /gene="tenA"
                     /locus_tag="VQU30_000251"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864194.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiaminase II"
                     /protein_id="HET2446439.1"
                     /translation="MEFTDIAMELSKKAWQASFHHPFILQLQEGNLEPAIFRYYLIQD
                     AYYLKAFSEIYHLLADKTSNQEMKRLLKQNAQGLVEGELFIRQQFFKELEINDQEMEQ
                     HPIAPTCYHYISHIYRQFAEPNLAIAFASLLPCPWLYHDIGKSLNLKPSPNPLYQQWI
                     ETYITDELEQQIREEGALVNQLYRESDETDKQKMLDAFHISVHMEAKFWEMAYQHQTW
                     KSDLQSLEKGEE"
     gene            complement(12432..13082)
                     /locus_tag="VQU30_000252"
     CDS             complement(12432..13082)
                     /locus_tag="VQU30_000252"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000241367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cobalt ABC transporter permease"
                     /protein_id="HET2446440.1"
                     /translation="MVKVATQTPIISLFLLILSLETSFIPSIALNLSVVAFCILFMLY
                     YRRFKMLAWMIILAIFPSFANYWAVQLHGDASQAVMLGTRAFVTVCIGLVFVSSISLK
                     ELLLYLAQKGLSRSWSYALIVVFNSFPLIQQEIKSLKEACLLRGQKLHFWSPLIYSKV
                     LMTVFRWRHLYLRALSAYGYDEHAQLKNSYRTFYIPKKTKLIYLLFFLLLQTSLFL"
     gene            complement(13084..14469)
                     /locus_tag="VQU30_000253"
     CDS             complement(13084..14469)
                     /locus_tag="VQU30_000253"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000522086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET2446441.1"
                     /translation="MGLELRAIQSPIFSEPFDFTFHAQAFTLLVGSSGSGKSSLFQMI
                     AQVSSLPYSGQVLIDGSEVSQLSIVERVQTVGILLQNPNHQFTMESLFEELVFTMENI
                     GYHLQEIDSKIAEVVQQCRCKDILHRLIHHLSGGEKQKAALAVLFAMNPRVYLLDEPF
                     ASIDRKSRIEILEILKELVYDGKTVILCDHDLSDYKAYIDHMVELRDGKLREVFQIPS
                     YEMTQVASKEVASSPELFHMNRVTGELGNRPLFSIADFTFYQGISCILGDNGVGKSTL
                     FRSILQFQKYKGSITWKGSVLKKKKSLYRDLTGVVQEAEKQFIRVSLREELQLDGPDS
                     ERNQRIFQALRYFDLEQAVDKSPYQLSGGQQKILQLLTILTSKASVILLDEPFAGLDD
                     RACHYFCKWIVEERNQGRSFLLISHRLDPLISVVDYWIEMTSQGLRHVKEVTITKPLT
                     SQSSNTQGEVR"
     gene            complement(14470..15030)
                     /locus_tag="VQU30_000254"
     CDS             complement(14470..15030)
                     /locus_tag="VQU30_000254"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000915269.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HET2446442.1"
                     /translation="MLKKWQLKDVILLAFLSIFFGGVFVGSGYVYNILSLLLTPLGLQ
                     AFANEILFGLWCMAAPIAAIFVPRVGSATIGEVLAALAEVLYGSQFGLGALLSGFVQG
                     LGSEFGFIVTKNRYESWLSLTANSIGITLVSFVYEYIKLGYYAFSLPFVLSLLVVRFI
                     SVYFFCTILVRAIVKLYHQFATGGKA"
     regulatory      complement(15292..15380)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00059"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="TPP riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="thiamine pyrophosphate"
                     /db_xref="RFAM:RF00059"
     gene            complement(15589..16218)
                     /locus_tag="VQU30_000255"
     CDS             complement(15589..16218)
                     /locus_tag="VQU30_000255"
                     /EC_number="2.5.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000468574.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine phosphate synthase"
                     /protein_id="HET2446443.1"
                     /translation="MFHKELLKLYFICGTTTCQGKNLYTVVEEALKGGITLFQFREKG
                     EGALEGLEKLELAIQIKELCKKYNVPFIVNDDIDLAMEIDADGVHVGQDDIGVDEIRK
                     LMPDKIIGLSIRNEEEFQQSKVEYVDYVGVGPVFGTQSKDDAGGTIGYEGLELMRKLL
                     PQMPLVAIGGIQTKHIKDIIKTNMDGVSIISAISYAKNIEKTVREMSEQ"
     gene            complement(16220..17002)
                     /gene="thiM"
                     /locus_tag="VQU30_000256"
     CDS             complement(16220..17002)
                     /gene="thiM"
                     /locus_tag="VQU30_000256"
                     /EC_number="2.7.1.50"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000202454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxyethylthiazole kinase"
                     /protein_id="HET2446444.1"
                     /translation="MTSLKLLKEKAPLVICITNDVVKNFTANGLVALGASPAMSEFPA
                     DLEDLLKYAGGLLINIGTLTDENWKLYQAALKIAEKYNVPAVLDPVACGAGEYRKKVA
                     DDLINNYKLAAIRGNAGEIASLVGIDVASKGVDSAGVDNIDEIALAANEKFNIPIVVT
                     GEVDAIAVNGEVVMIHNGSAMMPKVIGTGCLLGAVVASFIGLEKGQELKSLETAMLVY
                     NIAGEMAEKRPNGHLPGTFKVEFINALYEITDEDVKEFKRVK"
     gene            complement(17245..17913)
                     /locus_tag="VQU30_000257"
     CDS             complement(17245..17913)
                     /locus_tag="VQU30_000257"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000449895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TenA family protein"
                     /protein_id="HET2446445.1"
                     /translation="METQDYAFQPGLTVGELLKSSQKDWQAAINHRFVKELFAGTIEN
                     KVLKDYLIQDYHFFDAFLSMLGACVAHADKLESKLRFAKQLGFLEADEDGYFQKAFKE
                     LKVAENDYLEVTLHPVTKAFQDLMYSAVASSDYAHLLVMLVIAEGLYLDWGSKDLALP
                     EVYIHSEWINLHRGPFFAEWVQFLVDELNRVDKNREDLTELQQRWNQAVALELAFFDI
                     GYDV"
     regulatory      complement(18128..18216)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00059"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="TPP riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="thiamine pyrophosphate"
                     /db_xref="RFAM:RF00059"
     gene            complement(18470..19606)
                     /gene="lctO"
                     /locus_tag="VQU30_000258"
     CDS             complement(18470..19606)
                     /gene="lctO"
                     /locus_tag="VQU30_000258"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000120720.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-lactate oxidase"
                     /protein_id="HET2446446.1"
                     /translation="MSYKTSNAEGHVDFINTYDLEPMAQQVIPKAAFGYIASGAEDTF
                     TLRENIRAFNHKLIVPHTLCDVENPSTEIEFAGEKLSSPIIMAPVAAHKLANEQGEVA
                     TARGVHEFGSLYTTSSYSTVDLPEISEALQGTPHWFQFYFSKDDGINRHIMDRVKAEG
                     YKAIVLTADATVGGNREVDKRNGFVFPVGMPIVEEYLPEGAGKSMDFVYKSAKQRLSP
                     RDVEFIAEYSGLPVYVKGPQCREDVERSLAAGASGIWVTNHGGRQIDGGPAAFDSLQE
                     VAEAVDRRVPIVFDSGVRRGQHVFKALASGADLVAIGRPVIYGLALGGSVGVRQVFEH
                     LNAELKTVMQLSGAQTIEDVKHFKLRHNPYNPTFPVDPRDLKLY"
     gene            complement(20231..21721)
                     /gene="lysS"
                     /locus_tag="VQU30_000259"
     CDS             complement(20231..21721)
                     /gene="lysS"
                     /locus_tag="VQU30_000259"
                     /EC_number="6.1.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003055423.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lysine--tRNA ligase"
                     /protein_id="HET2446447.1"
                     /translation="MSTEHMEELNDQQIVRREKMAALREQGIDPFGKRFERTANSQEL
                     KDKYANLDKEQLHDKNETATIAGRLITKRGKGKVGFAHLQDREGQIQIYVRKDAVGEE
                     NYEIFKKADLGDFLGVEGEVMRTDMGELSIKATHITHLSKALRPLPEKFHGLTDVETI
                     YRKRYLDLISNRESFERFVTRSKIISEIRRYLDQKGFLEVETPVLHNEAGGAAARPFI
                     THHNAQNIDMVLRIATELHLKRLIVGGMERVYEIGRIFRNEGMDATHNPEFTSIEVYQ
                     AYADFQDIMDLTEGIIQHAAKSVKGDGPVNYQGTEIKINEPFKRVHMVDAIREITGVD
                     FWQDMTLEEAKTIAAEKKVPVEKHYTEVGHIINAFFEEFVEETLIQPTFVYGHPVAVS
                     PLAKKNPEDQRFTDRFELFIMTKEYGNAFTELNDPIDQLSRFEAQAKAKELGDDEATG
                     IDYDYIEALEYGMPPTGGLGIGIDRLCMLLTDTTTIRDVLLFPTMK"
     gene            complement(21849..21995)
                     /locus_tag="VQU30_000260"
     CDS             complement(21849..21995)
                     /locus_tag="VQU30_000260"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000120724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactate oxidase"
                     /protein_id="HET2446448.1"
                     /translation="MSYKTSNAEGHVDFINTYDLEPMAQQVIPKAAFGYIASGAGDTF
                     TSFQ"
     gene            22221..22889
                     /locus_tag="VQU30_000261"
     CDS             22221..22889
                     /locus_tag="VQU30_000261"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006531263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HET2446449.1"
                     /translation="MVEQYLPLYQKAFFLTLHIAVWGILGSFLLGLIVSIIRHYRILV
                     LAQVATAYIELSRNTPLLIQLFFLYFGLPRIGIVLSSEVCATLGLVFLGGSYMAESFR
                     SGLEAISQTQQEIGLAIGLTPLQVFYYVVLPQATAVALPSFSANVIFLIKETSVFSAV
                     ALADLMYVAKDLIGLYYETDIALAMLVVAYLIMLLPISLVFSWIERRLRHAGFGNPST
                     LSRK"
     gene            22849..23526
                     /locus_tag="VQU30_000262"
     CDS             22849..23526
                     /locus_tag="VQU30_000262"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001154125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HET2446450.1"
                     /translation="MQDSGIQVLFQGNNLLRILQGLGVTIEISILSVLLSMMFGTVMG
                     IIMTSHSRIIRFLTRLYLDFTRIMPQLVLLFIVYFGLARNFNINISGETSAIIVFTLW
                     GAAEMGDLVRGAITSLPKHQFESGQALGLTNVQLYYHIIIPQVLRRLLPQAINLVTRM
                     IKTTSLVVLIGVVEVTKVGQQIIDSNRLTIPTASFWIYGTILVLYFAVCYPISKLSTH
                     LEKHWRN"
     gene            23527..24284
                     /locus_tag="VQU30_000263"
                     /pseudo
     CDS             23527..24284
                     /locus_tag="VQU30_000263"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012000401.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
     gene            24296..25157
                     /locus_tag="VQU30_000264"
                     /pseudo
     CDS             24296..25157
                     /locus_tag="VQU30_000264"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000765255.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine ABC transporter substrate-binding
                     protein"
     gene            complement(25237..25884)
                     /locus_tag="VQU30_000265"
     CDS             complement(25237..25884)
                     /locus_tag="VQU30_000265"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001002414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET2446451.1"
                     /translation="MNEIIILKNIELKLKKTCVFQNLNFSCKQGEIIGITGANGSGKS
                     VLFKLIAGLYSPSYGEVLINGENIVPERKIPANLGALIEEPGFINYYSGFKNLQYLAS
                     IRGVVGNQEINDTLKIVGLYEQKDQKVKTYSLGMRKKLGIAQAIMENPSILLLDEPMN
                     ALDKSSVENMRTLFRKLSSEKGTTILIASHSEEDIRILCDKVYAIEDKVCTLCSD"
     gene            complement(25881..26579)
                     /locus_tag="VQU30_000266"
     CDS             complement(25881..26579)
                     /locus_tag="VQU30_000266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000517353.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2446452.1"
                     /translation="MGKLSSHMWRLNKIIYTKYFWGYVLFWILICLGLWYWLEGNDRL
                     VIEILKGPNLSQNSFLVLSIWLLHWFIIHTFFLAVVYRRRASDFFMEVIRFSSIKLWI
                     RYQIWTCFLYGLILIMVKVLVIQFMLQLPNWDIGVLFIVDSLNACVLVLFCFMLYALG
                     ANVQMNFACVSFFLLMIVFGGLFVGNRTNYLFYILNRGNGDVGGDLFLQLLFLVFLFQ
                     SIFYFTRQKRRFIE"
     gene            complement(26589..27341)
                     /locus_tag="VQU30_000267"
     CDS             complement(26589..27341)
                     /locus_tag="VQU30_000267"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2446453.1"
                     /translation="MKQFVQFYKKDFLSVLVYFILLLSCVLSSTVYLLRCRQYSIHPN
                     VLEWILVLLQDMTTGVYCFPFTYILFFFYLMNNYFNRLECRIRLKSIKHFTSFSFKLA
                     ALSTGIWTATLFLLIFLIAFSNGFSFSLEIKEVDFLREFYGISIANNASFFIGFFFSY
                     IAYYFFLSLLTISSFSWFKKSNMSLVFLFTFLFVESLFWIYQLNNGIIGLLPIFQYMV
                     NSNPYALIYWLTLLSIIIPLTVFSVHRNWRRV"
     gene            complement(27341..28105)
                     /locus_tag="VQU30_000268"
     CDS             complement(27341..28105)
                     /locus_tag="VQU30_000268"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000394067.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2446454.1"
                     /translation="MEFFICNLVRVVQSPRFYMSLFLTLLCMSLGNFLAFNGIYKIEG
                     LSIFFAASSIRGFSPISLVAALICTLPYSSQIIEDAESHFLTAQLCRISKKKYLAIVG
                     STAIISSFLVFFLPYLLLLGINLLVTPYQEIYIGDYSGALKELFDSNQLLYSLVTTLW
                     YGVWGAVFSIFGLASALLVKKKIGAIFIPVAYMMVGGIFWAILGLSYLEPVTTLALGY
                     QKDISLSLVSGHLAFILFVSCLVVYGTFFLHSEDYV"
     gene            complement(28201..28604)
                     /locus_tag="VQU30_000269"
                     /pseudo
     CDS             complement(28201..28604)
                     /locus_tag="VQU30_000269"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000829085.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(28784..29416)
                     /locus_tag="VQU30_000270"
     CDS             complement(28784..29416)
                     /locus_tag="VQU30_000270"
                     /EC_number="2.4.2.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000170913.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="orotate phosphoribosyltransferase"
                     /protein_id="HET2446455.1"
                     /translation="MTLAKDIASHLLKIQAVYLKPEEPFTWASGIKSPIYTDNRVTLA
                     YPETRTLIENGFVEAIKEAFPEVEVIAGTATAGIPHGAIIADKMDLPFAYIRSKPKDH
                     GAGNQIEGRVAQGQKMVVVEDLISTGGSVLEAVAAAKREGADVLGVVAIFSYQLPKAD
                     KNFADAGVKLVTLSNYRELIHLAQEEGYITPEGLDLLKRFKEDQENWQEG"
     gene            complement(29450..30151)
                     /gene="pyrF"
                     /locus_tag="VQU30_000271"
     CDS             complement(29450..30151)
                     /gene="pyrF"
                     /locus_tag="VQU30_000271"
                     /EC_number="4.1.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001206708.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="orotidine-5'-phosphate decarboxylase"
                     /protein_id="HET2446456.1"
                     /translation="MREHRPIIALDFPSFEAVKEFLALFPAEESLYLKVGMELYYAAG
                     PEIVSYLKGLGHSVFLDLKLHDIPNTVKSAMKVLSQLGVDMTNVHAAGGVEMMKAARE
                     GLGSQAKLIAVTQLTSTSEAQMQEFQNIQTSLQESVIHYAKKTAEAGLDGVVCSAQEV
                     QVIKQATNPDFICLTPGIRPAGVAVGDQKRVMTPADAYQIGSDYIVVGRPITQAEDPV
                     AAYHAIKDEWTQNWN"
     gene            30472..30564
                     /locus_tag="VQU30_000272"
                     /pseudo
     CDS             30472..30564
                     /locus_tag="VQU30_000272"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011516271.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
     gene            complement(30886..31599)
                     /locus_tag="VQU30_000273"
     CDS             complement(30886..31599)
                     /locus_tag="VQU30_000273"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303284.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HET2446457.1"
                     /translation="MLKRFLALVWLRCQIILSNKSILLQVLVPFAFTYFYKYLMETQG
                     KVNDQQALVLLMMCLPFSLALAVGSPITIILSEEKEKYNLQTLLLSGVKGSEYILSTM
                     FLPFLLTFVIMGTTPLILGVTIVHTFNYITIVLLTSLSIILFYLLIGLTAKSQVVAQV
                     ISLPAMILVAFLPMLSGLDKTVAKITDYSFMGLFTKFFTKWEGFSWNKTLIPNLTLLI
                     WIVLLLTLITITIRKKKIS"
     gene            complement(31592..32287)
                     /locus_tag="VQU30_000274"
     CDS             complement(31592..32287)
                     /locus_tag="VQU30_000274"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000529917.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET2446458.1"
                     /translation="MTGQFLADKGQSIILGQKSQNLTSGELKRIGLVSDTSGFYEKMS
                     LYNNLLFYSKFYNISKSRVDNLLKRVGLYDSRKMVAGKLSTGMRQRMLLARALINKPA
                     VLFLDEPTSGLDPTTSRTIHELILELKTAGTTIFLTTHDMNEATLLCDYVALLNKGKL
                     VEQGAPSELIQRYNKDKKIKVTDYNGNQITFDFTSLEQVSQADLENIFSIHSCEPTLE
                     DIFITLTGGKLNA"
     gene            complement(32627..33959)
                     /locus_tag="VQU30_000275"
                     /pseudo
     CDS             complement(32627..33959)
                     /locus_tag="VQU30_000275"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812020.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ThiF family adenylyltransferase"
     gene            complement(33943..34741)
                     /locus_tag="VQU30_000276"
                     /pseudo
     CDS             complement(33943..34741)
                     /locus_tag="VQU30_000276"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001824573.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase M50 family protein"
     gene            complement(35531..36730)
                     /gene="divIB"
                     /locus_tag="VQU30_000277"
     CDS             complement(35531..36730)
                     /gene="divIB"
                     /locus_tag="VQU30_000277"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000031166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein DivIB"
                     /protein_id="HET2446459.1"
                     /translation="MSKDKKNEDKEILEELKELSEWQKRNQEYLKKKAEEEAALAEEK
                     EKERQARMGEESEKSEDKQDQESETDQEDSESAKEESEEKVASSEADKEKEEKEEPES
                     KEKEEQDKKLSKKATKEKPAKAKIPGIHILRAFTILFPSLLLLIVSAYLLSPYATMKD
                     IRVEGTVQTTADDIRQASGIQDSDYTINLLLDKAKYEKQIKSNYWVESAQLVYQFPTK
                     FTIKVKEYDIVAYYISGENHYPILSSGQLETSSVSLNSLPETYLSVLFNDSEQIKVFV
                     SELAQISPELKAAIQKVELAPSKVTSDLIRLTMNDSDEVLVPLSEMSKKLPYYSKIKP
                     QLSEPSVVDMEAGIYSYTVADKLIMEAEEKAKQEAKEAEKKQEEEQKKQEEESNRNQT
                     TQRSSRR"
     gene            complement(36740..37798)
                     /locus_tag="VQU30_000278"
     CDS             complement(36740..37798)
                     /locus_tag="VQU30_000278"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000724845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine--N-acetylmuramyl-
                     (pentapeptide) pyrophosphoryl-undecaprenol
                     N-acetylglucosamine transferase"
                     /protein_id="HET2446460.1"
                     /translation="MKKIVFTGGGTVGHVTLNLLLMPKFIEDGWEVHYIGDKRGIEHQ
                     EILKSGLDVTFHSIATGKLRRYFSWQNMLDVFKVCWGIVQSLFIMLRLRPQTLFSKGG
                     FVSVPPVIAARVSGVPVFIHESDLSMGLANKIAYKFATKMYSTFEQASSLSKVEHVGA
                     VAKVSDQKNPEPDELVDIQSHFNHKLPTVLFVGGSAGARVFNQLVTDHKKELTERYNI
                     INLTGDSSLNELSQNLFRVDYVTDLYQPLMELADIVVTRGGANTIFELLAIAKLHVIV
                     PLGREASRGDQLENAAYFVKKGYAEDLQESDLTLDSLEEKLSHLLSHKEDYQAKMKAS
                     KELKSLADFYQLLKKDLS"
     gene            complement(37800..39152)
                     /locus_tag="VQU30_000279"
     CDS             complement(37800..39152)
                     /locus_tag="VQU30_000279"
                     /EC_number="6.3.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000862950.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-L-alanine--D-glutamate
                     ligase"
                     /protein_id="HET2446461.1"
                     /translation="MKVIDQFKNKKVLVLGLAKSGESAARLLDKLGAIVTVNDGKPFE
                     DNPAAQSLLEEGIKVITGGHPLELLDEEFALMVKNPGIPYNNPMIEKALAKGIPVLTE
                     VELAYLISEAPIIGITGSNGKTTTTTMIGEVLTAAGQHGLLSGNIGYPASQVAQIASD
                     KDTLVMELSSFQLMGVQEFHPEIAVITNLMPTHIDYHGSFSEYVAAKWNIQNKMTAAD
                     FLVLNFNQDLAKDLTSKTEATVVPFSTLEKVDGAYLEDGQLYFRGEVVMAANEIGVPG
                     SHNVENALATIAVAKLRGVDNQTIKETLSAFGGVKHRLQFVDDIKGVKFYNDSKSTNI
                     LATQKALSGFDNSKVVLIAGGLDRGNEFDELVPDITGLKKMVILGQSAERVKRAADKA
                     GVAYVEATDIADATRKAYELATQGDVVLLSPANASWDMYANFEVRGDLFIDTVAELKE
                     "
     gene            complement(39256..39897)
                     /locus_tag="VQU30_000280"
     CDS             complement(39256..39897)
                     /locus_tag="VQU30_000280"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000571297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET2446462.1"
                     /translation="MIELKNISKKFGSRQLFSDTNLHFEGGKIYALIGTSGCGKTTFL
                     NMIGRLEPYDKGQIIYDGTSLKDIKPSVFFRDYLGYLFQDFGLIESQTVKENLNLGLV
                     GKKLKEKEKISLMKQALNCVNLSYLDLKQPIFELSGGEAQRVALAKIILKDPPLILAD
                     EPTTSLDPKNSEELLSILESLKNPNRTIIIATHNPLIWEQVDQVIRVTDLSHR"
     gene            complement(39899..41920)
                     /locus_tag="VQU30_000281"
     CDS             complement(39899..41920)
                     /locus_tag="VQU30_000281"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000732428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin-associated integral membrane family
                     protein"
                     /protein_id="HET2446463.1"
                     /translation="MKKLFILLSTFFLSFFLAWIIVLRAPQYLYASYDSVSLLRVKKD
                     TQEPTREVFEQELENFANSEQSLIARRIVEPSKDGTTHFTYATYGQGTLPKEFQEASQ
                     ESRERSDPLNSYLLLSGSLTKEKLADKLGDLGYKASADRKIPPYFLAFRILLNPLILI
                     SLAIFGLSFFALVIITRIKEMRAAGIKLFSGQTLLSIMGHSLSTDIKWLLLSALLSFL
                     GGGVVLFSQGLFYPILLATYGFGISFYLLFLLAISILLMLLYLMSLSYKALVPVIKGR
                     LPLKRLMILTLLCQLVAVFTVGYAVKTGLMSYQRLKELEISKQAWQDRADYYQISFGL
                     GDRGKDTENQSKWYAFAKEAIEEEQALYVKDNLLHFANPQGKNEQGETLDTYSPDANT
                     LYVSPSYLDKEKVVVDAETKQKLAHLQKGEFILLLPEHLRSREAELKKVFEERLSYYG
                     KSGEEASAPLDYEMKAHVSYLSMGEKRFVYNNGENPVSTQYLTDPILVVFTPTSTGDS
                     FISLSSWSINAGKQLFIKGYESGLELLKKAGIYEQVSYLKEGRSVYLTRYNEVQTETA
                     TLILGAIVGIASSLLLFYSVNLLYFEQFRRDILIKRISGLRFFETHAQYMVSQFASFV
                     FGASLFILSSRDLVIGLLTLLVFLASAVLTLYRQAQKESRVSMTIMKGK"
     gene            complement(41991..42290)
                     /locus_tag="VQU30_000282"
     CDS             complement(41991..42290)
                     /locus_tag="VQU30_000282"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactococcin 972 family bacteriocin"
                     /protein_id="HET2446464.1"
                     /translation="MKTKKHRLLALALISSFTLLGAASAAVQYPDGGVWTYGEGSGGG
                     WAFSNYYHGKKYHYSSLVSRWNSHSDKGEASAGKTSYAWIWTKWGEQVAFYCDYD"
     gene            complement(42656..42910)
                     /locus_tag="VQU30_000283"
     CDS             complement(42656..42910)
                     /locus_tag="VQU30_000283"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000262800.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3165 family protein"
                     /protein_id="HET2446465.1"
                     /translation="MVYLVLGILLLLLYVFATPESIKGTVNIVAMVCILVALLILLVL
                     SFLKIFQLPTEIFLAIAMLILAYFSVRDITLMPVKKSKRR"
     gene            complement(42930..44771)
                     /gene="typA"
                     /locus_tag="VQU30_000284"
     CDS             complement(42930..44771)
                     /gene="typA"
                     /locus_tag="VQU30_000284"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003078415.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translational GTPase TypA"
                     /protein_id="HET2446466.1"
                     /translation="MTKLREDIRNIAIIAHVDHGKTTLVDELLKQSETLDARTELAER
                     AMDSNDIEKERGITILAKNTAVAYNGTRINIMDTPGHADFGGEVERIMKMVDGVVLVV
                     DAYEGTMPQTRFVLKKALEQDLVPIVVVNKIDKPSARPAEVVDEVLELFIELGADDDQ
                     LDFPVVYASAINGTSSLSDDPADQEATMAPIFDTIIDHIPAPVDNSDEPLQFQVSLLD
                     YNDFVGRIGIGRVFRGTVKVGDQVTLSKLDGTTKNFRVTKLFGFFGLERREIQEAKAG
                     DLIAVSGMEDIFVGETITPTDAVEALPILHIDEPTLQMTFLVNNSPFAGKEGKWVTSR
                     KVEERLQAELQTDVSLRVDPTDSPDKWTVSGRGELHLSILIETMRREGYELQVSRPEV
                     IVKEIDGVKCEPFERVQIDTPEEYQGSVIQSLSERKGEMLDMISTGNGQTRLVFLVPA
                     RGLIGYSTEFLSMTRGYGIMNHTFDQYLPLIPGEIGGRHRGALVSIDAGKATTYSIMS
                     IEERGTIFVNPGTEVYEGMIIGENSRENDLTVNITKAKQMTNVRSATKDQTAVIKTPR
                     ILTLEESLEFLNDDEYMEVTPESIRLRKQILNKAEREKANKKKKSAE"
     gene            44933..45658
                     /locus_tag="VQU30_000285"
     CDS             44933..45658
                     /locus_tag="VQU30_000285"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001235004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA pseudouridine(516) synthase"
                     /protein_id="HET2446467.1"
                     /translation="MRLDNLLAQEKVSRKAMKQALLRGEILVDGCPARSLAQNIDTGL
                     QELLFQDRIIQGYEHTYLMLHKPAGVVTANKDKELPTVMDLLPSDIQSDKLYAVGRLD
                     RDTTGLLLLTDNGPLGFQLLHPQYHVDKTYQVQVNELLTPDHIQAFQKGIVFLDGTVC
                     KPAKLEILSASPSLSQASITISEGKFHQIKKMFLSVGVKVTSLKRIQFGDFTLNPDLA
                     ESNYRPLNQKELQIIKNYLEMSR"
     gene            complement(45698..45925)
                     /locus_tag="VQU30_000286"
     CDS             complement(45698..45925)
                     /locus_tag="VQU30_000286"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000660075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2446468.1"
                     /translation="MKEKKKNPLFVGILSIILGLLFPIVGLILGIIGLVLAISYQKES
                     QLDYKIEKILNILGIVISVVNWIVAIALIFR"
     gene            complement(46014..46394)
                     /locus_tag="VQU30_000287"
     CDS             complement(46014..46394)
                     /locus_tag="VQU30_000287"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-like domain-containing protein"
                     /protein_id="HET2446469.1"
                     /translation="MVTWILWALILAMLAWMGFNYLRIRRAAKIVDNEEFEALIRTGQ
                     LIDLRDPAEFHRKHILGARNIPSSQLKTSLAALRKDKPVLLYENQRAQRVTNAALYLK
                     KQGFSEIYILSYGLDSWKGKVKTS"
     gene            complement(46394..46663)
                     /locus_tag="VQU30_000288"
     CDS             complement(46394..46663)
                     /locus_tag="VQU30_000288"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000051789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YqgQ family protein"
                     /protein_id="HET2446470.1"
                     /translation="MSLFLKKTQNFARMSLMKTFYDVQQFLKRFGIIVYMGKRLYDIE
                     LMKLELSRIYDAGLMDKLDYLEAEAVLRREHKVELDYIEKNGEKN"
     gene            46727..47635
                     /locus_tag="VQU30_000289"
     CDS             46727..47635
                     /locus_tag="VQU30_000289"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HET2446471.1"
                     /translation="MRIQQLHYIIKIVETGSMNEAAKQLFITQPSLSNAVRDLENEMG
                     IEIFIRNPKGITLTRDGMEFLSYARQVVEQTQLLEERYKNPVAHRELFSVSSQHYAFV
                     VNAFVSLLKKSDMEKYELFLRETRTWEIIDDVKNFRSEVGVLFLNSYNRDVLTKMLDD
                     NHLLAHHLFTAQPHIFVSKTNPLAKKDKVKLSDLENFPYLSYDQGTHNSFYFSEEILS
                     QEHHKKSIVVSDRATLFNLLIGLDGYTIATGILNSNLNGDNIVSIPLDIDDPIELVYI
                     QHEKTSLSKMGERFIDYLLEEVQFDS"
     gene            complement(47689..48444)
                     /locus_tag="VQU30_000290"
     CDS             complement(47689..48444)
                     /locus_tag="VQU30_000290"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001142149.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HET2446472.1"
                     /translation="MPTILITGASGGLAQEMVKLLPNDQLILLGRNKEKLAQLYGNYS
                     HAELIEIDITDDSALEALVTDLYLRYGKIDVLINNAGYGIFEGFDQIADKDIHQMFEV
                     NTFALMNLSRHLAARMKESSKGHIINIVSMAGLIATGKSSLYSATKFAAIGFSNALRL
                     ELMPYGVYVTTVNPGPIRTGFFDQADPDGTYLKSVDRFLLEADAVAKKIVKIIGKNKR
                     ELNLPILLNLAHKFYTLFPKLADKLAGETFNYK"
     gene            complement(48465..49394)
                     /locus_tag="VQU30_000291"
     CDS             complement(48465..49394)
                     /locus_tag="VQU30_000291"
                     /EC_number="3.1.26.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000354350.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease Z"
                     /protein_id="HET2446473.1"
                     /translation="MDIQFLGTGAGQPSKARNVSSLALKLLDEINEVWLFDCGEGTQN
                     RILETTIRPRKVSKIFITHLHGDHIFGLPGFLSSRAFQANEEQTDLEIYGPQGIKSFV
                     LTSLRVSGSRLPYRIHFHEFDQDSLGKILETDKFTVYAEELDHTIFCVGYRVMQKDLE
                     GTLDAEKLKAAGVPFGPLFGKIKNGQDLVLEDGTEIKAADYISAPRPGKIITILGDTR
                     KTDASVRLAVNADVLVHESTYGKGDEKIARNHGHSTNMQAAQVAVEAGAKRLLLNHIS
                     ARFLSKDISKLKKDAATIFENVHVVKDLEEVEI"
     gene            complement(49409..50032)
                     /locus_tag="VQU30_000292"
     CDS             complement(49409..50032)
                     /locus_tag="VQU30_000292"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cystathionine beta-lyase"
                     /protein_id="HET2446474.1"
                     /translation="MTDIKTLALKYGGYTSLDKVYLDQLLAGKTEQEQLTLITPPPSV
                     VNAYFAELYQKKSPQAATDYFAELSQELNLYNTEPSFTLENKPFIRLNLSGKSFGFCY
                     ESDGFGRIFSENEEKISDDLLFEIAQIFSHQLVFEESGKIYMKPVKDEEVVSLESLTA
                     LTDLERLADGRKRLKGYSQEDLLQEAAAFSGKRYFRSENRTAMLYID"
     gene            complement(50025..51263)
                     /gene="hflX"
                     /locus_tag="VQU30_000293"
     CDS             complement(50025..51263)
                     /gene="hflX"
                     /locus_tag="VQU30_000293"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000573186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase HflX"
                     /protein_id="HET2446475.1"
                     /translation="MIETEKKEERVLLIGVELQGMDSFDLSMEELASLAKTAGAVVVD
                     SYRQKREKYDSKTFVGSGKLEEIALMVDAEEITTVIVNNRLTPRQNVNLEEVLGVKVI
                     DRMQLILDIFAMRARSHEGKLQVHLAQLKYLLPRLVGQGIMLSRQAGGIGSRGPGESQ
                     LELNRRSVRNQITDIERQLKVVEKNRATVREKRLESSTFKIGLIGYTNAGKSTIMNIL
                     TSKTQYEADELFATLDATTKSIHLGGNLQVTLTDTVGFIQDLPTELVSSFKSTLEESK
                     HVDLLVHVIDASNPYHEEHEKTVLSIMKDLDMEDIPHLTLYNKADLVEDFTPTQTPYT
                     LISAKSEDSRENLQALLLDKIKEIFEAFTLRVPFSKSYKIHDLESVAILEERDYQEDG
                     EVITGYISEKNKWRLEEFYD"
     gene            complement(51256..52140)
                     /gene="miaA"
                     /locus_tag="VQU30_000294"
     CDS             complement(51256..52140)
                     /gene="miaA"
                     /locus_tag="VQU30_000294"
                     /EC_number="2.5.1.75"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000850191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (adenosine(37)-N6)-dimethylallyltransferase
                     MiaA"
                     /protein_id="HET2446476.1"
                     /translation="MKTKIIVIVGPTAVGKTALAIEVAKCFNGEVVSGDSQQVYRGLD
                     IGTAKASPEEQAAVPHHLIDVREITESYSAFDFVSEAKMTIEDIHSRGKLAIIAGGTG
                     LYIQSLLEGYHLGGETPHEEILAYRASLEPYSDEELAHLVEQAGLEIPQFNRRRAMRA
                     LEIAHFGQDLENQEILYEPLIICLDDERSQLYERINHRVDLMFEAGLLDEAKWLFDHS
                     PNVQAAKGIGYKELFPYFRGEQTLEEARESLKQATRRFAKRQLTWFRNRMQVTFYQIG
                     ESGVQDRILSQIEEFLDD"
     gene            52261..52431
                     /locus_tag="VQU30_000295"
     CDS             52261..52431
                     /locus_tag="VQU30_000295"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001051775.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3042 family protein"
                     /protein_id="HET2446477.1"
                     /translation="MAKGFAKGLVTGVAGTVAAVAGAVYAFKKKVIEPEEQKAAFIEE
                     NRKKAARRRVSR"
     gene            complement(52479..53318)
                     /locus_tag="VQU30_000296"
     CDS             complement(52479..53318)
                     /locus_tag="VQU30_000296"
                     /EC_number="2.1.1.45"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003011065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thymidylate synthase"
                     /protein_id="HET2446478.1"
                     /translation="MTKADTIFKENIERILKEGVFSEQARPKYKDGTVANSKYVTGAF
                     SEYDLSKGEFPIITLRPIAIKSAIKEVLWIYQDQSNSLEVLNDKYNVHYWNDWEVGDT
                     GTIGERYGAVVKKHDIINKLLKQLETNPWNRRNIISLWDYQAFEETDGLLPCAFQTMF
                     DVRRVDGEIYLDATLTQRSNDMLVAHHINAMQYVALQMMIAKHFGWKVGKFFYFINNL
                     HIYDNQFEQAQELLRREPSNCQPRLVLNVPDGTNFFDIKAEDFELVDYDPVKPQLKFD
                     LAI"
     gene            complement(53415..54374)
                     /locus_tag="VQU30_000297"
     CDS             complement(53415..54374)
                     /locus_tag="VQU30_000297"
                     /EC_number="2.7.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002919069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family glucokinase"
                     /protein_id="HET2446479.1"
                     /translation="MSQKIIGIDLGGTSIKFAILTTAGEIQGKWSIKTNILDEGSHIV
                     DDMIESIQHRLDLLGLAAADFQGIGMGSPGVVDRDKGTVIGAYNLNWKTLQPIKQKIE
                     KALGIPFFIDNDANVAALGERWMGAGDNQPDVVFMTLGTGVGGGIVAEGKLLHGVAGA
                     AGELGHITVDFDQPISCTCGKKGCLETVASATGIVNLTRRYADEYEGDAALKRLIDNG
                     EEVTAKTVFDLAKEGDDLALIVYRNFSRYLGIACANIGSILNPSTIVIGGGVSAAGEF
                     LLQGVQKVYDENTFPQVRTSTKLALATLGNDAGVIGAASLVLQ"
     gene            complement(54501..55499)
                     /locus_tag="VQU30_000298"
     CDS             complement(54501..55499)
                     /locus_tag="VQU30_000298"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001042519.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase family
                     protein"
                     /protein_id="HET2446480.1"
                     /translation="MNKRLFLKMSLVTLPILALFSQPVLAEENIHFSSCKEAWANGYS
                     DLHEGEPGYSAKLDRDHDGVACELKNAPKGAFKAKQAATTQTDTTSSTASGWVKQDGS
                     WYYFDGNGNLVKNAWQGNYYLKADGKMAQSEWIYDSSYQAWYYLKSDGSYAKNAWQGA
                     YYLKSNGKMAQGEWVYDSSYQAWYYLKSDGSYARNAWQGNYYLKSDGKMAKGEWVYDA
                     TYQAWYYLTSDGSYAYSTWQGNYYLKSDGKMAVNEWVDGGRYYVGADGVWKEGQASTA
                     SSSNDSNSEYSAALGKAKSYNSLFHMSKKRMYRQLTSDFDKFSNDAAQYAIDHLDG"
     gene            complement(55549..56166)
                     /locus_tag="VQU30_000299"
     CDS             complement(55549..56166)
                     /locus_tag="VQU30_000299"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000766583.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HET2446481.1"
                     /translation="MKLIFLHGLGQSAESWKEVRNLLTDYPSEAIELFPSGVSNYQQA
                     KERVYQHLAQETEPFVLIGLSLGAALTLELSSYDLPNLRALILSGCPLKLAGNILFYL
                     QLLIFKLLPKRVFEKQGADKTLMVGVSEELKTLDLTDIAGTCSYPTLLICGSKDKPNL
                     SSMKALHRLLTDSQFQIIPDGPHVLNKAKPKEFVEKTRSFLELLK"
     gene            complement(56167..57888)
                     /gene="pabB"
                     /locus_tag="VQU30_000300"
     CDS             complement(56167..57888)
                     /gene="pabB"
                     /locus_tag="VQU30_000300"
                     /EC_number="2.6.1.85"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001818774.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminodeoxychorismate synthase component I"
                     /protein_id="HET2446482.1"
                     /translation="MHRKTVIDFRTLGERYTFAQPIKELKTRNVEEVADLLAQVESYQ
                     EQGYYVVGYVSYEAAPAFEEKLAVHKDPLLGEYLLYFTVHDSVETSPIPLTYEDIDLP
                     SNWQEVTSAADYEKAIAQIHHHLRQGDTYQVNYTVQLKQKLSANPFAIYNRMVVEQEA
                     GYNAYVEHDEMAVISMSPELFFEQNDRELTTRPMKGTTQRGVTDQEDLEQASWLEQDP
                     KNRSENMMIVDLLRNDMNRISEVGSEHVERLCQVEQYSTVWQMTSTIKSQLREDVDLV
                     EIFRSLFPCGSITGAPKIATMEIIKDLEPQPRGVYCGTIGLLLPNGRRIFNVAIRTIQ
                     LHKGQAIYGVGGGITWDSTWESEYREVHQKAAVLYRKQARFQLITTGEISQKNLLFED
                     QHLERLRKASRYFAFPFDAEDLGHKIEEECQDCEANRDYRLRISLSKSGEIEVNRQVL
                     TPLSTSFCQAQVCLQEAALNQSFTYFKTTHRPHLSLGEQEKIYHNKSGELLETSIGNL
                     VLKIAGKLYTPPIRLGILPGIYRQYLLETGQVEEKVLTLADLTQAEAIYGCNAVRGLY
                     ELSLEEN"
     gene            complement(57957..63644)
                     /locus_tag="VQU30_000301"
     CDS             complement(57957..63644)
                     /locus_tag="VQU30_000301"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000473008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="G5 domain-containing protein"
                     /protein_id="HET2446483.1"
                     /translation="MFKKDRFSIRKIKGVVGSVFLGSLLMAPSVVDAATYHYVNKEII
                     SQEAKDLIQTGKPDRNEVVYGLVYQKDQLPQTGTEASVLTAFGLLTVGSLLLIYKRKK
                     IASVFLVGAMGLVVLPSAGAVDPVATLALASREGVVEMDGYRYVGYLSGDILKTLGLD
                     TVLEETSAKPGEVTVVEVETPQSTTNQEQARTENQVVETEETPKEEAPRTEESPKEEP
                     KSEVKPTDDTLPKVEEGKEDSAEPAPVEEVGGEVESKSEEKVAVKPESQPSDKPAEES
                     KVEPPVEQAKVPEQPVQPTQAEQPSTPKESSQEDNPKEDRGAEETPKQEESTPDTKAE
                     ETVEPKEETKTAKGTQEEDYVGEALVPEQLPEYKVTEGTLVEESTTELDYKTETTEDP
                     TKYTDEETVLRNGEKGSQVTKTTYKTIGGVKTDQVLSTSTEVTKEPVNQQVIRGTKPI
                     EGTTVETREEIIPFETKEQEDDTLKRGTRQVTQEGVNDKKQITETYKTIRGEKTSDAP
                     TITETVIEKPQDKIIKNGTKELEKPTLEWAKTDKDVLKKSATASYTLTKPAGVEIKSI
                     KVALKDNTGTVVKEVTVEENNLQATLDNLKYYQGYTLSTTMVYDRGNGEETEILEDKE
                     VQLDLKKVEIKDIKETRLMKVDENGNETDSSLLETVPENLTSYYLKITTNHNKVTRLA
                     ITNIEEVTEEETSLFKVTASAPDLIQRDSNNSLSQTYTYYIEKPKASQNNVYYNFKDL
                     VDAMQKNPNGEFKLGSDLNATNVPTPSKSYVTGKFTGHLTSVDGKHFSIHNTARPLFD
                     RVEGGSIKNINLINVNINMPWANQLASLAQTVKNATVENIKVTGTIVGNNNVAGILDK
                     LDDAGIMTNVAFIGKVQSVGDKGWNLAGIASEIYRGNLNKAYADVELKGLNTRAGAIV
                     GHLAHDFNPRDVGAWSNVRNSVAKGTIDVARGDVGGLIGKDWPWGTIDNNISLVNVKR
                     GDIFFGSNDMDDEFVSNWIKPNNATVIGVSSGDKTHKQSSKIKEISQVEADKKIKDMG
                     ITADTFEVTEHLVDKLNRRILRDEEYKTIQDYNANRELVYRNVEKLQPFYNKEWIVNQ
                     GNKLTTDSPLMNKEVLSVTAMKGNDFITDLTDADHIMVHYADKTKDIFTISPKDSQVK
                     QVKEYSVAELGEVVYTPNMVVKDRADLISAIEGILSPIELQSDPIYQRLGRTGDNRVN
                     AIKNLYLEESFKEVKDHLNTFVTKLVENEDHQLNTDEAAKRALIKKIEDNKAAVLLGL
                     TYLNRYYGVKFDNFNIKELMLFKPDFYGKNVSVLDRLIEIGSKEDYIKGSRTQESFRE
                     VVAKNTLSGNLHDFLTYNMKLFTNETDINVWFKKAIENNAYVVEQPSTNPAFANKKYR
                     LYEGLNNGQHGRMILSLLNLKDAHLFMISTYNTISFSSFEKYGKDTEEKRESFKSEIN
                     KRAKEQVNYLDFWSRLATDNVRDKLLKSQNVVPTPVWDNHGAPGGWPDRFGHRKDKPD
                     YAPIREFFGRIDKYHDYKYGYGAYAYIFADPQPMDAVYFVMSDLISEYGTSAFTHETT
                     HVNDRMAYLGGHRHRQGTDLEAFAQGMLQTPAEHGHQGEYGALGLNMAFERSNDGNQW
                     YNPDPTKLQTRDQIDHYMKNYNEAMMMLDYAEAEAVLPKVKGDNSKWFKKIDRETRRP
                     MDRNKLSGPHQWDKVRDLIDAEKTTNLETIDDLVNNNFMTIHGNPGNKVFHPEDFGTA
                     YVNVNMMAGIYGGNTSQGAPGSLSFKHNAFRMWGYYGYEHGFIDYVSSKHQGAANKEN
                     NGLLGDDFIIKKVSNNQFSNLEDWKKQWYGEVLTKSKKGFAPIEINGTQISTYEQLKT
                     MFDEAVTKDLTELNDSSIKDKYRNTVVLKSKVFKALLKNTDGFSGDLFTAPQA"
     gene            complement(63666..64229)
                     /locus_tag="VQU30_000302"
     CDS             complement(63666..64229)
                     /locus_tag="VQU30_000302"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014931902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01440 family protein"
                     /protein_id="HET2446484.1"
                     /translation="MNETQIQRETRQVVEDVLEKTNLKQGVLFVLGLSSSEVLGGQIG
                     KESSQEIGELIVETILGILGSRGIHLAVQGCEHVNRALVVERQVAEQFDLEIVSVHPT
                     LHAGGSGQLAAFKFMQDPVEVEFIKAHAGLDIGDTAIGMHVKHVQVPIRPILREIGHA
                     HVTALASRPKLIGGARAHYPQDAIRKS"
     gene            complement(64345..66036)
                     /locus_tag="VQU30_000303"
     CDS             complement(64345..66036)
                     /locus_tag="VQU30_000303"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000831084.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HET2446485.1"
                     /translation="MKRSSLLVRMVISIFLVFLILLALVGTFYYQSSSSAIEATIEGN
                     SQTTISQTSHFIQSYIKKLETTSTGLTQQTDVLAYAENPSQDKVEGIRDLFLTILKSD
                     KDLKTVVLVTKSGQVISTDDSVQMKTSSDMMAEDWYQKAIHQGAMPVLTPARKSDSQW
                     VISVTQELVDAKGANLGVLRLDISYETLEAYLNQLQLGQQGFAFIINENHEFVYHPQH
                     TVYSSSSKMEAMKPYIETGQGYTPGHKSYVSQEKIAGTDWTVLGVSSLEKLDQVRSQL
                     LWTLLGASVTSLLVCLCLVWFSLKRWIAPLKDLRETMLEIASGAQNLRAKEVGAYELR
                     EVTRQFNAMLDQIDQLMVAIRSQEETTRQYQLQALSSQINPHFLYNTLDTIIWMAEFH
                     DSQRVVQVTKSLATYFRLALNQGKDLICLSDEINHVRQYLFIQKQRYGDKLEYEINEN
                     VAFDNLVLPKLVLQPLVENALYHGIKEKEGQGHIKLSVQKQDSGLVIRIEDDGVGFQD
                     AGDSSQSQLKRGGVGLQNVDQRLKLHFGANYQMKIDSRPQKGTKVEIYINRIETS"
     gene            complement(66033..66770)
                     /locus_tag="VQU30_000304"
     CDS             complement(66033..66770)
                     /locus_tag="VQU30_000304"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HET2446486.1"
                     /translation="MTYTILIVEDEYLVRQGLTKLVNVAAYDMEIIGQAENGRQAWEL
                     IQKQVPDIILTDINMPHLNGIQLASLVRETYPQVHLVFLTGYDDFDYALSAVKLGVDD
                     YLLKPFSRQDIEEMLGKIKQKLDKEEKEEQLQDLLTNRFEGNMAQKIQSHLADSQFSL
                     KSLASDLGFSPTYLSSLIKKELGLPFQDYLVRERVKQAKLLLLTTDLKIYEIAEKVGF
                     EDMNYFTQRFKQIAGVTPRQFKKGEDR"
BASE COUNT        20080 a        14555 c        11839 g        20486 t
ORIGIN      
        1 aaaagtcgtg cgctgaacac caacaagacg cttaaatcgt gcatcagtta gttgtttact
       61 tgcttcatca ttcatagaac tactatgcca tattttgttt cgcaggaagt ctgatcattt
      121 caaatccagc cattgctcta ggagctcaag cgacctttat cctattgaat atcttcattg
      181 tatcacgtgg ggttcaaaaa gggattgaaa gagcttcgaa agtcatgatg cccctgctct
      241 ttatcatctt tgtcgtcatc atcgaacgct ctctcagttt gccaaatgcc atggaagggg
      301 ttctttactt cctcaaacca gatttttcaa aactgactag cgctggtctc ctctatgctc
      361 tgagacaatc tttctttgcc ctctcactag gggttacagc catgttgacc tatgcttctt
      421 acttggacaa gaaaaccaat ctggtccagt caagaatctc catcgtagcc atgaatatct
      481 cggtatccat catggcaggt ctagccattt tccaagctcg gtcccccttc agactgaata
      541 ttgaaggggg accgagcttg gtctttatcg tcttgcctca actctttgac aagatgcctt
      601 ttggaaccat tttctatgtc ctcttcctct ttgcgactgt cacttcttct gtcgttatgc
      661 tggaaatcaa tgtagacaat atcaccaatc aggacaacag caagcgtgct aaatggagtg
      721 ttattttagg aattttgacc tttgtctttg gcattccttc agccctatct tacggtgtca
      781 tggcggatgt tcacattttt ggtaaagcct tctttgacgc tatggacttc ttggtttcca
      841 atctcctcat gccatttgga gctctcttcc tttcactttt tacaggctat atctttaaaa
      901 aggctcttgc aatggaggaa ctccatctcg atgaaagagc atggaaacaa ggactgttcc
      961 aagtctggct cttccttctt cgtttcgtca ttccaatcat catcgtggtc ttcatcgccc
     1021 aatttatgta atcaaaagga cttgagtaat gaactcaggt cctttctttt ttatggatga
     1081 ctaacaatta attctaaatc ttgcccttct agagtccaag attcaacatc acttggtagg
     1141 ataaagtgtc tccctttttg gattggatag tttttcccgt caacagttag ttgaccttga
     1201 ccagccaaga cactcaacaa gctgtagtca gctgtctttt caaagttaac ttttccagta
     1261 atttcccatt tgtaaactgc gaagaaatca ttggatacaa ggatagtgga acgtagatca
     1321 tctgctttga ttgtcactgg acggctattt gcgggttcac caatgttcaa gacatcgata
     1381 gatttttcaa ggtgaagttc acgtaaattg cccttgtcat ccttacggtc aaagtcatag
     1441 acacggtaag tggtatcgct agactgctgg gtttcaagaa tcaagatacc cgccccgata
     1501 gcgtgcatgg taccgcttgg tacatagaag aaatctcctg ctttaactgg cacttttgtc
     1561 aacagcgcat cccagttctt atcctcgatt tgctggcgga gttcttcttt tgacttggca
     1621 ttgtgaccgt agataatctc tgaaccttca tctgctgcaa tgatgtacca acattctgtt
     1681 tttccaagtt cgccttcatg ctcgagtcca taagcatcgt ctgggtgaac ttggacactg
     1741 agccagtcgt tggcatcgag gatcttggtc aaaagtggaa atacaggttc tggacgattg
     1801 ccaaataatt cacggtgttc cgcatacaaa gtagcaagat ctgttccctc gtaacgacca
     1861 ttggcaactt tagaaacacc atttagatga gctgagatag cccagtactc tccgactttt
     1921 tcacttggga tgtcgtagcc aaactcatca cgtagcttgg taccacccca gattttttct
     1981 tgcataactg attgtaaaaa taatggttct gacatcttaa tctcctgtct gatttttctc
     2041 ccctcattat agcaaaaaaa gagttccatt tgaactcttt tttacatctt ataaagcagg
     2101 gagaagattt tataaaaata gtaaacaaat gtgctctact cgatgcttac accattgcta
     2161 taaatgacat gtaccaatag aaggacttct tcttgctacg tttgagagtc ccatttccta
     2221 cattatctcg atctacatag ataaagccat agcgcttatt catttcccct gtgccagctg
     2281 aaaccgaatc gatacagccc catgtcgtat aaccaagcaa gtcaaccccg tctttgtaaa
     2341 tggcatctcg catggccttg atgtgggcct ctaagtaagt aatccgatag tcatctgcta
     2401 cataaccatt ctcatccggt gtatccatag caccgagtcc attttctacg ataatactat
     2461 actaaaatca aaaagcatta tataatagtg atatgaaatc aactaaagaa gaaatccaaa
     2521 ccatcaaaac actttttaaa gactctcgta cagctaaata tcataaatgc cttcaaatca
     2581 ttctatttcg tctgatgggc aaatcttata aagactccga ctaatattgg ttttgcattt
     2641 attcctccat acacaccaga gatgaaccca tcgaacaagt gtggaaagag attcataaac
     2701 gtggatttaa gaataaagcc tttcgaactt tggaagatgt catacaagga ctggagaagg
     2761 aggtgataaa gtccatcgtt aatcggagat ggaatagaat gctttttgaa agcagatgag
     2821 tattatatgc aatttcttta tataaaaaga ccggattgct ccgatctttc aatagttcat
     2881 attctcaatt tctattttaa aaatagctaa ggttaacgtc aaatgactac gcgacctatt
     2941 tcatacgata aaaatcaagc actagaccag caggtccttg aactaataag gactctgttc
     3001 cccaatcggt tacagttggt ccgtgtaaaa cctttatacc aagctcattc aaccgtttgt
     3061 agttctggtc tacatcctca acctcgatat gaataatgat tcctgactga aagttttcca
     3121 aaggaaccaa atgattttgt gacaacataa ggcagtgact accaatcgta aactgagcaa
     3181 aaccatcatc agcataatct gcctttttat ccaaaatatg ctccaagtca gcacagactt
     3241 ggggaacatt tgaaacgata atatctaatt gatttaaatt catttactct cctccataaa
     3301 aagaccgaat tgctccgatc ttttaaagtt ctgctctatg aaaatcaaag aataaagtct
     3361 acaagtttca tatttgattt tcggcgagag gaattattta attgcgcgtg attgcaatcc
     3421 ttcttcttcc aagaagagac ggaatggtac gagttcttct gcttcgtatt tttccttgaa
     3481 ggctttgata gcttcttctg agtgaagttt tggatccaat tcaagtactt ctactggaag
     3541 tggacggtgt tgagtgatgc gagcatcgat gacaacagtt ttaccttctt tgttcaattt
     3601 aacagcttct gcaacaactg catcgatgtc ttcgatacgg tcaactgtga atccaacagc
     3661 tccttgagct tccgcaattt tagcgtagtc agcgtttgtg aagtctacac caaacaagtg
     3721 tttgtttgta tcttcgtatt tgttcttgat gaagccgtac tcagcatttg agaagacaag
     3781 gttgataact ggaaggtcgt attgaacgtt tgtgataacg tctgggtagc acatgttgaa
     3841 tgctccatca cccatgatgt tccatacttg gcgatctgga ttgtctttct tagcagcgat
     3901 accaccagga agggcaatac ccattgtcgc aaagagcgga gatgtacgcc acatattctt
     3961 aggtgtcatg tgaaggtgac gagtagatgt ttgagtagtg ttacctacgt cgattgagta
     4021 gatagcgtct tgatcagcat gtttgttgat tgcattgtaa acttgataca attgcaattc
     4081 accctcagtt ttaccttcga gtttgttcat gtaatcacgc cagttttggt tgttcttaac
     4141 gtttgcacgc caccatggag ttgattcaac tgggtttact ttgtcaagga tagctttagc
     4201 tgcttgacca gcatcaccaa ggattgaagc gtcaagggca tgacgtttac caagtttgta
     4261 agggtcgata tcgacttgga tgaatttttc agtgttcttg aatgcttcgt aaacttcagc
     4321 aaatgggaag tttgaaccaa ggaaaagaac tgtgtctgct tcaaagacca cttcgttggc
     4381 tggtttccaa ccaacacggt aagcagaacc tgtcaaacct tcatagttcc attcgaaagc
     4441 ttcaaagttt ttaccagttg tgatgattgg tgctttgatt ttacgtgaca attcagtaat
     4501 cacttcacca gctttaacac caccaaatcc agcatagata actgggcgtt cagcattgtt
     4561 caagatttca acagctttgt cgatttcaac ttcgttcaaa gcaggagcga tgaatgagcg
     4621 ttcgtatgaa cctgaaccgt agtatgagtt ttcgtcgatt tcttggaaac cgaagtttac
     4681 tggaatttca acaacagctg gacctttttt agaaattgca gcacggcagg cttcgtcaat
     4741 tacttttggc aattgctcag cgtaagctac acgtttgttg taaacagcga taccgttgta
     4801 cattgggttt tggttaagct cttggaaagc atccatgttc aattcgttaa ctggacgtga
     4861 tccaaggatc gctaggaatg gagtgttatc catagctgca tcgtaaacac cgttaatcaa
     4921 gtgagtcgca cctggaccac ctgaaccaac tgcaaccccg attgagccgc cgaatttagc
     4981 ttgcataacc gctgcaagag cacctgtctc ttcgtggcga acttgtaaga agcggatatc
     5041 tttgtcttca gccaaagcgt ccatcaatga gctgagtgtt cctgatggga taccgtagat
     5101 tgtatctacg ccccatgttt tcaatacgtt aagcattgct gcagatgcag taattttccc
     5161 ttgagtcata atgataactc tccttcaatt tttttagatt tggagaatac gattacatag
     5221 aattggaaac gttctccaaa tttttactat tccactgtat catatttatg ctgacttttc
     5281 taaaaatctg ctcaaaactc tctattctct attctaatac agttttgaaa gttctgtcat
     5341 ttctgtttta taacaaagaa atctagtcat tacttttagt ctattttact aaaatttaac
     5401 agaagggaac tggtcagaac agatacagaa ctaaaggcca tggctagacc tgccaattct
     5461 gggttgagag ccagtccaac acctgaaaag actcctgctg caatcggaat tccgacaaca
     5521 ttgtagataa aagcccagaa aagattgagt agaattcgat gaaaggtttt cttactcata
     5581 tcaaaggcac gaaccactcc taaaagatta ttggttgtca acaccaaatc tgctgactcg
     5641 atggcgatat ctgttccagc tcccatagca atccccacat ctgctacact aagggcagga
     5701 gcgtcattga taccgtcccc aacaaaggct actttccctg actgttgcag tttatggatt
     5761 tcatgggctt tttcttctgg caagacgcct gcaatgacct cttcaattcc gatttgatct
     5821 gcaatagcac gcgccacacc agcattgtct cctgtcagca tgactgttcg gagaccacgt
     5881 ttttttagct gactgatggc tagcttagca ttttccttag gaatatcttg caaagcaagc
     5941 aagcctttga tttcattgtc aacagctaag aacacaactg tcttagcttc tttttctagt
     6001 tcttctagtt tatcttgata agtattagaa atatccatac catccagcat tttagcattt
     6061 ccaagtaaaa cttgttttcc attgattcgc cctgaaacac ctttcccgtg caaggactga
     6121 aaattttcaa cagtttgaaa ctcaagtcca gcttcactcg ctcgcttaac gatagcctca
     6181 gccagtgggt gttgagaagc atcttccaag gaggctgcca atccaaacac ttctacttcg
     6241 tcgccgatga tatctgttac cacaggtttc ccttccgtca aagtcccggt cttatcaaag
     6301 acaagagttt gaactttctg gatttcctgt aagacagttc catttttgag gagaaccccc
     6361 atcttggcac tacgtcctgt ccccaccata agggctgtcg gtgttgcaag tcccaaggca
     6421 caaggacagg cgataatcaa aaccgccact ccgtagagaa gagaggacac aaagctagct
     6481 ccaagcacga ccacactatc cctgagcaag acgaaccaaa cccaaaaggt catgattcct
     6541 aaaatgacaa ctactgggac aaaaatccct gaaatcttat ccgtcaagtc ctgaatcggc
     6601 gcacgacttg tctgagcttt cttcacaaaa tccacaatct gagccaaaac agtctctgag
     6661 ccaacttttt ctgctctaaa gacaagcgtt ccactatgat tgatggttga gccaatgaca
     6721 gtatctccaa ctgtcttgtc cacaggcaga ctctcacctg tcaccatgga ttcgtcaata
     6781 ctagagacac cttctactac gacaccatca acagcaatct tttcaccggg acgcactcga
     6841 atcaggtcgc ctaccttgac ttgttccaaa ggaacttgga cataactatc atcactcaag
     6901 acttctgcgg ttttagcttg caagtccagt aatttctcca cagcttggga cgtatttttt
     6961 ctcatttttt cctcaaaaac tgctcccaaa agaacgaaaa agaggataaa tccagcactt
     7021 tcgaagtaaa cagggagacc agcaaagaga gcaactaggc tatagaaata agccactaga
     7081 gttcccagcg caaccaaggt atccatgttg gcattgtgct ttttaaaact ggcccaagca
     7141 ctctggatat atggcttacc tgcaactaac ataataggcg ttgttgctag aaaggttccc
     7201 caatgcatga cttgatgact aatgctacct gtcaacatcc caatcatgag aatcacaaga
     7261 ggcacagtaa agatactagt aatccaaaaa cgttgcagga gagatagaga ttttcgagtc
     7321 ttctcaacga ctatatagct tcccttttgc atcttcatgc cacaagaaaa ttcatgtcgc
     7381 cctaattctt gaggtgtaaa acgaatgact ttctcctcat ctacgccgat tggttccaag
     7441 ataccttctt cttcaaacag aatttcctta taacagtttg aaggagtagc acgatgaaag
     7501 gtaatctcag ctggaattcc cttttgaagc tggatatggg ctggatgata gcctttttca
     7561 gctcggatac ggattttttg aatgccattt tctaagcttg ctttcacaat ttctgtcata
     7621 gtctccacct actctacaat catcttgccg tgcatcatgt tcataccaca agcaaagcca
     7681 aactctccaa cctgctcagg cgtgatttcc actacatact cttcccccat tggcaggttc
     7741 gcatgtacac caaaatctgg aaaaacaatt tgatccagac atggtgaagg atccttgcgg
     7801 tcaaagacaa tgcgtgctgg cactgatttc ttgaggacaa tcaactcagg agtatagcct
     7861 cccatgactt ccactcgaat ctcttggtat ccgttttttt gctgggcttt ttgtccagat
     7921 ttttcaggct ttttgaaaaa ccaaaacaag ataaacgcga taagggcaat acaaataatg
     7981 gttacaatac tatttaacat gacgtctcct ttacatacaa ttacatctta cttctgttac
     8041 agcacttgat ttcttctctg aaatcacagc ttccaagtct tccaagtcag tctgagtaaa
     8101 ttcacattct acaatcaagt cagccaacaa attcctaatc ctacgggaac aaaccttgtc
     8161 tttgatatct tggacaagta aatcccgact ttggtctaga gttaaaaggg ctgaataaac
     8221 aaaggacttg ccttcttttt tccgagtcag acactctttc tcaaccaaac gagccaaaag
     8281 agtttgaatg gtcgacttgg accagtcgaa ccgctctgcc aaaaccctaa tcaaatctgt
     8341 actggtctgc tccccctgca tccaaataat cttcatgacc tgccattctg catctgaaat
     8401 ctgcattacc atacctccaa aatctacatt tgtcaattac actcatcagt atactcttaa
     8461 aatctacatt tgtcaattat agaaataata ttttcttcga aaaatagaat tttaatcatt
     8521 tgaaaaacga tttgcagtca aatattacta tataaacaat aaaaatatgc tatactaaag
     8581 aaaaaagaaa acaaccacta ggggtgcgta aagctgagat taacgactgt tagatccctc
     8641 tgactcaatc taggtaatgc tagctgatgg aagtggaaat gataatgggg actagcagtc
     8701 ttctattgcc tttctaaaac agactagctt gttcttaaga atacaaactt cagttggttg
     8761 ggaggtttta gatgacttat ttacccgttg ctttgaccat tgcagggact gaccctagtg
     8821 gtggtgctgg cattatggca gatttaaagt cattccaagc gagagatgtc tatggaatgg
     8881 ctgttgtaac cagtcttgtc gctcaaaata ccagaggtgt tcagctaatc gagcacgttt
     8941 ctcctcaaat gttgaaagcc caattggaga gtgtcttttc tgatattcca cctcaggctg
     9001 taaaaactgg aatgttggct actactgaaa tcatggaaat catccaaccc tatcttaaaa
     9061 aactggattg tccctatgtc cttgatcctg ttatggttgc tacaagtgga gatgccttga
     9121 ttgactcaag tgctagagac tatctcaaaa caaacttact acctctagca actattatta
     9181 cgccaaatct tcctgaagca gaagagattg ttggtttttc aatccatgac cccgaaggca
     9241 tgcagcgtgc tggtcgcctg attttaaaag aatttggtcc tcagtctgtg gttatcaaag
     9301 gcggacatct caaaggtggt gctaaagatt tcctctttac caagaatgaa caatttgtct
     9361 gggaaagccc acgaattcaa acctgtcaca cccatggtac tggatgtacc tttgctgcag
     9421 tgattactgc tgaactagcc aagggcaaga gtctttacca ggcagttgat aaggccaagg
     9481 cctttatcac aaaagctatt caagatgccc ctcaactcgg tcatggttct ggtccagtca
     9541 accatacaac ttttaaagat taagaaaaaa actctctagt tcccacttta agggaattag
     9601 agagttttta tactcttcga aaatctcttc aaattacgtc agcttccatc tgcaacctca
     9661 aaacactgtt ttgagctgac ttcgtcagtc ttatctaaaa cctcaaggca gtactttgag
     9721 caacctgcga ctagctttct agtttactct ttgattttca ttgagtatta attaggaaag
     9781 aatgtcatgc aactttgtta aaaaggcttg cgtttttgcc tcaatatctt ctgcttgcat
     9841 caaatcacgt acaacagcta caccagctat gccagtgccc ataagctgat caatattctc
     9901 cgaagtcaag cctccaatag caactactgg aatggcaacc gtttggcaaa ttgttttcaa
     9961 ggtcgatatc agagtaatgg gcgcattttc cttggtggtg gttgggaaaa tggctcctgt
    10021 acccaagtaa tctgcacctg atttctccgc ttccagagct cttttaaccg ttttagcggt
    10081 gacaccgagg attttttcag gacccaagac tttgcgagct accgaaactg gtaattcatc
    10141 atctccgata tgcagacctg ctgcatcaac cgcaagacaa acatccaacc gatcatcgat
    10201 tatcaagggg acctgatagg catctgttat ttccttgact tgttttgcca gttgataata
    10261 ttgattggtt gtgagatttt tttctcgcaa ttggactatg gtaacccctg aacggcaggc
    10321 cgtctcaact tttgcaagaa agctttccac ggaatcttga tagcgattgg ttaccagata
    10381 tagtctaagt gcttctctat tcataaacct ctcctttgat ggtatctagc caattttcat
    10441 ctcttcttag gagcgaaagc tgattgagta cttggtaacg aaattcttcc aatcccattc
    10501 cttgaacaac tattttctca gcagcgatat tgagataaga gactgctaag caagaagctt
    10561 caaaaccagt ctttccttgg ctgagaaaaa cggctgttaa ggctccaacc aagtctcctg
    10621 tccctgttat ccagtctaat tcagtacagc cattctccag tacagcaact tgattctccg
    10681 aaacaataag gtccttgggg ccagtaacta agaaagacat accaggatag gtctgacacc
    10741 agtctttcaa gacttgaagc aaatcctccg tttcttgatc tttagcactc gcatcgaccc
    10801 caacgccgtg gtgctttaat ccaacaagac ttcgaatttc tgacatgttt cctttaagga
    10861 ccgtaggtct atagtctaaa aggtctttaa ctaagctctt acgaatggat gaagtcgtta
    10921 cgccaaccgc atctactacc atcgggagag aagattggtt tgcatacgaa gctgccatgc
    10981 ggattgcttt ttccttctca gctgacaaat gccccaaatt gatgaagaga gcctgacttt
    11041 gcttagtaaa atcaagaact tcacggggat catctgccat gacaggtttg catcccagag
    11101 ccaaaatccc atttgccagc atctcacaag aaatctcatt ggtcatacag tgaatgaggg
    11161 aactagagcc tataggaaaa ggatttgtca atgcctgcat cagtctatcc tttcagcaaa
    11221 gaaatatcct tgcacttttt taaagaattc ctgcttgatt aaaaatctaa atgcaataaa
    11281 ggaaatcgct gtaccaatca aggttgctcc gaaaaatcga ggagtgtaga taaaccaact
    11341 aagcttagca gccgatcctg taaagagcac cataacagga taggaaacaa tagaaccaat
    11401 aatacctgtt cccacaattt ctcccaaggc agaaaagtaa aattttcgac cgtacttata
    11461 aaagagacct gctagaaggg ctccaaaagt cgctcctgtg agagctaaag gcggaatccc
    11521 ttgagtcgtc atacggataa aggctgtcac tgtagccata gccaaggcat aaacaggtcc
    11581 catcatgatt cccgctagaa tattgactac actggacatc ggtgccattc cctcaatccg
    11641 aaagataggt gtaaggacta catcaagggc aatcatcata gataaaatgg tcaatttgtg
    11701 aacttgtagt tggtgctttc tcatgtttct attcttctcc tttttctaaa gactgtaaat
    11761 cgctcttcca tgtctggtgt tggtaagcca tctcccaaaa cttggcttcc atatgaacac
    11821 tgatgtggaa ggcatctagc attttttgct tatctgtctc atcactttct cgataaagct
    11881 gattgaccag tgctccctcc tctctgatct gttgctctaa ctcatccgta atataagttt
    11941 caatccattg ttgatagaga ggatttggtg atggtttaag attaagtgat ttgcctatat
    12001 catggtataa ccaaggacaa ggaagcaagc ttgcaaaagc tatggctaag ttcggttctg
    12061 caaattgcct ataaatatga gaaatgtaat gataacaggt tggagcgatt ggatgttgct
    12121 ccatttcctg gtcgttgatt tccaattcct tgaaaaattg ttggcgaata aataactcac
    12181 cctccactaa accctgagca ttttgtttca agagtctttt catctcttgg tttgaagtct
    12241 tatcagccaa aagatgatag atttctgaga aagccttcag atagtaggca tcctgaatca
    12301 ggtaatagcg gaaaatggca ggttctaaat tcccctcttg taattgtaaa ataaagggat
    12361 gatgaaagga agcctgccaa gctttcttgg ataattccat cgcaatatct gtaaattcca
    12421 taataactcc tttataaaaa tagactggtt tgaagcaata aaaagaaaag caggtagatt
    12481 aattttgttt ttttaggaat ataaaaagtc cgatagctat tcttcaactg tgcatgttcg
    12541 tcatatccgt aagcagatag agctctcagg taaagatggc gccacctaaa gactgtcatc
    12601 agaaccttac tgtaaatcaa gggcgaccaa aaatgtagtt tttgaccacg taataggcaa
    12661 gcttctttga gggacttgat ttcttgctga atgagaggaa aagaattgaa taccacaatc
    12721 aaggcatagg accaagagcg tgatagcccc ttttgagcca agtacaagag aagctctttt
    12781 agtgaaatag aggaaacaaa gacaaggccg atacaaactg tcacaaaggc cctcgttcca
    12841 agcatgactg cctgtgaagc atctccgtgt aactgaactg cccagtagtt ggcaaaagat
    12901 gggaaaatgg caagtatgat catccaagct aacattttaa atcgacggta atagagcata
    12961 aagagaatac aaaatgcgac taccgaaaga ttcagagcaa tcgaaggaat gaaagatgtt
    13021 tccaaggata aaatcagcaa gaagagactg ataatcggtg tctgggttgc tactttgacc
    13081 atactatctc acctcccctt gggtattgct actctgagat gtaagtggtt tggtaatggt
    13141 cacttctttc acatgccgaa gaccctgact agtcatctca atccaataat caaccacaga
    13201 aatcaaaggg tctaaacgat gactaatgag cagaaaactt cttccttgat tcctctcctc
    13261 cacaatccac ttgcaaaaat aatggcaggc tctatcatcc aaacctgcaa aaggttcatc
    13321 tagcaagatc acggaagcct tactggtcaa gatggtcagg agctgaagaa ttttttgctg
    13381 accaccactt aattgatagg gactcttatc gactgcctgc tccaaatcaa aatatcgtaa
    13441 agcttgaaaa atccgctgat ttctttcaga atcaggtcca tctaattgaa gctcctctcg
    13501 cagactgact cggataaact gcttctcagc ttcctgaaca acaccagtca gatcacgata
    13561 caaactcttt ttctttttca ggaccgaacc cttccaagta atgctcccct tatacttttg
    13621 aaattgaaga atagaccgaa agagggttga tttcccgaca ccattgtcac ccaggataca
    13681 ggaaatccct tgatagaatg tgaaatcagc aattgaaaag agggggcgat taccaagctc
    13741 accagtcaca cggttcatat ggaatagttc cgggctagaa gcaacttcct ttgaagcaac
    13801 ctgtgtcatc tcataggaag ggatttgaaa cacttccctt agttttccgt ctcttagctc
    13861 caccatatgg tcgatatagg ctttatagtc agataaatca tggtcgcaca aaataactgt
    13921 cttcccatca tagaccaact cttttagaat ctccaatatc tcgattctgc tcttgcggtc
    13981 aatggaagcg aagggctcat ccaagagata gaccctagga ttcatggcaa agaggacagc
    14041 cagcgctgct ttttgctttt ccccacctga taagtgatgg atgagacggt gcaagatgtc
    14101 cttgcaacga cattgctgga caacctctgc tattttagaa tcaatttcct gaaggtgata
    14161 gccgatattt tccatggtaa aaaccaactc ctcaaacaag ctctccatgg taaattgatg
    14221 attaggattt tgcaagagaa taccaaccgt ctggacacgt tcgacgatag aaagctgact
    14281 gacctcgctc ccatctatca ggacttgacc gctataggga agagaactaa cttgggcaat
    14341 catttgaaag aggctggatt ttccagaccc actactccca actaacaagg taaaggcttg
    14401 cgcatgaaaa gtaaaatcaa acggctcaga gaagattggg gactgaatcg ctcgtagttc
    14461 cagacccatc tatgcttttc ctccagttgc aaactgatga tagagtttga caatggcacg
    14521 aaccaagatg gtacagaaga aataaacaga aataaaacgt accacaagca aggaaaggac
    14581 aaacggaagg gaaaaggcgt agtaacctaa cttaatgtat tcatagacaa agctaacaag
    14641 cgtaatccca atactattag cagttagaga gagccaactt tcatagcgat tcttagttac
    14701 gataaaacca aattcacttc ccaaaccttg aacaaagcca gacaaaagag ctcctagacc
    14761 aaattggcta ccataaagga cttcagcaag cgcagctagc acttctccaa tcgttgcact
    14821 tccgactctc ggaacaaaga tggcagcaat gggcgcagcc atacaccaga gaccgaagag
    14881 gatttcattg gcaaaggcct gcaaaccaag aggtgttaag agtagactga gaatattata
    14941 cacatatcct gaaccaacga aaaccccacc aaaaaagata gacaagaaag caagcaagat
    15001 aacatctttt aactgccatt ttttcaacat aaaaaactcc tttttttaaa gaaaagtggg
    15061 gcactcaaga agaccgacct aaatactttg tatagcagac tgaatttaga acagtacaca
    15121 agaacactaa aatatttcta gaaattaatt tgaattttct aattgatttg ttcgcatctt
    15181 atttcaatct actatatcat cttcatccag tttcgtaaaa gaaaaaactc taattacaga
    15241 tacaaattag agttcagctt acaagattag acagttcttt tcgacatacg aaaaaaacat
    15301 ttcacatttc ccttcgccag tcttaactgt atcaggttca atgggtatca tctcagccta
    15361 aagcacccca aatgtcttta ttatttaatt atgtgattat tataacacac attttatact
    15421 agttcaagaa attgaactgg aaatacagcc ttgcactcac aaagacagca gatctttctt
    15481 ttgcaaaaaa caaatgacct gtttgatgaa ttagccattc aagctgaatc tggacatagc
    15541 tttttaaaaa aggaaaatcc tacttactta gaatccaagg atagatatct attgttcact
    15601 catttcccga acagtttttt ctatattttt tgcatacgat attgccgaaa tgattgaaac
    15661 gccatccata ttggtcttta taatgtcttt aatatgtttc gtctgtatcc caccaattgc
    15721 aactaaaggc atttgtggca atagttttct catcaattca agaccttcat aacctatagt
    15781 accaccagca tcatcctttg actgggtacc aaatacaggc ccaacaccta cataatctac
    15841 atattcaact tttgattgtt gaaattcttc ttcgtttctt atagaaagac caattatttt
    15901 atctggcatc aattttctaa tttcatcaac accaatatca tcttgaccta catgtacgcc
    15961 atcggcgtca atttccattg ctaaatctat atcgtcatta acgataaatg gaacattgta
    16021 ttttttacaa agttctttaa tttggatagc tagctcaagt ttttctaagc cttctaaagc
    16081 accctcacct ttttctcgaa attgaaataa ggttatacca ccttttaagg cttcctcaac
    16141 gactgtatat agattttttc cttggcaagt agtcgttcca caaataaaat atagttttag
    16201 taattcttta tgaaacatct tacttcactc ttttgaattc ctttacatct tcatctgtaa
    16261 tctcgtataa ggcatttata aattcaactt taaatgtccc aggaagatgt ccatttggac
    16321 gtttttctgc catttctcca gcgatattgt aaaccaacat tgctgtttct aatgatttca
    16381 attcttgacc tttttctagt ccgataaagc ttgctactac agctcctaat aagcatcctg
    16441 tcccaatgac tttcggcatc atagcactac cattatgaat cattaccact tctccattaa
    16501 cagcaatggc atccacttca cctgttacta ctattggaat attgaacttc tcatttgctg
    16561 ctagagcaat ttcgtcaata ttatctacgc ccgcactatc tactccttta gatgccacat
    16621 ctattcctac taaagaggca atctcgccag catttcctct aatcgctgct agtttataat
    16681 tgttgattag atcatctgct actttttttc tatattctcc tgctccacag gctacaggat
    16741 ctaaaactgc tgggacatta tatttctctg caattttcag agcagcttgg tataatttcc
    16801 aattttcatc tgtcaatgtt cctatgttta ttaataaacc accagcatac tttaacaaat
    16861 cctctaaatc tgctggaaac tcactcatgg ctggtgaggc gcccagtgct actaatccat
    16921 ttgctgtgaa attttttact acatcattgg ttatacaaat gaccaatggt gctttttctt
    16981 ttaataattt taaacttgtc atattgaaat ccttcctttt cactttatac gatctactga
    17041 tttcgattta tttctatctt tcgttaagaa tttttttcat ttacattgaa tgatttatac
    17101 tcaatgaaaa tcaaagagca aactaggagg ctaaccgcag gttgctcaaa acactgtttt
    17161 gaggttgtgg atagaactga cgtggtttga agagattttc gaagagtctt acctcatcaa
    17221 atttgtaaat atcatgagcc ttctctagac atcgtaacca atatcaaaaa aagctaattc
    17281 taaagcgact gcttgattcc agcgttgctg aagttctgtc aaatcttctc gatttttatc
    17341 gacacgattg agttcgtcaa ccagaaattg aacccactct gcaaagaaag gacctctgtg
    17401 gagattgatc cattccgaat gaatatagac ttcaggtaaa gccaaatctt tagaacccca
    17461 gtctaaatag agaccttctg caatgaccag catgaccaaa agatgggcat agtctgatga
    17521 agccaccgcc gaatacatta gatcctgaaa ggcttttgtt acagggtgca aagtcacttc
    17581 tagatagtca ttctctgcta cttttaactc tttaaaagcc ttttggaaat aaccatcttc
    17641 atctgcttca agaaagccta gttgcttggc aaaacgaagc ttggattcaa gtttatctgc
    17701 gtgagctacg caggcaccca gcatggataa gaaggcatca aagaagtgat aatcttgaat
    17761 cagatagtcc tttaagacct tattctcaat tgtccccgca aaaagttcct taacaaaacg
    17821 atgattgatt gcagcctgcc aatccttctg actgcttttt aataattctc caacagtcaa
    17881 acctggctga aatgcatagt cttgtgtttc catatttact tctcctctct ttacttgtta
    17941 gtaattaata aaacaccaag aaatatcaag caaaatcgta attccacttg atccttttaa
    18001 agcacatcga gagcatttgc agagagctaa ctaaacaagc ctatccagtt tatataaaca
    18061 aaaaactcca attacaatca agaattagag ttgacttaca agattagatc gttcatttcg
    18121 ccatacgaaa aaacgtttca catttccctt cgccagtctt aactgtatca ggttcaatgg
    18181 gtattatctc agcctaaagc accccaaatg tctctattat ttaattactg aaccagtata
    18241 gcaaaaaatg aaagccctag caagatattt gaccgaaaaa tatctttata tataatatat
    18301 tgaaactaga atagtacacc tctacttcta aaacattgtt agaaatcgat ttgactgtcc
    18361 tgattgattt gtcctattct tatttcattt tactatagtt ttcgatagca atttattctt
    18421 ccaatacacg aagaaaaacc tccacattca gtggaggcaa tctgttttat caatacaatt
    18481 ttaagtcacg agggtcaact gggaaggttg ggttgtatgg attgtgacgg agcttaaagt
    18541 gtttgacatc ttcaatggtc tgagctccag acaattgcat aactgtcttc aattccgcat
    18601 tcaagtgttc aaagacttga cgcacaccga cactaccacc gagagccaag ccataaataa
    18661 cagggcgacc aatagctacc aagtctgctc ctgaagccaa ggctttaaag acgtgttgac
    18721 cacgacgaac accagagtca aagacaatcg gcacacgtct atcaactgct tctgccactt
    18781 cttgaagcga gtcaaaggca gctggtccac cgtcgatttg acgaccaccg tggttggtta
    18841 cccagatacc agaagctcct gcagcaagtg aacgttcaac gtcctcacgg cattgtggtc
    18901 ccttgacata cacaggaaga ccagagtatt cagcgataaa ttctacatcg cgtggagaca
    18961 agcgttgttt agctgatttg taaacaaagt ccattgattt accagcacct tctggcaggt
    19021 attcttcaac aatcggcatg ccaactggga agacaaaacc attacgctta tccacttcac
    19081 gattcccccc tacagtagca tctgccgtca agacaatcgc tttataacct tcagccttca
    19141 cacggtccat gatgtggcgg ttgataccgt catccttact aaagtaaaat tggaaccaat
    19201 ggggtgtccc ttgaagggct tcagaaatct ctggaaggtc aacagtagag taagagctgg
    19261 ttgtataaag agaaccaaac tcatgcacac cacgcgcagt cgccacttcc ccctgttcat
    19321 ttgccaattt atgagccgca acaggcgcca taatgattgg tgaagatagt ttttcacctg
    19381 caaattcaat ctctgtactt ggattttcaa catcgcaaag tgtatgagga acgatgagtt
    19441 tgtggttaaa ggcgcggata ttctctctta aagtgaaagt atcttccgcc ccactagcga
    19501 tatagccaaa tgctgcttta ggaataactt gttgcgccat tggctccaaa tcataggtat
    19561 tgatgaagtc tacatgacct tctgcattgc ttgttttgta tgacataaaa tgccctcctt
    19621 gattaagtaa gcgtttgctt tttactacac aactataata actctttttt caatcatttt
    19681 caagagtttt gcttaaaaac catcttattt tttcatacaa tatactagcc ctactttcct
    19741 taaactctaa actttagtct atattaagtg aatcgttgag attttttgct gccaggcatt
    19801 tgaactactt ttttatttgc ggattctatc tactaatact ataaaaaaac aagtgaataa
    19861 gacaccagaa catcctctaa taggacctat ggacttatat cagtcccata tatactgttt
    19921 aagcaagata ctatcctagt tgacgctaac ttcctatccc acttattaat tttttattta
    19981 tagtgaatct gaacaaatca attggggaat ccaagtcaat ttctagtact ttttgaacag
    20041 tttcagcgta ctatcgtaaa atgaaataaa acatgcacaa attgcttagg gaatttaaac
    20101 caatttctaa caatgtctta gaaatcaaag tgtactattt caacttcaat atactacact
    20161 tcattttctc cttaaattca gtctcttttt gaatcaaaaa atcccctggt aagagccaga
    20221 ggataagaat ttatttcatt gttgggaaga gcaatacatc acggatagtt gttgtatcag
    20281 tgaggagcat gcagagacgg tcgataccga ttcccaaacc acctgttggt ggcataccgt
    20341 attcaagagc ttcaatgtag tcatagtcga tgcctgtcgc ttcatcatca ccaagttctt
    20401 tggctttagc ttgggcttca aaacggctaa gttggtcgat tgggtcgttc aactcagtaa
    20461 aggcattacc gtactcctta gtcatgataa agagctcgaa acggtcagta aagcgttggt
    20521 cttcaggatt tttcttagcg agtggagata cagctactgg atgtccatag acaaaggttg
    20581 gttggattaa agtttcttca acaaactctt caaagaaggc attgatgatg tgaccaacct
    20641 cagtgtagtg tttctcaact ggaactttct tctcagcagc gatagtttta gcttcttcca
    20701 aagtcatgtc ttgccagaaa tcgacaccag taatttctct gatagcatcc accatatgaa
    20761 cacgcttaaa tggttcgtta atcttgattt cagtaccttg gtagttgact gggccatcac
    20821 ctttgactga tttagcagcg tgttggataa tgccttcagt caagtccatg atgtcttgga
    20881 agtctgcata agcttggtaa acttcgatag aagtgaactc agggttatga gtagcgtcca
    20941 ttccttcgtt acggaagata cggccaattt catagacacg ttccatacca cccacgataa
    21001 ggcgtttcaa gtgaagctca gtcgcgatac gaagcaccat gtcaatgttt tgggcattgt
    21061 ggtgggtgat aaatggacgg gcagcagcac caccggcttc attatgaaga acaggtgttt
    21121 ccacttcaag gaatcctttt tggtcaaggt aacgacggat ttcagagatg atttttgaac
    21181 gagtgacaaa gcgttcaaag ctttcacgat tagaaatcaa gtcaaggtaa cgtttacggt
    21241 aaattgtttc aacgtctgtc aaaccatgga atttctcagg aagaggacga agagccttag
    21301 acaagtgtgt gatgtgggtt gccttgatag agagttctcc catatccgta cgcatcactt
    21361 caccttcgac accaaggaag tcaccaaggt ctgctttttt gaagatttcg tagttttctt
    21421 caccgacagc atccttacga acgtagatct gaatctggcc ttcgcggtct tgaaggtggg
    21481 caaaaccaac ttttccttta ccacgtttgg ttatcaagcg tcctgcgata gtagctgttt
    21541 cgtttttatc gtgtaattgt tctttatcga ggttggcata tttatctttt aattcttgtg
    21601 aatttgcagt acgttcaaaa cgttttccga aaggatcgat tccttgttcg cggagcgcag
    21661 ccattttttc acggcgaacg atctgctggt catttagttc ttccatatgt tctgtagaca
    21721 tgggatcctc ctagttttac tcaaaattga atacgatgag tcattttttg cgatactccc
    21781 attttatcat aaataagcaa gaaattcacg gataatcttt aaaaactaaa aagaacctga
    21841 cgctaaaatc actggaaaga agtgaaagta tctcccgccc cactagcgat atagccaaat
    21901 gctgctttag gaataacttg ttgcgccatt ggctccaaat cataggtatt gatgaaatct
    21961 acatgacctt ctgcattgct tgttttgtat gacataaaat gtcctcctta ataagtaagc
    22021 gtttactttg tgtattacaa aaatatctta actctttttc aaaactttta aaatattttg
    22081 tttggaaatt tcagaaattt tatgtctatg ataaaaatcc ttataacggc aataaaaaat
    22141 agatattatc caaagaagat tttaagtgct acaataactg tattatttct agatgggagg
    22201 ttctattttt ggattgatcc attgttgaac aatatctacc actatatcaa aaggcattct
    22261 ttctgacctt gcatattgca gtttggggaa ttttgggatc ctttctgctc ggtttaatcg
    22321 ttagtatcat ccgacattat cgaatccttg ttttggcgca agtagcgaca gcctacattg
    22381 aattgtcacg taatacgccc cttttgattc aactcttctt tctctacttc ggtcttcccc
    22441 gaatcgggat tgtcctatct tcagaagtct gtgcaacgct tgggcttgtc tttttaggag
    22501 gctcctatat ggcagaatct ttccgaagtg ggctggaagc catcagtcaa acccagcagg
    22561 agattggcct cgctattggt ctgacacctc tacaggtctt ttactatgtg gttcttccgc
    22621 aagcaacagc ggtggcactc ccctccttta gtgccaatgt cattttcctt atcaaggaaa
    22681 cctctgtttt ctcagcagtg gctttggccg acctcatgta cgtcgccaag gatttgattg
    22741 gtctctacta tgagacagac attgcgctag ctatgttggt agttgcttat ctgatcatgc
    22801 tgctacccat ctcactggtc tttagctgga tagaaaggag gctccgccat gcaggattcg
    22861 ggaatccaag tactctttca aggaaataat ctcctgagaa tcttacaggg attgggcgtt
    22921 acgattgaga tatccatcct gtctgtcctc ttatccatga tgttcggaac agtcatggga
    22981 atcatcatga cctcccattc tagaatcata cgatttttaa cacgattgta tctggacttt
    23041 acccgtatca tgccccagct ggtgctactc ttcatcgttt actttggctt agctcgaaac
    23101 tttaatatca atatctcagg tgagacttca gctattatcg tttttaccct ctggggagca
    23161 gctgaaatgg gagacttggt acgtggagct atcacttctc tccctaaaca tcagtttgaa
    23221 agtggacagg cactcggctt gactaatgtt caactttact accacatcat catcccacaa
    23281 gtcttaagaa gactgctacc gcaggctatc aatcttgtca ctcggatgat taaaaccact
    23341 tcattagttg ttttgattgg ggttgtggaa gtgaccaaag ttggacaaca aatcatcgat
    23401 agcaatcgcc tgaccatccc aactgcttca ttttggattt atggaaccat tctagtctta
    23461 tatttcgcag tttgctaccc tatttccaaa ctatccactc acttagaaaa acattggaga
    23521 aactaaatgt ctgaaactat cttagaaatc aaggaactaa aaaaatcctt cggagacaat
    23581 cccatcctcc aaggactttc tctagaaatc aaaaaaggga agttgttgtc atcctagggc
    23641 catctggttg tgggaaaagt accctccttc gttgcctcaa cggcttagaa agtattcaag
    23701 gtggagatat tcttctggat ggtcagtcta tcgttgaaaa taaaaaagat tttcacctag
    23761 ttcgccaaaa gattggcatg gtctttcaaa gttatgaact ctttccccat ctggatgtct
    23821 tacaaaacct catcctaggc cctatcaaag ctcaaggaag ggacaagaaa gaagtaacgg
    23881 aagaagcttt gcaattacta gagcgtgtcg gtttgctgga taaacaacat agctttgccc
    23941 gtcaattatc tggtggacag aagcaacgtg ttgcaattgt ccgtgccctc ctaatgcatc
    24001 cagaaatcat cctttttgac gaggtgactg cttcgctgga tccagaaatg gtgcgtgagg
    24061 tgctggaact tatcaatgat ttggcccaag aaggccgtac catgatttta gtaacccacg
    24121 aaatgcagtt tgcccaagcc attgctgacc ggattatctt cctcgaccaa gggaaaatcg
    24181 ctgaagaagg aacagctcaa gccttcttta ccaatccgca aaccaaacga gcccaggaat
    24241 ttttaaacgt ctttgacttt agccaattcg gctcatatct ataaaggaga ttcttatgaa
    24301 actattcaaa ccactcttaa ctgttttagc acttgccttt gcccttatct ttatcactgc
    24361 ttgtagctca ggtggaaacg ctggttcatc ctctggaaaa acaactgcca aagctcgcac
    24421 tatcgatgaa atcaaaaaaa aagcggtgaa ctgcgaatcg ccgtgtttgg agataaaaaa
    24481 ccgtttggct acgttgacaa tgatggttct taccaaggct acgatattga actagggaac
    24541 caactagctc aagaccttgg tgtcaaggtt aaatacattt cagtcgatgc tgccaaccgt
    24601 gcggaatact tgatttcaaa caaggtagat attactcttg ctaactttac agtaactgac
    24661 gaacgtaaga aacaagttga ttttgccctt ccatatatga aagtttctct gggtgtcgta
    24721 tcacctaaga ctggtctcat tacagacgtc aaacaacttg aaggtaaaac cttaattgtc
    24781 acaaaaggaa cgactgctga gacttatttt gaaaagaatc atccagaaat caaactccaa
    24841 aaatacgacc aatacagtga ctcttaccaa gctcttcttg acggacgtgg agatgccttt
    24901 tcaactgaca atacggaagt tctagcttgg gcgcttgaaa ataaaggatt tgaagtagga
    24961 attacttccc tcggtgatcc cgataccatt gcggcagcag ttcaaaaagg caaccaagaa
    25021 ttgctagact tcatcaataa agatattgaa aaattagcaa ggaaaacttc ttccacaagg
    25081 cctatgaaaa aacacttcac ccaacctacg gtgacgctgc taaagcagat gacctggttg
    25141 ttgaaggtgg tcattaactc ttaaaaggga ctggatttta agctccaatc cctttttaag
    25201 attttaccta taacatcctg agtctatcta agatgttcaa tctgaacaca gtgtacatac
    25261 tttatcttct attgcatata ctttatcaca taagatacga atatcctctt cactatgact
    25321 agcaatcaaa attgttgtcc ctttttcact agagagcttt ctaaacaatg ttctcatatt
    25381 ttctacactt gatttatcca aggcattcat aggttcatct agtaaaagaa tagagggatt
    25441 ctccatgatt gcttgagcaa tccctagctt tttcctcata cctagcgaat aagttttaac
    25501 tttctggtct ttttgctcat atagaccaac tattttcagt gtatcattga tttcctgatt
    25561 accaactact cctcgtatgc ttgccaaata ttgtaaattc ttaaagccac tataataatt
    25621 tataaaacca ggttcttcaa tcaaagctcc caaattagct ggaatttttc tctcaggaac
    25681 aatattttcc ccattgatta acacttctcc ataagacgga ctatataaac cagctattaa
    25741 tttaaacaat acacttttcc ctgagccatt cgcaccagta attcctataa tttccccctg
    25801 tttacaacta aagttaaggt tttgaaaaac acatgtcttt tttaatttca actcaatatt
    25861 ttttaatata attatttcat tcattctata aacctcctct tttgacgagt gaaatagaaa
    25921 atgctttgaa aaagaaagac taaaaatagc aactgaagaa acaaatctcc ccctacatcc
    25981 ccattccctc gattcaaaat ataaaataga taattagttc gatttcctac aaatagacca
    26041 ccaaacacaa tcatgagtaa aaagaaacta acgcaagcaa agttcatttg tacattcgct
    26101 cctagtgcgt ataacataaa gcaaaacaag actaacacac aagcattcaa agaatcaact
    26161 ataaacaaaa ctcctatatc ccagtttggt aactgtaaca taaattgaat cactagaact
    26221 tttaccatga ttaaaatgag tccataaaga aaacaggtcc aaatctgata cctaatccag
    26281 agcttaatag aagaaaatcg aatcacttcc ataaagaaat cggatgctct tctacgatat
    26341 acaactgcta gaaaaaatgt atgaataata aaccaatgaa gcaaccatat agataagact
    26401 aaaaaagagt tttgactcag attaggccct tttaaaattt ctataacaag tctatcattt
    26461 ccttctaacc aataccataa tcctaaacaa atcaatatcc aaaaaagaac ataaccccaa
    26521 aagtacttgg tatagattat cttattcaac ctccacatgt gactacttaa ctttcccatt
    26581 tccaactttt acactctcct ccagtttcta tgaacagaaa atacagtcaa tggaattatg
    26641 atagatagta atgtaagcca ataaatcaat gcatacggat tggaatttac catatactga
    26701 aaaattggca ataatccaat tatcccattg ttcaactgat aaatccagaa taaggattct
    26761 acaaataaaa aagtaaacag aaatactaag ctcatgtttg attttttaaa ccaagaaaaa
    26821 ctgctaatag taagtaagga taaaaagaaa tagtatgcta tataagagaa aaaaaatcct
    26881 ataaagaaac tagcattgtt tgcaatactt ataccataaa attctcttaa aaaatcaacc
    26941 tcctttatct ccaaagagaa gctaaaacca ttactaaatg caattagaaa aatcaataaa
    27001 aataaagtcg ccgtccaaat ccccgtacta agagctgcta atttgaaact aaaactggta
    27061 aagtgcttaa ttgatttcag acgaatgcga cactccaacc tattaaaata gttattcatc
    27121 aaataaaaaa agaacaatat atatgtgaac ggaaagcaat atactccagt cgtcatatct
    27181 tgaagtaaaa ctaaaatcca ttctaataca tttggatgga ttgaatattg gcgacagcgc
    27241 aataaatata ctgtactaga taaaacacag gatagcagta atataaaata aaccaatact
    27301 gataaaaaat cttttttgta aaattgaaca aattgtttca ttatacatag tcctctgaat
    27361 gtagaaaaaa tgtaccataa acaaccaaac aactaacaaa taaaataaaa gcaagatgcc
    27421 cactaactaa ggaaagactg atatctttct gatatcccaa agctaatgtt gtcacaggtt
    27481 ctaagtaaga tagccctaaa atagcccaaa aaataccacc aaccatcata taggcaactg
    27541 ggatgaaaat agctcctatt tttttcttca ctagcaaagc actagctagt ccaaaaatag
    27601 agaacacagc gccccaaact ccataccaga gagtcgtcac aagactatag agcaactgat
    27661 tagaatcaaa taattctttt aaggcaccac tataatctcc aatataaatt tcctgataag
    27721 gagtcactaa aagattaatt cctaataata ataaataggg gagaaaaaag actagaaaag
    27781 aagaaataat tgcagtacta cctacaatag ccagatactt ctttttagaa attcggcaca
    27841 attgtgctgt tagaaaatga ctctcagcat cctctattat ctgactagaa tagggcagtg
    27901 tacagataag tgcagctact aggctaatcg gtgaaaatcc tcgaatagaa gaagcggcaa
    27961 aaaaaatcga taaaccttca attttataaa taccattgaa agcaaggaaa tttcctaaac
    28021 tcatgcaaag aagggtcaaa aataaagaca tataaaatcg aggtgattga acgactcgta
    28081 caagattaca aatgaaaaat tccatcctta ctcctcctta taataaaaat agggtgtagc
    28141 attctttttt catgctacac ccacaatcaa ccatctttaa ggcttactct gacaagtaag
    28201 ttaataagaa tctggactcc aagaacctga agtatgaatt cttacatgat ttccaaattg
    28261 tggcgccata gctaatctag taccagaacc aatataattg tcaccacctc cattatagta
    28321 catgacaatc ctagagccag accccaatga atataccggg gtaatatctg acccactata
    28381 ggcgctacga atagaggtat ttaacctttt accgccacca gtgctgtcac tattattaat
    28441 tccagcagag gcgttttctt tctcaagctc actagttgta tccgaacccc aacgcggcaa
    28501 cgttaaatca taatttccaa tctgtctagc taaaactgta gggagaaaca aactagatgc
    28561 aattgtaact acgcaaaaaa ggaatatatt tttcttcttt tcatgacatc gtcctcttaa
    28621 gaagtgataa acaagatagt tgattgatca atttgataca tattacattt tcattatatc
    28681 aataaaagaa agcgttgtca attattttat ttaaaatatt gtcatatttt aaataaaatg
    28741 gtaaaagaga ctcggtagcc tcgtctctct ttatcttact gacctaacct tcttgccaat
    28801 tttcttggtc ttctttaaag cgttttagaa gatcaaggcc ctctggcgtg atgtaacctt
    28861 cttcttgggc tagatggata agctctctat agtttgaaag cgtcacaagt ttaacaccag
    28921 catctgcaaa gttcttatct gcttttggca attggtagct gaaaatcgct acaactccaa
    28981 gtacatctgc tccttctcgc ttggctgctg ctacagcttc aagaactgaa ccacccgttg
    29041 aaataaggtc ttcaaccact accatttttt gaccttgagc tacgcgacct tcgatttgat
    29101 taccagctcc gtggtctttt ggtttgctac ggatgtaggc aaaaggcaag tccatcttat
    29161 cagcaataat ggctccgtgt ggaatccctg ctgttgcagt tcctgcaatc acttctactt
    29221 caggaaaggc ttctttaata gcttccacaa aaccattttc aattagggta cgagtttctg
    29281 gataggctag tgtcacacga ttatcagtgt aaatcggtga cttgatacca gatgcccaag
    29341 tgaagggttc ctctggtttg aggtaaacgg cttggatttt caagaggtgg ctagcgatat
    29401 ctttagcaag tgtcatggta ttctcctttt atttttctaa tctagttctt taattccagt
    29461 tctgtgtcca ttcatccttg atggcatgat aagctgcaac aggatcctca gcttgggtaa
    29521 tgggacgtcc cactacgata tagtcactgc cgatttgata ggcatcagca ggtgtcatga
    29581 ctcgtttttg atctccaact gcaacaccag ctggacgaat ccctggtgtc agacagataa
    29641 aatctggatt ggtagcctgc ttgatgactt gtacttcctg agccgagcaa acaacaccat
    29701 ccaagccagc ttcagctgtc ttcttggcat agtgaatcac agactcttgc agactggttt
    29761 ggatattttg aaactcctgc atctgagctt ctgacgttga tgtgagctga gttacagcga
    29821 tcaatttggc ttgactccca agaccttcac gcgccgcctt catcatctct acaccaccag
    29881 ccgcatggac attagtcata tcgacaccaa gctgagacaa gaccttcatg gctgacttga
    29941 ctgtattagg aatgtcatga agtttgagat ccaaaaagac actatgaccc aaacctttta
    30001 agtaggacac aatctcaggc cccgctgcgt aataaagctc catccctacc ttgagataaa
    30061 ggctttcttc tgctgggaaa agagctaaaa attccttgac cgcctcaaaa ctaggaaaat
    30121 caagagcaat gattggacga tgttctcgca taggtttctc cttttacctt tactagtgag
    30181 agagtctggc caacagaagc cacgaaaaaa ggaacctgcc aacagcaagg ttccacgaaa
    30241 aatgggtagt ctccaccctt tcaccgtcta accttagctg cctctctgga ctgctttaaa
    30301 ggttttctat tattctatta tttctactag cacttgtcaa gtaaaaactt agtcacgtat
    30361 gtgttgactg ctattgaaca cctcacaaga ctctttccaa aagaatagtt aaagactttc
    30421 acttaggaca gagaaaaaga gtttgcttgt taccctttaa ttgaacaaat gggaattctg
    30481 ttttattttg cggatgccta ttcatcttgg caaaggggaa gtaatgagaa tgcgaatgga
    30541 cttcttcgtg agtattttct taaaccgatt tggcaacaat taccgaaaaa atccttaatg
    30601 gtgctttgct agcttattaa tcaccgtccc caaaaatact tggattacaa gacaggtttt
    30661 gaagcactta tagaggaaat ttaaaaatgt tgcatttttt attgcaattt atcagttatc
    30721 ttatcaccca aaacttctgc aattagtatg agcactattg ttatttttct tttttcgtac
    30781 actcaaatca aaatatagca ataagactat tctgtagaat tgctgtcaaa aagatcagtt
    30841 catttttcct tcccacttgt gtttataatc attaaaataa ctcaattaag aaattttctt
    30901 tttcctaata gttatcgtaa ttaaagttaa tagaagaaca atccaaataa gtagtgttag
    30961 attaggaatt agagttttat tccatgaaaa tccctcccat tttgtgaaaa acttagtaaa
    31021 cagtcccata aaactataat ctgttatctt cgcaactgtc ttatccaaac cagatagcat
    31081 cggtaagaaa gcaactaaaa tcatagcagg aagactgata acctgagcta ctacttggct
    31141 cttcgcggtt aaacctatca ataaatagaa taaaatgatg gataaagagg ttagaagaac
    31201 gattgtaata taattaaaag tatgtacaat tgtaactcct aaaataagag gagtagttcc
    31261 cataatcaca aaagttagca aaaaaggaag aaacatcgtt gataaaatgt attcggatcc
    31321 tttaacacca ctcaacagaa gagtttgtaa attgtacttt tctttttctt cagacaagat
    31381 aatagttata ggacttccaa cagccaaagc caaagaaaaa ggtaaacaca tcatcaaaag
    31441 aactaatgcc tgttgatcgt tgaccttccc ctgtgtttcc ataagatatt tataaaaata
    31501 tgtgaaagca aaaggcacta aaacttgcaa taaaatactc ttattggaaa ggataatttg
    31561 acaacgcaac cataccaaag ccagaaaccg tttaagcatt tagctttcct cctgttaatg
    31621 tgataaaaat atcttctaaa gtaggctcac atgaatgaat tgaaaaaata ttttccagat
    31681 cagcctgaga tacctgttct agtgatgtaa aatcaaaagt tatctgattc ccattataat
    31741 ctgtaacctt aatcttttta tctttattat atctttgaat gagttcagaa ggagctcctt
    31801 gctcaactaa tttcccttta tttaataagg caacataatc acataaaaga gttgcttcat
    31861 tcatatcatg agtcgttaga aaaatcgttg tccctgctgt tttcaattct aaaattaact
    31921 catgaattgt tcgagaagtt gtgggatcta gacctgaggt cggttcatcc agaaagagta
    31981 cagcgggttt gttgataaga gctcgtgcta aaagcattcg ttgcctcatt ccagtggata
    32041 attttcctgc taccatcttg cgactatcat ataatcctac tcgctttaac aaattatcaa
    32101 cacgtgattt actaatatta taaaatttac tataaaaaag aagattgtta tacagagaca
    32161 ttttctcata aaatccactt gtatcgctaa ccaatccaat tctctttaat tcaccgcttg
    32221 ttaaattttg agatttttgt cccaaaataa tagattgtcc tttatcggca aggaactgcc
    32281 cagtcagaat attaatcgtt gtggtctttc cagaaccaga tggtcctaaa aatctaacct
    32341 tctttaacag tgaagcttat attatttaaa gctattttat caccaaaact ttttgataaa
    32401 tggctaactt caatcatact cattgcacct cctttatatt ctacattttt acttaacatc
    32461 tatttactta tctttatcaa ataaacgtct taaaaaaaac aataacatta agcatataac
    32521 cgttagcaag attgtttcaa tattattgat aatacgatac attctcaagc agtataaaat
    32581 aattatatat atgcaaatgc tcattatacc tattttttta aacatactaa gcctccttgc
    32641 taaataataa agttatataa taactaagac acactatacc taacataata aatatccact
    32701 ggtaactgaa taaatgttct aaaattaaca agcaaaaata aaatctcaaa cgatgaaaaa
    32761 agccatacta tattttccaa tgatgtttga atatttttat tgtagtaagc ataatatata
    32821 gcaaaaataa tacccaagaa caatactatt aattgtgttt ctataacagt gaactgccca
    32881 atagcagata aaaaagctac tcctcctgat aataagcaaa aacaaactga acgaataaat
    32941 gttttcgctc taatattgtt atctttcact ttattatttt tttacaaatt ggacattctc
    33001 cgttttccag aacatatttt tcttgactta gagcatgatt tctcatatta taaacgtaag
    33061 cgttatctat taggatttca ttataacatc ccagaaatat tttaattatt aaattagtca
    33121 ttatccctcc caaaatagca ggcatctctg gtgtagtcgg ccactttgtc ttatcagata
    33181 aagtgtactt atttatatct ttgtttatat tccgacaacc aaagcaagaa ccgatggtag
    33241 ggatatatat tatcagtaat aagatagcat ccattaaacc ctcctgatat gtaggatatc
    33301 ttatgcgata cagcaaattg attgacaatt tttataatat caatgggcgt atcaattgct
    33361 ttaacgataa aatctatact cccatattcc gcaacaattt tttctaattc ttctactgaa
    33421 gaaactttaa tagaaatagg tactacctga acatctgaat tatacttgtg tattttttca
    33481 gaaagaacat taatcttctc cttaccaaca tccgactctg tataaagaat ttgcctattt
    33541 aaatttgatg gttctattat atcgtaatca gcgacaataa gtttcctcac tccatacata
    33601 cttagactta gagatatata acatcctaag gctcctgctc ctaatactaa tactgtttta
    33661 ttctgtattt tattatactc ttcattataa aataacgaat agtaaccttt agttctagaa
    33721 tatctactat caatatctat ctcatccgaa attaaaattt gttcatttaa tagttcaaat
    33781 gttagtttac tgcctaatac ttcttctatc tctaatagtt ccttacaact attaaataga
    33841 tcgttgataa attcttgcga aatttgaggt tctatagcta tttcccgcat actccgacca
    33901 cgcaaataca ttataccttc ttttttataa gcaaaaacat aactatttac gtagaacata
    33961 tttcgtcctt cctctcatat ataatataga aagcagtata gaaacaacca cccctcctat
    34021 actacgaaca ataatattag gtgtcaaaaa ctgtaatagt tgactcaaag ggaaataaat
    34081 aataacaaat gctattaaaa gttgaactat atattgaaaa ttcaagttat tattgttaga
    34141 attcaagtat cttaaaataa taccactatc atactgaaaa aaaggaattg aattaataaa
    34201 aatcatacct aagttaatga taaaaaataa gagtccaagc aatttatacg atgtgaacaa
    34261 taaaacaagt aaacctgtaa gtgataaaat cgaatttgaa gcaattcctg ctaacataat
    34321 tttcaaaaat tgttttttat tttttaagaa ttgcacccca cttaaatcta caaaaaaaag
    34381 ccaaattaaa caaaagtagc attattccac aatttgggat ctcaatttga taattattag
    34441 caattattgc atgactaaat tcatgtatcg ttgcagacat aataacaaca agcaaccaaa
    34501 ataaaagaat gtttagcgtt attggaaagt tttggaaatt agtcaaaata tccgccctat
    34561 aaatatacat aataaaacat tgcaaaataa gagccaatgg gaaaatacca aataggattt
    34621 tttcaaaatt cttattaaat cttttatagt ttaatttttc agataatgtt atattaaagt
    34681 cccaagatat tttaaaaata tttatctttt ttcgtgattt catagaatct ataagtccca
    34741 ttttactaag aacaatataa aatcttaaat aatatttctt ccctactaac actaataagt
    34801 ccgatatggt aaattcttga cctattagtt gctctaacca tttttttcct gtttcccaac
    34861 taatacatgt ttcttactag atggtatata tagatgatac tgtccctcat aaggagtagg
    34921 taatatctta atcttatcaa caattctcat aacaaaccta acctttaata aataaaagag
    34981 gggctaagta aaacatactc tagtccctca gtccgcaatc aataaaataa tgactaattc
    35041 tattaatctc ttgctgcaag actaatacgg aaaattcaaa tgactgtcta aaatgaaatt
    35101 gaaaaagctt gatgttagta aatgaacaaa cttcaacaac cagcaagagc aaggattgct
    35161 aaaccaaatc cgatacctgt tgcaagtcca gctgaaaaat cactaactgg tactgaaatt
    35221 tcttcaattt cctcaaataa aaagttatct tgcatgatta tcactcccta tctttttaac
    35281 aacaggctat tccaattaag agaactaccc cagttccaag taaaactccc ccaaaaattc
    35341 accatctgta ggggctacga tttcttcaat ttcttcaaat aagaatgctt catctgacat
    35401 atgtgttacc ttcttcataa aaaattattt tgtaatcgat tacattgcaa atgtaacata
    35461 aagaaaaaca gatgtcaaat attaaacgta agaacatggt cactaaagaa ctataagaga
    35521 aaaggtaaac ctagcgacgc gatgagcgct gggtcgtttg atttcgattg ctctcttcct
    35581 cttgtttttt ctgttcttct tcctgttttt tctcggcttc cttggcctct tgtttggctt
    35641 tttcctcagc ctccataatt aatttatccg ccacagtgta actgtaaatt ccagcttcca
    35701 tgtcgaccac actcggttct gacaattgtg gcttaatctt actgtaatat ggcagtttct
    35761 tactcatttc agatagagga accaagactt cgtccgaatc attcatggtc aatcgaatta
    35821 aatcggatgt caccttgctt ggggctaatt ccaccttttg gatagccgcc ttgagttctg
    35881 ggctaatttg agcaagttct gagacaaaaa ccttgatttg ttcactatca ttaaagagaa
    35941 ctgataaata agtttctggt aaactgttca gactcacaga actagtctca agctgaccac
    36001 tggaaagaat aggataatga ttttcaccag aaatatagta ggccacaata tcatattcct
    36061 tgaccttaat agtgaactta gttggaaatt gatagacaag ttgagctgat tcaacccaat
    36121 agttagactt aatctgcttt tcatattttg ccttgtctag cagaaggtta atcgtataat
    36181 ccgaatcctg aatgcctgaa gcctgtcgaa tatcatcagc tgtagtttgc accgttccct
    36241 caacacgaat atctttcatg gtcgcataag gactgagcaa gtaggcagag acaatcaata
    36301 aaagcagact tggaaataaa atcgtgaagg ctcgcaagat atggatacca ggaatctttg
    36361 ctttggctgg tttttccttt gtagcctttt tagaaagctt tttatcctgt tcctccttct
    36421 ctttagactc tggttcttct ttctcttctt tctctttgtc agcctctgag gatgctactt
    36481 tttcttcaga ctcttcctta gctgattctg aatcttcctg gtctgtttca ctctcctggt
    36541 cctgtttgtc ctctgacttc tcagattctt ctcccattcg agcttgtctt tccttttcct
    36601 tctcctcagc tagagccgcc tcttcttcag ccttcttttt tagatattct tggtttcgtt
    36661 tctgccattc tgataactct ttcaattctt cgaggatttc tttgtcctca tttttcttat
    36721 cttttgacat ttactttcct tatgataaat cttttttcaa caattgataa aaatctgcta
    36781 gagatttcaa ttccttagaa gccttcatct tagcttggta atcttccttg tgacttagta
    36841 agtgagaaag cttctcttcc aaactatcca aggtcaaatc gctttcttga aggtcttctg
    36901 catagccttt ttttacaaag taagctgcat tttcaagctg gtcaccacga ctagcttcac
    36961 gaccaagcgg cacaatgaca tgcaattttg ctatcgccaa gagctcaaaa atcgtattgg
    37021 caccacctcg tgtcacaaca atatcagcca attccatcaa gggttgatag agatcggtca
    37081 catagtcaac acgaaaaaga ttttggctca actcattcag gctagaatct ccagttagat
    37141 tgataatatt gtagcgctct gttagttctt tcttatggtc tgtcaccaat tggttaaaga
    37201 cacgagcacc tgcagaaccg ccaacaaaca atacagtcgg caatttatga ttaaagtggc
    37261 tttgaatatc caccaattca tctggttctg gatttttttg atctgaaacc ttggccactg
    37321 ctcccacatg ctcaacctta gacaaactcg aagcttgctc aaaggttgaa tacatcttag
    37381 tcgcaaattt ataggcgatt ttattggcca agcccataga caggtcagat tcgtgaataa
    37441 agacaggcac tcctgacaca cgcgcagcga taacaggcgg tactgagaca aagcccccct
    37501 ttgaaaaaag ggtctgtgga cgaagtcgca acatgataaa gagcgattgg acgattcccc
    37561 agcaaacttt gaagacgtcc agcatatttt gccaagagaa atagcgacgc aattttccag
    37621 tcgcaataga atggaaggtg acatccaaac ctgacttaag gatttcttgg tgttcgatac
    37681 cacgcttgtc cccgatatag tggacttccc aaccatcttc gatgaacttg ggcattaaca
    37741 aaagattgag ggtaacgtgt ccaaccgtcc ccccacctgt aaagacaatt tttttcatat
    37801 tattctttta actccgctac tgtgtcgata aagaggtcgc cacgtacttc aaagttagca
    37861 tacatatccc agctggcatt ggcaggacta agaagaacca catctccttg agtcgcaagc
    37921 tcataggcct tgcgggtcgc atctgcaata tctgtcgcct ccacataagc gacaccagcc
    37981 ttgtctgctg cccgtttgac acgttctgca gattgaccca ggatgaccat cttcttgagt
    38041 ccagtaatgt ctggcaccaa ttcgtcaaac tcattgccac ggtccaaacc acctgcaatc
    38101 aagacgacct tgctgttatc aaatcctgac aaggcttttt gagtagccaa gatattagtt
    38161 gatttactgt cgttatagaa tttaacaccc ttgatgtcat ccacaaactg gagacggtgt
    38221 ttgacaccac cgaaggctga aagagtttcc ttgatggttt gattgtccac accacgaagc
    38281 ttggctacag caatagtcgc aagggcattt tccacattgt ggctacctgg aacaccgatt
    38341 tcattcgctg ccatgactac ttcaccacgg aagtagagtt gaccatcttc cagataagct
    38401 ccatcaacct tttcaagtgt tgaaaatggt acaacagtgg cttctgtctt ggaagtcaag
    38461 tcttttgcca agtcttgatt aaagttcaag acaaggaaat cagctgctgt catcttgttc
    38521 tggatattcc acttggctgc tacatattcc gaaaatgacc catggtagtc gatatgagtt
    38581 ggcatgaggt tggtaataac cgcaatctct ggatggaatt cttgaacacc catgagttgg
    38641 aaagaagaaa gttccataac aagcgtgtcc ttatctgatg ctatttgagc aacctgacta
    38701 gctggatagc cgatattccc tgataaaaga ccatgttgcc cagcagcagt caaaacttcc
    38761 ccaatcatag tcgttgtggt tgtcttaccg ttcgatcctg tgataccaat aatcggtgct
    38821 tctgaaatca aataagccaa ttccacctca gtcaagactg gaattccctt ggccaaagcc
    38881 ttttcaatca tgggattgtt gtaggggata cctggatttt tcaccataag ggcaaactct
    38941 tcatccaaga gttccaaagg atggccacct gtaatgacct tgatcccttc ttccagcaaa
    39001 ctttgggcag ctggattgtc ctcgaaaggt ttcccatcat ttactgtcac aatggcacct
    39061 agcttgtcca acaaacgagc tgcagattca ccagacttgg ccaaacctaa aacaaggact
    39121 ttcttatttt taaattgatc tattactttc atgtctcgaa ctccatttct actcctacta
    39181 ttttaccatt tttatggaaa taaaaaagcc acaaagtgtg tttgtgactc tttcttctaa
    39241 ctgaatctta ccatatcatc tatgtgataa atcggtaact cgaatgacct gatccacttg
    39301 ttcccaaata agaggattgt gggtcgcaat aataatggtc cgattcggat tttttaaaga
    39361 ttctaggatg gaaagtaatt cctcagagtt tttggggtct aaggaagtgg ttggttcatc
    39421 tgcgaggatc aaaggtggat cctttaaaat tatcttcgct aatgcaacac gttgtgcttc
    39481 tcctcctgat aactcaaata taggttgctt caaatccaaa taagagaggt ttacacagtt
    39541 tagagcttgt ttcatcaaag agattttctc tttttccttc aactttttac caactaaacc
    39601 cagattgaga ttctctttga cggtttggct ttcaattaag ccaaaatctt gaaataagta
    39661 tcccaagtaa tctctaaaga aaacagaagg cttgatgtcc ttaagagaag taccatcata
    39721 gatgatttgt cctttgtcat atggctctaa tcgtccaatc atattcaaga atgttgtctt
    39781 accacagcca cttgtaccga ttaaggcata aattttccca ccttcaaaat gaagatttgt
    39841 atctgaaaat agctgacggc ttccaaattt tttagatata ttctttagtt caatcatcct
    39901 attttccttt cataattgtc atagaaacac gagattcttt ctgcgcttga cggtaaagcg
    39961 tcagaactgc actagctaga aagactaata aagtgagcaa gccaatcacc aagtctcgac
    40021 tgcttaaaat aaagagacta gcaccaaata caaaactggc aaattgacta accatatact
    40081 gagcatgtgt ttcaaaaaat cgtaaacctg aaattcgttt aatcaaaata tctcggcgga
    40141 attgctcgaa atatagaaga ttgacagaat aaaatagtaa taaggaacta gctatcccca
    40201 caatagctcc taagattaaa gttgctgttt cagtttgaac ttcattataa cgagttagat
    40261 aaacacttct tccttcttta agataggata cttgctcata aattccagct ttcttcaaga
    40321 gttctagccc actctcatat cctttgataa agagttgttt tccagcattg atagaccaac
    40381 tagataagga tataaaacta tcacctgtag aagtcggcgt gaataccact aaaatcggat
    40441 cagtcaaata ctgagtagat acgggattct caccgttatt ataaacaaac cgcttttctc
    40501 ccattgaaag ataactaacg tgcgctttca tctcataatc caaaggagca cttgcctcct
    40561 caccagattt tccataataa ctcaatcttt cttcaaaaac tttcttaagt tctgcttctc
    40621 gagagcgcaa atgttctggg agcaagagga taaactcacc tttttggaga tgggctaact
    40681 tctgtttggt ctcagcatct accacgacct tttccttgtc caaataactg ggactaacat
    40741 agagcgtatt agcatctgga ctataggtat ccagtgtctc tccctgttca ttttttcctt
    40801 gtggattggc aaaatggagc agattatcct ttacataaag agcttgttct tcttcgattg
    40861 cttccttggc aaaggcatac cacttgctct gattttctgt atcttttcct ctatcaccta
    40921 agccaaaaga aatttgataa tagtctgctc tatcctgcca tgcttgtttt gaaatttcaa
    40981 gttctttcaa tcgttggtaa gacatcaaac ctgtcttaac agcgtagcct actgtaaaga
    41041 cagcaaccaa ctgacacaat agggttaaaa tcatcaggcg tttaaggggt aatctcccct
    41101 taataacggg aactaatgct ttgtaactca aactcattag ataaagaagc attagtaaaa
    41161 ttgaaatcgc caataaaaac aacagataga aactaatccc aaaaccatag gtggctaaca
    41221 agataggata aaacaaacct tgactaaaaa gaacgactcc cccacctagg aaggaaagga
    41281 gggctgatag aaggagccat ttgatatcag tagataaaga atgccccatg atggataaga
    41341 gagtctgacc agaaaagagt tttatacctg ctgctctcat ttccttaatc cgagtgataa
    41401 tcactaaagc aaagaaagat aagccaaata ttgctaaact aattaaaata aggggattta
    41461 gtaatattcg aaaagcaaga aaatagggcg gtatctttcg gtcagcactt gctttataac
    41521 ccaaatctcc taatttatcg gcaagctttt ctttcgtcaa ggagcctgac aaaaggagat
    41581 aactatttag cggatcacta cgttcacgac tttcttggct agcttcttgg aattcttttg
    41641 gtaaagttcc ctgaccataa gttgcataag taaagtgagt cgtcccatcc ttactcggct
    41701 ctacaattct tctagctatt aaactctgtt ctgagtttgc aaaattctcc aattcctgtt
    41761 caaatacctc acgcgtcggt tcctgagtat cttttttgac acgaagtaaa gaaacggaat
    41821 catagcttgc atataaatat tgtggcgcac gtaagacaat aatccaagca aggaagaagc
    41881 tgagaaaaaa agttgataat aatatgaata gtttcttcat agtagactcc ttgtaaacaa
    41941 aattccccct gtaatttctt acaaggggaa cgatttaaat caatgaacga ttagtcataa
    42001 tcacagtaaa atgctacttg ttctccccat ttagtccaaa tccatgcata ggaggttttt
    42061 ccagcagaag cttctccttt atctgaatga ctattccatc tacttacaag agaagaataa
    42121 tgatattttt taccatgata gtaatttgaa aaagcccaac cacctcctga accttctcca
    42181 tacgtccata ctcctccatc tggatattgt acagcagctg atgcagctcc caataatgta
    42241 aaacttgaaa taagagctag agcaagtaat ctatgttttt tcgttttcat tttatttttt
    42301 ctttcaaaaa aagcacacct tgagcaacaa tgcaacaaaa taaaccctcc tctctctttt
    42361 gttgaaaccg ctttcttatg tgataaaaat atcattttta ttatttgttg tcaaggaaaa
    42421 aatcgaattt tttagatatt ttactacatt gcctctatga ataatattat atagtagttt
    42481 tattttaaaa taatatgcaa ccagtactaa ccaaatataa aatagatgcc attaacgaat
    42541 tttattcaag tttttcccat tcatactatc caagcaaaag agatgatgtt atagtacaaa
    42601 acaattcaaa ctattgtaaa attcctagca aaaaagagag ccaaaactct cttttttatc
    42661 ttcttttact ttttttgact ggcatgagtg taatgtctct aacactaaag taagctagga
    42721 tcaacatggc tattgctagg aatatttctg ttggtaattg aaaaattttc agaaaagata
    42781 gaaccaataa aatcaagagt gccactaaaa tacataccat agcgacgata ttgactgtcc
    42841 ctttaatgct ttctggtgtc gcaaatacat agagtaggag cagtaaaatt cctaggacta
    42901 aatagaccat ctttctctct ttctagctct tattcagctg attttttctt cttgttagct
    42961 ttctcacgct ctgctttgtt aaggatttgt ttacgcaaac ggatagactc aggcgttact
    43021 tccatgtact catcgtcgtt caagaactca agagactctt caagtgtcaa gatacgaggc
    43081 gtcttgataa cagctgtttg gtccttagta gctgaacgaa cgttggtcat ttgttttgcc
    43141 ttcgtgatgt taactgtcaa gtcattttca cgagagtttt caccgatgat cattccttca
    43201 taaacctcag tacctgggtt gacaaagatc gtaccacgtt cttcgataga catgattgag
    43261 taagttgtag ccttaccagc atcgatagaa acaagggcac cacggtgacg tccaccaatt
    43321 tcccctggaa tcaatggcaa gtattggtcg aaggtatggt tcatgatacc gtaaccacga
    43381 gtcattgaca agaactcagt tgagtatcca atcaaaccac gcgctggaac aaggaagacc
    43441 aaacgagttt gaccattacc agttgaaatc atatccaaca tttcaccttt acgttcagaa
    43501 aggctttgga taacagaccc ttggtattct tctggagtgt cgatttgtac acgttcaaat
    43561 ggttcacatt taacaccgtc gatttctttt acgataactt ctggacgaga tacttgaagt
    43621 tcatagccct cacgacgcat tgtttcgata aggattgaca agtgcaattc tccacgtcct
    43681 gaaacagtcc atttatctgg tgaatcagtt gggtcaacac gaagggaaac gtctgtttgc
    43741 aattctgcct gcaagcgttc ttccacctta cgagaagtta cccatttacc ttctttacca
    43801 gcaaatggtg agttgttgac caagaaagtc atttgaagag ttggctcatc gatgtgtagg
    43861 attggaagag cttctactgc atctgtcgga gtgatggttt caccgacaaa gatgtcttcc
    43921 atacctgaaa cggcaatcaa gtcacccgct ttggcttctt ggatttcacg acgttccaaa
    43981 ccaaagaaac cgaagagttt tgtaacacgg aagtttttag ttgtaccgtc aagtttagaa
    44041 agggtaactt ggtccccaac cttaactgta ccacggaaga cacgaccgat accgatacgt
    44101 ccaacgaagt cattgtagtc caaaagtgac acttggaact gcaaaggctc atctgagtta
    44161 tctactggag ctgggatatg gtcgataatc gtgtcaaaga ttggtgccat agtcgcttct
    44221 tggtcagctg gatcatctga caatgaagaa gttccgttga tcgctgaagc ataaaccact
    44281 gggaaatcaa gctggtcgtc atctgcacca agctcgatga aaagttccaa gacttcatcc
    44341 actacttctg ctggacgagc tgatggctta tcgattttgt taacaaccac gattgggaca
    44401 aggtcttgtt ccaaggcttt tttcaatacg aaacgagttt gtggcatggt tccttcatag
    44461 gcatctacga ccaagacaac accgtcaacc attttcatga tacgctcaac ttctccacca
    44521 aagtccgcgt gtcctggtgt gtccataatg ttgatacgag ttccgttgta agcaacggca
    44581 gtatttttag caaggatggt aatcccacgc tctttttcga tatcgtttga gtccatagca
    44641 cgctctgcca attcagtacg tgcatcaagc gtttctgatt gtttcaataa ttcgtcaacc
    44701 agggttgttt taccgtggtc aacgtgggcg ataatcgcaa tgttacggat atcttctctt
    44761 aattttgtca tgatttcctc tataatattc aaaatttatt ttctaactga acgattatac
    44821 cataatttca aataaataac ataactcaag caagtgtaaa tgttttcact ccgcttttct
    44881 tttcacgtca agccttttca aagcaagcga cttatgataa gataggcaca gtatgcgttt
    44941 agataattta ttagcccaag aaaaagttag ccgaaaggcc atgaagcaag cactcctcag
    45001 aggggaaatt ctagtcgatg gttgcccagc ccgatcccta gctcaaaata tcgatacagg
    45061 actacaagaa ctcctttttc aggatcgaat cattcaaggc tatgaacaca cctatcttat
    45121 gcttcataag cctgctggtg tcgttacagc caacaaagac aaggaacttc cgaccgtcat
    45181 ggacctgctt ccatctgaca tccagtctga caagctctat gccgttggcc gactggaccg
    45241 agatacaacg ggactcctcc tcttgaccga taacggtccc ttgggctttc agctcctcca
    45301 tccccaatat catgtcgata agacttacca agtccaggtt aatgaacttc taacacctga
    45361 ccatatccaa gcctttcaaa agggaattgt ctttttagat ggtactgtct gtaaacccgc
    45421 aaaactagag attctatctg caagtccctc cctcagtcaa gcctctatca ccatttcaga
    45481 aggaaaattt catcaaatca agaaaatgtt cctctcggtt ggtgttaagg tgactagcct
    45541 caaaagaatc caatttgggg acttcacatt gaacccagat ttagcagaaa gtaactaccg
    45601 ccctttgaac caaaaagagt tacaaatcat taaaaactat ttagagatga gtcgataaaa
    45661 caaaaaaagc tttaaaacta aagctttttt cttttattta ccgaaaaatt aaggcgattg
    45721 ctacaatcca gttaactaca gaaatcacaa ttcctaagat attaagaatc ttttctattt
    45781 tatagtctaa ttgtgactct ttttggtatg aaatagccaa gaccaatcct atgataccca
    45841 aaatcaagcc tacaattgga aataacaaac caagaataat cgacaagata cccacaaaaa
    45901 gtggattttt cttcttttct ttcatgttct aagaactctt taaattttat acaaattaat
    45961 tatactataa aacaatagct tcatcctatc attcgactaa tttggaaata aggttagcta
    46021 gtcttcactt tccctttcca agaatccaag ccataagaaa ggatataaat ctcagaaaaa
    46081 ccttgttttt tcaagtaaag agctgcattt gtaactcgtt gcgcacgttg gttctcgtag
    46141 agaaggacag gtttatcttt acgaagggct gcaagactag ttttcaactg acttgaagga
    46201 atattgcgtg caccaaggat atgttttctg tggaattctg ctgggtcgcg caaatcaatc
    46261 aattgacccg tacgaatcaa ggcttcaaac tcctcattgt ccacaatttt agccgcacga
    46321 cgaatacgaa gatagttaaa gcccatccac gccaacattg ctagtataag tgcccacaaa
    46381 atccaagtaa ccattagttc ttttctccat ttttctcaat ataatccaat tctaccttgt
    46441 gctctctgcg aagaactgct tctgcctcta gatagtctaa tttatccatc aaccctgcat
    46501 cgtaaatccg agatagttcc aacttcatca gttcaatatc atataagcgt tttcccatgt
    46561 aaacaataat accaaatcgt ttgaggaatt gctgcacatc atagaatgtt ttcataagac
    46621 tcattctagc aaaattttgt gtttttttca agaagagact cacacaatgc tccttatttt
    46681 cctatcttct ttggcgattc taaggcaagt gtggtacaat aaaaacatga gaattcaaca
    46741 attacattat attatcaaaa tcgtcgaaac tggctctatg aatgaggcag ccaagcaact
    46801 ctttatcact cagccaagtc tttccaatgc tgtgagagat ttggaaaatg aaatgggcat
    46861 tgagatcttt atccgcaatc ccaagggaat caccttgacc cgtgatggga tggagtttct
    46921 ctcttatgcc cgtcaggttg tcgagcaaac tcagcttctg gaggaacgct ataaaaatcc
    46981 tgtcgcccac cgcgaactct ttagcgtttc gtctcaacac tatgcctttg tggtcaatgc
    47041 ctttgtctct ttgctcaaga aaagcgatat ggagaaatac gagcttttcc ttcgtgaaac
    47101 tcggacttgg gagattatcg acgacgtcaa gaacttccgc agtgaggtcg gggtcctctt
    47161 cttaaacagt tacaaccgtg atgttttaac caagatgctg gatgacaatc acctactagc
    47221 ccaccatctc ttcacagcgc aaccgcatat ctttgtcagc aagaccaacc ctctggcaaa
    47281 gaaagacaag gtgaaactgt ctgatttgga gaatttccct tacctcagct atgaccaagg
    47341 gacgcacaac tccttctact tttcagaaga gattctttct caagaacacc acaagaaatc
    47401 cattgtggtc agtgaccgtg ccaccctctt taatctcttg attggtttgg atggttatac
    47461 cattgcgaca gggattttga acagcaacct aaacggagac aatatcgttt ctatcccact
    47521 ggatattgat gacccgattg agctggtcta tatccagcat gagaaaacca gcctatctaa
    47581 gatgggcgaa cgctttatcg actatctact agaagaagtt cagtttgata gttgagaaat
    47641 gataagaacc aatatgtagg ctagcaacaa cctgcacatt ggttcttttt acttataatt
    47701 aaaagtttcc cctgccaact tatcagctag cttgggaaag agagtataaa acttatgggc
    47761 taggttcaac aaaatcggga gattgagttc tcgtttattt tttcctataa tcttgacaat
    47821 ctttttagcc actgcatctg cctctaagag gaagcggtca accgatttaa gataagttcc
    47881 atctgggtca gcttggtcaa aaaatcctgt tcggattgga cctggattga ctgttgtcac
    47941 atagactcca tagggcataa gttcgagtcg cagagcattt gaaaaaccaa tagccgcaaa
    48001 cttggtcgct gagtaaagac tagacttgcc agtagctatt agacctgcca tgctgacgat
    48061 gttgatgata tgccctttgc tgctttcctt catacgagcc gcaaggtgac gagacagatt
    48121 catcagggca aaggtattga cctcaaacat ctggtgaata tctttatcag caatctggtc
    48181 aaatccctca aaaatcccgt aaccagcgtt gttaatcaag acatcaatct tgccatagcg
    48241 gagataaaga tcagttacca gagcttctag ggctgaatcg tcggtaatat caatttcaat
    48301 caattctgca tgggaataat ttccgtagag ttgggctaat ttttccttat ttctaccaag
    48361 caagatgagt tggtcattgg gcaggagttt gaccatttct tgagctagac caccgctagc
    48421 tccggtaatg agaatagtag gcatacttat cctttctgtg actgctagat ttccacttct
    48481 tccaagtctt tgaccacatg gacattttca aaaattgtgg cagcgtcctt cttgagtttg
    48541 cttatatctt ttgagaggaa acgggcactg atatggttga gtaggaggcg tttggcacct
    48601 gcttctaccg ctacttgtgc agcttgcata ttagttgagt gaccatggtt acgagcaatt
    48661 ttttcatcac ccttgccata agtggactca tgaactagga catctgcatt gacagccaga
    48721 cgcacactgg catccgtttt tcgagtgtct cctaaaatag tgataatctt acctggacgt
    48781 ggcgctgaga tatagtctgc tgccttgatt tcagttccgt cttccaaaac aagatcctgg
    48841 ccgtttttga ttttaccaaa aagcgggccg aacggaacac cagcagcctt gagtttttca
    48901 gcatccagcg tcccttctag atccttttgc atgacacgat agccaacaca gaaaatagtg
    48961 tggtccagct cctctgcata cacagtgaat ttatcggttt caagaatttt acccagagaa
    49021 tcttggtcaa actcatggaa atgaatgcgg tagggcagac gagaacctga cacacgaagg
    49081 ctggttaaga caaatgactt gattccttga ggtccgtaga tttccaaatc tgtctgctct
    49141 tcattggcct gaaaggcacg gctagaaagg aaacctggca aaccaaaaat gtggtctcca
    49201 tgcagatgag taataaagat tttgctgacc ttacgtggtc gaattgtggt ttccagaatg
    49261 cgattttgcg taccttctcc acagtcaaag agccaaactt cgttaatctc gtccaaaagt
    49321 ttcagggcga gacttgaaac gttgcgggct ttagagggct gaccagcccc cgttcctaaa
    49381 aattgaatat ccattcgata ctttctaatt aatcaatata taacatggct gtgcggtttt
    49441 ccgatcggaa atagcgtttg ccagaaaaag cagcagcttc ttgcaataaa tcctcttggc
    49501 tgtagccttt gagacgtttt cgaccatcag ccaatctttc caaatcagtc aaagctgtga
    49561 gactttctag gctgacaact tcctcgtcct tgacaggctt catgtaaatc ttaccagact
    49621 cttcaaagac taattgatgg gagaaaattt gcgcaatttc aaagagcaag tcatccgaga
    49681 ttttctcctc attttcagag aaaatccgac caaagccgtc actctcataa caaaaaccaa
    49741 aggatttacc agacagatta agccgaataa aaggcttatt ttctagggtg aaacttggct
    49801 cagtattgta aagattcagt tcctgactga gttctgcaaa ataatccgtc gcagcctgag
    49861 gacttttttt ctgatagagt tctgcaaagt aggcattaac aacacttggc ggaggtgtaa
    49921 taagtgttaa ctgctcctgc tctgttttac cagctagaag ctgatccaga tagaccttgt
    49981 ccagacttgt ataacctcca tactttagag ccaaagtttt aatatcagtc ataaaattct
    50041 tctaacctcc atttattttt ctcggaaatg tagcctgtaa tcacttcgcc gtcttcctga
    50101 taatcacgtt cttccagaat tgcaacactc tctaaatcat gaatcttgta ggactttgaa
    50161 aaaggcactc gcagggtaaa tgcttcaaaa atttccttaa tcttatctag caataatgct
    50221 tgcaagtttt cacgactgtc ctcagacttg gcagaaatga gggtatatgg cgtttgggta
    50281 ggcgtgaaat cctccaccaa atccgcttta ttataaagcg tcaagtgagg aatatcttcc
    50341 atgtccaggt ctttcatgat ggagagaacc gttttttcat gctcctcgtg gtaaggattg
    50401 ctagcatcga taacatgaac cagaaggtcc acatgcttgc tttcttccaa ggttgacttg
    50461 aaactggaca ccaactctgt cggcaaatct tggataaagc caacagtatc tgtcaaagtt
    50521 acttggagat tgcctcccag atgaatactc ttggttgtcg catccagagt cgcaaagagc
    50581 tcatctgctt catactgggt cttactggtc aagatgttca tgatagttga tttcccagca
    50641 ttagtataac caatcaaacc aatcttaaaa gtgctagact ccaaacgttt ttctctgaca
    50701 gtcgcacgat ttttctcaac caccttaagc tggcgctcga tatccgtgat ttgattgcga
    50761 acgctacgac ggttcagctc cagttggctt tcaccaggac cacgggaacc aattccccct
    50821 gcctgacggc tgagcataat cccctgacca accaagcgag gcaagaggta tttgagttgg
    50881 gctaggtgga cttggagctt cccttcatgg cttcgagccc gcatggcaaa gatatccaaa
    50941 atcaactgca tacggtcaat gaccttaaca ccgagaactt cctctagatt gacattctgc
    51001 cttggggtca gacggttgtt gacgatgaca gtagtgattt cttctgcatc caccataagc
    51061 gcaatctctt ccaacttacc agagccgacg aaggtcttgg aatcatattt ttcacgtttt
    51121 tgtctgtagc tatctacaac gactgcccct gccgttttcg ctaaactagc caattcttcc
    51181 atggagaggt caaaactgtc cataccctgc aattccacac caatcagcag gactcgctcc
    51241 tcttttttct ccgtttcaat catctaaaaa ctcctctatc tggcttaaaa tgcggtcttg
    51301 tacaccagat tctccaatct gataaaaggt gacctgcatg cgattacgga accaggtcag
    51361 ctgacgcttg gcaaaacgac gggtcgcctg tttaagactc tcacgagctt cctccaaggt
    51421 ctgctctcca cggaaataag gaaagagttc cttatagcca attcctttag cagcctgtac
    51481 attaggggaa tggtcaaaca gccacttggc ctcatccaaa agcccagcct caaacatcaa
    51541 atccactcgg tggttgatac gctcataaag ttgactacgt tcatcatcca agcagataat
    51601 cagcggttca tacaaaatct cttgattttc caaatcctga ccaaaatggg caatttctaa
    51661 ggcacgcata gcacgacgac gattaaactg gggaatctca aggcctgctt gctccaccaa
    51721 atgggctaat tcctcatctg aatatggctc caaactagct cgataagcta aaatctcctc
    51781 atgaggagtc tccccaccta ggtggtaacc ttctagcaag ctctggatat aaagtccagt
    51841 cccaccggcg ataatggcta gcttgccacg gctgtgaata tcctcaatag tcatcttagc
    51901 ttctgaaaca aaatcaaaag ccgagtaaga ctcagttatc tctctaacat cgattaaatg
    51961 atgaggaaca gctgcctgct cttctggact agccttggcc gtcccaatat caagtcctcg
    52021 atagacttgc tggctatctc cactaaccac ttcgccatta aagcactttg caacttcaat
    52081 agctagagcc gtctttccaa cagcagtcgg tccaacaatc acaattattt ttgttttcat
    52141 cttttttcct tgaaaaattc ccattttttc gttactatta ttataacaca aaaaggtcag
    52201 tcagaaaaat gtgacctctt gaggaggctg gctgattgag aatataaagg aggaagactc
    52261 atggctaaag gattcgctaa aggtcttgta acaggtgtcg caggaactgt cgctgccgtt
    52321 gcaggtgcag tatacgcatt taaaaagaaa gtaatcgaac cagaagagca aaaagcagct
    52381 ttcatcgaag aaaaccgtaa aaaagcagct cgtcgccgcg tatcacgtta agaaacaaaa
    52441 gaagttggga ttattctcaa cttctttttt ctattctttt aaatagctag gtcaaacttc
    52501 aactgtggct taacagggtc ataatccacc aactcaaaat cttctgcttt gatatcaaag
    52561 aaattagtcc catcaggaac atttaaaacc aagcgtggtt ggcagtttga cggctcccga
    52621 cggagcaatt cctgagcttg ttcaaattga ttatcataga tatggaggtt gttgatgaag
    52681 tagaagaact tcccaacctt ccagccaaaa tgtttagcaa tcatcatctg caaagccaca
    52741 tactgcatag cgttgatgtg gtgggccacc agcatatcat tggagcgctg ggtcaaggtc
    52801 gcatccagat agatttcccc atcaacacgc cgaacatcaa acatggtctg aaaggcgcac
    52861 gggagcagcc catctgtttc ttcgaaagct tggtaatccc agagagaaat aatattgcgg
    52921 cggttccaag gattggtttc caactgtttg agaagcttat tgataatgtc gtgtttctta
    52981 acaacggcac catagcgctc accaatggtt cccgtgtctc caacttccca gtcattccag
    53041 tagtgaacat tgtacttgtc attaagcact tctaagctat ttgactggtc ttggtaaatc
    53101 cagagaactt ctttgatggc ggatttgatt gcaatgggac gcaaggttat gataggaaat
    53161 tctcctttag ataagtcgta ctcggaaaag gcaccagtta catacttgga attagcaaca
    53221 gtcccatcct tgtacttagg acgagcctgc tctgagaaaa caccttcctt tagaatgcgt
    53281 tcaatattct ctttaaaaat cgtatctgct tttgtcattt actctcacct cattcattgt
    53341 cctaactagt atagcataaa aaataaaaga ggaacattac taactctagg ttagcatttt
    53401 cctctctcat tatcttattg caatacaagt gatgctgctc cgataactcc agcgtcattt
    53461 cctagagttg caagagctaa tttagtagat gtgcgtactt gtgggaaagt attttcgtca
    53521 tagacttttt gaacaccttg tagaaggaat tctcccgcag ctgacacacc accaccgatg
    53581 acgattgttg atgggtttag gattgaacca atgttagcac aagcgattcc caagtaacgt
    53641 gagaagttac ggtaaacaat caaagcaagg tcgtctcctt cttttgcgag atcaaagaca
    53701 gtcttagcag ttacttcttc tccgttatca atcaagcgtt tcaaggctgc atcgccttcg
    53761 tattcatcgg catagcgacg agtcaagttg acaattcctg ttgcagaagc gactgtctca
    53821 agacagcctt tcttaccgca agtacatgag attggctggt caaagtcaac agtgatgtga
    53881 cccaactcac ctgctgcacc agcaacaccg tgaagcaatt tgccttctgc gacgataccg
    53941 ccaccaacac cagtaccgag tgtcataaag acaacatctg gttggttatc accagcaccc
    54001 atccagcgct caccaagagc tgctacgttg gcatcattat cgatgaaaaa tggaatgccc
    54061 aaagcttttt caatcttttg tttgattggt tgaagggttt tccagttcaa gttgtaggca
    54121 ccgataacag tccctttgtc acggtcaacc acacctggtg atcccattcc aatgccttgg
    54181 aagtccgctg ctgccaatcc aagcaagtcc aaacgatgtt gaatagactc aatcatatca
    54241 tcaacgatat gacttccctc atccaaaatg ttggtcttga ttgaccattt tccttggatt
    54301 tctcctgctg ttgttaagat tgcaaatttg atagaagttc caccaaggtc aatcccaata
    54361 atcttttgac tcattatatt ctcctttttc attgtgtagt aattgaaaat gcttacagta
    54421 ctagtatatc aaaatccatt cacttatgca aaggtttgcg taaatgaatt ataaggaatt
    54481 ttttcgccta ccagtatctg ttaaccatct aaatgatcaa tggcatattg agctgcatca
    54541 tttgaaaatt tatcaaaatc agaagttaat tgtctataca tacgtttttt tgacatgtgg
    54601 aataacgaat tataactttt tgcctttcct aaagcagcag aatattcact attgctatca
    54661 ttactagaag aagctgtact tgcttgacct tccttccaaa ctccgtcagc gccaacataa
    54721 taacgtccac catcaaccca ttcattgaca gccattttac catccgattt tagatagtaa
    54781 tttccttgcc atgtactata agcataagaa ccatctgatg tcaaataata ccaagcttga
    54841 taggtggcat cataaaccca ttcaccttta gccattttac catctgattt caaatagtag
    54901 tttccttgcc atgcattgcg agcatatgaa ccatctgatt tcaagtaata ccatgcttgg
    54961 taagaagaat cataaaccca ctcaccttgt gccattttac cgtttgattt aaggtaataa
    55021 gctccttgcc atgcattttt tgcataagaa ccatctgatt tcaaataata ccaagcttga
    55081 taagaagagt cataaatcca ttcactctgt gccattttgc catcagcttt caggtaatag
    55141 tttccctgcc atgcattttt cactagattt ccatttccat caaaatagta ccaagaaccg
    55201 tcctgcttaa cccaaccact tgctgtggat gaagttgtat cagtttgagt tgtagccgct
    55261 tgttttgctt taaaagcacc cttaggagca tttttcaatt cgcaagccac accatcatga
    55321 tcgcggtcta acttggcaga ataaccaggt tctccctcat gaagatccga atatccatta
    55381 gcccaagctt ccttacagct cgaaaaatgg atgttttctt ccgccaaaac tggttgtgaa
    55441 aacaaggcta aaattggcaa cgtcaccaga ctcattttta aaaatagacg tttattcatt
    55501 tctttctccc ataattatga tatcgatttc aatattattt tatcaaactt atttcagcaa
    55561 ttcaaggaaa cttctggtct tttctacaaa ctcctttggt tttgccttat tcaagacatg
    55621 agggccatca ggaatgatct gaaactgcga atctgttaac agtctatgga gagctttcat
    55681 agaactaaga ttcggtttat ctttgctgcc acaaattagt aaggttggat aggagcaagt
    55741 ccctgctata tccgttaaat caagtgtctt caattcctca gaaactccga ccataagagt
    55801 cttgtctgct ccctgttttt caaatactct tttgggaagt agtttaaaaa tcagcaactg
    55861 aagataaaat aggatattcc ctgctaattt aagcgggcat cctgacagaa tcaaagctcg
    55921 aagatttggt aaatcgtaac tggaaagttc tagtgtcagg gcagcaccta aggacaatcc
    55981 aatcaaaaca aaaggttctg tctcttgagc taggtgctga taaactcgct ctttagcttg
    56041 ttgatagtta ctaactccag aaggaaataa ctcgatagcc tcagaaggat aatctgtcag
    56101 tagattccga acttctttcc aagactctgc tgactgccct aacccatgca aaaatatcaa
    56161 tttcatctag ttctcctcaa ggcttagttc atacaagcct ctcactgcat tacagccgta
    56221 aatagcttct gcttgggtta aatctgccaa ggtcaagact ttctcttcta cctgtcctgt
    56281 ttctagcaaa tactgacggt aaattcctgg taagattcca agtcggatag gcggtgtgta
    56341 gagttttcca gcgattttca gaaccaaatt tcctatagag gtttcaagca gttctcctga
    56401 cttattgtgg taaatcttct cttgttctcc taggctcaaa tgcggtcggt gagtggtttt
    56461 aaagtaggta aaggattgat tcaaagcagc ttcctgaagg cagacttggg cctgacaaaa
    56521 gcttgtactg agaggggtta atacttgacg attgacttct atctctccag atttgctaag
    56581 gctgattcgc aagcggtaat ctcgattagc ttcacaatcc tgacactctt cctcaatctt
    56641 gtgtcccaag tcttctgcat caaaaggaaa agcaaaataa cgactagctt ttctcagtct
    56701 ttccagatgt tgatcttcaa acagcaggtt cttctggctg atttcccctg tcgtaatcag
    56761 ttggaagcga gcttgtttac gataaagaac tgctgccttt tgatgaacct ctcggtattc
    56821 agattcccat gtgctatccc aagtaatccc tccgccaact ccataaatgg cttgaccttt
    56881 gtgaagttga atggtacgaa tggccacatt aaaaatccgt cgtccatttg gaagcaagag
    56941 accaatcgtt ccacagtaga ctccacgcgg ttgaggctcc aagtccttga taatctccat
    57001 tgtcgcaatt ttcggtgcac ccgttatgga accacaagga aagagtgagc ggaagatttc
    57061 aacaaggtcc acatcctctc gcaactgact cttgatggtc gaagtcatct gccaaacagt
    57121 tgaatactgc tctacctgac acagacgctc cacgtgctcg ctcccaactt cagaaatacg
    57181 gttcatatca ttgcgcaaga ggtccacaat catcatattt tcagagcgat ttttgggatc
    57241 ctgttccaac caactggcct gttcaagatc ttcttggtca gttaccccac gctgagtcgt
    57301 ccccttcatt ggtcgtgttg tcaactcgcg atcattttgc tcaaaaaaga gctctgggct
    57361 catggaaatc actgccatct cgtcatgttc cacataggca ttgtagcccg cctcctgctc
    57421 taccaccata cgattgtaga tggcaaaagg attggcactt aacttttgct tgagttggac
    57481 ggtgtagttg acctgatagg tgtctccctg cctcaagtga tggtgtatct gggcaatggc
    57541 cttttcatag tctgctgcag acgtcacttc ctgccaattt gagggcaaat caatatcctc
    57601 ataagtcaga ggaatagggg aagtttctac gctatcatga acagtaaagt aaagcaggta
    57661 ctctcccagt aggggatcct tgtgaactgc taatttttcc tcaaaagcag gtgcagcctc
    57721 gtagctgaca taccccacca cataataacc ttgctcttgg tagctttcca cttgtgccag
    57781 caaatctgcc acttcttcta catttctcgt tttcaactct ttaataggct gggcaaaggt
    57841 atatctctcc cctaaagtcc taaaatcaat cactgttttt ctatgcatac cttaagtata
    57901 gcataaaaag gcagatacag acaaagctga tctacctttt tacgatttta ttcattctat
    57961 gcttgtggtg cagtaaatag atcaccagag aaaccgtctg tgtttttaag gagagcttta
    58021 aagactttcg atttcaagac aactgtattt cggtatttgt ctttaatact actatcgttt
    58081 agttccgtta aatctttagt aacagcctca tcaaacatag tcttcaactg ttcataggtt
    58141 gaaatttgag tgccattaat ttcaattggt gcaaaacctt ttttagattt tgtaagaact
    58201 tccccatacc attgcttctt ccaatcttca aggtttgaaa attggttatt agaaactttc
    58261 ttaataatga aatcatcacc taatagaccg ttattttctt tattggctgc accttgatgt
    58321 ttgcttgaaa catagtcaat gaacccatgt tcatatccat agtaacccca catacggaag
    58381 gcgttatgtt tgaaggatag agaaccaggg gcaccttgac tcgtattacc gccataaata
    58441 ccagccatca tattaacatt gacatatgcc gtaccaaagt cctctgggtg gaagacctta
    58501 ttacctggat ttccgtgaat ggtcatgaaa ttattattta ccaagtcatc gatggtttca
    58561 aggttagttg ttttctcagc gtctatcaaa tcacgcactt tgtcccattg gtgaggacca
    58621 cttagtttat ttctgtccat tggtcgacgt gtttcgcgat caattttctt gaaccactta
    58681 ctattgtcac ctttaacctt aggaagaaca gcctcagctt ctgcataatc gagcatcatc
    58741 atagcttcat tgtagttctt catgtaatgg tcgatttggt cacgtgtttg aagtttggta
    58801 ggatctggat tataccattg gtttccatca tttgaacgtt caaatgccat atttaatcca
    58861 agtgcgccat attcaccttg atgtccatgt tctgctggag tttgtaacat accttgagca
    58921 aatgcttcaa gatctgtacc ctgtcgatgt ctatgacctc ccagatatgc cattcggtca
    58981 tttacgtggg tagtctcatg tgtaaaggca gatgtgccat attcacttat taaatccgac
    59041 ataacaaaat atacagcatc cataggctgt ggatcagcaa agatgtaagc atacgctcca
    59101 tacccatact tataatcatg atacttatca atacgtccaa agaattcacg aataggtgca
    59161 taatccggtt tatcttttcg atgaccaaat ctatcaggcc aaccaccggg tgcaccatga
    59221 ttatcccata caggagttgg aactacattt tgactcttaa gaagtttatc gcggacatta
    59281 tcagtggcaa ggcgtgacca aaaatctaag taattaactt gctctttagc acgtttattg
    59341 atttcactct tgaacgattc acgtttttct tctgtatctt taccatactt ttcaaacgaa
    59401 ctaaatgaga tagtattata tgttgaaatc ataaataaat gtgcatcttt caagttcaga
    59461 agcgataaaa tcatgcgtcc atgttgtccg ttattaagtc cttcatatag acgatatttt
    59521 ttattagcaa atgcagggtt agttgacggt tgttcaacta cataagcatt attttcaata
    59581 gctttcttaa accaaacatt tatgtctgtt tcatttgtga atagtttcat attgtaggtc
    59641 aagaagtcat gtaagtttcc agaaagagta tttttcgcca ccacttcacg gaaggactcc
    59701 tgtgtacgac ttcccttaat atagtcctct tttgaaccaa tttctattaa tcgatctaaa
    59761 acacttacat tcttaccata aaaatctggt ttgaatagca ttaattcttt aatattgaag
    59821 ttatcaaatt tcacaccgta ataacgattt aggtatgtta atcctaacag gacagcagct
    59881 ttgttatctt caattttctt aatcaaggca cgttttgcag cttcatctgt attcagttga
    59941 tgatcttcat tttcaactaa ttttgtcaca aatgtattaa gatgatcttt tacttcttta
    60001 aagctttctt ctaagtaaag attcttaatt gcattaactc tgttatcccc agttcttcct
    60061 aatcgttgat aaattggatc agattgtaat tcaattggac ttaaaatacc ttcaatagca
    60121 ctaattaaat ctgcacgatc tttaacaacc atatttggtg tatagacgac ttcaccaagc
    60181 tctgcgacac tgtattcttt tacttgctta acttgagagt ctttaggaga aatcgtaaag
    60241 atatcttttg tcttatctgc gtaatgaacc ataatatggt cagcatctgt aaggtctgta
    60301 ataaagtcat tacctttcat tgcagtcaca gacaatactt ctttattcat taatggacta
    60361 tcagttgtaa gcttgttccc ttgattcaca atccattctt tgttgtagaa cggttggagt
    60421 ttttcaacat tacgataaac aagctcacga tttgcattat aatcttgaat tgttttgtat
    60481 tcttcatcac gtaatatacg gcgattcaac ttatcaacca aatgctcagt tacttcaaat
    60541 gtatcagcag tgatacccat atccttaatt ttcttatcag cttctacctg tgaaatttct
    60601 ttaattttag acgattgttt atgggtttta tctccagaac tcacaccgat aactgttgca
    60661 ttattaggtt taatccaatt gcttacaaat tcatcatcca tatcattaga accaaagaaa
    60721 atatcaccac gcttaacatt cactaagctg atattgttat caatggttcc ccaaggccag
    60781 tctttaccaa ttaaaccgcc tacatcacct ctagcaacat caatagtacc tttggctaca
    60841 gaatttctta cattagacca agcaccaaca tctcttggat taaaatcatg agctaaatgt
    60901 cctactatag cacctgcacg agtatttaaa cctttaagtt caacatctgc ataagcttta
    60961 tttaaattgc ctcgataaat ctcagatgca atcccagcca agttccaccc tttatcacca
    61021 acagattgaa cttttccgat aaaagcaaca ttagtcataa tacctgcatc atctaattta
    61081 tccaaaatac ccgcaacatt gttattacca acgatagtac ccgttacttt aatattttca
    61141 acagttgcat ttttcactgt ttgagctaat gaagctaatt gatttgccca aggcatatta
    61201 atattaacgt taattaaatt aatatttttg atagaacccc cttcaactct atcaaataat
    61261 ggacgagcag tgttatgaat ggagaaatgc ttaccatcaa cacttgttaa gtgacctgta
    61321 aatttacctg ttacatatga tttacttggt gtaggtacat ttgttgcatt taaatccgat
    61381 cctaatttaa actcaccgtt aggatttttc tgcatagcat ctactaaatc tttgaagtta
    61441 tagtaaacgt tattttgcga tgctttgggt ttctctatgt aataagtgta tgtttgactc
    61501 aaactattat ttgaatcacg ttggattaaa tcaggagctg aagcagtaac tttaaataag
    61561 gatgtctcct cctcagttac ttcctctata ttagtaatgg caagccttgt tactttatta
    61621 tgattagtgg taatttttag ataatatgac gttagatttt ctggaacagt ttctagaagg
    61681 ctactatctg tttcatttcc attctcatcc actttcatca atcttgtttc tttaatatct
    61741 ttaatctcaa cttttttaag gtctaactga acttctttat cttctaatat ttcagtttct
    61801 tcaccgttac ctcgatcata gaccatggtt gtggatagtg tataaccttg ataatatttc
    61861 aagttgtcta aagtagcttg taagttattt tcttctaccg ttacttcttt aacaactgtt
    61921 ccagtattat cttttagagc tactttaatc gatttaattt ctactccagc tggtttagtc
    61981 aatgtataac tagctgtcgc actcttcttc aagacatctt tatctgtttt agcccattcc
    62041 aaggttggtt tctctaactc ttttgtgcca ttcttaataa ttttgtcttg aggtttttca
    62101 atcactgttt ctgtgatagt aggagcgtca cttgtttttt ctccgcgaat tgttttatag
    62161 gtttcagtaa tttgtttctt atcgtttaca ccttcttgag ttacttgtct tgttccgcgt
    62221 tttaaagtgt catcttcttg ttcttttgtt tcaaaaggaa tgatttcttc tcttgtctca
    62281 accgttgtcc cttcaattgg ttttgtacca cggattacct gttgatttac aggctccttg
    62341 gtgacttccg tactggttga aagaacttgg tcagttttaa cccctcctat tgttttatag
    62401 gttgtttttg taacttgact tcctttttca ccatttcgta ggacagtttc ttcgtccgtg
    62461 tacttggttg ggtcctcagt cgtttcagtt ttatagtcaa gttctgtagt tgattcttca
    62521 acgagtgttc cttcagtcac cttatactca ggtaattgtt ctggaacaag agcctcaccc
    62581 acgtaatctt cttcttgcgt ccccttagct gttttagtct cctcttttgg ttctacagtt
    62641 tcttcagcct tggtatctgg agttgactct tcttgtttcg gtgtctcttc cgctccccta
    62701 tcttctttag gattgtcttc ttgtgatgat tcttttggtg tacttggttg ctcagcttgt
    62761 gtaggttgca cgggttgttc tgggactttt gcttgttcta ctggtggttc aacttttgat
    62821 tcctcagctg gtttgtctga tggttgactt tctggcttaa ctgctacttt ttcctctgat
    62881 tttgactcaa cttctccacc tacttcttca actggagctg gttctgctga atcttctttc
    62941 ccctcttcta ctttaggaag ggtgtcgtca gtaggtttta cctccgattt tggttcttcc
    63001 tttggacttt cttctgttct aggtgcttct tcttttggag tttcctctgt ctctactact
    63061 tggttttctg tcctagcttg ctcctgattt gttgttgatt gaggagtctc aacttcgact
    63121 acagtcacct ctccaggttt tgctgaggtt tcttctaaaa cagtgtccaa gccaagcgtt
    63181 ttgaggatgt cacctgatag ataaccaaca tagcgatagc catccatttc aacaacaccc
    63241 tctcgactag ccagcgctaa ggtcgcaact gggtctacag cccctgcact aggaagaact
    63301 accaatccca tagctccaac tagaaagacg ctagcaattt tctttctctt gtagattaaa
    63361 agcaagctcc caacagtcag caaaccaaaa gctgtcaaaa cagatgcttc tgtccctgtt
    63421 tgaggcaact gatctttttg atacaccaaa ccatatacaa cttcattcct gtcaggcttt
    63481 cctgtctgaa ttaaatcttt agcttcttgt gaaataatct ctttatttac atagtgatag
    63541 gtagctgcgt ccactacaga aggagccatc aaaaggcttc caagaaatac agagcctaca
    63601 actcccttaa tcttacgaat tgaaaaacgg tcttttttaa acactttcat ctcctttatt
    63661 cattctcaag actttctaat agcatcttgc ggatagtgcg cacgcgcacc tccgattaat
    63721 tttggacgac tagccagtgc cgttacatgg gcatgaccaa tctctctcaa aatagggcga
    63781 atcggaacct gaacatgctt gacatgcatg ccaattgcag tgtctccgat atccaatcca
    63841 gcatgagcct tgataaattc aacctcaact ggatcctgca taaacttaaa ggctgccaac
    63901 tgccccgaac ctcctgcatg aagagtagga tggacactga caatttccag atcaaactgc
    63961 tctgccacct gacgttcaac aacgagagcc cgattgacat gctcacaacc ttgaactgct
    64021 aaatggatac ctctactacc tagaataccc aagatagtct ccactatcag ctcaccaatc
    64081 tcttgactgg attctttccc aatctgacca cctagcacct cactagaaga tagacctaaa
    64141 acaaaaagga ccccctgctt caaattggtc ttttctaaaa catcttccac tacctgacgt
    64201 gtttctcttt gaatctgtgt ctcgttcatc tctgttacct ctgttgtcac tcttctatca
    64261 taccgttttt tcttgttttt agcaagatag acaacctata aagtctgccc aattacgcat
    64321 aaaactccca gaattgactg ggagttagct agtttctatt ctatttatat atatttcaac
    64381 tttcgttcct ttttggggtc tagaatcaat cttcatctgg taattggctc caaaatgaag
    64441 tttgagccgt tgatcgacat tttgaagacc aactccccca cgtttgagtt gactttgact
    64501 actatcacca gcatcttgga agccaacgcc atcatcctca atacggatga ccaatcccga
    64561 atcctgtttc tggacagaaa gtttaatatg gccctgacct tccttttcct taatgccatg
    64621 gtaaagagca ttttctacaa ggggttgtag gaccagcttg ggtaagacta aattatcaaa
    64681 ggcaacattt tcattaattt cgtattccag cttatctcca tagcgttgtt tctggataaa
    64741 gagatactgg cggacatgat tgatttcgtc agagagacaa atcaagtcct tgccttgatt
    64801 gagcgccaag cggaaatagg ttgccaagga cttggtcacc tgcaccactc gctgactatc
    64861 atgaaattca gccatccaga tgatggtgtc caaagtgtta tagaggaaat gtggattaat
    64921 ctggctcgaa agggcttgaa gttggtactg acgggtcgtt tcttcctggc tacgaatagc
    64981 taccatcaac tgatcaatct gatccaacat agcattaaat tggcgagtta cttctctcag
    65041 ttcataggca ccaacttcct tggcacgaag attttgagca ccagaagcaa tttccaacat
    65101 ggtttctctc aaatccttca aaggagcaat ccagcgttta agactgaacc acactaagca
    65161 gagacaaaca agaagagatg tgacactggc cccaagcaag gtccacaaga gctgactccg
    65221 aacctggtct aacttttcca atgatgacac gccaagtacc gtccaatcag ttcctgcaat
    65281 cttctcttga ctgacgtagg atttgtgacc aggagtataa ccctgacctg tctcgatgta
    65341 gggtttcata gcctccattt tgctagacga actataaact gtgtgttgag gatggtagac
    65401 aaattcatgg ttttcattga taatgaaggc aaagccctgc tgccccaact ggagttgatt
    65461 gagataggct tccagagttt cataagaaat atccaaacga agcacaccaa gattggctcc
    65521 ctttgcatca acaagttctt gagtgacaga aatgacccac tgactatctg atttacgagc
    65581 tggagtcaaa acaggcatag ctccctgatg aatagccttt tggtaccaat cctcagccat
    65641 catatcagag gaagttttca tctgcacact gtcatctgta gaaatgacct gaccagattt
    65701 ggtcaccagc acaacagttt tcaagtcctt atctgacttc aagatggtca aaaacaaatc
    65761 tcggattccc tcgaccttgt cttgactggg attctcagca taggccagaa catccgtctg
    65821 ctgggtcaaa ccagtcgagg tggtttctag ttttttgata taagactgaa taaagtggct
    65881 agtctggctg atggtcgttt ggctgttgcc ctcaatggtg gcctcaatgg ctgaagaact
    65941 tgattgatag tagaaagttc caaccagagc taggagaatg agaaagacca gaaagatgga
    66001 aataaccatt ctaactaaaa gagaagaacg cttcatcggt cttctccctt cttaaactga
    66061 cgaggtgtca cacctgcaat ctgcttaaaa cgttgggtaa aatagttcat atcttcaaaa
    66121 ccaaccttct ctgcgatctc ataaatcttc agatctgtag ttaaaagcaa gagcttggct
    66181 tgtttaacac gttctctcac cagataatcc tgaaaaggca agcccaactc tttcttaatc
    66241 aaggaactca gataggtcgg actaaaacct aagtcactgg ctaaagactt taaactaaat
    66301 tggctatcag ccagatgaga ctggattttc tgggccatgt ttccttcaaa cctattagtc
    66361 aataaatctt gtaactgctc ttctttctct tccttgtcta gtttttgttt gattttcccc
    66421 aacatttcct caatatcctg acgagaaaag ggtttgagca ggtagtcgtc cacacctagt
    66481 ttgacagcag acaaggcata atcaaaatca tcgtaacctg ttaaaaagac caaatgaacc
    66541 tgaggatagg tttctcgtac cagactggcc aactggatgc catttagatg aggcatgttg
    66601 atatcggtta aaatgatatc tggcacctgc ttttggatca attcccaagc ctgccttcca
    66661 ttttcagcct gaccgatgat ttccatatcg taggctgcta cattgaccag tttagtcaaa
    66721 ccttgtctta ccagatattc atcttctacg attaagattg tgtaggtcat gctctgctcc
    66781 tttaccactt actagtatca gtatagcaaa attctcctct aactgcttag gaaagacctc
    66841 ttatactcaa taaaaatcaa aaagtaaact aggaagatag ccacaggttt ctcaaagtat
    66901 agctttgagg ttgtaaataa aactgacgaa gtcagatcaa agtatagctt tgaggttgta
//
LOCUS       DAVBBO010000005        51676 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ST1
            SAMEA2066453-rid20184263.denovo.005, whole genome shotgun sequence.
ACCESSION   DAVBBO010000005 DAVBBO010000000
VERSION     DAVBBO010000005.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2066453
            Sequence Read Archive: ERR351777
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 51676)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 51676)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980402.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980402.1
            Genome Coverage       :: 176x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:17:33
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,141
            CDSs (total)                      :: 2,104
            Genes (coding)                    :: 1,953
            CDSs (with protein)               :: 1,953
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 16S)
            partial rRNAs                     :: 1 (23S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 151
            CDSs (without protein)            :: 151
            Pseudo Genes (ambiguous residues) :: 0 of 151
            Pseudo Genes (frameshifted)       :: 73 of 151
            Pseudo Genes (incomplete)         :: 76 of 151
            Pseudo Genes (internal stop)      :: 40 of 151
            Pseudo Genes (multiple problems)  :: 32 of 151
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..51676
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2066453-rid20184263.denovo.005"
                     /strain="ST1"
                     /db_xref="taxon:1313"
     gene            complement(54..362)
                     /locus_tag="VQU30_000305"
                     /pseudo
     CDS             complement(54..362)
                     /locus_tag="VQU30_000305"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000996568.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="GDP-mannose 4,6-dehydratase"
     gene            complement(604..900)
                     /locus_tag="VQU30_000306"
     CDS             complement(604..900)
                     /locus_tag="VQU30_000306"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000239014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2446487.1"
                     /translation="MVKINKICSIQGSSVENEDIVGSQNQYFWIIGGATDLYNSKEEI
                     GYSVSEVVHILSESLSVNCKESKTLKQIFETALLEVKDEIGLNSYELTEYSKMK"
     gene            complement(884..3043)
                     /gene="pfbA"
                     /locus_tag="VQU30_000307"
     CDS             complement(884..3043)
                     /gene="pfbA"
                     /locus_tag="VQU30_000307"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010976622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multi-ligand-binding adhesin PfbA"
                     /protein_id="HET2446488.1"
                     /translation="MLKIVKKLEVLMKYFVPNEVFSIRKLKVGTCSVLLAISILGSQG
                     ILSDEVVTSSSPMATKESSNAITNDLDNSPTVNQNRSAEMIASNSTTNGLDNSLSVNS
                     ISSNGTIRSNSQLDNRTVESTVISTNENKSYKEDVISDRIIKKEFEDTALSVKDYGAV
                     GDGIHDDRQAIQDAIDAAAQGLGGGNVYFPEGTYLVKEIVFLKSHTHLELNEKATILN
                     GINIKNHPSIVFMTGLFTDDGAQVEWGPTEDISYSGGTIDMNGALNEEGTKAKNLPLI
                     NSSGAFAIGNSNNVTIKNVTFKDSYQGHAIQIAGSKNVLVDNSRFLGQALPKTMKDGQ
                     IISKESIQIEPLTRKGFPYALNDDGKKSENVTIQNSYFGKSDKSGELVTAIGTHYQTL
                     STQNPSNIKILNNHFDNMMYAGVRFTGFTDVLIKGNRFDKKVKGESVHYRESGAALVN
                     AYSYKNTKDLLDLNKQVVIAENIFNIADPKTKAIRVAKDSAEYLGKVSDITVTKNVIN
                     NNSKETEQPNIELLRVSDNLVVSENSIFGGKEGIVIEDSKGKITVLNNQFYNLSGKYI
                     SFIKSNANGKESVIRDSDGNFNIVTENGLYKIVTNNLSDKNEKEKNKEEKQSNSNNVI
                     DSNQKNGEFNSSKDNRQMNDKIDNKQDNKTEEVNYKIVGDGRETENHINKSKEIVDVK
                     QKLPKTGSNKIMELFLTVTGIGLLLTLKGLKYYGKDK"
     gene            complement(4173..5399)
                     /locus_tag="VQU30_000308"
     CDS             complement(4173..5399)
                     /locus_tag="VQU30_000308"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001134527.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegT/DnrJ/EryC1/StrS aminotransferase family
                     protein"
                     /protein_id="HET2446489.1"
                     /translation="MPNYNIPFSPPDITEAEIAEVADTLRSGWITTGPKTKELERRLS
                     LYTQTPKTVCLNSATAALELILRVFEVGPGDEVIVPAITYTASCSVITHVGATPVMVD
                     IQADTFEMDYDLLEQAITEKTKVIIPVELAGIVCDYDRLFQVVEKKRDFFTASSKWQK
                     AFNRIVIVSDSAHALGSTYKGQPSGSIADFTSFSFHAVKNFTTAEGGSATWKANPVID
                     DEEMYKEFQILSLHGQTKDALAKMQLGSWEYDIVTPAYKCNMTDIMASLGLVQLDRYP
                     SLLQRRKDIVDRYDSGFAGSRIHPLAHKTETVESSRHLYITRVEGASLEERNLIIQEL
                     AKAGIASNVHYKPLPLLTAYKNLGFDMTNYPKAYAFFENEITLPLHTKLSDEEVDYII
                     ETFKTVSEKVLTLSKK"
     gene            complement(5442..6134)
                     /locus_tag="VQU30_000309"
     CDS             complement(5442..6134)
                     /locus_tag="VQU30_000309"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000922225.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar transferase"
                     /protein_id="HET2446490.1"
                     /translation="MLKWEDLPVEMKSSEVESYYQLVSKRKGSLIFKRCLDWVLALVL
                     LVLTSPIFLILSIWIKLDSKGPVIYKQERVTQYNRRFKIWKFRTMVTDADKKGNLVTS
                     ANDSRITKVGNFIRRVRLDELPQLVNVLKGEMSFVGTRPEVPRYTEQYSTEMMATLLL
                     QAGITSPASINYKDEDTIISQMTEKGLSVDQAYVEHVLPEKMRYNLAYLREFSFFGDI
                     KIMFQTVFKVLK"
     gene            complement(6320..8071)
                     /locus_tag="VQU30_000310"
     CDS             complement(6320..8071)
                     /locus_tag="VQU30_000310"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001180175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET2446491.1"
                     /translation="MQNKQEQWAVLKRLMSYLKPYRLLTFLALSFLLATTVIKSVIPL
                     VASHFIDQYLSNLNQLAVTVLLVYYGLYILQTVVQYVGNLLFARVSYSIVRDIRRDAF
                     ANMEKLGMSYFDKTPAGSIVSRLTNDTETISDMFSGILSSFISAVFIFLTTLYTMLVL
                     DFRLTALVLLFLPLIFLLVNLYRKKSVKIIEKTRSLLSDINSKLAENIEGIRIIQAFN
                     QEKRLQAEFDEINQEHLVYANRSVALDALFLRPAMSLLKLLGYAVLMAYFGYRGLSIG
                     ITAGTMYAFIQYINRLFDPLIEVTQNFSTLQTSMVSAGRVFALVDERTYEPLQENGQA
                     KVQEGNIRFEHVCFSYDGKHPILDDISFSVNKGETIAFVGHTGSGKSSIINVLMRFYE
                     FQSGRVLLDDVDIRDFSQEELRKNIGLVLQEPFLYHGTIKSNIAMYQEISDEQVQAAA
                     AFVDADSFIQELPQGYDSPVSERGSSFSTGQRQLLAFARTVASQPKILILDEATANID
                     SETESLVQASLAKMRQGRTTIAIAHRLSTIQDANCIYVLDKGRIIESGTHEELLALGG
                     TYHKMYSLQAGAMAYTL"
     gene            complement(8061..9806)
                     /locus_tag="VQU30_000311"
     CDS             complement(8061..9806)
                     /locus_tag="VQU30_000311"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000022567.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HET2446492.1"
                     /translation="MSIIQKLWWFFKLEKHRYLVGIVALVLVSVLNLIPPMVMGRVID
                     AITSGQLTQQDLLLSLFYLLLAAFGMYYLRYVWRMYILGTSYCLGQIMRSRLFKHFTK
                     MSPAFYQTYRTGDLMAHATNDINALTRLAGGGVMSAVDASITALVTLLTMLFSISWQM
                     TLVAILPLPFMAYATSRLGRKTHKAFGESQAAFSELNNKVQESVSGIKVTKSFGYQAD
                     ELKSFQAVNELTFQKNLQTMKYDSLFDPMVLLFVGSSYVLTLLVGSLMVQEGQITVGN
                     LVTFISYLDMLVWPLMAIGFLFNTTQRGKVSYQRIENLLSQESPVQDPEFPLDGIENG
                     RLEYAIDSFAFENEETLTDIHFSLAKGQTLGLVGQTGSGKTSLIKLLLREYDVDKGAI
                     YLNGHDIRDYRLTELRSLMGYVPQDQFLFATSILDNIRFGNPNLPLSEVEEATKLARV
                     YQDIVDMPQGFDTLIGEKGVSLSGGQKQRLAMSRAMILNPDILILDDSLSAVDAKTEY
                     AIIDNLKETRKDKTTIITAHRLSAVVHADFILVLQNGQIIERGRHEDLLAMDGWYAQT
                     YQSQQLEMKGEEDAE"
     gene            complement(10012..10308)
                     /locus_tag="VQU30_000312"
     CDS             complement(10012..10308)
                     /locus_tag="VQU30_000312"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001276342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF421 domain-containing protein"
                     /protein_id="HET2446493.1"
                     /translation="MSASDVALKLRSQGIFQMKQVKRAVQEQNGQLIVVQMGDENPKY
                     PVVTDGVIQVDVLESIGRSEEWLLDNLSKQGHDNVANIFIAEYDKGAVTVVTYE"
     gene            complement(10461..10917)
                     /locus_tag="VQU30_000313"
                     /pseudo
     CDS             complement(10461..10917)
                     /locus_tag="VQU30_000313"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730499.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3290 family protein"
     gene            11051..11878
                     /gene="xth"
                     /locus_tag="VQU30_000314"
     CDS             11051..11878
                     /gene="xth"
                     /locus_tag="VQU30_000314"
                     /EC_number="3.1.11.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006596696.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease III"
                     /protein_id="HET2446494.1"
                     /translation="MKLISWNIDSLNAALTSDSARAKLSQEVLQTLVAENADIIAIQE
                     TKLSAKGPTKKHVEILEELFPGYENTWRSSQEPARKGYAGTMFLYKKELTPTISFPEI
                     GAPSTMDLEGRIITLEFDAFFVTQVYTPNAGDGLKRLEERQVWDVKYAEYLAELDKEK
                     PVLATGDYNVAHNEIDLANPASNRRSPGFTDEERAGFTNLLATGFTDTFRHVHGDVPE
                     RYTWWAQRSKTSKINNTGWRIDYWLTSNRIADKVTKSDMIDSGARQDHTPIVLEIDL"
     gene            11890..12033
                     /locus_tag="VQU30_000315"
     CDS             11890..12033
                     /locus_tag="VQU30_000315"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glyoxalase"
                     /protein_id="HET2446495.1"
                     /translation="MDYNAVIPEFLVSNIEQSRSFYCGLLGFRIEYQRSEENFLFLLK
                     SVN"
     gene            12033..12272
                     /locus_tag="VQU30_000316"
     CDS             12033..12272
                     /locus_tag="VQU30_000316"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844973.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glyoxalase"
                     /protein_id="HET2446496.1"
                     /translation="MLEEGTKDQLAELTYPFGRGVNLSFGIKDVPKLYQKVMEANYPI
                     YRPLTKRKFRVSDPYIYPHKFAVLDPDGYFLRFSE"
     regulatory      12656..12751
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00167"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="purine riboswitch; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="guanine and/or adenine"
                     /db_xref="RFAM:RF00167"
     gene            13151..13732
                     /locus_tag="VQU30_000317"
     CDS             13151..13732
                     /locus_tag="VQU30_000317"
                     /EC_number="2.4.2.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000770427.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="xanthine phosphoribosyltransferase"
                     /protein_id="HET2446497.1"
                     /translation="MKLLEERILKDGHILGDNILKVDSFLTHQVDFSLMREIGKVFAE
                     KFAAAGITKVVTIEASGIAPAVFTAEALNVPMIFAKKAKNITMNEGILTAQVYSFTKQ
                     VTSTVSIAGKFLSPEDKVLIIDDFLANGQAAKGLIQIIEQAGATVQAIGIVIEKSFQD
                     GRDLLEKAGYPVLSLARLDRFENGQVVFKEADL"
     gene            13732..14994
                     /locus_tag="VQU30_000318"
     CDS             13732..14994
                     /locus_tag="VQU30_000318"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001194492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="purine permease"
                     /protein_id="HET2446498.1"
                     /translation="MQTQEKHSQAAVLGLQHLLAMYSGSILVPIMIATALGYSAEQLT
                     YLISTDIFMCGVATFLQLQLNKYFGIGLPVVLGVAFQSVAPLIMIGQSHGSGAMFGAL
                     IASGIYVVLVSGIFSKVANLFPSIVTGSVITTIGLTLIPVAIGNMGNNVPEPTGQSLL
                     LSAITVLIILLINIFTKGFIKSISILIGLVVGTAIAATMGLVDFSPVAVAPLVHVPTP
                     LYFGMPTFEISSIVMMCIIATVSMVESTGVYLALSDITKDPIDSTRLRNGYRAEGLAV
                     LLGGIFNTFPYTGFSQNVGLVKLSGIKKRLPIYYAAGFLVLLGLLPKFGALAQIIPSS
                     VLGGAMLVMFGFVSIQGMQILARVDFANNEHNFLIAAVSIAAGVGLNNSNLFVSMPTA
                     FQMFFSNGIVVASLLAIVLNAVLNHKKK"
     gene            complement(15081..15947)
                     /locus_tag="VQU30_000319"
     CDS             complement(15081..15947)
                     /locus_tag="VQU30_000319"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000815109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II restriction endonuclease"
                     /protein_id="HET2446499.1"
                     /translation="MKQTRNFDEWLSTMTDTVADWTYYTDFPKVYKNVSSIKVALNIM
                     NSLIGSKNIQEDFLDLYQNYPEILKVVPLLIAKRLRDTIIVKDPIKDFYFDFSKRNYS
                     IEEYTMFLEKSGIFDLLQNHLVSNLVDYVTGVEVGMDTNGRKNRTGDAMENIVQSYLE
                     AEGYILGENLFKEIEQNEIEEIFSVDLSAITNDGNTVKRFDFVIKNEQVLYLIEVNFY
                     SGSGSKLNETARSYKMIAEEIKAIPNVEFMWITDGQGWYKAKNNLRETFDILPFLYNI
                     NDLEHNILKNLK"
     gene            complement(15934..16704)
                     /locus_tag="VQU30_000320"
     CDS             complement(15934..16704)
                     /locus_tag="VQU30_000320"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001810592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific DNA-methyltransferase"
                     /protein_id="HET2446500.1"
                     /translation="MTKPYYNKNKMILVHSDTFKFLSKMKPESMDMIFADPPYFLSNG
                     GISNSGGQVVSVDKGDWDKISSFEEKHEFNRKWIRLAKEVLKPNGTVWISGSLHNIYS
                     VGMALEQEGFKILNNITWQKTNPAPNLSCRYFTHSTETILWARKNDKKARHYYNYDLM
                     KELNDGKQMKDVWTGSLTKKVEKWAGKHPTQKPEYLLERIILASTKEGDYILDPFVGS
                     GTTGVVAKRLGRRFIGIDAEKEYLKIARKRLEAENETN"
     gene            complement(16730..17584)
                     /locus_tag="VQU30_000321"
     CDS             complement(16730..17584)
                     /locus_tag="VQU30_000321"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012972462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA adenine methylase"
                     /protein_id="HET2446501.1"
                     /translation="MKIKEIKKVTLQPFTKWTGGKRQLLPVIRELMPKTYNRYFEPFV
                     GGGALFFDLAPKDAVINDFNAELINCYQQIKDNPQELIEILKVHQEYNSKEYYLDLRS
                     ADRDERIDMMSEVQRAARILYMLRVNFNGLYRVNSKNQFNVPYGRYKNPKIVDEELIS
                     AISVYLNNNQLEIKVGDFEKAIVDVRTGDFVYFDPPYIPLSETSAFTSYTHEGFSFAD
                     QVRLRDAFKRLSDTGAYVMLSNSSSALVEELYKDFNIHYVEATRTNGAKSSSRGKISE
                     IIVTNYEK"
     gene            complement(17741..18145)
                     /locus_tag="VQU30_000322"
     CDS             complement(17741..18145)
                     /locus_tag="VQU30_000322"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000651202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PaaI family thioesterase"
                     /protein_id="HET2446502.1"
                     /translation="MKDFHFDAISAFENYEIEKMRDGHVVVTTKVVNSSLNYYGNAHG
                     GYLFTLCDQISGLVVISLGLDGVTLQSSINYLKAGKLDDVLTIKGECVHQGRTTCVMD
                     VDITNQEGRNVCKATFTMFVTGQRSEERRVRI"
     gene            complement(18215..19696)
                     /locus_tag="VQU30_000323"
     CDS             complement(18215..19696)
                     /locus_tag="VQU30_000323"
                     /EC_number="2.7.7.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001861845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose--hexose-1-phosphate
                     uridylyltransferase"
                     /protein_id="HET2446503.1"
                     /translation="MTLVDKFVTHVISESSFEEMDRIYLTNRVLARVGEGVLEVETNL
                     DKLIDLKDQLVEEAVRLETIEDSQTAREILGTELMDLVTPCPSQVNRDFWEAYAYSPE
                     QAIEDFYQLSQKNDYIKLKAIAKNIVYRVPSDYGELEITINLSKPEKDPKEIAVAKLV
                     QASNYPQCQLCLENEGYHGRVNHPARSNHRIIRFEMVGQEWGFQYSPYAYFNEHCIFL
                     DGQHRPMAISRQSFERLLAIVEQFPGYFAGSNADLPIVGGSILTHDHYQGGRHVFPME
                     LAPLQKTFRFAGFEQVKAGIIKWPMSVLRLTSDSKEDLINLADKIFQEWRQYSDSSVQ
                     ILAETDGTPHHTITPIARKRDGQFELDLVLRDNQTSADHPDGIYHPHKDVQHIKKENI
                     GLIEVMGLAILPPRLKEEVEQVASYLVGEAVTVADYHQEWADQLKSQHPDLTDKEKAL
                     AIVKDSVGAIFARVLEDAGVYKQTEQGQTAFMRFVEHVGILLD"
     gene            complement(19715..20893)
                     /locus_tag="VQU30_000324"
     CDS             complement(19715..20893)
                     /locus_tag="VQU30_000324"
                     /EC_number="2.7.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000189889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactokinase"
                     /protein_id="HET2446504.1"
                     /translation="MAQHLTTEALRKDFLAVFGQEADQTFFSPGRINLIGEHTDYNGG
                     HVFPAAISLGTYGAARKRDDQVLRFYSANFEDKGIIEVPLADLKFEKEHNWTNYPKGV
                     LHFLQEAGHVIDKGFDFYVYGNIPNGAGLSSSASLELLTGVVAEHLFDLKLERLDLVK
                     IGKQTENNFIGVNSGIMDQFAIGMGADQRAIYLDTNTLEYDLVPLDLKDNVVVIMNTN
                     KRRELADSKYNERRAECEKAVEELQVALDIQTLGELDEWAVDQYSYLIKDENRLKRAR
                     HAVFENQRTLKAQAALQAGDLETFGRLMNASHVSLEHDYEVTGLELDTLVHTAWAQEG
                     VLGARMTGAGFGGCAIALVQKDTVEAFKEAVGKHYEEVVGYAPSFYIAEVAGGTRVLD
                     "
     gene            21058..22065
                     /gene="galR"
                     /locus_tag="VQU30_000325"
     CDS             21058..22065
                     /gene="galR"
                     /locus_tag="VQU30_000325"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000212522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding transcriptional regulator GalR"
                     /protein_id="HET2446505.1"
                     /translation="MATLKDIAQLASVSIATVSRVLNRDQSLSVTEETRHRILTVAEE
                     LGYTKHLKTGESHKPKQKIAIIQWVSEQGELDDLYYYQIRLGIEKRAQELDYDILRYF
                     NDHPFTLSEEVIGILCIGKFSRAQISAFEEYQKPLVFLDSDTLSLGHTCIITDFYTAM
                     KQVVDYFLSQGMDRIGILTGLEETTDQEEIIQDKRLENFRNYSQAKGIYHDELVFQGN
                     FTAQSGYDLMKEAIQNLGDQLPPAFFAASDSLAIGALRALQEAGISLPDRVSLISFND
                     TSLTKQVYPPLSSITVYTEEMGRAGMDILNKEVLHDRKIPSLTMLGTRLTLRESTLNQ
                     E"
     gene            complement(22111..23148)
                     /locus_tag="VQU30_000326"
     CDS             complement(22111..23148)
                     /locus_tag="VQU30_000326"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000833740.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alcohol dehydrogenase catalytic
                     domain-containing protein"
                     /protein_id="HET2446506.1"
                     /translation="MKSAVYTKAGQVGLASIERPQIIEADDVIIRVVRACVCGSDLWR
                     YRNPETKAGHKNSGHEAIGIVEEAVEAITTVKPGDFVIVPFTHGCGECDACLAGFDGS
                     CDNHIGNNLGGDFQAEYIRFHYANWALVKIPGQPSDYTEGMLQSLLTLADVMPTGYHA
                     ARVANVQKGDKVVVIGDGAVGQCAVIAAKMRGASQIILMSRHEDRQKMAMESGATAVV
                     AERGQEGITKVREILGGGADAALECVGTEAAIEQALGVLHNGGRMGFVGVPHYNNRAL
                     GSTFMQNISVAGGAASATTYDKQFLLKAVLDGDINPGRVFTSSYKLEDIDQAYKDMDE
                     RKTIKSMIVIE"
     gene            complement(23149..23502)
                     /locus_tag="VQU30_000327"
     CDS             complement(23149..23502)
                     /locus_tag="VQU30_000327"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HET2446507.1"
                     /translation="MNIKSASDLLGISADTIRYYERVGLVPPITRTATGIRDFQDQDI
                     EALEFIKCFRSAGVSVDSLVDYMSLYQKGDETREERLGILEEEKQKLEERLSQLQTAL
                     NRLNLKIKLYKEGKF"
     gene            complement(23746..24636)
                     /locus_tag="VQU30_000328"
     CDS             complement(23746..24636)
                     /locus_tag="VQU30_000328"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000645104.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation transporter"
                     /protein_id="HET2446508.1"
                     /translation="MKAKYAVWVAFFLNLTYAIVEFIAGGVFGSSAVLADSVHDLGDA
                     IAIGISAFLETISNREEDNQYTLGYKRFSLLGALVTAVILVTGSVLVILENVTKILHP
                     QPVNDEGILWLGIIAITINLLASLVVGKGKTKNESILSLHFLEDTLGWVAVILMAIVL
                     RFTDWYILDPLLSLVISFFILSKALPRFWSTLKIFLDAVPEGLDIKQVKSGLERLDNV
                     ASLNQLNLWTMDALEKNAIVHVCLKEMEHMETCKESIRIFLKDCGFQNITIEIDADLE
                     THQTHKRKVCDLERSYEHQH"
     gene            24769..25305
                     /locus_tag="VQU30_000329"
     CDS             24769..25305
                     /locus_tag="VQU30_000329"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HET2446509.1"
                     /translation="MTNIDRRISKTKKAIYQAFIQLLNAKGYEATTVQDIIDLADVGR
                     STFYCHYESKELLLDQLCRYLFHHLFEREQAISTEDYLAHLFLHFHKNQDHITSLLFS
                     KNDYFLRQLHKELEHHVYSVLADNLKEAHPNLPTSYLQHLVMSNFIETLTWWLKKGQD
                     FTDQEVVQFYLDLLIPKN"
     gene            complement(25472..26278)
                     /locus_tag="VQU30_000330"
     CDS             complement(25472..26278)
                     /locus_tag="VQU30_000330"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863945.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinamide riboside transporter PnuC"
                     /protein_id="HET2446510.1"
                     /translation="MHTYLQKKIENIKTTLGEMSGGYRRMVAAMADLGFSGTMKAIWD
                     DLFAHRSFAQWIYLLVLGSFPLWLELVYEHRIVDWIGMICSLTGIICVIFVSEGRASN
                     YLFGLINSVIYLILALQKGFYGEVLTTLYFTVMQPIGLLVWIYQAQFKKEKQEFVARK
                     LDGKGWTKYLSISVLWWLAFGFIYQSIGANRPYRDSITDATNGVGQILMTAVYREQWI
                     FWAATNVFSIYLWWGESLQIQGKYLIYLINSLVGWYQWSKAAKQNTDLLN"
     gene            complement(26623..28143)
                     /locus_tag="VQU30_000331"
     CDS             complement(26623..28143)
                     /locus_tag="VQU30_000331"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007521043.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease/substrate-binding
                     protein"
                     /protein_id="HET2446511.1"
                     /translation="MTNLIATFQDRFSDWLTALSQHLQLSLLTLLLAILLAIPLAVFL
                     RYHEKLADWVLQIAGIFQTIPSLALLGLFIPLMGIGTLPALTALVIYAIFPILQNTIT
                     GLKGIDPNLQEAGIAFGMTRWERLKKFEIPLAMPVIMSGIRTAAVLIIGTATLAALIG
                     AGGLGSFILLGIDRNNASLILIGALSSAVLAIAFNFLLKVMEKAKLRTIFSGFALVAL
                     LLGLSYSPALLVQKEKENLVIAGKIGPEPEILANMYKLLIEENTSMTATVKPNFGKTS
                     FLYEALKKGDIDIYPEFTGTVTESLLQPSPKVSHEPEQVYQVARDGIAKQDHLAYLKP
                     MSYQNTYAVAVPKKIAQEYGLKTISDLKKVEGQLKAGFTLEFNDREDGNKGLQSMYGL
                     NLNVATMEPALRYQAIQSGDIQITDAYSTDAELERYDLQVLEDDKQLFPPYQGAPLMK
                     EALLKKHPELERVLNTLAGKITESQMSQLNYQVGVEGKSAKQVAKEFLQEQGLLKK"
     gene            complement(28136..28864)
                     /locus_tag="VQU30_000332"
     CDS             complement(28136..28864)
                     /locus_tag="VQU30_000332"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730520.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET2446512.1"
                     /translation="MIEYKNVALRYTEKDVLRDVNLQIEDGEFMVLVGPSGSGKTTML
                     KMINRLLEPTDGNIYMDGKRIKDYDERELRLSTGYVLQAIALFPNLTVAENIALIPEM
                     KGWSKEEITKKTEELLAKVGLPVAEYGHRLPSELSGGEQQRVGIVRAMIGQPKIFLMD
                     EPFSALDAISRKQLQVLTKELHKEFGMTTIFVTHDTDEALKLADRIAVLQDGEIRQVA
                     NPETILKAPATDFVADLFGGSVHD"
     gene            complement(28879..29643)
                     /locus_tag="VQU30_000333"
     CDS             complement(28879..29643)
                     /locus_tag="VQU30_000333"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000043863.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nuclear transport factor 2 family protein"
                     /protein_id="HET2446513.1"
                     /translation="MSQQVKNAHNLYIHAIQDGRVAEAQAQSVGDTYIQHSTGVPDGK
                     EGFAAFFADFFERHPERQIKIVRTIEDGNLVFVHVHQYLNGGEAQWVTTDTFRADENG
                     RIVEHWDVVDYYRTPENDQLDQIFGDFEIKDLDKKAENKKLVRRFLTEIFQNGELEQW
                     SDYVADDLIQHNHDIGQGSAAYKNYVAEYSVTFDFVFQLLGQGNYVVSYGQTQIDGVA
                     YAQYDIFRLENGKIVEHWDNKEVMPKVEDLTNRGKF"
     gene            complement(29647..30090)
                     /locus_tag="VQU30_000334"
     CDS             complement(29647..30090)
                     /locus_tag="VQU30_000334"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000655204.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HET2446514.1"
                     /translation="MKDSHLLAHHIRLLNGRIFQKLLSQDPEALYRGEQGKILAVLWN
                     SETGCATATDIALATGLANNTLTTMIKKLEEQKLVIVSPCGKDKRKKYLVLTELGKFQ
                     KEVGHRVSQKLDTIFYKGFSEEEIHQFEGFQERILANLKEKGNEV"
     gene            complement(30772..31068)
                     /locus_tag="VQU30_000335"
     CDS             complement(30772..31068)
                     /locus_tag="VQU30_000335"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000230158.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin immunity protein"
                     /protein_id="HET2446515.1"
                     /translation="MAEPNLESLIKDLYNHARHDLSEDLVAALLETAKKLPTTNEQLQ
                     AVRLSGLVNRELLLNPKHPAPELLNLARFIKREEAKYRGTATSALMYEELFKML"
     gene            complement(31090..32154)
                     /gene="pepA"
                     /locus_tag="VQU30_000336"
     CDS             complement(31090..32154)
                     /gene="pepA"
                     /locus_tag="VQU30_000336"
                     /EC_number="3.4.11.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519237.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamyl aminopeptidase"
                     /protein_id="HET2446516.1"
                     /translation="MTTLFSKIKEVTELAAVSGHEAPVRAYLREKLTPHVDEVVTDGL
                     GGIFGIKHSEAVDAPRVLVASHMDEVGFMVSEIKPDGTFRVVEIGGWNPMVVSSQRFK
                     LLTRDGHEIPVISGSVPPHLTRGKGGPTMPAIADIVFDGGFADKAEAESFGIRPGDTI
                     VPDSSAILTANEKNIISKAWDNRYGVLMVSELAEALSGQKLGNELYLGSNVQEEVGLR
                     GAHTSTTKFDPEVFLAVDCSPAGDVYGGQGKIGDGTLIRFYDPGHLLLPGMKDFLLTT
                     AEEAGIKYQYYCGKGGTDAGAAHLKNGGVPSTTIGVCARYIHSHQTLYAMDDFLEAQA
                     FLQALVKKLDRSTVDLIKHY"
     gene            32555..33256
                     /gene="galE"
                     /locus_tag="VQU30_000337"
     CDS             32555..33256
                     /gene="galE"
                     /locus_tag="VQU30_000337"
                     /EC_number="5.1.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000167854.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose 4-epimerase GalE"
                     /protein_id="HET2446517.1"
                     /translation="MTKTILVTGGTSYIGSHTVKALLNAGYKVHVLDNLSTGNRAAVD
                     SRASFKELDVYDASALKAYLEENQIDAVLHCAGEIVVSESIENPSKYFTANVAGMNQV
                     LKVLSEVGIQKIMFSSTASLYGNNCIDKPVTEDTLLDPVNPYAETKLMGERMIYWMAN
                     RYDWKYVIFRYFNVAGAEMDASNGLRVKNPTHIIPNINKTALGQNDSLKIFGDDYDTR
                     DGSCIRDYIYVLDLA"
     gene            33679..34638
                     /locus_tag="VQU30_000338"
     CDS             33679..34638
                     /locus_tag="VQU30_000338"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000777236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HET2446518.1"
                     /translation="MKLSHYLIGLLLLLVFLSISIGTSDFSWGKLFDFDQQTWLLFQE
                     SRLPRTISILLTASSMSMAGLLMQTITQNQFAAPSTVGTTEAAKLGMVLSLFVFPSAS
                     LTQKMLFAFVSSIVFTLFFLAFMTIFTVKERWMLPLIGIIYSGIIGSVTEVIAYRFNL
                     VQSMTAWTQGSFSMIQTHQYEWLFLGLIILITVWKLSQTFTIMNLGKEISESLGISYS
                     LLEKLALFLVALTTSVTMITVGGLPFLGVIVPNLVRKRYGDNLSQTKLMVALVGANLV
                     LACDILSRVLIRPYELSVSLLLGIIGSLGFILLLWRGGRKDAD"
     gene            34628..35584
                     /locus_tag="VQU30_000339"
     CDS             34628..35584
                     /locus_tag="VQU30_000339"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001193667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron chelate uptake ABC transporter family
                     permease subunit"
                     /protein_id="HET2446519.1"
                     /translation="MQTKSKHTKLFWILIILAIGACLLYFWPITHLSAFAWKLRSQKI
                     IVYLLVAIATGISTISFQTLTENRFLTPSILGIESFYVLLQTLLLVFESKFLQLGKSP
                     ILEFLVLLLVQSLFFLTLQGYLKTLMKQDLVFILLICLALRSLFRNISTFLQVLMDPN
                     EYDKLQNSLFASFQHLNTSILAIGSLIILALTIFFFRKAVVLDVLHLQRETAQILGLD
                     VEKEQKELLWGIVLLTSTATALVGPMAFFGFMLANLTYLIVKDYQHKLLFIVAILVGF
                     ISLTLGQALIERVFALEIRISMIIESVGGFLFFILLYRRSRQ"
     gene            35581..36333
                     /locus_tag="VQU30_000340"
     CDS             35581..36333
                     /locus_tag="VQU30_000340"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000764290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET2446520.1"
                     /translation="MKLENIDKSIQKQDILQGISLEVSPQKLTAFIGPNGAGKSTLLS
                     IMSRLTKKDQGVLSIKGREIESWNSQELAQELTILKQKINYQAKLTVEELVSFGRFPY
                     SRGRLRSEDWEKIRETLNYLELTNLKDRYINSLSGGQLQRVFIAMVLAQDTDFILLDE
                     PLNNLDIKQSVSMMQILRRLVEELGKTIIIVLHDINMASQYADEIVAFKDGQVFSKGS
                     TDQIMQADLLSQLYEIPITLADINDKKICIYS"
     gene            36429..37394
                     /locus_tag="VQU30_000341"
     CDS             36429..37394
                     /locus_tag="VQU30_000341"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000858258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="siderophore ABC transporter substrate-binding
                     protein"
                     /protein_id="HET2446521.1"
                     /translation="MKTSLKLYFTALVASFLLLLGACSTNSSTSQTETSSSAPTEVTI
                     KSSLDEVKLSKVPEKIVTFDLGAADTIRALGFEKNIVGMPTKTVPTYLKDLVGTVKNV
                     GSMKEPDLEAIAALEPDLIIASPRTQKFVDKFKEIAPTVLFQASKDDYWTSTKANIES
                     LASAFGETGTQKAKEELAKLDKSIQEVATKNESSDKKALAILLNEGKMAAFGAKSRFS
                     FLYQTLKFKPTDTKFEDSRHGQEVSFESVKEINPAILFVINRTLAIGGDNSSNDGVLE
                     NALIAETPAAKNGKIIQLTPDLWYLSGGGLESTKLMIEDIQKALK"
     gene            complement(37619..37861)
                     /gene="yidD"
                     /locus_tag="VQU30_000342"
     CDS             complement(37619..37861)
                     /gene="yidD"
                     /locus_tag="VQU30_000342"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein insertion efficiency factor
                     YidD"
                     /protein_id="HET2446522.1"
                     /translation="MKRILIAPVRFYQRFISPVFPPSCRFELTCSNYMIQAIEKHGFK
                     GVLMGLARILRCHPWSKTGKDPVPDHFSLKRNQEGE"
     gene            complement(37861..38583)
                     /locus_tag="VQU30_000343"
     CDS             complement(37861..38583)
                     /locus_tag="VQU30_000343"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006150169.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA pseudouridine synthase"
                     /protein_id="HET2446523.1"
                     /translation="MRINKYIAHAGVASRRKAEELIKQGLVTVNGQVVRELATTIKSG
                     DKVEVEGQPIYNEEKVYYLLNKPRGVISSVTDDKGRKTVVDLLPNVKERIYPVGRLDW
                     DTSGVLILTNDGDFTDEMIHPRNEIDKVYVARVKGVANKDNLRPLTRGLEIDGKKTKP
                     AVYEILKVDPVKNRSVVQLTIHEGRNHQVKKMFEAVGLQVDKLSRTRFGHLDLTGLRP
                     GESRRLNKKEISQLHTMAVTKK"
     gene            complement(38570..39139)
                     /locus_tag="VQU30_000344"
     CDS             complement(38570..39139)
                     /locus_tag="VQU30_000344"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000105309.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="segregation/condensation protein B"
                     /protein_id="HET2446524.1"
                     /translation="MSTLAKIEALLFVAGEDGIRVRQLAELLSLPPTGIQQSLGKLAQ
                     KYEKDPDSSLALIETSGAYRLVTKSQFAEILKEYSKAPINQSLSRAALETLSIIAYKQ
                     PITRIEIDAIRGVNSSGALAKLQAFDLIKEDGKKEVLGRPNLYVTTDYFLDYMGINHL
                     EELPVIDELEIQAQESQLFGERIEEDENQ"
     gene            complement(39158..39886)
                     /locus_tag="VQU30_000345"
     CDS             complement(39158..39886)
                     /locus_tag="VQU30_000345"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000351912.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="segregation/condensation protein A"
                     /protein_id="HET2446525.1"
                     /translation="MDIKLKDFEGPLDLLLHLVSKYQMDIYDVPITEVIEQYLAYVST
                     LQAMRLEVTGEYMVMASQLMLIKSRKLLPKVAEVTDLGDDLEQDLLSQIEEYRKFKLL
                     GEHLEAKHQERAQYYSKAPTELIYEDAELVHDKTTIDLFLAFSNILAKKKEEFAQNHT
                     TILRDEYKIEDMMIIVKESLIGRDQLRLQDLFKEAQNVQEVITLFLATLELIKTQELI
                     LVQEESFGDIYLMEKKEESQVPQS"
     gene            complement(39886..40626)
                     /gene="xerD"
                     /locus_tag="VQU30_000346"
     CDS             complement(39886..40626)
                     /gene="xerD"
                     /locus_tag="VQU30_000346"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004245562.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific tyrosine recombinase XerD"
                     /protein_id="HET2446526.1"
                     /translation="MPMRDRISAFLEEKQGLSVNSKQSYKYDLEQFLDMVGERISETS
                     LKIYQAQLANLKISAQKRKISACNQFLYFLYQKGEVDSFYRLELAKQAEKKTEKPEIL
                     YLDSFWQESDHPEGRLLALLILEMGLLPSEILAIKVADINLDFQVLRISKASQQRIVT
                     IPTALLSELEPLMGQTYLFERGEKPYSRQWAFRQLESFVKEKGFPSLSAQVLREQFIL
                     RQIENKVDLYEIAKKLGLKTVLTLEKYR"
     gene            complement(40617..41078)
                     /locus_tag="VQU30_000347"
     CDS             complement(40617..41078)
                     /locus_tag="VQU30_000347"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000560721.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CBS domain-containing protein"
                     /protein_id="HET2446527.1"
                     /translation="MIAKEFETFLLGQEETFLTPAKNLAVLIDTHNADHATLLLSQMT
                     YTRVPVVTDEKQFVGTIGLRDIMAYQMEHDLSQEIMADTDIVHMTKTDVAVVSPDFTI
                     TEVLHKLVDESFLPVVDAEGIFQGIITRKSILKAVNALLHDFSKEYEIRCQ"
     gene            complement(41075..41596)
                     /locus_tag="VQU30_000348"
     CDS             complement(41075..41596)
                     /locus_tag="VQU30_000348"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001118598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase"
                     /protein_id="HET2446528.1"
                     /translation="MAKQTIIVMSDSHGDSLIVEEVRDRYVGKVDAVFHNGDSELRPD
                     SPLWEGIRVVKGNMDFYAGYPERLVTELGSTKIIQTHGHLFDINFNFQKLDYWAQEEE
                     AAICLYGHLHVPSAWLEGKILFLNPGSISQPRGTIRECLYARVEIDDSYFKVDFLTRD
                     HEVYPGLSKEFSR"
     gene            complement(41572..42543)
                     /locus_tag="VQU30_000349"
     CDS             complement(41572..42543)
                     /locus_tag="VQU30_000349"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000182414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside-triphosphate diphosphatase"
                     /protein_id="HET2446529.1"
                     /translation="MTNKIYEYKDDQDWYVGSYSIFGGVNSLSDYKTDFPLFEFSKIF
                     GDEEYGFPLSVTVLRYGSTYRLFSFVVDMLNQEMGRNLEVIQRHGALLLVENGQLLYV
                     ELPKEGVNVHDFFETSKVRETLLIATRNEGKTKEFRAIFDKLGYDVENLNDYPDLPEV
                     AETGMTFEENARLKAETISQLTGKMVLADDSGLKVDVLGGLPGVWSARFAGVGATDRE
                     NNAKLLHELAMVFELKDRSAQFHTTLVVASPNKESLVVEADWSGYINFEPKGENGFGY
                     DPLFLVGETGKSSAELTLEEKNSQSHRALAVKKLLEVFPSWQSKPSL"
     gene            complement(42540..43334)
                     /gene="racE"
                     /locus_tag="VQU30_000350"
     CDS             complement(42540..43334)
                     /gene="racE"
                     /locus_tag="VQU30_000350"
                     /EC_number="5.1.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000370386.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate racemase"
                     /protein_id="HET2446530.1"
                     /translation="MDNRPIGFLDSGVGGLTVVRELMRQLPHEEIVYIGDSARAPYGP
                     RPAEQIREYTWQLVNFLLTKDVKMIVIACNTATAVVWEEIKAQLDIPVLGVILPGASA
                     AIKSSQGGKIGVIGTPMTVQSDIYRQKIHDLDPDLQVESLACPKFAPLVESGALSTSV
                     TKKVVYETLRPLVGKVDSLILGCTHYPLLRPIIQNVMGPKVQLIDSGAECVRDISVLL
                     NYFEINRGRDAGPLHHRFYTTASSQSFAQIGEEWLEKEIYVEHVEL"
     gene            complement(43541..43789)
                     /locus_tag="VQU30_000351"
     CDS             complement(43541..43789)
                     /locus_tag="VQU30_000351"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000364981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YneF family protein"
                     /protein_id="HET2446531.1"
                     /translation="MDLLLAIVLIVLAFLGGALGGMYLVRKQIEKEFADNPRLNAEAV
                     RTLLSANGQKPSEAKVQQVYHQIIRQQKAALANNKKKK"
     gene            complement(43931..45556)
                     /gene="treC"
                     /locus_tag="VQU30_000352"
     CDS             complement(43931..45556)
                     /gene="treC"
                     /locus_tag="VQU30_000352"
                     /EC_number="3.2.1.93"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000171230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha,alpha-phosphotrehalase"
                     /protein_id="HET2446532.1"
                     /translation="MTLDKGKVVYQIYPKSYKDTTGNGIGDFRGIIGKIPYLAKLGVD
                     MVWLNPFYPSPQRDNGYDISDYMAVDPLFGDMADFEEMVCIGKEHKIDFMLDMVLNHC
                     STEHEWFQKALAGDKYYQDFFFIQDQPTDWQSKFGGSAWAPFGDTGKYYLHLFDETQA
                     DLNWRNPNVRKELFKVVNFWRDKGVKGFRFDVINLIGKDEVSVDCPENEGKPAYTDKP
                     IVHNYLRMMNQATFGSDDSFMTVGEMSSTTMENCVLYSSPDRQELSMTFNFHHLKVDY
                     KDGQKWTLAPFDFEELKSLYHSWGKEMSDKDGWSALFWNNHDQPRALNRFVDIQNFRK
                     EGATMLAASIHLSRGTPYIYMGEEIGMIDPDYDSMADYVDVESLNAYQMLLEEGKSQQ
                     EAFQIIQAKSRDNSRIPMQWDASENAGFSTGTPWLKAGKSYKDINVENEIQGPIFTFY
                     QDLIRLRKEMPIISEGSYKPAFEDSKQVYAFERQFEDQKLLVLNNFYAKEVEIDLPAV
                     YQNGQILISNYEDAEVSEKILLKPYQTLAIYVN"
     gene            complement(45734..47701)
                     /gene="treP"
                     /locus_tag="VQU30_000353"
     CDS             complement(45734..47701)
                     /gene="treP"
                     /locus_tag="VQU30_000353"
                     /EC_number="2.7.1.201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system trehalose-specific EIIBC component"
                     /protein_id="HET2446533.1"
                     /translation="MGKFEQEAKDLLQAIGGKENVTAVTHCATRMRFVLGNDKKANVK
                     AIESIPAVKGTFTNAGQFQVIIGNDVPIFYNDFTAVSGIEGVSKEAAKSAAKSNQNVV
                     QRVMTTLAEIFTPIIPALIVGGLILGFRNVLEGVHWSMLDGKTITESSQFWAGVNHFL
                     WLPGEAIFQFLPVGITWSVSRKMGTSQILGIVLGICLVSPQLLNAYAVASTPAADIAA
                     NWVWNFGYFTVNRIGYQAQVIPALLAGLSLSYLEIFWRKHIPEVISMIFVPFLSLIPA
                     LILAHTVLGPIGWTIGQGLSSVVLAGLTGPVKWLFGAIFGALYAPFVITGLHHMTNAI
                     DTQLIADAGGTALWPMIALSNIAQGSAVFAYYFMHRHDEREAQVSLPATISAYLGVTE
                     PALFGVNVKYIYPFVAGMTGSALAGMLSVTFNVTAASIGIGGLPGILSIQPQYMLPFA
                     GTMLVAIVVPMLLTFFFRKAGLFTKTEGDTNLQAEFVAQEEAEFVNHEPVELTSVEII
                     SPLTGQVKELSQATDPIFASGVMGQGLVIEPSQGELTSPVNGTVTVLFPTKHAIGIVS
                     DEGVELLIHIGMDTVGLDGKGFESLVVQGDHVTVGQQLIRFDMDVIKAAGLVTETPVI
                     ITNQDAYTATIPGTYPTTIQAGASLMVATRI"
     gene            47886..48596
                     /gene="treR"
                     /locus_tag="VQU30_000354"
     CDS             47886..48596
                     /gene="treR"
                     /locus_tag="VQU30_000354"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001865045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trehalose operon repressor"
                     /protein_id="HET2446534.1"
                     /translation="MKKYQQLFKQIQETIQNETYAVGDFLPSEHDLMEQYQVSRDTVR
                     KALSLLQEEGLIKKIRGQGSQVVKEETVNFPVSNLTSYQELVKELGLRSKTNVVSLDK
                     IIIDKKSSLITGFPEFRMVWKVVRQRVVDDLVSVLDTDYLDMELIPNLTRQIAEQSIY
                     SYIENGLKLLIDYAQKEITIDHSSDRDKILMDIGKDPYVVSIKSKVYLQDGRQFQFTE
                     SRHKLEKFRFVDFAKRKK"
     gene            complement(48629..49432)
                     /locus_tag="VQU30_000355"
     CDS             complement(48629..49432)
                     /locus_tag="VQU30_000355"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000157668.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HET2446535.1"
                     /translation="MASLLTLENIHKTFEAGTVNENHVLKGLDLEVEEGDFISVIGGN
                     GAGKSTLMNILAGNLSVDEGDLLLAGKSIKHLSVRKRAKDIARVFQDPKMGTASRLTI
                     EENMAIALRRGQKRGLGWGVKEKDRIQFQEALKELNIGLENRLKVDTQYLSGGQRQAL
                     TLVMAALVKLKLLLLDEHTAALDPKTSQMVMDLTQKIVEYHQWTTLMITHDMNHAIEY
                     GNRLIMLYQGKIVVDVKGEEKKHLTVEDLMHLFQKNSGQSLVSDELVLG"
     gene            complement(49445..49873)
                     /locus_tag="VQU30_000356"
     CDS             complement(49445..49873)
                     /locus_tag="VQU30_000356"
                     /inference="COORDINATES: protein motif:HMM:NF014684.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2446536.1"
                     /translation="MKTEIGLVLRSTGDNIPMSEANGVNVNTMKIVGYMISTGLIALC
                     GSLFAQNDGFSDVTSGTGTIVVGLSSEVLIHDLTIGGRLLSIGIGAIVYRLIILNIYE
                     IPNLDQNLVRLFNAILLALVLFAPALQKRLKIRGLKLRNE"
     gene            complement(49882..50322)
                     /locus_tag="VQU30_000357"
     CDS             complement(49882..50322)
                     /locus_tag="VQU30_000357"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001853886.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HET2446537.1"
                     /translation="MNFVLSSLSEGLLWSIMAIGVYLTFRILDIADMTAEGAFPMGAA
                     IVVSQIQAGANPWLATLLALLAGMVAGLISGMLHTKMKIPALLTGIVTLTGLYSINIK
                     IMGSVPNLSLGDSATVFKQLASLGLTNEGAVFSLSLVCLLLVWF"
     gene            complement(50367..51272)
                     /locus_tag="VQU30_000358"
                     /pseudo
     CDS             complement(50367..51272)
                     /locus_tag="VQU30_000358"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000512061.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
BASE COUNT        15175 a        11736 c         9477 g        15288 t
ORIGIN      
        1 attaaaaggt taagtaattt ttccaaaata cagcactcat atagacagta tcatcaatta
       61 tagccattgg gattttttga ttgccaattc catgtatctc tacacatgtc ttcaatcgat
      121 tttgttgtcc tccaatttaa ttccttatat gctttgtctg catttgcata ataagttgca
      181 acgtctcctg aacgtcttgg aactatttta taaggaatag ggatcttatt aacactttca
      241 aatgtattta caagttgtaa tacactagtg ccttctcccg agcctaggtt atagatataa
      301 acatctgttt tttcagatac tttttctaaa gcttttatat gtcctattgc taaatctact
      361 acttgaatct tttatctcat ttttcccttt ttcaaataag ttatctactc tatgatcagt
      421 tatttccatt tcgtttacta acatgacgca gtcacctagc atcatatact ccaacttttt
      481 ttctgaaagt ttagcaaata ttggtaagcg ataatatagt atattgaaac tagaatagta
      541 cacctctact tctaaaacat tgttagaaat cgatttgact gtcctgattg atttgtccta
      601 ttattatttc attttactat actctgttaa ttcatatgag tttaaaccga tttcatcttt
      661 aacctcgagt aaagcagttt caaatatttg tttaagagtt tttgattctt tacaattaac
      721 cgacaaactt tctgataaaa tatgtacaac ttctgagact gaataaccta tctcctcttt
      781 agaattatat aaatctgtag ctccaccaat aatccaaaaa tactgatttt gtgaacctac
      841 aatatcctca ttttctacgg aacttccttg tatcgaacaa attttattta tctttaccat
      901 aatacttcaa cccttttagt gtcaaaagta aaccaattcc tgtcactgtt aagaatagtt
      961 ccataatctt gttcgaacca gtctttggta atttttgttt tacatctact atttctttag
     1021 atttattaat atgattttca gtttctctgc catctccaac tattttatag tttacttctt
     1081 ctgtcttatt atcttgttta ttgtcgatct tgtcattcat ttgtctatta tctttacttg
     1141 agttaaactc tccgttcttc tggttactat caattacatt atttgaatta gattgttttt
     1201 cctctttgtt tttttctttt tcgtttttat cacttaaatt atttgttaca attttgtaaa
     1261 gcccattctc cgttacaata ttgaaattac catcgctatc acgtataaca gattctttcc
     1321 catttgcatt agatttgatg aatgatatat acttaccgga taaattataa aattggttat
     1381 ttaaaacggt tattttaccc tttgaatcct caataacaat tccttcttta ccaccgaata
     1441 tactattctc tgagactact aaattatcac taactcgtaa taattcaata tttggttgtt
     1501 ctgtttcctt agaattatta ttaattacat tttttgttac agtaatatct gatacttttc
     1561 ctaaatattc tgcactatct tttgcaactc gtatcgcttt tgttttagga tcggcaatat
     1621 taaatatatt ttcggcgata accacctgtt tatttaaatc taataggtct ttagtgtttt
     1681 tatagctata agcatttact aaagctgctc cgctttctcg ataatgtaca ctctctcctt
     1741 taactttctt atcaaagcga tttcctttga ttaatacatc agtgaatcct gtaaaacgta
     1801 cacctgcata catcatgtta tcaaaatgat tatttaaaat tttaatatta gaggggttct
     1861 gtgtcgacaa tgtttgatag tgtgtgccaa ttgctgttac taattcccca gatttatcac
     1921 ttttgccaaa ataggaattt tgaatagtca cattttcaga ttttttccca tcatcattca
     1981 aggcataagg aaaacctttt ctagttaatg gttcaatctg aatgctctcc ttacttatga
     2041 tttgcccatc cttcatcgtt ttgggtaagg cttgcccaag aaaacgagaa ttatcaacta
     2101 atacattttt cgaacctgca atttgaatag catgcccttg ataactatcc ttgaatgtta
     2161 cattttttat agttacgtta tttgaattcc caatagcaaa tgcacctgaa gaatttataa
     2221 gtggtagatt ttttgcttta gttccttctt cattcaaagc accgttcata tcaatcgtac
     2281 caccagaata actaatatct tctgttgggc cccattctac ttgcgcacca tcatccgtaa
     2341 ataaacctgt cataaaaaca atggaagggt gattcttaat atttatacca tttagaattg
     2401 tagctttctc attcaattct aagtgtgtat gactttttaa aaaaacaatt tcttttacta
     2461 aataagttcc ttcaggaaaa tatacatttc ctccacctag cccttgagct gcagcatcta
     2521 ttgcatcttg aattgcttgt cgatcatcat gaatcccatc acctaccgca ccataatctt
     2581 ttacacttaa agcagtatct tcaaattctt ttttgataat tctgtcactt ataacatctt
     2641 ccttataact cttattttca ttagtagata ttactgtaga ttcaactgtt ctgttgtcta
     2701 attgtgaatt ggaacgaata gtaccattag agctgatact attaacactt aacgaattat
     2761 ctaaaccatt agtggttgaa ttagaggcaa tcatttcagc agaacgattt tgattaacag
     2821 ttggtgaatt atctaaatca ttagtgattg cattagaaga ctcttttgta gccatcggtg
     2881 aagaactagt aacaacttca tccgataaaa taccttggct tcccaaaatt gaaattgcca
     2941 atagtaccga gcaagtcccc acctttaatt tacgaatact gaatacctca ttaggaacaa
     3001 aatatttcat cagaacctcc aattttttta ctatttttaa caattgatta ttacttttct
     3061 taaaatagat agaatgacac cgctgtcatt atctttatca tatattttcc aaattgaatt
     3121 gtcaaggaat aacacaagaa aatattaaaa tttatactct tcggaaatct cttcaaacta
     3181 ggtcagtgcc gccttgccct aagtctaggt tactgacttg gtcagttcta tagtagactg
     3241 aaactataat agtacacctc tacttctaaa acattgttag aaatcgattt gactgtcccg
     3301 atcgatttgt cctattctta tttcatttta ttatatctac aacctcaaag cagggttttg
     3361 agctatctat ggccaacttc ctagtttgct ctttagcctt ccattcaaaa gtgatgctat
     3421 ctttcttagc ttgaatataa aatatcccat ttactatatt taaatttgtt gatatgttgt
     3481 aaattataaa tgaaagaaca aatatcttgt catacaagca ttcgccaggg atatttacat
     3541 gaatatcgct catatggcgg attgaaacta aaacactaca atatatttct taaatagacc
     3601 ttctataaaa gctagattta acctcgataa aaatagatgc agtgcttcta aaatactgga
     3661 atagggcata taggtaatcg tagacaagtg ttttatagat tgtctcgcgg gagatctaat
     3721 gatgtatagc aagcatcact aaacatatag aatatttgtg ttattataat gtcaatatgc
     3781 tataaattct atcatgcaaa agaatgacta gaacatgaaa gacaggcaca aaactttgaa
     3841 caatattctg aaaacaaaaa aagacgcgag tttccacaat ctcactcatg gaaactcacg
     3901 tctttcaaaa aatagggtga attaaaaact agaacaagac actagatttt ctaaatgatg
     3961 tctagtaagg attctaaatg ctacaccaaa ttgctcacat cttatttcaa accacgggac
     4021 tcccacaaga aaggaaaatc ctataaaaat tctctctctg aggagagaga ggcctcaact
     4081 acaggtgtaa actattatca attgaaaaca acagttttta cactcaatta gactttttag
     4141 ggacaggatc actttcgctt gactgtagtt tgtcattttt ttgataaagt tagcactttt
     4201 tcagaaactg ttttgaaagt ctcaatgata tagtctactt cttcatcgct taatttagta
     4261 tgaagaggga gggtaatttc attctcaaag aaggcatagg ccttaggata gttcgtcata
     4321 tcaaatccaa gattcttata ggctgtcaag agaggaagcg gtttgtagtg aacattactt
     4381 gcaattcctg ctttagccaa ttcttggatg atgaggttgc gttcttctag gcttgctcct
     4441 tctacacggg tgatgtagag gtggcgtgaa gattcgacag tttcagtctt gtgtgccaaa
     4501 ggatggatgc gagaacctgc aaaaccacta tcatagcggt ccacaatgtc cttacggcgt
     4561 tgcaacaaac ttggatagcg gtccaattgt accaaaccaa gtgaagccat gatatcggtc
     4621 atgttgcact tataggctgg tgtaacgata tcgtattccc atgaccccag ttgcatcttg
     4681 gcaagagcat ccttagtttg cccgtgaagg gaaaggattt ggaattcctt gtacatctct
     4741 tcgtcatcaa tcactggatt ggctttccaa gtcgcacttc caccttctgc cgttgtaaag
     4801 ttcttaacgg catggaatga gaaggaagta aagtcagcga tagaaccaga aggttgtcct
     4861 ttataagtag atcccaaagc gtgggcacta tcagagacaa tgacaatacg gttaaaggcc
     4921 ttttgccact tgcttgaagc ggtaaagaag tcacgttttt tctccacgac ttggaacaaa
     4981 cggtcataat cgcaaacaat ccctgcgagc tctactggga taatcacctt agttttctca
     5041 gtgatagctt gctcaagcag gtcatagtcc atctcaaacg tatctgcttg gatatccacc
     5101 atgacagggg ttgctcccac gtgcgtaatg acactacatg aagccgtata ggttatggct
     5161 ggaacgatga cttcatcacc aggtcccact tcaaaaacgc gtaaaatcaa ctccagagcg
     5221 gctgtcgcag agttgagaca aacagtctta ggtgtctgtg tgtaaagaga caagcggcgc
     5281 tccagttctt ttgttttagg acctgttgtg atccaaccag aacgcagggt atccgctact
     5341 tcagcaattt ctgcttctgt gatatcaggc ggtgaaaatg gaatattgta atttggcatt
     5401 gatttgctcc ttttatctgt actcattctc ttatgactac tttattttag taccttaaac
     5461 acggtttgaa acatgatttt gatgtcccca aagaaactaa actctcggag ataggcgagg
     5521 ttatagcgca tcttttcagg aagaacatgc tccacatagg cctgatcaac tgacagacct
     5581 ttctctgtca tttgactgat gatggtgtcc tcatccttgt agttgatgct ggctggagag
     5641 gtaattcctg cttgcaagag caaggttgcc atcatttcag tgctatactg ctctgtataa
     5701 cgtggcactt caggtcgtgt accgacaaag gacatctcac ctttaaggac attgaccaac
     5761 tgaggcagtt cgtccaaacg gacacgtcgg atgaaatttc caaccttggt aatacggcta
     5821 tcgttagcag aagtcaccag atttcctttt ttatccgcat ccgtcaccat ggtacggaac
     5881 ttccaaatct tgaaccgacg gttgtactgg gtcacacgct cttgcttgta aatcactggc
     5941 cccttgctat ccaacttgat ccaaatgctc aagatgagaa agatgggaga ggtcagaacc
     6001 agtaagacca aggccaaaac ccagtccaag caacgcttga aaatcagcga acccttcctt
     6061 ttagagacaa gctggtagta agactcaacc tcgcttgatt tcatttccac aggcaagtct
     6121 tcccatttca gcatgctgtt ctcctttgtt tttattatac tatttgtcaa cactttttgt
     6181 caacactttt cattatacca caaaatggaa aaggcggtga aaaaaatctg taatttgaag
     6241 gatttccttc tagtactcaa tgaaaatcaa agtacagctt tgagattgca gataaagctg
     6301 acatggttta aagagatttt caaagagtat aggccatggc ccctgcctgc aaactataca
     6361 tcttgtgata ggttcctccc agagccaaga gttcctcatg ggttccactc tcgataatgc
     6421 gtcccttatc caagacatag atgcagttgg cgtcttgaat agtagaaagg cggtgagcta
     6481 tagcaatagt tgttcggccc tgtctcatct tcgccagaga agcttgaacc aagctttctg
     6541 tttcagagtc aatattggct gtcgcttcat ccaaaatcag gattttaggc tggctggcga
     6601 ctgttctagc aaaggcaaga agctggcgtt gcccagtaga gaagctcgaa ccacgctcgg
     6661 aaacagggga gtcgtacccc tgaggaagtt cttgaataaa ggaatctgca tccacaaagg
     6721 ctgccgcagc ctgaacctgc tcatcactga tttcttggta catggcgata ttggacttaa
     6781 tagttccatg atagaggaag ggttcctgca agaccaaacc gatgtttttt ctcagctctt
     6841 cttgactgaa atccctgata tccacatcat ccaagagaac tctccctgac tggaattcat
     6901 aaaagcgcat gaggacattg ataatagacg atttccctga acctgtatga cctacaaagg
     6961 caatggtttc acccttatta acagagaaag aaatgtcatc cagaatcgga tgtttaccgt
     7021 catatgagaa acacacatgt tcaaagcgga tattgccttc ttggactttg gcttgcccat
     7081 tttcttgaag aggttcatag gtcctctcgt ctaccagggc aaagacacga cctgcagaaa
     7141 ccatagacgt ttgcagtgtt gaaaagtttt gcgtcacctc aatcaaaggg tcaaagaggc
     7201 ggttgatgta ctggataaaa gcatacatgg tcccggccgt tatcccgata gaaagaccac
     7261 gatagccaaa ataggccatc aagacagcat aacctagaag tttcaacaaa ctcatggcag
     7321 gtctcaaaaa gagggcatcc aaggctacag aacggttggc atagaccaag tgctcttggt
     7381 tgatttcatc aaattctgcc tgcaggcgct tctcttgatt aaaggcctgg attattctga
     7441 ttccctcgat gttttcagcc agcttgctat tgatatctga caagagactt ctggttttct
     7501 caatgatttt cactgatttt ttccgataga gattgaccaa aaggaaaatc aaggggagaa
     7561 agagcaagac taatgctgtc aaacgaaaat ccaataccaa catggtataa agggttgtca
     7621 gaaagatgaa aactgctgag ataaagctag ataaaatccc agaaaacata tcactaatcg
     7681 tctcggtatc gttggtcaaa cgagaaacga tagaacctgc tggcgtcttg tcaaagtaag
     7741 acatgcccag tttctccata ttggcaaagg catcccgacg aatatcccta acaatactgt
     7801 aagacacgcg cgcaaagaga agattgccga catactgaac tacagtttgt aggatgtaga
     7861 gaccatagta gaccagcaaa acggtaacgg ctagttggtt aagattgctg agatactggt
     7921 cgataaagtg ggaagccacg aggggtatga cacttttaat gaccgtcgtc gctaggagaa
     7981 aactgagtgc caaaaaggtc aggagtctat aaggcttgag ataagacatc aagcgcttca
     8041 atacagccca ttgttcttgt ttattctgca tcttcttctc ctttcatttc taactgctga
     8101 gactggtagg tttgggcata ccagccatcc atcgctagca agtcttcgtg cctgcctcgt
     8161 tcgataattt gaccattttg tagaactaaa ataaaatctg catggacaac agcactgagg
     8221 cgatgggcag ttataatggt tgtcttgtcc tttcgcgtct ccttgagatt gtcgataatc
     8281 gcatactctg tcttggcatc tacggcggat aaggaatcat ccaaaatcaa gatatcaggg
     8341 tttaaaatca tagcccgact catagccaac cgttgctttt gaccaccaga aagactgact
     8401 cctttttcac caatcagcgt atcaaatcct tgaggcatgt ctacaatatc ttggtaaact
     8461 cgggctagct tagtagcttc ctcaacctct gaaaggggca agttaggatt gccaaagcgg
     8521 atattgtcta ggattgaagt cgcaaagaga aactggtcct gaggaacata gcccatgaga
     8581 ctgcgaagtt ctgtcaaacg atagtcccga atatcgtgac cgtttagata aatggcaccc
     8641 ttatccacat cgtattcacg caagaggagc ttgattaagg acgttttccc agagcctgtc
     8701 tgcccaacca agcccagtgt ttgccctttt gccaaactaa agtgaatatc cgtcagtgtt
     8761 tcctcatttt caaaagcaaa gctgtcaatg gcatactcca aacgcccatt ttcaatacca
     8821 tccagaggaa actcagggtc ttgtacagga gattcctgag acaaaagatt ttcaatccgc
     8881 tggtaagaaa ccttccctcg ctgagtagta ttaaagagga agccgatggc cataagaggc
     8941 cagaccagca tatccaaata gctgataaag gtgactagat taccaactgt aatctgccct
     9001 tcctgaacca tcaaggagcc aaccaaaagc gttaaaacat aggacgaacc aacaaacaag
     9061 agaaccatag ggtcaaagag actatcatat ttcatggttt gcaggttctt ttggaaggtt
     9121 aattcattga ctgcctgaaa agacttcaac tcgtctgcct gataaccgaa agacttggtc
     9181 actttgatac ctgatacgga ctcctgtacc ttgttattga gttcagaaaa agcagcttgg
     9241 gattcgccaa aggccttatg agtctttctc cctaggcgac tagtcgcata ggccatgaaa
     9301 ggtaggggga gaatggcaac aagagtcatc tgccatgaga tgctaaagag catggtcaac
     9361 aaagtcacca gagccgtgat agaggcatcc accgcagaca tgacaccgcc acctgctaaa
     9421 cgagtcaagg cattgatatc attggttgcg tgtgccatca gatcacccgt ccgataggtt
     9481 tgataaaagg ctggcgacat ttttgtgaaa tgcttaaaca agcgagaccg catgatctgt
     9541 cccaagcaat aagaggtccc aaggatatac atacgccaca catagcgcaa atagtacata
     9601 ccaaaggctg caagtagcaa gtaaaatagg ctaagaagga ggtcctgctg ggttaattgc
     9661 cccgatgtga tggcatcaat gactcgcccc ataaccatag gaggaatgag attgagaacg
     9721 gaaaccaaga ccagggccac aatcccgact agataacggt gtttttctaa cttgaaaaac
     9781 caccagagtt tttgaataat ggacataaaa tccctttctg attgcaaatg gaaacctgag
     9841 gccaatactc aatgaaaatc aaagagcaaa ctaggaaact agccgcaggc tgctcaaagc
     9901 actgctttga ggttgtagat agaactgacg aagtcagtaa cctacatacg gcaaggcgac
     9961 gttgacgcgg tttgaagaga ttttcgaaga gtacaagacc ccaggttttt cttattcata
    10021 agttacgact gtaacagcac ccttgtcata ttcagcaata aagatattgg ctacattgtc
    10081 atgcccttgt ttgctgaggt tatcaagcaa ccactcttcg ctacgaccaa tcgattccaa
    10141 gacgtctact tgaatcacac cgtcagtcac aactggatac ttaggatttt catctcccat
    10201 ttgcacaacg atgagttgcc cattttgctc ttgcacagct cgtttgactt gcttcatctg
    10261 gaaaatccct tggctacgaa gtttgagggc tacatccgat gcagacaaac caactgaacg
    10321 acaggcttat gggtcaatat tcccattttt gataaggaga gttggcttac catcaatcaa
    10381 acgtttcaca aagtgaacat tgttgttgag ctatttgaga gtcaagatca gtttgattaa
    10441 aatttcgata taattaagtg tcatttgttc acatccacca gttcaattgc gtctgtctta
    10501 tacaattcga ctttctctaa caggtacttg tctggctcac ttccgtttag ggcacgataa
    10561 tagcgatctc ccaccttgat aagtgcgcca tctgtgtttg tggaagtatt aacatggact
    10621 tctgacttgt ctactcccaa atctttggaa acaacctcga tgaaatgaag tgaagtttga
    10681 aatttattgt tagaaacttg attgttttga taagtcgtga tgctgaccaa aagcatagct
    10741 aaataaggcc agagctgaaa tcatgaccaa ctcacgaaat ttggttcctt ttttatcatg
    10801 gtatgccttg aaagcaaaaa aaactgtcac agctaataga acaatcccaa agccaaccat
    10861 gataccattt tgctgaccga tttggctgag tacatagtca taagagtaga atttcatgta
    10921 ttttcactcc ctttcataaa atcattctta attataaacg aaagagagta atttttcaaa
    10981 ccatacgttg gggaaataga tctttttttg gtataataaa atctataatc tgaatgaaaa
    11041 aggtaacttt atgaaactta tctcatggaa tattgattcc ctaaacgctg ccctaactag
    11101 tgactcagct cgtgccaaat tgtcccaaga agtcctacaa accttggtcg ctgaaaatgc
    11161 tgatatcatt gctatccaag aaaccaagct ttctgccaaa ggacctacaa agaaacacgt
    11221 ggaaatttta gaagaactct tcccaggcta cgaaaacacg tggcgctctt cccaagagcc
    11281 tgcccgtaaa ggctatgctg gaaccatgtt cctttataag aaagaactta cacccactat
    11341 cagcttccca gaaatcggtg ccccttctac catggacttg gaaggccgta tcatcactct
    11401 agaatttgat gcatttttcg taacccaagt ttacactcca aacgctggtg acggtctcaa
    11461 acgcttggaa gaacgccaag tctgggatgt caaatatgcg gagtatttgg ctgaactaga
    11521 caaagaaaaa ccagtccttg cgaccggtga ctacaacgta gcccacaatg aaatcgacct
    11581 tgcaaatcct gctagcaacc gccgttcacc tggatttact gacgaggaac gtgctggatt
    11641 taccaaccta ttggcaactg gatttactga taccttccgc catgttcatg gcgatgttcc
    11701 tgaacgctac acttggtggg cacaacgcag caaaacttct aaaatcaaca atacaggctg
    11761 gagaatcgac tactggctca caagtaaccg tatcgctgac aaggtcacta aatctgatat
    11821 gattgactca ggtgctcgcc aagaccatac accgattgtc ttggaaattg acttgtaagg
    11881 attttctata tggactacaa tgcggtcatt cccgagtttc ttgtatcgaa tatcgaacag
    11941 tcccggtcct tctactgtgg tttactgggt tttaggattg aataccaacg ttcagaagaa
    12001 aactttctct ttctcttgaa gagtgtcaac taatgttaga ggagggaaca aaggatcaac
    12061 tagctgaact gacctacccc tttggtcgtg gagtcaatct ctcctttggc ataaaggatg
    12121 ttccaaaact ctatcaaaaa gtgatggagg caaactatcc tatttatcgt cccttgacca
    12181 aaagaaagtt tcgtgtcagt gatccctata tctatcctca taaatttgca gttttggatc
    12241 cagatggcta ttttttaaga tttagcgagt agaataataa aaattgggaa aagtctttaa
    12301 aagttagaaa aaggcatatt gtcaggtgtc taaaaacttg atagtatgcc ttttatgatg
    12361 gaaaaatctt ctaatactct tcgaaaatct cttcaagcca cgtcaacgtc gccttaccgt
    12421 aggtatataa tactgactct gtcaattcta tccacaacct caaaacagtg ttttgaggtt
    12481 gtggatagct tcctagtttg ctctttgatt ttcatttagt ataaatgtta gcttacaatg
    12541 gagtttttgt tcaccctctc ttctgtttgt tcgtttttta aaccaaaaca ctaacaaaat
    12601 agttgatttc taaagttatt tagtgtaaaa taaaaacatt ggctcaagcc tatttaaaat
    12661 tgaatatcgt tttacttgtt tatgtcgtga attggcacga cgtttctaca aggtgccgga
    12721 acacctaaca ataagtaagt cagcagtgag atatggccgt ttttgccatg cctatttggg
    12781 ggacttactt agagattaag taggtctttt ttgaatattt ttaatatttc ccttaattag
    12841 tgcggacggg aggtgaaatt atcctgtgaa taatttcagg aatccaggga atttcatccc
    12901 taatttttga gcccctagct ctttcatttc taggcttagg ctaaaatagt tccccgaact
    12961 attttactct caaaaatccc gtcatagaca ataacaagat tattgtctat gataccacta
    13021 caacgggaaa tatttgataa gactcgcttc gctcgtaata gttttatcaa atatatagca
    13081 ttagcaaaag ggatcactat agaaacattt aaacaacaag taaattaact tttagacttt
    13141 aggaggtctt atgaaattat tagaagagcg catcctcaag gatgggcata tcttgggtga
    13201 taacatcctc aaggtagatt cctttttaac ccaccaagtt gactttagct tgatgcgaga
    13261 gattggtaag gtttttgcgg aaaaatttgc tgctgccggc attaccaagg tcgtaaccat
    13321 tgaagcgtcg ggtattgccc cagccgtttt tacagctgaa gccttaaacg ttcccatgat
    13381 tttcgccaaa aaagctaaga acatcaccat gaacgaaggc atcttaactg ctcaagtcta
    13441 ctcctttacc aagcaggtga ccagcaccgt ttctatcgct ggaaaattcc tctcaccaga
    13501 ggacaaggtt ttgattatcg acgatttcct tgctaatggc caagctgcta aaggcttgat
    13561 tcaaatcatc gaacaggccg gtgccacagt ccaagctatc ggtatcgtga ttgagaaatc
    13621 cttccaagat ggccgtgatt tgcttgaaaa agcaggctac cctgtcctat cacttgctcg
    13681 tttggatcgt tttgaaaatg gtcaggtcgt atttaaggag gcagatctct aatgcaaact
    13741 caagaaaaac actcgcaagc agccgttctt ggcttgcagc acttactagc catgtactca
    13801 ggatctatcc tggttcccat catgattgcg acagcccttg gctattcagc tgagcagttg
    13861 acctacctga tttctacaga tatcttcatg tgtggggtgg caaccttcct ccaactccaa
    13921 ctcaacaaat actttgggat tggactccca gtcgttcttg gagttgcatt ccagtcggtc
    13981 gctcccttga ttatgattgg gcaaagccat ggtagtggcg ctatgtttgg tgcccttatc
    14041 gcatctggga tttacgtggt tcttgtttca ggcatcttct caaaagtggc caatctcttc
    14101 ccctctatcg taacaggatc tgttattacc acgattggtt taaccttgat ccctgtcgct
    14161 attggaaata tgggaaataa cgttccagag ccaactggtc aaagtctctt gctttcagct
    14221 attactgttc tgattatcct cttgatcaac atctttacca aaggatttat caagtctatc
    14281 tctattttga ttggtctggt tgttggaact gccattgctg ctactatggg cttggtggac
    14341 ttctctcctg ttgcggtagc tccacttgtc catgtcccaa ctccactcta ctttgggatg
    14401 ccaacctttg aaatctcatc tattgtcatg atgtgtatca tcgcaacggt gtctatggtt
    14461 gagtcaactg gtgtttatct agccttgtct gatatcacaa aagatccaat cgacagcacg
    14521 cgccttcgca acggttaccg cgcagaaggt ttggccgtac ttctcggagg aatctttaac
    14581 accttccctt acaccggatt ttcacaaaac gttggtttgg ttaaattgtc aggcatcaaa
    14641 aaacgcctgc caatctacta cgcagctggt ttcctggttc tccttggact gcttcctaag
    14701 tttggtgccc ttgcccaaat cattccaagc tccgtcctcg gcggtgccat gctggtgatg
    14761 tttggttttg tatctattca agggatgcaa atcctagccc gagttgactt tgctaacaat
    14821 gaacacaact tccttatcgc agctgtttca atcgctgcag gtgtcggtct caacaacagt
    14881 aatctctttg tcagcatgcc gacagccttc caaatgttct tctcaaacgg aatcgtcgta
    14941 gccagcctac tcgccattgt cctcaatgcc gtattaaatc ataaaaagaa ataagaaaaa
    15001 gaggtgcgag cctctttttt gtttatcaca aattgattat aaatacaatc aatcccaatt
    15061 cccatctaat tgaattggac ctatttcaaa ttctttaaaa tattatgttc caaatcgtta
    15121 atattatata agaatggtaa aatatcaaat gtttctcgta aattattctt agccttatac
    15181 caaccttgtc catcagtaat ccacataaac tcaacattag gaatagcttt aatttcttca
    15241 gcaatcattt tgtaagatct agccgtctca tttaattttg aaccacttcc tgaataaaaa
    15301 ttaacctcaa tcagataaag cacttgttca ttttttatga caaaatcaaa acgtttcaca
    15361 gtattcccat cattcgtaat agcagataaa tcgacagaaa aaatttcctc tatttcattt
    15421 tgttcaatct ctttaaataa attctctcct aaaatatacc cttcagcttc aagataactt
    15481 tgaacaatat tttccatcgc atctccagtc cgatttttgc gcccattagt atccatacca
    15541 acctcaacac ctgtaacgta gtcaactaaa tttgatacta aatgattttg caataaatca
    15601 aatatacctg atttttccaa aaacatagta tattcttcaa tactatagtt tcgtttacta
    15661 aaatcaaaat agaaatcttt tatcggatcc ttaacaataa tcgtatctct caaacgttta
    15721 gcaataagta gaggcacaac tttcaaaatt tctggataat tttgatataa gtctaaaaaa
    15781 tcctcttgta tatttttact accaataaga ctattcataa tatttagagc aacttttata
    15841 ctagatacat ttttataaac cttgggaaaa tctgtataat aagtccagtc agctactgtg
    15901 tcggtcatcg ttgacaacca ctcatcaaaa tttctagttt gtttcatttt ctgcctccaa
    15961 cctcttcctt gcaattttta aatattcttt ttcagcatcg atacctataa atcttctacc
    16021 taaccgcttc gcaacaacac ccgtagtgcc actaccaaca aatgggtcta gaatatagtc
    16081 accctcttta gtagaggcta aaataatgcg ttctaacaaa tactctggtt tttgagttgg
    16141 atgtttccca gcccattttt caactttctt tgttaaagaa cccgtccaga catctttcat
    16201 ttgttttcca tcattcaatt ctttcattaa atcataattg tagtaatgac gagctttttt
    16261 atcatttttt ctggcccata aaatggtttc agtagaatgg gtaaaataac gacaagataa
    16321 attgggggca gggtttgttt tctgccaagt aatattattc agaattttaa aaccttcttg
    16381 ttctaatgcc attccaactg agtatatgtt gtgcaaacta cctgaaatcc ataccgtccc
    16441 attaggcttc agaacttctt ttgctaggcg aatccattta cgattaaact catgtttttc
    16501 ttcgaatgaa gaaattttat cccaatctcc tttatcaaca gaaacaactt gtcccccaga
    16561 attagatatt ccaccattac ttaaaaaata aggtggatca gcaaaaatca tatccatact
    16621 ttctggtttc atttttgata agaacttgaa cgtatctgaa tgaacaagaa tcatcttatt
    16681 tttattgtag tatggttttg tcataagaac acctccatac ttatattcgt tatttttcat
    16741 aatttgtgac tataatttca gaaatttttc ctcgacttga agattttgct ccattagttc
    16801 gggtagcttc aacataatgt atattaaaat ccttatacaa ctcctctact aaagcactag
    16861 aagaatttga taacataaca taagctcctg tatcactcaa tctcttaaag gcatctctta
    16921 atcttacttg atctgcaaaa gagaatccct catgagtata agacgtaaat gcactcgtct
    16981 cagacaatgg aatatatgga gggtcaaaat acacaaaatc tcctgttcga acatctacaa
    17041 ttgccttttc aaaatctccc actttaattt ctagttgatt gttatttaga taaactgaaa
    17101 tagcagatat caattcctca tcaacaattt taggattctt ataacgtcca tatggaacat
    17161 taaattggtt cttagaattc acacgatata gaccattaaa gttcactctc aacatatata
    17221 gaatacgtgc agctctttgt acttcggaca tcatatctat tctttcatca cgatctgcag
    17281 aacgtaaatc taaataatat tcttttgaat tatattcctg atgaactttc aaaatttcaa
    17341 tcaattcttg aggattgtcc ttaatttgtt gatagcaatt tattagttca gcgttaaaat
    17401 cattaataac tgcatcttta ggagccaaat caaaaaataa agctccacct ccaacaaaag
    17461 gttcgaaata cctgttatag gttttaggca ttaattctct aataacaggc aataattgtc
    17521 ttttaccacc tgtccatttc gtgaacggtt gtaaagtaac tttctttatt tcttttatct
    17581 tcatgctttt aattatacca tagaaattaa aacacaactc ttgtattttc taccacatta
    17641 ctaaattttc tattttagaa ttaaatcata tcaatataaa aaaatgagta aggcaaatct
    17701 tataaattcc aaaattcacc tcactctatt aaattactct ttatatcctt acccgtcttt
    17761 cctcagacct ttggcctgtg acaaacatag taaaggttgc tttgcagaca tttctgccct
    17821 cttgattggt gatatccaca tccatcacac aggttgtacg accttgatgg acacattctc
    17881 ctttaatggt caatacatcg tcgagttttc ctgccttaag gtagttgata gaggattgga
    17941 gtgtcacccc atcaagtccc agcgagataa ccaccaaacc actgatttgg tcacatagtg
    18001 tgaatagata gccaccatgg gcattgccat agtagttgag cgacgagttc actactttgg
    18061 tcgtcaccac aacgtgacca tctctcattt tttcaatttc gtaattttca aaggcagata
    18121 tagcgtcaaa atgaaagtct ttcatcgttt cctcctgata tttcaaatga cactatgata
    18181 ctacttttta taggactgtg caaggagaaa gctcctagtc tagtaaaatt ccgacatgtt
    18241 ccacaaagcg cataaaggct gtctgccctt gttctgtctg cttgtagact cctgcatcct
    18301 caagtacacg cgcaaagata gcacccacag agtccttgac gattgcaagg gctttttctt
    18361 tatccgttag gtctggatgt tgggatttga gttggtctgc ccactcctga tgataatcgg
    18421 caactgtaac agcttctcct acaagatagc tagcgacttg ctctacttct tctttcagac
    18481 gtggtggcaa gattgccaag cccatgacct caatcaagcc gatattttcc ttcttgatat
    18541 gttggacatc cttgtgggga tgatagatgc catcaggatg atctgctgaa gtctgattgt
    18601 ctcgcaagac caagtccaac tcaaactgtc catcacgctt acgcgctatt ggtgtgatgg
    18661 tgtgatgcgg tgtcccgtct gtctctgcta aaatctgcac actagaatct gaatactgac
    18721 gccattcctg gaaaatctta tcagctaagt taatcaaatc ctctttggaa tccgaagtca
    18781 agcgtaggac agacattggc cacttgataa ttccagcctt gacctgctca aaaccagcaa
    18841 atcggaaggt cttttgcaag ggagccaatt ccataggaaa tacgtgacgg cctccctgat
    18901 aatgatcatg agttagaata gagcccccca caatcggcag gtcggcatta gatccagcaa
    18961 aatatcctgg aaactgctct acgatagcca acagacgttc aaaactctga cgactaatgg
    19021 ccatgggacg atgctggcca tctaaaaaga tacaatgctc attaaagtaa gcatagggcg
    19081 aatactggaa accccattcc tgaccaacca tttcaaaacg gataatccgg tggttgctgc
    19141 gagctgggtg gttgacccga ccatggtaac cctcattctc taaacaaagt tgacactgag
    19201 gataattact agcttgcacc aacttggcta ccgcaatctc tttcggatcc ttttcaggct
    19261 tagagagatt gatggtaatt tcaagttctc cataatcaga tggaacacga taaacgatat
    19321 ttttagcaat ggccttgagt ttgatgtagt catttttctg actgagttga taaaaatcct
    19381 ctatcgcttg ctcaggagag taggcatagg cttcccagaa gtcacgattg acctgactcg
    19441 gacaaggagt caccaagtcc atcaattcag taccaaggat ttcacgcgca gtctgactat
    19501 cctcaatcgt ctctaatcga acggcttcct caactagctg gtccttgagg tcaatcaatt
    19561 tatccagatt ggtctcaact tccaaaacac cttctcccac tcgtgccaaa acacgattgg
    19621 tcaggtagat tcgatccatt tcctcaaatg aactttcaga aatgacatgt gttacaaatt
    19681 tatctactaa ggtcactata gagcctcctt ttgactagtc aaggacgcga gtgccacctg
    19741 caacttcagc gatatagaag cttggagcgt atccaactac ttcctcgtag tgtttgccta
    19801 cagcttcctt aaaggcctca acagtatctt tttgaaccaa ggcaatggca cagccaccaa
    19861 aaccagcccc tgtcatacga gcaccgagaa ctccttcttg tgcccaagct gtgtgaacaa
    19921 gagtatccaa ttccaaacca gttacttcat aatcatgctc cagagaaacg tgtgacgcat
    19981 tcatcaaacg accaaatgtt tccaaatcac ctgcttgaag ggctgcttga gctttaaggg
    20041 tacgttggtt ttcaaacaca gcatggcgag cacgtttcaa acgattttca tctttaatca
    20101 gatagctata ttggtcaacg gcccactcgt ccaattcacc cagggtctga atatccaagg
    20161 caacttgcaa ttcttccact gctttttcac actcagcacg acgttcattg tatttagagt
    20221 ccgccaattc acggcgtttg ttggtgttca tgataacaac gacattgtcc ttcaaatcaa
    20281 gtggcaccaa gtcgtattct aaagtattgg tatctaagta aatagcacgt tggtcagccc
    20341 ccataccaat agcaaattgg tccatgatac cagagttgac tccgataaag ttattttctg
    20401 tttgttttcc gattttaacc aaatcgagac gctctagttt taaatcaaag agatgctctg
    20461 ccacgactcc tgtcaagagc tccaaggatg ctgaagaaga caaaccagca ccatttggga
    20521 tattcccata aacataaaaa tcaaaacctt tgtcaatcac gtgcccagct tcttgcaaga
    20581 aatgaaggac accttttgga taattggtcc agttgtgctc tttttcaaac ttgaggtcag
    20641 cgagaggcac ttcgataatg cccttgtcct caaagttagc tgagtagaaa cgcaagactt
    20701 ggtcgtcacg cttacgagct gcaccgtaag ttcccaagga aatagcagca ggaaaaacgt
    20761 gcccaccgtt gtagtctgtg tgttcaccaa tcaaattaat gcggcctggt gaaaagaagg
    20821 tttggtctgc ttcttgacca aaaacagcaa gaaagtcttt gcgaagggct tcagtagtaa
    20881 gatgttgtgc catatgaatt ctcctttgac tgtccgttaa gccaccttaa cgtataatcg
    20941 ttttctttct attgtatcca aggaattttc caagatcaat cctttttact aaaattttag
    21001 taaaatatca gtaaaaagaa gaaaaacatg atatactaac ctaatcaagg aggatttatg
    21061 gctaccttaa aagacattgc acagctagcc tctgtctcta tcgcgaccgt atcccgcgtc
    21121 ctcaatcgcg accagagcct atctgttaca gaagaaacca gacaccgtat tttaaccgtt
    21181 gctgaagagc tgggctacac caagcacctc aagacaggcg agtcccacaa acccaagcaa
    21241 aagattgcca ttatccaatg ggtcagcgaa caaggggagc tggacgacct ctactactac
    21301 cagattcgcc taggaataga aaaaagagcc caagagttgg actatgatat cttgcgctat
    21361 tttaatgacc atccttttac cttaagcgag gaagtgattg ggattctctg cattggaaaa
    21421 tttagccgag ctcagatttc tgcctttgaa gaataccaaa aacccctggt ctttctagac
    21481 agtgatacac tttctctggg gcatacttgt attattacgg atttttacac tgccatgaaa
    21541 caggttgtcg attatttcct cagccaagga atggaccgta tcgggattct aacaggcctt
    21601 gaagaaacaa ctgaccaaga agaaatcatt caggataagc ggctggaaaa tttcagaaac
    21661 tacagtcaag caaaaggaat ctatcatgat gaactggtct ttcaaggaaa ctttactgcc
    21721 cagtctggct atgacttgat gaaggaagcc attcagaact tgggagacca actcccacca
    21781 gcatttttcg cagccagcga tagtttagct atcggtgccc ttcgtgccct ccaagaagct
    21841 ggaatcagcc taccagaccg tgtcagcctc atttccttta acgacaccag cctgaccaag
    21901 caggtttatc ctcccctctc cagcatcaca gtttatactg aagaaatggg gcgagcaggt
    21961 atggatattc ttaacaagga agtcctccac gatcgcaaaa ttcctagcct gaccatgctg
    22021 ggaaccagac tgacattaag agaaagtacc ctaaatcaag aataggataa cataaaaaac
    22081 gaatagagtt ctaaaactcc tattcgtttt ttattcgatt acaatcatag acttaatggt
    22141 cttacgttca tccatatctt tgtaggcttg gtcgatatct tccagtttat aacttgaagt
    22201 aaagacgcga cctggattga tatcaccatc aaggacggct tttagtaaaa attgcttatc
    22261 gtatgttgta gcagaagctg ccccacctgc tacagagata ttttgcataa atgtcgaacc
    22321 aagagcacga ttattatagt gtgggactcc tacaaagccc atacgccctc cattatgaag
    22381 aacacctagc gcctgttcta tagcagcctc cgtaccaaca cattcaagtg ctgcgtctgc
    22441 tcctccaccg aggatttcac gcaccttggt aattccttct tgaccacgtt ctgcaacaac
    22501 agctgtcgca cctgactcca tagccatctt ttgacggtct tcatgacggc tcataaggat
    22561 aatttgtgat gctccacgca tcttagccgc gatgacagca cattgaccaa cagccccatc
    22621 accgataaca acaaccttgt cccctttttg aacatttgca acacgcgccg catgatagcc
    22681 tgtcggcatg acatctgcaa gagtcaaaag ggactggagc atcccttctg tatagtcaga
    22741 aggttgacca gggattttaa ccagcgccca gtttgcatag tggaagcgaa tatattctgc
    22801 ctgaaaatca ccccccaaat tattgccaat atgattgtcg caagaaccgt caaatccagc
    22861 aagacaggca tcacactcac cacatccatg tgtaaaaggg acaatcacaa aatcacctgg
    22921 tttcaccgtc gtaatggctt ccacagcttc ttcaacaatc ccaatcgctt cgtgtccact
    22981 atttttgtgt ccagctttcg tttctggatt acggtacctc cataaatctg aaccacaaac
    23041 gcacgcacga accacacgaa taatcacatc atccgcttct attatttgcg gacgttcaat
    23101 gctagcaagt ccaacctgac ctgcctttgt atatactgct gatttcattt aaaattttcc
    23161 ttccttataa agtttaattt tgagatttaa acgatttaaa gctgtctgta gctgagacaa
    23221 gcgctcctct aatttttgct tttcctcttc taaaatacca agcctctcct ctctcgtttc
    23281 atctcccttt tggtagagcg acatatagtc aactaaacta tctacagaga cacccgccga
    23341 acgaaaacac ttaataaatt ccagcgcttc gatatcctga tcttgaaaat cacgaatccc
    23401 agtagcagta cgagtaatcg gtggcacaag accaacccgt tcataatacc gaatcgtatc
    23461 cgctgaaatt cccaacaaat cactggcaga tttaatattc acacgctaac ctcctctcat
    23521 ttcattcact gaattcacgc tattctaact cacttatctt attatataac tttgagttga
    23581 ctccaagtca agcattttgt atctaatcga aaaattttta tcattaacaa tcatatatct
    23641 ggagtttata caatgctctt ctcttaccaa tttttgaaat atttaaataa taaagaaatt
    23701 actctattcc aaataagata gtacccaagt atttttcact tttttctaat gttgatgctc
    23761 ataactccgt tccaagtcac acacctttcg cttatgggtt tggtgagttt ctaggtcagc
    23821 atcaatttca atggtaatat tttgaaaacc acaatctttt aggaaaattc gaatagactc
    23881 tttacaagtt tccatatgtt ccatttcttt tagacaaaca tggacaatgg catttttttc
    23941 caaagcatcc atagtccaga gattaagctg attaaggctg gccacattgt ccaatcgctc
    24001 caggccactc tttacttgct tgatatcaag accttctggc acagcatcca agaaaatctt
    24061 gagtgtagac caaaaacgtg gaagggcttt tgaaagaata aagaaagaaa tgacaaggga
    24121 caaaagagga tctaggatat accagtccgt aaatcgaaga acaatcgcca tcaggataac
    24181 agctacccac cctagcgtat cttccagaaa atgcagactc agaatagact cattctttgt
    24241 ctttccctta ccaaccacca gactcgctaa cagattgata gtaatcgcaa taattcctaa
    24301 ccagagaatc ccctcatcat tgactggttg cggatgcaaa atcttcgtga cattttccaa
    24361 aatgactaga acagagcccg ttacgagaat cacagctgtt accaaggctc ctagcaggct
    24421 aaaccgctta tagcccaagg tgtactgatt gtcttcttca cgattggaga ttgtttctag
    24481 aaaagctgat attccaattg caatcgcatc tcccaagtca tgcacagagt cagcaagaac
    24541 agcgctagaa ccaaatactc cacctgcaat aaactcaaca atggcataag tcaaatttaa
    24601 gaaaaaagcc acccaaacag catattttgc cttcatattt ctcattcctt tgttataata
    24661 gatttatgaa caccttgttc attatcatta tccactaaaa ctcaaagaaa ggatagaagc
    24721 aaaacgtcag ctttattcag ttctgaacaa tttgccttaa gtgtccatat gactaacatt
    24781 gaccgccgta tcagcaaaac caaaaaagcc atctatcaag cttttataca acttttgaat
    24841 gctaagggct acgaggccac tactgttcag gatatcattg atctcgcaga tgtgggacga
    24901 tccacctttt actgtcacta tgagagtaag gagcttcttc tggaccagct ctgccgctac
    24961 ctcttccatc atctttttga aagagagcaa gccatttcaa ccgaggacta cctcgcccac
    25021 ctctttctcc attttcataa aaaccaagac catatcacca gtctgctatt ttccaaaaat
    25081 gactacttcc tccgtcaact ccataaagag ctagaacacc atgtctattc cgtgctagct
    25141 gataatttaa aagaagccca ccctaatctg cctacttctt acctccaaca cttggtcatg
    25201 tccaacttta tcgagacatt gacctggtgg ctcaaaaaag gtcaagattt cacagaccag
    25261 gaagttgtcc aattttatct agaccttctc attcctaaaa attgaatata gagtaaagct
    25321 tcagttgtct tatttctagg ttactgagtt ttttatcttt tcaacaacaa aagaggaccc
    25381 gccgatcctc tttttcatac tataaatcct tgattatcaa ctatatctgt tttaatcgaa
    25441 atctcaaaac agcactttca aacatctttt cctagttaag taaatcagta ttctgcttag
    25501 ctgccttgct ccattgatac caaccaacta gactgttaat gagataaatt agatatttcc
    25561 cttgaatttg caggctttct ccccaccaga gatagattga aaagacattg gtagccgccc
    25621 agaatatcca ctgttcacgg taaacagctg tcatgaggat ttgccctacc ccattggttg
    25681 catctgtgat tgaatcacga tagggacgat tggcaccaat agactgataa atgaagccaa
    25741 aggccaacca ccaaagcaca ctaatggaaa gatactttgt ccagcccttg ccgtccagtt
    25801 tacgcgcgac aaactcctgc ttttccttct taaactgtgc ctgataaatc caaactagaa
    25861 gtccaattgg ctgcatgact gtgaagtaaa gtgtcgtcag cacctcacca taaaagcctt
    25921 tctgtagggc caaaataagg taaataacag agttaatcaa gccaaaaaga taattacttg
    25981 ctcgaccttc cgatacaaag attacacaga taatccctgt caagctacaa atcatcccaa
    26041 tccagtcaac aatacgatgt tcgtaaacca actccagcca gagaggaaaa cttcctaaaa
    26101 ccagcaaata aatccactgg gcaaaactac gatgggcaaa gaggtcatcc cagatagcct
    26161 tcatagttcc tgaaaatcct aaatcagcca tagccgcaac catacgacgg taaccacctg
    26221 acatttcacc tagggttgtt ttgatatttt caattttctt ttgcaaataa gtatgcatca
    26281 tttctccttt tgtttttaaa gagccgtgtc tggatagact ttcggacgca acgctctatt
    26341 agataatgaa ctgcctatac acaagatttc taaccttagt cgacatgagc tgaaacctct
    26401 tatttgttaa gtagttcaca aaatattata cacctatttt atgaatagtc aactgtcttt
    26461 acagtaaaat tttagaaaat catgaaaatt ttctctttct ttccatttta agtgacattc
    26521 agtcattctc acatcaaaaa agcccagacg aaattgtctg agcattcttt tatctagtcg
    26581 tttaaggaag ttgagttcag tatgtttaaa gtctctgtcc catcatttct tcaacaaacc
    26641 ttgttcttgg agaaactcct tggctacttg ctttgctgac ttgccttcaa caccgacttg
    26701 gtagttgagc tggctcatct ggctttctgt aatcttacca gccaatgtat taagaactct
    26761 ttccaactct gggtgtttct tgagaagagc ttctttcatg agtggagccc cttgataagg
    26821 tgggaagagt tgcttgtcat cttccaagac ctgtaaatca taacgctcca attccgcatc
    26881 agtcgaatag gcatccgtga tttgaatatc ccctgactga atagcctgat agcgaagggc
    26941 tggctccatg gtcgctacat tgagattgag accatacatt gattgcaagc ccttatttcc
    27001 atcttcacgg tcgttaaact cgagtgtaaa acctgccttc aactgccctt ccactttttt
    27061 caagtctgaa atggtcttca agccatattc ttgagcaatc tttttcggaa cagctacagc
    27121 ataggtgttt tgataagaca tgggtttgag ataggctaga tgatcctgct tagcaatgcc
    27181 atcacgcgcc acctgataaa cctgttctgg ttcatgactc accttgggtg atggttgaag
    27241 caaactttca gtcaccgtac cagtaaattc aggatagatg tcaatatcgc cttttttcag
    27301 agcttcataa aggaagcttg tcttcccaaa attcggttta acagtcgcag tcatgctggt
    27361 attttcttca atcagcaact tatacatatt ggccaaaatt tctggttctg gacctatttt
    27421 cccagcaata accaagtttt ccttctcttt ttgaaccaaa agagctggac tataagacag
    27481 acccagtaat aaagccacca aggcaaaacc tgagaaaatc gtccgtaatt ttgctttttc
    27541 catcactttt agtaggaagt taaaggcaat ggctagcact gcagaagaaa gtgccccaat
    27601 caaaatcaaa ctggcattat tacggtcaat tcccaaaaga ataaaggaac ctagtccccc
    27661 tgcaccaatc aaggccgcca aggttgccgt accgataatc aaaacagctg ccgtccgaat
    27721 cccagacatg ataacaggca tggcgagtgg aatttcaaat ttcttgagac gttcccatct
    27781 ggtcatccca aaggcaatcc cagcctcttg caggttcgga tcaattccct tcagcccagt
    27841 gatagtattt tgcaaaatag ggaaaatcgc ataaatcact agagctgtca aagccggcaa
    27901 ggtcccaatt cccatcaaag ggataaagag ccccaacaag gccagagacg ggatggtctg
    27961 gaaaatacct gcaatctgca agacccagtc ggccagcttc tcatgatagc gaagaaaaac
    28021 agccaaggga atcgcaagca aaatagctag taacaaggtc aaaagcgaca actgcaaatg
    28081 ttgagataga gctgtcaacc aatcactaaa acgatcctga aaagttgcaa ttaaattagt
    28141 catgaacact acctccaaac aagtctgcta caaagtctgt tgcaggcgct tttaaaattg
    28201 tctcgggatt cgctacctgg cgaatttctc catcctgcaa gacagcaata cggtccgcca
    28261 acttcaaggc ttcatccgta tcatgggtta caaaaatcgt tgtcatccca aactctttat
    28321 gcaattcttt tgtcagaacc tgcaactgtt ttctcgaaat agcatccaag gccgaaaagg
    28381 gttcatccat gaggaaaatc ttgggctgac caatcatagc tcggacaata ccgacccgtt
    28441 gctgttctcc accagataat tcactaggta agcgatgccc atactcggct actggtaaac
    28501 caaccttagc caaaagctct tctgttttct tcgtaatttc ttccttgctc caccccttca
    28561 tttcaggaat gagagcaata ttttccgcaa ctgttagatt tggaaaaaga gcaatagcct
    28621 gtaaaacata accagtagaa agacgaagtt cacgctcatc atagtctttg atgcgcttcc
    28681 catccatata aatatttcca tcagttggtt ccaaaagacg gttaatcatc ttgagcatgg
    28741 tcgtcttacc tgacccagaa ggccctacta aaaccataaa ttccccatcc tcaatctgta
    28801 agttgacatc tctcaagaca tccttttctg tgtagcgcag tgctacattt ttgtattcaa
    28861 tcattctttg tcctcaattt aaaacttccc tcgattggtc aagtcttcta ccttaggcat
    28921 aacttcctta ttatcccaat gctccacaat tttcccgttc tctaaacgga agatatcgta
    28981 ctgggcataa gcaacgccat caatctgagt ctgaccatag ctaaccacat agtttccttg
    29041 tcctaagagt tggaaaacaa agtcaaaagt gacactatat tcagccacat agtttttata
    29101 agcagcactt ccttgtccaa tatcatgatt atgctgaatc aaatcgtctg ccacataatc
    29161 actccactgc tctagctccc cattttggaa aatttctgtc aagaaacggc gaaccagctt
    29221 tttattttct gctttcttgt ccaaatcctt gatttcaaaa tctccaaaaa tttgatctag
    29281 ttggtcattt tcaggtgttc gatagtagtc aacgacatcc caatgctcaa caatacgacc
    29341 attctcatcc gcacggaaag tatccgtcgt cacccattga gcttctccac cattcagata
    29401 ttgatgaaca tgaacaaaga ccagattgcc atcctcaatg gtgcggacaa tcttaatctg
    29461 acgctctgga tgacgctcaa agaaatctgc aaagaaggct gcaaatcctt ctttcccgtc
    29521 aggaacacct gtcgaatgtt ggatataggt atcccctaca gactgggctt gagcctcagc
    29581 aactcgcccg tcttgaatgg catggatgta taggttgtga gcatttttca cttgttgtga
    29641 catattctaa acctcatttc ccttctcttt cagattcgcc aaaattcttt cttgaaaacc
    29701 ttcaaattgg tgaatttctt cctctgaaaa tcctttgtaa aagatagtat ccaatttctg
    29761 actgacacga tgccccactt ctttctggaa cttgcctaac tccgttaaaa ctaaatactt
    29821 cttacgcttg tcttttccac acggactaac aattacaagc ttttgttcct ctagcttttt
    29881 tatcatagtc gtcagcgtat tattcgcaag cccagtcgca agcgcgatat ctgtcgcagt
    29941 tgcgcagcca gtttcactat tccataaaac cgctaaaatc ttgccctgtt cacccctata
    30001 aagagcctca ggatcttgac tcagtaactt ttgaaaaatc cgcccattca acaaacgaat
    30061 atgatgggct agcaaatgac tatctttcat aacacctcca atttatttcg atatcgaaat
    30121 gaataaaata attgtaacac tcatcgttct aactgtcaac tatttcgatt tggaaataat
    30181 ttttgataat tatccacacc accatactcc ggctcaacta acttttaacg agagtttcta
    30241 aactccttcg tcctccagtc tacaaaagcc ttccattcgt actatcctat attttatgag
    30301 gggacacatt tttcctatca gaccatttat tttaaagata gaagtaaatc ataattgctt
    30361 ccatctgttc ttttatagta tattgaagtt agactagagc actgtatctt ctaaaacatt
    30421 gatagaaagc gatttgaatt tcccaatcaa tttgttcgta tttatagcat tttgaaacta
    30481 gaataggaca ccatgactgc taaaagattt ctataaattc atttgatttt cctaatcaat
    30541 ttgttcatat cttatttcat tccgctataa tttcacctta ccctatcttt ttcgtagcac
    30601 ccttcaaaca gcctatcccc taccgtttga cgattcctca cttcgctcca cttccattac
    30661 agaagtttct tcactactat gggctcggct gacttctcat gattccttgt tactactatt
    30721 tgaacgctca cgagatagat cttacaaaaa atgctttgat ccacaatgga atcaaagcat
    30781 tttaaagagt tcctcataca taagcgcaga agtcgcagtt cctctgtact tggcttcttc
    30841 tcttttgata aagcgagcca agttgagcaa ctcaggtgct ggatgtttgg gatttaggag
    30901 caattcacga ttgaccaggc ctgagagacg aactgcctgc aattgctcat ttgtagtagg
    30961 cagtttttta gcagtctcta ggagagcagc aactaaatct tcactcaaat catgtcgagc
    31021 atgattgtaa agatctttta taaggctttc taggtttggt tctgccatcc ctaccacctc
    31081 ccttatggtt taataatgtt taatcaaatc aaccgttgaa cgatccaatt tcttcaccaa
    31141 ggcttgtaag aaagcttgcg cttctaggaa gtcatccatt gcatagaggg tttggtgaga
    31201 atggatataa cgagcgcaga caccgatagt tgttgatggg acaccaccat ttttcagatg
    31261 agctgcacct gcatctgttc cgcctttacc acagtagtat tggtacttga taccagcttc
    31321 ttcagccgtt gtcaaaagaa aatccttcat ccctgggaga agcaagtgac ctggatcata
    31381 gaaacgaatc aaggttccat ctccaatctt gccttgacca ccgtagacat cacctgctgg
    31441 tgagcaatca actgcgagga agacttctgg gtcaaacttg gttgtagagg tatgagcgcc
    31501 acgcagacca acttcttctt ggacgttaga acccagatag agttcattgc cgagtttttg
    31561 acctgataaa gcttcagcta gctcgcttac catgaggaca ccgtagcggt tatcccaagc
    31621 ttttgagatg atattttttt cattggctgt caaaattgca gaactatctg gtacgatggt
    31681 atcaccagga cggatgccaa aactttctgc ctcagccttg tccgcaaaac caccatcaaa
    31741 aacgatatcg gcaatggctg gcatggttgg tccccccttt ccacgagtca aatgcggagg
    31801 aacagaacct gaaatcacag gaatttcatg accatcacga gtcaagagtt tgaaacgttg
    31861 gctgctaacc accatggggt tccagccacc gatttctacg acacggaagg taccatctgg
    31921 cttgatttcg ctgaccataa aaccaacttc gtccatatga gaagcgacca agacgcgcgg
    31981 tgcatccaca gcttctgaat gtttgatacc aaaaatacca cccaagccat ctgtcaccac
    32041 ttcatccaca tgcggtgtca acttttcacg aagataagca cggacaggcg cttcatgacc
    32101 tgagactgca gcaagttctg ttacttcttt aatttttgaa aataatgttg tcatttcagt
    32161 tccttctttc tttcatccat tttaccactt tttataggag aaggatagtg ggaaggtgga
    32221 tttctaagtt agtatcttag tcctgctcta tcttagaaaa ggatagtatt ctcttgcatg
    32281 tagtgcaaaa tctagtaaac attccaaaat taactcgaat atttatttcc aaacaaaaaa
    32341 acaatacacc atcaaagttg tttgtatttt tcatgaaatt tacagaaaat agttgacttc
    32401 cctttcttct ttctttaaat atatagttgg ttgagtttgg aatagtacgc tgtagctgct
    32461 gaaacatttc tagaaattaa tttgactttc ctaatagagt tgttcatatc ttatttcaat
    32521 ttactatagt acaaaactag aaaaggaaaa aatcatgacc aaaacaattc ttgttacagg
    32581 tgggactagc tacattggct cccataccgt taaagctctt ttaaatgctg gctataaggt
    32641 gcatgtcctc gataatctct ccacaggaaa tcgagcggct gtggatagtc gtgctagctt
    32701 taaagaactg gatgtttatg atgctagcgc cttaaaggct tacttagaag aaaatcagat
    32761 tgatgctgtc ctccattgtg caggtgaaat tgttgtgagc gaaagtattg aaaatccaag
    32821 taaatacttc actgccaacg ttgctggtat gaaccaagtt ctcaaagtct tatctgaagt
    32881 tggcattcaa aaaatcatgt tctcttcgac tgcttctctc tatggaaata actgtattga
    32941 caagccagtg actgaagata ccctgctcga ccctgtcaac ccttatgcag agacaaaact
    33001 gatgggcgaa cgaatgattt actggatggc caatcgctac gactggaaat atgttatttt
    33061 ccgttacttt aatgttgctg gggctgaaat ggatgcttca aacggtctgc gtgtgaaaaa
    33121 tccaactcac atcattccaa atatcaacaa gaccgcattg ggacaaaatg atagcttaaa
    33181 aatatttgga gatgactacg atacacgtga cggttcatgt attcgagatt acatttatgt
    33241 cttggacctt gcataggctc atgttaaagg aatgaactac ctatttcaag aagacagttc
    33301 ttctcaaatc tttaacttag gaactaaaaa aggctatact atcaaagaaa tctttaaaac
    33361 tgctgaagaa ttactaaatt aaaaaatccc acacgagatt gttgctcgac gtgctagtga
    33421 cccagccagt gtcctagcag atgcttcaaa agctaaacaa tatcttgatt ggacggctag
    33481 ctactccctc gaagatatta ttttatcaga ttaaggtaaa aacattttag aataggataa
    33541 caaaggagaa agtcttgttg ctctctcctt gttgtattta ttaaattgtc agaaatttta
    33601 ttgacagatt agaaaaataa tgttacattt atatccgcag atatctttcg ataccaaatc
    33661 tacatgaaag gacggggtat gaaactttct cattatttaa ttggcttact tctactccta
    33721 gtctttctct ctattagcat tgggaccagt gatttttcat ggggaaagct atttgatttc
    33781 gaccagcaga catggctcct ctttcaagag tcccgtctcc caagaactat cagtattctc
    33841 ctgactgcct ctagtatgag tatggcaggc cttctcatgc agactattac ccaaaatcag
    33901 tttgctgcac cgagtacagt tggaacgact gaagccgcca aactgggaat ggtgctgagc
    33961 ctttttgtct ttccatcggc tagtctgacc caaaagatgc tcttcgcttt tgtttcatcc
    34021 atcgtattca ccctcttctt cctagccttt atgaccattt ttactgtaaa ggaaaggtgg
    34081 atgttgcctc tgattgggat catctatagc gggattatcg gctcagtcac agaagttatc
    34141 gcctatcgtt tcaatctggt tcagagtatg actgcctgga cccagggctc cttctccatg
    34201 attcagaccc atcagtatga gtggctcttc ttaggcctca tcatcctgat aaccgtttgg
    34261 aaattatccc aaaccttcac catcatgaat ctggggaaag aaatcagcga gagtttgggg
    34321 atttcctact ccctacttga aaaactggcc ctctttctgg tggcgctaac gacaagcgtc
    34381 accatgatta ccgtgggtgg cctaccattt ctcggagtta tcgttcccaa tcttgttcgc
    34441 aagcgctatg gagataatct aagtcaaacc aaactcatgg tcgcactggt tggtgccaat
    34501 ctagttctgg cttgcgatat cctatcccga gttctgatta ggccctatga gttgtctgtc
    34561 agtctcttgc taggaatcat cggtagtctc ggctttatcc tacttctctg gagaggggga
    34621 cgaaaagatg cagactaaaa gcaaacatac caagctcttc tggattctca ttattcttgc
    34681 catcggagct tgtcttctct acttttggcc catcactcac ttgtcagcct ttgcttggaa
    34741 gttgcgttcc caaaagatca tcgtttatct cttggtagcc atcgcgactg ggatttcgac
    34801 cattagtttt caaaccctga cggaaaatcg cttcctgacg cctagtattt tgggaattga
    34861 atccttctac gtcctactac aaaccctact actggttttt gaaagcaagt ttcttcaact
    34921 tggcaaatcc cctatcttag aattcctagt cttacttctt gtccagtccc tcttctttct
    34981 caccttacaa ggttacttga agacactgat gaagcaagac ctggtcttca tcctgctgat
    35041 ctgtctagcg ctcagaagtc tctttcgaaa tatcagcacc ttccttcaag tcctaatgga
    35101 tccaaacgaa tacgataaac tgcaaaatag tctttttgcc tcctttcaac atctcaacac
    35161 ttccatccta gccatcggtt ctctgatcat cctcgctttg acaatctttt tctttcgaaa
    35221 agcagtcgtt ctagatgtct tgcacctgca aagagaaacg gctcagatat tgggactcga
    35281 tgttgaaaaa gaacagaaag agctcctctg gggaatcgtg cttttgacct caacggccac
    35341 tgccttggta ggacctatgg ccttcttcgg ctttatgctg gccaacctca cctacctgat
    35401 tgtcaaagac tatcagcaca agttactctt tatagtggcc attctggttg gatttattag
    35461 cttaaccttg gggcaagcct tgattgaacg agtctttgca ctggaaattc gtatcagtat
    35521 gatcattgag agtgtgggtg gcttcttatt ctttatctta ctatatagga ggtctcgtca
    35581 gtgaaactgg aaaacattga caaatccatt caaaaacagg atattttgca aggcatttcg
    35641 cttgaagtca gtcctcaaaa actgacagcc tttattggtc caaatggtgc tggaaaatcg
    35701 actctcctct ccatcatgag cagactaacc aagaaagatc agggagttct cagtatcaaa
    35761 ggacgtgaaa tcgagagctg gaattcgcaa gaactggccc aagaactaac catcctaaaa
    35821 cagaaaatca attaccaagc caaattgact gttgaagaac tggtcagttt tggacgtttt
    35881 ccctacagcc gaggtcgact tagatcagaa gactgggaaa aaatccgaga aactctgaac
    35941 tatttggaac tgaccaactt aaaagaccgc tacatcaata gcctgtcagg ggggcaactc
    36001 cagcgcgtct ttatcgctat ggtactggcc caggatacgg actttatctt gctggacgaa
    36061 ccactcaaca atctcgatat caagcaaagc gtcagcatga tgcagattct tcgacgactg
    36121 gtggaggaac tcggcaagac cattatcatc gtcctccacg atatcaacat ggccagtcag
    36181 tatgcagatg aaattgtcgc cttcaaggac ggccaggtct ttagcaaggg aagcaccgat
    36241 caaatcatgc aggctgacct gctcagtcaa ctttatgaga ttcccatcac gctagctgat
    36301 atcaatgaca aaaagatctg tatctatagc tagtaacata aaagctcaag ttagagaacc
    36361 ttcagtctct tagtcaataa gattaagaga ctccctaaat cgttatcaca ttttaaaaag
    36421 gagaaattat gaaaacatcc cttaaacttt atttcactgc cctagtggcc agcttcttgc
    36481 tcctacttgg tgcatgtagt acaaactcaa gcactagtca gacagagacc agtagctctg
    36541 ctccaacaga ggtaaccatt aaaagttcac tggacgaggt caaactttcc aaagttcctg
    36601 aaaagattgt gacctttgac ctcggcgctg cggatactat tcgcgcttta ggatttgaaa
    36661 aaaatatcgt cggaatgcct acaaaaactg ttccgactta tctaaaagac ctagtgggaa
    36721 ctgtcaaaaa tgttggttct atgaaagaac ctgatttaga agctatcgcc gcccttgagc
    36781 ctgatttgat tatcgcttca ccacgtacac aaaaattcgt agacaaattc aaagaaatcg
    36841 ccccaaccgt tctcttccaa gcaagcaagg acgactactg gacttctacc aaggctaata
    36901 tcgaatcctt agcaagtgcc ttcggcgaaa ctggtacaca gaaagccaag gaagaattgg
    36961 ccaagctaga caagagcatc caagaagtcg ctactaaaaa tgaaagctct gacaaaaaag
    37021 cccttgcgat cctccttaat gaaggaaaaa tggcagcctt tggtgccaaa tctcgtttct
    37081 ctttcttgta ccaaaccttg aaattcaaac caactgatac aaaatttgaa gactcacgcc
    37141 acggacaaga agtcagcttt gaaagtgtca aagaaatcaa ccctgccatc ctctttgtca
    37201 tcaaccgtac ccttgccatc ggtggggaca actctagcaa cgacggtgtc ctagaaaatg
    37261 cccttatcgc tgaaacacct gctgctaaaa atggtaagat tatccaacta acaccagacc
    37321 tctggtatct aagcggaggc ggacttgaat caacaaaact catgattgaa gacatacaaa
    37381 aagctttgaa ataagccact tcaaactcaa tttaatactc aatgaaaatc aaagagcaaa
    37441 ctaggaaact agccgcaggt tgctcaaaac actgttttga ggttgcagat gaaagctgac
    37501 gcggtttgaa gggattttcg aagagtataa aattttgaca ttctaaaacg catcctatca
    37561 agttcactca aacctgatag gatgcgtttt tatcattttg aaatctattt accccacctc
    37621 attccccttc ttgatttcgt ttaagggaaa agtggtctgg aacggggtcc ttacctgttt
    37681 tcgaccaggg atgacaacgt aaaatccgag ccaagcccat caataccccc ttaaaaccat
    37741 gtttttcaat agcctgaatc atgtagttgg aacaagtcag ctcaaagcga caagagggtg
    37801 gaaagactgg tgagataaaa cgttggtaaa agcgcacagg cgctattaaa attcgtttca
    37861 ttatttctta gttacagcca tggtgtgtag ttggctgatt tcttttttat taagacgacg
    37921 ggattctcct ggacggagtc ctgtcaagtc taggtgtccg aaacgagtcc gagacaactt
    37981 atctacttgg agaccaacag cttcaaacat ctttttaacc tgatggttac gcccttcatg
    38041 gatggtcaac tgcaccacag agcgattttt gactgggtcc actttgagaa tttcataaac
    38101 agctggcttg gttttcttac catcaatctc aagaccacgg gtcaaggggc ggagattgtc
    38161 cttattggcc acacccttaa cacgcgcgac ataaaccttg tcaatctcat tacgagggtg
    38221 aatcatctcg tctgtaaagt ccccatcatt ggtcaaaatc aagacacctg atgtatccca
    38281 gtccaaacga cccacagggt aaatacgctc tttgacattg ggcaagaggt cgacaaccgt
    38341 cttgcgaccc ttatcatctg tcacactgga aatcacaccg cgtggtttgt taagcagata
    38401 gtagaccttt tcttcgttgt agataggttg accttcaact tcgaccttgt cgcctgactt
    38461 gatagtggtt gctagttcac gcaccacttg gccgttaacc gtcaccaagc cttgcttaat
    38521 cagctcttct gcttttctcc tactggccac acctgcgtgg gcaatatact tattgattct
    38581 catcttcttc tatcctttca ccaaataatt ggctttcttg ggcttgaatc tcaagctcat
    38641 caatcactgg taattcttct aaatggttta tccccatgta atctaggaaa taatccgtag
    38701 tcacatagag gttggggcgc cccaatactt cctttttccc gtcttccttt atcaggtcaa
    38761 aagcctgcaa ctttgccaag gctccactcg agttaactcc acggatggca tcaatttcta
    38821 tccgcgtaat cggctgtttg taggcaataa tggacaaggt ctcaagggca gcccgagaca
    38881 agctctggtt gataggcgcc ttagagtatt ccttcaaaat ctctgcaaat tgagacttgg
    38941 tcaccaatct ataagcacca cttgtctcaa tcaaagccaa actggaatct gggtcctttt
    39001 catacttctg ggctaatttt cctaaactct gctggatgcc tgtcggtggc agagagagga
    39061 gttcagctaa ctggcggacc cgaatcccat cttcacccgc tacaaacaag agcgcttcta
    39121 tttttgctaa agtactcatc tttcctctct atcaagtcta gctttgaggc acttgacttt
    39181 cttccttctt ttccatgaga tagatatctc caaaactctc ctcttgcacg aggatcagct
    39241 cctgggtttt gattaactct agggttgcca aaaagagggt gatgacctct tggacattct
    39301 gggcttcctt gaacaaatcc tgcaagcgca attgatctcg tccaatcaag gactctttca
    39361 cgataatcat catgtcctca atcttatact catcccgcaa gatagtcgtg tgattttgtg
    39421 caaactcctc ttttttcttg gctaggatat ttgaaaaagc caaaaagagg tcaatggtcg
    39481 tcttgtcatg cacaagctcc gcatcttcgt aaatcaactc tgtcggcgct ttggaataat
    39541 actgggcccg ttcttggtgc ttggcttcca agtgctcacc caagagcttg aacttgcgat
    39601 attcttcgat ttgagagagg aggtcctgct ccaggtcatc ccccaagtct gtcacttctg
    39661 ctaccttcgg aaggagttta cgactcttaa tcagcatgag ctgactagcc atgaccatgt
    39721 actcacccgt cacttccaga cgcatggcct gcagggttga aacataggct agatactgtt
    39781 cgatgacttc cgtaatgggc acatcgtaga tatccatctg gtacttagaa accagatgca
    39841 agagcaagtc cagggggcct tcaaaatctt ttaatttaat atccattatc tatatttttc
    39901 taaggtcagg actgttttta atcctaattt ttttgcaatt tcgtacaaat cgaccttgtt
    39961 ttctatttgt cttagaataa actgttcacg taagacttga gctgataagg atggaaaacc
    40021 tttctccttg acaaaagatt ctaactgacg aaaggcccac tgacgagaat agggtttctc
    40081 tcctctttca aaaagatagg tctgccccat caagggttcc aattctgaaa gcaaggccgt
    40141 gggaatggtg acaatcctct gttgggaagc cttgctgatt cgcaacacct gaaaatccag
    40201 attgatgtcc gcaaccttga tggctaaaat ctcactgggc aagagcccca tttctaggat
    40261 taagagcgct agcaagcggc cctctggatg gtcgctttcc tgccaaaaag agtctaggta
    40321 tagaatctct ggcttttccg tcttcttttc agcttgtttg gctaattcca agcggtaaaa
    40381 gctgtccacc tctccttttt gatagagaaa gtatagaaat tggttacagg ccgaaatctt
    40441 tcgcttctgg gcgctgattt ttagattggc tagctgggct tggtaaatct tgagactggt
    40501 ctcagaaatc cgctcaccta ccatgtctaa aaattgctcc aaatcatact tataggactg
    40561 cttggaattg acagacaagc cctgcttttc ctctaaaaag gctgaaatcc tgtctctcat
    40621 tggcatcgaa tctcatattc cttactaaag tcatgcaaga gggcattaac ggccttgagg
    40681 atggacttac gcgtaataat cccttggaaa ataccctctg catccacaac cggtaagaag
    40741 gactcatcta ctagcttgtg caagacctcc gtaatggtga aatcaggcga aacaaccgct
    40801 acgtccgttt ttgtcatatg aacgatatcc gtatccgcca tgatttcttg gctcaagtca
    40861 tgctccatct gataagccat aatatctctg agtccaatcg tcccaacaaa ctgtttttca
    40921 tctgtcacaa cgggaacacg ggtataggtc atctgactga gcaagagggt cgcatgatcc
    40981 gcattgtggg tatcaatcaa cacagctaga tttttagcag gggtcaaaaa agtttcctcc
    41041 tgccccaaca agaaagtctc aaactccttg gcaatcatcg gctaaactcc ttggacaaac
    41101 ctggatacac ctcgtgatct cgtgtcaaaa agtccacttt gaagtaacta tcatcaatct
    41161 ccacacgagc atagagacat tctctgatgg tacctcgtgg ttgactgata gaacctggat
    41221 ttagaaagag gatcttgcct tccaaccaag cacttggcac atgcaagtga ccatagaggc
    41281 agatagcggc ctcttcctcc tgagcccagt agtccaactt ttgaaagttg aaattgatgt
    41341 caaacaagtg accatgagtt tggataatct tggtcgaacc aagctcagtc accagacgtt
    41401 ctgggtagcc ggcgtagaag tccatgtttc ctttaacaac gcggatgccc tcccaaagtg
    41461 gagaatccgg acgtagttca gaatcgccgt tatgaaaaac ggcatcgact ttgcccacat
    41521 agcgatcacg gacttcttcc acaatcaagc tatcgccatg ggaatcgctc attacaatga
    41581 tggtttgctt tgccatgatg gaaatacctc caaaagtttc ttaacggcta aggcacggtg
    41641 agattgacta tttttttctt ccagggttaa ttcagctgat gacttacctg tctctcctac
    41701 aaggaagagg ggatcatagc caaagccatt ttcaccctta ggttcaaagt taatataacc
    41761 tgaccagtct gcttcaacaa ctaaactttc cttatttggg ctggctacga ctagggttgt
    41821 gtggaactga gccgagcggt ccttgagttc aaagaccatg gccaattcgt gcaagagttt
    41881 ggcattattt tcacggtcag ttgctcccac acctgcgaaa cgagctgacc agacgcctgg
    41941 taagccacca aggacatcga ctttgagacc agaatcatct gccaaaacca tcttgcccgt
    42001 taattgagaa atggtttctg ccttaaggcg ggcattttct tcaaaggtca tacctgtttc
    42061 tgctacttca ggcaggtcag ggtagtcatt aagattttcc acatcgtagc ctaacttatc
    42121 aaagatagct cggaattcct tggttttgcc ttcgttacga gtcgcaatca acaaggtttc
    42181 tctgaccttg cttgtctcaa agaaatcatg aacattgacc ccttctttag gcaattctac
    42241 atacaagagt tgcccatttt caaccaagag cagggcccca tgacgttgaa taacttccaa
    42301 gtttcgtccc atttcttgat taagcatgtc taccacaaag gagaacaaac ggtaggtaga
    42361 accatagcgt aaaacagtaa ctgaaagcgg gaaaccatac tcttcatctc caaatatttt
    42421 ggagaattca aacagaggaa aatctgtctt atagtcgctc aaactgttaa cgccaccaaa
    42481 aatactataa gacccaacat accaatcctg gtcatcctta tattcataaa ttttatttgt
    42541 cataattcta catgctccac ataaatctct ttttccagcc attcttcacc aatttgtgca
    42601 aaactttggc tactggctgt tgtgtaaaaa cggtgatgga gtggtccagc atcgcgacca
    42661 cgattgattt caaaataatt gagtaagact gagatatccc gtacgcactc tgccccacta
    42721 tcgatgagct gaacctttgg ccccatgaca ttttggataa tagggcgaag gagtggataa
    42781 tgagtacagc ccaaaatcag gctatccacc tttccaacca agggacgcag ggtttcatag
    42841 accaccttct tggtaacact ggttgacagg gcacctgact caaccaaggg agcaaacttg
    42901 ggacaggcca agctctccac ctgtaagtcg ggatccagat catggatttt ctgacggtat
    42961 atgtctgatt gtaccgtcat gggcgttcca atcactccga ttttcccacc ttgactggac
    43021 ttgatggctg ccgaagctcc tggcaaaatt acacccaaga caggaatatc tagttgagcc
    43081 ttgatttctt cccagacgac cgcagtcgca gtgttacaag caatgacaat cattttgaca
    43141 tccttggtca agagaaagtt gaccagctgc caagtatatt cacgaatttg ctcagctgga
    43201 cgggggccat agggcgcccg cgccgaatct ccaatataga cgatttcttc atggggaagc
    43261 tggcgcatga gctcgcgcac aacggtcaag cccccgacac ccgaatccaa aaaaccaatt
    43321 ggtcgattat ccatacagtc ttctttctag tcttttttct gattgatcgt tcattatgat
    43381 tccttgtact gaacgaactg accgacagct tgatagaatg tcaactacct ctctcttaat
    43441 cataatcaaa tatcaataga atgcaaggaa aaagtctcat ccctaaacca taaccaacat
    43501 agtgagaagt ctggaacttt catcccagac ttttccttat ttattttttc tttttattgt
    43561 tagcaagggc tgccttttgt tggcggatga tttggtggta aacttgttgt accttagctt
    43621 cgcttggttt ttgaccattt gcactcaaaa gagtacgaac tgcttcagca ttcaaacgtg
    43681 ggttgtcagc aaattctttt tcgatttgct tacgaaccaa gtacattcct ccaagagctc
    43741 ctcctagaaa agctagcaca atcaatacaa ttgctaaaag taaatccatc atttttctcc
    43801 tgtttctttt tgagtccctt tcattatacc acaaactagc caccctgacc agtttgttct
    43861 acactttcag ggatggaata gacagcaaaa agaaccctgc ttttctgaaa aagaggtctc
    43921 cttgctaagt ttaatttaca taaatagcca gtgtttgata gggttttagt agaattttct
    43981 cagacacttc tgcatcttca tagtttgaaa tcaaaatctg tccattttgg tagactgctg
    44041 gcaagtcgat ttccacttct ttagcataaa agttattgag cactagtaac ttttgatcct
    44101 caaactggcg ttcaaaagcg tagacttgtt tgctatcttc aaaggctggt ttgtaacttc
    44161 cttctgaaat gattggcatt tccttacgca gtcgaatcaa gtcttgatag aaggtaaaaa
    44221 tcggaccctg gatttcattt tctacattga tgtctttata ggatttacca gctttcaacc
    44281 aaggagtgcc tgttgaaaat cctgcatttt ccgaagcatc ccactgcatg ggaatgcgtg
    44341 aattatcacg cgacttagct tgaataatct ggaaggcttc ttgctgactc tttccttctt
    44401 ctaggagcat ctgataggca ttaagcgatt cgacatccac gtaatcagcc atagaatcat
    44461 agtctgggtc aatcatcccg atttcctcac ccatgtagat ataaggtgtc ccacgtgaca
    44521 ggtgaatgct ggctgctagc atggtggctc cttccttgcg gaagttttga atatcgacaa
    44581 aacggttcaa ggcacgtggt tgatcgtgat tgttccaaaa gagggcactc caaccgtctt
    44641 tatcactcat ttccttaccc caactatggt aaagactctt caactcttca aaatcaaagg
    44701 gagccaaggt ccacttttgt ccatccttat agtccacctt gaggtgatga aaattaaagg
    44761 tcatggataa ttcctgacga tcaggcgacg aatagaggac acagttttcc atggtggtag
    44821 aagacatttc cccaactgtc ataaagctat cgtcagatcc aaaagtggct tggttcatca
    44881 tacgcaaata gttatgaacg atgggtttgt ctgtataagc tggcttccct tcattttcag
    44941 gacagtccac tgaaacctcg tccttaccaa tcaaattgat cacatcaaat cgaaaacctt
    45001 tgacaccctt gtcgcgccag aaattaacaa ccttgaaaag ctccttacgg acattgggat
    45061 tgcgccagtt aaggtcagcc tgggtctcat caaataggtg aagatagtat ttcccagtat
    45121 ccccgaaagg cgcccatgca gaaccaccaa acttagactg ccaatctgtt ggttggtctt
    45181 ggatgaagaa aaagtcttga taatacttat caccagctag ggctttctga aaccattcat
    45241 gctctgtcga acaatgatta agtaccatgt ccagcataaa gtcaatcttg tgctctttac
    45301 cgatacacac catttcctca aaatcagcca tatcaccaaa aagaggatcc actgccatat
    45361 aatctgaaat atcgtaacca ttatcccgtt gaggacttgg atagaatgga ttgagccaga
    45421 ccatatccac acctagtttg gctagatagg gaatttttcc gataatccca cggaaatccc
    45481 caataccatt gccagtggtg tctttgtaag attttggata gatttgatag actacttttc
    45541 ctttatcaag tgtcatctgt ttctcctttt ctgataaaag ggaggaagca gtcttccgtc
    45601 cctatttgtg ctatttcaat tatactcaat gaaaatcaaa gagcaaacta ggaagctagc
    45661 cacaggttgc tcaaaacact gttttgaggt tgcagataga gctgacgtgg tttgaagaga
    45721 ttttcgaaga gtattagatt cgtgtagcga ccatgagaga tgctccagct tgaatcgttg
    45781 tcggataagt tccgggaata gtcgctgtat aagcatcttg gttggtgatg ataacaggag
    45841 tttctgtcac cagacctgca gccttaatga catccatatc aaaacgaatc agttgctgac
    45901 caactgtaac gtgatctcct tggactacaa gactttcaaa acctttgcca tcaagaccta
    45961 ctgtatccat accgatgtgg atgagcaatt caactccctc gtcagagaca atgccgatgg
    46021 catgcttggt agggaaaaga accgtcactg tcccattaac tggagaggtc aactcacctt
    46081 ggcttggttc aatgactaga ccttgcccca tgacacctga tgcaaaaata ggatccgtcg
    46141 cttgactcaa ttctttcact tggccagtta gtgggctgat aatttctacc gaagtaagtt
    46201 ctactggttc atggttcaca aattctgctt cttcttgagc aacgaattct gcctgcaagt
    46261 tcgtatcgcc ctctgttttt gtaaagagac cagccttgcg gaagaagaaa gtcaagagca
    46321 ttggaacaac aatcgcaact agcatagttc ctgcaaatgg cagcatgtat tgaggttgaa
    46381 tagagagaat acctggcaaa ccaccgatac caatagaagc cgcagttaca ttaaaagtaa
    46441 cggataacat gcctgcaagg gctgaaccag tcatcccagc aacaaatgga taaatatatt
    46501 ttacgttaac cccaaaaaga gctggttctg taacaccgag ataggctgaa atggttgcag
    46561 gaagtgaaac ctgagcctca cgctcatcat ggcgatgcat gaaataatag gcaaacacgg
    46621 ctgagccttg agcaatatta gaaagagcaa tcattggcca tagggcagtg ccaccagcat
    46681 ccgcaatcaa ttgtgtatca atggcattgg tcatatggtg cagacctgtg atgacaaatg
    46741 gagcgtagag ggcaccaaaa attgcaccga agagccattt aactggacca gttaaacctg
    46801 ccaagacaac tgatgaaagt ccttgtccaa ttgtccaacc gattggtccc aaaacagtat
    46861 gagccaaaat caaggctgga atcaatgaca agaaaggtac aaaaatcata gaaatgactt
    46921 ctgggatatg cttgcgccag aagatttcaa gataagatag actcaaacct gcaagcaagg
    46981 ctgggataac ttgggcttgg taaccgatac gattaacagt aaaatagcca aaattccaaa
    47041 cccagtttgc cgcgatatca gctgctggcg ttgaagcaac cgcataggca ttgagcaact
    47101 gaggcgatac caaacagatt ccgagaacaa ttcccaaaat ttggctggtt cccatcttac
    47161 gagaaacaga ccaagtaatc cctactggta agaactggaa gatagcttca ccaggcaacc
    47221 agaggaaatg attaacacct gcccaaaact gagaggattc tgtgatggtc ttgccatcca
    47281 acatcgacca atggacacct tccaagacat tacggaaacc gaggatcaat cctccgacta
    47341 tcaaggctgg aataatcgga gtaaaaatct ccgccagagt ggtcatgaca cgttggacca
    47401 cgttttgatt actcttagct gcagacttgg ctgcttcttt ggaaacaccc tcaatacctg
    47461 aaacagctgt aaaatcatta taaaagatgg gcacgtcatt tccaatgatt acctgaaatt
    47521 gacctgcatt tgtaaaggtt cctttaacag ctggaattga ctcgatagct ttaacattag
    47581 ccttcttatc atttcctaaa acaaagcgca tccgtgttgc acagtgagtt acggcagtca
    47641 cattttcttt gcctccgatt gcctgaagca gatctttggc ttcttgttca aattttccca
    47701 tttgattctc cttatacttg tcaaagcaag tttgatttga taagtatatt gtaaacgata
    47761 ccaaacttgt ctgcaacttg tttggtataa aaagggtgtt tttttgtaaa ttttctagca
    47821 cttgtatggt aaaatagata caggtgttca ttaaactaga ctaaaaacct atttaagcag
    47881 gcaaaatgaa gaaataccaa caattattta agcaaatcca agaaaccatt caaaacgaga
    47941 cttacgctgt cggagatttc cttcctagcg agcacgacct tatggagcaa tatcaagtga
    48001 gtcgtgatac cgtccgaaag gccctgtctc tcctccaaga ggaaggattg atcaaaaaga
    48061 taagagggca aggttctcaa gtcgtcaaag aagaaaccgt caatttccct gtatccaacc
    48121 taaccagcta ccaagaacta gttaaagaac ttggactgcg ctctaaaacc aacgtggtca
    48181 gtctggacaa gattattatt gataaaaaat cctcactgat aaccggtttc ccagagtttc
    48241 ggatggtttg gaaggtggtc cgccagcgtg tggtggatga tctggtatcc gttctggata
    48301 cggactatct ggatatggaa ctcatcccaa atctcactcg ccaaattgct gagcagtcta
    48361 tctattctta tatagaaaat ggcctcaaac tccttattga ttatgctcag aaggaaatca
    48421 ccattgacca ctcaagcgac cgagacaaga ttctcatgga cattggcaaa gacccttatg
    48481 tcgtttcgat taaatcaaaa gtctatctcc aagacgggcg ccaatttcag tttaccgaaa
    48541 gtcgccataa gttagaaaaa tttagatttg tagattttgc aaaacgcaag aaataaaaga
    48601 ctgagacacc agatctcagc ctttttcttt atcccaaaac taattcatca ctgaccagac
    48661 tttggccact atttttctgg aagagatgca taaggtcttc aactgtcaga tgctttttct
    48721 cttctccctt gacatccacc actatcttgc cttgatagag cataatgaga cgattgccgt
    48781 actcaatcgc atgattcata tcatgggtaa tcatcaaagt cgtccactga tggtactcca
    48841 caatcttttg cgtcaagtcc atcaccattt gactggtttt cgggtcaagt gccgcagtat
    48901 gttcatccaa aagcaaaagt ttgagtttca ccagagctgc catgactagg gtcaaagcct
    48961 gtctttgtcc tcctgagaga tattgagtat ctacttttaa gcggttttca agaccaatat
    49021 tcaactcctt caaggcctct tggaactgga ttctatcctt ctccttcacg ccccaaccaa
    49081 gccctctctt ttgcccacgt ctcaaggcaa tagccatatt ctcctcaatc gtcaaacgag
    49141 aagctgttcc catcttagga tcttgaaaaa cacgggcaat atccttggct ctctttctga
    49201 cactcagatg tttaatggat ttccctgcca gtagaaggtc cccttcgtcc accgatagat
    49261 taccagccaa gatattcatc aaagtggatt ttcctgctcc atttccacca atcacagaga
    49321 taaaatctcc ctcttcaacc tctaaatcta atcctttgag gacatggttc tcattgaccg
    49381 tccctgcttc aaatgtcttg tgaatatttt caagtgttaa caaacttgcc ataactttct
    49441 cctcctattc atttctcaat ttcagaccac gaatctttaa tctcttttgc aatgctggtg
    49501 caaataaaac caaagcgagc aagattgcat taaagagacg taccaagttt tgatctagat
    49561 ttggaatttc atagatattt aaaataatca aacggtaaac aatagcaccg attccgatgg
    49621 ataataagcg gcctccaatg gtcaagtcgt gtatcaagac ttccgagctc aaaccaacaa
    49681 caatggttcc tgtcccagaa gtcacatctg aaaatccatc attttgggca aacaaggaac
    49741 cacatagggc aatcaaaccg gttgaaatca tgtaaccaac aatcttcatg gtgtttacat
    49801 tgactccatt ggcctcactc atcgggatat tgtccccagt cgaacgcaag accaaaccaa
    49861 tctctgtttt catcaaaagg gtcaaaacca aacaagtaag agacagacta aactaagtga
    49921 gaaaacagct ccttcatttg tcagacccaa gctcgccaac tgtttaaaga cggttgcaga
    49981 atctcccaag gaaagattgg gtacactgcc catgatttta atattgattg aatagagccc
    50041 tgtcaaggtc acaatccctg tcaagagagc tgggattttc atcttggtgt ggagcattcc
    50101 tgatataaga cctgctacca tacctgccag caaagcaagt aaagtcgcaa gccaaggatt
    50161 tgcccctgcc tgtatctgtg atacaacgat tgctgccccc ataggaaagg ctccctcagc
    50221 agtcatatcc gcaatatcca aaatacggaa agtcaagtag accccaattg ccataatcga
    50281 ccacaacaaa ccttctgata aactagataa cacaaaattc atcttaatcc tccttattcc
    50341 ttgccttcta acttactaat atcaattcac aatgcatctg ccatttcttg attagtatgc
    50401 aattccagtt tttcaggcaa ctcaactgct atattttctg gttcctcacc ttttaaaaca
    50461 cgaatcagca tgcgagctgt ctgtcttccc aattcttcat aattggttcc gtagttatac
    50521 aagccaccaa cagcaatcat ttctgttgaa ccaccgaata ctggaacctt gtgtttaata
    50581 gaaacctgct taactgtttc catggttgac gaaatgatat tatcagttgg gacaaaaacc
    50641 atatccacct ctgccatcaa actctctgct gccgccttga cgttattact gtccaagatt
    50701 gttttttcaa caacggtaaa gcctttttct ttcagaaatc gcttagcttc atccttttaa
    50761 acaaccgaat tgggctcgct ctgagtatag aggattccaa tcgttttagc ctttagcaac
    50821 actttcttta tcaaattgat ttgggttgaa atggcatctg atgactgatc gcttgtccca
    50881 gttacattgc ccccaggatg ttctcttgac tcaaccaact tggcactgac tgggtctgtt
    50941 acagctgaaa agataactgg tgtcgtttgc gtcgtattgg ccaagctctg agcagaaggc
    51001 cttgcgatgg ctagaacgac atcgctggat tctgctagtt gctgggaaat cgtttttaga
    51061 tttctttgtt ctccctgtgc attttgcaaa tcaatctcaa tattttcccc ctcaacatag
    51121 ccttgtttgg ccagctcatc cacaaatcct tctctagtag cgtctaagga ctggtgggta
    51181 ataaactgcg aaataccgat acgaaagaca tctcttttct tatctgcctt caactgatgc
    51241 aaactgatca gagaagtcaa gaggatcccc actaccaaga gggggctagt gattttcgaa
    51301 caactttcat aatgaaactc cttctcagaa aagataaaac aaaaaaacgc ctagatacta
    51361 tctaaacggg tacttgaaat aacctaacaa gttacaactt agctggtcca tttagatatt
    51421 catctatatg gaccacaatc aaaaatctta gccacataga tacaaacaaa ttgcttgaac
    51481 tgtttgcatc catggtgaca tgtctacaaa cactatctaa agtagctaaa gtaaaagttt
    51541 tgattcatag ttacggcttg tctcttattc atttcttttt ctgctttctt ttttgatcct
    51601 tcctatccta ccaccttttt catcacctgt caataatatt tcaaaatttt ttaaaatttt
    51661 tcgaaaattc tttcag
//
LOCUS       DAVBBO010000006        50102 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ST1
            SAMEA2066453-rid20184263.denovo.006, whole genome shotgun sequence.
ACCESSION   DAVBBO010000006 DAVBBO010000000
VERSION     DAVBBO010000006.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2066453
            Sequence Read Archive: ERR351777
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 50102)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 50102)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980402.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980402.1
            Genome Coverage       :: 176x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:17:33
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,141
            CDSs (total)                      :: 2,104
            Genes (coding)                    :: 1,953
            CDSs (with protein)               :: 1,953
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 16S)
            partial rRNAs                     :: 1 (23S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 151
            CDSs (without protein)            :: 151
            Pseudo Genes (ambiguous residues) :: 0 of 151
            Pseudo Genes (frameshifted)       :: 73 of 151
            Pseudo Genes (incomplete)         :: 76 of 151
            Pseudo Genes (internal stop)      :: 40 of 151
            Pseudo Genes (multiple problems)  :: 32 of 151
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..50102
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2066453-rid20184263.denovo.006"
                     /strain="ST1"
                     /db_xref="taxon:1313"
     gene            <1..746
                     /locus_tag="VQU30_000359"
     CDS             <1..746
                     /locus_tag="VQU30_000359"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001042398.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HET2446538.1"
                     /translation="YELYKDKNYNKQEYYKSGGKTVLETLRKRFGLKDYVSPTEIDTD
                     KKFVFIIDEINRGEISKIFGELFFSIDPGYRGEKGSVSTQYANLHETDEKFYIPENVY
                     IIGTMNDIDRSVDTFDFAMRRRFRFVEVTAEGQVGMLDKELNIHAEEAKIRLRNLNAA
                     IENVQELNSHYHIGPSYFLKLKDVDFDYELLWSDYIKPLLEDYLRGSYDEVETLETLK
                     KAFELTNNEQKDQAVADDNESDENDDADY"
     gene            733..2085
                     /locus_tag="VQU30_000360"
     CDS             733..2085
                     /locus_tag="VQU30_000360"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001223073.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="McrC family protein"
                     /protein_id="HET2446539.1"
                     /translation="MRITDNQHKIIKEKFVEEYPKLSNLLLDRTLESLSQDERIFIFP
                     NDLTHTPDLDKKQKILETINQEIKTGNVIGFLGYGQERLTISSRFSDESNDHFLHYLL
                     NKVLHINLTSLDVALSREERLYQLLMYLFPKYLQAAIRKGLYKEYHRFSHNDSHVKGV
                     IDVRNHLKKNLPFTGNIAYTTREFTYDNPLMQLVRHTIEYIKNQKSIGQGVLDNLSTS
                     RENVSEIVRVTPSYKLADRAKIIRGNQSKPIRHAYFHEYRNLQELCLMILNQEKHGLG
                     YQDQKIYGILFDVAWLWEEYVYTLLPKGFVHPRNKDKTDGISVFSVGKRKVYPDFYDR
                     ERKIVLDAKYKKLELTEKGINREDLFQLISYSYILKAEKAGLVFPSKDKVIDNEMGNL
                     AGYGALLKKWSIQIPQKSSSYSAFCKMMENSDYSAFCKMMENSEENFKAIIDEEVGRK
                     "
     gene            2260..3246
                     /locus_tag="VQU30_000361"
     CDS             2260..3246
                     /locus_tag="VQU30_000361"
                     /EC_number="1.7.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007516839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GMP reductase"
                     /protein_id="HET2446540.1"
                     /translation="MLNEFPIFDYEDIQLIPNKCVIKSRAEADTSVTLGNHTFKLPVV
                     PANMQTILDENVAEQLAKGGYFYIMHRFDEAGRIPFIKQMHDQGLIASISVGVKDYEY
                     DFVSQLKTDAPEYITIDIAHGHADSVISMIQHIKKELPDTFVIAGNVGTPEAVRELEN
                     AGADATKVGIGPGKVCITKVKTGFGTGGWQLAALRWCAKAARKPIIADGGIRTHGDIA
                     KSIRFGASMIMIGSLFAGHIESPGKTIEVDGEQFKEYYGSASQYQKGAYKNVEGKRIL
                     LPAKGHLQDTLTEMEQDLQSAISYAGGRQVADLKHVDYVIVKNSIWNGDASH"
     gene            3310..3381
                     /locus_tag="VQU30_000362"
     tRNA            3310..3381
                     /locus_tag="VQU30_000362"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:3343..3345,aa:Arg,seq:ccg)
     gene            3564..4262
                     /locus_tag="VQU30_000363"
     CDS             3564..4262
                     /locus_tag="VQU30_000363"
                     /EC_number="3.1.26.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007522086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease III"
                     /protein_id="HET2446541.1"
                     /translation="MKELQTVLKNHFAIEFADKNLLETAFTHTSYANEHRLLKISHNE
                     RLEFLGDAVLQLLISEYLYKKYPKKPEGDLSKLRAMIVREESLAGFARDCQFDQFIKL
                     GKGEEKSGGRNRDTILGDAFEAFLGALLLDKDVAKVKEFIYQVMIPKVEAGEFEMITD
                     YKTHLQELLQVNGDVAIRYQVISETGPAHDKVFDVEVLVEGKSIGQGQGRSKKLAEQE
                     AAKNAVEKGLDSCI"
     gene            4253..7792
                     /gene="smc"
                     /locus_tag="VQU30_000364"
     CDS             4253..7792
                     /gene="smc"
                     /locus_tag="VQU30_000364"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000280891.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chromosome segregation protein SMC"
                     /protein_id="HET2446542.1"
                     /translation="MYLKEIEIQGFKSFADKTKVVFDQGVTAVVGPNGSGKSNITESL
                     RWALGESSVKSLRGGKMPDVIFAGTESRKPLNYASVVVTLDNHDGFIKDAGQEIRVER
                     HIYRSGDSEYKIDGKKVRLRDIHDLFLDTGLGRDSFSIISQGKVEEIFNSKSEERRAI
                     FEEAAGVLKYKTRRKETESKLQQTQDNLDRLEDIIYELDNQIKPLEKQAENARKFLDL
                     EGQRKAIYLDVLVAQIKENKAELESTEEELAQVQELLMSYYQKREKLEEENQTLKKQR
                     QDLQAEMAKDQGSLMDLTSLISDLERKLALSKLESEQVALNQQEAQARLAALEDKRNS
                     LSKEKSDKESSLALLEGNLVQNNQKLNRLEAELLAFSDDPDQMIELLRERFVALLQEE
                     ADVSNQLTRIENELENSRQLSQKQADQLEKLKEQLAIAKEKASQQKEELETAKEQVQK
                     LLADYQAIAKEQEEQKTSYQAQQSQLFDRLDNLKNKQARAQSLENILRNHSNFYAGVK
                     SVLQEKDRLGGIIGAVSEHLTFDMHYQTALEIALGASSQHIIVEDEESATKAIDFLKR
                     NRAGRATFLPLTTIKARTISSQNQDAITVSPGFLGMADELVTFDTRLEAIFKNLLATT
                     AIFDAVEHARAAARQVRYQVRMVTLDGTELRTGGSYAGGANRQNNSIFIKPELEQLQK
                     EIAADEASLRSEEAALKTLQDQMATLTERLEVIKSQGEQARIQEQGLSLAYQQTSQQV
                     EELETLWKLQEEEIDRLSEGDWQADKEKCQDRLAAIASDKQNLEAEIEEIKSNKNAIQ
                     ERYQNLQEELAQARLLKTELQGQKRYEVADIERLGKELDNLDFEQEEIQRLLQEKVDN
                     LEKVDTELLSQQAEEAKTQKTNLQQGLIRKQFELDDIEGQLDDIASHLDQARQQNEEW
                     IRKQTRAEAKKEKVSERLRYLQSQLTDQYQISYTEALEKAHELENLNLAEQEVQDLEK
                     AIRSLGPVNIEAIDQYEEVHNRLDFLNSQRDDILSAKNLLLETITEMNDEVKDRFKST
                     FEAIRESFKVTFKQMFGGGQADLILTEGDLLTAGVEISVQPPGKKIQSLNLMSGGEKA
                     LSALALLFSIIRVKTIPFVILDEVEAALDEANVKRFGDYLNRFDKDSQFIVVTHRKGT
                     MAAADSIYGVTMQESGVSKIVSVKLKDLESIEG"
     gene            7789..8583
                     /locus_tag="VQU30_000365"
     CDS             7789..8583
                     /locus_tag="VQU30_000365"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000153012.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HET2446543.1"
                     /translation="MTIKLVATDMDGTFLDGNGRFDMDRLKSLLASYKEKGIYFAVAS
                     GRGFLSLEKLFAGVRDDIIFIAENGSLVEYQGQDLYEATMSRDFYLATFEKLKTSPYV
                     DINKLLLTGKKGSYVLDTVDETYLKVSQHYNENIQKVASLEDITDDIFKFTTNFTEET
                     LEAGETWVNDNVPGVKAMTTGFESIDIVLDYVDKGVAIVELAKKLGITMDQVMAFGDN
                     LNDLHMMQVVGHPVAPENARPEILELAKTVIGHHKDQSVIAYMEGL"
     gene            8583..9401
                     /locus_tag="VQU30_000366"
     CDS             8583..9401
                     /locus_tag="VQU30_000366"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016465979.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HET2446544.1"
                     /translation="MADIKLIALDLDGTLLTTDKRLTDRTKATLKAASDRGIKVVLTT
                     GRPLKAMDFFLHELGTDGHEDEYTITFNGGLVQKNTGEILDKTVFSYDDVARLYEETE
                     KLSLPLDAISEGTVYQIQSDQESLYAKFNPALTFVPVDFEDLSSQMTYNKCVTAFAQE
                     PLDAAIQKISPELFDQYEIFKSREMLLEWSPKNVHKATGLAKLISHLGIDQSQVMACG
                     DEANDLSMIEWAGLGVAMQNAVPEVKAAANVVTPMTNDEEAVAWAIEEYVLKEN"
     gene            9405..10625
                     /gene="ftsY"
                     /locus_tag="VQU30_000367"
     CDS             9405..10625
                     /gene="ftsY"
                     /locus_tag="VQU30_000367"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000522312.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal recognition particle-docking protein
                     FtsY"
                     /protein_id="HET2446545.1"
                     /translation="MGLFDRLFGKKEEPKIEEVVKEALENLDLSEDVDPTFTEVEEVS
                     QEEAVLEESQDSEPAVGVSQEEIEELPEEEKLEHEGTIEENNSEVLEAERPQTEETVQ
                     EKYDRSLKKTRTGFGARLNAFFANFRSVDEEFFEELEELLIMSDVGVQVASNLTEELR
                     YEAKLENAKKPDALRRVIIEKLVELYEKDGSYDESIHFQDNLTVMLFVGVNGVGKTTS
                     IGKLAHRYKRAGKKVMLVAADTFRAGAVAQLAEWGRRVDVPVVTGPEKADPASVVFDG
                     MERAVAEGIDILMIDTAGRLQNKDNLMTELEKIGRIIKRVVPEAPHETFLALDASTGQ
                     NALVQAKEFSKITPLTGIVLTKIDGTARGGVVLAIREELNIPVKLIGFGEKIDDIGEF
                     NSENFMKGLLEGLI"
     gene            complement(10671..12158)
                     /locus_tag="VQU30_000368"
     CDS             complement(10671..12158)
                     /locus_tag="VQU30_000368"
                     /EC_number="1.1.1.49"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000096131.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-6-phosphate dehydrogenase"
                     /protein_id="HET2446546.1"
                     /translation="MSSKVIVTIFGASGDLAKRKLYPSLFRLYQSGNLSKHFAVIGTA
                     RRPWSKEYFESVVVESILDLADSTEQAQEFASHFYYQSHDVNDSEHYIALRQLQAELN
                     EKYQAEHNKLFFLSMAPQFFGTIAKHLKSENIVDGKGFERLIVEKPFGTDYATASKLN
                     DELLATFDEEQIFRIDHYLGKEMIQSIFAVRFANLIFENVWNKDFIDNVQITFAERLG
                     VEERGGYYDQSGALRDMVQNHTLQLLSLLAMDKPAIFTKDEIRAEKIKVFKNLYHPTD
                     EELKEHFIRGQYRSGKIDGMKYISYRSEPNVNPESTTETFTSGAFFVDSDRFRSVPFF
                     FRTGKRLTEKGTHVNIVFKQMDSIFGEPLAPNILTIYIQPTEGFSLSLNGKQVGEEFN
                     LAPNSLDYRTDATATGASPEPYEKLIYDVLNNNSTNFSHWDEVGASWKLIDRIEELWA
                     ENGAPLHDYKAGSMGPQASFDLLEKFGAKWTWQPDIAYRQDGRFE"
     gene            complement(12307..13047)
                     /locus_tag="VQU30_000369"
     CDS             complement(12307..13047)
                     /locus_tag="VQU30_000369"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004254183.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HET2446547.1"
                     /translation="MAKLKIDVNDLHKHYGKNEVLKGITTKFYEGDVVCIIGPSGSGK
                     STFLRSLNLLEEVTSGHITVNGYDLTEKTTNVDHVRENIGMVFQHFNLFPHMSVLDNI
                     TFAPIEHKLMTKEEAEELGMELLEKVGLADKANANPDNLSGGQKQRVAIARGLAMNPD
                     IMLFDEPTSALDPEMVGDVLNVMKELAEQGMTMIIVTHEMGFARQVANRVIFTADGEF
                     LEDGTPDQIFDNPQHPRLKEFLDKVLNV"
     gene            complement(13047..15212)
                     /locus_tag="VQU30_000370"
     CDS             complement(13047..15212)
                     /locus_tag="VQU30_000370"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007522057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding
                     protein/permease"
                     /protein_id="HET2446548.1"
                     /translation="MKKKFLAFLLILFPIFSLGIAKAETIKIVSDTAYAPFEFKDSDQ
                     TYKGIDVDIINKVAEIKGWNIQMSYPGFDAAVNAVQAGQADAIMAGMTKTKEREKVFT
                     MSDTYYDTKVVIATTKSHKISKYDQLTGKTVGVKNGTAAQRFLETIKDKYGFTIKTFD
                     TGDLMNNSLSAGAIDAMMDDKPVIEYAINQGQDLHIEMDGEAVGSFAFGVKKGSKYEH
                     LVTEFNQALAEMKKDGSLDKIIKKWTASSSSAVPTTTTLAGLKAIPVKAKYIIASDSS
                     FAPFVFQNSSNQYTGIDMELIKAIAKDQGFEIEITNPGFDAAISAVQAGQADGIIAGM
                     SVTDARKATFDFSESYYTANTILGVKESSNIASYEDLKGKTVGVKNGTASQTFLTENQ
                     SKYGYKIKTFADGSSMYDSLNTGAIDAVMDDEPVLKYSISQGQKLKTPISGTPIGETA
                     FAVKKGANPELIEMFNNGLANLKANGEFQKILDKYLASESSTASTSTVDETTLWGLLQ
                     NNYKQLLSGLGITLALALISFAIAIVIGIIFGMFSVSPYKSLRVISEIFVDVIRGIPL
                     MILAAFIFWGIPNFIESITGQQSPINDFVAGTIALSLNAAAYIAEIVRGGIQAVPVGQ
                     MEASRSLGISYGKTMRKIILPQATKLMLPNFVNQFVIALKDTTIVSAIGLVELFQTGK
                     IIIARNYQSFKMYAILAIFYLVIITLLTRLAKRLEKRIR"
     gene            15385..16338
                     /locus_tag="VQU30_000371"
     CDS             15385..16338
                     /locus_tag="VQU30_000371"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000792120.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HET2446549.1"
                     /translation="MKNKRIFKDFQASKMNLNLYTSPLLAFVFVFIGEFVAYTLYGIS
                     LLALIGLARNFGEAGQNLASYLQTLHQSLTDKTSDFRLILGLLAFGFILNTVFRWTRK
                     VEKRPIRTLGFYRENCLSNLLKGFSLGLALFLLTLLSLVVLGQYRLESIHLNPYYLAF
                     VVFTIPFWILQGTAEEVVARAWLLPQLASRTNLKLAILISSLFFTLLHMGNSGLTPLS
                     LVNLFLFGVAMALYLLKTDTVWGVAGIHGAWNFAQGNLFGILVSGQPSGTSLMTFLPQ
                     GNQDWLSGGSFGIEGSIMTSLVLLLLIVYLANKLKKENERM"
     gene            16415..18403
                     /gene="uvrB"
                     /locus_tag="VQU30_000372"
     CDS             16415..18403
                     /gene="uvrB"
                     /locus_tag="VQU30_000372"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004254186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit B"
                     /protein_id="HET2446550.1"
                     /translation="MINHITDNQFKLVSKYQPSGDQPQAIEQLVDNIEGGEKAQILMG
                     ATGTGKTYTMSQVISKVNKPTLVIAHNKTLAGQLYGEFKEFFPENAVEYFVSYYDYYQ
                     PEAYVPSSDTYIEKDSSVNDEIDKLRHSATSALLERNDVIVVASVSCIYGLGSPKEYA
                     DSVVSLRPGLEISRDKLLNDLVDIQFERNDIDFQRGRFRVRGDVVEIFPASRDEHAFR
                     VEFFGDEIDRIREVEALTGQVLGEVDHLAIFPATHFVTNDDHMEVAIAKIQAELEEQL
                     AVFEKEGKLLEAQRLKQRTEYDIEMLREMGYTNGVENYSRHMDGRSEGEPPYTLLDFF
                     PDDFLIMIDESHMTIGQIKGMYNGDRSRKEMLVNYGFRLPSALDNRPLRREEFESHVH
                     QIVYVSATPGDYENEQTETVIEQIIRPTGLLDPEVEVRPTMGQIDDLLGEINARVEKN
                     ERTFITTLTKKMAEDLTDYFKEMGIKVKYMHSDIKTLERTEIIRDLRLGVFDVLVGIN
                     LLREGIDVPEVSLVAILDADKEGFLRNERGLIQTIGRAARNSEGHVIMYADTVTQSMQ
                     RAIDETARRRKIQMAYNEEHGIVPQTIKKEIRDLIAVTKAVAKEEDKEVDINSLNKQE
                     RKELVKKLEKQMQEAVEVLDFELAAQIRDMMLEVKALD"
     gene            18413..18976
                     /locus_tag="VQU30_000373"
     CDS             18413..18976
                     /locus_tag="VQU30_000373"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000639844.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HET2446551.1"
                     /translation="MIYLRKLKREDLMSLWEMAYSQLNPVWKQYDAPYYDDYQYFSNF
                     KEFELQKSESILSNSNRLGIFVDDKLVGTVSRYWVCKQTRWMELGIGIYDKKFWNTGI
                     GKVAMLQWIDRTFQDYLELEHLGLTTWSGNLGMMKLAEKLRMKKEAHIPKVRYYQGKY
                     FDSIKYGILREDWEKTNDGYYQINGNS"
     gene            18942..19430
                     /locus_tag="VQU30_000374"
     CDS             18942..19430
                     /locus_tag="VQU30_000374"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004254187.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HET2446552.1"
                     /translation="MTVIIKSMETPEEIEGKPLVHWQTWREAYDGLLPAEFQETMTLE
                     RCRFFSQKYPENTLIAMDGMKVVGFISYGNFRDETIQAGEIIALYVLKDYYGKGIAQK
                     LIKAALIALNHFSEIFLWVLKDNKRAIAFYQKMGFTFDEQEKILELGKPIKEKRMVFY
                     SK"
     gene            19503..19970
                     /locus_tag="VQU30_000375"
     CDS             19503..19970
                     /locus_tag="VQU30_000375"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000085289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="8-oxo-dGTP diphosphatase"
                     /protein_id="HET2446553.1"
                     /translation="MSRAQLTILTNICLIEDLEAQRVVMQYRAPETNRWSGYAFPGGH
                     VENGESFAESVIREIYEETGLTIQNPQLVGIKNWPLDTGGRYIVVCYKATEFSGTLRS
                     SDEGEVSWVQKDQIPNLDLAYDMLPLMEMMEASDKSEFFYPRRTEDDWEKKIF"
     gene            complement(19967..20482)
                     /locus_tag="VQU30_000376"
     CDS             complement(19967..20482)
                     /locus_tag="VQU30_000376"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007522046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription repressor NadR"
                     /protein_id="HET2446554.1"
                     /translation="MTKDRKQALLQLLKEAPKALNGQSLAEHFHVTRQVIVQDIAILR
                     ADGAPILSTNRGYIYKQIDTNPYVHKLFKVKHEVEEIGQELLAIVDNGGHVQNTLIDH
                     PVYGEIETLLKLSCRRDVQHFLEQVEHSDFKPLSELTDGVHYHLVEAETQQDLHYIEE
                     ALDQLGYLVKD"
     gene            complement(20494..21021)
                     /locus_tag="VQU30_000377"
     CDS             complement(20494..21021)
                     /locus_tag="VQU30_000377"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HET2446555.1"
                     /translation="MNTRKKTQFMTMTALLTAIAILIPIVMPFKIVIPPASYTLGSHI
                     AIFIAMFLSPLMAVFVILASSFGFLMAGYPMVIVFRAFSHISFGALGSLYLQKFPDTL
                     DKPKSSWVFNFVLAVVHALAEVLACVLFYATSGTNVENMFYVLFVLVGFGTIIHSMVD
                     YTLALAVYKVLRKRR"
     gene            complement(21299..21862)
                     /locus_tag="VQU30_000378"
     CDS             complement(21299..21862)
                     /locus_tag="VQU30_000378"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000747407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HET2446556.1"
                     /translation="MKKRSNIAPIAIFFATMLVIHFLSSLIFNLFPFPIKPTIVHIPV
                     IIASIIYGPRVGVTLGFLMGLLSLTVNTITILPTSYLFSPFVPNGNIYSAIIAIVPRI
                     LIGLTPYLVYKLMKNKTGLILAGALGSLTNTIFVLGGIFFLFGNVYNGNIQLLLATVI
                     STNSIAELVISAILTLAIVPRLQTLKK"
     gene            complement(21846..22397)
                     /gene="coaC"
                     /locus_tag="VQU30_000379"
     CDS             complement(21846..22397)
                     /gene="coaC"
                     /locus_tag="VQU30_000379"
                     /EC_number="4.1.1.36"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001284124.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopantothenoylcysteine decarboxylase"
                     /protein_id="HET2446557.1"
                     /translation="MANILLAVTGSIASYKSADLVSSLKKQGHQVTVLMTQAATEFIQ
                     PLTLQVLSQNPVHLDVMKEPYPDQVNHIELGKKADLFIVVPATANTIAKLAHGFADNM
                     VTSTALALPSHIPKLIAPAMNTKMYDHPVTQNNLKTLETYGYQLIAPKESLLACGDHG
                     RGALADLTIILERIKETIDEKTL"
     gene            complement(22409..23098)
                     /gene="coaB"
                     /locus_tag="VQU30_000380"
     CDS             complement(22409..23098)
                     /gene="coaB"
                     /locus_tag="VQU30_000380"
                     /EC_number="6.3.2.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000699493.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopantothenate--cysteine ligase"
                     /protein_id="HET2446558.1"
                     /translation="MKILVTSGGTSEAIDSVRSITNHSTGHLGKIITETLLSAGHEVC
                     LITTKRALKPEPHPNLSIREITNTKDLLIEMQERVQDYQVLIHSMAVSDYTPVYMTGL
                     EEVQASSNLKEFLSKQNHQAKISSTDEVQVLFLKKTPKIISLVKEWNPTIHLIGFKLL
                     VDVTEDHLVDIARKSLIKNQADLIIANDLTQISADQHRAIFVEKNQLQTVQTKEEIAE
                     LLLEKIQAYHS"
     gene            23328..24998
                     /locus_tag="VQU30_000381"
     CDS             23328..24998
                     /locus_tag="VQU30_000381"
                     /EC_number="6.3.4.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019803354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate--tetrahydrofolate ligase"
                     /protein_id="HET2446559.1"
                     /translation="MKTDIEIAQSIELKPIVDVVEKLGISYDDLELYGKYKAKLSFDK
                     IRAVESNPVGKLILVTAINPTPAGEGKSTLTIGLADALNKIGKKTMIAIREPSLGPVM
                     GIKGGAAGGGYAQVLPMEDINLHFTGDMHAITTANNALSALIDNHLHQGNELEIDQRR
                     ILWKRVVDLNDRALRHVTVGLGGPLNGIPREDGFDITVASEIMAILCLATDIEDLKRR
                     LANIVIGYRYDRTPVSVGDLQVEGALALILKDAIKPNLVQTIYGTPAFVHGGPFANIA
                     HGCNSVLATTTALHLADYTVTEAGFGADLGAEKFLDIKTPNLPTSPDAVVIVATLRAL
                     KMNGGVAKDALTEENVEAVRAGFANLKRHVENIRKFGIPAVVAINEFVSDTEAEIAVL
                     KELCASIDVPVELASVWADGAEGGVALAETVVKTIAENPANYKRLYDNALSVQEKIEK
                     IVTEIYRGSKVNFEKKAQTQIAQIVQNGWDKLPICMAKTQYSFSDNPNALGAPENFEI
                     TIRELVPKLGAGFIVALTGDVMTMPGLPKRPAALNMDVESDGTVLGLF"
     gene            25326..26501
                     /gene="mutY"
                     /locus_tag="VQU30_000382"
     CDS             25326..26501
                     /gene="mutY"
                     /locus_tag="VQU30_000382"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000886125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="A/G-specific adenine glycosylase"
                     /protein_id="HET2446560.1"
                     /translation="MLDLKEYGIVMWPEEKVISFREKLLAWYDENKRDLPWRRSKNPY
                     HIWVSEIMLQQTRVDTVIPYYERFLDWFPTVESLATAPEESLLKAWEGLGYYSRVRNM
                     QAAAQQIMTDFGGQFPNTYEGISSLKGIGPYTAGAISSIAFNLPEPAVDGNVMRVLAR
                     LFEVNHDIGIPSNRKIFQAMMEILINPDRPGDFNQALMDLGSDIESPVNPRPEESPVK
                     DFSAAYQNGTMDRYPIKSPKKKPVPIYLKALVVKNSQGQFLLEKNESEKLLAGFWHFP
                     LIEVDNFSQEEQFDLFHQVAEESVNFGPSPEESFQQDYDLDVDWLDVCFDTVQHVFSH
                     RKWHVQIVAGQVSDFHDFSDREVRWLSPEEFKNYPLAKPQQKIWQAYAQANLDSSQD"
     gene            26556..27260
                     /locus_tag="VQU30_000383"
     CDS             26556..27260
                     /locus_tag="VQU30_000383"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000722069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HET2446561.1"
                     /translation="MKKILIVDDEKPISDIIKFNMTKEGYEVVTAFNGREALEQFEAE
                     QPDIIILDLMLPEIDGLEVAKTIRKTSSVPILMLSAKDSEFDKVIGLELGADDYVTKP
                     FSNRELQARVKALLRRSQPMPVDGQEADSKPQPIQIGDLEIVPDAYVAKKYGEELDLT
                     HREFELLYHLASHTGQVITREHLLETVWGYDYFGDVRTVDVTVRRLREKIEDTPSRPE
                     YILTRRGVGYYMRNNA"
     gene            27253..28602
                     /gene="vicK"
                     /locus_tag="VQU30_000384"
     CDS             27253..28602
                     /gene="vicK"
                     /locus_tag="VQU30_000384"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000886221.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall metabolism sensor histidine kinase
                     VicK"
                     /protein_id="HET2446562.1"
                     /translation="MLDLLKQTIFTRDFIFILILLGFILVVTLLLLENRRDNIQLKQI
                     NQKVKDLIAGDYSKVLDMQGGSEITNITNNLNDLSEVIRLTQENLEQESKRLNSILFY
                     MTDGVLATNRRGQIIMINDTAKKQLGLVKEDVLNRSILELLKIEENYELRDLITQSPE
                     LLLDSQDINGEYLNLRVRFALIRRESGFISGLVAVLHDTTEQEKEERERRLFVSNVSH
                     ELRTPLTSVKSYLEALDEGALCETVAPDFIKVSLDETNRMMRMVTDLLHLSRIDNATS
                     HLDVELINFTAFITFILNRFDKMKGQEKEKKYELVRDYPINSIWMEIDTDKMTQVVDN
                     ILNNAIKYSPDGGKITVRMKTTEDQMILSISDHGLGIPKQDLPRIFDRFYRVDRARSR
                     AQGGTGLGLSIAKEIIKQHKGFIWAKSEYGKGSTFTIVLPYDKDAVKEEVWEDEVED"
     gene            28604..29413
                     /locus_tag="VQU30_000385"
     CDS             28604..29413
                     /locus_tag="VQU30_000385"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001861619.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HET2446563.1"
                     /translation="MSEIGFKYSILASGSSGNSFYLETSKKKLLVDAGLSGKKITSLL
                     AEINRKPEDLDAILITHEHSDHIHGVGVLARKYGMDLYANEKTWQAMENSKYLGKVDS
                     SQKHIFEMGKTKTFGDIDIESFGVSHDAVAPQFYRFMKDDKSFVLLTDTGYVSDRMAG
                     IVENADGYLIEANHDVEILRSGSYAWRLKQRILSDLGHLSNEDGAEAMIRTLGNRTKK
                     IYLGHLSKENNIKELAHMTMVNQLAQADLGVGVDFKVYDTSPDTATPLTEI"
     gene            29504..29746
                     /locus_tag="VQU30_000386"
     CDS             29504..29746
                     /locus_tag="VQU30_000386"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001853822.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antitoxin"
                     /protein_id="HET2446564.1"
                     /translation="MTTITLKVSEADKTFMKAMAKFEGVSLSELIRTKTLEALEDEYD
                     ARVADLAYQEYLEDLEKGVEPITWEEMMHDLGLKDE"
     gene            29748..30002
                     /locus_tag="VQU30_000387"
     CDS             29748..30002
                     /locus_tag="VQU30_000387"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809704.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
                     /protein_id="HET2446565.1"
                     /translation="MYKLVPTRRFIKQLKKLDRYTQKLITNYLQTNVLEDPRRHGKAL
                     VGNRVGQWRYRIGNYRVIVQIVDDELVVATLEVGHRRDIY"
     gene            30049..30822
                     /locus_tag="VQU30_000388"
     CDS             30049..30822
                     /locus_tag="VQU30_000388"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000731134.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ion transporter"
                     /protein_id="HET2446566.1"
                     /translation="MKKKWFFADYYDTTIILLALISVILVLLGFAEMIDLDNPPYSII
                     DLVIWGVFVIDYSWRFFTTKRKWRFILENIFDLLAILPLNAIFTVFRLGRIFRLAKLT
                     KLLKLTRLLRIIGLTGKLERKISRFLRTNGLIYILYVNIFIVLVGSSILSVVEEKSFS
                     DSLWWALVTVTTVGYGDIVPASIFGKWLAVLLMLVGIGTIGMLTSALTNFFVKDNPDE
                     QIKLDKLKDELSSQRILLEKQSKKIEELHKMIQDLIEKT"
     gene            complement(31082..32068)
                     /locus_tag="VQU30_000389"
     CDS             complement(31082..32068)
                     /locus_tag="VQU30_000389"
                     /EC_number="1.1.1.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019768616.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-lactate dehydrogenase"
                     /protein_id="HET2446567.1"
                     /translation="MTSTKQHKKVILVGDGAVGSSYAFALVNQGIAQELGIIEIPQLH
                     EKAVGDALDLSHALAFTSPKKIYAAQYSDCADADLVVITAGAPQKPGETRLDLVGKNL
                     AINKSIVTQVVESGFKGIFLVAANPVDVLTYSTWKFSGFPKERVIGSGTSLDSARFRQ
                     ALAEKLDVDARSVHAYIMGEHGDSEFAVWSHANIAGVNLEEFLKDTQNVQEAELIELF
                     EGVRDAAYTIINKKGATYYGIAVALARITKAILDDENAVLPLSVFQEGLYGVENVFIG
                     QPAVVGAHGIVRPVNIPLNDAETQKMQASAKELQAIIDEAWKNPEFQEASKN"
     gene            32262..34730
                     /gene="gyrA"
                     /locus_tag="VQU30_000390"
     CDS             32262..34730
                     /gene="gyrA"
                     /locus_tag="VQU30_000390"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003244540.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA gyrase subunit A"
                     /protein_id="HET2446568.1"
                     /translation="MQDKNLVNVNLTKEMKASFIDYAMSVIVARALPDVRDGLKPVHR
                     RILYGMNELGVTPDKPHKKSARITGDVMGKYHPHGDSSIYEAMVRMAQWWSYRYMLVD
                     GHGNFGSMDGDSAAAQRYTEARMSKIALEMLRDINKNTVDFVDNYDANEREPLVLPAR
                     FPNLLVNGATGIAVGMATNIPPHNLGETIDAVKLVMDNPEVTTKDLMEVLPGPDFPTG
                     ALVMGKSGIHKAYETGKGSIALRSRTEIETTKTGRERIVVTEFPYMVNKTKVHEHIVR
                     LVQEKRIEGITAVRDESNREGVRFVIEVKRDASANVILNNLFKMTQMQTNFGFNMLAI
                     QNGIPKILSLRQILDAYIEHQKEVVVRRTRFDKEKAEARAHILEGLLIALDHIDEVIR
                     IIRASETDAEAQAELMSKFKLSERQSQAILDMRLRRLTGLERDKIQSEYDDLLALIAD
                     LADILAKPERVSQIIKDELDEVKRKFSDKRRTELMIGQVLSLEDEDLIEESDVLITLS
                     NRGYIKRLDQDEFTAQKRGGRGVQGTGVKDDDFVRELVSTSTHDHLLFFTNKGRVYRL
                     KGYEIPEYGRTAKGLPVVNLLKLDEDESIQTVINVESDRSDDAYLFFTTRHGIVKRTS
                     VKEFANIRQNGLKALNLKDEDELINVLLAEGDMDIIIGTKFGYAVRFNQSAVRGMSRI
                     ATGVKGVNLREGDTVVGASLITDQDEVLIITEKGYGKRTVATEYPTKGRGGKGMQTAK
                     ITEKNGLLAGLMTVQGDEDLMIITDTGVMIRTNLANISQTGRATMGVKVMRLDQDAQI
                     VTFTTVAVAEKEEVGTENETEGEE"
     gene            34730..35473
                     /gene="srtA"
                     /locus_tag="VQU30_000391"
     CDS             34730..35473
                     /gene="srtA"
                     /locus_tag="VQU30_000391"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000078846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sortase SrtA"
                     /protein_id="HET2446569.1"
                     /translation="MSQKNNKKKNKRKNLLTNILAGFLILLSLALIFNTQIRNIFIVW
                     NTNKYQVSQVSKEKLEENQDTEGNFDFDSVKAISSEAVLTSQWDAQKLPVIGGIAIPE
                     LEMNLPIFKGLDNVNLFYGAGTMKREQVMGEGNYSLASHHIFGVDNANKMLFSPLDNA
                     KNGMKIYLTDKNKVYTYEIREVKRVTPDRVDEVDDRDGVNEITLVTCEDLAATERIIV
                     KGDLKETKDYSQTSDEILTAFNQPYKQFY"
     gene            35717..36514
                     /locus_tag="VQU30_000392"
     CDS             35717..36514
                     /locus_tag="VQU30_000392"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000254803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate/nitrite transporter family protein"
                     /protein_id="HET2446570.1"
                     /translation="MVSSEFISKIEFACNKKESLYSQSKFKYAIRSMFAGAFLTFSTA
                     AGAVGADLINKIAPGSGRFLFPFVFAWGLAYIVFLNAELVTSNMMFLTAGSFLKKISW
                     RKTAEILLYCTLFNLIGALIAGWGFAHSAAYANLTHDSFISGVVEMKLGRSNELVLLE
                     AILANIFVNIAILSFILVKDGGAKLWLVLSAIYMFVFLTNEHIAANFASFAIVKFSVA
                     ADSIANFGVGNMLRHWGVTFIGNFIGGGLLMGLPYAFLNKNEDTYVD"
     gene            36662..36784
                     /locus_tag="VQU30_000393"
     CDS             36662..36784
                     /locus_tag="VQU30_000393"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001855084.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PLP-dependent transferase"
                     /protein_id="HET2446571.1"
                     /translation="MTCDFKFETLQLHAGQVVAPATKSRAVPIYQTTSFIFDDT"
     gene            36806..37846
                     /locus_tag="VQU30_000394"
     CDS             36806..37846
                     /locus_tag="VQU30_000394"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001231001.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="O-acetylhomoserine
                     aminocarboxypropyltransferase/cysteine synthase"
                     /protein_id="HET2446572.1"
                     /translation="MRKPGNIYTRITNPTTAALEGGVEALATASGMTAVTYTILALAH
                     AGDHVVAASTIYGGTFNLLKEPLPRYGITTTFVDVDNLEEVEAAIKDNTKLVLIETLG
                     NSLINIPDLEKLAEIAHKHQIPLVSDNTFAIPYLINVFSHGVDIAIHSATKFIGGHGT
                     TIGGIIVDSGRFDWTASGKFPQFVDEGPSCHNLSYTCDVGAAAFIIAVRVQLLRDTGA
                     ALSPFNAFLLLQRLETSSLRVERHVQNAETIVDFLVNHPKVEKVNYPKLADSPYHALA
                     EKYLPKDVGSIFTFHVKGGEEEARKVIDNLEIFSDLANAADAKSLVVHPATTTHGQLS
                     EKDLEAAGVTPN"
     gene            38017..39291
                     /locus_tag="VQU30_000395"
     CDS             38017..39291
                     /locus_tag="VQU30_000395"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001002592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2130 domain-containing protein"
                     /protein_id="HET2446573.1"
                     /translation="MNEIKCPNCGEVFTVNESQYAELLSQVRTAEFDKELHDRMKQEL
                     ALAEQKAMNEQQTKLAQKDQEIAQLQSQIQNFDTEKELAKKEVEQTSHEALLAKDKEV
                     QLLENQLATLRLEHENQLQKTLSDLEKERDQVKNQLLLQEKENELSLASVKQNYEAQL
                     KAASEQVEFYKDFKAQQSTKAIGESLEQYAESEFNKVRSFAFPNAYFEKDNKVSSRGS
                     KGDFIFRECDENGVEIISIMFEMKNEADGTEKKHKNADFYKELDKDRREKNCEYAVLV
                     TMLEADNDYFNTGIVDVSHEYEKMYVVRPQFFIQLIGLLRNAALNSLKYKQELALVRE
                     QNIDITHFEEDLDAFKLAFAKNYNSASTNFGKAIDEIDKAIKRMEEVKKFLTTSENQL
                     RLANNKLEDVSVKKLTRKNPTMKAKFEALKGE"
     gene            39301..40179
                     /gene="truB"
                     /locus_tag="VQU30_000396"
     CDS             39301..40179
                     /gene="truB"
                     /locus_tag="VQU30_000396"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007516878.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA pseudouridine(55) synthase TruB"
                     /protein_id="HET2446574.1"
                     /translation="MNGIINLKKEAGMTSHDAVFKLRKILGTKKIGHGGTLDPDVVGV
                     LPIAVGKATRMVEFMQDEGKIYEGEIILGYSTTTEDASGEVVAETPVLSPLDEKLVDE
                     AIASLTGPITQIPPMYSAVKVNGRKLYEYARAGQEVERPERQVTIYQFERTSPISYDG
                     QLARFTFRVKCSKGTYIRTLSVDLGEKLGYAAHMSHLTRTSAAGLQLEDALTLEEIAE
                     KVEAGQLDFLHPLEIGTGDLVKVFLTPEEATEVRFGRFIELDQTDKELAAFEDDKLLA
                     ILEKRGNLYKPRKVFS"
     gene            40447..40722
                     /locus_tag="VQU30_000397"
     CDS             40447..40722
                     /locus_tag="VQU30_000397"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000436714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin immunity protein"
                     /protein_id="HET2446575.1"
                     /translation="MEQLLQQKEINENSELSHLFRLAIQNLDRNEKYQSVMANLSQGL
                     SLYLMTHHYQAPKSVIDFGLWIAKAPSQERGRLAFLQMLAQTLQGFR"
     gene            40830..41468
                     /gene="udk"
                     /locus_tag="VQU30_000398"
     CDS             40830..41468
                     /gene="udk"
                     /locus_tag="VQU30_000398"
                     /EC_number="2.7.1.48"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001181378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uridine kinase"
                     /protein_id="HET2446576.1"
                     /translation="MQNRPIIIGVTGGSGGGKTSVSRAILSHFPDEKISMIEHDSYYK
                     DQSHLTFEERVKTNYDHPFAFDTDLMIEQIKELLAGRPVDIPTYDYTEHTRSSKTYRQ
                     EPQDVFIVEGILVLEDKRLRDLMDIKIFVDTDDDVRIIRRIKRDMEERGRSLDSVINQ
                     YLGVVKPMYHQFIESTKRYADIVIPEGVSNTVAIDLLTTKIAKILEEARNSK"
     gene            41596..42936
                     /locus_tag="VQU30_000399"
     CDS             41596..42936
                     /locus_tag="VQU30_000399"
                     /EC_number="3.1.11.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000417449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease VII large subunit"
                     /protein_id="HET2446577.1"
                     /translation="MEKYLSVTTLTKYLKMKFDKDPYLERVYLTGQVSNFRKRPTHQY
                     FSLKDDHAVIQATIWSGIYQKLGFDLEEGMKINVIGRVQVYEPSGSYSIIIEKAEPDG
                     VGALAIQFEQLKKKLTEEGLFQERFKQALPQFSKRIGVVTSRSGAVIRDIITTVSRRF
                     PGVDILLYPTKVQGEGAAEEIARNIARANQRDDLDLLIIGRGGGSIEDLWAFNEEIVV
                     RAIFESRLPVISSVGHETDVTLADFVADRRAATPTAAAELATPVTKLDVLAHLQNQEK
                     RMATAVRNVLSKKQEALKKCSQSVIFRQPERLYDGYLQRLDQLQLRLKQSLRTRISDN
                     KQLVQARTHQLVQLSPVTKIQRYQDRLGQLDKLLGSQMALVYDAKVAEAKRLSEALLM
                     LDTSRIVARGYAIVKKEESVVDSVESLKKKDQVTLLMRDGQVELEVKDVKTKEI"
     gene            42914..43126
                     /locus_tag="VQU30_000400"
     CDS             42914..43126
                     /locus_tag="VQU30_000400"
                     /EC_number="3.1.11.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008809086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease VII small subunit"
                     /protein_id="HET2446578.1"
                     /translation="MSKQKKFEENLAELETIVQSLENGEIALEDAITAFQKGMVLSKE
                     LQATLDKAEKTLVKVMQEDGTESDFE"
     gene            43123..43998
                     /locus_tag="VQU30_000401"
     CDS             43123..43998
                     /locus_tag="VQU30_000401"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000743807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyprenyl synthetase family protein"
                     /protein_id="HET2446579.1"
                     /translation="MKKQEKLALVESALEDFYGDQQFASSLRESVLYSIHAGGKRIRP
                     FLLLEVLESLQVTIKPAHAQVATALEMIHTGSLIHDDLPAMDDDDYRRGRLTNHKKFG
                     EAMAILAGDALFLDPYALIAQADLPSQIKVDLIANLSLASGSLGMVAGQVLDMEGEHQ
                     HLSLEELQTIHANKTGKLLAYPFQAAAIIAELSPEMQVKLKTVGELIGLAFQVRDDVL
                     DVTASFEEIGKTPQKDLQAEKSTYPALLGLEESIAFCNQTLDQANEKLEEIAQQLPFE
                     TESIVSVVESLRING"
     gene            43991..44806
                     /locus_tag="VQU30_000402"
     CDS             43991..44806
                     /locus_tag="VQU30_000402"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001041085.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TlyA family RNA methyltransferase"
                     /protein_id="HET2446580.1"
                     /translation="MAKERVDVLAYKQGLFETREQAKRGVMAGLVVAVLNGERFDKPG
                     EKIPDDTELKLKGEKLKYVSRGGLKLEKALQVFDLSVDGATTIDIGASTGGFTDVMLQ
                     NSAKLVFAVDVGTNQLAWKLRQDPRVVSMEQFNFRYAEKTDFEQEPSFASIDVSFISL
                     SLILPALHSVLADQGQVVALVKPQFEAGREQIGKNGIIRDAKIHQNVLESVTAMAVEA
                     GFSVLGLDFSPIQGGHGNIEFLAYLKKEKSASNQILAEIKEAVERAHSQFKNE"
     gene            44799..45230
                     /locus_tag="VQU30_000403"
     CDS             44799..45230
                     /locus_tag="VQU30_000403"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001034407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine repressor"
                     /protein_id="HET2446581.1"
                     /translation="MNKKERLEKIRRLVTDYQIGTQEEIVEHLKEAGITATQATVSRD
                     IKELGIVKIPLRDNTYVYELPKSIVKSLQLAEDNIESAELMDKMINLQVIPGNTAFVK
                     AQLIETFADKIFSCLTDDSSILVIARSGSLAEEIFEQVKNW"
     gene            45237..46904
                     /gene="recN"
                     /locus_tag="VQU30_000404"
     CDS             45237..46904
                     /gene="recN"
                     /locus_tag="VQU30_000404"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RecN"
                     /protein_id="HET2446582.1"
                     /translation="MLLEISIKNFAIIEAISLNFEKGMTVLTGETGAGKSIIIDAMNM
                     MLGARATTDVIRHGAPKAEIEGLFSVENSRLLQEIFDEQGLELGDEIIIRREILQNGR
                     SISRVNGQMVNLSVLRTIGQHLVDIHGQHDHEELMRPQLHIQMLDEFGDAAFWDLKET
                     YQTSFDAYRKMRKQVLEVKKNQQEHKARIEMLEFQMAEIEAANLQAGEDLDLNQERDK
                     LLNHKNIADTLTNAYSMLDNEDFSSLANVRSAMNDMESVEEYDPEYREISSSLSETYY
                     VLEDISKRLEAIIEDLDFDGNRLMQVENRLDLLHTITRKYGGTVDDVLLYFAKITEEY
                     NLLTGNNLSSEDMEAELKKLEVNLVNLAGQLASARHNLAQQLEAEIKQELQDLYMEKA
                     QFQVRFSKGKFSREGNKMVEFYISTNPGEDFKPLVKVASGGELSRLMLAIKSAFSRKE
                     GKTSIVFDEVDTGVSGRVAQAIAQKIHKIGQHGQVLAISHLPQVIAIADYQFFIEKIS
                     NDHSTVSTVRLLTVEERVEEVAKMLAGDDVTEAALTQARELLRNREK"
     gene            46906..47634
                     /locus_tag="VQU30_000405"
     CDS             46906..47634
                     /locus_tag="VQU30_000405"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000133310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine/threonine protein phosphatase"
                     /protein_id="HET2446583.1"
                     /translation="MTDYYVIGDVHGKAGMLEDLLKTWDGQPQLLFLGDLIDRGEDSH
                     RVLEMVKDLVDNQGAICLSGNHEYMFLTWLDDPEESYDHYSRNGGDTTINSILGRPLD
                     APVDGVEDAKRVAAEAADLVEFIRQMPFVVETDKYIFVHAGIDLTLDDWHETTDYKKV
                     WLRKPFHGAENHTGKTIVFGHTPVYGLLQQERGTSELWTTEDGKIGMDGGAVYGGVLH
                     GIVFTDQGMTEHHFIENDGFVAED"
     gene            47713..49536
                     /gene="lepA"
                     /locus_tag="VQU30_000406"
     CDS             47713..49536
                     /gene="lepA"
                     /locus_tag="VQU30_000406"
                     /EC_number="3.6.5.n1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001047203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor 4"
                     /protein_id="HET2446584.1"
                     /translation="MNLEELKKRQEKIRNFSIIAHIDHGKSTLADRILEKTETVSSRE
                     MQAQLLDSMELERERGITIKLNAIELNYTAKDGETYIFHLIDTPGHVDFTYEVSRSLA
                     ACEGAILVVDAAQGIEAQTLANVYLALDNDLEIMPIINKIDLPAADPERVRTEIEDVI
                     GLDASEAVLASAKAGIGIEEILEQIVEKVPAPTGDVTAPLKALIFDSVYDAYRGVILQ
                     VRVMDGVVKPGDKIQLMSNSKTFDVAEVGIFTPKAVGRDFLATGDVGYIAASIKTVQD
                     TRVGDTVTLATNPAAEPLHGYKQMNPMVFAGLYPIESNKYNDLREALEKLQLNDASLQ
                     FEPETSQALGFGFRCGFLGLLHMDVIQERLEREFNIDLIMTAPSVIYKVNLTDGESMD
                     VSNPSEFPDPTKIATIEEPYVKAQIMVPQEFVGAVMELAQRKRGDFVTMDYIDDNRVN
                     VIYQIPLAEIVFDFFDKLKSSTRGYASFDYELSEYRPSKLVKMDILLNGDKVDALSFI
                     VHKDFAYERGKLIVDKLKKIIPRQQFEVPIQAAIGHKIVARTDIKALRKNVLAKCYGG
                     DVSRKRKLLEKQKAGKKRMKSIGSVEVPQEAFLSVLSMDEE"
     gene            complement(49738..49818)
                     /locus_tag="VQU30_000407"
                     /pseudo
     CDS             complement(49738..49818)
                     /locus_tag="VQU30_000407"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820552.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopuranose mutase"
BASE COUNT        15242 a         8948 c        11370 g        14542 t
ORIGIN      
        1 tttacgagtt gtataaagat aaaaattata ataagcaaga atactacaaa agtggtggaa
       61 aaactgtcct agaaacattg agaaagagat ttggtttgaa agactatgtt tccccaacag
      121 aaattgatac tgataagaaa ttcgttttca tcatcgatga aatcaatcgt ggggagattt
      181 ctaagatttt tggcgaactc tttttctcta tcgaccctgg ctatcgtggt gaaaaaggaa
      241 gtgtttctac ccaatatgca aatctacacg aaactgatga aaagttctat atccccgaaa
      301 atgtttacat catcggaact atgaatgata ttgatcgttc agtggatacc tttgattttg
      361 ctatgcgtcg tcgttttcgt tttgttgaag ttactgccga gggtcaagtt ggcatgttgg
      421 ataaagagct gaatatccat gcagaagaag caaaaattcg tctaagaaac ttgaacgctg
      481 ctatcgaaaa tgttcaggaa ttaaacagtc attatcatat tggaccaagt tattttctta
      541 agttgaagga tgtagatttt gactatgaat tactctggtc cgattatatt aagcctctcc
      601 tagaagacta cttgcgaggt tcttatgatg aggttgaaac tttggaaact ttgaaaaaag
      661 catttgaact gacaaataat gagcaaaaag atcaggcagt agctgatgac aatgaaagcg
      721 atgaaaacga tgatgcggat tactgataat caacacaaga ttattaaaga aaaatttgtt
      781 gaagaatatc ctaaactaag caatcttctt ttagacagaa ccttggaaag tctatcccaa
      841 gatgaacgta ttttcatttt tccaaatgat ttgactcata ctccagattt ggataaaaaa
      901 caaaagattt tggaaacgat caatcaggaa atcaagacag gaaatgtgat tggttttctt
      961 ggatatggtc aggaaagatt aacgatttcc tcacgatttt ctgatgagag taatgaccat
     1021 tttttgcatt atctcttaaa caaggttctt catatcaatc tcactagttt agatgttgct
     1081 ttgtctcgtg aagagaggct ttatcaactt ttgatgtatc tcttccccaa gtatctacaa
     1141 gctgctattc gaaaaggtct ttataaggaa tatcatcgat tttctcataa cgacagtcat
     1201 gttaagggag tgattgatgt aagaaaccat ctcaagaaaa atcttccttt cacgggaaat
     1261 attgcctaca caacgagaga gttcacctat gataatcccc tcatgcagtt ggtccgtcac
     1321 actattgaat acattaagaa tcagaaaagc attggtcaag gggtactaga taatctctca
     1381 actagtcgtg aaaacgtatc tgaaatcgtg cgtgtaacgc cctcttataa actagctgat
     1441 cgtgctaaga ttattcgggg aaatcaatct aaacctatac gtcatgcata ctttcacgag
     1501 tacagaaact tacaagaact ttgtctgatg atcctaaacc aagaaaagca cggtttaggg
     1561 tatcaagatc aaaaaatcta tggtattctc tttgatgttg cctggctttg ggaagagtat
     1621 gtttacacct tgttgccaaa aggttttgta catcccagaa ataaggataa gacggatgga
     1681 atttcagtat tttctgttgg gaaacgaaaa gtatatccag atttttatga cagagaacga
     1741 aagattgttc tagatgcaaa atataaaaaa ctggaattga ctgaaaaagg aatcaatcgt
     1801 gaggacttat tccagctgat ttcctattct tatattttaa aagctgagaa ggctggactt
     1861 gtttttccga gcaaggacaa ggttattgat aatgagatgg gaaacctagc aggttatgga
     1921 gctttgttga agaaatggtc tatccaaatt cctcagaagt cttcatctta tagtgcattt
     1981 tgtaaaatga tggaaaattc agattatagt gcattttgta aaatgatgga aaattcagaa
     2041 gaaaatttta aagcgattat tgatgaagaa gtggggagaa aataatttcc cctctttctt
     2101 ttatttttaa cacaagtaaa acccgaacaa tatatttcaa ttcataaaat aatttgacaa
     2161 aaactgtact ttggtttata ataaattaag gaaacgtcgg aaaagacgta gtgatgcgag
     2221 agcataggta ggtcattaca aaagaaacga gacatcgata tgttaaatga atttccaatt
     2281 tttgattacg aagatattca attgattcca aataaatgtg tcattaaaag ccgtgcagaa
     2341 gcggatacaa gtgtcacttt aggaaatcac acctttaaac tacctgttgt gccagcgaat
     2401 atgcagacga ttttggatga aaatgtagca gagcaactgg ctaaaggtgg ttacttctac
     2461 attatgcacc gttttgatga ggcaggacgc attcctttta ttaaacaaat gcacgatcaa
     2521 gggctcattg cttccatctc tgtcggtgtt aaggactatg agtatgattt tgttagccag
     2581 ctcaagactg atgctcctga gtatatcact attgatattg ctcatggtca tgcggatagc
     2641 gtgatttcta tgattcaaca tatcaagaaa gaattgccag atacctttgt cattgctgga
     2701 aatgtgggaa caccagaagc tgtgcgtgaa ttggaaaatg ctggtgcgga tgctactaag
     2761 gtcggaatcg gtcccggtaa ggtttgtatc accaaggtta agactggttt tggtacaggt
     2821 ggttggcagt tggctgctct acgctggtgt gccaaggctg cgcgtaaacc gattatcgct
     2881 gatggaggaa ttcgtactca cggtgatatt gctaagtcta tccgcttcgg tgctagcatg
     2941 atcatgattg gttccctctt tgcaggacac attgaaagtc cagggaaaac gattgaagtc
     3001 gatggtgaac agttcaaaga atattatggt tcagcctcac aatatcaaaa aggtgcttac
     3061 aaaaatgtgg aaggcaaacg tatcttgctt cctgctaaag gtcatctgca agacacttta
     3121 actgagatgg aacaagacct tcaaagtgct atttcttatg caggtggacg tcaggttgct
     3181 gaccttaaac acgttgatta tgtgatcgtg aaaaactcca tctggaatgg ggatgcttcc
     3241 cactaagacg gggtctttga ccaaaaaact tgttattaga gcaaatttct gttataataa
     3301 aacaagtttc cacccttagt gtaatggata tcacgtaaga ttccggttct tgagatgggg
     3361 gttcgattcc ctcagggtgg atgtaaacat cctaaaaagc ctttaatagg gcttttttct
     3421 ttatcctgac ccaaatttgc cgctaaaact gagaatctct gtctaaagaa ttcccaaatg
     3481 ctttccagtc ccgttttaga gtgactcagg gggctttttt tgatataata aaaaggactg
     3541 ttatcagtta gaaagaggtt ggtatgaaag aattacaaac tgtactaaag aatcattttg
     3601 caatcgaatt tgcagacaaa aatttactgg aaactgcctt tactcatacg agttatgcca
     3661 atgagcaccg cctcttaaaa atttcacaca atgaacgctt ggaattttta ggagacgctg
     3721 ttctacagtt attgatttca gaatatctat ataaaaaata tcctaaaaag cctgaaggtg
     3781 acctatcaaa actccgtgct atgattgtcc gtgaggagag tttagctggt tttgcgcgtg
     3841 attgccagtt tgaccagttt atcaagttgg gtaaagggga agaaaaatca ggtggtcgca
     3901 atcgtgacac cattcttggt gatgcctttg aagcctttct tggtgccctt cttttggata
     3961 aggatgtggc caaggtcaag gaatttatct atcaagtcat gattcctaag gttgaagcag
     4021 gcgaatttga gatgattaca gactataaaa cccatctcca agagttactt caggtcaatg
     4081 gtgatgtggc tattcgttat caggtgattt ctgaaacagg gcctgctcac gataaggtct
     4141 ttgatgtaga agttcttgtt gaaggtaaga gcatcggtca aggccaaggt cgttctaaga
     4201 aattagcaga gcaggaagct gccaaaaatg ccgttgagaa ggggctggat tcatgtattt
     4261 aaaggaaatc gaaattcagg ggttcaagtc ttttgctgat aagaccaagg tcgtttttga
     4321 ccaaggtgtg acggcagttg ttggacccaa tggatctgga aagtccaata ttacagaaag
     4381 tctgcgttgg gctttggggg agtctagtgt caagagtctc cgtgggggca agatgccgga
     4441 tgtcatcttt gctggaacag aaagtcgcaa accgctcaat tatgcttctg tagttgtgac
     4501 tctggataat catgacggat ttatcaagga tgcaggtcaa gaaatcaggg tggaacgcca
     4561 tatctatcgt agtggagata gcgaatacaa gattgacggc aagaaagtcc gtctgcgtga
     4621 tattcatgac cttttcttgg atacaggttt gggacgagat tccttctcta ttatttccca
     4681 agggaaggtt gaggagattt ttaattccaa gtctgaggaa cgacgagcta tttttgaaga
     4741 agctgctgga gttttaaaat acaagactcg cagaaaagaa accgagagta aactgcagca
     4801 aactcaggat aatctggacc gcttagagga cattatctac gagttggata atcaaatcaa
     4861 gcctcttgag aagcaagctg agaatgcccg taaatttcta gacttagaag gtcaacgcaa
     4921 ggctatttac ttggatgtat tggttgctca aatcaaggaa aataaggcag aactagagtc
     4981 gacagaagaa gagttggctc aggttcaaga actcttgatg agttattacc aaaagcgtga
     5041 aaaattagaa gaagaaaatc aaactcttaa aaagcaacgc caagatttac aggctgaaat
     5101 ggccaaagac caaggcagtt tgatggactt gactagtctg attagtgatt tagaaagaaa
     5161 attagcccta tcgaaactgg agtctgagca agtggccttg aatcaacagg aggcacaagc
     5221 tcgtttggct gctttggagg ataagagaaa ttcactcagc aaagaaaagt ctgataaaga
     5281 aagctcttta gctctgttag agggaaatct agtccaaaat aatcaaaaac tcaatcgttt
     5341 agaagctgaa ttgctggctt tctcagacga tcctgatcag atgattgagc tcttacgtga
     5401 acgctttgta gctcttttac aagaagaagc ggatgtctca aaccagttga cccgtattga
     5461 gaatgagttg gaaaatagtc gtcagctttc tcaaaaacaa gcagatcaac tagaaaagct
     5521 gaaagagcaa ttagctatag ctaaagagaa ggctagtcag caaaaggaag agcttgaaac
     5581 tgccaaggag caggttcaga aattattggc tgactaccaa gctattgcca aggagcaaga
     5641 ggagcagaaa acttcctatc aagctcaaca aagccaactc tttgaccgtc tggataatct
     5701 caaaaacaag caggccagag ctcaaagttt ggaaaatatc ctgagaaatc atagtaactt
     5761 ttatgcaggt gttaagagtg ttctccaaga aaaagatcgc ctaggtggga ttattggtgc
     5821 agtcagtgag catctgacct ttgatatgca ttatcaaact gccctagaaa ttgcgcttgg
     5881 agcgagtagc caacatatca tcgtagaaga tgaagagtcg gcaaccaagg ctattgactt
     5941 ccttaaacgg aacagagccg gtcgtgcaac ctttcttcct ttgaccacta tcaaggcgcg
     6001 tacgatttct agtcagaacc aagatgctat cactgtaagc ccaggtttcc ttgggatggc
     6061 agatgagttg gtgacttttg atactagact ggaagccatt ttcaagaact tgctagctac
     6121 gacggctatc tttgatgccg tagaacatgc gcgtgcagca gctcgccaag ttcgttatca
     6181 ggttcgtatg gtgacattgg atgggacaga attacgcacg ggtggttcct atgcgggtgg
     6241 tgccaatcgc caaaataaca gtattttcat caagccagaa ctggagcaat tacaaaaaga
     6301 aattgctgca gatgaagcaa gcttgcgttc agaagaagcg gctttgaaga ccttacaaga
     6361 ccagatggct acattgacag aaagattaga agtcatcaaa tctcaaggag aacaggcacg
     6421 tattcaggag caaggcttgt ccctcgctta tcagcaaact agtcagcaag ttgaagaact
     6481 ggaaactctt tggaaactcc aagaagagga aatagatcgt ctttccgagg gagattggca
     6541 agcggataag gaaaaatgcc aagatcgtct tgctgcaatc gccagtgaca agcaaaatct
     6601 ggaagctgag attgaagaga ttaagtctaa caaaaatgcc atccaagaac gctatcaaaa
     6661 cttgcaggaa gagctagcgc aagctcgttt gcttaagaca gaactgcaag ggcaaaaacg
     6721 ttatgaagtt gctgatattg aacgcttagg caaggaattg gacaatcttg attttgaaca
     6781 agaggaaatc cagcgccttc ttcaagaaaa ggttgataat cttgagaagg ttgatacaga
     6841 attgctcagt caacaggcgg aagaagccaa aactcagaaa acaaatctcc aacaaggttt
     6901 gattcgcaag cagtttgagt tggatgatat tgaaggtcaa ctggatgata ttgctagtca
     6961 tttggatcag gctcgccaac agaatgaaga gtggattcgc aagcaaacac gtgctgaagc
     7021 caagaaagaa aaggtcagcg agcgcttgcg ctatttacaa agtcaattaa cagaccaata
     7081 tcagattagc tatactgaag ctctagaaaa ggcgcatgaa ttggaaaacc tcaatctggc
     7141 agagcaagag gtgcaggatt tagagaaagc tattcgctca ctggggcctg tcaatataga
     7201 agctattgac cagtacgaag aagttcacaa tcgtctggat ttcctaaata gccaacgaga
     7261 tgatattttg tcagcgaaaa atctgctcct tgagaccatt acagagatga atgatgaggt
     7321 caaagatcgc tttaaatcaa cctttgaggc cattcgtgaa tcctttaaag tgaccttcaa
     7381 acagatgttt ggaggaggtc aggcagactt aatcttgact gagggagact tgttgacagc
     7441 tggggttgag atttctgttc aacctccagg taagaaaatc cagtcgctta acctcatgag
     7501 tggtggtgaa aaagccttat cagctcttgc tttgcttttt tctatcattc gagttaagac
     7561 tatcccattt gtcatcttgg atgaggtaga ggccgcgctg gacgaagcca atgttaaacg
     7621 ttttggggat tacctcaatc gatttgacaa ggacagccag tttatcgtcg taacccaccg
     7681 taagggaacc atggcagcgg ctgattctat ctatggagtg accatgcaag aatcgggggt
     7741 ctcaaaaatt gtttcggtta agttaaaaga tttagaaagt attgaaggat gacaattaaa
     7801 ctagtagcaa cggatatgga cggaaccttc ctagatggga atggacgctt tgatatggat
     7861 cgtctcaagt ctctcttggc ttcctacaag gaaaaaggga tttactttgc ggtggcttcg
     7921 ggtcggggat ttctgtctct ggaaaaatta tttgctggtg ttcgtgatga cattattttc
     7981 atcgcggaaa atggcagttt ggtagagtat caaggtcagg acttgtatga agcgactatg
     8041 tctcgtgact tttatctggc aacttttgaa aagctgaaaa cgtcacctta tgtagatatc
     8101 aataaactgc tcttgacggg taagaagggt tcatatgttc tagatacggt tgatgagacc
     8161 tatttgaaag tgagtcagca ttataatgaa aatatccaaa aagtagcgag tttggaagat
     8221 atcacagatg acattttcaa atttacaacc aacttcacag aagaaacgct ggaagctgga
     8281 gaaacttggg taaacgataa tgtccctggt gtcaaggcta tgacaactgg ctttgaatct
     8341 attgatattg ttctggacta tgtcgataag ggagtggcta ttgttgaatt agctaaaaaa
     8401 cttggtatca caatggatca ggtcatggct tttggagaca atcttaatga cttacatatg
     8461 atgcaggttg tgggacatcc tgtagctcct gaaaatgcac gacctgaaat tttagaatta
     8521 gcaaagactg tgattggtca ccataaggac cagtcggtta tagcttatat ggagggctta
     8581 taatggcaga tataaaatta atcgcattgg acttggatgg taccttgctg actactgata
     8641 aaaggctgac ggatcgcacc aaggcaactt tgaaagctgc gagtgatcgt ggtatcaagg
     8701 tcgtattgac aactggtcgt cccttaaaag ccatggactt ctttctccat gagttaggga
     8761 ctgacggcca tgaagatgag tataccatta cttttaatgg tggattagtt cagaaaaata
     8821 caggagaaat ccttgataaa acagtctttt catatgatga tgtggcacgt ttgtatgagg
     8881 aaacagagaa attatcactg cctcttgatg ccatctcaga aggaacagtt tatcaaatcc
     8941 aatcggacca agaaagtctt tatgccaaat tcaatccagc tttgactttt gttccagttg
     9001 actttgaaga cctgtctagt caaatgacct acaacaaatg cgtgactgcc tttgctcaag
     9061 aacccttgga tgcagccatt cagaagattt ctccagaatt gtttgaccaa tatgaaatct
     9121 ttaaatcacg tgaaatgttg ctagaatggt caccaaagaa tgttcataaa gcaacaggtt
     9181 tggcaaaact aattagccat cttggaattg atcaaagtca agtgatggcc tgtggtgacg
     9241 aggccaatga cctctctatg attgaatggg cagggctcgg tgttgccatg caaaacgctg
     9301 ttcctgaagt aaaggcagcc gcaaatgtag tgacgccgat gaccaacgat gaggaagctg
     9361 tcgcctgggc tatcgaagaa tatgtgctaa aggagaacta agatatggga ttatttgacc
     9421 gtctattcgg aaaaaaagaa gaacctaaaa tcgaagaagt tgtaaaagaa gctctggaaa
     9481 atcttgattt gtctgaagat gttgatccta ccttcacaga agttgaagaa gtttctcaag
     9541 aagaagctgt gcttgaagaa agtcaggatt cagagccagc tgtaggggtt tctcaagaag
     9601 aaatagaaga attaccagag gaagagaagc ttgagcacga aggaactata gaagaaaata
     9661 attctgaagt tcttgaagca gaaaggcctc aaacagaaga aactgttcag gaaaaatatg
     9721 accgcagtct taagaaaact cgcacaggtt tcggtgcccg cttgaatgcc ttctttgcta
     9781 acttccgctc tgttgacgaa gaatttttcg aggaactgga agaactgttg attatgagtg
     9841 atgttggtgt ccaagtcgct tctaacttaa cggaggaact acgttacgaa gccaagcttg
     9901 aaaatgccaa gaaacctgat gcacttcgtc gtgtcatcat tgagaaattg gttgagcttt
     9961 atgaaaagga tggtagctac gatgaaagca tccacttcca agataacttg acagttatgc
    10021 tctttgttgg tgtgaatggt gttgggaaaa caacttctat cggaaaacta gcccaccgct
    10081 acaaacgagc tggtaagaag gtcatgctgg ttgcagcaga taccttccgt gcgggtgcag
    10141 tagctcagct agctgaatgg ggccgacgag tagatgttcc agtagtaact ggacctgaaa
    10201 aagctgatcc agccagcgtg gtctttgatg gtatggaacg tgccgtggct gaaggtatcg
    10261 atattctcat gattgatact gctggtcgtc tgcaaaataa ggataacctt atgactgagt
    10321 tggaaaagat tggtcgtatt atcaaacgtg ttgtgccaga agcaccacat gaaaccttct
    10381 tggcacttga tgcatcaaca ggtcaaaatg ccctagtaca ggccaaagaa ttttcgaaaa
    10441 tcacaccttt aacgggaatt gttttgacta agattgatgg aactgctcga ggaggtgtgg
    10501 ttctagccat tcgtgaagaa ctcaatattc ctgtaaaatt gattggtttt ggtgaaaaaa
    10561 tcgatgatat tggagagttt aactcagaaa acttcatgaa aggtctcttg gaaggtttaa
    10621 tctaatcaga agcaaaaatc ctgcaaggca taaacttgca ggaaattttt ttattcgaaa
    10681 cgaccatctt gacgataggc gatatctggt tgccaagtcc atttggcacc gaatttttca
    10741 agtaggtcaa agctggcttg aggtcccatg cttccagctt tatagtcatg aagtggggca
    10801 ccattttcag cccagagctc ttcaatacgg tcaatcaact tccatgatgc accaacttca
    10861 tcccagtggc taaagttagt tgagttgtta tttaggacat cataaatcaa tttctcgtat
    10921 ggttctggag aagcaccagt tgcagtcgca tctgtacggt aatcaagtga gttaggagcc
    10981 aagttaaatt cttctcctac ttgcttccca tttaggctaa gagagaagcc ttctgttggt
    11041 tgaatataga tggtcaaaat atttggagca agtggttctc caaagataga atccatttgt
    11101 ttaaagacga tgttgacatg agttcctttt tcagtcagtc gtttacctgt acggaaaaag
    11161 aaaggaacac tacggaatcg atcgctgtct acaaagaagg caccagatgt aaaggtttca
    11221 gttgttgatt ctggattcac atttggctcg ctacgataag agatgtattt catgccatca
    11281 atcttaccag agcggtattg cccacggata aagtgttctt tgagttcttc atcagttgga
    11341 tgatagaggt ttttaaagac cttaatcttt tcagcacgaa tctcgtcttt tgtgaagatt
    11401 gctggtttgt ccatggcgag gagcgaaaga agttgtagag tgtggttttg gaccatgtca
    11461 cggagggcac cggattggtc atagtagcca ccacgttctt ctacacccaa gcgctccgca
    11521 aaggtaattt gaacattgtc gataaaatcc ttgttccaaa cgttttcaaa aatcaagttt
    11581 gcaaagcgaa ctgcaaagat gctttggatc atttccttac caagataatg gtcgatacgg
    11641 aaaatttgtt cttcgtcaaa tgttgctagg agttcgtcat tcaacttgct tgcagttgcg
    11701 taatctgtac caaatggttt ttcaacgatc aagcgctcaa aacctttgcc atcgacaatg
    11761 ttttcagatt tgaggtgttt ggcaatggtt ccaaagaact gaggtgccat agacaagaag
    11821 aagagcttat tgtgttcagc ttggtatttt tcattaagct cagcttgtaa ttgacgcaaa
    11881 gcaatataat gttccgaatc attgacatca tggctttgat agtagaagtg gctagcaaat
    11941 tcttgggctt gctcggtact atctgccaaa tcaaggatgg actcgacaac tacagattca
    12001 aaatattcct tactccaagg tctacgggca gttccaataa cggcaaagtg cttggaaaga
    12061 ttgccggatt gatatagtct aaaaagggaa gggtagagct tgcgtttagc caggtctcca
    12121 ctcgcaccga aaattgtaac aataacctta gatgacatct agctacctaa tttctatttt
    12181 tattcctagt cttgctaggt atgaggaaac ctcatttcat aaacttaatt ctaacataat
    12241 tttccgaaaa atcaaaaatt ccaatacgag gtagaaaaac tgcaaggaaa tccttacagt
    12301 ttgagtttag acgtttaaga ccttatctaa gaactctttc agacgagggt gttgtgggtt
    12361 atcaaagatt tggtcaggtg ttccgtcttc aaggaactcg ccatctgcag taaagataac
    12421 gcggttggca acctgacgag caaatcccat ctcatgggtt acgataatca tggtcatgcc
    12481 ttgctcagcc aattccttca taacgttaag tacgtctcca accatctcag ggtcaagggc
    12541 agaagttggt tcatcgaaga gcatgatgtc tggattcatt gctaggccac gagcgatggc
    12601 cacacgttgt ttttgaccac ctgataggtt atctggattg gcattagctt tatctgctag
    12661 tccaaccttt tcaagcaact ccattcccaa ttcctcagct tcttccttag tcatcaactt
    12721 gtgctcaata ggagcaaagg tgatgttgtc caatacagac atatgaggga agaggttgaa
    12781 gtgttggaat accatgccga tattttcacg gacgtggtca acattggttg ttttttcagt
    12841 taaatcatag ccgttcacag tgatgtgacc gctagtgact tcttctaaaa gattgaggct
    12901 acggaggaaa gttgacttac cagaacctga aggaccgatg atacaaacaa catctccttc
    12961 atagaactta gtcgtaattc cttttaggac ttcatttttt ccatagtgct tgtgtaaatc
    13021 atttacatca atttttaatt ttgccattaa cgaatcctct tttctaagcg tttcgctagt
    13081 ctagtcaaaa gtgtgataat tacaagatag aagatagcaa ggattgcata catcttgaaa
    13141 ctttggtagt tacgagcaat gataatctta ccagtttgga agagttcaac caaaccgata
    13201 gcagatacga tagttgtatc tttaagagcg ataacgaatt ggttgacaaa gtttggcaac
    13261 atcaatttag ttgcttgtgg caagataatc ttacgcatgg tttttccata agagataccc
    13321 aagcttcggc tggcttccat ttggccaact ggaacggcct gaataccacc acgaacgatt
    13381 tcagcgatat aagcagccgc attgagtgag agggcaatgg ttccagctac aaagtcgtta
    13441 attgggcttt gttggcctgt gatagactcg atgaagtttg gaattcccca gaagatgaag
    13501 gctgcaagaa tcatcaatgg aataccacga ataacgtcaa cgaaaatctc agagatgacg
    13561 cgaagagatt tgtatgggct aacgctaaac ataccgaaga taattccgat gacaatggca
    13621 atagcaaatg agataagagc tagagcaaga gtgataccaa gaccgctaag gagttgtttg
    13681 tagttgtttt gaagcaagcc ccagagcgtt gtttcgtcaa cagtacttgt tgaagcagtt
    13741 gaagattcgc tagctaggta tttgtcaaga atcttttgga attcaccgtt tgctttaagg
    13801 tttgcaagtc cgttgttgaa catttcaatc agttctggat ttgctccttt tttaacggca
    13861 aaggctgttt caccgattgg agttccagag attggagttt tcaatttttg accttggctg
    13921 atagaatatt tgagaacagg ttcatcatcc ataacggcat caatggcacc agtgtttaaa
    13981 ctgtcataca ttgaagaacc atcagcaaag gttttgattt tgtaaccgta tttgctttga
    14041 ttttctgtta ggaaggtttg agaagcagtt ccgtttttaa caccgactgt ctttcctttt
    14101 agatcttcat aagaagcaat attgcttgat tctttgacac caagaatggt attagcagtg
    14161 tagtatgatt ctgagaagtc aaaagttgcc ttacgagcat ctgtgacaga cataccagca
    14221 atgataccat cggcttgacc agcttggaca gcactgatag cagcatcaaa accagggttg
    14281 gtgatttcaa tttcaaaacc ttggtcttta gcgattgcct taatcaattc catatcaata
    14341 ccagtgtatt ggttgcttga attttggaaa acaaaaggtg caaaagaaga atcgctggca
    14401 atgatatatt tagccttaac aggaatagct tttaatcctg cgagagtagt tgtagttggc
    14461 actgctgaag atgatgaagc agtccatttc ttgataattt tatcaagact accatctttt
    14521 ttcatttcag ccaaggcttg gttaaattca gtaaccaggt gctcgtattt acttcctttt
    14581 ttcacaccga aagcaaaact tcctacagct tcaccatcca tttcaatatg gaggtcttga
    14641 ccttggttaa tggcatattc gataacaggt ttgtcatcca tcatggcatc gatggcacca
    14701 gcactcaagc tgttgttcat taaatcacca gtgtcaaatg ttttaatagt aaagccgtat
    14761 ttatctttga ttgtttcaag gaaacgttga gcggcagttc cgtttttaac accaacggtt
    14821 ttgccagtta attggtcgta cttgctaatt ttgtgtgact ttgtagtagc aatgacaact
    14881 tttgtatcat agtaagtatc agacatggtg aagacttttt cacgttcttt agtctttgtc
    14941 atccctgcca tgatagcgtc ggcttgccca gcttgaaccg cattgactgc tgcgtcaaat
    15001 ccaggatagg acatctgaat gttccagcct ttaatctcag cgactttgtt aataatgtca
    15061 acatcaattc ctttataagt ttgatctgaa tctttaaact caaaaggtgc ataggcggta
    15121 tcagaaacaa tcttaatcgt ttctgctttg gcaataccta atgagaaaat tgggaataaa
    15181 attagcaaaa atgctagaaa ttttttcttc atttttagtc tccttttccg aatattctct
    15241 cattatatca gaaaaagtaa aaaaaggcaa atttttatat ttttcgtgtc agaaaatata
    15301 acattgattt ttccttttct ttcttgaatt gctattaaaa attgctataa taatactata
    15361 tatagaagaa aagaggacgg ggatatgaag aacaaaagaa tatttaaaga cttccaagct
    15421 tcaaaaatga atttaaacct ttacacaagc cccttgttag cctttgtttt tgtcttcata
    15481 ggagagtttg tggcttatac tttatatggt attagtttgt tagctctcat cggacttgct
    15541 agaaattttg gagaggctgg tcaaaatctt gcaagctact tgcagacctt gcatcagagc
    15601 ttgacggata aaacaagtga ctttcgttta attttaggat tactggcctt tggttttatt
    15661 cttaacactg tgttcagatg gacaagaaaa gttgagaaaa gacctattcg aaccttggga
    15721 ttttatagag agaattgcct cagcaatctt ctgaaaggat ttagtctagg cctggcactt
    15781 tttcttctga ccttgttaag tttagtggtc ttaggtcaat atcgtttgga atccattcac
    15841 ttgaatcctt attatcttgc ctttgtcgtc tttactatcc cattttggat tttacagggg
    15901 acagcagaag aagtggtggc ccgtgcttgg ctacttcctc aattggcctc aagaaccaat
    15961 ctaaaactag ctattcttat atctagcctg ttctttaccc tgcttcatat gggcaattct
    16021 ggcctcaccc ctctatctct agtaaatctc tttttattcg gagttgccat ggctctttac
    16081 cttctcaaaa ctgatacagt ttggggtgtt gcaggtattc atggtgcttg gaattttgct
    16141 cagggtaatc tctttgggat tttagttagt ggtcaaccgt caggaacgtc tctgatgacc
    16201 tttttaccac aaggcaatca agattggcta tcaggtggtt cttttggcat agaaggttcc
    16261 attatgacaa gtctggtatt actactgctg attgtctatc ttgctaataa attaaagaaa
    16321 gaaaatgaaa ggatgtgact tcggtccgtc cttttcttcg tgaaaatact ataagtatgc
    16381 taaaatagga atagcacatg gagagaggat tcttatgatc aatcacatta cagataatca
    16441 atttaaacta gtatcaaaat atcaaccatc aggagatcaa ccccaagcta tcgagcagtt
    16501 ggtggataac attgaggggg gagaaaaagc tcagattctg atgggggcga ctggaacagg
    16561 gaagacctat actatgagtc aggtcatttc taaagtcaat aaaccaactc tggttattgc
    16621 ccacaataaa actctggctg gtcagctcta tggggagttt aaggaatttt tccctgaaaa
    16681 tgcagttgag tatttcgtat cctactatga ttattaccag ccagaggcct atgtcccttc
    16741 tagcgatacc tatattgaga aggatagttc tgtcaatgac gagattgaca agcttcgcca
    16801 ctcagctacc tcagcccttt tggagcgtaa tgatgttatt gtcgtggcct cagtctcttg
    16861 tatctatggt ttgggttcgc ccaaggaata cgctgatagt gtcgttagtc tccgtcctgg
    16921 tctagagatt tctcgtgata aactcttgaa tgacttggtc gatattcagt ttgaacgcaa
    16981 tgatattgat ttccaacgcg gaagatttcg cgttcgtggg gatgtggtag agattttccc
    17041 agcttcccga gatgaacatg cctttcgagt agaatttttt ggagacgaaa ttgaccgtat
    17101 tcgtgaagtt gaggctctga caggtcaggt gttgggagaa gtggatcatt tagcgatttt
    17161 cccagcgaca cactttgtga ccaatgacga ccacatggaa gttgccattg caaagattca
    17221 ggccgagttg gaagaacaat tagctgtctt tgaaaaggaa ggtaaactgc ttgaagccca
    17281 gcgtttgaaa cagcggacag agtatgatat cgaaatgttg cgtgagatgg gctataccaa
    17341 tggggttgaa aattattctc gccacatgga tggacggagc gaaggagagc ctccttatac
    17401 gcttctcgac ttcttcccag atgatttctt gattatgatt gacgagagtc atatgaccat
    17461 agggcaaatc aagggcatgt acaatggaga ccgttcgcgt aaagaaatgc tggttaatta
    17521 tggtttccgt ttgccgtctg ctttggacaa tcgtcctctc cgtcgggagg agtttgagag
    17581 tcacgttcat cagattgttt acgtttcagc gacacctggt gactatgaaa atgaacagac
    17641 cgagacagtg attgagcaaa tcattcgtcc aacgggactc ttggatccag aggtggaagt
    17701 ccgtccgact atgggacaga ttgatgacct cttgggtgaa atcaatgccc gcgttgaaaa
    17761 aaatgagcgt acctttatca caactttgac caagaaaatg gcagaggact tgaccgacta
    17821 cttcaaggaa atgggtatca aggttaagta catgcactcg gatatcaaga ccttggaacg
    17881 gacggagatt atccgtgacc tgcgcttggg tgtctttgat gtcttggtcg gaattaacct
    17941 gctccgtgaa ggaattgacg ttcctgaagt gagcctcgta gctattctcg atgctgacaa
    18001 ggaaggtttc cttcgcaacg aacgtggact catccagact attggacgtg ctgctcgtaa
    18061 cagtgaaggc catgtcatca tgtatgcaga cacggttacc cagtctatgc aacgtgctat
    18121 cgatgaaact gcccgccgtc ggaaaattca gatggcctat aatgaagagc atggtatcgt
    18181 accacagaca atcaagaaag aaatccgtga cctgattgct gtgaccaagg cagttgctaa
    18241 ggaagaggac aaggaagtcg acatcaatag cctcaacaaa caagagcgca aagaactcgt
    18301 caagaaacta gaaaaacaaa tgcaagaagc cgtcgaagta cttgactttg aactggcggc
    18361 tcagatccgt gatatgatgt tggaagtcaa ggccttggat taggggaata gtatgattta
    18421 tttaagaaag ttaaagagag aagatttgat gtctttatgg gaaatggctt attcacaact
    18481 taatccagtt tggaaacagt atgatgctcc ctattatgat gattatcagt atttttcaaa
    18541 ttttaaagaa ttcgaactac aaaaatcaga atccatttta agcaactcaa atcgccttgg
    18601 tatttttgtt gatgataaac tagttgggac tgtttcgcgt tattgggtat gtaaacaaac
    18661 aagatggatg gaattgggaa ttggtattta tgataaaaaa ttctggaaca ctggtattgg
    18721 gaaagttgct atgttgcagt ggatagatag gacgtttcag gattacttgg agttggagca
    18781 tctgggtttg acaacttggt cagggaatct tggtatgatg aaacttgctg aaaaattaag
    18841 aatgaaaaaa gaagctcata ttccaaaagt tcgttattat caaggtaaat attttgatag
    18901 tattaaatat ggtattttga gagaagactg ggagaaaaca aatgacggtt attatcaaat
    18961 caatggaaac tcctgaagag atagaaggta agccccttgt tcactggcaa acgtggagag
    19021 aggcttatga tggccttttg cctgcagaat ttcaggagac aatgacatta gaaagatgtc
    19081 gattctttag tcaaaagtat ccagaaaata cattgattgc gatggatggt atgaaggtag
    19141 ttggttttat cagttatggc aactttcgtg atgagactat tcaagctggc gaaattattg
    19201 ctttatatgt tttaaaagac tattatggaa aaggtatcgc acaaaagtta ataaaagcag
    19261 ctttgattgc tcttaatcat ttttctgaaa ttttcttatg ggtattgaaa gataataagc
    19321 gcgcaattgc tttctatcaa aaaatgggct ttacttttga tgaacaagaa aagatacttg
    19381 aacttggaaa gcccataaag gaaaaacgga tggtattcta ttctaaataa ttttaaaaag
    19441 tagaagctaa tggtactggt atcaagtcta aaaatttaat aaattagaaa gtgagtaaat
    19501 ttatgtctcg agcacaatta acgattttaa caaatatttg tctgattgaa gatctcgaag
    19561 ctcagcgcgt ggtgatgcag tatcgcgctc ctgaaactaa tcgctggtct ggttatgcct
    19621 ttccaggagg ccatgtagaa aatggcgaat ctttcgcaga gtctgtcatt cgtgaaatct
    19681 atgaagaaac agggttgact atccaaaatc ctcaacttgt cggcattaaa aattggccac
    19741 tagatacagg tgggcgctat attgtcgttt gttataaggc aactgagttc tctggtaccc
    19801 ttcgctcttc agatgaagga gaagtttctt gggtgcaaaa agaccagatt ccaaacttgg
    19861 atctggccta tgatatgcta cctttgatgg agatgatgga agcatcggac aaatctgaat
    19921 ttttctaccc tcgccgtaca gaagacgatt gggaaaagaa aattttctaa tcctttacta
    19981 aataacctag ctgatccaag gcctcctcga tatagtggag gtcttgttgt gtttcggctt
    20041 cgactaggtg gtaatggaca ccatctgtca attcagataa aggtttaaaa tcagaatgct
    20101 cgacttgttc tagaaaatgt tgaacgtctc ggcggcaaga cagtttaagc aaggtttcaa
    20161 tttctccata aacgggatgg tcaatcaaag tattctggac atgcccacca ttatcgacaa
    20221 tagcaaggag ttcctgaccg atttcttcaa cttcatgttt cactttgaaa agtttgtgaa
    20281 cataaggatt ggtatcaatt tgcttataga tgtagccacg attggtggat aggataggag
    20341 cgccatcggc tctcaaaatt gcaatgtcct gcacaatgac ctgacgtgtg acatgaaaat
    20401 gttccgccaa actttggcca ttaagggctt taggagcttc tttcaagagt tggagcaggg
    20461 cttgtttgcg atcttttgtc atagcttttc cttttaacgg cgttttcgaa gcactttata
    20521 gacagctagt gctaatgtat agtctaccat actatggata attgtgccaa atccaactag
    20581 tacaaataga acatagaaca tgttttctac attggtaccc gaagttgcgt aaaaaaggac
    20641 acaggctaat acttcagcaa gggcatgaac aacagccaaa acaaaattga aaacccagga
    20701 agattttggt ttatctaggg tatcggggaa tttttgtagg taaagagatc ctaaagcacc
    20761 aaaagatata tgggaaaaag cccgaaaaac tataaccatg ggatagccag ccatcaaaaa
    20821 tccaaaacta gaggctagga tgacaaaaac tgccatcaag ggcgacaaga acatggctat
    20881 aaaaatagcg atgtggctcc ccaaagtata ggaagcaggt ggaatgacaa tcttgaaagg
    20941 cataacaatt ggaatcaaaa tcgcaatagc cgttaaaagg gctgtcattg tcataaattg
    21001 tgtctttttc cgtgtattca caagaatctc ctttttaact gcatatacac tagtatggta
    21061 caataaacca gacaataaag caagaattta cttgggttta tagatcattt tttagttaaa
    21121 agttatagta gatggaaact agaatagtcc acctctactt ctaaaacatt gttagcgatt
    21181 tgactgtcct gatcgatttg tcctgttctt atttcgtttt actatagtaa agatttcatt
    21241 aaaaagaaac tgtatagagc aaaatctcca ccttcaggtt tgaaagcgga gattgttttt
    21301 attttttcaa ggtttgtagt cgtggaacaa tggctagggt tagaattgca gaaatgacca
    21361 attcagcaat tgaatttgtt gagataacgg ttgccagaag aagttggata tttccattat
    21421 aaacatttcc aaataggaag aagattcctc caaggacaaa gatagtattt gtcaaggaac
    21481 caagggctcc agctaaaatc agaccagtct tgtttttcat cagtttatag actaagtaag
    21541 gagttaaacc aatcaaaata cgtgggacga tggcaatgat agctgagtag atgtttccgt
    21601 ttggtacgaa gggagagaag aggtagcttg tcggtagaat cgtaatcgtg ttaaccgtca
    21661 agctaagtaa tcccatcaaa aatccaagtg taaccccaac tcgtggacca taaataatgc
    21721 tggcaataat gacaggaata tgaacaatgg tcggtttgat tggaaatgga aaaaggttaa
    21781 agataagtga gctcagaaag tgtatcacga gcatggtagc aaaaaagata gcaatgggtg
    21841 caatattaga gcgttttttc atcgatagtt tcctttattc tttctaaaat aattgtgagg
    21901 tcagctaaag ctcctcgtcc gtggtctcca caagctagta gggattcctt aggagcaatc
    21961 agctgatagc cgtaggtttc taatgttttc agattattct gagttactgg atggtcatac
    22021 atttttgtat tcatagcagg agctattagt ttgggaatat gacttggtag ggctagagct
    22081 gtactggtta ccatgttgtc cgcaaatccg tgagctagtt ttgcaatagt gttagcagtt
    22141 gcaggtacca cgataaataa atctgctttt tttccaagtt cgatatgatt gacctgatca
    22201 ggatagggtt ccttcatgac atccaagtgg acaggattct gtgagagtac ctgtagtgtc
    22261 aaaggttgga taaactctgt agcagcctga gtcattaaga cagtgacttg atggccttgt
    22321 ttttttagag aactgactaa atctgccgac ttataagagg cgattgaacc cgttacagcc
    22381 aagagaatgt ttgccatagt tttcctttct aagaatgata ggcttgaatt ttttcaagga
    22441 ggagttctgc aatttcttct ttagtctgga ctgtttgaag ctgatttttc tcaacaaata
    22501 tagctcggtg ctgatctgct gaaatttgag tcaggtcatt cgcgatgatt aaatctgctt
    22561 gattcttgat aagacttttt cgtgcaatgt caaccagatg atcttcggta acatcaacca
    22621 gcagtttgaa accaatcaga tgaatagtgg gattccattc cttgactagg gatatgattt
    22681 tgggtgtctt tttaaggaac aaaacctgaa cctcatcagt tgaagaaatc ttggcctgat
    22741 gattctgctt gcttaaaaat tcttttagat tggagctagc ctgaacttcc tcaagccctg
    22801 tcatataaac aggagtgtag tcagaaacag ccattgagtg gatcaagacc tgataatcct
    22861 gaacacgttc ttgcatttct attagaaggt ccttggtatt ggtaatttct cgaatactta
    22921 ggttaggatg aggctctggc ttcagagctc gttttgtcgt aattaaacaa acttcatgcc
    22981 ctgcagaaag caaagtctct gtgataattt tccccaagtg acctgtagaa tggttagtga
    23041 tagagcggac gctatcgata gcttcactgg taccgcccga tgtaactaaa attttcatag
    23101 cactattgta cacaaaaata agcggtaagt aaaatgaaag tgataaattt ttggtaaaaa
    23161 cgaagattta ctatagtttc aaactataaa gccatataaa atttaagaaa ggactctaaa
    23221 agccttaaaa acagagatat ttacgaacgt ttagagagtt ttaggatgtt aaaaatcttg
    23281 ttttgtgata taatgaatta tcatataaga ggttagagga attttgaatg aaaacagata
    23341 ttgaaatcgc acagagtatt gagttgaagc caattgttga tgttgtagag aaacttggta
    23401 tttcttatga cgatttggag ttgtacggaa agtacaaggc taaactcagc tttgataaaa
    23461 ttcgtgcagt tgagagcaat ccagtcggta aattgatctt ggttactgcc atcaacccaa
    23521 cacctgcagg tgaaggaaag tcgacgctta ccattggtct tgcggatgcc ttgaacaaga
    23581 ttggcaagaa aaccatgatt gctatccgcg aaccgtctct tggtccagtc atggggatca
    23641 agggtggtgc tgctggtggt gggtatgcac aagttctgcc aatggaagac atcaacctcc
    23701 actttactgg agatatgcat gctattacaa ctgccaacaa tgccctttct gccttgattg
    23761 acaaccactt gcaccaaggg aatgagctgg aaattgatca acgtcgtatc ctctggaaac
    23821 gcgttgtgga cttgaacgac cgtgcgctcc gccatgtgac tgttggtctt ggtggtcctc
    23881 taaacggtat tccacgtgag gatggttttg atattacagt tgcttcagaa atcatggcaa
    23941 ttctttgctt ggcaacggac atcgaggact tgaaacgtcg tttggcgaat atcgttattg
    24001 gttatcgcta tgaccgtacg cctgtttctg taggtgattt gcaggttgag ggtgccttgg
    24061 ctttgatttt gaaggatgct attaagccaa acttggttca gacaatttac ggtacacctg
    24121 cctttgtaca cggtggtcca tttgccaata tcgctcatgg ctgtaactct gttttggcga
    24181 cgacaacagc ccttcacttg gctgattaca ctgttactga agctggtttt ggtgcggacc
    24241 ttggtgctga gaaattcctt gatatcaaga caccaaactt gccaacatct ccagatgcag
    24301 ttgtcattgt cgcaaccctt cgtgccctta agatgaatgg tggtgtggct aaagacgctc
    24361 tgactgaaga aaatgtagag gcagttcgtg caggttttgc taacttgaaa cgccacgttg
    24421 aaaatatccg taagttcggt attccagcag ttgtagctat taacgaattt gtatctgata
    24481 cagaagctga aattgcagtc ttaaaagaac tctgtgcctc aatcgatgta ccagttgaat
    24541 tggctagtgt ctgggctgat ggagcagaag gtggagtagc acttgccgaa acagttgtta
    24601 agacaattgc tgaaaatcca gctaactata aacgtttgta cgataatgcc ctttctgtcc
    24661 aagaaaagat tgaaaaaatt gtcactgaaa tctatcgtgg tagcaaagtg aactttgaga
    24721 agaaagctca aacacaaatt gctcaaatcg ttcaaaacgg ttgggacaaa ttgccaatct
    24781 gtatggctaa aactcaatac agtttctcag acaatccaaa tgcgcttgga gcaccagaaa
    24841 actttgaaat taccattcgt gaattggtac caaaattagg tgcaggcttc atcgttgcct
    24901 taactggtga tgttatgacc atgccaggtc ttccaaaacg tccagcagct ctcaacatgg
    24961 atgttgaaag cgatggaact gtactaggct tgttctagtg gattgaaatt gactttaagt
    25021 gagtttggaa ataatatcca agctcatttt ttctcagact gcaagcagtt catcaataag
    25081 atttatactc ttcgaaaatc tcttcaaact acgtcagctt caccttgccg taggtatatg
    25141 atactgactc tgtcagttct atccacaacc tcaaaacagt gttttgagca acctgcggct
    25201 agcttcctag tttgctcttt gattttcatt gagtataagt agatagaaaa gttatatact
    25261 atctattgaa aatattataa atcagataca aagacaggtg aaaccttctg tgttatacta
    25321 gagatatgtt agatttgaaa gaatacggta tcgtcatgtg gccggaggag aaagtcattt
    25381 ctttccgtga gaaacttctc gcttggtatg atgaaaacaa aagagatttg ccttggagga
    25441 gaagtaaaaa tccttatcac atctgggtat ctgaaatcat gcttcagcag accagggtgg
    25501 atacagttat cccttactac gaaagattcc tggactggtt tccaactgtc gaaagtctgg
    25561 caactgcgcc tgaggagagt ttactgaaag cttgggaggg cttgggctat tattctcgag
    25621 ttcgcaatat gcaggctgca gcccagcaga ttatgactga ctttggtggc caatttccaa
    25681 atacctatga aggaatttcc agcttgaaag ggattggacc ttacacagca ggagccattt
    25741 ccagtattgc ttttaacttg cctgagccag ctgtagatgg taatgtcatg cgggtcttgg
    25801 cgcgtctgtt tgaagtcaac cacgatattg ggattccaag taatcgaaaa atttttcagg
    25861 caatgatgga gatcttgatt aatccggatc gtccgggtga ttttaatcaa gccttgatgg
    25921 acttagggtc tgatattgag tctcctgtaa atcccagacc tgaagaaagc ccagtcaagg
    25981 actttagtgc ggcatatcag aatggaacca tggaccgtta tccaattaaa tctcctaaga
    26041 aaaagccggt tcctatttat cttaaagcat tagttgtgaa aaattctcaa ggacaatttt
    26101 tacttgaaaa aaatgaaagc gaaaagctct tggcaggttt ttggcatttc ccccttatag
    26161 aagttgataa cttttcgcaa gaagagcagt ttgacctctt tcatcaggtt gcggaagaaa
    26221 gtgtgaactt tggccccagt ccagaagaga gtttccagca ggactatgac ctagatgttg
    26281 attggcttga tgtttgtttt gatacagtcc agcatgtttt tagtcatcga aaatggcatg
    26341 tacagattgt agcaggtcag gtgagtgact tccatgattt ttcagatagg gaagttcgtt
    26401 ggctttcacc agaagaattc aagaattacc cacttgccaa accccaacaa aaaatctggc
    26461 aggcttatgc acaagccaac ttagacagta gccaagacta gctattgtgt cttctgacta
    26521 ttttttggta taatagtaga gaaaaaggtg aacatatgaa aaaaatacta attgtagatg
    26581 atgagaaacc aatctcggat attatcaagt ttaatatgac caaggaaggt tacgaagttg
    26641 taactgcttt taatggtcgt gaagcgctag agcaatttga agcagagcaa ccagatatta
    26701 ttattctgga tttgatgctt ccagaaattg atggtttaga agttgctaag accattcgta
    26761 agacaagcag tgtgcccatt cttatgcttt cagccaaaga tagtgaattt gataaggtta
    26821 tcggtttgga acttggggca gatgactatg taacgaaacc cttctccaat cgtgagttgc
    26881 aggcgcgtgt taaagctctt ctgcgtcgtt ctcaacctat gccagtagat ggtcaggaag
    26941 cagatagtaa acctcaacct atccaaattg gggatttaga aattgttcca gacgcctacg
    27001 tggctaaaaa atatggcgaa gaactagact taacccatcg tgaatttgag cttttgtatc
    27061 atttagcatc gcatacaggt caagtcatca cgcgcgaaca cttgcttgag actgtctggg
    27121 gttatgacta ttttggtgat gtccgtacag ttgatgtgac tgtacgacgt ctgcgtgaga
    27181 agattgaaga tacgcccagc cgaccagagt atatcttgac gcgccgtggt gtagggtatt
    27241 acatgagaaa taatgcttga tttactgaaa caaaccattt ttaccagaga ttttatcttt
    27301 atcctgattt tgttaggttt catccttgtt gtgaccctct tattactgga aaatagacgt
    27361 gataatattc agttgaagca aatcaatcaa aaggttaaag atttgattgc aggagattat
    27421 tccaaggttc ttgatatgca aggtgggtct gaaatcacca atattaccaa taatttgaat
    27481 gacttgtcgg aggttattcg tctcactcag gaaaatctag aacaagagag taagaggcta
    27541 aatagtattc tgttttatat gacagatggg gttcttgcga ccaaccgtcg gggtcagatt
    27601 atcatgatta acgatacagc caagaagcaa ctggggttgg ttaaggaaga tgttctgaat
    27661 agaagcattt tggaattgct caagatagaa gaaaactatg aattgcgtga tttgattacc
    27721 caaagtccag aattgttgct agattcccaa gatatcaatg gcgaatattt gaaccttcga
    27781 gttcgctttg ccttgatacg tcgagagtct ggctttattt caggtttggt ggctgttttg
    27841 catgatacga cggagcagga gaaggaagaa cgcgaacgaa gactctttgt ttccaatgtt
    27901 agccatgagt tacggactcc tctgactagc gtaaaatcct atcttgaagc cttggatgag
    27961 ggggctttgt gtgaaactgt agcaccagac tttatcaagg tttctcttga tgagaccaac
    28021 cgtatgatgc gcatggtgac ggatctcctc catctttcac gtattgataa tgctaccagt
    28081 cacctagatg tggaactgat taacttcact gcttttatta cctttatcct caatcgtttt
    28141 gacaagatga aaggacagga aaaggagaaa aaatatgagt tggtgagaga ttatcccatc
    28201 aattctatct ggatggaaat tgatacagat aagatgacgc aggttgtcga caatatttta
    28261 aataatgcta ttaagtattc gccagatggg ggtaaaatca ctgtcagaat gaagacaact
    28321 gaagaccaga tgattttatc catttctgac cacggtttgg ggattcctaa gcaggattta
    28381 ccacgtatct ttgaccgttt ctatcgtgtg gatcgtgcta gaagtcgtgc acaaggtggt
    28441 acaggtctag gactgtctat cgctaaagaa attatcaaac aacataaggg ctttatttgg
    28501 gccaagagtg aatacggcaa gggttcaacc tttaccattg tgctccctta tgataaggat
    28561 gcagtgaaag aagaagtatg ggaggatgaa gtagaagact agaatgagtg aaataggctt
    28621 taaatacagt attttagcgt cgggttccag tggaaattct ttttatctgg aaacctcaaa
    28681 aaagaagctt ttagtagatg caggcttgtc tggcaagaaa attaccagtc tgctagctga
    28741 aattaaccgt aagccagaag acctggatgc catcttgatt acccatgagc attcagatca
    28801 tatccatgga gtaggcgttt tggctcgcaa gtatggtatg gatctttatg ccaatgaaaa
    28861 gacctggcaa gctatggaaa atagtaaata tcttggcaag gtggattctt cgcaaaagca
    28921 tatttttgaa atgggtaaaa ccaaaacctt tggagatatc gacatcgaga gttttggtgt
    28981 aagccatgat gcagtcgcac cgcagttcta tcgctttatg aaggatgata agagttttgt
    29041 cctcttgaca gatacaggtt atgtcagtga ccgtatggcg ggcattgtcg aaaatgcgga
    29101 tggttatctt atcgaggcca accatgatgt agagattttg cgatcaggtt cttacgcttg
    29161 gcgcctcaaa caacgaatcc tatctgacct tggtcacctt tctaacgagg acggtgctga
    29221 agctatgatt cggacgctag gaaatcgtac taagaagatt taccttgggc atttatctaa
    29281 ggaaaacaat atcaaggaac tggctcatat gaccatggtc aatcagctgg ctcaagctga
    29341 tctgggagtc ggagtagact ttaaggttta tgatacctca ccagataccg caacaccatt
    29401 gacagagata tagaaagaac gctgagaagg tgttcttttt atattgactg gacacctaaa
    29461 aagtaataca atggtgttac cattaaaaaa gggagcacaa aagatgacta ctattacatt
    29521 aaaagtttct gaagctgata aaacatttat gaaagcaatg gctaagtttg aaggagtttc
    29581 cctttcggaa cttattcgca ccaaaactct tgaagcccta gaagatgaat acgatgctcg
    29641 tgtggcagat ttagcctatc aagagtattt agaagacttg gaaaaaggag ttgaacccat
    29701 tacttgggaa gaaatgatgc atgatttagg cttgaaggat gaataatttg tataaattag
    29761 ttccaacaag acgttttatc aagcaattga aaaaattgga ccgttatacg cagaagctaa
    29821 ttacaaacta tttacaaacc aatgttttgg aagatccaag acgacacgga aaggctttgg
    29881 ttggtaatcg cgttggtcaa tggcgctata gaattggtaa ttatcgagtt atcgtacaaa
    29941 ttgtagatga tgaattagtt gttgctactc tagaagttgg tcatcggaga gatatttatt
    30001 aaattaaagc tgagtaataa cagtatagaa agtaaggaga gtaaaaattt gaagaaaaaa
    30061 tggttttttg cagattatta tgacacaaca attattttac ttgctttaat ctctgttatt
    30121 ctggtattac ttggatttgc tgagatgatt gatttggaca atccgcctta tagtattatt
    30181 gatttagtaa tctggggtgt ttttgtaatt gattatagtt ggcgcttttt tacgactaaa
    30241 agaaaatggc gctttattct tgaaaatatt tttgatttat tggctattct ccctttaaat
    30301 gctattttta cagtgtttcg attagggcgt atctttcgtt tagctaaact aacaaaatta
    30361 ctgaaactga ctcgtttact tagaataatt ggacttacag gtaaattaga aagaaaaatt
    30421 agtagattct tacggacaaa tggcctgatt tatatcttgt atgttaatat ctttattgtt
    30481 ctagtaggga gttcgatttt atccgttgtt gaagaaaaat ccttctcaga tagtctttgg
    30541 tgggctcttg tgacagtaac tactgttgga tatggggata ttgttcctgc ttccattttt
    30601 gggaaatggc tagcagtttt actgatgctt gtcggtattg gaacaatagg gatgttaaca
    30661 agtgctttga cgaacttttt tgtaaaggat aatccagatg aacagataaa acttgataaa
    30721 ctcaaagatg aattatcgag ccaaagaata ttactagaga aacaatctaa aaagatagaa
    30781 gaactacata aaatgataca agatttgatt gaaaaaacat aataaaaata aagatgagac
    30841 aaagtttgag ctgaggagaa atcaagtaag ttttgacaca atagaacgca tattatcagg
    30901 tataaaaact tgatactatg cgttttatag agaaataaaa taaaatctga acaaatcaat
    30961 taggaattta aagcatttta taacaacgtt ttagagtgat ggggtgctat ttcaacttca
    31021 acctactata atacagaaaa aaacaactcc ctgatgattc aaggagttgt ctatagttaa
    31081 attagttttt agaagcttct tggaattctg gatttttcca tgcttcgtca ataatagctt
    31141 gcaattcttt agcagatgct tgcatttttt gagtttctgc atcgttcaat ggaatgttta
    31201 ctggacgaac gataccatgt gcaccaacaa cagctggttg accgataaag acattctcaa
    31261 ctccgtatag accttcttgg aatactgaaa gtggaagtac tgcgttttca tcgtcaagga
    31321 ttgctttagt gatacgagca agggctactg cgataccgta gtatgttgca ccttttttgt
    31381 tgatgattgt gtaggctgca tcacgaacac cttcgaacaa ttcaatcaat tcagcttctt
    31441 gaacattttg agtgtcttta aggaattctt caaggtttac accagcgatg ttagcgtgtg
    31501 accaaacagc gaactcagag tcaccgtgtt cacccatgat gtaggcgtgc actgaacgag
    31561 catccacatc caatttttca gcaagtgctt gacggaaacg agctgagtca agtgaagtac
    31621 ctgaaccgat aacgcgttct ttagggaaac cagagaattt ccaagttgag taagtcaaaa
    31681 cgtcaactgg gttagcagca acaaggaaga tacctttgaa accagattca acaacttgag
    31741 ttacgattga tttgttgata gcaaggtttt tacctacaag gtcaagacga gtttcacctg
    31801 gtttttgagg tgcacctgca gtaatcacaa caaggtcagc gtctgcacag tcagagtatt
    31861 gagctgcata gattttttta ggtgaagtga aggcaagggc gtgactaagg tcaagcgcat
    31921 caccaacagc tttttcatgc aattgtggaa tttcgataat tccaagctct tgtgcaattc
    31981 cttggttaac aagtgcaaaa gcgtaagatg aacctacagc accatcaccg acaaggataa
    32041 cttttttgtg ttgtttagtt gaagtcattg ttttaaacat ctccttaatt ttattagggg
    32101 attttcccta gacaacttca ttctatcact tttaaaaaac tttgtcacga atatgcctta
    32161 tagttctcga tgtaaacgtt ttagtggttt agaggctgaa atagatggga atttatggta
    32221 taatgttgtt acttactaat tgtgaaatga ggcatttatt aatgcaggat aaaaatttag
    32281 tgaatgtcaa tctgacaaag gagatgaagg caagttttat cgactacgcc atgagtgtta
    32341 tcgtagcgcg agctcttcct gatgttcgag atggcttaaa acctgttcac cgtcgcattc
    32401 tctacggaat gaatgaattg ggtgtgaccc cagacaaacc ccataaaaaa tctgctcgta
    32461 ttacagggga tgtcatgggt aaatatcacc cacacgggga ttcctctatt tatgaagcca
    32521 tggtccgtat ggctcaatgg tggagctacc gttacatgct tgtagatggt catgggaatt
    32581 ttggttccat ggatggagat agtgctgccg ctcaacgtta taccgaggca cgtatgagca
    32641 agattgctct ggaaatgctt cgtgatatca acaaaaatac agttgatttc gttgataact
    32701 atgatgccaa tgaacgggaa cccttggtct tgccagcgcg ttttccaaac cttttggtta
    32761 atggagcaac tggtatcgcg gttgggatgg caaccaatat tccacctcat aatctgggtg
    32821 aaaccattga tgcagtgaag ttggtcatgg ataatcctga agtgactacc aaggacttga
    32881 tggaagtctt gcctggacca gattttccaa ctggtgctct tgtcatgggg aaatcaggta
    32941 tccataaggc ttatgaaaca ggtaaaggtt cgattgccct acgttctcgt acagagattg
    33001 aaacgactaa gactggtcgt gagcgcatcg ttgtaacaga atttccttac atggtcaata
    33061 aaaccaaggt gcatgagcat attgttcgct tggttcagga aaaacgcatt gagggtatca
    33121 cagcagtacg tgatgagtca aaccgtgaag gtgttcgatt tgttattgaa gtcaagcgcg
    33181 acgcctcagc caatgttatt ctcaataacc tcttcaaaat gacccaaatg caaaccaatt
    33241 ttggtttcaa tatgctcgct atccaaaatg gtataccgaa aattttgtct cttcgtcaga
    33301 ttttggatgc ttatatcgag caccaaaaag aagtggttgt tcgtcgtaca cgttttgata
    33361 aggaaaaagc ggaagcgcgc gctcatatct tagaaggtct cttgattgcg ctagaccata
    33421 tcgacgaagt gattcgtatc atccgtgcta gtgaaacgga tgcggaagct caagctgagt
    33481 tgatgagcaa gtttaagctt tctgaacgtc aaagtcaagc tatccttgat atgcgtcttc
    33541 gtcgtttgac aggtttggaa cgcgataaga ttcaatctga gtatgatgac ctcttggctc
    33601 tgattgcgga tttagcagat attcttgcta agcctgaacg tgtttctcaa attatcaaag
    33661 acgaattgga tgaagttaaa cgtaaatttt ctgataagcg ccgtacagag ttgatgattg
    33721 gacaggtctt gagtctcgag gatgaggact tgattgaaga atcggatgtc ttgattaccc
    33781 tttctaacag aggctacatt aagcgtttgg atcaggacga gttcactgct caaaaacgtg
    33841 ggggtcgtgg tgtccaagga acgggagtga aagatgatga ctttgttcgt gagttagtgt
    33901 caactagcac ccatgatcat ctgctcttct tcacaaacaa gggacgtgtc tatcgtctta
    33961 aaggttatga aattcctgag tatggtcgga ctgccaaagg gctaccagta gtcaatctct
    34021 tgaaattgga tgaagacgaa agtattcaga cggttatcaa tgttgagtct gatcgcagtg
    34081 atgatgctta tctcttcttt acaacccgtc acggtattgt gaagagaacc agtgttaagg
    34141 agtttgccaa tattcgtcaa aatggtctca aagcgctgaa tttaaaggat gaagatgagt
    34201 taatcaatgt cttgttggca gaaggagata tggatattat cattggtacc aagtttggtt
    34261 atgcagttcg ctttaatcaa tcagccgttc gtggtatgag tcgtatcgcc actggtgtga
    34321 aaggtgttaa ccttcgtgaa ggagacacag ttgttggtgc cagcttgatt actgatcaag
    34381 atgaggttct tattatcaca gaaaaaggat atggtaagcg tacagtcgct actgaatacc
    34441 caacaaaagg tcgtggtggt aagggaatgc agacagctaa aattaccgaa aaaaatggct
    34501 tgctggccgg tcttatgact gttcaagggg atgaggattt gatgattatc actgatacag
    34561 gtgtcatgat tcgaaccaat cttgccaata tttcacaaac aggacgtgca actatgggag
    34621 ttaaagtaat gcgcctggat caagatgctc agatagtgac tttcacaacg gttgcggtgg
    34681 cagaaaaaga agaagttggg acagaaaacg aaacagaagg tgaagaataa tgtctcaaaa
    34741 aaataataaa aagaaaaaca agcgaaaaaa tctgctgaca aatatcctag caggatttct
    34801 gatattactg tcactggctt tgatttttaa tactcaaatt cgaaatattt tcatagtctg
    34861 gaataccaat aagtatcaag ttagccaggt atcaaaagaa aaattagaag aaaatcagga
    34921 tacagaaggc aattttgact ttgattctgt caaagctatc tcttcggaag ctgttctaac
    34981 ttctcaatgg gatgctcaaa aattaccagt tattggggga attgcaattc ctgaattgga
    35041 aatgaatttg ccgattttta aaggacttga taatgttaat ctcttctacg gagctggtac
    35101 aatgaaacgc gagcaagtaa tgggagaagg aaattatagt ctagctagtc accatatctt
    35161 tggtgttgat aatgctaata aaatgttatt ttctccttta gataatgcta aaaatggcat
    35221 gaagatttat ctaaccgata aaaataaagt ttatacttat gaaatacgtg aagtcaaacg
    35281 tgtgacaccg gatcgtgttg atgaagttga tgatagagat ggggtcaatg aaatcacatt
    35341 agtaacctgt gaagaccttg ctgctacaga acgtattatt gtcaaaggtg atttgaaaga
    35401 aacaaaagat tattcacaaa catctgatga aattctaaca gctttcaatc aaccatataa
    35461 acaattttat taatacaaat cagtgaaatc atggatttca ctgatttttt aagattttca
    35521 taaaaatata gtaaaatgaa ataagaatag gacgaatcgt tcaggacagt caaatcgatt
    35581 tctaacaatg ttttagaagt agaggtgtac tattctagtt tcaatctact ataaactttt
    35641 atgaaataca gaaaacgctt cctaaaacct aaagtttgtg atataattat caagaaaaaa
    35701 gatttaggag tttattatgg tttcttcaga atttatctca aagattgaat ttgcttgcaa
    35761 taagaaagaa agtctttata gtcaaagcaa atttaagtat gcgattcgtt cgatgttcgc
    35821 aggtgcattt ttaaccttca gtactgctgc aggtgcagtt ggggctgact tgattaataa
    35881 aattgcacca ggtagtggac gcttcctctt tccattcgtt tttgcttggg gcttggccta
    35941 cattgttttt ttgaatgccg agttggtcac ttcaaacatg atgttcttga ctgctggtag
    36001 tttcttaaaa aaaatctctt ggagaaaaac agctgagatt ttactatact gtaccttgtt
    36061 caaccttatc ggagccttga tagcagggtg gggctttgct cattcggcag cctatgcgaa
    36121 tctgacacac gatagtttca tctcaggtgt tgttgagatg aagttaggcc gctcaaatga
    36181 attggtcttg cttgaggcga ttttggcaaa tattttcgta aatattgcga ttctgtcatt
    36241 tattttggtc aaagatggtg gtgccaaact ttggcttgtg ttgtcagcta tttacatgtt
    36301 tgtattctta acaaacgagc acattgcggc gaactttgct tctttcgcga ttgtgaaatt
    36361 cagtgttgct gcggattcaa ttgccaactt cggtgttgga aatatgcttc gccactgggg
    36421 tgtgactttc atcggaaact ttatcggagg aggcctcttg atgggtcttc catatgcctt
    36481 cctcaataaa aacgaagata cttatgtaga ttaagaaaat gagcacgatt gagtcgtgct
    36541 tttttcattt tcaaaataag gtaatagcta tttcttatat caaaatatag aaaactgata
    36601 tttgtaaact ataactcaag gtgctacaat atccttaata aaatgatatg gaggtcacct
    36661 tatgacttgt gattttaaat ttgaaactct acaactacat gctggtcaag ttgtggctcc
    36721 agctactaag tctcgtgcag tgccgattta tcaaacaaca tcttttattt ttgatgacac
    36781 gtaggaaggt gctgatctgt ttgccttgag gaaaccaggg aacatttata ctcgtatcac
    36841 caatcctaca acagctgccc ttgaaggtgg tgttgaagcg ctagcaacag catcaggtat
    36901 gactgcagtg acttatacga ttttggcgct tgcccatgct ggtgaccatg tagtggctgc
    36961 ttcgactatt tacggtggaa ccttcaatct tttgaaagaa ccccttcctc gttatggtat
    37021 cacaacaacc tttgtcgatg ttgataattt ggaggaagta gaagcagcta tcaaagacaa
    37081 taccaagctt gtcttgattg aaaccttggg taactccttg attaatattc cagacctgga
    37141 aaaactggca gagattgctc ataaacatca aatcccactt gtgtcagaca atacttttgc
    37201 aataccttat ttgattaacg tcttctctca tggcgttgac attgccattc actctgcgac
    37261 taagtttatc ggtgggcatg gtacaactat tggaggaata attgtcgata gtggtcgttt
    37321 tgactggacg gcttcaggga aattccctca atttgttgac gagggtccaa gctgccacaa
    37381 tttgagttat acttgtgatg tgggtgcagc agcctttatt atagctgttc gagttcaatt
    37441 gcttcgtgat acaggtgcag ccttgtcacc attcaatgct ttcctcttgc tacaaagact
    37501 tgaaacctct tcacttcgtg tggaacgcca tgtacaaaat gctgagacaa ttgttgattt
    37561 tcttgtcaac catcctaagg tagaaaaggt aaattatcca aaacttgcag atagtcctta
    37621 tcatgccttg gctgagaaat acttgccaaa agatgtcggt tcaatcttta ccttccatgt
    37681 caaaggtggc gaggaagaag cacgcaaggt cattgataat ttagaaatct tttctgacct
    37741 tgcaaacgcg gcagatgcta aatcgcttgt tgtccatcca gcaacaacca ctcacggtca
    37801 attgtcagaa aaagacctag aagcagcagg tgtcacacca aactaaattc gtttgtcaat
    37861 cggtcttgaa aatgtagaag atttgattga agacttgcgc ttggccttgg aaaaaattta
    37921 aagtaaaaga agataaacag tgggcttcga ctcactgttt ttgattttcc ctcaggcatg
    37981 atataatggt taaagaagtc tagaaagagg aacgatatga acgaaatcaa atgtcccaac
    38041 tgtggggaag tctttacagt aaatgagagt cagtatgccg aactcttgtc ccaagtgaga
    38101 acggcagagt ttgataagga actacacgat aggatgaagc aggaactggc cttggctgag
    38161 caaaaggcca tgaatgagca acagactaaa ctggctcaga aggatcaaga aattgcgcaa
    38221 ttacagagtc agatccaaaa ctttgataca gaaaaagaat tggccaagaa agaggttgaa
    38281 cagacaagcc atgaggctct cttggctaag gacaaggaag tacagctctt agaaaatcag
    38341 ttggctacct tgcgtttgga gcatgaaaat caactgcaaa agaccctttc tgacctagaa
    38401 aaagaacggg atcaggttaa aaaccaacta cttttgcagg aaaaggaaaa tgaattatct
    38461 ttggcttctg ttaagcaaaa ctacgaagcc cagctcaagg cagctagtga acaagtcgag
    38521 ttttataagg attttaaggc tcaacaatct acaaaagcga ttggggaaag cctagaacag
    38581 tatgcagaga gtgagtttaa caaggttcgt agtttcgcct ttccaaatgc ttactttgag
    38641 aaggataaca aggtctcttc gcgtgggtct aaaggggact ttatcttccg tgagtgtgat
    38701 gaaaatggag ttgaaatcat ttctatcatg tttgagatga aaaacgaagc agacggaaca
    38761 gagaagaagc acaagaatgc agatttttac aaggaattgg acaaggaccg tcgggagaag
    38821 aactgtgagt atgccgtttt ggtgaccatg cttgaggccg ataatgacta ctttaacaca
    38881 gggattgttg acgtcagcca cgagtatgaa aaaatgtatg ttgttcgtcc tcaattcttt
    38941 atccagttga ttggtctctt acgtaatgcg gcgctaaatt ccctaaaata caagcaggag
    39001 ttggccttgg ttcgcgagca aaatattgac attacgcatt ttgaggaaga cttggatgcc
    39061 tttaagctag cttttgctaa gaactataat tcagcttcga ctaactttgg aaaagctatt
    39121 gatgaaatcg acaaggccat caaacgcatg gaagaggtta agaaattcct gactacatct
    39181 gaaaaccaac tccgtctagc taacaacaaa ttggaagatg tctctgttaa aaaattgacc
    39241 cggaaaaatc caacaatgaa agcgaagttc gaagcactga agggggagta gaaagcaaaa
    39301 atgaacggta ttatcaactt aaaaaaagaa gcaggaatga cctcgcatga tgcggttttt
    39361 aaactgcgta agattttggg aaccaagaaa attggtcatg gtggaacctt ggatccggat
    39421 gtggtgggtg ttttgccgat tgcggttggc aaggcgacac gcatggtcga gtttatgcag
    39481 gacgagggta agatctatga gggggaaatc attctgggct attccacgac gactgaggat
    39541 gctagtgggg aagtggtcgc agaaacccct gttttgtctc ccttggatga aaagcttgtt
    39601 gatgaagcga ttgctagctt gactgggcct attactcaga ttccccctat gtattcggca
    39661 gttaaggtta atggtcgcaa gctctatgag tatgcgcgtg ctggtcagga agtggagcgt
    39721 ccagaacgtc aggtgaccat ttatcaattt gagcgaacaa gtccgatttc ttatgatggc
    39781 caacttgccc gattcacttt tcgtgtaaaa tgcagtaaag ggacttacat ccgtactttg
    39841 tcagttgatt tgggtgaaaa gcttggttat gcggctcata tgtcccattt gactcgtact
    39901 agtgctgctg gcttacaatt agaagacgct cttaccttgg aggaaattgc tgaaaaagta
    39961 gaggctgggc aattagattt tctccatcct ttagagattg ggacaggtga ccttgtcaaa
    40021 gttttcctaa ctccagaaga ggctacagaa gttcgctttg gtcgttttat tgagctagac
    40081 caaacggaca aagaactggc tgcctttgaa gatgataaat tgttagccat tctagaaaaa
    40141 cggggcaatc tctataagcc aaggaaggtt tttagctaga tcgtttagga ataaaaatcg
    40201 ggtgatagat aacaattgct tgataaaccc ccatactaat agtagaatgg ttttgggaat
    40261 tataatattc caattgttgc gagttgtaga tactcaaata atctatatag aaatttagag
    40321 gtgtgaaatg aagcaactta aaattctttc agataaatat ttagagtcca tgacaggttc
    40381 tggtgggaac ttaggtctag gatttggtgt gataattcca tgatgtgaaa tgagtttcga
    40441 gaaagggtgg agcaacttct tcaacaaaaa gaaataaatg aaaatagtga gttgagtcac
    40501 ctgtttcgtc ttgctataca aaatttagac agaaatgaaa aataccaatc ggtcatggcc
    40561 aatttgagtc aagggttgtc actttacctc atgacgcatc attaccaggc acctaagtct
    40621 gtcattgatt ttggtttatg gattgccaaa gctcctagcc aggaaagagg gagactggct
    40681 ttcttgcaga tgcttgctca aaccctacag ggctttcgtt aaaactgtcg aacatcagag
    40741 ggaagactct ggtgtttttt gctgatgaga ctataaattt tgtaaaaaat gtgatagaat
    40801 agacgacgga taaaataacg gaggatagca tgcaaaatag accaatcatt attggagtga
    40861 caggtggttc tggtggtggt aaaaccagtg tttcaagagc cattttatcg cattttcctg
    40921 atgaaaagat ttccatgatt gagcatgatt catactacaa ggatcagtct catttgacct
    40981 ttgaagagcg tgtcaaaacc aactatgacc atccttttgc ctttgataca gacttgatga
    41041 tcgagcagat taaggaattg ttggcagggc gtccggtgga catcccgacc tacgactata
    41101 cagagcatac acggagtagc aagacctatc gtcaggagcc tcaagatgtc tttatcgttg
    41161 agggcatttt ggtcttggag gacaagcgtc tgcgcgattt gatggatatc aagatttttg
    41221 tggatacgga tgacgatgtg cgtattattc gtcgtatcaa gcgtgatatg gaggaacgtg
    41281 gccgtagcct tgatagcgtt attaaccagt acttaggtgt ggtcaaacca atgtaccacc
    41341 agtttatcga gtcaactaag cgttatgctg atatcgtcat tcctgaaggg gttagcaata
    41401 ccgtggctat cgacctgttg acgaccaaga ttgcaaagat tttggaagaa gctcgaaaca
    41461 gcaaataatc acatgtggag gccttgcctc ctttttctat ttttccctca taatggtaca
    41521 taaatggaga tttttaggca tatttttggt ataataatac ccataaaaga gcaagtaaat
    41581 gaatagtagg tggagatgga aaagtattta tcggtaacaa ctttgaccaa atatctgaaa
    41641 atgaaattcg ataaagaccc atacttggaa cgggtctatt taactggtca agtttccaac
    41701 tttcgtaaac gacctactca ccaatatttc tccctaaagg atgaccatgc agttattcaa
    41761 gcgaccatct ggtctgggat ttatcagaaa ttagggtttg acctggaaga aggaatgaag
    41821 atcaatgtga ttgggcgtgt acaggtctat gaaccaagtg gtagctactc catcatcatt
    41881 gaaaaagctg agcctgatgg ggttggggcg cttgcgattc agtttgaaca acttaagaaa
    41941 aaattgacag aagaaggcct gtttcaagaa cgcttcaagc aagctctacc ccaattttct
    42001 aagagaattg gggtagtaac cagccgtagt ggagccgtta ttcgagatat tatcacgacc
    42061 gtcagcaggc gattcccagg tgttgacatc cttctttatc ctaccaaggt tcaaggtgaa
    42121 ggggctgcgg aggaaattgc tagaaatatt gcgcgtgcta atcaacggga cgatttggat
    42181 ttgctcatta ttggtcgtgg aggtggttct attgaggatc tctgggcctt taacgaagaa
    42241 attgtggtac gagctatttt tgaatctcgt ttgccagtta tctctagtgt ggggcatgag
    42301 acggatgtga ccttggcaga ttttgtggca gatcgacgcg ctgcaacgcc aacagcggcg
    42361 gctgaactgg caacacctgt gaccaagttg gatgtattag ctcatttgca aaatcaggaa
    42421 aaacggatgg caacggcagt ccgaaatgtt ctatctaaga aacaagaggc tttgaaaaaa
    42481 tgcagtcagt ctgttatctt tagacaacct gagcgcttgt atgacggtta tttgcaacgc
    42541 ttggaccaac tgcaactgcg tttgaaacaa agtttgcgaa ctcggatttc tgataacaaa
    42601 caattagttc aagcaagaac tcatcaatta gtacaattat cacctgttac caaaatccaa
    42661 cgctatcaag accgtttagg acagttggac aagctcttag gtagccaaat ggcgttagtt
    42721 tatgacgcca aggttgctga ggccaagcga ctttcggaag ctttgctcat gttggatact
    42781 agccgaatcg tggcgcgtgg ttatgctatt gtcaaaaaag aagagtccgt tgtagattcg
    42841 gttgagagtt tgaagaaaaa agaccaagta acgcttttga tgcgagatgg tcaagtagaa
    42901 ttagaggtta aagatgtcaa aacaaaagaa atttgaggaa aatctagcag aactggaaac
    42961 cattgtccaa agtttggaaa atggtgaaat tgctctggaa gatgcgatta ctgcctttca
    43021 aaagggcatg gtcttgtcaa aagagctcca agctacgctg gacaaggctg aaaagacctt
    43081 ggtcaaggtc atgcaagaag acggaacaga aagtgatttt gaatgaaaaa gcaagaaaaa
    43141 ttagctcttg tcgagtcggc tttggaagat ttttatggag accagcagtt tgcctctagt
    43201 ttacgggagt ctgttctcta ttctattcat gctggtggca agcgtattcg gccttttctc
    43261 ttgttagaag ttctggaatc cttgcaggtt accatcaaac ctgctcacgc gcaggtagct
    43321 actgccttgg agatgattca tacagggagc ttgattcacg atgaccttcc tgctatggat
    43381 gatgacgatt atcgaagagg gcggttaacc aatcacaaga aattcggtga agctatggcc
    43441 attttggctg gagatgcctt attcttagac ccatatgcct tgattgcgca ggcagatttg
    43501 ccaagtcaga tcaaggtgga cttgattgcc aacttatccc ttgcttcagg tagtctgggt
    43561 atggtggcag ggcaagtttt ggatatggag ggcgaacacc agcacttgtc tctggaagaa
    43621 cttcagacta ttcatgccaa taagactggg aagttactag cctatccctt ccaagcggca
    43681 gctattatag ctgaattgtc acctgaaatg caggtgaagc tgaaaactgt gggtgaattg
    43741 attggacttg cttttcaagt cagagatgat gtactggatg tgacagctag ttttgaggaa
    43801 atcggcaaga cacctcaaaa ggatctgcag gcagaaaaat caacctatcc tgccttgttg
    43861 ggcttggaag agtccattgc cttttgtaac caaaccctgg atcaagctaa tgaaaaatta
    43921 gaagaaattg cccagcagct tccctttgaa acagaatcga ttgtaagtgt agtagaaagt
    43981 ttgagaatca atggctaagg aaagagtgga tgtactagct tataaacagg ggttgtttga
    44041 aacgagagag caggccaagc gaggtgtgat ggctggtcta gtcgtagcag tccttaatgg
    44101 agaacggttt gacaagccag gagagaaaat tccagatgac accgaattaa aactcaaggg
    44161 ggagaaactc aagtatgtca gccgtggtgg tttgaaactg gaaaaggcct tgcaggtctt
    44221 tgatttgtcg gtggatggcg cgactacgat tgatatcggg gcctctactg gaggttttac
    44281 cgatgtcatg ctacagaata gtgccaagtt ggtctttgca gtcgatgttg gtaccaatca
    44341 gttggcttgg aaattacgcc aagacccacg agttgtcagc atggagcagt tcaattttcg
    44401 ctatgctgaa aagactgatt tcgagcagga gccgagcttt gccagtattg atgtgagttt
    44461 catttccctt agtctgattt tgccagcctt gcacagtgtc ttggctgatc aaggtcaggt
    44521 ggtagcactt gtcaaacctc agtttgaggc aggacgtgag cagattggga aaaatggaat
    44581 tattcgagat gctaagattc atcagaatgt ccttgaatct gtaacagcta tggcagtaga
    44641 ggcaggtttt tcagtccttg gcttggactt ttctcccatc caaggtggac atggaaatat
    44701 tgaattttta gcgtatttga aaaaagaaaa gtcagcaagc aatcagattc ttgctgagat
    44761 taaagaagca gtagagaggg cgcatagtca atttaaaaat gaataaaaaa gaaagacttg
    44821 aaaaaattag aagattggtg acagattatc aaatcggcac gcaagaagaa attgtagaac
    44881 atttgaaaga agcaggtatc actgccactc aggcgacggt atcccgagat atcaaagagt
    44941 taggtattgt caaaattcct ttgagagaca acacctatgt ctacgaattg ccaaaatcaa
    45001 tcgtaaaaag tctgcaactg gctgaagaca atatcgaatc ggctgaattg atggataaga
    45061 tgatcaatct ccaagttatt ccaggaaata cggcttttgt aaaagctcag ttaatcgaga
    45121 cttttgcaga caagattttt agctgtttga ctgatgatag ctcgatttta gtcattgcca
    45181 gaagtggaag tctagcagag gaaatctttg aacaagtaaa aaattggtag gtctatatgt
    45241 tacttgaaat ttcgataaaa aactttgcca ttattgaggc tatttccctc aattttgaaa
    45301 aggggatgac tgtcctgact ggtgaaacgg gtgcagggaa gtcgattatc attgatgcca
    45361 tgaatatgat gttgggagct cgtgcgacga cagatgttat tcgtcatggt gcaccaaagg
    45421 cagagattga ggggcttttc tcagttgaga atagtcgtct tttacaggaa atttttgatg
    45481 agcaaggttt agaattaggt gatgaaatta tcatccgtcg ggaaatcttg caaaatggtc
    45541 gtagtatcag ccgtgtaaat ggtcagatgg ttaatctgtc tgttttgcga actattgggc
    45601 aacatcttgt agatattcat ggtcagcatg accatgagga gttaatgcgt ccccaactgc
    45661 atatccagat gttggatgaa tttggtgatg ccgctttttg ggacttgaaa gaaacctatc
    45721 aaacgagttt tgatgcctat cggaaaatgc gcaagcaggt tctggaagtc aagaaaaacc
    45781 aacaggaaca caaggcacgt atcgaaatgt tggaatttca aatggcagag attgaggcag
    45841 caaacttgca ggctggagaa gacttggatc tcaatcaaga gcgagataaa ctcctcaacc
    45901 acaaaaatat tgcggataca ctgaccaatg cctacagtat gttggacaat gaagattttt
    45961 caagtctggc caatgttcgt tcagccatga atgacatgga aagtgtcgaa gagtatgacc
    46021 ctgaataccg tgaaatttca agctctctgt ctgagaccta ctatgtttta gaagacatta
    46081 gcaaacgttt ggaagctatc attgaggacc ttgattttga tggcaatcgc ctcatgcagg
    46141 ttgagaatcg tttggacctc cttcatacta ttactcgtaa gtatggtggg actgttgatg
    46201 atgttttgct ttattttgcc aagattacgg aagaatacaa tctcttgaca ggcaataatc
    46261 tttcgtctga ggacatggaa gcagagctta agaagttgga agtcaatctt gtcaatttgg
    46321 caggtcaact tgcttctgct cgtcataatt tggctcagca actcgaagct gagattaaac
    46381 aagaactgca agatctttat atggaaaaag cccagtttca ggttcgtttt agtaagggaa
    46441 aattcagtcg tgagggaaat aaaatggttg agttttatat ttcaaccaac cctggagaag
    46501 actttaaacc cttggttaag gttgcttctg gaggggaatt atctcgtctc atgttagcca
    46561 ttaagtctgc cttttcacgt aaagaaggca agactagcat tgtctttgat gaggtggata
    46621 cgggagtttc aggtcgtgtt gctcaagcta ttgctcagaa aattcataaa attggtcagc
    46681 atggtcaggt tttggctatc tcccatttgc cacaagtaat tgcgattgca gattatcaat
    46741 tctttattga gaagattagt aatgaccatt caacggtttc gactgttcgt ctcttgacgg
    46801 tcgaagagcg agtggaggaa gttgccaaga tgttggcagg tgatgatgtg acagaagcag
    46861 ccctgacgca agcaagagaa ttgttgagaa acagggagaa ataagatgac agattattat
    46921 gtaattggag atgttcacgg aaaagctggg atgctggaag accttctcaa aacctgggat
    46981 ggtcagcccc agttgctctt tctaggtgat ttgattgaca gaggtgagga tagtcaccgt
    47041 gttcttgaaa tggtcaagga cttggtggac aatcaagggg ctatctgttt gtccggaaac
    47101 cacgagtata tgtttttgac ttggctagat gacccagaag aaagttatga ccattatagt
    47161 cgcaatggtg gagatacaac cattaactct atcctaggtc gtcccttgga tgcaccagtt
    47221 gatggagtag aagatgccaa gcgggttgcc gctgaagcgg cagacttggt cgaattcatt
    47281 cgtcaaatgc catttgtagt agagacagac aagtatatct ttgttcacgc aggtattgat
    47341 ttgaccttgg acgactggca tgaaacaaca gattataaaa aagtatggct tagaaaacca
    47401 ttccacggag ctgaaaatca tactggaaaa accattgtct tcggtcatac accggtctat
    47461 ggtttattac agcaagaacg cggtacatct gagctttgga ctacagaaga tggcaagatt
    47521 ggaatggatg gaggagctgt ttatggtggt gtccttcacg ggattgtctt tacagaccaa
    47581 ggaatgacag aacaccactt tatcgaaaat gacggctttg tcgctgaaga ttagtactcc
    47641 tagcagggta tggtcttgtc aaaatatcaa aaacaattta taataaatag ataccctgaa
    47701 aggaagagaa tcatgaactt agaagaattg aaaaaacgac aggagaagat ccgtaacttc
    47761 tctattatcg cccatattga ccacggaaaa tcaactctag cagaccgcat tttggaaaaa
    47821 acagagacgg tttcaagtcg tgaaatgcag gcccagcttt tggatagcat ggagctagag
    47881 cgggaacgtg gaattactat taagttgaat gccatcgagt tgaattacac tgcaaaagat
    47941 ggggaaactt atattttcca cttgattgac acaccagggc acgttgactt tacctatgaa
    48001 gtttcacgtt cgctagctgc ctgtgagggt gctattttgg tggtcgatgc ggctcaagga
    48061 attgaggctc aaactcttgc caacgtttat ctggctttgg ataatgattt ggaaatcatg
    48121 cctatcatta ataaaattga cctgccggct gcagatccgg agcgcgtgcg tacagagatt
    48181 gaagatgtga ttggtttgga tgccagtgaa gcagttttgg cttctgccaa ggctggtatt
    48241 gggattgaag aaatcctcga gcaaattgta gaaaaagtac cagcaccaac gggtgatgtg
    48301 acggcgccac ttaaggcctt gattttcgac tctgtttacg atgcttaccg tggggttatc
    48361 ctccaagtgc gtgtcatgga cggagtggtc aaacctggtg ataagattca gctcatgagc
    48421 aatagtaaga cctttgatgt ggccgaagtc ggtattttta caccaaaagc ggttggtcgt
    48481 gatttccttg cgactggtga tgttggttac attgcggcgt ctatcaagac ggttcaggat
    48541 actcgtgtgg gtgataccgt taccttggca accaatcctg cggcagaacc attacatggt
    48601 tataagcaga tgaatcctat ggtctttgcg ggtctctacc caatcgaatc aaacaagtac
    48661 aatgacctgc gtgaagcgct tgaaaaattg caactgaatg atgctagtct tcagtttgaa
    48721 ccagaaacat ctcaggcact tggatttggt ttccgttgtg gatttcttgg acttctccat
    48781 atggatgtta tccaggaacg tttagagcgt gagttcaata ttgacctcat catgacagct
    48841 ccgtctgtta tttacaaagt taatttgacc gacggtgagt ctatggatgt gtctaaccca
    48901 tctgagtttc cagacccaac taagattgcg accattgaag agccttatgt caaggcgcaa
    48961 atcatggtac cacaggagtt cgtcggagca gtaatggagc tagctcagcg taagcgtggg
    49021 gactttgtga ctatggacta tattgatgat aaccgtgtca atgttatcta tcaaattcct
    49081 cttgctgaaa ttgtctttga cttctttgat aaacttaagt cttcgacacg tggttatgca
    49141 agctttgact acgaattgtc agaatatcgc ccatctaagc tggtgaaaat ggatattctt
    49201 ctcaatggag ataaggtgga tgccctcagc tttatcgttc acaaggactt tgcctacgaa
    49261 cgtgggaaac tcatcgttga taaactcaag aaaatcatcc ctcgccaaca atttgaagtt
    49321 ccaatccaag cggctattgg acacaagatt gtcgctcgta ctgatatcaa ggcccttcgt
    49381 aagaacgtac ttgctaaatg ttatggtggt gacgtttctc gtaagcgtaa actccttgaa
    49441 aaacaaaaag ctggtaagaa acgcatgaaa tccatcggat cagttgaagt tccgcaagaa
    49501 gccttcctca gcgtcttgag tatggatgaa gaataagtta tcagaaatgc ctttccttgt
    49561 tcacaggaaa tttataagaa tcaatagtaa agcaggctta gatggtctgc ttttttagtt
    49621 tttatactct tcgaaaatct cttcaaacca cgtcagcgtc gccttaccgt atgtatggtt
    49681 actgacttcg tcagtttcat ctacaacctc aaaaccatgt tttgagctga cttcgtcagt
    49741 ttcatctaca acctcaaaac tgtgttttga acaacctgcg gctagcttcc tagtttgctc
    49801 tttgattttc attgagtatt agaacagaaa aaatgcttgg agtatttgtt tgtgtgttta
    49861 cttttatata acaaactata aacacaacaa aaatataaaa aaagagacaa aaaagaacag
    49921 aaagtaatta acaacgattt catatagtgt tatacttata gcataaagtt aatggaaaga
    49981 agggaaaacc ttatggtatt agattatttc tttgacaaaa accttgtgtt ttgcttagaa
    50041 gcggataatc aagaataact ctttgatcag gtagcaagct tgttggagga acgagaaatt
    50101 gt
//
LOCUS       DAVBBO010000007        48474 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ST1
            SAMEA2066453-rid20184263.denovo.007, whole genome shotgun sequence.
ACCESSION   DAVBBO010000007 DAVBBO010000000
VERSION     DAVBBO010000007.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2066453
            Sequence Read Archive: ERR351777
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 48474)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 48474)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980402.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980402.1
            Genome Coverage       :: 176x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:17:33
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,141
            CDSs (total)                      :: 2,104
            Genes (coding)                    :: 1,953
            CDSs (with protein)               :: 1,953
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 16S)
            partial rRNAs                     :: 1 (23S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 151
            CDSs (without protein)            :: 151
            Pseudo Genes (ambiguous residues) :: 0 of 151
            Pseudo Genes (frameshifted)       :: 73 of 151
            Pseudo Genes (incomplete)         :: 76 of 151
            Pseudo Genes (internal stop)      :: 40 of 151
            Pseudo Genes (multiple problems)  :: 32 of 151
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..48474
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2066453-rid20184263.denovo.007"
                     /strain="ST1"
                     /db_xref="taxon:1313"
     gene            complement(308..1474)
                     /gene="recA"
                     /locus_tag="VQU30_000408"
     CDS             complement(308..1474)
                     /gene="recA"
                     /locus_tag="VQU30_000408"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397020.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase RecA"
                     /protein_id="HET2446585.1"
                     /translation="MAKKPKKLEEISKKFGAEREKALNDALKLIEKDFGKGSIMRLGE
                     RAEQKVQVMSSGSLALDIALGSGGYPKGRIIEIYGPESSGKTTVALHAVAQAQKEGGI
                     AAFIDAEHALDPAYAAALGVNIDELLLSQPDSGEQGLEIAGKLIDSGAVDLVVVDSVA
                     ALVPRAEIDGDIGDSHVGLQARMMSQAMRKLGASINKTKTIAIFINQLREKVGVMFGN
                     PETTPGGRALKFYASVRLDVRGNTQIKGTGDQKETNVGKETKIKVVKNKVAPPFKEAV
                     VEIMYGEGISKTGELLKIASDLDIIKKAGAWYSYKDEKIGQGSENAKKYLAEHPEIFD
                     EIDKQVRSKFGLIDGEEVSEQDTENKKDEPKKEEAVNEEVPLDLGDELEIEIEE"
     gene            complement(1529..2785)
                     /locus_tag="VQU30_000409"
     CDS             complement(1529..2785)
                     /locus_tag="VQU30_000409"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000642700.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence/damage-inducible protein A"
                     /protein_id="HET2446586.1"
                     /translation="MKAEIIAVGTEILTGQIVNTNAQFLSEKLAEIGVDVYFQTAVGD
                     NEVRLLSLLEIASQRSSLVILTGGLGPTEDDLTKQTLAKFLGKALVFDPQAQEKLDIF
                     FALRPDYARTPNNERQAQIVEGAIPLPNETGLAVGGKLEVDGVTYVVLPGPPSELKPM
                     VLNLLLPKLMTGSKLYSRVLRFFGIGESQLVTILADLIDNQVDPTLAPYAKTGEVTLR
                     LSTKASSQEEANQALDILENQILDCQTFEGISLRDFCYGYGEETSLASIVVEELKRQG
                     KTIAAAESLTAGLFQATVANFSGISSIFKGGFVTYSLEEKSRMLDIPAKNLEEHGVVS
                     EFTAQKMAEQARSKTQSDFGISLTGVAGPDSLEGHPVGTVFIGLAQDQGTEVIKVNIG
                     GRSRADVRHIAVMHAFNLVRKALLSD"
     gene            complement(2869..3885)
                     /locus_tag="VQU30_000410"
     CDS             complement(2869..3885)
                     /locus_tag="VQU30_000410"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000239264.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LCP family protein"
                     /protein_id="HET2446587.1"
                     /translation="MVKKIIGMVLALLSVTVVGVGVFAYTIYQQGTETLAKTYKKIGE
                     ETKVIEATEPLTILLMGVDTGNVERTETWVGRSDSMILMTVNPKTKKTTMMSLERDIL
                     TRIESGNGQAHEAKLNSAYADGGAELAIETIQKMMNIHIDRYVMVNMRGLQKLVDAVG
                     GITVNNILGFPISISDQEEFNTISIGVGEQHIGGEKALVYARMRYQDPEGDYGRQKRQ
                     REVIQKVMEKALSLNSVGHYQEILKALSDNMQTNIDLSAKSIPNLLGYKDSFKTIETQ
                     QLQGEGEILQGVSYQIVSRAHMLEMQNILRRSLGQEEVTQLETNAVLFEDLFGRAPVG
                     DEDN"
     gene            complement(3893..4411)
                     /locus_tag="VQU30_000411"
     CDS             complement(3893..4411)
                     /locus_tag="VQU30_000411"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000455540.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HET2446588.1"
                     /translation="MEYELLIREAEPKDAAELVAFLNRVSLETDFTSLDGDGILLTSE
                     EMEIFLNKQASSDNQITLLAFLNGKIAGIVNITADQRKRVRHIGDLFIVIGKRYWNNG
                     LGSLLLEEAIEWAQASGILRRLQLTVQTRNQAAVHLYQKHGFVIEGSQERGAYIEEGK
                     FIDVYLMGKLIG"
     gene            complement(4401..4844)
                     /gene="tsaE"
                     /locus_tag="VQU30_000412"
     CDS             complement(4401..4844)
                     /gene="tsaE"
                     /locus_tag="VQU30_000412"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000288243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     ATPase subunit type 1 TsaE"
                     /protein_id="HET2446589.1"
                     /translation="MYTKNEEELQALGERLGHLLAKNDVLILTGELGAGKTTFTKGLA
                     KGLQISQMIKSPTYTIVREYEGRLPLYHLDVYRIEGDADSIDLDEFIFGGGVTVIEWG
                     NLLGDALPDAYLELEILKEADGRRLNFQAKGLRAEKLLEELQYGV"
     gene            complement(4930..5550)
                     /locus_tag="VQU30_000413"
     CDS             complement(4930..5550)
                     /locus_tag="VQU30_000413"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000839915.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2446590.1"
                     /translation="MKSMRILFLLALIQISLSSCFLWKECILSFKQSTAFFIGSMVFV
                     SGICAGVNYLYTRKQEVHSVLASKKSVKLFYSMLLLINLLGAVLVLSDNLFIKNTLQQ
                     ELVDFLLPSFFFLFGLDLLIFLPLKKYVRDFLAMLDRKKTVLVTILATLLFLRNPMTI
                     VSLLIYIGLGLFFAAYLVPNSVKKEVSFYGHIFRDLVLVIVTLIFF"
     gene            complement(5933..6796)
                     /locus_tag="VQU30_000414"
                     /pseudo
     CDS             complement(5933..6796)
                     /locus_tag="VQU30_000414"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001093609.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
     gene            6961..7155
                     /locus_tag="VQU30_000415"
     CDS             6961..7155
                     /locus_tag="VQU30_000415"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2446591.1"
                     /translation="MKKKRVSRMKKNRGIQKLAILVLLGVFMFSNTIPYQQFIQKNRQ
                     LEIRVQSQKKSNGLDVGKAD"
     gene            7470..7766
                     /locus_tag="VQU30_000416"
     CDS             7470..7766
                     /locus_tag="VQU30_000416"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000911560.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactococcin 972 family bacteriocin"
                     /protein_id="HET2446592.1"
                     /translation="MLKFRKVVASSLAVLAFSLALPVLAVSHRGGEWTYGGHHDPNNW
                     GAFSNYYHGSQYHWAYVGSNGRNNQKTVYAGARSAAYAFVNTNFGEQVTFDAGW"
     gene            7869..9884
                     /locus_tag="VQU30_000417"
     CDS             7869..9884
                     /locus_tag="VQU30_000417"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677978.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin-associated integral membrane family
                     protein"
                     /protein_id="HET2446593.1"
                     /translation="MKKLFILISNLLASLFFVWVFTIWTDTYVSYYYPNVVVHDSSPE
                     TTFQHVATRLEKLAEETDSFIAIQHQDPNSEGTTVFSYTTFGDGKLPDGLQEKKLEDA
                     QSSSVETNYFVFDGHLDIHLLREELSQLGLTNMNLTIPSKLSTLMAIFSNGFQLISLL
                     IFILTFIALTLISQISQLRSSGIRLISGEKRWSIFLRPVGEDLKGIAVGFSLAGVLAI
                     LMQKILSLPTQSLMTIGAGLLSYNLILLSISLFFAQLFAVGIKKIHLMQIIKGQVPVR
                     GIISLILIGQLLAIIIVTLGIGSSLKYSQAWQQHRIGQEAWSQERQLITLSISREGTS
                     PGFDEQAQRKLRTWYQLMDLAVSEQKAFLSRHQLIDRTLQNGMASSKNLITSTEWHDY
                     NPNGNVLIVTPQYLERQNIPVDTTIEQKMNHLDVGEFVLLLPEHLRSEEEHYKSVFED
                     DLTSRMSSQDERQQMTATVGYLESGQDRFVYNTTPISYQQFLKDPIIIVITPQSTGPQ
                     SILFWIDAVQNYVLFNQLSDAQELIQRQGIENWVSEMQTGYHNYITLLDNIQRERWVM
                     LAGAGLGIATSILLFNTMNRLYFEEFRRAIFIKRIAGLRFLEIHRTYLFAQLGVFLLG
                     FVASVFLQVEIGVAFLVLLLFTGLSLLQLHVQMQKENKMSMLVLKGG"
     gene            9886..10518
                     /locus_tag="VQU30_000418"
     CDS             9886..10518
                     /locus_tag="VQU30_000418"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260353.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET2446594.1"
                     /translation="MIELKQVSKSFGERELFSNLSMTFEAGKVYALIGSSGSGKTTLM
                     NMIGKLEPYDGTIFYRGKDLANYKSSDFFRHELGYLFQNFGLIENQSIEENLKLGLIG
                     QKLSRSEQRLRQKQALEQVGLTYLDLDKRIFELSGGESQRVALAKVILKNPPFILADE
                     PTASIDPATSQLIMEILLSLRDDNRLIIIATHNPAIWEMADEVFTMDRLK"
     gene            10659..10937
                     /locus_tag="VQU30_000419"
     CDS             10659..10937
                     /locus_tag="VQU30_000419"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001843943.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence protein ComA"
                     /protein_id="HET2446595.1"
                     /translation="MKKFDNYIVEKPCDSNSDKLQKILIIENLVDDILQFPLRINNSV
                     GEIFLLQPFQKKTIFIPCYFEEDIVKVKDDDKVEWNLLEFQKFRAFLA"
     gene            complement(11446..11859)
                     /gene="ndk"
                     /locus_tag="VQU30_000420"
     CDS             complement(11446..11859)
                     /gene="ndk"
                     /locus_tag="VQU30_000420"
                     /EC_number="2.7.4.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000438285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside-diphosphate kinase"
                     /protein_id="HET2446596.1"
                     /translation="MEQTFFIIKPDGVKRGLVGEVLKRIEQRGFTIEKLEFRSQVSEE
                     LIDQHYQDLVGQSFYPPIREFMTSGPVLVGVISGPKVIETWRTMMGATRPEEALPGTI
                     RGDFAKAAGENEVIQNVVHGSDSEESAKREIALWF"
     gene            complement(11970..15647)
                     /gene="rpoC"
                     /locus_tag="VQU30_000421"
     CDS             complement(11970..15647)
                     /gene="rpoC"
                     /locus_tag="VQU30_000421"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000228741.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit beta'"
                     /protein_id="HET2446597.1"
                     /translation="MVDVNRFKSMQITLASPSKVRSWSYGEVKKPETINYRTLKPERE
                     GLFDEVIFGPTKDWECACGKYKRIRYRGIVCDRCGVEVTRTKVRRERMGHIELKAPVS
                     HIWYFKGIPSRMGLTLDMSPRALEEVIYFAAYVVIDPKDTPLEHKSIMTEREYRERLR
                     EYGYGSFVAKMGAEAIQDLLKQVDLEKEIAELKEELKTATGQKRVKAIRRLDVLDAFY
                     KSGNKPEWMILNILPVIPPDLRPMLQLDGGRFASSDLNDLYRRVINRNNRLARLLELN
                     APGIIVQNEKRMLQEAVDALIDNGRRGRPITGPGSRPLKSLSHMLKGKQGRFRQNLLG
                     KRVDFSGRSVIAVGPTLKMYQCGVPREMAIELFKPFVMREIVARDIVQNVKAAKRLVE
                     RGDERIWDILEEVIKEHPVLLNRAPTLHRLGIQAFEPVLIDGKALRLHPLVCEAYNAD
                     FDGDQMAIHVPLSEEAQAEARILMLAAEHILNPKDGKPVVTPSQDMVLGNYYLTMEEA
                     GREGEGMVFKDRDEAVMAYRNGYVHLHSRVGIATDSLNKPWTEEQRHKVLLTTVGKIL
                     FNDIMPEGLPYLQEPNNANLTEGVPAKYFLPLGGDIKEAISNLELNPPFKKKNLGNII
                     AEIFKRFRTTETSALLDRMKNLGYHHSTLAGLTVGIADIPVVDDKAEIIEESHKRVEQ
                     ITKQFRRGMITDDERYNAVTAEWRAAREKLEKRLIANQDPKNPIVMMMDSGARGNISN
                     FSQLAGMRGLMAAPNGRIMELPILSNFREGLSVLEMFFSTHGARKGMTDTALKTADSG
                     YLTRRLVDVAQDVIIREDDCGTDRGLLIRSIAEGKEMIESLEERLNGRYTKKTVKHPE
                     TGAVIIGPNELITEDKAREIVNAGVEEVTIRSVFTCNTRHGVCRHCYGINLATGDAVE
                     VGEAVGTIAAQSIGEPGTQLTMRTFHTGGVASNTDITQGLPRVQEIFEARNPKGEAVI
                     TEVKGEVTAIEEDASTRTKKVFVKGETGEGEYVVPFTARMRVEVGGQVARGAALTEGS
                     IQPKRLLAVRDVLSVETYLLGEVQKVYRSQGVEIGDKHIEVMVRQMIRKVRVMDPGDT
                     DLLMGTLMDINDFTDANKDVLIAGGVPATGRPVLMGITKASLETNSFLSAASFQETTR
                     VLTDAAIRGKKDHLLGLKENVIIGKIIPAGTGMARYRNLEPYAVNEEEYLNPPVEEEG
                     NEETTEVVVDTAVETVEETVE"
     gene            complement(15680..19291)
                     /gene="rpoB"
                     /locus_tag="VQU30_000422"
     CDS             complement(15680..19291)
                     /gene="rpoB"
                     /locus_tag="VQU30_000422"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000907130.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit beta"
                     /protein_id="HET2446598.1"
                     /translation="MAGHDVQYGKHRTRRSFSRIKEVLDLPNLIEIQTDSFKAFLDHG
                     LKEVFEDVLPISNFTDTMELEFVGYEIKEPKYTLEEARIHDASYSAPIFVTFRLINKE
                     TGEIKTQEVFFGDFPIMTEMGTFIINGGERIIVSQLVRSPGVYFNDKVDKNGKVGYGS
                     TVIPNRGAWLELESDSKDITYTRIDRTRKIPFTTLVRALGFSGDDEIFDIFGDSELVR
                     NTVEKDIHKNPMDSRTDEALKEIYERLRPGEPKTAESSRSLLVARFFDPRRYDLAAVG
                     RYKINKKLNVKTRLLNQTIAEPLVDPETGEILVEAGTIMTRSVIESIESHLDGDLNKI
                     VYIPNDAAVVTEPVVLQKFKVVAPTDPDRVVTIIGNANPDDKVRTVTPADILAEMSYF
                     LNLAEGLGRVDDIDHLGNRRIRAVGELLANQVRLGLSRMERNVRERMSVQDNEVLTPQ
                     QIINIRPVTAAVKEFFGSSQLSQFMDQHNPLSELSHKRRLSALGPGGLTRDRAGYEVR
                     DVHYTHYGRMCPIETPEGPNIGLINNLSSYGHLNKYGFVQTPYRKVDRETGVVTNEIV
                     WLTADEEDEYTVAQANSSLNEDGTFAEKIVMGRHQGVNQEYPANIVDYMDVSPKQVVA
                     VATACIPFLENDDSNRALMGANMQRQAVPLINPQAPYVGTGMEYQAAHDSGAAVIAQY
                     DGKVTYADADKVEVRREDGSLDVYHIQKFRRSNSGTAYNQRTLVKVGDVVEKGDFIAD
                     GPSMENGEMALGQNPIVAYMTWEGYNFEDAVIMSERLVKDDVYTSVHLEEYESETRDT
                     KLGPEEITREIPNVGEDALKDLDEMGIIRIGAEVKEGDILVGKVTPKGEKDLSAEERL
                     LHAIFGDKSREVRDTSLRVPHGADGVVRDVKIFTRVNGDELQSGVNMLVRVYIAQKRK
                     IKVGDKMAGRHGNKGVVSRIVPVEDMPYLPDGTPVDIMLNPLGVPSRMNIGQVMELHL
                     GMAARTLGIHIATPVFDGASSEDLWSTVKEAGMDSDAKTILYDGRTGEPFDNRVSVGV
                     MYMIKLHHMVDDKLHARSVGPYSTVTQQPLGGKAQFGGQRFGEMEVWALEAYGASNVL
                     QEILTYKSDDINGRLKAYEAITKGKPIPKPGVPESFRVLVKELQSLGLDMRVLDEDDQ
                     EVELRDLDEGMDEDVIHVDDLEKAREKAAQEAKAAFEAEEAEKATKAEATEEAAEQE"
     gene            19707..19777
                     /locus_tag="VQU30_000423"
     tRNA            19707..19777
                     /locus_tag="VQU30_000423"
                     /product="tRNA-Cys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:19739..19741,aa:Cys,seq:gca)
     gene            complement(19975..21306)
                     /locus_tag="VQU30_000424"
     CDS             complement(19975..21306)
                     /locus_tag="VQU30_000424"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000390004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HlyC/CorC family transporter"
                     /protein_id="HET2446599.1"
                     /translation="MEDPSSQNLLLQFVLLFILTVLNAFFSATEMAMVSLNRARVEQK
                     AEEGDRRYIRLLKVLENPNHFLSTIQVGITLITILSGASLTDTLGRVIASWLGNGETA
                     QAVATFLSLAFLTYISIVFGELYPKRIALNLKDALAIRTAPVIIGIGKLVSPFVWLLA
                     ASTNFLSHLTPMSFDDADEKMTRDEIAYMLTNSEETLDADEIEMLQGVFSLDELMARE
                     VMVPRTDAFMVDIQDDSQAIIQSILKQNYSRIPVYDGDKDNVIGIIHTKSLLKAGFVD
                     GFDNIVWKRILQDPLFVPETIFVDDLLKELRNTQRQMAILLDEYGGMAGLVTLEDLLE
                     EIVGEIDDETDKAAIDVHQIGEDTYIVQGTMTLNDFNNYFNVELESDDVDTIAGYYLT
                     GVGTIPTTEKLSYELVSQNKQFILTNDKVKNGRVTKVKVQITEVEIEEETE"
     gene            complement(21597..22421)
                     /gene="endA"
                     /locus_tag="VQU30_000425"
     CDS             complement(21597..22421)
                     /gene="endA"
                     /locus_tag="VQU30_000425"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001036779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-entry nuclease EndA"
                     /protein_id="HET2446600.1"
                     /translation="MNKKTRQTLIGLLVLLLLSTGSYYIKQMQSTANSPKTKLSQKKQ
                     APEAPSQALAESVLTDAVKSQIKGSLEWNGSGAFIVNGNKTNLDAKVSSKPYADNKTK
                     TVGKETVPTVANALLSKATRQYKNRKETGNGSTSWTPPGWHQVKNLKGSYTHAVDRGH
                     LLGYALIGGLDGFDASTSNPKNIAVQTAWANQAQAEYSTGQNYYESKVRKALDQNKRV
                     RYRVTLYYASNEDLVPSASQIEAKSSDGELEFNVLVPNVQKGLQLDYRTGEVTVTQ"
     gene            complement(22460..22648)
                     /locus_tag="VQU30_000426"
     CDS             complement(22460..22648)
                     /locus_tag="VQU30_000426"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004245549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit beta"
                     /protein_id="HET2446601.1"
                     /translation="MNKKSSYVVKRLLLVIIVLILGTLALGIGLMVGYGILGKGQDSW
                     AILSPAKWQELIHKFTGN"
     gene            complement(22641..23924)
                     /gene="murA"
                     /locus_tag="VQU30_000427"
     CDS             complement(22641..23924)
                     /gene="murA"
                     /locus_tag="VQU30_000427"
                     /EC_number="2.5.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397009.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine
                     1-carboxyvinyltransferase"
                     /protein_id="HET2446602.1"
                     /translation="MDKIVVQGGDNRLVGSVTIEGAKNAVLPLLAATILASEGKTVLQ
                     NVPILSDVFIMNQVVGGLNAKVDFDEEAHLVKVDATGDITEEAPYKYVSKMRASIVVL
                     GPILARVGHAKVSMPGGCTIGSRPIDLHLKGLEAMGVKISQTAGYIEAKAERLHGAHI
                     YMDFPSVGATQNLMMAATLADGVTVIENAAREPEIVDLAILLNEMGAKVKGAGTETIT
                     ITGVEKLHGTTHNVVQDRIEAGTFMVAAAMTGGDVLIRDAVWEHNRPLIAKLLEMGVE
                     VIEEDEGIRVRSQLENLKAVHVKTLPHPGFPTDMQAQFTALMTVAKGESTMVETVFEN
                     RFQHLEEMRRMGLHSEIIRDTARIVGGQPLQGAEVLSTDLRASAALILTGLVAQGETV
                     VGKLVHLDRGYYGFHEKLAQLGAKIQRIEASDEDE"
     gene            complement(23948..24178)
                     /locus_tag="VQU30_000428"
     CDS             complement(23948..24178)
                     /locus_tag="VQU30_000428"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014017351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1146 domain-containing protein"
                     /protein_id="HET2446603.1"
                     /translation="MVQLLFTLSSHMLFIYVSFYLLKDLVRWEKVLKVTAENTRKVRV
                     LVAFFSIVIGYILSSFFISLYHLWQEALRGLL"
     gene            complement(24236..25273)
                     /locus_tag="VQU30_000429"
     CDS             complement(24236..25273)
                     /locus_tag="VQU30_000429"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001813016.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PDZ domain-containing protein"
                     /protein_id="HET2446604.1"
                     /translation="MKKKIRWPLYVIAALIVTFLAFVVPLPYYIEVPGGSEDIRQVLK
                     VNDTEDKEAGAYQFVTVGVQHATLAHMIYAWLTPFTDIRSAQETTGGSSDVEFMRINQ
                     FYMQTSQNMAKYQGLKTAGKDIELKYFGVYVLNVTDNSTFKGILNISDTVTAVNDQTF
                     DSSKDLIDYVSSQKLGDSVKVTYEEDGQTKSAEGKIITLENGKNGIGIGLIDRTEVIS
                     NVPISFSTAGIGGPSAGLMFSLAIYTQIAHPDLRNGRIVAGTGTIDRDGNVGDIGGID
                     KKVVASARAGAAIFFAPDNPVSEEEQKAHPDAKNNYQTALEAAKTIKTDMKIVPVKTL
                     QDAIDYLKNNP"
     gene            complement(25257..25745)
                     /gene="coaD"
                     /locus_tag="VQU30_000430"
     CDS             complement(25257..25745)
                     /gene="coaD"
                     /locus_tag="VQU30_000430"
                     /EC_number="2.7.7.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001280753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pantetheine-phosphate adenylyltransferase"
                     /protein_id="HET2446605.1"
                     /translation="MSDKIGLFTGSFDPMTNGHLDIIERASRLFDKLCVGIFFNPHKQ
                     GFLPLENRKRGLEKALGHLENVEVVASHDELVVDVAKRLGATCLVRGLRNASDLQYEA
                     SFDYYNHQLSSDIETIYLHSRPEHLYISSSGVRELLKFGQDIACYVPESILEEIRNEK
                     KD"
     gene            complement(25735..26274)
                     /gene="rsmD"
                     /locus_tag="VQU30_000431"
     CDS             complement(25735..26274)
                     /gene="rsmD"
                     /locus_tag="VQU30_000431"
                     /EC_number="2.1.1.171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006147838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (guanine(966)-N(2))-methyltransferase
                     RsmD"
                     /protein_id="HET2446606.1"
                     /translation="MKIVSGIYGGRPLKTLEGKTTRPTSDKVRGAIFNMIGPYFEVGR
                     VLDLYAGSGGLSIEAVSRGMSSAVLVERDRKAQTIVAENIQMTKEVGKFQLLKMDAER
                     ALEQVSGEFDLVFLDPPYAKEQIVADIEKMAERELFSEDVMVVCETDKTVELPEEIAC
                     LGIWKEKIYGISKVTVYVR"
     gene            complement(26339..27331)
                     /locus_tag="VQU30_000432"
     CDS             complement(26339..27331)
                     /locus_tag="VQU30_000432"
                     /EC_number="6.3.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016502595.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate--ammonia ligase"
                     /protein_id="HET2446607.1"
                     /translation="MKKSFIHQQEEISFVKNTFTQYLKDKLEVVEVQGPILSKVGDGM
                     QDNLSGVENPVSVKVLQIPDATYEVVHSLAKWKRHTLARFGFGEGEGLFVHMKALRPD
                     EDSLDATHSVYVDQWDWEKVIPNGKRNIVYLKETVEKIYKAIRLTELAVEARYDIESI
                     LPKQITFIHTEELVERYPDLTPKERENAICKEFGAVFLIGIGGELPDGKPHDGRAPDY
                     DDWTSESENGYKGLNGDILVWNESLGGAFELSSMGIRVDEETLRRQVEITGDEDRLEL
                     EWHKSLLNGLFPLTIGGGIGQSRMAMFLLRKRHIGEVQTSVWPQEVRDTYENIL"
     gene            complement(27443..28126)
                     /locus_tag="VQU30_000433"
     CDS             complement(27443..28126)
                     /locus_tag="VQU30_000433"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015545711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Bax inhibitor-1/YccA family protein"
                     /protein_id="HET2446608.1"
                     /translation="MNHTIIHDRAGLNQFYAKVYAFVGLGIGLSALVSGLMLTVFQSQ
                     LVYLLMQGRLWLTIATFAELALVFVASSMASRNSPAALPVFLLYSVLNGFTLSFVVAF
                     YTPGTVLSAFVSSALLFFVMAAVGIFTKKDLSGIGRAMMAALIGLLIAMVVNIFLASG
                     FFDYMISVAMVLVFSGLIAWDNQKIRLAYEQSQGRVATGWVVSMALSIYLDFINLFLS
                     ILRIFGRND"
     gene            complement(28182..28922)
                     /locus_tag="VQU30_000434"
     CDS             complement(28182..28922)
                     /locus_tag="VQU30_000434"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000152696.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA methyltransferase"
                     /protein_id="HET2446609.1"
                     /translation="MTIITSKANSVVKNAKKLHQKKYRKSAYLIEGWHLFEEAVQAGV
                     TIEKIFALENYRNQLAAFPQTVWISEDILLDLADSQTPQGIVAVVQKEEVGQADLSQG
                     KFLFLEDVQDPGNVGTIIRTADAAGFTGVIVSDKSADIYSLKTLRSMQGSHFHLPIYR
                     MTSQALLDETKKVAIPVLATTLSKDSVDYRELPSIENFVLVMGNEGQGISPLMAESAD
                     QLVHISMKGQAESLNVAVAAGILIFHLS"
     gene            28956..29234
                     /locus_tag="VQU30_000435"
     CDS             28956..29234
                     /locus_tag="VQU30_000435"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001174612.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acylphosphatase"
                     /protein_id="HET2446610.1"
                     /translation="MQKVRMIAQGRVQGVGFRWGVYSLALEIGGITGRVWNNDDGTVE
                     ILAQADSSAIMAKFIQEIRKGPTPFSKVSYLDVKLSNFPPYSDFKIAN"
     gene            29312..30238
                     /gene="yidC"
                     /locus_tag="VQU30_000436"
     CDS             29312..30238
                     /gene="yidC"
                     /locus_tag="VQU30_000436"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000835957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein insertase YidC"
                     /protein_id="HET2446611.1"
                     /translation="MKSIKRFAFSAMGVAMLLVLTGCVNVDKTTGQPTGFIWNTIGAP
                     MAEAIKYFATDKGLGFGVAIIIVTIIVRLIILPLGIYQSWKATLHSEKMNALKHVLEP
                     HQTRLKEATTQEEKLEAQQALFAAQKEHGISMFGGVGCFPILLQMPFFSAIYFAAQHT
                     EGVAQASYLGIPLGSPSMILVACAGVLYYLQSLLSLHGVEDEMQREQIKKMIYMSPLM
                     IVVFSLFSPASVTLYWVVGGFMMILQQFIVNYIVRPKLRKKVREELAKNPPKASAFSK
                     PSGRKDVTPEQPTAITSKKKHKNRNAGKQRSR"
     gene            complement(30313..31107)
                     /gene="pflA"
                     /locus_tag="VQU30_000437"
     CDS             complement(30313..31107)
                     /gene="pflA"
                     /locus_tag="VQU30_000437"
                     /EC_number="1.97.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001288284.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate formate lyase-activating protein"
                     /protein_id="HET2446612.1"
                     /translation="MSEETIDYGQVTGMVHSTESFGSVDGPGIRFIVFLQGCHMRCQY
                     CHNPDTWAMESNKSRERTVDDVLTEALRYRGFWGNKGGITVSGGEALLQIDFLIALFT
                     KAKEQGIHCTLDTCALPFRNKPRYLEKFDKLMAVTDLVLLDIKEINEEQHKIVTSQTN
                     KNILACAQYLSDIGKPVWIRHVLVPGLTDRDDDLIELGKFVKTLKNVDKFEILPYHTM
                     GEFKWRELGIPYSLEGVKPPTADRVKNAKKLMDTESYQDYMKRVHG"
     gene            complement(31233..32483)
                     /locus_tag="VQU30_000438"
     CDS             complement(31233..32483)
                     /locus_tag="VQU30_000438"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000856498.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diaminopimelate decarboxylase"
                     /protein_id="HET2446613.1"
                     /translation="MKTPFINREELEAIVAEFPTPFHLYDEKGIREKARAVNQAFSWN
                     KGFKEYFAVKATPTPAILKILQEEGCGVDCSSYVELLMSHKLDFLGSEIMFSSNNTPD
                     KEYAYARELGATINLDAFEDIEHLERVAGIPEIISCRYNPGGVFELGTDIMDNPGEAK
                     FGMTKDQLFEAFAILKEKGAKTFGIHSFLASNTVTHLYYPELARQLFELAVEIKEKLG
                     ISLDFINLSGGIGVNYRPDQEPNDIALIGEGVRKVYEEVLTSAGLGQVKIFTELGRFM
                     LAPHGALVTRVTHKKETYRTYLGVDASAVNLMRPAMYGAYHHISNVTHPDGPAEAVDV
                     VGSLCENNDKFAVNRELPHTEIGDLLVIHDTGAHGFSMGYQYNAKLRSAEILYTEEGK
                     ARQIRRAERPEDYFATLYGFDFEE"
     gene            complement(32550..33377)
                     /gene="purR"
                     /locus_tag="VQU30_000439"
     CDS             complement(32550..33377)
                     /gene="purR"
                     /locus_tag="VQU30_000439"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004242125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pur operon repressor"
                     /protein_id="HET2446614.1"
                     /translation="MKLRRSDRMVVISNYLINNPYKLTSLNTFAEKYESAKSSISEDI
                     VIIKRAFEEIEIGHIQTVTGAGGGVIFTPSISSQDAKEMVEDLRTKLSESDRILPGGY
                     IYLSDLLSTPAILKNIGRIIAKSFMDQKIDAVMTVATKGVPLANAVANVLNVSFVIVR
                     RDLKITEGSTVSVNYVSGSSGDRIEKMFLSKRSLKAGSRVLIVDDFLKGGGTVNGMIS
                     LLHEFDSELAGVAVFADNAQEEREKQFDYKSLLKVTNIDVKNQAIDVEVGNIFDEDK"
     gene            complement(33644..34585)
                     /locus_tag="VQU30_000440"
     CDS             complement(33644..34585)
                     /locus_tag="VQU30_000440"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3'-5' exoribonuclease YhaM family protein"
                     /protein_id="HET2446615.1"
                     /translation="MKISHMKKDELFEGFYLIKSADLRQTRAGKNYLAFTFQDDSGEI
                     DGKLWDAQPHNIEAFTAGKVVHMKGRREVYNNTPQVNQITLRLPQAGEPNDPADFKVK
                     SPVDVKEIRDYMSQMIFKIENPVWQRIVRNLYTKYDKEFYSYPAAKTNHHAFETGLAY
                     HTATMVRLADAISEVYPQLNKSLLYAGIMLHDLAKVIELTGPDQTEYTVRGNLLGHIA
                     LIDSEITKTVMELGIDDTKEEVVLLRHVILSHHGLLEYGSPVRPRIMEAEIIHMIDNL
                     DASMMMMSTALALVDKGEMTNKIFAMDNRSFYKPDLD"
     gene            complement(34575..35831)
                     /locus_tag="VQU30_000441"
     CDS             complement(34575..35831)
                     /locus_tag="VQU30_000441"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000444769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA recombination protein RmuC"
                     /protein_id="HET2446616.1"
                     /translation="MESLLILLLIANLAGLFLIWQRQDRQEKHLSKSLEDQADHLSDQ
                     LDYRFDQARQASQLDQKDLEVVVSDRLQEVRIELHQGLTQVRQEMTDNLLQTRDKTDQ
                     RLQALQESNEQRLEQMRQTVEEKLEKTLQTRLQASFETVSKQLESVNRGLGEMQTVAR
                     DVGALNKVLSGTKTRGILGELQLGQIIEDIMTPAQYEREYATVENSSERVEYAIKLPG
                     QGDQEYVYLPIDSKFPLADYYRLEEAYETGDKDEIERCRKSLLASVKRFARDIRNKYI
                     APPRTTNFGILFVPTEGLYSEIVRNPVFFDDLRREEQIIVAGPSTLSALLNSLSVGFK
                     TLNIQKSADHISKTLASVKTEFGKFGGILVKAQKHLQHASGNIDELLNRRTIAIERTL
                     RHIELSEGEPALDLLHFQENEEEYED"
     gene            complement(35833..36495)
                     /locus_tag="VQU30_000442"
     CDS             complement(35833..36495)
                     /locus_tag="VQU30_000442"
                     /EC_number="2.7.6.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000006147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine diphosphokinase"
                     /protein_id="HET2446617.1"
                     /translation="MSEYKLSENNWTRVAVFAGGDRGHYRTDFDGFVGVDRGSLWILE
                     EDLPLALAVGDFDSVTEEERQVIQKRAQYFVQARPEKDDTDLELALLTIFKQNPQAQV
                     TIFGALGGRIDHMLANVFLPSNPKLASYMHQIEIEDGQNLITYCPEGISQLEPRSDYD
                     YLAFMPVRDSQLTILGAKYELTEENFFFKKVYASNEYIDREVSVTCPDGYVVVLHSKD
                     RR"
     gene            complement(36458..37114)
                     /locus_tag="VQU30_000443"
     CDS             complement(36458..37114)
                     /locus_tag="VQU30_000443"
                     /EC_number="5.1.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007522408.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribulose-phosphate 3-epimerase"
                     /protein_id="HET2446618.1"
                     /translation="MSQYKIAPSILAADYANFEREIKRLEATGAEYAHIDIMDGHFVP
                     QISFGAGVVEALRPHSKMVFDCHLMVSNPEHHLEDFVRAGADIISIHVEATPHIHGAL
                     QKIRSLGVKPSVVINPGTPVEAIKHVLHLVDQVLVMTVNPGFGGQAFLPETMDKVREL
                     VALRDEKGLNFEIEVDGGIDDQTIAQAKEAGATVFVAGSYVFKGDVNERVQTLRKQLD
                     "
     gene            complement(37125..38003)
                     /gene="rsgA"
                     /locus_tag="VQU30_000444"
     CDS             complement(37125..38003)
                     /gene="rsgA"
                     /locus_tag="VQU30_000444"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome small subunit-dependent GTPase A"
                     /protein_id="HET2446619.1"
                     /translation="MQGQIIKALAGFYYVESDGQVYQTRARGNFRKKGHTPYVGDWVD
                     FSAEENSEGYILKIHERKNSLVRPPIVNIDQAVVIMSVKEPDFNSNLLDRFLVLLEHK
                     GIHPIVYISKMDLLEDGGELDFYQQTYGDIGYDFVTSKEELLPLLTGKVTVFMGQTGV
                     GKSTLLNKIAPDLNLETGEISDSLGRGRHTTRAVSFYNLNGGKIADTPGFSSLDYEVS
                     TAEDLNQAFPEIATVSRDCKFRTCTHTHEPSCAVKPAVEEGTIAPFRFDNYLQFLSEI
                     ENRRETYKKVSKKIPK"
     gene            complement(38596..39369)
                     /locus_tag="VQU30_000445"
     CDS             complement(38596..39369)
                     /locus_tag="VQU30_000445"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001227792.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell surface protein"
                     /protein_id="HET2446620.1"
                     /translation="MRKKLVNSLMCAVVLSGFPIATYANEKNIGPNITVSNGQTRLSI
                     PEKNGVEVIQSEENRVVYEVKEAAKIETSDGDMVAPIVVDSRITSINNQVVQGKTVYT
                     ADLEKATFVEEGYNKLAKPTNILDHIFGIQKVHAYTQNITTHQSQFDSTYSVELYTVV
                     HWVSYDGGVQKNITKISGGVDFHERDIEIESSSVEVRQGGWYSSQQKWFHPGARSSWE
                     YSTGFSKVGPGENRVVTNYTVNLIRYGDRWSAYLQNNPW"
     gene            complement(40059..40931)
                     /gene="rsmA"
                     /locus_tag="VQU30_000446"
     CDS             complement(40059..40931)
                     /gene="rsmA"
                     /locus_tag="VQU30_000446"
                     /EC_number="2.1.1.182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA
                     (adenine(1518)-N(6)/adenine(1519)-N(6))-
                     dimethyltransferase RsmA"
                     /protein_id="HET2446621.1"
                     /translation="MRIADYSVTKAVLERHGFTFKKSFGQNFLTDTNILQKIVDTAEI
                     DDQVNVIEIGPGIGALTEFLAERAAEVMAFEIDHRLVPILADTLRDFDNVTVVNEDIL
                     KVDLAQHIQNFKNPDLPIKVVANLPYYITTPILMHLIESGIPFSEFVVMMQKEVADRI
                     SAQPNTKAYGSLSIAVQYYMTAKVAFIVPRTVFVPAPNVDSAILKMVRRPVPAVAVED
                     ENFFFKVSKASFTHRRKTLWNNLTGYFGKTEEVKDKLTKALDQAGLSPSVRGEALSLE
                     EFASLADALKGQGL"
     gene            complement(41182..41400)
                     /locus_tag="VQU30_000447"
     CDS             complement(41182..41400)
                     /locus_tag="VQU30_000447"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000429598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2446622.1"
                     /translation="MENMTNPLLLVQIRVHGYLLDFASSEGQRQKHYRLKNLPQTVEL
                     TVDDVEEDVDLTLPENRSYQEADFFDTQ"
     gene            complement(41468..42109)
                     /locus_tag="VQU30_000448"
     CDS             complement(41468..42109)
                     /locus_tag="VQU30_000448"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000565534.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET2446623.1"
                     /translation="MIDIQGLEKKFNDRAIFSGLNLKLEKGKVYALIGKSGSGKTTLL
                     NILGKLEKIDGGRVLYQGKDLKTIPTREYFRDQMGYLFQNFGLLENQSIKENLDLGFV
                     GQKISKVERLERQVGALEKVNLGYLDLEQKIYTLSGGEAQRVALAKTILKNPPLILAD
                     EPTAALDPENSEEVMNLLVDLKDENRIIIIATHNPLVWNKADEIIDMRKLAHV"
     gene            complement(42111..44141)
                     /locus_tag="VQU30_000449"
     CDS             complement(42111..44141)
                     /locus_tag="VQU30_000449"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000825281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin-associated integral membrane family
                     protein"
                     /protein_id="HET2446624.1"
                     /translation="MKRLFILISMVLVSLYMVITSVDHREEILFGNYPSVDVTGMMIN
                     QPVASREEVTEVLSHLAVEHNSLIARRIVEPNEAGETLFTYATYGEGELPEGLTISSK
                     ESAETSDLLGSYLIVSGSLDGVSLQTTLKELGYQGFVSNGEDPFSIVLLLAATPMVLL
                     SLAIFLLTFMSLTLIYRIKSLRQAGIRLIAGESLFGVALRPVLEDVRQFICSVLVSSL
                     LGLGILWYQGALFMATVQLVIIALLLYGLTLAGISTLLSVVYLLGLQENSLVDLLKGK
                     LPLKRMMTLMMVGQLLAVLVVGSSATALLPHYREMQEMERASNKWSQSSDRYRLSFGW
                     SSAFADEEGTRKDNREWQTFTEERLANTDSFYIMSNVDNFSDGAEVDLDGNRLSDYTP
                     SGNVIYVSPRYLIEEKITVSSEFMDKMQNLSEGEFGLILPESLREQSTYYQRLFTDYL
                     QNFSSESVEVTSQKYYLPQVSLAFTETGQERFLYNDGYKTTRQYLKDPIIVVLTPQAT
                     GTRPVAGMLWGTTANSALKLDRYGDSITALKEQGLYHKVSYLVKSQLFFAKVLNDKRV
                     EFYSLLIGTILTLSTAILLFDSMNLLYFEQFRRELMIKRLAGMTIYELHGKYLLAQGG
                     VLLLGLVLSSILTRDGLISALVVALFTLNALLILVRQDKKEEAGSMAVLKGK"
     gene            complement(44410..45309)
                     /locus_tag="VQU30_000450"
     CDS             complement(44410..45309)
                     /locus_tag="VQU30_000450"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000904853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HET2446625.1"
                     /translation="MLIGQKIKEIRIEKGVSRPYFCGDEQELTVRQLSRIESGASQPS
                     LPKLAYIARRLGVPVYSLMPDFSALPPAYLELKYQILREPIYGKEEEYDKKEACLEEI
                     YKTYFDNLPKEEQLACEVLQACLDTSRTRRPEYAELILEEHMSQIIEKEVYSTNDMLL
                     IRLFFYQMLIRKDLAKFINQIEKLMLFLLEQKKVTKLENFFIIRDTLISGMCCLEKVG
                     VTDCFNDYLSCLQEIMDKTQDYQKKPLVFMFLWKQALREERDFSLAESFYQSSKTFAK
                     LIGDGFLVKKLTEEWQEDVKKYL"
     gene            complement(45381..45941)
                     /gene="rnmV"
                     /locus_tag="VQU30_000451"
     CDS             complement(45381..45941)
                     /gene="rnmV"
                     /locus_tag="VQU30_000451"
                     /EC_number="3.1.26.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000660004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease M5"
                     /protein_id="HET2446626.1"
                     /translation="MKEKISQVIVVEGRDDTVNLKRYFDVETYETRGSAINAQDIERI
                     QRLHQRQGVIVFTDPDFNGERIRRMIMTAIPTVRHAFLKRDEAVPKSKTKGRSLGIEH
                     ASYEDLKTALAQVTEQFEHESQFDISRSDLIRLGFLAGADSRKRREYLGETLRIGYSN
                     GKQLLKRLELFGVTLAEVEEAMKSYE"
     gene            complement(45941..46714)
                     /locus_tag="VQU30_000452"
     CDS             complement(45941..46714)
                     /locus_tag="VQU30_000452"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000575597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TatD family hydrolase"
                     /protein_id="HET2446627.1"
                     /translation="MIFDTHTHLNVEEFAGREAEEIALAAEMGVTQMNIVGFDKPTIE
                     RALELVDEYDQLYATIGWHPTEAGTYTEEVEAYLLDKLKHPKVVALGEIGLDYHWMTA
                     PKEVQEQVFRRQIQLSKDLDLPFVVHTRDALEDTYEIIKSEGVGPRGGIMHSFSGTLE
                     WAEKFVDLGMTISFSGVVTFKKVTDLQEAAKELPLDKILVETDAPYLAPVPKRGRENK
                     TAYTRYVVDFIADLRGMTTEELAVATTANAERIFGLDSK"
     gene            complement(47019..47912)
                     /locus_tag="VQU30_000453"
     CDS             complement(47019..47912)
                     /locus_tag="VQU30_000453"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001816585.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1542 domain-containing protein"
                     /protein_id="HET2446628.1"
                     /translation="MVAQDPKAQDSTKPTAEKSTVKAPAQRVDVKDITHLTDEEKVKV
                     AILQANGSALDGATINVAGDGTATITFPDGSVVTILGKDTVQQSAKGESVTQEATPEY
                     KLENTPGGDKGGNTGSSDANANAGGGSQAGGSAHTGSQNSAQSQASKQLATEKESAKN
                     AIEKAAKDKQDEIKGAPLSDKEKAELLARVEAEKQAALKEIENAKTMEDVKEAETIGV
                     QAIVMVTVPKRPVAPNAAPKTTSAPQATAGTMQDVTYQSPAGKQLPNTGSASSAALAS
                     LGLVVATSGFALLGRKTRRRK"
     gene            complement(48196..48330)
                     /gene="rpmH"
                     /locus_tag="VQU30_000454"
     CDS             complement(48196..48330)
                     /gene="rpmH"
                     /locus_tag="VQU30_000454"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000831903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L34"
                     /protein_id="HET2446629.1"
                     /translation="MKRTYQPSKLRRARKHGFRNRMSTKNGRRVLAARRRKGRKVLAA
                     "
BASE COUNT        13990 a        10915 c         9042 g        14527 t
ORIGIN      
        1 taaagctatt atatcagctt tccagaggag cgacaagaaa cagcaaactt atatatagcg
       61 gaatgaaata aggaaagtca aatcgatttt taacaatgtt ttagaagtag atatgtacta
      121 ttctagtttc gatctattat agttggttga gtttggaata gtacgctgta gctgctaaaa
      181 catttctaga aattaatttg actttcctaa tagagttgtt catatcttat ttcaagctac
      241 tatatataat ctaaaaactt gaatcaaaaa tcgaaaaagt agcggatttc tccactgctt
      301 taacagctta ttcttcaatt tcgatttcaa gttcatcgcc taagtcaagc ggaacttctt
      361 cattcactgc ttcttctttc tttggctcat cttttttgtt ttcagtatct tgttctgaaa
      421 cttcttctcc atcaatcaag ccaaatttag aacggacttg cttatcaatt tcatcaaaga
      481 tttctgggtg ctctgccaag tatttcttag cattctcaga accttgccca attttttcat
      541 ctttgtaaga ataccaagcc cctgcttttt tgataatatc caaatcgctt gcaatcttca
      601 aaagctcacc agtcttagaa attccttctc cgtacataat ttcaactacg gcttccttaa
      661 acggtggagc taccttattt tttacaacct taatcttagt ttctttaccg acattggttt
      721 ctttttggtc accagttccc ttaatttgtg tattaccacg aacatccaag cggactgaag
      781 catagaattt caaagcacgt ccgcccggtg ttgtttctgg atttccaaac atcactccaa
      841 ctttttcacg caattggttg ataaaaatgg caattgtttt ggttttattg atagaggcgc
      901 caagtttacg catggcctgg ctcatcatac gagcctgcaa accaacatgg ctatctccga
      961 tatctccatc aatttccgca cgaggaacaa gggcagcaac tgagtcgact acgacaagat
     1021 caactgcacc tgagtcaatc aattttcccg caatctcaag accttgctct cctgagtctg
     1081 gttgagacaa gagcaattcg tcaatattga caccaagggc cgcagcataa gctggatcaa
     1141 gggcatgttc cgcatcgata aaagcagcaa tcccaccttc tttttgcgct tgtgcaactg
     1201 catgaagggc aaccgttgtc ttaccagatg actctgggcc atagatttcg atgatacgtc
     1261 ccttaggata accacctgag ccaagggcaa tgtcaagagc taaagaacct gagctcatca
     1321 cttgcacctt ttgctccgca cgttcaccca aacgcatgat tgatccttta ccaaagtctt
     1381 tctcaatcaa tttaagagcg tcattcaagg ccttttcacg ttctgcccca aatttttttg
     1441 aaatttcttc taattttttt ggttttttcg ccattctatt ctcctacatt ctaatgatcc
     1501 tcagacctat ctactattat atcaaaaatt agtcacttaa taaagccttg cgaactaggt
     1561 taaaggcatg cataaccgca atgtgacgta catctgctcg gcttctgcct ccaatattaa
     1621 ccttgataac ctcagttcct tgatcttgcg ccaagcctat gaagactgtc ccaactgggt
     1681 gtccttctag gctatctggt cctgccactc cagtcaaact aattccaaaa tcagactggg
     1741 tcttgcttcg tgcctgctca gccatcttct gagctgtaaa ttcagacacc acaccatgtt
     1801 cttccaaatt cttggcagga atatccaaca tccttgattt ttcctccaag ctataggtca
     1861 caaaaccacc cttaaatata cttgaaattc cagaaaaatt cgccacggta gcttggaaaa
     1921 gacctgccgt caaactctct gcagccgcga tggttttccc ttgccttttc agttcttcta
     1981 ccacaatgct ggctaaacta gtttcttccc cataaccata gcaaaagtct cgtaaagaaa
     2041 ttccttcgaa agtctggcag tccaagattt gattttccaa gatatccagc gcttgattcg
     2101 cctcttcttg actgctagcc tttgttgaca gacgtagagt gacttctcct gtcttggcat
     2161 aaggggccaa ggtaggatcg acctgattat caattaaatc agccaaaatc gtaaccagct
     2221 ggctctcgcc aatcccaaag aaacgaagaa ctcgggaata cagcttgctc cctgtcatca
     2281 acttgggtag aagtaggttt aagaccatgg gtttcaattc acttggcgga cctggaagga
     2341 cgacataggt cactccgtct acttctaatt ttcctccaac agccagtcct gtttcgtttg
     2401 gcagtggaat cgctccttct acaatttgag cttgtctttc gttattcggt gttcgggcat
     2461 agtctggtcg cagggcaaaa aagatatcca acttctcctg agcctgagga tcaaagacta
     2521 atgctttccc taaaaattta gctagggttt gtttggttag gtcgtcctca gttggcccca
     2581 aaccgcctgt caaaatcacc agactgctac gttgactggc aatctcaagc aaagacaaga
     2641 gacgaacttc attgtctcct acagccgtct gaaaatatac atctacccca atctcagcta
     2701 gtttttccga caaaaactgg gcattggtgt tgacaatctg tcctgtcaaa atctctgttc
     2761 caacagcaat gatttctgct ttcatgtttc ctcctaccta tctattcgta tttttttgaa
     2821 aaaatcgcag gaattttcct acgattgatt ttttatttgt atcaaaagtt aattatcttc
     2881 atcaccaaca ggtgctctgc caaataaatc ttcaaataaa accgcattgg tttcaagctg
     2941 agtaacttct tcttgtccca aagaacgtcg gagtatattt tgcatttcca acatatgtgc
     3001 tcttgaaaca atctggtaag aaacaccttg aagtatctct ccttcaccct gcaactgctg
     3061 agtttcaatg gttttaaatg aatctttata gcctagcaag ttagggatac tttttgcaga
     3121 caaatcaata ttggtctgca tattgtcact caaagctttt agaatctctt gataatgacc
     3181 aacgctattt aaactgagag ctttttccat gactttttga ataacttcac gttgacgttt
     3241 ttgacgacca taatccccct caggatcttg gtaacgcatt cgtgcataga ctagggcttt
     3301 ttctccccca atatgttgct ccccaacacc gatagaaata gtattaaatt cttcttggtc
     3361 actgatagaa attgggaaac ctaggatatt attgactgta atacctccta ctgcatccac
     3421 tagtttttgc aaccctctca tattgaccat cacatagcga tcaatatgga tattcatcat
     3481 tttttgaatg gtttctatag caagctctgc tccaccatct gcatatgctg agttcagttt
     3541 cgcttcatga gcctgaccat tccctgattc aatgcgcgtc agaatatccc gctctaaact
     3601 catcattgtt gtttttttcg ttttaggatt cactgtcatc aagatcatgc tatcacttct
     3661 accgacccaa gtttcagttc gttcaacatt tccggtgtcc actcccatta acagaatggt
     3721 tagaggttca gtcgcttcaa taaccttggt ttcttcgccg atttttttat aggttttagc
     3781 taaggtttct gtcccttgtt gataaatagt ataagcaaaa acacctactc ctactacagt
     3841 tacagaaagt aaagctagca ccattccaat aattttttta accatatttc tactaaccta
     3901 tcagtttacc catcaagtaa acatcgataa atttcccttc ttctatatat gccccacgct
     3961 cttggctacc ttcaatgaca aagccatgct tttgataaag atggactgct gcttgattac
     4021 gagtttggac agtcagttgg agacgacgca gaatgccact tgcttgtgcc cactctatcg
     4081 cttcttctag caacaaactt cccaagccat tattccaata tctttttcca atcacaatga
     4141 agagatctcc aatatgacgg actctcttac gctgatcagc tgtaatattt acaataccag
     4201 caattttgcc atttaagaat gcaagtaagg ttatctgatt gtccgaacta gcttgcttgt
     4261 tgaggaatat ttccatctcc tcactagtca agagaatacc atctccgtct aggctggtaa
     4321 agtctgtctc caaactcaca cgatttaaaa aggccactaa ttcagctgca tctttgggct
     4381 ctgcttccct aatgagcaat tcatactcca tattgaagct cctctaacaa tttctcagca
     4441 cgcaaaccct ttgcctgaaa atttaaacgg cgtccatctg cttcttttag aatttccaat
     4501 tctaaataag catctggcaa ggcatctcct aagagatttc cccactcaat aacagtcacg
     4561 ccgccaccaa agataaactc atccaagtcg atagaatcag catctccttc aatacgataa
     4621 acatctaggt gataaagtgg aagtcgacct tcatactctc tcacgatagt ataggtggga
     4681 cttttaatca tttgagaaat ctgtaatcct tttgcaagtc ctttagtaaa ggtcgtttta
     4741 cctgcaccca gttctccagt taagattaaa acatcattct ttgctaatag atggcccaaa
     4801 cgctccccta aggcttgcaa ctcttcttca ttttttgtgt acatactctt attataccaa
     4861 aaacttttct tttgtgtcta ttttcctact aaacttatca tcataacatc cataaaaaac
     4921 aggctttctc taaaagaaaa tgagcgtaac aatgaccaat acaagatctc ggaaaatatg
     4981 accataaaag gaaacttcct tcttaaccga atttgggaca agataggctg caaaaaacaa
     5041 gcccagtcca atataaatca gaagtgagac aatggtcatt ggatttctta agaaaagaag
     5101 tgttgctaaa atagtcacca acactgtctt ttttctgtct agcatagcaa gaaaatcgcg
     5161 cacgtatttt ttcaagggta aaaaaatcag caaatctagc ccaaatagga aaaagaagga
     5221 tggcaataaa aagtcaacta attcttgctg cagcgtattt ttgatgaaca agttatctga
     5281 caaaacaaga acagctccta acaaattaat taagagtaac atactgtaaa aaagcttcac
     5341 cgacttctta ctggctagga cactatggac ttcttgctta cgggtataaa gataatttac
     5401 tccagcacag attcctgaaa cgaaaaccat gctcccgatg aaaaaagctg tactttgttt
     5461 aaaggacaag atgcattcct tccataggaa acagctactc aaactgattt gaattaaagc
     5521 taacaaaaat aagattctca ttgatttcat cttctctctc ccttcctacc aatcattata
     5581 ctaggagaaa agagagaact gtttctaatc ttctcaaatg tctctttaag acgctaaaca
     5641 aacactagag actaatactc aatgaaaatc aaagagcaaa ctaggtagct agccacaggt
     5701 tgctcaaaac actgttttga gattgcagat agagctgacg tgatttgaag agattttcga
     5761 agaatataaa tttgaaatca tgaaaatccg tcaaacgggt ggttgttttg tctcgcacct
     5821 cacggagcga gacggactca gagtcacata attataaggc tgatagtatt aatctaacta
     5881 tcagccttac aggttattta acgtttcaga aaaactataa tgtcaagatt aactaaacag
     5941 tatctaattc cttcaaataa ttttctatct tcatcagcat taaaggattg ttataaatct
     6001 tgcatagctc tcttgcttct atataataat ttttgacttg ttctctgtct agaaatttgg
     6061 ctccagcatt tcctacaaga ataagtagag gagccaattg gtagcttgtc tgtctttgtt
     6121 tacagagttc gatagtctca agagcttctt ggatggcttc attatatttt tcctttgata
     6181 ctaggtagtg agcgtaattg taacgaactc tgatgtagcc aaataaaaac tcttgatgct
     6241 caaaattttt tgtctgatat aactccatca aatgagagta gtttacctca tattcttgtt
     6301 cacgacccac taaggaatag aaattagata gagtattcaa cgcctttaaa taaatcaaag
     6361 tatttgagga gacttttaat aatatatttt ccaatgaaga aattgcttca cacttactgt
     6421 catattgaca gaagtcaata atagctttaa tccattcaag gtaagttcgg tcttctagtg
     6481 ttagaaaagt acttcgttca atctctattc tataaatata ttccaaattt tcataatttc
     6541 tatcatctaa taggcgagca gataattgct tgaaattaga gaggttagat ttaatttcaa
     6601 tttgttcatt aaaaaaataa tctaatggca cttcgagtcg ttgtgagagt ttgaacaaaa
     6661 ggtctgcgga gggaatgaaa taccctctct caattttact aatctggctc tattcacaaa
     6721 ttccttctgc aagagtttgt tgggagagtc tcaactcttt tcttttcaat ctgaatttct
     6781 ctgcgagtgt attcattaaa gataataaac cttcctattt gcttaatttc attataaaat
     6841 ttttagttca aaatagcaag ttaaaggaat aaataattct ttgcggtaat aaacaaaaaa
     6901 aagtcaaaaa ttacataaaa atgcttggct aaataaaata tatttgttaa aataaggata
     6961 atgaaaaaga aaagggtttc acgaatgaag aaaaatcgtg gaattcaaaa attagctata
     7021 ttagtattac taggtgtttt tatgtttagt aacacaattc cttaccaaca gtttattcag
     7081 aagaatagac aattggagat tcgagtccaa tcgcaaaaga agtccaatgg tcttgatgtt
     7141 gggaaggctg attgatttta tattacttta aaattcaact atttagagaa aggtattctg
     7201 atgagagctt gtaacaatac cagatagata taagaatgga gatgtttgat aaaatgcttt
     7261 catagctaac caactgttga aaattatgag ttacaaaatc taaagtattt aagattggtt
     7321 tataaaatta ggtctctgcc tgtagaaagg aacgtgcagt tagaaaggag gaaaaaatag
     7381 gatactataa ttcagactga gatttctaat taaaatatat agttgcattt cgctcatttt
     7441 cataatattt cattcagagg agtaataata tgttaaaatt tagaaaagta gttgcatcat
     7501 cccttgccgt tttggcattt agtttggctc ttcctgtttt ggcagtttct caccgtggtg
     7561 gcgagtggac ctatggaggc catcatgatc caaataattg gggagcattt tcgaattatt
     7621 atcatggttc acagtatcac tgggcctatg ttggaagtaa tggacgtaac aatcaaaaaa
     7681 cagtttatgc aggagcacgt agtgcggcct atgcgtttgt taatacaaat tttggggagc
     7741 aagttacatt tgatgcggga tggtaaagaa taattgaaga agattctttt atcaatagtt
     7801 cagtaagctt gttagtttat agagggcagg ggtatttctg ccctctgttt tagaataagg
     7861 aatgcactat gaaaaaatta tttatactca tatccaacct gcttgctagt ttgttctttg
     7921 tttgggtatt taccatttgg actgatacat atgtctccta ttattacccc aacgttgttg
     7981 tacatgattc ttcccctgaa acaacttttc agcatgttgc tacacgcttg gaaaaactag
     8041 cagaagaaac agatagcttt attgcgattc aacaccaaga tcctaactca gaaggtacta
     8101 cagttttttc ttatacgacc tttggggacg gaaagttgcc tgatgggctt caggaaaaaa
     8161 aactagaaga tgctcaaagt agtagtgttg aaacaaacta ttttgtattc gatggacacc
     8221 tagatattca cttgctaagg gaggagctaa gtcaacttgg cttgactaac atgaacctga
     8281 caattccatc taaactatct acgttaatgg ctatctttag taacggattt cagttaatca
     8341 gtctattgat tttcatctta acctttatag cactgacttt aattagtcaa attagccaat
     8401 tacggtcgtc gggcattcgc ctcatttcag gagagaaacg gtggtccatt ttccttagac
     8461 cagttggtga ggatttgaaa gggatagctg ttggtttcag tttagctggc gtgctcgcca
     8521 ttcttatgca aaaaattctg tcgcttccaa cgcaatccct aatgaccata ggagcaggct
     8581 tgctcagtta taatctcatc ttgttgtcga tctccctgtt tttcgctcaa ctcttcgcag
     8641 ttgggataaa aaagatacac ctgatgcaga ttataaaagg gcaagtgcct gtcagaggaa
     8701 tcattagttt gattttaatc ggtcaactat tagcgattat tattgtaacg ctgggaatag
     8761 ggagtagctt aaagtattcc caagcctggc aacagcatcg gattggacaa gaggcttgga
     8821 gtcaggaaag gcaactgatt accctatcaa tcagccgtga aggaacgagt cctggttttg
     8881 atgaacaagc tcaaaggaaa ctcagaactt ggtatcaatt gatggatctg gctgtttcag
     8941 aacaaaaggc tttcttatct agacaccagt taattgaccg tactttgcaa aatggcatgg
     9001 cttcctccaa aaacttgata acctctacag aatggcacga ttacaacccg aatggcaatg
     9061 tccttatcgt cacaccgcaa tacttggagc gtcaaaacat tcctgtagat acaactattg
     9121 agcaaaagat gaatcacctt gatgtagggg agtttgtctt attgctgcct gaacacctcc
     9181 gttcagagga agaacattat aaatctgttt ttgaagacga cttaaccagt cgcatgtcta
     9241 gtcaagatga acgacagcaa atgactgcta cggtaggtta tttagaatca ggtcaggatc
     9301 gttttgtgta taatacgacc cctatttctt accagcagtt tttgaaagat ccaatcatca
     9361 ttgttataac accccaatca actggtccac agtccatttt gttttggata gacgcagtac
     9421 agaactacgt tctctttaat caattgtctg atgcccagga gcttatccag agacaaggca
     9481 ttgaaaattg ggtctcagaa atgcaaacag gttaccacaa ctacatcaca ttattggata
     9541 atattcagag ggaacgttgg gtaatgctag caggagctgg gcttgggatt gcaacttcaa
     9601 tcttgttgtt taacactatg aataggctct actttgaaga atttagacgt gccattttta
     9661 tcaaacgcat tgcaggtctc aggttcttag aaatccatcg cacttatctc tttgctcaac
     9721 tgggtgtgtt tttactggga tttgttgcga gtgtatttct tcaggtagag ataggagttg
     9781 ctttcttagt cttgttactc tttactggtc tatctctttt acagttacat gtccaaatgc
     9841 agaaagaaaa caagatgtcc atgcttgttt tgaagggagg ttaatatgat tgaacttaaa
     9901 caggtgagta aatcttttgg agaacgagag ttattttcga atctttcaat gacatttgag
     9961 gctggaaaag tctatgcctt aattggttca agtggtagcg gaaaaacaac cttgatgaac
    10021 atgattggga aattagaacc ttatgatggg acgatttttt accgaggtaa agacttggcc
    10081 aattataaat cgagtgattt tttccgtcac gaattgggct acctcttcca gaactttggc
    10141 ttaattgaaa accaaagtat tgaagaaaac cttaagctag gtctcattgg tcaaaagttg
    10201 agtcggtcgg aacagcggtt gaggcagaag caggctttag aacaggtcgg cctgacttat
    10261 cttgacctag ataagcgcat ctttgagtta tcgggcggag aatcgcaacg ggttgccttg
    10321 gcaaaagtta tcttaaagaa tccacccttt attctggcag atgagccaac agcttcaata
    10381 gacccagcaa cttctcagtt gattatggag attctgctat ctcttcgaga tgataatagg
    10441 ctaatcatta tcgcaacaca taatccagca atttgggaga tggctgatga agtgttcacg
    10501 atggatcgtc tgaaataaaa atccttgttt ttaattgcac gatgagttac tgaaatatta
    10561 tcatgaatca ataattggag ttaatttaga attgtacttt attaatattg aggtaacttt
    10621 ttcttgataa aggaagaaat agtggagagg aagttagaat gaaaaaattc gacaattata
    10681 ttgttgagaa gccttgcgat tctaattcag ataaactgca aaaaatctta ataattgaaa
    10741 atttggtaga tgatattttg caatttcctc tcagaatcaa taatagtgta ggagagattt
    10801 tcctcctaca accgtttcaa aagaaaacta tctttattcc atgttatttt gaggaagata
    10861 ttgtgaaagt caaagatgat gataaagttg agtggaattt gttagaattt caaaaattta
    10921 gagcattttt ggcttagtaa tctgtgttga aggctcaaaa cctatggtaa aaaagtcgct
    10981 ttgaaaacgt attgcctcca aagatttagt taaataatga tttaacacaa aaagaaatta
    11041 ttgaagttct ggaaagatgt tgtttcagta ttgagaaaag gtgggaaaaa cttgcgattt
    11101 tcacagagaa aggaagaaaa agtatagaaa tatagtcaat tgaaacaaga acaggacaaa
    11161 agaacctttt gtgccatatt tttctccttt cgctttacaa ttggcttgaa cacctttatt
    11221 gtatcgcgtt tggagttttt ttggtataac cttcgacgcg cacccgcata gcgggtgttt
    11281 ttttgtctcg cacctaacgg agcgagacga actaatagtc acttaatcaa aaaacgcacc
    11341 atatcaaaaa ctaaaaagtt tgatatcatg cgtcatgtct taaactaatt gactatactt
    11401 tctattcaaa tgagctttta accaattgat tgagccaatc cactcttaaa accaaagagc
    11461 aatttctcgc ttagctgact cttctgaatc tgaaccatgt acaacatttt ggataacctc
    11521 attttctcca gcagcttttg caaaatcacc tcgaatagtg cctggtaaag cttcttctgg
    11581 acgagttgca cccatcatgg tccgccaagt ttcgattact ttgggaccag aaatgacacc
    11641 cacaagaact ggacctgaag tcatgaattc acgaatcggt gggtaaaaac tctgaccaac
    11701 caagtcctga tagtgctggt caatcaactc ttctgaaact tgtgaacgaa actccaattt
    11761 ttcgattgta aatccacgtt gttcgatgcg ctttaacact tcacccacta gccctctttt
    11821 tacaccatct ggtttgatga taaagaatgt ttgttccata cccgtctcct ttgtcagctt
    11881 ctttctttta ttttaccaca tttcgtggaa aaatggagaa agttttcaga atagagaatg
    11941 agagaacccg agggttctct cattctctat tattctactg tttcttccac agtttcaacg
    12001 gcagtatcca caactacttc tgttgtttct tcatttcctt cttcctctac tggaggatta
    12061 aggtattctt cttcgttgac agcatatggt tcaaggttac ggtaacgggc cataccagta
    12121 ccagctggga tgatcttacc gatgataaca ttttctttaa gtccaaggag atggtctttc
    12181 ttaccacgga tagctgcgtc agtaaggaca cgagttgttt cctggaagga agccgctgac
    12241 aagaaactgt ttgtttcaag tgaggctttg gtaattccca taaggactgg gcgacctgtc
    12301 gctggaactc cacctgcgat aaggacatct ttgttggcat ctgtaaagtc attgatatcc
    12361 atgagggtac ccatgagaag atctgtatca cctggatcca tgacacggac tttacggatc
    12421 atttgacgaa ccattacctc gatgtgtttg tcaccgattt ctaccccttg gctacggtaa
    12481 actttttgta cttcaccgag aaggtacgtt tcaactgaca agacatcacg aactgcaagg
    12541 agacgttttg gttggataga accttctgtc agagcagcac cacgcgctac ttggccccca
    12601 acttcgacac gcatacgagc tgtaaatgga acgacatatt caccttcgcc agtttcaccc
    12661 ttaacaaaga ctttcttggt acgagttgat gcatcttctt cgatagcagt aacttctcct
    12721 ttaacctctg tgataaccgc ttccccttta ggattgcggg cttcaaagat ttcttggaca
    12781 cgaggaagac cctgagtgat atcggtattt gaggcaaccc cacctgtgtg gaaggtacgc
    12841 attgtaagct gtgtaccagg ttccccgata gattgggcag caatggtacc aactgcttca
    12901 ccaacttcaa ccgcatcacc agtcgccaag ttgataccgt aacagtgacg gcagacaccg
    12961 tgacgagtgt tacatgtaaa tacagaacgg atagtcactt cttccacacc agcattgaca
    13021 atttcacgcg ccttgtcttc tgtaatcaat tcatttggac caataatcac tgcaccagtt
    13081 tctggatgtt taacagtttt cttagtgtaa cgaccgttga gacgctcttc gagagactcg
    13141 atcatctctt ttccttctgc gatagaacgg atcaagagac cacggtcagt tccacagtcg
    13201 tcctcacgga tgataacgtc ttgggcaacg tcgaccaaac gacgagtcaa gtaacctgag
    13261 tcggctgtct taagggccgt atcggtcata cctttacgag caccgtgagt tgagaagaac
    13321 atttccaata ccgacaaacc ttcgcggaag tttgaaagga ttggcaattc catgatacgt
    13381 ccattcggag cagccatcag accacgcata ccggcaagct gtgagaagtt tgagatgtta
    13441 ccacgggctc cagagtccat catcataacg attgggttct taggatcttg gttagcaatc
    13501 aagcgtttct caagtttttc acgggcagca cgccattcag ctgtaacagc attgtaacgc
    13561 tcgtcgtctg tgatcatacc acgacggaat tgtttggtga tttgctcgac acgtttgtgt
    13621 gattcttcaa tgatttcagc cttgtcatca acgactggga tatcggcaat acccactgtc
    13681 aatcctgcaa gagttgagtg gtggtaaccg agattcttca tgcggtcaag tagggcagaa
    13741 gtttctgtcg tacggaaacg tttgaagatt tcagcgatga tatttccgag gtttttcttc
    13801 ttgaacggag ggttgagctc aagattgctg atagcttcct tgatatctcc accaagtggc
    13861 aagaagtatt tagctggaac accttctgtc aagttggcat tgtttggttc ttgcaagtat
    13921 ggtagcccct ctggcatgat atcgttgaag agaattttac caactgttgt aagcaagacc
    13981 ttatgtcttt gctcttctgt ccaaggcttg ttgaggctgt ctgttgcgat accaacacgt
    14041 gagtggaggt gaacataacc attgcggtaa gccataaccg cttcgtcacg gtctttgaag
    14101 accattcctt caccttcgcg accagcttct tccatggtca agtagtagtt acccaaaacc
    14161 atgtcctgag atggagtaac taccggtttc ccatctttcg gattcaagat gtgctcagca
    14221 gctagcatga ggatacgagc ttctgcttgt gcttcttctg aaagtggtac gtggatggcc
    14281 atttggtccc cgtcaaagtc agcattgtag gcttcacaga caagtgggtg caagcgaaga
    14341 gccttaccat caatcaagac tggctcgaag gcttggatac ccaaacggtg aagggtcggt
    14401 gcgcggttca aaagcactgg gtgttcttta atcacttctt caaggatatc ccagatacgc
    14461 tcatctccgc gttccaccaa gcgtttagct gctttgacgt tttgcacgat atcacgggca
    14521 acgatttcac gcatgacaaa tggtttaaag agttcaatcg ccatttcacg tggcacacca
    14581 cattggtaca tcttaagagt tggaccaacg gcgataacgg aacgtcctga gaagtcaaca
    14641 cgtttaccga gcaagttttg acggaagcgt ccttgtttac ctttaagcat gtggctcaat
    14701 gatttcaatg gacggctacc tggtcctgtg attggacgac cacgacgacc attgtcaatc
    14761 aaagcgtcaa ctgcttcttg aagcatacgc ttctcatttt gaacgatgat acctggtgca
    14821 tttaactcaa gcaaacgagc caaacggttg ttacggttga taacacggcg gtaaaggtca
    14881 ttcaagtcag atgaggcaaa acggccacca tccaactgca acattggacg aagatctggt
    14941 gggataaccg gaagaatgtt aagaatcatc cattcaggtt tgtttccaga cttgtaaaag
    15001 gcatccaaaa catccaaacg acggatggct ttgacacgtt tttgtccagt agctgttttc
    15061 aattcttctt tgagttcagc aatttctttt tcaagatcta cttgcttcaa aaggtcttgg
    15121 atggcttccg cacccatctt ggcaacaaat gaaccataac catattcacg caagcgctct
    15181 cggtattcgc gctctgtcat gatagacttg tgctcaagtg gtgtatcctt aggatcaatc
    15241 accacataag ccgcaaagta gataacttcc tcgagggcac gagggctcat atcaagggtc
    15301 aagcccatac ggcttggaat ccccttgaag taccagatgt gagatacagg agctttcaat
    15361 tcgatatgtc ccatacgctc acgacgaact ttcgtacgcg ttacttcaac cccacagcgg
    15421 tcacaaacaa ttcctctgta acgaatgcgt ttgtacttac cacaagcaca ttcccagtct
    15481 tttgtaggac caaagatcac ttcatcaaag agtccttcac gttctggttt caaggtacga
    15541 taattgattg tttcaggttt tttgacttct ccataagacc atgaacggac tttacttgga
    15601 gaagctaggg tgatttgcat acttttaaaa cgatttacat caaccactat ttcttccctt
    15661 tctattctaa gtgaactgct tattcttgtt cagcagcttc ttctgttgct tccgcttttg
    15721 ttgctttctc agcttcttca gcttcaaagg ctgctttagc ctcttgagct gctttttcgc
    15781 gggctttttc aaggtcatct acgtggatga catcttcgtc cattccttca tccaagtcgc
    15841 gaagttccac ttcttggtca tcttcgtcta ggacacgcat gtcaagacca agagattgca
    15901 attctttgac aagaactcgg aaggattctg gaacacctgg ttttggaatt ggtttgcctt
    15961 ttgtaatagc ttcataggct ttcaaacgtc cgttgatatc gtccgacttg taagtcaaga
    16021 tttcttgaag gacatttgac gcaccgtagg cttcaagagc ccaaacctcc atctcaccga
    16081 aacgttgtcc accaaactga gctttacctc cgagtggttg ttgggtaaca gttgagtaag
    16141 gtccgactga acgcgcatgc aatttatcgt caaccatgtg gtggagtttg atcatgtaca
    16201 tgactccaac agaaacacgg ttatcaaatg gttcacctgt acgtccatcg taaaggattg
    16261 tcttggcatc gctatccata cctgcttctt taacagttga ccaaagatct tcagaacttg
    16321 ctccatcaaa gactggtgtc gcaatgtgaa taccaagagt acgagctgcc ataccaaggt
    16381 gaagctccat aacctgaccg atattcatac gtgatggcac cccaagtggg ttcaacatga
    16441 tgtcgactgg agttccgtct ggaaggtaag gcatgtcttc tacaggaacg atacgagaga
    16501 caaccccttt gtttccgtga cgtccggcca ttttatctcc gaccttaatc ttacgttttt
    16561 gagcgatgta aacacgaacc aacatgttaa cacctgattg caactcatct ccatttacac
    16621 gtgtaaagat cttaacatca cgaacgacac catcggcacc gtgtggtaca cgaagagaag
    16681 tatcacgcac ttcacgagac ttgtctccaa agatagcgtg caagagacgt tcttcagctg
    16741 aaagatcttt ctcaccctta ggtgttactt tacctacaag aatatcacct tctttaacct
    16801 cagcaccaat acggataatc cccatttcgt caaggtcttt gagggcatct tcaccaacgt
    16861 ttggaatttc gcgagtgatt tcttcaggcc caagctttgt atcgcgcgtt tctgattcgt
    16921 attcttcaag gtgaacagat gtgtagacat cgtccttcac caagcgttcg ctcatgataa
    16981 cggcatcctc gaagttgtaa ccttcccaag tcatgtaggc aacgattggg ttttgtccaa
    17041 gcgccatttc tccattttcc atagaaggtc cgtcagcgat gaaatcgcct ttttcaacga
    17101 catcaccaac ttttacgaga gtgcgttggt tgtaagcagt acctgagttt gaacgacgga
    17161 atttttggat gtggtaaaca tccaatgaac catcttcacg acgaacttct accttgtcag
    17221 catctgcgta agtaacttta ccatcatact gagcaatcac agccgcacca gaatcgtggg
    17281 ctgcttggta ttccatacca gtaccaacgt aaggtgcctg aggattaatc aatggcacag
    17341 cctgacgttg catattggct cccatgaggg cacggttgga gtcatcgttt tccaagaaag
    17401 gaatacatgc tgtcgcaacg gcaactacct gttttggtga aacgtccatg tagtcaacaa
    17461 tattagctgg atactcttgg ttgacccctt ggtgacgtcc catgacaatc ttctcagcaa
    17521 aggttccatc ttcattcaga ctagagttag cctgagctac agtatattca tcttcttcat
    17581 cagctgtcaa ccaaacaatt tcgttcgtga caacacctgt ttcacggtca accttacggt
    17641 atggtgtttg aacaaaacca tatttgttca agtgtccgta agatgacaag ttattgatca
    17701 aaccgatgtt aggtccttca ggtgtctcga ttggacacat acgaccatag tgagtgtagt
    17761 gcacgtcacg tacttcatat ccagcacggt cacgagtcaa accaccaggt cctaaggctg
    17821 acaaacggcg tttgtgagac aactcagaaa gcgggttgtg ttggtccatg aactgtgaca
    17881 actgtgatga accaaagaat tctttaactg cagctgttac aggacggata ttgataattt
    17941 gttgtggtgt caagacttca ttgtcctgaa cagacatacg ttcacggaca ttacgttcca
    18001 tacgagaaag tcccaaacgt acttggttgg caagcaattc accaaccgca cggatacgac
    18061 gatttccaag gtggtcgata tcatctacac ggccaagtcc ttcagccaag ttgaggaagt
    18121 agctcatctc agcaaggata tctgcaggag tcaccgtacg aaccttgtca tctgggttag
    18181 cattaccaat gatcgttacg acgcgatctg gatcagttgg agcaacaacc ttgaattttt
    18241 gaagaacaac aggctcagtc acaacggctg catcgtttgg gatgtagaca atcttgttca
    18301 agtcgccatc caaatggctt tcaatgcttt caatcacgct acgagtcata atcgtaccag
    18361 cttctaccaa gatttctcca gtttcagggt ctaccaatgg ctctgcaatg gtttggttga
    18421 gcaaacgtgt tttaacattg agttttttat tgattttgta acgaccaact gctgccaagt
    18481 catagcgacg tgggtcaaag aagcgagcca caagcaagct acgtgagctt tcagctgtct
    18541 taggctcacc tggacgaagg cgttcgtaaa tttctttcaa ggcttcgtct gtacgagagt
    18601 ccattggatt cttgtggata tctttttcaa cagtgttgcg aaccaattcg ctgtcaccaa
    18661 agatatcaaa gatttcatca tcacctgaga aaccaagagc acgaaccaag gttgtaaatg
    18721 gaatcttacg agtacggtcg atacgagtgt aggtgatatc ttttgagtcg ctttcaagtt
    18781 ccaaccaagc tccacggtta gggataacag ttgaaccata gcccacctta ccatttttgt
    18841 ctactttgtc gttaaagtaa acacctggtg agcggaccaa ctgagaaacg ataatacgtt
    18901 caccaccatt gatgatgaaa gtacccattt ctgtcatgat tgggaaatca ccaaagaaaa
    18961 cttcttgggt cttgatttcg cctgtttctt tattgatcaa gcggaaggtt acaaaaattg
    19021 gtgctgagta gctagcatcg tggatacgag cttcttctag cgtgtatttt ggttccttga
    19081 tttcatatcc aacaaattcc aactccattg tgtctgtgaa gtttgaaatt ggcaatacat
    19141 cttcaaacac ttccttaaga ccgtggtcta ggaaagcttt gaatgagtca gtttgaattt
    19201 caatcaaatt tggtaagtca agaacttctt tgattcttga aaaactacga cgggtacgat
    19261 gtttcccgta ttgaacgtca tgtcctgcca agatgattct cctttgtaaa taagttccaa
    19321 gccttgtcaa tcaggctttt ctaatcgcca tatggttgta aaccccttat caccgtgtcc
    19381 tcttgacgaa ttttcagaat ctttaagcct ctgttacaaa tgctcaaaat cttgaaaaaa
    19441 agcacaaaaa gagcagctaa atctgacttt ttcagaagat ttaactgctg tgagccttgt
    19501 ctggacaata tttcagacaa aacctacgac aaatgattac ccatattata ccctatttag
    19561 ctagattttt caaggggatt cagtaggttt ttggtaattt ttttcccata gaaaacttgg
    19621 catcacattc gaatcacgct atggtacaaa aaactgaaaa aactattgac tgaaaatcat
    19681 tttcaaggta taataataaa cgttaaggcg gtatagccaa gtggtaaggc acggctctgc
    19741 aaaagcttga tcgtcggttc aaatccgtct accgccttct ataacttgat ttatcaggtt
    19801 tcaaatgaac agaaagccca atttgaaggg ctttttttat tttccctcga ataaatacgt
    19861 ataactttaa aaacttttgg agcgagtttg tggcagagtt ctttccatgg cataattccc
    19921 ttttgaaatc aattgaaaaa agcttcgtca cgcctggtga caaaagcctc tagtttattc
    19981 tgtttcttct tctatttcga cttctgtgat ttggactttt accttggtaa cacgtccatt
    20041 cttcacttta tcattggtta agataaactg tttgttttgg ctgaccaatt catagctgag
    20101 tttctcagtc gttggaatgg ttcccactcc tgtcaaataa taaccagcga tagtatcaac
    20161 gtcatcactt tccagttcaa cattaaagta attattgaaa tcattgaggg tcatagttcc
    20221 ttgaacaatg taggtatcct cgccaatctg atgaacatct attgctgctt tgtccgtttc
    20281 atcatcaatt tcaccaacaa tttcctctaa gaggtcttcc aaagtcacca aaccagccat
    20341 accaccgtat tcatccagca agattgccat ttgtctttgg gtatttcgca gttcttttag
    20401 caagtcatcc acaaaaatag tttcaggtac aaaaagtgga tcttgtaaaa ttctcttcca
    20461 aacaatattg tcaaaaccgt ccacaaagcc tgccttaagg agactcttgg tgtgaatgat
    20521 tccaattaca ttgtccttat ccccatcata aaccgggata cgagaataat tttgttttaa
    20581 aatactttgg ataatggctt gactatcatc ctgaatatcc accataaagg catccgttcg
    20641 aggaaccata acctctcgtg ccatcagttc atcgagcgaa aagacacctt gtaacatctc
    20701 aatctcatca gcatccaatg tttcttcact atttgtcagc atataggcaa tttcatcacg
    20761 ggtcatcttt tcatccgcat catcgaatga cataggagtc aaatggctca agaaattggt
    20821 cgaagcagct aaaagccaaa caaaaggact gactagtttt ccgatcccaa tgataaccgg
    20881 cgctgtacga attgccaagg catcctttag attaagagcg attctcttag gatataattc
    20941 cccaaaaacg atggaaatat aggtcaaaaa tgccaaggat agaaaagttg ccacggcttg
    21001 tgctgtttcg ccattcccaa gccaagaggc aatcacacgt cctagagtat cagttaaact
    21061 cgcccctgat aagattgtaa tcagggtgat tcctacctga atggttgata aaaagtggtt
    21121 aggattttct agtaccttca gcaggcggat gtagcgtctg tctccttctt ccgccttttg
    21181 ttcaactcgg gcacgattaa gagaaaccat ggccatttct gtggctgaga aaaaggcatt
    21241 taataccgtc aagataaaca ataaaacaaa ttgtagcaac aaattctgac tacttgggtc
    21301 ttccatagtt cttctcctaa aatagtatct tatcctttat tatatcacaa aatttaatcc
    21361 aatacatatt atttttttct tagcgtaact tccatctctc tcccaaaact ggaagttagt
    21421 ctaagacgga tttccactga tttcacgcgt ttttctcata ctaaaagcta ggttgtggga
    21481 aactggaagt tagttttaga agttactatt ttttcttagt acctgttcta gccctgctta
    21541 aactagtaaa aagaactcct acatccataa gtgacatagg agtttaggct tatcttttac
    21601 tgagttacag ttacttctcc agttcggtaa tccagttgaa gtcccttttg aacattggga
    21661 actagaacat tgaattccaa ttctccatcc gaagacttgg cttcaatctg tgaagctgag
    21721 ggaactaaat cctcgtttga agcgtagtaa agggttacac ggtaacggac acgcttgttt
    21781 tggtccaagg ctttacgcac cttgctttca tagtagtttt gaccagtcga atactcggct
    21841 tgtgcctgat ttgcccaggc tgtctgaaca gcaatgtttt taggattgct tgttgaggca
    21901 tcaaaaccat ccaaaccacc gattaaggca tagcctaaca aatgacctct atcgactgca
    21961 tgggtataag agccctttag attcttgacc tgatgccaac ctggaggagt ccaagaagtt
    22021 gaaccattcc cagtttcttt acgattcttg tactgacgag tggccttaga caagagggca
    22081 ttagctacgg ttggaacagt ttccttaccc actgtctttg ttttattgtc agcgtagggc
    22141 ttacttgaaa ccttggcatc tagatttgtt ttattaccat tgacgataaa agcacctgag
    22201 ccattccact ccagactccc ctttatttga ctcttgactg cgtctgttaa gacactctct
    22261 gccaatgctt gactaggagc ttcaggcgct tgttttttct gactaagctt ggttttagga
    22321 ctattagctg tcgactgcat ctgcttgata taatagctcc ctgtagacaa aagcaataac
    22381 actagcagtc cgattagtgt ctgtcttgtt tttttgttca tatttctcct tatctttaga
    22441 aaaaggctgg ttctccagcc taatttcctg taaatttatg aatcaattcc tgccattttg
    22501 ctggagacag gatagcccat gaatcttgac ccttgcccaa gattccataa cctaccatta
    22561 aaccgattcc tagagccaga gtacctaaaa tcagtactat gatgactaaa agtaaacgct
    22621 tgactacgta gcttgatttc ttattcatct tcatcacttg cctcaatccg ctgaatctta
    22681 gcacctagct gcgccaactt ctcatggaaa ccgtagtaac ctctatccaa gtgaaccaat
    22741 ttaccgacca cagtttctcc ctgtgctacc aaacctgtca aaatcaaagc tgcactggca
    22801 cgaaggtcag ttgaaagaac ttctgctccc tgcaaaggct gtccaccaac aatacgagct
    22861 gtatcacgga taatctcaga atgcaagccc atgcggcgca tctcttctag gtgttggaaa
    22921 cgattttcaa aaactgtctc caccatggtt gattcgcctt ttgcaactgt catcaaggct
    22981 gtaaattgag cctgcatatc tgttggaaat cctgggtggg gcaaggtttt cacatgaaca
    23041 gcttttagat tttccagttg agaacgaaca cgaattcctt cgtcttcttc aattacttca
    23101 acacccattt caagtaactt ggcaatcaag ggacggttgt gctcccagac agcgtctcga
    23161 atcaagacat caccaccagt catggcagca gctaccataa aggttcctgc ttcgatacgg
    23221 tcctggacta cattgtgagt cgtaccatga agtttctcaa caccagtaat ggttatagtc
    23281 tctgtaccag cacctttgac cttggctccc atttcattaa ggagaatggc taagtcaaca
    23341 atctcaggct cacgcgcagc attctcaatc actgtcaccc catcagccag agtcgctgcc
    23401 atcatcaagt tctgcgttgc accaacactt ggaaagtcca tatagatatg agcaccatgc
    23461 aagcgttctg cctttgcttc gatgtaacca gctgtctgac taatcttaac ccccatagct
    23521 tccagacctt tcaaatgaag atcaatagga cggctaccaa tcgtacaacc acctggcatg
    23581 gataccttgg catgacccac acgggcaagg attggcccta atacaacgat ggaggcgcgc
    23641 atcttactga catacttgta aggggcttcc tcagtgatgt cgccagtagc atccaccttg
    23701 acaagatgag cttcctcatc aaagtcaacc ttggcattca aaccaccaac tacctgattc
    23761 ataataaaga catccgacaa aatcggaaca ttctgcaaga cggtctttcc ttcacttgct
    23821 agaatagtcg ctgccaacaa gggtaagact gcattttttg ctccctcgat cgtcacgctt
    23881 cctaccagac gattatcgcc accttgaacc acaattttat ccatactcgt ttcctttact
    23941 cttgatttta taataatcct ctaagcgctt cttgccacaa atgatacagg ctaataaaga
    24001 aagaactcag gatgtagcct atgacaatgc taaaaaaggc tactaataca cgaacttttc
    24061 ttgtattctc agctgtcact tttaaaacct tttcccatct aacaagatcc tttaaaaggt
    24121 aaaaactcac ataaataaag agcatatgac tacttagagt gaataataat tgaaccattt
    24181 gactattata ccatcttctc tgtttgtgcg ctagtttgga aacttcactc aaaaattagg
    24241 gattgttttt caagtaatca atcgcatctt gtagggtttt aacgggcacg attttcatat
    24301 ccgtcttgat tgttttagcc gcttctaggg ctgtttggta gttgtttttc gcgtccggat
    24361 gcgccttttg ttcttcttcg ctaacagggt tatcaggagc aaagaaaata gcagcacctg
    24421 ccctagccga agctacaacc ttcttatcaa tacctccaat gtctcccaca ttaccatcgc
    24481 ggtcaatggt acctgtaccg gcaacaatac gaccattacg aagatctggg tgagctattt
    24541 gagtatagat agctagacta aacatgagac cagcacttgg gccgccaata ccagctgttg
    24601 aaaagctaat tgggacattg ctgattacct ctgtacgatc aatcaagccg attccaatcc
    24661 cattttttcc attttccaag gtgataatct tcccttctgc agacttggtt tgcccatcct
    24721 cttcataggt gaccttgacg gaatccccta atttttgaga actgacgtaa tcaatcaagt
    24781 ctttggaact atcaaaggtc tgatcattga ctgctgtgac tgtatcagag atattgagaa
    24841 tccctttaaa ggttgaatta tccgtcacat tcaaaacata aactccaaag tacttgagtt
    24901 cgatatcctt accagctgtt tttagtcctt gatacttggc catattttgc gatgtttgca
    24961 tgtagaattg attgattcgc ataaattcaa catcggaaga accacctgta gtctcctgag
    25021 cactacgaat atctgtaaaa ggtgtcaacc aagcataaat catatgagct aaagtagcat
    25081 gttgaacacc aaccgtaacg aattgatagg caccagcttc cttatcttct gtgtcattta
    25141 ctttaaggac ttggcgaata tcttccgaac cacctggaac ctctatataa taaggcaagg
    25201 gcactacaaa tgccaagaaa gtcacaatca aggccgcaat gacgtataag ggccatctaa
    25261 tctttttttt catttcttat ttcctccaaa atactctcgg gaacatagca ggcaatatcc
    25321 tgaccaaact tcaaaagctc tctaacgcct gatgaactga tatagagatg ttcaggtcga
    25381 ctatgtaaat aaatagtctc tatatcagaa gacagctgat gattgtagta atcaaaactg
    25441 gcttcatatt gcaaatccga cgcattcctc aaaccacgca ctagacaagt agcacccaat
    25501 ctttttgcaa catcgaccac caattcatca tgagaagcca cgacttcaac attttccaaa
    25561 tgtcccaaag ccttttctag cccccgttta cgattttcaa gagggagaaa tccttgtttg
    25621 tggggattaa aaaaaatacc cacacaaagc ttatcaaaaa gtctgctcgc ccgttcaatg
    25681 atatccagat gcccatttgt catcggatca aatgagcctg tgaataagcc aatcttatct
    25741 gacatagact gtcaccttac taattccata aatcttttcc ttccagatac ccagacaggc
    25801 aatttcttct ggaagttcaa cggtcttatc cgtctcgcac acaaccataa catcttcaga
    25861 aaaaagctct ctctcagcca ttttttcaat atctgctacg atttgttcct tggcataggg
    25921 agggtctaag aaaacgaggt caaattcccc agatacctgt tccaatgccc tttctgcatc
    25981 cattttgagg agttgaaatt ttccaacttc cttggtcatc tggatatttt cagccacgat
    26041 ggtctgagcc ttacggtctc gctccaccaa aacagcactg gacatgccac gcgatactgc
    26101 ttcgatagat aaaccaccac tacctgcata aaggtccaag actcgtccca cttcaaagta
    26161 gggaccaatc atgttaaaaa tggctcccct aaccttatcc gaagtaggtc ttgttgtctt
    26221 gccttctagt gtcttgaggg gacgtccccc atagattcct gatacgattt tcatactgtt
    26281 tattatacca aattatagac aaaaagagaa agaaaaccga accttgcggt tcgattctct
    26341 acaaaatatt ttcgtaagta tcgcggactt cttgaggcca aacacttgtt tgcacttctc
    26401 cgatgtgtct cttgcgaagt aggaacatgg ccatacgaga ttgtccaatt cctccaccga
    26461 ttgtcaatgg gaataggcca ttcaacaaag acttgtgcca ttccaattct aagcggtctt
    26521 catcacctgt aatttccacc tgacgtctaa gagtttcttc atctacacga attcccatag
    26581 aagacaactc aaaggctcca cctaaagact cattccagac aagaatatca ccatttagac
    26641 ccttgtagcc attctcagac tcgcttgtcc agtcatcata gtctggtgca cgtccatcgt
    26701 gcggtttacc atctggcaac tcgccaccga taccaatcaa aaagacggct ccaaattctt
    26761 tacaaatcgc attttcacgt tctttaggtg tcaagtctgg gtagcgttct accaattctt
    26821 ctgtatggat aaaggtgatt tgttttggca agatagactc gatgtcatag cgggcttcaa
    26881 cagctagctc agtcaggcga atagccttat aaatcttctc aactgtttct tttagataaa
    26941 cgatgttacg cttaccattt gggataacct tctcccagtc ccactggtca acataaacag
    27001 agtgggttgc atccaaggaa tcctcatctg gacgaagggc tttcatgtgg acaaagagac
    27061 cctctccttc accaaagcca aaacgagcca aggtgtggcg tttccattta gcaagtgagt
    27121 gcaccacttc ataagtagca tcagggattt ggagaacctt gaccgatact ggattttcca
    27181 caccagacag gttgtcctgc attccgtcac cgaccttact caagatagga ccttgaactt
    27241 cgacaacttc tagcttatct ttcaaatact gggtaaaagt gtttttgaca aaggaaattt
    27301 cttcttgttg atggataaaa cttttcttca tagacaactc ctcaaaaatt taataaacgt
    27361 attatacacc tatttccaag aaaagaaaag agaaaatttt aaaaaaatca gtgtcactca
    27421 aaacactgat ttcatagacc ttttagtcat tgcgaccaaa gatacgtaga atacttagga
    27481 aaagattgat aaaatcaaga tagatgctga gagccattga caccacccag cctgtcgcta
    27541 cacgaccttg tgattgttca taggcgaggc gaatcttttg gttatcccaa gcaatcaacc
    27601 ctgaaaaaac caaaaccatg gctacgctaa tcatataatc aaagaagcca ctagccaaga
    27661 aaatattgac taccatagca atcagtaaac caatgagagc tgccatcatt gctcgaccaa
    27721 tcccactcaa gtctttcttg gtaaaaatac caactgccgc catgacaaag aagagaaggg
    27781 cgctcgatac aaaggcagat aaaactgtac ccggagtata gaaagccacc acaaaactaa
    27841 gggtaaagcc gtttaaaacg gagtaaagta aaaatactgg aagagcagct ggactatttc
    27901 ttgaagccat gctactggca acgaaaacca aagccaactc cgcaaaagta gcaatggtca
    27961 accagagacg cccctgcatc aacaagtaaa ccaactgaga ctgaaagacc gtcaacataa
    28021 ggcctgatac caaagcagat agtccgattc ccagaccaac aaaggcataa accttagcgt
    28081 aaaattgatt gagacctgca cggtcatgta taatagtgtg attcatcctt ttctcctttt
    28141 ctgtgaacat ctttccttga ttataacaaa aaaagttaaa attagcttaa atggaagatt
    28201 aaaataccgg ctgcaactgc aacattcaaa ctctcggcct gccccttcat gctaatatgg
    28261 accaactggt ctgcactttc agccataagg ggactaattc cttgaccctc atttcccata
    28321 actagtacaa aattttctat agaaggcagt tctctgtaat caacagaatc tttagatagg
    28381 gttgttgcta gcactgggat agctaccttt ttagtttcgt caagaagcgc ttgactagtc
    28441 atccggtaaa tgggcagatg gaaatgacta ccttgcatgg aacgtagggt tttgagactg
    28501 tagatgtctg ccgacttatc tgaaacaatc actcctgtaa aacctgctgc atccgcagtt
    28561 cgaatgatag ttcctacatt accaggatct tgcacatctt ccaaaaacaa gaacttgccc
    28621 tgactcaaat cagcttgtcc tacttcttct ttttgaacca cggcaacaat tccctgtgga
    28681 gtctgagaat ccgccaaatc tagcaaaata tcctctgaaa tccagacagt ttgcggaaaa
    28741 gcagctaact gatttcgata attttctagg gcaaagattt tctcaatcgt cactccagct
    28801 tggacagctt cttcaaacaa gtgccagcct tcaatcaaat aggcagactt gcggtatttt
    28861 ttttggtgta atttcttggc attttttacc acagaattgg cttttgaggt tataatagtc
    28921 atagaaatat tataacacaa tcaaaggggt ttggtatgca aaaggttaga atgattgccc
    28981 aaggtagggt gcagggagtc ggctttcgtt ggggtgttta tagcctggcc cttgaaatcg
    29041 gtggcatcac aggtcgggta tggaataacg acgatggcac agtggaaatc ttagcccaag
    29101 cagactcatc tgctatcatg gcaaaattta tccaagaaat ccgaaaagga ccgacacctt
    29161 tttcaaaagt aagctactta gatgtcaaac taagcaactt tcctccctac tctgacttta
    29221 aaatcgcaaa ttaggtctcc agaactattg tatattttgt aaaaaaacag tagaatagaa
    29281 aggtataatt tttaaagaag gaataaaaac agtgaaatct attaaacgtt ttgcattctc
    29341 ggctatggga gtggctatgt tgcttgtctt gactggctgt gtcaatgtcg ataaaaccac
    29401 aggtcagcca acaggattta tttggaatac gatcggagcg cctatggctg aagccatcaa
    29461 gtacttcgct actgataaag gtctaggctt tggtgtcgct atcattatcg taaccattat
    29521 cgtacgcttg attatcttac cacttggtat ctaccaatca tggaaggcaa cgcttcactc
    29581 tgaaaagatg aacgctctca agcatgtcct tgagccacac caaacacgtc tcaaagaagc
    29641 aactactcaa gaagaaaaac tcgaagccca acaagccctc tttgccgctc aaaaagagca
    29701 cggcatcagc atgtttggtg gtgtaggatg tttccctatc ctccttcaaa tgcctttctt
    29761 ctctgctatc tactttgctg cccaacatac tgaaggggtt gctcaagcaa gctacctagg
    29821 cattcctcta ggttctccaa gtatgatttt ggttgcctgt gctggtgtcc tttactatct
    29881 tcaatcgctc ctttcacttc acggagtaga agatgaaatg caaagagaac aaatcaagaa
    29941 aatgatttac atgagcccac tcatgatcgt cgtcttctcc ctcttctcac cagctagtgt
    30001 cacactttac tgggttgtcg gtggtttcat gatgattctc caacagttta tcgtcaacta
    30061 tatcgttcgt ccaaaacttc gcaaaaaagt ccgtgaagaa ctagccaaga acccaccaaa
    30121 agcaagtgct ttctctaaac caagtggacg aaaagacgtt acccctgaac aaccaactgc
    30181 tatcacaagc aagaaaaaac acaaaaatcg caacgctgga aaacaacgtt cgagataaga
    30241 agaaaaaggc ttagctgatt tgctaagtct ttttgcaaat caaaagcccg atgtttccat
    30301 caggcttctt ttctatccat gtacacgttt catataatct tgataacttt cggtatccat
    30361 gagtttttta gcgttcttga cgcgatctgc tgttggtggt ttgactcctt cgagggaata
    30421 tggaattcca agttcacgcc acttgaactc acccatggtg tgataaggta gaatttcaaa
    30481 cttatcaaca tttttgaggg tcttgacgaa cttaccaagt tcaatcaagt catcatctct
    30541 gtctgtcaat cctggaacta gcacgtggcg aatccagaca ggttttccaa tatctgatag
    30601 atactgggca caagccaaga tatttttatt agtttggcta gtgacaatct tgtgctgttc
    30661 ttcgttgatt tccttgatat ccaaaagaac caagtcagtg acagccatga gtttgtcaaa
    30721 cttctcaagg taacgtggtt tattacggaa aggaagagca caggtatcca aggtacagtg
    30781 gattccttgt tccttagcct tggtgaagag agcaatcagg aaatcaatct gcaagagagc
    30841 ttctcctcca ctgactgtaa tcccaccctt atttccccag aaaccacggt agcgcaaggc
    30901 ctctgtcaag acatcatcta ccgtccgttc acgtgactta ttggactcca tagcccaagt
    30961 gtctgggttg tggcaatact ggcaacgcat gtgacagccc tgcaaaaaga caataaagcg
    31021 aataccaggc ccatctactg acccaaagct ttctgtcgaa tgcaccattc ctgtcacttg
    31081 tccataatca attgtttctt cagacatatc gttaccttcc ttgaaaacgt tttatagttt
    31141 tattatatca cgacttgaag gaaaaacaag atttttgcct attttttaga aagcaatctg
    31201 tttttcaatt tcattttcaa tctattatca gattattctt caaaatcgaa gccatataag
    31261 gttgcaaaat agtcctcagg gcgctctgca cggcggattt gacgggcttt accttcttcg
    31321 gtatagagga tttccgcaga acgtaatttg gcattatact ggtagcccat tgaaaatccg
    31381 tgggcacctg tatcatgaat taccagcaaa tcaccgattt ctgtatgagg cagttcgcga
    31441 ttgactgcaa atttatcatt gttttcacag agtgaaccaa ccacatctac cgcttcagct
    31501 ggtccatctg gatgggtcac gttgctaata tgatggtaag ctccgtacat agctggacgc
    31561 atgaggttga ctgctgaggc atccacacct agataggtac ggtaggtttc cttcttatga
    31621 gtcactcttg tgactagagc accgtgaggt gccagcataa aacgacccaa ttcggtgaaa
    31681 atcttgacct gaccaagacc tgctgacgta agaacttctt catacacctt acgaactccc
    31741 tcaccaatca aggcgatatc gttcggctcc tggtctggac gataattaac accaataccg
    31801 ccagaaagat tgataaagtc tagcgaaatg cccaactttt ccttgatttc aacagccagt
    31861 tcaaagagct gacgagccaa ctctggataa tagagatggg tcacggtatt ggacgctagg
    31921 aaggagtgaa tcccaaaagt cttggctcct ttttccttca agatagcaaa ggcttcaaag
    31981 agctggtcct tggtcatgcc aaacttagcc tccccaggat tgtccataat gtctgtcccc
    32041 agttcaaaaa cgcctccagg attataacga caagagatga tttctggaat gcctgctact
    32101 ctctccagat gttcaatatc ttcaaaggca tccaagttaa tggtcgcacc caattcacgt
    32161 gcataggcgt attccttgtc tggcgtgttg ttggaagaga acataatctc agaacccaga
    32221 aagtccagtt tatggctcat caaaagctct acataactag agcagtccac accacaacct
    32281 tcttcttgga gaattttcaa aatagctgga gttggagtag ccttaactgc aaaatattcc
    32341 ttaaagccct tgttccacga aaaagcttgg ttgacggctc ttgccttctc acgaatcccc
    32401 ttctcatcat acaagtgaaa gggagtcggg aactcggcaa caatcgcttc taactcttct
    32461 ctattgataa atggtgtttt cataagcttc cttctattct gtttgcaaag aaaggctggg
    32521 acaatcgttc caacctttag ttctatctct tatttatctt cgtcaaagat attgccaacc
    32581 tcaacatcga tggcttggtt cttgacatca atattggtta ccttcaagag tgacttgtag
    32641 tcaaactgct tttcacgttc ttcttgggca ttgtccgcaa agaccgctac acctgccagt
    32701 tctgagtcga actcgtgcaa gagactaatc ataccattga ccgttccgcc acctttcaag
    32761 aagtcatcca caatcaagac acggctgcct gccttaagac tacgttttga aaggaacatt
    32821 ttctcgatac ggtcaccact tgaacctgaa acatagttga cgctaacagt tgaaccttcg
    32881 gtaattttca ggtcacggcg cacaatgaca aaagagacat tgaggacatt ggcaactgca
    32941 tttgcaagtg gcacaccctt agttgctacg gtcataaccg cgtcaatttt ttggtccata
    33001 aagcttttgg caataatacg accaatattt ttcaagatgg ctggtgtgct aagcaaatca
    33061 gacagataga tataaccacc tggcaagata cggtcacttt ctgacaactt ggtacgcaag
    33121 tcttcaacca tttccttagc atcctgactc gaaatagacg gtgtgaagat gacacctccg
    33181 ccagccccag tcactgtctg gatatgaccg atttcaattt cctcaaaggc gcgtttgata
    33241 atgacgatat cttctgagat ggatgattta gcagactcat acttttcagc aaaagtattg
    33301 agactagtta gtttataagg attattaatc aaatagttgg aaatgacaac catccgatca
    33361 cttcttctta atttcatttc tatttcctat tccattttta ttcaaaaaat caaaaagcaa
    33421 actagaaagc tggtcgctgg tggttcaaaa cactgttttg agattgtcaa tagaactgac
    33481 aaaccctgta atatacctgc atatatacat acgacaaggc gatactaccc tagtttgaag
    33541 agattttcga agagtattca tttttgtctt ttacttatta taccatattc acataaaaaa
    33601 acgaacattc ttatcctaaa aaatgctcat ttttcttaaa ttatcaatct aaatctggtt
    33661 tatagaagga acgattatcc atagcgaaga ttttattggt catctctcct ttatccacca
    33721 aagccagagc tgttgacatc atcatcatgc ttgcatccag attgtcaatc atatggataa
    33781 tctctgcctc cataatacgt ggacggactg gacttccata ttcaagcaag ccgtggtgac
    33841 tgaggatgac atgacgaagc aaaacgactt cttccttggt atcatcgatg ccgagttcca
    33901 taactgtctt ggtaatttcg ctatcaatga gagcgatatg tccaagaaga ttacctcgca
    33961 ctgtgtactc tgtctggtct ggccccgtca actcgataac cttagctaag tcatgcagca
    34021 taatccccgc atagagcagg ctcttattga gctgaggata aacttcgcta atagcgtctg
    34081 ccaaacgtac catggtcgcc gtatgataag ccaaccccgt ttcaaaggca tggtggttgg
    34141 tcttggcagc tggataggag tagaattcct tatcatactt ggtgtagaga tttcggacaa
    34201 tccgttgcca gacaggattt tcaattttga aaatcatttg cgacatgtag tcacgaattt
    34261 ccttgacatc aactggtgac ttgaccttga aatcggctgg gtcattgggt tcaccagctt
    34321 gaggcaggcg gagagtaatt tgattgactt gaggggtatt gttataaact tctcggcgtc
    34381 ctttcatgtg gacaacctta cctgcggtaa aggcctcaat gttatgaggt tgggcatccc
    34441 agagcttccc atcaatctcg ccactatcat cttggaaggt aaaggctagg tagtttttcc
    34501 cagctcgagt ttgcctcagg tcagctgatt tgattaggta aaagccttca aatagctcat
    34561 cttttttcat gtgactaatc ttcatattct tcctcatttt cttgaaaatg gagtagatca
    34621 agcgcaggct caccttctga caactcaatg tgacggagcg tccgctcgat agctatggta
    34681 cgacggttta ataattcatc aatattgcca gaggcatgtt ggagatgttt ttgtgccttg
    34741 accagaatac caccaaactt gccaaactcg gtcttgacac tggcaagagt cttgctgata
    34801 tggtcggcac tcttttggat attaagggtc ttgaaaccaa ctgatagaga gttaagaagg
    34861 gctgataggg tacttggtcc tgcaacaata atctgttctt cccgtctcaa atcatcaaag
    34921 aagaccggat tgcgcacaat ctctgaataa agaccttctg tcggaacaaa caagattcca
    34981 aagttggttg tccgaggtgg tgctatgtac ttgttcctaa tatccctagc aaagcgcttg
    35041 acgcttgcta ggagtgactt acgacagcgt tcaatctcat ccttgtcacc tgtctcatag
    35101 gcttcttcca agcggtaata atctgccagt ggaaacttag agtcaattgg cagatagacg
    35161 tattcttggt cgccttgtcc gggtaacttg atggcatact ccactcgttc actagagttt
    35221 tcaaccgttg cgtattctcg ttcgtactgg gcaggtgtca tgatgtcttc aataatttgc
    35281 cccagttgca attctcccag aatccctcgc gtcttggttc cagagagaac cttgttaaga
    35341 gctccgacat cacgggcaac tgtctgcatt tctccaaggc cacgattgac agactccagt
    35401 tgtttagaaa ctgtctcaaa ggaagcctgt aagcgtgtct gcaaggtctt ttctagtttt
    35461 tcctcgaccg tctggcgcat ttgttccaaa cgttgctcat ttgattcctg caaggcttgg
    35521 agacgttggt ctgtcttgtc tctagtttgg aggagattat ctgtcatttc ttgacggact
    35581 tgggtcagac cttggtgcaa ttcaatccgc acttcttgca aacggtcgct gacaaccact
    35641 tccaaatctt tttggtctaa ctggctggct tgtctggctt ggtcaaagcg gtaatccaac
    35701 tggtctgaca aatgatctgc ctgatcctcc aagctcttac ttaagtgttt ctcctgccta
    35761 tcctgccttt gccaaatcag aaagagacca gctagattgg caattaataa tagaataagt
    35821 aaactttcca tcctacctcc tgtccttgct atgcagtacg accacataac catctgggca
    35881 agttaccgac acttccctat ctatatattc gttagaagcg tacacttttt taaagaaaaa
    35941 attttcctct gtcaactcat acttggctcc aagaatagtc agctggctat cccgaactgg
    36001 cataaaggct agatagtcgt agtctgaacg aggttctagc tgactgattc cttctggaca
    36061 ataagtaatc aagttttgcc catcctcaat ttctatttga tgcatatagg atgccaactt
    36121 aggattgcta ggcagaaaga cattggccaa catatggtca atacggccac ccaaggcacc
    36181 gaaaatagta acctgagcct gaggattttg cttaaagatg gtcaagagag ccaattccaa
    36241 atcagtatca tctttttctg gccgggcttg gacaaaatac tgggcacgtt tttgaatcac
    36301 ctgtcgctct tcttccgtca cagaatcaaa atctccgact gctagagcaa gaggcaaatc
    36361 ttcttccaag atccagagcg agcctcgatc cacaccaaca aaaccatcaa agtccgtccg
    36421 ataatgaccg cggtctccgc ctgcaaaaac ggcaacccta gtccagttgt tttctgagag
    36481 tttgtactcg ctcattgaca tctcccttaa agacatagga acctgctaca aaaacggtcg
    36541 caccagcttc tttggcttga gcaatagttt ggtcatcaat cccaccatcc acttcaatct
    36601 caaagttcaa acctttttca tcacgaaggg caaccagctc acgaacctta tccatggttt
    36661 ctggcagaaa ggcttgacca ccaaatccag ggttaactgt catgactagg acttggtcaa
    36721 ctagatgaag cacatgctta atcgcttcaa ctggtgtacc aggattgata acaactgatg
    36781 gcttgacacc gagtgaacga atcttttgga gggcaccatg aatatgaggc gttgcttcca
    36841 catggatact aataatatcc gcacctgcac gcacaaagtc ctctaaatga tgctcagggt
    36901 ttgacaccat caagtggcag tcgaaaacca tcttactatg aggacgaaga gcttcgacca
    36961 cacccgcacc aaaactgatt tgcggcacaa aatgaccatc cataatatcg atatgggcat
    37021 actctgcccc agttgcttct aggcgtttaa tttcacgttc aaagttggca taatctgctg
    37081 ccagaattga cggagcaatc ttgtattgag acataggttt ctccttattt tggaattttt
    37141 ttgctgactt ttttataggt ttctctgcga ttttcaattt cgctgaggaa ttgcaggtag
    37201 ttgtcaaaac ggaagggcgc aatggtacct tcttcaactg ctggcttgac agcacaggac
    37261 ggctcatggg tatgggtaca agtacggaat ttgcagtctc gactgacagt ggcaatctct
    37321 ggaaaggcct gattgaggtc ttcagccgtt gatacttcat aatccagtga tgaaaagcct
    37381 ggtgtgtctg cgattttacc cccattgagg ttgtaaaaac taacagctcg agtggtatga
    37441 cgcccgcgac ccagactgtc tgaaatttct cccgtttcaa gattaagatc tggtgcgatt
    37501 ttattgagaa gagttgattt cccaacaccc gtctgcccca taaagaccgt aaccttgcct
    37561 gttaacaaag gcaggagttc ctctttactg gtcacaaagt catatccgat gtcaccatag
    37621 gtctgctggt aaaaatccag ttctcccccg tcttccaaca aatccatttt agaaatatag
    37681 acgatgggat gaataccctt atgctccaaa agaaccaaga aacgatccag caaattgctg
    37741 ttaaaatcag gttccttgac agacatgatt actacagctt ggtcgatatt gacaataggc
    37801 ggacggacca gactgttttt ccgttcgtga atcttgagaa tatagccttc tgaattttcc
    37861 tcggcagaga aatctaccca gtccccaacg taaggggtat gccctttttt acggaaattc
    37921 ccacgcgcgc gtgtttgata gacttggcca tcactctcta catagtagaa cccagccaag
    37981 gctttaatga tttgtccctg caaaataact cctttaaaat tgttagttcc attataacaa
    38041 aaaaaagcta ttttagctta gcttctcttt acaatttcga taagtctatt ctaaaagaaa
    38101 aagatacact cacgctttag ataccaagtt ttatacaaaa ataacgaatc tacctcctta
    38161 tataaaaaca ggcgaacaga gagcctaaaa ctccctgttc gctttacttt ttctgtgtgt
    38221 aatagaaaaa acctaataaa gcaagacaaa aaatatgaat ataaactcca tacatcatgt
    38281 ggggaaagac agactctata aaatagcctg gtagatagat gattggaaat tgatagaaat
    38341 cataggtcgt tagagatagt aaacaaagaa catacataaa tactgctaca attagaaccc
    38401 atccttgctt tcgccataga aaaatcatca ataagaacag acaaagtaga tagattgacc
    38461 aatttcgcaa cataaattga aaaccataaa tcatactttc agtcgtttct ccatcaatca
    38521 catcaactac tttatagaaa ggtaaacaat agctcactaa aaaaagaagg ggactaatta
    38581 tttttttcat attctctacc atggattatt ttgcaagtaa gctgaccatc tatctccata
    38641 tcgaatcaaa ttaacagtat aattagttac tacccgattt tcacctggtc caaccttaga
    38701 aaaacctgtg ctatactccc aactacttct tgcacctgga tgaaaccatt tttgctggga
    38761 tgaataccaa ccaccttgtc taacttccac acttgaagat tctatttcga tatccctttc
    38821 atggaagtca actcctccac ttattttagt aatatttttt tgtacacctc catcataact
    38881 cacccagtga acaacagtat acaattccac actataagta ctatcaaact gactttgatg
    38941 agtagtaatg ttttgagtat aagcgtgcac tttctgtata ccaaaaatat ggtctaatat
    39001 attcgttggt ttagcaagct tattgtaacc ctcttcaaca aaagtagcct tctctaaatc
    39061 agcggtataa acagtttttc cttgtactac ttgattgttt atagaagtaa tacggctatc
    39121 cacaacaatg ggggccacca tatctccatc gctagtttct attttagctg cctctttcac
    39181 ctcatataca actcgatttt cttcagactg aatcacttct accccatttt tttcaggtat
    39241 agataatcta gtttgcccat tagaaaccgt tatatttgga ccaatattct tctcatttgc
    39301 ataagtcgca ataggaaatc ctgatagaac cactgcacac ataaggctat tgactaattt
    39361 ttttctcatg aatatatcct tcccattttc aagaggagta aaaatagcta atataagatg
    39421 aacgtttcct tatatttcag aataggatat ctatctgaaa gcaattcaca ctcctataga
    39481 taactgttcc aaatcttggc tacatatatt tcaatagttt gctacaaaaa actcctttct
    39541 aagtctattg aacatgccct tattcaccta ctaatatatc acaaaaataa ataaatacaa
    39601 gactgttttt tctactagtt ttatgataga atagtattgt tagggtaaat ttcatatata
    39661 aatgtcgagt gaaaaatcga tggagcagaa atcggtagac aaagactcga tttcgttggt
    39721 ccagccccac aaggctaatc aggtatttca cgagtttaaa aatctaatga agtgcccaat
    39781 caactactga ttcattgatt taatacgaac tatagtggat tgaacctaga aatagtacac
    39841 taaggattct aaaacgtttc tagaaattaa tttgactttc ctaatctctt tgttcatatc
    39901 ttatttcaat ctactatata taccaaaatg ctaggacaaa agtctttaaa atcagagaaa
    39961 cgcatattat caggtgttgg aaaaccttga taatatgcgt tttatcatag aaagatctac
    40021 ttcatttttt actaaaatta agtttttgtc cctgcatctt agagtccttg ccctttaagt
    40081 gcatctgcta ggctggcaaa ctcttccaag ctgagagctt ccccacgcac acttggtgac
    40141 aagcctgctt ggtccaaagc cttggtcagc ttgtccttga cctcttcagt cttgccaaag
    40201 taacctgtca agttattcca caaggtcttg cggcgatggg taaaactagc cttggaaacc
    40261 ttaaagaaaa agttctcgtc ttccactgct acagctggca ctggacggcg caccattttc
    40321 aagatggctg agtctacatt tggtgctggc acaaagactg tacgcggcac gataaaggca
    40381 accttggctg tcatgtaata ctgcacagcg atagacaagc taccgtaagc cttggtattt
    40441 ggttgagccg agatacggtc cgccacttct ttttgcatca tgaccacaaa ctcactaaaa
    40501 ggaatgccac tctcgattaa gtgcatgaga ataggcgttg tgatgtagta aggcaaatta
    40561 gccactacct tgattggcag gtcaggattt ttgaaattct ggatatgttg cgccaaatcg
    40621 accttgagaa tgtcctcgtt gactacagtc acattgtcaa aatcacgcaa ggtatctgcc
    40681 aaaatcggta ccaaacgatg gtcgatctca aaggccataa cttctgctgc acgctcagcc
    40741 aaaaactcgg tcaaggcacc aatacctggc ccgatttcaa tgacattgac ctggtcatca
    40801 atctcagccg tatccacgat tttttgtagg atattggtat ccgtcaagaa attttgccca
    40861 aaggactttt taaaggtaaa accgtgacgc tccagcactg ccttggtcac gctataatct
    40921 gcaattctca tctattctct tttctattat ctgttactac tattgtaaca cattcccctt
    40981 gtattttggg ggtgaaaatc ataccaaaaa actatctttc ctcatgaaga aagatagtct
    41041 tggaaatctt taaaagtggc cttagcgctt ctctcgaaac atacgttcat actcttcgaa
    41101 aatctcttca aaccacgtca gcttcacctt gccgtactca agtacagcct gcggctagct
    41161 tcctagtttg ctctttgatt ttcattgagt atcaaaaaaa tcagcttctt gataacttcg
    41221 attttcgggt agggtcaaat ccacatcctc ctccacatca tccactgtca gttcaaccgt
    41281 ttgaggtaaa tttttcaaac gataatgctt ttgcctttgc ccttcactac tagcaaaatc
    41341 aagcaaatag ccatgcactc ggatttgaac caaaaggaga ggattggtca tattttccat
    41401 gatgaggata tcttataaac cacctctggc actaggataa tcagataccc tgcgaatacg
    41461 gattttttca cacatgagca agtttcctca tatcaatgat ttcatcagcc ttattccaga
    41521 ctaggggatt atgggtcgca atgatgataa ttcgattttc atctttcaaa tccaccaaga
    41581 gattcataac ctcctctgaa ttttcaggat caagagctgc tgttggttca tctgccaaaa
    41641 tcaagggtgg atttttcaaa atagttttcg caagggcaac tcgttgggcc tctcccccag
    41701 ataaagtata aattttttgt tctaaatcca aataccctag attaactttt tctaaagccc
    41761 ccacttgcct ttccaaacgt tctacttttg agattttctg accaacaaaa cccaaatcca
    41821 aattttcttt gattgattgg ttttctaaga ggccaaaatt ttgaaagaga tagcccatct
    41881 gatctcgaaa atactcacga gtgggaatgg tttttaaatc tttcccctga tagagaaccc
    41941 ttcctccatc tatcttttct agctttccca agatattcag cagcgtcgtc tttccgcttc
    42001 cactctttcc gattaaggca taaaccttgc ccttctccag cttgagattc aaaccagaga
    42061 aaatcgcgcg gtcattaaat ttcttttcca atccttgaat atcaatcatc ttattttcct
    42121 ttcaatactg ccatgctacc agcttcttct tttttgtcct gccttactaa aatcaagagg
    42181 gcgttaagcg taaacaaagc tacaactaga gcgctaatca aaccatctct tgtcaaaata
    42241 ctagatagga ctaggccaag caagagaact cctccttgcg ccagtaaata cttgccatga
    42301 agctcataga ttgtcatacc agcaagacgt ttaatcataa gctcccgtct gaactgctca
    42361 aaatagagaa gattcatgga atcaaataac aagatagccg tagacagggt caaaatcgtc
    42421 ccaataagga gagagtaaaa ctctacccgt ttgtcattta gtaccttggc aaaaaatagc
    42481 tggcttttta ccaagtaaga aaccttgtga tacagacctt gctcttttag agctgtgatg
    42541 ctgtctccat atcgatctag tttcaaggca ctattagccg tagttcccca caacatccct
    42601 gcaacaggtc ttgttccagt cgcttgcggc gttagaacta caataatcgg atcttttagg
    42661 tactggcgtg ttgtcttgta cccatcatta tagaggaaac gttcctgtcc tgtttctgta
    42721 aaagctagac ttacctgtgg gaggtagtat ttctgactcg tcacttctac actttcagat
    42781 gaaaagtttt gcaggtaatc tgtaaacaat ctttggtagt aggtagactg ctctcgcaag
    42841 ctctcaggca agattagccc aaactctccc tcagacaagt tttgcatctt gtccataaac
    42901 tctgaagaaa cggtaatctt ttcttctatc agatagcgtg gtgagacata gataacattc
    42961 cctgacggtg tgtagtcact gagacgattg ccatctaggt ccacttctgc tccgtctgag
    43021 aaattgtcaa cattgctcat aatataaaaa gagtctgtat tggctaaccg ttcttcagta
    43081 aatgtctgcc actcacgatt atccttacgc gttccttctt catcggcaaa tgcactagac
    43141 caaccaaagg atagacggta acggtctgag gactggctcc atttattgct agctctctcc
    43201 atttcctgca tttcacggta gtggggtagg agagctgtcg cactcgatcc gaccaccaat
    43261 acagctaaga gttgccccac catcatcaat gtcatcatac gtttgagagg gagtttccct
    43321 ttcaatagat ccaccagact attttcctgt aaaccaagta gatagacgac acttagtaag
    43381 gtagaaatcc ctgccagggt caatccataa agtagaagag caatgatgac cagttgcacc
    43441 gttgccataa acaaggcacc ttgataccag agaatcccca atcccaaaag actggatacc
    43501 agcactgagc agataaactg tctcacatct tctaacactg gtctgagagc aactccaaac
    43561 aagctctcac cagctattaa gcgaatccct gcctgacgaa gggatttgat ccgataaatc
    43621 agggtcagac tcataaaggt cagcagaaaa atagctaaac tcagtagcac cataggggtg
    43681 gccgccaata gtaagactat cgaaaatgga tcttctccat tcgaaacaaa gccttgatag
    43741 ccaagttctt tcaaggtggt ctgtaagctc actccatcca aacttcctga cacaatcaag
    43801 taagacccta ataaatcact cgtttctgca ctctccttgg aggaaatggt cagaccttct
    43861 ggaagctctc cctcaccata agtggcatag gtaaagagtg tttctccagc ttcatttggc
    43921 tcaacgattc gacgggcgat gagactatta tgctctaccg ccaagtgact caaaacctct
    43981 gtcacctctt cgcgactagc tactggttga tttatcatca ttcctgtcac atcaacagaa
    44041 ggatagttac caaataaaat ctcttctcga tggtcaacgg aagttatcac catataaagc
    44101 gataccaata ccattgaaat caaaataaat aaacgtttca tcatttcctc caaaaagtta
    44161 cttggtcact tagtgagaag gtgaccacag tcactgcgat gttaagaagc ttattaagtt
    44221 ctttctacta gcaacatctt caaatacatt atatccgttt tttcaagaac tatcaaggac
    44281 atcaatgtcc ttaaaatcta actatttcat attattttta gcttatatct aaaaaaacag
    44341 ttctaaagac gaactttaga actgttttga tacgaggaca aggacatttt tgtcactgat
    44401 tcactatgtt tataaatatt ttttgacatc ctcttgccat tcctctgtca atttctttac
    44461 tagaaatcca tctccaatta gcttcgcaaa tgttttagaa gactgataaa atgattcagc
    44521 taaactaaaa tctctttctt ctcttaatgc ttgcttccac aaaaacataa atacaagagg
    44581 tttcttttga taatcttgag ttttatccat aatttcttgt aaacacgata gataatcatt
    44641 aaaacaatca gttactccta ccttttcaag acaacacatt cctgaaataa gagtatctct
    44701 aattataaag aagttttcta atttagttac ctttttctgt tccaaaagaa agagcattag
    44761 cttttcgatt tgatttataa atttggcaag atcttttcta atgagcattt gataaaaaaa
    44821 caaacgaatc aacaacatat catttgttga ataaacttct ttttctatga tctgagacat
    44881 atgttcctca agtattaact ctgcatattc aggccttcta gttctagaag tatccaaaca
    44941 cgcctgcaat acttcacatg ctaattgttc ttctttagga agattatcaa agtatgtttt
    45001 ataaatctct tccaaacacg cttccttctt atcgtactcc tcttctttac catagattgg
    45061 ttcacgtaaa atctggtatt tcaattctaa ataagcagga ggaagagctg aaaaatccgg
    45121 cataaggcta taaactggaa ctcctagccg gcgagcaata taggctaact tgggcaaact
    45181 cggttgcgaa gctccacttt caattcgcga cagttgacga actgtcagtt cttgctcatc
    45241 tccacaaaaa tatggacgac taactccttt ttctatccga atctctttaa ttttttgacc
    45301 aattaacatc agacgcctcc tcttctacct gcttcgaaaa atactgtgaa acttaaaaaa
    45361 ttgtaacggc tacatctttc ctactcataa gatttcatag cttcttccac ttctgccaaa
    45421 gtaaccccaa acaactctag gcgtttgagg agttgcttgc cgttagaata gccgattcgg
    45481 agagtctctc cgagatattc tctacgctta cggctgtctg cccctgctag aaaaccaagg
    45541 cgaatcaagt cgctacgact aatgtcaaac tgactctcat gttcaaattg ttctgtcacc
    45601 tgagctagag ccgttttcag gtcttcatag ctggcatgct caattcccag agaacgcccc
    45661 ttggtcttgg actttggaac agcttcatct cgcttgagaa aggcatgccg aactgttgga
    45721 atggccgtca taatcatgcg ccgaatccgc tccccattaa aatctgggtc tgtaaagaca
    45781 atgactccct gacgttggtg caggcgctga atccgctcta tatcctgagc attgatggca
    45841 gaacctcgag tctcataggt ctccacatcg aaataacgtt tgagattgac cgtatcatca
    45901 cgcccttcaa ccacgataac ttgagaaatt ttctctttca ttacttgctg tccaatccaa
    45961 aaatgcgttc tgcatttgca gtcgttgcta ccgccagctc ttctgtcgtc ataccacgca
    46021 agtcagcgat aaagtcgacc acatagcgag tataggctgt tttattttca cgaccacgct
    46081 tgggtacagg tgctaagtaa ggcgcatctg tttccaccaa aatcttgtcc aaaggtaact
    46141 ctttagctgc ttcttggagg tcagttacct tcttaaaagt caccactcct gagaaggaaa
    46201 tggtcatacc aagatccaca aacttctctg cccactcaag cgtccctgaa aatgaatgca
    46261 tgataccacc acgaggacca acgccctcac tcttgataat ctcataggta tcttccagcg
    46321 catcacgggt atggacaaca aaaggcaaat ccaagtcctt agatagctga atctgacggc
    46381 gaaaaacctg ctcctgcacc tctttgggcg ctgtcatcca atggtaatct aagccaattt
    46441 cacctaaagc cacaaccttg ggatgtttta acttatccaa caagtaagcc tcaacttcct
    46501 ctgtataagt accagcttct gtaggatgcc aaccaatagt cgcatagagc tgatcatact
    46561 catctaccaa ctccaaggca cgctcaatcg tcggtttatc aaaaccaaca atattcatct
    46621 gtgtcacacc catctcagca gccaaggcaa tttcttctgc ctcacgacct gcaaattctt
    46681 ctacattcaa gtgtgtatgt gtatcaaaaa tcatctcttc taacctcgtt ttctatcttc
    46741 tattatacca aaaaagagga ggggcaccta atttttcggt ttcccctcct ctcttcaata
    46801 gagagctatt ctgctatctt ttctatccga tattgcccat ctcctattcc acagttagag
    46861 acagaagaga ttggctacat tgatagaata ttcctattca gctaaagtat gtgattatct
    46921 tgggttctca cttttctcac ccatcactag gattgatgac ttctcaaaat cccccttata
    46981 atctaacttt aagtagagaa tagaattttc tagctgttct attttctacg tctagtcttt
    47041 cttcctagca aagcaaaacc acttgttgcc accactagac caagactagc aagtgctgca
    47101 cttgatgctg aacctgtgtt aggtaattgt ttgccagcag gtgactggta ggtaacatct
    47161 tgcattgttc ctgcagttgc ttgcggtgca cttgttgtct taggagcagc attaggagcc
    47221 actggtctct taggaactgt aaccatgaca atggcttgca ctccaatcgt ttctgcttcc
    47281 ttcacatctt ccatagtttt cgcattttca atctctttga gagctgcttg tttttctgct
    47341 tccactcttg ctaaaagttc tgctttttct ttatcagaaa gcggtgcgcc tttgatttca
    47401 tcctgcttgt ccttggctgc tttttcaatg gcatttttag ctgattcttt ttcagtagct
    47461 aattgcttag aagcttgtga ttgagctgag ttttgtgaac ctgtgtgagc tgatccaccc
    47521 gcctggctac caccgcctgc attcgcatta gcatctgagc ttccagtatt gcctccctta
    47581 tctccacctg gtgtattttc tagcttatac tctggtgtag cttcttgagt tacagattca
    47641 cctttcgcag attgttgaac tgtatctttt cctagaatcg tcactactga accatctggg
    47701 aatgtgattg ttgctgtacc atctccagct acattgattg tcgctccgtc taatgctgaa
    47761 ccatttgctt gtaaaatagc aaccttaact ttttcttcat ctgttaaatg agttatatct
    47821 tttacatcta ctctttgagc aggtgcttta acagttgatt tttcagcagt cggtttagtg
    47881 ctatcttgtg cttttggatc ttgtgctacc aattgatttc ctggaattgt aatagctgaa
    47941 ccatctttaa agacgattgt cgctgcgcca tctccagcta cttcaacttt atagtaaaat
    48001 gaaataataa caggacaaat cgatcaggac agtcaaatcg atttctaaca atgttttaga
    48061 aatagaggtg tactattcta gtttcaatct actataacat cgcttccgaa tccatttgca
    48121 tctactgaac ttttttacaa aaataaaaat cagtagactc gagttcctac tgatttttga
    48181 tagaattcgt ttggattatg cagccaaaac tttgcgtcct ttacgacgac gagctgccaa
    48241 tacgcgacga ccatttttag ttgacatacg gttacggaat ccgtgtttgc gcgcacgacg
    48301 aagtttactt ggttgataag tacgtttcac gatgaatacc tcctcataga ttttgtattc
    48361 gtttagccgg ctataaagtg atcagttact aaacatactt tactattcta tctgattctt
    48421 tcacttttgt caatagctct aggcaaatgt ttccagcttt ttcgaatgca agcc
//
LOCUS       DAVBBO010000008        45779 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ST1
            SAMEA2066453-rid20184263.denovo.008, whole genome shotgun sequence.
ACCESSION   DAVBBO010000008 DAVBBO010000000
VERSION     DAVBBO010000008.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2066453
            Sequence Read Archive: ERR351777
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 45779)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 45779)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980402.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980402.1
            Genome Coverage       :: 176x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:17:33
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,141
            CDSs (total)                      :: 2,104
            Genes (coding)                    :: 1,953
            CDSs (with protein)               :: 1,953
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 16S)
            partial rRNAs                     :: 1 (23S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 151
            CDSs (without protein)            :: 151
            Pseudo Genes (ambiguous residues) :: 0 of 151
            Pseudo Genes (frameshifted)       :: 73 of 151
            Pseudo Genes (incomplete)         :: 76 of 151
            Pseudo Genes (internal stop)      :: 40 of 151
            Pseudo Genes (multiple problems)  :: 32 of 151
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..45779
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2066453-rid20184263.denovo.008"
                     /strain="ST1"
                     /db_xref="taxon:1313"
     gene            complement(1..190)
                     /locus_tag="VQU30_000455"
                     /pseudo
     CDS             complement(1..190)
                     /locus_tag="VQU30_000455"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus and C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase family protein"
     gene            complement(252..701)
                     /locus_tag="VQU30_000456"
     CDS             complement(252..701)
                     /locus_tag="VQU30_000456"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine/serine exporter family protein"
                     /protein_id="HET2446630.1"
                     /translation="MTLTTFLLQAVASFLAIITFLIVLNVQRSMLLPGGILGMTVWLI
                     YLLLKEPTNVIVATFIAAIIGSCVSQILSILYKTPAVVFILAILAPLVPGYLSYRTTA
                     FFVTGDYNKALASATLVVMLALVISIGMASGTVILRLYHYIKTHRVS"
     gene            complement(703..1461)
                     /locus_tag="VQU30_000457"
     CDS             complement(703..1461)
                     /locus_tag="VQU30_000457"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000392945.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine/serine exporter family protein"
                     /protein_id="HET2446631.1"
                     /translation="MEESKELNAVIDVIMLAGTILLKSGSEIHRVEDTMIRIAHSQGI
                     VDCNVLAMPAAIFFSIENTNISRMKRVTSSSYNIEKVCDVNQISRQLVGGQIDLETAF
                     KQLTALQAQPLPYTKLQVTLAATFSAPFFSVMFSGNIYDALGAGVATLFGFAFSLYVE
                     KFIRIPFVTAFAGAFVFGIIAQFWARYTGFPSTADLIIAGAVMPFVPGIALTNAVRDI
                     MTNHINSGMSKMFESLLITLALGAGTSVALVLMN"
     gene            complement(1576..3555)
                     /gene="pknB"
                     /locus_tag="VQU30_000458"
     CDS             complement(1576..3555)
                     /gene="pknB"
                     /locus_tag="VQU30_000458"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Stk1 family PASTA domain-containing Ser/Thr
                     kinase"
                     /protein_id="HET2446632.1"
                     /translation="MIQIGKIFAGRYRIVKQIGRGGMADVYLAKDLILDGEEVAVKVL
                     RTNYQTDPIAVARFQREARAMADLDHPHIVRITDIGEEDGQQYLAMEYVAGLDLKRYI
                     KEHYPLSNEEAVRIMGQILLAMRLAHTRGIVHRDLKPQNILLTPDGTAKVTDFGIAVA
                     FAETSLTQTNSMLGSVHYLSPEQARGSKATVQSDIYAMGIIFYEMLTGHIPYDGDSAV
                     TIALQHFQKPLPSVIAENPSVPQALENVIIKATAKKLTNRYRSVSEMYVDLSSSLSYN
                     RRNESKLIFDETSKADTKTLPKVSQSTLTSIPKVQAQTEHKSIKNPSQAVTEETYQPQ
                     APKKHRFKMRYLILLASLVLVAASLIWILSRTPATIAIPDVAGQTVAEAKATLKKANF
                     EIGEEKTEASEKVEEGRIIRTDPGAGTGRKEGTKINLVVSSGKQSFQISNYVGRKSSD
                     VIAELKEKKVPDNLIKIEEEESNESEAGTVLKQSLPEGTTYDLSKATQIVLTVAKKAT
                     TIQLGNYIGRNSTEVISELKQKKVPENLIKIEEEESSESEPGTIMKQSPGAGTTYDVS
                     KPTQIVLTVAKKVTSVAMPSYIGSSLEFTKNNLIQIVGIKEANIEVVEVTTAPAGSVE
                     GMVVEQSPRAGEKVDLNKTRVKISIYKPKTTSATP"
     gene            complement(3552..4292)
                     /locus_tag="VQU30_000459"
     CDS             complement(3552..4292)
                     /locus_tag="VQU30_000459"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397383.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Stp1/IreP family PP2C-type Ser/Thr phosphatase"
                     /protein_id="HET2446633.1"
                     /translation="MEISLLTDVGQKRTNNQDYVNHYVNRAGRTMIILADGMGGHRAG
                     NIASEMAVTDLGVAWVDTQIDTVNEVREWFAHYLEIENQKIHQLGQDEAYRGMGTTLE
                     VLAIIDNQAIYAHIGDSRIGLIRGEEYHQLTSDHSLVNELLKAGQLTPEEAEAHPQKN
                     IITQSIGQKDEIQPDFGTVILESGDYLLLNSDGLTNMISGSEIRDIVTSDIPLADKTE
                     TLVRFANNAGGLDNITVALVFMNEEDAE"
     gene            complement(4307..5620)
                     /gene="rsmB"
                     /locus_tag="VQU30_000460"
     CDS             complement(4307..5620)
                     /gene="rsmB"
                     /locus_tag="VQU30_000460"
                     /EC_number="2.1.1.176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255437.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (cytosine(967)-C(5))-methyltransferase
                     RsmB"
                     /protein_id="HET2446634.1"
                     /translation="MTKVETARSLALAVLEDVFVNQAYSNIALNKHLKGSQLSAADKG
                     LVTELVYGTVARKLTLEWYLSHFIEDRDQLDSWLYVLLLMSAYQLRYLDKIPDHAVVN
                     EAVELAKLRKKGSEKLVNAVLRRILREGWPDIASIKRKNKRDSIAYSLPVWLVAKLKE
                     EYGEERAKAIFESLLVRNKASIRVTDLSRKEEIQALLEANNSLLATTGLVKEQGHFAG
                     HNLFADGAITIQDESSQLVAPTLDLQGDERVLDACAAPGGKTAHIASYLTTGQVTALD
                     LYDHKLDLIQENAQRLGVEDRVQTQKLDARKVHEFFDQDSFDKILVDAPCSGIGLLRR
                     KPDIKYNKETADFASLQEIQLEILGSVCQILGKGGIITYSTCTIVSEENFQVVKAFLE
                     SHPEFEQVKLEHECKDIMKDGCILITPELYGSDGFFISQFRKISD"
     gene            complement(5613..6548)
                     /locus_tag="VQU30_000461"
     CDS             complement(5613..6548)
                     /locus_tag="VQU30_000461"
                     /EC_number="2.1.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000163675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionyl-tRNA formyltransferase"
                     /protein_id="HET2446635.1"
                     /translation="MTKLIFMGTPDFSATVLKGLLTDDRYEILAVVTQPDRAVGRKKV
                     IQETPVKQAAKEAGLSIYQPEKLSGSPEMEELMKLGADGIVTAAFGQFLPSKLLDSMD
                     FAVNVHASLLPRHRGGAPIHYALIQGDEEAGVTIMEMVKEMDAGDMISRRSIPITDED
                     NVGTLFEKLALVGRDLLLDTLPAYIAGDIKPEPQDTSQVTFSPNIKPEEEKLDWNKTN
                     RQLFNQIRGMNPWPVAHTFLKGDRFKIYEALPVEGQGNPGEILSIGKKELIVATAEGA
                     LSLKQVQPAGKPKMDIASFLNGVGRTLTVGERFGD"
     gene            complement(6561..8957)
                     /locus_tag="VQU30_000462"
     CDS             complement(6561..8957)
                     /locus_tag="VQU30_000462"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001162119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="primosomal protein N'"
                     /protein_id="HET2446636.1"
                     /translation="MALAKIIVDVPLMQTDQPYSYRIPEEFEGMLEVGMRVHVPFGKG
                     NRLIQGIVLGLKSQSDGEEMEQDLKDIAEVLDFSPVLTPEQLWLAEELRKSVFSYKIS
                     ILKAMLPGFLNSSYDKILYPLEGLSQEERVRLFGSEDSLAFSSLDLAKQAEMMRLTRK
                     GLLGLEYQAVDQKKVKTQSWYEVDHAQLEGVEISTRAKKKLELRDYLLSHPESASLAS
                     LLESYSREQVNFFVDQGTVTIVQKEVQRSAAYFEGIEASRPLELNPEQRQARDAVVSS
                     IGSSQPPFLLQGITGSGKTEVYLQIIQGALDKGKTAILLVPEISLTPQMTERFIARFG
                     DKVAILHSGLSNGEKYDEWRKVERGDAQVVVGARSAIFAPLKNLGVMIIDEEHEAAYK
                     QDSNPRYHAREVAILRAQYNQATLVLGSATPSLESRARAGKGVYQHLRLTQRANPLAT
                     IPEVQVIDFRDYIGQNETSNFTPPLLEAIQDRLVKKEQVVLMLNRRGYSSFVMCRECG
                     TVDTCPNCDISLTLHMDTKTMNCHYCGFSKDIPQVCPNCKSRSIRYYGTGTQKAYDEL
                     AELFPQARILRMDVDTTRKKGSHQALLDQFGRGEADILLGTQMIAKGLDFPNVTLVGV
                     LNADTALNLPDFRSSERTFQLLTQVAGRAGRAEKAGQVLIQSYNSQHYAIRFAKDQDY
                     EGFYAYEMGIRRQLGYPPYYFTIGITLSHKKEEEVFKRAYEVMNILRSGLSETSPILG
                     PTPKPIARTHNLYHYQILIKYRLEDELGPTLNQVLALTQERENSELRLSIDHEPQQFL
                     "
     gene            complement(9023..9337)
                     /locus_tag="VQU30_000463"
     CDS             complement(9023..9337)
                     /locus_tag="VQU30_000463"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001817694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit omega"
                     /protein_id="HET2446637.1"
                     /translation="MMLKPSIDTLLDKVPSKYSLVILEAKRAHELEAGAPATQGFKSE
                     KSTLRALEEIESGNVTIHPDPEGKREAVRRRIEEEKRRKEEEEKKIKEQIAKEKEDGE
                     KI"
     gene            complement(9362..9988)
                     /gene="gmk"
                     /locus_tag="VQU30_000464"
     CDS             complement(9362..9988)
                     /gene="gmk"
                     /locus_tag="VQU30_000464"
                     /EC_number="2.7.4.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000775037.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="guanylate kinase"
                     /protein_id="HET2446638.1"
                     /translation="MADRGLLIVFSGPSGVGKGTVRREIFESSENQFQYSVSMTTRAQ
                     RPGEVDGVDYFFRTREEFEELIRQGQMLEYAEYVGNYYGTPLTYVNETLDKGIDVFLE
                     IEVQGALQVKKKVPDAVFIFLTPPDLDELQDRLVGRGTDSAEVIAQRIEKAKEEIALM
                     REYDYAIVNDQVPLAAERVKCVIEAEHFCVDRVIGHYQEMLPKSPTTR"
     gene            complement(10118..11731)
                     /locus_tag="VQU30_000465"
     CDS             complement(10118..11731)
                     /locus_tag="VQU30_000465"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520539.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease Y"
                     /protein_id="HET2446639.1"
                     /translation="MEIMSLAIAVFAVIIGLVIGYVSISAKMKSSQEAAELMLLNAEQ
                     EATNLRGQAEREADLLVNEAKRESKSLKKEALLEAKEEARKYREEVDAEFKSERQELK
                     QIESRLTERATSLDRKDDNLTSKEQTLEQKEQSISDRAKNLDAREEQLEEVERQKEAE
                     LERIGALSQAEARDIILAQTEENLTREIASRIREAEQEVKERSDKMAKDILVQAMQRI
                     AGEYVAESTNSTVHLPDDTMKGRIIGREGRNIRTFESLTGVDVIIDDTPEVVTLSGFD
                     PIRREIARMTMEMLLKDGRIHPARIEELVEKNRQEIDNKIREYGEAAAYEIGAPNLHP
                     DLMKIMGRLQFRTSYGQNVLRHSIEVAKLAGIMASELGENAALARRAGFLHDIGKAID
                     HEVEGSHVEIGMELARKYKEPPVVVNTIASHHGDVEAESVIAVIVAAADALSAARPGA
                     RSESLESYIKRLHDLEEIANGFEGVQTSFALQAGREIRIMVNPGKIKDDKVTILAHKV
                     RKKIENNLDYPGNIKVTVIRELRAVDYAK"
     gene            complement(11922..12176)
                     /locus_tag="VQU30_000466"
                     /pseudo
     CDS             complement(11922..12176)
                     /locus_tag="VQU30_000466"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006152757.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="Txe/YoeB family addiction module toxin"
     gene            complement(12180..12434)
                     /locus_tag="VQU30_000467"
     CDS             complement(12180..12434)
                     /locus_tag="VQU30_000467"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000388574.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system Phd/YefM family
                     antitoxin"
                     /protein_id="HET2446640.1"
                     /translation="MEAVLYSTFRNHLKDYMKKVNDEFEPLTVVNKNPDEDIVVLSKS
                     EWDSIQETLRIAQNKELSDKVLRGMAQVRAGSTQVHVIEE"
     gene            complement(12672..13769)
                     /locus_tag="VQU30_000468"
     CDS             complement(12672..13769)
                     /locus_tag="VQU30_000468"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000156376.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyltransferase"
                     /protein_id="HET2446641.1"
                     /translation="MTITGIIAEFNPFHNGHKYLLDQAEGLKIVAMSGNFMQRGEPAI
                     VDKWTRAQMALENGADLVVELPFLVSVQAADFFGQGAVDILDRLGIDSLVFGTEEVLD
                     YQKIADLYTEKGAEMEKFVKNLPDSLSYPQKTQAMWKEFAGLDFSGNTPNHVLALAYA
                     KAVAGRNIKLHPIQRQGAGYHSVNKDVDFASATALRQHQKDQDFLERFMPSVALFEQA
                     SKVIWEDYFPLLRYQILSNPDLTTIYQVNQEMAVRIKEAIKTAQSVEELVELVTTKRY
                     TKARVRRLLTYILVQARENVLPEAIHVLGFTEKVRQHLKSLKGQVNLVSRIGKEPWDA
                     MTQKADQIYQLGKPSIAEQNFGRVPIRIETN"
     gene            complement(13779..14519)
                     /locus_tag="VQU30_000469"
     CDS             complement(13779..14519)
                     /locus_tag="VQU30_000469"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001823113.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HET2446642.1"
                     /translation="MATYETFAAVYDAVMDDSLYDKWTNFSLRHLPKTKERKKLLELA
                     CGTGIQSVRFSQAGFDVTGLDLSADMLKIAEKRATSAKQKIAFIEGNMLNLSKAGKYD
                     FVTCYSDSICYMQDEVEVGDVFKDVYNALNEEGVFIFDVHSTYQTDEVFPGYSYHENA
                     EDFAMLWDTYEDEVPHSIVHELTFFIKEADGSFSRHDEVHEERTYEILTYDILLEQAG
                     FKSFKLYADFEDKEPTETSTRWFFVAQK"
     gene            complement(14839..15192)
                     /gene="rsfS"
                     /locus_tag="VQU30_000470"
     CDS             complement(14839..15192)
                     /gene="rsfS"
                     /locus_tag="VQU30_000470"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001003018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome silencing factor"
                     /protein_id="HET2446643.1"
                     /translation="MNEKELLELVVKAADEKRAEDILALDVQDLTSVTDYFVITSSMN
                     SRQLDAIAANIREKVAQAGFKGSHVEGDAAGGWVLLDLGAVVVHIFSEEMRAHYNLEK
                     LWHEANSVDISEALA"
     gene            complement(15205..15705)
                     /locus_tag="VQU30_000471"
     CDS             complement(15205..15705)
                     /locus_tag="VQU30_000471"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000844697.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine hydrolase"
                     /protein_id="HET2446644.1"
                     /translation="MKTAFIIIDVQNILVETGFQTKSLLGKISYLQNQARSKNIEIIY
                     VQHIENSEAQTSEDWQLSALLNRKPAEKVFQKKYNSIFKETGLKEYLDKQGIEKLVLC
                     GMQTEYCVDTSVKVAFEYGYQLIVPEGAVTTFDGDDIPAETINEFYEDIWEERFADVL
                     DYKHIF"
     gene            complement(15706..16299)
                     /gene="yqeK"
                     /locus_tag="VQU30_000472"
     CDS             complement(15706..16299)
                     /gene="yqeK"
                     /locus_tag="VQU30_000472"
                     /EC_number="3.6.1.41"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000331212.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bis(5'-nucleosyl)-tetraphosphatase (symmetrical)
                     YqeK"
                     /protein_id="HET2446645.1"
                     /translation="MSYQDYINCSREALLEKMAEFLPEKRLTHCLGVERAAMELAQRF
                     GVDVEKASLAGLLHDYAKKLSNQEFLALIDRYQLDPDLKNWGNNVWHGMVGIYKIQED
                     LDLHDSEILRAIEVHTVGAGQMTDLDKVIYVADYIEHNRAFPGVDVAREIANLSLNKA
                     VAYETARTVEYLAHQGFPIYPQTLETYNAFVHYLKEN"
     gene            complement(16299..16928)
                     /locus_tag="VQU30_000473"
     CDS             complement(16299..16928)
                     /locus_tag="VQU30_000473"
                     /EC_number="2.7.7.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000151307.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinate-nucleotide adenylyltransferase"
                     /protein_id="HET2446646.1"
                     /translation="MTIELLTPFTKVELEPEIKEKKRKQVGILGGNFNPVHNAHLIVA
                     DQVRQQLGLDQVLLMPEYQPPHVDKKETIPEHHRLKMLELAIEGIDGLVIETIELERK
                     GISYTYDTMKILTEKNPDTDYYFIIGADMVDYLPKWYRIDELVDMVQFVGVQRPRYKV
                     GTSYPVIWVDVPLMDISSSMVRDFLAQGRKPNFLLPQPVLDYIEKEGLY"
     gene            complement(16980..17291)
                     /gene="yhbY"
                     /locus_tag="VQU30_000474"
     CDS             complement(16980..17291)
                     /gene="yhbY"
                     /locus_tag="VQU30_000474"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000060164.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome assembly RNA-binding protein YhbY"
                     /protein_id="HET2446647.1"
                     /translation="MSLASKQRAFLNSQAHTLKPIIQIGKNGLNDQIKTSVRQALDAR
                     ELIKVTLLQNTDENIHEVAEILEEEIGVDTVQKIGRILILFKQSSKKENRKISKKVKE
                     I"
     gene            complement(17505..18611)
                     /gene="yqeH"
                     /locus_tag="VQU30_000475"
     CDS             complement(17505..18611)
                     /gene="yqeH"
                     /locus_tag="VQU30_000475"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000391231.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTPase YqeH"
                     /protein_id="HET2446648.1"
                     /translation="MEEILCIGCGATIQTTDKAGLGFTPQSALEKGLETGEVYCQRCF
                     RLRHYNEITDVQLTNDDFLKLLHEVGDSDALVVNVIDIFDFNGSVIPGLPRFVSGNDV
                     LLVGNKKDILPKSVKSGKISQWLMKRAHEEGLRPVDVVLTSAQNKHAIKEVIDKIEHY
                     RKGRDVYVVGVTNVGKSTLINAIIQEITGDQNVITTSRFPGTTLDKIEIPLDDGSYIY
                     DTPGIIHRHQMAHYLTAKNLKYVSPKKEIKPKTYQLNPEQTLFLGGLGRFDFIAGEKQ
                     GFTAFFDNELKLHRSKLEGASAFYDKHLGTLLTPPNSKEKEDFPRLVQHVFTIKDKTD
                     LVISGLGWIRVTGTAKVAVWAPEGVAVATRKAII"
     gene            complement(18614..19204)
                     /locus_tag="VQU30_000476"
     CDS             complement(18614..19204)
                     /locus_tag="VQU30_000476"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YqeG family HAD IIIA-type phosphatase"
                     /protein_id="HET2446649.1"
                     /translation="MDCFILVTKENCEKKLRKGARMAIENYIPDFAVEAVYDLTVPSL
                     QAQGIKAVLVDLDNTLIAWNNPDGTPEMKQWLHDLRDAGIGIIVVSNNTKKRVQRAVE
                     KFGIDYVYWALKPFTFGIDRAMKEFHYDKKEVVMVGDQLMTDIRAAHRAGIRSILVKP
                     LVQHDSIKTQINRTRERRVMRKITEKYGPITYKKGI"
     gene            complement(19156..20064)
                     /locus_tag="VQU30_000477"
     CDS             complement(19156..20064)
                     /locus_tag="VQU30_000477"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000242243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium transporter CorA family protein"
                     /protein_id="HET2446650.1"
                     /translation="MVLEKQLGHGCTWIDLDLGKLNKLEDLSEIYGLDKETIEYALDR
                     NERAHMDYHRESGTVTFIYNVLDVKKDKAYYETFPMTFIVEHRRLITISNTKNAYVIE
                     QMTRYLESHDTLSIYKFLFASLEIISNAYYPVIEQMDKSRDEVNDLLRQRTTKKNLFA
                     LSDLETGMVYLTAAAKQNRILLEHIQGHALYRSFDEIEREQFDDAMIEAHQLVSMTDL
                     ISQILQQLSASYNNILNNNLNDNLTTLTIISVLLAVLAVVTGFFGMNVPLPLTDEPHA
                     WLYISLASAGLWIVLSLLLRKIAKKS"
     gene            complement(20121..20681)
                     /locus_tag="VQU30_000478"
     CDS             complement(20121..20681)
                     /locus_tag="VQU30_000478"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mechanosensitive ion channel"
                     /protein_id="HET2446651.1"
                     /translation="MQKFIQAYIEKLDVTTIIENILTKVISLLLLLIVFYIAKKMLHT
                     MVQRIVKPSLKMSRHDVGRQKTISRLLENVFNYTLYFFLLYCILSILGLPVSSLLAGA
                     GIAGVAIGMGAQGFLSDVINGFFILFERQLDVGDEVVLTNGPITVSGKVVSVGIRTTQ
                     LRSEEQALHFVPNRNITVVSNFSRTD"
     gene            20820..22029
                     /gene="sstT"
                     /locus_tag="VQU30_000479"
                     /pseudo
     CDS             20820..22029
                     /gene="sstT"
                     /locus_tag="VQU30_000479"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000713440.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="serine/threonine transporter SstT"
     gene            22097..23050
                     /locus_tag="VQU30_000480"
     CDS             22097..23050
                     /locus_tag="VQU30_000480"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000028179.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aromatic acid exporter family protein"
                     /protein_id="HET2446652.1"
                     /translation="MSISQRTTKLILATCLACLFAYFLNLSSAVSAGIIALLSLSDTR
                     RSTLKLARNRLFSMLLALAIGVLAFHLSGFHIWSLGLYLAFYVPLAYKMGWEIGITPS
                     TVLVSHLLVQESTSPDLLVNEFLLFAIGTGFALLVNLYMPSREEEIQHYHTLVEEKLK
                     DILQRFKYYLSRGDGRNRAQLVAELDTLLKEALRLVYLDHSDHLFHQTDYHIHYFEMR
                     QRQSRILRNMAQQINTCHLAASESLILAQLFSKIAGQLSQTNPASDLLDEIERYLEVF
                     RNRSLPKTREEFETRATLLQLLREAKTFIQVKVDFYQKYRQ"
     gene            complement(23286..23366)
                     /locus_tag="VQU30_000481"
                     /pseudo
     CDS             complement(23286..23366)
                     /locus_tag="VQU30_000481"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820552.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopyranose mutase"
     gene            complement(23421..23645)
                     /locus_tag="VQU30_000482"
     CDS             complement(23421..23645)
                     /locus_tag="VQU30_000482"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000571861.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="accessory secretory protein Asp5"
                     /protein_id="HET2446653.1"
                     /translation="MIEMLIVLAIILSLALIVLVTIQPRQNQLFSMDATSNIGKPSYW
                     QSNTLVKVLTLLVSLALFVLLLTFMVITYK"
     gene            complement(23650..23829)
                     /gene="asp4"
                     /locus_tag="VQU30_000483"
     CDS             complement(23650..23829)
                     /gene="asp4"
                     /locus_tag="VQU30_000483"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001287962.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="accessory secretory system protein Asp4"
                     /protein_id="HET2446654.1"
                     /translation="MSEEDLFYKDVEGRMEELKQKPIKKEKETRGEKISKTFSLLLGL
                     MILIGLLFTLLGILR"
     gene            complement(23831..25168)
                     /gene="gtfB"
                     /locus_tag="VQU30_000484"
     CDS             complement(23831..25168)
                     /gene="gtfB"
                     /locus_tag="VQU30_000484"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000571772.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="accessory Sec system glycosylation chaperone
                     GtfB"
                     /protein_id="HET2446655.1"
                     /translation="MIELYDSYSQESRDLHESLVATGLSQLGVVIDADGFLPDGLLSP
                     FTYYLGYEDGKPLYFNQVPVSDFWEILGDNQSACIEDVTQERAVIHYVDGMQARLVKQ
                     VDWKDLEGRVRQVDHYNRFGACFAKTTYSADSEPIMTVYQDVNGQQVLLENHVTGDIL
                     LTLPGQSMRYFANKVEFITFFLQDLEIDTSQLIFNTLATPFLVSFHHPDKSGSDVLVW
                     QEPLYDAIPGNMQLILESDNVRTKKIIIPNKATYERALELTDEKYHDQFVHLGYHYQF
                     KRDNFLRRDALILTNSDQIEQVEAIVEALPDVTFRIAAVTEMSSKLLDMLRYPNVVLY
                     QNASPQKIQELYQLSDIYLDINHSNELLQAVRQAFEHNLLILGFNQTVHNRLYIAPEH
                     LFESSEVAALVETIKLALSDVDQMRQALGKQGQHANYVDLVRYQEIMQTVLGG"
     gene            complement(25161..26672)
                     /gene="gtfA"
                     /locus_tag="VQU30_000485"
     CDS             complement(25161..26672)
                     /gene="gtfA"
                     /locus_tag="VQU30_000485"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260822.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="accessory Sec system glycosyltransferase GtfA"
                     /protein_id="HET2446656.1"
                     /translation="MTIYNINLGIGWASSGVEYAQAYRAGVFRKLNLSSKFIFTDMIL
                     ADNIQHLTANIGFDDNQVIWLYNHFTDIKIAPTSVTVDDVLAYFGGEESHREKNGKVL
                     RVFFFDQDKFVTCYLVDENKDLVQHAEYVFKGNLIRKDYFSYTRYCSEYFAPKDNVAV
                     LYQRTFYNEDGTPVYDILMNQGKEEVYHFKDKIFYGKQAFVRAFMKSLNLNKSDLVIL
                     DRETGIGQVVFEEAQTAHLAVVVHAEHYSENATNEDYILWNNYYDYQFTNADKVDFFI
                     VSTDRQNEVLQEQFAKYTQHQPKIVTIPVGSIDSLTDSSQGRKPFSLITASRLAKEKH
                     IDWLVKAVIEAHKELPELTFDIYGSGGEDSLLREIIANHQAEDYIQLKGHAELSQIYS
                     QYEVYLTASTSEGFGLTLMEAIGSGLPLIGFDVPYGNQTFIEDGQNGYLIPSSSDHVE
                     DQIKQAYAAKICQLYQENRLEAMRAYSYQIAEGFLTKEILEKWKKTVEEVLHD"
     gene            complement(26684..29056)
                     /gene="secA2"
                     /locus_tag="VQU30_000486"
     CDS             complement(26684..29056)
                     /gene="secA2"
                     /locus_tag="VQU30_000486"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000489793.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="accessory Sec system translocase SecA2"
                     /protein_id="HET2446657.1"
                     /translation="MFRRLGQDFQLRKVKKILKQINALKGKMSSLSDQELVAKTVEFR
                     QRLSEGESLDDILVEAFAVVREADKRILGMFPYDVQVMGAIVMHYGNVAEMNTGEGKT
                     LTATMPVYLNAFSGEGVMVVTPNEYLSKRDAEEMGQVYRFLGLTIGVPFTEDPKKEMK
                     AEEKKLIYASDIIYTTNSSLGFDYLNDNLASNEEGKFLRPFNYVIIDEIDDILLDSAQ
                     TPLIIAGSPRVQSNYYAIIDTLVTTLVEGEDYIFKEEKEEVWLTTKGAKSAENFLGID
                     NLYKEEHASFARHLVYAIRAHKLFTKDKDYIIRGNEMVLVDKGTGRLMEMTKLQGGLH
                     QAIEAKEHVKLSPETRAMASITYQSLFKMFNKISGMTGTGKVAEKEFIETYNMSVVRI
                     PTNRPRQRIDYPDNLYITLPEKVYASLEYIKQYHAKGNPLLVFVGSVEMSQLYSSLLF
                     REGIAHNVLNANNAAREAQIISESGQMGAVTVATSMAGRGTDIKLGKGVAELGGLIVI
                     GTERMESQRIDLQIRGRSGRQGDPGMSKFFVSLEDDVIKKFGPSWVHKKYKDYQVQDM
                     TQPEVLKGRKYRKLVEKAQHASDSAGRSARRQTLEYAESMNIQRDIVYKERNRLIDGS
                     RDLEDVVVDIIERYTEEVAADHYASRELLFHFIVTNISFHVKEVPDYIDVTDKTAVRS
                     FMKQVIDKELSEKKELLNQHDLYEQFLRLSLLKAIDDNWVEQVDYLQQLSMAIGGQSA
                     SQKNPIVEYYQEAYAGFEAMKEQIRADMVRNLLMGLVEVTPKGEIVTHFP"
     gene            complement(29049..29489)
                     /gene="asp3"
                     /locus_tag="VQU30_000487"
     CDS             complement(29049..29489)
                     /gene="asp3"
                     /locus_tag="VQU30_000487"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="accessory Sec system protein Asp3"
                     /protein_id="HET2446658.1"
                     /translation="MIITQRQSIYWGEVGGTYMYGTTVSYYLDKSVRLYNPLLPSGEI
                     LKTWFSSVNYQAARTQPQLPLLKRKQEYQLSLVFDCQPENGVYTKITFFDRYGDILEK
                     KVEKAKDFIFTYPEDSYTYQVSLLSAGFESLTFYHFSIKEIRSV"
     gene            complement(29486..31021)
                     /gene="asp2"
                     /locus_tag="VQU30_000488"
     CDS             complement(29486..31021)
                     /gene="asp2"
                     /locus_tag="VQU30_000488"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000032116.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="accessory Sec system protein Asp2"
                     /protein_id="HET2446659.1"
                     /translation="MSKELNILQIGLANWENHYDIPENMSWYYFYPNSSKTLREIIEK
                     EDINRFHAVLIEDGQYSRDLFSYVKYFEPYTLFYNQNLQINDREVVDFLKKRCAQAID
                     FLSPQQLINDLSKSLFGGGYGDKLFPPTIQVNPNFTGAISYQGLDYVSLEGEFGQDFA
                     QLAYWAYNIMVQKTLPIELWLEYEKEGNCDFRLVIRKMWSGSVDDFFEEVIVSEKDLE
                     QALFMDSRDGDYFLSISVEARGRGTIKLGNLHQRWSRKQFGKFVLGGNILHDSKRDEI
                     NYFFHPGDFKPPLTVYFAGYRPAEGFEGYFMMKTLGCPFILFSDPRLEGGAFYLGTDE
                     LEGKVKDTITHYLDYLGFDHKDLILSGLSMGTFPALYYGASFEPHAIIVGKPLANLGT
                     IASRGRLDAPGVSNLAFDCLIHHTGGTSSQDMTELDQRFWKIFKQANFSKTTFGLSYM
                     KDEEMDPQAYEQLVSYLCNTGAKILSKGTAGRHNDDTDTNISWFLHFYRMVLETGFGR
                     EKR"
     gene            complement(31005..32585)
                     /gene="asp1"
                     /locus_tag="VQU30_000489"
     CDS             complement(31005..32585)
                     /gene="asp1"
                     /locus_tag="VQU30_000489"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000291149.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="accessory Sec system protein Asp1"
                     /protein_id="HET2446660.1"
                     /translation="MYYFIPAWYGSERTWHADITPWYFSHFRLEFDDTFHQIRLFQEQ
                     DIDSRLLVLAYQPHLRYFLYRHGVLETDTYSVFDVMQDFHNLHTQVLSIRDIEWDDDC
                     EFIYSPFTIIVQKNGKKFAKVEHGVEGFISDIQYFEPNGQIHMHHIMDDRGFISSIIF
                     FEDGQAAYQEYLNPKGVWQFRERLKEGGQVEVNPILGYRFKMLTYQNMGDLVAEFFEN
                     YLQTYVKDQDIFMLPSHSHHDQLVLDRLPSTNPKLLSLFIGRNPQDTFRDLDVTFEKS
                     DLILVDREDSLRLLQELYPERMHQCYHLSSFDTRLRLGRSQTKKESIIYFQLDFEQGI
                     DNQALLQVLSFVAENKDTEVIFGAFAASQEQMNEVEGIVESFIQENIQSENLGKAIDY
                     GDAENPLEENQHQDLRLQFVNLNDELDLIKTLEFVRLIVDLNRHPHLYTQIAGISAGI
                     PQINLVETVYVEHLKNGYLLTDVTEFSKAAHYYTDRLKEWNESLIYSIDKIKEHTGQQ
                     FLGKLEKWIEEVKNVKGT"
     gene            complement(32595..33812)
                     /gene="secY2"
                     /locus_tag="VQU30_000490"
     CDS             complement(32595..33812)
                     /gene="secY2"
                     /locus_tag="VQU30_000490"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000161857.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="accessory Sec system protein translocase subunit
                     SecY2"
                     /protein_id="HET2446661.1"
                     /translation="MTKIYSSIAVKKGLFTLFLLFIYVLGSRITLPFVDLNTKDFLGG
                     STAYLAFSAALTGGNLRSLSIFSVGLSPWMSAMILWQMFSFSKRLGLTSTSIEIQDRR
                     KMYLTLMIAVIQSLAVSLRLPVQSSYSAILVVLMNTILLIAGTFFLVWLSDLNASMGI
                     GGSIVILLSSMVLNIPQDVLETFQTVHIPTGIIVLLALLTLVFSYLLALMYRARYLVP
                     VNKIGLHNRFKRYFYLEIMLNPAGGMPYMYVMSFLSVPAYLFILLGFIFPNHSGLAAL
                     SKEFMIGKPLWVYVYISVLFLFSIIFAFVTMNGEEIADRMKKSGEYIYGIYPGADTSR
                     FINRLVLRFSVIGGLFNVVMAGGPMLFVLFDEKLLRLAMIPGLFMMFGGMIFTIRDEV
                     KALRLNETYKPLI"
     gene            complement(33869..34546)
                     /locus_tag="VQU30_000491"
     CDS             complement(33869..34546)
                     /locus_tag="VQU30_000491"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820392.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HET2446662.1"
                     /translation="MGISVAKGEYITIVDSDDIVKENMIETLYQQVQEKDADVVIGNY
                     YNYDESDGNFYFYVTGQDFCVEELAIQEIMNRQAGDWKFNSSAFILPTFKLIKKELFN
                     EVHFSNGRRFDDEATMHRFYLLASKIVFINDNLYLYRRRSGSIMRTEFDLSWARDIVE
                     VFSKKISDCVLAGLDVSVLRIRFVNLLKDYKQTLEYHQLTDTEEYKDICFRLKLFFDA
                     EQRNGKS"
     gene            complement(34531..34773)
                     /locus_tag="VQU30_000492"
     CDS             complement(34531..34773)
                     /locus_tag="VQU30_000492"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844151.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HET2446663.1"
                     /translation="MSELISVVVPIYNTGKYLVECVEHILKQTYQNIEIILVDDGSTD
                     NSGEICDAFMMQDNRVRVLHQENKGGQHKLKIWGLV"
     gene            complement(34773..35969)
                     /locus_tag="VQU30_000493"
     CDS             complement(34773..35969)
                     /locus_tag="VQU30_000493"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001232144.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 8 protein"
                     /protein_id="HET2446664.1"
                     /translation="MRKSIVLAADNAYLIPLETTIKSVLYHNRDVDFYILNSDIAPEW
                     FKLLGRKMEVVNSTIRSVHIDKELFESYKTGPHINYASYFRFFATEVVESDRVLYLDS
                     DIIVTGELATLFEIDLKGYSIGAVDDVYAYEGRKSGFNAGMLLMDVAKWKEHSIVNSL
                     LELAAEQNQVVHLGDQSILNIYFEDNWLALDKTYNYMVGVDIYHLAQECERLDDNPPT
                     IVHYASHDKPWNTYSISRLRELWWVYRDLDWSEIAFQRSDLNYFERSNQSKKQVMLVT
                     WSADIKHLEYLVQRLPDWHFHLAAPCDCSEELTSLSQYTNVTVYQNVLHSRIDWLLDD
                     SIVYLDINTGGEVFNVVTRAQESGKKIFAFDITRKSMDDGLYDGIFSVERPDDLVDRM
                     KNIEIE"
     gene            complement(35978..37198)
                     /locus_tag="VQU30_000494"
     CDS             complement(35978..37198)
                     /locus_tag="VQU30_000494"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000938701.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl hydrolase family 8"
                     /protein_id="HET2446665.1"
                     /translation="MRNTKRAVAFAGDYAYIRQIETAMKSLCRHNSHLKIYLLNQDIP
                     QEWFSQIRIYLQEMGGDLIDCKLIGSQFQMNWSNKLPHINHMTFARYFIPDFVTEDKV
                     LYLDSDLIVTGDLTDLFELDLGENYLAAARSCFGAGVGFNAGVLLINNKKWGSETIRQ
                     KLIDLTEKEHENVEEGDQSILNMLFKDQYSSLEDQYNFQIGYDYGAAAFKHQFIFDIP
                     LEPLPLILHYISQDKPWNQFSVGRLREVWWEYSLMDWSVILNEWFSKSVKYPSKSQIF
                     KLQCVNLTNSWCVEKIDYLAEQLPEVHFHIVAYTNMANELLALTRFPNVTVYPNSLPM
                     LLEQIVIASDLYLDLNHDRKLEDAYEFVLKYKKPMIAFDNTCSENLSEISYEGIYPSS
                     IPKKMVAAIRSYMR"
     gene            complement(37229..39673)
                     /locus_tag="VQU30_000495"
     CDS             complement(37229..39673)
                     /locus_tag="VQU30_000495"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866442.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SP_1767 family glycosyltransferase"
                     /protein_id="HET2446666.1"
                     /translation="MIKTIVLAGDRNYIRQLETTIKSILYHNRDVKIYILNQDIMPDW
                     FRKPRKIARMLGSEIIDVKLPEQTVFQDWEKQDHISSITYTRYFIADYIQEDKVLYLD
                     SDLIVNTSLEKLFSICLEEKSLAAVKDTDGITFNAGVLLINNKKWRQEKLKERLIEQS
                     IVTMKEVEEGRFEHFNGDQTIFNQVLQDDWLELDKEFNLQVGHDVTAFYNKWENYFNE
                     LVPPSIIHFVSYRKPWTTLIANRYRDLWWEFHDLEWTKILQHHIGEFELTSSLDKEFS
                     CLTLTNSQDLEGIEELVTALPDVVFHIAAWTDMGDKLIKLAVYDNVRLHPQIVPPVLD
                     KLKKSTNLYLDINHGSADENFLKSLQEQEKTLLAFQSTQHGELGQIVFENGKVSFMID
                     TIKDFKKNGHLTCFRQLPSLTCLTFTASQDIEQLDYLAGQLPNVVFQVAAWTAMGPKL
                     YDLSNRYPNIQLYPAISRDKLDELKEKMDAYLDINLLTSTSDIVAEMAHLSKPILAFY
                     KSQNGNNGQRLYSSEHPERMLADLQKLITKDMLEKPLDIIQVKGIDETLDYIIEHNSS
                     LVRFGDGEINMLAGHSIPYQDYDEELVSIMRDIIGQESREDLVVCLPDAFTDRFRFTS
                     WAIPFWKDHMDHYMDFYRELCSDSWYGSTFVSRPYIDFEDKSQAKAQFEKLKSIWENR
                     DLLIVEGATSRSGVGNDLFDEANSIKRIICPSHSAFSRVHEIEQEIEKYAGGRLILCM
                     LGPTAKVLSYNLCQMGYQVLDVGHIDSEYEWMKMGAKTKVKFSHKHTAEYNFDQDIEF
                     IDDETYNSQIVARILN"
     gene            complement(39683..40693)
                     /locus_tag="VQU30_000496"
     CDS             complement(39683..40693)
                     /locus_tag="VQU30_000496"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar transferase"
                     /protein_id="HET2446667.1"
                     /translation="MKLHLTNLYGMAGDSTVILAQNAVQKIASQLGFREVGIYFYNIA
                     SDSPSEMNKRLDGIMASISIGDILVFQSPTWNGFEFDRLLFDKLKDMQVKIICFIHDV
                     VPLMFDSNYYLMKDYMYMYNLSDVLIVPSERMKTRLMEEGLTTKKILVQGMWDHPHDL
                     SLYTPAFKKELFFAGSLERFPDLQNWSQDTPLRVFSNKGEASSSARNLSIEGWKKDEE
                     LLLELSKGGFGLVWGTYQNDGESNQYYTLNISHKVSTYLTAGIPVIVPSSLSTAKFIV
                     DQGLGFVANSLEEVHAIVDKMNLQEYQEMTNRIKTFSYLLKEGYFTKKLLVDAIYHLG
                     VE"
     gene            complement(40722..41597)
                     /locus_tag="VQU30_000497"
     CDS             complement(40722..41597)
                     /locus_tag="VQU30_000497"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000426741.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HET2446668.1"
                     /translation="MENELISIVVPIYNVENYLRQCLDSIQKQTYPNFECIMVNDGSP
                     DHSSKICEEFVEKDSRFKYFEKANGGLSSARNLGIECSGGAYITFVDSDDWLEHDALD
                     RLYGALKKENADISIGRYNSYDETRYVYMTYVTDPDDSLEVIEGKAIMDREGVEEVRN
                     GNWTVAVLKLFKRELLQDLPFPIGKIAEDTYWTWKVLLRASRIVYLNRCVYWYRVGLS
                     DTLSNTWSEKRMYDEIGAREEKIAILASSDYDLTNHILIYKNRLQRVIAKLEEQNMQF
                     TEIYRRMMEKLSLLP"
     gene            complement(41637..42515)
                     /locus_tag="VQU30_000498"
     CDS             complement(41637..42515)
                     /locus_tag="VQU30_000498"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000739288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exopolysaccharide biosynthesis protein"
                     /protein_id="HET2446669.1"
                     /translation="MKKNHLVGDALILTVSDQIEELDYLLESLPNICFYIAAPVQFSE
                     KIRSLETNYNVRLRTITNEEQLNFLVDTCDFLLDINHFQEVDAIVSKFVQAGKSVFAF
                     DNTVHGNQGQEVFLSSTPDKLVSRVRDYLNEVRVGTNHQEKIIQDGTWNVFKIDDKAH
                     FIVGANVICRNFENFHVSSGKLILHDGVFINNSCSFNCMERIEIGAGTMMGEGVRFYD
                     HDHIYTAEKIEKWQWTTAPIRVGRDCWIGSNVTILKGVTIGDNTIIGAGCLIRNDIPS
                     NSVVYNNGNLVVKRRD"
     gene            complement(42512..44597)
                     /locus_tag="VQU30_000499"
                     /pseudo
     CDS             complement(42512..44597)
                     /locus_tag="VQU30_000499"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000341103.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
     gene            complement(44658..>45779)
                     /locus_tag="VQU30_000500"
     CDS             complement(44658..>45779)
                     /locus_tag="VQU30_000500"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015898732.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HET2446670.1"
                     /translation="STSASASASTSASESASTSASTSASASASTSASASASTSASTST
                     STSASTSASTSASTSASTSASTSASESASTSASTSASTSASASASISASESASTSASA
                     SASTSASASASTSASESASTSASASASTSTSASESASTSASASASTSASASASTSASA
                     SASTSASESASTSTSASESASTSASASASTSASASASTSASASASTSASASASTSASA
                     SASTSASASASTSASASASTSASASASTSASASASTSASASASTSASASASTSASASA
                     STSASASASTSASESASTSASESASTSASASASTSVSNSANHSNSQVGNASGSTGKSQ
                     KELPNTGTESSIGSVLLGVLAAVTGIGLVAKRRKRDEEE"
BASE COUNT        13345 a        10284 c         8208 g        13942 t
ORIGIN      
        1 agggcgattg atttttactt ccgtcgcatc aatcattacc gtgtcttcag aactgagagg
       61 agttcttgaa atcgtaacac cacctttgaa caagagttac ttcaacccat tggctccgac
      121 ggagtaagtt gctttcgtgg ataccaaaat cagccgcaat ttcttcataa gtgcggtatt
      181 ctcgcacata tagaaagcgt tgttaattta tttatctcat ttttcagaaa attcttttat
      241 ttctgtaaag tctacgatac tcgatgtgtt tttatataat gatacagtct gagaatcact
      301 gttccgctag ccattccaat agagattacc aaagccaaca tgacaaccaa ggtcgcactt
      361 gccagtgctt tattatagtc ccctgtcaca aaaaaggcag ttgttcggta ggagagataa
      421 cctggaacca gcggtgccaa aatggccaag ataaagacca cagcaggtgt cttataaaga
      481 atacttaaaa tctggctgac acaagaacca ataatggctg caatgaaggt agctacaatg
      541 acattggtcg gttccttgag caagagatag attagccaga cagtcatgcc caaaatccct
      601 ccaggtaaga gcatagaccg ttgcacattg agtacgatta aaaaagtgat aatggcaaga
      661 aaacttgcta ctgcttgtaa taaaaaggtt gttagtgtca tattagttca tcaataccaa
      721 ggcgacagaa gttcctgccc ctaaagcgag ggtaatgagc agggattcaa acatcttact
      781 cataccagag tttatgtggt tggtcataat atcacggacc gcattggtca aggcaatacc
      841 tggtacaaac ggcatgaccg caccagctat aatcaaatct gccgttgaag gaaaacctgt
      901 gtagcgagcc caaaactggg caattatccc aaagacaaag gctccagcaa aggctgtcac
      961 aaagggaatt cggataaatt tttccacata gagggaaaag gcaaaaccaa ataaggtcgc
     1021 cactcctgcc ccaagtgcgt cgtagatatt tccgctaaac ataactgaaa agaaaggagc
     1081 actaaaggtc gcagccagag ttacctgcaa cttagtatag ggaaggggtt gagcttgcaa
     1141 ggccgtcaat tgcttaaagg ctgtttctaa gtcaatctgc cccccaacta gctgacgaga
     1201 aatctggttc acatcgcaga ctttttcgat gttataagaa gaggaggtca cgcgcttcat
     1261 gcgcgaaata ttggtatttt caatagagaa aaagatagcg gcaggcatgg caaggacatt
     1321 gcaatccaca atcccctgcg aatgcgcgat tcgaatcatg gtatcttcta cacgatggat
     1381 ttctgagcca cttttaagga gaatagtccc cgctagcata atcacatcaa tgacggcatt
     1441 taattctttt gattcttcca tgctttcctc cttttatcaa ctccctctat tctatcacaa
     1501 atccggactc aaaaaaaatc tttgccatga aatcatgaca aagattgatt actcattttg
     1561 attatccatc tgcttttaag gagtagctga agttgtttta ggtttgtaga ttgaaatctt
     1621 gactctagtc ttattgaggt ctaccttttc acctgctcta ggactttgtt caacaaccat
     1681 gccttctaca ctacctgcag gcgctgtcgt cacttctaca acttctatat tagcttcctt
     1741 aatcccaaca atttgaatca aattgttctt agtaaactcc aagctggaac caatgtaact
     1801 cggcatggca acacttgtaa cttttttagc tactgtcaag acaatttgag taggtttact
     1861 cacatcataa gtcgttccgg cacctggact ttgtttcata atcgttcctg gttcgctttc
     1921 gctggactct tcttcctcta tcttaatcaa attctcagga accttcttct gcttgagttc
     1981 tgagattact tctgtagagt tccgtccaat atagttccct aattgaatcg tcgtagcttt
     2041 tttagctact gtcaaaacaa tttgagttgc cttgctcaag tcataggtcg taccttctgg
     2101 tagactttgc ttcaggaccg ttccagcctc actctcattc gactcttctt cctcaatttt
     2161 aatcaaatta tctggaactt ttttctcttt taattccgcg ataacatcag aagatttccg
     2221 gccgacataa ttactaattt ggaaggattg tttgcctgat gagacaacca gattgatttt
     2281 cgttccttct tttcgaccag ttccagcgcc aggatctgta cggataatcc gcccttcttc
     2341 caccttttca ctagcctctg tcttctcctc accaatctca aaattggctt ttttgagcgt
     2401 tgccttggcc tctgcaactg tctgacctgc cacatctgga atggcaatgg ttgcaggagt
     2461 tctggatagt atccaaataa gagaagctgc caccaataca aggctggcca acaaaatcag
     2521 gtaacgcatc ttaaatctat gttttttcgg tgcttgtggt tggtaagttt cctctgtcac
     2581 agcctggctt gggtttttga ttgatttgtg ttctgtctgc gcttgaacct taggaataga
     2641 tgtcaaggta ctctgagaaa ccttcggcaa ggtcttggta tctgccttgc tcgtttcatc
     2701 aaagattaac ttactttcat ttctacgatt gtaggacaag ctactagaca agtccacata
     2761 catctctgaa accgagcggt agcgattggt caacttttta gcagttgcct tgataataac
     2821 attttctaaa gcctgaggta cagatggatt ttctgcaata acggacggca ggggtttctg
     2881 gaaatgctgg agggcaatgg tcaccgcgct atccccgtca taagggatat ggcctgtcaa
     2941 catctcatag aaaataatcc ccatggcata gatatcactc tgcacagtcg ccttcgaacc
     3001 acgcgcctgc tctggtgaca agtaatgaac tgagcccaac atcgagttag tctgggtcag
     3061 acttgtctct gcaaaggcta cagcaatccc aaagtctgtg accttggcag tcccatctgg
     3121 tgtcaaaagg atattttgag gtttcaagtc cctgtgaaca attcctcgag tatgggccaa
     3181 gcgcatagcc aagagaattt gtcccatgat acggactgct tcttcattag aaagaggata
     3241 atgttccttg atatagcgtt tgaggtccag tccagccaca tactccatag ctaggtactg
     3301 ttgaccgtct tcctcgccaa tatctgttat ccgaacgata tgaggatggt ctagatctgc
     3361 catagctctc gcttcacgct gaaaacgagc tacagctatc gggtccgtct ggtagttggt
     3421 cctcagaacc ttcactgcca cttcttcccc atctaagatt aagtctttgg ctaggtagac
     3481 atccgccatg cctcctcgac caatctgttt gacaatccga tagcgtccgg caaaaatctt
     3541 gccgatttgg atcattctgc atcctcctcg ttcataaaaa caagggcaac cgtaatgttg
     3601 tctaaacctc ctgcattgtt agcaaaacga acaagtgtct ccgttttatc tgctaaagga
     3661 atatcactgg ttacaatatc acgaatctca ctgcctgaaa tcatgttggt caagccgtca
     3721 ctattgagca agagatagtc acctgactca aggataactg tcccaaaatc aggctgaatt
     3781 tcatcttttt gcccaataga ctgggtgata atattttttt gcggatgagc ttctgcctct
     3841 tctggtgtca attgaccagc cttgagcaat tcattaacca aggaatgatc gctcgtcaac
     3901 tgatggtatt cttctccacg aatcaagccg atacgcgaat caccaatatg agcatagata
     3961 gcctgattat caataatagc aaggacttcc aaagtagttc ccatgcctct gtaagcttca
     4021 tcctgaccaa gctggtgaat cttttgattt tcaatttcta ggtaatgggc gaaccattca
     4081 cgcacttcat tgactgtatc gatctgggta tcaacccaag ctacacccag gtctgtgacc
     4141 gccatttcac tagcgatatt ccctgcacga tgacctccca tcccatcagc taaaataatc
     4201 atggtacgtc cagctctatt gacatagtgg ttgacatagt cttggttatt tgttcgtttc
     4261 tgaccaacat ctgttaataa tgaaatttcc atgtgtcagt tccttcctaa tccgatatct
     4321 tgcgaaattg actgatgaag aatccatcac ttccatacaa ttcaggtgta atgaggatac
     4381 agccgtcttt catgatatcc ttacattcat gttctagttt tacctgctcg aactcgggat
     4441 gactctctaa aaaggcctta acgacttgaa aattctcctc tgagacgata gtgcaggtgc
     4501 tataagttat tataccacct ttgcctagta tttgacaaac actacctaat atttctaact
     4561 gaatttcctg caaggacgcg aaatctgccg tttctttatt gtatttgata tctggttttc
     4621 ggcgcaaaag accgattcct gaacaaggag catccaccaa aatcttatca aaggaatcct
     4681 ggtcaaaaaa ctcatgcacc tttctggcat ccaatttttg agtttgaacc cgatcttcaa
     4741 ctcccagacg ttgggcattt tcttgaatta aatccaactt gtggtcgtac aagtccagag
     4801 cagtaacctg acctgtcgta agataagagg ctatatgggc tgttttccca cctggagccg
     4861 cacaggcatc aagcactcgc tcatcacctt gtaaatcaag cgtcggagca accaactgac
     4921 tggactcgtc ttggatggta atggctccat ccgcaaacaa attatgccct gcaaaatgcc
     4981 cctgctcctt aaccagacca gtggttgcta aaagggaatt attcgcctcc aacaaggctt
     5041 ggatttcctc ttttcgactt aggtctgtta cacgaatact ggctttgttt cgcactaaca
     5101 ggctttcaaa gatggctttt gctctctcct ctccgtattc ttccttgagt ttggcaacta
     5161 gccaaactgg gagagaatag gcaatggagt cacgcttgtt ttttcgcttg atgctagcaa
     5221 tatctggcca gccttcacgc aagatacggc gaaggacagc gttgaccaat ttttcactgc
     5281 cttttttacg gagtttggcc aattccactg cttcattgac cacagcatga tctggaatct
     5341 tgtccaaata gcggagttgg taggcactca tgagaagaag gacatagagc cagctgtcta
     5401 actggtctct gtcttcgata aagtgggata ggtaccattc cagagtcagt ttacgggcta
     5461 ccgttccata gactagctcg gtcactaagc ccttgtctgc tgcagagagc tgactcccct
     5521 tgaggtgttt atttaaggca atatttgaat atgcttgatt cacaaaaaca tcctctagca
     5581 ctgctagagc taaacttcta gccgtttcta ctttagtcac caaatcgttc tcctacagtc
     5641 aatgtacgtc caactccatt gaggaaggaa gcaatgtcca tcttaggctt accagctggc
     5701 tgcacttgtt tgagggatag agccccttca gccgttgcga caatcaattc tttcttgccg
     5761 atagagagaa tctcacctgg atttccctga ccttctactg gtagggcttc ataaatctta
     5821 aagcggtcgc ccttaaggaa agtatgggca acaggccagg ggttcattcc acgaatttgg
     5881 ttaaagagtt gacgattggt tttgttccag tccagttttt cttcctctgg ctttatattt
     5941 ggagagaagg taacctgact cgtatcctgc ggttcaggtt tgatatcacc agcaatatag
     6001 gcaggcagag tgtccaaaag caaatcacga ccaactagcg ccaatttttc aaacaaggtg
     6061 ccaacattgt cctcatctgt gatcggaatg ctgcgacgag aaatcatatc tcctgcatcc
     6121 atttccttaa ccatttccat gatggtcaca ccagcttcct catccccttg aatcaaggca
     6181 taatggatag gcgcaccacc acggtgtcta ggaaggaggg aggcatgaac gttgacagca
     6241 aagtccatgc tatcaaggag tttgcttggg agaaactgcc caaaagcagc agtcacaatt
     6301 ccatctgctc ctagcttcat aagttcttcc atctctggac ttccagataa tttttcaggt
     6361 tggtagatag atagtcctgc ttccttggca gcctgcttga ctggggtttc ttggataact
     6421 tttttacgac caacagcacg gtctggctgg gtcacaacgg ctagaatttc gtaacggtca
     6481 tctgtcaaaa gtccttttaa gactgttgct gaaaagtcgg gggtccccat aaagattagt
     6541 tttgtcatat cttctccttc ttataaaaat tgctgcggct catggtcaat gctgagacgg
     6601 agctcactat tttcccgttc ttgagtcaag gccaagacct ggttgagggt cggccccagc
     6661 tcatcttcta aacggtattt aattaaaatc tggtaatgat agaggttgtg ggtacgggca
     6721 atcggttttg gcgttggccc cagaatggga ctggtctctg acaagcctga ccgcaaaatg
     6781 ttcatgactt cataggcacg tttgaaaacc tcttcttctt tcttgtgaga aagggtaata
     6841 ccaatcgtga aatagtaagg tggatagccg agttgtcgtc tgattcccat ttcataggca
     6901 taaaagcctt cgtaatcttg atccttggca aatcgaatag catagtgctg cgaattgtag
     6961 gactgtatca agacttgacc tgctttttca gcccgacctg ctcgacctgc cacctgagtc
     7021 aagagctgga aggttctctc agaagaacgg aaatcaggca gattcaaggc cgtatccgca
     7081 tttagaactc cgactagggt aacattggga aaatccaaac cctttgcaat catctgagta
     7141 ccaagtaaaa tatccgcttc ccctcgccca aactggtcaa gcaaggcttg gtgactgcct
     7201 ttctttcgag tcgtatccac atccatcctc aaaatgcgag cttggggaaa gagttctgct
     7261 agctcatcat aagccttctg agttcccgtc ccatagtaac gaatactgcg gctcttacag
     7321 ttaggacaga cctgaggaat atccttcgag aaaccacaat aatggcagtt catagtcttg
     7381 gtatccatat gcaaggtcag agaaatatcg cagttgggac aagtatccac cgtcccacac
     7441 tcccgacaca tgacaaagct agaataacca cggcgattga gcatgagaac cacctgctct
     7501 tttttaacca gacggtcttg gatagcctct agcaaaggag gcgtaaagtt tgacgtctca
     7561 ttttgtccga tatagtctcg aaagtcaatc acttgaacct cagggattgt agccaaagga
     7621 ttggcacgtt gggttagacg taagtgttga tagacgcctt tgccagcacg tgcccggctc
     7681 tctaagctcg gcgttgcaga tccaagtacc agagttgctt gattatactg agcccgtaaa
     7741 atagctacct ctctggcatg gtaacgggga ttgctgtcct gcttataagc cgcttcatgc
     7801 tcttcatcaa taatcatgac acccagattt ttcagaggag caaagatagc agatctggca
     7861 ccaacaacaa cttgggcatc gccacgctcc accttgcgcc attcatcata cttttcgcca
     7921 ttggataatc ctgagtgaag aatggctacc ttgtccccaa aacgtgctat aaaacgctcg
     7981 gtcatctgag gagtcaagga aatctcaggt accagcaaaa tagctgtctt acccttatcc
     8041 agggcacctt ggataatctg caagtaaacc tcggtcttcc cacttcctgt aatcccttga
     8101 agtagaaagg gaggttgaga actgccaata gaactcacaa ccgcatcacg cgcctgtctt
     8161 tgttctggat ttaactccaa aggtctactt gcttcaattc cttcaaaata agcagccgag
     8221 cgttgaactt ccttttggac tatggtaaca gtaccttgat ccacaaagaa gttgacttgc
     8281 tctcgcgagt aggactctaa caagctagcc aaggaagcgc tctctggatg agacagcaga
     8341 taatctctca gttccaactt tttcttggca cgtgtagaaa tctcaacacc ttctaattgg
     8401 gcatggtcaa cctcatacca agactgggtc ttgaccttct tttgatcgac tgcctgatat
     8461 tccagaccaa gcaggccttt tctagtcaaa cgcatcattt cagcttgctt ggcaaggtct
     8521 agtgaagaaa aggctagcga atcttctgaa ccaaacaggc gtactcgttc ttcctgactc
     8581 aagccttcca gaggatagag aatcttgtca tagctagaat tcagaaaccc tggaagcatg
     8641 gccttgagga tagagatttt gtaggagaag acagatttgc gtaactcctc agccagccag
     8701 agttgttctg gcgtgagaac aggagaaaaa tccagcacct ctgcaatatc ttttaaatct
     8761 tgctccatct cttctccatc tgattgggac ttcaaaccaa gaacaatccc ttgaatcagg
     8821 cgattaccct taccaaaagg cacatgaacc cgcatcccaa cttccagcat tccctcaaat
     8881 tcctccggaa tcctgtaact atagggctgg tccgtctgca tcaagggcac atctacgata
     8941 atcttagcta gggccatctt ctcacctcct ccttgtcagt acattcttgc aatagaaaaa
     9001 ataagattga gtccccccaa ccttaaattt tttcaccatc ttctttttct ttagcaattt
     9061 gctctttgat tttcttttct tcttcttctt tgcggcgttt ttcttcttcg atacggcgac
     9121 gcactgcttc acgttttcct tctggatctg ggtgaattgt aacgtttcct gattcgattt
     9181 cttctaaagc gcgaagagtt gatttttcag acttgaaacc ttgagttgct ggggcacctg
     9241 cttccaattc gtgggcacgt tttgcttcca agattacgag tgaatatttt gaaggaacct
     9301 tgtcgagcaa ggtatcaata gagggtttta acatcatttg cttgtaccta ttttctaaat
     9361 tttatcgggt agttggagat tttggtaaca tctcctgata gtgaccaatg acacgatcca
     9421 cacagaagtg ttctgcttca atcacacatt tgacacgttc agcagctagg ggcacctgat
     9481 cgttgacaat cgcataatca tactcacgca tgagggcaat ttcttccttg gccttttcga
     9541 ttcgttgggc aatcacttct gcactatctg ttccacgacc taccaagcga tcttgcaatt
     9601 catccaaatc tggtggtgtc aggaagataa agacagcatc tggaaccttt ttcttgacct
     9661 gaagagcacc ctgaacttca atttcaagga aaacatcgat tcccttgtcc aaggtttcat
     9721 tgacataggt cagaggagtt ccatagtagt tgccgacata ttctgcgtat tccaacatct
     9781 gtccttgacg aatcagctct tcaaattctt cacgagtacg gaagaaatag tcaacaccgt
     9841 ccacttctcc aggacgttgt gcgcgtgtcg tcatcgatac agaatattga aattggtttt
     9901 cagaactctc aaaaatctct cttctaaccg ttccttttcc aacccctgaa ggaccagaaa
     9961 aaacgattag taagcctcgg tctgccattg tgtctccttt tagtcaatct gtgaaataac
    10021 atttctctag aataatggca aaaagccaga ttatccttta cagtctttct atctagtgta
    10081 acaaaaaagc agtaattttt caactgctct ttcttattta tttagcataa tctactgcac
    10141 gaagctcgcg aatcacggtt accttgatat ttcctggata atcgagattg ttttcaattt
    10201 tcttacgaac tttgtgagcc aagattgtga ctttgtcgtc cttgattttt cctggattga
    10261 ccatgatacg aatttcacgt cctgcttgaa gggcaaagct agtttgcact ccttcaaagc
    10321 cgttagcaat ttcttccaaa tcatggagac gcttgatgta gctttcaaga gactcactac
    10381 gagcacctgg acgggctgcg ctcaaggcat ctgctgcagc gacgataact gctatcacgc
    10441 tctcagcttc aacatctccg tggtgactag caatcgtatt caccacaact gggggttcct
    10501 tgtacttacg ggccaattcc ataccgattt caacgtggct accttcaacc tcatggtcaa
    10561 tggctttccc gatatcgtga aggaatccag cacgacgggc aagagccgca ttttcaccaa
    10621 gttcgctcgc catgatacca gccaacttag caacctcaat cgaatggcgc aaaacatttt
    10681 gtccatatga agtacggaac tgcaaacgtc ccataatctt catcaagtct ggatgaaggt
    10741 ttggcgcacc aatttcatag gcagcagcct caccgtattc acgaatctta ttgtcaatct
    10801 cttgacggtt tttctcaacc aactcttcga tacgagctgg atgtatacga ccatctttga
    10861 gcaacatttc catagtcata cgggcaatct cacgacgaat cggatcaaat cctgacaagg
    10921 tcaccacttc tggtgtatcg tcgataatca catcgacccc tgtcaaactt tcaaaggtac
    10981 gaatgttacg accttcacga ccaataatgc gtcccttcat agtatcgtct ggcagatgaa
    11041 ctgttgagtt tgttgactcc gctacatatt caccagcgat acgttgcata gcttgaacca
    11101 agatgtcctt ggccattttg tcagaacgtt ccttgacctc ttgctcagct tcgcgaatgc
    11161 gactggcaat ctccctggtc aagttttcct ctgtctgagc caagataata tctcgtgctt
    11221 ctgcctgaga cagagcacca atacgctcta gttctgcttc tttttgtctt tcgacttcct
    11281 ctaattgctc ttcacgcgca tcaaggtttt tcgctctatc agaaatactt tgttcttttt
    11341 gttcaagtgt ttgttcttta ctcgtcaaat tgtcgtcctt acggtcaagg ctagtagctc
    11401 tctctgtcaa acgactttcg atttgtttga gttcttgacg ttctgatttg aattcagcgt
    11461 ccacttcttc acggtatttt ctggcttctt ctttggcctc caatagtgct tcttttttaa
    11521 gagacttgct ttcacgtttg gcttcattaa caagtaaatc cgcttcacgc tcagcttgtc
    11581 cacgtaaatt agttgcttct tgttcagcat ttaaaagcat caactctgca gcttcctgag
    11641 atgatttcat cttagctgag atgctgacat atccaatgac taaaccaatg atgacggcaa
    11701 aaacagcaat cgcaagcgac atgatttcca tgtttttacc tcattttatt gttattccga
    11761 atgacataca ttcttttaca ttctaccata aaaaagtgat tttcacaaac ctaaaataga
    11821 atatgttttg gggaatttgg aacacattta ccaaaataaa cttgttgttt agaaatagta
    11881 gtttagtaga gacttgagaa aaagcctact ttgcagtaga cttagtaatg atctttaaag
    11941 gacaagaaag ccacgctatc tccatccatc atataaatca agcgattttc tgcatcaata
    12001 cgccgtgacc aggctccttg gtaatcatat ttgagtggct ctggttttcc tattcctgta
    12061 aatggatcgc gttgaatatc cttgattaat ttattgattc tttttagtgt ttttttatct
    12121 tggttttgtc agtagcaata atctgcccag gcatcttctg taaacttgag tagcattcat
    12181 cactcctcaa tcacatggac ctgagtgctt ccagcacgga cttgagccat tcctcgcaaa
    12241 accttgtctg ataactcctt attttgggcg attctcaggg tttcctgaat actgtcccat
    12301 tcgctctttg aaagaactac aatgtcctca tctggatttt tattgaccac cgtcaaaggc
    12361 tcaaattcat catttacctt cttcatgtag tcctttaaat gatttcggaa tgttgagtaa
    12421 aggactgctt ccataaccat acctcgtttt agctcttttc cactattata cacgaaaaga
    12481 aagaaattgt caggaacttg tacaagattt tcttttctat ctatttatac tcaatgaaaa
    12541 tcaaagagca aactaggaaa ctagccgcag gctgtacttg agtacggcaa ggcgacgttg
    12601 acgcgatttg aatttgattt tcgaagagta ttattcgtaa aaaatctcaa aaagcctacc
    12661 tttcggtaga cttagtttgt ttctattcta atcggcactc ttccaaaatt ttgctctgct
    12721 atacttggct tccctagttg gtaaatctgg tctgcttttt gggtcatagc atcccaaggt
    12781 tctttgccaa ttcggctgac tagattgacc tgtcctttca gagacttgag atgttgcctg
    12841 actttttcag taaatccaag gacatgaatg gcttctggca agacattttc tctagcctgt
    12901 accaaaatat aggtcaatag gcgtctgaca cgcgccttgg tgtaacgttt ggtagtcact
    12961 aactcgacca attcttccac agactgggct gttttaatag cttctttaat gcgcacagcc
    13021 atttcttgat tgacctgata gatggtggtt aggtcgggat ttgacaagat ttgatagcgg
    13081 agcaagggaa aatagtcttc ccagatcacc ttactggcct gctcaaatag ggcaacagaa
    13141 ggcataaaac gttctaagaa atcttggtcc ttctgatgtt gacggagggc tgtcgccgag
    13201 gcaaagtcca catctttatt cacagaatgg taacctgccc cctgacgctg aatcggatgc
    13261 agcttgatat ttcgtcctgc aaccgccttg gcataggcca gagcaagaac atgattgggg
    13321 gtattacctg aaaaatcaag accagcaaat tccttccaca tagcttgggt tttctgggga
    13381 taggaaaggg aatcaggcag atttttcaca aatttctcca tctcagcacc tttctctgtg
    13441 tataagtcag cgattttctg gtaatccaga acttcctctg tcccaaaaac tagactatca
    13501 atgcccaagc gatccaagat atccacagct ccttgaccaa agaaatcagc tgcctgaaca
    13561 ctgactaaaa agggcaattc cactaccaag tctgcgccat tttccagcgc catctgggcc
    13621 cttgtccact tatccacaat agcaggctct ccacgctgca tgaaattccc tgacatggca
    13681 acaattttca gtccctctgc ctgatccagc aggtatttat ggccattatg aaaaggattg
    13741 aactccgcga taatacctgt tatggtcatg ctaatctcct acttctgcgc cacaaaaaac
    13801 caacgggtgc tagtttctgt tggctcctta tcctcaaagt ctgcatagag tttgaaggac
    13861 ttaaatccag cctgttccag caagatatca taggtcaaga tctcataggt cctctcctca
    13921 tgtacttcat cgtggcgact aaaggaaccg tcagcctcct tgataaagaa agtcagctca
    13981 tgcacgatgg agtgaggaac ttcgtcctca tatgtatccc aaagcatggc aaaatcttcc
    14041 gcattttcat ggtaggaata gccagggaat acttcatctg tctggtaggt cgagtgcacg
    14101 tcaaagatga aaactccctc ttcattcagc gcattgtaca cgtccttaaa gacgtcccct
    14161 acttccacct catcctgcat atagcagata gagtccgaat aacacgtgac aaaatcgtat
    14221 ttccctgcct tggacaaatt cagcatatta ccttctataa aagcaatctt ttgcttggct
    14281 gaagttgctc tcttctccgc aatcttcaac atatccgcac tcaagtcaag tccagtcaca
    14341 tcaaaaccag cctgagaaaa gcgcactgat tgaattcctg tcccacaagc caattccaag
    14401 agtttctttc tctccttggt cttaggcaaa tgacgcagag aaaaattcgt ccatttgtcg
    14461 tataaactat cgtccatgac cgcatcatag accgccgcaa aggtttcata agtcgccata
    14521 aaacatgata ccaagtccgc ccgtaattcg atagaaaatt aggagcctta cgatggagcc
    14581 gagctccaag gaaggctatc tattttccga gaattacagg acgggttcaa atcctttcta
    14641 agatacaaag agccttaaaa gcaaagagta cataggaaac tttcttccct atcgtcagat
    14701 acaaagaaag ttacttttta tctcagcttt tagctcgtgt tcagtttcga aatgaaacaa
    14761 acacgaggcc ctttaccttt ctatcaattt ttctaaaata agcaaagaaa cccagttgac
    14821 tacaactgag ttcatcttct aagcaagagc ttctgaaata tctactgaat tcgcctcatg
    14881 ccatagcttc tctagattat aatgggcacg catttcttct gaaaagatat gcacgacaac
    14941 agcaccaagg tccagtaaga cccagcctcc agctgcatcg ccttcgacat ggctaccttt
    15001 aaagcctgct tgagctactt tttcacggat attagctgcg atagcgtcca actgacggct
    15061 attcattgag ctagtgatga caaagtagtc cgtcacacta gtcaaatctt gtacatcaag
    15121 tgcgaggata tcctccgcac gtttctcatc agccgctttc acgactagtt ctagtaattc
    15181 tttttcgttc atttaatcct ctttttagaa aatatgtttg taatctagaa catctgcaaa
    15241 gcgctcctcc caaatgtcct cataaaattc attaatcgtt tctgctggaa tgtcatcccc
    15301 atcaaaggtt gtgacagcac cttctggaac aataagctga tagccatatt caaaggcaac
    15361 cttgacagag gtatccacac aatattctgt ctgcatacca cataaaacta atttttcaat
    15421 cccctgctta tccaagtatt cttttaagcc agtttctttg aaaatactgt tatacttctt
    15481 ctgaaagacc ttttcagcag gttttcgatt taaaagcgca gataactgcc aatcttctga
    15541 tgtttgagct tcagagttct caatatgttg aacatagata atttcaatat tcttgcttct
    15601 agcctggttt tgtaaataag aaatttttcc caatagactt tttgtctgga acccagtttc
    15661 tactaaaata ttctgaacat caatgattat aaaagccgtc ttcatttagt tctctttcaa
    15721 atagtgcaca aaggcgttat aggtttcaag ggtttgggga tagatgggga atccctgatg
    15781 agctagatac tccacggtac gagctgtttc gtaggccacc gccttattga gcgatagatt
    15841 tgcaatctca cgcgccacat ctactccagg aaaggctcga ttgtgctcga tatagtctgc
    15901 gacgtagatg accttatcta ggtctgtcat ttgaccagca ccgactgtat ggacttcaat
    15961 ggctcgcagg atttctgaat catgcaaatc caaatcttcc tgaattttgt aaattccgac
    16021 cataccatgc cagacattat tgccccagtt tttgaggtca gggtctagct ggtaacggtc
    16081 aatcaaggct agaaattcct gatttgacaa ctttttagca tagtcatgaa gaagacctgc
    16141 tagacttgct ttctcaacat ctacaccaaa gcgctgagct aattccatag cggcacgctc
    16201 cacacctaga caatgggtta gacgtttctc aggtagaaac tctgccattt tttccaacaa
    16261 ggcctcacgg gagcagttga tatagtcttg ataggacatc agtagagccc ctccttctcg
    16321 atgtagtcta gcactggctg aggtaggaga aagttgggtt tccgaccttg ggcaaggaag
    16381 tcccgcacca tgctggacga gatatccatg agcggtacgt ccacccagat aactggatag
    16441 gaagtcccta ccttgtagcg tggacgctga acccccacaa actgaaccat gtcaaccagt
    16501 tcatcaattc ggtaccactt aggcagatag tcaaccatgt cggcaccgat gataaagtaa
    16561 taatccgtat ctggattctt ctctgtcaaa atcttcatgg tgtcgtaggt gtaggaaata
    16621 cccttgcgct ccaactcaat ggtttcaatg actaggccgt caattccctc aattgccaac
    16681 tcaagcatct tgagacgatg gtgttcaggg atggtttcct ttttatcaac gtgaggaggt
    16741 tggtattcag gcatgagaag aacttgatcc agtcccaact gttgccgtac ttgatccgca
    16801 acaatgagat gggcattgtg aacagggtta aaattccccc ctaaaatccc aacttgtttg
    16861 cgttttttct ccttgatttc tggctccaac tctaccttgg taaagggagt caatagttcg
    16921 attgtcatag gctagtcccc tttatttctc tataaaaaca gttatttgga gtttcggtct
    16981 tagatttctt tgactttctt agaaatcttg cgattttctt tcttgctaga ttgcttaaac
    17041 aaaatcaaga tgcgtcctat tttttggact gtatccacac cgatttcttc ttccaaaatt
    17101 tcagctactt cgtggatgtt ttcatctgtg ttttgtaaga gagtaacctt gattaattca
    17161 cgcgcatcaa gagcttgacg gacgctggtt ttgatttggt cgttgagtcc atttttcccg
    17221 atttggatga taggtttgag ggtgtgtgcc tggctgttga ggaaggcacg ttgttttgat
    17281 gctaatgaca taattttctt ccttgttttt tgatagttat tttaggtggt gagggacggt
    17341 cggaactaat tttccaaaga tttcatcttt gaaaaatgga tttcctgacc tcacaattga
    17401 gccttggtct caattgtgcc ccttgccaat ctacagattg gcaatcacac cacggcaata
    17461 actatcgcta tatgagctca ctttgttcgc tcagcgattt tgttttaaat aattgctttt
    17521 cgtgtggcga cggcgacgcc ttctggtgcc cagacggcga cttttgctgt gcctgttaca
    17581 cgaatccagc ctaggcctga aatgactagg tctgtcttat ctttaatggt aaagacatgc
    17641 tggactagcc ttgggaaatc ttctttttcc ttgctatttg gtggtgtcag aagagttccc
    17701 aggtgcttat cgtagaaagc actagctcct tcaagcttgc tacgatggag tttgagttca
    17761 ttatcaaaga aagcagtaaa tccttgcttt tctcctgcta taaagtcaaa gcgtcccaaa
    17821 ccacctaaaa atagggtttg ctcaggatta agctgatagg tcttaggctt gatttccttt
    17881 ttaggactga catacttgag gtttttggcc gtcaagtagt gagccatctg gtggcggtgg
    17941 ataattcccg gcgtatcgta aatataagat ccgtcgtcaa gcggaatctc tattttgtcc
    18001 aaggttgtcc ctgggaagcg tgaagtagtg atgacattct gatcacccgt gatttcttgg
    18061 ataatagcat tgattagagt tgattttcca acgttggtca caccgaccac atagacatcg
    18121 cggcccttac ggtagtgttc aatcttatca atgacttcct taatggcatg tttattttgt
    18181 gctgaagtta ggaccacatc gactggacga agaccttctt catgggcacg tttcatgagc
    18241 cactggctaa tcttaccaga cttaactgac ttaggaagga tatctttttt atttcctacc
    18301 aagaggacat cattgcccga gacgaaacgt ggtaaacctg ggatgacaga tccattaaaa
    18361 tcaaagatat caatgacatt gaccactaag gcatcactgt ctcccacctc gtgcaagagc
    18421 ttgaggaaat catcgttcgt caactggaca tctgtgattt cattgtagtg gcggagacgg
    18481 aaacagcgtt ggcaatagac ttcgccagtc tccaaacctt tttcaagtgc cgactggggg
    18541 gtaaaaccaa gaccagcttt atctgtcgtc tgaatggttg ctccacaacc aatacagaga
    18601 atttcttcca tagttaaatt ccttttttat atgtaatcgg tccgtacttt tcagtgattt
    18661 ttctcataac acgacgctca cgagttcggt taatctgcgt tttgattgag tcatgttgga
    18721 ccaagggttt gactaaaatt gaccgaatcc ctgcacggtg ggctgctcgt atatctgtca
    18781 tgagctggtc gccaaccatg accacttcct ttttgtcata gtggaattcc ttcatggcac
    18841 ggtcaatacc aaatgtgaag ggcttcaagg cccagtaaac gtaatcaatc ccaaatttct
    18901 caactgctcg ttgaacgcgt tttttggtgt tatttgacac tacgataatg ccaatacccg
    18961 cgtcccgaag gtcatgtagc cattgcttca tctctggcgt tccatcaggg ttgttccaag
    19021 caatgagggt attatccaaa tcgaccaaaa cagccttgat tccctgcgcc tgcaggcttg
    19081 ggactgtcag atcatagact gcttccacag caaaatctgg tatataattt tcaatcgcca
    19141 ttctggctcc ttttcttaac tttttttcgc aattttcctt agtaacaagg ataaaacaat
    19201 ccacaaacct gcactagcca aactgatata gagccaagca tggggctcat ctgttaaagg
    19261 taagggaaca ttcattccga aaaagcctgt cacgactgcc aaaacagcta gcaagactga
    19321 aatgatagtc aaggttgtca aattgtcatt cagattattg tttagaatat tgttgtaaga
    19381 ggctgaaagc tgctgtaaaa tctgagagat taggtctgtc atggatacca gctgatgagc
    19441 ctcaatcatg gcatcatcaa actgttctct ctcaatctca tcaaaactac gatacaaggc
    19501 atgaccttga atatgctcta acaaaatccg attttgtttg gcagctgccg tcagataaac
    19561 cataccagtc tccaaatcag acagggcaaa gaggtttttc ttggtagttc gctggcgcaa
    19621 gaggtcattg acctcatccc tactcttgtc catctgctca atgacaggat agtaggcatt
    19681 gctgatgatt tccagactgg caaagagaaa cttataaatc gaaagcgtgt catggctctc
    19741 cagataacga gtcatctgtt caatgacata ggcgttcttg gtattactaa tggtaatcag
    19801 gcgacgatgc tcgacgataa aggtcatggg aaaagtctca tagtaggcct tgtccttttt
    19861 tacgtctagg acattataga taaaggtaac cgtcccactt tcacggtggt agtccatgtg
    19921 ggcgcgctcg tttctatcca gtgcgtattc aatggtttcc ttgtccaaac cgtaaatttc
    19981 agaaaggtct tctagtttat tcaactttcc taggtctagg tctatccagg tacaaccatg
    20041 gcccaactgc ttttctaaaa ccatcttttc tccttattaa actccctcta ttgtaccaca
    20101 aattacttaa aataacaggt ctagtctgtg cgtgagaaat tgctaacaac tgtgatattt
    20161 cggttaggga caaagtgaag ggcttgctcc tcgctacgaa gctgtgtcgt acgaattccc
    20221 acactgacaa ccttacccga tacagtaatc ggtccatttg tcagaacgac ctcatctccc
    20281 acatccagtt gacgttcaaa gaggatgaaa aagccattga tgacatcaga cagaaagcct
    20341 tgggctccca taccaatcgc taccccagca ataccagctc cagccagcaa actagaaact
    20401 ggcaaaccta aaatcgacaa aatgcagtag agtaaaaaga aatatagcgt ataattaaac
    20461 acattttcta gtaaacgtga gatggttttt tggcgtccga catcatgacg agacattttt
    20521 agagaaggtt tgacaattct ctgcaccatg gtatgaagca tttttttagc aatataaaat
    20581 acaatcaaaa gcagtaaaag agaaatgacc ttggttagaa tattctcgat aatggttgtc
    20641 acatctagct tttcaatata agcctgaata aatttttgca tataaaactc ctttatttca
    20701 ttataccata ttttcatcag tctcattctc cataaatatt caaaaaatag acagaaaatt
    20761 cttgattttg tctatcattt atactataat cataatcact acacaaaaag gagattatta
    20821 tgaaaagaat cattcatgct tggaataagg caagccttgt caagcgtatc ttgattggta
    20881 tgctttgtgg ggaatcctag gactgaccct tcctaatctc tcagggattg ggctactcgg
    20941 ggatttattc gttggaggtc taaaagctgt tgctcctatc ctagtctttg ctctcgttgc
    21001 caatgccctt tcccaacatc aaaagggaca agatagcaat atgaaaactg ttgttttctt
    21061 gtatatccta tgatagggac tttcgccgct gctcttgtag ctgtactagc aagtttcatc
    21121 gtccctattg aaattaccct aaatagtgcc aatactgaaa ttgcaccacc agatgggatt
    21181 gggcaggtcc tcagcaacct cttgctcaaa ctggttgaca gcccagtcaa cgccctgctt
    21241 actgctaact atattggaat cttatcttgg gcagtcattt ttggaatcgc tatgagagaa
    21301 gccagtaaaa atagtaaaga attgctaaaa actatcgctg acgtgacttc taaaattgtc
    21361 gaatggatca tcaatctgac tccatttgga atccttggtc ttgtttttaa aaccatttct
    21421 gacaagggag tcggaaggct tgccaactac ggtattttat tggttctatt agtaacgact
    21481 atgctttttg ttgcccctgt ggtcaaccct ttgattgcct tcttctttat gagacgcaat
    21541 ccttaccctc tagtttggaa ctgcctccgt gtcagcggtg tgacagcctt tttcactcgt
    21601 agttctgcgg ctaacattcc tgtcaatatg aaactctgcc atgaccttgg actcaaccca
    21661 gatacctatt ctgtttctat cccactcggt tctactatca atatggctgg agtagcgatt
    21721 accattaacc ttttgaccct tgttacagtt aacactcttg gaattcctgt tgactttgcc
    21781 acagcctttg tcctcagtgt ggtagcagct atctcagcct gtggtgcttc aggtattgcc
    21841 ggaggttccc tccttcttat cccagttgct tgtagccttt tcggtatttc taacgatatt
    21901 gccatacaaa ttgttggggt tggttttgtg attggtgtca tccaagactc atgtgaaaca
    21961 gcccttaact cttctacaga tgtcctcttt accgccgttg ccgaatacgc agcaacccgt
    22021 aaaaaataac tcatcaaggc aagcctgctc atgtcttgtc ttttacgctt ttattctaac
    22081 ttattaggaa attcttatgt ctattagcca acgtacgacc aagctcatct tagctacctg
    22141 tcttgcctgc ctgtttgctt attttctcaa tctttcgtca gcagtttcgg ctggaattat
    22201 cgctctcttg agcctatctg atacgcgtag aagtacttta aaactggctc gcaatcgtct
    22261 tttttctatg cttctagctc tggctatcgg tgttctagct tttcacttga gcggatttca
    22321 tatctggagt ctcggcctct atctggcctt ctacgttcct ttagcctaca agatgggctg
    22381 ggaaattggc atcacaccaa gcacggtttt ggttagccat ctcttggttc aagagtcaac
    22441 ctctccagac ctcctagtca acgaattcct tctctttgct atcggtacag gatttgcctt
    22501 gcttgttaat ctctatatgc cttcacgaga agaggaaatc cagcactacc acacgctggt
    22561 ggaagaaaag ttaaaagata tcctccagcg cttcaaatac tatttatcca gaggagacgg
    22621 acgcaaccga gcacagctgg tagcagaatt agacacgctt ttgaaagaag ccctcagact
    22681 ggtctatttg gatcactctg accacctctt tcaccagacc gactaccata tccactactt
    22741 tgagatgaga caacgacaaa gtcgtatcct gagaaacatg gcccaacaga ttaacacttg
    22801 tcaccttgcc gccagtgaaa gcctgatctt agcgcaactc ttttcaaaaa ttgcaggtca
    22861 actgagccag accaatcctg cttctgattt gctagatgaa attgaacgtt atctggaagt
    22921 cttccggaac cgcagtctgc ccaagacaag agaagaattt gaaacccgcg ccacccttct
    22981 tcaactccta cgtgaagcca aaaccttcat ccaagtaaaa gttgattttt accaaaaata
    23041 tagacagtaa tactcttcaa accacgtcag cgtcgccttg ctgtatatat gttactgact
    23101 tcgtcagttc tatccacaac ctcaaaacga tgttttgagc tgacttcgtc agttctatcc
    23161 acaacctcaa aacggtgttt tgagctgact tcgtcagttc tatccacaac ctcaaaacgg
    23221 tgttttgagc tgacttcgtc agttctatct acaacttcaa aacggtgttt tgagctgact
    23281 tcgtcagttc catccacaac cttaaaacag tgttttgagc agcctgcggc tagcttccta
    23341 gtttgctctt tgattttcat tgagtataaa aaagaaaact tcagaccaat ccacaaaagg
    23401 tgaatatctg aagttttctt ttatttataa gtaatcacca taaaggttaa tagtagaaca
    23461 aataaagcca aactcaccaa taaagtgagc accttgacca aggtgttgct ctgccagtag
    23521 cttggtttac caatattact agtggcatcc atggaaaata gttgattttg acggggttgt
    23581 atagttacca atacaatcaa agcaagagat aggataatag ctaaaacaat tagcatttca
    23641 atcattgatc tacctcaaaa ttcccaacaa agtaaagagc aaaccaatca gaatcattaa
    23701 gcccagtaaa agtgaaaaag ttttactaat cttctcccct cgggtttctt tttccttctt
    23761 gatgggtttt tgtttcaact cttccatgcg accttcaacg tctttgtaaa ataaatcttc
    23821 ctctgacatg ttagcctcct aaaacagttt gcattatttc ttgatatcgc accaagtcaa
    23881 cataatttgc atgttggcct tgtttgccaa gtgcctgacg catttgatca acatctgaaa
    23941 gggccaattt aatggtctca accaaggcag caacttcact actttcaaat agatgttctg
    24001 gagcgatata aagtctattg tgaaccgttt ggttaaatcc aagaatcaag agattgtgct
    24061 caaaggcctg acgcactgcc tgcaacaact cattgctgtg attgatatcc aagtaaatat
    24121 ccgacagttg atacagctcc tgaatcttct gtggactagc attctggtaa aggaccacat
    24181 taggatagcg aagcatgtct aagagcttag aagacatctc tgtcactgct gcgatacgga
    24241 aggtaacatc aggcaaggct tctacgattg cttctacttg ctcaatctga tctgaattgg
    24301 tcaagattaa ggcatctcgt cttaggaaat tatcacgttt gaactggtaa tgataaccca
    24361 agtgcacaaa ctgatcatgg tatttctcgt cagttaactc taaagcgcgc tcataagtcg
    24421 ccttatttgg aatgatgatc ttcttagtac gcacattatc actttccaaa atcaactgca
    24481 tattacctgg aatggcatca tagagaggtt cctgccatac caagacatcc gagccagatt
    24541 tatctggatg atggaaggaa accaagaaag gagtcgctag agtattaaag ataagctgac
    24601 tggtatctat ttccaaatct tgcaaaaaga aggtgataaa ttcaacttta tttgcaaagt
    24661 aacgcatgga ctgaccaggc aaagtcaata agatatcacc cgtcacatgg ttttccagta
    24721 aaacttgttg gccattgaca tcttggtaaa ctgtcataat cggctcgcta tctgcgctat
    24781 aagtggtttt agcaaagcaa gcaccaaagc gattgtagtg gtcaacctga cgtactcgac
    24841 cttctaggtc tttccagtct acctgtttaa ccaagcgagc ctgcattcca tcaacataat
    24901 gaatgacagc cctctcctgc gtcacatctt caatacaagc agactgatta tctcctaaaa
    24961 tttcccaaaa atctgaaacg ggaacttggt taaaatagag aggttttcca tcctcgtaac
    25021 ctagataata ggtaaaagga gaaagcagac catcaggcag aaaaccatct gcatcgatga
    25081 ccactccaag ttgagaaaga ccagtagcga ctagactttc atgtaaatct ctactttctt
    25141 gactgtaact atcataaagt tcaatcatgg agcacctcct ctactgtttt cttccacttt
    25201 tctaaaattt ctttggtcaa gaagccttct gcaatttgat aagaataggc acgcatagct
    25261 tccaaacgat tttcttgata caattgacaa atcttagcgg cataagcttg cttgatttgg
    25321 tcttctacat ggtcagatga acttggaatc aaataaccat tttgcccatc ctctataaag
    25381 gtctgattac cataaggcac atcaaaacca attagaggta gacctgaacc aatagcttcc
    25441 atcaaggtca gaccaaatcc ttcgctggta gaagccgtta agtagacctc atactggcta
    25501 taaatctgcg aaagttccgc atgccccttg agttggatat agtcctctgc ctgatgattt
    25561 gcaataattt ctctaagcag agaatcttct ccaccactac catagatatc aaaggttagt
    25621 tccggtaact ccttatgagc ttcaatcaca gctttcacaa gccaatcaat gtgcttttct
    25681 ttggcaagac gtgaagccgt aatcaatgaa aatggtttgc gcccttgact tgaatctgtc
    25741 aaggaatcaa tactgcctac aggaatggta acaatctttg gctgatgctg agtatatttg
    25801 gcaaattgct cttgtagaac ttcattttgt ctatcagtag acacgataaa gaagtcaacc
    25861 ttatctgcat tggtaaactg atagtcataa tagttattcc aaaggatata gtcctcattt
    25921 gtagcatttt cactataatg ctccgcatga acaactaccg ctagatgtgc tgtctgtgct
    25981 tcctcaaaca caacctgtcc aatacctgtc tccctatcca gaataaccaa atcagacttg
    26041 ttcaaattca aagatttcat aaaggcacgc acaaaagctt gctttccata gaaaatctta
    26101 tccttgaaat gataaacttc ttccttccct tgattcatca aaatatcata gactggagtc
    26161 ccgtcttcat tgtaaaaagt tcgttggtat aagactgcaa cattgtcctt gggagcaaaa
    26221 tactcgctac aataacgcgt ataagaaaag taatccttcc gaatcaggtt tcccttaaaa
    26281 acatactcgg catgttgaac caagtccttg ttctcatcaa ccaaataaca ggttacaaac
    26341 ttatcttggt caaaaaagaa tacacgtaaa accttgccat ttttttctct gtgactttct
    26401 tcaccaccaa agtaagccaa gacatcatcc actgtcacgc tagtaggtgc aattttgata
    26461 tctgtgaaat gattataaag ccagataacc tgattatcat caaaaccaat attggctgtt
    26521 aagtgctgaa tattatcggc taaaatcata tctgtaaaga taaacttaga ggacagattt
    26581 aatttccgaa aaacaccagc acgataggct tgagcgtatt caacaccgct actagcccaa
    26641 ccaattccta aatttatatt gtaaattgtc atattttctc ctcttatgga aaatgagtca
    26701 cgatttcacc ttttggagtg acctcaacca gccccatcag gagattacgc accatatccg
    26761 cacggatttg ttctttcata gcttcaaagc ccgcgtaggc ttcttgatag tactctacga
    26821 ttggattttt ctgactagca gattgaccac cgatagccat ggatagctgt tgtagatagt
    26881 ctacctgctc tacccagttg tcatcaatgg ctttaagcag tgaaagtcgt aaaaactgtt
    26941 catataagtc atgttgatta agtaattctt tcttttcaga aagttcttta tcaatcacct
    27001 gcttcataaa gctacgaact gcagttttgt cagttacatc tatataatct ggaacctctt
    27061 taacatgaaa actaatattg gtcacaataa agtgaaacaa taattcacga ctagcatagt
    27121 gatcagccgc tacctcttct gtatatctct caatgatatc cacaacaaca tcctctaagt
    27181 cacgagaacc atctattaga cgatttctct ctttatagac tatatcccgt tgtatattca
    27241 tactttcagc atactccaga gtctgacgac gtgctgaacg tccagcacta tcactggcat
    27301 gctgagcctt ttcgactagt ttccggtatt tacgaccttt caatacttcc ggttgagtca
    27361 tatcttgaac ctgatagtct ttgtactttt tatgcaccca agatggacca aatttcttga
    27421 taacatcatc ctctaaggat acaaaaaatt tactcatacc aggatctccc tgacgaccag
    27481 aacggccacg aatttgtagg tcgatccgct gactttccat ccgctcagtc ccaataacaa
    27541 tcaagccccc aagctctgcg actcctttac caagcttgat atccgtacca cgtcctgcca
    27601 tagaggtagc cactgtcaca gcccccatct gacctgactc ggagataatc tgagcctcac
    27661 gcgccgcatt attagcattt aggacattat gggcaatccc ttcacgaaac aagagagacg
    27721 aatagagttg agacatttca actgagccta caaaaacgag taaaggattt cccttagcat
    27781 ggtattgctt gatgtactcc aaggatgcat acactttttc aggtaaagtg atatatagat
    27841 tatctggata gtcaatccgt tgtctcggac gattggttgg aatgcgtact acagacatat
    27901 tgtaagtttc aataaactct ttttccgcga ccttacctgt ccctgtcata ccagatatct
    27961 tattaaacat cttaaaaaga ctctgatagg tgatcgaggc catagcccgc gtctcaggag
    28021 ataatttgac atgttccttg gcttcaatag cctgatggag acctccttga agtttagtca
    28081 tttccattag acgccctgtt cccttatcaa ccagtaccat ctcatttcca cgaatgatat
    28141 agtccttatc tttagtaaag agcttatgag ctcgaatcgc ataaaccaaa tgacgagcaa
    28201 aagacgcatg ctcttccttg tataaattat caatccctag gaaattctca gcagacttgg
    28261 cccccttagt agtgagccaa acctcctctt tctcctcttt aaagatataa tcctctcctt
    28321 cgaccaaggt tgttacaagt gtatcaatga tcgcatagta attagactga acacgaggag
    28381 aacccgcaat aatcagagga gtttgtgcac tatcaagcaa gatatcatca atttcatcaa
    28441 taataacata gttaaacggt cgtaaaaact taccttcttc attcgaggct aggttatcat
    28501 ttagataatc aaaacctaaa ctactattgg ttgtgtagat gatatccgaa gcatagataa
    28561 gcttcttttc ttcagctttc atttccttct ttggatcttc cgtaaatggt acaccaatgg
    28621 tcaatcctag aaaacgataa acttggccca tttcctcggc atcacgcttt gataaatact
    28681 cattaggagt cacaaccatc actccttctc ctgaaaaagc gttcaaatag acaggcatgg
    28741 tagctgtcaa ggtcttacct tcccccgtat tcatctcagc aacatttcca tagtgcatga
    28801 caatagctcc catgacttga acatcatagg ggaacatccc taaaatccgc ttatctgctt
    28861 cacgcaccac agcaaaagct tcaaccaaaa tatcgtctag actttctccc tcggaaagac
    28921 gctgacgaaa ctctactgtt ttagctacta attcttgatc cgaaagagag gacatcttgc
    28981 ctttcagggc attaatctgc tttaaaatct ttttcacttt cctaagctgg aaatcttgac
    29041 ctaaacgtct aaacacttct gatctccttg atagaaaaat gataaaaagt taaggactca
    29101 aatccagcac ttaaaagaga aacttgataa gtataactat cttctggata agtaaatatg
    29161 aaatctttcg ctttttctac ctttttttct aaaatatcac catagcggtc aaaaaaagtt
    29221 atcttggtat aaactccatt ttcaggctga caatcaaaaa ccagtgatag ttgatactcc
    29281 tgctttcttt ttaataaggg aagctgaggt tgggttcgtg cagcctggta attgacacta
    29341 gaaaaccaag tctttagaat ctcaccagat ggcaatagag gattatacag acgaacactt
    29401 ttgtcaaggt aataagatac agttgttcca tacatataag tcccaccaac ttctccccaa
    29461 taaatagact gtctctgtgt aataatcatc ttttctccct tccaaaacca gtctctaaga
    29521 ccattctata aaagtgcaaa aaccaagaaa tattggtatc tgtatcatca ttgtgtcgtc
    29581 cagcagttcc tttagataaa atcttcgcac ctgtattaca cagataagac actaattgtt
    29641 cataggcttg tggatccatt tcttcatctt tcatatagga taaaccaaag gttgtctttg
    29701 aaaaatttgc ttgtttaaaa attttccaaa aacgctgatc caactccgtc atatcttgag
    29761 aacttgtccc acctgtatga tgaattaaac aatcaaaagc taagttagag acacccggtg
    29821 cgtccaaacg tccacgacta gctatagttc ctaaattagc caagggctta ccaactatga
    29881 tggcatgggg ttcaaaagaa gcaccataat agagagccgg aaacgttccc atagaaagac
    29941 ctgataaaat caaatcctta tgatcaaagc ctaaataatc aagatagtga gtgatcgtat
    30001 cctttacttt tccctctagc tcatccgttc cgagataaaa agctcccccc tctaaacgtg
    30061 gatcagaaaa taaaatgaag ggacatccaa gagttttcat cataaagtaa ccctcgaatc
    30121 cttctgcagg tcgataacct gcaaaataga cagtcaaagg cggtttaaaa tcacctggat
    30181 ggaagaaata gtttatttca tcacgcttgg aatcatgtag gatatttcca ccaagtacaa
    30241 acttaccaaa ttgttttcga ctccatcgtt ggtgaagatt acctagtttg atagttccac
    30301 gacctcttgc ttcaacagat atcgagagaa agtagtctcc gtctcgacta tccataaaaa
    30361 gtgcttgctc caagtctttt tcagatacta ttacttcttc aaagaaatca tcaacagacc
    30421 cactccacat tttacggatt actaaacgaa agtcacaatt gccttccttc tcatattcaa
    30481 gccacaactc aatagggagt gttttttgca ccataatatt ataagcccaa taggcaagct
    30541 gggcaaaatc ttgcccaaac tcaccttcca aactgacata atccaatcct tgataagaaa
    30601 tagctcctgt aaaatttgga ttgacttgta tcgtcggagg aaagagttta tcaccatacc
    30661 caccgccaaa aagagattta cttaaatcat tgattagttg ttggggactt aaaaaatcaa
    30721 ttgcttgtgc acatcgtttt tttagaaaat ccacaacctc tctatcattt atttgtagat
    30781 tctggttata gaacaaagta taaggttcaa aatattttac ataggaaaat aagtctctgg
    30841 aatactgacc atcttctatt aaaactgcat gaaaacggtt aatatcctct ttttcgatta
    30901 tttcacgaag ggtttttgat gagtttgggt aaaaataata ccaactcata ttttcaggta
    30961 tgtcatagtg attttcccaa ttggcaagtc ctatctgtaa aatattaagt tcctttgaca
    31021 tttttaacct cctctatcca tttctctaat tttccaagaa attgttgtcc tgtgtgctcc
    31081 ttaatcttat caattgaata tatcaaggac tcattccact ccttcaacct atctgtgtaa
    31141 taatgtgcag ccttagaaaa ttctgtcaca tctgtcagca aataaccatt ttttaaatgt
    31201 tccacataga cggtttcaac taggttgatt tgaggaattc ctgcactaat cccagcaatc
    31261 tgtgtgtaga gatgaggatg tctatttaaa tccacaatca aacggacaaa ttctagtgtt
    31321 tttatcaaat ctaactcatc attcaagtta acaaactgta agcgtaagtc ctggtgttga
    31381 ttttcttcca ggggattttc tgcatcacca taatcaatcg cctttcccag attttcggat
    31441 tgaatgtttt cttggatgaa agactcaaca atcccttcaa cctcattcat ttgctcctga
    31501 ctagcagcaa aggctccaaa aatcacctca gtatccttat tttcagcgac aaaggacaag
    31561 acttgaagca gagcttgatt atcaatcccc tgctcaaaat ccagttgaaa ataaatgatg
    31621 gattctttct tagtttggct tcgtcccaat cgtaatcggg tgtcaaaaga tgataaatga
    31681 taacattgat gcattcgttc aggatacaac tcctgcaaca atcgtaaact atcctctcta
    31741 tccaccaaaa tcaaatccga tttttcaaaa gttacatcta aatccctaaa ggtatcttga
    31801 ggattacgtc caatgaacag actcaacagt ttaggattag tactaggtaa acgatctagt
    31861 accaactggt catgatgaga atgagaagga agcataaaaa tatcctgatc cttcacatac
    31921 gtttgcagat aattctcaaa aaattctgcc accagatctc ccatattttg ataggtaagc
    31981 attttaaagc gataacccaa aattggattg acttctacct gtcctccttc ttttaaacgc
    32041 tctctaaatt gccaaactcc cttaggattc aaatattctt gataggctgc ttgcccatct
    32101 tcaaaaaaaa taatactcga tataaaccct cgatcatcca tgatatggtg catatgtatt
    32161 tgaccatttg gttcaaaata ctgtatatca ctgatgaagc cttcaactcc atgttcaacc
    32221 ttagcaaatt tcttcccatt tttttgaacg ataatcgtaa agggactata aataaattca
    32281 cagtcatcat cccactcaat atctctaatg cttaaaactt gggtatggag attatgaaaa
    32341 tcttgcataa catcaaaaac ggaataagta tccgtttcta acacaccatg tctatataaa
    32401 aaataacgta gatgaggctg gtaagctaat actaatagac gagaatctat atcttgctct
    32461 tgaaagagcc ggatctggtg aaaggtatca tcaaactcta gacgaaaatg agaaaaatac
    32521 catggagtga tatctgcatg ccatgttctt tctgacccat accaagctgg aataaaataa
    32581 tacataaaag tctcctaaat caaaggttta taggtctcat ttagccttaa agccttgacc
    32641 tcgtctctaa tcgtaaaaat catgcctcca aacatcataa acaaacctgg aatcattgcc
    32701 aatcgtaata acttttcatc aaacaaaaca aaaagcatgg gaccacctgc cataaccaca
    32761 ttaaagagac cacctatgac tgagaaacga aggaccaatc gattaataaa tcgactagta
    32821 tccgcacctg gataaatacc ataaatgtat tctccagatt ttttcatacg gtctgcaatc
    32881 tcttctccat tcatcgtaac aaaagcaaaa atgatactaa ataaaaataa gaccgaaata
    32941 taaacataga cccacaaagg ctttccaatc ataaattcct ttgataaagc cgctaaccct
    33001 gaatgattag ggaaaataaa tcccaacaag atgaacaaat aagctggtac actaagaaaa
    33061 ctcatcacat acatataagg catcccacct gcaggattca acatgatttc gagataaaaa
    33121 tagcgtttaa atcgattgtg taagccaatt ttattaacag gaaccaaata gcgagctcga
    33181 tacataaggg caagtaaata agaaaagaca agggttaata aagcaagtaa cacaataatc
    33241 cctgttggaa tgtgtactgt ctgaaatgtt tccaaaacat cctgaggaat atttaaaacc
    33301 atactggata ggagaatgac tatagaacct ccaatcccca tactcgcatt taaatctgac
    33361 aaccaaacaa gaaaaaatgt tcctgctatc agcaatattg tattcattag aacaaccaat
    33421 attgcagaat aggaggattg tactggcagt ctcaagctaa ctgccaatga ttgaatgaca
    33481 gctatcatca aggtcaggta cattttacgg cgatcttgta tttctataga cgtagatgtt
    33541 aaacccaacc gtttagaaaa agaaaacatc tgccataaaa tcatagctga catccaaggg
    33601 gacaatccaa cagaaaaaat tgacaaactt cttagatttc cacctgttag ggcggctgag
    33661 aaggctagat aggctgttga acctcctaaa aaatctttag tatttaggtc aacaaaaggg
    33721 agagtaatac gacttcccaa tacatagata aacagtagaa ataaggtaaa tagtcctttt
    33781 tttactgcta ttgacgaata aatcttagtc ataaaacact cccctcacct tcattgtttg
    33841 tgatatggta aataacaatt cttttatttc aacttttacc atttctttgt tctgcatcaa
    33901 aaaacaactt taatctgaaa caaatatctt tatattcctc agtatctgtt aattgatggt
    33961 attctaaagt ttgcttataa tcttttaaaa gattgacaaa tcgaatacgc agaacggaga
    34021 catccaaacc agccaagaca caatccgata ttttcttaga aaacacttca acaatatctc
    34081 ttgcccagga aagatcaaat tccgttctca tgatgcttcc tgaacgtctt ctatacagat
    34141 agagattatc gtttataaag acgattttag aggctaaaag ataaaagcga tgcatagttg
    34201 cttcatcatc aaagcggcga ccatttgaaa agtgaacttc attgaataat tcttttttaa
    34261 tcaacttaaa tgtcggcaat ataaaggccg agctattgaa tttccaatct cctgcttgac
    34321 ggttcataat ttcttgtata gctaattctt cgacgcaaaa atcttgccct gttacataaa
    34381 aataaaaatt cccgtcactt tcgtcataat tatagtaatt ccctataaca acatctgcat
    34441 ccttttcttg gacttgctga taaagagttt caatcatatt ttcttttacg atatcatctg
    34501 aatcaacaat cgtgatgtac tctcccttag ctacactaat ccccatattt ttagcttgtg
    34561 ctgccccccc ttattttctt gatgcaatac tcgcacacga ttatcttgca tcataaaagc
    34621 atcacaaatt tccccagaat tatccgtaga accgtcatca actaaaataa tttctatatt
    34681 ttgataggtt tgcttcagaa tatgctcgac acactccact aaatattttc ccgtattgta
    34741 tatcggtacc acaacactaa ttaattcact cattactcta tctctatatt cttcattcta
    34801 tccactaaat catctggtct ctccacagaa aaaataccgt catagagtcc atcatccata
    34861 cttttacgtg tgatatcaaa agcgaagatt ttcttgccac tttcttgtgc ccttgtaact
    34921 acattaaaaa cctctccacc tgtattaata tctaaataaa ctatagaatc gtccaatagc
    34981 caatcaattc tactatgtaa tacattttga tatactgtta cattcgtata ctgtgataga
    35041 gaggtcagct cctcagaaca atcacacggt gcagccaaat gaaaatgcca atcaggtaac
    35101 cgttgtacta aatactctaa atgttttata tctgcactcc atgtcacaag catcacttgt
    35161 tttttagact gattgcttct ttcaaaataa tttaaatcgg aacgttgaaa agcaatctct
    35221 gaccaatcca aatctctata aacccaccat aattcacgta gtctagatat actatatgta
    35281 ttccaaggtt tatcatgact agcatagtga acaattgtag gtggattgtc atctagacgt
    35341 tcacattctt gagcaaggtg ataaatatca acacccacca tataattata tgttttatct
    35401 aaggctagcc aattatcctc aaaataaata tttaaaatac tctgatcccc aagatgaaca
    35461 acttgatttt gctcggccgc taattccaat aaactattga caatagagtg ttctttccat
    35521 tttgcaacat ccattagtaa cataccagca ttaaatccag attttcgtcc ttcataggca
    35581 tagacatcat caacagcacc aattgaatat cctttgagat ctatctcaaa caaagtagct
    35641 agttccccag ttacaatgat atcggaatcc agatacaata ccctatcaga ttcaaccact
    35701 tctgtcgcaa aaaatctaaa gtaagaagca taatttatat gaggtcctgt tttatagctt
    35761 tcaaaaagtt ctttatcaat gtgtacactg cgaattgtag aattcacaac ttccattttt
    35821 ctccccaata atttaaacca ttcaggagct atatcactgt tgagaatata aaaatcaaca
    35881 tctctattgt gatacaatac agactttata gtcgtctcta aaggaataag ataggcatta
    35941 tctgccgcta atactattga ttttctcata ctgttctcta cctcatgtaa gatctgattg
    36001 ctgcaaccat ttttttcgga atggagcttg gatagatacc ttcatatgaa atctcagaaa
    36061 gattttcaga gcaagtattg tcgaaagcta tcattggttt tttgtactta agcacaaact
    36121 catatgcatc ttctaatttt cgatcatgat tcaaatccaa atacaaatct gaagctatta
    36181 ctatttgttc caataacatt ggtaaggaat ttggatatac ggtaacatta ggaaaacgcg
    36241 ttaaagctag tagttcattt gccatatttg tataagcaac aatatgaaaa tgaacttctg
    36301 gcaattgctc cgccaaataa tcgattttct cgacacacca agaattcgtt aaattaacac
    36361 attgtaactt aaatatttgt gatttactag gatacttcac actctttgaa aaccattcat
    36421 ttaaaataac agaccaatcc atcaaagagt attcccacca aacttctctt agacgtccaa
    36481 cagaaaattg attccaaggc ttatcctgag aaatatagtg taaaattagt ggcagtggtt
    36541 cgagcggaat atcaaaaatg aattgatgtt taaaggctgc cgccccataa tcatatccta
    36601 tttgaaaatt atattgatct tcaagggaac tatattgatc tttaaacaac atattcaaaa
    36661 ttgactggtc tccttcttcc acattctcat gttctttttc tgttaagtca atcaattttt
    36721 gtcgaatagt ttcagatccc cattttttgt tgttaatcaa gagaacacca gcattgaagc
    36781 cgactcctgc tccaaagcaa gaacgagctg ctgccaaata attttcacct aagtctaatt
    36841 caaacaaatc ggtcaaatca ccagtcacaa tcaaatcact atctagatag agaactttat
    36901 cttctgttac aaaatctgga ataaaatagc gtgcaaatgt catatgattg atatgaggta
    36961 atttattaga ccaattcatt tgaaactgtg agccaattaa cttgcagtca atcaagtcgc
    37021 cccccatctc ttgtaaatat attcttattt gactaaacca ttcctgagga atgtcctgat
    37081 ttagcagata aattttcaaa tgactattgt gtctacagag tgacttcatc gccgtttcga
    37141 tttgtcgaat ataagcgtaa tcacctgcaa atgctacagc gcgtttggta tttctcattt
    37201 taaatcctta tcatttattt taaatagtct agtttaatat tcgtgcaaca atctgactgt
    37261 tataggtttc atcatcaata aattcaatat cttgatcaaa attatactct gcagtatgtt
    37321 tatgagaaaa tttaacctta gttttagctc ccattttcat ccattcatac tctgagtcaa
    37381 tatggcctac atccaaaact tgatagccca tctggcatag attataactc agaacttttg
    37441 ctgtaggacc cagcatacat aaaatcaagc gaccaccagc atacttttca atttcttgtt
    37501 caatttcatg aactctagaa aaggcactat gagaaggaca gataattcgc ttaatagaat
    37561 ttgcctcatc gaataaatca tttccgacac ctgaacgaga agtcgcacct tcgactatca
    37621 gtaagtcacg gttttcccaa atgcttttca atttttcaaa ttgagcttta gcttgactct
    37681 tgtcttcaaa atcgatataa gggcgagata caaaggttga gccataccat gaatcactgc
    37741 ataactctct gtaaaaatcc atataatgat ccatgtgatc tttccaaaat ggaatcgccc
    37801 acgatgtaaa cctaaaacga tctgtaaaag catcaggaag gcacactact aaatcttctc
    37861 gactttcttg gccgataatg tccctcatga ttgaaaccaa ctcttcatca taatcctggt
    37921 agggaattga atgccctgca agcatattga tttccccatc tccaaaacga actaaagaag
    37981 agttgtgttc aataatataa tccaaggttt catctatccc tttcacctgg attatatcaa
    38041 gcggtttttc tagcatatcc ttagttatca atttttgcaa atcagccaac attcgttcag
    38101 gatgttcact tgaatacaac ctttggccat tattcccatt ttgagattta taaaaggcta
    38161 gtataggttt agatagatga gccatttctg caacgatatc ggatgttgaa gtcagtaggt
    38221 tgatatctaa ataagcatcc atcttctcct tcaactcgtc tagcttatct ctagaaattg
    38281 ccggatagag ctgaatatta ggataacgat tagacaaatc atataatttt ggccccatag
    38341 ctgtccaagc agcaacttga aaaacaacat ttggcaactg tccagccaag taatccaatt
    38401 gttcgatatc ctgagaagcc gtaaacgtta aacaagttaa acttggaagt tgtcgaaaac
    38461 aggtaagatg tccgtttttc ttaaaatctt taatcgtatc aatcataaag gaaactttcc
    38521 cattttcgaa aacgatttgt cctaactctc cgtgctgagt cgattgaaaa gctagtagcg
    38581 ttttttcttg ttcttgcaaa gattttaaaa agttctcatc tgcactacca tgattgatat
    38641 ccaaatatag atttgttgac tttttcagct tatctaatac aggaggaaca atttgtggat
    38701 gcaatctcac attatcatac acagctaatt ttatcagctt atcacccata tccgtccaag
    38761 cagcaatatg aaataccaca tctggtaaag ctgtgactaa ctcttctatt ccttctaaat
    38821 cttgggaatt tgtcaaagtt aaacaagaaa attccttatc taaagacgat gtcagttcaa
    38881 actcccctat atgatgttgt aaaattttag tccattccaa atcatgaaat tcccaccata
    38941 aatcacgata acgattggct atcaaggtgg tccagggttt tctgtaagac acaaaatgaa
    39001 taatactagg aggtactaac tcattaaaat aattttccca tttattataa aaagcagtta
    39061 catcatgacc cacttgaagg ttaaattctt tatccagctc taaccaatca tcttgtaaga
    39121 cctgattaaa aatcgtttga tcaccattaa aatgctcgaa acggccttct tcaacttcct
    39181 tcattgtaac aatgctctgt tcaattagtc gttcttttaa tttctcttga cgccattttt
    39241 tattgttgat taataaaaca cctgcattaa atgtaattcc atctgtatct ttaactgctg
    39301 cgagtgattt ttcttctaaa caaatactaa ataatttctc taaagaagta tttacaatca
    39361 aatcactgtc taaatataaa accttatctt cttggatata atctgcaata aaatatctag
    39421 tataggtaat gctactaatg tgatcttgct tttcccaatc ttgaaacaca gtttgttcag
    39481 gtagcttcac atcgataatc tcactaccta acatgcgagc tatttttcgt ggtttgcgaa
    39541 accaatctgg cataatatct tgatttaaaa tataaatctt aacatctcga ttgtggtata
    39601 aaatagattt tatggttgtt tctaactgcc tgatgtaatt acgatcacca gctaatacaa
    39661 ttgttttaat catcttgttc tcttattcaa ctcccaaatg gtaaattgca tctaccaata
    39721 attttttagt aaaataacct tcttttagca aataactaaa ggtttttatc cgattcgtca
    39781 tttcttgata ttcttgtaga ttcattttat caactatcgc atgaacttct tctagactat
    39841 tcgccacaaa gcctaagcct tgatctacta taaatttagc agttgacaag ctacttggta
    39901 caatgactgg gatgcccgct gtcagatagg tactcacctt atgagatata tttaaggtat
    39961 aatattggtt gctttctcca tcgttttgat aagttcccca gacaaggcca aatccaccct
    40021 ttgataattc tagcaacaat tcctcatctt ttttccatcc ttcgatgctg agatttctag
    40081 cactagaact agcttcccct ttatttgaaa atactctcaa aggcgtatct tgagaccaat
    40141 tttgtaagtc tggaaaacgc tctaaacttc cagcaaaaaa aagttctttt ttaaaagcag
    40201 gggtgtataa ggataaatca tgaggatgat cccacatccc ttgaacaaga atcttcttag
    40261 tcgtcaatcc ttcttccatc aggcgtgttt tcattctctc tgacggcact atcaaaacat
    40321 ctgatagatt atacatgtac atatagtctt tcatgagata atagttacta tcaaacatga
    40381 ggggaacaac atcatggata aagcaaataa ttttcacctg catatccttc aacttatcaa
    40441 acaagagacg atcaaattca aagccattcc aggttggaga ctgaaagact aaaatatccc
    40501 caatagaaat actggccata ataccatcca gacgcttatt catttcagaa ggactatctg
    40561 aagcaatgtt gtaaaaataa ataccaacct ctctaaatcc cagttgacta gctatctttt
    40621 gaacagcatt ttgagctaag ataaccgtac tatcaccagc catgccgtat aaatttgtta
    40681 aatgtagttt catattacgc tatctcattt tttattacta tctacggaag taaagacaat
    40741 ttttccatca ttcttctata aatctctgtg aactgcatat tttgttcttc taattttgct
    40801 atcactcttt gtaatctatt tttataaatc aaaatatgat tggtcaagtc atagtctgaa
    40861 cttgctaaaa tagctatctt ttcttcccta gccccgattt catcatacat acgcttttca
    40921 ctccatgtat tcgataaagt atcagataaa ccaacacggt accagtaaac acaacgattc
    40981 aaatagacta tcctcgaagc tcttagaagt accttccatg tccagtaagt atcctctgca
    41041 atttttccta taggaaatgg taaatcttgt agtaactctc tcttgaataa cttcaagaca
    41101 gctacagtcc agttcccatt tctgacttct tcgacacctt ccctatccat gattgcttta
    41161 ccttctatca cttccagaga atcatctgga tccgtaacat aagtcatata cacatagcgt
    41221 gtttcatcat aagaattata acgcccgata ctaatatctg cgttttcctt tttcaaagca
    41281 ccatataatc ggtctaaagc atcatgttcc aaccaatcat cagagtctac aaaagtaatg
    41341 tacgcccccc ccgaacattc aatacctagg ttacgagctg atgaaagacc gccgtttgct
    41401 ttctcaaaat atttgaaacg agaatctttc tctacaaatt cttcacatat tttggatgaa
    41461 tgatctggag agccatcatt aaccatgata cattcaaaat tcggataagt ttgtttttga
    41521 atactatcca aacactgtcg caaataattc tcaacgttgt agattgggac tacaatacta
    41581 attagttcat tttccatata ctaactttcc tagacttgat ttattctatt tccctcttaa
    41641 tctcttctct ttacaacaag atttccatta ttataaacta cactgtttga tggaatatca
    41701 ttgcgtatga gacaacctgc tccaataatg gtattatccc caatcgtcac tccttttaaa
    41761 atcgtgacat tacttcctat ccagcagtct ctgccaactc taatcggcgc tgtagtccac
    41821 tgccactttt caatcttttc agcagtataa atatggtcgt gatcataaaa acgaacaccc
    41881 tctcccatca tggtaccagc tccgatttca attctttcca tacagttaaa actacaagag
    41941 ttgttgataa aaacaccatc atgcagtatt aacttaccag aagagacatg aaaattttca
    42001 aaatttctgc agatgacatt tgctcctaca atgaagtgag ccttatcatc gattttaaag
    42061 acattccaag tcccatcttg gatgattttt tcttgatgat tggtgcctac tctgacttca
    42121 ttcagatagt ctctcactct agaaaccaat ttgtctggtg tacttgatag aaaaacttcc
    42181 tgcccctgat ttccatggac tgtattgtca aaagcaaaga cagattttcc agcctgtaca
    42241 aacttggaga caatagcatc tacttcttga aagtgattga tatctagtaa aaagtcacag
    42301 gtatcgacta gaaagtttag ctgttcttca tttgtaatcg ttcggagacg gacattatag
    42361 ttcgtttcta agctacggat tttctcggaa aattgaacag gtgctgcaat ataaaaacag
    42421 atatttggca aggattcaag gagataatcc aactcttcaa tctgatcact aacagtcaaa
    42481 atcagagcat ctcctactaa atgatttttc ttcatttgct tatttctctc aatttctcaa
    42541 tcattgcttg aacttggtca acagcatata cctcctgacc tgcttcatag gttttggtat
    42601 tttcaaagga caaaatagtt tttccaagtc ttgcaaattg attgataatt tcctctgttt
    42661 tttcaccatg attaatatct aaaagtactt gactggtttc taccaattca ttatcgacat
    42721 ctaccaaata gtgaattccg ttaaatatag tcacgtttgg ataaattgtc atctgagcca
    42781 atcgatcact aactattact ctagctgcta tcttaaactg aatatcaggc aaggattgaa
    42841 ccaatgtctc aatttgttca atatggtctg aggcagtata gattagacaa gtgaaaggtt
    42901 cctttattgg atagatgtga gatctttgta atggatgtaa atgatggttt tgtcccaatt
    42961 ctgtccattc aagcccatga tagtaccacc aaacttcacg ataggtttgg gccgccaaat
    43021 ctttccacgg tttccgatga gaaagatagt gaataatagc aggataatcc tgaccctcag
    43081 gcaattgata atcagcaaac tgtttatgaa tgacaatatg attataatca aagtccaatt
    43141 ccaaccattt atgttcaaaa agcatattca agatgctctg atctgcctga tccaccttat
    43201 catgccattc attggttaca tcaattaatt tttgggtcat attctctttt ttccaaaaag
    43261 cattgtttac caagagaaca ccggcattaa agatttcttg accaaaataa gctctgcccc
    43321 caaaatctct aacagcagcc aaaggataat cttgtaagtc tgtagcaaac aaatcatcaa
    43381 gatttttcgt tacaagtaaa tcacagtcca agtagagggc cttatcttct tgcacgaaat
    43441 cagctatgaa atagcgtaaa aaaactgtgt aactaatatc cgttttataa catgaaattt
    43501 gctcagaagt tacccgacaa ttaataattt ctgagtcaaa cttctctaag cgcttattta
    43561 attgcttaat ccattcattt ggaaaatcgc tatgaatcag ataaaaacga atcgaacgat
    43621 tatgataaca aatagacttg attgtcgtta aaacttggtc tacatagcca tagtttgctg
    43681 ctaggacaat ggctttcttt tcacttgatt cttgtaccgt taactgattt aaaagtcttt
    43741 ttttcatttc aaactcttta tatattgctg tgtcagataa accactagct tgaccgttgg
    43801 cgagactgac ttccaacatc tgacgataaa ctgccaagtg tttctctaga ggatatccca
    43861 tattagctag tagcgtaata cgttcagaca tagcatcaac taaggcgtgc atccactttt
    43921 ctgtccaaac tcttgataga ctaccttttc taatccgata agcataaaga cctttattta
    43981 aataaattac cttttccgat aataaatata ccttttgatt gaggtaacca tcttctccta
    44041 atttacccat gtcaaagcgc aactgctcaa acaatcttgc cttatagagt ttaccacaag
    44101 cagatatcaa agcaaaactc ttcatttctt gagtttcata acaagttctc aaagatggaa
    44161 acattgtcat ataccttatc ataataggag tctcctgata tatgaaagta gaacattcct
    44221 tcactttcgt tgaaagaata gtaattccca actgcaatat cagcttgata ttctgttatt
    44281 tttttatata gggtttctac ataatctaac tcaatccaat catctgaatc cacaaaggtc
    44341 acataatttc cggacatatt attcagaccg gtgtttcgtg cggcagaaat accagcattt
    44401 tcttgttcta tatagagaat tcggtgatcc atttctgaaa attctttaca aatttcacct
    44461 gaagcatccg tagaaccatc attaacgaca acaatctcaa tatttttata tgtttgagaa
    44521 ataatactat ctagacattt cctcagatag ttttctacat tgtatactgg tacaatgacc
    44581 gtaattttat catccactag caattttctc cttgatttat gtgcgcgagt tagtttagcc
    44641 taactttaca ggttgtctta ctcttcttca tcacgtttac ggcgtttcgc aaccaatcca
    44701 atacctgtaa cagctgctag aactccaagt aacacagatc caattgacga ctcagtacct
    44761 gtattaggca attctttttg ggatttacct gtcgatccag aagcatttcc aacttgtgag
    44821 ttcgaatggt ttgctgaatt tgaaactgat gtacttgctg aggctgacgc actcgttgat
    44881 gctgactcag acgcactggt tgatgccgat tcagacgctg aggtgcttgc tgatgctgag
    44941 gcactggttg acgctgaagc tgaggcgcta gtacttgctg aagccgaggc actggttgat
    45001 gctgaggctg aggcgctagt acttgctgaa gctgaggcac ttgtcgatgc tgaggccgaa
    45061 gcactggtac ttgctgaagc cgaagcactc gttgatgctg aggctgaagc actggttgac
    45121 gctgaagctg aggcactcgt tgaggctgaa gccgaagcac tcgttgatgc ggaagctgac
    45181 gcactggtac ttgctgaagc tgaggcgctt gtgcttgctg aggccgaggc acttgttgag
    45241 gccgattcag aagctgaggt actcgttgat gcggattcag atgctgaggt gcttgctgag
    45301 gccgaggcgc tggttgatgc agaagctgag gcactggttg acgctgaagc tgaggcactg
    45361 gttgaggccg attcagaagc tgaggtactg gtgcttgctg aagctgaggc actcgttgat
    45421 gccgattcag acgctgaggt gcttgctgaa gctgatgcac ttgttgatgc tgaggctgag
    45481 gcgctggttg atgccgattc agacgctgag atacttgctg aggctgaggc gcttgtactt
    45541 gctgaagtcg acgcactggt tgaggccgat tcagatgctg acgtacttgc acttgttgac
    45601 gccgatgtgc ttgcacttgt cgatgctgac gtgcttgccg atgtacttgt gcttgttgat
    45661 gctgacgtgc ttgctgaagc cgaagcactg gtgcttgctg aagccgatgc acttgtactt
    45721 gctgaggttg atgccgattc agacgcactc gttgatgcgg aagctgacgc actggttga
//
LOCUS       DAVBBO010000009        45159 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ST1
            SAMEA2066453-rid20184263.denovo.009, whole genome shotgun sequence.
ACCESSION   DAVBBO010000009 DAVBBO010000000
VERSION     DAVBBO010000009.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2066453
            Sequence Read Archive: ERR351777
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 45159)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 45159)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980402.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980402.1
            Genome Coverage       :: 176x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:17:33
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,141
            CDSs (total)                      :: 2,104
            Genes (coding)                    :: 1,953
            CDSs (with protein)               :: 1,953
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 16S)
            partial rRNAs                     :: 1 (23S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 151
            CDSs (without protein)            :: 151
            Pseudo Genes (ambiguous residues) :: 0 of 151
            Pseudo Genes (frameshifted)       :: 73 of 151
            Pseudo Genes (incomplete)         :: 76 of 151
            Pseudo Genes (internal stop)      :: 40 of 151
            Pseudo Genes (multiple problems)  :: 32 of 151
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..45159
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2066453-rid20184263.denovo.009"
                     /strain="ST1"
                     /db_xref="taxon:1313"
     gene            complement(56..1066)
                     /locus_tag="VQU30_000501"
     CDS             complement(56..1066)
                     /locus_tag="VQU30_000501"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YeiH family putative sulfate export transporter"
                     /protein_id="HET2446671.1"
                     /translation="MSFLSKNGAGILACLLISIVSWYLGGFFPVIGAPVFAIFIGMLL
                     HPFLSSYKQLDAGLTFSSKKLLQYAVVLLGFGLNISQVFAVGQSSLPVILSTISIALI
                     IAYLFQRFFALDTKLATLVGVGSSICGGSAIAATAPVIDAKEKEVAQAISVIFFFNVL
                     AALIFPTLGTWLHLSNEGFALFAGTAVNDTSSVTAAASAWDSLYQSNTLESATIVKLT
                     RTLAIIPITLFLSYWQSRQQENKQSLQLKKVFPLFILYFILASLLTTLLTSLGVSSSF
                     FTPLKELSKFLIVMAMSAIGLKTNLVAMVKSSGKSILLGAICWIAIILTTLGMQTLIG
                     IF"
     gene            1215..2384
                     /locus_tag="VQU30_000502"
     CDS             1215..2384
                     /locus_tag="VQU30_000502"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HET2446672.1"
                     /translation="MDLTKRFNKQLDKIQVSLIRQFDQVISEIPGVLRLTLGEPDFTT
                     PDHVKEAAKRAIDQNQSYYTGMSGLLTLRQAASDFVKEKYQLDYAPENEILVTIGATE
                     ALSATLTAILEEGDKVLLPAPAYPGYEPIVNLVGAEIVEIDTTENGFVLTPEMLEKAI
                     LEQGDKLKAVILNYPANPTGITYSREQLEALAAVLRKYEIFVVCDEVYSELTYTGEAH
                     VSLGTMLRDQAIIINGLSKSHAMTGWRLGLIFAPAAFTAQLIKSHQYLVTAANTMAQH
                     AAVEALTAGKNDAEPMKKEYIQRRDYIIEKMTALGFEIIKPDGAFYIFAKIPAGYNQD
                     SFAFLKDFAQKKAVAFIPGAAFGRYGEGYVRLSYAASMETIKEAMKRLEEYMREA"
     gene            2381..3151
                     /gene="recO"
                     /locus_tag="VQU30_000503"
     CDS             2381..3151
                     /gene="recO"
                     /locus_tag="VQU30_000503"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000616164.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RecO"
                     /protein_id="HET2446673.1"
                     /translation="MIQSITSQGLVLYNRNFREDDKLVKIFTEQVGKRMFFVKHAGQS
                     KLAPVIQPLVLARFLLRINDDGLSYIEDYHEVMTFPKINSDLFVMAYATYVAALADAS
                     LQDNQQDAPLFAFLQKTLELMEAGLDYQVLTNIFEIQILTRFGISLNFNECVFCHRVG
                     QAFDFSFKYGACLCPEHYHEDKRRCHLNPNIPYLLNQFQAIDFETLETISLKPGIKQE
                     LRQFMDQLYEEYVGIHLKSKKFIDSLADWGQLLKEEKK"
     gene            3148..4140
                     /gene="plsX"
                     /locus_tag="VQU30_000504"
     CDS             3148..4140
                     /gene="plsX"
                     /locus_tag="VQU30_000504"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000717456.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate acyltransferase PlsX"
                     /protein_id="HET2446674.1"
                     /translation="MKKIAVDAMGGDYAPQAIVEGVNQALSDFSDIEVQLYGDEAKIK
                     QYLTATERVSIIHTDEKIDSDDEPTRAIRNKKNASMVLAAKAVKDGEADAVLSAGNTG
                     ALLAAGFFIVGRIKNIDRPGLMSTLPTVDGKGFDMLDLGANAENTAQHLHQYAVLGSF
                     YAKNVRGIAQPRVGLLNNGTESSKGDPLRKETYELLAADESLNFIGNVEARDLMNGVA
                     DVVVADGFTGNAVLKSIEGTAMGIMGLLKTAITGGGLRAKLGALLLKDSLRGLKKQLN
                     YSDVGGAVLFGVKAPVVKTHGSSDAKAVYSTIRQIRTMLETDVVAQTAREFSGE"
     gene            4146..4379
                     /locus_tag="VQU30_000505"
     CDS             4146..4379
                     /locus_tag="VQU30_000505"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000136447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl carrier protein"
                     /protein_id="HET2446675.1"
                     /translation="MTEKEIFDRIVTIIQERQGEDFVVTESLSLKDDLDADSVDLMEF
                     ILTLEDEFSIEISDEEIDQLQSVGDVVKIIQGK"
     gene            4425..4716
                     /locus_tag="VQU30_000506"
                     /pseudo
     CDS             4425..4716
                     /locus_tag="VQU30_000506"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS5/IS1182 family transposase"
     gene            4919..5149
                     /gene="blpU"
                     /locus_tag="VQU30_000507"
     CDS             4919..5149
                     /gene="blpU"
                     /locus_tag="VQU30_000507"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001093487.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin-like peptide BlpU"
                     /protein_id="HET2446676.1"
                     /translation="MNTKKMSQFEIMDTEMLACVEGGGCNWGDFAKAGVGGGAVRGLQ
                     LGIKTRTWQGAATGAAGGAILGGVAYAATCWW"
     gene            5864..8017
                     /locus_tag="VQU30_000508"
     CDS             5864..8017
                     /locus_tag="VQU30_000508"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000668284.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide cleavage/export ABC transporter"
                     /protein_id="HET2446677.1"
                     /translation="MKFGKRHYRPQVDQMDCGVASLAMVFGYYGSYYFLAHLRELAKT
                     TMDGTTALGLVKVAEEIGFETRAIKADMTLFDLPDLTFPFVAHVLKEGKLLHYYVVTG
                     QDKDSIHIADPDPGVKLTKLPRERFEEEWTGVTLFMAPSPDYKPYKEQKNGLLSFIPI
                     LVKQRGLIANIVLATLLVTGINIVGSYYLQSIIDTYVPDQMRSTLGIISIGLVIVYIL
                     QQILSYAQEYLLLVLGQRLSIDVILSYIKHVFHLPMSFFATRRTGEIVSRFTDANSII
                     DALASTILSIFLDVSTVVIISLVLFSQNTNLFFMTLLALPIYTVIIFAFMKPFEKMNR
                     DTMEANAVLSSSIIEDINGIETIKSLTSESQRYQKIDKEFVDYLKKSFTYSRAESQQK
                     ALKKVAHLLLNVGILWMGAVLVMDGKMSLGQLITYNTLLVYFTNPLENIINLQTKLQT
                     AQVANNRLNEVYLVASEFEEKKTVEDLSLMKGDMTFKQVHYKYGYGRDVLSDINLTVP
                     QGSKVAFVGISGSGKTTLAKMMVNFYDPSQGEISLGGVNLNQIDKKALRQYINYLPQQ
                     PYVFNGTILENLLLGAKEGTTQEDILRAVELAEIREDIERMPLNYQTELTSDGAGISG
                     GQRQRIALARALLTDAPVLILDEATSSLDILTEKRIVDNLMALDKTLIFIAHRLTIAE
                     RTEKVVVLDQGKIVEEGKHADLLAQGGFYAHLVNS"
     gene            8030..9379
                     /locus_tag="VQU30_000509"
     CDS             8030..9379
                     /locus_tag="VQU30_000509"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000801614.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HlyD family secretion protein"
                     /protein_id="HET2446678.1"
                     /translation="MKPEFLESAEFYNRRYHNFSSSVIVPMALLLVFLLGFATVAEKE
                     MSLSTRATVEPSRILANIQSTSNNRILVNHLEENKLVKKGDLLVQYQEGAEGVQAESY
                     ASQLDMLKDQKKQLEYLQKSLQEGENHFPEEDKFGYQATFRDYISQAGSLRASTSQQN
                     ETIASQNAAASQTQAEIGNLISQTEAKIRDYQTAKSAMETGASLASQNLAYSLYQSYK
                     SQGEENPQTKVQAVAQVEAQISQLESSLATYRVQYAGSGTQQAYASGLSSQLESLKSQ
                     HLAKVGQELTLLAQKILEAESGKKVQGNLLDKGKITASEDGVLHLNPETSDSSMVAEG
                     ALLAQLYPSLEREGKAKLTAYLSSKDVARIKVGDSVRYTTTHDAGNQLFLDSTITSID
                     ATATKTEKGNFFKIEAETNLTSEQAEKLRYGVEGRLQMITGKKSYLRYYLDQFLNKE"
     gene            9550..10257
                     /locus_tag="VQU30_000510"
     CDS             9550..10257
                     /locus_tag="VQU30_000510"
                     /EC_number="6.3.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000043309.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylaminoimidazolesuccinocarboxamide
                     synthase"
                     /protein_id="HET2446679.1"
                     /translation="MSKQLIYSGKAKDIYTTEDENLIISTYKDQATAFNGVKKEQIAG
                     KGVLNNQISSFIFEKLNAAGVATHFVEKLSDTEQLNKKVKIIPLEVVLRNYTAGSFSK
                     RFGVDEGIALETPIVEFYYKNDDLDDPFINDEHVKFLQIAGDQQIAYLKEETRRINEL
                     LKVWFAEIGLKLIDFKLEFGFDKDGKIILADEFSPDNCRLWDADGNHMDKDVFRRGLG
                     ELTDVYEIVWEKLQELK"
     gene            10459..14184
                     /locus_tag="VQU30_000511"
     CDS             10459..14184
                     /locus_tag="VQU30_000511"
                     /EC_number="6.3.5.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000361233.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylformylglycinamidine synthase"
                     /protein_id="HET2446680.1"
                     /translation="MDKRIFVEKKADFQVKSESLVRELQHNLGLSSLKSIRIVQVYDV
                     FDLAEDLFAPAEKHIFSEQGTDHVLDEVSVQADLANYAFFAIESLPGQFDQRAASSQE
                     ALLLLGSSSDVTVNTAQLYLVNKDIDATELEAVKNYLLNPVDSRFKDITTGIAKQEFS
                     ESDKTIPKLTFFESYTAEDFARYKAEQGMAMEVDDLLFIQDYFKSIGRVPTETELKVL
                     DTYWSDHCRHTTFETELKHIDFSASKFQKQLQSTYDKYIAMREELGRSEKPQTLMDMA
                     TIFGRYERANGRLDDMEVSDEINACSVEIEVDVDGVKEPWLLMFKNETHNHPTEIEPF
                     GGAATCIGGAIRDPLSGRSYVYQAMRISGAGDITAPISETRAGKLPQQVISKTAAHGY
                     SSYGNQIGLATTYVREYFHPGFVAKRMELGAVVGAAPKGNVVREKPEAGDVIILLGGK
                     TGRDGVGGATGSSKVQTVESVETAGAEVQKGNAIEERKIQRLFRNGNVTRLIKKSNDF
                     GAGGVCVAIGELADGLEIDLNKVPLKYQGLNGTEIAISESQERMAVVVRPEDVDTFVA
                     ECNKENIDAVVVATVTEKPNLVMHWNGETIVDLERRFLDTNGVRVVVDAKVVDKDVKL
                     PEERQTSAETLESDTLTVLSDLNHASQKGLQTIFDCSVGRSTVNHPLGGRYQLTPTEA
                     SVQKLPVQHGVTHTASVIAQGFNPYVAEWSPYHGAAYAVIEATARLVAAGANWSKARF
                     SYQEYFERMDKQAERFGQPVAALLGSIEAQIQLGLPSIGGKDSMSGTFEELTVPPTLV
                     AFGVTTADSRKVLSPEFKAVGENIYYIPGQALSAEIDFDLIKKNFAQFEASQADHKVT
                     SASAVKYGGVVESLALATFGNYIGAEVTLPELKTALTAQLGGFVFTSPEEIAGVEKIG
                     QTKADFTLTVNGVKLDGHKLDSAFQGTLEEVYPTEFTQAKELEEVPAVASDVVIKAKE
                     KVEKPVVYIPVFPGTNSEYDSAKAFEKEGAEVNLVPFVTLNEEAIVKSVETMVDNIDK
                     TNILFFAGGFSAADEPDGSAKFIVNILLNEKVRVAIDSFIARGGLIIGICNGFQALVK
                     SGLLPYGNFEDANSTSPTLFYNDANQHVTKMVETRIANTNSPWLAGVQVGDIHAIPVS
                     HGEGKFVVTAEEFAELRDNGQIFSQYVDFNGKPSMDSKYNPNGSVHAIEGITSKNGQI
                     IGKMGHSERYEDGLFQNIPGNKDQHLFASAVKHFTGK"
     gene            14277..15719
                     /locus_tag="VQU30_000512"
     CDS             14277..15719
                     /locus_tag="VQU30_000512"
                     /EC_number="2.4.2.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000220605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidophosphoribosyltransferase"
                     /protein_id="HET2446681.1"
                     /translation="MTYEVKSLNEECGVFGIWGHPDAAKLTYFGLHSLQHRGQEGAGI
                     LSNDQGQLKRHRDMGLLSEVFRNPANLDKLTGAGAIGHVRYATAGEASVDNIQPFLFR
                     FHDMQFGLAHNGNLTNAASLKKELEQRGAIFSATSDSEILAHLIRRSHNPSLMGKIKE
                     ALSLVKGGFAYILLFEDKLIAALDPNGFRPLSIGKMANGAVVVSSETCAFEVIGAEWI
                     RDLKPGEIVIIDDEGIQYDSYTDDTQLAICSMEYIYFARPDSNIHGVNVHTARKRMGA
                     QLAREFKHEADIVVGVPNSSLSAAMGFAEESGLPNEMGLIKNQYTQRTFIQPTQELRE
                     QGVRMKLSAVSGVVKGKRVVMVDDSIVRGTTSRRIVQLLKEAGATEVHVAIGSPALAY
                     PCFYGIDIQTRQELIAANHTVEETRQIIGADSLTYLSIDGLIESIGIETDAPNGGLCV
                     AYFDGDYPTPLYDYEEDYRRSLEEKTSFYK"
     gene            15756..16778
                     /locus_tag="VQU30_000513"
     CDS             15756..16778
                     /locus_tag="VQU30_000513"
                     /EC_number="6.3.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009729529.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylformylglycinamidine cyclo-ligase"
                     /protein_id="HET2446682.1"
                     /translation="MTNKNAYAQSGVDVEAGYEVVERIKKHVARTERAGVMGALGGFG
                     GMFDLSKTGVKEPVLISGTDGVGTKLMLAIKYDKHDTIGQDCVAMCVNDIIAAGAEPL
                     YFLDYVATGKNEPAKLEQVVAGVAEGCVQAGAALIGGETAEMPGMYGEDDYDLAGFAV
                     GVAEKSQIIDGSKVVEGDVLLGLASSGIHSNGYSLVRRVFADYTGEEVLPELEGKKLK
                     EVLLEPTRIYVKAVLPLIKEELVNGIAHITGGGFIENVPRMFADDLAAEIDESKVPVL
                     PIFKALEKYGQIKHEEMFEIFNMGVGLMLAVSPENVERVKELLDEAVYEIGRIVKKEN
                     ESVIIK"
     gene            16775..17320
                     /gene="purN"
                     /locus_tag="VQU30_000514"
     CDS             16775..17320
                     /gene="purN"
                     /locus_tag="VQU30_000514"
                     /EC_number="2.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844573.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylglycinamide formyltransferase"
                     /protein_id="HET2446683.1"
                     /translation="MKKIAVFASGNGSNFQVIAEEFPVEFVFSDHRDAYVLERAKQLG
                     VLSYAFELKEFESKADYEAALVELLEEHQIALVCLAGYMKIVGPTLLSAYEGRIVNIH
                     PAYLPEFPGAHGIEDAWNAGVGQSGVTIHWVDSGVDTGQVIKQVRVPRLADDTIDRFE
                     ARIHEAEYRLYPEVVKALFTD"
     gene            17404..17913
                     /locus_tag="VQU30_000515"
     CDS             17404..17913
                     /locus_tag="VQU30_000515"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000894002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanZ family protein"
                     /protein_id="HET2446684.1"
                     /translation="MLESKKTTRYVFYVYLMLLTWGILFKFETNPEFIAFFLAPRYIN
                     WIPFSEPLIVDGKIVFAEMLFNLIFFIPLGVCFPLIKTNLSSLRIVGTGFLISLLFEC
                     LQYILAIGITDITDLTLNTLGVCVGLLIYQIFIRVFKSQTRKWINILGMLSLGFAYLV
                     LLLLHLIGV"
     gene            17938..19485
                     /gene="purH"
                     /locus_tag="VQU30_000516"
     CDS             17938..19485
                     /gene="purH"
                     /locus_tag="VQU30_000516"
                     /EC_number="2.1.2.3"
                     /EC_number="3.5.4.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006146083.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional
                     phosphoribosylaminoimidazolecarboxamide
                     formyltransferase/IMP cyclohydrolase"
                     /protein_id="HET2446685.1"
                     /translation="MTKRVLISVSDKADIVEFAQELKKLGWEIISTGGTKVALDNAGV
                     DTIAIDGVTGFPEMMDGRVKTLHPNIHGGLLARRDLDSHLEAAKDNKIELIDLVVVNL
                     YPFKETILKPDVTYDDAVENIDIGGPSMLRSAAKNHASVTVVVDPADYAVVLDELAAN
                     GETSYETRQRLAAKVFRHTAAYDALIAEYFTAQVGENKPEKLTLTYDLKQPMRYGENP
                     QQDADFYQKALPTDYSIASAKQLNGKELSFNNIRDADAAIRIIRDFKDSPTVVALKHM
                     NPCGIGQADDIETAWDYAYESDPVSIFGGIVVLNREVDAATAEKMHGVFLEIIIAPSY
                     TDEALAILINKKKNLRILALPFNAQEASEVEAEYTGVVGGLLVQNQDVVKESPADWQV
                     VTKRQPTETEATALEFAWKAIKYVKSNGIIVTNDHMTLGVGPGQTNRVASVRLAIDQA
                     KDRLDGAVLASDAFFPFADNVEEIAKAGIKAIIQPGGSVRDQESIEAADKYGLTMVFT
                     GVRHFRH"
     gene            19607..20869
                     /gene="purD"
                     /locus_tag="VQU30_000517"
     CDS             19607..20869
                     /gene="purD"
                     /locus_tag="VQU30_000517"
                     /EC_number="6.3.4.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000772208.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylamine--glycine ligase"
                     /protein_id="HET2446686.1"
                     /translation="MKLLVVGSGGREHAIAKKLLESKDVEKVFVAPGNDGMTLDGLEL
                     VNISISEHSKLIDFAKTNDVAWTFIGPDDALAAGIVDDFNQAGLKAFGPTRAAAELEW
                     SKDFAKEIMVKYGVSTAAYGTFSDFEEAKAYIEKHGAPIVVKADGLALGKGVVVSETV
                     EQAVEAAHEMLLDNKFGDSGARVVIEEFFEGEEFSLFAFVNGDKFYIMPTAQDHKRAY
                     DGDKGPNTGGMGAYAPVPHLPQSVVDTAVDTIVKPVLEGMIKEGRPYLGVLYAGLILT
                     ADGPKVIEFNARFGDPETQIILPRLTSDFAQNITDILDSKEPNITWTDKGVTLGVVVA
                     SKGYPLNYSKGVELPVKTDGDIITYYAGAKFAENSRALLSNGGRVYMLVTTADTVKEA
                     QASIYQELSQQKIEGLFYRTDIGSKAIK"
     gene            21272..21760
                     /gene="purE"
                     /locus_tag="VQU30_000518"
     CDS             21272..21760
                     /gene="purE"
                     /locus_tag="VQU30_000518"
                     /EC_number="4.1.1.21"
                     /EC_number="5.4.99.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000805607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-(carboxyamino)imidazole ribonucleotide mutase"
                     /protein_id="HET2446687.1"
                     /translation="MKPVISIIMGSKSDWATMQKTAEVLDRFGVAYEKKVVSAHRTPD
                     LMFKHAEEARSRGIKIIIAGAGGAAHLPGMVAAKTTLPVIGVPVKSRALSGVDSLYSI
                     VQMPGGVPVATMAIGEAGATNAALFALRLLSVEDKSIADALANFAEEQGKIAEESSNE
                     LI"
     gene            21747..22838
                     /gene="purK"
                     /locus_tag="VQU30_000519"
     CDS             21747..22838
                     /gene="purK"
                     /locus_tag="VQU30_000519"
                     /EC_number="6.3.4.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000099033.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-(carboxyamino)imidazole ribonucleotide
                     synthase"
                     /protein_id="HET2446688.1"
                     /translation="MSSSKTIGIIGGGQLGQMMAISAIYMGHKVIALDPAADCPASRV
                     AEIIVAPYNDVDALRQLADRCDVLTYEFENVDADGLDAVIKDGQLPQGTDLLRISQNR
                     IFEKDFLSNKAQVTVAPYKVVTSSLDLADIDLSKNYVLKTATGGYDGHGQKVIRSEAD
                     LEAAYALADSADCVLEEFVNFDLEISVIVSGNGKEVTFFPVQENIHRNNILSKTIVPA
                     RISESLADKAKAMAVRIAEQLNLSGTLCVEMFATDDDVIVNEIAPRPHNSGHYSIEAC
                     DFSQFDTHILGVLGAPLPVIKLHAPAVMLNVLGQHVEAAEQYVTENSSAHLHMYGKIE
                     AKHNRKMGHVTLFSDVPDSVDELGEGIDF"
     gene            22848..23075
                     /locus_tag="VQU30_000520"
     CDS             22848..23075
                     /locus_tag="VQU30_000520"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006270103.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylaminoimidazole carboxylase"
                     /protein_id="HET2446689.1"
                     /translation="MIQIIVNTFIEKDKTGAVVEVLYASADQDKVQAKYEELAAQYPE
                     NYLAIYDVPLDTDLNTLDHYPSVFIEKEEFE"
     gene            23138..24436
                     /gene="purB"
                     /locus_tag="VQU30_000521"
     CDS             23138..24436
                     /gene="purB"
                     /locus_tag="VQU30_000521"
                     /EC_number="4.3.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000572899.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenylosuccinate lyase"
                     /protein_id="HET2446690.1"
                     /translation="MINRYSRPEMANIWSEENKYRAWLEVEILSDEAWAELGEIPKED
                     VALIRKKADFDIDRILEIEQETRHDVVAFTRAVSETLGEERKWVHYGLTSTDVVDTAY
                     GYLYKQANDIIRRDLENFTNIIADKAKEHKFTIMMGRTHGVHAEPTTFGLKLATWYSE
                     MKRNIERFEHAAAGVEAGKISGAVGNFANIPPFVEEYVCDKLGIRAQEISTQVLPRDL
                     HAEYFAVLASIATSIERMATEIRGLQKSEQREVEEFFAKGQKGSSAMPHKRNPIGSEN
                     MTGLARVIRGHMITAYENVALWHERDISHSSAERIITPDTTILIDYMLNRFGNIVKNL
                     TVFPENMIRNMNSTFGLIFSQRAMLTLIEKGMTREQAYDLVQPKTAYSWDNQVDFKPL
                     LEADSEVTSRLTQEEIDEIFNPVYYTKRVDDIFERLGLGD"
     gene            complement(24491..28429)
                     /gene="strH"
                     /locus_tag="VQU30_000522"
     CDS             complement(24491..28429)
                     /gene="strH"
                     /locus_tag="VQU30_000522"
                     /EC_number="3.2.1.52"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000679939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-N-acetylhexosaminidase"
                     /protein_id="HET2446691.1"
                     /translation="MKHEKQQRFSIRKYAVGAASVLIGFAFQAQTVAADGVTPTTTEN
                     QPTIHTVSDSPQSSENRTEETPKAELQPEAPKTVETETPATDKVASLPKTEEKPQEEV
                     SSTPSDKAEVVTPTSAEKETANKKAEEASPKKEEAKEVDSKESNTDKTDKDKPAKKDE
                     AKAEDDKPETEAGKERAATVNEKLAKKKIVSIDAGRKYFSPEQLKEIIDKAKHYGYTD
                     LHLLVGNDGLRFMLDDMSITANGKTYASDDVKRAIEKGTNDYYNDPNGNHLTESQMTD
                     LINYAKDKGIGLIPTVNSPGHMDAILNAMKELGIQNPNFSYFGKESARTVNLDNEQAV
                     AFTKALIDKYAAYFAKKTEIFNIGLDEYANDATDAKGWSVLQADKYYPNEGYPVKGYE
                     KFIAYANDLARIVKSHGLKPMAFNDGIYYNSDTSFGSFDKDIIVSMWTGGWGGYDVAS
                     SKLLAEKGHQILNTNDAWYYVLGRNADGQGWYNLDQGLNGIKNTPITSVPKTEGADIP
                     IIGSMVAAWADTPSARYSPSRLFKLMRHFANANAEYFAADYESAEQTLNEVPKDLNRY
                     TAESVAAVKEAEKAIRSLDSNLSRAQQDTIDQAIAKLQETVNNLTLTPEAQKEEEAKR
                     EVEKLAKNKVISIDAGRKYFTLNQLKRIVDKASELGYSDVHLLLGNDGLRFLLDDMTI
                     TANGKTYASDDVKKAIIEGTKAYYDDPNGTALTQAEVTELIEYAKSKDIGLIPAINSP
                     GHMDAMLVAMEKLGIKNPQAHFDKVSKTTMDLKNEEAMNFVKALIGKYMDFFAGKTKI
                     FNFGTDEYANDATSAQGWYYLKWYQLYGKFAEYANTLAAMAKERGLQPMAFNDGFYYE
                     DKDDVQFDKDVLISYWSKGWWGYNLASPQYLASKGYKFLNTNGDWYYILGQKPEDGGG
                     FLKKAIENTGKTPFNQLASTKYPEVDLPTVGSMLSIWADRPSAEYKEEEIFELMTAFA
                     DHNKDYFRANYNALREELAKIPTNLEGYSKESLEALDAAKTALNYNLNRNKQAELDTL
                     VANLKAALQGLKPAATHSGSLDENEVAANVETRPELITRTEEIPFEVIKKENPNLPAG
                     QENIITAGVKGERTHYISVLTENGKTTETVLDSQVTKEVINQVVEVGAPVTHKGDESG
                     LAPTTEVKPRLDIQKEEIPFTTVTRENPLLLKGKTQVITKGVNGHRSNFYSVSTSADG
                     KEVKTLVNSVVAQEAVTQIVEVGTMVTHVGDENGQAAIAEEKPKLEIPSQPAPSTAPA
                     EESKALPQDPAPVVIEKKLPETGTHDSAGLVVAGLMATLAAYGLTKRKED"
     gene            complement(28744..29460)
                     /locus_tag="VQU30_000523"
     CDS             complement(28744..29460)
                     /locus_tag="VQU30_000523"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001007200.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HET2446692.1"
                     /translation="MAIPKYQYIKDELKNKIISGQFSSGDKFYTEAELISMYDVSSIT
                     VVRALNDLAKDGYIVRQQGKGTFVSRARKHKLVEFSDIELFNAKDDKVTVLSIERGNK
                     LVYLEKLGLRGDQFYYKIERIRESNGVVYIYHTSYIPEQYINANYPNLEYYSSIYNRF
                     KLDYHIHMNDEHFEEINEIVFPTPEHAASVLGVDEQFPTVLQTKITKLESTGQVLEYS
                     ETYKRSDYYKIKFISCDRDH"
     gene            29808..31595
                     /locus_tag="VQU30_000524"
     CDS             29808..31595
                     /locus_tag="VQU30_000524"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004262529.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-galactosidase"
                     /protein_id="HET2446693.1"
                     /translation="MTRFEIRDDFYLDGKSFKILSGAIHYFRVPPEDWYHSLYNLKAL
                     GFNTVETYVAWNLHEPREGEFHFEGDLDLEKFLQIAQDLGLYAIVRPSPFICAEWEFG
                     GLPAWLLTKNMRIRSSDPVYIEAVGRYYDQLLPRLVPRLLDNGGNILMMQVENEYGSY
                     GEDKAYLRAIRQLMEECGVTCPLFTSDGPWRATLKAGTLIEEDLFVTGNFGSKAPYNF
                     SQMQEFFDEHGKKWPLMCMEFWDGWFNRWKEPIITRDPKELADAVREVLEQGSINLYM
                     FHGGTNFGFMNGCSARGTLDLPQVTSYDYDALLDEEGNPTAKYLAVKKMMATHFSEYP
                     QLEPLYKESMELDAIPLVEKVSLFETLDSLSSPVESLYPQKMEELGQSYGYLLYRTET
                     NWDAEEERLRIIDGRDRAQLYVDGQWVKTQYQTEIGEDIFYQGKKKGLSRLDILIENM
                     GRVNYGHKFLADTQRKGIRTGVCKDLHFLLNWKHYPLPLDNPEKIDFSKGWTQGQPAF
                     YAYDFTVEEPKDTYLDLSEFGKGVAFVNGQNLGRFWNVGPTLSLYIPHSYLKEGANRI
                     IIFETEGQYKEEIHLTRKPTLKHIKGENL"
     gene            31592..32068
                     /locus_tag="VQU30_000525"
     CDS             31592..32068
                     /locus_tag="VQU30_000525"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006155184.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system
                     mannose/fructose/N-acetylgalactosamine-transporter subunit
                     IIB"
                     /protein_id="HET2446694.1"
                     /translation="MTIVGCRIDGRLIHGQVANLWAGKLNVSRIMVVDDEVVNNDIEK
                     SGLKLATPPGVKLSILPVEKAAANILAGKYDSQRLFIVARKPDRFLGLVEAGVPLETL
                     NVGNMSQTPETRSITRSINVVDKDVEDFHKLAEKGVKLTAQMVPNDPISDFLSLLK"
     gene            32096..33001
                     /locus_tag="VQU30_000526"
     CDS             32096..33001
                     /locus_tag="VQU30_000526"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006149155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS
                     mannose/fructose/sorbose/N-acetylgalactosamine transporter
                     subunit IIC"
                     /protein_id="HET2446695.1"
                     /translation="MIQWWQILLLTLYSAYQICDELTIVSSAGSPVFAGFITGLIMGD
                     VTTGLLIGGNLQLFVLGVGTFGGASRIDATSGAVLATAFSVSQGIDAPLAITTIAVPV
                     AALLTYFDVLGRMTTTFFAHRVDAAIERFDYKGIERNYLLGAIPWALSRALPVFFALA
                     FGGAFVQSVVDFVEAYKWVADGLTLAGRMLPGLGFAILLRYLPVKRNLHYLAMGFGLT
                     AMLTVLYSYVTGLGGAVAGIVGTLPAEVAEKIGFVNNFKGLSMIGISIVGIFLAVLHF
                     KNSQKVAVAAPSTPSESGEIEDDEF"
     gene            32988..33803
                     /locus_tag="VQU30_000527"
     CDS             32988..33803
                     /locus_tag="VQU30_000527"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000185291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose/fructose/sorbose transporter family
                     subunit IID"
                     /protein_id="HET2446696.1"
                     /translation="MTNSNYKLTKEDFNQINKRSLFTFQLGWNYERMQASGYLYMILP
                     QLRKMYGDGTPELKEMMKVHTQFFNTSPFFHTIIAGFDLAMEEKDGVGSKDAVNGIKT
                     GLMGPFAPLGDTIFGSLVPAIMGSVAATMAIAGQPWGIFLWIAVAVAYDIFRWKQLEF
                     AYKEGVNLINNMQSTLTALIDAASVLGVFMMGALVATVINFEISYKLPIGEKMIDFQD
                     ILNQIFPRLLPAIFTAFIFWLLGKKGMNSTKAIGIIIVLALALSALGHFALGM"
     gene            33810..34214
                     /locus_tag="VQU30_000528"
     CDS             33810..34214
                     /locus_tag="VQU30_000528"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007284837.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HET2446697.1"
                     /translation="MTKSLILVSHGRFCEELRGSTEMIMGPQDNIYTVALLPEDGPEE
                     FTAKFEAVIEGLDDFLVFADLLGGTPCNVVSRLIMEGRDIDLYAGMNLPMVIEFINAS
                     LTGADADYKSRAAESIVKVNDLLAGFDDDEDE"
     gene            34513..35679
                     /locus_tag="VQU30_000529"
     CDS             34513..35679
                     /locus_tag="VQU30_000529"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004257942.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HET2446698.1"
                     /translation="MLHYTKEDLLELGAEITTREIYQQPDVWREAFEFYQAKREEIAA
                     FLQEIADKHDYIKVILTGAGTSAYVGDTLLPYFKEVYDERKWNFNAIATTDIVAKPAT
                     YLKKDVATVLVSFARSGNSPESVATVDLAKSLVDELYQVTITCAADGKLALQAHGDDR
                     NLLLLQPAVSNDAGFAMTSSFTSMMLTTLLVFDPTEFAVKSERFEVVSSLARKVLDKA
                     EDVKELVDLDFNRVIYLGAGPFFGLAHEAQLKILELTAGQVATMYESPVGFRHGPKSL
                     INDNTVVLVFGTTTDYTRKYDLDLVREVAGDQIARRVVLLSDQAFGLENVKEVVLGCG
                     GVLNDIYRVFPYIVYAQLFALLTSLKVENKPDTPSPTGTVNRVVQGVIIHEYQK"
     gene            35795..36832
                     /locus_tag="VQU30_000530"
     CDS             35795..36832
                     /locus_tag="VQU30_000530"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000649444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactose mutarotase"
                     /protein_id="HET2446699.1"
                     /translation="MKAYTERVFGNVEGEDVLAYRFETDGGYQLEVMTYGATILRYVA
                     PDKAGNFANVILGFDDFDSYVGNSPKHGASVGPVAGRIAGATFELNGKTYDLEVNNAS
                     NCNHSGSTGWDSSLFEVEEVSDHGLTLYTERTDGTGGFPGNLKIWISYHLEETGAYEI
                     SYKVTTDQDTLVNPTNHSYFNLSGDFTQTIDRHVFQLNTEGIYSIAPDGVPAKTPEAN
                     RDVVKHIYNGALLKDIFAEEDEQIQLASGLDHPFALPAGHDNAGFLYDQNSGRFLLFK
                     TEAPCFVVYTANFVDESVIIGGQPMLQHNGIALEAQALPDAIHSDLKGQVILKAGQTF
                     TSKTRYELVVK"
     gene            37040..37894
                     /locus_tag="VQU30_000531"
     CDS             37040..37894
                     /locus_tag="VQU30_000531"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000220702.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HET2446700.1"
                     /translation="MTYEYKSHIYLAETALNVKDLASQTAFYQQVIGLEILSQTETES
                     ILGLGGKVLVQLIQAQESGEVREYYGLYHLAILLPTRKALADVLKHLTDLQIPLVGGA
                     DHGYSEAIYLEDLEGNGIELYRDKPVSTWDIREDGRIIGVTEALAAQDIYELGERVEP
                     FILAEGTRMGHIHLSVKDSRKSSQFYQKVLGLEDKFSVPSASWIAAGDYHHHLAVNEW
                     GGKGLASRKQGLPGLAYYVIEVAHKKELLTIAQRAQEVDAPIKWMTSSQLEITDSDGI
                     VTRIRLAR"
     gene            38044..38301
                     /locus_tag="VQU30_000532"
     CDS             38044..38301
                     /locus_tag="VQU30_000532"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001845567.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-sensitive transcriptional regulator"
                     /protein_id="HET2446701.1"
                     /translation="MTNSKYITCLKRSEGQLCGIQKMIEGDRDCADIVTQLTAVRSSV
                     ERVIEMIITENLTECINQPLDDSEAQKERLEKAIRYLIKRK"
     gene            complement(38677..38769)
                     /locus_tag="VQU30_000533"
                     /pseudo
     CDS             complement(38677..38769)
                     /locus_tag="VQU30_000533"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820552.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus and C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopyranose mutase"
     gene            complement(38805..39101)
                     /locus_tag="VQU30_000534"
     CDS             complement(38805..39101)
                     /locus_tag="VQU30_000534"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000450185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-like domain-containing protein"
                     /protein_id="HET2446702.1"
                     /translation="METSISMADFYGKYQNENLELIDVREAHEFQAGHAPGAKNLPLS
                     TLEQGYKELKPDHEYYVICQGGVRSASTCQFLISQGLTVTNVEGGMNAWPGQVE"
     gene            complement(39091..39252)
                     /locus_tag="VQU30_000535"
     CDS             complement(39091..39252)
                     /locus_tag="VQU30_000535"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014932007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(FAD)-dependent dehydrogenase"
                     /protein_id="HET2446703.1"
                     /translation="MDKKQAYIVSCHSGLRSYIAEPILKQAGFTAQNLDGAYSLYKMV
                     NPEGVEYGN"
     gene            39322..40086
                     /locus_tag="VQU30_000536"
     CDS             39322..40086
                     /locus_tag="VQU30_000536"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862814.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside phosphorylase"
                     /protein_id="HET2446704.1"
                     /translation="MIQKHAIPILEFDDNPQAVIMPNHEGLDLQLPKKCVYAFLDEEI
                     DRYAREVGADCVGEFVSATKTYPVYVINYKGEEVCLAQAPVGSAPAAQFMDWLIGYGV
                     EQIISTGTCGVLADIEENAFLVPVRALRDEGASYHYVAPSRYMEMQPEAIAAIEEVLE
                     DRGIPYEEVMTWTTDGFYRETAEKVAYRKEEGCAVVEMECSALAAVAQLRGVLWGELL
                     FTADSLADLDQYDSRDWGSEAFNKALELSLASVHHL"
     gene            40699..42078
                     /locus_tag="VQU30_000537"
     CDS             40699..42078
                     /locus_tag="VQU30_000537"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000897732.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TrkH family potassium uptake protein"
                     /protein_id="HET2446705.1"
                     /translation="MLFKLSKEKIELGLSRLSPARRIFLSFALVILLGSLLLSLPFVQ
                     VESSRATYFDHLFTAVSAVCVTGLSTLPVAHTYNIWGQIICLLLIQIGGLGLMTFIGV
                     FYIQSKQKLSLRSRATIQDSFSYGETRSLRKFVYSIFLTTFLVESLGAILLSFRLIPQ
                     LGWGRGLFSSIFLAISAFCNAGFDNLGSTSLFAFQTDLLVNLVIAGLIITGGLGFMVW
                     FDLAGHVGRKKKGRLHFHTKLVLLLTIGLLLFGTATTLFLEWNNAGTIGNLPVADKVL
                     VSFFQTVTMRTAGFSTIDYTQAHPVTLLIYILQMFLGGAPGGTAGGLKITTFFVLLVF
                     ARSELLGLPHANVARRTIAPRTVQKSFSVFIIFLMSFLIGLILLGITAKGNPPFIHLI
                     FETISALSTVGVTANLTPDLGKLALSVIMPLMFMGRIGPLTLFVSLADYHPEKKDMIH
                     YMKADISIG"
     gene            42092..42757
                     /locus_tag="VQU30_000538"
     CDS             42092..42757
                     /locus_tag="VQU30_000538"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001283913.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TrkA family potassium uptake protein"
                     /protein_id="HET2446706.1"
                     /translation="MSDRTIGILGLGIFGSSVLAALAKQDMNIIAIDDHAERINQFEP
                     VLARGVIGDITDEELLRSAGIDTCDTVVVATGENLESSVLAVMHCKSLGVPTVIAKVK
                     SQTAKKVLEKIGADSVISPEYEMGQSLAQTILFHNSVDVFQLDKNVSIVEMKIPQSWA
                     GQSLSKLDLRGKYNLNILGFREQENSPLDVEFGPDDLLKADTYILAVINNQYLDTLVA
                     LNS"
     gene            42871..42966
                     /locus_tag="VQU30_000539"
                     /pseudo
     CDS             42871..42966
                     /locus_tag="VQU30_000539"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820552.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus and C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopuranose mutase"
     gene            43112..43561
                     /locus_tag="VQU30_000540"
     CDS             43112..43561
                     /locus_tag="VQU30_000540"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000771906.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HET2446707.1"
                     /translation="MKLLSIAISSYNAAAYLHYCVESLVIGGEQVGILIINDGSQDQT
                     QEIAECLASKYPNIVRAIYQENKCHGGAVNRGLAEASGRYFKVVDSDDWVDPRAYLKI
                     LETLQELESKGQEVDAFVTNFVYEKEGQSRKKSMSYESVLPVRQIFD"
     gene            43718..44128
                     /locus_tag="VQU30_000541"
     CDS             43718..44128
                     /locus_tag="VQU30_000541"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004262849.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl transferase family 2"
                     /protein_id="HET2446708.1"
                     /translation="MYYLPVDFYRYLIGREDQSVNEQVMIKRIDQQLKVNRLLVDQLD
                     LSQVSHPKMREYLLNHIEITTVISSTLLNRSETAEHLAKKRQLWTYIQQKNPEVFQAI
                     RKTMLSRLTKHSVLPDRKLSNVVYQITKSVYGFN"
     gene            44244..>45159
                     /gene="pavB"
                     /locus_tag="VQU30_000542"
     CDS             44244..>45159
                     /gene="pavB"
                     /locus_tag="VQU30_000542"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000671444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fibronectin-binding SSURE repeat adhesin PavB"
                     /protein_id="HET2446709.1"
                     /translation="MKFNPNQRYTRWSIRRLSVGVASVVVASGFFVLVGQPSSVRADV
                     VNPTPGQVLPEETSGTKEGDLSEKPGDTVLTQAKPEGVTGNTNSLPTPTERTEVSEET
                     NSSSLDTLFEKDEEAQKNPELTDVLKETVDTADVDGTQASPAETTPEQVKGGVKENTK
                     DSIDVPAAYLEKAEGKGPFTAGVNQVIPYELFAGDGMLTRLLLKASDNAPWSDNGTAK
                     NPALPPLEGLTKGKYFYEVDLNGNTVGKQGQALIDQLRANGTQTYKATVKVYGNKDGK
                     ADLTNLVATKNVDININGLVAKETVEKAV"
BASE COUNT        12581 a         8714 c        10654 g        13210 t
ORIGIN      
        1 aacatatata cggcaaggcg acgttgacgt ggtttgaaga gattttcgaa gagtgttaga
       61 aaatgccgat aagggtctgc ataccaagag tggtgaggat gatggcaatc cagcagatgg
      121 ctccaagaag aatggatttt ccactggatt tgaccatagc gaccagattg gttttgagac
      181 cgatagcact catggccatg acaataagga atttagagag ttctttgaga ggggtaaaga
      241 aactactgga cacacctaga gaggtgagta gtgtagtgag gagagaggca aggataaagt
      301 aaaggataaa aagtgggaag acttttttca gttgtaggct ttgcttgttt tcttgttggc
      361 gactttgcca gtaggagaga aagagcgtga tagggataat agccaaagta cgtgtgagtt
      421 taacaatggt tgcagactcg agggtattgc tttggtaaag actgtcccaa gcgctggcgg
      481 cagccgttac agaggaagtg tcgttgaccg cagtccctgc aaagagggcg aagccttcat
      541 tggatagatg aagccaggtg ccgagggttg gaaagatgag cgcagccaag acattgaaga
      601 aaaagataac ggaaatggct tgggctactt ccttttcctt agcatcaata acgggcgctg
      661 tcgctgcaat ggcagaaccc ccacagatag aagaacctac tccaaccaag gtagccagtt
      721 ttgtatccag tgcaaagaaa cgctggaaga ggtaggcaat aatcagagct attgagatag
      781 tggacaggat gacagggagt gaagattggc caactgcgaa gacctgcgag atattgagac
      841 caaaaccaag caagacaacg gcatattgga gcaacttctt ggaactaaag gtcaaaccag
      901 catccagttg tttataggac gagagaaagg gatgtaggag catgcctatg aaaatggcaa
      961 aaacgggcgc gccaatcaca gggaagaatc ctcctaagta ccaagatacg atagaaatga
     1021 gaaggcaggc caagatacct gctccatttt ttgatagaaa tgacataaaa acctccaaat
     1081 aaaatctatt accattatag acctataaac aggaaaagta aaatagaaag tggaaagcta
     1141 ttctctaatg tatttttgcg gtcggggggc ttttgtagta taatagagat acgttttgaa
     1201 agtaggaggt atctatggac ttaactaagc gctttaataa acagttagat aaaattcaag
     1261 tttcgttgat tcgtcagttt gaccaggtta tttcggagat tcctggggtc ttgcgtttga
     1321 ccttggggga acctgatttt acaacgccag accatgtcaa ggaggcggcc aagcgagcga
     1381 ttgatcagaa ccaatcctac tatacaggga tgagtggtct gctgactcta cgtcaggcag
     1441 ccagtgactt tgttaaggaa aagtaccaac tggactatgc tcctgaaaat gaaattttgg
     1501 ttacaattgg ggcgacagag gctttatctg cgactttgac ggctattttg gaagagggag
     1561 acaaggtact tttgccagct cctgcttatc caggctatga accgattgtt aacttagttg
     1621 gggcagaaat tgttgagatt gatacgactg aaaatggttt tgtcttgact cctgagatgt
     1681 tggagaaggc cattttggag cagggtgata agctcaaggc ggttattctc aactatccag
     1741 ccaatccgac aggaattacc tacagtcgag agcagttaga ggccttggca gctgttttac
     1801 gcaagtacga aatttttgtt gtctgtgatg aggtttactc agaattgacc tacacaggcg
     1861 aagcccatgt gtctctagga acgatgttga gagaccaggc tattattatc aatggtttgt
     1921 ctaaatcgca tgccatgaca ggttggcgtt tggggctgat tttcgctcct gcggccttca
     1981 cagcccagtt aatcaagagt caccaatact tggtcactgc cgcaaatacc atggcgcaac
     2041 atgctgcggt agaagccttg acggctggta aaaatgatgc ggagcccatg aagaaggaat
     2101 atatccaacg tcgggactat atcatcgaaa aaatgactgc tcttggtttt gagattatca
     2161 aaccagacgg tgccttctat atttttgcta aaattccagc gggctacaat caagactcct
     2221 ttgcttttct gaaggatttt gctcagaaga aggccgttgc ctttatccct ggtgcagcct
     2281 ttggacgtta cggggaaggc tacgtccgcc tatcttatgc agccagcatg gagactatca
     2341 aagaagccat gaaacgactt gaggagtaca tgagagaagc atgattcagt ctatcacgag
     2401 tcaaggcttg gtgctttaca atcgcaattt tcgtgaggat gacaagctcg tcaaaatttt
     2461 tacagagcag gttggcaaac gcatgttttt tgtcaaacac gctggtcagt ctaagctggc
     2521 gcctgttatt cagcccttgg tgctggcacg atttctcttg cgaatcaatg atgacggact
     2581 cagttacatc gaagactatc atgaggtcat gacttttccc aagattaata gtgacctctt
     2641 tgtcatggcc tatgcgacct atgtggcagc tcttgcagat gctagtttgc aggacaatca
     2701 gcaggatgct cccttgtttg cttttttgca aaagactttg gagttgatgg aagcaggctt
     2761 ggattatcag gttttgacca atatttttga aattcaaatt ttgactcgat ttggaatcag
     2821 cctcaatttt aatgagtgtg tcttctgcca tcgggttggt caggcttttg acttttcttt
     2881 caaatatgga gcctgcctct gtccagagca ttatcatgag gataagagac gttgtcatct
     2941 caatcccaat atcccctatc tgctcaatca atttcaagct attgattttg agactttgga
     3001 gaccatttcg ctcaagcctg gaatcaagca agagctacgc caatttatgg atcaattata
     3061 tgaagagtac gttgggattc acctaaaatc aaagaaattt attgattccc tagcagactg
     3121 gggacaatta ctaaaagagg aaaagaaatg aaaaaaatcg cagtagatgc catggggggc
     3181 gattacgcac ctcaggccat tgttgagggt gtcaatcaag ccctatctga cttttcagat
     3241 atcgaggttc aactttacgg agatgaagct aaaatcaagc aatatctgac agcgacagag
     3301 cgcgtcagca ttatccatac ggatgagaag attgattcgg atgatgaacc tacgagagct
     3361 attaggaata agaaaaatgc cagtatggta ttggcagcca aggctgtcaa agatggtgaa
     3421 gcagacgctg tcctttcggc tgggaataca ggtgccttgt tggcagcagg attcttcatc
     3481 gtgggtcgta tcaagaatat cgaccgtcct ggactcatgt ctaccttgcc taccgttgat
     3541 ggaaaaggtt ttgacatgct agaccttggt gccaatgcag aaaatacagc ccagcacctc
     3601 catcaatatg cggttctagg ttccttctat gctaaaaatg tccgtggcat tgcgcaacca
     3661 cgcgttggtt tgctcaacaa cggaacagag agtagcaagg gcgacccgct tcgtaaggaa
     3721 acttatgaat tactggcggc tgatgaaagt ttgaacttta tcggaaacgt ggaagcgcgt
     3781 gatttgatga atggcgttgc agatgttgtt gtggcagatg gtttcacggg aaacgctgtg
     3841 ctcaaatcca tcgaagggac agctatggga atcatgggct tgctcaagac agctattaca
     3901 ggtggtggtc ttcgagcgaa actaggtgcc ctccttctca aggacagcct cagaggtttg
     3961 aaaaaacagc tcaattattc agatgttggt ggagcggtct tgtttggtgt taaggcacct
     4021 gttgtcaaga ctcatggctc aagcgatgcc aaggctgttt atagtacgat tcgtcagatc
     4081 cgtaccatgc tagaaacaga cgtggttgcc cagactgcgc gtgaattttc aggagaataa
     4141 aagagatgac agaaaaagaa atttttgacc gtattgtgac cattatccaa gagcgacagg
     4201 gagaggactt tgtcgtgaca gaatccttga gtctgaaaga cgatttggat gcggattctg
     4261 ttgacttgat ggagtttatc ttgactctgg aagatgaatt tagtatcgaa atcagcgatg
     4321 aggaaattga ccaactccaa agtgtaggag atgtggttaa aatcattcaa ggaaaatagc
     4381 aatcggagtt ccaagtcaac ggaagtagat ggtttttaga aatgagaaat atcggacaag
     4441 ctggtaaaat cttggctgac agtggttatc aagggctcat gaagatatat cctcaagcac
     4501 aaacttccac gtaaatccag caaactcaag ccgctaacag ttgaagataa agcctgtaat
     4561 catgcgctat ctaaggagag aagcaaggtt gagaatatct ttgccaaagt aaaaacgttt
     4621 aaaatgtttt caacaaccta tcgaaatcat cgtaaacgct tcggattacg aatgaatttg
     4681 attgctggta ttatcaatca tgaactagga ttctagtttt gcaggaagtc taatagtaaa
     4741 aaagtgatta gaaaacatct tttttaaaaa tagagatgat tttgaaacaa aaaagctaat
     4801 tcaagacgtt tcgatgccaa ttcaagattt ggatgaaaaa aattaataga tactgttata
     4861 ctaaacttgt caagtttgta acaagacaaa tattaaaaat aaaaaagagg tattcgttat
     4921 gaatacaaaa aagatgtcac aatttgaaat tatggatact gagatgcttg cttgcgttga
     4981 aggtggcgga tgcaattggg gagattttgc caaagcaggt gttggaggag gagcagtacg
     5041 aggtcttcag ctaggaatta aaacaagaac atggcaaggt gcagcaactg gtgctgcggg
     5101 aggagctata cttggaggtg tggcctatgc agcgacatgt tggtggtaat tatggatttt
     5161 aaaagtttta ttattggttt agtagttggt atatttggtc cttatatgga tgatttaatt
     5221 agaaaaaaat ttttaaagtc ttcggagaag aaaacagaaa aatctgttaa aaaataatca
     5281 aaactataaa tgatgaatct gaatcaaaat tattttgcgc atgtaaagag gagtcttata
     5341 gtaacgagtc aaaaaaggag taactatgaa tcgtaattta gaacggtgtt atctattctg
     5401 actaggaata gatcatacca gaggtagctt agaaatagca gggacattag aaattgaagt
     5461 aataaatagg atgtcgtaag tgttactatc aatgatttat ttgtttcaag cttgcctagg
     5521 gtgacagtaa aaaatcaatt tcctttcaat agcatatttt tagtgggcag gactcttgtt
     5581 ctgcctattt ttttatccaa aaagtgcagt tgggagggag ataggctcat ttgggaagga
     5641 agtccagttt ttgtttagtg attggggtaa gatagttgtt atcagatgag tttatactct
     5701 tcgaaaatca aattcaaacc acgtcaacgt cgccttgccg tatatatgtg actgacttcg
     5761 tcagtcctat ctacaacctc aaaacagtgt tttgagcagc ctgcggctag tttcctagtt
     5821 tgctctttga ttttcattga gtattaggga aaaggagatg aatatgaaat ttgggaaacg
     5881 tcactatcgt ccgcaagtgg atcagatgga ctgcggtgta gcttcattag ccatggtttt
     5941 tggctactat ggtagttatt attttttggc tcacttgcga gaattggcta agacgaccat
     6001 ggatgggacg acggctttgg gcttggtcaa ggtggcagag gagattggtt ttgagacgcg
     6061 agccattaag gcggatatga cgctttttga cttgccggat ttgacttttc cttttgttgc
     6121 ccatgtgctt aaggaaggga aattgctcca ctactatgtg gtgactgggc aggataagga
     6181 tagcattcat attgccgatc cagatcccgg ggtgaagttg actaaactgc cacgtgagcg
     6241 ttttgaggaa gaatggacag gagtgactct ttttatggca cctagtccag actataagcc
     6301 ttataaggaa caaaaaaatg gtctgctctc ttttatccct atattagtga agcagcgtgg
     6361 cttgattgcc aatatcgttt tggcaacact cttggtaacc gggattaaca ttgtgggttc
     6421 ttattatctg cagtctatca ttgataccta tgtgccagat cagatgcgtt cgacactagg
     6481 gattatttct attgggctag tcatcgtcta catcctccag caaatcttgt cttacgctca
     6541 ggagtatctc ttgcttgttt tggggcaacg cttgtcgatt gacgtgattt tgtcctatat
     6601 caagcatgtt tttcacctcc ctatgtcctt ctttgcgaca cgcaggacag gggagatcgt
     6661 gtctcgtttt acagatgcta acagtatcat cgatgcgctg gcttcgacca tcctttcgat
     6721 tttcctagat gtgtcaacgg ttgtcattat ttcccttgtt ctattttcac aaaataccaa
     6781 tctctttttc atgactttat tggcgcttcc tatctacaca gtgattatct ttgcctttat
     6841 gaagccgttt gaaaagatga atcgggatac catggaagcc aatgcggttc tgtcttcttc
     6901 tatcattgag gacatcaacg gtattgagac tatcaagtcc ttgaccagtg aaagtcagcg
     6961 ttaccaaaaa attgacaagg aatttgtgga ttatctgaag aaatccttta cctatagtcg
     7021 agcagagagt cagcaaaagg ctctgaaaaa ggttgcccat ctcttgctta atgtcggcat
     7081 tctctggatg ggggctgttc tggtcatgga tggcaagatg agtttggggc agttgattac
     7141 ctataatacc ttgctggttt actttaccaa tcctttggaa aatatcatca atctgcaaac
     7201 caagcttcag acagcgcagg ttgccaataa ccgtctaaat gaagtgtatc tagtagcttc
     7261 tgagtttgag gagaagaaaa cagttgagga tttgagcttg atgaagggag atatgacctt
     7321 caagcaggtt cattacaagt atggctatgg tcgagacgtc ttgtcggata tcaatttaac
     7381 cgttccccaa gggtctaagg tggcttttgt ggggatttca gggtcaggta agacgacttt
     7441 ggccaagatg atggttaatt tttacgaccc aagtcaaggg gagattagtc tgggtggtgt
     7501 caatctcaat cagattgata aaaaagccct gcgccagtac atcaactatc tgcctcaaca
     7561 gccctatgtc tttaacggaa cgattttgga gaatcttctt ttgggagcca aggaggggac
     7621 gacacaggaa gatatcttac gggcggtcga attggcagag attcgagagg atatcgagcg
     7681 catgccactg aattatcaga cagaattgac ttcggatggg gcagggattt caggtggtca
     7741 acgtcagaga atcgctttgg cgcgtgctct cttgacagat gcgccggtct tgattttgga
     7801 tgaggcgact agcagtttgg atattttgac agagaagcgg attgtcgata atctcatggc
     7861 tttggacaag accttgattt tcattgctca ccgcttgact attgctgagc ggacagagaa
     7921 ggtggttgtc ttggatcagg gcaagattgt cgaagaagga aagcatgctg atttgcttgc
     7981 acagggaggc ttttacgccc atttggtcaa tagctagaaa gaggagagga tgaaaccaga
     8041 atttttagaa agtgcggagt tttataatcg tcgttaccat aatttttcca gtagtgtgat
     8101 tgtacccatg gcccttctgc tcgtgttttt acttggcttt gcaactgttg cagagaagga
     8161 gatgagtttg tccactagag ctactgtcga acccagtcgt atccttgcaa atatccagtc
     8221 aactagcaac aatcgtattc ttgtcaatca tttggaagaa aataagctgg ttaagaaggg
     8281 ggatctcttg gttcaatacc aagaaggggc agagggtgtc caagcggagt cctatgccag
     8341 tcagttggac atgctaaagg atcaaaaaaa gcaattggag tatctgcaaa agagcctgca
     8401 agaaggggag aaccactttc cagaggagga taagtttggc taccaagcca cctttcgcga
     8461 ctacatcagt caagcaggca gtcttagggc tagtacatcg caacaaaatg agaccatcgc
     8521 gtcccagaat gcagcagcta gccaaaccca agccgaaatc ggcaacctca tcagtcaaac
     8581 agaggctaaa attcgcgatt accagacagc taagtcagct atggaaacag gtgcttcctt
     8641 ggccagtcag aatctagcct actctcttta ccagtcctac aagtctcagg gcgaggaaaa
     8701 tccccaaact aaggttcagg cagttgcaca ggttgaagca cagatttctc agttagaatc
     8761 tagtcttgct acttaccgtg tccagtatgc aggttcaggt acccagcaag cctatgcgtc
     8821 agggttaagc agtcaattgg aatcccttaa atcccaacat ttggcaaagg ttggtcagga
     8881 attgaccctt ctagcccaga aaatcttgga ggcagagtca ggtaagaagg tacagggaaa
     8941 tcttttagac aaggggaaaa ttacggcgag tgaggatggg gtgcttcatc ttaatcctga
     9001 gaccagtgat tctagcatgg ttgcagaagg tgccctacta gcccaacttt atccatcttt
     9061 ggaaagagaa gggaaagcca aactcacagc ctatctaagt tcaaaagatg tagcaagaat
     9121 caaggtcggt gattctgttc gctatactac gactcatgat gccgggaatc aacttttcct
     9181 agattctact attacaagta ttgatgcgac agctactaag actgagaaag ggaatttctt
     9241 taaaatcgag gcggagacta atctaacttc ggagcaggct gaaaaactta ggtacggggt
     9301 ggaaggccgc ttgcagatga ttacgggcaa gaaaagttat ctacgttatt atttggatca
     9361 atttttgaac aaagagtaat gttcgtgttt ttagagttaa ataattttta aactgtgaga
     9421 aagattcttc ttgcagtttt ttctttacaa tttttaaaaa aacatctgct atttattcgg
     9481 ttaaattctt gtgttttttg gttttttgtg gtaaaatgtg ctcaagtaat acgaaaggcg
     9541 aactttaaaa tgtcaaaaca attgatctat tcgggaaaag ctaaagatat ctatacaact
     9601 gaggatgaaa atcttattat ttcaacttac aaggaccagg cgactgcttt caacggtgtc
     9661 aagaaggagc agattgcagg taagggagtc ttgaataatc agatctcatc ttttattttt
     9721 gagaaattaa atgcggctgg tgtggcgact cactttgtgg agaaactttc agacacggaa
     9781 caactcaata aaaaggttaa gattattcct ttggaagtcg tgctccgcaa ctatactgct
     9841 ggttcctttt caaaacgttt tggtgtggat gagggaatcg ccttggagac tccgattgtc
     9901 gaattttact acaaaaatga tgatttggat gatccattta tcaatgatga gcatgtgaaa
     9961 ttcctacaga ttgcgggtga ccagcagatt gcctacttga aggaagaaac gcgtcgtatc
    10021 aatgaactat tgaaagtctg gtttgctgag attgggctta aattgattga ctttaagcta
    10081 gagttcggtt ttgacaagga tggcaagatt atcttggcag acgaattttc accagataac
    10141 tgccgcttgt gggacgctga tggcaaccac atggataagg atgttttccg tagaggattg
    10201 ggagaactaa ccgacgttta tgagattgtt tgggaaaagt tgcaggaatt gaaataatct
    10261 gtttgcaacg gaaaaccttc gtctctcaac taaaaggact caggctgaaa aggtccccca
    10321 gaccttttca ctctgtagag aactaggtga actaacagat gtttacgaaa ttgtctggga
    10381 aaagttgcag ggtttaaaat aacaacctca aggctgtttg ggaatattgc aagagctgaa
    10441 ataaaggaat aagaattgat ggataaacgt atttttgttg aaaaaaaggc tgattttcag
    10501 gtcaagtcag agagtttggt tagagagctc cagcacaact tgggactgtc aagcttgaaa
    10561 agtattcgta ttgtgcaagt atatgatgta tttgacttgg ctgaggactt gtttgcacct
    10621 gcagagaagc acattttctc tgagcaggga accgaccatg ttttagatga agtatctgtg
    10681 caggcggatc ttgctaacta tgctttcttt gccattgaaa gtctgccagg gcagtttgac
    10741 cagcgtgcag cttcgtcaca ggaagccttg cttttgttgg gaagttcgag tgacgtgaca
    10801 gtcaacacag cccaacttta cttggtgaat aaagatattg atgcgactga gttggaagct
    10861 gtcaaaaact acctgctcaa tccagttgat tctcgtttca aggatatcac gacagggatt
    10921 gccaagcagg agttttcaga gtcagacaag accattccaa aattgacttt ctttgaaagc
    10981 tatacagcag aagactttgc tcgctacaag gccgagcaag ggatggccat ggaagtggat
    11041 gatttgctct ttatccaaga ctactttaag tcaatcgggc gcgtgccaac tgagactgaa
    11101 ctcaaggttt tggacactta ctggtctgac cactgccgtc atacgacttt tgagacagag
    11161 ttgaaacaca tcgacttttc agcttctaaa tttcaaaagc aattgcagtc aacctatgac
    11221 aagtatattg ccatgcgcga ggagttaggt cggtctgaaa aaccacaaac cttgatggat
    11281 atggcgacta ttttcggtcg ttatgagcgt gctaacggac gattggatga tatggaagtc
    11341 tctgacgaaa tcaatgcctg ctcagttgaa attgaagtgg atgttgatgg tgtcaaggaa
    11401 ccttggctcc tcatgtttaa aaatgaaacc cacaaccatc caacagaaat tgagccattt
    11461 ggtggagcgg ctacctgtat cggtggagct attcgtgatc cgttgtcagg ccgttcctat
    11521 gtttaccaag ccatgcgtat ttcaggtgct ggtgatatta cagcaccgat ttcggaaact
    11581 cgtgctggga aattgccaca acaagtcatt tctaaaacag cagctcatgg ttattcttca
    11641 tatggtaacc agattgggct tgccacaacc tacgttcgtg aatacttcca cccaggcttt
    11701 gtagctaaac gtatggaact tggtgccgtt gttggtgcgg ctcccaaggg caatgttgtc
    11761 cgtgaaaaac ctgaagcagg tgatgtgatc atccttctcg gaggcaaaac aggtcgtgat
    11821 ggtgtcggtg gtgcgacggg ctcttctaag gttcaaacag ttgagtctgt agagactgct
    11881 ggtgctgagg ttcaaaaagg aaatgccatc gaagaacgca agattcagcg cctcttccgt
    11941 aatggcaatg tcactcgtct gatcaagaag tccaatgact ttggggcagg cggcgtctgt
    12001 gtggctatcg gtgaattggc agacggtctt gaaatcgacc tcaacaaggt gcctcttaaa
    12061 taccagggct tgaatggtac agaaattgcc atctctgaat cacaagaacg gatggcggtc
    12121 gtggttcgtc ctgaagatgt ggataccttc gttgccgaat gtaacaaaga aaatattgat
    12181 gctgttgtgg tggcgacagt aactgaaaaa ccaaatcttg tcatgcactg gaatggtgag
    12241 acaatcgttg acttggagcg tcgtttcctt gacaccaatg gtgtgcgcgt ggttgtcgat
    12301 gccaaagttg tggacaagga tgtcaaactc ccagaagagc gtcaaacatc tgctgaaaca
    12361 ctggaatcag atacccttac ggttctatct gacctcaacc atgcaagtca aaaaggatta
    12421 cagactatct ttgactgctc tgttggacgc tcaacggtta atcacccact tggtggtcgt
    12481 taccaactca caccaactga ggcatctgtg cagaaattgc cagttcaaca cggtgtgact
    12541 catactgcgt cggtcattgc tcaaggtttc aacccatatg tagctgaatg gtctccatac
    12601 cacggtgctg cttatgcggt tatcgaagca actgctcgtt tggtggctgc tggtgccaac
    12661 tggtctaagg ctcgtttctc ttaccaagaa tatttcgagc ggatggacaa gcaagcagag
    12721 cgtttcggtc agccagtagc tgctcttcta ggttctattg aagcacaaat tcagcttggc
    12781 ttgccatcta tcggtggtaa ggactccatg tctggtacct ttgaagaatt gaccgttccg
    12841 ccaaccttgg ttgcctttgg ggtgacgacg gcagatagcc gtaaggtgct ctctccagaa
    12901 tttaaagctg ttggggaaaa tatctactac atcccaggtc aagccctctc tgcagagatt
    12961 gattttgact tgattaagaa aaattttgct cagtttgaag caagccaagc tgaccataaa
    13021 gtgacgtctg catcagctgt caaatacggt ggtgtagttg aaagtttggc tcttgctacc
    13081 tttggaaact atattggtgc agaggtgacc ttgcctgaac ttaaaacagc tttgacagct
    13141 caattaggcg gctttgtctt cacatctcct gaagaaattg ctggagtaga gaagattgga
    13201 caaacgaaag cagactttac actgactgtc aacggtgtga agctagatgg acacaagctt
    13261 gacagtgcat ttcaagggac attggaagaa gtttacccaa cagaatttac ccaagcgaaa
    13321 gaactagaag aagtaccagc tgtggcatca gatgttgtga ttaaagccaa agaaaaggtt
    13381 gaaaaacctg tggtttacat cccagtcttt ccaggaacca actcagaata tgattcagct
    13441 aaggccttcg aaaaagaagg tgcagaggtc aatttggtgc cattcgtgac cttgaatgaa
    13501 gaagctattg tcaagtcagt tgaaactatg gttgacaata tcgacaagac taatattctc
    13561 ttctttgccg gtggattctc ggctgcggat gaaccagatg gttcagctaa gtttatcgtc
    13621 aatatcctgc ttaatgaaaa agtgcgtgtg gctattgata gctttatcgc ccgtggtggc
    13681 ttgattatcg gtatttgtaa tggattccaa gccttagtca aatcgggtct cctaccatac
    13741 ggaaactttg aagatgctaa cagtactagt ccaaccctct tctacaatga tgccaaccaa
    13801 cacgtgacca agatggtgga aactcgcatt gccaatacca actcaccatg gttggctggt
    13861 gtgcaagtgg gcgatatcca cgctattcct gtttcgcacg gtgaagggaa gtttgtcgtg
    13921 acggctgagg aatttgcaga gctccgtgac aatggacaaa ttttcagcca atacgttgac
    13981 tttaacggta aaccaagtat ggattctaag tacaatccga atggttctgt ccatgccatc
    14041 gaaggaatta ccagcaagaa tggtcaaatc atcggtaaga tgggccactc agaacgttat
    14101 gaggatggtc ttttccaaaa tatcccaggc aataaagacc aacacctgtt cgcatcagcg
    14161 gttaaacatt tcactggaaa ataagactta cagattttct aatagatagt atcagtaatg
    14221 taaaagtcat gtaaatctag ctcttgatga ttacaaatga aaattaggta taaaaaatga
    14281 catacgaagt aaaatctctt aatgaagaat gtggtgtttt cggtatttgg ggacatccag
    14341 atgctgctaa gttgacctat tttggactcc acagtcttca acaccgtggt caggaggggg
    14401 caggaatcct ctccaatgat caaggacaac tgaagcgcca tcgtgacatg gggcttttat
    14461 cagaagtttt cagaaatcca gccaatttgg ataaattgac aggagctggt gcgattgggc
    14521 atgtgcgtta tgcgactgct ggcgaagctt ctgttgataa catccagccc ttcctcttcc
    14581 gttttcacga tatgcagttt ggcttggctc ataatggaaa tctgaccaat gcagcctctc
    14641 tcaagaaaga actggaacaa agaggagcaa ttttcagcgc gacttcggac tctgaaatct
    14701 tggctcacct cattcgtcgt agtcataatc ctagcctgat gggcaaaatc aaggaagcgc
    14761 tcagccttgt caaaggtggt tttgcctata tcttgctgtt tgaggacaag ttgattgcgg
    14821 ctcttgaccc taatggcttt cgtccgcttt ctatcgggaa aatggccaac ggagcggtgg
    14881 ttgtttcctc tgaaacctgt gcttttgagg tcattggtgc cgagtggatt cgtgatttga
    14941 agccaggtga gattgtgatc attgatgacg agggcattca gtatgacagc tatacagatg
    15001 atactcagtt ggcgatttgt tctatggagt atatctactt tgctcgccct gattctaata
    15061 tccacggtgt caatgtccat acggcacgta agagaatggg agcgcaattg gcgcgagaat
    15121 ttaagcatga ggcagatatt gtagttggtg tgcccaattc ttccctaagc gcggctatgg
    15181 gatttgcgga agaatcaggc ttaccaaatg aaatgggtct gatcaaaaac caatacaccc
    15241 agcgaacttt tatccaaccg actcaagaat tgcgggagca aggagtgcgg atgaaactgt
    15301 ctgctgtttc gggtgttgtc aaaggcaaac gtgtggtcat ggtggatgat tccattgtac
    15361 gtggaacaac ctctcgtcgt atcgttcagc tcttgaaaga agcgggtgcg actgaggttc
    15421 acgttgccat tggaagtcct gcactagcgt atccatgttt ctacgggatt gatatccaga
    15481 cccgtcagga gctgattgca gccaatcata cggtcgaaga aactcgccaa atcattggtg
    15541 cggacagtct gacttatctt tcaattgatg gcttgattga gtcgattggt atcgaaacag
    15601 atgcgccgaa cggtggtctc tgtgtcgctt actttgacgg tgactaccca acgcctctct
    15661 atgactacga agaagactat cgtagaagtt tggaagaaaa gaccagtttt tacaagtagg
    15721 cgacagattc tccattaaag aaaaggaaaa aacaaatgac aaataaaaat gcatatgccc
    15781 agtcgggtgt ggatgttgaa gcgggttatg aagttgttga acggattaaa aagcacgtgg
    15841 cccgtacgga gcgtgcaggt gtcatgggag ctcttggtgg ctttggtggt atgtttgacc
    15901 tttccaagac tggggttaaa gaacccgtct tgatttcagg gactgacggt gtcggaacca
    15961 agctcatgtt ggctatcaag tacgacaagc acgataccat cgggcaggac tgtgtggcca
    16021 tgtgtgtcaa cgacatcatt gctgcaggtg cggaacccct ctattttctc gactacgtag
    16081 cgacagggaa gaatgaacca gctaagctag aacaagtggt tgctggtgtg gcagaaggtt
    16141 gtgtgcaggc tggtgctgcc ctcatcggtg gggaaacggc tgaaatgccg ggcatgtacg
    16201 gcgaagacga ctatgacttg gctggttttg cggtcggtgt ggctgaaaaa tctcaaatca
    16261 ttgacggttc aaaggtggta gagggagatg ttcttctcgg acttgcttca agtgggattc
    16321 actcaaatgg ttactctttg gttcgtcgtg tctttgcgga ttacacaggt gaggaagtcc
    16381 taccagaatt ggaaggcaag aaacttaagg aagttctact tgagccgact cgtatctatg
    16441 tcaaggctgt cttgccgctc atcaaagaag agttggtcaa cggcattgcc cacatcacag
    16501 gtggtggctt tatcgaaaat gtccctcgta tgtttgcaga tgacctagct gctgaaattg
    16561 atgaaagcaa agttccagtg cttccaattt tcaaagccct tgaaaaatat ggtcagatta
    16621 aacacgaaga aatgtttgaa atcttcaata tgggtgtggg acttatgttg gcggtcagcc
    16681 ctgaaaatgt agagcgtgta aaagaattgt tggatgaagc agtctatgaa attggtcgca
    16741 tcgtcaagaa agaaaacgaa agtgtcatta tcaaatgaaa aaaatagcgg tttttgcctc
    16801 tggtaatggc tcaaattttc aggtgattgc cgaagaattt ccagtggagt ttgtcttttc
    16861 agaccatcgt gatgcctatg tgcttgagcg tgcaaagcag ctcggcgttc tgtcctatgc
    16921 ttttgaactc aaggagtttg agagcaaggc agactacgaa gcagcccttg tcgaactctt
    16981 ggaagaacac cagattgcct tggtttgcct agcaggctac atgaaaatcg ttggaccaac
    17041 cttattgtcg gcttatgaag gtcggattgt caacattcat ccagcctact tgccagaatt
    17101 tccaggagct catgggattg aggatgcttg gaatgctggc gtgggtcagt ctggtgtgac
    17161 cattcactgg gtggattcgg gtgtggatac aggccaggtc atcaaacagg ttcgtgtgcc
    17221 acgactagct gatgatacca ttgacagatt tgaagctcgc atccatgaag cagagtacag
    17281 gttgtatccg gaagtagtga aggctctatt tacagattga ctttttgatg attcatatga
    17341 tatctttgat tttaaattgg agtcagtgtt tgttgaagac ggcttcaaac ggaggtattt
    17401 gtaatgttag aatctaaaaa aacaactcga tatgtatttt atgtctatct gatgttatta
    17461 acttggggaa tcttatttaa gtttgaaaca aatcctgaat ttatagcatt tttcttagct
    17521 ccaaggtata tcaattggat tccattttca gaaccactaa tagtcgatgg aaaaattgtt
    17581 tttgctgaaa tgttatttaa tctgattttc tttattccat taggtgtttg tttccctttg
    17641 ataaaaacta atttatctag tttaagaata gtcgggacag gtttcttgat tagtttattg
    17701 tttgagtgct tacagtatat tttagcaata ggtataacag atataacgga tttgacttta
    17761 aatacgctag gtgtctgtgt aggcttactg atttatcaaa tttttataag agtgttcaaa
    17821 tcacagacta gaaaatggat caatatctta ggtatgctta gccttggttt tgcttatctt
    17881 gttttactgt tactgcattt aattggtgtt taactaatga ttaaaaagga gaatataatg
    17941 actaaacgcg tcttaatcag cgtctcagac aaagcggaca ttgttgaatt tgcccaagaa
    18001 ctcaaaaaac ttggttggga gattatctcg acaggtggaa ctaaggttgc ccttgataat
    18061 gctggggtgg ataccattgc tatcgatggt gtgactggtt tcccagaaat gatggacggt
    18121 cgtgtgaaga ccctccaccc aaatatccac ggagggcttc tcgctcgtcg tgacttggat
    18181 agccacttgg aagcggctaa ggacaacaag attgagctca ttgaccttgt ggtggtcaac
    18241 ctttacccat ttaaggaaac tatccttaaa ccagatgtga cttatgatga tgcagttgaa
    18301 aatatcgata ttggtgggcc atctatgctt cgttcagcag cgaaaaatca tgccagtgtt
    18361 acagttgtgg tagatcctgc tgactacgct gtggttttgg acgaattggc agcaaacggc
    18421 gaaacctctt atgaaactcg ccaacgttta gcagccaaag tatttcgtca cacagcggct
    18481 tatgacgcct tgattgcaga atacttcaca gctcaagtgg gtgaaaacaa gcctgaaaaa
    18541 ctcactttga cttatgacct caagcaacca atgcgttacg gtgagaatcc tcaacaagac
    18601 gcggactttt accagaaagc tttgcctaca gactactcca ttgcttcagc caaacagctc
    18661 aacgggaaag aattgtcatt taataatatc cgtgatgcag atgctgctat ccgtatcatc
    18721 cgtgacttca aagatagtcc aaccgttgtg gctctcaaac acatgaatcc atgtggaatt
    18781 ggtcaagctg atgacatcga gactgcttgg gactacgctt atgagtctga cccagtgtct
    18841 atctttggtg ggattgtcgt cctcaaccgt gaggtggatg ctgcgacagc tgagaagatg
    18901 cacggcgttt tcctcgaaat catcattgca ccaagctata cggatgaagc gctagccatt
    18961 ttgatcaata aaaagaaaaa cttgcgtatc cttgccttgc catttaatgc tcaagaggct
    19021 agcgaagtgg aagcagaata cacaggtgta gtcggtggac ttctcgtgca aaatcaagac
    19081 gtggtcaagg aaagcccagc tgactggcaa gtggtgacta aacgtcagcc aactgagaca
    19141 gaagcgactg ctcttgagtt cgcttggaag gctatcaagt acgtcaaatc aaatggtatt
    19201 atcgtgacca acgaccacat gacacttggt gttggtccag gtcaaaccaa ccgtgtggct
    19261 tctgttcgcc ttgccattga ccaagccaaa gatcgtctgg acggggcggt ccttgcttca
    19321 gatgccttct tcccatttgc ggataacgtg gaagaaatcg ccaaagcagg aattaaggcc
    19381 atcatccagc ctggtggctc tgtccgtgac caagaatcca tcgaagcagc ggataaatac
    19441 ggcttgacta tggtctttac aggtgtgaga cattttagac attaagaaga taaaagggaa
    19501 gaaaacagtt tctttccttt tttggcttaa aatgctaact gaaacaagat taaaacgaac
    19561 ttttttgata taatgttggt aaataattcg caaaagaggt tgaggaatga aactgcttgt
    19621 tgtcggttct ggtggtcgtg agcatgcgat tgctaaaaag ttacttgaat caaaagacgt
    19681 ggaaaaagtc tttgtagctc ctgggaatga tgggatgact ctggatggtt tggaattggt
    19741 aaatatctct atttccgaac attctaaatt gattgacttc gcaaagacca atgatgttgc
    19801 ttggaccttt atcggtccag atgatgccct tgctgctggt atcgtggatg attttaacca
    19861 agctgggctt aaggcctttg gtccgactag ggctgcagcg gagctggagt ggtccaagga
    19921 ttttgccaag gaaatcatgg tcaaatatgg tgtttcgaca gcagcctatg gcacattttc
    19981 agatttcgag gaagcaaagg cctatatcga aaagcatggt gcgcctatcg tagtcaaggc
    20041 ggatggcttg gcgcttggga agggtgtcgt cgtttctgag acggttgagc aagcggtcga
    20101 agccgctcat gagatgcttt tggacaataa atttggtgac tcaggtgcgc gcgtggttat
    20161 tgaggaattc tttgaaggag aggaattttc actctttgcc tttgtcaatg gtgataagtt
    20221 ctacatcatg ccaacggctc aggaccacaa acgtgcctat gatggcgaca aagggcctaa
    20281 cacgggtggt atgggtgcct atgcgccagt tccacactta ccacagagtg tagttgatac
    20341 agcggttgac accattgtca agccagttct agaagggatg attaaagaag gtcgccctta
    20401 tctgggagtt ctttacgcag ggcttatcct gacagctgat ggaccgaaag tcattgagtt
    20461 caacgctcgg ttcggagatc cagaaactca gattatcttg cctcgcttaa cctctgactt
    20521 tgctcaaaat atcacagata tcctggatag caaggagcca aatatcacgt ggacggacaa
    20581 gggtgtgact ctgggtgtgg ttgtcgcatc caagggctac ccgctaaatt attcaaaggg
    20641 tgttgagttg ccagtcaaaa ccgatggcga catcattacc tactatgcag gggctaagtt
    20701 tgcggaaaat agcagagcac tgctctcaaa cggcggacga gtttatatgc tcgttaccac
    20761 agcagatacc gtcaaagaag cccaagccag catctaccaa gaactatccc aacaaaaaat
    20821 agaaggactc ttctaccgaa cagatatcgg aagcaaggca attaagtaaa gatataagaa
    20881 taacgcgccg tagtcgccaa acacgataat ggtcgtcgtg gtgaaaagac cagaacagtg
    20941 aatgttctgg tcagggggaa acttggagac cgtaggctca aagtttagga atgaaaccga
    21001 aggtttgctt ccgcctccat cacctaagac cattatcaaa aagaaaaata aaaattcaca
    21061 aaatacgtta atgatcgtat ggtttgcgag cgttagcgag ctaatataga acaatcaccg
    21121 ccgttgtgaa agaacgattg gatgataatc caatcgttca gggaaattgg aagaccttgg
    21181 gtttccaatt taggcatgag acacctttgg tggctgctgc cgtccctcac aagctaaggt
    21241 gattgttgaa aaagaggaaa aaggagaaga aatgaaacca gtaatttcca tcatcatggg
    21301 ctcaaaatcc gactgggcaa ccatgcaaaa aacagcagaa gtcctagacc gcttcggtgt
    21361 agcctacgaa aagaaagttg tttccgcaca ccgcacacca gacctcatgt tcaaacatgc
    21421 agaagaagcc cgtagtcgtg gcatcaagat catcatcgca ggtgctggtg gcgcagcgca
    21481 tttgccaggc atggtagctg ccaaaacaac ccttccagtc attggtgtgc cagtcaagtc
    21541 tcgtgctctt agtggagtgg attcactcta ttctatcgtt cagatgccgg gtggggtgcc
    21601 tgttgcgacc atggctatcg gtgaagctgg agcgactaac gcagctctct ttgccctccg
    21661 tctcctctct gtagaagata agtccattgc ggatgcactt gccaactttg ctgaagaaca
    21721 aggaaaaatc gcagaggagt cgtcaaatga gctcatctaa aacaatcgga attatcggtg
    21781 gcggtcaact gggtcagatg atggccattt ctgctatcta catgggccac aaggttatcg
    21841 cgctggatcc tgcggcggat tgcccggcct ctcgcgtggc ggaaatcatt gtggcacctt
    21901 ataacgatgt ggacgccctc cgtcagttgg cagaccgttg cgatgtcctc acttatgagt
    21961 ttgaaaatgt cgacgctgac ggtttggatg ccgttatcaa ggatggacaa ctccctcaag
    22021 gaacagatct gctccgcatt tcgcaaaatc gtatttttga aaaggacttt ttgtcaaaca
    22081 aggctcaagt cactgtggca ccctacaagg tcgtgacttc tagcctagac ttggcagata
    22141 tcgacttgtc gaaaaactat gtcctcaaga ctgcgactgg tggctacgat ggtcatggac
    22201 aaaaggttat tcgttcagaa gcagacttgg aagcagccta tgcgctagca gactcagcag
    22261 actgcgtctt ggaagaattt gtcaactttg accttgagat ttctgtcatc gtgtcaggaa
    22321 atggcaagga ggtgacgttt ttcccagttc aggaaaatat ccaccgcaac aatatcctgt
    22381 ctaagaccat cgtaccagcc cgcatttctg aaagtctagc agacaaggct aaagctatgg
    22441 cagtgcgaat cgcagaacaa ctcaacttgt ctggaactct ctgtgtggaa atgtttgcga
    22501 ctgatgatga cgttattgtc aatgaaatcg ccccacgacc acataactct gggcactatt
    22561 ctattgaagc ctgtgatttc tctcagtttg acacccatat tctgggtgtt ctcggagcac
    22621 cattaccagt catcaaactc catgcgccag ccgttatgct taatgtcctc ggtcagcatg
    22681 tcgaggctgc tgagcaatat gtgacagaaa attcaagcgc ccacctccac atgtatggta
    22741 aaatagaagc gaagcacaac cgcaagatgg gacatgtgac cttgtttagt gatgtaccgg
    22801 atagtgtgga tgagcttggg gaagggattg atttttagga caagtctatg atacaaatta
    22861 tcgttaatac atttattgaa aaggataaga ctggagcagt tgttgaagtg ttgtatgcca
    22921 gtgctgacca agataaggta caagctaaat atgaagaact agctgcacaa taccccgaaa
    22981 attatttagc tatctatgat gtaccgctgg atacggattt gaatacacta gatcattacc
    23041 cgtctgtgtt tattgaaaaa gaggagtttg agtagaaatc ttggtttacc tagatagctt
    23101 attcccaaca gcttaagaag aaaggaaaaa ttaacacatg atcaaccgtt actctcgccc
    23161 tgagatggcg aatatttgga gtgaagaaaa taaataccgt gcttggcttg aggtggaaat
    23221 cctctctgac gaggcatggg ctgagttggg ggaaatccct aaggaagatg tggctttgat
    23281 tcgcaagaag gcggactttg acatcgaccg tattttggaa attgagcagg agacgcgcca
    23341 cgatgtggtg gctttcacgc gtgcggtttc tgagactctt ggtgaagagc gcaagtgggt
    23401 tcactatggg ttaacttcta ccgacgtggt ggatactgct tatggttacc tctacaagca
    23461 ggccaacgac atcatccgtc gtgaccttga aaacttcact aatatcatcg ctgacaaggc
    23521 caaggagcac aagttcacca tcatgatggg gcgtactcat ggtgtgcacg ctgagccgac
    23581 aacctttggt cttaaattgg caacttggta cagcgaaatg aaacgcaata tcgagcgttt
    23641 cgagcatgca gctgctggtg tagaagctgg taagatttct ggtgcggttg ggaactttgc
    23701 caatatccca ccatttgtag aggagtatgt ctgcgataaa cttggcatcc gtgcccaaga
    23761 aatctctaca caagtccttc ctcgtgacct tcacgctgag tactttgcgg ttcttgccag
    23821 cattgcgact tcaatcgaac gtatggcgac tgagattcgt ggtctacaaa aatctgagca
    23881 acgcgaagta gaagagttct ttgctaaagg gcaaaaaggg tcttcagcaa tgcctcacaa
    23941 acgcaaccca atcggttctg aaaatatgac tggtctggcg cgtgtcattc gtggtcacat
    24001 gattacggct tatgaaaacg tcgctctctg gcacgaacgc gatatttctc actcatcagc
    24061 tgagcgtatc atcacaccag atacgaccat tttgattgac tacatgctca accgttttgg
    24121 aaatatcgtc aagaacttga cagtcttccc agaaaatatg atccgaaaca tgaactcgac
    24181 ttttggtctt atctttagcc aacgggctat gttgacattg attgaaaaag gcatgacccg
    24241 tgagcaagcc tatgacttgg tgcaaccaaa aacagcctac tcttgggaca accaagtaga
    24301 ctttaaacca cttcttgagg cagattcaga agtaacatca cgtctcactc aagaagaaat
    24361 cgatgaaatc ttcaacccag tttattacac caaacgagtg gatgatatct ttgaacgtct
    24421 tggactaggt gattaattaa aaaataaaca gcgagcttca atctcgctgt ttatttttta
    24481 tcgaaaagac ttagtcttct tttcttttag tgagtccata ggctgctagt gtggccatga
    24541 gtcctgcgac tactagtcct gcagaatcgt gagttcctgt ttcaggaagt tttttctcta
    24601 ttaccacagg agctggatct tgaggaagag ctttgctttc ctcagcagga gcagttgatg
    24661 gagctggttg gcttgggatt tctagttttg gtttttcttc agcaatagcg gcttgtccgt
    24721 tttcatcgcc tacatgtgtt accatagttc cgacttcgac tatttgagta acggcttcct
    24781 gtgctacgac actatttaca agtgttttca cttccttacc atcggcagaa gtgctcacag
    24841 agtagaagtt gctacgatgt ccattgacgc ccttagtaat gacttgtgtt tttcctttga
    24901 gtaagagtgg attttcacga gtcactgtgg taaatggaat ttcttctttt tggatatcca
    24961 gtctaggttt tacctcagta gttggtgcaa gaccactttc atcacccttg tgagttacag
    25021 gagcgccaac ttcaaccact tggtttataa cttctttggt tacctggcta tcaaggactg
    25081 tttctgttgt ttttccattt tcagtgagta cagagatgta atgagttcgc tcacctttga
    25141 ctcctgctgt gataatattt tcctgaccag ctgggaggtt aggattttct ttcttgataa
    25201 cttcaaatgg aatttcttca gttcttgtga tgagttctgg tctggtttca acattggcag
    25261 ccacttcatt ttcatccagg cttcctgaat gagttgcagc tggtttgagg ccttgaagag
    25321 cggcttttag gttggctaca agtgtgtcaa gctcagcttg tttattacgg ttgaggttgt
    25381 aatttagagc tgttttagct gcgtcaaggg cctcaagact ttctttacta tatccttcta
    25441 agtttgtagg aattttagct aattcttcgc ggagagcatt ataattagca cggaagtagt
    25501 ctttgttgtg gtctgcaaag gcagtcatga gttcaaagat ttcctcttcc ttgtattcag
    25561 cgcttggtct atctgcccag attgaaagca tacttccgac tgttggaaga tctacttcag
    25621 gatatttggt agaagctagt tgattgaatg gtgtttttcc agtattctca atagctttct
    25681 tgaggaaacc accaccatct tctggttttt gaccaagaat gtagtaccag tcaccgttgg
    25741 tattcaagaa tttatagcct ttgcttgcta ggtattgagg tgatgcgagg ttatatcccc
    25801 accagccttt agaccagtaa gaaatcaaga catctttgtc aaactgaaca tcgtccttgt
    25861 cttcatagta gaagccatcg ttgaaggcca ttggttgaag ccctctttct ttggccatag
    25921 ctgcgagggt gttggcatat tcggcaaatt tgccatagag ttgataccac ttgaggtagt
    25981 accagccttg ggcactagtc gcatcgttgg cgtattcgtc agtaccaaag ttgaaaatct
    26041 ttgttttacc tgcaaagaag tccatgtatt taccgatgag ggcttttaca aagttcatcg
    26101 cttcttcgtt tttcaagtcc atagttgttt ttgaaacttt atcaaagtgg gcttgaggat
    26161 ttttaatacc taatttttcc atggcaacca gcatagcatc catgtgacct ggactgttaa
    26221 tagctgggat gagaccgatg tccttagatt tagcgtattc aattagctct gttacttctg
    26281 cctgtgttag tgcagtaccg tttggatcgt cgtagtaagc tttagttcct tcgataatag
    26341 cttttttaac gtcatcacta gcataggttt ttccgttggc agtaatggtc atatcatcga
    26401 gtagaaagcg aagtccgtca tttcctagaa ggagatggac atcagaatat ccgagctcac
    26461 tggccttgtc tacgatgcgt ttgagctggt tcagagtaaa gtatttgcgt ccagcatcga
    26521 ttgagattac cttgtttttg gcaagttttt caacctcacg tttagcttct tcttcttttt
    26581 gagcttcagg cgtgagggtc aagttgttga cagtttcttg aagtttagca atggcttgat
    26641 caatcgtatc ttgttgggca cggctaaggt tgctatcgag agagcgaata gctttttcag
    26701 cttcttttac ggccgcgacg ctttctgcag tataacggtt caggtctttt ggtacctcgt
    26761 taagtgtttg ctctgcagat tcataatcag ctgcgaagta ttcagcgttg gcatttgcaa
    26821 aatgacgcat gagtttgaag aggcgtgatg gtgaataacg tgcagatgga gtgtcagccc
    26881 aagcagctac catactaccg atgattggga tatcagctcc ttctgttttt ggtacagaag
    26941 tgattggtgt gtttttaata ccattgagcc cctgatcgag attgtaccag ccttggccat
    27001 cagcgtttcg tccaagaacg tagtaccaag catcattggt attaaggatt tggtgacctt
    27061 tttcagctag tagtttagaa gaagcgacat cgtagcctcc ccaaccacca gtccacatag
    27121 aaacgatgat gtctttgtca aaactaccaa agcttgtgtc gctattgtag tagataccgt
    27181 cgttaaaggc cattggtttg agaccgtgcg attttacaat acgagcgagg tcattggcgt
    27241 aggcaataaa tttttcatag ccttttacag ggtagccttc gtttggatag tatttatcag
    27301 cttgaagcac actccaacct ttagcatctg tcgcatcatt ggcatattca tcaagtccga
    27361 tgttgaagat ttcagtcttt ttcgcgaaat aagcagcata cttgtcgata agggcttttg
    27421 taaaagcgac agcttgttcg ttgtcaagat tgacagtacg ggctgattcc ttcccaaaat
    27481 agctaaagtt agggttttgg attcccaatt ctttcatggc attgagaatc gcatccatgt
    27541 gaccaggact atttactgtc ggaatgagac cgataccttt atctttggca tagttaatca
    27601 gatctgtcat ttgactttct gttaagtgat tgccgtttgg atcgttgtaa taatcatttg
    27661 tacctttttc aatggcgcgt ttgacatcgt cactggcata ggtcttgccg ttagctgtga
    27721 tgctcatatc gtccaacatg aaacggagtc catcatttcc gactaatagg tgtaaatcag
    27781 tgtagccata atgtttcgct ttatcgatga tttccttgag ctgttctggt gagaaatatt
    27841 tacgtccagc atcaatagaa acaattttct ttttcgctag tttttcattt acagttgcag
    27901 cacgttcctt tcctgcctct gtttccggtt tgtcatcctc tgctttcgct tcatcttttt
    27961 tagctggttt atccttgtca gtcttgtctg tatttgactc tttagaatca acctctttcg
    28021 cttcttcctt tttagggcta gcttcttctg cctttttatt agcagtttct ttttcagcag
    28081 aagttggagt taccacttct gctttatcac taggagttga actaacttcc tcttgtggtt
    28141 tttcttctgt ttttggaaga ctagctacct tatcagtagc tggagtttct gtttctacag
    28201 tttttggagc ttctggttga agctctgctt taggtgtttc ctcagtccga ttttcggatg
    28261 attgagggga atcagaaacc gtatggatgg tcggttggtt ttctgtagta gtaggagtaa
    28321 ctccatcggc tgcaacagtc tgtgcttgga aggcaaatcc aattagaaca gaagctgctc
    28381 ctacagcgta tttacgaata gaaaaacgct gttgtttttc atgtttcatt gcaaaacctc
    28441 ctgattgcat tgttatattg atagcgatta tataaatcaa cgcctttatt ttatttctta
    28501 tattaacgag agtcaagagg agatgacaaa aaactataat aagtataaaa aaatataaaa
    28561 tttaaactta agatttcaga ttggtcggaa aaaatacgta tatatatcta gtataatttt
    28621 tggttctatt tctataaaat attccacaaa ttatagaatt ttccaaaaat aggtaagcgc
    28681 tacctttttg gtgtggtata ataagcatag aaaaagccca agcgattagc tcaggctttc
    28741 ttcttagtga tcacggtcac atgagataaa tttaatcttg tagtaatcag atcgtttgta
    28801 agtttcactg tattctaaaa cttggccagt tgattcgagt ttggtgattt tagtttgtag
    28861 gacagtaggg aattgttcat cgactccgag gactgaagcc gcatgttctg gagttggaaa
    28921 gactatttcg ttgatttctt caaagtgttc atcattcatg tgaatgtggt agtctaactt
    28981 gaaacgatta tagatagaac tatagtattc aaggtttgga taatttgcgt tgatatattg
    29041 ttctgggatg taggatgtat ggtagatata aacgacaccg tttgattcgc ggatacgttc
    29101 aatcttgtag tagaattgat cgccgcgtag acccaatttt tccaagtaaa caagcttgtt
    29161 tccgcgttca attgaaagaa cagttacctt atcatcttta gcattgaaga gttcaatatc
    29221 tgaaaactct acaagcttgt gtttgcgtgc acgtgaaacg aaggttcctt ttccttgttg
    29281 gcggacaata tagccatctt tggcaaggtc gtttaaggcg cgaacaactg tgatagagct
    29341 gacatcgtac attgaaatga gttctgcttc agtgtaaaat ttatctccac tgctaaactg
    29401 cccagagatg attttatttt ttaattcgtc ttttatgtat tgatatttgg gaattgccat
    29461 atttttacct ctattttcct tctccatagg aaattttacc ataaaagcga aaaaaatagt
    29521 agtcttttga ataaaaaatt agaataatag tttgaaaaat taagcgatat agggattgct
    29581 catattttat caatgtattc tatacaaaat tattttaggt cccatattcc gaatttaaag
    29641 agcgtttgaa atgggtctaa aaatgtttga aactaattga atgtgtgtat aatagtaaaa
    29701 atgcagtaaa tatcccgaca atttctattg acaattcaaa cagattggtt tataattaat
    29761 ataacaacaa atgaaagcgc aaactttcgc ggtcggaagg tagttttatg acacgatttg
    29821 agatacgaga tgatttctat ctcgatggaa aatcatttaa gattttatct ggtgccattc
    29881 attattttag ggttcctcca gaggattggt atcattcgct ctataacttg aaggctcttg
    29941 gttttaatac ggtagagact tatgttgctt ggaatttaca cgagcctcgt gaaggtgagt
    30001 ttcattttga aggtgatctg gatttagaga aatttctcca aatagcgcag gatttgggtc
    30061 tctacgcaat tgtgcgtccg tctccattta tctgtgcgga atgggaattc ggtggcttac
    30121 cagcttggct cttgaccaag aacatgcgaa ttcgctcatc cgacccagta tatatcgagg
    30181 cagttggtcg ctactatgat cagttattgc caagactggt gcctcgtttg ttggacaatg
    30241 gtggcaatat tctcatgatg caggttgaaa atgagtatgg ttcttacgga gaagataagg
    30301 cttacctgag agcgattcga cagctaatgg aagagtgtgg cgtaacctgt cccctcttta
    30361 catcagatgg tccatggcga gctactctga aagctggaac cttaattgaa gaggacctct
    30421 ttgtaacagg aaactttggt tctaaggcac cttacaactt ttcgcagatg caggaattct
    30481 ttgatgaaca tggtaagaaa tggccactca tgtgtatgga gttctgggat ggttggttca
    30541 atcgctggaa agaaccgatt atcacacggg atcctaagga attggcagat gcagttcgag
    30601 aggttttgga acaaggctct atcaatcttt acatgttcca cggtggtaca aactttggtt
    30661 tcatgaatgg ttgctcagct cgaggaactt tggacctgcc acaagttacg tcttatgatt
    30721 acgatgccct tctggatgaa gaaggaaatc caactgctaa atatcttgca gtcaagaaga
    30781 tgatggcaac acatttttca gagtatccgc agttggaacc actctacaaa gagagtatgg
    30841 agttggatgc tattccacta gttgaaaaag tttctttgtt tgaaacctta gatagcttgt
    30901 caagtcctgt agaaagtctc tatcctcaaa agatggagga gctgggacaa agttatggct
    30961 acctacttta tcgaacagaa acaaactggg atgcagaaga agaaagactt cgtatcattg
    31021 atggtcgaga tagggcccag ctgtatgtcg atggtcagtg ggttaaaact caatatcaga
    31081 cagagattgg ggaagatatt ttttatcaag gtaaaaagaa agggctatct aggttagata
    31141 tcttgataga aaatatgggg cgtgtcaact atgggcataa gttcttagcg gatacgcaac
    31201 gtaagggaat tcggacaggg gtctgtaagg atctgcattt cttactaaac tggaaacact
    31261 atccactccc actagacaat cctgagaaaa ttgatttttc aaaaggatgg actcaaggac
    31321 aaccagcctt ttacgcttat gactttacag tcgaagagcc aaaagatact tacctagact
    31381 tgtctgagtt tggtaagggg gttgcctttg tcaatgggca gaatctagga cgtttttgga
    31441 acgttggccc aactctctca ctttatatcc ctcatagcta tctcaaggaa ggtgccaacc
    31501 gcatcattat ctttgaaaca gaaggtcaat ataaagaaga gattcattta actcgtaaac
    31561 ctacactaaa acatataaag ggggaaaact tatgacaatt gtaggatgcc gtattgatgg
    31621 acgtttgatc cacggacaag tagccaatct ttgggctgga aaactaaatg tttcacgcat
    31681 tatggttgta gacgacgaag ttgtcaacaa cgatattgaa aagagtggtt tgaaacttgc
    31741 gacaccacca ggtgtgaaat tgagtatttt gccagttgag aaagctgcag ccaatattct
    31801 tgctggtaaa tacgatagcc aacgtctctt tatcgtggct cgtaaaccag accgcttcct
    31861 tggtttggta gaagcaggtg taccacttga aacccttaat gttgggaata tgtctcaaac
    31921 accagaaaca cgttctatta cacgttctat caacgtagta gacaaggatg tggaagactt
    31981 ccacaaactg gcagaaaaag gtgttaaact tactgctcag atggttccaa atgatccaat
    32041 ttcagacttt ttgagcttat taaaatagga aaaaaatttt taggaggtca ttgttatgat
    32101 acaatggtgg caaattttac ttctcacttt gtactcagct tatcaaatct gtgatgagtt
    32161 gacgatcgtt tcatctgcag gttctcctgt atttgctggt ttcattactg gtttaatcat
    32221 gggagatgtg actactggtt tacttatcgg tggtaacttg caactgttcg ttcttggggt
    32281 tggtaccttc ggtggtgctt ctcgtatcga cgcaacttct ggtgcggttc ttgcgacagc
    32341 cttctctgtt tcacaaggaa ttgatgcacc gcttgccatt actacaatcg ctgtaccagt
    32401 agcagctctc ttgacttact tcgacgttct tggtcgtatg actactacct tcttcgctca
    32461 ccgtgtggat gctgcaatcg aacgctttga ctataaaggt attgaacgca actacttgct
    32521 tggtgcgatt ccgtgggctc tatctcgtgc ccttccagtc ttctttgccc ttgcttttgg
    32581 tggtgccttt gtacaatcag tagtagactt cgttgaagcc tacaaatggg ttgcagatgg
    32641 cttgacactc gcaggacgta tgcttccagg tcttggattt gcaatcttgc ttcgttacct
    32701 tccagttaaa cgtaaccttc actaccttgc tatgggattt ggtttgacag ctatgttgac
    32761 tgttctttac tcatatgtaa caggtcttgg tggcgctgtt gctggtatcg taggtactct
    32821 tcctgctgaa gttgctgaaa aaattggttt cgtgaacaac ttcaaaggtt tgtctatgat
    32881 tggtatttct atcgtaggta ttttccttgc agtgcttcac ttcaaaaata gccaaaaagt
    32941 agctgtagca gcaccttcta caccatcaga aagtggggaa atcgaagatg acgaattcta
    33001 attacaaact tacaaaagaa gattttaatc aaatcaacaa acgtagcttg tttactttcc
    33061 aattaggttg gaactacgaa cgtatgcaag cttctggtta cctttacatg atcttgcctc
    33121 agttgcgtaa aatgtatggt gatggaactc ctgaattgaa agaaatgatg aaagttcata
    33181 ctcaattctt caatacttca ccattcttcc ataccattat cgctggtttt gaccttgcca
    33241 tggaagaaaa agatggtgta ggttcaaaag acgctgttaa cggtatcaag acaggtttga
    33301 tgggaccatt cgctcctctt ggggatacaa tctttggttc acttgtacct gctatcatgg
    33361 ggtcagtcgc agcaactatg gctatcgctg gccaaccttg ggggatcttc ctttggattg
    33421 cagttgcagt agcgtatgac atcttccgtt ggaaacagtt ggaatttgct tacaaagaag
    33481 gggttaacct tatcaacaac atgcaaagta ccttgacagc tttgattgac gctgcatctg
    33541 tacttggtgt cttcatgatg ggtgctcttg tagcaacagt gattaacttt gaaatttctt
    33601 acaagttgcc aatcggtgaa aagatgattg atttccaaga catcttgaac caaatcttcc
    33661 cacgtttgct tccagcaatc tttactgcct ttatcttctg gttgcttggt aaaaaaggta
    33721 tgaactctac taaagctatc ggtattatta tcgtacttgc tttggctctt tctgcccttg
    33781 gtcactttgc acttggaatg taattcctta tgactaaatc attaattttg gtgagccatg
    33841 gtcgcttctg tgaggagctt agaggtagca cagaaatgat tatgggccca caagacaaca
    33901 tttacacagt agctcttctt ccagaagatg gcccagaaga atttactgct aaatttgaag
    33961 ctgttattga aggattggat gatttcctag tctttgcgga tcttctcggt gggacacctt
    34021 gtaatgtggt gagtcgcttg atcatggaag gtcgtgatat tgacctttac gcagggatga
    34081 atcttccaat ggtgattgaa tttatcaatg cgagccttac aggcgcagat gcggactaca
    34141 agagccgtgc tgcagaaagc attgtgaaag ttaatgacct gttagcgggc ttcgatgatg
    34201 acgaagatga ataatactct tcgaaaatct cttcaaacta cgtcaacgtc gccttgccgt
    34261 aggtatatgt tactgacttc gtcagtctta tccggcaacc tcaaaacggt gttttgagct
    34321 gacttcgtca gtcttatccg gcaacctcaa agcagtgctt tgagcagcct gcggctagtt
    34381 tcctacagat tttagttgga actcgattca attcatgtga caacgtgaaa atcgttagag
    34441 cattttatat agaatataca tgggaatgga gcttactccc attcccatat ttaatagaaa
    34501 aagaggaact caatgctaca ttatacaaaa gaagacttgc tcgaattggg tgcagaaatc
    34561 actacgcgtg aaatctacca acagcctgat gtatggagag aagcttttga attttatcaa
    34621 gcaaaacgtg aagaaattgc agcctttcta caagaaatcg ctgataaaca tgactatatt
    34681 aaggttatct tgacaggtgc tgggacttct gcttatgtgg gagatacctt gctaccttac
    34741 tttaaggaag tctatgacga acgcaaatgg aatttcaatg ctattgcgac aacagatatc
    34801 gttgccaaac cagcaaccta tttgaaaaaa gatgtggcaa ctgtccttgt gtcttttgct
    34861 cgtagtggga actcgcctga aagtgtggcg actgttgatt tggccaaatc cttggtggat
    34921 gagctttatc aagtgacgat tacttgtgca gcagatggta aattggctct tcaagctcac
    34981 ggtgatgacc gtaatctctt gctcttgcaa ccagctgtct ctaatgatgc tggatttgcc
    35041 atgacttcta gctttacgtc tatgatgttg acaactctct tggtctttga tcctacagaa
    35101 tttgctgtta agtctgaacg ttttgaagtt gtatctagtc ttgcccgtaa agttttagac
    35161 aaggcagaag atgtcaaaga gctcgttgat ttagacttta accgtgtcat ctatctaggc
    35221 gctggtcctt tctttggact tgctcatgaa gctcagctca agattttgga attaactgct
    35281 ggtcaagttg cgaccatgta tgaaagccca gttggcttcc gtcacggtcc aaaatctctt
    35341 atcaacgaca atacagttgt tttggtcttt ggtacaacga cggactacac tcgtaagtac
    35401 gacttggact tggttcgtga agttgctggt gaccagattg ctcgtcgtgt tgtgcttttg
    35461 agtgatcaag cttttggtct tgaaaatgtc aaagaagtgg tccttggttg tggcggtgtc
    35521 ttgaatgata tttaccgtgt cttcccttac atcgtttatg cccaactctt tgccctattg
    35581 acttcactca aggtagaaaa taaaccagat acaccgtctc ctacaggtac agtaaaccgt
    35641 gtagtacaag gtgtcataat tcacgaatat caaaagtaag acagtgttta tgaattcttg
    35701 acaagaggat ttgtaaatta tcagataaac catagattgt cagtacgctt tctatggttt
    35761 gtttgcttga gagaaatagt aaaaggagaa cagaatgaaa gcatacacag agcgtgtatt
    35821 tggaaatgtt gagggtgagg atgtcttggc ctatcgattt gagacagacg gtggctacca
    35881 acttgaggtt atgacttatg gtgcgactat cttgcgctat gtcgcacctg acaaggctgg
    35941 aaattttgcc aatgttatct tgggatttga tgactttgat agttatgtag gcaatagtcc
    36001 caagcatgga gcaagtgtag gtcctgtagc gggtcgtatt gcaggtgcga cctttgagct
    36061 caatggtaag acctatgacc ttgaggttaa taatgctagc aactgtaatc acagtggttc
    36121 aactggttgg gattccagct tgtttgaagt tgaagaagta agcgatcatg gcttgactct
    36181 ctacacagag cgtacagatg ggacaggagg gttccctgga aatctcaaga tttggatcag
    36241 ttatcacttg gaagaaactg gtgcctatga aatcagctac aaggtaacga ccgatcagga
    36301 tacgctggtc aatccaacca accacagcta tttcaacttg tctggtgatt tcacgcagac
    36361 gattgaccgt catgtcttcc aactaaacac agagggcatt tactcaatcg ctcctgacgg
    36421 tgttcctgcc aaaactccag aagccaaccg tgatgtggtc aaacacatct acaatggtgc
    36481 cttgttgaag gatatctttg cagaagaaga tgagcaaatc cagctggcat caggtttgga
    36541 tcatccattt gcccttcctg caggccatga caatgctgga ttcctttatg accaaaattc
    36601 aggtcgcttc ctgcttttca agacagaagc tccttgcttt gtggtctaca cagcaaactt
    36661 tgtggatgaa agtgtcatca taggaggtca gccaatgcta cagcacaatg ggattgctct
    36721 tgaagcgcaa gctttaccag atgccattca cagtgacctt aaaggccaag tcattcttaa
    36781 agctggtcaa accttcacca gtaagacacg ttatgaactt gttgtgaaat aaaaaaagct
    36841 ggtcaaaaag tctttaaaat taaaataacg catattgtca ggtgatgaaa agtttgataa
    36901 tatgcgtttt attatgaaat gatttacttt atattatcct gaaatggtgt tatttttgag
    36961 ttatctggct tgactttctt gatggaaatt atataatagt tgtaacaatg ataattacaa
    37021 ctagaaaaga ggaccattta tgacctatga atacaagagt cacatttatt tggcagagac
    37081 agctttaaat gtaaaggatt tggccagtca aacagccttt tatcagcaag ttattggttt
    37141 agaaatctta tctcaaactg agacagagtc cattctaggc cttggtggaa aagtcttggt
    37201 acagctgatt caagcacaag agagcggaga agtgagggaa tattatggtc tttaccattt
    37261 ggccattctc ttgcccacac gcaaggcttt agctgatgtc ttgaaacacc tgacagattt
    37321 acaaattcct cttgtcggcg gtgcagacca tggttacagt gaagctattt acttggaaga
    37381 tttggaggga aatggcattg aactctatcg agataagcca gtttccacat gggatattcg
    37441 agaagatgga cgcattatcg gagtgacaga ggctcttgcg gcgcaggaca tttatgagtt
    37501 gggggaaaga gtagagccct ttatcctggc agaaggtacg agaatggggc atattcatct
    37561 ttccgtcaag gatagtcgaa agtccagcca gttttatcaa aaggtgttag ggctagagga
    37621 taaattcagt gtgcctagcg ctagttggat tgcggctgga gattaccatc atcatttagc
    37681 agttaacgaa tggggaggaa aaggtctggc ttcgcgtaag caaggcttac caggtttagc
    37741 ctactatgtc atcgaagtcg cacacaaaaa agaactatta acgattgccc aacgagcaca
    37801 agaagttgac gcaccaatca aatggatgac atcgagccaa ttggaaatca cagactcaga
    37861 tggcatcgtg acccgtattc gtttagcaag gtaaaattag gaatttttaa taagttataa
    37921 gtattgctag tttgcttttt gaacggtctt tggtaacaga actgcgtgag ctggatgggc
    37981 gagaattttg acaaagaagc tgattagaga tataatgaag aaaaatcgag caaggaaaaa
    38041 gaaatgacaa attcaaagta tattacttgt ttgaaacgtt cagagggcca gttgtgtggg
    38101 attcaaaaga tgattgaagg agatcgtgac tgtgctgata ttgtgacgca actgacagca
    38161 gtgagatcta gtgtagagcg cgtgattgag atgataatta ccgaaaatct tactgaatgt
    38221 atcaatcagc cactagatga ttctgaagct caaaaggaac gcttagaaaa ggctatccga
    38281 tacttgatta aacggaaata aatgaatgtt ttgagacgat atgtgcaaag gtctattaac
    38341 tattagaata gtttaatggg agtcaaaaga agttgtaaaa aatctttaaa attaaaaaaa
    38401 cgcatagtat caggtattga aatgtactga ccccaaaaag ttagattttt tctgtctaac
    38461 ttttggggtg cagttcataa gaaccttggt aatatgcgtt ttattatggg gagatttata
    38521 cttttcgaaa atctcttcaa accaggtcag cttcaccttg ccgtagatat ggttactgac
    38581 ttcgtcagtt ctatccacaa cctcaaaaca gtgttttgag ctgacttcgt cagttccatc
    38641 cacaacctta aaacagtgtt ttgagctgac ttcgtcagtt ccatccacaa ccttaaaaca
    38701 gtgttttgag cagcctgcgg ctaacttcct agtttgcact ttaattttca ttgagtatta
    38761 cttcatcttc tcatgaaatt gagtttttgc ccagttcctc ttgattattc tacttgacca
    38821 ggccaagcat tcataccacc ttctacgttg gtaacggtga ggccttggga gatgagaaat
    38881 tggcaggtag atgcagagcg gactcctcct tgacaaataa catagtattc atggtcaggt
    38941 ttgagttctt tgtagccttg ctctaaggta cttaatggaa gatttttggc acctggtgca
    39001 tgtcctgctt ggaattcatg tgcttcacgg acatcgataa gttctagatt ttcattttgg
    39061 tattttccat aaaagtcagc catgctgata ctagtttcca tattctactc cttctgggtt
    39121 aaccattttg tatagtgaat aagcgccgtc aaggttttgg gcggtaaatc ctgcttgctt
    39181 gaggataggc tctgcgatat agctgcgcaa accactgtgg cagctgacga tgtaggcttg
    39241 ttttttgtcc agttcatcag cttcctcctt gacactttgt cagtttttga tacaatagta
    39301 caaaattaga ggaggtgggc tatgattcag aaacatgcga ttcctatttt agagtttgat
    39361 gacaatcctc aggcggttat catgcccaat cacgaggggc tggacttgca gttgccaaag
    39421 aagtgtgttt atgcattttt agatgaggag attgaccgct atgcaaggga agtaggggcg
    39481 gattgtgtcg gcgaattcgt ttctgctacc aagacctatc cagtctatgt catcaactac
    39541 aagggtgagg aggtctgtct ggctcaggct cctgttggct ccgctccagc agcccagttt
    39601 atggattggt tgattggcta tggtgtggag cagattatct ctactgggac ctgtggtgtt
    39661 ctagctgata tagaggaaaa tgcctttcta gtccctgttc gcgctctgcg agatgaagga
    39721 gccagttacc actatgtggc accttctcgt tatatggaaa tgcagccaga ggctattgct
    39781 gctattgagg aagttttgga agacagaggg attccttatg aagaagtcat gacctggacg
    39841 acagacggtt tttaccgaga aacggctgaa aaggtggctt atcgtaagga agaaggctgt
    39901 gctgttgtgg agatggagtg ttctgctctt gcggcagtag ctcaattgcg tggggttctc
    39961 tggggtgaat tgttgttcac agcagattct ctagcggact tggaccagta cgacagtcgt
    40021 gactggggct cggaagcttt taataaggcg ctagaactga gtttagcaag tgttcaccac
    40081 ctttagttgt actggcaaag gatttgtttt atcataaaat gtctagctca tacttttcaa
    40141 aaatatgttt aaacgaggtc accttcctct tgtcctaagc atgttgaggt tgggaaaaat
    40201 ctttaaaatc agaaaaacgt atcatatcag gtgatgaaaa ccttgatact atgcgtttta
    40261 tgttggtaag atttagagtg agatgaaatg atactcttcg aaaatctttt caaaccaggt
    40321 cagcttcacc ttgccgtagg tatatgttac tgacttcgtc agtcttatcc ggcaacctca
    40381 aaacggtgtt ttgagctgac ttcgtcagtt ctatttgcaa cctcaaaaca gtgttttgag
    40441 caatctgtga ctagctttct aatcgatgcc ttggttctca ttgcctataa tcaaaaagag
    40501 aaattttctc ctgaaaagca tatagagtag ctggcgttaa aagctcctgt cttgcttttt
    40561 tgacctatag tcacatctat caagtattgt tcttgcctaa gctatcaata aaaaggtggc
    40621 attttttagg cttggtgtta gtagattttg ccttatccta tctaagtcat ttcgaacttt
    40681 ttatggtaca atggaaacat gttattcaaa ttatctaagg aaaaaataga gctaggctta
    40741 tctcgtttat cgccagcccg tcgtattttt ttgagttttg ccttggtcat tttactaggc
    40801 tctcttcttt tgagcttgcc ctttgtccaa gttgaaagct cacgagcgac ttattttgat
    40861 catcttttca ctgctgtctc tgcagtctgt gtgacaggtc tctcaaccct tccagtagct
    40921 cacacctata atatatgggg ccaaataatc tgtttgctct tgattcagat cggtggtcta
    40981 gggctcatga cctttattgg ggttttctat atccagagca agcaaaagct tagtcttcgt
    41041 agccgtgcaa ctattcagga tagttttagt tatggagaaa ctcgatcttt gagaaagttt
    41101 gtctattcta tttttctcac gacctttttg gttgagagct tgggagctat tttgcttagt
    41161 tttcgcctta ttcctcaact tggctgggga cgtggtcttt ttagttccat ttttctagcg
    41221 atctcagcct tctgtaatgc cggttttgat aatttaggga gcaccagttt atttgctttt
    41281 cagaccgatt tactggtcaa tctggtgatt gcaggcttga ttattacagg cggccttggt
    41341 tttatggtct ggtttgattt ggctggtcat gtaggaagaa agaaaaaagg acgtctgcac
    41401 tttcatacga agcttgtact attgttgact ataggtttgt tgttatttgg aacggcaact
    41461 actctctttc ttgagtggaa caatgctgga acgattggca atctccctgt tgccgataag
    41521 gttttagtta gcttttttca aacagtgacg atgcgaacag ctggcttttc tacgatagat
    41581 tatactcagg ctcatcctgt gactcttttg atttatatct tacagatgtt tctaggtggg
    41641 gcacctggag gaacagctgg gggactcaag attacgacat tttttgtcct cttggtcttt
    41701 gcacgaagtg agcttctagg cttgcctcat gccaatgttg cgagacgaac gattgcgccg
    41761 cgaacggttc aaaaatcctt tagtgtcttt attatctttt tgatgagctt cttgatagga
    41821 ttgattctgc tagggataac agccaaaggc aatcctccct ttatccacct catatttgaa
    41881 accatttcag ctcttagtac agttggtgta acggcaaatc tgactcctga ccttgggaaa
    41941 ttggctctca gtgttatcat gccacttatg tttatgggac gaattggtcc cttgaccttg
    42001 tttgttagct tggcagatta ccatccagaa aagaaagata tgattcacta tatgaaagca
    42061 gatattagta ttggttaaga aaggaaagag catgtcagat cgtacgattg gaattttggg
    42121 cttgggaatt tttgggagca gtgtcctagc tgccctagcc aagcaggata tgaatattat
    42181 cgctattgat gaccacgcag agcgcatcaa tcagtttgag ccagttttgg cgcgtggagt
    42241 gattggtgac atcacagatg aagaattatt gagatcagca gggattgata cctgcgatac
    42301 cgttgtagtc gcgacaggtg aaaatctgga gtcgagtgtg cttgcggtta tgcactgtaa
    42361 gagtttgggg gtaccgactg ttattgctaa ggtcaaaagt cagaccgcta agaaagtgct
    42421 agaaaagatt ggagctgact cggttatctc gccagagtat gaaatggggc agtctctagc
    42481 acagaccatt cttttccata atagtgttga tgtctttcag ttggataaaa atgtgtctat
    42541 cgtggagatg aaaattcctc agtcttgggc aggtcaaagt ctgagtaaat tagacctccg
    42601 tggcaaatac aatctgaata ttttgggttt ccgagagcag gaaaattccc cattggatgt
    42661 tgaatttgga ccagatgacc tcttgaaagc agatacctat attttggcag tcatcaacaa
    42721 ccagtatttg gataccctag tagcattgaa ttcgtaaaga gggatgaccc ctcttttttg
    42781 atgcccaaga tggcaaatag agacagaagc cccttgtctt ctagtaaaag ttcttcaaag
    42841 gctggacttt atggtaaaat agaaggaagt gacaagagag agtaatactc aatgaaaatc
    42901 aaagatcaaa ctaggaaact agctgcgggc tgctcaaaac actgttttga ggttgtggat
    42961 agaactgacg aagtcagctc aaaacactgt tttgaggttg cagatagaac tgacgaagtc
    43021 agtaacatct atacggcaag gcgacgttga cgcggtttga agagattttc gaagagtata
    43081 agaaaaaatc agtcccctaa aggagcagat tatgaagtta ttgtctatcg ccatttctag
    43141 ctataatgca gcagcctatc ttcattactg tgtggagtcg ctagtgattg gtggtgagca
    43201 agttgggatt ttgattatca atgacgggtc tcaggatcag actcaggaaa tcgctgagtg
    43261 tttagctagc aagtatccta atatcgttag agccatctat caggaaaata aatgccatgg
    43321 cggtgcggtc aatcgtggct tggcagaggc ttctgggcgc tattttaaag tagttgacag
    43381 tgatgactgg gtggatcctc gtgcctactt gaaaattctt gaaaccttgc aggaacttga
    43441 gagcaagggt caagaggtgg atgcctttgt gaccaatttt gtctatgaaa aggaaggtca
    43501 gtctcgtaag aagagtatga gttacgagtc agtcttgcct gttcggcaga tttttgacta
    43561 ggaccaggtc ggaaatttct ccaaaggcca gtatatcatg atacactcgc tgatttatcg
    43621 gacagatttg ttgcgtgcta gccagttcta actgcctgaa catacttttt atgtcgatga
    43681 tctctttgtc tttacgcccc ttcagcaggt caagaccatg tactatctgc ctgtcgattt
    43741 ctatcgttat ttgattgggc gtgaggacca gtctgtcaat gagcaagtga tgattaagcg
    43801 cattgaccag caactcaagg tcaatcgact cttggtagac cagcttgatt tgtcccaagt
    43861 gagtcatcct aaaatgcgag aatatctgct gaatcatatt gaaatcacga cggtgatttc
    43921 cagtaccctg ctcaaccgat ctgaaacagc ggagcatctg gcaaaaaaac gccaattgtg
    43981 gacctatatt cagcagaaaa atccagaagt ctttcaggct attcgtaaga ccatgttgag
    44041 ccgtttgacc aaacattctg tcttgccaga tcgcaaactg tccaatgtcg tctatcaaat
    44101 caccaaatct gtttatggat ttaattaata taagtgtttt ataagaggga tttaagaaaa
    44161 attttaactt tttcttagtc ctttttaatt tcaggagatt atactagagt catcaaataa
    44221 agaaagactc taaggagaat cctatgaaat tcaatccaaa tcaaagatat actcgttggt
    44281 ctattcgccg tctcagtgtc ggtgttgcct cagttgttgt ggctagtggc ttctttgtcc
    44341 tagttggtca gccaagttct gtacgtgccg atgtggtcaa tccgacccca ggtcaagtct
    44401 tacctgaaga gacatcggga acgaaagagg gtgacttatc agaaaaacca ggagacaccg
    44461 ttctcactca agcgaaacct gagggcgtta ctggaaatac gaattcactt ccgacaccta
    44521 cagaaagaac tgaagtgagc gaggaaacaa actcttctag tctggataca ctttttgaaa
    44581 aagatgaaga agctcaaaaa aatccagagc taacagatgt cttaaaagaa actgtagata
    44641 cagctgatgt ggatgggaca caagcaagtc cagcagaaac tactcctgaa caagtaaaag
    44701 gtggagtgaa agaaaataca aaagacagca tcgatgttcc tgctgcttat cttgaaaaag
    44761 ctgaagggaa aggtcctttc actgccggtg taaaccaagt aattccttat gaactattcg
    44821 ctggtgatgg tatgttaact cgtctattac taaaagcttc ggataatgct ccttggtctg
    44881 acaatggtac tgctaaaaat cctgctttac ctcctcttga aggattaaca aaagggaaat
    44941 acttctatga agtagactta aatggcaata ctgttggtaa acaaggtcaa gctttaattg
    45001 atcaacttcg cgctaatggt actcaaactt ataaagctac tgttaaagtt tacggaaata
    45061 aagacggtaa agctgacttg actaatctag ttgctactaa aaatgtagac atcaacatca
    45121 atggattagt tgctaaagaa actgtcgaaa aagctgtta
//
LOCUS       DAVBBO010000010        44969 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ST1
            SAMEA2066453-rid20184263.denovo.010, whole genome shotgun sequence.
ACCESSION   DAVBBO010000010 DAVBBO010000000
VERSION     DAVBBO010000010.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2066453
            Sequence Read Archive: ERR351777
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 44969)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 44969)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980402.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980402.1
            Genome Coverage       :: 176x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:17:33
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,141
            CDSs (total)                      :: 2,104
            Genes (coding)                    :: 1,953
            CDSs (with protein)               :: 1,953
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 16S)
            partial rRNAs                     :: 1 (23S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 151
            CDSs (without protein)            :: 151
            Pseudo Genes (ambiguous residues) :: 0 of 151
            Pseudo Genes (frameshifted)       :: 73 of 151
            Pseudo Genes (incomplete)         :: 76 of 151
            Pseudo Genes (internal stop)      :: 40 of 151
            Pseudo Genes (multiple problems)  :: 32 of 151
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..44969
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2066453-rid20184263.denovo.010"
                     /strain="ST1"
                     /db_xref="taxon:1313"
     gene            215..1978
                     /gene="aspS"
                     /locus_tag="VQU30_000543"
     CDS             215..1978
                     /gene="aspS"
                     /locus_tag="VQU30_000543"
                     /EC_number="6.1.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000830881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate--tRNA ligase"
                     /protein_id="HET2446710.1"
                     /translation="MKRSMYAGRVREEHIGQEITLKGWVGRRRDLGGLIFIDLRDREG
                     IMQLVINPEKVSAEVMATAESLRSEFVIEVTGQVAAREQANDKLPTGAVELNVTALIV
                     LNTAKTTPFEIKDGIEANDDTRLRYRYLDLRRPEMLENLKLRAKVTHSIRNYLDELEF
                     IDVETPFLSKSTPEGARDYLVPSRVNKGHFYALPQSPQITKQLLMNAGFDRYYQIVKC
                     FRDEDLRGDRQPEFTQVDLETSFLTEKEIQDITEGLIARVMKETKGIEVTLPFPRMKY
                     DDAMALYGSDKPDTRFDMLLQDLTEVVKGVDFKVFSEAPAVKAIVVKGAADNYSRKDI
                     DKMTEVAKQYGAKGLAWVKVVDGELNGPVAKFLTGIQEELTTALALEDKDLVLFVADT
                     LEVVNATLGTLRGRIAKELGLIDNDKFNFLWVVDWPMFEWSEEEGRYMSAHHPFTLPQ
                     EETAHELEGDLAKVRAIAYDIVLNGYELGGGSLRINQKDLQERMFKALGFSTEEANDQ
                     FGFLLEAMDYGFPPHGGLAIGLDRFVMLLAGEENIREVIAFPKNNKATDPMTQAPSTV
                     ALKQLEELSLQVEEDETNKTN"
     gene            1956..2897
                     /locus_tag="VQU30_000544"
     CDS             1956..2897
                     /locus_tag="VQU30_000544"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000806289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HET2446711.1"
                     /translation="MKQTKRIKRWRYYLRRFAYQIKILRVLQSISREKYDEKISASLV
                     YGFLSAVAVNFFFQPGHVYSSGATGLAQIISALSNHWFGFHIPISLSFYAINFPLMVL
                     AWYQIGHKFTVFTFITVSMSSFFIQFVPVATLTEDPIINSLFGGVVMGLGIGFALRNN
                     ISSGGTDIVSLTIRKKTGKNVGSISFLVNGTIMLIAGLTFGWKYALYSMITIFVSSRV
                     TDAVFTKQKRMQAMIVTNHPEKVIEKIHKKLHRGATMIHDAEGTYNHERKAVLITVIT
                     RAEFNEFKQIMTQVDPSSFVSVSENVHILGRFVEIDN"
     gene            complement(3017..3097)
                     /locus_tag="VQU30_000545"
                     /pseudo
     CDS             complement(3017..3097)
                     /locus_tag="VQU30_000545"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820552.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopuranose mutase"
     gene            complement(3233..4219)
                     /locus_tag="VQU30_000546"
     CDS             complement(3233..4219)
                     /locus_tag="VQU30_000546"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001145427.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HET2446712.1"
                     /translation="MPVTIKDVAKAAGVSPSTVTRVIQNKSTISDETKKRVRKAMKEL
                     NYHPNLNARSLVSSYTQVIGLVLPDDSDAFYQNPFFPSVLRGISQVASENHYAIQIAT
                     GKDEKERLNAISQMVYGKRVDGLIFLYAQEEDPLVKLVAEEQFPFLILGKSLSPFIPL
                     VDNDNVQAGFDATEYFIKKGCKRIAFIGGSKKLFVTKDRLTGYEQALKHYKLTTDNNR
                     IYFADEFLEEKGYKFSKRLFKHDPQIDAIITTDSLLAEGVCNYIAKHQLDVPVLSFDS
                     VNPKLNLAAYVDINSLELGRVSLETILQIINDNKNNKQICYRQLIAHKIIEK"
     gene            complement(4229..5029)
                     /locus_tag="VQU30_000547"
     CDS             complement(4229..5029)
                     /locus_tag="VQU30_000547"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000938258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1189 domain-containing protein"
                     /protein_id="HET2446713.1"
                     /translation="MLPYPFSYFSSIWGFRKPLSKRFELNWFQLLFTSIFLISLSMVP
                     IAIQNSSQETYPLETFIDNVYEPLTNEVVQDLSEHATIVDGTLTYTGTASQAPSVVIG
                     PSQIKELPKDLQLHFDTNELVISKESKELTRISYRAIQTESFKSKDSLTQAISKDWYQ
                     QNRIYISLFLVLGASFLFGLNFFIVSLGASLLLYITKKSRLFSFRTFKECYHFILNCL
                     GLPTLITLILGLFGQNMTTLITVQNILFVLYLVTIFYKTHFRDPNYHK"
     gene            complement(5290..6132)
                     /locus_tag="VQU30_000548"
     CDS             complement(5290..6132)
                     /locus_tag="VQU30_000548"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001065636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HET2446714.1"
                     /translation="MNNSIKLKRRLTQSLTYLYLIGLSIVIIYPLLITIMSAFKAGNV
                     SAFKLDTNIDLNFDNFKGLFTETLYGTWYLNTLIIALITMAVQTSIIVLAGYAYSRYN
                     FLARKQSLVFFLIIQMVPTMAALTAFFVMALMLNALNHNWFLIFLYVGGGIPMNAWLM
                     KGYFDTVPMSLDESAKLDGAGHFRRFWQIVLPLVRPMVAVQALWAFMGPFGDYILSSF
                     LLREKEYFTVAVGLQTFVNNAKNLKIAYFSAGAILIALPICILFFFLQKNFVSGLTSG
                     GDKG"
     gene            complement(6134..7426)
                     /locus_tag="VQU30_000549"
     CDS             complement(6134..7426)
                     /locus_tag="VQU30_000549"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000414940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HET2446715.1"
                     /translation="MEKQQPSKAALLSIIPGLGQIYNKQKAKGFIFLGVTIVFVLYFL
                     ALATPELSNLITLGNKPGRDNSLFMLIRGAFHLIFVIVYVLFYFSNIKDAHTIAKRIN
                     NGIPVPRTLKDMIKGIYENGFPYLLIIPSYVAMTFAIIFPVIVTLMIAFTNYDFQHLP
                     PNKLLDWVGLTNFTNIWSLSTFRSAFGSVLSWTIIWALAASTLQIVIGIFTAIIANQP
                     FIKGKRIFGVIFLLPWAVPAFITILTFSNMFNDSVGAINTQVLPILAKFLPFLDGALI
                     PWKTDPTWTKIALIMMQGWLGFPYIYVLTLGILQSIPNDLYEAAYIDGANAWQKFRNI
                     TFPMILAVAAPTLISQYTFNFNNFSIMYLFNGGGPGSVGGGAGSTDILISWIYRLTTG
                     TSPQYSMAAAVTLIISIIVISISMIAFKKLHAFDMEDV"
     gene            complement(7537..8808)
                     /locus_tag="VQU30_000550"
     CDS             complement(7537..8808)
                     /locus_tag="VQU30_000550"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000095461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HET2446716.1"
                     /translation="MSSKFMKSTAVLGTATLASLLLVACGSKTADKPADSGSSEVKEL
                     TVYVDEGYKSYIEEVAKAYEKEAGVKVTLKTGDALGGLDKLSLDNQSGNVPDVMMAPY
                     DRVGSLGSDGQLSEVKLSDGAKTDDTTKSLVTAANGKVYGAPAVIESLVMYYNKDLVK
                     DAPKTFADLENLAKDSKYAFAGEDGKTTAFLADWTNFYYTYGLLAGNGAYVFGQNGKD
                     AKDIGLANDGSIVGINYAKSWYEKWPKGMQDTEGAGNLIQTQFQEGKTAAIIDGPWKA
                     QAFKDAKVNYGVATIPTLPNGKEYAAFGGGKAWVIPQAVKNLEASQKFVDFLVATEQQ
                     KVLYDKTNEIPANTEARSYAEGKNDELTTAVIKQFKNTQPLPNISQMSAVWDPAKNML
                     FDAVSGQKDAKTAANDAVTLIKETIKQKFGE"
     gene            9358..10875
                     /gene="malQ"
                     /locus_tag="VQU30_000551"
     CDS             9358..10875
                     /gene="malQ"
                     /locus_tag="VQU30_000551"
                     /EC_number="2.4.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001847831.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-alpha-glucanotransferase"
                     /protein_id="HET2446717.1"
                     /translation="MKKRQSGVLMHISSLPGAYGIGSFGQSAYDFVDFLVRTKQRYWQ
                     ILPLGATSYGDSPYQSFSAFAGNTHFIDLDILVEQGLLEASDLEGVDFGSDASEVDYA
                     KIYYARRPLLEKAVKRFFEVGDVKDFEKFAQDNQSWLELFAEYMAIKEYFDNLAWTEW
                     PDADARARKASALESYREQLADKLVYHRVTQYFFFQQWLKLKAYANDNHIEIVGDMPI
                     YVAEDSSDMWANPHLFKTDVNGKATCIAGCPPDEFSVTGQLWGNPIYDWEAMDKDGYK
                     WWIERLRESFKIYDIVRIDHFRGFESYWEIPAGSDTAAPGEWVKGPGYKLFAAVKEEL
                     GELNIIAEDLGFMTDEVIELRERTGFPGMKILQFAFNPEDESIDSPHLAPANSVMYTG
                     THDNNTVLGWYRNEIDDATREYMARYTNRKEYETVVHAMLRTVFSSVSFMAIATMQDL
                     LELDEAARMNFPSTLGGNWSWRMTEDQLTPAVEEGLLDLTTIYRRINENLVDLKK"
     gene            10901..13159
                     /locus_tag="VQU30_000552"
     CDS             10901..13159
                     /locus_tag="VQU30_000552"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000950172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycogen/starch/alpha-glucan phosphorylase"
                     /protein_id="HET2446718.1"
                     /translation="MLSLQEFVQNRYNKTIAECSNEELYLALLNYSKLASSQKPVNTG
                     KKKVYYISAEFLIGKLLSNNLINLGLYDDVKKELAAAGKDLIEVEEVELEPSLGNGGL
                     GRLAACFIDSIATLGLNGDGVGLNYHFGLFQQVLKNNQQETIPNAWLTEQNWLVRSSR
                     SYQVPFADFTLTSTLYDIDVTGYETATKNRLRLFDLDSVDSSIIKDGINFDKTDIARN
                     LTLFLYPDDSDRQGELLRIFQQYFMVSNGAQLIIDEAIEKGSNLHDLADYAVVQINDT
                     HPSMVIPELIRLLTARGIDLDEAISIVRSMTAYTNHTILAEALEKWPLEFLQEVVPHL
                     VPIIEELDRRVKAEYKDPAVQIIDESGRVHMAHMDIHYGYSVNGVAALHTEILKNSEL
                     KAFYDLYPEKFNNKTNGITFRRWLMHANPRLSHYLDEILGDGWHHEADELEKLLSYED
                     KAAVKEKLESIKAHNKRKLARHLKEHQGVEINPNSIFDIQIKRLHEYKRQQMNALYVI
                     HKYLDIKAGNIPARPITIFFGGKAAPAYTIAQDIIHLILCMSEVIANDPAVAPHLQVV
                     MVENYNVTAASFLIPACDISEQISLASKEASGTGNMKFMLNGALTLGTMDGANVEIAE
                     LVGEENIYIFGEDSETVIDLYAKAAYKSSEFYAREAIKPLVDFIVSDAVLAAGNKERL
                     ERLYNELINKDWFMTLLDLEDYIKVKEQMLADYEDRDAWLDKVIVNISKAGFFSSDRT
                     IAQYNEDIWHLN"
     gene            complement(14203..14775)
                     /locus_tag="VQU30_000553"
     CDS             complement(14203..14775)
                     /locus_tag="VQU30_000553"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2446719.1"
                     /translation="MNKLMKFISVFLTSIVLIVSAIPSVSAVYASEQVSQIETNMELQ
                     PVTSLTEEQINTLANEIQSFHPDVSQQWIKEVINRQLQGDYTIPPTYSPFRAAWQGIT
                     VNQMGALLDTAIALALGGTTAGLANLIKVKGKHAAKSAIRSAISRYLGSWFVNDVALE
                     FAINLLSPGTYLAQLWDKNDAIPNNGRINF"
     gene            complement(15397..16245)
                     /locus_tag="VQU30_000554"
     CDS             complement(15397..16245)
                     /locus_tag="VQU30_000554"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001095523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methyltransferase domain-containing protein"
                     /protein_id="HET2446720.1"
                     /translation="MNTNLKPKLQRFASATAFACPICQENLTLLETNFKCCNRHSFDL
                     AKFGYVNLAPQIKQSANYDKENFQNRQQILEAGFYQAILDAVSDLLASSKTTTTILDI
                     GCGEGFYSRKLQESHSEKTFYAFDISKDSVQIAAKSEPNWAVNWFVGDLARLPIKDAN
                     MDILLDIFSPANYGEFRRVLSKDGILIKVIPTENHLKEIRQRVQDQLTNKEYSNQDIK
                     EHFQEHFTILSSQTASLTKTITAEQLQALLSMTPLLFHVDQSKIDWSQLTEITIEAEI
                     LVGKAF"
     gene            16390..16668
                     /locus_tag="VQU30_000555"
     CDS             16390..16668
                     /locus_tag="VQU30_000555"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003075836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2446721.1"
                     /translation="MLKEVLTVAKVAKKSSLFLGGVAFGTLGLKILASKEAKKGYSKA
                     LAKAYKLKDELDASVSVVKQHGDDVLQDAKYLYEQEKKEEQLDSLIGE"
     gene            16670..18733
                     /locus_tag="VQU30_000556"
     CDS             16670..18733
                     /locus_tag="VQU30_000556"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000008803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heavy metal translocating P-type ATPase"
                     /protein_id="HET2446722.1"
                     /translation="MSFKVLHRGYQHIRLSSSFSLTLDIQDYLRSLARDEKGIESIQF
                     YMDQQHFTLRIKEGFSVLDNAEAFLKRIDKGKVSELMTLPIRREESAYSIVSGAAVKR
                     VLFRSFVPYPIRYIWTCYQALGYIREAYQTLARKELTMEVLDCSAILLSLFMNQSKTA
                     SNIMFMLDLGNHLDQWSLKKTATDLEQSLLAKESDVFLVQGDTVVSIKSSDVQIGDVL
                     ILSQGNEILFDGQVVSGLGMVNESSLTGESFPVEKRESDLVCANTVLETGELRIRVTD
                     NQMNSRILQLIELMKKSEENKKTKQRYFIKMADKVVKYNFLGAGLTYLLTGSFSKAIS
                     FLLVDFSCALKISTPVAYLTVIKEGLNREMVIKDGDVLEKYLEVDTFLFDKTGTITTS
                     YPIVEKVLPFGDYSEEDILRISACLEEHIYHPIANAIVKQAEIEGIEHEEMHGKLQYI
                     ASKGIKSHIDGQPVLIGNYVLMQDEQIHISSEQNALIEEYKSHYNLLFLAYQNELIGM
                     FCIHTPLRKEAKTALDKLKAQGKKLILATGDTLIRTEELVKDLPFDQVYTDLKPDGKF
                     ELVEKLQKAGHTILMVGDGLNDSAALTLSDIGVVMNESADISKQMSDILLLDNRLDFF
                     QELDSLSSSLQTLIKKNIQDTVVVNSSLIGFGLFNWFSPSNLSILHNLTTLRIVLRSL
                     SIKNR"
     gene            complement(18811..20067)
                     /locus_tag="VQU30_000557"
     CDS             complement(18811..20067)
                     /locus_tag="VQU30_000557"
                     /EC_number="6.1.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000546895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine--tRNA ligase"
                     /protein_id="HET2446723.1"
                     /translation="MHIFDELKERGLIFQTTDEEALRKALEEGQVSYYTGYDPTADSL
                     HLGHLVAILTSRRLQLAGHKPYALVGGATGLIGDPSFKDAERSLQTKDTVDGWVKSIQ
                     GQLSRFLDFENGENKAVMVNNYDWFGSISFIDFLRDIGKYFTVNYMMSKESVKKRIET
                     GISYTEFAYQIMQGYDFFVLNQDHNVTLQIGGSDQWGNMTAGTELLRRKADKTGHVIT
                     VPLITDATGKKFGKSEGNAVWLNPEKTSPYEMYQFWMNVMDADAVRFLKIFTFLSLDE
                     IEDIRKQFEAAPHERLAQKVLAREVVTLVHGEEAYKEALNITEQLFAGNIKNLSVKEL
                     KQGLRGVPNYQVQADENNNIVELLVSSGIVNSKRQAREDVQNGAIYVNGDRIQDLDYV
                     LSDADKLENELTVIRRGKKKYFVLTY"
     gene            20209..22674
                     /locus_tag="VQU30_000558"
     CDS             20209..22674
                     /locus_tag="VQU30_000558"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866735.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein"
                     /protein_id="HET2446724.1"
                     /translation="MQNQLNELKRKMLEFFQQKQKNKKSARPGKKGSSTKKSKTLDKS
                     AIFPAILLSIKALFNLLFVLGFLGGMLGVGIALGYGVALFDKVRVPQTEELVNQVKDI
                     SSISEITYSDGTVIASIESDLLRTSISSEQISENLKKAIIATEDEHFKEHKGVVPKAV
                     IRATLGKFVGLGSSSGGSTLTQQLIKQQVVGDAPTLARKAAEIVDALALERAMNKDEI
                     LTTYLNVAPFGRNNKGQNIAGARQAAEGIFGVDASQLTVPQAAFLAGLPQSPITYSPY
                     ENTGELKSDEDLEIGLRRAKAVLYSMYRTGALSKDEYSQYKDYDLKQDFLPSGTVTGI
                     SRDYLYFTTLAEAQERMYDYLAQRDNVSAKELKNEATQKFYRDLAAKEIENGGYKITT
                     TIDQKIHSAMQSAVADYGYLLDDGTGRVEVGNVLMDNQTGAILGFVGGRNYQENQNNH
                     AFDTKRSPASTTKPLLAYGIAIDQGLMGSETILSNYPTNFANGNPIMYANSKGTGMMT
                     LGEALNYSWNIPAYWTYRMLREKGVDVKGYMEKMGYEIPEYGIESLPMGGGIEVTVAQ
                     HTNGYQTLANNGVYHQKHVISKIEAADGRVVYEYQDKPVQVYSKATATIMQGLLREVL
                     SSRVTTTFKSNLTSLNPTLANADWIGKTGTTNQDENMWLMLSTPRLTLGGWIGHDDNH
                     SLSRRAGYSNNSNYMAHLVNAIQQASPSIWGNERFALDPSVVKSEVLKSTGQKPGKVS
                     VEGKEVEVTGSTVTSYWANKSGAPATSYRFAIGGSDADYQNAWSSIVGSLPTPSSSSS
                     SSSSSSDSSNSSTTRPSSSRARR"
     gene            22739..23650
                     /locus_tag="VQU30_000559"
     CDS             22739..23650
                     /locus_tag="VQU30_000559"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007285066.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DMT family transporter"
                     /protein_id="HET2446725.1"
                     /translation="MNQYQKKIVNGKIYSLLSGLIWGICGILGEYFFTHYQVSSGWIT
                     SMRLTLAGSLVLIWSAIQLKSQVLDIWRDKKNYLPFLAYAILGIFSVQYFFYLCLEYS
                     NATTATILQFISPVFILFYNRLVYQKRASKSAVFYVLVAMLGVCLMATKGDLSQLSMT
                     PLALITGLLSAMGVMFNVILPQPFAKRYGFVPTVGWGMILAGLFSNVLSPVYQLSFTL
                     DIWSILICLIIAFFGTAFAFFISMKAVSLVSPLVVSVISASEPLSSALLSVLFLGLVV
                     DWSLLLAIALIILPMIFLSIEEAKESR"
     gene            23880..24578
                     /gene="dapD"
                     /locus_tag="VQU30_000560"
     CDS             23880..24578
                     /gene="dapD"
                     /locus_tag="VQU30_000560"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2,3,4,5-tetrahydropyridine-2,6-dicarboxylate
                     N-acetyltransferase"
                     /protein_id="HET2446726.1"
                     /translation="MTATKMNAQEIIQFIANAEKKTSVKVTFEGQLATAVPSSVVKLG
                     NVLFGDWKDVAPLLEGLVENQDYVVEQDARNSAVPLLDKRAINARIEPGAIIRDQVEI
                     GDNAVIMMGAVINIGAEIGAGTMIDMGAILGGRAIVGKNSHVGAGAVLAGVIEPASAE
                     PVCVGDNVLIGANAVVIEGVQIGSGSVVAAGAIVTQDVPENVVVAGVPARIIKEIDAQ
                     TQQKTALEDALRTL"
     gene            24646..25776
                     /locus_tag="VQU30_000561"
     CDS             24646..25776
                     /locus_tag="VQU30_000561"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006151341.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetyldiaminopimelate deacetylase"
                     /protein_id="HET2446727.1"
                     /translation="MLDLIQTRRALHQIPEIGLEEFKTQAYLLDVIEKLTTGKDFVQI
                     RTWRTGILVYLQGSQPERTIGWRTDIDGLPIVEQTGLPFTSQHQGRMHACGHDFHMTI
                     ALGCLERALEEQPKNNLLFLFQPAEENEAGGMLMYEDGAFGDWLPNQFYGLHVRPDLK
                     VGQIATNTHTLFAGTCEVKIRFKGKGGHAAFPHEANDALVAASYFVTQVQSVVSRNVN
                     PIEGAVVTFGVFQAGTTNNVITDTAFLHGTIRALTQDMSLLVQKRVKTVAEGVAAAFD
                     MEVEVELKQGGYLPVENNPALARELMDFFDEKDGIELIDIEPAMTGEDFGYLLSKVDG
                     VMFWLGIDSPYALHHPQMSPKEEVLAIGVAAVSSFLKKKAAE"
     gene            25788..26327
                     /locus_tag="VQU30_000562"
     CDS             25788..26327
                     /locus_tag="VQU30_000562"
                     /EC_number="6.3.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863197.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-formyltetrahydrofolate cyclo-ligase"
                     /protein_id="HET2446728.1"
                     /translation="MKSELRKQVLHEMKAISQEQKQAIDQALTERILQHPFYQEAKVI
                     ATYLSFSHEFQTRELIEQALKDGKKVLTPKTYPKGRMDFVVYDPQQLVKTSFALLEPQ
                     GDLEVVDASQIDLIHVPGLAFTTDGYRIGYGGGYYDRYLEHFSGRALSTIYPCQIQDF
                     IPENHDIPVQEVLIDEGNL"
     gene            26311..26988
                     /locus_tag="VQU30_000563"
     CDS             26311..26988
                     /locus_tag="VQU30_000563"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhomboid family intramembrane serine protease"
                     /protein_id="HET2446729.1"
                     /translation="MKEIFDRRYPVTSFFLLVTALVFLLMLVTAGGNFDRADTLFRFG
                     AMYGPAIRLFPEQVWRLLSAIFVHIGWEHFIVNMLSLYYLGRQVEEIFGSKQFFFLYL
                     LSGMMGNLFVFVFSPKSLAAGASTSLYGLFAAIIVLRYATRNPYIQQLGQSYLTLFVV
                     NIIGSVLIPGISLAGHIGGAVGGAFLAVIFPVRGEKRMYNTSQRLGAVVLFVGLAILL
                     FYKGMGM"
     gene            complement(27060..27959)
                     /gene="galU"
                     /locus_tag="VQU30_000564"
     CDS             complement(27060..27959)
                     /gene="galU"
                     /locus_tag="VQU30_000564"
                     /EC_number="2.7.7.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000202216.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UTP--glucose-1-phosphate uridylyltransferase
                     GalU"
                     /protein_id="HET2446730.1"
                     /translation="MTSKVRKAVIPAAGLGTRFLPATKALAKEMLPIVDKPTIQFIVE
                     EALKSGIEDILVVTGKSKRSIEDHFDSNFELEYNLKEKGKTDLLKLVDKTTDMRLHFI
                     RQTHPRGLGDAVLQAKAFVGNEPFVVMLGDDLMDITDEKAVPLTKQLMDDYERTHAST
                     IAVMPVPHDEVSAYGVIAPQGEGKDGLYSVETFVEKPAPEDAPSDLAIIGRYLLTPEI
                     FQILENQAPGAGNEIQLTDAIDTLNKTQRVFAREFNGARYDVGDKFGFMKTSIDYALK
                     HPQVKDDLKNYLIQLGKELTEKE"
     gene            complement(27981..28997)
                     /locus_tag="VQU30_000565"
     CDS             complement(27981..28997)
                     /locus_tag="VQU30_000565"
                     /EC_number="1.1.1.94"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000415108.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent glycerol-3-phosphate
                     dehydrogenase"
                     /protein_id="HET2446731.1"
                     /translation="MEKQTVAVLGPGSWGTALSQVLNDNGHEVRIWGNLPEQINEINT
                     YHTNKHYFKDVVLDENIIAYTDLAETLKDVDAILFVVPTKVTRLVAQQVAQTLDHKAI
                     IMHASKGLEPDSHKRLSTILEEEIPEQLRSDIVVVSGPSHAEETIVRDLTLITAASKD
                     LQTAQYVQELFSNHYFRLYTNTDVIGVETAGALKNIIAVGAGALHGLGFGDNAKAAII
                     ARGLAEITRLGVALGASPLTYSGLSGVGDLIVTGTSIHSRNWRAGDALGRGESLADIE
                     ANMGMVIEGISTTRAAYELAQELGVYMPITQAIYQVIYHGTNIKDAIYDIMNNEFKAE
                     NEWS"
     gene            29209..29586
                     /locus_tag="VQU30_000566"
                     /pseudo
     CDS             29209..29586
                     /locus_tag="VQU30_000566"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809823.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
     gene            complement(29766..30191)
                     /locus_tag="VQU30_000567"
     CDS             complement(29766..30191)
                     /locus_tag="VQU30_000567"
                     /inference="COORDINATES: protein motif:HMM:NF025080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HET2446732.1"
                     /translation="MNNLSSVDSEELFQFYRERGNAENFIKERKAGFFGDKTDSSTMI
                     KNEVRMMMGCLAYNLYLFLKQLAGDEVKSLTIKRFRRLFLHIAGKYVSTARRHILKFS
                     SLYAYSKQFQALFDTICQINLILPVPYRARGQGKTCLTE"
     gene            complement(30259..30909)
                     /gene="phoU"
                     /locus_tag="VQU30_000568"
     CDS             complement(30259..30909)
                     /gene="phoU"
                     /locus_tag="VQU30_000568"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001245788.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate signaling complex protein PhoU"
                     /protein_id="HET2446733.1"
                     /translation="MRNQFDLELHELEQSFLGLGQLVLETASKALLALASKDKEMAEL
                     IINKDHAINQGQSAIELTCARLLALQQPQVSDLRFVISIMSSCSDLERMGDHMAGIAK
                     AVLQLKENQLAPDEEQLHQMGKLSLSMLADLLVAFPLHQASKAISIAQKDEQIDQYYY
                     ALSKEIIGLMKDQETSIPNGTQYLYIIGHLERFADYIANICERLVYLETGELVDLN"
     gene            complement(30924..31676)
                     /gene="pstB"
                     /locus_tag="VQU30_000569"
     CDS             complement(30924..31676)
                     /gene="pstB"
                     /locus_tag="VQU30_000569"
                     /EC_number="7.3.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003101281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter ATP-binding protein"
                     /protein_id="HET2446734.1"
                     /translation="MGTFSVRHLDLFYGDFQALKNISIQLPERQITALIGPSGCGKST
                     FLKTLNRMNDLVPSCHIEGQVLLDEQDIYSSKFNLNQLRKRVGMVFQQPNPFAMSIYD
                     NVAYGPRTHGIRDKKQLDALVEKSLKGAAIWEEVKDDLKKSAMSLSGGQQQRLCIARA
                     LAVEPDVLLMDEPTSALDPISTLKIEDLIQQLKKDYTIIIVTHNMQQASRISDKTAFF
                     LTGEICEFGDTVDVFTNPKDQRTEDYISGRFG"
     gene            complement(31678..32493)
                     /gene="pstA"
                     /locus_tag="VQU30_000570"
     CDS             complement(31678..32493)
                     /gene="pstA"
                     /locus_tag="VQU30_000570"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015057412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease PstA"
                     /protein_id="HET2446735.1"
                     /translation="MSKYLLKLLVYCFSALTFGSLFLIIGFILIKGLPHLSLSLFSWT
                     YTSENISLMPAIISTVILVFGALLLALPIGIFAGFYLVEYTKKDSLCVKIMRLASDTL
                     SGIPSIVFGLFGMLFFVVFLGFQYSLLSGILTSVIMVLPVIIRSTEEALLSVSDSMRQ
                     ASYGLGAGKLRTVFRIVLPVAMPGILAGVILAIGRIVGETAALMYTLGTSTNTPSSLM
                     SSGRSLALHMYMLSSEGLHVNEAYATGVILIITVLMINTLSSLLSRKLVKGAS"
     gene            complement(32486..33349)
                     /gene="pstC"
                     /locus_tag="VQU30_000571"
     CDS             complement(32486..33349)
                     /gene="pstC"
                     /locus_tag="VQU30_000571"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000595184.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease subunit PstC"
                     /protein_id="HET2446736.1"
                     /translation="MTKQAFKEAVFRAIFFMSATVAVVAILLICFFIFSNGLPFMANY
                     GFARFLLGSDWSPTNIPASYGILPMIVGSLLITLGAIVIGVPTGILTSVFMVYYCPKP
                     VYGFLKSAINLMAAIPSIVYGFFGLQLLVPWIRTFLGNGMSVLTASLLLGIMILPTII
                     SLSESAIRTVPKTYYSGSLALGASHERSIFSVILPAARSGILSAVILGIGRAVGETMA
                     VILVAGNQPIIPSGLFSGTRTLTTNIVLEMAYASGQHREALIATSAVLFFLILLINAY
                     FAYLKGKSSYE"
     gene            complement(33467..34342)
                     /locus_tag="VQU30_000572"
     CDS             complement(33467..34342)
                     /locus_tag="VQU30_000572"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000669496.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate-binding protein"
                     /protein_id="HET2446737.1"
                     /translation="MKFKKMLTLAAIGLSGFGLVACGNQSAASKQSASGTIEVISREN
                     GSGTRGAFTEITGILKKDGDKKIDNTAKTAVIQNSTEGVLSAVQGNANAIGYISLGSL
                     TKSVKALEIDGVKASRDTVLDGEYPLQRPFNIVWSSNLSKLGQDFISFIHSKQGQQVV
                     TDNKFIEAKTETTEYTSQHLSGKLSVVGSTSVSSLMEKLAEAYKKENPEVTIDITSNG
                     SSAGITAVKEKTADIGMVSRELTPEEGKSLTHDAIALDGIAVVVNNDNKASQVSMAEL
                     ADVFSGKLTTWDKIK"
     gene            complement(34509..35840)
                     /locus_tag="VQU30_000573"
     CDS             complement(34509..35840)
                     /locus_tag="VQU30_000573"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000833277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component sensor histidine kinase"
                     /protein_id="HET2446738.1"
                     /translation="MKRYLQFWLVNLSVSLILIAGMALTWISKGIGLFLLALSLGQGG
                     YWLFCLWKWEVAFETLHQPLLTSSEYFLEKGQEDLKSLAQYVSALKTKVSQQDQQYKD
                     LAETMEVLLSHLTMGTFLVSAQGQMLLSSRSLPHYFPDVDGDISSLDDLKRMDIRNLV
                     HQAFDQKTRLKQEVSGFHEGDLILEVTAVPVFSPTQSVEAVLVLLYDLTTIRTYEKLN
                     LAFVSNASHELRTPVTSIKGFAETIKGMSAEEEALKDDFLDIIYKESLRLEHIVEHLL
                     TLSKAQQMPIQWTTLSLAEFVQDLTQSLQPQLKKKDLQLKVQVPDDVTLVSDSQLLSQ
                     ILLNLLSNAIRYTEQGGKIEVKTQKVNEGIKISVSDTGIGISQLEQDRIFERFYRVNK
                     GRSRQTGGTGLGLAIVKELSQLLGGQVTVTSQLGRGSCFTIFLPNQSFAQD"
     gene            complement(35841..36548)
                     /locus_tag="VQU30_000574"
     CDS             complement(35841..36548)
                     /locus_tag="VQU30_000574"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000166478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HET2446739.1"
                     /translation="MTKQVLLVDDEEHILKLLDYHLSKEGFSTQLVTNGRKALALAET
                     EPFDFILLDIMLPQLDGMEVCKRLRAKGVKTPIMMVSAKSDEFDKVLALELGADDYLT
                     KPFSPRELLARVKAVLRRTKGEQEGDDSDNIADDSWLFGTLKVYPERHEVYKANKLLS
                     LTPKEFELLLYLMKHPNMTLTRERLLERIWGYDFGQETRLVDVHIGKLREKIEDNPKA
                     PQFIRTIRGYGYKFKEL"
     gene            complement(36632..37117)
                     /locus_tag="VQU30_000575"
     CDS             complement(36632..37117)
                     /locus_tag="VQU30_000575"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001855144.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cupin domain-containing protein"
                     /protein_id="HET2446740.1"
                     /translation="MAPTDKEDLIRTLELAPHVEGGYFRQTKKASDTINLAGKGRALY
                     TSIYFLLEETNPSHFHRLTADEIWYFHAGSPLTVHMITADGHYEAVTLGLDISKGQQL
                     HYCVPKGTIWGSTVDKDYALVSCLVAPGFEFEDFELFERVDLLATYPEHKEMIERLTR
                     Y"
     gene            37103..37660
                     /locus_tag="VQU30_000576"
                     /pseudo
     CDS             37103..37660
                     /locus_tag="VQU30_000576"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(37996..39687)
                     /locus_tag="VQU30_000577"
     CDS             complement(37996..39687)
                     /locus_tag="VQU30_000577"
                     /EC_number="6.1.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009729659.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine--tRNA ligase"
                     /protein_id="HET2446741.1"
                     /translation="MNTKELIASELASIIDSLDQEAILKLLETPKNSEMGDIAFPAFS
                     LAKVERKAPQMIAAELAEKMNSQAFEKVVATGPYVNFFLDKSAISAQVLQAVTTEKEH
                     YADQNIGKQENVVIDMSSPNIAKPFSIGHLRSTVIGDSLSHIFQKIGYQTVKVNHLGD
                     WGKQFGMLIVAYKKWGDEEAVKAHPIDELLKLYVRINAEAENDPSLDEEAREWFRKLE
                     NGDEEALALWQWFRDESLVEFNRLYNELKVEFDSYNGEAFYNDKMDAVVDILSEKGLL
                     LESEGAQVVNLEKYGIEHPALIKKSDGATLYITRDLAAALYRKNEYQFAKSIYVVGQE
                     QSAHFKQLKAVLQEMGYDWSDDITHVPFGLVTKEGKKLSTRKGNVILLEPTVAEAVSR
                     AKVQIEAKNPELENKDQVAHAVGVGAIKFYDLKTDRTNGYDFDLEAMVSFEGETGPYV
                     QYAYARIQSILRKADFKPETAGNYSLNDTESWEIIKLIQDFPRIINRAADNFEPSIIA
                     KFAISLAQSFNKYYAHTRILDESPERDSRLALSYATAVVLKEALRLLGVEAPEKM"
     gene            39823..40269
                     /gene="argR"
                     /locus_tag="VQU30_000578"
     CDS             39823..40269
                     /gene="argR"
                     /locus_tag="VQU30_000578"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001227366.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine repressor"
                     /protein_id="HET2446742.1"
                     /translation="MRKRDRHQLIKKMITEEKLSTQKEIQDRLEAHNVCVTQTTLSRD
                     LREIGLTKVKKNDMVYYVLVNETEKIDLVEFLSHHLEGVARAEFTLVLHTKLGEASVL
                     ANIVDVNKDEWILGTVAGANTLLVICRDQHVAKLMEDRLLDLMKDK"
     gene            40320..42854
                     /gene="mutS"
                     /locus_tag="VQU30_000579"
     CDS             40320..42854
                     /gene="mutS"
                     /locus_tag="VQU30_000579"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399485.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA mismatch repair protein MutS"
                     /protein_id="HET2446743.1"
                     /translation="MAIEKLSPGMQQYVDIKKQYPDAFLLFRMGDFYELFYEDAVNAA
                     QILEISLTSRNKNADNPIPMAGVPYHSAQQYIDVLIEQGYKVAIAEQMEDPKQAVGVV
                     KREVVQVITPGTVVDSSKLDSQNNFLVAIDREGNQFGLAYMDLVTGDFYVTGLLDFTL
                     VCGEIRNLKAREVVLGYDLSEEEEQILSCQMNLVLSYEKESFEDLHLLDLRLATVEQT
                     ASSKLLQYVHRTQMRELNHLKPVIRYEIKDFLQMDYATKASLDLVENARSGKKQGSLF
                     WLLDETKTAMGMRLLRSWIHRPLIDKERIVQRQEVVQVFLDHFFERSDLTDSLKGVYD
                     IERLASRVSFGKTNPKDLLQLATTLSSVPRIRAILEGMEQPALAYLIAQLDAIPELES
                     LISAAIAPEAPHVITDGGIIRTGFDETLDKYRCVLREGTSWIAEIEAKERENSGISTL
                     KIDYNKKDGYYFHVTNSQLGNVPAHFFRKATLKNSERFGTEELARIEGDMLEAREKSA
                     NLEYEIFMRIREEVGKYIQRLQALAQGIATVDVLQSLAVVAETQHLIRPEFGDDSQID
                     IRKGRHAVVEKVMGAQTYIPNTIQMAEDTSIQLITGPNMSGKSTYMRQLAMTAVMAQL
                     GSYVPAESAHLPIFDAIFTRIGAADDLVSGQSTFMVEMMEANNAISHATKNSLILFDE
                     LGRGTATYDGMALAQSIIEYIHEHIGAKTLFATHYHELTSLESSLQHLVNVHVATLEQ
                     DGQVTFLHKIEPGPADKSYGIHVAKIAGLPADLLARADKILTQLENQGTENPPPMRQT
                     SAVTEQISLFDRAEEHPILAELAKLDVYNMTPMQVMNVLVELKQKL"
     gene            43001..44695
                     /gene="patA"
                     /locus_tag="VQU30_000580"
     CDS             43001..44695
                     /gene="patA"
                     /locus_tag="VQU30_000580"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000908145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux ABC transporter subunit PatA"
                     /protein_id="HET2446744.1"
                     /translation="MLIQKIKTYKWQALASLLMTGLMVASSLLQPRYLQEVLGALLTG
                     KYEAIYSIGAWLIGVAVVGLVAGGLNVVLAAYIAQGVSSDLREDAFRKIQTFSYADIE
                     QFNAGNLVVRMTNDINQIQNVVMMTFQILFRLPLLFIGSFILAVQTLPSLWWVIVLMV
                     VLIFGLTAVMMGMMGPRFAKFQTLLERINAIAKENLRGVRVVKSFVQEKEQFAKFTEV
                     SDELLGQNLYIGYAFSVVEPFMMLVGYGAVFLSIWLVAGMVQSDPSVVGSIASFVNYL
                     SQIIFTIVMVGFLGNSVSRAMISMRRIREILDAEPAMTFKDVPDEELVGSLSFENVTF
                     TYPMDKEPMLKDVSFTIEPGQMVGVVGATGAGKSTLAQLIPRLFDPQEGAIKIGGKDI
                     REVSEGTLRKTVSIVLQRAILFSGTIADNLRQGKGNATLFEMERAANIAQASEFIHRM
                     EKTFESPVEERGTNFSGGQKQRMSIARGIVSNPRILIFDDSTSALDAKSERLVQEALN
                     KDLKGTTTIIIAQKISSVVHADKILVLNQGRLIGQGTHADLVANNAVYREIYETQK"
BASE COUNT        13056 a         8549 c         9839 g        13525 t
ORIGIN      
        1 ggttttgagg ttgtagatga aactgacgaa gtcagtaaca atacctacgg taaggcgacg
       61 ctgacgtggt ttgaagagat tttcgaagag tattagcgct aatttttagg gctttcacct
      121 gacttttaaa gactggcaaa cttttctgat gattttcatg aagagcctgc gcttttatgg
      181 taaaatagta acagaataaa agaggagaga aataatgaaa cgtagtatgt atgctggtcg
      241 tgttcgtgag gaacacatcg gacaagaaat aaccttgaaa ggatgggttg gccgtcgtcg
      301 tgaccttggt ggtttgatct ttatcgatct tcgtgaccgt gaaggaatca tgcagttggt
      361 tatcaaccct gaaaaagtat ctgcagaggt tatggcaaca gctgaaagcc ttcgtagcga
      421 atttgttatt gaggtgactg gtcaggtcgc tgcgcgtgag caagccaatg ataagttgcc
      481 aactggtgcg gttgagttaa acgtgacagc tcttattgtg cttaacacag ctaagacaac
      541 accatttgag attaaggatg gcattgaggc aaatgacgat acacgtttgc gttaccgtta
      601 ccttgacctt cgtcgtccag aaatgttgga aaatcttaaa cttcgtgcca aggtgaccca
      661 ctctatccgc aactatttgg atgagttgga gtttatcgac gtggagacac cattcctttc
      721 taagtcaacg cctgaagggg cgcgtgatta tttagtgccg tctcgtgtta ataaggggca
      781 tttttacgct cttcctcaaa gtccacaaat cacgaaacag ctcttgatga atgctggttt
      841 tgaccgttac taccaaatcg ttaaatgttt ccgtgacgag gacttgcgtg gagaccgcca
      901 gcctgaattt actcaggtcg acttggaaac gtccttcctt actgagaaag aaatccaaga
      961 tattacagaa ggcttgatcg cgcgcgtgat gaaggaaaca aaaggcatcg aagtaacgct
     1021 accgttccct cgtatgaaat acgatgatgc tatggctctt tacggttctg acaagccaga
     1081 tactcgtttt gacatgttgc ttcaggactt gacagaagtg gtcaaaggtg tagactttaa
     1141 agtcttttca gaagcacctg ctgtaaaagc gattgtggtc aaaggagctg cggacaacta
     1201 ttcacgtaaa gacatcgaca agatgacgga agtagccaaa cagtatggtg ccaaaggtct
     1261 tgcttgggtc aaggtggttg atggagaatt aaacggacca gttgccaagt tcttgactgg
     1321 tatccaagaa gaattgacaa cagcgcttgc tcttgaagat aaggacttgg ttctctttgt
     1381 ggcggatacg cttgaagtgg ttaatgcaac actgggtacc cttcgtggac gtattgctaa
     1441 agagcttggc ttgattgata atgataagtt caacttcctt tgggtggttg actggccgat
     1501 gtttgaatgg tctgaagaag aaggccgcta catgagcgcc caccatccat tcacacttcc
     1561 acaggaagag actgctcacg aattagaagg tgatttggct aaggttcgtg ccattgctta
     1621 cgatatcgtc ttgaacggtt atgagcttgg tggtggtagc cttcgtatca accaaaaaga
     1681 ccttcaagaa cgcatgttca aggctcttgg tttctcaact gaagaagcca atgaccagtt
     1741 tggtttcctt cttgaagcca tggactatgg tttcccaccg cacggtggtt tggctatcgg
     1801 gcttgaccgt tttgtcatgt tgcttgctgg agaagaaaat atccgtgaag tcattgcctt
     1861 tcctaagaac aacaaggcaa ctgacccaat gacacaagct ccatcaacag tcgctctcaa
     1921 acaactagag gaactcagct tacaagtaga agaagatgaa acaaacaaaa cgaattaagc
     1981 ggtggcgcta ttatctgcgc cgctttgctt atcagataaa aattttacgt gtcttacaaa
     2041 gtatctctcg agaaaagtat gatgagaaga tttcggcctc tctggtctat ggttttttat
     2101 cagcagtagc agttaatttc tttttccaac cagggcatgt gtattcgagt ggtgcaacag
     2161 gtctggcaca gattatctct gccttgagta atcactggtt tggttttcat attccgattt
     2221 cgctaagctt ctacgccatt aacttccctt tgatggtctt agcttggtat cagattggcc
     2281 ataagttcac cgtctttacc tttatcacgg tatctatgag ttccttcttt atccagtttg
     2341 tccctgtggc aaccttgacg gaggatccca ttatcaattc cctttttggg ggtgttgtta
     2401 tgggtttggg gattggtttt gctcttcgaa acaatatctc cagtggtggg acggatatcg
     2461 tcagcctgac tattcgtaag aaaacgggta agaatgtcgg tagtatttct ttcttggtaa
     2521 atggaactat catgctgata gcaggtttga cctttggttg gaaatacgct ctttattcta
     2581 tgattaccat ctttgtctct agccgtgtga cagacgcagt ctttactaag caaaagcgta
     2641 tgcaggccat gattgtgaca aatcatccag agaaggtaat tgaaaaaatc cataaaaaat
     2701 tgcaccgcgg agcaaccatg atccacgatg cagaaggaac ctataatcac gagagaaagg
     2761 cagttttaat cactgtcatt acacgtgcag agtttaatga atttaaacag attatgacac
     2821 aagtggatcc aagctccttt gtctctgtct cggaaaatgt tcatattcta ggaagatttg
     2881 ttgagataga taattagtga ttaatactct tcgaaaatct cttcaaacca cgtcagcttc
     2941 accttgccgt atatatgtta ctgacttcgt cagttctatc tgcaacctca aaaccatgtt
     3001 ttgagctgac ttcgtcagtt tcatctacaa cctcaaaacc atgttttgag caacctgcgg
     3061 ctagcttcct agtttgcact ttgattttca ttgagtataa aaagatcttg ggaaaagact
     3121 caatttcagt agaaaaggaa gtaaatcttc ccacattaaa acgcatagta tcaagttttt
     3181 tcaatacctg atagtatgcg tttttgcttt taacgacttt ttgcccagtc tcttattttt
     3241 cgataatttt gtgggcgatc aattgacggt aacaaatttg tttattgttt ttattatcat
     3301 taataatctg gagaatagtt tcaagggaaa cacgaccaag ctctaaacta ttgatatcga
     3361 cataggctgc caagttgagc ttgggattaa ccgagtcaaa gctgagaaca gggacatcca
     3421 gctggtgttt ggcaatatag ttacaaacgc cttcagctag gaggctatcg gttgtgatga
     3481 tagcatcaat ttgtggatcg tgcttgaata atcgcttgct aaatttatag cccttttctt
     3541 ccagaaactc gtcggcaaag tagatgcgat tgttgtcagt ggtaagtttg taatgtttaa
     3601 gcgcctgttc atagcctgtt aaacggtctt tggtcacgaa gagcttttta cttcctccga
     3661 taaaggcaat gcgtttgcag ccttttttga tgaaatattc agtcgcatca aaaccagctt
     3721 gaacattgtc gttgtcgaca agtgggatga aaggagatag agatttacct aagataagga
     3781 aggggaactg ttcttctgcg acgagtttta cgagagggtc ttcttcttgg gcatagagaa
     3841 agattagccc atctacacgc ttgccgtaga ccatttgtga aatagcgttg agacgctcct
     3901 tctcatcttt ccctgttgct atctgaatgg catagtggtt ttcagatgcg acttgagaga
     3961 tgccacgtag aaccgatgga aagaaaggat tctggtagaa ggcgtctgag tcatcaggaa
     4021 gaactaatcc gataacctga gtatagctgc ttaccaagct acgagcgttg aggtttgggt
     4081 ggtagttgag ttccttcata gctttgcgaa cgcgtttttt tgtttcgtcg ctaatggttg
     4141 atttattttg aataacacgg gttacggttg aaggcgaaac accagcagcc ttggccacgt
     4201 ctttaatcgt aacgggcata aaaatctcct atttatggta atttggatca cggaaatgtg
     4261 ttttataaaa gatagtgacc agatacagaa caaaaagaat attttgtaca gtaatcaggg
     4321 ttgtcatatt ttggccaaat aatcccaaaa taagtgtaat cagagtcggc aatcctaaac
     4381 agttcaagat aaagtgatag cactctttaa aggttctaaa tgaaaagagg cgtgatttct
     4441 tagtgatata aaggagaaga ctagctccta gagagacgat aaagaaattc aaaccaaaga
     4501 ggaagctcgc accgagaact aggaagaggc tgatatagat acgattttgt tggtaccagt
     4561 ctttagaaat tgcttgggtc aagctgtctt tgcttttgaa actctcagtc tgaatggctc
     4621 ggtaagagat gcgggtcagt tccttgcttt ccttgctgat gactagttca tttgtatcga
     4681 aatgcagttg caagtcctta ggtaattcct tgatttgact tggaccaatc acaacagaag
     4741 gggcttgact agctgttcca gtataagtta atgtgccatc gacaattgta gcatgttcag
     4801 agagatcctg gacaacctca tttgtcagag gttcatagac attatcgata aaagtttcta
     4861 gcggataggt ctcctgggag ctgttttgga tagcaatggg taccatagac aagctgataa
     4921 ggaagatact ggtaaagaga agttgaaacc agttgagctc gaaacgtttg gacaggggct
     4981 tacgaaaccc ccaaatactt gaaaaatagg aaaatggata tggaagcata ggtatctttc
     5041 taaaaggtgt tttctatatg agtattatta tatagagaaa tgcgctttat ttcaagtcta
     5101 ggagaaaaat tgcttgctac aaggatatta tttacagtga caattgctaa taatcaatga
     5161 aaatcaaagt gcaaaccagg aagctagctg caggttgctc aaagcacaac tttgaggttg
     5221 gagataaagc tgacgtggtt tgaagagatt ttcgaagagt ataaaatgaa aaagggtggc
     5281 ggggataaat tatcccttgt cgccaccact tgtaagtcct gaaacaaagt tcttttgtag
     5341 aaagaagaag agaatacaga ttggaagggc gatgaggata gcacctgctg agaagtaggc
     5401 aatcttcaag tttttcgcat tgttaacgaa ggtttggaga cctacggcaa cagtaaagta
     5461 ttctttctca cgaagcaaga aactagagag gatgtagtcc ccgaaaggtc ccatgaaggc
     5521 ccagagagct tgtacggcaa ccattgggcg aacaagtggt agaacaattt gccagaagcg
     5581 gcggaagtgt cctgcaccgt ctagttttgc agattcgtct aaagacattg gcactgtatc
     5641 gaagtagcct ttcatgagcc aagcattcat cgggatacca ccaccaacgt agaggaagat
     5701 gaggaaccag ttgtggttaa gggcgttcaa cataagcgcc ataacgaaga aggctgtcaa
     5761 agcggccata gttggcacca tttggatgat caagaagaag accaaacttt gtttacgagc
     5821 caagaagttg taacggctgt aagcataacc agcaagtacg atgatacttg tttgaacagc
     5881 catggtaatt aaggcgataa tcaaagtgtt gaggtaccaa gtaccgtaca aggtttcagt
     5941 gaagaggcct ttaaagttat caaaattgag gtcgatatta gtatctagtt taaaggctga
     6001 gacgttacct gctttaaagg ctgacataat ggtaatcaac agtggataga taattacaat
     6061 tgatagacca atcaggtaaa ggtaagtaag gctttgagtc agtctacgtt tgagtttaat
     6121 tgagttattc atcttagacg tcctccatat caaatgcgtg tagtttcttg aatgcgatca
     6181 tagagattga gatgacaatg atagagataa tcaaggtaac agctgccgcc attgagtatt
     6241 gaggagatgt acctgttgtc aaacggtaga tccatgagat caagatatcg gttgaaccag
     6301 ctccacctcc gacactacca ggtcctccac cattgaagag gtacatgata gagaagttgt
     6361 taaagttgaa ggtgtattgg ctaatcaaag taggtgccgc aacagccaaa atcattggga
     6421 aagtgatgtt gcggaatttt tgccaagcgt tggcaccgtc aatataagct gcttcgtaaa
     6481 ggtcgttagg aatagattgc aagataccca aagtcaaaac gtagatgtat gggaatccga
     6541 gccaaccttg catcataatc aaggcaatct tagtccaagt tgggtctgtt ttccaaggaa
     6601 taagagctcc atcaaggaaa ggaaggaatt tagccaagat tggcaatact tgagtgttga
     6661 tagcaccgac actatcgtta aacatgtttg agaatgtcaa gatagtgatg aaggctggga
     6721 cagcccaagg aagaaggaaa ataacaccaa agatacgttt tcctttgata aatggttggt
     6781 tggcaatgat agctgtgaag ataccaatta cgatttgtaa agtagaagct gccaaagccc
     6841 aaatgatagt ccaagaaaga acagaaccaa aggcagaacg gaaggtactc aagctccaaa
     6901 tgtttgtaaa gttggtcaaa ccaacccagt ccaacaactt gtttggtggc aagtgttgga
     6961 agtcgtagtt ggtaaaggcg atcatcaagg ttacgataac tgggaagata atcgcgaagg
     7021 tcatggcaac ataagatgga atgatcaaga ggtaagggaa gccattttca taaatccctt
     7081 tgatcatgtc tttgagtgtg cgtggaactg gaattccatt gttaatgcgt tttgcaatcg
     7141 tatgtgcatc tttgatattt gagaaataaa agagtacata aacgattaca aagattagat
     7201 ggaaggcacc acgaatcagc ataaagaggg aattatcacg acctggtttg ttaccaagag
     7261 tgatgaggtt gctcaattca ggggttgcaa gtgctaggaa gtaaaggaca aatacgatgg
     7321 ttacaccaag gaagataaaa cctttggctt tttgtttatt gtaaatctgt cctaacccag
     7381 gaatgataga cagcagggct gctttactag gttgttgctt ttccatatta actcctttca
     7441 taggatacta cttttttata agaaagctaa attatttgtg tctctattga taaattcaaa
     7501 gggggatttg atttccaccc cccttgaaca aattttttat tcaccaaatt tttgtttgat
     7561 tgtttctttg atcaatgtta cagcatcgtt agcagctgtt ttagcatctt tttgaccact
     7621 tacagcatca aagagcatat ttttcgctgg atcccaaact gcagacattt gagagatgtt
     7681 tggcagtggt tgagtgttct tgaactgttt gataacagct gttgtcaact catcgttttt
     7741 accttcagcg tatgaacgag cctcagtatt agctgggatt tcgttagtct tatcatataa
     7801 tactttttgt tgttcagttg caacaaggaa gtctacaaat ttttgagaag cttcaaggtt
     7861 cttaacggct tgaggaatga cccaagcttt accaccaccg aatgcagcat attcttttcc
     7921 atttggaaga gttgggatag ttgcaactcc gtagtttact ttagcatctt taaaggcttg
     7981 agctttccaa ggtccgtcga tgatagcagc tgttttacct tcttggaatt gagtttggat
     8041 taagtttcca gcaccttctg tatcttgcat acctttaggc catttttcgt accaagattt
     8101 agcgtaattg atacctacga tagaaccgtc gtttgcaaga ccgatgtctt tagcgtcttt
     8161 accgttttgg ccaaagacgt aagcaccgtt accggcaaga agtccatatg tatagtagaa
     8221 gtttgtccag tcagctagga aggcagtagt tttaccatct tcaccagcga atgcgtattt
     8281 gctatcttta gcaaggtttt ccaagtcagc aaatgttttt ggagcatctt tcaccaagtc
     8341 tttgttgtag tacataacaa gtgactcgat aacggcagga gcaccgtaaa ctttaccatt
     8401 agcagctgtt acaagagatt tagttgtgtc gtctgtttta gcaccatcgc tcaatttcac
     8461 ttctgaaagt tgtccgtcag aaccaaggct acctacacgg tcgtatggag ccatcataac
     8521 atcagggaca ttaccagatt ggttgtcaag agaaagttta tcaagacctc ctagagcatc
     8581 accagtttta agagtgactt ttactccagc ttctttttca taagctttag caacctcttc
     8641 aatatagctc ttatatccct cgtctacata tacagtgagt tctttgactt cagatgaacc
     8701 agaatcagca ggcttatcag cagttttgct tccgcaagct accaaaagca agctagcaag
     8761 tgtagcagtt ccaagcaccg cagtgctctt cataaattta gatgacatag tgtattcctc
     8821 ctaaagaata gcaagtttta ttgataagga aacgcaaacg ttttccttta tgagcttagt
     8881 atagcacaaa tagaaaacgg ttgcaagtat tttttgtaaa aattttaaaa aatttttaag
     8941 cttgatttga tagcataatt ttgcatttta atagaagaaa agtatgaaat agataagaat
     9001 acagtatttt taataaaaat atatggaatc tgtctaaaga gggaaatcag gaggggctac
     9061 ctccctgttt ctaatctata tctattttct atagacgttt gtgctttgtt acatataaat
     9121 tcaagctccc taaggaggtt ttatactttg tagactgtct cgtgagagtc aaaccttagg
     9181 attagatagt tttaagttat ctttgctaaa atgagttagt ttccttaaaa ataatcaaaa
     9241 aagtttttta aaaacgcttg caattatgct tgaaaaggag tatacttata agtaacgcaa
     9301 acgtttgcgt ctgcaaaata cgcaacgttc cattatttta acacacgagg tgctattatg
     9361 aaaaaacgtc aaagtggtgt gttgatgcac atctcttctc ttccaggagc ttacggaatc
     9421 ggatcatttg gtcaaagtgc ttacgacttc gttgatttct tggtccgtac aaaacaacgt
     9481 tactggcaaa tccttccatt aggagcaact agttacgggg attctcctta ccaatctttc
     9541 tcagccttcg caggaaacac tcattttatc gatttagata tcttggtgga gcaaggtttg
     9601 ttggaagcaa gtgaccttga aggagttgac tttggtagcg atgcgtctga agttgactat
     9661 gctaaaatct actatgcacg tcgtcctctt ttagaaaaag cggtgaaacg tttctttgaa
     9721 gtcggagatg ttaaagattt tgagaaattt gctcaagaca accaatcatg gcttgagctc
     9781 tttgctgagt atatggctat caaagagtat tttgacaatc ttgcttggac tgaatggcca
     9841 gatgcagatg ctcgtgctcg taaagcttca gcacttgaaa gctatcgtga gcaattggca
     9901 gacaagttgg tttaccaccg tgtgactcaa tacttcttct tccaacaatg gttgaaattg
     9961 aaagcttacg ctaacgacaa ccacatcgaa atcgttgggg acatgccaat ctacgtagcg
    10021 gaagattcaa gtgatatgtg ggcaaatcca catctcttca aaacagatgt caatggtaag
    10081 gctacttgta tcgcaggatg cccaccagat gagttttctg taactggtca gctttggggt
    10141 aacccaatct atgactggga agcaatggac aaagacggct acaaatggtg gattgaacgc
    10201 ttgcgtgaaa gcttcaaaat ctacgatatc gttcgtatcg accacttccg tggcttcgaa
    10261 tcttactggg aaatccctgc tggttccgat acagcagcac ctggtgagtg ggtgaaaggt
    10321 ccaggctaca agctttttgc agccgttaag gaagaacttg gtgagctaaa catcatcgca
    10381 gaagaccttg gcttcatgac agatgaagtg atcgaattgc gtgaacgtac tggcttccca
    10441 ggaatgaaga ttcttcaatt tgccttcaac ccagaagacg aaagcattga tagcccacac
    10501 ttggcacctg ctaactcagt tatgtacaca ggaacacacg ataacaatac ggttcttggt
    10561 tggtaccgta atgagattga tgatgcgact cgtgagtaca tggctcgtta cacgaaccgt
    10621 aaagaatacg aaacagtggt acacgctatg cttcgtacag tattttcatc agttagcttt
    10681 atggcaattg caactatgca agatttacta gaattggatg aggcagctcg tatgaacttc
    10741 ccatctaccc ttggtggaaa ctggtcttgg cgtatgactg aagatcaatt gacaccagct
    10801 gtcgaggaag gtttgcttga cttgacaaca atttatcgcc gaattaatga aaatttggta
    10861 gatttaaaga aataagacaa taatcaggag acaactaaac atgttatcac tacaagaatt
    10921 tgtacaaaat cgttacaata aaaccattgc agaatgtagc aatgaagagc tttaccttgc
    10981 tcttcttaac tacagcaagc ttgcaagcag ccaaaaacca gtcaacactg gtaagaaaaa
    11041 agtttactac atctcagctg agttcttgat tggtaaactc ttgtcaaaca acttgattaa
    11101 ccttggtctt tacgacgatg ttaaaaaaga acttgcagct gcaggtaaag acttgatcga
    11161 agttgaagaa gttgaattgg aaccatctct tggtaatggt ggtttgggac gtttggctgc
    11221 ctgctttatc gactcaattg ctactcttgg tttgaatggt gacggtgttg gtcttaacta
    11281 ccactttggt cttttccaac aagttcttaa aaacaaccaa caagaaacaa ttccaaatgc
    11341 atggttgaca gagcaaaact ggttggttcg ctcaagccgt agctaccaag taccatttgc
    11401 agactttact ttgacatcaa ctctttacga tattgatgtt actggttatg aaacagcgac
    11461 taaaaaccgc ttgcgtttgt ttgacttgga ttcagttgat tcttctatta ttaaagatgg
    11521 tatcaacttt gacaagacag atatcgctcg caacttaact ctcttccttt acccagatga
    11581 tagtgaccgt caaggtgaat tgctccgtat cttccaacaa tacttcatgg tttcaaacgg
    11641 tgcgcaattg atcatcgacg aagcaatcga aaaaggaagc aacttgcatg accttgctga
    11701 ctacgcagtt gtccaaatca acgatactca cccatcaatg gtgattcctg aattgattcg
    11761 tcttttgact gcacgtggta tcgatcttga cgaagcaatc tcaattgttc gtagcatgac
    11821 tgcctacact aaccacacaa tccttgctga agcgcttgaa aaatggcctc ttgaattctt
    11881 gcaagaagtg gttcctcact tggtaccaat catcgaagaa ttggaccgtc gtgtgaaggc
    11941 agagtacaaa gatccagctg ttcaaatcat cgatgagagc ggacgtgttc acatggctca
    12001 catggatatc cactacggat acagtgttaa cggggttgca gcactccata ctgaaatctt
    12061 gaaaaattct gagttgaaag ccttctacga cctttaccca gaaaagttca acaacaaaac
    12121 aaacggtatc actttccgtc gttggcttat gcatgctaac ccaagattgt ctcactactt
    12181 ggatgagatt cttggagatg gttggcacca tgaagcagat gagcttgaaa aactgttgtc
    12241 ttatgaagac aaagcagctg tcaaagaaaa attggaaagc atcaaggctc acaacaaacg
    12301 taaattggct cgtcacttga aagaacacca aggtgtggaa atcaatccaa attctatctt
    12361 tgatatccaa atcaaacgtc ttcacgagta caaacgccaa caaatgaacg ctttgtacgt
    12421 gatccacaaa taccttgaca tcaaagctgg taacatccct gctcgtccaa tcacaatctt
    12481 ctttggtggt aaagcagctc cagcctacac aatcgctcaa gatatcattc acttgatcct
    12541 ttgcatgtca gaagttattg ctaacgatcc agcagtagct ccacacttgc aagtagttat
    12601 ggttgaaaac tacaacgtta ctgcagcaag cttccttatc ccagcatgtg atatctcaga
    12661 acaaatctca cttgcttcta aagaagcttc aggtactggt aacatgaaat tcatgttgaa
    12721 cggagctttg acacttggta ctatggacgg tgctaacgtg gaaatcgctg agttggttgg
    12781 agaagaaaac atctacatct tcggtgaaga ttcagaaact gttatcgacc tttacgcaaa
    12841 agcagcttac aaatcaagcg aattctacgc tcgtgaagct atcaaaccat tggttgactt
    12901 catcgttagt gatgcagttc ttgcagctgg aaacaaagag cgcttggaac gtctttacaa
    12961 tgaattgatc aacaaagact ggttcatgac tcttcttgac ttggaagact acatcaaagt
    13021 caaagagcaa atgcttgctg actacgaaga ccgtgacgca tggttggata aagtcatcgt
    13081 taacatttct aaagcaggat tcttctcatc tgaccgtaca atcgctcagt ataacgaaga
    13141 catctggcac ttgaactaat actcttcgaa aatctcttca aaccacgtca gctttatctg
    13201 caacctcaaa gcggtgcttt gagcaacctg cggttagctt cctagtttac tctttgattt
    13261 tcattgagta taagatacaa atttatacta atacatcttg taaaaaagcg agtttcgatt
    13321 gaaattcgct tttttaatga tgtagatttg ggtcaatctt gtctaaaaat agggaaatcc
    13381 tagatacagt gaaggcttta aatgctggtt tttactgtcc tcagccttat attttttcgt
    13441 agttgattac ctcatacctc ttgtattcgc ttacataaag tattataata taattgtagg
    13501 aaagaaggtg tttttatgat atacacactt aaattggtgt tgtttattac ctttcttgta
    13561 ataagcttgt tacctgataa gatttttgga aaaaataaaa aaatttggaa aatagttttt
    13621 gcaatattga cggcagtggc agcattgtca tttatgtact aagttatttt aagaatgtag
    13681 ggaaataaac cctacattct ttttagtttt ttctgttttc taaattctat ttatccaagc
    13741 gcttcaacat ttcttgcttc ttcgcttcaa gttctgcacg cttttcttcg atttcggcat
    13801 gttttttctc gagttcagaa caacttgcac cattgctaaa ttcttttcgc catcaggaga
    13861 tagggtgagt cgacatgtct attactcacc caaagcagtc ctacaaagca ggaattttct
    13921 gttacttttt tggaaatagt aacgtttata cagctttgac acttcgtatc aaagcgccaa
    13981 acacactccg agggatttac agaaagcaga aaaggaatga tctggtataa gatcattcct
    14041 tttctctctt tttctttaag taattatata caatgtacga cgaagtcgtc attgcaatgc
    14101 tgatccacca cctaaaggaa actttaaaca acattgataa gataaagaat ataaacaacg
    14161 aaaatacgtt atacccaatt aattttattg tatatctcat gattaaaagt taatccttcc
    14221 gttgttagga atggcatcat ttttatccca taattgtgct aaataagtcc ccggtgataa
    14281 taaatttata gcaaattcta aagcaacatc atttacaaac caactaccta gatatctaga
    14341 aattgctgaa cgaatagcac tttttgctgc atgttttcct tttactttaa ttagatttgc
    14401 aaggcctgca gtagttcctc ctaatgctaa agctattgca gtatctaata gagcacccat
    14461 ttgattaact gtaatacctt gccaagctgc tctaaatgga gagtatgtag gtgggattgt
    14521 ataatcgcct tgtaattgtc ggttaattac ttctttgatc cattgttgtg agacgtctgg
    14581 atgaaaagat tggatttcgt ttgcaagtgt attgatttgt tcttctgtta gagaagtgac
    14641 aggttgaagt tccatatttg tttcaatttg tgatacttgt tcagaagcgt atacagctga
    14701 aacacttgga atcgctgata caattaacac aattgacgtc aaaaaaaccg aaataaattt
    14761 cattaatttg ttcatgagct tttctccttt ttatttgtat ctgcttacat tttatcatat
    14821 gctgttatta tagtcaaaaa aatatgctat tatgttaaaa aaatattttt caaaatataa
    14881 atggacggat ttattttgga ttttatttgt tattttgacc tgcctctata ttggtaacca
    14941 tgatttgttt actctcaatc atcaagaatt ctcttttcgt ggtagcgttt ggggtctggt
    15001 actggcctta tatcacttac tattcattga taagtttgtt atatcgaatc gaaaataaag
    15061 attagagcta tgcttgactg tgtactttta ggattgattt tggaggaaga ttttgtctct
    15121 attatttatt attttaaatt tatttatttt gtataagatc tattctttga ggcgggaaaa
    15181 atcgaaatac ttgatttata cggcctatat catatttggg gtaaatgtag tatatggtat
    15241 tcaatggtta ttaagagaac tgatttcaac tatttcccct taatgtgtat ggaaactata
    15301 acaaaacgca taagattaag gtttgtgtac ctgttcttat gcgtttttat aatattgaag
    15361 attttcggta agttttatac ctttgggaag tctagtttag aatgctttcc caaccaaaat
    15421 ctctgcttcg atggtaatct ctgtcagttg gctccagtca atcttgctct ggtcaacgtg
    15481 aaagaggaga ggagtcatac tgagtagggc ttggagttgt tctgctgtga tagtcttagt
    15541 cagagaggca gtttgactag ataggatggt aaagtgttcc tggaaatgct ccttgatatc
    15601 ttggttagaa tactccttgt ttgtcagctg gtcctgtact ctttgacgga tttctttgag
    15661 gtgattttca gttgggataa cctttatcaa gataccgtct ttggataaaa cgcgacgaaa
    15721 ttctccatag ttggcaggtg agaagatatc aagcagaata tccatgttag cgtcttttat
    15781 aggaagtcgt gccaagtcgc caacgaacca attgactgcc cagttgggtt cacttttagc
    15841 agcgatttgg actgaatctt tggagatgtc aaaggcatag aaagtttttt cagagtgact
    15901 ttcttgtagt ttgcgagaat agaatccttc accacaaccg atatccaaaa ttgttgtggt
    15961 agtttttgag cttgcaagca agtcagatac agcatctaag atagcttggt aaaagccggc
    16021 ttctaggatt tgttgacggt tttgaaaatt ttccttgtca tagttagcag attgcttgat
    16081 ttgaggtgct agattgacat agccaaattt cgccaagtca aaagaatgac ggttgcagca
    16141 cttgaaatta gtctctaaca gagtcagatt ttcttgacag ataggacagg caaaggcagt
    16201 cgcagaagca aaacgctgaa gtttgggctt gagatttgta ttcatagttt aagtgtatca
    16261 aaagaggcaa atgaaagcaa ctttaggaat aagtagattc agtagaaata aaactaattc
    16321 tccaatttat agaatgaaat tgcttttata tctaaattgc tatataataa tgataaggag
    16381 gaaataagta tgttaaaaga agtattaacc gttgcaaaag ttgcgaaaaa atcttcatta
    16441 tttttgggtg gtgtcgcatt tggtaccctt ggtttgaaaa tcttagcaag taaggaagct
    16501 aaaaaaggtt attctaaagc tttggctaag gcttacaagt tgaaagacga gctagatgca
    16561 tctgtttctg ttgtgaagca acatggagac gatgtcttgc aagatgccaa atatttgtac
    16621 gagcaagaga aaaaagaaga gcaattagat agccttatag gtgaataata tgtcttttaa
    16681 agtgctacat agaggatacc aacatatccg actatcatct tctttttcac ttaccttgga
    16741 tattcaagac tatcttcgtt ccttggcgag agatgaaaag gggattgagt ctatccagtt
    16801 ttacatggat caacagcact ttactctacg cataaaagaa ggcttttctg tattagataa
    16861 tgcagaagcc tttttaaaaa gaattgataa agggaaagtt tctgagttga tgactcttcc
    16921 cattcgtaga gaagagagtg cttattctat tgtttcaggt gcagcggtta agcgtgtact
    16981 ttttcgtagt tttgtgccgt atcctattcg ctatatatgg acttgttatc aggctttggg
    17041 ttatattaga gaagcctatc aaacactagc gcgtaaggaa ctaacgatgg aagtcttgga
    17101 ctgttcggct attttattgt ccttgtttat gaaccaatcc aagacagcta gcaatatcat
    17161 gtttatgctt gatttgggga atcatttaga tcagtggtcc ttgaaaaaaa ctgcaacaga
    17221 tttagaacag agtcttcttg caaaagagag cgatgtattc ctagtacagg gcgatacggt
    17281 tgttagtatc aagagttccg atgttcaaat aggagatgtc ttgatcttat ctcaaggaaa
    17341 tgaaattctg tttgatggac aagtagtttc aggtttaggt atggtcaacg aaagttcctt
    17401 gacaggagag agttttccag ttgaaaaaag agagtctgat ttggtttgtg caaatacagt
    17461 attagaaact ggagagttac gcattcgtgt aacagataat cagatgaaca gccgtatttt
    17521 acagctgatt gagttgatga agaaatctga agaaaacaag aaaacgaaac aacgctattt
    17581 catcaagatg gcggataaag tcgtcaaata taatttcttg ggggctgggc tgacttacct
    17641 attgacaggt tctttttcta aggctatttc tttcctattg gtcgatttct cctgcgcttt
    17701 gaaaatctct actcctgtag cttatttgac agttatcaag gaagggttga accgtgaaat
    17761 ggtgattaag gatggagatg ttctggagaa atatctggaa gttgatactt tcttgtttga
    17821 taagacagga acaatcacaa ctagttatcc tatagttgaa aaggtgttac cttttggaga
    17881 ctatagtgag gaagatattc tcagaatcag tgcctgtctt gaggaacaca tttatcatcc
    17941 tattgctaat gccatcgtca agcaagctga gatagaggga attgaacatg aggaaatgca
    18001 tgggaaactc caatatatcg caagcaaggg gatcaaatct catatagatg gccaaccagt
    18061 tcttattggg aattatgtct tgatgcagga tgagcagatt catatcagtt cagaacaaaa
    18121 tgctttaatt gaagagtaca agagtcacta caatctctta ttcttggctt atcaaaatga
    18181 attgattgga atgttctgca ttcatactcc tttgagaaaa gaagcaaaaa cagccttgga
    18241 taaacttaag gcacagggga aaaaattgat tctggcaaca ggagacacct tgattaggac
    18301 agaggaatta gtcaaagatt tgccctttga tcaggtctat acagacttga aacctgatgg
    18361 gaaatttgag ttagtagaga aactgcagaa agcaggtcac actattttga tggttggaga
    18421 tggattgaat gactcagcgg ctttaactct atcagatatc ggtgtggtga tgaatgagag
    18481 tgcagatatt tctaagcaga tgagtgatat cttattgtta gataatcgtt tggatttctt
    18541 ccaagagttg gattcgttat catcatcttt gcaaacactc atcaagaaaa atattcagga
    18601 taccgttgtc gtaaatagta gtttgattgg ctttggctta tttaattggt tcagtccttc
    18661 aaatctctct atcttacata atctaacaac cttgcgcatt gtcctgcgta gcctgtctat
    18721 taaaaataga tagatgagag ttattaacag caaaaaggag ttacctttct cgaggttaac
    18781 tcctttgttt atagataaat gttgaatagt ttagtaagtc aatacaaagt attttttctt
    18841 cccacgacgg ataacagtca gttcattttc taacttatca gcgtcactca agacatagtc
    18901 aaggtcttgg atgcggtcgc cgtttacgta gatggctccg ttttggacgt cttcacgggc
    18961 ttggcgtttt gagttaacta taccagatga gacgagcagt tccacgatat tgttgttttc
    19021 gtctgcctgt acttggtagt ttggcacacc acgaagtcct tgtttgagct ctttgacaga
    19081 aaggtttttg atgtttcctg caaagagttg ctcagtgatg ttaagtgctt ctttgtaggc
    19141 ttcttctccg tgaacaagtg taacaacttc acgagccaag actttttgag ccaagcgttc
    19201 gtgtggcgct gcttcaaatt gtttacgaat atcttcaatc tcatcaagtg acaagaaagt
    19261 aaagattttc aagaagcgaa cagcgtcagc gtccatcacg ttcatccaga attggtacat
    19321 ttcgtatgga gaagtctttt cgggattgag ccagacggca tttccttctg atttaccaaa
    19381 ttttttacca gttgcatctg tgattagtgg aacagtgata acgtgaccag tcttgtccgc
    19441 cttacgacga agcaattcgg taccagctgt catatttccc cactggtcag aaccaccgat
    19501 ttgaagagtg acattatggt cttggttaag gacgaagaag tcgtaccctt gcatgatttg
    19561 gtaagcgaac tcagtgtaag aaattcctgt ttcgatccgt tttttaacag attccttact
    19621 catcatgtag ttgaccgtga agtactttcc aatgtcacgg aggaagtcaa tgaagctgat
    19681 gctgccaaac cagtcgtagt tgttgaccat gacagccttg ttttcgccat tttcaaagtc
    19741 aagaaaacga gaaagttgtc cttggataga cttgacccag ccatctactg tgtcttttgt
    19801 ttggagacta cgttcagcat ctttgaagga cggatctccg atgagacctg tagcaccgcc
    19861 aacgagcgca taaggtttgt gacctgctag ttgcaagcga cgacttgtca agattgcgac
    19921 aaggtggcct aggtgaaggc tgtcagcagt tggatcgtag ccagtataat aagaaacttg
    19981 accttcttct agggctttac gcaaagcttc ttcatcagtc gtttgaaata tcaaaccacg
    20041 ctcttttagc tcatcaaaaa tgtgcatgtg tcttttctcc tttttaaaat tattgtttct
    20101 acctattgta tcacaaactt gggcaatagc ctagcagaat agggaagaaa gtggctattt
    20161 tattgaaaat ttcccttttg tggtataata gataaagtga ggaaatccat gcaaaatcaa
    20221 ttaaatgaat taaaacgaaa aatgctggaa tttttccagc aaaaacaaaa aaataaaaaa
    20281 tcagctagac ctggcaagaa aggttcaagt accaaaaaat ctaaaacctt agataagtca
    20341 gccattttcc cagctatttt actgagtata aaagccttat ttaacttact ctttgtactc
    20401 ggttttctag gaggaatgtt gggagttggg attgctttgg ggtacggagt ggccttattt
    20461 gacaaggttc gggtgcctca gacagaagaa ttggtgaatc aggtcaagga catctcttct
    20521 atttcagaga ttacctattc ggacgggacg gtgattgctt ccatagagag tgatttgttg
    20581 cgcacttcta tctcatctga gcaaatttcg gaaaatctga agaaggctat cattgcgaca
    20641 gaagatgaac actttaaaga acataagggt gtagtaccca aggcggtgat tcgtgcgacc
    20701 ttggggaaat ttgtaggttt gggttcctct agtgggggtt caaccttgac ccagcaacta
    20761 attaaacagc aggttgttgg ggatgcgccg accttggctc gtaaggcggc agagattgtg
    20821 gatgctcttg ccttggaacg cgccatgaat aaagatgaga ttttaacgac ctatctcaat
    20881 gtggctccct ttggccgaaa taataaggga cagaatattg caggggctcg gcaagcagct
    20941 gagggaattt tcggtgtaga tgccagtcag ttgactgttc ctcaagcagc atttttagca
    21001 ggacttccac agagtcccat tacttactct ccttatgaaa atactgggga gttgaagagt
    21061 gatgaagacc tagaaattgg cttaagacgg gctaaggcag ttctttacag tatgtatcgt
    21121 acaggtgcat taagcaaaga cgagtattct cagtacaagg attatgacct taaacaggac
    21181 tttttaccat cgggcacggt tacaggaatt tcacgagact atttatactt tacaactttg
    21241 gcagaagctc aagaacgtat gtatgactat ctagctcaga gagacaatgt ctccgctaag
    21301 gagttgaaaa atgaggcaac tcagaagttt tatcgagatt tggcagccaa ggaaattgaa
    21361 aatggtggtt ataagattac tactaccata gatcagaaaa ttcattctgc catgcaaagt
    21421 gcggttgctg attatggcta tcttttagac gatggaacag gtcgtgtaga agtagggaat
    21481 gtcttgatgg ataaccaaac aggtgctatt ctaggctttg taggtggtcg taattatcaa
    21541 gaaaatcaaa ataatcatgc ctttgataca aaacgttcgc cagcttctac taccaagccc
    21601 ttgctggcct acggtattgc tattgaccag ggcttgatgg gaagtgaaac gattctatct
    21661 aactatccaa caaactttgc taatggcaat ccgattatgt atgctaatag caagggaaca
    21721 ggaatgatga ccttgggaga agctctgaac tattcatgga atatccctgc ttactggacc
    21781 tatcgtatgc tccgtgaaaa gggtgttgat gtcaagggtt atatggaaaa gatgggttac
    21841 gagattcctg agtacggtat tgagagcttg ccaatgggtg gtggtattga agtcacagtt
    21901 gcccagcata ccaatggcta tcagacctta gctaataatg gagtttatca tcagaagcat
    21961 gtgatttcaa agattgaagc agcagatggt agagtggtgt atgagtatca ggataaaccg
    22021 gttcaagtct attcaaaagc tactgcgacg attatgcagg gattgctacg agaagttcta
    22081 tcctctcgtg tgacaacaac cttcaagtct aacctgactt ctttaaatcc tactctggct
    22141 aatgcagatt ggattgggaa gactggtaca accaaccaag acgaaaatat gtggctcatg
    22201 ctttcgacac ctagattaac cctaggtggc tggattgggc atgatgataa tcattcattg
    22261 tcacgtagag caggttattc taataactct aattacatgg ctcatctggt aaatgcgatt
    22321 cagcaagctt ccccaagcat ttgggggaac gagcgctttg ctttagatcc tagtgtagtg
    22381 aaatcggaag tcttgaaatc aacaggtcaa aaaccaggga aggtttctgt tgaaggaaaa
    22441 gaggtagagg tcacaggttc gactgttacc agctattggg ctaataagtc aggagcgcca
    22501 gcgacaagtt atcgctttgc tattggcgga agtgatgcgg attatcagaa tgcttggtct
    22561 agtattgtgg ggagtctacc aactccatcc agctccagca gttcaagtag tagttctagc
    22621 gatagcagta actcaagtac tacacgacct tcttcttcaa gggcgagacg ataattctct
    22681 aaatgaagtg gccaatcaat ggattgccac ttttttcctt tcgtgttaca ataagggtat
    22741 gaatcagtat cagaaaaaga ttgttaacgg aaaaatttat tcgctcctat ccggcttaat
    22801 atggggaatc tgtggaattt taggagagta cttctttact cattatcagg tgtcttcggg
    22861 ctggattacc tctatgcgtt tgacactggc agggagtctt gtactcattt ggtctgcaat
    22921 acaattaaaa tcgcaagtgc tagatatttg gcgagacaag aaaaattacc tgcccttttt
    22981 agcctatgct attttgggga ttttttcagt tcagtatttt ttctatctct gtttagaata
    23041 ctcaaatgct acgacagcaa ctattttaca gtttattagc cctgtcttta tcctctttta
    23101 caatcgcttg gtttatcaaa aacgagcgtc aaaaagcgct gttttctatg ttttggttgc
    23161 catgctgggt gtttgcttga tggcgacaaa gggagatctc tctcagttat ccatgacgcc
    23221 gctagctctt ataacaggtt tgctgagtgc catgggtgtt atgtttaatg ttatcttgcc
    23281 ccaacctttt gctaagcgtt atggttttgt tcctacggtt gggtggggga tgattttggc
    23341 aggtttgttt agcaatgtcc tctcgccggt ttatcagctt tcctttactc ttgatatttg
    23401 gagtatcttg atttgcctca ttatcgcttt ctttggaacg gcttttgctt ttttcatttc
    23461 catgaaggct gtgtccttgg tttctccttt ggtggtttcc gttatcagtg ccagtgaacc
    23521 tctctcttct gctctcttga gtgttttgtt cttaggatta gtagtggatt ggtccctcct
    23581 tctagctata gccttgatta ttttacccat gatatttttg tctatagaag aagcgaaaga
    23641 aagtagataa aaagtctttt cttaattcta aaagtgtgct atactagaat agtcaataaa
    23701 acacggggag atagttgtga agagtatttt taggttgtat cggtaggggc ttgcttttac
    23761 cgacagcacg ttttatctca catccctaaa aaatcatacc taaaaacaga caaaaaggtt
    23821 tcaaatttga ggcctttttt ggtagaatag gtatcattat aacgaaccag gaggcaccta
    23881 tgactgctac aaaaatgaac gctcaagaaa ttatccaatt tatcgccaat gctgaaaaga
    23941 aaaccagtgt caaagtaacc tttgaggggc aactcgcaac tgctgtgcct agctctgttg
    24001 tcaaactagg aaatgtccta ttcggagact ggaaggacgt ggctccgctt cttgaaggtt
    24061 tggtagaaaa tcaagattat gttgtcgagc aagatgctcg taattctgca gttcctttgc
    24121 tagataagcg tgctatcaac gctcgtatcg agccaggtgc tattatccgt gaccaggtgg
    24181 aaattggtga caatgctgtt atcatgatgg gagctgttat caatatcggt gctgaaatcg
    24241 gtgctggaac catgattgac atgggtgcca tccttggtgg ccgtgctatc gttggaaaaa
    24301 atagccacgt tggtgcaggt gcagttttgg caggtgtgat tgagccagct agtgctgaac
    24361 cagtctgtgt cggagacaat gttcttatcg gggctaatgc agtggttatc gaaggagtcc
    24421 aaatcggtag tggttcagtt gtcgctgcag gagctatcgt tacccaagat gtcccagaaa
    24481 acgtggtagt agcaggtgtt ccagctcgta ttatcaaaga aattgatgcc caaactcaac
    24541 aaaaaacagc gctagaggat gcgcttcgta ccttgtaatt gtaaaagtaa aaaagaggcg
    24601 gaaccctttt tccagcctct ttctgctata tcggaggaca gatagatgtt agatttgatt
    24661 cagactagac gagctttaca ccagattcca gagattggct tggaggagtt caagactcag
    24721 gcttatttgc tggatgtgat tgagaaattg actacgggca aggattttgt tcaaattcgt
    24781 acttggcgga cagggatttt ggtctacctg cagggaagtc agccggagcg aaccattggt
    24841 tggcggacag atattgatgg cctgcctatc gtcgaacaaa caggtctacc ttttacttct
    24901 caacaccaag gtcgcatgca tgcctgtggt catgattttc atatgaccat tgccttaggc
    24961 tgtcttgagc gcgcccttga ggagcaaccc aagaataatc tgctctttct atttcagcct
    25021 gctgaagaaa atgaagctgg tggtatgctc atgtatgagg acggtgcttt tggagattgg
    25081 ttgccaaacc aattctatgg tctccatgtt cgtccagatt tgaaagtcgg ccagattgcg
    25141 actaatactc atacactctt tgcaggaact tgcgaggtga agatccgttt caaaggtaaa
    25201 ggtggccacg cagcttttcc tcatgaagcc aatgacgcct tggtggcggc tagttacttt
    25261 gtgacccaag tgcagtcagt tgttagccgc aatgtcaacc caatcgaggg agcagtggtg
    25321 accttcggcg tttttcaagc tggaaccacc aacaatgtca tcacagacac agctttttta
    25381 catggaacta ttcgtgcctt gacacaggac atgagtctct tggtgcaaaa gagggtaaaa
    25441 acagttgcag aaggggttgc agctgccttt gatatggaag tcgaagtgga actcaaacaa
    25501 ggtggatacc tacctgttga gaacaatcca gccttggcgc gtgaactgat ggacttcttt
    25561 gacgagaaag acggaatcga gttgattgat atcgaacctg ctatgacagg cgaggacttt
    25621 ggttatctcc tttcaaaggt tgatggcgtg atgttttggc taggtatcga tagtccctac
    25681 gctcttcatc accctcaaat gagtcctaag gaagaagtct tagctattgg ggtggctgcg
    25741 gtgtctagtt tcctgaaaaa gaaggcagca gaatagaggg cttgtctatg aaatcggaat
    25801 tacgcaagca agtcttgcat gaaatgaagg ctatatctca agagcaaaaa caggctatag
    25861 accaagcttt aaccgagcga attttacaac acccctttta tcaagaagcc aaggtcatcg
    25921 caacctacct ctctttttct catgagtttc aaacgcggga actgattgag caggcgctga
    25981 aggacggcaa gaaggttttg acacctaaga cctatcccaa ggggcgcatg gattttgtgg
    26041 tctatgatcc gcaacagttg gtaaaaactt cctttgcctt actggagcca cagggagatt
    26101 tggaagtagt ggatgcatct cagattgatt tgattcatgt tcctggcctg gcttttacga
    26161 cggatggata tcggattgga tatggtggag gttattatga ccgctatctg gaacattttt
    26221 ctggtcgtgc tttgagtacg atatatcctt gtcaaattca ggactttata cctgaaaacc
    26281 atgatattcc tgttcaggag gtattaattg atgaaggaaa tctttgatag acgttaccct
    26341 gtgacgagtt tcttcctctt agtgacggcc ttggtatttt tactaatgtt ggtcactgca
    26401 ggcggaaact ttgacagggc agatacatta tttcgatttg gagccatgta tgggccagct
    26461 attcgcctct ttcccgagca ggtttggcgt ctcttgtctg ccatttttgt tcatattggg
    26521 tgggaacatt tcattgttaa tatgctttca ctttattatc ttggaaggca ggtagaggag
    26581 attttcggtt ctaagcagtt tttctttctc tatcttttat caggaatgat gggcaatctc
    26641 tttgtttttg tatttagtcc taaatcctta gcagcaggcg cctctacctc tctttatggg
    26701 ctatttgccg cgattattgt tcttcgctat gcaactcgca atccttatat tcaacagcta
    26761 gggcaatcct atctgacact ttttgtagtt aacattattg gaagtgttct gattccagga
    26821 atcagcctag caggccatat cggtggtgca gttggtggcg catttctagc agttatcttt
    26881 ccagttagag gagaaaaacg gatgtataat accagccaga gattaggagc ggtagtcttg
    26941 ttcgtaggac tcgccatttt gcttttctac aagggaatgg gaatgtgacg aagttgaaag
    27001 aaaatttgtg taatgaaaaa agataaggca ttttttgaac cttatctttt tattttattt
    27061 tattccttct cagtcaattc ttttccaagt tggatgaggt aattcttcaa atcatctttg
    27121 acttgtgggt gtttgagggc gtagtcgatg gatgttttca tgaagccaaa cttgtctccg
    27181 acatcgtaac gagccccatt gaactcacga gcaaatacac gttgtgtttt attgagggtg
    27241 tcgattgcat ctgtcagctg aatttcattt cctgcacctg gagcttggtt ttcgaggatt
    27301 tggaaaattt caggcgtgag gaggtagcgt ccgataatag caaggtcgct aggagcgtcc
    27361 tctggagctg gtttttcaac aaaggtttca acactgtaaa gaccatcttt tccttcgcct
    27421 tgcggagcaa taaccccgta agcagatact tcgtcatgag ggactggcat gacagcgata
    27481 gtagacgcgt gggtacgctc gtagtcatcc atgagttgtt tggtaagtgg aacagccttt
    27541 tcgtctgtga tatccatcaa gtcatcacca agcataacga caaaaggttc atttccgacg
    27601 aaagccttag cttgcaaaac agcatctccg agaccgcgtg gatgagtttg gcggataaaa
    27661 tgcagacgca tgtcagttgt tttatcaact agcttcaaaa gatctgtttt ccctttttct
    27721 ttgaggttat attccaattc gaagtttgaa tcaaagtggt cctcaataga acgttttgat
    27781 ttaccagtga caactagaat atcttcaata cctgatttga gagcctcttc cacgataaac
    27841 tggatagttg gtttgtctac gattggcaac atttctttgg caagggcctt ggttgctggt
    27901 aaaaatcgag ttcctagtcc agcagcaggg atgactgcct ttctaacttt tgatgtcata
    27961 aaaatccttt ctatagaggg ttaagaccac tcattttctg ctttaaattc attgttcatg
    28021 atgtcataaa tggcatcttt gatattggtt ccgtgataaa taacttggta aatagcctgt
    28081 gtaatgggca tatagactcc aagttcttgg gctagttcat aggctgctcg agtcgttgaa
    28141 attccttcga ttaccatgcc catattagct tctatatcag ctagggattc tcctcgtccg
    28201 agagcatctc cagctctcca gttacgagag tggatggaag ttcccgttac gatcaaatct
    28261 cccacaccag ataagccgct ataggtcaat ggactggccc cgagtgctac ccctaggcgg
    28321 gtgatttctg ctaaacctcg agcgatgatg gctgccttag cattatcacc aaatccaaga
    28381 ccatgtaaag ctccagcacc gacagcaata atatttttaa gagcaccagc agtttcaacc
    28441 ccgataacat ccgtattggt ataaagtcgg aagtagtgat tactaaatag ctcctgaacg
    28501 tattgagctg tttgtaaatc tttagaagca gcagtgatta aagttaggtc acgcacaatg
    28561 gtttcttccg catgactagg ccctgaaaca acgacaatat cactgcggag ctgttcagga
    28621 atttcttctt caaggatagt tgataatcgt ttatggctat caggttctaa tccctttgaa
    28681 gcgtgcatga tgatagcctt atggtccaag gtttgtgcaa cttgttgggc aacaagtcgt
    28741 gtcacttttg ttgggacaac aaacaaaatc gcatccacat ctttcaatgt ttctgctaag
    28801 tcggtgtagg caatgatatt ttcatctaga acgacatctt taaagtagtg cttgttagta
    28861 tgataggtat taatttcatt gatttgctcg ggaagatttc cccaaatacg tacctcgtgt
    28921 ccattgtcat ttaagacttg tgaaagggca gttccccaag aaccaggccc caagacggcg
    28981 acggtttgtt tttccatgat ttcctccttg atagagttct ttccattatt ctatcatatt
    29041 ctagaggatt ttgcacttgc attactgggg tatggtggaa aaatacacaa agaccgagat
    29101 gaagggataa actcttagtc tttagttaaa gtgagaagaa atctgataga tagtttgatt
    29161 cagtatatgc tataaataga ggtaaacaac tcaggaggtt cttgtaggtt gcgagagttt
    29221 ggcgaaaaaa ttaaaagatt acgtttggct aaaaaaatca gtcgttcaga attttgtggt
    29281 gatgagtctg aattaagtat ccgtcaatta attagaattg aaaatggaga atccagacca
    29341 acactaacaa agttaaaata tatcgctgaa cgtttggggg gggtgaagat tacaagttga
    29401 tgccaagtta tatagagttg gataaggaat acctagaatt gaagtatttc ttgatgagga
    29461 ctcctacata cgaagatgaa actatcgccc aaaagaaaga gagtgttttt gctaagattt
    29521 ttgaagagta ttatgatagg ctacctgagg aagaaagatt tatcatccca aattattcat
    29581 atctagcact agcgaactac acagttcaaa aattaccaga aaagctagtt gaaatactgt
    29641 ccttctggtg attttgctta atttctgatg ttcgagacat gattgaggag atttgtcttg
    29701 attttttcct aaaaaagggc agactcctcc cttggtttga tgctcgattt ttaaaataag
    29761 gtgacttatt ctgttaggca tgttttcccc tgccctctag ctctatatgg aacagggagt
    29821 atcagattta tctggcagat tgtatcaaat aaggcttgaa actgttttga ataggcgtat
    29881 agacttgaga atttgagaat atgtcgtcta gcagtagaga catattttcc ggcaatatga
    29941 aggaagagac gtcgaaaacg cttgatagtc aaggacttta cttcatcacc agctagctgc
    30001 tttaaaaaga ggtagagatt ataagccaga cagcccatca tcatacgtac ttcattctta
    30061 atcatggtcg aactatctgt cttatcccca aagaatcctg ctttcctttc tttgataaag
    30121 ttttcagcat tccctcgttc acgatagaat tgaaacagct cctcactatc tacactgctt
    30181 aaattgttca aatgaacttt tttacaacca taaaaaagag cacttaatcg tactcttctc
    30241 ttttaaggat tagttgaatt aattcaaatc cactagttct cctgtttcta ggtagactag
    30301 gcgttcacaa atgttagcaa tgtaatcagc gaagcgttcc agatgtccta tgatataaag
    30361 gtattgagtt ccattgggaa ttgaggtttc ttggtctttc ataagtccaa tgatttcctt
    30421 tgataaggca taataatatt ggtcaatctg ttcatctttt tgagcaatac taatagcttt
    30481 tgaggcttgg tgcaaaggaa aggcaaccaa taaatcggct agcatgctga gggataattt
    30541 acccatttgg tgtaactgtt cttcgtcagg ggctagttga ttttctttta gttgcaaaac
    30601 agctttggca atgcctgcca tatggtctcc catacgttca aggtctgaac aagaagacat
    30661 gatgctaatc acaaatcgaa ggtcagacac ttgtggctgt tgcaaggcca acaaacgggc
    30721 acaggtcaat tcgatagcgc tttgaccttg gttgatagca tgatccttat tgataattag
    30781 ctctgccatc tccttgtctt tggaggctaa ggccagtaag gcttttgaag ctgtttcaag
    30841 gacaagttgc cctagtccta aaaaggattg ttctaattca tgcaattcta agtcaaattg
    30901 atttctcata ggtttttcct tccttatccg aaccgtcctg aaatatagtc ttctgtgcgc
    30961 tgatcttttg gattggtaaa cacgtcaacg gtatctccaa attcgcaaat ttctcctgtt
    31021 aagaaaaaag cagttttatc tgaaatacgt gaagcttgtt gcatgttatg ggtaacaatg
    31081 ataatcgtat aatccttttt tagttgctga atgaggtctt caatttttaa agtggagata
    31141 gggtctaagg ctgaagtcgg ctcatccatt aacagaacat caggttctac tgctaaagct
    31201 cgcgcaatgc aaaggcgttg ctgctgaccg ccagataagg acatggcact ctttttaaga
    31261 tcatctttga cttcttccca aatggctgcc ccttttaaag atttctccac taaggcatct
    31321 aattgttttt tgtctcgaat accatgtgtc cttggaccat aagccacgtt atcatagata
    31381 gacatggcaa agggattagg ctgttgaaaa accatcccta cacgcttgcg tagctgatta
    31441 aggttgaatt tgctactata aatatcttgc tcatctaaga ggacttggcc ttcaatatgg
    31501 caagaaggaa ccaaatcgtt catccggtta agggttttta gaaaagttga tttgccacaa
    31561 ccagatgggc ctatcaaggc agtaatctgt ctttctggta attgaatcga aatatttttt
    31621 aaggcttgaa aatccccgta aaataagtct aggtgtctga ctgaaaatgt tcccatacta
    31681 ggaagctcct ttcacaagtt ttcgagataa taagcttgat agagtattta tcattaaaac
    31741 agtaataatc aaaatcacac cggtagcata ggcttcattg acatgtagcc cctcacttga
    31801 cagcatatac atatgcaggg ctagagaacg acctgaagac atgagactac ttggcgtatt
    31861 ggtagaggta cctaatgtat acatgagggc agctgtctca ccaacgatac ggccaatagc
    31921 tagtatcact ccagctaaaa tacctggcat ggcaactggt agaacaattc taaaaacagt
    31981 ccgtaactta cctgccccaa gtccataact tgcttgacgc atgctatcac taacagataa
    32041 aagggcttct tctgttgagc gaataatgac tggcaacacc atgatgactg aggttaagat
    32101 tcctgataac agagagtatt gaaaacctaa gaagactaca aagaagagca tgccaaacag
    32161 accaaaaaca atggaaggaa tcccagacaa ggtatctgag gccaatcgca tgattttaac
    32221 acaaagggaa tctttttttg tatattccac aagataaaaa ccagcaaaaa tccctatggg
    32281 caaggctaaa agaagagcac caaagaccag aataacggtg gaaataatcg ctggcataag
    32341 ggaaatgttc tcagaagtat aagtccaaga aaagagggat agacttagat gaggtaagcc
    32401 tttgatgagg ataaaaccaa tgattaaaaa gagagagcca aaggttaaag ctgaaaaaca
    32461 ataaacgaga agttttagca ggtatttact cataagatga ttttcctttc aagtaggcaa
    32521 agtaggcatt aatcaagaga ataaggaaaa agagaactgc tgaggttgca ataagggctt
    32581 ccctatgctg acctgatgcg taagccattt ccagaacaat attggttgtt aaggttctgg
    32641 ttcctgaaaa gagtccactt ggaataatcg gctggttgcc tgccaccaaa ataactgcca
    32701 tggtttcacc tactgcgcga ccgattccta aaataactgc tgataaaata ccagatctcg
    32761 cagctggcaa gatgacacta aaaatactcc gttcatgact agctcctaga gccaagctac
    32821 cagaataata cgttttggga actgttcgga tagcagattc tgacaaactg ataatggttg
    32881 gcaaaatcat tattcctaat agtaacgaag cggttaggac actcatgcca tttcctaaaa
    32941 aggttctaat ccaaggcacc aataattgta ggccgaaaaa accataaaca atagatggaa
    33001 tggccgccat caagttgata gctgatttta agaagccata gacgggcttt ggacaataat
    33061 aaaccataaa caccgatgtc aagatgcctg ttggcacccc aatcacaatc gctcctaagg
    33121 taattaataa ggaaccaacg atcattggta aaataccata gcttgccgga atgttcgttg
    33181 gcgaccaatc actgcctaat aaaaaacggg caaagccgta gttagccatg aaaggtaagc
    33241 cattactaaa aataaagaaa cagattagca aaatagctac aacagctact gttgcactca
    33301 tgaaaaaaat tgccctaaaa actgcttctt tgaaggcttg ttttgtcaca tcttgtcctt
    33361 tctagtgaag aaagtaaggg agatacgaca cctccctact tgccttcttt atcttattgt
    33421 acgatgaaac gtctgcatct ctttagagat ttatggagca aacattttat ttaatcttgt
    33481 cccaggtggt taatttgcca ctaaaaacgt ctgcaagttc agccatactg acttggcttg
    33541 ccttattgtc attattgacc acaacagcaa taccgtctaa agcaatagca tcatgggtga
    33601 gactcttacc ttcttcagga gttaattccc tagaaaccat accaatatca gcggttttct
    33661 ccttaacagc ggtaatacct gctgaagacc cattagaggt aatatcaatc gtaacttctg
    33721 gattttcttt tttataagct tctgctaatt tttccattaa agaagatact gaagtggaac
    33781 ctacaacaga caacttgcct gataagtgtt ggcttgtata ttctgtggtt tcggttttag
    33841 cttcaataaa tttattatct gtgaccactt gttgaccttg tttggagtgg ataaagctga
    33901 taaaatcttg acctagcttg gaaagattag aagaccaaac aatgttgaag ggacgttgaa
    33961 gagggtattc accatctaaa actgtgtctc gactagcctt gacaccatca atctctaaag
    34021 ccttgacaga tttcgttaaa gatcccaagg agatgtagcc gatagcatta gcattccctt
    34081 gaactgctga gagaacacct tctgtactat tttgaatcac agctgttttg gcagtgttgt
    34141 caattttttt atcaccgtct tttttgagaa tccctgtgat ttctgtgaag gcaccccgtg
    34201 ttccagagcc attttctcgt gaaatcacct caatcgttcc tgaagctgac tgtttggaag
    34261 cagctgactg attgccacag gcaacaagcc caaatcctga taagccaatg gctgcaagag
    34321 taagcatttt tttgaatttc ataataatca cctttatctc tatgtatttt tcttgtgtag
    34381 gcttactaca tttatagtct aacaagtctt tgtaaaggtt tatccctgat tcatgtaaag
    34441 attgtgtaaa gaatcaaaaa aagccacttt tgaaaaatgg ctgctcctaa aaatagcttt
    34501 aaaaattatt agtcctgtgc gaaagattgg ttaggaagaa aaatcgtgaa gcaactgcct
    34561 ctgccaagct gactcgtcac cgtgacttgg ccacctaata attgactgag ttctttgaca
    34621 atggcaaggc caagaccagt gccaccagtt tgtctgcttc gacctttatt aactcggtaa
    34681 aaacgttcaa aaatacgatc ctgctctaat tgactaatac caatccctgt atctgataca
    34741 gaaatcttaa tgccttcgtt caccttttgg gtcttgacct caatttttcc cccttgttca
    34801 gtgtaacgga tggcattgga taaaagattg agtaagattt gggaaagtaa ttgactatct
    34861 gatacgaggg tgacatcatc tggcacctgc acctttagct gtaaatcctt cttcttgagc
    34921 tgaggttgca agctttgagt caaatcctgt acaaattctg ccaaagaaag ggtcgtccat
    34981 tgtataggca tttgttgagc cttagataag gtaagaagat gctcaacaat atgctcaaga
    35041 cgcaagcttt ctttgtaaat aatgtctaga aagtcatcct tgagcgcttc ttcttcagct
    35101 gacatcccct taatggtttc agcaaagccc ttaatcgaag taactggtgt cctcaattca
    35161 tgggaggcat ttgagacaaa ggctaaattt aacttttcat aagttctaat cgttgttaaa
    35221 tcatatagca agacgagcac agcttccaca gattgggtgg ggctaaaaac gggaactgct
    35281 gtcacttcta aaatcaagtc accctcatga aacccactta cttcttgttt taaccttgtt
    35341 ttttgatcaa aggcttggtg aactaaattt cgaatatcca tccgtttgag gtcatcaagt
    35401 gaacttatgt cgccgtccac atcgggaaaa taatgaggca gagagcgact ggataataac
    35461 atctgacctt gagcggaaac taaaaacgtc cccatggtta ggtgcgacag aagaacctcc
    35521 attgtttcgg ctaggtcctt gtattgctga tcctgttggg agactttggt ttttagggca
    35581 gacacatact gagccaaaga ctttaagtct tcttgccctt tttctaaaaa gtattcacta
    35641 ctggtcaaga gaggttggtg caaggtctca aaagcaactt cccatttcca aaggcaaaag
    35701 agccagtagc caccttgtcc caaagaaagg gctagaagaa agagaccgat gcctttactg
    35761 atccaagtta atgccatccc tgcaatcaga atgaggctaa cacttagatt gactagccaa
    35821 aattgaaggt agcgtttcat ctataactcc ttgaacttat aaccataacc ccgaatggtt
    35881 cgaataaatt gaggggcttt aggattgtct tcaatttttt ccctcaactt accaatatga
    35941 acgtccacca aacgtgtttc ctgcccaaag tcataccccc agatacgttc caaaagacgc
    36001 tctctagtca gtgtcatgtt gggatgtttc ataagataga gcaagagttc aaattctttt
    36061 ggggtcaaac tcagtaactt attcgccttg tagacttcat gacgctcagg gtatactttc
    36121 aaggtcccaa atagccaaga atcgtcagcg atattatctg aatcatctcc ttcttgttct
    36181 cctttagttc gcctgaggac agccttgaca cgcgccagca attctctagg gctaaaaggc
    36241 ttggtcaggt agtcatcagc ccctaattcc aaggccaaaa ccttatcaaa ttcatcactt
    36301 ttcgcagaaa ccatcataat tggagttttg acgcctttgg ctctcagccg cttacaaact
    36361 tccatgccat ctaattgtgg taacatgata tcaagcaaga taaaatcaaa gggttctgtt
    36421 tctgccaaag ctaaggcctt ccgtccattt gttaccaatt gagtagaaaa gccttcctta
    36481 cttaaatggt agtcaagcaa tttcagaatg tgttcttcat catccactaa taagacttgt
    36541 tttgtcatct attatctcct attggtaaca ttataacaca attatcagaa atcctaacat
    36601 tgctaaatca gattaaattt gcttatcaag actagtatct ggtcaaacgc tcaatcatct
    36661 ccttgtgctc tggataggtc gccagtagat ctaccctttc aaataattca aaatcctcaa
    36721 attcaaaacc aggagcaaca agacaagaaa ccagagcata atccttatca actgttgatc
    36781 cccaaatagt gcccttagga acacagtagt gaagttgttg ccctttggat atgtccaggc
    36841 ctaaagtgac tgcttcgtag tgaccatctg ctgtaatcat gtgaacagta agtggggatc
    36901 ctgcatgaaa ataccagatt tcatctgctg tcaatcggtg aaaatgtgaa ggattcgttt
    36961 cttctaataa gaaataaata ctggtataaa gcgcccttcc cttaccagca aggtttatag
    37021 tgtctgaagc tttttttgtt tgtctaaaat agccaccttc aacatgggga gctaactcta
    37081 gagttcttat caagtcttct ttatccgtcg gagccaatgg gttgaagtaa ctcttgttca
    37141 aaggtggtgt tacgatttca agaactcctc tcagctctga ggacacgata atgattgatg
    37201 cgacggaagt acaaatcaat cgccctaaaa aaagaattag cgaattattc tggtaaaaaa
    37261 atgccacgct atgaaggctc aagcgattgt cacaagtcaa gggagaattg tttctttgga
    37321 tatcgctgtg aactattgtc atgatatgaa gttgttcaaa atgagtcgca gaaatatcgg
    37381 acaagctggt aaaatcttgg ctgacagtgg ttatcaaggg ctcatgaaga tatatcctca
    37441 agcacaaact ccacgtaaat ccagcagact caagccacta acagttgaag ataaagccta
    37501 taaccatgcg ctatccaagg agagaagcaa ggttgagaac atctttgcca aagtaaaaac
    37561 gtttaaaatg atttcaacaa cctatcgaaa tcatcgtaaa cacttcggat tacgaatgaa
    37621 tttgattgct ggcattatca atcatgaact aggattctag ttttgcagga agtctattat
    37681 ttggttaggt gaattagtga agcgtttagg caagtgtctc tggttacgac gtcatggact
    37741 ctaaatcgat tatatttagg ggtcatgact agtgaagcag ttagctagtt cgcatataag
    37801 cggctagcgt ctaacaatta ggaactttag ttccaataac tttaagatta cgacgtttta
    37861 ggacataaat cgatcatatt tatgtcctaa aactagtgaa gtatgtccta aaactagtga
    37921 agcgcctagc caaagtccga ataggatttg gcgttagtta cttagattgc tttgcaatca
    37981 agtaactttg gcgatttaca tcttctctgg cgcttctact ccaagcaagc gaagggcttc
    38041 tttgagaacg actgcggttg cgtagctgag ggctagacgg ctgtcgcgtt ctgggctttc
    38101 atccaagata cgtgtatgtg catagtattt gttaaaggat tgagccaggc taattgcaaa
    38161 tttagcaatg atagaaggtt caaagttatc tgccgcacgg ttgataatac gtgggaagtc
    38221 ttgaatgagt ttaatgattt cccagctttc agtatcattc aagctatagt tgccagctgt
    38281 ttctggtttg aaatcggctt tgcgtaagat agattggata cgagcgtagg catattgaac
    38341 gtaaggtcca gtttcaccct cgaaggatac catagcctct aggtcgaagt cgtatccatt
    38401 tgtacggtcg gttttgaggt catagaattt aatggctcca accccaacag catgtgctac
    38461 ttggtctttg ttttctagtt caggattttt agcctcgatt tggaccttgg cacggctaac
    38521 agcctctgca acagtaggct ctagcaagat gacattccct ttacgagtag agagtttctt
    38581 cccttctttt gtaaccaaac caaaaggaac gtgagtaatg tcgtcactcc agtcgtagcc
    38641 catctcttgc aagacagctt tgagctgttt aaagtgggca gattgttctt gaccaacgac
    38701 atagatagat ttagcaaatt ggtattcgtt tttacggtag agggctgcag ccaagtcacg
    38761 tgtgatatag agagttgcac catcagactt cttgatgagg gctggatgtt caattccgta
    38821 tttctcaaga ttcacaactt gggcaccttc tgattcaaga agtagtcctt tttcagaaag
    38881 aatgtctaca actgcatcca tcttatcatt gtagaaggct tctccgttat agctgtcaaa
    38941 ttcaaccttc aattcattgt aaaggcggtt aaattccact aaactttcat cgcggaacca
    39001 ttgccaaaga gcgagagctt cctcatctcc attttcaagt ttacggaacc attcgcgcgc
    39061 ttcttcatcc aagctagggt cattttcagc ttcagcgttg atgcggacat agagtttaag
    39121 gagttcatcg attggatgag cttttacagc ttcttcgtcg ccccattttt tgtaggcaac
    39181 aatcaacatc ccaaattgtt taccccagtc tcccaaatgg ttgaccttga ccgtttgata
    39241 accgattttt tggaaaatat gtgacaagct atctccgata acagttgaac gcaggtggcc
    39301 aatagaaaat ggtttagcga tattcggact agacatgtcg ataacaacat tttcttgttt
    39361 accaatattt tggtcagcat agtgttcttt ttcagtggta acagcttgca atacttgagc
    39421 agaaatggca gatttatcaa ggaaaaagtt aacgtaaggt cctgttgcga caactttttc
    39481 aaaggcttgg ctgttcattt tttcagccag ttcagccgca atcatttgtg gtgctttacg
    39541 ttcgactttg gcaagagaaa aagcagggaa agcgatgtca cccatttctg agtttttagg
    39601 ggtttccagt aactttaaaa tagcctcttg gtccaggcta tcaatgatgc tagccaattc
    39661 gctagcaatc aattcttttg tattcattaa gagctccttt ttggactttt ctactatttt
    39721 atcacaattt taaagaaaga agaaaaaatt tttgaaatct cctgtttttt tggtataata
    39781 tggttataaa tatagttata aatatgcacg caagaggatt ttatgagaaa aagagatcgt
    39841 catcagttaa taaaaaaaat gattactgag gagaaattaa gtacacaaaa agaaattcaa
    39901 gatcggttgg aggcgcacaa tgtttgtgtg acgcagacaa ccttgtctcg tgatttgcgc
    39961 gaaatcggct tgaccaaggt caagaaaaat gatatggtgt attatgtact agtaaatgag
    40021 acagaaaaga ttgatttggt ggaatttttg tctcatcatt tagaaggtgt tgcaagagca
    40081 gagtttacct tggtgcttca taccaaattg ggagaagcct ctgttttggc aaatattgta
    40141 gatgtaaata aggatgaatg gattttagga acagttgctg gtgccaatac cttattggtt
    40201 atttgtcgag atcagcacgt tgccaaactc atggaagatc gtttgctaga tttgatgaaa
    40261 gataagtaag gtcttgggag ttgctctcaa gacttatttt tgaaaaggag agacagaaaa
    40321 tggcgataga aaagctatca cccggcatgc aacagtatgt ggatattaaa aagcaatatc
    40381 cagatgcttt tttgctcttt cggatgggtg atttttatga attattttat gaggatgcgg
    40441 tcaatgctgc gcagattctg gaaatttcct taacgagtcg caacaagaat gccgacaatc
    40501 cgatccctat ggcgggtgtt ccctatcatt ctgcccaaca gtatatcgat gtcttgattg
    40561 agcagggtta taaggtggct atcgcagagc agatggaaga tcctaaacaa gcagttgggg
    40621 ttgttaaacg agaggttgtt caggtcatta cgccagggac agtggtcgat agcagtaagc
    40681 tggacagtca gaataatttt ttggttgcca tagaccgcga aggcaatcaa tttggcctag
    40741 cttatatgga tttggtgacg ggtgactttt atgtgacagg tcttttggat ttcacgctgg
    40801 tttgtgggga aatccgtaac ctcaaggctc gagaagtggt gttgggttat gacttgtctg
    40861 aggaagaaga acaaatcctc agctgccaga tgaatctggt actctcttat gaaaaagaaa
    40921 gctttgaaga ccttcattta ttggatttgc gattggcaac ggtggagcaa acggcatcta
    40981 gtaagctgct ccagtatgtt catcggactc agatgaggga attgaaccac ctcaaacctg
    41041 ttatccgcta cgaaattaag gatttcttgc agatggatta tgcgaccaag gctagtctgg
    41101 atttggttga gaatgctcgc tcaggtaaga aacaaggcag tcttttctgg cttttggatg
    41161 aaaccaaaac ggctatgggg atgcgtctct tgcgttcttg gattcatcgc cccttgattg
    41221 ataaggaacg aatcgtccaa cgtcaagaag tagtgcaggt ctttctcgac catttctttg
    41281 agcgtagtga cttgacagac agtctcaagg gtgtttatga cattgagcgc ttggctagtc
    41341 gtgtttcttt tggcaaaacc aatccaaagg atctcttgca gttggcgact accttgtcta
    41401 gtgtgccacg gattcgtgcg attttagaag ggatggagca acctgctcta gcctatctca
    41461 tcgcacaact ggatgcaatc cctgagttgg agagtttgat tagcgcagcg attgctcctg
    41521 aagctcctca tgtgattaca gatgggggaa ttatccggac tggatttgat gagactttag
    41581 acaagtatcg ttgcgttctc agagaaggga ctagctggat tgctgagatt gaggctaagg
    41641 agcgagaaaa ctctggtatc agcacgctca agattgacta caataaaaag gatggctact
    41701 attttcatgt gaccaattcg caactgggaa atgtgccagc ccactttttc cgcaaggcga
    41761 cgctgaaaaa ctcagaacgc tttggaaccg aagaattagc ccgtatcgag ggagatatgc
    41821 ttgaggcgcg tgagaagtca gccaacctcg aatacgaaat atttatgcgc attcgtgaag
    41881 aggtcggcaa gtacatccag cgtttacaag ctttagccca aggaattgcg acggttgatg
    41941 tcttacagag tctggcggtt gtggctgaaa cccagcattt gattcgacct gagtttggtg
    42001 acgattcaca aattgatatc cggaaagggc gccatgctgt cgttgaaaag gttatggggg
    42061 ctcagaccta tattccaaat acgattcaga tggcagaaga taccagtatt caactgatta
    42121 cagggccaaa catgagtggg aagtctacct atatgcgtca gttagccatg acggcggtta
    42181 tggcccagct gggttcctat gttcctgctg aaagcgccca tttaccgatt tttgatgcga
    42241 tttttacccg tatcggagca gcagatgact tggtttcggg tcagtcaacc tttatggtgg
    42301 agatgatgga ggccaataat gccatttcgc atgcgaccaa gaactctctc attctctttg
    42361 atgaattggg acgtggaact gcaacttatg acgggatggc tcttgctcag tccatcatcg
    42421 aatatatcca tgagcacatc ggagctaaga ccctctttgc gacccactac catgagttga
    42481 ctagtctgga gtctagttta caacacttgg tcaatgtcca cgtggcaact ttggagcagg
    42541 atgggcaggt caccttcctt cacaagattg aaccgggacc agctgataaa tcctacggta
    42601 tccatgttgc caagattgct ggcttgccag cagacctttt agcaagggcg gataagattt
    42661 tgactcagct agagaatcaa ggaacagaga atcctcctcc catgagacaa actagtgctg
    42721 tcactgaaca gatttcactc tttgataggg cagaagagca tcctatccta gcagaattag
    42781 ctaaactgga tgtgtataat atgacaccta tgcaggttat gaatgtctta gtagagttaa
    42841 aacagaaact ataaaaccaa gactcactag ttaatctagc tgtagcaagg agacttcttt
    42901 gacaattctc cacttttttg ctagaatgac atcacacaaa cagaatgaaa aggagctgac
    42961 gcattgtcgc tcccttttgt ctatttttta aggagaaagt atgctgattc agaaaataaa
    43021 aacctacaag tggcaggccc tggcttcgct cctgatgaca ggcttgatgg ttgctagttc
    43081 acttctgcaa ccgcgttatc tgcaggaagt cttaggcgcc ctccttactg ggaaatatga
    43141 agctatttat agtatcgggg cttggttgat tggtgtggcc gtagtcggtc tagttgctgg
    43201 tggactcaat gttgtcctcg cagcctatat tgcccaagga gtttcatccg accttcggga
    43261 ggatgccttc cgtaaaattc aaaccttttc ttatgctgat attgaacaat ttaatgcggg
    43321 aaatctagtc gttcgaatga caaatgatat caaccagatt cagaacgttg tcatgatgac
    43381 cttccagatt cttttcagac ttcccctctt gttcatcggt tcgtttatcc tagcggttca
    43441 aaccttacct tctctgtggt gggtgattgt tctcatggta gtcttgattt ttggtttgac
    43501 tgctgtcatg atgggaatga tggggcctcg ttttgccaag tttcaaaccc ttcttgagcg
    43561 catcaatgcc attgccaagg aaaatttacg tggcgttcgt gtggtcaagt cctttgtcca
    43621 agaaaaagag caatttgcta agtttacaga ggtctcagac gagcttcttg gtcaaaacct
    43681 ttacattggt tatgcctttt cagtagtgga accctttatg atgttggttg gttacggggc
    43741 ggtcttcctc tctatttggc tggtcgcggg aatggttcag tcggatccgt ctgttgttgg
    43801 ttccatcgct tcttttgtta attacctaag ccagattatc tttaccattg ttatggttgg
    43861 atttttggga aattctgtca gccgtgccat gatttccatg cgtcgtattc gagaaattct
    43921 tgacgcagag ccagctatga ccttcaagga tgtcccagat gaagagttgg ttggaagcct
    43981 tagctttgaa aatgtgacct ttacctatcc aatggacaag gaaccgatgc tgaaagatgt
    44041 gagctttact attgaacctg gtcaaatggt tggtgtagtt ggagcgactg gtgcaggaaa
    44101 gtcaaccttg gctcaattga ttccacgtct ctttgatcca caggaagggg ctatcaaaat
    44161 cggaggtaag gatattcgag aagtgagtga aggaaccctg cgtaaaacag tttccatcgt
    44221 tctccaacgt gccattcttt ttagtggaac gattgcagat aacttgagac aggggaaggg
    44281 aaatgctact ctatttgaaa tggagcgcgc agccaatatt gcccaggcta gtgaattcat
    44341 tcatcgtatg gagaaaacct ttgaaagtcc agttgaagaa cggggaacca atttctctgg
    44401 tggacaaaaa caaaggatgt cgattgcgcg tgggattgtc agcaatccac gtattctgat
    44461 ttttgatgat tcgacctcag ccttggatgc caaatcagag cgcttggtgc aagaagcttt
    44521 gaataaggac ttgaagggga cgacaaccat tattattgct caaaaaatta gctcggttgt
    44581 ccatgcagac aagatcttgg ttctaaatca aggacgattg attggtcaag gcacgcatgc
    44641 agacttggtt gccaacaatg ccgtttaccg tgaaatctat gaaacacaga aatgaaagac
    44701 aaactataag aaaagtcaat agttttatct aaactatttc ttatttcaat ttgatgattt
    44761 ggcgatgatt ttagagcacg gcaaaaagcc cttgaaaaag tccatttttt caaaggtaat
    44821 cctgtgttga tttcagaaat tacatcactt tttgttcgtc aaatggcagc tcttttttag
    44881 gatataaaac agggttcgga taagtttttt tgcaaggtgg atgatggcta cattgtaatg
    44941 ttttccttgt tataacttag tcttaagat
//
LOCUS       DAVBBO010000011        43742 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ST1
            SAMEA2066453-rid20184263.denovo.011, whole genome shotgun sequence.
ACCESSION   DAVBBO010000011 DAVBBO010000000
VERSION     DAVBBO010000011.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2066453
            Sequence Read Archive: ERR351777
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 43742)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 43742)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980402.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980402.1
            Genome Coverage       :: 176x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:17:33
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,141
            CDSs (total)                      :: 2,104
            Genes (coding)                    :: 1,953
            CDSs (with protein)               :: 1,953
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 16S)
            partial rRNAs                     :: 1 (23S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 151
            CDSs (without protein)            :: 151
            Pseudo Genes (ambiguous residues) :: 0 of 151
            Pseudo Genes (frameshifted)       :: 73 of 151
            Pseudo Genes (incomplete)         :: 76 of 151
            Pseudo Genes (internal stop)      :: 40 of 151
            Pseudo Genes (multiple problems)  :: 32 of 151
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..43742
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2066453-rid20184263.denovo.011"
                     /strain="ST1"
                     /db_xref="taxon:1313"
     gene            1..296
                     /locus_tag="VQU30_000581"
                     /pseudo
     CDS             1..296
                     /locus_tag="VQU30_000581"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611577.1"
                     /note="frameshifted; internal stop; incomplete; missing
                     N-terminus; Derived by automated computational analysis
                     using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            293..511
                     /locus_tag="VQU30_000582"
     CDS             293..511
                     /locus_tag="VQU30_000582"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000028153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2446745.1"
                     /translation="MSISPRFEALEQAIASKDLEKVREAFKKMNSTWTINESVVRDNS
                     TAHYGRVETAISFLPSSMETEPTDESGT"
     gene            complement(568..852)
                     /locus_tag="VQU30_000583"
     CDS             complement(568..852)
                     /locus_tag="VQU30_000583"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008808933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type B 50S ribosomal protein L31"
                     /protein_id="HET2446746.1"
                     /translation="MARKETMAERKYCKMKKDIHPEYRPVVFMDTTTGYQFLSGSTKR
                     SNETVEFEGETYPLIRVEISSDSHPFYTGRQKFTQADGRVDRFNKKYGLK"
     gene            complement(906..1841)
                     /locus_tag="VQU30_000584"
     CDS             complement(906..1841)
                     /locus_tag="VQU30_000584"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional oligoribonuclease/PAP phosphatase
                     NrnA"
                     /protein_id="HET2446747.1"
                     /translation="MEICQQILEKIKEYNTIIIHRHMKPDPDALGSQVGLKALLEHHF
                     PEKTIKAVGFDEPTLTWMAEMDLVEDRAYQGALVIVCDTANTARIDDKRYSQGDFLIK
                     IDHHPNDDVYGDLSWVDTSSSSASEMITLFAQTTQLALADRDAELLFAGIVGDTGRFL
                     YPSTTARTLRLAAYLREHNFDFAALTRKMDTMSYKIAKLQGYIYDHLEVDENGAARVI
                     LSQKILKQYNVTDAETAAIVGAPGRIDSVSLWGIFVEQADGHYRVRLRSKIHPINEIA
                     KEHDGGGHPLASGANSYSLEENEIIYQKLKNLLKN"
     gene            1945..2388
                     /locus_tag="VQU30_000585"
     CDS             1945..2388
                     /locus_tag="VQU30_000585"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016465724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavodoxin"
                     /protein_id="HET2446748.1"
                     /translation="MALAKIVFASMTGNTEEIADIVADKLRDLGLDVDVDECTTVDAS
                     DFLEADIAIVATYTYGDGELPDEMMDFYEDLADLNLNGKIYGVVGSGDTFYDEFCKAV
                     DDFDRVFVSTGAEKGSECVKVDLSAEEEDIERLEQFAEELAAKVG"
     gene            2504..2770
                     /locus_tag="VQU30_000586"
     CDS             2504..2770
                     /locus_tag="VQU30_000586"
                     /EC_number="5.4.99.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398165.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chorismate mutase"
                     /protein_id="HET2446749.1"
                     /translation="MDLDIIRQEIDQIDDQIVKLLEERMHLVEGVVAYKKASGKPILD
                     TKREEVIFEKVRSRVEDKRYQETIVATFSYILKRSRDYQDQNIK"
     gene            2767..3141
                     /gene="crcB"
                     /locus_tag="VQU30_000587"
     CDS             2767..3141
                     /gene="crcB"
                     /locus_tag="VQU30_000587"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000712114.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fluoride efflux transporter CrcB"
                     /protein_id="HET2446750.1"
                     /translation="MKKEQFYPLGIFLAAMLGGLVRYLVSTWLPASPDFPWGTLFVNY
                     LGIFCLIFLVKGYLVYKGTSKGLILALGTGFCGGLTTFSSLMLDTVKLLDTGRYFSLV
                     LYLLLSIGGGLLLAYYLGRKKW"
     gene            3135..3464
                     /gene="crcB"
                     /locus_tag="VQU30_000588"
     CDS             3135..3464
                     /gene="crcB"
                     /locus_tag="VQU30_000588"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000237393.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fluoride efflux transporter CrcB"
                     /protein_id="HET2446751.1"
                     /translation="MVIVYLAIACGLGALVRYFFSRYNQASKLPLGTLIANLLGCFLI
                     GVFYNHVESKEVYAILATGFCGGLTTFSTLNDELQRLLSDKKVFYSYLTLTYIGGLVA
                     IFLGILL"
     gene            3583..3930
                     /gene="rplS"
                     /locus_tag="VQU30_000589"
     CDS             3583..3930
                     /gene="rplS"
                     /locus_tag="VQU30_000589"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005590628.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L19"
                     /protein_id="HET2446752.1"
                     /translation="MNPLIQSLTEGQLRTDIPSFRPGDTVRVHAKVVEGNRERIQIFE
                     GVVIARKGAGISENYTVRKISNGVGVERIFPIHTPRVEKIEVVRYGKVRRAKLYYLRA
                     LQGKAARIKEIRR"
     gene            3973..4044
                     /locus_tag="VQU30_000590"
     tRNA            3973..4044
                     /locus_tag="VQU30_000590"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:4006..4008,aa:Arg,seq:cct)
     gene            complement(4211..5209)
                     /locus_tag="VQU30_000591"
     CDS             complement(4211..5209)
                     /locus_tag="VQU30_000591"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001008999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SAP domain-containing protein"
                     /protein_id="HET2446753.1"
                     /translation="MNFFSKLFNLKQNNHNRDTNSDCNNFYLNELECGLTPGQLILID
                     WTQKTGRNYNFPRYFKYSLQIDPESTHNQLYKLGYFTKNKTLSYLTVVELKTILSKHN
                     LATSGKKAELITRIINNVNIDNLDIPFEFKLTKEAQNLIIEHSDYIKAYYDKDISMED
                     YCKEKNNISFKATFGDIKWSLLNKQAHRNTVSGDFGCLSNTRKAQGRHLEQEGNIKHA
                     LIYYIESLIITISGLENNFSATDYPVYYPDSIPDYSLKHIQTLMESLSDDDYDFAFDE
                     ALFRFSILNANHFLSKEDIDYLRVNLPRSTAEEINNYLKKYECYSPLNNLELDDFE"
     gene            complement(5252..6058)
                     /gene="yidA"
                     /locus_tag="VQU30_000592"
     CDS             complement(5252..6058)
                     /gene="yidA"
                     /locus_tag="VQU30_000592"
                     /EC_number="3.1.3.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000023490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar-phosphatase"
                     /protein_id="HET2446754.1"
                     /translation="MSIKLIAVDIDGTLVNSQKEITPEVFSAIQDAKEAGVKVVIATG
                     RPIAGVAKLLDDLQLRDQGDYVVTFNGALVQETATGHEIISESLTYEDYLDMEFLSRK
                     LGVHMHAITKDGIYTANRNIGKYTVHESTLVSMPIFYRTPEEMAGKEIVKCMFIDEPE
                     ILDAAIEKIPAEFYERYSINKSAPFYLELLKKNVDKGSAITHLAEKLGLTKDETMAIG
                     DEENDRPMLEVVGNPVVMENGNPEIKKIAKYITKTNDESGVAHAIRTWVL"
     gene            complement(6071..7375)
                     /locus_tag="VQU30_000593"
     CDS             complement(6071..7375)
                     /locus_tag="VQU30_000593"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001003495.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HD domain-containing protein"
                     /protein_id="HET2446755.1"
                     /translation="MNEKVFRDPVHNYIHVNNQIIYDLINTKEFQRLRRIKQLGTSSY
                     TFHGGEHSRFSHCLGVYEIARRITEIFEEKYPEEWNPAESLLTVTAALLHDLGHGAYS
                     HTFENLFDTDHEAITQEIIQNPETEIHQVLLQVAPDFPEKVASVIDHTYPNKQVVQLI
                     SSQIDADRMDYLLRDSYFTGASYGEFDLTRILRVIRPVENGIAFQRNGMHAIEDYVLS
                     RYQMYMQVYFHPATRAMEVLLQNLLKRAKELYPEDKNFFARTSPHLLPFFEKNVTLTD
                     YLALDDGVMNTYFQLWMTSPDKILADLSQRFVNRKVFKSITFSQEDQDQLTSMRKLVE
                     DIGFDPDYYTAIHKNFDLPYDIYRPESQNPRTQIEILQKNGELAELSSLSPIVQSLAG
                     SRHGDNRFYFPKEMLDQNSIFASITQQFLHLIENDHFTPNKN"
     gene            7447..7824
                     /locus_tag="VQU30_000594"
     CDS             7447..7824
                     /locus_tag="VQU30_000594"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000701643.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1934 domain-containing protein"
                     /protein_id="HET2446756.1"
                     /translation="MKIRMRNTIQFDEQLEVIDQLYDVEVHEKGDYSYLLFYNEEKEK
                     VVIKFHGQELMMSRFSNPKTIMRFLKDSDSLAYIPTPMGMQEFIIQTSHYQVDRQKIE
                     LDYQLQNQEGHPFASYQLEITWG"
     gene            7915..8247
                     /locus_tag="VQU30_000595"
     CDS             7915..8247
                     /locus_tag="VQU30_000595"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009660419.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative DNA-binding protein"
                     /protein_id="HET2446757.1"
                     /translation="MEIEKTNRMNALFEFYAALLTDKQMNYIELYYADDYSLAEIAEE
                     FGVSRQAVYDNIKRTEKILEDYEMKLHMYSDYIVRSQIFDQILERYPKDDFLQEQIEI
                     LTSIDNRE"
     gene            8259..9830
                     /gene="ffh"
                     /locus_tag="VQU30_000596"
     CDS             8259..9830
                     /gene="ffh"
                     /locus_tag="VQU30_000596"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000863601.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal recognition particle protein"
                     /protein_id="HET2446758.1"
                     /translation="MAFESLTERLQNVFKNLRKKGKISESDVQEATKEIRLALLEADV
                     ALPVVKDFIKKVRERAVGHEVIDTLNPAQQIIKIVDEELTAVLGSDTAEIIKSPKIPT
                     IIMMVGLQGAGKTTFAGKLANKLKKEENARPLMIAADIYRPAAIDQLKTLGQQIDVPV
                     FALGTEVPAVEIVRQGLEQAQTNHNDYVLIDTAGRLQIDELLMNELRDVKALAQPNEI
                     LLVVDAMIGQEAANVAREFNAQLEVTGVILTKIDGDTRGGAALSVRHITGKPIKFTGT
                     GEKITDIETFHPDRMSSRILGMGDMLTLIEKASQEYDEQKALEMAEKMRENTFDFNDF
                     IDQLDQVQNMGPMEDLLKMIPGMANNPALQNMKVDERQIARKRAIVSSMTPEERENPD
                     LLNPSRRRRIAAGSGNTFVEVNKFIKDFNQAKQLMQGVMSGDMNKMMKQMGINPNNLP
                     KNMPNMGGMDMSALEGMMGQGGMPDLSALGGAGMPDMSQMFGGGLKGKIGEFAMKQSM
                     KRMANKMKKAKKKRK"
     gene            complement(10025..11308)
                     /locus_tag="VQU30_000597"
     CDS             complement(10025..11308)
                     /locus_tag="VQU30_000597"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007554578.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil permease"
                     /protein_id="HET2446759.1"
                     /translation="MKQESTVDLLLDVDQRPSAGKGILLSFQHVFAMFGATILVPLIL
                     GMPVSVALFASGVGTLIYMIATGFKVPVYLGSSFAFITAMSLAMKEMGGDVSAAQTGV
                     ILTGLVYVLVATSIRFVGTKWIDKLLPPIIIGPMIIVIGLGLAGSAVTNAGLVADGNW
                     KNALVAVVTFLIAAFINTKGKGFLRIIPFLFAIIGGYLFALTLGLVDFTPVLKANWFE
                     IPGFYLPFSTGGAFKEYNLYFGPEAIAILPIAIVTISEHIGDHTVLGQICGRQFLKEP
                     GLHRTLLGDGIATSVSAFLGGPANTTYGENTGVIGMTRIASVSVIRNAAFIAIALSFL
                     GKFTALISTIPNAVLGGMSILLYGVIASNGLKVLIKERVDFAQMRNLIIASAMLVLGL
                     GGAILKLGPVTLSGTALSAMTGIILNLILPYENKD"
     gene            complement(11611..12324)
                     /gene="rsmG"
                     /locus_tag="VQU30_000598"
     CDS             complement(11611..12324)
                     /gene="rsmG"
                     /locus_tag="VQU30_000598"
                     /EC_number="2.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (guanine(527)-N(7))-methyltransferase
                     RsmG"
                     /protein_id="HET2446760.1"
                     /translation="MKPKTFYNLLAEQNLPLSDQQKEQFERYFELLVEWNEKINLTAI
                     TDKEEVYLKHFYDSIAPILQGLIPNETIKLLDIGAGAGFPSLPMKILYPELDVTIIDS
                     LNKRINFLQLLAQELDLNGVHFYHGRAEDFAQDKNFRAQYDFVTARAVARMQVLSELT
                     IPYLKVGGKLLALKASNAPEELLEAKNALNLLFSKVEDNLSYALPNRDPRYITVVEKK
                     KETPNKYPRKAGMPNKRPL"
     gene            12418..12978
                     /locus_tag="VQU30_000599"
     CDS             12418..12978
                     /locus_tag="VQU30_000599"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000219838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LemA family protein"
                     /protein_id="HET2446761.1"
                     /translation="MTWIILGVIALIVIFVIVSYNGLVKNRMQTKEAWSQIDVQLKRR
                     NDLLPNLIETVKGYAKYEGSTLEKVAELRNQVAAATSPAEAMKASDALTRQVSGIFAV
                     AESYPDLKASANFVKLQEELTNTENKISYSRQLYNSVVSNYNVKLETFPSNIIAGMFG
                     FKAADFLQTSEEEKSVPKVDFSGLGD"
     gene            12980..13879
                     /gene="htpX"
                     /locus_tag="VQU30_000600"
     CDS             12980..13879
                     /gene="htpX"
                     /locus_tag="VQU30_000600"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000895736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc metalloprotease HtpX"
                     /protein_id="HET2446762.1"
                     /translation="MLFDQIASNKRKTWILLLVFFLLLALVGYAVGYLFIRSGLGGLV
                     IALIIGFIYALSMIFQSTEIVMSMNGAREVDEQTAPDLYHVVEDMALVAQIPMPRVFI
                     IDDPALNAFATGSNPQNAAVAATSGLLAIMNREELEAVMGHEVSHIRNYDIRISTIAV
                     ALASAITMLSSMAGRMMWWGGAGRRRSDDDRDGNGLEIIMLVVSLLAIVLAPLAATLV
                     QLAISRQREFLADASSVELTRNPQGMINALDKLDNSKPMSRHVDDASSALYINDPKKG
                     GGFQKLFYTHPPISERIERLKQM"
     gene            complement(13923..15482)
                     /locus_tag="VQU30_000601"
     CDS             complement(13923..15482)
                     /locus_tag="VQU30_000601"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011681787.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HET2446763.1"
                     /translation="MHYRHSRKGNSMIKINHLTITQNKDLRDLVSDLSMTIQDGEKVA
                     IIGEEGNGKSTLLKTLMGEDLSDFTIKGDIQSDYQSLAYIPQKVPEDLKKKTLHDYFF
                     LDSIDLDYSILYRLAEELHFDSNRFASDQEIGNLSGGEALKIQLIHELAKPFEILFLD
                     EPSNDLDLETVDWLKGQIQKTRQTVIFISHDEDFLSETADTIVHLRLVKHRKEAETLV
                     EHLDYDSYSEQRKANFAKQSQQAANNQRAYDKTMEKHRRVKQNVETALRATKDSTAGR
                     LLAKKMKTVLSQEKRYEKTAQSMTQKPLEEEQIQLFFSDIQPLPASKVLVQLEKENLS
                     IDDRVLAQELQLTVRGQEKIGIIGPNGVGKSTLLAKLQQLLNDKREISLGFMPQDYHK
                     KLQLDLSSIAYISKTGEKEELQKIQSHLASLNFSYPEMQHQIRSLSGGQQGKLLLLDL
                     VLRKPNFLLLDEPTRNFSPTSQPQIRKLFATYPGGLITVSHDRRFLKEVCSIIYRMTE
                     HGLKLVNLEDL"
     gene            complement(15721..16038)
                     /locus_tag="VQU30_000602"
     CDS             complement(15721..16038)
                     /locus_tag="VQU30_000602"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000389556.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helicase BlpT"
                     /protein_id="HET2446764.1"
                     /translation="MEDKKLIQLLSKLNKSYQNCKQGTADDIRLQELLNTTMQELKKT
                     EKLNNSILIDLEKFYQPTSPLIGLGSLKLNDQARTAWRNYDKIHYEHVKHVLSLYGPV
                     FGF"
     gene            16217..16759
                     /locus_tag="VQU30_000603"
     CDS             16217..16759
                     /locus_tag="VQU30_000603"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF177 domain-containing protein"
                     /protein_id="HET2446765.1"
                     /translation="MKLNIQEIRKQSEGLNFEQTLDLVDDLRARNQEILDVKDILAVG
                     KVQYEDRMYFLDYQLSYTIVLASSRSMEPVELVESYPVTEVFMEGATNQLDQEVLDDD
                     LVLPIENGELDLAESVSDNILLNIPIKVLTAEEEAGQGFISGNDWQIMTEEEYQAQQA
                     VKKEENSPFAGLQGLFDGDE"
     gene            16759..17388
                     /gene="nth"
                     /locus_tag="VQU30_000604"
     CDS             16759..17388
                     /gene="nth"
                     /locus_tag="VQU30_000604"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000244461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease III"
                     /protein_id="HET2446766.1"
                     /translation="MVLSKKRARKVLEEIIALFPDAKPSLDFTNHFELLVAVMLSAQT
                     TDAAVNKATPGLFVAFPTPQAMSVATESEIASHISRLGLYRNKAKFLKKCAQQLLDDF
                     DGQVPQTREELESLAGVGRKTANVVMSVGFGIPAFAVDTHVERICKHHDIVKKSATPL
                     EVEKRVMDILPPEQWLAAHQAMIYFGRAICHPKNPECDQYPQLYDFSNL"
     gene            17599..18120
                     /gene="pyrR"
                     /locus_tag="VQU30_000605"
     CDS             17599..18120
                     /gene="pyrR"
                     /locus_tag="VQU30_000605"
                     /EC_number="2.4.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000850024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional pyr operon transcriptional
                     regulator/uracil phosphoribosyltransferase PyrR"
                     /protein_id="HET2446767.1"
                     /translation="MKTKEVVDELTVKRAITRITYEIIERNKDLNKIVLAGIKTRGVF
                     IAHRIQERLKQLENLSVPVVELDTKPFRDDVKSGEDTSLVSVDVTDREVILVDDVLYT
                     GRTIRAAIDNIVGHGRPARVSLAVLVDRGHRELPIRPDYVGKNIPTSRSEEIIVEMTE
                     LDDQDRVLITEEA"
     gene            18139..19062
                     /locus_tag="VQU30_000606"
     CDS             18139..19062
                     /locus_tag="VQU30_000606"
                     /EC_number="2.1.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001293822.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate carbamoyltransferase catalytic
                     subunit"
                     /protein_id="HET2446768.1"
                     /translation="MSENQQALNHVVSMEDLTVDQVMKLIKRGIEFKNGAQLPYEDHP
                     IVSNLFFEDSTRTHKSFEVAEIKLGLERLDFDVKTSSVNKGETLYDTILTLSALGVDV
                     CVIRHPEVDYYRELIASPTITTSIINGGDGSGQHPSQSLLDLMTIYEEFGHFEGLKVA
                     IAGDLDHSRVAKSNMQILKRLGAELFFAGPEEWRSQEFADYGKFVTIDEIIDQVDVMM
                     FLRVQHERHDSGAVFSKEDYHAQHGLTQERYDRLKETAILMHPAPINRDVEIADHLVE
                     APKSRIVQQMTNGVFVRMAILESVLASRNAN"
     gene            19112..20191
                     /gene="carA"
                     /locus_tag="VQU30_000607"
     CDS             19112..20191
                     /gene="carA"
                     /locus_tag="VQU30_000607"
                     /EC_number="6.3.5.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000166701.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine-hydrolyzing carbamoyl-phosphate
                     synthase small subunit"
                     /protein_id="HET2446769.1"
                     /translation="MTKRILVLEDGTVFEGKAFGADIDVTGEIVFNTGMTGYQESITD
                     QSYNGQILTFTYPLVGNYGINRDDYESIIPTCKGVVVFEEARRASNWRNQMTLDEFLK
                     AKKIPGISGIDTRALTKIIRKHGTMRATLTHVGDSMDHVTDQLQATVLPTDNIKQVST
                     KTSYPAPGVGLSVVLVDFGLKHSILRELSKRNCNVTVVPYSTTAEEILHLNPDGVMLS
                     NGPGNPEDVPQALDMIRGVQGKIPIFGICMGHQLFAMANGAKTYKMKFGHRGFNHAVR
                     EIATGRVDFTSQNHGYAVSREDLPEHLIITHEEINDKSVEGVRHRYQPAFSVQYHPDA
                     APGPHDASYLFDEFIEMMEVFKQSN"
     gene            20503..23679
                     /gene="carB"
                     /locus_tag="VQU30_000608"
     CDS             20503..23679
                     /gene="carB"
                     /locus_tag="VQU30_000608"
                     /EC_number="6.3.5.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019803305.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbamoyl-phosphate synthase large subunit"
                     /protein_id="HET2446770.1"
                     /translation="MPKRTDIQKIMVIGSGPIIIGQAAEFDYAGTQACLSLKEEGYEV
                     VLVNSNPATIMTDKEIADKVYIEPITLEFVTRILRKERPDALLPTLGGQTGLNMAMEL
                     SKNGILDELGVELLGTKLSAIDQAEDRDLFKQLMEELEQPIPESEIVNTVEEAVAFAA
                     TIGYPVIVRPAFTLGGTGGGMCANEKELREITENGLKLSPVTQCLIERSIAGFKEIEY
                     EVMRDSADNALVVCNMENFDPVGIHTGDSIVFAPAQTMSDYENQMLRDASLSIIRALK
                     IEGGCNVQLALDPNSFKYYVIEVNPRVSRSSALASKATGYPIAKLAAKIAVGLTLDEV
                     INPVTGSTYAMFEPALDYVVAKIPRFPFDKFEKGERRLGTQMKATGEVMAIGRNIEES
                     LLKACRSLEIGVHHNEIPELAAVSDDALIEKVVKAQDDRLFYVSEAIRRGYTPEEIAE
                     LTKIDIFYLDKLLHIFEIEQELGAHPQDLEVLKTAKLNGFSDRKIAELWGTTDDQVRQ
                     LRLENKIVPVYKMVDTCAAEFDSETPYFYSTYGWENESIRSDKESVLVLGSGPIRIGQ
                     GVEFDYATVHSVKAIQAAGYEAIIMNSNPETVSTDFSVSDKLYFEPLTFEDVMNVIDL
                     EQPKGVIVQFGGQTAINLAEPLAKAGVTILGTQVADLDRAEDRDLFEQALKELDIPQP
                     PGQTATNEEEAALAARKIGFPVLVRPSYVLGGRAMEIVENEEDLRSYMRTAVKASPDH
                     PVLVDSYIVGQECEVDAISDGKNVLIPGIMEHIERAGVHSGDSMAVYPPQTLSQKVQE
                     TIADYTKRLAIGLHCLGMMNIQFVIKDEKVYVIEVNPRASRTVPFLSKVTNIPMAQVA
                     TKLILGQSLSELGYQNGLYPESTRVHIKAPVFSFTKLAKVDSLLGPEMKSTGEVMGSD
                     ATLEKALYKAFEASYLHLPTFGNVVFTIADDAKEEALNLARRFQNIGYGILATEGTAA
                     FFASHGLQAQPVGKIGDDDKDIPSFVRKGRIQAIINTVGTKRTADEDGEQIRRSAIEH
                     GVPLFTALDTANAMLKVLESRSFVTEAI"
     gene            complement(23954..24763)
                     /locus_tag="VQU30_000609"
     CDS             complement(23954..24763)
                     /locus_tag="VQU30_000609"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001199643.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphorylcholine transferase LicD"
                     /protein_id="HET2446771.1"
                     /translation="MQYLEKKEIKEIQLALLDYIDETCKKHDIPYFLSYGTMLGAIRH
                     KGMIPWDDDIDISLYREDYERLLKIIEEENHPRYKVLSYDTSSWYFHNFASILDTSTV
                     IEDHVKYKRHDTSLFIDVFPIDQFTDLSIVDKSYKYVALRQLAYIKKSRAVHGDSKLK
                     DFLRLCSWYALRFVNPRYFYKKIDQLVKNAVTNIPQYEGGVGIGKEGMKEIFPVDTFK
                     ELILTEFEGRMLPVPKKYDQFLTQMYGDYMTPPSKEMQEWYSHSIKAYRKN"
     gene            complement(24765..25568)
                     /locus_tag="VQU30_000610"
     CDS             complement(24765..25568)
                     /locus_tag="VQU30_000610"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004259727.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphorylcholine transferase LicD"
                     /protein_id="HET2446772.1"
                     /translation="MKQLTVEDAKQIELEILNYIDTLCKKHNINYIINYGTLIGAVRH
                     EGFIPWDDDIDLSMPREDYQRFINIFQKEKSKYKLLSLETDKNYFNNFIKITDSTTKI
                     IDTRNTKTYESGIFIDIFPMDRFDDPKVIDTCYKLESFKLLSFSKHKNIVYKDSLLKD
                     WIRTAFWLLLRLVSPRYFANKIEKEIQKYSRENGQYMAFIPSKFKEKEVFPSATFDKT
                     IDLPFENLSLPAPEKFDTILTQFYGDYMTLPPEEKRFYSHEFHAYKLED"
     gene            complement(25578..27065)
                     /gene="tacF"
                     /locus_tag="VQU30_000611"
     CDS             complement(25578..27065)
                     /gene="tacF"
                     /locus_tag="VQU30_000611"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000835918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IV teichoic acid flippase TacF"
                     /protein_id="HET2446773.1"
                     /translation="MKSIKLNALSYMGIRVLNIIFPILTGTYVARVLDRTDYGYFNSV
                     DTILSFFLPFATYGVYNYGLRAISNVKDNKKDLNRTFSSLFYLCIACTILTTAVYILA
                     YPLFFTDNPIVKKVYLVMGIQLIAQIFSIEWVNEALENYSFLFYKTAFIRILMLVSIF
                     LFVKNEHDIVVYTLVMSLSTLINYLISYFWIKRDIKLVKIHLSDFKPLFLPLTAMLVF
                     ANANMLFTFLDRLFLVKTGIDVNVSYYTIAQRIVTVIAGVVTGAIGVSVPRLSYYLGK
                     GDKEAYVSLVNRGSRIFNFFIIPLSFGLMVLGPNAILLYGSEKYIGGDILTSLFAFRT
                     IILALDTILGSQILFTNGYEKRITVYTVFAGLLNLGLNSLLFFNHIVAPEYYLLTTML
                     SEASLLVFYIIFIHRKQLIHLGHIFSYTVRYSLFSLSFVAIYFLINFVYPVDMVINLP
                     FLINTGLIVLLSAISYISLLVFTKDSIFYEFLNHVLALKNKFKKS"
     gene            27401..28108
                     /locus_tag="VQU30_000612"
     CDS             27401..28108
                     /locus_tag="VQU30_000612"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016465903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-C-methyl-D-erythritol 4-phosphate
                     cytidylyltransferase"
                     /protein_id="HET2446774.1"
                     /translation="MIYAGILAGGTGTRMGISNLPKQFLELGDRPILIHTIEKFVLEP
                     SIEKIVVGVHGDWVSHAEDLVDKYLPLYKERIIITKGGADRNTSIKKIIEAIDAYRPL
                     TPEDIVVTHDSVRPFITLRMIQDSIQLAQNHDAVDTVVEAVDTIVESTNGQFITDIPN
                     RAHLYQGQTPQTFRCKDFMDLYGSLSDEEKEILTDACKIFVIKGKDVALAKGEYSNLK
                     ITTVTDLKIAKSMIEKD"
     gene            28113..29135
                     /locus_tag="VQU30_000613"
     CDS             28113..29135
                     /locus_tag="VQU30_000613"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004257983.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alcohol dehydrogenase catalytic
                     domain-containing protein"
                     /protein_id="HET2446775.1"
                     /translation="MINQIYQLTKPKFINVKYQEEAIDQENHILIRPNYMAVCHADQR
                     YYQGKRDPKILNKKLPMAMIHESCGTVISDPTGTYEVGQKVVMIPNQSPMQSDEEFYE
                     NYMTGTHFLSSGFDGFMREFVSLPKDRVVAYDAIEDTVAAITEFVSVGMHAMNRLLTL
                     AHSKRERIAVIGDGSLAFVVANIINYTLPEAEIVVIGRHWEKLELFSFAKECYITDNI
                     PEELAFDHAFECCGGDGTGPAINDLIRYIRPQGTILMMGVSEYKVNLNTRDALEKGLI
                     LVGSSRSGRIDFKNAIQMMEVKKFANRLKNILYLEEPVREIKDIHRVFATDLNTAFKT
                     VFKWEV"
     gene            29152..30021
                     /gene="licA"
                     /locus_tag="VQU30_000614"
     CDS             29152..30021
                     /gene="licA"
                     /locus_tag="VQU30_000614"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000411210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choline kinase LicA"
                     /protein_id="HET2446776.1"
                     /translation="MEKIIKEKISSLLSQEEEVLSVEQLGGMTNQNYLAKTTNKQYIV
                     KFFGKGTEKLINRQDEKYNLELLKDLGLDVKNYLFDIEAGIKVNEYIESAITLDSTSI
                     KTKFDKIAPILQTIHTSAKELRGEFAPFEEIKKYESLIEEQIPYANYESVRNAVFSLE
                     KRLADLGVDRKSCHIDLVPENFIESPQGRLYLIDWEYSSMNDPMWDLAALFLESEFTS
                     QEEETFLSHYESDQTPVSHEKIAIYKILQDTIWSLWTVYKEEQGEDFGDYGVNRYQRA
                     VKGLASYGGSDEK"
     gene            30011..30889
                     /locus_tag="VQU30_000615"
     CDS             30011..30889
                     /locus_tag="VQU30_000615"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000837620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DMT family transporter"
                     /protein_id="HET2446777.1"
                     /translation="MKSKNGVPFGLLSGIFWGLGLTVSAYIFSIFTDLSPFVVAAAHD
                     FLSIFILLAFLLVKEGKVRLSIFLNIRNVSVIIGALLAGPIGMQANLYAVKYIGSSLA
                     SSVSAIYPAISVLLAFFFLKHKISKNTVFGIVLIIGGIIAQTYKVEQVNSFYIGILCA
                     LVCAIAWGSESVLSSFAMESELSEIEALLIRQVTSFLSYLVIVLFSHQSFTAVANGQL
                     LGLMIVFAAFDMISYLAYYIAINRLQPAKATGLNVSYVVWTVLFAVVFLGAPLDMLTI
                     MTSLVVIAGVYIIIKE"
     gene            30901..31590
                     /locus_tag="VQU30_000616"
     CDS             30901..31590
                     /locus_tag="VQU30_000616"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NTP transferase domain-containing protein"
                     /protein_id="HET2446778.1"
                     /translation="MKAIILAAGLGTRLRPMTENTPKALVQVNQKPLIEYQIEFLKEK
                     GINDIIIIVGYLKEQFDYLKEKYGVRLVFNDKYADYNNFYSLYLVKEELANSYVIDAD
                     NYLFKNMFRNDLTRSTYFSVYREDCTNEWFLVYGDDYKVQNIIVDSKAGRILSGVSFW
                     DAPTAEKIVSFIDKAYASGEFVDLYWDNMVKDNIKELDVYVEELEGNSIYEIDSVQDY
                     HKLEEILKNEN"
     gene            31688..32536
                     /gene="dprA"
                     /locus_tag="VQU30_000617"
     CDS             31688..32536
                     /gene="dprA"
                     /locus_tag="VQU30_000617"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004257994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-protecting protein DprA"
                     /protein_id="HET2446779.1"
                     /translation="MKITNYEIYKLKKSGLTNQQILKVLEYGENVDQELLLGDIADIS
                     GCRNPAVFMERYFQIDDAHLSKEFQKFPSFSILDDCYPWDLSEIYDAPVLLFYKGNLD
                     LLKFPKVAVVGSRACSKQGAKSVEKVIQGLENELVIVSGLAKGIDTAAHMAALQNGGK
                     TIAVIGTGLDVFYPKANKRLQDYIGNDHLVLSEYGPGEQPLKFHFPARNRIIAGLCRG
                     VIVAEAKMRSGSLITCERAMEEGRDVFAIPGSILDGLSDGCHHLIQEGAKLVTSGQDV
                     LAEFEF"
     gene            33420..34463
                     /locus_tag="VQU30_000618"
     CDS             33420..34463
                     /locus_tag="VQU30_000618"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001861634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR00341 family protein"
                     /protein_id="HET2446780.1"
                     /translation="MTNNKLYSLIEFRNKIYEELELSRSDLAILLCAMLIASIGLNMD
                     STPVIIGAMLISPLMTPILGVGLSLAIFDFKLLRKSFKILAIQILASLIASTLYFYLS
                     PISYASSEIVARTSPTIWDVLIAFVGGIAGIIGARKKETNNIVPGVAIATALMPPLCT
                     VGYAIASANLKFIIGSSYLFLINCSFIVIATYIGVRLMMVKKHYFKDNEEDSKMRRIL
                     LLVAVLLMIPSFISATTLVRETLKKESLKKFISEQFQGHNILKKTYSKKTHTLKLTIS
                     GNYLTEEELDMISSKRGDYGLSDVSVQVSQLSDSEQLSKEELVEYFFQYIKDKEAKEK
                     EKANKFYTESEEQ"
     gene            34630..36717
                     /gene="topA"
                     /locus_tag="VQU30_000619"
     CDS             34630..36717
                     /gene="topA"
                     /locus_tag="VQU30_000619"
                     /EC_number="5.6.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000179642.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I DNA topoisomerase"
                     /protein_id="HET2446781.1"
                     /translation="MATATKKKKSTVKKNLVIVESPAKAKTIEKYLGRNYKVLASVGH
                     IRDLKKSSMSVDIENNYEPQYINIRGKGPLINDLKKEAKKANKVFLASDPDREGEAIS
                     WHLAHILNLDENDANRVVFNEITKDAVKNAFKEPRKIDMDLVDAQQARRILDRLVGYS
                     ISPILWKKVKKGLSAGRVQSIALKLIIDRENEINAFQPEEYWTVDAVFKKGTKQFHAS
                     FYGVDGKKMKLTSNDEVKEVLSRLTSKDFSVDQVDKKERKRNAPLPYTTSSMQMDAAN
                     KINFRTRKTMMVAQQLYEGINIGSGVQGLITYMRTDSTRISPVAQNEAASFITDRFGS
                     KYSKHGSKVKNASGAQDAHEAIRPSSVFNTPESIAKYLDKDQLKLYTLIWNRFVASQM
                     TAAVFDTMAVKLSQNGVQFAANGSQVKFDGYLAIYNDSDKNKMLPDMVVGDVVKQVNS
                     KPEQHFTQPPARYSEATLIKTLEENGVGRPSTYAPTIETIQKRYYVRLAAKRFEPTEL
                     GEIVNKLIVEYFPDIVNVTFTAEMEGKLDDVEVGKEQWRRVIDAFYKPFSKEVAKAEE
                     EMEKIQIKDEPAGFDCEVCGSPMVIKLGRFGKFYACSNFPDCRHTQAIVKEIGVECPS
                     CHQGQIIERKTKRNRLFYGCNRYPECEFTSWDKPVGRDCPKCGNFLMEKKVRGGGKQV
                     VCSKGDYEEEKIK"
     gene            36938..37297
                     /locus_tag="VQU30_000620"
     CDS             36938..37297
                     /locus_tag="VQU30_000620"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004258004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YbaN family protein"
                     /protein_id="HET2446782.1"
                     /translation="MRIIYLIIGFLSLTLAIVGVVLPLLPTTPFLLLSIACFSRSSKR
                     FEDWLYHTKLYQAYVADFRETKSIARERKKKIIVSIYVLMGISIYFAPLLPVKIGLGA
                     LTIFITYYLFKVIPDKE"
     gene            37390..38022
                     /locus_tag="VQU30_000621"
     CDS             37390..38022
                     /locus_tag="VQU30_000621"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000638771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="copper homeostasis protein CutC"
                     /protein_id="HET2446783.1"
                     /translation="MIYEFCAENVTLLEKAMQAGARRIELCDNLAVGGTTPSYGVTKA
                     AVELAANYDTTIMTMIRPRGGDFVYNDLEIAIMLEDIRLTAQAGSQGVVFGALTADKK
                     LDKPNLEKLIAASKGMEIVFHMAFDELSDEDQPEAIDWLSQAGVTRILTRAGVSGDSL
                     EKRFVHYHRILEYAKGKIEILPGGGIDLENRQTFIDQVGVTQLHGTKVVF"
     gene            38066..38722
                     /locus_tag="VQU30_000622"
     CDS             38066..38722
                     /locus_tag="VQU30_000622"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000461593.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MmcQ/YjbR family DNA-binding protein"
                     /protein_id="HET2446784.1"
                     /translation="MFEIFKSYQFNQEKAHDYGFIENSEVWTYSCQILQGDFVMTVSI
                     TADNVNFQVFDQETGDLYPHVYMESMRGSFVGNVREACLEILYQIRKACFDVQDFICH
                     QTKRIMTQVQEKYGNQLEYLWEKSPDTAVLRHEGNQKWYAVLMKISWNKLEKGREGQV
                     EAVNLKHDQVANLLSQKGIYPAFHMSKRYWISVSLDDTLSDEEVLELIEKSWNLTSKK
                     "
     gene            38741..39835
                     /locus_tag="VQU30_000623"
     CDS             38741..39835
                     /locus_tag="VQU30_000623"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001010962.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-isopropylmalate synthase"
                     /protein_id="HET2446785.1"
                     /translation="MNFQLAKYSLLKRFLENIGFTTLEEYGAIFKYLIENVKTDRQII
                     YSPHCHDDLGMAVANSLAAVKNGAGRVEGTINGIRERAENAALEEIAVALNIRQDYYQ
                     VETSIVLNETINTSEMVSRFSGIPVPKNKAVVGGNTFSHESGIHQDGVLKNPLTYEII
                     TPELVGVKILLGKLSGRHAFVEKLRELALDFTEEDIKPLFAKFKALVDKKQEITDADI
                     RALVAGTMVENPEGFHFDDLQLQTHADNDIEALVSLANMDGEKVEFNATGQGSVEAIF
                     NAIDKFFNQSVRLVSYTIDAVTDGIDTQDRVLVTVENRDTETIFNAAGLDFDVLKASA
                     IVYINANTFVQKENAGEMGRSVSYHDMPSV"
     gene            39847..40884
                     /gene="leuB"
                     /locus_tag="VQU30_000624"
                     /pseudo
     CDS             39847..40884
                     /gene="leuB"
                     /locus_tag="VQU30_000624"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399454.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="3-isopropylmalate dehydrogenase"
     gene            40881..41150
                     /locus_tag="VQU30_000625"
     CDS             40881..41150
                     /locus_tag="VQU30_000625"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000762418.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1294 domain-containing protein"
                     /protein_id="HET2446786.1"
                     /translation="MKLDEKITLVLLIWNVIIFLIYGIDKSKARRRVWRIPEKILLIL
                     AFTFGGFGAWLAGIIFHHKTRKWYFKIVWFLGMVTTLVALYFIWR"
     gene            41154..41513
                     /gene="leuD"
                     /locus_tag="VQU30_000626"
     CDS             41154..41513
                     /gene="leuD"
                     /locus_tag="VQU30_000626"
                     /EC_number="4.2.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-isopropylmalate dehydratase small subunit"
                     /protein_id="HET2446787.1"
                     /translation="MAGSSREYAAWALADYGFKVVIAGSFGDIHYNNELNNGMLPIVQ
                     PREVREKLAQLKPTDQVTVDLEQQKIISPVEEFTFEIDSEWKHKLLNSLDDIGITLQY
                     EELIAAYEKQRPAYWQD"
     gene            41675..42243
                     /locus_tag="VQU30_000627"
                     /pseudo
     CDS             41675..42243
                     /locus_tag="VQU30_000627"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019771122.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="translation factor (SUA5)"
     gene            42337..42402
                     /locus_tag="VQU30_000628"
                     /pseudo
     CDS             42337..42402
                     /locus_tag="VQU30_000628"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001849983.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="translation factor (SUA5)"
     gene            42565..>43742
                     /locus_tag="VQU30_000629"
     CDS             42565..>43742
                     /locus_tag="VQU30_000629"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001042398.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="McrB family protein"
                     /protein_id="HET2446788.1"
                     /translation="MNKRKVSLEDFYKWYSLNKEELLNKATVGEKFNDKLKEEFLQEW
                     PLDRILTMSIDEYVIGKGQQNKSLCYALEKGKYKNLFLGISGGSASKFGIYWNKKTNK
                     YKDQANNEISELDQRFSKLKSDLYEIIKEGIRFNFENPIFDMKRSTNEFIGRSAMVTK
                     LLCIYTEGDPFFGVNINSQKEFWNHFVSQTNQGGPYLQNHKIIELMSKTYPELEPSKL
                     GTMLFEYSKLFMENKEDNSTMDSSNNFRHQLTQSLLKSPNLILRGAPGTGKTYLAKEI
                     AKELTDGNEDQIGFVQFHPSYDYTDFVEGLRPVSNGDGAIEFRLQDGIFKDFCQKAKE
                     TQLIGGQDNFDEAWDSYLEYINVAEEKEYITKTSYLSVNSRQNLSVNYDSGVPGWSLP
                     "
BASE COUNT        13273 a         7821 c         9446 g        13202 t
ORIGIN      
        1 gcttatccag atgattatct tttactcgtt atggacaatg ctatatggca taaatcaagt
       61 gccttaaaga ttccgactaa tattggcttt gcatttattc ctccatacac accagagatg
      121 aacccattga acaagtgtgg aaagagattc gtaaacgtgg atttaagaat aaagcctttt
      181 aaactttgga agatgtcatg aatcaactcc aagatgttat acaaggactg gagaaggagg
      241 tgataaagtc catcgttaat cggagatgga ctagaatgct ttttgaaagc agatgagtat
      301 aagtcctcgt tttgaagcct tggaacaggc cattgcctcc aaagatttgg aaaaagtccg
      361 agaagctttt aagaaaatga attccacttg gaccatcaat gaaagtgtgg ttcgtgacaa
      421 tagtacagct cattatggac gtgttgaaac agctatttcc ttcctgccta gtagcatgga
      481 aaccgaacct acagatgagt ctggaacatg aaaacagcag ttgatttcaa gaaacaaaaa
      541 agaacagtcg aaactgttct tttatcatta tttgagaccg tattttttgt tgaaacgatc
      601 cacgcgtcca tctgcttgag tgaacttttg acgtccagtg tagaatgggt gtgagtctga
      661 tgaaatttcc acacggatca atgggtaagt ttcgccttcg aactcaactg tttcgttaga
      721 gcgttttgtt gaaccgctaa ggaattggta accagtagtt gtgtccatga agacaactgg
      781 gcgatattct ggatggatat cttttttcat tttgcaatat ttcctttctg ccatggtctc
      841 tttgcgagcc atagattgtt accatactag tctatcagat tctgaaaagt ttggcaagta
      901 ttttatcagt ttttaagcaa gttttttaac ttttggtaga tgatttcatt ttcttctagg
      961 ctataggaat tagcaccact tgctagaggg tggcctccac catcatgctc cttggcgatt
     1021 tcattgatag gatggatttt actgcgtaag cgaacgcggt agtggccatc agcctgttcc
     1081 acaaaaattc cccagagact aacactatca atacgcccag gtgcacctac aatggccgca
     1141 gtttcagcat cggttacatt gtattgtttc aagattttct gactcaggat aacgcgagca
     1201 gcaccatttt catccacttc cagatggtcg tagatgtagc cttgcagttt agcaattttg
     1261 tagctcatag tgtccatttt gcgagtgaga gccgcaaagt caaagttatg ttctctcaaa
     1321 taagcagcca ggcgaagagt ccgtgcagtg gtagaagggt agaggaagcg acctgtatca
     1381 ccgacaattc ctgcaaagag caactcagca tcgcgatctg ccaaggctag ttgggttgtt
     1441 tgggcaaata gggtaatcat ctcgctagcg ctacttgaac tagtatcgac ccaagacagg
     1501 tcaccgtata catcatcatt tggatggtgg tcaatcttaa tgagaaaatc accttgacta
     1561 tagcgcttat catcgatacg agcagtatta gctgtatcac agacgatgac aagtgcgcct
     1621 tggtaggctc tatcttcaac aagatccatc tcagccatcc aagtaagagt tggttcatca
     1681 aaaccgacgg ctttgatggt tttttctggg aaatgatgtt ccagcaaggc tttcaatccc
     1741 acctgacttc ccaaggcatc agggtctggt ttcatatgac gatgaatgat aatggtgttg
     1801 tattctttaa ttttttctaa aatttgttgg caaatctcca taaataacct caattctttc
     1861 tcatttcatt gtagcacaag aatttttatt tttaaaatga aaaagatgtg atataatgga
     1921 gaaagataaa ttgaggagga cgatatggca ttagcaaaaa ttgtatttgc cagtatgacc
     1981 ggtaataccg aagaaattgc agatattgta gcagacaaat tacgtgactt gggcttggat
     2041 gttgatgttg atgaatgtac aactgttgac gcttcagact tcttggaagc agacatcgct
     2101 atcgttgcga cctatactta tggtgatggt gaattgccag atgagatgat ggacttctac
     2161 gaagacctag cagatctcaa cttgaatggc aaaatctacg gagtggtcgg ctcaggagat
     2221 accttctacg atgaattctg taaggctgtt gatgactttg accgtgtctt tgtgtcaaca
     2281 ggagcagaaa aaggttcaga gtgtgttaaa gttgatcttt ctgccgagga agaagatatt
     2341 gaacgcttgg aacaattcgc agaagaattg gctgctaaag taggataagc ataaaagtgc
     2401 gctgatgtaa tcaatcagtg catttttctt atcgagagtt gggattttac tagcctaatt
     2461 gatggctttt tgatacaata attcaaataa aggaggagac tgtatggatt tagatattat
     2521 tcgtcaagaa atcgatcaaa tcgacgacca aattgtcaaa ctgttagaag aacgaatgca
     2581 tttagttgag ggggtggttg cttataagaa agcttcaggt aaaccgattt tagatactaa
     2641 gagagaagaa gttatttttg aaaaggttag gagtcgtgta gaggacaagc gctatcagga
     2701 gactattgtc gcgacttttt cgtacatact caaacgttcg cgtgattatc aggatcaaaa
     2761 tatcaaatga aaaaagaaca attttatccg ctaggaattt ttctagctgc tatgttgggc
     2821 ggacttgtcc gatatctagt ttccacctgg ttaccagcca gtccagactt tccttggggc
     2881 actctctttg tcaactatct gggaattttc tgcttgattt ttcttgtcaa gggctatctg
     2941 gtctataagg ggactagtaa gggcttgatt ttagcactgg ggacgggttt ttgcggaggt
     3001 ttaacaactt tttccagcct aatgcttgat actgtgaagc tgcttgatac agggcgttat
     3061 tttagtttag tcctgtattt gcttttgagt atcggtggag gcctgctttt agcttactat
     3121 ttggggagga agaaatggta atcgtctatc ttgcaatcgc ctgtggcttg ggagcactcg
     3181 tacggtattt cttttctcgc tataatcaag cttctaaatt gccactcgga acgctcatag
     3241 ctaatctttt aggttgtttt ttaattggag tattctacaa tcatgtagag tctaaggaag
     3301 tatatgctat tctagcaaca ggattttgtg gcggtttaac aactttttcg accttgaatg
     3361 acgaacttca aagactgcta agtgataaga aggtctttta ttcttacctg actttgactt
     3421 acataggtgg tttggttgcg atttttttag gaattttgct ataaatttct ttactttttt
     3481 ttagaaattt ggtaaactat atcttgtgtg taatggacgc acaaaaatac agtttatccg
     3541 ctgaggaaga ttcctcaaga ttgacaaaga taggagaata aaatgaatcc attaatccaa
     3601 agcttgactg aaggtcaact tcgtacagat atcccatcat tccgtcctgg tgacactgtt
     3661 cgtgtacatg cgaaagttgt cgaaggtaac cgtgaacgta tccagatttt tgaaggtgtt
     3721 gttattgcac gtaaaggtgc tggcatctct gaaaactaca cagttcgtaa aatctctaac
     3781 ggtgtaggtg ttgagcgtat cttcccaatc cacactccac gtgttgaaaa aatcgaagtt
     3841 gtacgttacg gtaaagtacg tcgtgcgaaa ttgtactact tgcgtgctct tcaaggtaag
     3901 gcagctcgta tcaaagaaat ccgtcgttaa ttcgactaaa aaactctgct ttttcagcag
     3961 agtttttatc tagctccctt agttcaatgg atataacaac tccctcctaa ggagtagttg
     4021 caggttcgat tcctgcaggg ggcatgtaat tagatatcaa agaagtttgt caaagagtct
     4081 ttgatattaa aagaacgcat aatatagggg attgtctcca taatattatg cgttttatta
     4141 ttgaaaaatt tgggcaatca tcagataaaa ttgagactat atcgagtata taaatgtttg
     4201 tatagtcaat ttattcaaaa tcgtcaagtt ctaaattatt taaaggacta taacattcat
     4261 atttctttaa gtaattgttt atttcttcag cagtggaacg aggtaaatta actcttaaat
     4321 agtcaatatc ttccttagat aaaaaatgat ttgcattcaa aattgagaag cgaaataatg
     4381 cttcatcaaa agcaaaatca taatcgtcat cagataatga ttccattaat gtttgaatat
     4441 gttttagtga gtagtcaggt atcgaatcgg gataatatac tggataatca gtggctgaaa
     4501 aattgttttc taatcctgaa atagtaatta tcaaagattc tatgtaatat attaaagcat
     4561 gtttaatatt accttcttgt tccaaatgtc ttccctgagc ctttcgtgtg ttagataagc
     4621 atccaaaatc tcctgataca gtattcctat gagcttgttt atttaagaga ctccatttta
     4681 tatcaccaaa agttgcttta aaagagatat tgtttttttc tttacaataa tcttccatac
     4741 ttatgtcttt atcatagtat gctttgatat agtcactatg ttcgataata agattttgtg
     4801 cttcttttgt tagtttaaat tcgaacggaa tatctaaatt gtcaatgtta acattattaa
     4861 ttattcttgt aattaattct gctttttttc cagaagtagc taaattatgt ttagataata
     4921 tagtttttaa ttctactact gtaagatatg ataaagtctt atttttagtg aagtatccta
     4981 atttgtataa ttgattgtgt gtagattcag ggtcaatttg aagagagtat ttaaaatatc
     5041 ttgggaaatt ataatttctc cctgtttttt gagtccaatc tatgagtatg agttgcccag
     5101 gagtaaggcc acattctaat tcgtttaggt aaaaattgtt acaatcagaa tttgtgtctc
     5161 tattatgatt attttgtttt aaattaaata gtttgctaaa aaaattcatt ggattttatt
     5221 gctaatcaat tcttattgaa aaatgatact tttacagtac ccatgttcgg atggcatggg
     5281 caacgccgga ttcgtcattt gttttggtga tgtatttggc gatttttttg atttctggat
     5341 ttccattttc catgacaacg gggtttccaa cgacttccag catgggacgg tcattttctt
     5401 catcaccgat tgccatggtt tcatctttgg tcaatccgag tttttcagcc aagtgagtaa
     5461 tggctgaacc cttgtctaca ttctttttaa ggagttcgag gtagaaagga gcagatttgt
     5521 tgatggagta gcgctcgtaa aattctgctg gaattttttc aatcgcagca tcgagaattt
     5581 ctggttcatc gataaacata catttaacaa tttctttgcc agccatttct tcaggggtac
     5641 ggtagaagat aggcatgctg acgagggttg attcgtgtac agtgtatttt ccgatattgc
     5701 gatttgcagt atagataccg tccttggtaa tggcatgcat gtggacaccg agcttgcgac
     5761 tgaggaattc catatccaga taatcctcat aggtcaagga ttcgctgata atctcatggc
     5821 cagtagcagt ttcttggaca agggcaccat tgaaggtcac cacatagtca ccttggtctc
     5881 tcaactgcaa gtcgtccaga agtttggcaa cacctgcgat ggggcggcca gttgcaatca
     5941 cgactttgac accagcttct ttggcatctt ggatggcaga aaagacttca ggagtgattt
     6001 ccttttggct gttgactagg gttccgtcaa tatcgacggc aattagttta atactcataa
     6061 aattcctctt ctagttttta tttggggtaa aatgatcgtt ctcaatcaag tgtaaaaatt
     6121 gctgggtaat gcttgcgaag atgctgtttt ggtctaacat ttctttaggg aaatagaaac
     6181 gattatctcc gtggcgactg ccagcaaggg attggacgat aggagacagg ctagagagtt
     6241 cggccagttc tccatttttt tgtaaaatct caatctgtgt ccgtggattt tgagattcgg
     6301 gacgatagat atcataaggg aggtcaaagt tcttatgaat ggcagtatag tagtcgggat
     6361 caaagccgat gtcctcaacc aattttctca tgctagtaag ttgatcttgg tcctcttgtg
     6421 aaaaggtaat ggatttaaag accttgcggt tgacaaagcg ttgagataaa tctgcaagaa
     6481 ttttgtcagg actagtcatc caaagctgga agtaggtatt catcacgcca tcatccagag
     6541 ccagatagtc agtcaaggtc acattttttt cgaagaaagg caggagatgt ggggaagttc
     6601 gtgcaaagaa attcttgtcc tcagggtaga gttccttggc gcgcttgaga agattctgta
     6661 ggagaacttc catggcgcgt gttgctgggt ggaaataaac ctgcatgtac atctggtagc
     6721 gactgaggac gtagtcttcg atggcgtgca tgccattgcg ctgaaaggcg ataccatttt
     6781 cgacaggacg aatgactcgg aggatgcgag tcaggtcaaa ttccccatag gatgctcctg
     6841 taaaatagga gtcgcgcaag agatagtcca tgcgatctgc gtcaatctga ctagaaatga
     6901 gctgcacgac ctgcttatta ggataggtat ggtcaatgac actggccacc ttttctggga
     6961 aatcaggtgc cacttgtagc aggacttggt gaatctctgt ctcaggattt tgaataatct
     7021 cctgagtaat ggcttcatgg tctgtatcaa agagattttc aaaagtatgg gagtaggcac
     7081 catgcccaag gtcgtgtagg agagcagcgg tcacggtcaa gagagactcg gcaggattcc
     7141 attcctcagg atatttttct tcgaaaatct ctgtgatgcg tcgtgcaatt tcatagactc
     7201 ctagacagtg agagaagcga ctgtgttctc caccgtggaa ggtataactg gaagttccca
     7261 gttgtttgat ccggcgcaaa cgctgaaatt cttttgtatt aatcaagtca tagatgattt
     7321 gattattgac atggatgtag ttgtgaactg ggtcacggaa tactttttcg ttcatatgac
     7381 cattatagca aaatcctgct ctttttggta aaatagtagg acaagagaca agaaagaggg
     7441 cctgatgtga agattcggat gcgaaataca attcagtttg atgagcagtt ggaagtgatt
     7501 gaccagcttt atgatgtgga agtgcatgaa aaaggagatt atagctacct gcttttctat
     7561 aatgaggaaa aggaaaaagt agtgattaaa tttcatggtc aagaacttat gatgagccga
     7621 ttttctaatc ccaagaccat tatgcgcttt ctaaaggata gcgatagttt agcctatatt
     7681 cctacaccta tgggcatgca ggagtttatc atccaaacga gccattatca agttgatagg
     7741 caaaagattg aactagatta tcaactacaa aatcaagagg gacatccttt tgccagctat
     7801 caattggaaa ttacttgggg ctaggctcat gtctttttca aatttagcta tctatcttct
     7861 tggatcggct tcctagtgtg gtagattagg ctaatttttg gtataataaa agttatggaa
     7921 atcgaaaaaa ccaatcgtat gaatgcgctc tttgaatttt atgcggcgct tttgacagat
     7981 aagcaaatga attatatcga gctctactac gctgatgatt acagccttgc tgaaattgcc
     8041 gaggagtttg gtgtcagtcg tcaggctgtc tatgacaata tcaagcgaac agaaaagatt
     8101 ctggaagatt atgagatgaa attgcacatg tactcggact atattgtccg cagtcagatt
     8161 tttgatcaga ttttggagcg ctatcccaag gatgactttc tgcaggagca gatagaaatt
     8221 ttaacaagca ttgataatag agaataagag gaagaaaaat ggcatttgaa agtttaacag
     8281 aacgtttgca gaacgtcttt aaaaatctac gtaaaaaagg aaaaatctct gaatctgatg
     8341 tccaagaggc aaccaaagaa attcgcttgg ccttgctcga ggccgacgtt gccttgcctg
     8401 ttgtaaagga ctttatcaag aaagttcgtg agcgtgcagt cgggcatgag gtcattgata
     8461 cacttaatcc tgcgcaacag attattaaaa tcgttgatga ggaactgaca gccgttttag
     8521 gttctgatac ggcagaaatt atcaagtcac ctaagattcc aaccatcatc atgatggttg
     8581 gtttacaagg ggctggtaaa acaacctttg ctggtaaatt ggccaacaaa ctcaagaaag
     8641 aagaaaatgc tcgtcctttg atgattgcgg cggatattta tcgtccagct gccattgacc
     8701 agcttaagac cttgggacaa cagattgatg tgcctgtctt tgcacttgga acagaagtac
     8761 cagctgttga gattgtacgt caaggtttgg agcaagccca aactaatcat aacgactatg
     8821 tcttgattga tactgcgggt cgtttgcaga ttgatgagct cctcatgaat gagcttcgtg
     8881 atgtgaaagc attggctcaa ccaaatgaaa tcttgcttgt cgttgatgct atgattggtc
     8941 aggaagcagc caatgttgcg cgtgagttta atgctcagtt ggaagtgact ggggtcatcc
     9001 ttaccaagat tgatggcgat actcgtggtg gtgctgctct gtctgttcgt cacattactg
     9061 gaaaaccaat caagttcact ggtacaggtg aaaagattac ggacattgaa accttccacc
     9121 cagaccgcat gtctagccgt atccttggta tgggggatat gctcactttg attgagaaag
     9181 cttctcagga atacgatgaa caaaaagccc ttgaaatggc tgagaagatg cgcgaaaaca
     9241 cctttgattt taatgatttc atcgatcaat tagatcaggt gcaaaatatg gggccgatgg
     9301 aagacttgct caagatgatt ccaggtatgg ccaacaatcc agcccttcaa aacatgaagg
     9361 tggatgaacg ccagattgct cgtaaacgtg ccattgtgtc ttcgatgaca cctgaagagc
     9421 gtgaaaaccc agatttgtta aatccaagcc gtcgccgtcg tattgctgct ggttctggaa
     9481 atacattcgt cgaagtcaat aaattcatca aggactttaa ccaggctaaa cagctcatgc
     9541 agggtgttat gtctggggat atgaataaaa tgatgaagca aatggggatt aatccaaata
     9601 accttcctaa aaatatgcca aatatgggag gaatggatat gtctgccctt gaaggaatga
     9661 tgggacaagg cggtatgcct gacttatcag ctctcggagg agcaggaatg ccagatatga
     9721 gccagatgtt tggtggcggt ttgaaaggta aaattggtga atttgccatg aaacagtcca
     9781 tgaaacgtat ggctaacaaa atgaagaaag cgaagaagaa acgcaagtaa gacaagagat
     9841 tgatgcaaat ctcatttgat gagaaaataa agtaaaaatt tctatgataa aacgtacagt
     9901 atcaaggttt tagaatatct gatattatac gttttttgat tttaataatt ttgttaagac
     9961 acttttatta tggtatacga aaaatccact cagctgtctg agtggattag gtgtatttag
    10021 actcttagtc tttattttcg tatggcaaga tcaagttcaa gatgattcct gtcatggctg
    10081 aaagggcagt acctgaaagt gtaactggac caagtttaag gatagctcct ccaagtccaa
    10141 gaaccaacat agcacttgcg atgatgaggt ttcgcatttg agcgaaatca acacgttctt
    10201 taatcaagac tttcaaacca ttgctggcga taaccccata gagaaggatt gacataccac
    10261 caagtacagc gtttggaata gttgaaatca aggcagtgaa tttaccaagg aagctgaggg
    10321 caatcgcgat gaaggcagcg ttacggataa ctgagacaga agcgatacga gtcataccga
    10381 taacccctgt attttctccg taagttgtat tggctggtcc accaaggaag gcagaaacag
    10441 aagttgcgat accgtcacca agaagagtac ggtgaagacc tggttctttt aagaattgac
    10501 gaccacagat ttgacccaaa acagtatggt ctccgatatg ttcagaaatt gttacgatag
    10561 cgattggcaa gatagcgatg gcttctggac caaagtaaag attgtactct ttaaaggcac
    10621 cacctgtgct aaatggcaag tagaaaccag gaatttcgaa ccagttggct ttaagaactg
    10681 gtgtaaagtc aaccaagcca agagttagtg cgaaaaggta accaccgata atggcaaaga
    10741 ggaatggaat gattcgtagg aagccttttc cttttgtatt gataaaggca gcaattagga
    10801 aagtaacaac ggctaccaga gcatttttcc aatttccgtc tgctacaaga cctgcattgg
    10861 taacagctga acctgcaagt ccaagaccga taacgatgat cataggaccg ataatgattg
    10921 gtggcaagag tttatcaatc cattttgttc ctacaaatcg gatgctggta gcaacaagga
    10981 catagaccaa accagtcaag ataacccctg tttgggcagc agatacatcc ccccccattt
    11041 ctttcatagc cagtgacata gctgtgataa aggcaaatga agaacctaga taaactggaa
    11101 ctttaaaacc agtagcaatc atgtagatga gtgttccaac acctgaagca aaaagggcaa
    11161 cagatacagg cattcccaaa atcaatggta ccaagatggt cgcaccaaac atggcgaaaa
    11221 cgtgttggaa actaaggaga attccttttc cagccgaagg acgttggtca acgtctagta
    11281 acaaatcaac agttgattct tgtttcatat aaacctcact tttgggcatc aaaaaagagc
    11341 ccattatttt acagcaatag gccctcagag taagacttct ttaaaattta gattttaaag
    11401 agttttaaat atttctgcgt cttcgtcacc tcacgggatg acattaaaaa cctttgctta
    11461 ggatagtata gcagaaaaaa atgattttgt aaatcatttt ttcccgagcc tagaaataaa
    11521 agagcgaggc tgattttgta aatcattttt tcccgagcct agaaataaaa gagcgaggct
    11581 gattttgtaa acatttgttt actaaaaaat ttaaagtggg cgtttatttg gcataccagc
    11641 cttacgcgga tatttatttg gtgtttcttt tttcttttct accactgtga tatagcgcgg
    11701 atctctattc ggtagggcgt agctgagatt gtcttcgacc ttactaaaaa ggagattgag
    11761 ggcattctta gcttctaata attcctcagg cgcattgctg gccttgagtg ccaatagttt
    11821 tccaccaacc ttaaggtagg gaatggtcaa ttcagatagg acctgcatac gggcaaccgc
    11881 acgagctgtt acaaaatcat attgagcacg gaagttcttg tcttgggcaa aatcttcggc
    11941 acgtccgtgg tagaaatgaa ctccgttcaa atccagttct tgagccaaga gttgtaggaa
    12001 gttgatgcgc ttattgagtg aatcaataat ggtcacatct aactccggat agagaatttt
    12061 cattggtaga ctaggaaatc ctgccccagc cccgatatca agaagtttga tagtttcatt
    12121 gggaatcaaa ccttgaagaa tgggtgcaat cgaatcgtaa aaatgtttga gataaacttc
    12181 ttccttgtcc gtaatcgccg tcaaattaat cttctcattc cactcgacca agagctcaaa
    12241 ataacgttca aattgttctt tttgctggtc cgaaagtgga agattctgct cggcaagcaa
    12301 gttgtaaaat gtttttggtt tcatagttat ttccttcttt agtatcatct tattttacca
    12361 caatcataga aaatttgata tactggtact aatctaaaag cagaaaggac ttatattatg
    12421 acttggatta ttcttggagt tatcgctctt attgttattt ttgtgattgt tagctataac
    12481 ggtttggtta aaaatcgtat gcaaaccaag gaggcttgga gtcagattga tgttcagttg
    12541 aaacgtcgaa atgacctctt gccaaacttg attgagactg taaaaggtta tgccaaatat
    12601 gaaggttcta cccttgaaaa ggtggcagaa ctacgtaacc aagtggcggc agcgacttca
    12661 ccagcagaag ctatgaaagc cagtgatgcc ctcactcgtc aggtttcagg tatttttgca
    12721 gttgcagaaa gctatccaga tttgaaagct agtgctaact ttgttaaatt gcaagaggag
    12781 ttgacaaaca cagaaaataa aatttcttac tctcgtcaac tctataacag tgttgtcagc
    12841 aactacaatg taaaattaga aactttcccg agcaatatta tcgctggaat gtttggattt
    12901 aaagcggcag atttccttca aacatctgaa gaggaaaagt cggttcctaa agttgatttt
    12961 agcggtttag gtgactaaga tgttgtttga tcaaattgca agcaataaac gaaaaacctg
    13021 gattttgttg ctggtatttt tcctactctt agctcttgtt ggttatgcgg ttggttatct
    13081 ctttataaga tctggacttg gtggtttggt tatcgcactg attatcggct ttatctacgc
    13141 tttgtctatg atttttcaat cgacagagat tgtcatgtcc atgaatggag cgcgtgaggt
    13201 ggatgagcaa acggcaccag acctctacca tgtagtggaa gatatggctc tggtcgctca
    13261 gattcctatg ccccgtgttt tcatcattga tgatccagcc ttaaatgcct ttgcgacagg
    13321 ttctaatcct caaaatgcgg ctgttgctgc gacttcaggt ctactagcta tcatgaatcg
    13381 tgaagaacta gaagctgtta tgggacatga agtcagtcat attcgtaatt atgatatccg
    13441 tatttcgact attgcagttg cccttgctag tgctatcacc atgctttcta gtatggcagg
    13501 tcgtatgatg tggtggggtg gagcaggtcg cagacgaagt gatgatgacc gagatggaaa
    13561 tggtcttgaa atcattatgc tagtggtttc cctactagct attgtactgg cacctctcgc
    13621 tgcaaccttg gttcagctcg ctatttctcg tcagagggaa tttctggcag atgcatctag
    13681 tgtcgagctg actcgcaatc cccagggaat gattaatgcc ctagataagt tggacaatag
    13741 caaacctatg agtcgccacg tcgatgatgc tagcagtgcc ctttatatca atgatcctaa
    13801 gaaaggtggg gggttccaaa aactctttta tacccaccca cctatctcag aacggattga
    13861 acgtttaaaa cagatgtaaa agaatccaga ggtcgtctct ggatttttgc tatgttgcaa
    13921 atttataaat cttctaaatt aactagcttc aaaccgtgtt ctgtcatgcg atagatgatc
    13981 gagcagactt cttttaagaa acgacggtca tgcgaaacag tgatgagacc gcctggatag
    14041 gttgcaaaga gttttctgat ttggggttga gaagtgggag aaaagtttcg tgtgggttca
    14101 tccagcagga gaaagtttgg tttgcgcaga actagatcca aaagcaggag ttttccctgt
    14161 tgtccgccag ataaggagcg aatttgatgc tgcatttctg gataactgaa attgagactg
    14221 gctaggtgag attggatttt ctgaagttcc tctttttccc cagttttgct gatataagct
    14281 attgaggata aatccaattg cagttttttg tggtaatctt gtggcataaa accaagtgaa
    14341 atctctcttt tatcattcag aagttgctgt aatttggcta acagagttga tttcccaaca
    14401 ccatttgggc cgatgatacc gattttttct tggccacgga cagttagttg cagttcctga
    14461 gccaaaacac ggtcgtcaat ggacaaattt tctttttcca gttggactaa gactttagaa
    14521 gctggtaatg gttggatgtc tgaaaagaaa agttggattt gttcctcttc aagtggcttt
    14581 tgagtcatgg actgagctgt cttttcgtag cgtttttctt gtgagaggac agttttcatc
    14641 tttttagcca ataggcgacc ggcagtacta tctttggtag ctcgaagcgc agtttctaca
    14701 ttttgcttaa ctctccgatg tttttccatg gttttatcgt aggctctttg gttgttagca
    14761 gcttgctgac tttgtttggc aaaattagcc tttctctgct cactatagct atcatagtct
    14821 aaatgctcta ctagcgtttc cgcttcttta cggtgtttga ccagtcgcaa gtgaacaata
    14881 gtgtctgccg tttcagaaag aaagtcttca tcatgggaaa tgaaaataac ggtttgcctg
    14941 gtcttttgaa tctggccttt tagccaatca actgtctcaa ggtctaggtc atttgaaggt
    15001 tcatctaaaa atagaatctc aaagggtttg gctaactcat ggataagctg aattttcaaa
    15061 gcttcgcccc ctgatagatt gccaatctct tggtcacttg cgaaacgatt gctatcaaaa
    15121 tgcaattcct ccgccaaacg atagaggata ctgtagtcta aatcaataga atctaaaaag
    15181 aagtagtcgt gtaaagtttt cttttttagg tcctcaggga ctttttgagg aatgtaggcc
    15241 agtgactgat aatcagactg gatgtctccc ttgatagtga aatcagacaa atcttccccc
    15301 attaaagttt taagtaaggt tgatttacca tttccttctt cgccaataat agctaccttt
    15361 tccccgtctt gtatggtcat gcttaggtca gagacaaggt ctcgtaaatc tttgttttgt
    15421 gtgatggtca ggtgattgat ttttatcata ctattgccct ttctagaatg tcgatagtgc
    15481 ataacaaaaa gctctacttt acctagtaga gcccaaagtc tatgtcaaaa aaactctatt
    15541 aacatgccag aaaaagagca taaaagagca cacaaaaaga gacaaaaaca agatctacta
    15601 aataaaggtt ctttatttga tagacttagt tgttcatgtc tcccttacct ccgagtatta
    15661 gtatctttat actatacttt taaggaaatt ttgtcaacag aaaactggaa attctatgct
    15721 ctaaaatcca aaaacaggtc catagagact tagtacgtgt ttgacatgct cgtaatggat
    15781 tttatcatag tttcgccaag cagtgcgtgc ttgatcgttt agttttaggc tacccagtcc
    15841 aatcagagga ctggtgggtt ggtaaaattt ctcaagatca attaagatac tgttgttcaa
    15901 cttttccgtt tttttgagct cttgcatagt agtgtttagc agctcttgta gtcgaatatc
    15961 atctgccgta ccctgtttac agttttggta gcttttattt aacttggata ggagttgaat
    16021 gagtttcttg tcttccatgt cttccatatg agcatcctcc ttgatctgat gtactctttc
    16081 cctatagtat agcactaaaa aataaaactg tcatagtaaa tatgttaaaa ttttgaattt
    16141 taattacaaa gtttggtgtg ctgatttgta gccttttcat ggtataatca agagagtaaa
    16201 tctttatgga ggaagtatga aattaaatat tcaagaaatt cgtaagcagt ctgaaggttt
    16261 gaactttgaa caaacgttag atttagttga tgacctgcgt gcacgtaatc aagaaatttt
    16321 agatgtaaaa gatatccttg cagttgggaa agtacaatat gaagaccgta tgtatttctt
    16381 agattatcaa ctatcttata ccattgttct tgcttcgagt cgcagtatgg agccagttga
    16441 gttagttgaa tcttatccag tcacggaagt tttcatggaa ggcgcaacta accagctaga
    16501 tcaagaagtt ttagatgatg acttggtctt gcccattgaa aatggggagc ttgaccttgc
    16561 tgagagtgta tcagacaata tcctgctaaa cattcctatc aaggtcttga cggctgaaga
    16621 agaagctggt caaggattta tctcaggaaa tgactggcaa atcatgacag aggaagaata
    16681 ccaagctcaa caagcagtaa agaaagaaga aaacagtcct tttgctggct tacaaggact
    16741 atttgacgga gatgaataat ggtcttgtca aaaaaacgag cacgaaaggt gctagaagaa
    16801 atcattgccc tcttcccaga tgccaagcct agtcttgatt ttaccaatca ttttgaactc
    16861 ctggttgcgg tcatgttatc agcccagacg acagatgcag cggtaaataa ggccacacca
    16921 ggtctctttg ttgcctttcc aacaccccaa gctatgtctg tagcgacaga gagtgagatt
    16981 gcttcacata tttctcgctt gggattgtat cggaataaag ctaaattcct taaaaaatgt
    17041 gcccaacagt tactagacga ttttgatggt caagtccctc agacacgtga agaattggag
    17101 agtttggcag gtgttggtcg caagacagcc aatgttgtca tgagtgtagg atttgggatt
    17161 ccagcctttg cagtggatac tcatgtggag cgtatttgca aacaccacga tattgtcaaa
    17221 aaatcagcga cgccacttga ggtggaaaag cgggtcatgg atatcttgcc gcctgagcag
    17281 tggttagctg cccatcaggc catgatttat tttggaagag ccatttgcca tccaaaaaat
    17341 ccagagtgtg accagtaccc acaattatat gattttagca atttgtaaga tgctacattg
    17401 aaactttttg cttgatttta agcatgcttt gtgctatagt aaatgataac taaatattcc
    17461 tttaaacctg tcccgtgagg caggcaagga gcgcgataaa gtagaagggt gaagtctata
    17521 ctgtttgcag tagggctcgc ttggctataa atttcaagtc tccttgttta aggagacttt
    17581 tctttttgga ggtttgtcat gaaaacaaaa gaagttgtag acgaattgac cgtcaaacga
    17641 gcgattacgc gtattactta tgagattatc gaacgcaaca aagatttgaa taagatcgtc
    17701 ttggctggta ttaaaactcg tggtgtcttt attgcccacc gaatccaaga acgtttgaag
    17761 cagttagaaa atctttcagt tcctgttgtg gaattggata ctaaaccttt ccgtgatgat
    17821 gttaaaagtg gagaagatac ttctttggtt tctgtcgatg tgacagaccg cgaagttatc
    17881 ttggtggatg atgtgctcta tacaggtcgt accatccgtg ctgctattga taatattgtc
    17941 ggtcatggtc gtcctgcgcg tgtgagttta gcagttctag tcgatcgtgg acatagagaa
    18001 ttgccaatcc gtccagatta cgttggaaaa aatatcccaa ccagtcgttc tgaagaaatc
    18061 atcgtagaga tgacagaact tgatgaccaa gacagagttc tgattactga agaagcttag
    18121 aaagttaaag gagtagccat gtcagaaaat caacaagcat tgaaccatgt ggtgtccatg
    18181 gaagacctca ctgtcgatca agtaatgaaa ttgatcaagc gaggaattga gtttaaaaat
    18241 ggagcccagc ttccctatga agaccatccg attgtttcca atctcttctt tgaggattct
    18301 acacggacac ataagtcctt tgaagtcgca gagattaaac ttggattgga acgacttgac
    18361 tttgatgtga agactagttc ggttaataag ggtgagacac tttatgacac cattttgact
    18421 ctgtctgctt taggagtgga tgtctgtgtg attcgccatc cagaggtcga ctactataga
    18481 gaattgattg ctagtccaac gattacgact tccatcatca atggtggaga tggttcgggc
    18541 caacacccta gccagagctt gcttgatttg atgaccattt atgaggaatt tggccacttt
    18601 gagggtctta aagttgctat tgcaggtgac ttggaccact cacgcgttgc caaatccaat
    18661 atgcagattt tgaaacgctt gggagctgaa ctctttttcg ctggacctga ggaatggaga
    18721 agtcaagagt ttgcagacta tggaaagttt gtaaccattg atgaaatcat tgatcaggtt
    18781 gatgtcatga tgtttctccg tgtgcaacac gaacgccatg atagtggagc tgtattttca
    18841 aaagaagact atcatgccca acatggcttg actcaagaac gttacgatcg tttgaaagaa
    18901 acagcaatcc tcatgcaccc agctccaatc aatcgtgatg tagaaatagc agaccacttg
    18961 gttgaagcac caaaatcacg gattgtccaa caaatgacca atggtgtctt tgttcgaatg
    19021 gcaatcttag aatccgtact agcgagtaga aacgccaact aaaacacaag acgttaaaag
    19081 acgccagtga gcgtccacga gaggtgaaaa tatgacaaaa agaattctag tattagaaga
    19141 tggcacagtt tttgaaggca aggccttcgg agcagatatt gatgtaacag gcgaaatcgt
    19201 ctttaataca gggatgaccg gctaccaaga atccattaca gaccagtctt ataatggaca
    19261 aatcttgacc tttacttatc ctttggtagg aaattatggt attaatcgtg atgattatga
    19321 atccattatt ccaacttgta agggagtcgt tgtttttgaa gaagcgcgta gagctagcaa
    19381 ctggcgcaac caaatgacct tggatgaatt tttgaaagcc aagaaaattc cagggatttc
    19441 aggaattgat acgcgtgctc ttaccaagat tatccgtaag catggtacta tgcgtgcaac
    19501 cttgacccat gttggggaca gtatggacca tgtgacggac cagctccaag caacagtttt
    19561 accgacagac aatatcaaac aggtttctac taaaacgtct tatccagctc caggagttgg
    19621 tttgagcgtg gtgctagtgg actttggtct caagcactca atcctacgtg aactttctaa
    19681 acgcaactgt aacgtgacag ttgttcctta ttcgacaacg gctgaagaaa ttctccatct
    19741 caatcctgat ggagttatgt tgtcaaatgg tccaggtaac ccagaagacg ttccacaagc
    19801 actcgacatg attcgcggtg tacaaggaaa aattccaatc tttggtattt gtatgggaca
    19861 ccaactcttt gcaatggcaa acggggctaa gacctataag atgaagtttg gccaccgtgg
    19921 attcaaccat gcggtacgtg aaatcgcaac aggacgagta gacttcacca gccagaacca
    19981 tggttatgca gtcagccgcg aggatttgcc agagcacttg attattaccc acgaagaaat
    20041 caatgacaag tcagtggaag gtgtgcgcca cagataccaa cctgctttct ctgttcaata
    20101 ccacccagat gcagctcctg ggccacacga cgctagctac ctatttgacg agtttatcga
    20161 gatgatggaa gtttttaaac aatcaaacta agaatgagta aaagctcgtc ggagaattta
    20221 tgtaactgaa catggacgga aagctcagaa tttagagaaa ccaacttgga ttgtcaatcc
    20281 ttccttgatt tcctaaaatt caatcgcttt ctagtcgtcc tttgtatctt atttaatgtc
    20341 gccctgagag gcgacgaata gaaaggagaa gatacattgt tcgcggaagt gaacacgccc
    20401 taagaactgt gtgaaaaaga taaacatcgt cttgacgctg aaggcgtctg cgccgagttt
    20461 cctattttca ctgtgttctt tacgggcttt gtatcataaa ctatgcctaa acgtactgat
    20521 attcaaaaaa ttatggtgat tggttctggt ccgattatta ttggtcaggc tgctgagttt
    20581 gactacgctg ggactcaggc ttgcttgtcg ttgaaagagg aaggttatga ggttgttttg
    20641 gttaactcaa atcctgcaac catcatgacg gacaaggaaa ttgctgacaa ggtttacatt
    20701 gaaccgatta cacttgagtt tgtgacacgt attcttcgta aggaacgtcc agatgccttg
    20761 ctaccaacac tcggtggtca gacaggtctc aacatggcca tggaattgtc taaaaatggt
    20821 atcttagatg agcttggcgt tgaacttctg ggtaccaaat tatctgccat tgaccaagcg
    20881 gaggaccgtg acctctttaa acaattgatg gaagagcttg aacaacccat tccagaatct
    20941 gaaattgtta acacagtaga agaagcagtt gcctttgcag cgacaattgg ctacccagtc
    21001 atcgttcgtc cagcctttac cctcggtggt actggtggtg gtatgtgtgc caacgagaaa
    21061 gaattgcgtg aaatcactga aaatggtttg aaattgtcac ctgttaccca atgtttgatt
    21121 gagcgttcga ttgccggttt caaggaaatt gaatacgaag tgatgcgtga ctcagctgac
    21181 aatgccttgg ttgtttgtaa catggaaaac tttgacccag ttgggattca cacgggggat
    21241 tccattgtat ttgcccctgc gcaaaccatg tcagactatg aaaaccaaat gcttcgtgat
    21301 gcgagcttga gcattattcg tgccctcaag attgaaggtg gatgtaatgt tcagctagct
    21361 cttgatccta acagcttcaa gtattatgtt atcgaagtaa accctcgtgt atcacgttcg
    21421 tcagcccttg cttctaaagc gacaggatat ccgattgcta agttggctgc caagattgca
    21481 gtaggtttga ccttggatga ggttataaac ccagttacag gttcaaccta tgccatgttt
    21541 gaaccagccc ttgactacgt agttgctaag attccacgtt tcccatttga caagtttgaa
    21601 aagggtgaac gccgtctcgg tacacaaatg aaggcgactg gagaagtcat ggcaatcggt
    21661 cgtaacatcg aggaatctct tctcaaggcc tgccgctccc ttgaaattgg ggtgcaccac
    21721 aatgaaatac ctgaacttgc agcagtttct gatgatgcct tgattgaaaa ggttgtcaaa
    21781 gcccaagatg accgtctctt ctacgtatca gaagcaattc gtcgtggcta cacacctgaa
    21841 gaaattgcag agcttacaaa aattgatatc ttctatcttg ataaactctt gcatatcttt
    21901 gaaattgagc aagaattggg tgctcatcca caagatctag aagttttgaa aacagccaaa
    21961 cttaatggtt tttcagaccg taagattgct gaactctggg gaacgactga tgatcaagtt
    22021 cgccaacttc gcttggaaaa caagattgtt ccagtttata agatggtaga cacttgtgcg
    22081 gcagagttcg actccgaaac gccatatttc tattcaacct atggttggga aaatgaatct
    22141 atcagatctg ataaagaatc tgtacttgtc ctaggttcag gtccaatccg tattggtcaa
    22201 ggggttgagt ttgactacgc aaccgttcac tctgttaagg ctatccaggc agctggttat
    22261 gaagctatca tcatgaactc aaacccagag accgtttcaa cagacttctc tgtatcagat
    22321 aagctttact ttgagccatt gacattcgaa gatgttatga acgtcattga cttggaacaa
    22381 ccaaagggag ttatcgttca gttcggtggt caaacagcca tcaaccttgc ggagccattg
    22441 gcaaaagcag gtgtgaccat ccttggtaca caggttgctg acctagatcg tgccgaagac
    22501 cgtgacctct tcgagcaagc tctcaaagaa ttggatattc cacagccacc aggacaaaca
    22561 gctaccaatg aagaagaagc agctcttgca gctcgcaaga ttggcttccc agttcttgtc
    22621 cgcccatctt atgtacttgg tggacgtgcc atggaaatcg ttgaaaacga agaagacctt
    22681 cgttcttaca tgcgaactgc tgttaaggct agtccagacc acccagttct tgtcgactct
    22741 tatatcgttg ggcaagagtg cgaagttgat gccatttcag atggtaaaaa tgtactcatt
    22801 cctggtatca tggagcatat cgaacgtgct ggtgtccact caggtgactc aatggctgtt
    22861 tacccaccac aaaccttgtc gcaaaaggtt caggagacca tcgcagacta caccaaacgc
    22921 ttagcaatcg gtcttcactg ccttggaatg atgaacatcc agtttgttat caaggatgaa
    22981 aaagtctacg ttattgaggt caatccacgt gccagccgta ctgttccatt cctatctaag
    23041 gtaaccaata ttcctatggc tcaagtagcg accaaactca ttcttggtca aagtttatca
    23101 gaacttggct accaaaatgg actttaccct gaaagcaccc gtgttcatat caaggcacct
    23161 gtcttctcct ttaccaaact agctaaggta gacagcttgc tcggtcctga aatgaagtca
    23221 acaggtgaag ttatgggttc tgatgctact ttggaaaaag ctctctataa agcctttgaa
    23281 gcttcttatc tacacttgcc aacttttggt aatgtcgtct ttaccatcgc tgatgatgcc
    23341 aaagaagaag ccttgaactt ggctcgtcgt ttccaaaaca ttggttatgg aatccttgcg
    23401 acagaaggga cagcagcctt ctttgctagc catggcttgc aagcccaacc tgttggtaag
    23461 attggtgatg acgataagga tatcccaagt tttgtacgca aaggaagaat tcaagctatc
    23521 attaacacag taggaacaaa acgaactgct gacgaagatg gtgagcaaat tcgtcgttca
    23581 gccattgaac acggggtgcc cctcttcaca gcgctagata cagctaatgc catgcttaag
    23641 gtacttgaaa gtcgtagctt tgttacagaa gcgatttaaa tagaaaaata agatatagca
    23701 gactgaattt agaacagtac acaggaatac taaaatattt ctagaaatta atttgaattt
    23761 tctaattgat ttgttcgcat cttatttcaa tctactatag aaaaaagtct ttaaaattat
    23821 aaaacgcatc atatcaaggt ttttcaaaaa ccttgatatg atgcgtttta ttgtgggaat
    23881 atgtatttca ttttctacta aaattatgtt tttgaataac ctctatctta gtagtttgta
    23941 taatccccct caatcagttt ttgcgataag ctttaatgct atgactatac cactcttgca
    24001 tttcttttga tggtggtgtc atataatcgc catacatctg ggttaaaaat tggtcatatt
    24061 ttttgggaac aggcaacata cggccctcaa actcagttaa aatcagttct ttaaaggtat
    24121 caactgggaa gatttctttc atcccttcct taccgatccc aactcctcct tcatattgag
    24181 gaatgttggt tacagcattt ttgactagtt gatcaatttt cttgtaaaag tagcgaggat
    24241 tgacaaatcg gagagcgtac cagctacata atctaagaaa atcttttagt ttgctatcac
    24301 cgtgaactgc tcgtgatttt ttgatgtaag ctagttgacg aagggccaca tacttatagc
    24361 tcttgtcgac aatgctcaag tctgtaaatt gatcaattgg gaagacatcg atgaaaaggc
    24421 tggtatcatg acgcttgtac ttaacatggt cttctataac agtagaagta tccaaaatcg
    24481 atgcgaaatt atggaagtac caagaagatg tatcgtagga aagaaccttg tagcgagggt
    24541 gattttcttc ttcaataatc ttcagtaaac gctcataatc ctcacgataa agggaaatat
    24601 caatatcatc atcccaagga atcatacctt tgtggcggat ggctccaagc atggttccat
    24661 aactgagaaa ataaggaata tcatgtttct tacaagtctc atcaatatag tccagcaggg
    24721 ctagttgaat ttctttaatt tctttttttt ctaaatattg catcctaatc ctccaattta
    24781 taagcgtgaa attcatgact gtagaagcgt ttttcttctg gtggtagggt catataatct
    24841 ccataaaatt gtgtcaaaat agtatcaaat ttttcaggtg caggaaggct taaattctca
    24901 aagggtaaat cgattgtttt atcaaaggta gcacttggga agacttcctt ttccttaaat
    24961 tttgaaggaa taaaagccat atactgccca ttttcacgac tatatttttg aatttctttc
    25021 tcgattttat ttgcaaaata acgaggagaa accagtcgaa ggagcaacca aaaggctgtt
    25081 cgtatccaat cttttaaaag gctatcctta tagacaatat ttttatgttt actgaaagac
    25141 agcagtttga agctttctag tttataacaa gtatcaatga ccttaggatc atcaaagcga
    25201 tccataggga aaatatcgat aaagatacca gactcatagg tttttgtatt tcgagtatca
    25261 ataattttag tcgtactgtc ggttatcttg ataaagttgt taaagtagtt cttatcagtt
    25321 tctaaggata ggagcttata cttgcttttt tccttttgaa aaatgttaat aaatcgttgg
    25381 tagtcttctc taggcatgga taaatcaata tcgtcgtccc aagggataaa gccctcatgt
    25441 cgaaccgccc caatcagagt accgtagtta ataatatagt tgatattgtg ctttttacag
    25501 agagtatcaa tataattcaa aatttctaat tcaatttgtt tggcatcttc aacggttagt
    25561 tgtttcattt taaactccta agatttttta aatttatttt ttaaggctag gacatggttt
    25621 aaaaattcat agaaaatgct atcttttgtg aagacaagta gactaatata agagatagct
    25681 gatagcaaga caatcaaacc agtattaatc aaaaatggca aattaatgac catatccaca
    25741 ggatacacga aattaatcag gaaataaatt gctacaaagg aaagtgaaaa gagagagtat
    25801 cgaacagtat agctaaagat atgtcccaag tggatgagtt gttttctatg gatgaaaatg
    25861 atatagaaaa caagtagaga agcctctgat aacatagttg tcagtaagta gtattcggga
    25921 gccacgatat ggttgaaaaa gaggagacta ttcaagccca aattgagtag cccagcaaag
    25981 actgtataga ctgtgatacg tttttcatag ccattggtaa agagaatttg ggaaccaaga
    26041 atggtatcta aggccaggat aatcgtacga aaagcgaaga gagaggtcaa gatgtcgcct
    26101 ccgatatatt tttcactacc gtaaagtagg atggcatttg gtcctaaaac catgagtcca
    26161 aaactcagtg gaatgataaa gaagttaaag attcgactac ctctattaac cagagaaaca
    26221 taggcttctt tgtctccttt ccccagatag taactgagac gaggcacact cactccaatt
    26281 gcacctgtta caaccccagc tataacggtc acaattcgct gagctatggt atagtaacta
    26341 acgttgacat caatccctgt tttaacgagg aagaggcgat ctaaaaaagt gaagagcata
    26401 ttggcattgg caaagactaa catggctgtc agagggagaa agagtggttt aaaatcactt
    26461 aggtgaatct taacaagttt gatgtctctt ttaatccaaa aataactaat caggtagtta
    26521 atcagcgtcg ataaactcat cacaagtgta tagacaacaa tatcgtgttc atttttaaca
    26581 aataagaaaa tagagaccag catcaggata cggatgaagg cagttttgta aaagagaaaa
    26641 ctgtaatttt ccagagcttc attgacccat tcgattgaaa aaatctgggc aatgagttga
    26701 atccccataa caaggtagac ctttttgacg attggattat cagtaaagaa gagaggatag
    26761 gctaggatat agacagcagt ggtcaaaatc gtacaagcga tgcacaaata aaaaagacta
    26821 gaaaaggttc tgttaagatc ttttttgtta tccttgacat tactgatagc ccttaaaccg
    26881 tagttataga caccataagt tgcaaagggc aagaaaaatg acaaaatagt gtcgactgag
    26941 ttgaagtaac catagtcagt tcggtccaag acacgcgcga cataggttcc agttaggatg
    27001 ggaaaaataa tattcaagac acgaattccc atgtaagata gagcatttaa ttttatactt
    27061 ttcattcaat ttacctcgtt tttcattata tcataaagtt agctaataag aaatgaaggg
    27121 cagtaagtca agtaatcact ttgaagtttc aaatcttaag ttttaagttt tctttaagga
    27181 aagtatatta ttctgaagga ctctaaaatt tcgcagccat ttattagtaa ttgctacaga
    27241 attcctagtc attactagaa atggactagt ttctttgaat aatagaactg cataattctc
    27301 ctattctaga aggggaggac cagtatttct tttatgatag gactagattg tggtataata
    27361 gagagaataa gtttttttag taagacaaag gagaaaatag atgatttatg caggaattct
    27421 tgccggtgga actggcacac gcatggggat cagtaacttg ccaaaacaat ttttagagct
    27481 aggtgatcga cctattttga ttcatacaat tgaaaaattt gtcttggagc caagtattga
    27541 aaaaattgta gttggtgttc atggagactg ggtttctcat gcagaagatc ttgtagataa
    27601 atatcttcct ctttataagg aacgtatcat cattacaaag ggtggtgctg accgcaatac
    27661 aagtattaag aaaatcattg aagccattga tgcttatcgt ccgcttactc cagaggatat
    27721 cgttgttacc cacgattctg ttcgtccatt tattacactt cgcatgattc aggacagtat
    27781 ccaacttgcc caaaatcatg acgcagtgga cacagtggta gaagcggttg atactatcgt
    27841 tgaaagtacc aatggtcaat ttattacaga tattccaaat cgtgctcacc tttatcaagg
    27901 acaaacacct caaacattcc gttgcaagga cttcatggac ctttatggat ctctttctga
    27961 tgaagagaag gaaatcttga cagatgcatg taaaatcttt gtgatcaaag gaaaagatgt
    28021 ggccttggcc aaaggtgaat actcaaatct gaagattaca accgtaacag atttgaagat
    28081 tgcaaaaagt atgattgaga aagactagta aaatgattaa tcaaatttat caactaacta
    28141 agcctaagtt tatcaatgtc aaatatcagg aagaggctat tgaccaagag aatcatatcc
    28201 ttatccgtcc caactacatg gctgtctgtc atgcggatca gcgttactat cagggaaaac
    28261 gtgatcccaa gattttgaat aaaaagcttc caatggcaat gattcacgag tcatgtggaa
    28321 ccgtcatttc tgacccgacc ggaacctacg aggttggtca aaaagttgtc atgattccca
    28381 atcagtctcc tatgcagagt gatgaagaat tctatgaaaa ctacatgaca gggacccatt
    28441 tcttgtctag tggatttgat ggctttatga gagagtttgt ttctctccct aaagatcgtg
    28501 tggtggctta tgatgctatt gaagatacgg ttgcagccat tacagagttt gtcagtgtgg
    28561 gcatgcacgc tatgaatcgt ctattgactc ttgctcatag caagcgggag cggatcgccg
    28621 ttattggaga tggaagttta gcttttgtgg ttgccaatat tatcaactat actttgccag
    28681 aagcagagat tgtggttatt ggtcgtcatt gggaaaagtt ggaactcttc tcatttgcca
    28741 aagaatgcta tattacggat aatattcctg aagagttggc ctttgaccat gcttttgaat
    28801 gttgtggtgg tgatggtact ggaccagcta ttaatgactt gattcgctac attcgtcctc
    28861 agggaacgat tctcatgatg ggagttagcg aatataaagt caatctcaat actcgcgatg
    28921 ccttagaaaa gggcttgatt ttggttgggt catctcgttc tggtcgcatt gattttaaaa
    28981 atgctatcca aatgatggaa gtcaagaaat ttgccaatcg tcttaaaaat atcctttatc
    29041 tagaagaacc tgtaagagaa attaaagata ttcatcgtgt ctttgcaacc gatttaaaca
    29101 cagcctttaa aacagtgttt aagtgggaag tataagtact ggaggttaat tgtggagaaa
    29161 atcattaaag aaaaaatttc ttccttactt agtcaagaag aggaagtcct cagtgttgaa
    29221 caactgggtg gaatgaccaa tcaaaactat ttggccaaaa caacaaataa gcaatacatt
    29281 gttaaattct ttggtaaagg gacagaaaag cttatcaatc gacaagatga aaagtacaat
    29341 cttgaactac taaaggattt aggcttagat gtaaaaaatt atctttttga tattgaagct
    29401 ggtatcaaag taaatgagta tatcgaatct gcgattacgc ttgattcaac gtcaatcaag
    29461 accaagttcg acaaaattgc tccaatatta caaactattc atacgtctgc taaggaatta
    29521 agaggagaat ttgctccttt tgaagaaatc aaaaaatacg aatccttgat tgaagaacaa
    29581 attccttatg ccaactatga atctgttaga aatgcagtct tctccttaga gaaaagactg
    29641 gctgacttag gtgttgacag aaaatcttgt catatcgatt tggtgcctga aaactttatc
    29701 gaatcacctc aaggacgact ttatttgatt gactgggaat attcatcaat gaatgatcca
    29761 atgtgggatt tggctgccct ctttttagag tctgaattca cttcccaaga ggaagaaact
    29821 ttcttatctc actatgagag tgaccaaaca ccggtttctc atgaaaagat tgctatttat
    29881 aaaattttac aagatactat ttggagtcta tggactgtct ataaggaaga gcaaggtgaa
    29941 gattttggtg actatggtgt gaatcgttac caaagagctg ttaaaggttt ggcttcttat
    30001 ggaggttcag atgaaaagta aaaacggagt tccttttggc cttctctcag gtattttctg
    30061 gggcttgggt ctaacggtta gtgcttatat cttttcgatt tttacagatt tgtcaccctt
    30121 tgtggtggct gcagctcatg attttttgag catctttatc ttactagctt ttctcttggt
    30181 aaaagaaggg aaagttcgcc tctcaatttt cttaaatatt cgcaatgtca gtgttatcat
    30241 cggagccttg ctagcaggcc ctatcggtat gcaggccaat ctttatgcag ttaagtatat
    30301 cggaagttct ttagcttcat ctgtatcggc tatttaccct gcgatttcag ttctattggc
    30361 tttcttcttt ttgaagcaca agatttcgaa aaatactgta tttgggattg tcttgattat
    30421 tggagggatt attgcccaga cctataaagt tgaacaggtt aattctttct acattgggat
    30481 tctttgtgct ttggtttgtg ctattgcatg gggaagtgag agtgttctta gctcttttgc
    30541 catggaaagt gaattgagtg aaatcgaagc cctcttaatc cgtcaagtaa cttcgttctt
    30601 gtcctatctt gtgattgtgc tcttctctca tcagtcattt actgcagtag ccaatggaca
    30661 attgctaggt ctcatgattg tttttgcagc ctttgatatg atttcctact tggcttatta
    30721 tatcgctatc aatcgcttgc aaccagccaa ggctacaggc ttgaacgtga gctatgtagt
    30781 atggacggtc ttgtttgcag ttgttttctt gggtgcaccg ctagatatgc tgaccattat
    30841 gacgtcactt gtcgtcattg ctggagttta tattattatt aaagaataaa ggagattcgt
    30901 gtgaaagcca tcatcttagc agcgggattg ggaactcgct tgcgtcctat gactgaaaat
    30961 acccctaaag ccttggttca ggttaatcaa aaacctttga ttgagtacca aattgagttt
    31021 ctcaaagaaa aaggaatcaa tgacatcatc atcattgttg gttatcttaa agaacaattc
    31081 gattacttga aagagaaata cggtgttcgt ctcgttttca atgataaata cgctgactac
    31141 aataactttt actctctcta tcttgtaaaa gaagaattag ccaatagtta tgttatcgat
    31201 gccgataact atctctttaa aaatatgttc cgcaatgatt tgacacgttc tacttatttt
    31261 agtgtctatc gtgaagattg taccaacgaa tggttcttgg tctatggaga tgactacaag
    31321 gttcaaaaca ttattgttga tagcaaggca ggtcgcatcc ttagtggtgt atccttctgg
    31381 gatgctccaa cagcagaaaa aattgttagc tttatcgata aggcttatgc aagcggcgaa
    31441 tttgttgatc tctattggga caatatggtt aaggataaca tcaaagagct agatgtctat
    31501 gttgaagaat tagaaggcaa tagcatttat gagattgata gtgtccaaga ctatcataaa
    31561 ttagaagaaa ttcttaaaaa cgaaaattaa aagcttccaa catctgacaa aatagtcgga
    31621 tgtttttttg attttttacg aacttttacg aatagataga tgagtagaaa aagaaatgga
    31681 gttatttatg aaaatcacaa actatgaaat ctataagtta aaaaaatcag gtttgaccaa
    31741 tcaacagatt ttgaaagttc tagaatacgg tgaaaatgtt gatcaggagc ttttgttggg
    31801 tgatattgca gatatatcag gttgccgtaa tccagccgtt tttatggaac gttattttca
    31861 gatagacgat gcgcatttgt cgaaagagtt tcaaaaattt ccatctttct ctattttaga
    31921 tgactgttat ccttgggatt tgagtgaaat atatgatgcg cctgtacttt tattttacaa
    31981 gggaaatctt gacctcctga aattcccgaa ggtagcggtc gtgggcagtc gtgcttgtag
    32041 caaacaggga gctaaatcag ttgaaaaagt cattcaaggc ttggaaaatg aactggttat
    32101 tgtcagtggt ctggccaagg gcattgacac agcagctcat atggcagctc ttcagaatgg
    32161 cggaaaaacc attgcagtga ttggaacagg actggatgtg ttttatccta aagccaataa
    32221 acgcttgcaa gactacatcg gcaatgacca tctggttcta agtgaatatg gacctggcga
    32281 acaacctctg aaatttcatt ttcctgcccg taatcgcatc attgctggac tttgtcgtgg
    32341 tgtgattgta gcagaggcta agatgcgttc aggtagtctc attacgtgtg agcgagcaat
    32401 ggaagaagga cgcgatgtct ttgctattcc tggtagcatt ttagatggac tatcagacgg
    32461 ttgccatcat ttgattcaag aaggagcaaa attggtcacc agtgggcaag atgttcttgc
    32521 ggaatttgaa ttttaaaaat gacctaagct agaattctaa gaaaaaatca attttaagag
    32581 aaaatgaacc caacatttcc ataataaaac gcatattagc aagtttttaa cacttgataa
    32641 tatgcgtttt ttctaagtgg attagtagag tagaggattt ttctcatata atactcttcg
    32701 aaaatctctt caaactacgt cagcttccat ctgcaacctc aaaacagtat tttgagctga
    32761 cttcgtcagt cttatctaca acctcaaagc agtgctttga gcaacctgtg gctagcttcc
    32821 tagtttgcgc tttgattttc attgagtata agggaaagta tagtgaattg aaataagatg
    32881 tgaacaactc tatcaggaaa gtcaaattaa tttatagaaa tattttagca gccaaggtgc
    32941 actgttatag attcaataca ctataattta gtgtaattga gaaaggagaa atgattgtga
    33001 ttgatgttgg ctaggttatg ttcaatgatt cctaccgtct caaatcttgt cagtaaggaa
    33061 aaataaattc ttcaaaagta gagattacaa ggcttgttta agaaagaatt caaagacctt
    33121 gacaaataaa aataaaatgg ttattataaa aaatggtctg aaatagatga tgatactttt
    33181 cgaaaatctt tttacgtcag ctcagctttg ccttgctgtg ttttgagcaa gctacggtta
    33241 gcttccgagt ttgattttca tttactagaa atgaaactga tgagagatat cagtagacat
    33301 ttgagtcagg atattatgga aaatgataaa aagagctcgt gagattggca tatcagacta
    33361 ctaaagtatt gagtttgtta ggattttagc gactagttag ctgggaaagg aagatatttg
    33421 tgacaaataa taaactgtat tcgttgatag aatttagaaa taaaatatat gaagaattag
    33481 aactttccag aagtgattta gcgattttac tatgtgccat gcttatcgcc tctatcggat
    33541 taaatatgga ttcgactccc gtgattattg gagccatgtt aatctctcct ttgatgacac
    33601 ctattctggg agtggggctc tctctagcta tatttgattt taaattgtta agaaaatctt
    33661 ttaaaatatt agctattcaa attcttgcca gtttaatagc ttcaacactt tatttttatc
    33721 tttctcccat ttcgtatgct agttcggaaa ttgttgctag aacctctccg actatttggg
    33781 atgttctcat tgcttttgta ggagggatag caggtattat tggtgctagg aaaaaagaga
    33841 ccaataatat tgttcctggt gttgctattg caaccgcctt gatgcctcct ctttgtacag
    33901 taggttatgc tattgcttct gctaatctaa aatttatcat aggctcctct tacctattcc
    33961 tcatcaattg tagctttatt gtcattgcga cttatatagg tgttaggttg atgatggtta
    34021 agaaacatta ttttaaagat aatgaagaag actctaaaat gcgtaggatt ttgcttctag
    34081 ttgctgtttt gctgatgatt ccgagtttca tctctgcaac gactttagtg agagaaacgt
    34141 tgaaaaaaga gtcccttaag aaatttatat cagagcagtt tcaggggcat aatattttga
    34201 aaaaaaccta ttctaaaaag actcataccc taaagctaac catttcagga aattatttga
    34261 cagaagaaga actcgatatg atttcaagta agagaggtga ctatggttta agtgatgttt
    34321 ctgttcaagt ttcacaattg tctgattcag aacaacttag taaggaagaa ctggtggagt
    34381 atttcttcca gtatatcaag gataaggaag caaaagaaaa ggaaaaagct aataagtttt
    34441 atacagagtc tgaggagcaa taatttcttg agaatagctg gtttctctcg tgagtcttct
    34501 atgtatatca aaggaagact gaggttttaa gtataaaact tttcttctat tatagtagct
    34561 aagtcttgac agggttcaaa aaatggttta cactttataa agtttattac tttgaaaagg
    34621 tgtgatactg tggctacggc aacaaaaaag aaaaaatcaa cagttaaaaa aaatctagtc
    34681 atcgtggagt cgcctgctaa ggccaagacg attgaaaaat atctaggcag aaactacaag
    34741 gttttagcca gtgtcgggca tatccgtgat ttgaagaaat ccagtatgtc cgtcgatatt
    34801 gaaaataatt atgaaccgca atatatcaat atccgaggaa aaggccctct tatcaatgac
    34861 ttgaaaaaag aagctaaaaa agctaataaa gtttttctcg cgagtgaccc ggaccgtgaa
    34921 ggagaagcga tttcttggca tttggcccat attctcaact tggatgaaaa tgatgccaac
    34981 cgtgtggtct tcaatgaaat caccaaggat gcagtcaaaa atgcttttaa agaacctcgt
    35041 aagatcgata tggacttggt cgatgcccaa caagctcgtc ggatcttgga tcgcttggta
    35101 gggtattcga tttcgcctat tttgtggaag aaggtcaaga agggcttgtc agcaggtcgc
    35161 gttcagtcca ttgcccttaa actcatcatt gaccgtgaaa atgaaatcaa tgccttccag
    35221 ccagaagaat actggacagt tgatgctgtc tttaaaaagg gaaccaaaca atttcatgct
    35281 tccttctatg gagtagatgg taaaaagatg aaactgacca gcaatgacga agtcaaggaa
    35341 gtcttgtctc gtctgactag taaagacttt tcagtagatc aggtggataa gaaagagcgc
    35401 aagcgcaatg ctcctttacc ctataccact tcatctatgc agatggatgc tgccaataaa
    35461 atcaatttcc gtactcgaaa aaccatgatg gttgcccaac agctctatga aggaattaat
    35521 attggttctg gtgttcaagg tttgattacc tatatgcgta ccgattcgac tcgtatcagt
    35581 cctgtagcgc aaaatgaggc ggcaagcttc attacggatc gttttggtag caagtattct
    35641 aagcacggta gcaaggtcaa aaacgcatca ggtgctcagg atgcccatga ggctattcgt
    35701 ccgtcaagtg tctttaatac accagaaagc atcgctaagt atctggacaa ggatcagctc
    35761 aagctatata cccttatctg gaatcgtttt gtggctagcc agatgacagc ggccgttttt
    35821 gataccatgg ctgttaaatt gtctcaaaat ggagttcaat ttgctgccaa tggtagtcag
    35881 gttaagtttg atggttatct tgccatttat aatgattctg acaagaataa gatgttaccg
    35941 gacatggttg ttggagatgt ggtcaaacag gtcaatagca aaccagagca acatttcacc
    36001 caaccgcctg cccgttattc tgaagcaaca ctgattaaaa ccttagagga aaatggggtt
    36061 ggacgtccat caacctatgc gccaaccatt gaaaccattc agaaacgtta ttatgttcgc
    36121 ctggcagcca aacgttttga accgacagag ttgggagaaa ttgtcaataa gctcatcgtt
    36181 gaatatttcc cagatatcgt aaacgtgacc ttcacagctg aaatggaagg taaactggat
    36241 gatgtcgaag ttggaaaaga gcagtggcga cgggtcattg atgcttttta caaaccattc
    36301 tctaaagaag ttgccaaggc tgaagaagaa atggaaaaaa tccagattaa ggatgaacca
    36361 gctggatttg actgtgaagt gtgtggcagt ccaatggtca ttaaacttgg tcgttttggt
    36421 aaattctacg cttgtagcaa tttcccagat tgccgtcata cccaagcaat cgtgaaagag
    36481 attggtgttg agtgtccaag ctgtcatcag ggacaaatta ttgagcgaaa aaccaagcgt
    36541 aatcgcctat tctatggttg caatcgctat ccagaatgtg aatttacctc ttgggacaag
    36601 cctgttggtc gtgactgtcc aaaatgtggc aacttcctca tggagaaaaa agtccgtggt
    36661 ggtggcaagc aggttgtttg tagcaaaggc gactacgagg aagaaaagat taaataagag
    36721 gaggggcccg aaagtaaatt tcaggctcct tttggttaga acttgacaaa atacatcatt
    36781 ttatgcgaaa ctagaagaag attattttat actcaatgag aatcaaagag caaattagaa
    36841 agctagtcgc aggttgctca aagcactact ttgaggttga agatggaagc tgacctggtt
    36901 tgaagagatt ttcgaagagt attaactagg agaagttatg cgtattatct atctaattat
    36961 tggtttttta tcgctgacct tggctattgt tggggttgtt ttacccttgt tgcctacaac
    37021 acctttcctt ttgttgtcta ttgcttgttt ctccagaagt tccaagcgat tcgaagattg
    37081 gctttatcat accaagctct atcaagcata tgtagctgat tttcgtgaga ccaagtctat
    37141 tgcgcgtgaa cgaaagaaaa aaatcatcgt ctctatctac gtcttgatgg gaatttctat
    37201 ttattttgca cctcttttac cagtcaaaat cggtctgggt gctttgacca tctttattac
    37261 ttattatctc ttcaaggtca ttccagacaa agaatagtta aaacagtagt tatttgcctt
    37321 gataaaattg aaagcatatt cataacaata tgatataata aaattgaagt aatattcaag
    37381 gagaatcaaa tgatttacga attttgtgct gaaaatgtga ctttacttga aaaagcgatg
    37441 caggctggag ctcgtcggat tgaactctgt gataatctag cagttggtgg gacaacaccc
    37501 agctatggag tgactaaggc agcggttgaa ctggcagcta actacgatac aaccatcatg
    37561 accatgattc ggccacgtgg tggtgacttt gtctataatg acctagaaat tgctatcatg
    37621 ctagaagaca ttcgtttgac tgctcaggct ggaagtcaag gggttgtatt tggagcttta
    37681 actgctgata aaaagttgga taagcctaat ctggaaaagt taattgctgc atcaaaagga
    37741 atggaaattg tctttcacat ggcctttgat gaactaagtg atgaagatca accggaagct
    37801 attgactggc tcagtcaagc cggtgtcact cgtatcctaa ctcgtgctgg tgtgtctggc
    37861 gactccttag aaaaacgttt tgttcactat cacagaattt tggagtacgc taaaggtaaa
    37921 attgaaattc taccaggtgg ggggattgac cttgaaaacc gtcaaacctt tatcgaccag
    37981 gtgggggtaa cacaattgca tggtactaag gttgtttttt aaaaaataga aaggaactgc
    38041 tagctttggg tagcagtttt cacttatgtt tgaaattttt aaatcctatc aatttaatca
    38101 agaaaaggct catgattatg gttttataga aaatagcgaa gtctggacat atagttgcca
    38161 gattttgcaa ggtgactttg tcatgactgt gtccatcact gctgataatg tgaactttca
    38221 agtctttgac caagagactg gtgacctcta tcctcacgtt tatatggaaa gcatgagggg
    38281 aagttttgtc ggaaatgtcc gtgaggcttg tctggagatt ctttaccaga ttcggaaggc
    38341 ttgttttgat gtgcaagatt ttatctgtca tcagactaag cgtatcatga ctcaagttca
    38401 ggaaaagtat ggaaaccagt tggagtatct gtgggaaaaa tcgcctgata cagctgtatt
    38461 gcgccatgaa ggcaatcaaa agtggtatgc cgtcttgatg aaaatctctt ggaataagct
    38521 ggaaaagggc agagaaggac aagtggaagc agtcaacctc aagcatgacc aagtagctaa
    38581 tttgctttca caaaagggga tttatccagc cttccatatg agcaagcgct actggattag
    38641 tgtgtccctt gatgatactt tatcagatga agaagtactg gaattgatag aaaaaagttg
    38701 gaacttaacc tctaaaaaat gaaatatttt aataattttc atgaactttc aattagctaa
    38761 atattcttta ctgaagagat ttttagaaaa tataggattt accacactag aggaatatgg
    38821 tgccatcttc aaatacctga ttgagaatgt caagacggat cgtcagatca tctattcgcc
    38881 tcactgtcat gatgacctcg gaatggcagt ggcaaatagc cttgctgctg tcaagaatgg
    38941 tgcaggacgt gttgaaggga ctatcaatgg tattagggag cgagctgaaa atgctgcttt
    39001 ggaagaaatt gcagtggctc tcaatattcg ccaagattac taccaagtag aaaccagtat
    39061 tgtcctaaat gagaccatca atacgtcaga aatggtttct cgcttctctg gtattccagt
    39121 tcctaaaaac aaagccgtcg ttggtggcaa taccttctcc cacgaatctg gtattcacca
    39181 agatggagtc cttaaaaatc ctctcactta tgagatcatc acacctgaat tggttggtgt
    39241 taagattctg cttggaaaat tatctggtcg ccatgctttt gttgagaaac tgagagaatt
    39301 ggccctagat tttacagaag aggatatcaa accactcttt gctaagttca aggcactggt
    39361 cgataagaag caagaaatca cagatgcaga tattcgagct ttggtagctg gaaccatggt
    39421 tgaaaatcca gaaggcttcc actttgatga tttacaactt caaactcatg cagataatga
    39481 cattgaagcg ctcgttagcc tagccaatat ggatggtgag aaagtcgaat ttaatgcgac
    39541 agggcaaggt tccgttgaag caatctttaa tgctatcgat aagttcttta accaatctgt
    39601 tcgtttggtg tcctacacta tcgatgcggt aacagatgga atcgataccc aggatcgggt
    39661 tttggtcact gttgaaaaca gagatacaga aaccatcttt aatgcagcag ggcttgattt
    39721 tgatgtgttg aaggcttctg ctattgtcta tataaacgct aatacctttg ttcaaaaaga
    39781 gaatgcaggt gagatgggac gcagtgtttc ttaccacgat atgcctagtg tgtaaaggag
    39841 aaggctatgg caaagaaaat agtagctcta gcaggagacg gaattggccc agaaatcatg
    39901 gaggttggtt tagaagttct ggaggctcta gctgaaaaaa caggttttga ctatgagatt
    39961 gacagacgac cgttcggagg tgcagatatt gatgcagcat gacctccctt acctgatgaa
    40021 acccttaagg caagtaggga agcagatgct atcctactag tagctatcgg tagtcctcag
    40081 tatgatggag cagtggttcg ccctgaacaa ggcctgatgg ctctccgtaa ggaactcaat
    40141 ctttacgcta atattcgtcc tgtaaaaatc tttgacagtc tcaagcattt gtcactactc
    40201 aaactggaac gaattgctgg tgtagacttt gtcgtggtgc gtgaattgac aggcgggatt
    40261 tactttggag atcatattct tgaagagcgc aatgcgcgtg atatcaacga ctatagctat
    40321 gaggaagtgg agcggattat tcgcaaagcc tttgaaattg caagaaatcg cagaaaaatc
    40381 gttactagta tcgataagca aaatgttcta gcgacctcaa aactctggcg gaaagtagct
    40441 gaggaagtcg cacaggattt cccagatgta accttggaac atcagctggt agactcagct
    40501 gctatgctta tgattaccaa tcctgctaag tttgatgtta ttgtaacgga gaatcttttt
    40561 ggagatattt tatctgatga atcaagcgtc ttatctggta cacttggggt tatgccatca
    40621 gccagtcatt ctgaaaatgg accaagtctc tatgaaccta ttcacagttc agcacctgat
    40681 attgcaggtc aaggaattgc caatcctatt tccatgattt tatcagtttc catgatgttg
    40741 agagatagtt tcggacgtta tgaggatgca gagcgtatca aacgtgctgt tgagacaagt
    40801 ctggcggcag gaattttaac gagagatata ggaggtcagg cttcaacaaa ggaaatgacg
    40861 gaagctatta ttgcaaggtt atgaagttag acgaaaaaat tactctagtc cttttgattt
    40921 ggaatgtcat cattttcttg atttatggta ttgacaaatc taaggcaagg agaagagttt
    40981 ggcgcatccc tgagaaaatc ttacttattt tagcctttac ttttggtggt tttggtgcct
    41041 ggctagcagg aatcatcttt caccacaaga ctcgaaaatg gtactttaaa atagtttggt
    41101 ttcttgggat ggtgaccaca ctagtagcct tatattttat ttggaggtaa tggatggcag
    41161 ggtcttcgag ggaatacgct gcttgggctc tagcggacta tggttttaag gtcgtgattg
    41221 caggatcttt cggtgacatt cattacaata atgaactcaa taatggcatg ttgccaatcg
    41281 ttcagcctag agaggttaga gagaaactag cccagctaaa accaaccgac caggtaactg
    41341 tggacttgga acaacaaaaa atcatctcac cagttgaaga attcaccttc gagatagata
    41401 gcgagtggaa acataaactc ctaaatagtt tggatgatat cggtattacc ttgcagtatg
    41461 aagagttgat tgctgcttat gaaaaacaac gaccagccta ctggcaggat tagaaaaaat
    41521 agaaaaggag atatagtaaa ctgaaataag atgtaaacaa atgaattgga gcttaacatc
    41581 catttccagc aattttttag aaactacagt ggactattct ggattcaaca cattataaaa
    41641 ttatgacaaa acacattcac aagaaggcta cgacatttta aaaggtgagg gcggatgtat
    41701 cgtttgccct actaaagttg gttacattat catgaccagt gacaaggcag gacttgagcg
    41761 taagttcgca gccaaagaac gtaagcgtaa caaaccaggt gttgttctct gcggtagcat
    41821 ggatgaactt tgcgctttag cgcaactcaa cccagaaatt gaagcattct actaaaaaca
    41881 ttgggatgaa gatattcttc ttggttgtat ccttccttgg aaaccagaag cctttgaaaa
    41941 actcaaagca tacggggatg gccgtgaaga acttatgact gatgtacgtg gtactagctg
    42001 ttttgttatc aagtttggaa aagcaggtga acaattggct gccaagcttt gggaagaagg
    42061 taaaatggtc tacgcctcat ctgcttcaat gacaaaacga ttgaaactcg ctatgagcaa
    42121 ggtgtaatgg tgtctatggt cgataaggac ggcaaactca tcccagaaca aggaggagca
    42181 cgttcaactt caccagctcc agttgtgatc cgtaaagggc ttgacattga tatagtaaaa
    42241 tgaagtaaga gcaggacaaa ttaatcagga cagtcaaatc gatttctaac aatgttttag
    42301 aagtagaggt gtactattct agtttcaatc cactataaaa tcatgatgca cctgtcagat
    42361 acttttaact catgggacta ccgtcaggtt gagtattatt aggatagaga agaagtctag
    42421 tgttaaggac attacagctc ataatactag gcttttttat agaaattctt ttctttttct
    42481 ataggatatg gtattctatg tagaaaatat atgttaataa gtaatgccaa tatttaaaca
    42541 tcattagtaa aaggagttag attgatgaat aaaagaaaag ttagtttaga agatttttat
    42601 aaatggtata gtctaaataa agaagagtta ttaaataagg caactgttgg tgaaaagttt
    42661 aatgataaat taaaagaaga gtttctccag gaatggcctt tggataggat tttaacaatg
    42721 tcaatcgatg aatatgtaat aggaaaggga cagcaaaata agtctttatg ctacgctctt
    42781 gagaagggaa aatacaaaaa tctatttctt ggaatttctg gtggctcagc ttcaaaattt
    42841 ggtatttatt ggaataaaaa aacaaacaaa tataaagatc aagctaataa tgagatttca
    42901 gagttggatc agcgattttc aaaattaaaa tcagatttgt atgaaattat caaagaaggt
    42961 attcgtttta actttgaaaa tcctattttt gatatgaaaa gatcaacaaa tgaatttatt
    43021 ggtcgttctg ctatggtgac aaaattactt tgtatctata ctgagggaga tcctttcttt
    43081 ggtgtaaata ttaatagtca gaaagaattt tggaaccact ttgtttctca gacaaatcaa
    43141 ggtggacctt atctgcaaaa tcataaaata attgaactga tgtccaaaac ttatcctgag
    43201 ttggagccat cgaaattagg aactatgctt tttgagtatt ctaagctttt tatggaaaat
    43261 aaggaagaca atagtacaat ggattcatca aacaattttc gtcatcaatt aactcaatct
    43321 ctattaaagt ctccaaacct tatccttcgt ggtgctcctg gcacaggaaa gacttatctt
    43381 gctaaagaaa ttgccaaaga attaacggat ggcaacgaag atcaaatcgg atttgtacaa
    43441 tttcacccat catatgatta tacggatttt gtagaaggtt taagaccagt atcaaatggg
    43501 gatggagcta ttgagtttag gctacaggac ggtattttta aagatttttg tcagaaagca
    43561 aaagaaaccc aattgattgg aggacaagat aattttgatg aggcttggga ttcttactta
    43621 gaatatataa atgttgctga agaaaaagaa tatataacaa aaacatctta cttatctgtt
    43681 aatagtagac aaaatttgtc agtaaattat gatagtggtg ttccaggatg gtcactacct
    43741 ag
//
LOCUS       DAVBBO010000012        43150 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ST1
            SAMEA2066453-rid20184263.denovo.012, whole genome shotgun sequence.
ACCESSION   DAVBBO010000012 DAVBBO010000000
VERSION     DAVBBO010000012.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2066453
            Sequence Read Archive: ERR351777
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 43150)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 43150)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980402.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980402.1
            Genome Coverage       :: 176x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:17:33
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,141
            CDSs (total)                      :: 2,104
            Genes (coding)                    :: 1,953
            CDSs (with protein)               :: 1,953
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 16S)
            partial rRNAs                     :: 1 (23S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 151
            CDSs (without protein)            :: 151
            Pseudo Genes (ambiguous residues) :: 0 of 151
            Pseudo Genes (frameshifted)       :: 73 of 151
            Pseudo Genes (incomplete)         :: 76 of 151
            Pseudo Genes (internal stop)      :: 40 of 151
            Pseudo Genes (multiple problems)  :: 32 of 151
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..43150
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2066453-rid20184263.denovo.012"
                     /strain="ST1"
                     /db_xref="taxon:1313"
     gene            1..916
                     /locus_tag="VQU30_000630"
                     /pseudo
     CDS             1..916
                     /locus_tag="VQU30_000630"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611512.1"
                     /note="internal stop; incomplete; missing N-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=2
                     /transl_table=11
                     /product="IS3 family transposase"
     gene            complement(961..1602)
                     /gene="plsY"
                     /locus_tag="VQU30_000631"
     CDS             complement(961..1602)
                     /gene="plsY"
                     /locus_tag="VQU30_000631"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000628793.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol-3-phosphate 1-O-acyltransferase PlsY"
                     /protein_id="HET2446789.1"
                     /translation="MITIVLLILAYLLGSIPSGLWIGQVFFQINLREHGSGNTGTTNT
                     FRILGKKAGMATFVIDFFKGTLATLLPIIFHLQGVSPLIFGLLAVIGHTFPIFAGFKG
                     GKAVATSAGVIFGFAPIFCLYLAIIFFGALYLGSMISLSSVTASIAAVIGVLLFPLFG
                     FILSNYDSLFIAIILALASLIIIRHKDNIARIKNKTENLVPWGLNLTHQDPKK"
     gene            1738..3681
                     /gene="parE"
                     /locus_tag="VQU30_000632"
     CDS             1738..3681
                     /gene="parE"
                     /locus_tag="VQU30_000632"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007522163.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase IV subunit B"
                     /protein_id="HET2446790.1"
                     /translation="MSKKEININNYNDDAIQVLEGLDAVRKRPGMYIGSTDGAGLHHL
                     VWEIVDNAVDEALSGFGDRIDVTINKDGSLTVQDHGRGMPTGMHAMGIPTVEVIFTIL
                     HAGGKFGQGGYKTSGGLHGVGSSVVNALSSWLEVEITRDGAVYKQRFENGGKPVTTLK
                     KIGTAPKSKTGTKVTFMPDATIFSTTDFKYNTISERLNESAFLLKNVTLSLTDKRTDE
                     AIEFHYENGVQDFVSYLNEDKEILTPVLYFEGEDNGFQVEVALQYNDGFSDNILSFVN
                     NVRTKDGGTHETGLKSAITKVMNDYARKTGLLKEKDKNLEGSDYREGLAAVLSILVPE
                     EHLQFEGQTKDKLGSPLARPVVDGIVADKLTFFLMENGELASNLIRKAIKARDAREAA
                     RKARDESRNGKKNKKDKGLLSGKLTPAQSKNPAKNELYLVEGDSAGGSAKQGRDRKFQ
                     AILPLRGKVINTAKAKMADILKNEEINTMIYTIGAGVGADFSIEDANYDKIIIMTDAD
                     TDGAHIQTLLLTFFYRYMRPLVEAGHVYIALPPLYKMSKGKGKKEEVAYAWTDGELEE
                     LRKQFGKGATLQRYKGLGEMNADQLWETTMNPETRTLIRVTIEDLARAERRVNVLMGD
                     KVEPRRKWIEDNVKFTLEEATVF"
     gene            4101..6572
                     /gene="parC"
                     /locus_tag="VQU30_000633"
     CDS             4101..6572
                     /gene="parC"
                     /locus_tag="VQU30_000633"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012512618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase IV subunit A"
                     /protein_id="HET2446791.1"
                     /translation="MSNIQNMSLEDIMGERFGRYSKYIIQDRALPDIRDGLKPVQRRI
                     LYSMNKDSNTFDKSYRKSAKSVGNIMGNFHPHGDSSIYDAMVRMSQNWKNREILVEMH
                     GNNGSMDGDPPAAMRYTEARLSEIAGYLLQDIEKNTVPFAWNFDDTEKEPTVLPAAFP
                     NLLVNGSTGISAGYATDIPPHNLAEVIDAAVYMIDHPTAKIDKLMEFLPGPDFPTGAI
                     IQGRDEIKKAYETGKGRVVVRSKTEIEKLKGGKEQIVITEIPYEINKANLVKKIDDVR
                     VNNKVAGIAEVRDESDRDGLRIAIELKKDANTELVLNYLFKYTDLQINYNFNMVAIDN
                     FTPRQVGIVPILSSYIAHRREVILARSRFDKEKAEKRLHIVEGLIRVISILDEVIALI
                     RASENKADAKENLKVSYDFTEEQAEAIVTLQLYRLTNTDVVVLQEEEAELREKIAMLA
                     AIIGDERTMYNLMKKELREVKKKFATPRLSSLEDTAKAIEIDTASLIAEEDTYVSVTK
                     AGYIKRTSPRSFAASTLEEIGKRDDDRLIFVQSAKTTQHLLMFTSLGNVIYRPIHELA
                     DIRWKDIGEHLSQTITNFETNEEILYVEVLDQFDDATTYFAVTRLGQIKRVERKEFTP
                     WRTYRSKSVKYAKLKDDTDQIVAVAPIKLDDVVLVSQNGYALRFNIEEVPVVGAKAAG
                     VKAMNLKEDDVLQSGFICNTSSFYLLTQRGSLKRVSIEEILATSRAKRGLQVLRELKN
                     KPHRVFLAGAVAEQGFVGDFFSTEVDVNDQTLLVQSNKGTIYESRLQDLNLSERTSNG
                     SFISDTISDEEVFDAYLQEVVTEDK"
     gene            6704..7726
                     /locus_tag="VQU30_000634"
     CDS             6704..7726
                     /locus_tag="VQU30_000634"
                     /EC_number="2.6.1.42"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730267.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid aminotransferase"
                     /protein_id="HET2446792.1"
                     /translation="MTVTIDWENLGFSYMKLPYRYLAHFKNGQWDQGELTEDATLHIS
                     ESSPSLHYGQQAFEGLKAYRTKDGSVQLFRPDENAKRLQRTCDRLLMPQVPTDMFVEA
                     CKAVVRANEEYVPPYGTGGTLYLRPLLIGVGDIIGVKPAEEYIFTIFAMPVGNYFKGG
                     LVPTNFLIQDEYDRAAPNGTGAAKVGGNYAASLLPGKMAKSRHFSDVIYLDPSTHTKI
                     EEVGSANFFGITADNEFVTPLSPSILPSITKYSLLYLAEHRLGLTPIEGDVPIDNLDR
                     FVEAGACGTAAVISPIGGIQHGDDFHVFYSETEVGPVTRKLYNELTGIQFGDIEAPEG
                     WIVKVD"
     gene            7782..8486
                     /locus_tag="VQU30_000635"
     CDS             7782..8486
                     /locus_tag="VQU30_000635"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001810388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide ABC transporter substrate-binding
                     protein"
                     /protein_id="HET2446793.1"
                     /translation="MVLSTSAILVACGKTDKEADAPTTFSYVYAVDPASLGYSIATRT
                     SRTDVIGNVIDGLMENDKYGNVAPSQKDYDLNSTGWAPSYQDPASYLNIMDPKSGSDM
                     KHLGITKGKDKDVVAKPGLDKYKKLLEDAVSETTDLEKRYEKYAKAQAWSTDSSLLMP
                     TASSGGFPVVSNVVPFSKPYSQVGIKGEPYIFKGMKLQKDIVTTKEYNEVFKKWQKEK
                     LESNSKYQKELEKYIK"
     gene            8551..9240
                     /locus_tag="VQU30_000636"
     CDS             8551..9240
                     /locus_tag="VQU30_000636"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000454813.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF969 domain-containing protein"
                     /protein_id="HET2446794.1"
                     /translation="MEWIRLIGIAIIVVGFILKFDTIATVVLAGLVTALVSGVSLVEF
                     LEILGKEFSNQRVLTIFMVTLPLVGLSETFGLKQRSIDLIRKIKGLTVGNFYTVYFFI
                     RELAGFFSIRLGGHPQFVRPLVQPMGEAAAESQLGRKLTEVEDETIKARAAANENFGN
                     FFAQNTFVGAGGVLLIGGTLDQLGYESNYAGIASTSIIVAVITLIVVGIYNYLFDKKL
                     ISKKTRGGEQK"
     gene            9237..10160
                     /locus_tag="VQU30_000637"
     CDS             9237..10160
                     /locus_tag="VQU30_000637"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000137271.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF979 domain-containing protein"
                     /protein_id="HET2446795.1"
                     /translation="MTELAKQLLELTYIVIGCQFLHTAYCSYKDKTNPVRLGTSAFWT
                     LLSITFIGGSYMPNMSIGIIVILLSLLTLFKQVRIGTLPSLDEMKANIESNRLKNKIF
                     IPVMLMAILALVLAQMIPEFSKISISLAALFATISVLVITNSHPKSLLSENNRMTQQV
                     STSGIVPQLLGALGAIFTVAGVGDVISHLISGIVPSDSRFIGVLAYVLGMVLFTMIMG
                     NAFAAFTVITAGVGVPFVFALGANPIVAGALAMTAGYCGTLLTPMAANFNALPAALMD
                     MKDQNGVIKAQAGVALVMIVIHIFLMYFLAF"
     gene            10175..10819
                     /gene="pcp"
                     /locus_tag="VQU30_000638"
     CDS             10175..10819
                     /gene="pcp"
                     /locus_tag="VQU30_000638"
                     /EC_number="3.4.19.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398107.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyroglutamyl-peptidase I"
                     /protein_id="HET2446796.1"
                     /translation="MKILVTGFNPFGGEKINPALEAVKLLPSEINGAEVRWVEIPTVF
                     YKSSEVLEAEILRYQPDAVLCIGQAGGRTGLTPERVAINQDDARIPDNEGNQPIDTPI
                     RIDGASAYFSSLPIKAMVQAIKKQGLPAVVSNSAGTFVCNHLMYQALYLVDKKFPNMR
                     AGFMHIPYMMEQVVNKPNTAGMSLCDIVRGIEVAIEAIVDYKDKDLQLVGGETH"
     gene            10987..11217
                     /locus_tag="VQU30_000639"
     CDS             10987..11217
                     /locus_tag="VQU30_000639"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000037109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2969 domain-containing protein"
                     /protein_id="HET2446797.1"
                     /translation="MSKKDKKIEIQVADAKVNVGKDSFEGYTLTIGKKVIGEIAELDG
                     QFAIIKNGNVDSFYKKLEKAVEILIENYNLAK"
     gene            11267..11347
                     /locus_tag="VQU30_000640"
     tRNA            11267..11347
                     /locus_tag="VQU30_000640"
                     /product="tRNA-Tyr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:11301..11303,aa:Tyr,seq:gta)
     gene            11357..11428
                     /locus_tag="VQU30_000641"
     tRNA            11357..11428
                     /locus_tag="VQU30_000641"
                     /product="tRNA-Gln"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:11389..11391,aa:Gln,seq:ttg)
     gene            11590..12792
                     /gene="rpsA"
                     /locus_tag="VQU30_000642"
     CDS             11590..12792
                     /gene="rpsA"
                     /locus_tag="VQU30_000642"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002897515.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S1"
                     /protein_id="HET2446798.1"
                     /translation="MNEFEDLLNSVSQVETGDVVSAEVLTVDATQANVAISGTGVEGV
                     LTLRELTNDRDADINDFVKVGEVLDVLVLRQVVGKDTDTVTYLVSKKRLEARKAWDKL
                     VGREEEVVTVKGTRAVKGGLSVEFEGVRGFIPASMLDTRFVRNAERFVGQEFDTKIKE
                     VNAKENRFILSRREVVEAATAAARAEVFGKLAVGDVVTGKVARITSFGAFIDLGGVDG
                     LVHLTELSHERNVSPKSVVTVGEEIEVKILDLNEEEGRVSLSLKATVPGPWDGVEQKL
                     AKGDVVEGTVKRLTDFGAFVEVLPGIDGLVHVSQISHKRIENPKEALKVGQEVQVKVL
                     EVNADAERVSLSIKALEERPAQEEGQKEEKRAARPRRPRRQEKRDFELPETQTGFSMA
                     DLFGDIEL"
     gene            12878..13375
                     /locus_tag="VQU30_000643"
     CDS             12878..13375
                     /locus_tag="VQU30_000643"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000920162.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GAF domain-containing protein"
                     /protein_id="HET2446799.1"
                     /translation="MLKSEKQSRYQMLNEELSFLLEGETNVLANLSNASALIKSRFPN
                     TVFAGFYLFDGKELVLGPFQGGVSCIRIALGKGVCGEAAHFQETVIVGDVTTYLNYIS
                     CDSLAKSEIVVPMMKNGQLLGVLDLDSSEIEDYDAMDRDYLEQFVAILLEKTTWDFTM
                     FEEKS"
     gene            13375..15030
                     /gene="dnaX"
                     /locus_tag="VQU30_000644"
     CDS             13375..15030
                     /gene="dnaX"
                     /locus_tag="VQU30_000644"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000283769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit gamma/tau"
                     /protein_id="HET2446800.1"
                     /translation="MYQALYRKYRSQNFSQLVGQEVVAKTLKQAVEQEKISHAYLFSG
                     PRGTGKTSVAKIFAKAMNCPNQVGGEPCNNCYICQAVTDGSLEDVIEMDAASNNGVDE
                     IREIRDKSTYAPSLARYKVYIIDEVHMLSTGAFNALLKTLEEPTQNVVFILATTELHK
                     IPATILSRVQRFEFKSIKTQDIKEHIHYILEKENISSEPEAVEIIARRAEGGMRDALS
                     ILDQALSLTQGNELTTAISEEITGTISLSALDDYVAALSQQDVPKALSCLNLLFDNGK
                     SMTRFVTDLLHYLRDLLIVQTGGENTHHSSVFVENLALPQKNLFEMIRLATVSLADIK
                     SSLQPKIYAEMMTVRLAEIKPEPALSGAVENEIATLRQEVARLKQELSNVGAVPKQVA
                     PAPSRPATGKTVYRVDRNKVQSILQEAVENPDLARQNLIRLQNAWGEVIESLGGPDKA
                     LLVGSQPVAANEHHAILAFESNFNAGQTMKRDNLNTMFGNILSQAAGFSPEILAISME
                     EWKEVRAAFSAKAKSSQTEKEVEESLIPEGFEFLADKVKVEED"
     gene            15058..15252
                     /locus_tag="VQU30_000645"
     CDS             15058..15252
                     /locus_tag="VQU30_000645"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001041548.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3272 domain-containing protein"
                     /protein_id="HET2446801.1"
                     /translation="MNKQQFIIMALFTAAETYFFNEAWMTGRYIMAAFWAILLFRNFR
                     VSYVMGKIVDVIDQHFNRKD"
     gene            15402..16172
                     /gene="sufC"
                     /locus_tag="VQU30_000646"
     CDS             15402..16172
                     /gene="sufC"
                     /locus_tag="VQU30_000646"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000114488.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly ATPase SufC"
                     /protein_id="HET2446802.1"
                     /translation="MSVLEIKDLHVEIEGKEILKGVNLTLKTGEIAAIMGPNGTGKST
                     LSAAIMGNPNYEVTKGEVLFDGVNILELEVDERARMGLFLAMQYPSEIPGITNAEFLR
                     AAMNAGKEDDEKISVREFITRLDEKMELLNMKEEMAERYLNEGFSGGEKKRNEILQLL
                     MLEPTFALLDEIDSGLDIDALKVVSKGVNAMRGEGFGAMIITHYQRLLNYITPDVVHV
                     MMEGRVVLSGGPELAARLEREGYAKLAEELGYDYKEEL"
     gene            16200..17462
                     /gene="sufD"
                     /locus_tag="VQU30_000647"
     CDS             16200..17462
                     /gene="sufD"
                     /locus_tag="VQU30_000647"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397189.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly protein SufD"
                     /protein_id="HET2446803.1"
                     /translation="MTRENIKLFSEMHAEPSWLADLRQKAFDKIETLELPVIERVKFH
                     RWNLGDGTITENEPSANVPDFTALDHHLKLVQVGTQTVFEQTPVELAEQGVVFTDFHS
                     ALEEIPELIEEFFMSSVKYDDDKLAAYHTAYFNSGAVLYIPDNVEITEPIEGIFYQDS
                     DSNVPFNKHIMIIAGKNSKINYLERLESRGEGSAKATANITVEVIARSGAQVKFAAID
                     RLGENVTAYISRRGKLGNDASIDWAIGVMNEGNVVADFDSDLIGNGSYADLKVVALSS
                     GRQVQGIDTRVTNYGCNSIGNILQHGVILEKATLTFNGIGHIIKGAKGADAQQESRVL
                     MLSDQARSDANPILLIDENDVTAGHAASIGQVDPEDMYYLMSRGLDKATAERLVVRGF
                     LGSVIVEIPVKEVRDEMIATIEEKLSKR"
     gene            17473..18699
                     /locus_tag="VQU30_000648"
     CDS             17473..18699
                     /locus_tag="VQU30_000648"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000887707.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase"
                     /protein_id="HET2446804.1"
                     /translation="MLDVEAIRKDFPILDQIVNDEPLVYLDNAATTQKPLVVLKAINS
                     YYEQDNANVHRGVHTLAERATASYEAARETIRKFINAGSTKEVLFTRGTTTSLNWVAR
                     FAEEILTEGDQVLISVMEHHSNIIPWQEACRKTGAELVYVYLKDGALDMEDLRAKLTD
                     KVKFVSLAHASNVLGVVNPIKEITQLAHQVGAIMVVDGAQSTPHMKIDVQDLDLDFFA
                     FSGHKMAGPTGIGVLYGKEKYLEQMSPVEFGGEMIDFVYEQSASWKELPWKFEAGTPN
                     MAGAIGLATAVDYLEKIGMDAVEAHEQELIAYVYPKLQAIEGLTIYGSQDLAQRSGVI
                     AFNLGDLHPHDLATALDYEGVAVRAGHHCAQPLLQYLEVPASARASFYIYNTKADCDK
                     LVDALQKTKEFFNGTF"
     gene            18686..19126
                     /locus_tag="VQU30_000649"
     CDS             18686..19126
                     /locus_tag="VQU30_000649"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397187.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SUF system NifU family Fe-S cluster assembly
                     protein"
                     /protein_id="HET2446805.1"
                     /translation="MALSKLDSLYMAVVADHSKNPHHQGKLEDAEQISLNNPTCGDVI
                     NLSVKFDAEDRLEDIAFLNSGCTISTASASMMTDAVLGKTKQEILELATIFSEMVQGQ
                     KDERQDQLGDAAFLSGVAKFPQRIKCATLAWNALKKTIENQEKQ"
     gene            19176..20588
                     /gene="sufB"
                     /locus_tag="VQU30_000650"
     CDS             19176..20588
                     /gene="sufB"
                     /locus_tag="VQU30_000650"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly protein SufB"
                     /protein_id="HET2446806.1"
                     /translation="MAEERVEPKPIDLGEYKFGFHDDVEPVLSTGKGLNEGVIRELSA
                     AKGEPEWMLEFRLKSYETFKKMPMQTWGADLSEIDFDDLIYYQKPSDKPARSWDDVPE
                     KIKETFERIGIPEAERAYLAGASAQYESEVVYHNMKEEFQKLGIIFTDTDSALKEYPD
                     LFKQYFAKLVPPTDNKLAALNSAVWSGGTFIYVPKGVKVDIPLQTYFRINNENIGQFE
                     RTLIIVDEGASVHYVEGCTAPTYSSNSLHAAIVEIFALDGAYMRYTTIQNWSDNVYNL
                     VTKRAKAQKDATVEWIDGNLGAKTTMKYPSVYLDGEGARGTMLSIAFANAGQHQDTGA
                     KMIHNAPHTSSSIVSKSIAKGGGKVDYRGQVTFNKNSKKSVSHIECDTIIMDDLSASD
                     TIPFNEIHNSQVALEHEAKVSKISEEQLYYLMSRGLSESEATEMIVMGFVEPFTKELP
                     MEYAVELNRLISYEMEGSVG"
     gene            complement(20819..22060)
                     /locus_tag="VQU30_000651"
     CDS             complement(20819..22060)
                     /locus_tag="VQU30_000651"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-D-alanine carboxypeptidase"
                     /protein_id="HET2446807.1"
                     /translation="MKKIFLTLLTVSLLGGASTAVAQDFTIAAKHAIAVEANTGKILY
                     EKDATQPVEIASITKLITAYLVYEALENGSITLSTPVDISDYPYQLTTNSEASNIPME
                     ARNYTVEELLEATLVSSANSAAIALAEKIAGSEKDFIDMMRAKLLEWGIQDATVVNTT
                     GLNNETLGDNIYPGSKKDEENKLSAYDVAIVARNLIKKYPQVLEITKKPSSTFAGMTI
                     TSTNYMLEGMPAYRGGFDGLKTGTTDKAGESFVGTTVEKGMRVITVVLNADHQDNNPY
                     ARFTATSSLMDYISSTFTLRKIVQQGDAYQDSKAPVQDGKEDTVTAVAPEDIYLIERV
                     GNQSSQSVQFTPDSKAIPAPLEAGTVVGHLTYEDKDLIGQGYITTERPSFEMVADKKI
                     EKAFFLKVWWNQFVRFVNEKL"
     gene            22163..23272
                     /locus_tag="VQU30_000652"
     CDS             22163..23272
                     /locus_tag="VQU30_000652"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000489839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HET2446808.1"
                     /translation="MFRRNKLFFWTTEILLLTIIFYLWRQMGSLINPFVSVLNTIMIP
                     FLLGGFLYYLTNPIVTFLNKVCKLNRLLGILITLCTLVWGMVIGVVYLLPILINQLSS
                     LIISSQTIYSRVQDLIIDLSNYPALQNLDVEATIQQLNLSYVDILQNILNSVSNSVGS
                     VLSALISTVLILIMTPVFLVYFLLDGHKFLPMLERTILKRDRLHIAGLLKNLNATIAR
                     YISGVSIDAIIIGCLAYIGYSIIGLKYALVFAIFSGVANLIPYVGPSIGLIPMIIANI
                     FTDPHRLLIAVIYMLVVQQVDGNILYPRIVGSVMKVHPITILVLLLLSSNIYGVVGMI
                     VAVPTYSILKEISKFLSRLYENHKIMKERERELAK"
     gene            23806..24153
                     /gene="ssrA"
                     /locus_tag="VQU30_000653"
     tmRNA           23806..24153
                     /gene="ssrA"
                     /locus_tag="VQU30_000653"
                     /product="transfer-messenger RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00023"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00023"
     gene            complement(24336..24423)
                     /locus_tag="VQU30_000654"
     tRNA            complement(24336..24423)
                     /locus_tag="VQU30_000654"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(24387..24389),aa:Ser,seq:gga)
     gene            24585..25325
                     /locus_tag="VQU30_000655"
     CDS             24585..25325
                     /locus_tag="VQU30_000655"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000920650.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HET2446809.1"
                     /translation="MLKTERKQLILEELNQHHVVSLEKLVSLLETSESTVRRDLDELE
                     AENKLRRVHGGAELPHSLQEEETIQEKSVKNLQEKKLLAQKAASLIKEKDVIFIDAGT
                     TTAFLIHELVNKNITVVTNSIHHAAQLVEKQIPTVMVGGNVKTATDASIGGVALNQIN
                     QLHFDRAFIGMNGVDDGYYTTPDMEEGAVKRAILENAKQTYVLVDSSKIGQTCFAKVA
                     PLKRAIVITSQGHELLQVIKEKTEVIEV"
     gene            25322..26233
                     /gene="pfkB"
                     /locus_tag="VQU30_000656"
     CDS             25322..26233
                     /gene="pfkB"
                     /locus_tag="VQU30_000656"
                     /EC_number="2.7.1.56"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015605104.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-phosphofructokinase"
                     /protein_id="HET2446810.1"
                     /translation="MIYTVTLNPSIDYIVRLDQVKVGSVNRMDSDDKFAGGKGINVSR
                     VLKRLNIPNTATGFIGGFTGKFITDTLAEEEIETRFVQVAEDTRINVKIKADQETEIN
                     GTGPTVESVQLEELKAILSSLTAEDTVVFAGSSAKNLGNVIYKDLISLTRQTGAQVVC
                     DFEGQTLIDSLDYQPLLVKPNNHELGAIFGVKLESLDEIEKYARELLAKGAQNVIISM
                     AGDGALLVTSEGAYFAKPIKGTVKNSVGAGDSMVAGFTGEFVKSKDVVEAFKWGVACG
                     TATTFSDDLATAEFIKETYGKVEVEKR"
     gene            26230..28182
                     /locus_tag="VQU30_000657"
     CDS             26230..28182
                     /locus_tag="VQU30_000657"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000701424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HET2446811.1"
                     /translation="MKIQDLLRKDVMLLDLQATEKTAVIDEMIKNLTDHGYVTDFETF
                     KEGILAREALTSTGLGDGIAMPHSKNAAVKEATVLFAKSNKGVDYESLDGQATDLFFM
                     IAAPEGANDTHLAALAELSQYLMKDGFADKLRQATSADQVIELFDQASEKTEELVQAP
                     ANDSGDFIVAVTACTTGIAHTYMAQEALQKVAAEMGVGIKVETNGASGVGNQLTAEDI
                     RKAKAIIIAADKAVEMDRFDGKPLINRPVADGIRKTEELINLALSGDTEVYRAANGAK
                     AATASNEKQSLGGALYKHLMSGVSQMLPFVIGGGIMIALAFLIDGALGVPNENLGNLG
                     SYHELASMFMKIGGAAFGLMLPVFAGYVAYSIAEKPGLVAGFVAGAIAKEGFAFGKIP
                     YAAGGEATSTLAGVSSGFLGALVGGFIAGALVLAIKKYVKVPRSLEGAKSILLLPLLG
                     TILTGFVMLAVNIPMAAINTAMNDFLGGLGGGSAVLLGIVLGGMMAVDMGGPVNKAAY
                     VFGTGTLAATVSSGGSVAMAAVMAGGMVPPLAIFVATLLFKDKFTKEERNSGLTNIIM
                     GLSFITEGAIPFGAADPARAIPSFILGSAVAGGLVGLTGIKLMAPHGGIFVIALTSNA
                     LLYLVSVLVGAIVSGVVYGYLRKPQA"
     gene            28346..30571
                     /locus_tag="VQU30_000658"
     CDS             28346..30571
                     /locus_tag="VQU30_000658"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000908822.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA translocase FtsK"
                     /protein_id="HET2446812.1"
                     /translation="MLISLGIAILLIFAAFKLGAAGITLYNLIRLLVGSLAYLAIFGL
                     LIYLFFFKWIRKQEGLLSGFFTIFAGLLLIFEAYLVWKYGLDKSVLKGTMAQVVTDLT
                     GFRTTSFAGGGLIGVALYIPTAFLFSNIGTYFIGSILILVGSLLVSPWSVYDIAEFFS
                     RGFAKWWEGHERRKEERFVKQEEKARQKAEKEARLEQEETEKALLDLPPVDMETGEIL
                     TEEAVQNLPPIPEEKWVEPEIILPQAELKFPEQEDDSDDEDVQVDFSAKEALEYKLPS
                     LQLFAPDKPKDQSKEKKIVRENIKILEATFASFGIKVTVERAEIGPSVTKYEVKPAVG
                     VRVNRISNLSDDLALALAAKDVRIEAPIPGKSLIGIEVPNSDIATVSFRELWEQSQTK
                     AENFLEIPLGKAVNGTARAFDLSKMPHLLVAGSTGSGKSVAVNGIIASILMKARPDQV
                     KFMMVDPKMVELSVYNDIPHLLIPVVTNPRKASKALQKVVDEMENRYELFAKVGVRNI
                     AGFNAKVEEFNSQSEYKQIPLPFIVVIVDELADLMMVASKEVEDAIIRLGQKARAAGI
                     HMILATQRPSVDVISGLIKANVPSRVAFAVSSGTDSRTILDENGAEKLLGRGDMLFKP
                     IDENHPVRLQGSFISDDDVERIVNFIKTQADADYDESFDPGEVSENEGEFSDGDAGGD
                     PLFEEAKSLVIETQKASASMIQRRLSVGFNRATRLMEELEIAGVIGPAEGTKPRKVLQ
                     Q"
     gene            complement(30616..31044)
                     /locus_tag="VQU30_000659"
     CDS             complement(30616..31044)
                     /locus_tag="VQU30_000659"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000073927.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2446813.1"
                     /translation="MSNYRRTSKPKTEHIKKGFTVFQKTVATIASILGLITASITIMN
                     ALDNNKNIKKEPTTSQTTTIVKEIQKESPKENTSPTKETNTSQEKTQQEETPKSSVKE
                     EKKEDQKTATQDSSTPASSKPATENEKQSNAPTSENKSNQ"
     gene            31182..32324
                     /locus_tag="VQU30_000660"
     CDS             31182..32324
                     /locus_tag="VQU30_000660"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000638948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase"
                     /protein_id="HET2446814.1"
                     /translation="MIYFDNSATTKPYPEALETYMQVASKILGNPSSLHRLGDQATRI
                     LDASRQQIADLIGKKSDEIFFTSGGTEGDNWLIKGVAFEKAQFGKHIIVSAIEHPAVK
                     ESALWLKSQGFEVDFAPVDKKGLVDVEALAGLIRHDTILVSIMAVNNEIGSIQPIEAI
                     SEFLADKPTISFHVDAVQALAKIPTEKYLTERVDCATFSSHKFHGVRGVGFVYIKSGK
                     KITPLLTGGGQERDYRSTTENVAGIAATAKALRLSMEKLDIFRSKTGQMKAVIRQALL
                     NYPDIFVFSDEENFAPHILTFGIKGVRGEVIVHAFEDYDIFISTTSACSSKAGKPAGT
                     LIAMGVDKDKAKSAVRLSLDLENDMSQVEQFLTKLKLIYNQTRKVR"
     gene            32333..33547
                     /gene="thiI"
                     /locus_tag="VQU30_000661"
     CDS             32333..33547
                     /gene="thiI"
                     /locus_tag="VQU30_000661"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001200101.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA 4-thiouridine(8) synthase ThiI"
                     /protein_id="HET2446815.1"
                     /translation="MQYSEIMIRYGELSTKGKNRMRFINKLRNNISDVLSIYTQVKVT
                     ADRDRAHAYLNGADYTAVAESLKQVFGIQNFSPVYKVEKSVEVLKSSVQEIMRDIYKE
                     GMTFKISSKRSDHNFELDSRELNQTLGGAVFEAIPNVQVQMKSPDINLQVEIREEAAY
                     LSYETIRGAGGLPVGTSGKGMLMLSGGIDSPVAGYLALKRGVDIEAVHFASPPYTSPG
                     ALKKAQDLTRKLTKFGGNIQFIEVPFTEIQEEIKAKAPEAYLMTLTRRFMMRITDRIR
                     EVRNGLVIINGESLGQVASQTLESMKAINAVTNTPIIRPVVTMDKLEIIDIAQEIDTF
                     DISIQPFEDCCTIFAPDRPKTNPKIKNAEQYEARMDVEGLVERAVAGIMITEITPQAE
                     KDEVDDLIDNLL"
     gene            33682..34506
                     /locus_tag="VQU30_000662"
     CDS             33682..34506
                     /locus_tag="VQU30_000662"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001076725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HET2446816.1"
                     /translation="MNQSYFYLKMKEHKLKVPYTGKERRVRILLPKDYEKDTDRSYPV
                     VYFHDGQNVFNSKESFIGHSWKIIPAIKRNPDISRMIVVAIDNDGMGRMNEYAAWKFQ
                     ESPIPGQQFGGKGVEYAEFVMEVVKPFIDETYRTKADCQHTAMIGSSLGGNITQFIGL
                     EYQDQIGCLGVFSSANWLHQEAFNRYFECQKLSPDQRIFIYVGTEEADDTDKTLMDGN
                     IKQAYIDSSLCYYHDLIAGGVHLDNLVLKVQSGAIHSEIPWSENLPDCLRFFAEKW"
     gene            34528..35267
                     /locus_tag="VQU30_000663"
                     /pseudo
     CDS             34528..35267
                     /locus_tag="VQU30_000663"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000546805.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="esterase family protein"
     gene            35280..36446
                     /locus_tag="VQU30_000664"
     CDS             35280..36446
                     /locus_tag="VQU30_000664"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001108652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-grasp domain-containing protein"
                     /protein_id="HET2446817.1"
                     /translation="MNYLVISPYYPQNFQQFTIELANKGITVLGIGQESYEQLDEPLR
                     NSLTEYFRVDNLENIDEVKRAVAFLFYKHGPIGRIESHNEYWLELDATLREQFNVFGA
                     KPEDLKKTKYKSEMKKLFKKAGVPVVPGAVIKTEADVDQAVKEIGLPMIAKPDNGVGA
                     AATFKLETEDDINHFKQEWDHSTLYFFEKFVTSSEICTFDGLVDKDGKIVFSTTFDYA
                     YTPLDLMIYKMDNSYYVLKDMDPKLRKYGEAIVKEFGMKERFFHIEFFREGDDYITIE
                     YNNRPAGGFTIDVYNFAHSLDLYRGYAAIVAGEEFPASDFETQYCLATSRRANAHYVY
                     SEEDLLAKYSQQFKVKKVMPAAFAELQGDYLYMLTTPSRQEMEQMIADFGQRQE"
     gene            36954..38447
                     /locus_tag="VQU30_000665"
     CDS             36954..38447
                     /locus_tag="VQU30_000665"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000627753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SAM-dependent DNA methyltransferase"
                     /protein_id="HET2446818.1"
                     /translation="MITGELKNKIDQLWEILWTEGNANPLTNIEQLTYLLFMKDLDSV
                     ELGRESDAEFLGIPYEGVFPKDKPEYRWSTFKNIGDAQEVYRLMTQEIFPFIKNLKGD
                     TDDTAFSRYMREAIFQINKPATLQKAISILDVFPTRGLDVDFDNDKQSITDIGDIYEY
                     LLSKLSTAGKNGQFRTPRHIIDMMVELMQPTIKDIISDPAMGSAGFLVSASRYLKRKK
                     DEWETNTDNINHFHNQMFHGNDTDTTMLRLGAMNMMLHGVENPQISYLDSLSQDNEEA
                     DKYTLVLANPPFKGSLDYNSTSNDLLATVKTKKTELLFLSLFLRTLKPGGRAAVIVPD
                     GVLFGSSKAHKGIRQEIVENHKLDAVISMPSGVFKPYAGVSTAILIFTKTGNGGTDKV
                     WFYDMKADGLSLDDKRQPISDNDIPDIIERFHHLEKEAERQRTDQSFFVPVAEIKEND
                     YDLSINKYKEIEYEKVEYEPTEVILKKINDLEKEIQAGLAELEKLLK"
     gene            38460..39506
                     /locus_tag="VQU30_000666"
     CDS             38460..39506
                     /locus_tag="VQU30_000666"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000756103.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HET2446819.1"
                     /translation="MKKVKLGEVLSLKKGKKATVLAEQTTLSQRYIQIDDLRNNNNLK
                     FTESLNMTEALPDDILIAWDGANAGTVGYGLSGAVGSTITVLKKNERYKEKIISDYLG
                     VFLESKSQYLREHSTGATIPHLNKNILLDLQLELLGIEEQENIICILNTIKRLITKRK
                     LQLDELNLLVKSRFNEMFGDVILNEKEWKVSKWNEILTIRNGKNQKQVEDADGKFPIY
                     GSGGIMGYAKDWIVKKNSVIIGRKGNINKPILVRENFWNVDTAFGLEPVLEKINSEYL
                     FYFCQLYNFEKLNKAVTIPSLTKSDLLNISIPLPPLALQNEFADFVALVDKSQFACEI
                     AIKVWRNSLKFSII"
     gene            39536..42232
                     /locus_tag="VQU30_000667"
                     /pseudo
     CDS             39536..42232
                     /locus_tag="VQU30_000667"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000526318.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase family protein"
     gene            complement(42266..>43150)
                     /locus_tag="VQU30_000668"
     CDS             complement(42266..>43150)
                     /locus_tag="VQU30_000668"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001856869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
                     /protein_id="HET2446820.1"
                     /translation="HQLAISTSTVIRKLNDFHFEHDFSRLPKIMSWDEYAFTKGKMSF
                     IAQDFDNLNIITVLEGRTQAVIRNHFLRYDRAVRCQVKIITMDMFSPYYDLAKQLFPC
                     AKIVLDRFHIIQHLSRAMSRFRVQIMNQFERKSHEYKAIKRYWKLIQQDSRKLSDKRF
                     YRPTFRMHLTNKEILDKILSYSEDLKHHYQIYQLLLFHFQNKDPEKFFGLIEDNLKQV
                     HPLFQTVFKTFLKNKEKIVNALQLHYSNAKLEATNNLIKLIKRNAFGFRNFENFKKRI
                     FIALNIKKERTKFVLSQA"
BASE COUNT        13142 a         7741 c         9533 g        12734 t
ORIGIN      
        1 atgccatcct aaaaaagtta agagaactcc gattgaagga ggaaaaagag aaagaagaaa
       61 gacagaaatt attcaagaat taatgactga gttttcgtta gatcttcttc taaaagccat
      121 taaactagct cgttcgacct actactatca cttgaaacag ctagacaaaa cagataagga
      181 ccaagagctt aaagctgaaa ttcaatccat ttttatcgaa cacaagggaa attatggtta
      241 tcgtcgaatt tatttagaac taagaaatcg tgcttatctg gtaaatcata aaagagttca
      301 aggcttgatg aaagtactca atttacaagc taaaatgcga cagaaacgaa aatattcttc
      361 tcataaagga gacgttggca agaaggcaga gaatctcatt caaggccaat ttgaaggctc
      421 taaaacaatg gaaaagtgct acacagatgt gacagaattt gccattccag caagtactca
      481 aaagctttac ttatcaccag ttttagatgg ctttaacagc gaaattatcg cctataatct
      541 ttcaacttcg cccaacttag aacaagtata aacaatgttg gaacaggcat tcaaagagaa
      601 gcactacgag aatacgattc tccatagtga ccaaggctgg caatatcaac acgattctta
      661 tcatcagttc ctagagagta agggaattca agcatccatg tcacgtaagg gaaacagccc
      721 agacaatggt atgatggagt ccttctttgg gattctgaaa tcggaaatgt tttacggtta
      781 tgagaagtcg tttcagtcgc ttaagcaatt ggaacaagcc attatagact atattgatta
      841 ctacaacaat aaacgaatta agataaaact aaaaggactt agccctgtgc aatacagaac
      901 taaatccttc ggataaatta attgtctaac ttttggggtg cagttcacag aactggcatt
      961 ttatttttta ggatcttgat gggttaggtt caatccccaa gggaccaaat tttcagtttt
     1021 atttttgata cgagctatat tgtccttatg acgaatgata atcaaactag caagtgctaa
     1081 gataatagcg atgaagagag agtcatagtt actcaggata aaaccaaaaa gtggaaagag
     1141 cagaaccccg ataacagccg cgatcgatgc tgtgacacta gacagtgaaa tcatactgcc
     1201 aagatagaga gctccaaaga agataatcgc aaggtagaga cagaagatag gcgcaaatcc
     1261 gaaaattact ccagcactgg ttgcgacagc cttaccacct ttaaatcctg caaagatagg
     1321 gaaggtatgg ccgataacag ccaaaagtcc aaagatgaga ggagaaacgc cttgtagatg
     1381 aaaaataatc ggaagcagcg ttgctagggt tcctttgaaa aagtcaatca caaaggttgc
     1441 cataccagct ttcttaccta aaatgcggaa ggtattggtc gttccagtgt taccagaacc
     1501 atgctcgcgt agattgattt gaaagaatac ttgtccaatc cagagaccag atggaatcga
     1561 acccagcaga taggctagga ttaataaaac tattgtaatc atactcctat tatatcatga
     1621 attgggaaag aaaagcagag aatctctgct aaaattgtca catcggagaa agaaaaattt
     1681 tgcaaaatcc ttggaaaacc tgtagaatag taaagatgaa cgaataggag gttccttgtg
     1741 tcaaaaaagg aaatcaatat taacaattat aatgatgatg ctattcaggt gctagaaggg
     1801 ttggatgcgg tccgaaaacg tccagggatg tatattggat cgaccgatgg cgctggtctt
     1861 catcacctag tttgggaaat cgttgataat gcagtcgatg aagccttgtc tgggtttggt
     1921 gatcgtatcg atgtaaccat caataaagac ggtagtctaa cggttcaaga ccatggacgt
     1981 gggatgccga caggtatgca cgctatggga attccaactg ttgaggttat ctttaccatt
     2041 cttcatgccg gagggaaatt cggtcaaggt ggctataaga catcaggtgg acttcacgga
     2101 gtgggttctt ccgttgttaa cgccctttct agctggttag aagttgaaat tacccgtgat
     2161 ggcgcagttt acaagcaacg tttcgaaaat ggtggaaaac ctgtcacgac tttgaagaaa
     2221 atcggtacag cacccaagtc taaaacaggc accaaagtta cttttatgcc tgacgcgact
     2281 atattttcta cgacagattt caagtacaat accatttcag agcgccttaa tgaatcagcc
     2341 tttctcttga aaaatgtgac cttgtcttta acggacaagc gaacagatga agcgattgag
     2401 ttccactatg agaatggagt acaagatttt gtttcttatc tcaacgaaga taaggaaatc
     2461 ttgacgccag ttctttactt tgaaggggaa gacaatggtt ttcaagtgga agtagccctc
     2521 cagtacaatg acggattctc agataacatt ctatcctttg tcaataacgt tcgcaccaag
     2581 gacggtggaa cgcacgagac aggactcaag tctgccatta ccaaggtcat gaatgactat
     2641 gcacgtaaaa caggtcttct caaggaaaaa gataaaaacc ttgaaggttc agactatcgt
     2701 gagggactag cggccgttct ttctatctta gttcctgaag aacacttgca gtttgaagga
     2761 cagaccaagg ataaactagg aagcccccta gctcgcccag ttgtggatgg aatagtggct
     2821 gataagttga cctttttcct tatggaaaat ggggaattag cttctaacct catccgcaag
     2881 gctatcaagg cccgtgatgc tcgtgaagca gcacgtaagg cgcgtgatga gagccgaaat
     2941 gggaagaaaa acaagaaaga taagggcttg ttgtctggga aattgacccc agcccaatct
     3001 aagaatcctg ctaagaatga actctatcta gttgaggggg actctgccgg tggttctgcc
     3061 aaacaaggtc gtgaccgcaa gttccaggct attctacctc ttcgtggtaa ggttatcaat
     3121 acagccaagg ccaagatggc ggatatcctc aaaaatgaag agatcaatac catgatttat
     3181 accattggtg cgggtgttgg agcagacttc tctattgaag atgccaacta tgataagatc
     3241 attatcatga ccgatgcgga taccgacggt gcccatatcc agaccttgct cttgacattt
     3301 ttctaccgtt acatgcgtcc gctagtcgag gcaggtcatg tctatattgc cctcccacct
     3361 ctttacaaga tgtccaaagg taaaggaaag aaagaagaag tggcctacgc ttggacggac
     3421 ggagaactag aagaactccg taaacagttc ggtaaaggcg ctaccctcca acgatacaaa
     3481 ggacttggtg agatgaatgc ggaccagctc tgggaaacaa ccatgaaccc agaaacacgt
     3541 accctcatcc gtgtcacaat tgaagattta gcgcgcgccg aacgccgcgt caatgttctc
     3601 atgggagata aggtagaacc acgccgtaaa tggattgaag ataatgtcaa gtttacgcta
     3661 gaagaagcga cagtgtttta atgaaagaaa ataatatgtt agtaaactgg aaattagagt
     3721 cggatgtgaa tgactatgtg aaaaagcagt ttgaaaatct tggtttgaaa aaattgcagg
     3781 attattaatg aagaatctgc tatgagtgct tatctcaaag aggcgcttaa gggagcggct
     3841 aagacacaaa ctaagactaa ttttggaaaa ccagattttc atattgaaaa atacaaacag
     3901 gatagtttgg ttacttatcg taactgaaca cgggaggaat tcccgtaaaa tatcttttac
     3961 tgcataaaaa cctactctac attctttgaa aggagttgaa cacgccctag atactgtgtg
     4021 aaaaagataa attctcttgt gagtttgctt acttcaagaa ttttctattt tcacttggta
     4081 ttttatgggc tttgtatctt atgtctaaca ttcaaaacat gtccctggag gacatcatgg
     4141 gagagcgctt tggtcgctac tccaagtaca ttattcaaga ccgggctttg ccagatattc
     4201 gtgatgggtt gaagccggtt cagcgccgta ttctttattc tatgaataag gatagcaata
     4261 cttttgacaa gagctaccgt aagtcggcca agtcagtcgg gaacatcatg gggaatttcc
     4321 acccacacgg ggattcttct atctatgatg ccatggttcg tatgtcacag aactggaaaa
     4381 atcgtgagat tctagttgaa atgcacggta ataacggttc tatggacgga gatcctcctg
     4441 cggctatgcg ttatactgag gcacgtttgt ctgaaattgc aggttacctt cttcaggata
     4501 tcgagaaaaa tacagttcct tttgcatgga actttgacga tacggagaaa gaaccaacgg
     4561 tcttgccagc agcctttcca aacctcttgg tcaatggttc gactgggatt tcggctggtt
     4621 atgccacaga cattcctccc cataatttag ctgaggtcat agatgctgca gtttacatga
     4681 ttgaccaccc aactgcaaag attgataaac tcatggaatt cttgcctgga ccagacttcc
     4741 ctacaggggc tattattcag ggtcgtgatg aaatcaagaa agcttatgag actgggaaag
     4801 ggcgcgtggt tgttcgttcc aagactgaaa ttgaaaagct aaaaggtggt aaggaacaaa
     4861 tcgttattac tgagattcct tatgaaatca ataaggccaa tctagtcaag aaaatcgatg
     4921 atgttcgtgt taataacaag gtagctggga ttgctgaggt tcgtgatgag tctgaccgtg
     4981 atggtcttcg tatcgctatc gaacttaaga aagacgctaa tactgagctt gttctcaact
     5041 acttatttaa gtacaccgac ctacaaatca actacaactt taatatggtg gcgattgaca
     5101 atttcacacc tcgtcaggtt gggattgttc caatcctgtc tagctacatc gctcaccgtc
     5161 gagaagtgat tttggcgcgt tcacgctttg acaaagaaaa ggctgagaaa cgtctccata
     5221 tcgtcgaagg tttgattcgt gtgatttcga ttttggatga agtcattgct cttatccgtg
     5281 cttctgagaa taaggcggac gccaaggaaa acctcaaagt tagctatgat tttacggaag
     5341 aacaggctga ggctatcgta actttgcaac tgtaccgttt gaccaatacc gatgtggttg
     5401 tcttgcagga agaagaagca gagcttcgtg agaagattgc tatgctggcg gctattatcg
     5461 gtgatgaaag gactatgtac aatctcatga agaaagaact tcgtgaggtc aagaagaaat
     5521 ttgcaactcc tcgtttgagt tctttagaag acactgcgaa agcaattgag attgatacag
     5581 ctagtcttat cgctgaggaa gatacctacg tcagcgtgac caaggcaggt tacatcaagc
     5641 gtaccagtcc acgttccttt gcggcttcca ccttggaaga aattggcaag cgtgatgatg
     5701 accgtttgat ttttgttcaa tctgccaaga caacccagca cctcttgatg ttcacaagtc
     5761 ttggaaatgt catctacaga ccaatccatg agttggcaga tattcgttgg aaggacatcg
     5821 gagagcatct gagccaaacc atcacaaact ttgaaacgaa tgaagaaatc ctttatgtgg
     5881 aagtactgga tcagtttgac gatgcgacaa cctactttgc agtgactcgc cttggtcaaa
     5941 tcaaacgggt agagcgaaaa gaattcactc catggcggac ctatagatct aagtctgtca
     6001 agtatgctaa gctcaaagac gatacagatc agattgtagc agtggctccg attaaactag
     6061 atgatgttgt cttggttagt caaaatggtt atgccctgcg tttcaatatc gaagaggttc
     6121 cggttgtcgg tgctaaggca gcaggtgtca aggctatgaa tttgaaagaa gatgatgtcc
     6181 tccaatctgg ctttatctgt aatacttcgt ccttctacct cttgacccag cgtggaagct
     6241 tgaaacgtgt ttctattgag gaaattctag caaccagccg tgccaaacga ggattacaag
     6301 tcttgcgtga gttgaaaaac aaaccgcatc gtgtcttctt ggcaggagca gttgcagagc
     6361 aaggatttgt tggcgatttc ttcagtacgg aagtggatgt gaacgaccaa actctgcttg
     6421 tccaatccaa taaaggaaca atctatgaaa gccgattgca agacttgaac ttgtcagaac
     6481 gcactagcaa tggaagcttc atttctgaca cgatttcaga tgaagaagtt tttgacgctt
     6541 atcttcagga agtagttact gaagataaat aagtgaaatg aagaatcagt tctaagagct
     6601 ggtttttatt ggagaaattt tctgaaaatt acaaaatata cttgctattt tagaaaaata
     6661 gtgtagaata taagaaatag gtttttagaa taaggagtgg aatatgacag taacgattga
     6721 ttgggaaaac ctcggttttt cctatatgaa attaccttat cgctatcttg ctcatttcaa
     6781 aaatggacaa tgggatcaag gagagcttac agaggatgca actttgcata tttcagagtc
     6841 ttctccaagt cttcactatg gacaacaagc atttgaaggt ttgaaagctt atcgtactaa
     6901 ggatggcagt gttcaactgt tccgtcctga tgaaaatgct aaacgtctgc aacgtacatg
     6961 tgaccgtctc ttgatgccac aagttccgac agacatgttt gtagaagctt gtaaagcagt
     7021 tgtccgtgcg aatgaagaat acgtaccacc atacggaaca ggtggaacct tatatcttcg
     7081 ccctcttttg attggtgtcg gagatattat cggggtaaaa ccggcagaag agtacatttt
     7141 caccatcttt gctatgccag ttggaaatta ctttaaaggt ggtttggtcc caaccaactt
     7201 cttgattcag gatgagtacg accgtgcagc accaaatggt acaggtgcgg ctaaggttgg
     7261 tggaaactat gctgcaagtc tcttaccagg aaaaatggcc aagtcacgtc atttctcaga
     7321 tgttatctat ctggacccat caactcatac aaagattgaa gaagtcggat cagctaactt
     7381 ctttggaatt acagctgata atgaatttgt aacaccattg agtccatcta tcttgccatc
     7441 tattaccaag tattccttgc tttatttggc agaacatcgc ttgggattaa ctcctattga
     7501 gggtgatgtt ccaattgata atcttgaccg ttttgtagag gcaggtgcct gtggtacagc
     7561 agcggttatt tctccaattg gaggtattca acatggtgat gatttccatg tattctatag
     7621 tgaaacagaa gtaggtcctg tgacgcgtaa attatataat gaattgacgg gtattcagtt
     7681 tggcgatatt gaagcgccag aaggttggat tgtaaaagta gattaaaata aaccaaagga
     7741 gattttttat gaaatagaaa aagtggctct taacagcagg agtggtcctg agcacgtcag
     7801 ctattttagt ggcttgtgga aaaactgata aagaagcaga tgcaccgaca acattttctt
     7861 atgtctatgc agtagatcca gcatcattgg gctacagtat agcgactcga acatcgagga
     7921 cagacgttat tggaaatgtt attgatggtt tgatggaaaa tgataaatac ggcaatgttg
     7981 ctccttctca aaaagactat gatttgaaca gtacaggatg ggctccaagc tatcaagatc
     8041 cagcgtctta cttgaatatt atggatccaa aatctggttc tgacatgaaa caccttggca
     8101 ttacgaaagg aaaagataag gatgttgtag ctaaacctgg tttggataaa tataagaaat
     8161 tgttagaaga tgctgtttct gagaccactg acctagagaa gagatatgaa aaatatgcca
     8221 aagctcaagc ttggtcgaca gatagttcat tattgatgcc aacagcttca tctggtggtt
     8281 ttccagttgt aagtaacgta gtaccattct caaaaccata ctcacaagtt ggtattaagg
     8341 gggaaccata tatctttaaa ggaatgaaat tgcaaaaaga tattgttaca acaaaagaat
     8401 ataacgaggt ttttaaaaaa tggcaaaaag aaaaattgga atccaatagc aaataccaaa
     8461 aagaactaga aaaatacatt aaataaggaa tggtattgat cttgataaaa tttttaaaat
     8521 actgtcattt tgaatataaa ggagtttgat atggagtgga ttagattaat aggaatagca
     8581 atcattgttg tgggttttat tttaaaattt gatacaattg caacagtagt cttagctggt
     8641 ttggttacag ctttagtttc aggtgtttct ctcgttgaat ttttggagat tttgggaaaa
     8701 gaatttagca atcagcgagt gctcacgatt tttatggtta ccttgcctct tgtggggctg
     8761 tcagaaacct ttggactcaa gcaacgatca atcgatttga ttcgaaagat taaaggtctg
     8821 acagttggaa acttctatac agtttatttc tttattcgag agttagctgg tttcttttca
     8881 attcgtctag gaggacaccc tcagtttgtc agacctttgg ttcaacctat gggagaagca
     8941 gctgcagagt ctcaattagg tagaaagtta acagaggttg aagatgagac aataaaagcg
     9001 cgtgcggctg cgaatgaaaa ttttggaaat ttctttgctc aaaatacgtt tgtaggtgct
     9061 gggggagtcc tcttgatagg gggaacatta gatcagttag gctatgaaag caattatgca
     9121 gggattgctt ctacatctat tattgttgct gttataacac ttattgtagt ggggatttac
     9181 aattatttat ttgataaaaa attgatatca aaaaagacta ggggaggaga acaaaaatga
     9241 cagagttggc aaagcaacta ttagagttga cctatattgt gattggttgt caatttctcc
     9301 atacagccta ttgtagttat aaagataaaa caaacccagt tcgacttggg acatctgcat
     9361 tttggactct attgtctatt acgtttatag gtggttccta tatgccaaat atgagtattg
     9421 gtattattgt aatcctatta tcgctgttaa cattgtttaa gcaagtccgt atcggaacct
     9481 tgccatcctt agatgaaatg aaagccaata ttgaatctaa caggttgaaa aataaaattt
     9541 ttattccagt tatgctgatg gcaatacttg cgttggtctt agcgcaaatg attccagaat
     9601 ttagcaagat ttcgattagc cttgccgcct tgtttgctac aatttctgtt cttgtgatta
     9661 ccaatagtca ccctaagagt ctgttatcag aaaataatcg aatgactcag caagtttcaa
     9721 caagtgggat tgttcctcaa ttattagggg ctttgggggc tatttttact gtagcaggtg
     9781 ttggtgatgt tatctctcat ctgattagcg gtattgttcc ttcagatagt cgctttatag
     9841 gagttttggc ttatgttctt ggaatggttc tattcacaat gattatggga aatgcttttg
     9901 cagcattcac cgttattaca gcaggtgttg gagttccctt tgtatttgct ctgggagcta
     9961 atccaattgt ggctggtgct cttgccatga cagcaggtta ttgtgggacc ttattgaccc
    10021 caatggctgc taattttaac gctctaccag cagcattgat ggatatgaaa gatcagaatg
    10081 gcgttataaa ggctcaagca ggtgttgctc tagtaatgat tgttattcac atattcttaa
    10141 tgtactttct cgcattttag taaaggaaaa taaaatgaaa atattggtta caggttttaa
    10201 tccttttgga ggtgaaaaga ttaatccagc tttggaggct gtaaaattat taccatctga
    10261 gattaatggg gctgaagttc gctgggtaga aattccaacg gttttttata agtcgtcaga
    10321 agttttagag gcagaaatat tacgatatca accagatgct gtactttgta ttggacaagc
    10381 aggcggcagg accggcttaa cacctgaacg agtggctatt aatcaagatg atgctcgcat
    10441 acctgataac gaaggcaatc aaccaattga tacaccgatt cgtattgatg gagcatcggc
    10501 ctattttagt agtttaccta tcaaagcgat ggtacaagct atcaaaaaac agggacttcc
    10561 ggcagttgta tccaatagtg caggaacctt tgtttgcaat catttgatgt accaagctct
    10621 ttatttagtg gataaaaaat tccctaatat gagagcaggt ttcatgcata ttccatatat
    10681 gatggaacaa gtagtaaata agccgaatac tgcaggaatg agtctatgtg atattgtaag
    10741 aggcatagag gtagctattg aagctattgt agactacaaa gataaggatt tgcagttagt
    10801 aggcggtgag actcactgat aacctaaaaa ggatagtcaa ttatgcttgt ttactaacta
    10861 ttaactatgc taaatcaatt gaggttgttt acataaaact ctatatcaga gaagcctgat
    10921 atagagtttt ttcttgctag ttttaggatt ttcttgtaaa atagaaaaag tgaagagagg
    10981 tatgaaatga gcaagaaaga taaaaaaatc gaaattcaag tagcggatgc caaagttaat
    11041 gttggtaaag acagttttga aggttataca ttgactatcg gtaaaaaagt tatcggagaa
    11101 attgccgaat tagacggaca atttgccatt ataaagaatg ggaatgtcga tagtttttat
    11161 aaaaaattgg aaaaagctgt ggaaattttg attgaaaatt ataatttagc aaaataagtc
    11221 ttgttttttt gaaattttca tgatataata gtccatgttg attgtaggag agatagcgaa
    11281 gaggctaaac gcggcggact gtaaatccgc tccttcgggt tcgggggttc gaatccctct
    11341 ctctccattt cattaatggg gtatagccaa gcggtaaggc aagggacttt gactccctca
    11401 tgcgttggtt cgaatccagc taccccagtt cttaggtaat aatcaagata aaaagcaaaa
    11461 tatcttaggg tattttattt ttataattga aagacgtgaa tgatatgaac atgtccttgc
    11521 gggtgcttag gaaaaaaatt ataagtatgt caagtttaag aaaaacttga ttgttggagg
    11581 attttttaga tgaacgaatt tgaagatttg ctaaatagcg ttagtcaagt tgagactggt
    11641 gatgttgtta gtgctgaagt attgacagtt gatgcgactc aagctaacgt tgcaatctct
    11701 ggaactggtg ttgaaggtgt cttgactctt cgcgaattga caaacgatcg tgatgcagat
    11761 atcaatgact ttgttaaagt aggagaagta ttggatgttc ttgtacttcg tcaagtagtt
    11821 ggtaaagata ctgatacagt tacatacctt gtatctaaaa aacgccttga agctcgcaaa
    11881 gcatgggaca aacttgttgg tcgcgaagaa gaagttgtta ctgttaaagg aacgcgtgcc
    11941 gttaaaggtg gactttcagt agaatttgaa ggtgttcgtg gatttatccc agcttcaatg
    12001 ttggatactc gtttcgtacg taacgctgag cgttttgtag gtcaagaatt tgatactaaa
    12061 atcaaagaag ttaacgctaa agaaaaccgc ttcatccttt cacgtcgtga agttgttgaa
    12121 gcagctactg cagcagctcg cgctgaagta ttcggtaaat tggctgttgg tgatgttgta
    12181 actggtaaag ttgctcgtat cacaagcttc ggcgctttca tcgaccttgg tggtgttgac
    12241 ggattggttc acttgactga attgtcacat gaacgtaacg tatcaccaaa atcagttgta
    12301 actgttggtg aagaaattga agtgaaaatc cttgatctta acgaagaaga aggacgtgta
    12361 tcactttcac ttaaagcaac agtaccagga ccatgggatg gcgttgagca aaaattggct
    12421 aaaggtgatg tagtagaagg aacagttaaa cgtttgactg acttcggtgc atttgttgaa
    12481 gtattgccag gtatcgatgg acttgttcac gtatcacaaa tttcacacaa acggattgaa
    12541 aatccaaaag aagctcttaa agttggtcaa gaagttcaag ttaaagttct tgaagttaac
    12601 gcagatgcag aacgcgtgtc actttctatt aaagctcttg aagaacgtcc agcccaagaa
    12661 gaaggacaaa aagaagaaaa acgtgctgct cgtccacgtc gtccaagacg tcaagaaaag
    12721 cgtgatttcg aacttccaga aacacaaaca ggattttcaa tggctgattt gtttggtgat
    12781 atcgaacttt aatcaaattg aaaattcaca aaatcctttg tttactaaac aagggatttt
    12841 tcttttgtct ctgctccttt tttgatataa tagttctatg ttaaaatcag aaaaacaatc
    12901 acgttatcaa atgttaaatg aagaattgtc cttcctattg gaaggcgaaa ccaatgtttt
    12961 ggctaatctt tccaacgcca gtgctcttat aaaatcacgt tttcctaata ccgtatttgc
    13021 aggcttttat ttgttcgatg gaaaggaatt ggttttaggt cccttccaag gaggtgtttc
    13081 ctgcatccgt attgcactag gcaagggtgt ttgtggtgag gcagctcact ttcaggaaac
    13141 tgttattgtt ggagatgtga cgacctatct caactatatt tcttgtgata gtctagctaa
    13201 aagtgaaatt gtggtgccga tgatgaagaa tggtcagtta cttggagttc tggatctgga
    13261 ttcttcagag attgaggatt acgatgctat ggatcgagat tatttggaac aatttgtcgc
    13321 tattttgctt gaaaagacaa catgggactt tacgatgttt gaggaaaaat cttaatgtat
    13381 caagcacttt atcgaaaata tagaagtcaa aacttctccc agttagttgg tcaagaagtt
    13441 gtggctaaga ctcttaaaca agcggtggag caagagaaaa taagtcacgc ttatcttttt
    13501 tctggtcctc gtggaacggg aaaaaccagt gttgctaaaa tctttgccaa ggctatgaac
    13561 tgtcccaatc aagtgggtgg cgaaccttgc aataactgct atatttgtca agcagtgacg
    13621 gacggtagtt tagaagatgt cattgaaatg gatgcagctt ctaataatgg ggtagatgaa
    13681 attcgcgaaa ttcgtgataa atctacctat gcgcctagcc ttgctcgtta taaggtttat
    13741 atcatagatg aggttcacat gctgtctaca ggggctttta atgccctcct aaagacgctg
    13801 gaagaaccaa cacagaatgt agtctttatt ttggccacta ctgaattaca caagattcct
    13861 gctactattc tatcccgtgt gcaacgtttt gagtttaaat caattaagac acaggatatt
    13921 aaggaacata ttcactatat cttagaaaaa gaaaatatca gttctgaacc agaggctgtg
    13981 gaaatcattg ccagacgggc ggaaggtgga atgcgggacg ccttgtctat tttggatcaa
    14041 gccctgagtt tgacacaggg aaatgagctg acgactgcta tctctgaaga aattactggc
    14101 actattagcc tatcagcctt ggatgattat gtggcggcct tgtctcaaca ggatgttccc
    14161 aaagctttgt cttgcttgaa tcttcttttt gacaatggta agagcatgac tcgttttgtg
    14221 accgatcttt tgcactattt aagagacttg ttaattgttc aaacaggggg agaaaatact
    14281 catcatagtt cagtctttgt agaaaatttg gcacttcctc aaaaaaatct gtttgaaatg
    14341 attcgcttag caacagtgag tttagcagat attaagtcta gtttgcagcc caagatttat
    14401 gctgaaatga tgaccgtccg tttggcggaa atcaagcccg aaccagctct atcaggagcg
    14461 gttgaaaatg aaattgctac gctgagacag gaagttgccc gtctcaaaca agagctttct
    14521 aatgtaggtg cggttcctaa acaagttgca ccagctccta gtcgaccagc tacgggcaaa
    14581 acagtctatc gtgtcgatcg caataaagtg caatctatct tacaagaggc cgtcgaaaat
    14641 cctgatttag cacgtcaaaa tctaattcgt ttgcagaatg cctggggaga ggtaattgaa
    14701 agtctaggtg ggccggacaa ggctctgcta gttggttctc aaccggttgc tgccaatgaa
    14761 caccatgcta ttcttgcttt tgagtctaac ttcaatgctg gtcaaactat gaaacgagac
    14821 aatctcaata ccatgtttgg caatatcctc agtcaggcgg caggtttttc acctgagatt
    14881 ttagctattt ccatggagga atggaaagaa gttcgcgcag ccttttcagc caaagccaaa
    14941 tcttctcaaa ctgaaaaaga agtagaagaa agcctgattc cagaaggatt tgaatttttg
    15001 gctgataaag tgaaggtaga ggaagactaa agaaagattt cgtgatacaa taagtttatg
    15061 aataaacaac aatttattat tatggcgctg tttacagctg ctgagaccta ttttttcaat
    15121 gaagcctgga tgactggccg ctatattatg gcagcctttt gggcaatttt actctttaga
    15181 aatttccgag tcagttatgt gatgggcaaa atcgttgatg tcatcgatca gcattttaat
    15241 aggaaagact agccctcagc ttccagacaa aatcaaagcc ttttaggctt ttttttgtta
    15301 tactagaaaa gtatatttat agaatttttg ctctatttct ggggaaatca gacgtttttc
    15361 tagtaagtac tgtaaaagtt ttgaaaaaga aaggaactat catgtcagta ttagagatca
    15421 aagatcttca cgttgagatt gaaggaaaag aaattttaaa aggggttaac ctgaccctga
    15481 aaacaggaga aattgccgct atcatgggac caaatggtac aggtaaatcg actctttctg
    15541 ccgctatcat gggaaatcca aactatgaag taactaaagg tgaagttttg tttgatggcg
    15601 taaacatcct tgagttggaa gtggatgagc gtgcgcgtat gggacttttc cttgctatgc
    15661 aatacccatc agaaatccct ggaattacca atgctgagtt tcttcgtgcc gctatgaatg
    15721 cgggtaaaga agatgatgag aagatttcag ttcgtgagtt tattactagg ctagatgaaa
    15781 aaatggaatt gctcaacatg aaagaagaaa tggcagagcg ttacctcaac gaaggcttct
    15841 ctggtggtga gaaaaaacgc aatgaaattc ttcaactttt gatgttggag ccaacatttg
    15901 ctcttttgga cgagattgac tcaggtcttg atattgacgc tcttaaagtt gtgtctaaag
    15961 gtgtcaatgc catgcgtggt gaaggttttg gtgctatgat catcactcac taccaacgtc
    16021 ttttgaacta tatcacacct gatgtggtac acgtgatgat ggaaggtcgt gttgtccttt
    16081 ctggtggtcc agaattggct gcgcgtttgg aacgtgaagg atacgcaaaa ttagctgaag
    16141 aacttggcta cgactacaag gaagaattgt aatttcctcg tatcttttag gagaagtaaa
    16201 tgactagaga aaatattaaa cttttttcag aaatgcacgc tgaaccaagc tggttggctg
    16261 atctccgtca aaaagctttt gacaagattg agactttgga attaccagtt attgagcgtg
    16321 tcaaattcca ccgttggaat ctgggtgatg gaacgattac agaaaatgag ccatcagcaa
    16381 atgttccaga tttcacagct ttagatcatc acttgaagtt ggtgcaagta ggaactcaaa
    16441 ctgttttcga acaaactcca gttgagttag ctgaacaggg tgttgtcttc acagactttc
    16501 actcagcttt agaagaaatt ccagagctga tcgaagaatt cttcatgtca tctgttaagt
    16561 atgatgatga caagttggcg gcttaccaca cagcttactt taacagtggt gctgtactct
    16621 atattccaga taacgtagaa atcacagagc caattgaagg aattttctac caagatagcg
    16681 atagcaatgt gccgtttaac aagcatatta tgattatcgc tggtaaaaat tctaagatta
    16741 attatctgga gcgtttagag tcacgcggtg aaggaagtgc caaagcaact gctaatatca
    16801 cagtagaagt gattgcacgt tcaggtgcgc aagtcaagtt tgctgctatc gaccgtctag
    16861 gtgaaaacgt cactgcctac attagccgtc gtggtaaatt aggcaacgat gcaagtattg
    16921 actgggctat cggtgtcatg aacgaaggaa atgtcgttgc tgattttgat agtgacttga
    16981 ttggtaatgg tagctatgct gacctcaagg ttgtagctct ttcaagtggt cgtcaggtac
    17041 aagggattga tactcgtgta actaactatg gctgcaactc tatcggaaat atcctacaac
    17101 atggggttat ccttgaaaaa gcaactttga ctttcaatgg tatcggccac atcatcaagg
    17161 gtgctaaggg agcagatgcc caacaagaga gccgtgttct catgctttca gaccaagcgc
    17221 gttcagatgc taacccaatt cttttgattg atgaaaatga tgtcactgca ggacacgcag
    17281 cgtctatcgg acaagttgat ccagaagaca tgtattacct catgagtcgt ggattggata
    17341 aggcaactgc agagcgtttg gttgttcgtg gtttccttgg atctgttatc gtggagattc
    17401 cagtcaagga agttcgtgat gaaatgattg caactatcga agagaaattg tcaaaacgct
    17461 aaggggaagc ctatgttaga tgtagaagcg attcgcaagg attttccaat tttagatcag
    17521 attgtcaatg atgaacctct ggtctatctg gacaatgctg cgacgacaca aaaaccacta
    17581 gtagttctga aagctattaa cagttactat gagcaggaca atgccaatgt tcaccgtggt
    17641 gtccatacct tagcggaacg agcgacagct tcttatgaag ctgctcgtga aaccattcgt
    17701 aagtttatta atgcaggctc tacaaaggaa gttctcttta ccagaggaac gacaaccagc
    17761 cttaactggg tggcacgctt tgctgaggaa attctcactg agggagacca ggtcttgatt
    17821 tcagtaatgg aacaccattc taatatcatt ccatggcagg aagcttgtcg aaagactgga
    17881 gcagagcttg tctatgtcta tcttaaagac ggtgccttgg atatggagga tttgcgagct
    17941 aaattgactg ataaggttaa atttgtttcc ctagctcatg cctccaatgt tcttggtgtg
    18001 gtcaatccga tcaaggaaat cactcaatta gcccaccaag ttggggcaat catggtagtg
    18061 gatggtgctc aatctacacc tcatatgaag attgatgtcc aggacttgga tctggacttt
    18121 ttcgcctttt cgggtcacaa gatggctggt ccgactggta tcggtgtcct ttacggcaaa
    18181 gaaaagtatc ttgagcaaat gtctccagta gaatttggcg gcgagatgat tgattttgtc
    18241 tacgagcaat ccgctagttg gaaggaattg ccttggaaat ttgaggctgg aacgccaaat
    18301 atggcaggag ctattggact tgcgactgca gttgattatc tggaaaagat tggtatggat
    18361 gccgttgaag ctcatgaaca ggaattgatt gcgtacgtct atccaaaact gcaggcaatt
    18421 gagggattga ccatttacgg ttctcaggat ttggctcaac gttcgggtgt tattgccttt
    18481 aacctaggtg atctccatcc tcacgatctt gcgacggctc tggattatga aggagtggct
    18541 gttcgtgctg gtcaccattg tgcgcaaccc ttgcttcagt atttggaagt cccagcatca
    18601 gctcgtgcaa gtttttatat ctataatacc aaggcagatt gcgacaaact agtcgatgcc
    18661 ctacaaaaga caaaggagtt tttcaatggc actttctaaa ctagatagcc tttatatggc
    18721 agtggtagca gaccattcga aaaatccaca tcaccaaggg aagttagaag acgctgagca
    18781 aatcagtctc aacaatccga cttgtgggga tgtcatcaac ctctctgtca agtttgatgc
    18841 agaggaccgt ttggaagata ttgcttttct aaattcagga tgcacgattt caactgcttc
    18901 tgctagtatg atgacagatg ccgttttagg aaaaaccaaa caagaaattt tagaactggc
    18961 gactattttt tctgaaatgg ttcaagggca aaaagatgag cgtcaagacc aacttggaga
    19021 cgcggcattc ttgtcaggtg ttgccaaatt ccctcaaaga atcaagtgtg caaccctagc
    19081 ttggaatgcc cttaagaaaa caattgaaaa tcaagaaaaa cagtaagaca agtttctttt
    19141 gtcttatgaa ttattagaaa tgaagaaagg atattatggc tgaagaaaga gtagaaccaa
    19201 aaccaattga ccttggtgaa tataaatttg gtttccatga cgatgtagag cctgtcttat
    19261 cgacaggaaa aggactcaac gaaggtgtta ttcgtgaatt atctgctgct aagggtgagc
    19321 ctgagtggat gttggagttc cgtttgaagt cttatgaaac cttcaaaaaa atgcccatgc
    19381 aaacttgggg agcagacttg tcagagattg actttgatga cttaatctac taccaaaaac
    19441 catctgacaa accagcccgt tcttgggatg atgtacctga aaagattaaa gaaacctttg
    19501 aacgtatcgg gattccagaa gctgaacgtg cttatttagc aggggcttct gcccagtacg
    19561 agtcagaagt ggtttaccac aacatgaagg aagagttcca aaaattaggt attatcttta
    19621 cagatacaga ttccgcactc aaggaatacc cagacttatt taaacaatac tttgcgaagt
    19681 tggtaccgcc gacagataac aagttggcag ccctcaactc agcagtatgg tcgggtggaa
    19741 cttttatcta cgtgccaaaa ggtgtcaagg tagatattcc acttcaaact tatttccgta
    19801 tcaataacga aaatataggt cagttcgaac gtaccttgat tatcgttgat gagggagcaa
    19861 gcgtccacta cgtagaagga tgtacagcac caacatattc aagcaatagc ttgcacgctg
    19921 ccattgtaga aatttttgct ttggacggag cttatatgcg ttatacaact atccaaaact
    19981 ggtctgataa cgtctataac ttggtaacaa agcgtgctaa ggctcaaaag gatgccactg
    20041 ttgagtggat tgatggaaac ttgggtgcca aaacgactat gaaatatcca tctgtttatc
    20101 ttgatggaga aggagcgcgt ggtaccatgc tctctatcgc ctttgctaat gcagggcaac
    20161 accaagacac gggtgctaag atgattcaca atgctccaca taccagctcg tctattgtgt
    20221 ctaaatccat cgctaaaggt ggaggaaagg ttgactaccg tggacaagtc acctttaaca
    20281 agaactctaa gaaatctgtt tcccacattg aatgtgatac cattatcatg gatgacttgt
    20341 cagcatcaga tactattcca tttaatgaaa ttcacaactc gcaagtggct ttggaacacg
    20401 aagccaaagt atctaagatt tcagaagagc aattgtatta tctcatgagc cgtggattgt
    20461 cagaatctga ggcaactgaa atgattgtca tgggatttgt agaacccttt acaaaagaac
    20521 ttccaatgga atacgcagtt gagctgaacc gcttgattag ctatgaaatg gagggatcag
    20581 ttggataaaa tttgatttta tactcttcga aaatctcttc aaaccacgtc agcatcgcct
    20641 taccgtatgt atggttactg acttcgtcag tttcatctac aacctcaaaa cagtgttttg
    20701 agcaacctgc ggctagcttc ctagtttatt ctttgatttt gagtattaga tttactcaaa
    20761 atcaaggatt ttgaagatga acttgtatca aaaaatcgcg gtttaaaatc gcgatttttt
    20821 ataatttctc gttaacaaag cggacaaact gattccacca aacttttaag aagaaggctt
    20881 tttcaatttt cttgtctgct accatttcga aactagggcg ctctgtggtg atgtaacctt
    20941 gaccaatcaa gtccttgtct tcataagtca aatggccaac cactgttcca gcttcaagtg
    21001 gtgctgggat tgctttggaa tcaggtgtga attgaacaga ttgggaagat tgattcccaa
    21061 cacgttcgat tagatagata tcctctggag ccactgcagt tactgtatct tcttttccat
    21121 cttgtacagg ggctttgcta tcttgatagg catcgccttg ttgaacgatt ttgcgaagtg
    21181 taaatgtaga agaaatataa tccattaggg aagatgtagc tgtaaatcga gcgtaaggat
    21241 tattgtcttg atgatctgca tttaaaacaa ctgtgatgac tctcatgcct ttttcgacag
    21301 tagtaccaac aaaagactct ccagccttat ctgttgttcc tgtttttagc ccatcaaaac
    21361 caccacggta agcaggcata ccttctaaca tgtagttggt tgaagtgatt gtcatcccag
    21421 caaaagtaga agaaggtttt ttggtgattt ctaagacttg tgggtatttt ttgatgaggt
    21481 tgcgagcaac gatagcgaca tcataagcac taagcttatt ttcctcatct tttttagaac
    21541 ctgggtaaat gttatcccct agagtttcat tgttaagacc tgtcgtattg acaacagtgg
    21601 catcctgaat tccccattcc aagagttttg cccgcatcat atcgatgaaa tctttttctg
    21661 agccagcaat tttctcagct agggcaatag cggcgctgtt ggcactagat accagagttg
    21721 cttcaagcaa ctcttcgaca gtataattac gggcctccat aggaatatta ctggcttcag
    21781 aatttgtcgt caattgataa ggataatcag aaatatctac aggagtggag agggtaatac
    21841 ttccgttttc caaagcttca tagaccagat aagcagtaat caattttgtt atggaagcaa
    21901 tttcgacagg ttgcgttgca tccttctcat agagaatttt accagtattt gcctcaacag
    21961 caatcgcatg tttagcggca atggtaaaat cttgagcaac agcagtagaa gcacccccta
    22021 aaagagagac agttaacaaa gttaaaaata tttttttcat agtagtctta ttctatcata
    22081 aagaaaaaaa atattcttgc tttaataatt catctgttaa gctttttgaa aatatggtaa
    22141 aataaagtga gggaggtaac tcatgtttcg tagaaataaa ttattttttt ggaccacaga
    22201 aattttactc ttaaccatca tcttttacct atggagacag atggggtctt tgattaaccc
    22261 ttttgttagc gtgcttaata caattatgat tccattttta ttagggggct ttctttatta
    22321 tttgacaaac cctattgtta ctttcttaaa taaagtctgt aaactcaatc gtttgcttgg
    22381 tattttaatt accttgtgta ctttggtctg gggaatggtc ataggtgttg tctatctctt
    22441 acctattttg attaatcagt tatctagttt gattatatct agtcaaacta tttatagtcg
    22501 agtacaagac ttaatcatag acttatctaa ttatcctgcg ctccagaatt tggatgtaga
    22561 agctacaatt cagcagttaa acttatccta tgttgatatt cttcaaaata tcctaaatag
    22621 cgtatcaaat agtgtgggga gcgtcttgtc agctcttatc agtactgttt tgattttgat
    22681 tatgactcca gtttttttgg tttatttctt attagatgga cataaattct tgcccatgct
    22741 tgaaagaacg attctaaaga gggatcgctt gcatattgca ggcttattaa agaatttaaa
    22801 tgcgacgatt gctcgctata ttagtggagt ttcgattgac gcaatcatta taggttgttt
    22861 ggcttatatt ggctatagta ttattggttt aaaatatgct ttagtttttg ccattttttc
    22921 tggtgtagcc aatttaattc cttatgtggg gccaagtatt ggtttgattc ctatgatcat
    22981 cgcaaatata ttcactgatc cccatagact gctgattgca gtgatttata tgcttgttgt
    23041 tcagcaggta gatggcaata tcttatatcc tcgaatcgta ggaagtgtta tgaaggttca
    23101 tccaatcacg attttagttt tacttttgtt gtcaagcaat atctatggtg tagttggaat
    23161 gattgtcgca gtgccaacct attctatctt gaaagaaatt tctaagttct tatcccgttt
    23221 gtatgaaaat cataaaataa tgaaagaacg agaaagagaa ttagctaagt aaaagtcagg
    23281 agaaccctga tttttcttta ctggaagtgg cctttagatt agaagactga aaataagtta
    23341 aagtcttaaa ctaattttca cagctaagaa tagtagaagt taatctgata aaaatcgaaa
    23401 aaaccagtgg aattctgtgt cagggtaagt tccactggtt ttcatagtct attaaagttc
    23461 gaatgaaacc tatttatagt agattgaaac tagaatagta cacctctaat tctaaaacat
    23521 tgttagaaat cgatttgact gtcctgatct attcgttcta ttcttatttc attttactat
    23581 attttggtgc aataagtgaa aagtagtccg aataatataa ggattgattt tatagttttt
    23641 aaactcaaat gaattgaaat aaagagagta cgaaaattct catctgaaag tattttagaa
    23701 taattctctt cgtgaatttc ttcaaaacag atagcttcat cttaggtatg tgatttcttt
    23761 ttgcattttt gagttagata aggtataatg gttttattgt cttttggggt cgttacggat
    23821 tcgacaggca ttatgaggca tattttgcga ctcgtgtggc gacgtaaacg ctcagttaaa
    23881 tataactgca aaaaataaca cttcttacgc tctagctgcc taaaaaccag caggcgtgac
    23941 ccgatttgga ttgctcgtgt tcaatgacag gtcttattat tagcgagata cgattaagcc
    24001 ttgtctagcg gtttgataag agattgatag actcgcagtt tctagacttg agttatgtgt
    24061 cgaggggctg ttaaaataat acataaccta tggttgtaga caaatatgtt ggcaggtgtt
    24121 tggacgtggg ttcgactccc accggctcca ttattccttt gcattctttt gcattccttg
    24181 gtaaaacgtt gttaaatcaa cgttttttat ttttatcttt ggtattcctt tgcattcttt
    24241 tgctaaaaag ggagtcacaa acagacccta ttttaaaaaa aggatagaaa aaaggataca
    24301 acatttgtcg catcctaaaa ataatctttt ttccacggaa gacatgggat tcgaacccac
    24361 gcacgctatt acacgcctac cgcgtttcca acacggcctc ttaagcctct tgagtaatct
    24421 tccaatactt actcaaatag tctaccataa aggctcttat cttgcaataa aaattctaga
    24481 aataagaaaa atgatagatt ttgaaagaaa atgataaaaa atgcttgact tcaaaagaaa
    24541 gtatgataga atgaatagtg taaacgataa caggaggtga ttcggtgtta aaaacagagc
    24601 ggaagcaact gattttagag gagttaaatc aacatcatgt agtttctcta gaaaaattag
    24661 ttagtttgct agaaacgtca gaatcaacgg ttcgaagaga cttggatgag ttggaagcgg
    24721 aaaacaagct tcgtcgtgtg catggtggag cagaactccc ccactcctta caggaagaag
    24781 aaaccattca agaaaaatct gtcaaaaacc ttcaagaaaa gaagttgctg gctcagaaag
    24841 cagcctctct cattaaagaa aaagatgtca tctttatcga tgctggaaca acaactgctt
    24901 ttttgattca tgaattggtc aataagaata ttacagttgt gaccaactcc attcaccatg
    24961 ccgctcagtt ggttgaaaag cagattccaa ctgtcatggt tggaggaaac gtcaagacgg
    25021 cgacagatgc tagtatcggt ggcgttgctc ttaaccagat taaccaattg cactttgacc
    25081 gtgcctttat cggaatgaat ggtgttgacg atggctatta tacgactcct gatatggagg
    25141 agggagctgt gaaaagagct attttggaga atgccaagca gacctacgtc ttggtggatt
    25201 cgtcaaaaat tggacaaact tgctttgcca aggtagcacc actcaaacgc gctatcgtta
    25261 tcactagtca agggcatgag ctcttgcagg ttattaagga gaaaacggag gtaatagaag
    25321 tatgatttat acagtcacac tcaatccatc cattgactat atcgttcgtt tggaccaagt
    25381 caaagttggt agtgtaaatc gtatggacag tgatgataag tttgctggtg ggaaaggaat
    25441 caatgtcagc cgtgtcttga aacgtttgaa tataccaaat acagcgacgg gatttatcgg
    25501 tggctttact ggtaaattta tcacagatac tttagcagag gaagaaatcg agacacgttt
    25561 tgtccaggtg gcagaagata ctcgtatcaa tgttaaaatc aaagcagacc aagaaacaga
    25621 aatcaacgga acgggtccaa ctgttgaatc ggttcagcta gaagaattga aagctatttt
    25681 atctagtctg acagcagaag atacagttgt ctttgcaggt tcaagtgcta aaaatctagg
    25741 caatgttatc tataaggatt tgatttcctt gacgcgccag actggtgcgc aagtggtctg
    25801 tgactttgaa ggacagacct taattgatag tttggactac cagcctcttc ttgtaaaacc
    25861 aaacaatcat gaacttggag cgatttttgg ggttaaactc gaaagtttag atgaaattga
    25921 gaaatacgct cgtgagttac tggctaaggg tgctcaaaat gttattatct ctatggctgg
    25981 tgatggtgcc cttcttgtca catctgaggg agcttacttc gctaaaccaa tcaaaggaac
    26041 agtcaaaaat tcagttggag ctggtgattc tatggttgct ggattcacag gtgaatttgt
    26101 caaatcaaaa gacgtagtag aagccttcaa atggggagtg gcttgcggaa cggcaactac
    26161 cttctcagat gacttggcaa cggcggaatt tattaaagaa acatatggaa aagttgaggt
    26221 agaaaaacga tgaaaattca agacctattg agaaaagatg tcatgttgct agatttgcag
    26281 gcaactgaaa aaacagctgt catcgacgag atgattaaaa atttgacaga ccacggttat
    26341 gtaacagatt ttgaaacatt taaagaagga attttggcgc gtgaagcttt gacttctact
    26401 ggtttgggtg atggaatcgc aatgcctcac agcaaaaacg ctgctgtcaa agaagcgaca
    26461 gttctatttg ctaagtcaaa taagggtgtt gactacgaga gcttggatgg acaagcaact
    26521 gacctcttct tcatgattgc agctccagaa ggtgccaatg atactcactt ggcagccttg
    26581 gcagaattgt ctcaatactt gatgaaagac ggttttgcag acaaacttcg tcaagcaaca
    26641 tctgcagacc aagttatcga actttttgac caagcttcag aaaaaactga ggaacttgtt
    26701 caagcacctg ctaatgactc tggtgacttt atcgtagctg ttacagcttg tacaacaggt
    26761 attgcccaca cttacatggc ccaagaagcc cttcaaaaag tagctgctga aatgggggtt
    26821 ggtatcaagg tcgaaaccaa cggtgctagc ggtgttggaa atcaactaac tgcagaagat
    26881 atccgtaagg ctaaagctat tatcattgca gcagacaagg ccgttgaaat ggatcgattt
    26941 gatggaaaac cattgatcaa tcgtccagtt gctgacggta tccgtaagac agaagagcta
    27001 attaacttgg ctctttcagg agatactgaa gtctaccgtg ccgctaatgg tgccaaagct
    27061 gcaacagcct ctaacgaaaa acaaagcctt ggtggtgcct tgtacaaaca cttgatgagt
    27121 ggtgtatctc aaatgttacc attcgttatc ggtggtggta tcatgattgc ccttgccttc
    27181 ttgattgacg gtgctttggg tgttccaaat gaaaaccttg gcaatcttgg ttcttaccat
    27241 gagttagctt ctatgttcat gaaaattggt ggagctgcct ttggtttgat gcttccagtc
    27301 tttgcgggtt atgttgccta ctctattgct gaaaaaccgg gtttggtagc aggtttcgtg
    27361 gctggtgcta ttgccaaaga aggttttgcc tttggtaaaa ttccttatgc cgcaggtggt
    27421 gaagcaactt caactcttgc aggtgtctca tctggtttcc taggtgccct tgttggtgga
    27481 tttatcgcag gtgccttggt tcttgccatc aagaaatacg ttaaagttcc tcgttcactc
    27541 gaaggtgcta aatcaatcct tctattgcca cttcttggaa caatcttgac aggatttgtt
    27601 atgctagctg tgaatatccc aatggctgca atcaacactg ctatgaatga cttcctaggc
    27661 ggtcttggag gaggttcagc tgtccttctt ggtatcgtcc ttggtggaat gatggctgtt
    27721 gacatgggtg gaccagttaa taaagcagct tatgtctttg gtacaggtac gcttgcagca
    27781 actgtttctt caggtggttc tgtagccatg gcagcagtta tggctggagg aatggtgcca
    27841 ccacttgcaa tctttgtcgc aactcttctt ttcaaagata aatttactaa ggaagaacgt
    27901 aactctggtt tgacaaacat catcatgggc ttgtcattta tcactgaggg agcgattcca
    27961 tttggtgccg ctgacccagc tcgtgcgatt ccaagcttca tccttggttc agcagtagca
    28021 ggtggactcg ttggtcttac tggtatcaaa ctcatggcgc cacacggagg aatcttcgtt
    28081 atcgccctta cttcaaatgc tctcctttac ctcgtttctg tcttggtagg agcaatcgta
    28141 agtggtgtgg tttatggtta cctacgcaaa ccacaagcat aaaaaataga aaaatgaaaa
    28201 gattggaccg tttggtgcag tctttttctc ttcccgaaat gcctgtgaaa tatggtataa
    28261 tagaagaatg gcaaacaaga atacaagtac aacaagacgg agaccgtcta aagcagaact
    28321 ggaaagaaaa gaagcgattc aacgaatgtt gatttcgtta ggaattgcga ttttattgat
    28381 tttcgcagcc ttcaaattag gggctgcagg tataaccctt tataatttaa ttcgcttgct
    28441 agtgggtagc ctagcttatc tggcgatatt cggcctatta atctatctct tctttttcaa
    28501 gtggatacga aaacaggaag gactcttatc tggctttttc accatatttg ctggcttact
    28561 cttgattttt gaggcctact tggtttggaa atatggtttg gacaagtccg ttctaaaagg
    28621 gaccatggct caggttgtga cagatctgac tggttttcga acgactagct ttgctggagg
    28681 gggcttgatc ggggtcgctc tttatattcc aacagccttt ctcttttcaa atatcggaac
    28741 ttactttatt ggttctatct tgattttagt gggttctctc ctagtcagcc cttggtctgt
    28801 ttacgatatt gctgaatttt tcagtagagg ctttgccaaa tggtgggaag ggcacgagcg
    28861 tcgaaaagag gaacgctttg tcaaacaaga agaaaaagct cgccaaaagg ctgagaaaga
    28921 ggctagatta gaacaagaag agactgaaaa agccttactc gatttgcctc ctgttgatat
    28981 ggaaacgggt gaaattctga cagaggaagc tgttcaaaat cttccaccta ttccagaaga
    29041 aaagtgggtg gaaccagaaa tcatcctgcc tcaagctgaa cttaaattcc ctgaacagga
    29101 agatgactca gatgacgaag atgttcaggt cgatttttca gccaaagaag cccttgaata
    29161 caaacttcca agcttacaac tctttgcacc agataaacca aaagatcagt ctaaagagaa
    29221 gaaaattgtc agagaaaata tcaaaatctt agaagcaacc tttgctagct ttggtattaa
    29281 ggtaacagtt gaacgggccg aaattgggcc atcagtgacc aagtatgaag tcaagccggc
    29341 tgttggtgta agggtcaacc gcatttccaa tctatcagat gacctcgctc tagccttggc
    29401 tgccaaagat gtccggattg aagcaccaat ccctgggaaa tccctaatcg gaattgaagt
    29461 gcccaactcc gatattgcca ctgtatcttt ccgagaacta tgggaacaat cgcaaacgaa
    29521 agcagaaaat ttcttggaaa ttcctttagg gaaggctgtt aatggaaccg caagagcttt
    29581 tgacctttct aaaatgcccc acttgctagt tgcaggttca acgggttcag ggaagtcagt
    29641 agcagttaac ggcattattg ctagcattct catgaaggcg agaccagatc aagttaaatt
    29701 tatgatggtc gatcccaaga tggttgagtt atctgtttac aatgatattc cccacctctt
    29761 gattccagtc gtgaccaatc cacgcaaagc cagcaaggct ctgcaaaagg ttgtggatga
    29821 aatggaaaac cgttatgaac tctttgccaa ggtgggagtt cggaatattg caggttttaa
    29881 tgccaaggta gaagagttca attcccagtc tgagtacaag caaattccgc taccattcat
    29941 tgtcgtgatt gtggatgagt tggctgacct catgatggtg gccagcaagg aagtggaaga
    30001 tgctatcatc cgtcttgggc agaaggcgcg tgctgcaggt atccacatga ttcttgcaac
    30061 tcagcgtcca tctgttgatg tcatctctgg tttgattaag gccaatgttc catctcgtgt
    30121 agcatttgcg gtttcatcag gaacagactc ccgtacgatt ttggatgaaa atggagcaga
    30181 aaaacttctt ggtcgaggag acatgctctt taaaccgatt gatgaaaatc atccagttcg
    30241 tctccaaggc tcctttatct cggatgacga tgttgagcgc attgtgaact tcatcaagac
    30301 tcaggcagat gcagactacg atgagagttt tgatccaggt gaggtttctg aaaatgaagg
    30361 agaattttcg gatggagatg ctggtggtga tccgcttttt gaagaagcta agtctttggt
    30421 tatcgaaaca cagaaagcca gtgcgtctat gattcagcgt cgtttatcag ttggatttaa
    30481 ccgtgcgacc cgtctcatgg aagaactgga gatagcaggt gtcatcggtc cagctgaagg
    30541 taccaaacct cgaaaagtgt tacaacaata aaaaaatagc ttctttccaa gtttggaggg
    30601 aagctatttt agtggctatt gattgctttt attttctgaa gttggcgcat tggactgttt
    30661 ttcgttttca gtagcaggtt tacttgaagc aggagtagaa gagtcctgag ttgctgtttt
    30721 ctgatcttct tttttctctt ccttgacgct agattttggt gtttcctctt gctgtgtttt
    30781 ttcttgacta gtgttagtct ctttagttgg actggtgttt tccttagggg attccttttg
    30841 gatttctttg acaatggttg tcgtctggct tgtcgtaggt tcttttttaa tatttttgtt
    30901 attatccaag gcgttcataa tcgtgatact tgcggtaatc aagccaagga tactagcgat
    30961 tgtagcaacg gttttttgaa agactgtaaa gccttttttg atgtgttctg tttttggttt
    31021 tgaagttcta cgatagttag acatacattc tctcctttga ttatgattta ttatactctg
    31081 tttctttaaa aaaatcttaa aaaaagagaa atttcccttt cttgtcgcaa gctccgtttc
    31141 atgatacaat agaggaagtg attttagaaa gcgtgagaaa catgatttac tttgataatt
    31201 cagcgacgac caagccttat cctgaagccc ttgaaaccta tatgcaggtc gcttcaaaaa
    31261 ttttaggaaa cccatctagt ctccatcgtt tgggagacca agcaacacga atcttagatg
    31321 cttctcgcca acagattgca gatttaatcg gtaagaaaag cgatgaaatc ttctttacct
    31381 cgggtggaac agaaggggat aactggctta tcaagggtgt ggcctttgaa aaagctcagt
    31441 ttggcaagca catcattgtt tcagccattg aacatccagc agtcaaagag tcagccctct
    31501 ggttgaaaag tcaaggattt gaagtggatt ttgctccagt tgataagaaa ggcttggtcg
    31561 atgttgaggc gttagcaggt ttgatacggc atgatacaat cctcgtttcc atcatggctg
    31621 tgaacaatga aatcggctct atccaaccta ttgaggctat ttcagaattc ttggcagaca
    31681 agccgactat ttccttccac gttgatgcgg ttcaggcgct tgccaaaatt ccgactgaaa
    31741 agtatctgac agaacgggtg gattgcgcga ctttctctag tcacaagttc cacggggttc
    31801 gaggtgttgg ctttgtctat atcaaatctg gcaagaagat tacacctctt cttacaggtg
    31861 gtggccagga gcgagattat cgttcgacaa ctgaaaatgt ggcagggatt gcagcgacag
    31921 ccaaggccct ccgtttgtct atggaaaagc tagatatctt taggagcaag actgggcaga
    31981 tgaaggcagt gattcgccaa gctcttctga actatccgga tatttttgtc ttttcagatg
    32041 aggaaaactt tgcacctcat attctgactt ttggaatcaa aggtgttcga ggtgaagtca
    32101 tcgttcacgc ctttgaagac tatgatattt tcatctcaac aacctcagct tgttcatcta
    32161 aggcaggaaa accagccggt accttgattg ccatgggagt ggacaaagat aaggccaagt
    32221 cagctgtgcg tcttagccta gacttggaaa atgatatgag tcaggtcgag cagtttttga
    32281 ccaagttaaa attgatttac aatcaaacta gaaaagtaag ataggagcat tcatgcagta
    32341 ttcagaaatt atgattcgct acggagagtt gtcaaccaag ggtaaaaacc gtatgcgttt
    32401 catcaataaa cttcgtaata atatttcgga cgttttgtct atctataccc aagttaaggt
    32461 aacagcagat cgcgaccgtg cccacgctta cctcaatgga gctgattaca cagcagttgc
    32521 agaatctctc aaacaagttt ttggaattca aaacttttct cctgtttata aggttgaaaa
    32581 atctgtagaa gttttgaagt cttctgtcca agagattatg cgggacatct acaaggaagg
    32641 tatgaccttt aagatttcta gcaagcgtag cgaccacaac tttgaacttg atagtcgtga
    32701 actcaaccaa acacttggag gggctgtatt cgaagccatt ccaaatgtgc aagttcaaat
    32761 gaaaagtcct gacatcaatc ttcaggtgga gattcgtgaa gaagcagcct atctttctta
    32821 tgaaaccatt cgtggggctg gtggtttgcc agttggaact tcaggtaaag ggatgctcat
    32881 gttgtcagga gggattgact cacctgtagc aggttatctt gctcttaagc gtggggtgga
    32941 tatcgaggca gttcactttg ctagtccacc atatactagt cctggtgccc tcaagaaagc
    33001 gcaggacttg acccgtaaat tgaccaagtt tggcggaaat atccagttta tagaggtgcc
    33061 tttcacagag attcaagagg aaatcaaagc caaagcgcca gaagcttatt tgatgactct
    33121 aactcgtcgc tttatgatgc ggattactga ccgtattcgt gaggtacgaa atggtttggt
    33181 tatcatcaat ggggaaagtc taggtcaagt agccagccaa acccttgaaa gtatgaaggc
    33241 tatcaatgct gttaccaaca ctcccatcat tcgtcctgtg gttaccatgg acaagttgga
    33301 aatcattgac atcgcccagg aaatcgatac ctttgacatt tcaatccaac cgtttgaaga
    33361 ctgttgtacc atttttgcac cagatcgtcc aaaaacaaat cctaaaatta agaatgcgga
    33421 gcagtacgaa gcgcgtatgg atgttgaagg cttggttgag cgagcagtgg ctggaatcat
    33481 gattactgaa atcacacctc aagccgaaaa agatgaagtt gatgacttga ttgacaatct
    33541 gctctaattc agaaaatcca aaagaatagc gaaaatcagt aaaaaaagtt agttttttct
    33601 ctaaaaacag gtaaaaaact aacttttttt atttttatga tataatgata taaaattttg
    33661 aatatagaga gttttctgac aatgaatcaa tcctactttt atctaaaaat gaaagaacac
    33721 aaactcaagg ttccttatac aggtaaggag cgccgtgtac gtattcttct tcctaaagat
    33781 tatgagaaag atacagaccg ttcctatcct gttgtatact ttcatgacgg gcaaaatgtt
    33841 tttaatagca aagagtcttt cattggacat tcatggaaga ttatcccagc tatcaaacga
    33901 aatccggata tcagtcgcat gattgtcgtt gctattgaca atgatggtat ggggcggatg
    33961 aatgagtatg cggcttggaa gttccaagaa tctcctatcc cagggcagca gtttggtggt
    34021 aagggtgtgg agtatgctga gtttgtcatg gaggtggtca agccttttat cgatgagacc
    34081 tatcgtacaa aagcagactg ccagcatacg gctatgattg gttcctcact aggaggcaat
    34141 attacccagt ttatcggttt ggaataccaa gaccaaattg gttgcttggg cgttttttca
    34201 tctgcaaact ggctccacca agaagccttt aaccgctatt tcgagtgcca gaaactatcg
    34261 cctgaccagc gcatcttcat ctatgtagga acagaagaag cagatgatac agacaagacc
    34321 ttgatggatg gcaatatcaa acaagcctat atcgactcgt cgctttgcta ttaccatgat
    34381 ttgatagcag ggggagtaca tctggataat cttgtgctaa aagttcagtc tggtgccatc
    34441 catagtgaaa tcccttggtc agaaaatcta ccagattgtc tgagattttt tgcagaaaaa
    34501 tggtaagtta agaaaggaaa aaacgaaatg catattgaac atcttagcca ctggagtggt
    34561 catcttaacc gtgaaatgta ccttaaccgt tatggacatg gtgggattcc agttgtggtc
    34621 tttgcttcat caggtggtag tcacaacgaa tactatgatt ttggcatgat tgatgcctgt
    34681 gcttccttta tcgaggaagg ccttgtccag ttctttaccc tatctagttt ggatagtgag
    34741 agctggttgg ctacttggaa aaatgctcat gaccaagcgg aaatgcaccg tgcctacgaa
    34801 cgttatgtga ttgaggaggc cattctttta tcaagcacaa gacaggttgg tttgatggca
    34861 tgatgacgac aggttgctct atgggagcct atcatgcact caatttcttc ctccagcatc
    34921 cagatgtctt taccaaagtg attgctctca gtggtgttta cgacgcacgt ttctttgtcg
    34981 gtgattacta caacgatgat gctatttacc aaaactcgcc agtagattat atttggaacc
    35041 aaaacgacgg ctggtttatt gaccgttacc gtcaggcaga gattgtgctg tgtacggggc
    35101 ttggagcctg ggaacaagat ggtttgccat ccttttacaa gctcaaagaa gcctttgaca
    35161 agaaacaaat tccagcctgg tttgctgaat ggggacatga tgtcgcccat gactgggaat
    35221 ggtggcgtaa acaaatgcct tatttcctcg gtaatctcta tttataaaag gagttaccta
    35281 tgaattacct tgttatttct ccctactatc cacaaaactt tcaacagttt accatcgaac
    35341 tagctaataa aggcatcaca gtcttgggaa ttggtcaaga gtcttacgag caattggatg
    35401 agcccttgcg caatagcttg accgagtatt ttcgtgttga taatcttgag aacatagatg
    35461 aagtcaaacg tgcagttgct tttctctttt ataaacatgg tccaattggc cgcatcgagt
    35521 ctcacaatga atactggctt gagctagacg caacactcag agaacaattc aatgtttttg
    35581 gtgccaaacc agaggatctc aaaaagacga aatataagtc tgaaatgaag aaacttttca
    35641 aaaaagcagg tgttcctgtg gtacctggag ctgttatcaa gacggaagca gatgttgatc
    35701 aagcagtgaa agaaatcggt cttccaatga ttgccaaacc tgataatgga gtgggagcag
    35761 ccgcaacctt taaacttgag acagaagacg atatcaatca cttcaagcaa gaatgggacc
    35821 attcaaccct ttatttcttt gaaaaatttg tcacttccag cgaaatctgt acctttgacg
    35881 ggctcgtgga caaggatgga aagattgtct tctcaacaac ctttgactac gcctatacac
    35941 cgcttgacct catgatttat aagatggaca attcttatta tgtgctcaag gatatggatc
    36001 ctaaactgcg caagtatggg gaagcaattg tcaaagaatt tggtatgaaa gaacggtttt
    36061 tccatattga gttcttccgt gagggggacg attatattac catcgagtac aataaccgcc
    36121 ctgcaggtgg ttttaccatt gatgtttata actttgctca ttccttggac ctttatcgtg
    36181 gctatgcagc tattgtcgca ggagaggagt tcccggcgtc agactttgaa actcagtatt
    36241 gtttggctac ttctcgccgt gcaaatgctc actatgttta ttcagaagag gatttgcttg
    36301 ccaaatatag ccagcagttc aaggttaaaa aagtcatgcc agctgccttc gcggaacttc
    36361 aaggagatta cctgtatatg ctgaccactc cgagtcgaca agaaatggag cagatgattg
    36421 cagatttcgg acaacgtcaa gaataagaac tatcggatta aggaaattaa ctcccttaat
    36481 ccttttgttt tgtctgataa aaaataagag catcccaaca aggtagctat cataaaactt
    36541 gttcgataac tatttgaagc aggattaggt ggtcagaaat taaattttaa tatttcaatt
    36601 gagtcatagt attgtgtttg cgtatcctta aatcagctaa aaggatccat gacgacacct
    36661 atacgatata gttttcaaga taccaaacaa gtctattaat attcaatgaa aatcaaagag
    36721 caaactagga agctagccgc aggtttctca aaacactgtt ttgaggttgt ggatagaact
    36781 gacagagtca gtatcatata cctacggcaa ggtgaagctg acgtggtttg aagagatttt
    36841 cgaagagtat aaaatattca ggtgacgcat agatatagtt aattgaagct ttgtttgaaa
    36901 tctgataaaa taatgatatt actaagtttt aaaaactaaa gaaaagggaa gatatgatta
    36961 caggcgaatt aaaaaataaa atcgatcagc tgtgggaaat tctttggaca gaaggaaacg
    37021 caaatccttt aacaaatatt gaacagttga cttatctctt atttatgaaa gatttggata
    37081 gtgtcgagct tggacgtgaa agtgatgctg aatttctagg gattccttat gagggagttt
    37141 ttccaaaaga taaacctgaa taccgttggt caacttttaa aaatatagga gatgctcagg
    37201 aagtttatcg tttaatgact caggagattt ttccgtttat taaaaatctc aagggggata
    37261 cagatgatac agccttttca cgatatatgc gagaagctat ttttcaaata aataaacctg
    37321 ctacgcttca aaaggcaatt tctatcttag atgtttttcc aactagggga ttagatgtag
    37381 attttgataa tgacaaacaa agtattactg atatcggaga tatctatgaa tatctgttat
    37441 caaaattgtc gaccgcaggt aaaaatggac agttccgtac acctcgtcac atcatcgata
    37501 tgatggttga gttgatgcaa ccgactatca aagatatcat ctcagatccc gctatgggtt
    37561 ctgctggctt cttagtatct gctagccgtt acttaaagcg taagaaagat gaatgggaaa
    37621 ccaatacaga taatatcaat cattttcata atcagatgtt tcatggaaat gatacggata
    37681 cgactatgtt gagacttggg gcgatgaaca tgatgctaca tggagtagaa aatccacaaa
    37741 tcagttacct tgactcgctg tctcaagata atgaagaagc cgataaatat actttggttt
    37801 tagcaaatcc tccttttaag ggctcacttg actacaattc aacctctaat gaccttcttg
    37861 caaccgtaaa aaccaaaaaa acagaattac tctttctttc tcttttcttg cgaactttaa
    37921 aaccaggtgg acgagcagca gttatcgtac ctgatggtgt cctttttggt tcgtctaaag
    37981 ctcataaagg aattcgtcag gaaattgtag agaatcataa gcttgatgct gtaatctcaa
    38041 tgcctagtgg tgtgttcaag ccttatgctg gagtttcaac tgccattctc atctttacaa
    38101 aaactggtaa tggtggtact gacaaagtct ggttttacga tatgaaagcg gatggtttaa
    38161 gtttggatga taagcgacaa ccgattagcg acaatgatat tccagatatt atcgaacgct
    38221 ttcatcatct tgaaaaagaa gcagaacgtc agagaacgga tcaatctttc tttgttccag
    38281 ttgctgagat aaaggaaaat gattatgatt tgtctatcaa taaatataaa gagattgagt
    38341 atgaaaaagt tgagtatgaa ccaacagagg tcatcttaaa gaaaatcaat gatttagaaa
    38401 aagaaattca agctggcttg gctgaattag aaaaattact caagtagaga ggtggctgta
    38461 tgaaaaaagt gaagttgggg gaagtcttat ctctaaaaaa aggcaagaaa gccactgtac
    38521 ttgctgaaca aacaactcta agccaacgtt atattcaaat agatgattta agaaataata
    38581 ataatttaaa attcactgaa agtttaaata tgactgaagc actcccagat gatattctga
    38641 tagcatggga tggagctaat gcaggaacag ttggttatgg attatcggga gctgttggta
    38701 gtacaattac ggtcttaaaa aagaatgagc gatacaaaga aaaaattata tcagattact
    38761 tgggagtctt tttggaaagt aaatcgcagt atttacgaga acattcaaca ggtgcaacaa
    38821 ttcctcattt aaacaagaat atattacttg atttacaatt agaattgcta ggtatcgaag
    38881 aacaagagaa cattatctgt attcttaata cgattaaaag gcttattact aaaagaaaat
    38941 tgcagttaga tgaactaaac ttgctcgtca aatcccgatt taacgagatg tttggggatg
    39001 ttattctaaa tgaaaaagaa tggaaagtta gcaaatggaa cgagattcta acaataagaa
    39061 atggtaaaaa tcaaaaacag gttgaagatg ctgatgggaa atttcctatt tatggaagtg
    39121 ggggaattat gggatatgct aaagattgga tagtgaagaa aaattcagtt attattggac
    39181 gtaaaggaaa tataaataaa cctattttag ttagagaaaa tttttggaat gtagatacag
    39241 catttggatt agagcctgtt ttagaaaaaa taaactcaga atatttattc tatttttgtc
    39301 aattatacaa ttttgagaag ttaaataagg ctgtaacaat acctagttta actaaatcag
    39361 atttattaaa tatttccatc cccctccccc cactagccct ccaaaatgag ttcgcagact
    39421 ttgtagccct ggtcgacaaa tcacaatttg cttgtgagat agctataaaa gtgtggagaa
    39481 atagcttgaa atttagtata atatagctaa actatttgtt taaagtgaga aaaaaatggg
    39541 aaattttagc tttcttttaa aaaatgacga atatgaatct ttttcaaaac cttgcattga
    39601 agctgagaat atgattgcta catcaactgt ggctactgcc tttatggcgc gtcgtgcttt
    39661 agagcaggct gtccattgga tatatagtca cgattcatat ttagaagctc cctatcgtgc
    39721 tactctatct tctttagtat gggatgatga ttttagggat atcgtagatt ctgaactcca
    39781 caagcagata gttctgttga ttcggtgggg aaaccatgct gctcatggtg gtgaaattaa
    39841 ggaacgagaa gcgattttag ctttgcatca tttgtatcag tttgttaatt ttatcgatta
    39901 ttgttacagc aatgagtttg tggagcgtta ttttgatgag aagtgcttac cactttcagc
    39961 aaacatcaaa taccgagaaa ctccacaatc tatgataaag ttacaagaca gtttaccaga
    40021 actgcctgat tttcatgaac agatggctgc tcagtccgta gaagttcaag agacttatac
    40081 tgaaaaacgt gagactgcag cgcaacggca agatgtgcct ttccatattg atcaattatc
    40141 tgaggcagag acaagaaagc tctttattga tatcgatctc cgtttagcag gatggatatt
    40201 tgaagaaaac tgtcgtgttg agatagccgt tgatggtctc aagcacggtt caggaattgg
    40261 ttactgtgac tatgtacttt atggtaaaaa tgggaaaatt ttagcgattg tggaggctaa
    40321 aaaagcctct gtcaatccag aagtagggga agtacaggtc aaagaatatg ctgaagcttt
    40381 ggagaaacat atcggctatc agccaatttg ctttattaca aatgggttga agcactatat
    40441 acttgatggt ccgaaccgcc gccagattgc aggcttttac tctcaagaag aattgcaatt
    40501 agtgatggat agacgtcatc ttcaaaaacc gcttgaggat atttctagta aaattaggga
    40561 cgatatttcc gggcgtcact accaaaaaca tgccattgca agcgtttgtg aagctttctc
    40621 tgatcatcgt agacaggcac ttttggttat ggcaactggg gcggggaaaa ctcgtacagc
    40681 agtttctcta gttgatatct tatcacgtca taactgggta aaaaacgttc tcttcttagc
    40741 cgatagaact tccttggtta agcaagcata tgattcgttt agaaaattac tcccagatct
    40801 ttccgtttgt aacttcttag aagataaaga aggagctcaa tcaagtcgaa tggtcttttc
    40861 aacttatccg accatgattg gagcgattag tggtcaagaa gaagtaaatc aacgcccttt
    40921 tactgttggg cattttgacc ttatcataat tgacgaatct caccgttcta tttatcagaa
    40981 atacaagtcc atttttgatt attttgatgc aaggattgta ggcttaacag ctactccgcg
    41041 tcaagattta gataaaaaca cctatggatt ctttaatttg gagaatgggg ttccaacata
    41101 tgcatatgat ttggaagagg ctgttaaaga cggatattta gtagcctatc attctatcga
    41161 aaccaaactg aaactaccta cggatggtct acattatgat gatttgtccg aagaagaaaa
    41221 ggaacatttt gatagcaaat ttgaagacga tagctgtgaa aaagatattg atgggagtgt
    41281 gtttaattcc tttattttca ataaaagtac agtagaaatt gttttaaatg aactcatgac
    41341 aagaggaatt cagacagcct cgggtgatga aattggtaaa actattattt ttgctaaaaa
    41401 tcatgaccat gcggaatata tcagaggtat ttttaacaac cgctatcctg aaaaagggag
    41461 cgactatgct caggtgattg attatagtat taagcattat cagaccttga ttgatgattt
    41521 taaaattaag gagaagtatc ctcaaattgc gatttctgtc gatatgttag atacaggtat
    41581 tgatgtacca gaggttgtta atttagtctt cttcaagaaa gtacgctcta aaactaagtt
    41641 ttggcagatg attggtcgag gaacccgtct atgtaaagat ttatttggac ctgagcagga
    41701 taaggaaaac ttcttggtat ttgattatgg ggacaatttt gattattttc gtgcagatcc
    41761 aagagatgga gagggtcgtc acattgtttc gctgactcag cgtttattta atatcaaagt
    41821 ggacttgatt cgagaacttc agggactcca ataccaagaa gatcagtttg cgagagcata
    41881 ccgtcagcag cttgtctcgg aacttcaagg tcgtatagag agcttaaatg agttggactt
    41941 cagggttcgt atggttttag atacagttta tagctatagg aaattggaaa gttggcagaa
    42001 tctaactgct gttacaagtg aaaccattca aaaaaatctc tctccgcttt tatttgatga
    42061 agataaagaa gatgagatgg cgaggagatt tgatttgtgg ttgcttcata ttcagttggg
    42121 gcaactgaca gctaaatctt ccactgttca tatttcccaa gtgatgaaga cggctagagc
    42181 tctttctgct attggcaata tcccgcaggt ttttgagcag gctgaaatta tggctctttg
    42241 tcaactgtag tgggttgaaa aaaagctaag cttgagaaag gacaaatttt gtcctttctt
    42301 ttttgatatt cagggcgata aaaatccgtt ttttgaagtt ttcaaagttc cgaaaaccaa
    42361 aggcattgcg cttgataagt ttgatgagat tattggtcgc ttccagtttg gcattagaat
    42421 agtgtagttg aagggcgttg acgattttct ctttgttctt tagaaaggtt ttaaagacag
    42481 tctgaaaaag aggatgaacc tgcttcagat tgtcctcaat gagtccgaaa aatttctcag
    42541 ggtctttgtt ctgaaagtga aaaagtaaga gttgatagat ctgatagtgg tgtttcaagt
    42601 cttctgaata gcttaaaatc ttgtcaagaa tttctttatt tgttaagtgc atgcgaaaag
    42661 tagggcgata aaaacgttta tcgctcaatt tacgactatc ctgttggatg agtttccagt
    42721 aacgcttgat agccttgtat tcatgagatt ttcgttcaaa ctgattcata atttgaacac
    42781 gaaaacgact catggcacgg ctgagatgtt ggataatatg gaaacgatct agaacgattt
    42841 tagcacacgg aaaaagctgt ttagccaagt catagtaagg actaaacata tccatcgtaa
    42901 tgattttcac ttgacaacga acggctctat cgtagcgaag aaagtgattt cggatgacag
    42961 cttgtgttct gccttcaaga acagtgataa tattaagatt atcaaaatct tgcgcaatga
    43021 aactcatctt tcccttagtg aaggcatact catcccaaga cataatcttt ggaagccgag
    43081 aaaaatcatg ctcaaagtga aagtcattga gcttgcgaat gacagttgaa gttgaaatgg
    43141 ccagctgatg
//
LOCUS       DAVBBO010000013        39608 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ST1
            SAMEA2066453-rid20184263.denovo.013, whole genome shotgun sequence.
ACCESSION   DAVBBO010000013 DAVBBO010000000
VERSION     DAVBBO010000013.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2066453
            Sequence Read Archive: ERR351777
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 39608)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 39608)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980402.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980402.1
            Genome Coverage       :: 176x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:17:33
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,141
            CDSs (total)                      :: 2,104
            Genes (coding)                    :: 1,953
            CDSs (with protein)               :: 1,953
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 16S)
            partial rRNAs                     :: 1 (23S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 151
            CDSs (without protein)            :: 151
            Pseudo Genes (ambiguous residues) :: 0 of 151
            Pseudo Genes (frameshifted)       :: 73 of 151
            Pseudo Genes (incomplete)         :: 76 of 151
            Pseudo Genes (internal stop)      :: 40 of 151
            Pseudo Genes (multiple problems)  :: 32 of 151
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..39608
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2066453-rid20184263.denovo.013"
                     /strain="ST1"
                     /db_xref="taxon:1313"
     gene            470..1591
                     /gene="mnmA"
                     /locus_tag="VQU30_000669"
     CDS             470..1591
                     /gene="mnmA"
                     /locus_tag="VQU30_000669"
                     /EC_number="2.8.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006153390.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA 2-thiouridine(34) synthase MnmA"
                     /protein_id="HET2446821.1"
                     /translation="MSDNSKTRVVVGMSGGVDSSVTALLLKEQGYDVIGIFMKNWDDT
                     DENGVCTATEDYKDVVAVADQIGIPYYSVNFEKEYWDRVFEYFLAEYRAGRTPNPDVM
                     CNKEIKFKAFLDYAMTLGADYVATGHYARVARDEDGTVHMLRGVDNGKDQTYFLSQLS
                     QEQLQKTMFPLGHLEKPEVRRLAEEAGLSTAKKKDSTGICFIGEKNFKNFLSNYLPAQ
                     PGRMMTVDGRDMGEHAGLMYYTIGQRGGLGIGGQHGGDNAPWFVVGKDLSKNILYVGQ
                     GFYHDSLMSTSLEASQVHFTREMPEEFTLECTAKFRYRQPDSKVTVHVKGDKAEVIFA
                     EPQRAITPGQAVVFYDGEECLGGGLIDNAYRDGQVCQYI"
     gene            1732..2187
                     /locus_tag="VQU30_000670"
     CDS             1732..2187
                     /locus_tag="VQU30_000670"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HET2446822.1"
                     /translation="MTQQDFRTKVDNTVFGVRATALIVQNHKLLVTKDKGKYYTIGGA
                     IQVNESTEDAVVREVKEELDVKAQAGQLAFVVENRFEVDGVSYHNIEFHYLVDLLEDA
                     PLTMQEDEKRQPCEWIDLDKLQNIQLVPAFLKTALPDWEGQLRHIHLEE"
     gene            2197..4110
                     /gene="mnmG"
                     /locus_tag="VQU30_000671"
     CDS             2197..4110
                     /gene="mnmG"
                     /locus_tag="VQU30_000671"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000221902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA uridine-5-carboxymethylaminomethyl(34)
                     synthesis enzyme MnmG"
                     /protein_id="HET2446823.1"
                     /translation="MTYHFTEEYDIIVIGAGHAGVEASLAASRMGCKVLLATINIEML
                     AFMPCNPSIGGSAKGIVVREVDALGGEMAKTIDKTYIQMKMLNTGKGPAVRALRAQAD
                     KELYSKEMRKTVENQENLTLRQTMIDEILVEDGKVVGVRTATHQEYAAKAVIVTTGTA
                     LRGEIIIGDLKYSSGPNHSLASINLADNLKELGLEIGRFKTGTPPRVKASSINYDVTE
                     IQPGDEVPNHFSYTSRDEDYVKDQVPCWLTYTNGTSHEIIQNNLHRAPMFTGVVKGVG
                     PRYCPSIEDKIVRFADKERHQLFLEPEGRNTEEVYVQGLSTSLPEDVQRDLVHSIKGL
                     ENAEMMRTGYAIEYDMVLPHQLRATLETKKISGLFTAGQTNGTSGYEEAAGQGIIAGI
                     NAALKIQGKPELILKRSDGYIGVMIDDLVTKGTIEPYRLLTSRAEYRLILRHDNADMR
                     LTEMGREIGLVDDERWARFEIKKNQFDNEMKRLDSIKLKPVKETNAKVEEMGFKPLTD
                     AVTAKEFLRRPEVSYQDVVAFIGPAAEDLDDKIIELIETEIKYEGYISKAMDQVAKMK
                     RMEEKRIPANIDWDDIDSIATEARQKFKLINPETIGQASRISGVNPADISILMVYLEG
                     KNRSISKTLQKSK"
     gene            4299..4388
                     /locus_tag="VQU30_000672"
                     /pseudo
     CDS             4299..4388
                     /locus_tag="VQU30_000672"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820552.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopuranose mutase"
     gene            complement(4534..6213)
                     /locus_tag="VQU30_000673"
     CDS             complement(4534..6213)
                     /locus_tag="VQU30_000673"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009729634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease J"
                     /protein_id="HET2446824.1"
                     /translation="MAYTLKPEEVGVFAIGGLGEIGKNTYGIEYQDEIIIVDAGIKFP
                     EDDLLGIDYVIPDYSYIVDNIDRVKAVLITHGHEDHIGGIPFLLKQANVPIYAGPLAL
                     ALIRGKLEEHGLLRNAKLYEINHNTELTFKNLKATFFRTTHSIPEPLGIVIHTPQGKI
                     VCTGDFKFDFTPVGEPADLHRMAALGEEGVLCLLSDSTNAEVPTFTNSEKVVGQSIMK
                     IIQGIEGRIIFASFASNIFRLQQATEAAVKTGRKIAVFGRSMEKAIVNGIDLGYIKAP
                     KGTFIEPNEIKDYPAGEVLILCTGSQGEPMAALSRIANGTHRQVQLQPGDTVIFSSSP
                     IPGNTTSVNKLINIISEAGVEVIHGKVNNIHTSGHGGQQEQKLMLRLIKPKYFMPVHG
                     EYRMQKVHAGLAVDTGVEKDNIFIMSNGDVLALTADSARIAGHFNAQDIYVDGNRIGE
                     IGAAVLKDRRDLSEDGVVLAVATVDFKSQMILSGPDILSRGFVYMRESGDLIRQSQRI
                     LFNAIRIALKNKDASVQSVNGAIVNAIRPFLYENTEREPIIIPMILTPDEE"
     gene            complement(6215..6448)
                     /locus_tag="VQU30_000674"
     CDS             complement(6215..6448)
                     /locus_tag="VQU30_000674"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000639444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-dependent RNA polymerase auxiliary subunit
                     epsilon family protein"
                     /protein_id="HET2446825.1"
                     /translation="MIYKVFYQETKERSPRRETTRALYLDIDASSELEGRITARQLVE
                     ENRPEYNIEYIELLSDKLLDYEKETGAFEITEF"
     gene            6830..7051
                     /locus_tag="VQU30_000675"
     CDS             6830..7051
                     /locus_tag="VQU30_000675"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000184674.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2446826.1"
                     /translation="MTNQVLEENYLCDSLLAFSPPRDLCRLVCILLWIKCLDALLMLG
                     FFVWGCRDSRFTTRKFHPIYQDEVVFAFF"
     gene            complement(7264..7416)
                     /gene="cibB"
                     /locus_tag="VQU30_000676"
     CDS             complement(7264..7416)
                     /gene="cibB"
                     /locus_tag="VQU30_000676"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000977347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fratricide two-peptide bacteriocin subunit CibB"
                     /protein_id="HET2446827.1"
                     /translation="MMKDLNNCREISNKELQEIKGGFGVGVGIALFMAGYTIGKDLRK
                     KFGKSC"
     gene            complement(7418..7603)
                     /gene="cibA"
                     /locus_tag="VQU30_000677"
     CDS             complement(7418..7603)
                     /gene="cibA"
                     /locus_tag="VQU30_000677"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000180803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fratricide two-peptide bacteriocin subunit CibA"
                     /protein_id="HET2446828.1"
                     /translation="MTNFDILDNQFLSLSENELSDIDGGLAPLVIFGVAVSWKAIAGG
                     TALIGSGLAAGYFLGGD"
     gene            7781..8464
                     /gene="tsaB"
                     /locus_tag="VQU30_000678"
     CDS             7781..8464
                     /gene="tsaB"
                     /locus_tag="VQU30_000678"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000865689.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     dimerization subunit type 1 TsaB"
                     /protein_id="HET2446829.1"
                     /translation="MKVLAFDTSSKALSLAILEDKQVLAETTINIKKNHSITLMPAID
                     FLMESLDWTPKDLDRIVVAEGPGSYTGLRIAVATAKTLTHTLNIELVGMSSLLALVPY
                     QQEGLFVPLMDARRNNVYAGFYENAKPVMPEAHLSFEEVLEKVKGASQVTFVGEVGPF
                     VEQIQEHLPRTNYKETLPNAANLALLAWDKEADSLHDFVPNYLKRVEAEENWLKNHTE
                     SGESYIKRL"
     gene            8461..8898
                     /gene="rimI"
                     /locus_tag="VQU30_000679"
     CDS             8461..8898
                     /gene="rimI"
                     /locus_tag="VQU30_000679"
                     /EC_number="2.3.1.266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000569806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosomal protein S18-alanine
                     N-acetyltransferase"
                     /protein_id="HET2446830.1"
                     /translation="MIEIKRIQQQPDLAQAIYAVMAAVYLVSPWTLEQIQADLSQDQT
                     WYALAYDGAEVIGFLAVQENLFEAEVLQIAVKGAYQGQGIASALFAQLPTDKEIFLEV
                     RKSNQRAQAFYKKEKMAVIAERKAYYHDPVEDAIIMKREIDEG"
     gene            8888..9898
                     /gene="tsaD"
                     /locus_tag="VQU30_000680"
     CDS             8888..9898
                     /gene="tsaD"
                     /locus_tag="VQU30_000680"
                     /EC_number="2.3.1.234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002896630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     transferase subunit TsaD"
                     /protein_id="HET2446831.1"
                     /translation="MKDRYILAFETSCDETSVAVLKNDDELLSNVIASQIESHKRFGG
                     VVPEVASRHHVEVITACIEEALAEAGITEEDVTAVAVTYGPGLVGALLVGLSAAKAFA
                     WAHGLPLIPVNHMAGHLMAAQSVEPLEFPLLALLVSGGHTELVYVSEAGDYKIVGETR
                     DDAVGEAYDKVGRVMGLTYPAGREIDELAHQGQDIYDFPRAMIKEDNLEFSFSGLKSA
                     FINLYHNAEQKGESLSTEDLCASFQAAVMDILMAKTKKALEKYPVKTLVVAGGVAANK
                     GLRERLAAEITDVKVIIPPLRLCGDNAGMIAYASVSEWNKENFAGWDLNAKPSLAFDT
                     ME"
     gene            complement(9944..11244)
                     /locus_tag="VQU30_000681"
                     /pseudo
     CDS             complement(9944..11244)
                     /locus_tag="VQU30_000681"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677188.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
     gene            complement(11520..11871)
                     /locus_tag="VQU30_000682"
                     /pseudo
     CDS             complement(11520..11871)
                     /locus_tag="VQU30_000682"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(11978..12270)
                     /locus_tag="VQU30_000683"
                     /pseudo
     CDS             complement(11978..12270)
                     /locus_tag="VQU30_000683"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus and C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS630 family transposase"
     gene            12513..13719
                     /locus_tag="VQU30_000684"
                     /pseudo
     CDS             12513..13719
                     /locus_tag="VQU30_000684"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001200043.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 4 protein"
     gene            13712..14360
                     /locus_tag="VQU30_000685"
                     /pseudo
     CDS             13712..14360
                     /locus_tag="VQU30_000685"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397244.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
     gene            14370..15986
                     /locus_tag="VQU30_000686"
     CDS             14370..15986
                     /locus_tag="VQU30_000686"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000288036.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET2446832.1"
                     /translation="MYTIIKSNIKKFSLLTIFIVAGQLLLIYAATINALVLNELIAMN
                     LERFLKLSIYQMIVWCGIIFLDWVVKNYQVEVIQEFNLEIRNRVATDISNSTYQEFHS
                     KSSGTYLSWLNNDVQTLNDQAFKQLFLVIKGISGTIFAVVTLNHYHWSLTVATLFSLM
                     IMLLVPKIFASKMREVSLNLTNQNEAFLKSSETILNGFDVLASLNLLYVLPKKIKEAG
                     ILLKMVIQRKTTVETLAGAISFFLNIFFQISLVFLTGYLAIKGIVKIGTIEAIGALTG
                     VIFTALGELGGQLSSIIGTKPIFLKLYSINPIESNKMNDIEPNEVNRDFPLYEAKNIC
                     YKYGDKEILKNLNFCFQRNEKYLILGESGSGKSTLLKLLSGFLRDYSGELRFCGDDIK
                     KTSYLNMVSNVLYVDQKAYLFEGTIRDNILLEENYTDEEILQSLEQVGLSVKDFPNNI
                     LDYYVGDDGRLLSGGQKQKITLARGLIRNKKIVLIDEGTSAIDRRTSLAIERKILDRE
                     DLTVIIVTHAPHPELKQYFTKIYQFPKDFI"
     gene            16006..16850
                     /locus_tag="VQU30_000687"
                     /pseudo
     CDS             16006..16850
                     /locus_tag="VQU30_000687"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001813546.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            16918..18419
                     /locus_tag="VQU30_000688"
                     /pseudo
     CDS             16918..18419
                     /locus_tag="VQU30_000688"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001819023.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="asparagine synthase"
     gene            18431..19180
                     /locus_tag="VQU30_000689"
     CDS             18431..19180
                     /locus_tag="VQU30_000689"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000069862.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PIG-L family deacetylase"
                     /protein_id="HET2446833.1"
                     /translation="MSDNTKYIFLSPHLDDAIFSCGDYISKLTSEGEIVLVITIFSGY
                     PLSQQLQPSAKQFHKLCNLGKYPIEERKKEDRLACERLQCDFRHLSYYECLYRKDRNG
                     NFLYRHIYSKLKNEDTLKNDIIKELLMHLDDKCVVYCPLSLGDHVDHVFVNSIGRALE
                     FMRYKVIYYEDFPYVSDSSMVSYMGKTKELKMYQEELDEKHYIDRISSILCYKSQILI
                     IWKSVEKLLNNIKELYLRNGAAYSIRFWIKK"
     gene            19193..20365
                     /locus_tag="VQU30_000690"
     CDS             19193..20365
                     /locus_tag="VQU30_000690"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001017606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotide sugar dehydrogenase"
                     /protein_id="HET2446834.1"
                     /translation="MNIAVIGLGHVGLAYALLFASKYKVVAYDIDSVKINNLKKGTLP
                     SKNEELMKFFCENNLNITFFDTFSEIKNNIDYYIIALPTDYDEKIGSFNTYEIEQTVS
                     KILRVKPNGKIILKSTVPIGFSNKLKRLFDTKNIIFVPEFLREGCSIYDNLYPSRIVV
                     GDETVEGRKIAELFLSISTHSTANIKNVMLVSPTEAEAIKLFSNTFLALRVAFFNELD
                     SFAERRSLNAEVVIKGVCLDPRIGNFYNNPSFGFGGYCLPKDTRQLKKEFIEINAPVI
                     EAIDISNTNRKQFIVKQILERKPKIVGIYKLGMKYNSDNYKESAILSIINELLIVGIK
                     ILVYEPNLNVSIDNVIFEKNFELFIKQSDLIVANRWDRGLEAYKDKVYTRGIWIRD"
     gene            20760..21623
                     /locus_tag="VQU30_000691"
     CDS             20760..21623
                     /locus_tag="VQU30_000691"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000572848.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="XRE/MutR family transcriptional regulator"
                     /protein_id="HET2446835.1"
                     /translation="MIEKMELGEFYKELRLARKLKQSDVACAGLTASQLSKFELGQSM
                     LSADKLILAIQGINMNFDEFGHKLNNYQESPHMRIGRRVVDCFSHQDIAALEQLLEEV
                     DQEQMAQTYRRLNAIVIKNALHSLDKSYPLTEEDSEFLTTYLYAIESWTWFELYLFCN
                     TMPFLSNQDLIFLSTSLLEKSKEFKELVHNRWYMKSGYLNIISELMERKLFSYIPIFE
                     AELERMLRPYDVFEKVLWQFLKKMQIFLQTKGSNQKEIEHFIQSLQVLENPQLTALFE
                     LRLQQYKELID"
     gene            21909..22142
                     /locus_tag="VQU30_000692"
     CDS             21909..22142
                     /locus_tag="VQU30_000692"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000933479.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2446836.1"
                     /translation="MLNLQFAETMELTEAELQDVRGGNLVNSMGGGGRSGISGWGVPG
                     IYPGWGNQGMSPNRGAFDWTIDLADGLFGRRRR"
     gene            22164..22841
                     /locus_tag="VQU30_000693"
     CDS             22164..22841
                     /locus_tag="VQU30_000693"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000738309.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HET2446837.1"
                     /translation="MKKMKEVKFHLATGLLILTYYLIFNVTSDLDFMVALSDNMYYVF
                     QVLLVLILGTIATIAFVKSEHWKECGRFQFRWSYLGVFLLSFFLLFVWANLTTYIFPR
                     TQNGSTVVEVATSLTGISYFVTRILYTSIIAPVSEEVVCRGLLMTSLSKVKRYYLDVL
                     VSAAIFGAMHVLQYGWITTDFIKYFGMGLIFCMMFRYTRSIYWAIALHASWNSFLLIV
                     TLLVFGY"
     gene            22853..23518
                     /locus_tag="VQU30_000694"
     CDS             22853..23518
                     /locus_tag="VQU30_000694"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000720786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HET2446838.1"
                     /translation="MKKIISHRYFIIVFLLVIADQKFSVLVLRSDLVAGLSDFAYYLS
                     DMMLNFLVVLFALIAMIWSGKWQKINSRKFKGSYLFYSFLALLAFVAWNFVTFFLFPP
                     TRNEISYQHAAPTFTGATAFLMYFFYPVIAGPIFEDMIYRGLVMTALEKGKKWGLDVL
                     GSAILFGVSHISNHGWVLTDFFVYMGGGLIFAVLFRMTKSIYWPIGLHIVYNGIGQLL
                     MLL"
     gene            23590..24816
                     /locus_tag="VQU30_000695"
     CDS             23590..24816
                     /locus_tag="VQU30_000695"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000862399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HET2446839.1"
                     /translation="MKVFLQNRDFRQLTINQWISTLGDTIFYLAFLNYVADASFAPLA
                     ILLITISETLPQVLQIFLGVLADFQHHRVLKYTVISFTKFLLYSIVSLSLSGQSFSLL
                     LVTFICLLNLLSDTLSYFSGAMLTPIFIRIIGQDHLAEAIGFKQSTVSLVKTISNILG
                     GVLLGILSIQFISLLNALTFLIAFLGILFIKTDLLKVEKTISYQEGLSVKSFCQHLLQ
                     SSKLIWNMNKVLLVLFIISTSQAVINVTVPISTLFLRNQPFLNLQTGQSLALLATLEL
                     SALILGSLMSGYLQHTISIKIALYASLLLQLLLLVGFATAHFGLILIFSFLDAFFAGI
                     LSPRLQELVFKQIPEESMGAVQSSIGAITVVLPSLFTIALGTIATSFGTLAVSFVLLL
                     FLLVAFVMLLNIRESI"
     gene            complement(25167..25244)
                     /locus_tag="VQU30_000696"
                     /pseudo
     CDS             complement(25167..25244)
                     /locus_tag="VQU30_000696"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002674100.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopuranose mutase"
     gene            25315..25971
                     /locus_tag="VQU30_000697"
     CDS             25315..25971
                     /locus_tag="VQU30_000697"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001141648.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AzlC family ABC transporter permease"
                     /protein_id="HET2446840.1"
                     /translation="MPTALGYVSIGLACGTIGAPYVTPVEMGLMSLFVYAGSAQFAML
                     ALIVVQAPVAAIAMTVFLINLRLFLLSLHASTYFRHTSLWYNIGMSSILTDETYGVLM
                     GELAHTDKVNPMWMHGNNLNSYVAWFVGTVVGTALGGLLPNPEIFGLDFALVGMFIGI
                     FASQFQIMQRRIPVRNLLIILAVVAVSFFLLLTVVSQSLAVLFATLLGCSMGVVLDGQ
                     "
     gene            25961..26284
                     /locus_tag="VQU30_000698"
     CDS             25961..26284
                     /locus_tag="VQU30_000698"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000253911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AzlD domain-containing protein"
                     /protein_id="HET2446841.1"
                     /translation="MVSKYLLLAVIFSDLVTWILRMIPFILVKYKGLPAIVERFLKFL
                     PVSIIFALILSSVVTGKVGSLPQIKWLDFLAVFPTAWVAFRYRNLVGTVLFGVVLIAV
                     LRLVF"
     gene            26388..27218
                     /locus_tag="VQU30_000699"
     CDS             26388..27218
                     /locus_tag="VQU30_000699"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter substrate-binding
                     protein"
                     /protein_id="HET2446842.1"
                     /translation="MKKIVKYSSLAALGLVAAGVLAACSGGAKKEGQAASKKEIIVAT
                     NSSPKPFNYEENGELTGYEIEVVRAIFKDSDKYDVKFEKTEWSGVFAGLDADRYQMAV
                     NNISYTKERAEKYLYAAPTVKDPNVLVVKKDDSSIKSLDDVGGKSTEVVQGTTSAKQL
                     EDYNKQHSDNPTILNYTKANLQQIMGHLSDGQFDYKISDKITVETVIKNQGLDNLKVI
                     DLPSDQQPYVYPLLAKGQDELKTFVDKRIQELYKDGTLEKLSKQFFGDTYLPAEADIK
                     "
     gene            27259..27336
                     /locus_tag="VQU30_000700"
                     /pseudo
     CDS             27259..27336
                     /locus_tag="VQU30_000700"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000253911.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="AzlC protein"
     gene            27440..28270
                     /locus_tag="VQU30_000701"
     CDS             27440..28270
                     /locus_tag="VQU30_000701"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter substrate-binding
                     protein"
                     /protein_id="HET2446843.1"
                     /translation="MKKIVKYSSLAALALVAAGVLAACSGGAKKEGQAASKKEIIVAT
                     NGSPKPFIYEENGELTGYEIEVVRAIFKDSDKYNVKFEKTEWSGVFAGLDADRYNMAV
                     NNLSYTKERAEKYLYAAPIAQNPNVLVVKKDDSSIKSLDDIGGKSTEVVQATTSAKQL
                     EAYNAEHTDNPTILNYTKADFQQIMVRLSDGQFDYKIFDKIGVETVIKNQGLDNLKVI
                     ELPSDQQPYVYPLLAQGQDELKSFVDKRIKELYKDGTLEKLSKQFFGDTYLPAEADIK
                     "
     gene            28424..29278
                     /locus_tag="VQU30_000702"
     CDS             28424..29278
                     /locus_tag="VQU30_000702"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000694494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MetQ/NlpA family ABC transporter
                     substrate-binding protein"
                     /protein_id="HET2446844.1"
                     /translation="MKIKKWLGLAALATVAGLALAACGNSEKKADNATTIKIATVNRS
                     GSEEKRWDKIQELVKKDGITLEFTEFTDYSQPNKATADGEVDLNAFQHYNFLNNWNKE
                     NGKDLVAIADTYISPIRLYSGLNGSANKYTKVEDIPANGEIAVPNDATNESRALYLLQ
                     SAGLIKLDVSGTALATVANIKENPKNLKITELDASQTARSLSSVDAAVVNNTFVTEAK
                     LDYKKALFKEQADENSKQWYNIIVAKKDWETSPKADAIKKVIAAYHTDDVKKVIEESS
                     DGLDQPVW"
     gene            29378..30751
                     /locus_tag="VQU30_000703"
     CDS             29378..30751
                     /locus_tag="VQU30_000703"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M20/M25/M40 family metallo-hydrolase"
                     /protein_id="HET2446845.1"
                     /translation="MVFPSEQEQIEKFEKDHVVQHYFEVLRTLISKKSVFAQQVGLKE
                     VANYLGEIFKRVGAEVEIDESYTAPFVMAHFKSSRPDAKTLIFYNHYDTVPADGDQVW
                     TEDPFTLSVRNGFMYGRGVDDDKGHITARLSALRKYMQHHDDLPVNISFIMEGAEESA
                     STDLDKYLEKHADKLRGADLLVWEQGTKNALEQLEISGGNKGIVTFDAKVKSADVDIH
                     SSYGGVVESAPWYLLQALQSLRAADGRILVEGLYEEVQEPNEREMALLETYGQRNPEE
                     VSRIYGLELPLLQEERMAFLKRFFFEPALNIEGIQSGYQGQGVKTILPAEASAKLEVR
                     LVPGLEPHDVLEKIRKQLDKNGFDKVELYYTLGEMSYRSDMSAPAILNVIELAKKFYP
                     QGVSVLPTTAGTGPMHTVFDALEVPMVAFGLGNANSRDHGGDENVRIADYYTHIELVE
                     ELIRSYE"
     gene            30744..31805
                     /locus_tag="VQU30_000704"
     CDS             30744..31805
                     /locus_tag="VQU30_000704"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000032379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionine ABC transporter ATP-binding protein"
                     /protein_id="HET2446846.1"
                     /translation="MSRDIIKLDQIDVTFHQKKRTITAVKDVTIHIQEGDIYGIVGYS
                     GAGKSTLVRVINLLQKPSAGKITIDDDVIFDGKVTLTAEQLRRKRQDIGMIFQHFNLM
                     SQKTAEENVAFALKHSGLSKEEKKAKVAKLLDLVGLADRAENYPSQLSGGQKQRVAIA
                     RALANDPKILISDESTSALDPKTTKQILALLQDLNQKLGLTVVLITHEMQIVKDIANR
                     VAVMQDGHLIEEGSVLEIFSNPKQPLTQDFISTATGIDEAMVKIEKQEIVEHLSENSL
                     LVQLKYAGASTDEPLLNELYKHYQVMANILYGNIEILDGTPVGELVVVLSGEKAALAG
                     AQEAIRQAGVQLKVLKGGQ"
     gene            31807..32499
                     /locus_tag="VQU30_000705"
     CDS             31807..32499
                     /locus_tag="VQU30_000705"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255001.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HET2446847.1"
                     /translation="MESLIQTYLPNVYKMGWAGQAGWGTAIYLTLYMTVLSFIIGGFL
                     GLVAGLFLVLTAPGGVLENKVVFWILDKITSIFRAVPFIILLAILSPLSHLIVKTSIG
                     PNAALVPLSFAVFAFFARQVQVVLAELDGGVIEAAQASGATFWDIVGVYLSEGLPDLI
                     RVTTVTLISLVGETAMAGAVGAGGIGNVAIAYGFNRYNHDVTILATIIIILIIFAIQF
                     LGDFLTKKLSHK"
     gene            complement(32529..33098)
                     /locus_tag="VQU30_000706"
     CDS             complement(32529..33098)
                     /locus_tag="VQU30_000706"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000748387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MptD family putative ECF transporter S
                     component"
                     /protein_id="HET2446848.1"
                     /translation="MKKSILTTLLFAVLYFLCMGIGVLLGNLFDQTGNMFYAPAFTAL
                     VGGSVYMILVAKVPRFGAITTIGLVIALFFLGTKHGAGSFLPGIICGLLADGVAHLGK
                     YKDKTKNFLSFIIFAFSTTGPILLMWIAPKAYMATLLARGKSQEYIDRIMVAPNPGTV
                     LLFIASIVIGALVGALIGQALSKKFAQKI"
     gene            33233..33847
                     /locus_tag="VQU30_000707"
     CDS             33233..33847
                     /locus_tag="VQU30_000707"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000532354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YesL family protein"
                     /protein_id="HET2446849.1"
                     /translation="MGRFLDFVFNRFFLGMIATAFFWLLTLAGGIILGLAPASATLMS
                     LYAEHGYSFREYSLKEAWSLYKQNFVSSNLIFYSFLGVGLVLTYGLYLLVQLPHQTIV
                     HLIATLLNVLVVALIFLAYTVSLKLQVYFALSYRNSLKLSLIGIFMSLAAVAKVLLGT
                     VLLVAIGYYMPALLFFVGIGMWHFFISDMLEPVYEIIHEKLATK"
     gene            33849..35495
                     /locus_tag="VQU30_000708"
     CDS             33849..35495
                     /locus_tag="VQU30_000708"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013670288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HET2446850.1"
                     /translation="MKQFWLHTLLRTYSSVMIIIIASFAILLSYADWDSREKEAQRVA
                     QRVTARTVSEIEYYHRESTQIAQALVENQARIEGIYKYFSLSMPDYFYWQLERKASPY
                     ISVSLYENVDDLYVRNDFVTGVAIAFQDYKEVYVSTKDKRSGEKIRAEDFKPAGNSFA
                     IPVSDPVSDQDLGVIYISLDPAVLYHAIDNTRGHTPMAVTVTSPFDTEIFHIGETVDR
                     ESENWLVGLTSHGYQVQVAVPKNFVLQGTVTSSALIVGLSLLFIVILYLTLRQTFANY
                     QKQVVDLVESIQVIAQGEEGRRIDISEKDQELLLIAETTNDMLDRLEKNIHDIYQLEL
                     SQKDANMRALQAQINPHFMYNTLEFLRMYAVMQSQDELADIIYEFSSLLRNNISDERE
                     TLLKQELEFCRKYSYLCMVRYPKSIAYGFKIDPELENMKIPKFTLQPLVENYFAHGVD
                     HRRTDNVISIKALKQDGFVEILVVDNGRGMSAEKLANIREKLSQKYFEHRASYSDQRQ
                     SIGIVNVHERFVLYFGDRYAITIESAEQAGVQYRITIQDE"
     gene            35507..36793
                     /locus_tag="VQU30_000709"
     CDS             35507..36793
                     /locus_tag="VQU30_000709"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000278884.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HET2446851.1"
                     /translation="MYKVLLVDDEYMVTEGLKRLIPFDKWDMEVVATASHADEALEYV
                     QENPVDVIISDVNMPDKTGLDMIREMKEILPDAAYILLSGYQEFDYVKRAMNLSVVDY
                     LVKPVDKVELGNLLEKIAGQLGERGKKSQTLSQELDEAGFVSYLGDKENWWIGLSKEK
                     QGSFTIPYYVLGQDWQIFISDQPLDGLVVTPFEAPYQEHFERWKLNAEKTLFYGSVNL
                     QQSESLFAYYEPIYRVIIQGNLNQIVEELNLLEKVVLENTPRVPITKQLFIQFVMDVF
                     HLFEHLKADDLTDIVKTIHAIQSFDELVPYIKETLSSFFGQYRMNENVVSVLEVIGCD
                     YQKELSLKDISKALFINPVYLGQLIKRETDSTFAELLNKQRIKAAQQLLLSTSDSIED
                     ICYAVGYSNLGYFYKVFRKLCGKSPKAYRKQVETIL"
     gene            36854..37387
                     /locus_tag="VQU30_000710"
     CDS             36854..37387
                     /locus_tag="VQU30_000710"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399110.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HET2446852.1"
                     /translation="MKKKPIYLWVLLILSALISVPSLFGIVSPLPSKEALRTAQKQVA
                     GVNAQQLEDQLNYTYRVAEASHSIFNVALIVLSTILVVVAIVFLVRKNLQYANYTYVG
                     YVLLAIIGSIYGYVGLQDAVQLVQDESMRLTVSIGSKAVSIFYIVINVLFLALVFYKM
                     WRQQKASAEEEETEELA"
     gene            37465..37935
                     /gene="nrdI"
                     /locus_tag="VQU30_000711"
     CDS             37465..37935
                     /gene="nrdI"
                     /locus_tag="VQU30_000711"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000849618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class Ib ribonucleoside-diphosphate reductase
                     assembly flavoprotein NrdI"
                     /protein_id="HET2446853.1"
                     /translation="MKIISLVYISLSGNTESFVTRLKDYLLSQYKGIEVQKIHIKDLV
                     KEGKNFYEMDHPYVAFLPTYLEGGNGVDNGDVEILTTPVGDFIAYGNNASKCFGVVGS
                     GNRNFNNQYCLTAKQYSQRFGFPVLADFEMRGMLEDIKHVAAIIADLYELEKEN"
     gene            complement(38228..39490)
                     /locus_tag="VQU30_000712"
     CDS             complement(38228..39490)
                     /locus_tag="VQU30_000712"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000075801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="divalent metal cation transporter"
                     /protein_id="HET2446854.1"
                     /translation="MSQAISLNQSTWASKLKAMGPGILMATAAVGGSHIVSSTQAGGS
                     YGWSLLLLVILANVFKYPFFRFGAEYTADTGKTLVEGYAEKGKLYLWIFFILNVFSAM
                     VNTAGVAILCSAIIASAFPMIGLSITQWSLILVAIIWAMLLFGGYKLLDGMVKWIMSA
                     LTIATVLAVIIAAVKHPEYSSDFVEKTPWQMAALPFIVSLLGWMPAPIEISAINSLWS
                     AEKRKTVNFNTEDALFDFNTGYIGTAILAVFFVALGALIQYPTGQAVEAASAKYISQF
                     VGMYASVLGEWSRYLITFIAFLCIFGTVITVIDGYSRVNQESLRLLISQKEDNRKSLN
                     IWMTITAIIGIVIIKFFSGQVSTMLRFAMIGSFLTTPFFALLNYALVTRENKNLPSWL
                     KHLAIAGLIFLFGFAIFFIYALAIGKAG"
BASE COUNT        12026 a         6862 c         8542 g        12178 t
ORIGIN      
        1 ttaggtgccc ttgcagtcaa cacaactgta gatggctata aagtcaatgc caatggtgaa
       61 tgggtttaag ccgattaaat taaatcatgt taagaacatt tgacatttta attttgaaac
      121 aaagataagg ttcgattgaa tagatttatg ttcgtattct ttaggtacct atcttatgat
      181 ttcaggaaat gtcattaaaa aaacgactcc ttttctctaa cttgaaaaat agattagaga
      241 aaatgggttg ttttatttat tatagttatt tgaatgaaga taagaagaag gtatactcac
      301 atcattcaca taatctgtat gttgactata agtttaaaaa aacaattttt aagctcttcc
      361 ttgtcttctc caaccaagcg tgttataatg aatactgctc aagcgacctt caatcgtgaa
      421 gcacacacga ccttcaatcg tgaataaacg aatagatggg agacttacca tgagtgataa
      481 ctctaaaaca cgtgttgtcg tggggatgag tggtggtgtt gattcgtcgg tgacggctct
      541 tttgctcaag gagcagggct acgatgtgat cggtatcttc atgaagaact gggatgacac
      601 agatgaaaac ggcgtctgta cggcgaccga agattacaag gatgtggttg cggtggcaga
      661 ccagattggc attccctact actctgtcaa ttttgaaaaa gagtactggg accgcgtttt
      721 tgagtatttc ctagcggaat accgtgcagg gcgcacgcca aatccggacg ttatgtgcaa
      781 caaggaaatc aagttcaagg cctttttgga ctatgccatg accttggggg cagactatgt
      841 agcgactggg cattatgctc gagtggcgcg tgatgaggac ggcactgttc acatgcttcg
      901 tggcgtggac aatggcaagg accagaccta tttcctcagc caactttcgc aagaacaact
      961 ccaaaaaacc atgttccctc tgggacattt ggaaaagcct gaagtacgca gactagcaga
     1021 agaagcaggc ctttcgactg ctaagaagaa agactcgaca gggatttgct ttatcggaga
     1081 aaagaacttt aaaaactttc tcagcaacta cctgccagct cagcctggtc gcatgatgac
     1141 tgtggatggt cgcgatatgg gcgagcatgc aggtcttatg tactatacaa tcggtcagcg
     1201 tggcggactc ggtatcggtg ggcaacacgg cggtgacaat gccccttggt tcgttgtcgg
     1261 aaaagatcta agcaagaata ttctctatgt aggacaagga ttctaccatg attcgctcat
     1321 gtcaactagc ctagaagcca gtcaagtcca ctttactcgt gaaatgccag aagagtttac
     1381 gctagaatgt acggctaaat tccgttaccg tcagcctgac tctaaggtga ccgtccatgt
     1441 caaaggagac aaggcagaag ttatctttgc ggaaccacaa cgcgcgatta caccaggaca
     1501 ggcagttgtc ttttacgatg gcgaagagtg tctaggtggc ggtttgattg acaatgctta
     1561 ccgcgatgga caagtttgtc agtacattta gattgacaaa ttttctcaat ttgctacaat
     1621 aataacagca atagaaatga tggtcaaagc tcatggatgt tgcaggcttt tttgtcctgc
     1681 acttctttgt agttttgact gtttttgtgt cgtttaaggg aaaggacaag aatgactcaa
     1741 caagactttc ggacaaaagt agacaatacg gtttttggtg ttcgggctac agccttgatt
     1801 gtccaaaatc acaagcttct agttaccaaa gacaagggca agtattacac tattggaggt
     1861 gcgattcaag tcaatgaaag cacggaagac gcggtagtcc gtgaagtgaa ggaagaactg
     1921 gatgtcaaag ctcaagctgg gcagctagct tttgtggttg aaaatcgttt tgaagtggac
     1981 ggcgtttcct atcacaatat cgagtttcat tatctggtgg atttgcttga agatgccccg
     2041 ttgaccatgc aggaagatga gaaaaggcag ccctgtgagt ggattgactt ggataagctc
     2101 cagaatatcc agctagttcc agccttttta aaaacagccc taccagattg ggaaggccaa
     2161 ctaagacaca ttcatcttga ggaataggag agaaacatga cttatcattt tactgaagaa
     2221 tacgatatta ttgtaattgg tgcgggacac gctggggttg aggcttcctt ggccgctagc
     2281 cgtatgggct gtaaggtcct gcttgcgacc atcaatattg aaatgctggc tttcatgcct
     2341 tgtaatccct ctatcggtgg ttctgctaag gggattgtcg tacgtgaagt cgatgccctc
     2401 ggtggcgaga tggccaagac cattgacaag acttacatcc agatgaagat gctcaacaca
     2461 gggaagggac cagccgttcg tgcccttcgt gcgcaggctg ataaggaact ttactctaag
     2521 gaaatgcgca agacagttga aaatcaagaa aatctgaccc ttcgtcaaac catgattgat
     2581 gagattttgg tggaagatgg caaggttgtc ggtgtgcgta cagccaccca tcaagaatat
     2641 gctgctaagg ctgttattgt gacgacaggg actgctctcc gtggggaaat tatcatcgga
     2701 gacctcaagt actcatcagg tcctaaccac agcttggctt ctattaacct agctgacaat
     2761 ctcaaggaac tgggtctcga aatcggtcgt ttcaagacag gaacccctcc acgtgtcaag
     2821 gcttcttcta tcaattacga tgtgacggaa attcagccag gagacgaagt gcctaatcat
     2881 ttctcataca cttcacgtga tgaggattat gtcaaagatc aagtgccatg ctggttgacc
     2941 tataccaatg gtaccagtca tgagattatc caaaacaacc tccaccgtgc gcctatgttt
     3001 acaggtgtgg tcaagggagt ggggcctcgt tactgtccgt cgattgaaga caagattgtg
     3061 cgctttgcgg acaaggaacg tcaccaactc ttccttgagc cagaagggcg caatactgag
     3121 gaagtctatg ttcaaggact ttcaaccagt ctgcctgagg atgtccagcg tgacttggtt
     3181 cattccatca aaggtttgga aaatgcagag atgatgcgga caggttatgc tattgagtat
     3241 gatatggtct tgcctcatca gttgcgtgcg actttggaaa ccaagaaaat ctcaggtctc
     3301 ttcactgctg gtcagacaaa tggaacatca ggttatgaag aagctgctgg ccaagggatt
     3361 atcgcgggta tcaatgcggc tctgaaaatc caaggtaaac ctgagttgat tctaaaacga
     3421 agtgacggtt atatcggggt gatgatcgac gacttggtga ccaagggaac cattgaacct
     3481 taccgtctct tgaccagtcg tgctgaatac cgtctcattc ttcgtcatga caatgctgat
     3541 atgcgcttga ctgagatggg acgcgagatt ggccttgtgg atgatgaacg ctgggctcgt
     3601 tttgaaatca agaaaaatca atttgataat gagatgaaac gcctagacag tatcaaactc
     3661 aagccagtca aggaaaccaa tgctaaggtt gaggaaatgg gcttcaagcc gttgacagat
     3721 gcggtgacag ccaaggaatt ccttcgccgt ccagaagttt cttaccaaga tgtggtggcc
     3781 ttcatcggac cagctgcaga agacttggat gacaagatta tcgaattgat tgaaacagaa
     3841 atcaagtacg aaggctatat ttccaaagcc atggatcagg ttgctaagat gaaacgtatg
     3901 gaagaaaaac gcattccagc caatatcgac tgggatgaca tcgattctat tgcgacggaa
     3961 gctcgtcaga agttcaaact catcaatcca gaaaccatcg gccaagccag ccgtatttcg
     4021 ggagtaaacc cagcagatat ttctattttg atggtgtatc tggaaggtaa aaatcgtagt
     4081 atttctaaaa ctcttcaaaa atcaaaatga tacgtcgtcg gcttcttacg aatgagttca
     4141 aagcttggct ttgattcatc tccaacctcc catagttccc cgaactatgg gagctaactc
     4201 aagttatgca ttttcctagc cttctggtct gattttcatt gagttttaat ctcaaaagaa
     4261 agcatagaga aaaacagctc cgaagacggg gctgttttgt tgacttgtac tcaatgaaaa
     4321 tcaaagagca aactaggaag ctagccgtag gttgctcaaa gcactgcttt gaggttgtag
     4381 atagaactga cgaagtcagc tcaaaacaca gttttgaggt tgtagataga actgacgaag
     4441 tcagctcaaa acacagtttt gaggttgtgg atagaactga cgaagtcagt aacatatata
     4501 cggcaaggcg aagctgacgt ggtttgaaga gtattattct tcatctggtg tgaggatcat
     4561 cgggatgatg atcggttcac gttcggtatt ttcatagagg aaggggcgaa tagcgttgac
     4621 aatggcacca ttgacagatt gcacgctagc atccttattt ttcagtgcga tacgaatggc
     4681 attgaagagg atacgctggc tttggcgaat caagtctcca gactctctca tgtagacaaa
     4741 gcctcggctg aggatatctg ggccagacag aatcatctgc gatttgaagt caacagttgc
     4801 gactgccaga acgacaccgt cttcagatag atcgcgacga tctttgagga cagctgcgcc
     4861 aatttcaccg atacgatttc catcgacata gatatcttgg gcgttgaaat gacctgcgat
     4921 acgagctgag tcagcagtaa gggcaagcac atcgccattg ctcatgataa agatattgtc
     4981 tttctcaaca ccagtatcca ctgctagtcc agcgtggact ttttgcatgc ggtattcacc
     5041 gtggacaggc atgaagtatt ttggcttaat caagcggagc atgagttttt gctcttgctg
     5101 accaccgtgt ccagatgtat ggatattgtt cactttaccg tggataactt cgacaccagc
     5161 ttcagaaatg atgttaatca gcttgttgac gctagtagtg tttccaggga tgggactaga
     5221 agagaagata acggtatcac ctggttgtaa ttgtacttga cggtgggttc cgttggcgat
     5281 acgagagagg gctgccatag gctcaccctg actacctgta cagaggataa gaacttctcc
     5341 tgcaggataa tctttgattt catttggctc gataaaggtt cccttaggag ctttgatgta
     5401 gccaagatcg attccgttga caatggcctt ttccatagaa cgaccaaaga ccgcaatctt
     5461 gcgtccagtc ttaacagcag cttctgttgc ctgctggaga cggaagatat ttgaggcaaa
     5521 ggatgcaaag atgatacgtc cttcaatacc ttggataatc ttcataatgg actgaccaac
     5581 gactttttca gagttggtaa aggttggtac ttccgcattt gtcgagtcag acaggagaca
     5641 gagcacgcct tcttcaccaa gcgcagccat acgatgcaag tccgcaggtt ctccaactgg
     5701 agtaaagtcg aacttaaagt cacccgtaca gacgattttc ccttgaggag tatgaatgac
     5761 aatccccaaa ggctctggaa tagagtgagt cgttctaaag aaagttgcct tgagattttt
     5821 aaaggtcaac tcggtgttgt ggttgatttc gtaaagtttg gcgttgcgca agaggccgtg
     5881 ttcttcgagt ttcccacgga tcaaagccaa ggcaagcggt ccagcgtaga tagggacatt
     5941 tgcttgcttg agtaggaacg gaatcccacc aatgtggtcc tcgtgtccgt gtgtgattaa
     6001 aacagccttg acgcggtcga tattgtctac gatgtaagag tagtcaggaa tgacatagtc
     6061 gataccaagc aagtcatctt ctgggaattt aatcccagca tcgacgatga taatctcgtc
     6121 ttggtattca attccgtaag tgtttttccc gatttctcct agaccaccga tggcaaaaac
     6181 accgacttct tcaggtttaa gagtgtaggc catattagaa ctccgtaatt tcgaaggcgc
     6241 cagtttcttt ttcgtaatcg agcaatttgt cagacaagag ttcgatatat tcgatattgt
     6301 actctgggcg attttcttcg acaagttggc gagcagtgat acggccctca agttctgagc
     6361 tggcatcgat gtctaggtaa agcgcgcgtg ttgtttcacg gcgtgggcta cgttcttttg
     6421 tttcttgata aaaaactttg taaatcatat agttcctttc tatttacagg tcagcttatt
     6481 ccaaactttt agcagatatt tgcttgattt cattccattt tgtgtctaga ttgaccttga
     6541 ttcgttacaa ttatttcaat tataccacaa aatgaaaaat tagtaaaaga cggaaacgag
     6601 aaagttaggg gacgatttct tcggtaagcg tttgcaaaaa caaagaaaat gtgttatgtt
     6661 gataacggaa gtgaagttta ttacttgtca taattccata tagattttaa gtcaaggagg
     6721 ttgccctatg tataacttat ttgcttttgc tatcggagtt cgtttgctag cttttatcgt
     6781 ttttgttttg cgtttatgga ggaaatcttc tatttgccaa actggaacga tgacaaacca
     6841 agttcttgag gaaaattacc tttgtgactc tctactcgct ttttctcctc ctcgtgacct
     6901 atgtcgtttg gtttgtattt tactttggat taaatgctta gatgccctgc ttatgctggg
     6961 gttttttgtt tggggatgta gagatagtag atttacgaca cgaaaattcc accccatcta
     7021 tcaagatgag gtggtctttg catttttcta aaatgatatg acaatggaat tttcaaagct
     7081 tattattttt atgggagtca ttgttctgct caaaaataga gttgaagcat aaaaataaaa
     7141 caatacaaac agataaatcg aatggtaaag ggatggtagt aatgttcaaa tcattgagaa
     7201 tgctgagcaa actgtaagag atgaagacaa taaaatttat ccttctaaaa atgtgtttct
     7261 tatctagcat gacttaccaa actttttacg aaggtctttt ccaatggtat aacctgccat
     7321 aaataaagcg ataccaacac ctacaccaaa gccacccttg atttcttgca attccttatt
     7381 agaaatttca cgacagttgt tcaaatcttt catcatatta atctcctcct aaaaaataac
     7441 cagctgccaa accagaacct ataagtgctg ttccacctgc aatagctttc caagatactg
     7501 ctactccaaa gataaccaag ggagcgagac cgccatcaat atctgataat tcattttcag
     7561 ataaggataa aaattgattg tcaagaatgt caaaatttgt cattgaactt tcctcctttt
     7621 ttcttgttca cttttatatt cggaaaagaa aaggaaaagt gagcattttt ttaaattatt
     7681 tttagttaag tgagggcact cttgtctggg ggcaaagaaa attcccatgt gccatctttt
     7741 gtagtataat agtaagcaga caaaaagata ggaatgtgtt atgaaagtat tagcttttga
     7801 tacgtccagc aaggctcttt ctctcgctat tttagaggat aagcaggttc ttgccgagac
     7861 gacgattaat atcaagaaaa atcacagtat taccctcatg ccagccattg attttttgat
     7921 ggagagtttg gactggacgc ccaaggattt ggaccgaatc gtggtggcgg aagggccagg
     7981 tagctacaca ggcttgcgaa tcgcggtagc cactgccaag accttgactc atactctgaa
     8041 cattgagtta gttggtatgt ctagcctctt ggctctggtg ccatatcaac aagaaggctt
     8101 gttcgttcct ttgatggatg cgcgtcgcaa caatgtttat gcaggatttt atgaaaatgc
     8161 taaacctgtc atgccagaag cgcacctatc ttttgaagag gtgctagaaa aagtcaaggg
     8221 tgctagtcag gtaacctttg tcggagaagt tggccccttt gtggagcaga ttcaagaaca
     8281 cttgccaagg actaattata aagaaacctt gcctaatgca gccaatcttg ctcttttagc
     8341 ttgggacaag gaagcagact ccttgcatga ttttgtgcca aattacctca aacgagtcga
     8401 ggctgaggaa aactggctca agaaccatac cgagtctggt gagtcctaca ttaaacgcct
     8461 atgatagaaa tcaagcgaat tcaacaacag cctgacctag ctcaagccat ctacgctgtt
     8521 atggcagctg tttacctagt cagtccttgg actctggagc aaatccaagc agatctgtcc
     8581 caagaccaga cttggtatgc attggcttat gatggggcag aagtgattgg atttctagct
     8641 gtgcaggaga atctttttga agcagaagtc ctgcaaatcg ctgtcaaagg agcttatcag
     8701 ggtcagggaa ttgcgtcagc cttgtttgct caattgccga cagataagga gattttcctc
     8761 gaagtcagaa agtcaaatca acgagcgcaa gcattttaca agaaagaaaa aatggcggtc
     8821 atcgctgagc gaaaggccta ctaccatgac ccagtcgagg acgccattat catgaagaga
     8881 gaaatagatg aaggatagat atattttagc atttgagaca tcctgtgatg agaccagtgt
     8941 cgccgtcttg aaaaacgacg atgagctctt gtccaatgtc attgctagtc aaattgagag
     9001 tcacaaacgt tttggtggcg tagtgcccga agtagccagt cgtcaccatg tcgaggtcat
     9061 tacagcctgt atcgaggagg cattggcaga agcagggatt accgaagagg acgtgacagc
     9121 tgttgcggtt acctacggac caggcttggt cggagccttg ctagttggtt tgtcagctgc
     9181 caaggccttt gcttgggctc acggacttcc actgattcct gttaatcaca tggctgggca
     9241 cctcatggca gctcagagtg tggagccttt ggagtttccc ttgctagccc tcttggtcag
     9301 cggcggacac acagagttgg tttatgtttc ggaggcagga gattataaga ttgttgggga
     9361 aacccgtgat gatgcggttg gtgaggctta tgataaggtc ggccgtgtca tgggcttgac
     9421 ctatcctgca ggtcgtgaga ttgacgagct ggctcatcag gggcaggata tttatgattt
     9481 cccccgtgcc atgattaagg aagataatct ggagttctcc ttctcaggtt tgaaatctgc
     9541 ctttatcaat ctttatcaca atgccgagca aaagggagaa agcctgtcta cagaagattt
     9601 gtgtgcttcc ttccaagcag cagttatgga cattctcatg gcaaaaacca agaaggcttt
     9661 ggagaaatat cctgttaaaa ccctggttgt ggcaggtggt gtggcagcca ataaaggtct
     9721 cagagaacgc ctagcagccg aaatcacaga tgtcaaggtt atcatccccc ctctgcgact
     9781 ctgcggagac aatgcaggta tgattgccta tgccagcgtc agcgagtgga acaaagaaaa
     9841 cttcgcaggc tgggacctca atgccaaacc aagtcttgcc tttgatacca tggaataaag
     9901 agtggctctt tgtcaagtgt agtgggtagt cgaaaagctg caatctggag agtacgaaat
     9961 tcgtactctc ttttttgatg ttcaaagtca tcaaaatccg ttttttaaaa ttgttaaagt
    10021 tccggaaacc aaaggctttg cgcttgataa tcttaatcaa attattggtc gcttcaagtt
    10081 tagcgttgga ataaggcagc ttaagtgcgt tgataatctt atctctatcc cttaaaaaag
    10141 tccaaaagac cgtttgaaaa agcggatgaa ccgttggcag ttcttgctca atcaatccaa
    10201 agaaatggtc ggcattcttc tcttgaaaat gaaagagcag gagttgatag agttcgtagt
    10261 gaacctgtaa tccctcagag taagaaagca gcttatctcg tacttcccga tgggttaagt
    10321 gcattcgaaa cgtgggctga tagaatcgtt tctgacagag cttgaagcta tactggtgta
    10381 gtaaatcagt ccagtggact gatttagccc gagcctagaa acgaaaaagc gagggttcca
    10441 aaagcgcttg agcgcccgat actccaagga ttttcggtca aattggttca tgatttggat
    10501 tcgtactcgg ttcatagctc ggctcagatg ttggacaatg tggaagcggt caagaacaat
    10561 cttcgccttt ggaaagagtt gcttagcgag ccgataataa gggctgtaca tgtccatggt
    10621 gatgacctcg accagctccc gaacctctct ctgatagcgt tggaaatggt ttcgaatcac
    10681 cgcatgagtt cgcccgtcta aaattgcgag gatggatttg gactcaaaat cttgggcaat
    10741 gaagctcatt ttgctctttt tgaagctata ctcatcccaa ctcataactt ttggcaactt
    10801 ggtccaatcg gtttcaaact taaattccct cagttttcgg atgacggtgg aagttgagac
    10861 cgccaatctg tgggcaatct cagtcataga ctgcttttca aggaggagct gagcgatttt
    10921 ttgtctcacc atgttggaaa tctggcaatt tttcttgaca atggatgttt gagaaacgac
    10981 caccttaagg caattcttgc actgaaagcg gcgctttttg agatgcagta ccgtgggtaa
    11041 accctgacag tcgagaagcg gaattttaga ggctttctgg aagtcgtatt tgatcatctt
    11101 cccttgacaa tgaggacaag gaggagcggg ggaatccaac tttgcctgaa cgactagatg
    11161 ggtttggtat ttcagaacag acaagatttt gatatttttg tcttccaatc cgagcaaatc
    11221 tgtggtattc ttaagttgtt ccatatggac cctttctaat gagttggtta gacgcttttc
    11281 attataggtc atatggggct ttttttctac aagaaacgac cctataattc ctggggtggg
    11341 attacccact acagaaatta tagagccaaa gcattccaaa gtcttgtctg actctggaat
    11401 gttttctgtt cacagttgtt ttgtaactgc ctaataagta accgcgctat aacgaggtat
    11461 ctaccgagat tgtcaattct ccagtatact gttataaaaa acaaaactgg aggatttttt
    11521 tatgtcctcc catcgtccca tcgactgttc cgtagctgcc caataacgga gtatagtcgg
    11581 ctgaaacaag aataggacaa aagtgcctca agaaaagcat cgtaatttga caatattatt
    11641 ctgagatgtt tttgatgtaa gcccatattt tctcaatggg attatactcg ggtgaatagg
    11701 taggaagtgg taacagtcta tgccctgctc cttacacatg ttcattctgt gaaaccttgc
    11761 attgtccata atgataaggg atggtgtatc taaagtaggt agtaagaatt tttggaagca
    11821 agcttcgaaa aagtcactcg tcatcgtatc tttataggtc atcggagcca tagtatattg
    11881 aaacaaaaaa gggcattagt acttctataa cagtatcgca atctctggtg tgcgttgtct
    11941 cgatcttaat tcaaataatt atatcttctt ccagagagac taactgcctg ctcaaggctc
    12001 gatcatattt gagataaaaa taggtctcaa cccctgtctc ataaatataa ataggagtca
    12061 ggtagcttaa gtgattcaat tctttaagga accgatttac tttttctggg tcttgttcgc
    12121 agtaggtacg gctcttttta gactatatcc catagccttt agagcgtaat gaatagttgt
    12181 tggaggacag ttgaattcag cagctatttc agtcaaataa gcatcgggat gagtttcaat
    12241 atagatcttt aatttatctc tatcaacttt ttcaattaat agtggaagtt ttcttaaagt
    12301 tagtgtgttg aaacgttttt atacagtgct aaaatttgaa gtgtagtgca gatgtatttg
    12361 taatagtatt atagcaattc tttggagaag gtcgagacaa gagaaaatag gtatctttga
    12421 gatataagta tgatttacta taaaattatt gagttattca taaaaatttc tctatcaaat
    12481 atcataatgc gtcgtttaag gagatggtta caatgcaata tagttgtgga aaaataaata
    12541 ttaatatccc tgatggatat ggagacatta aggatatagt gttttcggct catattatag
    12601 ttaggtataa taatggacat tgtggaggta tagatccgca tataattgga ctttgtaaaa
    12661 agcagatcag aaggatgtct ccatatccta ttttgataat cgtatctaga gattcaaagg
    12721 ttattgatga ttataaaaat ttagatattg cctatgttga ttgtactcaa tgttcaaata
    12781 attttgaaac tgccttacac gttaaaaata ttttaaaatt attaaaaatc caacttatac
    12841 actgtcatgg ctactcaact aattattttt tatatatgtt aaaaaaactt gacaagaatg
    12901 gatttggaaa ggttaagaca gtgataacat gccatggatg ggttgaatat aacttaaaaa
    12961 agaaattctt gacttatttt gatttttgga catattctat gggagatgct tttatttgtg
    13021 tatctgaaac tatgaaaaaa agattggaga gtataataaa aaaataagaa gatagttgca
    13081 ataaataacg gaattaatgt atcaaatagc gatttagatg tagtaggtgt tcaagacttt
    13141 aaaaaagaat tttgtattcc aaataacaaa aaaatcattt gttatgttgg aaggttggat
    13201 ccagaaaaaa ggccggatag attccttgaa tttgcagaaa aattattttt agtcagagaa
    13261 gatgtgattt ttattatggc tggaaatggt agtatgtggg ctactttgaa agaaaaaatt
    13321 tgccatttga aatgtagaga taatttcagg ttacttggtg aaatctatcc agctactata
    13381 gtttaccaaa tatcggattt attgtatatt ccttctgata cagaaggaat acctatgtgt
    13441 gttttagagt caatgtcaca agaaactccg gttttagcta gtaatgttgg cgggttaagt
    13501 gaaattattg aacatagggt tgatggattt ttatttgaga aggaagatgt tgagggagtg
    13561 tgtgcttgtg ctaatttttt actcaatgat tctgagtatt tgaaatatat aggtgagaat
    13621 agtaaatcaa aaataagaaa acatttttct gtgcaaaaaa tgtttgtaga aaccatgaga
    13681 gtatatgatg aattattaga gaagagtagt catggatagg aatatagatc aagaattagt
    13741 aagtattata ataccaacac ataataggta tgaatctctg attagagctg tgaaaagttg
    13801 tttacatcaa agttataaaa atatcgaagt tataattatt gatgataatt atagtaatgt
    13861 aaatttaaga aataaaatta tccatcaatt tggctatacc agtcatagaa ttaagttaat
    13921 tttaagtaat gaagatttag gtgcaactaa tgccagaaac ataggtatca aaaattctag
    13981 aggtaagtat atatcatttt tagacgatga tgatgaatat atgccagatc gaattttaaa
    14041 gttgatggct tgttttaaaa agagtagaat gaagaattta gctttagttt atagttatgg
    14101 aataataatt tatccaatag gaaatatttt aatttattga gtttcaacga gagaatattg
    14161 gttacaaaga aatattattc tttaaacata aagcggttac tattaatagg agacaaatgc
    14221 aaggctttaa aagtaatcaa gaaggcaaga gaagaaaaaa tttttaacga atttcttttt
    14281 cgaaatatat gttattatat cattttggtt ttttctattg tatatatgac aactatgttc
    14341 aattaaaatt tagaaagtga gaaactattg tgtatactat tataaaatca aatataaaaa
    14401 aatttagttt attaacgata tttattgttg ctggtcaatt attgctaatt tatgcagcaa
    14461 ctattaatgc tctggtgttg aatgaattaa ttgcgatgaa tttagagcgg tttttgaaat
    14521 tgtcaatcta ccaaatgatt gtctggtgtg ggataatatt ccttgactgg gtagtgaaaa
    14581 attatcaggt tgaagtgatc caagagttta atctagagat tcgaaataga gttgccacag
    14641 acatctctaa ctctacctat caagaatttc atagtaaatc atcaggaaca tatctttcgt
    14701 ggctaaataa tgatgttcag actttaaatg atcaggcttt taaacaactt tttttagtaa
    14761 taaaaggaat ttctggtact atatttgcag ttgtgactct taatcactat cattggtcat
    14821 tgactgtagc caccttgttt tcattaatga ttatgctact tgtaccaaaa atctttgcat
    14881 cgaaaatgcg agaagttagt ctaaatttaa ctaaccaaaa tgaagctttt ttaaaatcta
    14941 gtgagactat attgaatgga tttgatgtgt tagcgtcctt gaatctttta tatgtattgc
    15001 ctaagaaaat taaagaagca ggaattttat taaagatggt tatacaaaga aagacaactg
    15061 tagaaacgtt agcaggcgct attagcttct ttctcaatat tttttttcag atatctctcg
    15121 tttttttaac aggctatctt gcaataaaag gaatagtgaa aattggtact attgaagcaa
    15181 taggagcact aacaggtgtt atttttacag cgctaggtga attaggaggt caattatcct
    15241 ctattattgg tacgaagcct atttttttaa aattgtattc aattaatcca attgagtcaa
    15301 ataaaatgaa tgatatcgaa ccaaatgagg tgaatagaga ttttccgtta tatgaagcaa
    15361 aaaatatttg ctataagtat ggagataaag aaatattaaa aaacttaaat ttttgttttc
    15421 aacgtaatga aaagtattta attttaggtg aaagtggaag cgggaaatct acattattaa
    15481 aattattgag tggctttttg agagattata gtggagaatt gcgattctgc ggggatgata
    15541 taaaaaaaac ctcctattta aatatggttt cgaatgttct atatgtagat caaaaagctt
    15601 atttgtttga aggtacgatt agagataata ttttattgga agaaaattat actgatgaag
    15661 aaatactaca gtctttagag caagttggtt tgagtgtaaa agattttcct aataacattt
    15721 tagattatta tgttggtgat gatgggagat tactgtcagg agggcagaaa caaaaaatta
    15781 ctttagctag agggctaatt agaaataaga aaatagtatt aattgacgag ggaacttctg
    15841 ctatcgatag gagaacttcg ttagcgattg aacgtaagat attagataga gaggatttga
    15901 ctgtcattat tgttacccat gctccgcatc cggaacttaa acaatatttt actaagatat
    15961 atcaatttcc aaaggatttt atttaagaat ataggggagg gaaacatgag attctattgt
    16021 gaagcttatg aggtaattac tgaagagaaa aaagtatact ttaatgatat tgagttagaa
    16081 gttaagtatt cctctgtcga agaattgttt ataatatgtg agaaattatt agataagaaa
    16141 aaagtatcat ttttttatgt atatgagaaa cccttaaggt atctgttatt tgactatata
    16201 tttctactag ttctagctaa aaaaaatatc ccaatcttag atggagtttc caataagcaa
    16261 gttgatccaa cgttgctgca tcacttttct ttggaaattg aaaagaattt tatcgatttt
    16321 tgctataaaa atatggatct catcctaaaa actcaaagta tatctttgtg tcatagagaa
    16381 gagcttatta ttgtagatgt ttcagatgac tctaaatttg gtgtttttta caagcgtttt
    16441 agaacactgg ttgataaaaa taacggaaaa tatgtttgtg tttataattt cagtcgtgtt
    16501 tcagatatac tgcaaaactg gaaaaattat tgcaatcgaa aattttcggt tacgtttact
    16561 gaaagccaat ttgaattatt taagctttta tataatcaaa aaaattttaa aacaatttcg
    16621 ttgctatttg gaaaaaaatt gttgctggag gaattatcta ttatagcgat cttactaata
    16681 tagaatactt ttgtattttt tggtgggata gtatgtttgg gaaagattct attggaaaat
    16741 acgtatatgt agaagagatt agtagatgtc attttttaga tagaaattat tctttttgtt
    16801 atggtttaca agattataaa agtaaactta ttaaatattt tttagaatag ttaatctatt
    16861 cgagagagat aaagaaatat ggaaaatact ttattgaata tcacaggaag cttcgatatg
    16921 gaaactagga atctaattag ttattcttta actgatatct ttgaaacaga taaaataaga
    16981 attgaacttc ttggagaaat ttattataaa aatataaagt tggaattgca tgaattcgct
    17041 ggattgtata agatttatgg aattagctta ataaagaata ttaccggaat gtttttaatt
    17101 ataatttttg atacgaagac aaaagaatta aaaatttttc aagatataac gacttcatac
    17161 tttaatttat actatactgt ttatggaggt gtgttctata tatagtacat ctttaaagaa
    17221 agtgatgaag ttatctcatg ttcccgttac cttaaataac aaaaaaatac aagaatttat
    17281 gagaaatgga tttattttag attcaaatac tttagtaacc gaaattaata aattagaata
    17341 tttctcttac atttctgtaa ataatactct tcgtatatgt ggtattgatt ataatgattc
    17401 aaacaatttt actaaagaac aagtattaaa gaattgggac tctatgctac gtgaatctat
    17461 attaagagtg tatagtgaag caggagaggc taatattaca ctatcatctg gttttgattc
    17521 aaattatata ttatatacat tagcgaatta tacgaattct tcaattaatg cattttgcat
    17581 aggaggagaa aaaggaatta atgagattcc tgaagtaact aaaattgcaa aattttatgg
    17641 tataaattta ttagttgata ctgtaatgag cccaagattt agaatatttt cccgatatag
    17701 tatggagatt ggaaggaagt ctctttgaat gtggtgtcat actgcagtac tatttaggca
    17761 ggttgttgtt ccaaaaaggg aacacaagta ttctttgtgg cgagtcagcg gatgaaataa
    17821 tgacttttaa gtatcattct gtgaactaca atcaattttg taatgataaa cagaagtcag
    17881 tatattttag ttattccgac tatccatttt atgttacaaa ttcaattgtt ttaaagaaaa
    17941 atagcctact tttgcatagt tttggcattc atcctagata tccatataaa atgtctgaga
    18001 ttgttgaaat gtctaaaaaa atatcagatc taaacgataa aaaagaattt cacaaaaaga
    18061 actgtgagtt gaggtttcaa gatagtgttc ttgataacat aaatagtgtc ccgggtacaa
    18121 ctcatttatt tagttgttta aatattcaaa cattagtaaa aattatttta tatatttttc
    18181 gatacaacag ttgtatgaaa atatttaatt ttagagataa agagcttatc ttttttaata
    18241 agattgtaaa tgggctgata caaaatattg aggagaattt agaggatgat attgaaagga
    18301 tattgaaata tttatatata tgtttattta acgaaatatt cattattaag aataaggtga
    18361 atttttttga tgatgtggaa tttaatcaga cacttagtga gtttttagat aaattgtaga
    18421 gggaatggtt atgagtgaca atactaagta tatcttttta tctccacatt tagatgacgc
    18481 aattttttcc tgtggtgatt atatttcaaa attaacttca gaaggagaaa ttgtacttgt
    18541 tattactata ttttctggtt accctttgag ccaacagcta cagccctctg ctaagcaatt
    18601 tcataagttg tgtaaccttg ggaaatatcc gattgaagaa aggaagaaag aagacaggtt
    18661 agcttgtgaa cgtctacaat gtgattttag acacttatcg tactatgaat gtctctatag
    18721 gaaagataga aatggcaatt ttctataccg tcatatctat agtaaattaa aaaatgagga
    18781 cacattaaag aatgatatca taaaagagct gttaatgcat ttagacgaca aatgtgtcgt
    18841 atattgtccg ctttcacttg gtgaccatgt tgatcatgtt tttgtgaata gtattggaag
    18901 ggcgcttgaa tttatgcgtt ataaagtaat atattatgag gacttcccat atgtaagtga
    18961 tagtagtatg gttagttata tgggaaaaac taaagaatta aaaatgtatc aagaggaact
    19021 tgatgaaaaa cattatattg atagaatatc atcaatattg tgctataaat ctcagatttt
    19081 gataatctgg aaatcagttg aaaaactttt aaacaatatt aaagagttgt atttaaggaa
    19141 tggggcagct tattctatta gattttggat taagaaataa ggaagtagtt ttatgaatat
    19201 agcagtaatt ggtttggggc atgttgggct ggcctacgcg ttactatttg catctaaata
    19261 taaagttgtt gcatatgata tagattctgt aaaaataaat aatttaaaaa agggcactct
    19321 tccatctaaa aatgaagagc ttatgaagtt tttttgcgag aataacttaa atattacttt
    19381 ttttgataca ttttctgaaa ttaaaaataa tattgattat tatattattg cgcttccgac
    19441 agattatgat gagaaaattg gtagttttaa tacatatgaa atcgaacaaa cggtatcgaa
    19501 gattctgagg gtaaaaccta atggaaagat tattttaaag tcaacagttc cgatcggctt
    19561 ttcaaacaaa ttaaaaaggc tgtttgatac aaaaaatatc atttttgtcc ctgaattttt
    19621 gagagaaggt tgttctatat atgataattt atatccaagt cgcatagttg ttggagatga
    19681 gacagttgaa ggaagaaaaa ttgcagagtt gttcctttcg attagtactc atagtactgc
    19741 caatattaaa aatgttatgt tagtttctcc tactgaagca gaagcaatta agcttttttc
    19801 taacacattc ttagctctcc gtgttgcttt ttttaatgaa ctagattctt ttgctgagag
    19861 gagaagttta aatgctgaag ttgtaataaa aggtgtttgt ttagatccaa gaattggaaa
    19921 tttttataat aatccttctt ttggatttgg aggatattgt cttcccaaag atactagaca
    19981 attaaaaaaa gaatttatag aaataaatgc cccagtgata gaagcgattg atatttcaaa
    20041 cacaaataga aaacagttca tagttaaaca aatattggaa cgaaagccaa agatagtagg
    20101 aatatataaa ttggggatga aatataattc agataattac aaagagtcag ctattttaag
    20161 tataattaat gaactattga ttgtcggtat aaaaatttta gtatatgaac caaatttaaa
    20221 cgttagtata gataacgtaa tttttgaaaa gaattttgaa ctatttataa aacaaagtga
    20281 tctaattgtt gcaaatagat gggatagggg ccttgaagct tataaagata aagtttacac
    20341 aagggggatc tggataagag attaactatt gatattaaaa aggcaataat ttataaaatt
    20401 tgtacaaaaa aatgttaaat tttcacattt tcatagtata ctgtttaata gaaagtaggt
    20461 tctttgtaac cgctccatta taaaatcctt tcactcttcc ggtatactat taggaaaaac
    20521 ataactggag gatattttga gctcacacct catcgttcca gtggctgttc cccaagctcg
    20581 tgtactgccc aaaaaagtta gacattctat ttagaacgag gattgagttc tgtattgtac
    20641 aaggctcggt ccttttagag tcagcttaag gctggctttt tcaatcacca aagtgtcaga
    20701 atgttttgac aaatgaacac aaataatgat ataatatgca aaagctagga ggtggtagga
    20761 tgattgaaaa aatggaactg ggggaatttt acaaggaatt gcgcttggcg agaaagctca
    20821 agcagtcaga tgtggcttgt gctggactaa cagcctctca gttgtccaag tttgaactag
    20881 gacagtctat gctgtctgca gacaagctga tcctagccat ccaagggatc aatatgaatt
    20941 ttgatgagtt tgggcacaaa ctcaacaact atcaagaatc tccacatatg cgaattggta
    21001 gaagggttgt ggattgcttt tcccatcagg atatagctgc tttagagcag ctattggagg
    21061 aagtcgatca agaacagatg gcgcagacct atcgtcgttt gaatgccatt gtgattaaaa
    21121 atgcactcca ttccttagat aaaagctacc cgctaacaga ggaggatagc gagtttttga
    21181 ctacctacct ctacgctatt gagtcttgga cctggtttga actctatctt ttttgcaata
    21241 ctatgccctt cttgagcaat caagatctga tctttttatc aacctcctta ctcgaaaaat
    21301 ccaaggaatt taaagagtta gtacacaatc gatggtatat gaaaagtggt tatcttaata
    21361 tcatctcaga acttatggag cgcaagctat tttcttatat tccaatcttt gaagctgagc
    21421 tggagcgcat gctccgtcca tacgatgttt ttgaaaaagt attgtggcag tttttaaaga
    21481 aaatgcagat ttttcttcaa accaaaggaa gcaatcaaaa agagattgaa cactttatcc
    21541 aatctctgca agtattagaa aatccacaat tgacagccct ttttgaattg cgtttgcagc
    21601 aatacaaaga gcttatcgat tagttagaaa tgggaaaaag ataataatat cagcaacgat
    21661 cgtcaataat gttaaaactt gtttcttcat attacttccc tcctcattag taataacttt
    21721 attataccag ggaaataatc aaatctacca aaatcgcaaa tctgaaattt ctataagaaa
    21781 aaatatcaaa tatgcgattt tctaaaataa gccaatttcc gtgttatact gtccttgtaa
    21841 aacatttgaa gcaaatccta ggtcgcagaa gtggtttaca aatgaagata attgaaggag
    21901 tgtaaaagat gttaaattta caatttgcag aaacaatgga attgacagaa gctgagttgc
    21961 aagatgttag aggaggcaac ctcgtaaatt ctatgggagg tggtggaaga agtggtatat
    22021 ctggttgggg cgtcccagga atttaccctg gttggggcaa tcaagggatg agtcctaatc
    22081 gtggagcttt tgattggact atagatttag cagatggatt gtttggccgc cgtagaagat
    22141 aggctcttat aggagataat aggatgaaga aaatgaaaga agtgaaattt cacctagcaa
    22201 ctggcttgtt gattttgact tattacctca tttttaatgt cacatcagac ttagatttta
    22261 tggttgcttt gtctgataat atgtactatg tgttccaagt tttattggta cttattctgg
    22321 gaactatagc tacaattgct tttgtcaaaa gtgaacattg gaaagagtgt ggtcgtttcc
    22381 agtttcgttg gtcttacctg ggtgttttcc ttctttcttt tttcttattg ttcgtgtggg
    22441 caaatctaac aacctatatc tttcctcgta cccagaatgg aagtacagtc gtagaagtag
    22501 ccaccagttt aacaggaatt agctattttg ttacgcgaat actttatact agtattatcg
    22561 cacctgtatc agaagaggtt gtttgtcgtg gtcttttgat gacaagttta tctaaagtta
    22621 agagatacta tcttgatgtt cttgtttccg ctgccatatt tggcgctatg catgttttgc
    22681 agtatggttg gataacgaca gatttcataa agtattttgg aatgggcttg atattttgta
    22741 tgatgtttcg ctacacccga tccatctatt gggctatagc tctgcatgct tcatggaata
    22801 gcttcttact cattgttact ttattggtat ttggatatta gaaaggtgat atatgaaaaa
    22861 gataatctca caccgctact ttattatagt ttttctacta gttattgctg accagaagtt
    22921 cagtgtttta gttttacgca gcgaccttgt tgctgggcta tctgactttg cctattatct
    22981 gtcggatatg atgttgaatt ttcttgtggt tttatttgct cttattgcta tgatttggtc
    23041 ggggaaatgg cagaaaatca atagtagaaa gtttaaagga tcctatcttt tctattcctt
    23101 cctagctctg cttgcttttg ttgcttggaa ttttgtcacc ttttttcttt tcccacctac
    23161 tcgaaatgaa atttcttatc aacatgctgc tcctactttt acaggagcta cggcattttt
    23221 gatgtatttt ttttatcctg tgattgcagg tcccattttt gaagacatga tttatcgtgg
    23281 attggtgatg acagctctgg aaaaaggaaa gaaatggggg ctagatgtac ttggttctgc
    23341 tattttattt ggggtctcgc acattagtaa tcacggttgg gtcttgacag actttttcgt
    23401 ctatatgggt ggcggactta tatttgcagt cttatttaga atgacaaagt ccatttattg
    23461 gcctattggg ctgcatatag tctacaacgg cattggtcag cttttgatgt tactgtaatt
    23521 ttggttgtta gtagtatcgc ggtctatttc tggggaaaga ttcccatttg aacttaagaa
    23581 ggagttgtga tgaaagtatt tcttcaaaat agagatttta ggcaattaac tatcaaccag
    23641 tggatttcaa cgcttgggga tacgattttt tatctggcct tcctgaatta tgtggcagat
    23701 gcgtcttttg cccctttggc gattttactt atcacgattt cagaaaccct tccccaagtt
    23761 ctacaaatct ttctgggagt tttggcggat tttcaacatc atcgtgtctt gaaatacaca
    23821 gtcattagtt ttacaaaatt tttgctttac tctatagtgt ccctatcgct ttcagggcag
    23881 tctttttcct tgttgctagt aacctttatt tgtctgctta acctcttgtc tgacacattg
    23941 agttattttt caggcgccat gctcactccg attttcatta gaattattgg gcaagaccat
    24001 ctggcagaag ctattggatt taaacagtca actgttagtt tagtgaaaac aatcagtaat
    24061 atcctaggag gagtcttact aggcattcta tccatccagt ttatttcctt actgaacgct
    24121 cttacctttt taatcgcatt tttaggtatc ctcttcataa aaactgacct cttgaaagta
    24181 gaaaaaacga ttagctatca agaaggactc tctgtaaaat ccttttgcca gcatttgctc
    24241 caatcatcga aattgatatg gaatatgaat aaggtgctct tggttttgtt tattatctct
    24301 actagtcaag cagtgataaa tgttacggtt cctatttcca ctctattttt aaggaaccag
    24361 ccctttttga atttacaaac tggtcaatct cttgccttgt tagccacact agaattatca
    24421 gcccttattt tgggaagtct gatgagtggc tatctgcaac ataccatttc cataaaaata
    24481 gccctgtatg cttcactcct actccaatta ctactcctag tgggctttgc gacagctcat
    24541 tttggcttga ttctgatctt tagctttttg gatgcctttt tcgcgggtat tctctctcct
    24601 agattgcaag aactcgtctt taaacaaata cctgaggagt caatgggagc agttcaatct
    24661 tctatcggtg ccattacggt tgttttacct agcttattta caatagcttt gggaaccatt
    24721 gctactagct ttggaactct ggcagttagc tttgttttat tactatttct tctagttgcc
    24781 tttgtcatgc ttctgaatat tcgtgaaagt atttagtgga gaatttctat aatatatgtt
    24841 tgagactgga ttgccagtct ttttatgatg gtcaaaatca acagactttt tctcttttct
    24901 gaatgtgtta tagtagactg aatctaaaat agtacgaaat aattgctaaa acatttatag
    24961 aaattaattt tactttccca atcgatttgt tctcatctta tttcaatctg ctatataata
    25021 gtccatgctg tggctggatt cttttcagcc tacttatact cttcgaaact ctcttcaaac
    25081 cacgtcagct tcaccttgcc gtaggtatgg ttactgactt cgtcagttct atccacaacc
    25141 tcaaaacagt gttttgagct gacttcgtca gttctatctg caacctcaaa acaatgtttt
    25201 gagcaacctg cggctagttt cctagtttgc tctttgattt tcattgagta ttattaagac
    25261 aatatgagga gaaagatgaa agaaaaagga ttttaggagg gggcgcaggc agccatgcca
    25321 acggctcttg gctatgtcag tatcggcctg gcctgtggga ctatcggtgc gccctatgtg
    25381 acacctgttg agatgggctt gatgagtctc tttgtttatg ctgggagtgc ccagtttgcc
    25441 atgttggcac tgattgtggt tcaagctcct gtggcagcta ttgctatgac ggtttttcta
    25501 atcaacttgc gtctcttttt gttgagttta cacgcatcga cttatttccg tcataccagt
    25561 ctttggtaca atatcggtat gtctagtatc ttgacagatg agacctatgg cgttttgatg
    25621 ggtgaattgg cccatacaga caaggtaaat cctatgtgga tgcacggaaa caatcttaac
    25681 agctatgtgg cttggtttgt ggggacagta gtcggaacgg ctctgggtgg cctgctacca
    25741 aatccagaaa tctttggctt ggattttgcc ctggttggga tgtttattgg tatttttgct
    25801 tcgcaatttc agattatgca aagacggatt cctgtccgca atctgctcat tatcctagca
    25861 gttgttgcgg tgtccttctt tttgctcttg acagtggtgt ctcagtcact agctgttctg
    25921 tttgcgacgc tacttggttg tagcatgggg gtggttttag atggtcagta agtatctttt
    25981 attagcagtt attttctctg acttggtgac ttggattctc cgtatgattc ccttcatctt
    26041 agtcaagtat aagggcttgc ctgcaatcgt tgagcgtttt ttgaagttct tgcccgtttc
    26101 cattatcttt gccttgattc tttcaagcgt agtgacaggt aaggttggga gccttcctca
    26161 aattaaatgg ctagacttct tagccgtctt tccaacagct tgggtagcct ttcgctaccg
    26221 caatctagtc ggaacagttc tctttggagt agtcttgatt gccgtcttgc gtttggtctt
    26281 ttaaatcagc cataaagaaa acctatcaca gatatatata tcatataatg gtgtaaatga
    26341 tttttttctg ttaagattat aaggtattct attttggagg aaatgacatg aaaaaaatcg
    26401 ttaaatactc atctcttgct gccctagggc ttgttgctgc aggtgtgcta gcagcttgct
    26461 ccggtggtgc taagaaagaa ggacaagcag ctagcaagaa agaaattatt gttgcaacta
    26521 attcttcacc aaaaccattc aactatgaag aaaatggcga attgactggt tacgagattg
    26581 aagtcgttcg cgctatcttt aaagactctg ataagtatga tgtcaagttt gagaagacag
    26641 agtggtcagg tgtctttgcg ggtcttgacg ctgaccgtta ccaaatggct gttaacaaca
    26701 tcagctacac taaagaacgt gcggagaaat acctttatgc agccccaact gttaaagacc
    26761 ctaacgttct tgtagtcaag aaagacgatt ctagcatcaa atcgcttgat gatgttggtg
    26821 gaaaatcaac agaagttgtt caaggaacaa catctgctaa acagttagaa gactacaaca
    26881 aacaacactc agataatcca actatcctta actatactaa agcaaactta caacaaatca
    26941 tgggccactt gagcgatggt cagtttgact acaagatttc tgataaaatc actgttgaaa
    27001 cagtcatcaa gaaccaaggt ttggacaact tgaaagtcat cgatcttcca agcgaccaac
    27061 aaccttacgt ttacccactt cttgctaaag gtcaagatga gttgaaaaca tttgtagaca
    27121 aacgtatcca agaactctac aaagacggaa ctcttgaaaa attgtctaaa caattcttcg
    27181 gagacactta cctaccggca gaagctgata ttaaataatt tcttgaaatc atccattctg
    27241 agtaagatgg gtgatttttc agttcgctac cgcaatctag tcggaacagt tctctttgga
    27301 gtggtcttga ttgccatctt gcgtttggtc ttttaaatta cccataaaaa aaacttatca
    27361 cagagataga tatcatataa tggcgtaaat gctctttttc tgttaagatt ataaggtatt
    27421 ctattttgga ggaaatgaca tgaaaaaaat cgttaaatac tcatctcttg cagcccttgc
    27481 tcttgttgct gcaggtgtgc ttgcggcttg ctcaggtggt gctaagaaag aaggacaagc
    27541 agctagcaag aaagaaatca tcgttgcaac caatggatca ccaaagccat ttatctatga
    27601 agaaaatggc gaattgactg gttatgagat tgaagtcgtt cgcgctatct ttaaagattc
    27661 tgacaaatat aatgtcaagt ttgaaaagac agaatggtca ggtgtctttg ctggtcttga
    27721 tgctgaccgt tacaatatgg ctgtcaacaa tcttagctac actaaagaac gtgcggagaa
    27781 atacctctat gccgcaccaa ttgcccaaaa tcctaatgtc cttgtagtga agaaagatga
    27841 ctctagtatc aagtctctcg atgatatcgg tggaaaatcg acggaagtcg ttcaagccac
    27901 tacatcagct aagcagttag aagcatacaa cgctgaacac acggacaacc caactatcct
    27961 taactatact aaggcagatt tccaacaaat catggtacgt ttgagcgatg gacaatttga
    28021 ctacaagatt tttgataaaa tcggtgttga aacagtgatc aagaaccaag gtttggacaa
    28081 cttgaaagtt atcgaacttc caagcgacca acaaccgtac gtttacccac ttcttgctca
    28141 gggtcaagat gagttgaaat catttgtaga caaacgcatt aaagaactct acaaagacgg
    28201 aacgcttgaa aaattgtcta aacaattctt cggagacact tatctaccgg cagaagctga
    28261 tattaaataa tttcttgaaa tcatccattc tgagtaagat gggtggtttc tcagttttta
    28321 gggatatagt tttaaactat atatctgact atctaataac aatttgtgaa atcaaacaaa
    28381 ttgtgagata ctagtacggt attattttta aggagaaaga atcatgaaaa tcaaaaaatg
    28441 gcttggccta gcagcccttg ctacagtcgc aggtttggct cttgcagctt gcggaaactc
    28501 agaaaagaaa gcagacaatg caacaacgat caaaatcgca actgttaacc gtagcggttc
    28561 tgaagaaaaa cgttgggaca aaatccaaga attggttaaa aaagacggaa ttaccttgga
    28621 atttacagag ttcacagact actcacaacc aaacaaagca actgctgatg gcgaagtaga
    28681 tttgaacgct ttccaacact ataacttctt gaacaactgg aacaaagaaa acggaaaaga
    28741 ccttgtagcg attgcagata cttacatctc tccaatccgc ctttactcag gtttgaatgg
    28801 aagtgccaac aagtacacta aagtagaaga catcccagca aacggagaaa tcgctgtacc
    28861 gaatgacgct acaaacgaaa gccgtgcgct ttacttgctt caatcagctg gcttgattaa
    28921 attggatgtt tctggaactg ctcttgcaac agttgccaac atcaaagaaa atccaaagaa
    28981 cttgaaaatc actgaattgg acgctagcca aacagctcgt tcattgtcat cagttgacgc
    29041 tgccgttgta aacaatacct tcgttacaga agcaaaattg gactacaaga aagcactttt
    29101 caaagaacaa gctgatgaaa actcaaaaca atggtacaac atcattgttg cgaaaaaaga
    29161 ttgggaaaca tcacctaagg ctgatgctat caagaaagta atcgcagctt accacacaga
    29221 tgacgtgaaa aaagttatcg aagaatcatc agatggtttg gatcaaccag tttggtaata
    29281 agaaacaggg aggtgggaga gaaaattcca cctcttgctt ttgtatagag tatagattgt
    29341 aaagaagact attcgttcat agaaaggtag agagaatatg gtttttccta gcgaacaaga
    29401 acagattgaa aaatttgaaa aggatcatgt agtccaacat tattttgagg ttttgcgtac
    29461 cttgatttct aagaaatcag tctttgccca gcaggttgga ctcaaggaag tcgcaaatta
    29521 tctgggtgag attttcaagc gtgttggagc tgaagtggag attgatgaga gctatacagc
    29581 gccctttgtc atggcacatt tcaagagttc gcgtccagat gccaagacct tgattttcta
    29641 taaccactat gacactgtgc cagcggatgg ggatcaggtc tggacagagg atccttttac
    29701 gctttcggtc cgcaatggct tcatgtatgg gcgtggggtt gatgacgaca agggtcatat
    29761 cacagctcgc ttgagtgctt tgagaaaata tatgcagcac catgatgatt tacctgtcaa
    29821 tatcagcttt atcatggagg gagcggagga atcggcttca acagacctag ataagtattt
    29881 ggaaaagcat gcagacaaac tccgtggggc ggatttgttg gtctgggaac aagggaccaa
    29941 aaatgccttg gaacagctgg aaatttctgg tggcaataag gggattgtga cctttgatgc
    30001 caaggtaaaa agcgctgatg tggatatcca ctcgagttat ggtggtgttg tggaatcagc
    30061 tccttggtat ctcctccaag ccttacagtc tcttcgtgct gcggatggcc gtatcttggt
    30121 tgaaggcttg tacgaagaag tacaagagcc caatgaacga gaaatggcct tgctagaaac
    30181 ttatggtcaa cgaaacccag aggaagttag tcggatttat ggattggagt tgcctctctt
    30241 acaggaggag cggatggcct ttctaaaacg tttctttttc gagccagcgc ttaatatcga
    30301 aggaatccag tctggttatc aaggtcaggg tgttaagact attttacctg cagaagccag
    30361 tgccaagcta gaggttcgtc tggttccggg cctagaaccg catgatgttc tggaaaaaat
    30421 tcggaaacaa ctagacaaaa atggctttga taaggtagaa ttatactata ccttgggaga
    30481 gatgagctat cgaagcgata tgagcgcacc agccattctc aatgtgatcg agttggccaa
    30541 gaaattctat ccacagggcg tttcagtctt gccgacgaca gcggggacag gacctatgca
    30601 tacggtcttt gatgccctag aggtaccaat ggttgcattt ggtctaggaa atgccaatag
    30661 ccgagaccac ggtggagatg aaaatgtgcg aatcgctgat tattacaccc atatcgaatt
    30721 agtagaggag ctgattagaa gctatgagta gagatattat caagttagat cagatcgatg
    30781 tgacttttca ccaaaagaag agaaccatca cagcggttaa ggatgtgacc attcacatcc
    30841 aagaagggga tatctacgga atcgttggat attctggagc agggaaatca acccttgtac
    30901 gggtgattaa cctcttgcaa aaaccatctg cagggaaaat taccattgac gacgatgtga
    30961 tttttgatgg taaggtcacc ttgacggcag agcagttgcg tcgtaaacgt caagatatcg
    31021 ggatgatttt ccagcatttt aacctgatga gccaaaagac agcagaggag aatgtagcct
    31081 ttgcccttaa acactctgga ctcagcaagg aagaaaagaa ggctaaagta gctaagttgt
    31141 tggacttggt tggtttggca gatcgtgctg aaaactaccc ttcacaacta tctggagggc
    31201 aaaaacagcg tgtggcaatt gcgcgtgcct tggccaatga tccaaaaatc ttgatttcag
    31261 acgagtcaac ttctgccctt gatccgaaga caaccaagca gattttggcc ttgttgcaag
    31321 atttgaacca aaaattaggc ttgactgttg tcttgattac gcatgaaatg cagattgtca
    31381 aagacattgc caaccgtgtt gcagttatgc aggatgggca tttgattgaa gagggtagtg
    31441 tgcttgaaat cttctcaaat cctaaacaac ctttgactca agactttatc tcaacagcta
    31501 caggtattga cgaagccatg gtcaaaatcg agaagcaaga aatcgtggaa cacttgtctg
    31561 aaaacagtct cttggtgcaa ctcaagtacg ctggagcttc aacagacgag ccacttttga
    31621 atgaattgta caagcattac caagtaatgg ctaatattct ctatgggaat atcgaaattc
    31681 tcgatggtac tcctgttgga gaattggtgg tggtcttgtc aggtgaaaaa gcagcgttgg
    31741 caggtgccca agaagccatt cgtcaagcag gtgtacaact aaaagtattg aagggaggac
    31801 agtaagatgg aatcattgat tcaaacctat ttaccaaatg tctataaaat gggttgggct
    31861 ggtcaggcag gctggggaac ggctatctac ttaactcttt atatgacagt tctttccttc
    31921 attatcggag gcttcttggg gctagtggca ggtctctttc tcgtcttgac agcgccaggt
    31981 ggtgtcttgg agaataaagt cgtattctgg attttagaca aaattacctc aatttttcgt
    32041 gcagttccct ttatcatcct cttggcaatc ttgtcaccac tttctcactt gattgttaaa
    32101 acaagtatcg ggccaaatgc agcccttgtc ccactttctt ttgcagtctt tgccttcttt
    32161 gcccgtcagg tgcaggttgt cttggctgaa ttggatggcg gtgtcattga ggcggctcaa
    32221 gcgagcggag cgactttctg ggacatcgtg ggtgtttacc tatcagaagg tcttccagat
    32281 ttgatccgtg tgacgactgt gaccttgatt tcccttgttg gggaaacagc tatggccggt
    32341 gcggttggag ctggtggtat cggtaacgta gccatcgctt atggatttaa ccgctacaat
    32401 cacgatgtga ccatcttggc aaccatcatt atcattttga ttatctttgc aatccaattc
    32461 ttgggagatt tcttgactaa gaaattgagc cataaataaa aaagagccgc gtggctcttt
    32521 ttaactgatc agattttctg tgcaaatttt ttactcaagg cttgtccaat caaggcaccc
    32581 actagggctc cgatgacaat acttgcgata aatagaagga cagttccagg gtttggagcg
    32641 accatgatgc ggtcgatata ttcttgggat tttcctcttg ccagaagagt agccatatag
    32701 gctttgggcg caatccacat aagcaagatt ggtcctgttg tactaaaggc gaaaataatg
    32761 aaagaaagga agttctttgt tttgtccttg tattttccta aatgagctac tccatctgct
    32821 aggaggccac agataattcc aggaaggaag gaaccagcac cgtgtttagt tcccaagaaa
    32881 aagagggcaa tgacaaggcc gatagtggta atggctccaa agcgcggaac ttttgcgact
    32941 aggatcatat agacgctacc gccgacaagg gcagtaaagg caggcgcata aaacatgttt
    33001 ccagtttggt caaagagatt gcccaaaagg acaccaatcc ccatgcagag gaagtaaaga
    33061 actgcaaaaa gcagtgtagt taagatagat ttcttcatga attgtctcct gataattttt
    33121 tcacaattct cattttacca tggtttggtg ggattgtaaa tggatactag aagtttttga
    33181 aaacgcttga aatatgatat aatggtttca tagttatttt taggggaata tcatgggtag
    33241 atttttagac tttgtcttta atcgtttctt tttagggatg attgcgacag ccttcttttg
    33301 gctattaact ttagcaggag ggattatcct tggtctagcg ccggctagtg ccaccttgat
    33361 gagcttatat gcagaacatg gttatagctt tcgggaatac agtttgaagg aggcttggtc
    33421 tctttacaag caaaattttg tctcaagcaa cctgattttc tatagctttt taggtgtggg
    33481 tctagttttg acctatggtt tgtatctctt ggtgcaattg cctcatcaga ctattgttca
    33541 tttgattgcg acccttttga atgtcctagt agttgccctg atctttttgg cttatacagt
    33601 atctttaaaa ttacaagttt attttgcctt gtcctatcga aatagtctca aattatcctt
    33661 gattggcatc tttatgagtc tagcagctgt ggccaaggtt ctccttggga ctgtgctact
    33721 tgtagcaatt ggttactata tgcctgccct gctatttttt gtaggaattg ggatgtggca
    33781 tttctttatc agtgatatgt tggaacctgt ctatgaaatc atccatgaaa aattggcgac
    33841 aaaatagaat gaagcagttt tggctacata cgcttctaag aacctatagt tcagtgatga
    33901 tcattatcat tgcgagtttt gcaatcttac tctcttacgc tgactgggat tcacgtgaaa
    33961 aggaagccca gagagtagcc cagcgtgtaa ctgctagaac agtgagtgaa attgaatatt
    34021 accatagaga gtcaacccag atagctcagg ctttagttga aaatcaagct cgtattgagg
    34081 gaatctataa atactttagc cttagcatgc cagactattt ttactggcaa ttagagcgga
    34141 aagcttcgcc ttatatatca gtctctctgt atgaaaatgt tgatgacctc tatgttcgaa
    34201 atgattttgt aactggggtg gccattgctt ttcaagatta caaggaagtc tatgtttcta
    34261 ctaaagacaa acgtagtgga gaaaaaatca gggctgagga tttcaaacca gcaggaaata
    34321 gttttgccat tccggtgtca gatccagtgt cagatcaaga tttaggagtg atttacatct
    34381 ccttggatcc tgctgtttta taccatgcca ttgataatac tagaggtcat actccgatgg
    34441 cagtaacagt gacctcacct tttgatacgg agatttttca tattggtgag acagttgata
    34501 gggagagtga aaattggcta gttggcttaa cttctcatgg atatcaggtt caggtggcag
    34561 ttcctaaaaa ctttgtttta caaggaacag tgactagctc tgctttgatt gtgggtttga
    34621 gccttctctt tattgtcatt ctttatctga ctttgaggca gacttttgct aattaccaaa
    34681 agcaggtagt ggatttagtg gaatccattc aagtcattgc tcaaggcgaa gaggggcgtc
    34741 ggattgacat ttccgaaaaa gatcaggaat tactcctaat cgcggagacg accaatgata
    34801 tgttggatcg attggaaaag aatatccatg atatttacca gttagagctt agtcaaaaag
    34861 atgccaatat gcgagccttg caggcgcaaa tcaatcctca ttttatgtat aatacgctgg
    34921 agttcttgcg catgtatgca gttatgcaga gtcaagatga gttggcagat atcatttatg
    34981 aattcagtag tctcttgcgt aacaatattt ccgacgaaag agagaccctc ctcaaacagg
    35041 aattagaatt ttgccgtaaa tacagctatc tctgcatggt tcgctatccc aagtccattg
    35101 cctatggttt caagatagat ccagagttag agaatatgaa gattcccaag tttaccttgc
    35161 aaccgctggt agaaaactat ttcgcgcatg gtgttgacca caggcggaca gataatgtga
    35221 ttagcatcaa ggctcttaaa caggatggtt ttgtggaaat tttggtggtc gataatggta
    35281 gaggaatgtc ggctgaaaag ttggcaaata tccgagaaaa attaagtcag aaatattttg
    35341 aacaccgagc cagctacagt gatcaaaggc agtctatcgg gattgtcaat gtacacgagc
    35401 gttttgtgct ctattttgga gaccgctatg ccattacgat agagtctgca gagcaagccg
    35461 gtgttcagta tcgtattaca attcaagatg agtagaaagg gagaaaatgt ataaagtatt
    35521 attagtagat gatgagtaca tggtgacaga aggtctgaag cgtttgattc cctttgataa
    35581 gtgggatatg gaggtcgtcg caacagccag tcatgccgat gaagctctag aatatgttca
    35641 ggaaaatcct gtcgatgtca tcatttccga tgtcaatatg ccagacaaaa cagggcttga
    35701 tatgattcgg gagatgaaag agatcttacc agatgctgcc tatatcctgc tctcaggtta
    35761 tcaggagttt gattatgtaa aaagagcaat gaaccttagt gtggtggact atttggtcaa
    35821 gcctgttgat aaggtagagc tgggaaatct gctggagaag attgcaggtc agctcggcga
    35881 gagagggaag aaaagtcaga ctcttagtca agaattagac gaggctggat ttgttagtta
    35941 tttaggggat aaggagaatt ggtggatagg tctatccaag gaaaaacaag gttccttcac
    36001 cattccctac tatgtcttgg gccaagactg gcagattttc atttctgacc aacccctaga
    36061 tggtttagtc gttacacctt ttgaagctcc ttatcaagaa cactttgaac gctggaagct
    36121 gaatgctgag aaaaccctct tttacggttc tgtaaatttg cagcagtctg agagtctctt
    36181 tgcctattac gaaccgattt atagggttat cattcaggga aatctcaatc aaatcgtaga
    36241 agagttaaat ctcttggaga aggtagttct tgaaaatacg ccgcgtgttc cgattactaa
    36301 acagcttttt attcagtttg tcatggatgt tttccattta tttgaacatc tcaaagctga
    36361 tgacctgaca gacatcgtca aaaccattca tgctattcaa tccttcgatg aattggttcc
    36421 ttatatcaag gaaactctga gcagcttttt cggtcaatac cgtatgaatg aaaatgtggt
    36481 cagtgtgctg gaagtcattg gttgtgatta ccaaaaagag ctttccctca aggatatcag
    36541 taaggctctc tttatcaatc ctgtctatct agggcagttg attaagcgtg aaaccgattc
    36601 gacttttgca gagttactaa acaaacaacg tattaaggct gcccaacaac ttttgctttc
    36661 aactagtgac agcatcgaag atatttgtta tgctgttggt tacagtaacc ttggatattt
    36721 ctataaagtt ttccgaaaat tgtgcggaaa atcgccaaaa gcctaccgaa aacaggtaga
    36781 aactatacta taagatttgt attcctttac aaaatgtgct ataatataaa tattattatt
    36841 aggaggttct atcatgaaaa agaaaccaat ttatctatgg gtcttgctaa tcttgtctgc
    36901 ccttatttca gttccgtctc tgtttggaat tgtgagtccc ttgcctagta aagaagccct
    36961 tcgtactgct cagaaacaag ttgcaggggt caatgctcag caattagaag accagcttaa
    37021 ttatacctat agagtagcag aagcatctca ttctattttt aatgttgctt tgattgtgct
    37081 atctactatt ttagtggtcg tagcgattgt cttccttgtt cgtaaaaatt tgcaatatgc
    37141 aaactatact tacgttggct atgttttgtt agctattatt ggttcgattt atggctatgt
    37201 tggtttacaa gacgctgtgc agttggttca agatgagagc atgcgtttga cagtgagtat
    37261 tggttcaaaa gctgttagca ttttctatat cgtcatcaat gttctcttcc tagcccttgt
    37321 cttctataag atgtggcgac aacagaaagc ctcggcagaa gaagaggaaa cagaagagct
    37381 tgcctaagta ttgacaaaaa agaactatca agatacaatc ttggtagttg ttttttgatt
    37441 atagataaaa tcatggaggt acatatgaag ataatttctt tagtttatat tagtttgagt
    37501 ggcaacactg aaagttttgt gacgcgcttg aaagactatc tcttgtccca gtacaaaggg
    37561 attgaggttc aaaagattca tatcaaggat ttagtcaagg aaggcaaaaa tttctatgaa
    37621 atggaccatc cctatgtcgc ttttttgccg acctatctcg aaggtgggaa tggcgtggat
    37681 aacggagatg ttgagatttt gacgacaccg gtgggagatt ttattgccta tggtaacaat
    37741 gctagtaagt gttttggtgt ggttgggtca ggaaatcgta actttaataa ccaatactgc
    37801 ctaacagcca agcaatacag tcaacgcttt ggctttcctg tattggctga ctttgaaatg
    37861 cgaggcatgc tggaagatat caaacatgtc gcagctatta tcgcagattt gtatgagttg
    37921 gaaaaggaga attaatactc aatgaaaatc aaagagcaaa ctaggaagct agtcgcaggt
    37981 tgctcaaagc acagctttga ggttgcagat agagctgacg tggtttgaag agattctcga
    38041 atagtataaa attcttataa gaggtggttg aagttgttca actgtttttt gagtataaac
    38101 agtctttaag aacgtaaaaa agcataagtt caggtcttca aaaccttgtt cttatgcttt
    38161 ttatcataga aatatttgct gaattttctc ttgaaatgaa accttatctt catctcgcgc
    38221 ttgtccctta ccctgctttt ccgattgcga gtgcgtagat aaagaagatg gcgaagccaa
    38281 agaggaaaat caatcccgca atggcaaggt gtttgagcca agaaggaaga tttttgtttt
    38341 cacgcgttac caaggcgtaa ttcaaaagag caaagaaagg tgttgtcagg aaagagccaa
    38401 tcatggcaaa gcggagcatg gttgaaacct gaccagagaa gaacttgata atgacgatac
    38461 cgatgatagc agtgatggtc atccagatgt tcaaagattt acgattgtcc tctttttgac
    38521 tgattagcag tcggagagat tcctgattaa cgcgagaata gccatcgata acagttataa
    38581 ctgttccaaa gatacagagg aaggcaataa aggtaatcaa gtaacgggac cattcgccaa
    38641 gaacagaggc atacatgccc acgaattgag agatgtattt ggctgaagca gcttcaaccg
    38701 cctgccctgt aggatactga atcagtgctc ccagtgccac aaagaagacg gctaggatag
    38761 ctgttccaat ataaccagtg ttaaagtcaa acagagcgtc ttctgtgtta aagttgacgg
    38821 tctttctctt ttcagctgac caaagtgaat tgatggctga aatttcaata ggagccggca
    38881 tccatcctag gagggagacg atgaagggca gagctgccat ttgccaaggt gtcttctcga
    38941 caaaatcaga actgtattct ggatgcttga ccgccgcaat gataactgcc agaacagtcg
    39001 caatggttaa ggcagacata atccatttga ccatgccgtc taaaagtttg tagcctccaa
    39061 agagtagcat agcccaaatg attgcaacga gaatgaggga ccactgagta atgctaagtc
    39121 caatcattgg gaaggcactg gcgatgatag ctgagcacag aatggcaaca ccagccgtgt
    39181 tgaccatagc cgaaaagaca ttgaggataa agaaaatcca gagatagagt tttccttttt
    39241 cggcataacc ttcaaccaaa gtctttccag tatcagctgt gtattcagca ccaaaacgga
    39301 aaaatggata tttaaagaca ttggctaaga tgaccaagag aagtagagac caaccgtaag
    39361 aaccgccagc ttgagttgag gatacaatgt gggaacctcc aacagcggca gttgccatta
    39421 ggattccagg tcccattgct tttagcttgc ttgcccaggt tgattgattt aaggaaatag
    39481 cttgcgacat gataaatact cctttttgaa ttttcagaat aatctgtata tgtaatctat
    39541 attctacaaa aaattttgga aaaatgcaag aatattttga aaaaagatag aaaatttaca
    39601 aagaaaat
//
LOCUS       DAVBBO010000014        38639 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ST1
            SAMEA2066453-rid20184263.denovo.014, whole genome shotgun sequence.
ACCESSION   DAVBBO010000014 DAVBBO010000000
VERSION     DAVBBO010000014.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2066453
            Sequence Read Archive: ERR351777
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 38639)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 38639)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980402.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980402.1
            Genome Coverage       :: 176x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:17:33
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,141
            CDSs (total)                      :: 2,104
            Genes (coding)                    :: 1,953
            CDSs (with protein)               :: 1,953
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 16S)
            partial rRNAs                     :: 1 (23S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 151
            CDSs (without protein)            :: 151
            Pseudo Genes (ambiguous residues) :: 0 of 151
            Pseudo Genes (frameshifted)       :: 73 of 151
            Pseudo Genes (incomplete)         :: 76 of 151
            Pseudo Genes (internal stop)      :: 40 of 151
            Pseudo Genes (multiple problems)  :: 32 of 151
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..38639
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2066453-rid20184263.denovo.014"
                     /strain="ST1"
                     /db_xref="taxon:1313"
     gene            186..632
                     /gene="rplM"
                     /locus_tag="VQU30_000713"
     CDS             186..632
                     /gene="rplM"
                     /locus_tag="VQU30_000713"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003083327.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L13"
                     /protein_id="HET2446855.1"
                     /translation="MNKTTFMAKPGQVERKWYVVDATDVPLGRLSAVVASVLRGKNKP
                     TFTPHTDTGDFVIVINAEKVKLTGKKATDKIYYTHSNHPGGLKQISAGELRSKNAVRL
                     IEKSVKGMLPHNTLGRAQGMKLKVFVGAEHTHAAQQPEVLDISGLI"
     gene            652..1044
                     /gene="rpsI"
                     /locus_tag="VQU30_000714"
     CDS             652..1044
                     /gene="rpsI"
                     /locus_tag="VQU30_000714"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002942223.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S9"
                     /protein_id="HET2446856.1"
                     /translation="MSQAQYAGTGRRKNAVARVRLVPGTGKITVNKKDVEEYIPHADL
                     RLVINQPFAVTSTVGSYDVFVNVVGGGYAGQSGAIRHGIARALLQVDPDFRDSLKRAG
                     LLTRDSRKVERKKPGLKKARKASQFSKR"
     gene            1393..1602
                     /locus_tag="VQU30_000715"
                     /pseudo
     CDS             1393..1602
                     /locus_tag="VQU30_000715"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            1758..2096
                     /locus_tag="VQU30_000716"
     CDS             1758..2096
                     /locus_tag="VQU30_000716"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000176371.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antibiotic biosynthesis monooxygenase"
                     /protein_id="HET2446857.1"
                     /translation="MTLTIHVYYKGDGDCAIKFAREMLESGLVAEIRCQKGNLKYEYF
                     LPIEKEGIILLIDQWINQEALDEHHQSNTMQKILDLRKKYHLQMQVERYIEDDSGMPE
                     SDKSFIDTGN"
     gene            2286..3722
                     /locus_tag="VQU30_000717"
     CDS             2286..3722
                     /locus_tag="VQU30_000717"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001861533.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-glucosidase"
                     /protein_id="HET2446858.1"
                     /translation="MTTFKDGFLWGGAVAAHQLEGGWQEGGKGISVADVMTAGRHGVA
                     REITLGVLEGKYYPNHEAIDFYHRYKEDIALFAEMGFKCFRTSIAWTRIFPKGDELEP
                     NEEGLQFYDNLFDECLKNGIEPVITLSHFEMPYHLVTEYGGWKNRKLIDFFARFAEVV
                     FKRYKDKVKYWMTFNEINNQANYQEDFAPFTNSGIVYEEGDNREAIMYQAAHYELVAS
                     ARAVKIGHEINPDFQIGCMIAMCPIYPVTCNPKDILMAMKAMQKRYYFADVHVLGKYP
                     EHIFKYWERKGISVDFTDQDKEDLLGGTVDYIGFSYYMSFAIDSHRENNPYFDYLETE
                     DLVKNNYVKASEWEWQIDPEGLRYALNWFTDHYHLPLFIVENGFGAIDQVAADGMVHD
                     DYRIEYLGAHIREMKKAVVEDGVDLMGYTPWGCIDLVSAGTGEMRKRYGFIYVDKDDN
                     GKGSYNRSPKKSFGWYKKVILSNGESVE"
     gene            3774..4013
                     /locus_tag="VQU30_000718"
     CDS             3774..4013
                     /locus_tag="VQU30_000718"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000580385.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SemiSWEET family sugar transporter"
                     /protein_id="HET2446859.1"
                     /translation="MIGSIAAILTTFAFLPQVFRVVKTKDTGSIALGMYVMQVIGIAL
                     WLAHGIRIGDLPLILANSVSFLLSGIILFYKLKYK"
     gene            4143..4457
                     /locus_tag="VQU30_000719"
     CDS             4143..4457
                     /locus_tag="VQU30_000719"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003037418.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS cellobiose transporter subunit IIB"
                     /protein_id="HET2446860.1"
                     /translation="MAKALIICAAGMSSSLMAQKTTEFLKGKGKDIVVDAISATEGGK
                     AIAAAAFDLYLVSPQTKMYFKQFEEAGSKAGKPVVQIPPQAYIPIPMGIEKMANLILE
                     NI"
     gene            4575..6554
                     /locus_tag="VQU30_000720"
     CDS             4575..6554
                     /locus_tag="VQU30_000720"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001101767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BglG family transcription antiterminator"
                     /protein_id="HET2446861.1"
                     /translation="MNVLNIKEKDILQFLIKNKERFVTSKELAEYLSCSDRTVRNVLK
                     LIEKTMIIQGVRLISKQGQGYQIFFENQGAYQEFRQTYELEEDYTKTAVSKGDDRLVF
                     ILNKLLFEQVPVLFDDLADELYVSRSTLSHDFRKIRVMLSEYNLSIESRANKGVYVSG
                     EERDKRRFIINYFLENQFFKTIHCYVKFNFFAQTVPLEEFARIVLDECQEANLKLSDF
                     VLQNLVVHIALSVIRLKSGFEIKNIDCQMTDDAIERKVAQRILSKVREVTNQEFPVQE
                     IDYITLHLLAKSQQCQKNQKNISEEVLKKSLFKTFQNLGLDDMYNFSSDFQLIEGLIT
                     HLMTLQVRLESRITLNNPLVDEIKQNYSDIFFMTREILANMDKFLEWTISDDEVAYVS
                     LHFLAAMERSKESTKFNILAICATGFGAAQMLRNRLETEFGKRVEVVDVIGYYELNQE
                     KLKGIDFIVSAVDLSNLYFQIPVFKVSVFLKSDEMEMIRKAMDQMQVSSYVQSSKINK
                     FENNSFRQYFSKENFLICTESDKVNLLEKMVESLSVGESNEFEQSLLYGIKQREELSS
                     VVFSEKIAVPHPIQPFGTEGKVSVAICKDSLLWDNQSSYVQLVFLLSPSIYGNEGLAT
                     VTKKIVSLTENDELQNQLISCNNFEDFISIFEKIK"
     gene            6564..6878
                     /locus_tag="VQU30_000721"
     CDS             6564..6878
                     /locus_tag="VQU30_000721"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001070943.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS cellobiose transporter subunit IIA"
                     /protein_id="HET2446862.1"
                     /translation="MNQEELQVAAFEIILHSGNARSEIHEAFAKMREGSFDDAESKLN
                     QSNEIILEAHHAQTKLLQEYASGVEIKIEIIMVHAQDHLMTTMTLLEVAKEMLALYKK
                     VN"
     gene            6909..7415
                     /locus_tag="VQU30_000722"
     CDS             6909..7415
                     /locus_tag="VQU30_000722"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000358304.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2446863.1"
                     /translation="MDKKERQKIEQQRREMALTNTFFNRYLLLRYSIALFFFGNIYWL
                     LNQFINPSPIIIFPIMLIVFSILATVEQFKLYGNRKEKLGITLMFVRIQILISIGLLV
                     LTWTSWFKNLFPIFENNQVARLFVFVVLLLGLVLSLLDIRRIKKIYKRTDKAYQQFVQ
                     LEKNSLSL"
     gene            7495..8841
                     /gene="celB"
                     /locus_tag="VQU30_000723"
     CDS             7495..8841
                     /gene="celB"
                     /locus_tag="VQU30_000723"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002206206.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS cellobiose transporter subunit IIC"
                     /protein_id="HET2446864.1"
                     /translation="MDQQNGLFGFLENHVMGPMGKLAQFKVVRAITAAGMAAVPFTIV
                     GSMFLVFSILPQAFSFWPIVADIFSASFDKFTSLYMVANYATMGSLSLYFVLSLAYEL
                     TKIYAEEEELNMNPLNGALLALMAFVMTVPQIIFDGGMMKTVTSLKEGAVIADGWAMG
                     NGVARFGTTGIFTAIIMAIVTVLIYRMCVKHNWVIKMPEAVPEGVSRGFTALVPGFVV
                     AFVVIFINGLLVAMGTDIFKVIAIPFGFVSNLTNSWIGLMIIYLLTQLLWIVGIHGAN
                     IVFAFVSPIALANMAENAAGGHFAVAGEFSNMFVIAGGSGATLGLCLYIAFASKSEQL
                     KAIGRASVVPALFNINEPLIFGLPIIYNPALAIPFILAPMVTATIYYVANSLNFIKPI
                     IAQVPWPTPVGIGAFLGTADLRAVLVALVCAFAAFLVYLPFIRVYDQKLVKEEQGI"
     gene            9221..9397
                     /locus_tag="VQU30_000724"
     CDS             9221..9397
                     /locus_tag="VQU30_000724"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866213.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2446865.1"
                     /translation="MSLDIDKEKMTIMGIAFENRSVFKSVWYALSTNMIEGWRPTVSD
                     VEKLRDEALALGMT"
     gene            9807..12020
                     /locus_tag="VQU30_000725"
     CDS             9807..12020
                     /locus_tag="VQU30_000725"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000688702.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-xylosidase"
                     /protein_id="HET2446866.1"
                     /translation="MKIFKGEFYRISVLTDKLVRLEYSQTGSFEDRTTQLIYNRDFGQ
                     VSLDYIETSNVLDIMTDYFHLHFNKGEFNAENLFIELKGNFAVYGSRWYFGESIETLK
                     GTARTLDKADGAISLEDGIISRNGIALLDDSQGFIWDEQSGYIERENQIDLYFFAYGH
                     DYRGAIRDFYHLTGSTPLLPRYALGNWWSRYWPYTSDEYLDLIDRFETEKIPLSIGVL
                     DMDWHITDIPARFGSGWTGYSWNRNLIPNPEQLLQQLHDRKLKLSLNVHPADGIRAYE
                     EAYPQIAKRLGLNVELEEPAIFDFFNPSFREAYFKDVHYELEKQGVDFWWIDWQQGTQ
                     GMLDPLWLLNHYHYQDSCKNAEGGLILSRYAGPGSHRYPVGFSGDTIISWNSLRFQPY
                     FTATASNIGYSWWSHDIGGHMLGDYDEELQTRWLQFGVFSPITRLHSSRSPFNSKEPW
                     FFSETTSKIMKKYLRLRHQMIPYLYTMNVKTHEEGAPLISPIYYFYPENDESYNVPNQ
                     YFFGTELMVAPIVEKMDLTFQSAKVDVWFPEGEWYDFFSEKKYTGGVKLSVYRDISTT
                     PVFAKSGAIIPLVGSEIGMGVDLPEVVDWYVFPGKQHFFEMLEDQNGQRYKTRLSIDW
                     EMGMVELALQGDSSIVPSNRKHRIHFKGTNVSIIELPNKNDTAKFEWKDNKRTSLNDE
                     VFRLLKTASLPYELKDRLLNQFINAKNSHDLMNILHHQDKELRGRLLEMIFTSQN"
     gene            complement(12242..12718)
                     /locus_tag="VQU30_000726"
     CDS             complement(12242..12718)
                     /locus_tag="VQU30_000726"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398949.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione peroxidase"
                     /protein_id="HET2446867.1"
                     /translation="MTSLYDFSVLNQNNQATPLDSYRGKVLLIVNTATGCGLTPQYQG
                     LQELYERYQDQGFEILDFPCNQFMGQAPGSAEEINAFCSLHFQTTFPRFAKIKVNGKE
                     ADPLYVWLKDQKSGPLGKRIEWNFAKFLIGRDGQVFERFSSKTDPKQIEEAIQTLL"
     gene            12941..16141
                     /locus_tag="VQU30_000727"
     CDS             12941..16141
                     /locus_tag="VQU30_000727"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001193686.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG-anchored hyaluronate lyase"
                     /protein_id="HET2446868.1"
                     /translation="MQTKTKKLIVSLSSLVLSGFLLNHYMTVGAEETTTNTIQQSQKE
                     VQYQQRDTKNLVENGDFGQTEDGSSPWTGSKAQGWSAWVDQKNSADASTRVIEAKDGA
                     ITISSHEKLRAAVHRMVPIEAKKKYKLRFKIKTDHKVGIAKVRIIEESDKDKRLWNSA
                     TTSGTKDWQTIEADYSPTLDVDKIKLELFYETGTGTVSFKDIELVEVADQPSEDYQTD
                     KQLEEKIDLPIGKKHVFSLADYTYKVENPDVASVKNGILEPLKEGTTNVIVSKDGKEV
                     KKIPLKILASVKDAYTDRLDDWNGIIAGNQYYDSKNEQMAKLNQELEGKVADSLSSIS
                     SQADRTYLWEKFSNYKMSANLTATYRKLEEMAKQVTNPSSRYYQDETVVRTVRDSMEW
                     MHKHVYNSEKSIVGNWWDYEIGTPRAINNTLSLMKEYFSDEEIKKYTDVIEKFVPDPE
                     HFRKTTDNPFKALGGNLVDMGRVKVIAGLLRKDDQEISSTIRSIEQVFKLVDQGEGFY
                     QDGSYIDHTNVAYTGAYGNVLIDGLSQLLPVIQKTKNPIDKDKMQTMYHWIDKSFAPL
                     LVNGELMDMSRGRSISRANSEGHVAAVEVLRGIHRIADMSEGETKQRLQSLVKTIVQS
                     DSYYDVFKNLKTYKDISLMQSLLSDAGVASVPRTSYLSAFNKMDKTAMYNAEKGFGFG
                     LSLFSSRTLNYEHMNKENKRGWYTSDGMFYLYNGDLSHYSDGYWPTVNPYKMPGTTET
                     DAKRADSDTGKVLPSAFVGTSKLDDANATATMDFTNWNQTLTAHKSWFMLKDKIAFLG
                     SNIQNTSTDTAATTIDQRKLESSNPYKVYVNDKEASLTEQEKDYPETQSVFLESSDSK
                     KNIGYFFFKKSSISMSKALQKGAWKDINEGQSDKEVENEFLTISQAHKQNGDSYGYML
                     IPNVGRATFNQMIKELERSLIENNETLQSVYDAKQGVWGIVKYDDSVSTISNQFQVLK
                     RGVYTIRKEGDEYKIAYYNPETQESAPDQEVFKKLEQAAQPQVQNSKEKEKSEEEKNH
                     SDQKNLPQTGEGQSILASLGFLLLGAFYLFRRGKNN"
     gene            16521..16906
                     /gene="tnpA"
                     /locus_tag="VQU30_000728"
                     /pseudo
     CDS             16521..16906
                     /gene="tnpA"
                     /locus_tag="VQU30_000728"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005816675.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS200/IS605 family transposase"
     gene            complement(17285..17914)
                     /locus_tag="VQU30_000729"
     CDS             complement(17285..17914)
                     /locus_tag="VQU30_000729"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000167291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional 4-hydroxy-2-oxoglutarate
                     aldolase/2-dehydro-3-deoxy-phosphogluconate aldolase"
                     /protein_id="HET2446869.1"
                     /translation="MTKSDTIIELKKQKIVAVIRGNTKEEGLQASIACIKGGIKAIEI
                     AYTNQYAGQIIKELVDLYQDDQSVCIGAGTVLDAVTARDAILAGANYVVSPSFHAETA
                     KMCNLYSTPYIPGCITLTEITTALEAGSEIIKLFPGSTLSPAYISAVKAPIPQVSVMV
                     TGGVGLNNIPQWFAAGADAVGIGGELNKLASQGNFDRISEIAQQYITLR"
     gene            complement(17924..18925)
                     /locus_tag="VQU30_000730"
     CDS             complement(17924..18925)
                     /locus_tag="VQU30_000730"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730651.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar kinase"
                     /protein_id="HET2446870.1"
                     /translation="MTKILLFGEPLIRISPLDATSIGDHVASSTYFGGSEINIACNLQ
                     ALGISTKVFTALPANEIGDRFLTFLKQHQIDTSSICRLGDRIGLYYLENGFGCRQSEV
                     FYDRKHTSISQIRPNMLDMDSLFQGISHFHFSGITIAIGQEVRAILLLLLEEAKRRGI
                     VVSMDLNLRTKMISVLEAKYEFSKFARFTDYCFGIDPLMIDDQNLEMFPRDSASLEEV
                     ENRMRLLKEAYGFKAIFHTLRSSDEQDKNVYQAYALEERFEESVQLKTAVYQRIGSGD
                     AFISGALYQLLHHSSLKTTIDFAVASATLKCTLPGDHLSTSATSIENLLANAQDIIR"
     gene            complement(18956..19597)
                     /locus_tag="VQU30_000731"
     CDS             complement(18956..19597)
                     /locus_tag="VQU30_000731"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398398.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RpiB/LacA/LacB family sugar-phosphate isomerase"
                     /protein_id="HET2446871.1"
                     /translation="MKIALINENSQASKNHIIYDSLKEATDKKDYQLFNYGMRGEEGE
                     SQLTYVQNGLMAAILLNTKAVDFVVTGCGTGVGAMLALNSFPGVVCGLAVDPTDAYLY
                     SQINGGNALSIPYAKGFGWGAELTLKLMFERLFAEEMGGGYPRERVIPEQRNARILNE
                     VKQITHNDLMTILKTIDQDFLKDTISGKYFQEYFFENCQDDEVAAYLKEVLAK"
     gene            complement(19616..20431)
                     /locus_tag="VQU30_000732"
     CDS             complement(19616..20431)
                     /locus_tag="VQU30_000732"
                     /EC_number="1.1.1.69"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000185867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gluconate 5-dehydrogenase"
                     /protein_id="HET2446872.1"
                     /translation="MTNTSFSIEQFSLKGKIALITGASYGIGFAIAKSYAEAGATIVF
                     NDINQDLVNKGIEAYREVGIEAHGYVCDVTDEDGIQAMVKQIEQEVGVIDILVNNAGI
                     IRRVPMCEMSAADFRKVIDIDLNAPFIVSKAVIPSMIKKGHGKIINICSMMSELGRET
                     VSAYAAAKGGLKMLTRNIASEYGGANIQCNGIGPGYIATPQTAPLRELQEDGSRHPFD
                     QFIIAKTPAARWGNPEDLMGPAVFLASDASNFVNGHILYVDGGILAYIGKQPE"
     gene            20702..21130
                     /locus_tag="VQU30_000733"
     CDS             20702..21130
                     /locus_tag="VQU30_000733"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000706826.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HET2446873.1"
                     /translation="MKIVLVGHGHFATGIYSSLQLIAGNQENVEAIDFVEGMSADELK
                     QKILLAISNEEEVLILSDLLGGSPFKVSSTIMGENPVKTMNVLSGLNLAMLMEAVFAR
                     MAHSFDEVVNKSVVAAQGGVVNGKELFSTDAEEEDFESGI"
     gene            21142..22332
                     /locus_tag="VQU30_000734"
     CDS             21142..22332
                     /locus_tag="VQU30_000734"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003074342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 88 protein"
                     /protein_id="HET2446874.1"
                     /translation="MIKKVTIEKIKSPERFLEVPLLTKEEVGQAIDKVIRQLELNLDY
                     FKEDFPTPATFDNVYPIMDNTEWTNGFWTGELWLAYEYSQQDAFKNIAHKNVLSFLDR
                     VNKRVELDHHDLGFLYTPSCMAEYKINGDGEAREATLKAADKLIERYQEKGGFIQAWG
                     DLGKKEHYRLIIDCLLNIQLLFFAYQETGDQKYYDIAESHFYASANNVIRDDASSFHT
                     FYFDPETGQPFKGVTRQGYSDDSCWARGQSWGVYGIPLTYRHLKDESCFDLFKGVTNY
                     FLNRLPKDHVSYWDLIFNDGSAQSRDSSATAIAVCGIHEMLKHLPEVDADKDIYKHAM
                     HAMLRSLIEHYANDQFTPGGTSLLHGVYSWHSGKGVDEGNIWGDYYYLEALIRFYKDW
                     NLYW"
     gene            22343..22834
                     /locus_tag="VQU30_000735"
     CDS             22343..22834
                     /locus_tag="VQU30_000735"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000178618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system
                     mannose/fructose/N-acetylgalactosamine-transporter subunit
                     IIB"
                     /protein_id="HET2446875.1"
                     /translation="MTMPNIIMTRIDERLIHGQGQLWVKYLACNTVIVANDEVSTDKM
                     QQTLMKTVVPDSVAMRFFPLQKVIDIIHKANPAQTIFIVVKDVKDALTLVEGGVPIKE
                     INIGNIHNAPGKEQVTRSIFLGEEDKAALKELSQTHQVTFNTKTTPTGNDGAVQVNIM
                     DYI"
     gene            22849..23628
                     /locus_tag="VQU30_000736"
     CDS             22849..23628
                     /locus_tag="VQU30_000736"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000026606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS
                     mannose/fructose/sorbose/N-acetylgalactosamine transporter
                     subunit IIC"
                     /protein_id="HET2446876.1"
                     /translation="MSINVFQAILIGLWTAFCFSGMLLGIYTNRCIVLSFGVGIILGD
                     LPTALAMGAIGELAYMGFGVGAGGTVPPNPIGPGIFGTLMAITSAGKVSPEAALALST
                     PIAVAIQFLQTFAYTVRAGAPETAMKHLKNHNLKKFKFTLNATIWLFAFIGFTLGCLG
                     ALSMDTLLKLVDYIPPVLLTGLTVAGKMLPAIGFAMILSVMAKKELIPFVLLGYVCAA
                     YLNIPTIGIAIVGTIFALIEFYNKPKTANHVVEEEAHDDWI"
     gene            23615..24433
                     /locus_tag="VQU30_000737"
     CDS             23615..24433
                     /locus_tag="VQU30_000737"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000148012.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose/fructose/sorbose transporter family
                     subunit IID"
                     /protein_id="HET2446877.1"
                     /translation="MTGSNKLTKRDYLKTSLRAFFCQNGFNYSNYQGLGYANVMYPAL
                     KKHYGEDQEGFYQALEENCEFYNTNPHFLPFITSLHLVMLENGRPAKETRSIKMALMG
                     PLAGIGDSLSQFCLAPLFSTIAASFAQEGLVVGPILFFLAMNTILTAIKLSTGLYGYK
                     LGTTVIDKLSEQMATISRIANIIGVTVIAGLAATSVKIMVPITFAAGEVKADAKQSIV
                     SIQGMLDKVAPALLPALFTLLVYYLIKEKKWTTYKLVILTVVIGIIGSWLKIIA"
     gene            24433..24726
                     /locus_tag="VQU30_000738"
     CDS             24433..24726
                     /locus_tag="VQU30_000738"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000381741.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit YajC"
                     /protein_id="HET2446878.1"
                     /translation="MDTTLFYGIVIVLAVSPLLLSSFHSIRQQKLLRKQTEQRQEYLA
                     SLTSGDEVLLLSGIHGKIISIKDDLVSLQIAKGVVIYVEKESVMGKTKELLFK"
     gene            24748..26649
                     /locus_tag="VQU30_000739"
     CDS             24748..26649
                     /locus_tag="VQU30_000739"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000657070.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alginate lyase family protein"
                     /protein_id="HET2446879.1"
                     /translation="MKEERRQFFERVDGNQCRDYILSHCSKDYEKVKSSLERLMDNRF
                     MFDSPWDMEPCSKIHQIQPMVWDQVFEDDPEWAYMLNRQEYLLQFMIGYVVEGDKDYI
                     QKCKFFLFDWIEQVREFSPQSLMTRTLDTGIRSFTWLKLLLLLLKFDMLEEKELEKIL
                     VSLEKQIDFMKSYYRAKYTLSNWGILQTIPMLAIYYFFSDKMDLEEAYHFASEELKQQ
                     IETQILGDGSQFEQSILYHVEVYKALLDLCLLLPDLQDSYRELLEKMATYIQMMTGLD
                     GRTLAFGDSDSTETTEILSLSAVVLNKEDLLNGLDVKVDLLSLLFLGREKVKRLQEFE
                     KRAWQPKSMIFEDSGHVCIKDEHRYLFFKNGPLGSAHSHSDENSFCLQYQGQPIFIDA
                     GRYSYREIYERYLLKSAWSHSTCIVDGKAPERITGSWEYEYYPHSLFCHHKEREGVHY
                     IEGAYWSAEPDLPYLHKRKILMLVEDVWLLVDDIRCQGQHEALTQFILDKDVTYQDGK
                     INQLRLWSEVDFDLEDTIISPKYNELERSNKLTKRQFFENQMLDYTIIAHESFEIIRH
                     SVYQTDDREVENALAFEVKNDETDKLILLLSEDICVGEKLCLVDGTKMRGKCLVYDKI
                     NERMIRLQC"
     gene            26709..27710
                     /locus_tag="VQU30_000740"
     CDS             26709..27710
                     /locus_tag="VQU30_000740"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000412458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HET2446880.1"
                     /translation="MEKKLTIKDIAEMAQTSKTTVSFYLNGKYEKMSQETREKIEKVI
                     HETNYKPSIVARSLNSKRTKLIGVLIGDITNSFSNQIVKGIEDIASQNGYQVMIGNSN
                     YSQESEDRYIESMLLLGVDGFIIQPTSNFRKYSRIIDEKKKKMVFFDSQLYEHRTSWV
                     KTNNYDAVYDMTQSCIEKGYEHFLLITADTSRLSTRIERASGFVDALTDANMRHASLT
                     IEDKHTNLEQIKEFLQKEIDPDEKTLVFIPNCWALPLVFTVIKELNYNLPQVGLIGFD
                     NTEWTCFSSPSVSTLVQPSFEEGQQATKILIDQIEGRNQEERQQVLDCSVNWKESTF"
     gene            complement(27820..28155)
                     /locus_tag="VQU30_000741"
     CDS             complement(27820..28155)
                     /locus_tag="VQU30_000741"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000838135.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2446881.1"
                     /translation="MKSLARLLNIHVFISIFLFFALISGAVSHTVLLLLLLFLPALNK
                     GLEKIQSKRIPVLNAALFFLLISFPQLLTNPVQWKFSIFLVVTIISSLAYFYNFYQVV
                     KEVDQKQLI"
     gene            complement(28166..28408)
                     /locus_tag="VQU30_000742"
     CDS             complement(28166..28408)
                     /locus_tag="VQU30_000742"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000711734.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2446882.1"
                     /translation="MKKEKKQLRYPGLKAGSIYGTVIFFIIPLIDTLTSENPNFISSL
                     LNTKHIFKTILGAFFFGVMIHIVDSLRIARAKKDQD"
     gene            complement(28419..28961)
                     /locus_tag="VQU30_000743"
     CDS             complement(28419..28961)
                     /locus_tag="VQU30_000743"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000712356.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3278 domain-containing protein"
                     /protein_id="HET2446883.1"
                     /translation="MKKETFTEKLIKRTYGISGPLDEYKRREADSIGNQVFIVLFYLM
                     IFGNLIPLLLAYKYPQEVALIYPPLILVIALIAAGYVTYQMKKTGITVIEPDMLNEKE
                     SKQLHYPGLKAGLFFGLWMFFITPLLSILIDEGQDYFHSLLTIRNGVSSILGSIFFGA
                     SIQFLISRRIAKTKKNQDED"
     gene            complement(28977..29171)
                     /locus_tag="VQU30_000744"
     CDS             complement(28977..29171)
                     /locus_tag="VQU30_000744"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001082472.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HET2446884.1"
                     /translation="MNRVKEFRKELGISQLELAKDIGVSRQTINMIENDKYNPTLELC
                     LNLARSLQTDLNSLFWEEDF"
     gene            29337..30287
                     /gene="rsmH"
                     /locus_tag="VQU30_000745"
     CDS             29337..30287
                     /gene="rsmH"
                     /locus_tag="VQU30_000745"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466808.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (cytosine(1402)-N(4))-methyltransferase
                     RsmH"
                     /protein_id="HET2446885.1"
                     /translation="MTKEFHHVTVLLHETIDMLDVKPDGIYVDATLGGAGHSEYLLSK
                     LSEKGHLYAFDQDQNAIDNAQKRLAPYIEKGMVTFIKDNFRHLQARLREAGVQEIDGI
                     CYDLGVSSPQLDQRERGFSYKKDAPLDMRMNQDASLTAYEVVNHYDYHDLVRIFFKYG
                     EDKFSKQIARKIEQAREVKPIETTTELAEIIKLVKPAKELKKKGHPAKQIFQAIRIEV
                     NDELGAADESIQQAMDMLALDGRISVITFHSLEDRLTKQLFKEASTVEVPKGLPFIPD
                     DLKPKMELVSRKPILPSAEELEANNRSHSAKLRVARKIHK"
     gene            30299..30616
                     /gene="ftsL"
                     /locus_tag="VQU30_000746"
     CDS             30299..30616
                     /gene="ftsL"
                     /locus_tag="VQU30_000746"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000840841.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsL"
                     /protein_id="HET2446886.1"
                     /translation="MAEKMEKTGQILQMQLKRFSRVEKAFYFSIAVTTLIVAISIIFM
                     QTKLLQVQNDLTKINAQIEEKKTELDDAKQEVNELLRAERLKEIANSHDLQLNNENIR
                     IAE"
     gene            30620..32872
                     /gene="pbpX"
                     /locus_tag="VQU30_000747"
     CDS             30620..32872
                     /gene="pbpX"
                     /locus_tag="VQU30_000747"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000872287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein 2X"
                     /protein_id="HET2446887.1"
                     /translation="MKWTKRVIRYATKNRKSPAENRRRVGKSLSLLSVFVFAIFLVNF
                     AVIIGTGTRFGTDLAKEAKKVHQTTRTVPAKRGTIYDRNGVPIAEDATSYNVYAVIDE
                     NYKSATGKILYVEKTQFNKVAEVFHKYLDMEESYVREQLSQPNLKQVSFGAKGNGITY
                     ANMMSIKKELEAAEVKGIDFTTSPNRSYPNGQFASSFIGLAQLHENEDGSKSLLGTSG
                     MESSLNSILAGTDGIITYEKDRLGNIVPGTEQVSQRTMDGKDVYTTISSPLQSFMETQ
                     MDSFQEKVKGKYMTATLVSAKTGEILATTQRPTFDADTKEGITEDFVWRDILYQSNYE
                     PGSTMKVMMLAAAIDNNTFPGGEVFNSSELKIADATIRDWDVNEGLTGGRMMTFSQGF
                     AHSSNVGMTLLEQKMGDATWLDYLNRFKFGVPTRFGLTDEYAGQLPADNIVNIAQSSF
                     GQGISVTQTQMIRAFTAIANDGVMLEPKFISAVYDPNDQTARKSQKEIVGNPVSKDAA
                     SLTRTNMVLVGTDPVYGTMYNHSTGKPTVTVPGQNVALKSGTAQIADEKNGGYLVGLT
                     DYIFSAVSMSPAENPDFILYVTVQQPEHYSGIQLGEFANPILERASAMKDSLNLQTTA
                     KALEQVSQQSPYPMPSVKDISPGDLAEELRRNLVQPIVVGTGTKIKNSSAEEGKNLAP
                     NQQVLILSDKVEEVPDMYGWTKETAETLAKWLNIELEFQGSGSTVQKQDVRANTAIKD
                     IKKITLTLGD"
     gene            32874..33854
                     /locus_tag="VQU30_000748"
     CDS             32874..33854
                     /locus_tag="VQU30_000748"
                     /EC_number="2.7.8.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000470804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phospho-N-acetylmuramoyl-pentapeptide-
                     transferase"
                     /protein_id="HET2446888.1"
                     /translation="MFISISAGIVTFLLTLVGIPAFIQFYRKAQITGQQMHEDVKQHQ
                     AKAGTPTMGGLVFLITSVLVAFFFALFSSQFSNNMGMILFILVLYGLVGFLDDFLKVF
                     RKINEGLNPKQKLALQLLGGVIFYLFYERGGDMLSVFGYQVHLGIFYIVFALFWLVGF
                     SNAVNLTDGVDGLASISVVISLSAYGVIAYVQGQMDILLVILAMIGGLLSFFIFNHKP
                     AKVFMGDVGSLALGGMLAAISMALHQEWTLLIIGIVYVFETTSVMMQVSYFKLTGGKR
                     IFRMTPVHHHFELGGLSGKGNPWSEWKVDFFFWGVGLLASLLTLAILYLM"
     gene            34463..36568
                     /locus_tag="VQU30_000749"
     CDS             34463..36568
                     /locus_tag="VQU30_000749"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001063457.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit"
                     /protein_id="HET2446889.1"
                     /translation="MNNNFNNFNNMDDLFNQLMGGMRGYSSENRRYLINGREVTPEEF
                     AHYRATGQLPGNAETDVQMPQQASGMKQDGVLAKLGRNLTAEAREGKLDPVIGRNKEI
                     QETSEILSRRTKNNPVLVGDAGVGKTAVVEGLAQAIVNGDVPAAIKNKEIISIDISGL
                     EAGTQYRGSFEENVQNLVNEVKEAGNIILFFDEIHQILGAGSTGGDSGSKGLADILKP
                     ALSRGELTVIGATTQDEYRNTILKNAALARRFNEVKVNAPSAENTFKILQGIRDLYQQ
                     HHNVILPDEVLKAAVDYSVQYIPQRSLPDKAIDLVDVTAAHLAAQHPVTDVHAVEREI
                     ETEKDKQEKAVEAEDFEAALNYKTRIAELERKIENHTEDMKVTASVNDVAESVERMTG
                     IPVSQMGASDIERLKDMAHRLQEKVIGQDKAVEVVARAIRRNRAGFDEGNRPIGSFLF
                     VGSTGVGKTELAKQLALDMFGTQDAIIRLDMSEYSDRTAVSKLIGTTAGYVGYDDNSN
                     TLTERVRRNPYSIILLDEIEKADPQVITLLLQVLDDGRLTDGQGNTVNFKNTVVIATS
                     NAGFGYEANLTEDADKPELMDRLKPFFRPEFLNRFNAVIEFSHLTKEDLSKIVDLMLA
                     EVNQTLAKKDIDLVVSQAAKDYITEEGYDEVMGVRPLRRVVEQEIRDKVTDFHLDHLD
                     AKHLEADMEDGVLVIREKA"
     gene            37291..38310
                     /locus_tag="VQU30_000750"
     CDS             37291..38310
                     /locus_tag="VQU30_000750"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001818716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lantibiotic biosynthesis protein"
                     /protein_id="HET2446890.1"
                     /translation="MSNTLKQLLLFREEFIKNILNGIDVDETVVIENDFVEELENFLK
                     ENDLLDFSNSIFFQLSGDKVIVNNIYPGYLAYFNRFLTFYPKIFAIKEVGEYIDFLNF
                     EKRIADMFYCWGFNANSRVLTAEKIIEIPNHQINAKYIKKVIKMSELLFGVDSNNRIR
                     LLNNRRELIKTIFQGSVIKSAIPALAATLDTISNSGSFQISLSKQIINNLVLSGKDKV
                     TIPRIELDNVVLSRQKIIVSVSYINDFLDLRFPDKIEYILNFLEGSGFNTKVMVYFGK
                     IVEEDKNYFVNLEKPQYFDFTSILFNKLFFKELNKFDYMVIEELIPNLDEDVMMTEYI
                     KEYTE"
     gene            38323..>38639
                     /locus_tag="VQU30_000751"
     CDS             38323..>38639
                     /locus_tag="VQU30_000751"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000603792.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2446891.1"
                     /translation="MILSKVRCYIYNSKIRGKVLYELYEFINENKQLMDAINSIKVDS
                     SNGFSIQILHLGEQQTTVLLTDFFTKTLDLFKEFRVTNKSTLEQVKNQISILNSSGPK
                     MDLT"
BASE COUNT        12300 a         6338 c         8241 g        11760 t
ORIGIN      
        1 agttactttg agaagttacc gaaaaatatt tttcatatct attgactttt aggggtgaaa
       61 tttggtatga tagtaggcgg tattgtttac cccatttgaa aggccccgga accttccaaa
      121 tacttttcga tgggaaggaa cacccatcac cgtaaacaaa aatcgaacta tatataggag
      181 aaatcatgaa caaaacaaca tttatggcta aaccaggcca agttgaacgt aaatggtacg
      241 tagttgacgc aactgatgta ccacttggac gtctttctgc agtagttgct agcgtacttc
      301 gcggaaaaaa caaaccaaca tttacaccac acactgatac aggtgacttc gtgattgtta
      361 tcaatgctga aaaagttaaa ttgactggta aaaaagcaac tgataaaatc tactacactc
      421 actcaaacca cccaggtgga ttgaaacaaa tctctgcagg tgaacttcgt tctaaaaatg
      481 cagtacgttt gattgagaaa tcagttaaag gtatgcttcc acacaataca cttggacgcg
      541 ctcaaggtat gaagttgaaa gtatttgttg gagctgagca cactcatgct gcacaacaac
      601 cagaagttct tgacatttca ggacttatct aaggaaagga acaaataaag tatgtcacaa
      661 gcacaatatg caggtactgg acgtcgtaaa aacgctgttg cacgcgttcg ccttgttcca
      721 ggaactggta aaatcactgt taacaaaaaa gatgttgaag agtacatccc acatgctgac
      781 cttcgtcttg tcatcaacca accattcgca gttacttcaa ctgtaggttc atacgacgtt
      841 ttcgttaacg ttgtaggtgg tggatacgct ggtcaatcag gagctatccg tcacggtatc
      901 gctcgtgccc ttcttcaagt agacccagac ttccgcgatt cattgaaacg cgcaggactt
      961 cttacacgtg actcacgtaa agttgaacgt aagaaaccag gtcttaagaa agctcgtaaa
     1021 gcatcacaat ttagtaaacg ttaattcgaa agaattacta tacttataca gagcaccttt
     1081 cggggtgttc tttttttata ctttcttact aaattggtgc aattgacaca gttgttgcga
     1141 ctttagttgc ttacaaatgt ggctgcaacc tgacaaggtc agttgcctca aaacgctaat
     1201 caatacaatt atatcaatgt ttcaaagcac tcaaaggttt gccctatggg tgcttttttc
     1261 gtgttttttt gaaaagttta ccttattttt atagtaaggt gaaataagaa taggacaaac
     1321 cgaggatagt caaatcgaat tctaacaatg ttttagaagt agaggtgtac tattctagtt
     1381 tcaatctact atattatgga taatgcaaga ttccatagaa tgggtaagtt agaactcttg
     1441 tgtgaagagt ttgggtataa acttttacct cttcctccct actcacctga gtacaatcct
     1501 attgagaaaa catgggctca tatcaaaaag cacctcaaaa aggtattacc aagttgcaat
     1561 accttttatg aggctctttt gtcttgttct tgtttcaatt gactataaat cgctataaga
     1621 aaaaatcatt ttattggtat aaagaagtga ttgaaagtaa tggcgaaacg ttagataatt
     1681 agttcataaa aaacaagttt agatcctcat ctaaacttgt ttttttaaaa ttgaaggatg
     1741 attttggagg atatgagatg acattgacta ttcatgtata ttataaaggc gatggagatt
     1801 gtgcaataaa gtttgcaaga gaaatgcttg aatctgggct tgtcgcagaa attagatgtc
     1861 aaaaaggtaa tttgaaatac gaatattttt taccaattga aaaagaggga attattctcc
     1921 ttattgatca gtggataaat caagaagctt tagatgaaca tcatcaatca aatacaatgc
     1981 agaaaatctt agatttaaga aaaaaatatc acttgcagat gcaagttgaa cgttatatag
     2041 aagatgattc tgggatgcca gaaagcgata agtcgtttat agacacaggg aattagaatt
     2101 attgtgagag tttttgtagt ttgaaagtat tgaaaatcgt aaagatatca ttacgagaat
     2161 acaagaagat attgttctat ttccattaaa aattacttct ttccttaata ataaggaaaa
     2221 agaatacgtt ttcatctttt ggtttgaggt ttataataag aatatcaaag tcaggaggaa
     2281 aaaagatgac tacttttaaa gatggatttt tatggggtgg tgctgttgct gctcatcaac
     2341 ttgaaggcgg atggcaagaa ggtggcaaag gaattagtgt tgctgatgtt atgactgctg
     2401 gtcgccatgg agtagctcgt gaaattactt tgggagtttt agagggtaaa tattatccaa
     2461 atcatgaggc gatagatttt tatcatcgtt ataaagaaga catagcactt tttgctgaaa
     2521 tgggattcaa gtgcttccgt acctctattg catggacacg tatctttcca aaaggtgatg
     2581 agttagagcc gaatgaagaa ggattacagt tttatgataa tctttttgat gaatgcttaa
     2641 agaatggtat tgaacctgtc atcactctat ctcattttga aatgccttat cacttagtga
     2701 ccgaatatgg tggttggaaa aataggaaat tgattgattt ctttgctcgt tttgcagaag
     2761 tcgtatttaa acgttacaaa gataaggtta aatattggat gactttcaat gaaatcaata
     2821 atcaagcgaa ttatcaggaa gattttgcac catttactaa ctcaggtatt gtatatgagg
     2881 aaggtgataa tagagaagca attatgtatc aagcagcaca ttacgaatta gttgcttctg
     2941 cacgagctgt aaaaattggt catgagatta atccagattt tcaaataggt tgtatgattg
     3001 cgatgtgtcc aatttatcca gttacttgca atcctaagga tatcttaatg gcaatgaaag
     3061 ctatgcagaa gcgttattat tttgctgatg tgcatgtttt aggtaaatat cctgagcata
     3121 ttttcaagta ttgggaacga aaaggtattt cagttgattt tactgaccag gataaagaag
     3181 atttacttgg tgggactgta gattacattg gtttcagtta ctatatgtcc tttgctatag
     3241 actctcatcg tgaaaataat ccttattttg attatcttga aacagaagat ttagtgaaaa
     3301 ataattatgt taaggcttct gaatgggagt ggcaaattga tccagaaggt ttacgttatg
     3361 cgttaaattg gtttacagac cactatcact taccactctt tattgttgaa aatggttttg
     3421 gagctataga tcaagttgca gcagatggta tggtacatga tgattataga attgaatatc
     3481 taggtgccca tattcgtgaa atgaaaaagg ctgtagttga agatggtgtt gatttaatgg
     3541 gttatactcc atggggatgt attgatttgg tttcagctgg taccggtgaa atgcggaaac
     3601 gttatggctt tatttatgta gataaagatg acaatgggaa gggaagttat aatcgttccc
     3661 cgaaaaaatc ttttggctgg tataagaaag ttattttatc taacggtgaa tcagtagaat
     3721 agtataaaca aactgagatt attctcagtt tgtttagcat attgaggaga catatgattg
     3781 gaagtattgc agcaatttta acaacatttg catttttacc acaagttttt cgtgtagtta
     3841 agacaaagga cacaggatct attgctctag gtatgtatgt tatgcaagtt attggtattg
     3901 cattgtggct tgctcatggt attcgtatag gagacttgcc tttgatttta gcaaatagtg
     3961 tttcatttct actctcagga ataattttat tttataaatt gaagtataaa taattttttt
     4021 ccatatcatt taggaaaatg agggaattgt cattgaaaac gctttatttt ataataaaaa
     4081 tagataacaa ataagccaac ttagcacagc tttgattgga tttaagaaaa ggagaaaata
     4141 ttatggcaaa agctttaatt atttgtgcag caggaatgtc ttcatcactt atggcacaga
     4201 aaacaacaga gtttctaaaa ggaaaaggga aagatattgt agttgatgct attagtgcta
     4261 ctgaaggagg gaaagctatc gcagcagcag cttttgattt gtatcttgtc agtcctcaaa
     4321 caaaaatgta ctttaagcaa tttgaagagg ctggttctaa agcaggaaaa ccagttgtac
     4381 aaatacctcc tcaagcctat attcctattc caatgggaat tgaaaaaatg gctaatttga
     4441 ttcttgagaa tatttgatga acacatgaaa tgtcaataaa tatttaagtt aagataaatt
     4501 gttttgagtt tgatataaat tgatttaagt gtataatatg cttcaatata tgaaaacata
     4561 cgttttagga gggaatgaat gtgttaaaca ttaaagagaa agatatcctt caatttttaa
     4621 taaaaaataa ggaacgtttt gttacaagca aagaactggc agaatattta tcctgttcag
     4681 atagaactgt ccgtaatgta ctgaaattaa ttgagaagac aatgattatt caaggagtcc
     4741 ggttgatttc aaaacaaggt caagggtatc aaatattttt tgagaatcaa ggcgcttacc
     4801 aggagtttag acaaacttat gaactggaag aagactatac gaaaactgcg gtttcaaaag
     4861 gtgatgatcg tttagtattt atcttaaata aattattatt tgagcaagtt ccagttcttt
     4921 ttgatgattt agctgatgaa ctttacgtta gtcgttcaac attatctcat gatttcagaa
     4981 agatacgagt gatgttatca gagtataatt tgtccattga gagtagggcg aataaaggag
     5041 tttatgtctc aggcgaggaa cgtgataaac gacgttttat cataaattat ttcctagaga
     5101 atcaattttt taaaacaata cattgctatg taaaatttaa cttttttgct caaactgttc
     5161 cattagaaga atttgctaga attgttttgg atgaatgcca agaggccaac ctaaaactat
     5221 ctgattttgt actacagaat ttagtagttc acatagcatt gtctgtgatt cgtttaaaat
     5281 ccggatttga aataaaaaat atagactgtc agatgactga tgatgcaata gagagaaagg
     5341 ttgctcaaag aattctttct aaagtaagag aagtaacaaa tcaggaattt ccagttcagg
     5401 aaatagacta cattactttg catttgttag ctaagagtca acaatgtcaa aaaaatcaga
     5461 agaatatttc tgaagaagtt ttaaaaaaat ctttatttaa aacatttcag aatttaggat
     5521 tagatgatat gtataacttt tcttcagatt tccaactaat tgaaggattg ataactcatc
     5581 taatgacact acaagtacgt ttagaaagcc ggattacctt aaataaccct ttggtagatg
     5641 aaattaaaca gaattatagt gatatattct ttatgactag agaaattctt gcaaatatgg
     5701 acaagttctt ggagtggaca atatcagatg atgaagtagc atatgtaagt cttcactttt
     5761 tagctgctat ggaacgtagc aaagagagta ctaagtttaa tattcttgct atttgtgcaa
     5821 caggatttgg tgcagcccaa atgttaagaa atcgtttgga aacggagttt gggaagcgag
     5881 tagaagttgt tgatgtaata ggctattatg aattgaatca agaaaaactt aaaggaatag
     5941 attttatagt gtcagctgtt gatttatcaa atctatattt tcaaattcca gtttttaaag
     6001 ttagtgtgtt tcttaagagt gatgagatgg aaatgattag aaaagctatg gatcagatgc
     6061 aagtttctag ttatgtacaa tcatcaaaga ttaataaatt tgaaaacaac agctttagac
     6121 agtattttag taaagaaaat tttttaatat gtactgaatc agacaaggta aatttacttg
     6181 aaaagatggt tgagagttta tctgttggtg aatcaaatga gtttgaacaa tctttacttt
     6241 atggaattaa acagcgcgaa gaattaagtt cagttgtttt ttctgaaaaa attgcagttc
     6301 cgcatcctat tcagcccttt ggtacagagg gaaaggtttc ggttgcaatc tgtaaagatt
     6361 cgttactctg ggataatcaa agttcatatg tccagctagt atttcttcta tctccatcaa
     6421 tatatgggaa cgaaggtttg gcaactgtga ctaaaaagat agtctctctg acagagaatg
     6481 atgagttgca aaatcagcta atatcttgca ataactttga agattttatt agcatatttg
     6541 agaagataaa ataggaggtt catatgaatc aagaggaact gcaggttgca gcatttgaaa
     6601 ttatcctgca ttcgggaaat gcaaggtcag aaatacatga agcatttgca aaaatgagag
     6661 aaggtagttt tgatgatgca gaaagtaaat taaatcaatc aaatgagata attcttgaag
     6721 cgcatcatgc acaaaccaaa ctcttgcaag aatacgcaag tggagtggaa attaaaattg
     6781 aaattatcat ggtacatgct caagatcatt taatgaccac tatgacatta ttagaagtag
     6841 caaaggaaat gttagctctt tataagaaag ttaactaaat atgtgttgtt atataaggag
     6901 gaaatgatat ggataaaaaa gaacgacaaa agattgaaca acaacgtcga gagatggctc
     6961 taactaatac tttttttaat cgatatcttc ttctacgtta ttcaatagca ctcttctttt
     7021 ttgggaatat ttattggctt ttgaatcagt ttattaatcc ctcgcctatt attattttcc
     7081 ccattatgct catagtattt tctattttag caactgttga acaatttaaa ctctatggaa
     7141 ataggaaaga aaagttggga ataacactaa tgtttgttag aatacaaata cttatttcaa
     7201 taggattact tgttttaact tggacaagtt ggtttaagaa tctttttccg atttttgaaa
     7261 ataaccaagt agcacgttta tttgtttttg tagttcttct attaggttta gttctgagtt
     7321 tgttagacat tagaagaatt aaaaaaattt ataaacgaac agataaggct tatcaacaat
     7381 ttgtccaatt ggaaaagaac tcacttagtt tataatcctg atctagtata atttgtattt
     7441 gaaactagtc tttagaaagt aaaaattatt atgttttatt aaggaggtct atttatggat
     7501 caacaaaacg ggttgtttgg ttttcttgaa aaccatgtta tgggaccaat gggcaaactt
     7561 gctcagttta aagtagtgcg tgctatcacg gctgcaggta tggctgctgt accatttact
     7621 attgtaggat caatgttttt ggtattcagt attttgccac aagctttctc attttggcca
     7681 attgtggcag atattttctc tgcttcattt gataaattca catcacttta catggttgca
     7741 aactatgcga ctatgggttc tctatctctt tatttcgttc tatcacttgc atatgaattg
     7801 acaaaaattt atgcagagga agaagaactc aatatgaatc ctcttaatgg tgccttgctc
     7861 gccttgatgg cttttgtcat gacagtaccg caaatcattt ttgatggtgg aatgatgaag
     7921 actgtgacaa gtctaaaaga aggtgcagta attgcagatg gatgggcaat gggaaatgga
     7981 gtcgcacgtt ttgggacaac agggattttt accgcaatca ttatggcaat tgtgactgtt
     8041 cttatttatc gtatgtgtgt taaacataat tgggttatta aaatgcctga agctgttcca
     8101 gaaggagttt ctcgtggatt taccgctttg gttccgggat ttgttgttgc atttgttgtt
     8161 atctttatca acggtcttct tgtagcaatg ggaacagata tttttaaagt cattgcaatt
     8221 ccatttggtt ttgtatccaa tctgactaat tcgtggattg gtttaatgat tatttatcta
     8281 ttgactcaac tactttggat tgtaggtatc cacggtgcga acattgtttt tgcatttgtt
     8341 agtccaattg ctcttgctaa catggctgaa aatgctgctg gcgggcactt cgctgttgca
     8401 ggtgaatttt ctaatatgtt tgtaattgca ggtggttctg gtgcaacttt aggactatgt
     8461 ttatatattg cttttgcctc taaatctgaa cagcttaaag caataggacg agcatctgta
     8521 gttccagcct tatttaatat taatgaacca ttaatttttg gattacctat tatctataat
     8581 ccagccttgg ctataccatt tattttagca ccaatggtta ctgctactat ttattacgta
     8641 gcgaattctc taaactttat taagccaatt atcgcacagg ttccatggcc aactccagta
     8701 gggattggag ctttcttagg gacagcagat cttcgagctg tattagttgc tctagtatgt
     8761 gcatttgcag cattcttagt ctatcttcca ttcatccgtg tatatgatca aaaattggtg
     8821 aaagaagagc aaggtatcta ataagtaaaa aagtatactc gatgatagaa tccatatagt
     8881 ttaaataatg agtgttaata ttagcagtga agaggtcttt ttaagatatt cttctctgct
     8941 ttttcatatt ttttcgctat gtagggtatg aagcaaaata gaaagtagtt cgaatagttg
     9001 ataaacagga aactgctgtt atttaaaaaa aacaataaag taaagtatgt tatcgtagaa
     9061 tacgatacaa tagtaaaaaa gcaaaaagaa tgcgttttat atttgggttt gaggtttata
     9121 aaataggata agcgtgctga aaacttagat atgacaaaca aaataaaatt tttaaaagct
     9181 acatagaaac atggtataat gtatctaaag gaggtagcat atgtccttag atatagataa
     9241 agaaaagatg acaatcatgg gaatagcttt tgaaaacaga tccgttttta agagtgtttg
     9301 gtatgcttta agtacaaata tgattgaagg atggcgacct acggttagtg atgttgaaaa
     9361 attacgagat gaagctcttg ctctggggat gacttaatga agcgcaactg ttatgagtct
     9421 tatgactatg ttgatccgga taatttatat accgatccgg gttcttcagt tctaagaaat
     9481 aagcaggaag gaaaaaagca cgcgagcttg aatatcgtat gattgctagt aagagtttga
     9541 aattatttat caatcctatc ttagttaata gtttaaaagt agtttgtttc acaactgcat
     9601 aagcttagaa aagttgaaaa gtgataactc tttaataaac tcttggtttg ttaaaagata
     9661 ttttgtccac tacatttttt caattgacta ttatttgtca tagatataac agatagaaca
     9721 gatagaacat tgcattcaga ataatgaaaa acgcatcaaa aatggtgcgt tctgttttta
     9781 tgctaccata aaaggaggaa aacaaattga aaatttttaa gggagagttt tatcgaatct
     9841 ctgtattaac agacaagcta gtaaggttag aatactctca aactggaagt tttgaggata
     9901 gaacgacaca acttatctat aatagagatt ttggccaagt ttcgttagat tatatcgaga
     9961 catcaaacgt actagatatt atgacggact attttcatct gcactttaat aaaggagaat
    10021 ttaacgccga aaatttattt atagaattaa aaggaaattt tgccgtatat ggtagtcgct
    10081 ggtattttgg tgaatctatt gaaacgttaa aaggaacagc tcggactctg gataaggcag
    10141 atggagcaat ctcgttagaa gatggaatta ttagccgaaa tggtatagcc ttattggatg
    10201 attctcaagg atttatttgg gatgaacaat ctggttatat tgagagagaa aatcaaattg
    10261 acctgtattt ctttgcctat gggcatgatt atagaggagc aatcagagac ttttaccatt
    10321 tgactggttc aacacccttg ttgccaagat atgctttagg caattggtgg agtagatatt
    10381 ggccttatac gtcggatgaa tacttggatt taatagacag atttgaaaca gagaaaattc
    10441 cattatctat cggtgtgtta gatatggatt ggcatataac tgacattcca gctcgttttg
    10501 gaagtggctg gacaggatat agttggaata gaaacttaat accaaatcca gaacagttat
    10561 tgcaacaact tcatgataga aagttaaaac tctccttaaa tgtccatcct gctgatggga
    10621 tacgggctta tgaagaagct tatcctcaaa tcgcaaaacg gttggggtta aatgtagaac
    10681 tagaagaacc tgctattttt gattttttta atccctcttt tagggaagcc tactttaaag
    10741 atgttcatta tgagctagaa aagcagggag tagatttttg gtggattgac tggcaacaag
    10801 ggacacaagg tatgctagat ccactttggc ttttaaacca ttatcactat caggatagtt
    10861 gtaaaaatgc agaaggtggt ttgattttat caagatatgc aggtcctggt agtcaccgct
    10921 accctgttgg tttttcaggg gatactatta ttagttggaa ttccttaagg tttcaaccct
    10981 attttacagc gacagcatct aatatcggtt atagttggtg gagtcatgat atcggtggac
    11041 atatgttggg ggattatgac gaagagctac aaactagatg gctacagttt ggtgttttta
    11101 gtccgattac tcgattacat agttctagaa gtccttttaa tagtaaagaa ccttggttct
    11161 tttcagaaac aacatctaag attatgaaga aataccttcg tttgagacat cagatgattc
    11221 cctatctata taccatgaat gtaaagacac atgaggaagg tgccccatta atcagtccaa
    11281 tctattattt ctatccagag aatgatgaga gctataatgt tccaaaccaa tacttttttg
    11341 gaacagaact gatggtggct cccattgtag aaaagatgga tttgacattc caatctgcaa
    11401 aagtagatgt atggttccct gaaggtgaat ggtatgactt cttttcagag aaaaaataca
    11461 caggtggtgt gaagttaagt gtttataggg acatctcgac tacgcctgtg tttgcaaaaa
    11521 gtggtgcaat cattcccttg gttggttctg agataggtat gggtgttgat ttacctgagg
    11581 ttgtagattg gtatgtattc ccagggaaac aacatttttt tgaaatgctt gaagatcaaa
    11641 atggtcaaag atataaaaca agattatcaa tcgattggga aatgggaatg gtagagttag
    11701 cattacaagg agattctagt atcgttccaa gcaatagaaa acatagaatt cattttaaag
    11761 gaacgaatgt gtctataatt gaattgccaa ataagaatga tacagctaaa tttgaatgga
    11821 aagataataa aaggacatct ttaaatgacg aagtttttag actactaaag acagcttctc
    11881 ttccatatga attaaaagat agattgttaa atcaattcat caatgcgaaa aactctcatg
    11941 acttaatgaa tatcttgcat catcaggata aggaattgag agggcgtttg ttggaaatga
    12001 tatttactag ccaaaactaa ttgaaataat tagaaagtca tttgtttagt gtatatgaag
    12061 attctgtatg gtattcgtta tcactggtca cattgaaaat gtgaaataag cacctacaac
    12121 atagacttta caacacttca tgtttcatat catggggtgt ttttctattt aagtcaaagc
    12181 ccatcaaaaa atctcactat tcatcaggtt aaaggaaacc taatcatagt gagattgtga
    12241 attatagtag agtttgtatc gcctcttcaa tttgttttgg gtctgttttt gaagaaaagc
    12301 gttcaaagac ttgcccatct cgaccgatga gaaacttagc gaaattccat tcgattcgtt
    12361 ttcctagtgg gccggatttc tggtctttta accagacata gagagggtct gcttccttac
    12421 cgttgacctt aatcttggca aaacgtggga aggtggtttg aaaatgtagg ctacagaagg
    12481 cgttgatttc ctctgcgctg ccgggtgctt gtcccataaa ctgattgcaa gggaaatcca
    12541 atatttcgaa gccctgatct tgatagcgtt catagagttc ttgaagtccc tggtactggg
    12601 gcgttaaacc acatccagta gcagtgttga caatcaagag aactttgcca cgatagctat
    12661 ccaagggagt tgcttggttg ttttggttca aaacggaaaa atcataaagt gaagtcatga
    12721 gggcctcttt tctttttcta cattgtaaca gtttttactt ttttcgtcga gtcggatgga
    12781 agatattgtt gaagaataag ccttcaatat gatagaaacc gtttacaaat aactttaaaa
    12841 atggtatgat ttaattaaac cggtttactt agttgctata aatctctaat ttgagattta
    12901 gttcctattg attttacaat atgtttattg gagtgtatac atgcaaacaa aaacaaagaa
    12961 gctcattgtg agtttgtctt cacttgtttt atcaggattt ttattaaacc attatatgac
    13021 agttggagcg gaagaaacga ctacgaatac cattcagcaa agccagaagg aagttcagta
    13081 tcagcaaagg gatacaaaaa atttagttga aaatggtgat tttggtcaga cggaggacgg
    13141 aagcagtccg tggacaggaa gcaaagctca ggggtggtca gcttgggtag accagaagaa
    13201 tagtgcagat gcctcaactc gagtcattga ggctaaggat ggggctatca ctatctcaag
    13261 ccatgagaaa ttaagggcag cggttcaccg tatggttcct attgaagcta agaaaaagta
    13321 taaactgcgt ttcaagatta aaacagatca taaagtcggg attgccaaag ttcgtatcat
    13381 tgaggaaagt gataaggaca agcgattgtg gaattctgca acgacgtcag gaacaaagga
    13441 ctggcagacc attgaagcag actatagccc gactttagat gttgataaaa tcaagctgga
    13501 gttattctat gaaacaggaa ctgggactgt ttcctttaag gatattgagc tggtagaggt
    13561 agcagaccag ccttctgagg actatcaaac agataaacag cttgaggaaa agattgattt
    13621 accaattgga aaaaaacatg ttttttctct tgcggactat acttataagg tagaaaatcc
    13681 tgacgttgct tcagtcaaaa atggaatttt agaacctctt aaggaaggga caaccaatgt
    13741 cattgtcagt aaagatggca aggaagtgaa aaagattcct ttgaagattc tagcctctgt
    13801 taaggatgca tacacagacc gtttggatga ctggaatggc atcatcgctg ggaatcaata
    13861 ctatgattct aaaaatgaac agatggccaa attaaaccag gaattggaag gaaaggtagc
    13921 tgatagccta tctagtattt caagtcaggc ggaccgcacc tatttgtggg aaaaattttc
    13981 aaattataaa atgtctgcaa atctgactgc cacttatcgg aaattggagg agatggccaa
    14041 gcaagtgacc aatccttctt ctcgttatta tcaagatgaa actgtcgttc gaacagtcag
    14101 ggattccatg gaatggatgc ataaacatgt ctacaatagt gaaaagagca ttgttgggaa
    14161 ctggtgggat tatgaaatcg gtacacctcg tgccatcaac aataccttgt ctctgatgaa
    14221 agaatacttc tctgatgagg aaattaaaaa atatacagat gtgattgaaa aatttgtacc
    14281 agatcccgaa catttccgaa agacgactga taacccattt aaggctctag gtggaaactt
    14341 agttgatatg ggaagagtaa aagtaatagc tggtttactg cgtaaggatg atcaagaaat
    14401 ttcttctacc attcgctcga ttgagcaagt gttcaagttg gtagaccaag gtgaaggttt
    14461 ttatcaagat ggatcctata tcgaccatac caatgttgcc tatacgggtg cttatgggaa
    14521 tgttttgatt gatggcctgt ctcaactgtt gccagtcatt caaaagacca agaatccaat
    14581 cgataaagat aaaatgcaaa ccatgtacca ctggattgat aaatcgtttg ctcctttgct
    14641 ggtgaatgga gagctgatgg atatgagtcg tggacgctcg atcagtcgtg caaatagcga
    14701 ggggcacgtg gccgcagtag aagtactaag agggattcac cgaatagcgg atatgtctga
    14761 aggagaaacc aaacaacgtt tgcagagtct tgtgaagacc attgttcaat cggatagtta
    14821 ttatgatgtc tttaagaatt tgaagactta taaggatatc agtttgatgc aatccttgtt
    14881 aagtgatgca ggagtcgcaa gtgttccaag aacaagttac ctatctgcct ttaacaagat
    14941 ggataaaaca gccatgtaca atgcagagaa agggtttgga tttggcttgt cactcttttc
    15001 cagtcgtacc ttgaattacg aacacatgaa caaggaaaat aaacgtggtt ggtatacgag
    15061 tgatgggatg ttctatcttt acaatggcga tttgagtcac tatagcgatg gctactggcc
    15121 aacagttaat ccatataaga tgcctggtac aacagagacg gatgctaaga gagcggatag
    15181 cgatacaggt aaagttttac cgtctgcttt cgttggaacg agcaaactag atgatgccaa
    15241 tgcgacagca accatggatt tcaccaactg gaatcaaaca ttgactgctc ataagagctg
    15301 gtttatgcta aaggataaga tcgccttttt aggaagcaat atccaaaaca cttcaacaga
    15361 tactgctgca actacaattg accagagaaa actggaatca agtaatccat ataaagtcta
    15421 tgtcaatgat aaagaagcct cccttacaga acaagaaaag gattatcctg aaacccaaag
    15481 tgtcttttta gaatcatccg attcgaaaaa gaatattggt tactttttct ttaagaagag
    15541 ttcaatcagt atgagtaagg ctttgcaaaa gggagcctgg aaggatatca atgaaggaca
    15601 gtcagacaag gaagttgaaa atgaatttct tacgattagt caggctcata agcaaaatgg
    15661 agattcttat ggctatatgc tcatccctaa cgtgggtcgt gccaccttca atcaaatgat
    15721 aaaagagtta gaaagaagcc tcatcgaaaa taacgaaacc cttcagtctg tttatgatgc
    15781 caaacaagga gtttggggca ttgtgaaata tgatgattct gtctctacta tttccaacca
    15841 attccaagtt ttgaaacgtg gagtctatac cattcgaaaa gaaggggatg aatataagat
    15901 tgcctactat aatcctgaaa cccaggaatc agctccagat caggaagtct ttaaaaagct
    15961 agagcaagca gctcagccac aagtacagaa ttcaaaagaa aaggaaaaat ctgaagagga
    16021 aaagaaccat tcggatcaaa agaatctccc tcagacagga gaaggtcagt caatcttggc
    16081 aagtctaggg ttcttgctac ttggggcgtt ttatttattc cgtagaggaa agaacaacta
    16141 atttgttcat catctagatg aattacatga aactgtggaa aatagaaaaa atccgaagaa
    16201 ggccaaatat cttcggattt ttcttttaaa aaaggataag ttgatactta tcctttttac
    16261 ttcattatgt gactatagcg ttttgaaact agaataggac atcataactg ctaaaagatt
    16321 tctataaatt catttgattt tcctaatcaa tttattcgta tcctatttca ctctactata
    16381 ttagtccgtc tcgcacctca cggagcgaga caaaacaacc acccgctatg cgggtgcgcg
    16441 tcgaaggtta taccaaaaaa actccaaacg cgatacaata aaggtgttca atccacttgt
    16501 aaagcgaaag gagaaaaaat atggcacaaa aggctcatag tttatctcac acaaagtgga
    16561 ggtgttctat cacattgtgt tcacccctaa gtatagacga aaagtcatct ataatcaata
    16621 tagaagtagt ttaggcgaaa tatttcatcg cttgtgtagt tataaaggtg ttgaaatgat
    16681 cgagggtcac ttaatgccag accatgtaca catgttagtc agtattccac taaggctaag
    16741 tgtttcgagt ttcatgggtt atttaaaagg aaaaagtgca ctcatgatgt ttgacaaaca
    16801 cgccaatctc aagtacaagt ttgggaatcg gcatttctgg gtggaaggtt attatgtaag
    16861 tccagtaggg cttaatgaag ccacaattaa gaaatatagt caagattaaa gaaattatcc
    16921 agtggatgat ttcttcacga gtatgaaaat ttgagaacta gtaaagtatg atatatagta
    16981 aaatgaaata agaacaggac aaaatcgatc aggacagtca aatcgatttt taacaatgtt
    17041 ttagaagtag aggtatacta ttccagtttc aatctactat agcactagat aaattgagtg
    17101 taaaagaata tgaggatccc tttagggata gtggtaagta ataccaaagt ctcttaaaga
    17161 ggcaagtgac gagtcaagag caataaggct tgaacaacgt aaaagccagc gtctttaggc
    17221 gctggctgat gatttgggct tatagctctg ggataaacca cccgttagac gggtagttat
    17281 gattttatct gagtgtaata tactgttggg caatctcgct gatgcggtca aagttgcctt
    17341 gggaagcgag tttattgagt tcgccaccaa ttccaacggc atctgcacca gcagcgaacc
    17401 attgagggat gttgtttagg ccgactcctc cggttaccat tacggaaact tgtgggatcg
    17461 gtgccttgac tgcagagata tatgctggac tgagagtact acctgggaag agtttgatga
    17521 tttcactacc ggcttcaagt gcagtcgtga tctctgtgag ggtaatacag cctggaatgt
    17581 acggtgtgct gtagagattg cacattttcg cagtttcagc atggaaagat ggagaaacaa
    17641 cgtaatttgc tccagctaga atggcatctc tagcagttac ggcatcaagc acagtacctg
    17701 caccgataca aacactctga tcgtcctgat acaagtctac aagttccttg atgatttgtc
    17761 ctgcatactg attggtatag gcgatttcaa tagctttgat accgcccttg atacaagcaa
    17821 tcgaggcttg tagtccttct tcctttgtat ttcctcgaat gacagcgaca attttctgtt
    17881 tttttagttc aataatcgta tctgatttgg tcatgtaatt ctcctaacga atgatatctt
    17941 gtgcatttgc cagtaaattt tcaatactag ttgcggaagt ggagagatgg tctcctggaa
    18001 gagtgcattt gagagttgcg ctcgcaactg caaagtcaat ggtagttttt agggaggaat
    18061 gatggagtag ttggtaaagg gcaccagata taaaggcatc cccgctacca attcgttgat
    18121 agactgcagt ttttagttgg acagactctt caaatcgttc ttccagagca taggcttgat
    18181 agacattttt gtcttgctca tcactagatc ggagggtatg gaaaatggcc ttgaaaccat
    18241 aggcttcttt taaaagtcgc atgcgatttt ccacctcttc taggctagca ctgtctcttg
    18301 gaaacatctc tagattttgg tcatcaatca tgagaggatc aataccgaag caatagtcag
    18361 taaaacgtgc aaacttagaa aattcatact tggcttctag gactgaaatc atctttgttc
    18421 tcagattgag atccattgaa acgacaattc ctcggcgctt ggcttcttcc aagagtagga
    18481 gaaggatcgc acggacctct tgaccgatag ctatggtgat tccactaaaa tgaaaatggc
    18541 taatcccctg aaagagagaa tccatatcta gcatgtttgg ccgaatctgg ctgatactcg
    18601 tatgcttacg atcgtagaaa acttcacttt gacgacaacc aaagccgttc tccaaatagt
    18661 agaggccgat tcgatcgcca agccgacaga ttgaactggt atcgatttgg tgctgtttca
    18721 agaatgtgag aaaacgatct ccaatctcgt tggcagggag tgcggtaaag actttcgttg
    18781 agatacccag ggcttgcaaa ttacaagcga tgttaatttc tgatccgcca aaataagtcg
    18841 aactggcaac atgatcgccg atactggtgg catctaatgg tgagattcga attaatggtt
    18901 cgccaaacag taatattttc gtcatccatt agttcctttc tggtttagaa tagctttact
    18961 tggctaatac ttctttcaaa taagcagcga cttcatcatc ttggcagttt tcaaagaagt
    19021 attcttggaa gtatttgcca gagatggtgt ctttgaggaa gtcttggtcg attgttttaa
    19081 ggatggtcat caaatcattg tgggtgattt gtttcacctc gtttaagata cgagcgttgc
    19141 gttgttcagg gattacacgt tctcttgggt agccaccgcc catttcttca gcaaataagc
    19201 gttcaaacat caatttgagg gtcagttctg ccccccagcc aaatcctttg gcataaggga
    19261 tagacaaggc gttaccacca ttgatttgag aataaaggta agcgtcagtt gggtccactg
    19321 ctagaccaca gacaacacca gggaagctgt ttaaagcaag catagcccct acacccgtac
    19381 cacagccggt aacaacaaag tcaactgcct ttgtatttaa aaggatggca gccattagtc
    19441 cgttctgcac ataagttaat tgactttctc cttcttctcc acgcatacca tagttaaata
    19501 attggtagtc ttttttatct gtcgcttctt ttagactatc gtaaataatg tgattcttgc
    19561 tagcttgact attttcattg attaatgcga ttttcataag atcttctttc tatttttact
    19621 caggttgttt tccgatgtag gctaagatac cgccatctac atataggatg tggccattga
    19681 caaaattgct ggcatcacta gcgagaaaga cagcagggcc catcaaatct tcaggatttc
    19741 cccaacgtgc agcaggtgtt tttgcaatga tgaactggtc aaatgggtgg cgagaaccat
    19801 cttcttgcaa ctcacgaaga ggtgctgttt gaggagtggc aatataaccc ggtccaattc
    19861 cgttacattg gatattggct ccaccgtatt cagacgcaat gttgcgggtc aacattttca
    19921 agcccccttt agcagcagca taagcgctaa ctgtttcacg tcccagttcg ctcatcatcg
    19981 aacaaatatt gataatcttt ccatgccctt tctttatcat agaaggaata actgcctttg
    20041 aaacgataaa tggtgcgttt aagtcaatat cgatgacctt acggaaatca gcggcgctca
    20101 tttcgcacat tggaactcgg cggataatac cagcgttatt aacgaggatg tcaatgacac
    20161 caacctcttg ttcgatttgc ttgaccatgg cttggatacc gtcctcgtct gtcacgtcac
    20221 agacatatcc atgggcttcg atgccaactt cacgataagc ttcaatccct ttattgacca
    20281 gatcttgatt gatatcgtta aagacaatag tagcgccggc ttcagcgtag gatttggcaa
    20341 tagcaaatcc aattccataa gaagcgccgg tgatgagagc aatttttcct tttaaagaaa
    20401 actgctcaat tgagaatgat gtatttgtca tttgatactt cctttcaaat ttgttaagac
    20461 ttctctataa ccaaattata ttctagcaaa ccggttttgt caataaataa atatttttat
    20521 ttataaaaag atttgttttc ctgaaaaacg gaatgttttg aaatttctgt ttattaaaat
    20581 ggttaaaaag ataatgaaag cgctaatatt tttttaaaaa aactattgac aagataaaaa
    20641 taaaggatta caatggggaa tataaagtaa accggtaaac ctaaacaaga aaggagaaaa
    20701 gatgaaaatt gtacttgtag ggcatggaca ttttgctaca gggatttata gttctttaca
    20761 attgattgca ggtaatcaag aaaatgtgga ggcgattgac tttgtggaag gaatgtcagc
    20821 agatgaactc aagcaaaaaa tcttacttgc aatttcaaat gaagaagaag ttttaatcct
    20881 aagtgatctc ttgggaggat cgccattcaa ggtttcttct accataatgg gagaaaatcc
    20941 agtcaaaaca atgaatgttc tctcgggttt gaacttagcc atgttaatgg aagcagtctt
    21001 tgctagaatg gctcatagct ttgatgaggt tgttaataaa tcagtagtgg cggcccaggg
    21061 cggagtcgta aatggtaaag aattgttttc aacggatgca gaggaagaag atttcgaatc
    21121 gggtatttaa agggtaaaag aatgataaaa aaggttacga ttgaaaaaat aaaatcgcct
    21181 gagcgcttct tagaagtacc acttctgacg aaagaagaag tcggccaggc aatcgataag
    21241 gttattcggc agttagaact caaccttgac tatttcaagg aagatttccc gacgccagct
    21301 acctttgata atgtctatcc aatcatggat aacacggaat ggaccaatgg tttctggaca
    21361 ggagaactgt ggttggctta tgaatacagt caacaggatg catttaaaaa catcgctcat
    21421 aaaaatgttc tttctttcct ggatcgtgtc aataagagag tagaattgga tcaccatgat
    21481 ctcggcttct tgtacacacc gtcttgtatg gctgaatata agataaatgg agatggagag
    21541 gctagagaag caaccttgaa agctgcagat aagttgattg aacgctatca agaaaaaggt
    21601 ggttttattc aagcttgggg agacttgggc aagaaagagc attaccgttt gattatcgac
    21661 tgcttgctca atatccaact cttattcttt gcttatcaag aaacaggcga tcaaaaatac
    21721 tacgatattg cagaaagtca tttctatgct tcagctaata atgtaatccg tgatgacgct
    21781 tcgtccttcc acaccttcta ttttgatcct gagacaggtc aaccctttaa aggtgtaacg
    21841 agacaagggt atagtgatga ttcatgctgg gcacgtggtc aatcatgggg agtctatggt
    21901 attcctttga cttatcgtca cttaaaagac gagtcctgct ttgacttgtt taagggtgtg
    21961 accaattatt tcttgaatcg tctgccaaaa gatcatgtgt cctattggga tttgattttt
    22021 aatgatggta gtgctcaatc acgagattct tcagcaacag ctatcgccgt ctgtgggatt
    22081 catgaaatgc taaaacatct cccagaggtg gatgctgaca aagatattta taaacatgct
    22141 atgcatgcca tgcttcgttc cttgatcgaa cattatgcaa atgatcaatt tacccctggt
    22201 gggacaagtc ttctccacgg tgtgtactca tggcattcag gtaaaggagt ggatgaaggc
    22261 aatatctggg gtgactacta ttacctagaa gcccttatcc gtttctacaa agactggaac
    22321 ctatattggt aggaggagaa atatgacaat gccaaatatt attatgaccc gtatcgatga
    22381 acggttgatt catggacaag gacaactttg ggtaaaatac ctagcttgta atacggtcat
    22441 tgttgccaat gacgaagtaa gcacggacaa gatgcaacaa actctgatga aaacagttgt
    22501 gccagactca gttgccatgc gtttcttccc tttgcaaaag gtgattgata tcattcacaa
    22561 ggctaatcct gctcaaacga tctttatcgt tgtaaaggat gtaaaggacg ctttaacctt
    22621 ggtagaaggt ggtgtcccta tcaaagaaat caatattggg aacattcaca atgcccctgg
    22681 taaagagcaa gtgacacgct ccatcttcct gggtgaagag gacaaggcag ccctcaagga
    22741 attaagccaa actcatcaag taacatttaa tacgaaaaca actccaacag gaaatgatgg
    22801 agctgttcaa gtcaacatta tggactatat ttaaaagagg agatcgttat gtcgattaat
    22861 gtatttcaag cgattttaat tggattatgg acagctttct gttttagtgg aatgctgtta
    22921 ggaatttaca ccaatagatg tattgttctg tcatttggtg tcggaattat tctaggtgat
    22981 ctgcctactg ctcttgcaat gggagctatt ggtgaattgg cttatatggg attcggtgtt
    23041 ggtgctggag gtactgttcc accaaaccca atcggacctg gtatctttgg taccttgatg
    23101 gctatcacta gtgctggtaa agtcagtcca gaagcggctc ttgccctctc tactccgatt
    23161 gctgtggcga ttcaattctt acaaactttc gcctacactg tacgtgctgg tgcgcctgaa
    23221 acggcgatga agcacttgaa aaaccataat ttgaagaaat tcaagtttac tctaaatgca
    23281 acaatttggt tgtttgcctt tattggattt accttgggtt gcttgggtgc cctttcaatg
    23341 gataccttgt tgaaactcgt agactacatt ccaccggtat tacttacagg tttgacagtt
    23401 gctggtaaaa tgctcccagc tatcggtttt gcgatgatct tgtcagtgat ggctaagaaa
    23461 gagttgattc cctttgtctt gttgggatat gtttgtgcag cttatctaaa catcccaaca
    23521 attggtattg caattgtagg tactatcttt gctttgattg aattttataa caagccaaaa
    23581 acagcgaatc atgtggtaga ggaggaagca cacgatgact ggatctaaca aattaacaaa
    23641 acgtgattat cttaaaacgt ctttgcgggc attcttttgt caaaatggat ttaactatag
    23701 taactatcaa gggttgggat atgccaatgt gatgtatcct gctttgaaaa aacactatgg
    23761 agaggatcag gaaggtttct accaagcctt ggaagaaaac tgtgaattct ataataccaa
    23821 cccacacttc ctgcctttta ttaccagctt gcatcttgta atgttggaaa atggccgtcc
    23881 ggcaaaagaa acacgtagca tcaagatggc cttgatggga ccattggcag gtattgggga
    23941 ttctctttct caattctgtt tagctccatt gttctcaacc atcgcagctt cgtttgctca
    24001 agaaggcttg gttgtcggtc caatcttgtt cttccttgcg atgaatacga ttttaacagc
    24061 gattaaattg tcaactggtc tgtatggata caaactagga acaactgtga ttgataaact
    24121 aagcgaacag atggcaacga tttctcgtat tgccaatatt atcggtgtaa ccgtaattgc
    24181 tggtttggca gcgacatctg ttaagattat ggtgccgatt acctttgctg caggggaagt
    24241 taaagcagac gctaaacaaa gtatcgtaag tattcaggga atgcttgata aggttgctcc
    24301 agctcttcta ccagccctat ttacactttt agtttactac ttgatcaaag aaaagaaatg
    24361 gacaacatat aaactcgtta ttttaacagt tgtcatcgga attatcggaa gctggcttaa
    24421 gattatagct taatggatac aacattgttt tatggaatag tgattgtctt ggcagtgagt
    24481 ccccttttac tgtcaagctt tcattctatt cgtcagcaaa agttgcttcg caaacagacg
    24541 gagcaacgac aagagtattt agcttcttta acatctggtg atgaagtgtt gttattgtct
    24601 ggaattcatg gaaaaatcat ttctatcaaa gatgacttgg tctccttgca gattgcaaaa
    24661 ggtgtggtca tctatgtaga aaaggaaagt gtaatgggaa agacaaaaga actgcttttt
    24721 aagtagttct ttttctggta atagataatg aaagaagaaa gaagacaatt ttttgaaaga
    24781 gtcgatggaa accaatgtcg tgattatatc ttgtcgcact gttcaaaaga ctatgagaaa
    24841 gtcaagagtt cccttgaacg cttgatggac aatcgtttta tgtttgatag tccttgggat
    24901 atggagcctt gttcaaaaat ccatcaaatc cagccgatgg tatgggatca agtatttgaa
    24961 gatgatccag aatgggctta tatgctcaat cgacaagaat atctcttgca gtttatgata
    25021 gggtatgtgg tagaaggaga taaggactat attcaaaagt gcaagttctt tctatttgat
    25081 tggattgagc aggtgagaga attttctcct caatccttga tgactagaac cttggatacg
    25141 ggtattcgtt cctttacttg gttgaaacta ctcttgctcc tcttgaaatt tgacatgcta
    25201 gaggagaaag aactagagaa aattttggtc agtctagaaa agcagattga ctttatgaaa
    25261 agctactatc gcgccaagta cacccttagt aactggggga ttttacaaac aattccgatg
    25321 cttgctatct attatttctt ttcagataag atggacctag aagaagctta ccattttgct
    25381 tcagaggagt tgaaacagca aattgagaca cagattttag gagatggaag ccagtttgaa
    25441 cagtcgattc tctatcatgt agaggtttat aaagccttgc tggatttgtg tctcttgctt
    25501 ccagacttgc aagatagtta ccgagagttg ctggaaaaga tggcgaccta tattcaaatg
    25561 atgacaggct tagatggacg aactttggct tttggtgata gcgattctac agaaacgaca
    25621 gaaattttga gcctgtctgc tgtggttttg aacaaggaag accttcttaa cggtctggat
    25681 gttaaagtcg atttgcttag cctcttgttc ctggggcgag aaaaggtcaa gcgactgcag
    25741 gaatttgaaa agagagcttg gcagcctaag tccatgatct ttgaagactc tggacatgtc
    25801 tgcattaagg atgaacatcg ttatctattt ttcaaaaatg gtccgctagg aagtgcccat
    25861 agccatagtg acgagaatag tttttgctta cagtatcaag gacaacctat tttcatagat
    25921 gctgggcgtt attcttatcg ggagatatat gaacgttatc tcttaaagag tgcttggagt
    25981 cattcgacct gcattgtaga tgggaaagct ccggaaagaa tcacgggatc ctgggaatat
    26041 gaatactatc ctcactccct gttttgtcac cataaagaaa gggagggagt gcattatatt
    26101 gaaggggctt attggtcagc agaacctgat ttgccttatc ttcacaagag aaaaatcctc
    26161 atgttggtag aggatgtctg gctcttggtg gatgacatca ggtgtcaagg tcagcatgag
    26221 gcgttgactc agtttatcct tgacaaggat gtgacctatc aagatgggaa aatcaatcag
    26281 ttgagactat ggagtgaagt tgattttgat ttggaagata ccatcatttc tcctaaatac
    26341 aatgagcttg aaagaagtaa caaactcacc aagcgccaat tctttgagaa tcagatgctg
    26401 gattatacca tcattgcgca tgagagtttt gaaatcatcc gtcattctgt ctaccagaca
    26461 gatgatcgtg aagtggaaaa tgctctggct tttgaagtga aaaatgacga aacagacaag
    26521 ctgattctgt tattaagcga ggatatttgt gtaggtgaaa aattgtgcct cgttgacgga
    26581 acaaaaatgc gtggaaaatg tctagtatat gataaaataa atgagagaat gattcgcttg
    26641 cagtgctaga aataggcatt ttgaatagtg aatatgttat aataagtatt agtaggaggt
    26701 gttttagatt ggagaagaaa ctgaccataa aagacattgc ggaaatggct cagacctcga
    26761 aaacaaccgt gtcattttac ctaaacggga aatatgaaaa aatgtcccaa gagacacgtg
    26821 aaaagattga aaaagttatt catgaaacaa attacaaacc gagcattgtt gcgcgtagct
    26881 taaactccaa acgaacaaaa ttaatcggtg ttttgatcgg tgatattacc aacagtttct
    26941 caaaccaaat tgttaaggga attgaggata tcgccagcca gaatggctac caggtaatga
    27001 taggaaatag taattacagc caagagagtg aggaccggta tattgaaagc atgcttctct
    27061 tgggagtaga cggctttatt attcagccga cctctaattt ccgaaaatat tctcgtatca
    27121 tcgatgagaa aaagaagaaa atggtctttt ttgatagtca gctctatgaa caccggacta
    27181 gctgggttaa aaccaataac tatgatgccg tttatgacat gacccagtcc tgtatcgaaa
    27241 aaggttatga gcattttctc ttgattacag cggatacgag tcgtttgagt actcggattg
    27301 agcgggcaag tggttttgtg gatgctttaa cagatgctaa tatgcgtcac gccagtctaa
    27361 ccattgaaga taagcatacg aatttggaac aaattaagga atttttacaa aaagaaatcg
    27421 atcccgatga aaaaactctg gtatttatcc ctaactgttg ggccctacct ctagtcttta
    27481 ccgttatcaa agagttgaat tataacttgc cacaagttgg gttgattggt tttgacaata
    27541 cggagtggac ttgcttttct tctccaagtg tttcgacgct ggttcagccc tcctttgagg
    27601 aaggacaaca ggctacaaag attttgattg atcagattga aggccgtaat caagaagaaa
    27661 ggcaacaagt cttggattgt agtgtgaatt ggaaagagtc gactttctaa aatgaaggaa
    27721 aatgacttgc aatctctgtt aagaaataaa ataatcccac ctagaacaag ctaggtggga
    27781 ttatttgctt atgaaatgag aaattatggg agcaagctcc taaatcaact gtttttgatc
    27841 tacttcttta actacttgat aaaagttata gaagtaggcc aaacttgaaa tgatggttac
    27901 gactaggaat attgaaaatt tccattggac agggttggtt aaaagttgtg gaaaggatat
    27961 gaggagaaag aagagggctg cgttgaggac aggtatccgt tttgattgta ttttctcaag
    28021 tcctttattg agcgcaggaa gaaagaggag taggagtagt aaaactgtat gagaaacagc
    28081 tcctgaaata agggcgaaga aaaggaaaat actgataaaa acatgaatgt tcagtagtct
    28141 agctagtgat ttcataaggc acctcctaat cctggtcttt tttagctctt gcaatacgaa
    28201 gtgagtcgac aatatgtatc atcactccga aaaagaaagc tcccagtata gttttaaaaa
    28261 tatgttttgt atttagaaga gaactgataa aatttggatt ttcacttgtt agggtatcaa
    28321 tgagtggaat tataaaaaat atcactgttc cataaatcga acctgctttc agaccaggat
    28381 aacgtaactg tttcttttct tttttcatga gtttcctcct aatcctcatc ttgatttttc
    28441 ttagtttttg caatgcgacg ggagatgagg aactgtatgc tcgctccgaa gaaaatagaa
    28501 ccgagaatac ttgatacacc atttcttata gtgagaagag aatgaaaata gtcctgacct
    28561 tcatctatga gtatactgag aagaggagtt ataaaaaaca tccatagacc aaagaacaaa
    28621 cctgctttca gacctgggta gtgtagttgc ttgctttctt tctcattcag catatctggt
    28681 tcaatgactg tgatgcctgt ttttttcatt tggtaggtga catagccagc agcgatgagg
    28741 gcaatcacta aaatcagagg aggatagatt agagccactt cttgagggta tttataggct
    28801 agaaggagtg gaataagatt tccgaaaatc atcagataaa agaggacgat aaagacttgg
    28861 ttcccaatac tatcggcctc acgccgtttg tattcgtcaa ggggaccaga aataccgtat
    28921 gtgcgtttga tcagtttttc agtgaaggtt tcttttttca tgagtttgct ccttttttaa
    28981 aaatcttcct cccaaaagag actgttgagg tcagtttgga ggctgcgggc gagattgaga
    29041 cagagttcca aggttggatt gtacttgtcg ttttcaatca tattgatagt ctgtctcgag
    29101 acaccgatat ccttggcgag ttcgagctgg gaaataccca attccttgcg aaattctttc
    29161 acacgattca tctggtctcc tttctgattt atgtcgtata tatttgacta tattatagtc
    29221 ttttaaacat aaagtgtcaa gtatatttga catatttttt gaagaaatag tagtctcctt
    29281 gtcctatttg tctgacaagt gcaagctggt cggatttgtg gtaaaataga taagatatga
    29341 caaaagaatt tcatcatgta acggtcttac tccacgaaac gattgatatg cttgacgtaa
    29401 aacctgacgg tatctacgtt gatgcgactt tgggtggagc aggccatagc gagtatttat
    29461 taagtaaatt aagtgaaaaa ggccatctct atgcctttga ccaggatcag aatgccattg
    29521 acaatgcgca aaaacgcttg gcaccttaca ttgagaaggg aatggtgacc tttatcaagg
    29581 ataacttccg tcatttacag gcacgtttgc gcgaagctgg tgttcaggaa attgatggaa
    29641 tttgttatga cttgggagtg tctagtcctc aattggacca gcgtgagcgt ggtttttctt
    29701 ataaaaagga tgcgccactg gacatgcgga tgaatcagga tgctagtctg acagcctatg
    29761 aagtggttaa tcactatgac tatcatgatt tggttcgtat tttcttcaaa tacggtgagg
    29821 ataaattctc taaacagatt gcgcgtaaga ttgagcaagc gcgtgaagtg aagccgattg
    29881 agacaacgac tgagttagca gagattatca agttggtcaa acctgccaag gaactcaaga
    29941 agaagggtca tcctgctaag cagattttcc aggctattcg aattgaagtc aatgatgaac
    30001 tgggagcggc agatgagtcc atccagcagg ctatggatat gttggctctg gatggtagaa
    30061 tttcagtgat tacctttcat tccttagaag accgcttgac caagcaattg ttcaaggaag
    30121 cttcaacagt tgaagttcca aaaggcttgc ctttcatccc agatgatctc aagcccaaga
    30181 tggaattggt gtcccgtaag ccaatcttgc caagtgcgga agagttagaa gccaataacc
    30241 gctcgcactc agccaagttg cgcgtggcca gaaaaattca caagtaagag ggaaaaagat
    30301 ggcagaaaaa atggaaaaaa caggtcaaat actacagatg caacttaaac ggttttcgcg
    30361 tgtggaaaaa gctttttact tttccattgc tgtaaccact cttattgtag ccattagtat
    30421 tatttttatg cagaccaagc tcttgcaagt gcagaatgat ttgacaaaaa tcaatgcgca
    30481 gatagaggaa aagaagaccg aattggacga tgccaagcaa gaggtcaatg aactattacg
    30541 tgcagaacgt ttgaaagaaa ttgccaattc acacgatttg caattaaaca atgaaaatat
    30601 tagaatagcg gagtaagata tgaagtggac aaaaagagta atccgttatg cgaccaaaaa
    30661 tcggaaatcg ccggctgaaa acagacgcag agttggaaaa agtctgagtt tattatctgt
    30721 ctttgttttt gccatttttt tagtcaattt tgcggtcatt attgggacag gcactcgctt
    30781 tggaacagat ttagcgaagg aagctaagaa ggttcatcaa accacccgta cagttcctgc
    30841 caaacgtggg actatttatg accgaaatgg agtcccgatt gctgaggatg caacctccta
    30901 taatgtctat gcggtcattg atgagaacta taagtcagca acgggtaaga ttctttacgt
    30961 agaaaaaaca caatttaaca aggttgcaga ggtctttcat aagtatctgg acatggaaga
    31021 atcctatgta agagagcaac tctcgcaacc taatctcaag caagtttcct ttggagcaaa
    31081 gggaaatggg attacctatg ccaatatgat gtctatcaaa aaagaattgg aagctgcaga
    31141 ggtcaagggg attgatttta caaccagtcc caatcgtagt tacccaaacg gacaatttgc
    31201 ttctagtttt atcggcctag ctcagctcca tgaaaatgaa gatggaagca agagcttgct
    31261 gggaacctct ggaatggaga gttccttgaa cagtattctt gcagggacag acggcattat
    31321 tacctatgaa aaggatcgtc tgggtaatat tgtacccgga acagaacaag tttcccaacg
    31381 aacgatggac ggtaaggatg tttatacaac catttccagc cccctccagt cctttatgga
    31441 aacccagatg gattcttttc aagagaaggt aaaaggaaag tacatgacag cgactttggt
    31501 cagtgctaaa acaggggaaa ttctggcaac aacgcaacga ccgacctttg atgcagatac
    31561 aaaagaaggc attacagagg actttgtttg gcgtgatatc ctttaccaaa gtaactatga
    31621 gccaggttcc actatgaaag tgatgatgtt ggctgctgct attgataata atacctttcc
    31681 aggaggagaa gtctttaata gtagtgagtt aaaaattgca gatgccacga ttcgagattg
    31741 ggacgttaat gaaggattga ctggtggcag aatgatgact ttttctcaag gttttgcaca
    31801 ctcaagtaac gttgggatga ccctccttga gcaaaagatg ggagatgcta cctggcttga
    31861 ttatcttaat cgttttaagt ttggagttcc gacccgtttc ggtttgacgg atgagtatgc
    31921 tggtcagctt cctgcggata atattgtcaa cattgcgcaa agctcatttg gacaagggat
    31981 ttcagtgacc cagacgcaaa tgattcgtgc ctttacagct attgctaatg acggtgtcat
    32041 gctggagcct aaatttatta gtgccgttta tgatccaaat gatcaaactg ctcggaaatc
    32101 tcaaaaagaa attgtgggaa atcctgtttc taaagatgca gctagtctaa ctcggactaa
    32161 catggttttg gtagggacgg atccggttta tggaaccatg tataaccaca gcacaggcaa
    32221 gccaactgta actgttcctg ggcaaaatgt agccctcaag tctggtacgg ctcagattgc
    32281 tgacgagaaa aatggtggtt atctagtcgg gttaaccgac tatattttct cggctgtatc
    32341 gatgagtccg gctgaaaatc ctgattttat cttgtatgtg acggtccaac aacctgaaca
    32401 ttattcaggt attcagttgg gagaatttgc caatcctatc ttggagcggg cttcagctat
    32461 gaaagactct ctcaatcttc aaacaacagc taaagctttg gagcaagtaa gtcaacaaag
    32521 tccttatcct atgcctagtg tcaaggatat ttcacctggt gatttagcag aagaattgcg
    32581 tcgcaatctt gtacaaccca tcgttgtggg aacaggaacg aagattaaaa acagttctgc
    32641 tgaagaaggg aagaatcttg ccccgaatca gcaagtcctt atcttatctg ataaagtaga
    32701 ggaagttcca gatatgtatg gttggacaaa ggagactgct gagacccttg ctaagtggct
    32761 caatatagaa cttgaatttc aaggttcggg ctctactgtg cagaagcaag atgttcgtgc
    32821 taacacagct atcaaggaca ttaaaaaaat tacattaact ttaggagact aatatgttta
    32881 tttccatcag tgctggaatt gtgacatttt tactaacttt agtaggaatt ccggccttta
    32941 tccaatttta tagaaaggcg caaattacag gccagcagat gcatgaggat gtcaaacagc
    33001 atcaggcaaa agctgggact cctacaatgg gaggtttggt tttcttgatt acttctgttt
    33061 tggttgcttt ctttttcgcc ctatttagta gccaattcag caataatatg ggaatgattt
    33121 tgttcatctt ggtcttgtat ggcttggtcg gatttttaga tgactttctc aaggtctttc
    33181 gtaaaatcaa tgaggggctt aatcctaagc aaaaattagc tcttcagctt ctaggtggag
    33241 ttatcttcta tcttttctat gagcgcggtg gcgatatgct ttctgtcttt ggttatcaag
    33301 tgcatctagg gattttctat attgtcttcg ctcttttctg gctagtcggt ttttcaaacg
    33361 cagtaaactt gacagacggt gttgacggtt tagctagtat ttccgttgtg attagtttgt
    33421 ctgcctatgg agttattgcc tatgtgcaag gtcagatgga tattcttcta gtgattcttg
    33481 ccatgattgg tggtttgctc agttttttca tctttaacca taagcctgct aaggtcttta
    33541 tgggtgatgt gggaagtttg gccctaggtg ggatgctggc agctatctct atggctctcc
    33601 accaagaatg gactctcttg attatcggaa ttgtatatgt ttttgaaaca acttctgtta
    33661 tgatgcaagt cagttatttc aaactgacag gtggtaaacg tattttccgt atgacgcctg
    33721 tacatcacca ttttgagctt gggggattgt ctggtaaagg aaatccttgg agcgagtgga
    33781 aggttgactt cttcttttgg ggagttgggc ttctagcaag tctcctgacc cttgcaattt
    33841 tgtatttgat gtaagaatgg caccctgatg tttcagggtg tttttgtgtt taaatacaca
    33901 atgaaaatca aagaacaaac tagaaagcta actttaggct gctcaaaata tagtagattg
    33961 aaactagaat agtacacctc tacttctaaa acatttttag aaatcgattt gactgtcctg
    34021 aacgatttat cctgttctta tttcatttta ctatacagtt ttgagatggt tgatagaact
    34081 gacgaagtca gctcaaaaca ctgttttgag gttgtagaca aggcgaagct gatgtggttt
    34141 gaagaggttt tcgaagagtg taaaaaaata ttggtcagtt aaagtcaaaa ctcttgacct
    34201 tttctgacca atgtagtata ttatgaacgt aaggtaaatg aaagccttac tagaacactt
    34261 atttaaagta aaatagaaag aggtgagtct atgtttcatc tagcaatctt cagaggtaaa
    34321 gatagtctac tcctgcttga aaaagaaaaa ccagaaatag tacgtagggt agcgatctag
    34381 ctagtctaaa ttttttaaaa caatggtcaa agatagtcaa tatcagtaat cataactaag
    34441 taaacaaaaa gaggtaaaga atatgaataa caactttaat aattttaata acatggatga
    34501 tttatttaac caattgatgg gtggtatgcg aggatatagt tctgaaaatc gccgttactt
    34561 aattaatgga cgcgaagtca cacctgagga atttgctcac tatcgtgcga ctggtcaatt
    34621 accaggaaat gcagaaactg atgtgcaaat gccacaacag gcatcaggta tgaaacaaga
    34681 cggtgtcctt gcaaaactag gtcgaaactt aacagcagaa gcgcgtgagg gcaagttgga
    34741 tcctgttatc ggacgaaaca aggaaattca agaaacatct gaaatcctct cacgccgcac
    34801 caagaacaat cctgttttgg tcggagatgc aggtgttggt aagacagcag ttgtcgaagg
    34861 tctagcgcaa gccattgtga acggagatgt tcctgctgct atcaagaaca aggaaattat
    34921 ttccattgat atctcaggtc ttgaggctgg tactcaatac cgtggtagct ttgaagaaaa
    34981 tgtccaaaac ttagtcaatg aagtgaaaga agcagggaat attatcctct tctttgatga
    35041 aattcaccaa attcttggtg ctggtagcac tggtggagac agtggttcta aaggacttgc
    35101 ggatattctc aagccagctc tctctcgtgg agaattgaca gtgattgggg caacaactca
    35161 agacgaatac cgtaacacca tcttgaagaa tgctgctctt gctcgtcgtt tcaacgaagt
    35221 gaaggtcaat gctccttcag cagagaatac ttttaaaatt cttcaaggca ttcgtgacct
    35281 ctatcaacaa caccacaatg tcatcttgcc agacgaagtc ttgaaagcag cggtggatta
    35341 ttctgttcaa tacattcctc aacgtagctt gccagataag gctattgacc ttgtcgatgt
    35401 aacggctgct cacttggcgg ctcaacatcc agtaacagat gtgcatgctg ttgaacgaga
    35461 aatcgaaacg gaaaaagaca agcaagaaaa agcagttgaa gcagaagatt ttgaagcagc
    35521 tctaaactat aaaacacgca ttgcagaatt ggaaaggaaa atcgaaaacc acacagaaga
    35581 tatgaaagtg actgcaagtg tcaacgatgt ggctgaatct gtggaacgaa tgacaggtat
    35641 cccagtatcg caaatgggag cttcagatat cgaacgtttg aaagatatgg ctcatcgctt
    35701 gcaagaaaag gtgattggtc aagataaggc cgtagaagtt gtagctcgtg ctatccgtcg
    35761 taaccgtgct ggttttgatg aaggaaatcg cccaatcggc agcttcctct ttgtagggtc
    35821 tactggggtt ggtaagacgg agcttgctaa gcaattggca ctcgatatgt ttggaaccca
    35881 ggatgcgatt atccgtttgg atatgtctga atacagtgac cgcacagctg tttctaagct
    35941 aattggtaca acagcaggct atgtgggtta tgatgacaat agcaatacct taacagaacg
    36001 tgttcgtcgc aatccatact ctatcattct cttggatgaa attgaaaagg ctgatcctca
    36061 agttattacc cttctcctcc aagttctaga tgatggtcgt ttgacagatg gtcaaggaaa
    36121 tacagtaaac ttcaagaata ctgtcgttat tgcgacctca aatgctggat ttggctatga
    36181 agccaacttg acagaagatg cggataaacc agaattgatg gaccgtttga aacccttctt
    36241 ccgtccagaa ttcctcaacc gctttaatgc agtcatcgag ttctcacact tgactaagga
    36301 agacctttct aagattgtag atttgatgtt ggctgaagtt aaccaaacct tggctaagaa
    36361 agacattgac ttggtagtta gtcaagcggc taaagattat atcacagaag aaggttacga
    36421 cgaagtcatg ggggttcgtc ctctccgtcg cgtggttgaa caagaaattc gtgataaggt
    36481 gacagacttc cacttggatc atttagatgc taaacatctg gaagcagata tggaagatgg
    36541 cgttttggtt attcgtgaga aagcctaaga tagaattttg aggataaaaa agaaggagcc
    36601 agctgaaaaa aactggttcc tttttaggta cgacaggcat gtcgtatagt agaagtgtat
    36661 tattccagtt tcaatatact atagtagctc agaagtcggt acttaaacgt gctatatcaa
    36721 aaccagtcct tgaaaaacgt ggactggttt cgtgtttgga ttattacctt gaacgacatg
    36781 cgttaaaagt tagttgaacc gccgtatgcc gaacggtacg tacggtggtg tgagaggggc
    36841 tagagattat cccctactcg attgtctata gctatagggg taaagttatt agagaggttg
    36901 ctagtttata gagacatctt gatttgtaaa aagttaaatt ttagacaatt atccccttta
    36961 aaaaatctat taaaccatag ctagttgaag taaattttta tagaacataa ttttatttat
    37021 caagacattg tagagttgag gcaaattgaa aaagaaagtt taaaagttga taataagtca
    37081 ataagaaagc tattaattct aacgagatta tttgatagta atttgttttt tcagctacta
    37141 ttcggacaat gttattataa taaacacagg agagaacacc agaaggtagg gacatcagaa
    37201 gaaatagttc aggatatagt taacataatc atcaaagaag ctcctagact cgctaatgtt
    37261 aatttggaaa catattatcc agatgaatat atgtcaaata cattgaagca attactactt
    37321 tttagagagg agttcataaa aaatattttg aatgggattg atgtggatga aacagtagta
    37381 atagaaaatg attttgtaga agagttggag aactttttaa aagagaatga tttgctagat
    37441 ttttcaaata gcatattttt tcagttatct ggagataaag taatagtgaa taatatttat
    37501 ccaggatatt tagcatattt taataggttc cttacatttt atccgaaaat attcgctatt
    37561 aaagaagttg gagaatatat tgacttttta aattttgaaa agagaattgc ggatatgttt
    37621 tattgttggg gatttaatgc aaattctaga gtgttgacag ctgaaaaaat aattgaaatc
    37681 ccaaatcacc aaatcaatgc taagtacata aaaaaagtta taaaaatgag tgaactcttg
    37741 tttggtgttg atagtaataa cagaattcgg ttgcttaaca atagaaggga attgataaaa
    37801 actattttcc aaggttctgt aattaagtca gcaattcctg ctctagctgc tactttggat
    37861 acaatcagta acagtggatc atttcaaatt tctttatcaa agcagataat taataattta
    37921 gtattaagtg gtaaagataa agttacaatt cctaggatag agttagataa tgttgttctt
    37981 tcaagacaga agattattgt atcagtttcg tatataaatg attttttgga tttgagattt
    38041 ccagataaaa tagaatacat tttaaatttt ttagaaggat ctggtttcaa tactaaagta
    38101 atggtctact ttgggaaaat tgtagaagaa gataagaact attttgttaa tcttgaaaaa
    38161 cctcagtatt ttgattttac cagtatactt ttcaataagt tattctttaa agaattaaac
    38221 aagtttgatt acatggttat tgaagaactc attccaaatc ttgatgaaga tgtaatgatg
    38281 acagagtata taaaagagta tactgaatag gagcaatcta ttatgatttt aagtaaagta
    38341 cgttgttaca tatataattc taaaattaga ggtaaagttc tgtatgaatt atatgaattt
    38401 ataaatgaaa ataagcaatt gatggacgca attaattcaa ttaaagttga cagtagtaat
    38461 ggttttagta ttcaaatatt acatttagga gaacagcaaa caactgtctt attaacagat
    38521 ttttttacta aaactttaga cttgtttaag gaatttaggg ttacaaataa gagtactctt
    38581 gagcaggtga aaaatcaaat tagcatacta aattcttctg gtccaaaaat ggatttaac
//
LOCUS       DAVBBO010000015        37669 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ST1
            SAMEA2066453-rid20184263.denovo.015, whole genome shotgun sequence.
ACCESSION   DAVBBO010000015 DAVBBO010000000
VERSION     DAVBBO010000015.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2066453
            Sequence Read Archive: ERR351777
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 37669)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 37669)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980402.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980402.1
            Genome Coverage       :: 176x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:17:33
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,141
            CDSs (total)                      :: 2,104
            Genes (coding)                    :: 1,953
            CDSs (with protein)               :: 1,953
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 16S)
            partial rRNAs                     :: 1 (23S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 151
            CDSs (without protein)            :: 151
            Pseudo Genes (ambiguous residues) :: 0 of 151
            Pseudo Genes (frameshifted)       :: 73 of 151
            Pseudo Genes (incomplete)         :: 76 of 151
            Pseudo Genes (internal stop)      :: 40 of 151
            Pseudo Genes (multiple problems)  :: 32 of 151
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..37669
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2066453-rid20184263.denovo.015"
                     /strain="ST1"
                     /db_xref="taxon:1313"
     gene            108..896
                     /gene="codY"
                     /locus_tag="VQU30_000752"
     CDS             108..896
                     /gene="codY"
                     /locus_tag="VQU30_000752"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP-sensing pleiotropic transcriptional
                     regulator CodY"
                     /protein_id="HET2446892.1"
                     /translation="MAHLLEKTRKITSILKRSEEQLQDELPYNAITRQLADIIHCNAC
                     IINSKGRLLGYFMRYKTNTDRVEQFFQTKIFPDDYVQGANMIYETEANLPVEHDMSIF
                     PVESRDDFPDGLTTIAPIHVSGIRLGSLIIWRNDKKFEDEDLVLVEIASTVVGIQLLN
                     FQREEDEKNIRRRTAVTMAVNTLSYSELRAVSAILGELNGNEGKLTASVIADRIGITR
                     SVIVNALRKLESAGIIESRSLGMKGTYLKVLISDIFEEVKKRDY"
     gene            896..1471
                     /locus_tag="VQU30_000753"
     CDS             896..1471
                     /locus_tag="VQU30_000753"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255720.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine hydrolase"
                     /protein_id="HET2446893.1"
                     /translation="MTKALISIDYTEDFVADSGKLTAGAPAQAISDAISKVTRLAFER
                     GDYIFFTIDAHEENDFFHPESKLFPPHNLIGTSGRNLYGDLGIFYQEHGSDSRVFWMD
                     KRHYSAFSGTDLDIRLRERRVSTVILTGVLTDICVLHTAIDAYNLGYDIEIVKPAVAS
                     IWPENHQFALGHFKNTLGAKLVDENLNELSE"
     gene            1553..1638
                     /locus_tag="VQU30_000754"
     tRNA            1553..1638
                     /locus_tag="VQU30_000754"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1587..1589,aa:Leu,seq:aag)
     gene            1921..3051
                     /gene="ugpC"
                     /locus_tag="VQU30_000755"
     CDS             1921..3051
                     /gene="ugpC"
                     /locus_tag="VQU30_000755"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003010064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sn-glycerol-3-phosphate ABC transporter
                     ATP-binding protein UgpC"
                     /protein_id="HET2446894.1"
                     /translation="MVELNLKNIYKKYPNSEHYSVEDFNLNIKDKEFIVFVGPSGCGK
                     STTLRMIAGLEDITEGTASIDGVVVNDVAPKDRDIAMVFQNYALYPHMTVYDNMAFGL
                     KLRKYSKEDINKRVQEAAEILGLKEFLERKPADLSGGQRQRVAMGRAIVRDAKVFLMD
                     EPLSNLDAKLRVSMRAEIAKIHRRIGATTIYVTHDQTEAMTLADRIVIMSATKNPAGT
                     GTIGRVEQIGTPQEVYKNPVNKFVAGFIGSPAMNFINVKLVGSEIVSDGFRLKVPEGA
                     LKVLREKGYEGKELIFGIRPEDVNAEPAFLETFPDCVVKATISVSELLGSESHLYCQV
                     GKDEFVAKVDARDYLQTGATVELGFDLNKAHFFDVETEKTIY"
     gene            complement(3198..3344)
                     /locus_tag="VQU30_000756"
     CDS             complement(3198..3344)
                     /locus_tag="VQU30_000756"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397501.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2446895.1"
                     /translation="MEIKEQTRKLAVSCSKYIFEVADKTDEISNHTYGKATLTWFEEI
                     FEEY"
     gene            3552..4310
                     /locus_tag="VQU30_000757"
     CDS             3552..4310
                     /locus_tag="VQU30_000757"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001848902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methyltransferase domain-containing protein"
                     /protein_id="HET2446896.1"
                     /translation="MSEAGHKFLAKLGKKRLRPGGKRATDWLIAEGGLSKEKRILEVA
                     CNRGTTAIELAQRFGCKITAVDMDAQALEVAKKSAGTAGVAHLISFERANAMKLPYQD
                     ASFDIVINEAMLTMQADQAKKKCVMEYLRVLKPGGLLLTHDVLLKEAKESIRQELSQA
                     IHVNVGPLTQDGWEQVMIESGYCDVKVLTGEMTLMKLSGMIYDEGWLGTLKICVNACK
                     KENRKQFLTMYKMFAKNKQKLGFIAMASYKSSKR"
     gene            4397..4909
                     /locus_tag="VQU30_000758"
     CDS             4397..4909
                     /locus_tag="VQU30_000758"
                     /EC_number="2.4.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001049318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenine phosphoribosyltransferase"
                     /protein_id="HET2446897.1"
                     /translation="MNLKDYIATIENYPKEGITFRDISPLMADGNAYSYAVREIVQYA
                     TDKKVDMIVGPEARGFIVGCPVAFELGIGFAPVRKPGKLPREVISADYEKEYGVDTLT
                     MHADAIKPGQRVLIVDDLLATGGTVKATIEMIEKLGGVMAGCAFLVELDELNGREKIG
                     DYDYKVLMHY"
     gene            5091..6035
                     /locus_tag="VQU30_000759"
     CDS             5091..6035
                     /locus_tag="VQU30_000759"
                     /EC_number="2.3.1.46"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001122710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="homoserine O-succinyltransferase"
                     /protein_id="HET2446898.1"
                     /translation="MPIRIDKKLPAVEILRTENIFVMDDQRAAHQDIRPLKILILNLM
                     PQKMVTETQLLRHLANTPLQLDIDFLYMESHRSKTTRSEHMETFYKTFPEVKDEYFDG
                     MIITGAPVEHLPFEEVDYWEEFRQMLEWSKTHVYSTLHICWGAQAGLYLRYGVEKYQM
                     DSKLSGIYPQDTLKEGHLLFRGFDDSYVSPHSRHTEISKEEVLNKTNLEILSEGPQVG
                     VSILASRDLREIYSFGHLEYDRDTLAKEYFRDRDAGFDPHIPENYFKDDDVNQVPCLC
                     WSSSAALFFSNWVNHAVYQETPFDWRKIEDDASAYGYL"
     gene            6044..6721
                     /locus_tag="VQU30_000760"
     CDS             6044..6721
                     /locus_tag="VQU30_000760"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DnaD domain-containing protein"
                     /protein_id="HET2446899.1"
                     /translation="MTYLDAFKSGTLVLPSALLLHFKELFPSSDDFLVWQFFYLQNTT
                     GLEEMSPSQIAERIGKEISDVNQSISNLTERGLLQYRTIELNGEIELLFDASLALERL
                     DDLFGAVRSSSDQLTPQNQLKDLVETFQQELGRLLTPFEIEDLTKTLKEDGTSADLIK
                     EALREAVLNGKPNWKYIQAILRNWRHEGIKSVAQIEAKRAEREASNPQLTQVSADFRN
                     AMDLWKD"
     gene            6819..7577
                     /locus_tag="VQU30_000761"
     CDS             6819..7577
                     /locus_tag="VQU30_000761"
                     /EC_number="5.3.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000087908.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="triose-phosphate isomerase"
                     /protein_id="HET2446900.1"
                     /translation="MSRKPFIAGNWKMNKNPEEAKAFVEAVASKLPSSDLVEAGIAAP
                     ALDLTTVLAVAKGSNLKVAAQNCYFENAGAFTGETSPQVLKEIGTDYVVIGHSERRDY
                     FHETDEDINKKAKAIFANGMLPIICCGESLETYEAGKAAEFVGAQVSAALAGLTAEQV
                     AASVIAYEPIWAIGTGKSASQDDAQKMCKVVRDVVAADFGQEVADKVRVQYGGSVKPE
                     NVASYMACPDVDGALVGGASLEAESFLALLDFVK"
     gene            7615..9120
                     /gene="lytC"
                     /locus_tag="VQU30_000762"
     CDS             7615..9120
                     /gene="lytC"
                     /locus_tag="VQU30_000762"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_078138769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choline binding-anchored murein hydrolase LytC"
                     /protein_id="HET2446901.1"
                     /translation="MSVTFFIGEERLKTKIGLASICLLGLATSHVAANETEVAKTSQD
                     TTTASSSSEQNQSSNKTQTSTEVQTNAAAHWDGDYYVKDDGSKAQSEWIFDNYYKAWF
                     YINSDGRYSQNEWHGNYYLKSGGYMAQNEWIYDSNYKSWFYLKSDGAYAHQEWQLIGN
                     KWYYFKKWGYMAKSQWQGSYFLNGQGAMMQNEWLYDPAYSAYFYLKSDGTYANQEWQK
                     VGGKWYYFKKWGYMARNEWQGNYYLTGSGAMATDEVIMDGARYIFAASGELKEKKDLN
                     VGWVHRDGKRYFFNNREEQVGTEHAKKIIDISEHNGRINDWKKVIDENEVDGVIVRLG
                     YSGKEDKELAHNIKELNRLGIPYGVYLYTYAENETDAESDAKQTIELIKKYNMNLSYP
                     IYYDVENWEYVNKSKRAPSDTGTWVKIINKYMDTMKQAGYQNVYVYSYRSLLQTRLKH
                     PDILKHVNWVAAYTNALEWENPHYSGKKGWQYTSSEYMKGIQGRVDVSVWY"
     gene            9616..10134
                     /locus_tag="VQU30_000763"
     CDS             9616..10134
                     /locus_tag="VQU30_000763"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000229877.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA starvation/stationary phase protection
                     protein"
                     /protein_id="HET2446902.1"
                     /translation="MVELKKEAVKDVTSLTKAAPVALAKTKEVLNQAVADLYVAHVAL
                     HQVHWYMHGRGFLVWHPKMDEYMEALDGQLDEISERLITLGGSPFSTLTEFLQNSEIE
                     EEAGEYRNVEESLERVLVIYRYLSELFQKGLDVTDEEGDDVTNGIFAGAKTETDKTIW
                     MLAAELGQAPGL"
     gene            10264..10770
                     /locus_tag="VQU30_000764"
     CDS             10264..10770
                     /locus_tag="VQU30_000764"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000162460.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrofolate reductase"
                     /protein_id="HET2446903.1"
                     /translation="MTKKIVAIWAQDEEGVIGKENRLPWHLPAELQHFKETTLNHAIL
                     MGRVTFDGMGRRLLPKRETLILTRNPEEKIDGVATFQDVQSVLDWYQAQEKNLYIIGG
                     KQIFQAFEPYLDEVIVTHIHARVEGDTYFPEELDLSLFETVSSKFYAKDEKNPYDFTI
                     QYRKRKEV"
     gene            10770..10940
                     /locus_tag="VQU30_000765"
     CDS             10770..10940
                     /locus_tag="VQU30_000765"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000442275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2446904.1"
                     /translation="MERSLFGLFTAFLCFICFLAGAQAFRKKRYGLSILLWLNAFTNL
                     VNSIHAFYMTLF"
     gene            10972..12204
                     /gene="clpX"
                     /locus_tag="VQU30_000766"
     CDS             10972..12204
                     /gene="clpX"
                     /locus_tag="VQU30_000766"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002874765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit
                     ClpX"
                     /protein_id="HET2446905.1"
                     /translation="MSTNRKNDMMVYCSFCGKNQEEVQKIIAGNNAFICNECVELAQE
                     IIREELVEEVLADLSEVPKPIELLHILNHYVIGQDRAKRALAVAVYNHYKRINFHDTR
                     EESEDVDLQKSNILMIGPTGSGKTFLAQTLAKSLNVPFAIADATALTEAGYVGEDVEN
                     ILLKLLQVADFNIERAERGIIYVDEIDKIAKKSENVSITRDVSGEGVQQALLKIIEGT
                     VASVPPQGGRKHPQQEMIQVDTKNILFIVGGAFDGIEEIVKQRLGEKVIGFGQNNKAI
                     DENSSYMQEIIAEDIQKFGIIPELIGRLPVFAALEQLTVDDLVRILKEPRNALVKQYQ
                     TLLSYDDVELEFDDEALQEIANKAIERKTGARGLRSIIEETMLDVMFEVPSQENVKLV
                     RITKETVDGTDKPILETA"
     gene            12213..12800
                     /locus_tag="VQU30_000767"
     CDS             12213..12800
                     /locus_tag="VQU30_000767"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002915299.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YihA family ribosome biogenesis GTP-binding
                     protein"
                     /protein_id="HET2446906.1"
                     /translation="MELNTHNAEILLSAANKSHYPQDELPEIALAGRSNVGKSSFINT
                     MLNRKNLARTSGKPGKTQLLNFFNIDDKMRFVDVPGYGYARVSKKEREKWGCMIEEYL
                     TTRENLRAVVSLVDLRHDPSADDVQMYEFLKYYEIPVIIVATKADKIPRGKWNKHESA
                     IKKKLNFDPSDDFILFSSVSKAGMDEAWDAILEKL"
     gene            12811..13191
                     /locus_tag="VQU30_000768"
     CDS             12811..13191
                     /locus_tag="VQU30_000768"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001140413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RidA family protein"
                     /protein_id="HET2446907.1"
                     /translation="MAKTIHTDKAPKAIGPYVQGKIVGNLLFASGQVPLSPETGEIVG
                     ENIQEQTEQVLKNIGAILAEAGTDFDHVVKTTCFLSDMNDFVPFNEVYQTAFKEEFPA
                     RSAVEVARLPRDVKVEIEVIAEIG"
     gene            13243..14133
                     /gene="rapZ"
                     /locus_tag="VQU30_000769"
     CDS             13243..14133
                     /gene="rapZ"
                     /locus_tag="VQU30_000769"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000163059.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNase adapter RapZ"
                     /protein_id="HET2446908.1"
                     /translation="MTKKQLHLVIVTGMSGAGKTVAIQSFEDLGYFTIDNMPPALLPK
                     FLQLVEIKEDNPKLALVVDMRSRSFFSEIQAVLDELENQDGLDFKILFLDAADKELVA
                     RYKETRRSHPLAADGRILDGIKLERELLAPLKNMSQNVVDTTELTPRELRKTLAEQFS
                     DQEQAQSFRIEVMSFGFKYGIPIDADLVFDVRFLPNPYYLPELRNQTGVDEPVYDYVM
                     NHPESEDFYQHLLALIEPILPSYQKEGKSVLTIAMGCTGGQHRSVAFAKRLAQDLSKN
                     WSVNEGHRDKDRRKETVNRS"
     gene            14130..15107
                     /locus_tag="VQU30_000770"
     CDS             14130..15107
                     /locus_tag="VQU30_000770"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399181.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YvcK family protein"
                     /protein_id="HET2446909.1"
                     /translation="MRKPKITVIGGGTGIPVILKSLREKDVEIAAIVTVADDGGSSGE
                     LRKNMQQLTPPGDLRNVLVAMSDMPKFYEKVFQYRFSEDAGAFAGHPLGNLIIAGLSE
                     MQGSTYNAMQLLSKFFHTTGKIYPSSDHPLTLHAVFQDGTEVAGESHIVDHRGIIDNV
                     YVTNALNDDTPLASRRVVQTILESDMIVLGPGSLFTSILPNIVIKEIGRALLETKAEI
                     AYVCNIMTQRGETEHFTDSDHVEVLHRHLGRPFIDTVLVNIEKVPQEYMNSNRFDEYL
                     VQVEHDFVGLCKQVSRVISSNFLRLENGGAFHDGDLIVDELMRIIQVKK"
     gene            15104..16015
                     /gene="whiA"
                     /locus_tag="VQU30_000771"
     CDS             15104..16015
                     /gene="whiA"
                     /locus_tag="VQU30_000771"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004257845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein WhiA"
                     /protein_id="HET2446910.1"
                     /translation="MSFTVAVKEEILGQHHLSRHELSAIIKMSGSIGLSTSGLTLSVV
                     TENAKLARHLYESFLHFYEIKSEIRHHQRSNLRKNRVYTVFTDEKVQDLLSDLHLADS
                     FFGLETGIDEAILSDEEAGRAYLCGAFLVNGSIRDPESGKYQLEISSVYLDHAQGIAS
                     LLQQFLLDAKVLERKKGAVTYLQRAEDIMDFLIVIGAMQARDDFERVKILRETRNDLN
                     RANNAETANIARTVSASMKTINNISKIKDIMGLENLPVDLQEVAQLRIQHPDYSIQQL
                     ADSLSTPLTKSGVNHRLRKINKIADEL"
     gene            complement(16049..17017)
                     /locus_tag="VQU30_000772"
     CDS             complement(16049..17017)
                     /locus_tag="VQU30_000772"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000081018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HET2446911.1"
                     /translation="MSQLYDITIVGGGPVGLFAAFYAHLRQAKVQIIDSLPQLGGQPA
                     ILYPEKEILDVPGFPNLTGEELTNRLIEQLNGFDTPIHLNETVLEIDKQEEEFAITTS
                     KGSHLTKTVIIAMGGGAFKPRPLELEGVEGYENIHYHVSNIQQYAGKKVTILGGGDSA
                     VDWTLAFEKIAPTTLVHRRDNFRALEHSVQALQESSVTIKTPFAPSQLLGNGKTLDKL
                     EITKVKSDETETIDLDHLFVNYGFKSSVGNLKNWGLDLNRHKIIVNSKQESSQAGIYA
                     IGDCCYYDGKIDLIATGLGEAPTAVNNAINYIDPEQKVQPKHSTSL"
     gene            17153..18010
                     /locus_tag="VQU30_000773"
     CDS             17153..18010
                     /locus_tag="VQU30_000773"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001867651.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR00159 family protein"
                     /protein_id="HET2446912.1"
                     /translation="MNFQQLSNLQYWTSLFASPWTIAINLIDILIVAYILYHFTKAIA
                     GTKIMILVRGVLVFILAQILANMIGLTTISWLINQIITYGVIAAVVIFSPEIRTGLER
                     LGRATDFFSNAPISAEEQMIRAFVKSVEYMSPRKIGALVAIQRVRTLQEYISTGIPLD
                     AKISAELLINIFIPNTPLHDGAVIIKEERIAVTSAYLPLTKNTGISKEFGTRHRAAIG
                     LSEVSDALTFVVSEETGGISITYNGRFKHNLTLDEFETELREILLPKEEVGLSFKERL
                     LGGWKHEKK"
     gene            17997..18776
                     /locus_tag="VQU30_000774"
     CDS             17997..18776
                     /locus_tag="VQU30_000774"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397683.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YbbR-like domain-containing protein"
                     /protein_id="HET2446913.1"
                     /translation="MKKNSLYIISSLFFACVLFVYATATNFQNSTSARQVKTETYTNT
                     VTNVPIDIRYNSDKYFISGFASEVSVVLTGANRLSLASEMQESTRKFKVTADLTDAGV
                     GTIEVPLSIEDLPNGLTAVATPQKITVKIGKKAQKDKVKIVPEIDPSQIDSRVQIENV
                     MVSDKEVSITSDQETLDRIDKIIAVLPTSERITGNYSGSVPLQAIDRNGVVLPAVITP
                     FDTIMKVTTKPVAPSSSTSNSSTSSSSETSSSTKATSSKTN"
     gene            18800..20152
                     /locus_tag="VQU30_000775"
     CDS             18800..20152
                     /locus_tag="VQU30_000775"
                     /EC_number="5.4.2.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglucosamine mutase"
                     /protein_id="HET2446914.1"
                     /translation="MGKYFGTDGVRGEANLELTPELAFKLGRFGGYVLSQHETEAPKV
                     FVGRDTRISGEMLESALVAGLLSVGIHVYKLGVLATPAVAYLVETEGASAGVMISASH
                     NPALDNGIKFFGGDGFKLDDEKEAEIEALLDAEEDTLPRPSAEGLGILVDYPEGLRKY
                     EGYLVSTGTPLDGMKVALDTANGAASTSARQIFADLGAQLTVIGETPDGLNINLNVGS
                     THPEALQEVVKESGSAIGLAFDGDSDRLIAVDENGDIVDGDKIMYIIGKYLSEKGQLA
                     QNTIVTTVMSNLGFHKALNREGINKAVTAVGDRYVVEEMRKSGYNLGGEQSGHVILMD
                     YNTTGDGQLSAIQLTKIMKETGKSLSELAAEVTIYPQKLVNIRVENVMKEKAMEVPAI
                     KAIIEKMEEEMAGNGRILVRPSGTEPLLRVMAEAPTTEEVDYYVDTITDVVRAEIGID
                     "
     gene            20226..20600
                     /locus_tag="VQU30_000776"
     CDS             20226..20600
                     /locus_tag="VQU30_000776"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001050081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1149 family protein"
                     /protein_id="HET2446915.1"
                     /translation="MNLKREQEFVSQYHFDARNFEWENENGAPETKVDVNFQLLQHDQ
                     ENQVTSLIVILSFMIVFDKFVISGTISQVNHIDGRIVNEPSELNQEEVETLARPCLNM
                     LNRLTYEVTEIALDLPGINLEF"
     gene            20602..21450
                     /locus_tag="VQU30_000777"
     CDS             20602..21450
                     /locus_tag="VQU30_000777"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000762171.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HET2446916.1"
                     /translation="MKLAVFTDSSAYLSEETLQREDLFVLDIPVNIDGEEYVEGINLS
                     AEEFYQKMAQASELPKTSQPSIAKLDEILTSLKEQGYTHALGLFLSSGISGFYQNIQY
                     MVDDYEGLTIAFPDTLITSAPLGIMVESVFNWRDQGDDFASIQDKLAIQISRTSAFIM
                     VDDLDHLVKGGRLSNGAAILGNLLSIKPILYFNDQGVIEVYEKVRTEKKATKRLIEII
                     KETTASGQYRVIVIHGNAPEKAEELRQHLLDFGLGSDVSLATFGSVIGTHLGAGSIAL
                     GYIPVI"
     gene            21727..22494
                     /locus_tag="VQU30_000778"
     CDS             21727..22494
                     /locus_tag="VQU30_000778"
                     /EC_number="1.17.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002897644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxy-tetrahydrodipicolinate reductase"
                     /protein_id="HET2446917.1"
                     /translation="MSIRVIIAGFKGKMGQAACQMVLTDPDLDLVAVLDPFESESEWQ
                     GIPVFKDKADLAGFEADVWVDFTTPAVAYENTRFALENGFAPVVGTTGFTSEEIAELK
                     EFSRAQDLGGLIAPNFALGAVLLMQFATQAAKYFPNVEIIELHHDKKKDAPSGTAIKT
                     AELMAEVRESIQQGAADEEELIAGARGADFDDMRIHSVRLPGLVAHQEVIFGNQGEGL
                     TLRHDSYDRISFMTGVNLGIKEVVKRHELVYGLEHLL"
     gene            22506..23690
                     /locus_tag="VQU30_000779"
     CDS             22506..23690
                     /locus_tag="VQU30_000779"
                     /EC_number="2.7.7.72"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001138849.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CCA tRNA nucleotidyltransferase"
                     /protein_id="HET2446918.1"
                     /translation="MPSEFQKALPVLEKIKEAGFEAYFVGGSVRDALLHSPIHDVDIA
                     TSSYPEETKQIFPRTADIGIEHGTVLVLDGDEEYEVTTFRTEDVYVDYRRPSAVSFVR
                     SLEEDLKRRDFTVNAFALDETGEIVDLFHGLEDLEKQVLRAVGVASERFNEDALRIMR
                     GFRFQASLGFALEPETFKAMKTLTPLLEKISVERTFVEFDKLLLAPFWRRGLASMIES
                     QAYDYLPDMASSQDKLNRLFDLETDFTFESSEQAWAALLWALEIENAQSFLKSWKTSR
                     QFAKQVQDLLIILALRENGELSKRDCYRFDIDLLLQAENLRQAQGKEVNPQAITEKYQ
                     SLTIHDKKEIQINGDILIKEYGYQPGPDLGEILTEIEFAIVDGELENNREAIHAYLRE
                     KK"
     gene            23687..25558
                     /locus_tag="VQU30_000780"
     CDS             23687..25558
                     /locus_tag="VQU30_000780"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001279112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HET2446919.1"
                     /translation="MSDFIVEKLSKSVGDKTVFRDISFIIHDLDRIGLIGVNGTGKTT
                     LLDVLSGVSGFDGDVSPFSAKNDYQIGYLTQDPDFDDRKTVLDTVLSSELKEIQLIRE
                     YELIMLDYSEDKQARLERVMAEMDSLQAWEIESQVKTVLSKLGIQDLSTPVGELSGGL
                     RRRVQLAQVLLGNHDLLLLDEPTNHLDIAIIEWLTLFLKNSKKTVLFITHDRYFLDAL
                     STRIFELDRAGLTEYQGNYQDYVRLKAEQDERDAALLHKKEQLYKQELAWMRRQPQAR
                     ATKQQARINRFHDLKKEVSGSSAETDLTMNFETSRIGKKVIEFQAVSFAYENKPILQD
                     FNLLVQAKDRIGIVGDNGVGKSTLLNLIAGSLEPTKGQVVIGETVRIAYFSQQIEGLD
                     ESKRVINYLQEVAEEVKTSGGSTTSIAELLEQFLFPRSTHGTLIEKLSGGEKKRLYLL
                     KLLLEKPNVLLLDEPTNDLDIATLTVLENFLQGFAGPVLTVSHDRYFLDKVATKILAF
                     EDSKIRPFFGHYTDYLDEKAFETDMANQVQKVEKEKVVKVREDKKRMTYQEKQEWASI
                     EGDIETLEKRIAAIEEEMQANGSDFGKLATLQKELDEKNEALLEKYERYEYLSEFDS"
     gene            complement(25701..26885)
                     /gene="mntE"
                     /locus_tag="VQU30_000781"
     CDS             complement(25701..26885)
                     /gene="mntE"
                     /locus_tag="VQU30_000781"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000813920.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CDF family manganese efflux transporter MntE"
                     /protein_id="HET2446920.1"
                     /translation="MKQSISNLKLAERGAIISISTYLILSAAKLAAGHLLHSSSLVAD
                     GFNNVSDIIGNVALLIGIRMARQPADRDHRFGHWKIEDLASLITSIIMFYVGFDVLRD
                     TIQKILSREETVIDPLGATLGIISAAIMFVVYLYNTRLSKKSNSKALKAAAKDNLSDA
                     VTSLGTAIAILASSFNYPIVDKLVAIIITFFILKTAYDIFIESSFSLSDGFDDRLLED
                     YQKAIMEIPKISKVKSQRGRTYGSNIYLDITLEMNPDLSVFESHEIADQVESMLEERF
                     GVFDTDVHIEPAPISEDEILDNVYKKLLMREQLIDQGNQLEELLTDDFVYIRQDGEQM
                     DKEAYKTKKELNSAIKDIQITSISQKTKLICYELDGIIHTSIWRRHETWQNIFHQETK
                     KE"
     gene            27189..29885
                     /locus_tag="VQU30_000782"
     CDS             27189..29885
                     /locus_tag="VQU30_000782"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000032417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation-translocating P-type ATPase"
                     /protein_id="HET2446921.1"
                     /translation="MSKEQKRQAFYTQSPEEVLQAVDATEQGLSSSEAEKRLAEFGHN
                     ELEEGEKRSILVKFIEQFKDLMIIILVAAAILSVVTSGGEDIADAIIILAVVIINAAF
                     GVYQEGKAEEAIEALKSMSSPVARVLRDGHMAEIDSKELVPGDIVALEAGDVVPADLR
                     LIEANSLKIEEAALTGESVPVEKDLSVELATDAGIGDRVNMAFQNSNVTYGRGMGVVV
                     NTGMYTEVGHIAGMLQDADETDTPLKQNLNNLSKVLTYAILVIALVTFVVGVFIQGKN
                     PLGELLTSVALAVAAIPEGLPAIVTIVLSLGTQVLAKRHSIVRKLPAVETLGSTEIIA
                     SDKTGTLTMNKMTVEKVFYDAVLHDSADDIELGLEMPLLRSVVLANDTKIDVEGNLIG
                     DPTETAFIQYALDKGYDVKGFLEKYPRVAELPFDSDRKLMSTVHPLPDGRFLVAVKGA
                     PDQLLKRCLLRDKAGDIAPIDEKVTNLIHTNNSEMAHQALRVLAGAYKIIDSIPENLT
                     SEELENDLIFTGLIGMIDPERPEAAEAVRVAKEAGIRPIMITGDHQDTAEAIAKRLGI
                     IDANDTEGHVLTGAELNELSDEEFEKVVGQYSVYARVSPEHKVRIVKAWQKQGKVVAM
                     TGDGVNDAPALKTADIGIGMGITGTEVSKGASDMILADDNFATIIVAVEEGRKVFSNI
                     QKTIQYLLSANTAEVLTIFLSTLFGWDVLQPVHLLWINLVTDTFPAIALGVEPAEPGV
                     MNHKPRGRKASFFSGGVLSSIIYQGVLQAALVMSVYGLAIAYPVHVGDNHAIHADALT
                     MAFATLGLIQLFHAYNVKSVYQSILTVGPFKSKTFNWSILVSFILLMATIVVEPLEGI
                     FHVTKLDLSQWGIVMAGSFSMIIIVEIVKFIQRKLGFDKNAI"
     gene            29898..30689
                     /gene="yghU"
                     /locus_tag="VQU30_000783"
     CDS             29898..30689
                     /gene="yghU"
                     /locus_tag="VQU30_000783"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001277405.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione-dependent disulfide-bond
                     oxidoreductase"
                     /protein_id="HET2446922.1"
                     /translation="MSAYQLPTVWQDEASNQGAFTGLNRPTAGARFEQNLPKGEQAFQ
                     LYSLGTPNGVKVTILLEELLEAGFKEAAYDLYKIAIMDGDQFGSDFVKLNPNSKIPAL
                     LDQSGTENVRVFESAHILLYLAEKFGAFLPSNPVEKVEVLNWLFWQAGAAPFLGGGFG
                     HFFNYAPEKLEYPINRFTMEVKRQLDLLDKELAQKPYIAGNDYTIADIAIWSWYGQLV
                     QGNLYQGSAKFLDASSYQNLVKWAEKIANRPAVKRGLEVTYTEIK"
     gene            30805..31215
                     /locus_tag="VQU30_000784"
     CDS             30805..31215
                     /locus_tag="VQU30_000784"
                     /EC_number="3.5.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000412213.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide deformylase"
                     /protein_id="HET2446923.1"
                     /translation="MEKKIVKDILFLSQVSHPASQEDLYLARDLQDTLLANRDTCVGL
                     AANMIGMQKRVIIFNLGLVPVVMFNPVLLSFEGSYEAEEGCLSLVGVRSTKRYETIRL
                     AYRDSKWQEQTITLTGFPAQICQHELDHLEGRII"
     gene            31227..32822
                     /locus_tag="VQU30_000785"
     CDS             31227..32822
                     /locus_tag="VQU30_000785"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000822862.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2446924.1"
                     /translation="MKRIVFELIFIATTWYIFLPPLNLTSWEFLFFLCGHLLVVAILF
                     GFGKGINLVKTVHVRHGKAEAALNLEGFKINRLGKILLASIGGILLLAALVSLVTSSM
                     FQAKNYANVVTVTEKDFTEFPKSDTSKVPILDRSTAEKIGDRYLGSLTDKVSQYVAAD
                     TYTQLTIDGKPYRVTPLEYADPIKWFNNQAKGIGEYIKVDMVTGNADLVDLKTPIKYS
                     DSEYFNRDVKRHLRLKYPTKIFKTPSFEVDDEGNPFYVATVYQKQFGLAVPRPASVII
                     LDATNGETKEYSLSDVPEWVDRIYPAEETIEQINYNGKYKDGFLNAMISKKNVTQTTN
                     GYNYLSIGNDIYLYTGVTSANADESNLGFILENMRTGEITKYSLASATEESARESAEG
                     AVQEKSYKATFPILINLNDKPLYIMGLKDNAGLVKEYALVDAVEYQNVIVATTVEEML
                     SKYANKNDLEIDNATTESIKGVVADLKSAVIKGDTVYFFKVDGKIYKVKASVSDDLPY
                     LENGKTFEGQVGKDNYLKTFKVQ"
     gene            32989..33153
                     /locus_tag="VQU30_000786"
     CDS             32989..33153
                     /locus_tag="VQU30_000786"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000508323.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YczI family protein"
                     /protein_id="HET2446925.1"
                     /translation="MGFYLMVASMLLGLLALKIGFSQFKEKKDKFLSILTSLAGTALV
                     LVAVWLGWPK"
     gene            33232..33960
                     /gene="yaaA"
                     /locus_tag="VQU30_000787"
     CDS             33232..33960
                     /gene="yaaA"
                     /locus_tag="VQU30_000787"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000697769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peroxide stress protein YaaA"
                     /protein_id="HET2446926.1"
                     /translation="MKILIPTAKEMNTDLPSIEAIPLKPESQTVLDALALYSASQLES
                     FYKVSAEKAAEEFQNIQALKRQTAQHYPALKLFDGLMYRNIKRDKLTEAEQDYLENHV
                     FITSALYGVVPALSPMAPHRLDFLMKLKVAGKTLKSHWKAVYDEALKKEEVIFSLLSS
                     EFETVFSKEIRAKMVTFKFMEDRGGQLKIHSTISKKARGAFLTALIENQVQTVGEARR
                     LNFAGFVYREDLSQPQGLVFVKEV"
     gene            complement(34011..35495)
                     /locus_tag="VQU30_000788"
     CDS             complement(34011..35495)
                     /locus_tag="VQU30_000788"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003096885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HET2446927.1"
                     /translation="MRNLLSTKVQRQLRLMETLIQNRNWMKLHELAEKLGCTERILKS
                     DLNELRIAFPSINIQSSVNGIMIDLEVNTSVEDIYQYFLANSQSFQLLEYMFFNEGLP
                     IYRTIENLYFSSANLYRLGRNITKVLSSQFQIELSFTPSEIRGNEIDIRYFFAQYFSE
                     RYYFLDWPFPDLPEEDLTEFADFFYKITNYPMRFSIYRMYKLMIAISIHRVKNGHFID
                     LPNHFYKEYYPLLKSIPNFQETLAYFSKHFGLEMTPDTIAQIFISFLQNDIFLDPQEF
                     FNSLEDNSQARYSYQLLSQILERLSKQYKITFTNHDELIWHLHNTAFFERQEIFSTPI
                     LFEQKALTIKKFEGYFPDFMGSARQELAQYRQAIGQHDHPEQLEHLMYTILTHAENLS
                     TQLLENRPPIKVLIISNFDHAISLTFVDMLSYYCNNRFTFDIWDELKTSPEILNQTDY
                     DIIVSNFYISGITKKFICRNHLSIMNLVNHLNTLSNEIHLSNTL"
     gene            35711..>37669
                     /locus_tag="VQU30_000789"
     CDS             35711..>37669
                     /locus_tag="VQU30_000789"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001816486.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="G5 domain-containing protein"
                     /protein_id="HET2446928.1"
                     /translation="MKHSHKKSFDWYSMQQRYSIRKYYFGAVSVLLGTALVLGAAASV
                     QTVQAEENKQETTNSISVGRGEAATKPAEVSASNKEKTYAAPTVANPVETTPVKTGEV
                     TKPAEKVEEAKDKKEEVTHQDAIDKSKLLTALSRAKKLESKLYTEASAANLQTSIQAG
                     QSLLGKADASEAELSAAESSIQSSIIGLELRSNSNKGTVSETPVAKKANIVEAKEETN
                     PAATTDRSAVDSAVLPTSTAAKVETTSAPASINEILKPGLSLSDARQNPAIRKEDVDR
                     GYSGFRAAPAPTNQPVTNLGNNTVFTDISRGSHTFRGNGNSRRGNPIHFDVTTTRVRN
                     RVDFSIRYSGPGEFVNNNFILDKGNGFGEPSRATVSTPKLRDQVKNISKGGNFVSHSG
                     YSLEAAVETSTNQTIKFSLPIANPNGDLSVRLRPVTFNVGQGESGSATSNDPYSNSNY
                     YFREKPLLLDANPNGGTNNKTVSEDIDFQTVYLPTSKLPEGQTRLVREGEKGQRQIIY
                     KVHQLGNETILGLPISNSVIKEVKPRIMQIGVAKDLIDTVKPRVDQNKVGDTNNLTFY
                     LDNDGNGVYTEGVDELVQKIAIKDGAKGEKGDRGERGLTGAQGAKGEKGDRGERGLTG
                     AQGAKGEKGDRGERGLTGAQGAKGEKGDR"
BASE COUNT        11318 a         6899 c         8567 g        10885 t
ORIGIN      
        1 tttaattaaa ttgtaagtca atgcaagtca ataaggaatt ttcagataat tattgaaaaa
       61 gagacgtttt tatgttataa tgatagcgat taaattcgag gtgaaaaatg gcacatttat
      121 tagaaaaaac tagaaaaatt acatcaattt tgaaacgctc agaggagcag ttgcaggatg
      181 agctccctta caacgctatt acgcgtcagt tagcggatat tattcattgc aatgcctgca
      241 ttatcaatag taagggacgt ctgcttggct attttatgcg ttataaaaca aatacagatc
      301 gcgtagagca attcttccaa actaagattt tcccagatga ctacgttcaa ggggctaata
      361 tgatttacga aacagaagca aacttgcctg ttgagcatga tatgagtatt ttccctgttg
      421 agagtagaga tgattttcca gatggcttga cgactattgc accgattcat gtatcgggga
      481 ttcgccttgg ttctttgatt atttggcgta atgataaaaa attcgaagat gaggacttgg
      541 ttcttgttga gattgccagt accgttgttg ggattcagct tcttaacttc caacgtgaag
      601 aagatgagaa aaatattcgt cgtcgtactg ctgtcaccat ggcggtcaat accctttctt
      661 actccgaact ccgtgctgtt tcagcaattt taggggaatt aaatggaaat gaagggaagt
      721 tgactgcgtc agtgattgca gatcgtatcg gaatcactcg ctctgtgatt gtcaatgctc
      781 ttcgtaaact tgagtctgcg gggattattg aaagtcgctc acttggaatg aagggaacct
      841 atcttaaggt cttgatttca gatatttttg aagaagtgaa gaaaagagat tactaatgac
      901 aaaggcttta atttcgattg attatacaga agattttgtt gctgatagtg ggaagctgac
      961 agcaggtgct ccagctcagg cgatttcgga tgccatcagc aaggtaactc gattagcttt
     1021 tgaacgagga gattatatct tctttactat tgatgctcat gaagaaaacg attttttcca
     1081 tccggaaagt aagttatttc ctcctcataa tctgattggg acgagtggac ggaatttata
     1141 tggagatttg gggatctttt atcaagagca tggttcagac agtcgtgtct tttggatgga
     1201 taaacgccat tactcagctt tttcagggac tgacctagat attcgtttga gagagcgtag
     1261 agtgtctacc gttatcttaa caggtgtctt gacggatatc tgtgtcctac atacagctat
     1321 agatgcctat aatctaggat atgacatcga gattgttaaa ccagctgttg cttccatctg
     1381 gcctgaaaat catcaatttg ccctaggtca tttcaaaaat acactcggag ctaagttagt
     1441 agatgaaaat ctaaatgaac tttctgagta acctggttgg tgaaaatgaa aaaatttgaa
     1501 aaaaagtgtt gacaagcatc ccaaaagttg atatactagt aaagtaatcg atgcggggat
     1561 ggcggaattg gcagacgcgc aggactaagg atcctgtgac cgctttaggt cgtgagggtt
     1621 caagtccctc tctccgcata ggaaaagagt tagctaaagc tagctctttt gtatttctct
     1681 aaaaaattag aatccagtca aatgtagtgg agaatcagcg aaaatatggg aaaactgttc
     1741 cttgtttctg cttttgtcat agaagaataa taaagattat cttcttcaaa ttctccgata
     1801 ttctctaaag ttttgtgcaa gttgcacaga acttttttat ttttttggtc atcttgccat
     1861 agaaatataa agcgttttca tctataatat aattatcaaa agacaaaagg agttcacctc
     1921 atggtagaat tgaatcttaa aaatatttac aaaaaatatc caaacagcga acactattca
     1981 gttgaagatt tcaacttgaa catcaaagat aaagaattta tcgttttcgt aggaccttca
     2041 ggatgtggta aatcaactac actccgtatg attgctggtc ttgaagacat tacagaaggt
     2101 actgcatcta tcgatggcgt ggttgtcaac gacgtagctc caaaagaccg tgatatcgcc
     2161 atggtattcc aaaactacgc tctttaccca cacatgactg tttatgacaa catggctttc
     2221 ggtttgaaat tgcgtaaata cagcaaagaa gacattaaca aacgtgttca agaagcagct
     2281 gaaatacttg gattgaaaga attcttggaa cgtaaaccag ctgacctttc aggtggtcaa
     2341 cgtcaacgtg ttgccatggg gcgtgcgatt gtccgtgatg cgaaagtatt cttgatggac
     2401 gaacctttgt caaacttgga tgccaaactt cgtgtatcaa tgcgtgctga aatcgctaaa
     2461 attcaccgtc gtatcggagc tacaactatc tatgtaactc acgaccaaac agaagcgatg
     2521 acacttgcag accgtatcgt tattatgtca gctactaaga accctgctgg tacaggtact
     2581 atcggacgtg tagaacaaat cggtactcct caagaagttt acaaaaatcc agttaacaaa
     2641 ttcgttgcag gattcatcgg aagcccagct atgaacttca tcaacgtgaa attggttggt
     2701 agcgaaattg tttctgacgg tttccgtttg aaagtgccag aaggagcatt gaaagttctt
     2761 cgtgaaaaag gctacgaagg aaaagaattg atctttggta tccgtccaga agacgtgaat
     2821 gcagaacctg ctttccttga aacattccca gactgtgttg taaaagcgac tatctctgta
     2881 tcagaactgc ttggttcaga atctcacctt tactgccaag ttggtaaaga cgagtttgtt
     2941 gcaaaagttg atgctcgtga ctacttgcaa acaggtgcaa cagttgagct tggatttgac
     3001 ttgaacaaag cacacttctt cgatgtagaa actgaaaaaa caatctacta aaataaataa
     3061 aattcaaagc actacaagaa aagatatctc tttatcaatt gtagtggaga gatatcagtt
     3121 aatctaggga gagaaacaaa atgcttctct cctttttgct agggaagtca tattatgcat
     3181 ctatattgtg atgctcttta atactcttcg aaaatctctt caaaccacgt caacgtcgcc
     3241 ttgccgtacg tatgattact gatttcgtca gttttatctg caacctcaaa gatgtacttt
     3301 gagcagctta cggctagttt cctagtttgc tctttgattt ccattgagta ttatttgtgg
     3361 gtaccatcta caagtgaagc tatatgcgta aactacgtga gcaattgaat tcgaactaga
     3421 gaggtaataa taaatttatg ctatagttat ggtgacttgt atgcttttga ttctagttta
     3481 tcaaataata gattagaatt gtcagataat atcattttgt gttataatga agaaaaaaca
     3541 gaggtgttca aatgtcagaa gcaggtcata agtttttagc aaaattgggg aaaaaacgct
     3601 tacgtccagg tggaaagcgt gctacagatt ggttaattgc agaaggagga ttgtcaaaag
     3661 aaaagagaat actagaggtt gcgtgtaata ggggaactac agcaattgag ttggcacagc
     3721 gttttggttg caagataact gctgttgata tggatgctca agctttagaa gtggctaaaa
     3781 aatctgctgg aacggcaggt gttgctcatt taatcagttt tgaaagagca aatgcaatga
     3841 aacttcctta tcaagatgct agttttgata ttgttataaa tgaagctatg ctgactatgc
     3901 aagccgatca agctaagaaa aaatgtgtaa tggaatatct aagggtatta aaacctggag
     3961 gtcttctttt gacacatgat gtgcttctta aggaagctaa agagtctatc agacaggaat
     4021 tatcacaagc aattcatgta aatgtaggtc ctttaactca agatggttgg gaacaggtga
     4081 tgatagaatc aggttattgt gatgtgaaag tattgactgg tgaaatgaca ttaatgaaat
     4141 tatcgggtat gatttatgac gaaggttggc taggaacttt gaaaatttgt gtaaatgctt
     4201 gtaaaaagga gaatagaaag cagtttttaa ctatgtataa aatgtttgct aagaataaac
     4261 agaaattggg ctttattgcg atggctagtt ataaatcgtc aaaacgttag ataattattg
     4321 aagttaactt ttcctttttt ctttcttaaa aaatatgcta taatagagag tgaaaaactt
     4381 tgaaagaaag aaaaagatga atttaaaaga ttacattgca acaattgaaa attatccaaa
     4441 ggaaggcatt accttccgtg atattagtcc tttgatggct gatggaaatg cttatagcta
     4501 cgctgttcgt gaaatcgttc agtatgctac tgacaagaaa gtcgacatga tcgtgggacc
     4561 tgaagctcgt ggatttatcg tgggttgtcc agttgccttt gagttgggaa ttggttttgc
     4621 gcctgttcgt aagccaggta aattgccacg cgaagttatt tctgctgact atgaaaaaga
     4681 gtacggtgtc gataccttga ctatgcacgc ggatgccatt aagccaggtc aacgtgttct
     4741 tattgtagat gaccttttgg cgacaggtgg aactgttaag gcaactatcg agatgattga
     4801 aaaacttggt ggtgttatgg caggttgtgc cttccttgtt gaattggatg aattgaacgg
     4861 ccgtgaaaaa atcggtgact acgactacaa agttcttatg cattattaat gaaaacagtc
     4921 cctagggctg ttttctctac actaggatat aaaaatagac tataactagt tagagaaaaa
     4981 ctataattga aaactatatc ttcttgcagt ataataaaag gactaagtgt ttgagatttg
     5041 tcttcaaaca catgcaatta ttcctgagag agtacagtta ggagagggtt atgccgattc
     5101 gaattgataa aaaattgcca gctgttgaga ttttacggac agagaatatc tttgtcatgg
     5161 atgatcaacg tgctgcccac caagatatcc gtcctttgaa gattttaatt ttaaatctca
     5221 tgccacagaa aatggtcaca gagacccagt tgttgcgtca cttggctaat acacccctac
     5281 aactggatat tgattttctc tatatggaga gccaccgttc taaaacaact cgttcagagc
     5341 acatggagac cttctataaa acttttcctg aagtcaagga tgagtatttt gatgggatga
     5401 tcatcacggg tgctccagtt gagcatttac catttgagga agtggactat tgggaggaat
     5461 ttaggcagat gcttgagtgg tctaagacac atgtctattc gacccttcat atctgttggg
     5521 gggctcaggc tgggctttat ctgcgctatg gtgtagaaaa ataccagatg gacagtaagc
     5581 tatcaggtat ttatcctcag gacaccctaa aagagggtca ccttctattt agaggctttg
     5641 atgatagcta tgtatcccct cattcacggc acacggagat ttctaaggaa gaggtcttaa
     5701 acaagaccaa tctcgagatt ttatcagaag gacctcaggt tggggtttct attttggcca
     5761 gtcgtgattt acgagaaatt tatagttttg gtcatttgga gtatgaccgt gataccttgg
     5821 caaaagagta ttttcgagat cgtgatgcag gtttcgaccc acatattcca gaaaattact
     5881 ttaaagatga tgatgttaat caggtacctt gtctttgttg gtcttcatct gcagccctct
     5941 ttttcagtaa ttgggtaaac catgcggtct atcaggagac gccttttgat tggagaaaga
     6001 tagaagatga tgcatctgca tatgggtatt tataagagga attatgacat atttagacgc
     6061 ttttaaatca ggtaccttgg ttttaccgag tgccctgctc ttgcatttta aggaactctt
     6121 tccttctagc gacgattttc tggtttggca atttttctat ttgcaaaata cgacaggctt
     6181 agaagaaatg tcgccaagcc agattgctga aaggattggc aaggaaattt cggatgtcaa
     6241 ccagtccatt tctaatctga cggaaagggg actgctccag tatcgtacta tcgaattaaa
     6301 tggcgaaatt gaattgctct ttgatgctag tttggccttg gaacgtttgg atgacctgtt
     6361 tggagcagtt cgttcaagtt cagaccagct aacacctcaa aaccagctca aggatttggt
     6421 ggaaaccttc cagcaggagt tgggacgatt gttgacgcct tttgagattg aggatttgac
     6481 caagacacta aaggaagatg gaaccagtgc tgacttgatt aaggaggctc ttcgtgaagc
     6541 tgttttgaat ggaaaaccaa actggaagta cattcaggcg attttgagaa actggcgcca
     6601 tgaaggaatc aagagtgtgg ctcaaattga ggccaagaga gcagaaagag aagcaagcaa
     6661 tcctcagttg acacaggtat ctgcagattt cagaaatgcc atggatctct ggaaggatta
     6721 atccatgcaa gtaggcttga aatccgagta agatttgcaa gctgtgtata attgtgatag
     6781 aataaataga aaataaattg aaaaaagagg tatgtgaaat gtcacgtaaa ccatttatcg
     6841 ctggtaactg gaaaatgaac aaaaatccag aagaagctaa agcattcgtt gaagcagttg
     6901 catcaaaact tccttcatca gatcttgttg aagcaggtat cgctgctcca gctcttgatt
     6961 tgacaactgt tcttgctgtt gcaaaaggct caaaccttaa agttgctgct caaaactgct
     7021 actttgaaaa tgcaggtgct ttcactggtg aaactagccc acaagttttg aaagaaatcg
     7081 gtactgatta cgttgttatc ggtcactcag aacgccgtga ctacttccat gaaactgacg
     7141 aagatatcaa caaaaaagca aaagcaatct ttgcgaacgg tatgcttcca atcatctgtt
     7201 gtggtgaatc acttgaaact tacgaagctg gtaaagctgc tgaattcgta ggtgctcaag
     7261 tatctgctgc attggctgga ttgactgctg aacaagttgc tgcctcagtt atcgcttatg
     7321 agccaatctg ggctatcggt actggtaaat cagcttcaca agacgatgca caaaaaatgt
     7381 gtaaagttgt tcgtgacgtt gtagctgctg actttggtca agaagtcgca gacaaagttc
     7441 gtgttcaata cggtggttct gttaaacctg aaaatgttgc ttcatacatg gcttgcccag
     7501 acgttgacgg tgcccttgta ggtggtgcgt cacttgaagc tgaaagcttc ttggctttgc
     7561 ttgactttgt aaaataatca gtaagtagca aaagctaggt ggaacagcat tcagatgtct
     7621 gttacatttt ttataggaga ggaaagattg aaaacaaaaa ttggattagc aagtatctgt
     7681 ttactaggct tggcaactag tcatgtcgct gcaaatgaaa ctgaagtagc aaaaacttcg
     7741 caggatacaa cgacagcttc aagtagttca gagcaaaatc agtcttctaa taaaacgcaa
     7801 acgagcacag aagtacagac taatgctgct gcccactggg atggggatta ttatgtaaag
     7861 gatgatggct ctaaagctca aagtgaatgg atttttgaca actactataa ggcctggttt
     7921 tatattaatt cagatggtcg ttactcgcag aatgaatggc atggaaatta ctacctgaaa
     7981 tcaggtggat atatggccca aaacgagtgg atctatgaca gtaattacaa gagttggttt
     8041 tatctcaagt cagatggggc ttatgctcat caagaatggc aattgattgg aaataagtgg
     8101 tactacttca agaagtgggg ttacatggct aaaagccaat ggcaaggaag ttatttcttg
     8161 aatggtcaag gagctatgat gcaaaatgaa tggctctatg atccagccta ttctgcttat
     8221 ttttatctaa aatccgatgg aacttatgct aaccaagagt ggcaaaaagt gggcggaaaa
     8281 tggtactatt tcaagaagtg gggctatatg gctcggaatg agtggcaagg caactactat
     8341 ttgactggaa gtggtgctat ggcgactgac gaagtgatta tggatggtgc tcgctatatc
     8401 tttgcggcct ctggtgagct caaagaaaag aaagatttga atgtcggctg ggttcacaga
     8461 gatggtaaac gctatttctt taataataga gaagaacaag tgggaaccga acatgctaag
     8521 aaaatcattg atattagtga gcacaatggt cgtatcaatg attggaaaaa ggttattgat
     8581 gagaacgagg tggatggtgt cattgttcgt ctaggttata gcggtaaaga agacaaggaa
     8641 ttggcgcata acattaagga gttaaaccgt ctgggaattc cttatggtgt ctatctctat
     8701 acctatgctg aaaatgagac cgatgctgag agtgacgcta aacagaccat tgaacttata
     8761 aagaaataca atatgaacct gtcttaccct atctattatg atgttgagaa ttgggaatat
     8821 gtaaataaga gcaagagagc tccaagtgat acaggcactt gggttaaaat catcaacaag
     8881 tacatggaca cgatgaagca ggcgggttat caaaatgtgt atgtctatag ctatcgtagt
     8941 ttattacaga cgcgtttaaa acacccagat attttaaaac atgtaaactg ggtagcggcc
     9001 tatacgaatg ctttagaatg ggaaaaccct cattattcag gaaaaaaagg ttggcaatat
     9061 acctcttctg aatacatgaa aggaatccaa gggcgcgtag atgtcagcgt ttggtattaa
     9121 gcgatgattt gaaagaggga tgtgatagta gcaccctctt tttctttgtt ttatgatagt
     9181 tcatcctcga gtaaattcaa gttcttgctc ggaaatgaag cttatatagt agattgaata
     9241 tagacaaata ccttgtgatt ggtaaaacat tttagaaatt catttacctt tcctaatcga
     9301 cttggtttca tcttatttca atctattata gtattgggga atttcttcaa accacatcag
     9361 cttggtcagt tctacctgcg acctcaaaac ttgtgctttg gtcaagctgg gtttagtttc
     9421 ctagtttgct gatggatttc cattgactat aagcatccaa ccctcttttt gtcttctaaa
     9481 gaattcttaa attatcagtc tattgcaact tttctcatat aagttctttg tcttgctatt
     9541 ggttttcctt agtagtatac taaggtagta atcattaaga agtggttaca aaaaataatg
     9601 aatgaggtaa agaaaatggt agaattgaaa aaagaagcag taaaagacgt aacatcattg
     9661 acaaaagcag cgccagtagc attggcaaaa acaaaggaag tcttgaacca agctgttgct
     9721 gatttgtatg tagctcacgt tgctttgcac caagtgcact ggtatatgca tggtcgtggt
     9781 ttccttgtat ggcatccaaa aatggatgag tacatggaag ctcttgacgg tcaattggat
     9841 gaaatcagtg aacgcttgat tacactcggt ggaagcccat tctctacatt gacagagttc
     9901 cttcaaaata gtgaaatcga agaagaagct ggtgaatacc gtaatgttga agaaagcttg
     9961 gaacgtgttc ttgttatcta ccgttacttg tcagaacttt tccaaaaagg tttggatgtc
    10021 actgatgaag aaggtgacga tgtgacaaac ggtatctttg caggcgctaa aactgaaaca
    10081 gataaaacaa tttggatgct tgcagccgaa cttggacaag cacctggttt gtaagaaata
    10141 aggaaacata gataaatctg taggaaattt cttacagatt ttttctattt tgtaagctat
    10201 tccaaaccag tctttttttg agttttttga taaaatagta ctatcagtga aaaggatgga
    10261 agcatgacta agaaaatcgt agctatttgg gcccaggatg aagagggtgt gattggtaag
    10321 gaaaatcgtc tgccttggca tttgccagca gaattgcagc actttaaaga aacaactctg
    10381 aatcatgcta tcttgatggg gcgtgtgacc tttgatggga tggggcgtcg cttgcttcca
    10441 aaacgggaaa ccttgatttt gacgcgtaat ccggaagaaa agatagatgg ggttgctact
    10501 tttcaggacg tccagtctgt tcttgactgg tatcaggctc aagaaaagaa tctctacatt
    10561 atcggtggga agcaaatttt tcaggctttt gaaccttacc ttgatgaagt gattgtcact
    10621 cacattcatg ctcgggtgga aggagatacc tatttccctg aagaacttga cttgtctctt
    10681 tttgagacag tttcaagcaa attttacgcc aaagatgaga agaatcctta tgattttacc
    10741 atccaatacc gcaagagaaa ggaagtctaa tggaacggag tttatttggt ctattcacgg
    10801 cttttctgtg tttcatctgc tttctggcag gagcacaagc ttttcgtaaa aagcgttacg
    10861 ggctttctat cctcctttgg ttaaatgcct ttaccaatct ggtcaatagt attcatgctt
    10921 tttacatgac cttattttag atagaatgac agtatagaat ggaaggaaat catgtctaca
    10981 aatagaaaaa atgatatgat ggtttattgc tcattttgtg gcaaaaacca agaagaagta
    11041 caaaaaataa ttgctggcaa caatgctttt atttgtaatg aatgcgtgga gttagctcag
    11101 gaaatcattc gagaagaatt ggttgaggaa gtcttggcag acttgtctga ggtgccaaaa
    11161 ccaattgaac tcctccatat cttgaaccac tatgtaattg gtcaagatcg tgccaagcgt
    11221 gccttggcag tggcggttta taaccactac aaacgcatca atttccacga tacacgcgaa
    11281 gagtcagaag atgtggattt gcagaagtca aacattttga tgattggccc aactggttca
    11341 gggaaaactt tccttgccca gaccttggct aagagcttga atgtaccttt tgctattgcg
    11401 gatgcgacag ctctgacgga ggctggttat gtgggtgagg atgtggaaaa tatactcctc
    11461 aaactcttgc aggttgctga ctttaacatc gaacgtgcag agcgtggcat tatctatgtg
    11521 gatgaaattg acaagattgc caagaagagt gagaatgtgt ctatcacacg tgatgtttct
    11581 ggtgaagggg tgcaacaagc ccttctcaag attattgagg gaactgttgc tagcgtaccg
    11641 cctcaaggtg gacgcaaaca tccacaacaa gagatgattc aagtggatac aaaaaatatc
    11701 ctcttcatcg tgggtggtgc ttttgatggt attgaagaaa ttgtcaaaca acgtctgggt
    11761 gaaaaagtca tcggatttgg tcaaaacaat aaggcgattg acgaaaacag ctcatacatg
    11821 caagaaatca tcgctgaaga cattcaaaaa tttggtatta tccctgagtt gattggacgc
    11881 ttgcctgttt ttgcggctct tgagcaattg accgttgatg acttggttcg catcttgaaa
    11941 gagccaagaa atgccttggt gaaacaatac caaaccttgc tttcttatga tgatgttgag
    12001 ttggaatttg acgacgaagc ccttcaagag attgctaata aagcaatcga acggaagaca
    12061 ggggcgcgtg gacttcgctc catcatcgaa gaaaccatgc tagatgttat gtttgaggtg
    12121 ccgagtcagg aaaatgtgaa attggttcgt atcactaaag aaactgtcga tggaacggat
    12181 aaaccgatcc tagaaacagc ctagaggtga ctatggaact taatacacac aatgctgaaa
    12241 tcttgctcag tgcagctaat aagtcccact atccgcagga tgaactgcca gagattgccc
    12301 tagcagggcg ttcaaatgtt ggtaaatcca gctttatcaa cactatgttg aaccgtaaga
    12361 atctcgcccg tacatcagga aaacctggta aaacccagct cctgaacttt tttaacattg
    12421 atgacaagat gcgctttgtg gatgtgcctg gttatggcta tgctcgtgtt tctaaaaagg
    12481 aacgtgaaaa gtgggggtgc atgattgagg agtacttaac gactcgggaa aatctccgtg
    12541 cggttgtcag tctagttgac cttcgtcatg acccgtcagc agatgatgtg cagatgtacg
    12601 aatttctcaa gtattatgag attccagtca tcattgtggc gaccaaggcg gacaagattc
    12661 ctcgtggtaa atggaacaag catgaatcag caatcaaaaa gaaattaaac tttgacccaa
    12721 gtgacgattt catcctcttt tcatctgtca gcaaggcagg gatggatgag gcttgggatg
    12781 caatcttaga aaaattgtga ggaaaagaaa atggcaaaaa caattcatac agataaggcc
    12841 ccaaaggcta tcggacccta tgttcaagga aaaatcgttg gcaacctttt gtttgctagc
    12901 ggtcaagttc ccctatcccc tgaaactggg gaaattgtag gagagaatat ccaagaacag
    12961 acagagcaag tcttgaaaaa catcggtgct attttggcag aagcaggaac agactttgac
    13021 catgttgtca aaacaacttg cttcttgagc gatatgaacg actttgttcc ttttaatgag
    13081 gtttaccaaa cggccttcaa agaggaattc ccagctcgtt cagctgtgga ggtagctcgt
    13141 cttcctcgtg atgtaaaagt cgaaattgaa gtcatcgcag agattggata agctagttga
    13201 agtttggtgt tgccaaactt cttttgatat aaggagaaaa agatgacaaa gaaacaactt
    13261 cacttggtga ttgtgacagg gatgagtggc gcagggaaaa ctgtagccat tcagtccttc
    13321 gaggatctag gttatttcac cattgataat atgccgccag ctctcttgcc taagtttttg
    13381 cagctggttg aaattaagga agataatcct aagttggctt tggtagtgga tatgcgtagc
    13441 cgttctttct tttcagagat tcaagctgtt ttggatgagt tggaaaatca agatggtttg
    13501 gatttcaaaa tcctcttttt ggatgcggct gataaggaat tggtcgctcg ttacaaggaa
    13561 accagacgga gtcacccact agcagcagac ggtcgtattt tagatggaat caagttggaa
    13621 cgtgaactct tggcaccttt gaaaaatatg agccaaaatg tggtggatac gactgaactc
    13681 actccacgtg aactgcgcaa aacccttgca gagcagtttt cagaccaaga acaagcccag
    13741 tctttccgta tcgaagtcat gtctttcgga tttaagtatg gaatcccgat tgatgcggac
    13801 ttggtctttg atgtccgttt cttgccaaat ccctattatc taccagaact gagaaaccaa
    13861 acgggtgtgg atgaacctgt ttatgattat gtcatgaacc atcctgagtc agaagacttt
    13921 tatcaacatt tattggcctt gattgagccg attctgccaa gttaccaaaa ggaaggtaag
    13981 tccgttttga ccattgctat gggatgtacg ggtggacaac accgtagtgt ggcatttgct
    14041 aaacgcttgg cgcaggactt atccaagaat tggtctgtta atgaagggca tcgcgacaaa
    14101 gaccgcagaa aggaaacggt aaaccgttca tgagaaaacc aaagataacg gtgattggtg
    14161 gagggactgg aattcccgtc attctaaaaa gtctgcggga aaaagatgtg gaaatcgcag
    14221 ctatcgtgac ggtggcagat gatggtggtt cttcaggtga actccgaaaa aatatgcaac
    14281 agttgacacc gccaggtgat cttcgtaatg tccttgtggc catgtcggat atgcctaagt
    14341 tttatgagaa ggtctttcag tatcggttct ctgaggatgc cggagccttt gctggccatc
    14401 cattgggaaa tctcatcatt gctggcttgt cagaaatgca gggttcaacc tataatgcca
    14461 tgcagttatt gagcaaattt ttccatacaa cagggaaaat ttatccttcc agtgaccatc
    14521 ctttgaccct tcatgcagtc tttcaggatg ggacagaagt ggctggagag agtcatattg
    14581 tagaccatcg aggcataatt gacaatgtct atgtgaccaa tgccctaaac gatgatacgc
    14641 ctctggccag ccgtcgagta gtgcagacca tccttgaaag tgacatgatt gtcctagggc
    14701 caggttccct ctttacctct attttgccca atatcgtgat taaggaaatt gggcgggctc
    14761 ttttggaaac taaggcagaa attgcctatg tctgcaatat catgacccaa cgtggggaga
    14821 cggaacactt tacagatagc gaccacgtgg aagtcttgca tcgtcacctt ggtcgccctt
    14881 ttatcgacac tgtcttggtg aatattgaaa aagtgcctca ggaatacatg aattccaacc
    14941 gttttgatga atacttggtg caagtggaac acgattttgt aggtctttgt aagcaagttt
    15001 cgcgcgtgat ttcatctaac ttccttcgtc tggaaaatgg cggtgccttc cacgatggag
    15061 atttgattgt ggacgagttg atgcgcatta tacaggtgaa aaaatgagtt tcacagtagc
    15121 agtaaaagaa gaaatcctgg gccaacacca tctgagccgg catgaattat ctgccattat
    15181 caaaatgtct ggtagcatcg gtctctcgac ttcgggcttg actttgtcag ttgtgacaga
    15241 aaatgccaaa ctggcccgtc acctctatga gtcctttctc catttctatg aaatcaaatc
    15301 tgaaattcgt caccaccaac ggagcaatct tcgcaagaat cgcgtctata ccgtttttac
    15361 agatgaaaag gtgcaggatt tgttaagtga tttgcacttg gcagactctt tctttggcct
    15421 ggaaacaggt attgatgagg cgattttatc ggatgaggaa gcaggtcgtg cctatctctg
    15481 tggcgctttc ttggtaaatg ggagcattcg tgaccctgag tcaggcaagt accagttgga
    15541 aatcagttct gtttatctgg accacgcgca aggaattgcc tcccttctcc aacagttttt
    15601 actggatgcc aaggtgcttg agcgcaagaa gggggctgtg acctatctcc agcgagcaga
    15661 agacattatg gacttcttga tagtaatcgg agccatgcag gcacgtgatg attttgagcg
    15721 ggttaagatt ttgcgagaaa cccgtaacga cctcaatcgg gctaataatg ccgagacagc
    15781 taatatcgct cggacagttt ctgccagcat gaagaccatt aacaatatca gtaaaataaa
    15841 agatatcatg ggcttagaaa atttgccagt agatttgcag gaagtggcgc aactgaggat
    15901 tcagcaccca gactactcta tccagcagtt agcagatagt ctcagcaccc ctctgaccaa
    15961 aagtggtgtc aatcacagac tcagaaaaat caataagata gcggatgaat tataaaacca
    16021 cgaatcctat gtgactcgtg gttctttttt ataaactggt agagtgtttt ggttgtactt
    16081 tttgttcagg gtcaatgtag ttgatagcgt tgttgacagc agttggagct tctccgaggc
    16141 ctgtcgcaat cagatcaatt tttccgtcat agtagcagca gtcaccgata gcatagatac
    16201 ctgcttggct ggattcctgt ttgctgttga cgataatctt gtgacggttg aggtcgagcc
    16261 cccagttttt aaggttaccg acagaagatt tgaaaccata gttgacaaag aggtggtcta
    16321 ggtcaatggt ttcagtttca tcagatttga cttttgtgat ttcaagttta tcaagtgttt
    16381 ttccatttcc aaggagttgg ctaggggcga atggtgtctt gatggttaca gatgattctt
    16441 gcaaggcttg aacactgtgt tccaaggcac ggaaattatc tctgcggtga acaagggtag
    16501 ttggtgcgat tttttcaaaa gccaaagtcc aatccacagc cgagtctccc ccaccaagaa
    16561 tcgtcacttt tttaccagcg tattgctgaa tgttagaaac gtggtagtgg atattttcat
    16621 agccctcaac cccttcaagt tccagcggac gtggtttgaa ggcaccgcca cccatagcga
    16681 tgataactgt tttagtcagg tgacttcctt tagaagttgt gatggcaaat tcttcttctt
    16741 gtttgtcaat ctcaagaacc gtttcattga gatgaatagg ggtatcaaat ccatttagct
    16801 gttcaatcaa gcggttagtc aactcttctc cagtcaggtt tgggaagcct ggtacgtcta
    16861 ggatttcctt ttcagggtag agaatagcag gttgtccacc tagctgggga agagagtcga
    16921 tgatttgaac cttggcttgg cgtaggtggg cataaaaggc tgcaaaaagc ccgacaggac
    16981 caccacccac aatggtaata tcatagagtt gagacatagt ttctcctttg ttttttctag
    17041 tcagtttatt ttatcatatt tttgttcaat gtaaaatgga ctaggatagg gaaaaaaatg
    17101 ccagaaaatg gtataatagg acgaaagtgt tttgataggg aggatatcag ggatgaattt
    17161 tcaacaatta tccaatttgc aatattggac cagtttgttt gcaagtccat ggacgatagc
    17221 tatcaatctg attgatattt tgattgttgc ttatatttta taccatttta caaaagctat
    17281 tgcaggaacc aagattatga ttttggtacg tggagttttg gtatttattt tagctcaaat
    17341 ccttgcaaat atgattggtt tgactacgat ttcttggtta atcaatcaaa ttattactta
    17401 tggggttatt gcggcggttg ttatcttctc tccagagatt cggactggtt tggaacgttt
    17461 gggaagagcg acagatttct tttccaatgc ccctattagt gctgaggaac agatgattcg
    17521 tgcctttgtt aagtctgttg aatacatgag tcctcgtaaa atcggggcct tggttgctat
    17581 tcagcgtgta cgtaccttgc aggagtatat ttcgacagga attcccttgg atgctaagat
    17641 ttctgcagaa cttctcatta acatttttat tcccaacact cccctacatg acggtgcggt
    17701 gattatcaaa gaagaacgta tcgctgtgac gtctgcctat ctgcccttga caaaaaacac
    17761 agggatttcc aaggaatttg ggaccagaca ccgggcggct atcggtttat cagaagtctc
    17821 agatgccttg acttttgtcg tatcagagga aacgggagga atttcgataa cctataatgg
    17881 aaggtttaag cacaacctaa cacttgatga atttgaaaca gaattacgtg aaatcttact
    17941 tccaaaagag gaagtaggtc ttagttttaa agaacgattg ctaggaggat ggaaacatga
    18001 aaaaaaatag tttatatatc atatcctcac tcttttttgc ttgtgtctta tttgtctatg
    18061 ctacggcgac gaattttcaa aacagtacca gtgctaggca ggtaaaaacg gaaacctata
    18121 ctaatacagt aacaaatgtc cctattgaca tacgctataa tagtgataag tattttatta
    18181 gcggttttgc ttcagaagta tcagtggtct tgactggtgc aaatcgccta tcgctagcta
    18241 gtgaaatgca agaaagtaca cgtaaattca aggttactgc tgacctaaca gatgccggtg
    18301 ttggaacaat tgaagttcct ttgagcattg aagatttacc caatgggctg accgctgtgg
    18361 cgactccgca aaaaattaca gtcaagattg gtaagaaggc tcagaaggat aaggtaaaga
    18421 ttgtaccaga gattgaccct agtcaaattg atagtcgggt acaaattgaa aatgtcatgg
    18481 tgtcagataa agaagtgtcg attacgagtg accaagagac attggataga attgataaga
    18541 ttatcgctgt cttgccaact agcgaacgca taacaggtaa ttacagtggt tcagtacctt
    18601 tgcaggcaat cgaccgcaat ggtgttgtct taccggcagt tatcactccg tttgatacaa
    18661 taatgaaggt gactacaaaa ccagtagcac caagttcaag cacatcaaat tcaagtacaa
    18721 gcagttcatc ggagacatct tcgtcaacga aagcaactag ttcaaaaacg aattaaaaat
    18781 agaaaaggat tttataacaa tgggtaaata ttttgggact gatggagtcc gtggagaagc
    18841 taacctagaa ctaacaccag aattagcctt taaactagga cgttttggag gctatgttct
    18901 tagtcaacat gaaacggaag cgccgaaagt ctttgtagga cgtgacacac gtatttcagg
    18961 ggaaatgcta gaatcggcct tggtggcagg tctcctttca gtagggattc acgtatacaa
    19021 acttggtgtc cttgcaacac cagcagtagc ttacttggtt gaaactgaag gagcaagtgc
    19081 tggtgtcatg atttctgcta gccacaatcc agctcttgat aacggaatca agttctttgg
    19141 cggtgatggc ttcaaactag atgatgaaaa agaagcagaa attgaagcct tgctagatgc
    19201 tgaggaagac actcttcctc gtccaagtgc agaaggctta ggaattttgg tagattatcc
    19261 agaaggcttg cgtaagtatg aaggatacct tgtttcaact ggaactcctc ttgatggaat
    19321 gaaggttgcc ttggatacag ctaatggagc agcttctacc agtgcccgtc aaatctttgc
    19381 agaccttggt gcccaattga cggttatcgg ggaaacacca gacggtctta acatcaacct
    19441 taatgttggt tcaacacatc cagaagccct tcaagaagtg gtcaaagaaa gtgggtcagc
    19501 tattggtttg gcctttgatg gagacagtga ccgcttgatt gctgttgatg agaatggtga
    19561 catcgtcgat ggtgacaaga ttatgtacat catcggaaaa tacctttctg aaaaaggaca
    19621 attggctcaa aatacaattg tgacaactgt tatgtctaac cttggtttcc acaaggcctt
    19681 gaatcgcgaa ggtattaaca aggcagttac tgcagttggt gaccgctacg ttgttgaaga
    19741 aatgagaaaa tcaggttaca accttggtgg tgaacagtct ggtcacgtta tcttgatgga
    19801 ttacaatacc acaggtgatg gtcaattatc agcaattcaa ttgactaaaa tcatgaagga
    19861 aactggtaag agcttatcag agttggcggc agaagtaacg atttatccac aaaaattagt
    19921 taatatccga gtggaaaacg tcatgaagga aaaggccatg gaagtgccag ctatcaaggc
    19981 catcatcgag aagatggaag aagaaatggc ggggaacggc cgtatccttg ttcgtccaag
    20041 tggaacagag cccctcttgc gtgttatggc agaagcgcct acaacagaag aagtggacta
    20101 ctatgttgat actatcacag atgtagttcg tgctgaaatt gggattgact aaatcctaga
    20161 aaactagatg aaaataaaaa attatggtac aatagcttat aatattgtag ccgatggaga
    20221 aagacatgaa tcttaaacgt gaacaagaat ttgttagtca gtatcatttt gatgcacgta
    20281 attttgaatg ggaaaatgaa aatggagctc ctgaaaccaa ggtggatgtg aatttccaat
    20341 tgctccaaca tgaccaagaa aatcaagtga cttccttgat tgtcattttg agctttatga
    20401 ttgtatttga taagtttgtc attagtggaa caatctcaca agtaaaccat atcgatggcc
    20461 gtattgtcaa tgaaccaagt gaattgaacc aagaagaggt ggaaaccttg gctcgtccat
    20521 gtttgaacat gctcaatcgt ttgacttacg aagtgactga aattgcatta gacttaccag
    20581 gaattaattt ggagttctaa tatgaaatta gctgttttca cagattcctc tgcttatctc
    20641 agtgaagaga ccttgcaaag agaagacttg tttgtcttgg atattcctgt caatattgat
    20701 ggtgaggaat atgtcgaagg catcaatctg tctgctgagg aattttacca aaaaatggct
    20761 caggcttctg aattgcctaa gaccagtcaa ccaagtattg ccaagttaga tgagatctta
    20821 acttcgctca aagaacaagg ctatacacat gccttggggc ttttcctatc ttctggaatt
    20881 tcaggttttt accaaaatat ccagtatatg gtcgatgact atgagggctt aaccattgct
    20941 ttcccagaca ctttgattac aagtgctccc ctaggcatca tggttgaaag cgtctttaat
    21001 tggcgtgatc agggcgatga ttttgccagc attcaggata agctagccat tcaaatcagc
    21061 cgtacgtcag cctttatcat ggtagatgac ttggatcatt tggtaaaagg tggacgcctt
    21121 tcaaatgggg ctgccatttt gggcaatttg cttagcatta agccaatcct ttattttaac
    21181 gatcaaggtg tgattgaagt ttacgaaaaa gttcgtactg aaaagaaggc caccaagcgc
    21241 ttaattgaaa ttatcaagga aacaacggct tcaggtcaat accgggtcat tgtcattcat
    21301 gggaatgctc ctgaaaaggc tgaagaattg cgtcagcact tgcttgattt tggcttgggt
    21361 tcggatgttt cacttgctac atttggtagt gtcattggaa cgcacctagg agcaggaagt
    21421 attgctctgg gttatattcc agtgatttag ttggcgcttc taggctagtt aagatgcctt
    21481 gtatcttaga aattgaacac ggactacctg cctcttgaaa aaagatgcct gtcttgcctt
    21541 tcgtggaaag tcagtgccat tccctatttt tcagaggcag ctaaggtcct ttgtatcttg
    21601 ataattgaac acgcctggaa ccctgtgtga aaaagatagt tcttccaaga agtagacact
    21661 tcttgattgg aattcctatt ttcactttgt gttcttacgg actttgtatc ttagacagga
    21721 gtagagatga gtattcgagt aattattgcc ggttttaagg gaaagatggg ccaggctgct
    21781 tgtcagatgg tattgactga tccagacttg gacttggtgg cagttttgga tccttttgag
    21841 tctgagtcag aatggcaggg tattcctgtt ttcaaggata aggctgattt agctggtttt
    21901 gaagcggatg tctgggtaga ttttactact ccagctgttg cctacgaaaa tacacgtttt
    21961 gctcttgaaa atggctttgc tccagtagtt ggaacgactg gtttcacgag tgaagaaatt
    22021 gcagagctaa aagaattttc tcgtgcccaa gacttgggtg gcctgattgc ccctaacttt
    22081 gccttgggtg ctgtcttact catgcaattt gcgacgcagg ctgccaaata tttcccaaat
    22141 gtggagatta ttgagctcca tcatgacaag aaaaaggatg ctccgagtgg aacagccatt
    22201 aaaacagctg agttgatggc agaggttcga gagtccattc agcaaggcgc agcagatgag
    22261 gaagagctga ttgctggtgc tcgtggtgct gactttgatg atatgcgcat ccactcagtt
    22321 cgtttgccag gcttggtagc tcatcaggaa gtcatctttg gcaatcaggg agaagggttg
    22381 accctccgtc atgactccta tgatcgcatc tccttcatga caggagtcaa tttgggaatt
    22441 aaagaagttg tcaagcgtca tgagcttgtc tatggattag aacacttatt atgagattaa
    22501 cgcaaatgcc ttctgaattt cagaaggctt taccagtatt agaaaaaatt aaagaagcag
    22561 gctttgaggc ttattttgtt gggggctctg ttcgagatgc ccttctccat agccctatcc
    22621 acgatgtgga tattgcgacg tcttcttatc cagaagagac caagcagatt tttccgcgaa
    22681 cagccgatat cggaatcgag catggaaccg tcttggtctt agatggggat gaggagtatg
    22741 aggtaacaac ctttcggaca gaggatgtct atgtggacta tcgcagaccc agtgcggttt
    22801 cctttgtacg atcgctagaa gaagacctca aacgccgtga tttcacagtc aacgcctttg
    22861 ccttggatga gacaggagaa atcgttgact tgttccatgg tttagaagat ttggaaaagc
    22921 aagtcttgcg agcagttgga gtggctagtg agcgtttcaa cgaagatgct ttacggatta
    22981 tgcgtggttt ccgttttcag gctagtcttg gttttgcact tgagccagaa acatttaaag
    23041 ctatgaagac cttgacgccg cttttggaga aaatttctgt agagcgtacc ttcgtcgagt
    23101 ttgataaact cttgctggct ccattttgga gaaggggctt ggcttccatg attgagagtc
    23161 aagcttatga ctatctccct gatatggcat ctagccagga caagctcaac agactgtttg
    23221 atttggagac tgattttact tttgaatcct ctgaacaagc ctgggcggct ttactatggg
    23281 ctttggagat tgaaaatgcg cagtcatttt tgaaatcttg gaagacctca cgccagtttg
    23341 ccaagcaagt tcaggatttg ctgattattt tggctctgcg tgaaaatgga gaattgagta
    23401 agcgagattg ttatcgcttt gacatagatt tgcttttaca ggctgaaaat cttcgtcaag
    23461 ctcaaggaaa agaagtcaac ccacaagcca tcacagaaaa ataccaaagc ttgactatcc
    23521 atgacaagaa agagattcag attaatggcg atattttgat caaggaatat ggctatcagc
    23581 caggcccaga cttgggagag attttaacag agattgagtt tgccattgtc gatggagaat
    23641 tggagaataa tcgtgaagcc atccatgctt acctgaggga gaaaaaatga gtgattttat
    23701 cgttgaaaaa ctaagtaaat ccgttggtga caagaccgtt tttagggata tttcctttat
    23761 tatccatgac ttagacagaa ttggtttaat cggtgtcaat gggactggca agaccaccct
    23821 tttggacgtc ctttctggtg tttctggatt tgatggggat gtcagtcctt tttcagctaa
    23881 aaatgattac cagattggtt acttgactca ggatcctgat tttgatgata gaaagacagt
    23941 tttggatacg gttctatcta gtgaactcaa ggaaatccag ctcattcgtg agtatgaatt
    24001 gattatgctc gactatagtg aggacaagca ggcgcgtttg gaacgtgtca tggcagagat
    24061 ggactctctc caagcttggg aaatcgaaag tcaggtcaag accgttctta gcaaattggg
    24121 cattcaagac ttatctactc ctgttgggga attgtcaggt ggtctgagaa gacgggtaca
    24181 gttggcacaa gtcttacttg gcaaccacga cctcttgctt ttggatgagc cgaccaacca
    24241 tctggatatt gcgattattg agtggctgac cctctttttg aaaaattcta agaagaccgt
    24301 cctttttatc actcacgatc gttatttctt agacgctttg tcaacacgga ttttcgagtt
    24361 ggatcgtgca ggcttgaccg agtaccaggg caattaccag gactatgttc gcctaaaggc
    24421 ggaacaggat gagcgcgacg cggctcttct tcacaaaaaa gaacaactct acaaacaaga
    24481 actggcctgg atgcgcagac aaccgcaggc gcgtgcgacc aagcagcagg cccgtatcaa
    24541 tcgattccat gatctgaaaa aggaagtttc aggcagtagt gctgagacag acttgaccat
    24601 gaactttgaa accagtcgga ttgggaagaa agtcatcgag tttcaggctg tttcctttgc
    24661 ctatgaaaac aagcctattt tgcaagattt taatctcttg gtgcaggcca aagaccgtat
    24721 cggaatcgtt ggggacaatg gtgttggaaa atcaaccctg ctcaacttga ttgcaggaag
    24781 tcttgagcca actaaaggac aagttgtgat tggggaaact gttcgcatcg cctatttctc
    24841 tcagcaaatt gagggtttgg atgaaagcaa gagagttatc aattacctgc aggaagtggc
    24901 agaagaggtc aagaccagtg gcggttctac gacttcgatt gcagagttgc tggagcagtt
    24961 ccttttccca cgttcgacgc atggaacctt gattgagaaa ttgtcagggg gtgagaaaaa
    25021 acgtctttat ctcctcaaac tgcttttgga aaaaccaaat gttcttcttt tagacgagcc
    25081 aaccaatgac ctagatattg caactttgac agtcttagag aatttcttgc aaggttttgc
    25141 aggtcccgtt ttaacagtca gtcacgaccg ctatttcttg gataaggtag cgaccaagat
    25201 tctcgctttt gaggatagca agattcgtcc tttctttggt cattacaccg actatcttga
    25261 tgaaaaagct tttgaaacag atatggccaa tcaagtgcaa aaggtcgaaa aggaaaaagt
    25321 ggtcaaggtt cgagaagaca agaaacgtat gacctaccaa gaaaagcagg agtgggcaag
    25381 tattgaaggt gatattgaaa ccttggaaaa acgtatcgct gctattgaag aggaaatgca
    25441 ggctaacggc tctgactttg gtaagctggc tactctccaa aaagaattgg atgagaaaaa
    25501 tgaagcactc cttgaaaaat acgaacgcta tgagtatctc agtgaatttg atagttaaga
    25561 ctattcgaaa atcaaagtgc aaactatgtc ggcttcacat tgccgactca agtacagcct
    25621 gtgaccggct tcctaatttg cactttgatt tttattgagt ataaaagaat agaaaaatcc
    25681 cgtctcatga aaggatttct ctattctttt ttggtttctt gatgaaagat attttgccag
    25741 gtttcgtggc gacgccagat actggtatgg atgataccat ctaactcata gcagatgagt
    25801 ttggtttttt gactgatgga agtaatttga atgtccttga tagcagaatt taactctttt
    25861 ttggtcttat aagcctcttt atccatctgc tctccatctt ggcgaatata gacaaaatca
    25921 tcagtcaaga gttcttctag ttggtttcct tggtcaatca attgttcacg cataagcaat
    25981 tttttataga cattgtctaa aatttcatcc tcagagatag gtgctggttc gatatggaca
    26041 tcggtatcaa agacgccaaa acgctcctcc agcatagact cgacctgatc cgcgatttca
    26101 tggctttcaa aaacagacaa gtcaggattc atctctagtg taatatccag gtagatgttg
    26161 ctaccgtagg tgcgacctct ttgcgatttg accttgctga ttttgggaat ttccatgata
    26221 gccttttggt agtcctcgag caggcggtcg tcaaagccat ctgaaagact aaaggaagac
    26281 tcgatgaaga tatcataggc agtcttcaag ataaagaaag tgatgatgat agcaaccagt
    26341 ttatccacaa tcggataatt gaaactacta gctaggatgg caatggcggt tccaagtgag
    26401 gtaacagcgt cagaaagatt gtccttagca gctgccttca gcgccttgga gttggatttc
    26461 ttactgaggc gagtattgta gagatagacc acaaacataa tcgctgcaga aatgattcct
    26521 agagttgcac caagaggatc aatgaccgtt tcttcccgac tgagaatctt ttgaatggta
    26581 tctcttagaa catcgaaacc gacatagaac atgatgatag aagtgatcaa gcttgccaaa
    26641 tcttcaatct tccaatgacc aaaacggtgg tcacggtctg caggctggcg cgccatccga
    26701 atcccgatta agagggccac atttccaatg atgtccgata cgttattaaa accatcggcc
    26761 accaaactgg atgaatgaag gagatgacca gctgctaatt tggctgcaga caagatcaaa
    26821 taggtcgaaa tactgataat ggctccacgc tcagctaact tgagatttga gatagattgc
    26881 ttcattcaac ttcctttcta gtcacatagc attctaccat tatactggtt ttcaaggaaa
    26941 aattcaaata aggcagtttt tactctttga aaactcccca aaatttggta taatggtact
    27001 actcaaggga gtagctggca gaaacctgtg atagtgtcgt cattccgaat tttatgctga
    27061 aaagtatgct ttccggccct atcttaaaca gcgagacttg ttatgattaa caggtctctt
    27121 tttgtttgtc gtgaaaagat atgacagaaa gagagtctgt tttgcacaca atgtcaagga
    27181 ggagacacat gtcaaaagaa caaaaacgcc aagcgtttta tactcagagc cctgaagagg
    27241 tcttgcaggc tgtggatgcg accgagcaag gtttgtcatc aagtgaggcg gaaaagcgcc
    27301 ttgctgaatt tgggcacaat gaactcgaag aaggcgagaa acgatcaatc ttggtcaaat
    27361 tcatcgagca atttaaggat ttgatgatta tcatcctagt tgcggcagca atcttgtcag
    27421 tcgtgacttc tggtggggaa gatatcgcag atgccattat catcctagct gtggttatca
    27481 tcaacgctgc ctttggtgtt taccaagaag gaaaagctga agaagctatt gaagccctca
    27541 aatccatgtc tagtccagtt gcccgcgttc ttcgtgatgg acacatggca gagattgact
    27601 ctaaagaatt ggtaccaggc gatatcgttg cccttgaagc aggtgacgtg gtaccagcgg
    27661 acctacgttt gatagaagcc aactctctta aaattgaaga agcagccttg acaggtgaat
    27721 ctgtaccagt cgaaaaagac ttgtcagtcg agcttgcgac agatgctggt attggtgacc
    27781 gtgtcaacat ggccttccaa aactcaaacg taacctatgg tcgtgggatg ggtgttgttg
    27841 tcaatacagg tatgtacact gaagttggtc atattgctgg tatgcttcaa gatgcggatg
    27901 agactgatac accactcaaa caaaatttga acaacctttc taaggtcttg acctatgcta
    27961 tcttggtcat tgcccttgtt acttttgtag tgggtgtctt cattcaaggg aaaaatccac
    28021 ttggtgagtt gttgacttct gttgcccttg ccgttgcagc cattccagaa ggacttcctg
    28081 ctatcgttac catcgttctt tctcttggta ctcaagtttt ggccaaacga cattccatcg
    28141 ttcgtaagtt gccagcagtt gaaacacttg gttcaactga aatcatcgct tctgataaga
    28201 ctggtacgct gactatgaac aagatgacag tcgaaaaagt cttctacgat gcggttctac
    28261 atgactcagc tgatgatatt gaactaggtc ttgaaatgcc actacttcgt tcagttgtct
    28321 tggccaatga tacgaaaatc gatgtggaag gtaacttgat tggtgaccca accgaaacag
    28381 cctttatcca atatgccttg gacaagggct atgatgtcaa aggtttctta gagaaatatc
    28441 ctcgtgtagc tgaattgcca tttgactctg accgtaagct catgtcaaca gttcacccat
    28501 tgccagatgg tcgtttcctt gtagcagtca agggtgcgcc agaccaactc ttaaaacgtt
    28561 gtcttcttcg tgataaggct ggggatattg ctccgattga tgagaaggtt acaaatctca
    28621 ttcatacaaa caattctgaa atggctcatc aagccttgcg tgtccttgca ggtgcttata
    28681 agattatcga tagtattcca gaaaatctca cttctgaaga gcttgaaaat gatttaattt
    28741 ttactggttt gattgggatg attgaccctg aacgtcctga agccgctgag gctgttcgtg
    28801 tggctaagga agcgggaatc cgtccaatta tgattacagg tgaccaccaa gacacagcgg
    28861 aagccattgc caaacgtttg ggaatcattg acgcaaacga tacagaaggt cacgttttaa
    28921 ctggtgctga actcaatgaa ctgtcagatg aagaatttga aaaagtcgtt ggtcaatact
    28981 ctgtttatgc ccgtgtgtct ccagaacaca aggttcgtat cgtcaaggct tggcaaaaac
    29041 aaggtaaagt cgttgccatg acaggtgacg gtgtcaatga cgcgccagct ctgaaaacag
    29101 ccgatatcgg tatcggtatg ggaatcactg gtacagaggt ttctaagggg gcttctgata
    29161 tgattcttgc agatgataac tttgcgacta ttatcgtcgc agtggaagaa ggacgtaagg
    29221 tcttctcaaa cattcaaaag actattcagt acctactttc tgctaatact gctgaagtat
    29281 taaccatctt cctatcaacc ttgtttggtt gggatgtctt acagccggtt catcttttgt
    29341 ggattaactt ggtaacggat accttcccag ctatcgctct tggtgttgaa cctgcggaac
    29401 ctggtgtcat gaatcataaa ccacgtggac gcaaggcaag cttcttctca ggtggtgttt
    29461 tgagttctat catttatcaa ggtgtactcc aagcagctct tgttatgagt gtttatggcc
    29521 ttgcgattgc ttacccagtt catgtgggtg acaatcatgc tattcatgca gatgccctaa
    29581 cgatggcctt tgcaaccctt ggtttgattc agctcttcca tgcctacaat gtcaagtctg
    29641 tctaccaatc catcttgaca gttggcccat tcaagtctaa gacctttaac tggtccatct
    29701 tggtatcctt tatccttctc atggcaacaa tcgttgtaga accgcttgaa ggaatcttcc
    29761 acgtaaccaa actagacttg tcacaatggg gaattgttat ggctggaagc ttctcaatga
    29821 ttatcatcgt cgaaatcgtt aagtttattc aacgcaaact cggttttgac aagaatgcga
    29881 tttaagggag gtttcggatg tcagcatatc aattaccgac cgtatggcag gatgaagcta
    29941 gtaatcaagg agcttttacg gggctaaaca gaccaacagc aggtgcccgt ttcgaacaaa
    30001 acttgccaaa aggagaacaa gcttttcagc tttattcact gggaacacca aatggtgtga
    30061 aggttactat cttattggaa gaattactag aagctggttt taaggaagcg gcttacgact
    30121 tgtataagat tgctatcatg gatggggatc aattcggctc agactttgtg aagctcaatc
    30181 caaattccaa gattccagcc ttattggacc agtcaggtac tgaaaacgta agagtctttg
    30241 agtctgctca tattcttctt taccttgctg agaaatttgg agccttttta ccaagtaatc
    30301 ctgtggaaaa ggtagaagtt ttgaattggc tattctggca agcaggtgca gcaccttttc
    30361 taggtggggg atttggacat ttcttcaatt atgctcctga aaaattggaa tatcctatta
    30421 accgttttac gatggaagtg aaacgccagt tggatttatt ggataaggaa ttggctcaga
    30481 aaccttatat tgcaggcaat gactatacga ttgcagatat tgctatctgg tcttggtatg
    30541 gacagttagt tcaaggaaat ctttaccaag gttctgcaaa attcttggat gcctcaagtt
    30601 atcaaaatct agtaaaatgg gcagaaaaaa ttgccaatcg tccagctgtt aagcgtggct
    30661 tggaagtaac ttatacagaa attaaatagc aaaaaagtca tcttcggatg gctttttgct
    30721 acagttgagg gaaagggttt gcagttatcg gcttttgtgc tataattgct ataatatagt
    30781 aaaaagcaag aggagtgtga ggaagtggaa aagaaaattg tgaaggatat cttattttta
    30841 tctcaagtgt ctcatccggc aagtcaggag gacctttatc ttgccagaga tttgcaggat
    30901 acactcttag caaatcgtga tacctgtgtt ggtctagctg ccaatatgat tgggatgcag
    30961 aagcgcgtga ttatctttaa tcttggcttg gttcccgtgg tcatgtttaa cccagtgctt
    31021 ctgtcctttg aaggatccta tgaggcagaa gaaggctgtt tgtccttggt aggtgtgaga
    31081 tcaactaagc gttatgaaac cataaggctt gcctatcgtg acagcaagtg gcaggaacag
    31141 accattacct tgacaggctt cccagctcag atttgccagc atgagctgga tcacttggaa
    31201 ggacgaatca tttaggagga aagcaaatga aacgaatagt ctttgaactt atttttatcg
    31261 caacgacctg gtatatcttt ttaccgcccc ttaacctgac cagctgggaa tttctcttct
    31321 tcctctgtgg gcatttgtta gttgtggcaa tcttatttgg ctttggcaag gggataaacc
    31381 ttgtcaaaac ggttcatgtg cgccacggta aggcggaagc tgccttaaat cttgagggtt
    31441 tcaaaatcaa tcggttaggg aaaattctgt tagcttcgat tggaggaatt cttctcttgg
    31501 cagctttggt ttccttggta acttctagca tgtttcaggc taaaaattat gccaatgtag
    31561 tcacggttac ggaaaaagac tttactgaat ttcctaagag tgacaccagt aaggttccta
    31621 tcctagatag aagtactgct gaaaaaattg gagaccgcta cttgggttcc ctaaccgata
    31681 aggtgtcgca atacgtagcg gcagatacct atacccaatt gacaattgat gggaaacctt
    31741 atcgggtcac accactagaa tatgcagacc ctatcaaatg gtttaacaat caagccaagg
    31801 gaatcggtga gtatatcaag gtggacatgg taactggaaa tgcggatttg gtggacttga
    31861 agacaccaat caagtattca gactcggagt attttaaccg tgatgtcaaa cgtcacctgc
    31921 gcttgaagta cccgaccaaa atctttaaaa ctccatcttt tgaggtggac gatgagggca
    31981 atcctttcta tgtagcaacg gtttaccaaa agcaatttgg acttgctgtt cctcgtcctg
    32041 cttcagtcat tatcttggat gctacaaatg gagaaaccaa ggaatacagc ttatcagatg
    32101 ttccagaatg ggtggacagg atctatccag cagaggaaac cattgagcaa atcaactaca
    32161 acggcaagta caaggacggt ttcttgaatg ccatgatttc caagaaaaac gtgacccaga
    32221 cgaccaatgg ctataattac ttgtctatcg gtaatgacat ctatctctac acaggtgtga
    32281 cgtcggctaa tgcggatgag agtaatcttg gtttcatcct tgaaaatatg cgaacaggag
    32341 aaattactaa gtatagcttg gcttctgcga cagaagaatc agcccgtgaa tcagcagaag
    32401 gtgctgttca ggagaaatcc tacaaagcaa ccttcccaat cctcatcaac ctcaatgaca
    32461 agcctctcta catcatgggc ttaaaggaca atgctggctt ggtcaaagag tacgccctgg
    32521 tagacgcagt cgagtaccaa aatgttatcg ttgctactac agtggaagag atgctcagca
    32581 agtatgccaa taaaaacgac cttgaaattg acaatgcaac gacagaaagc atcaagggag
    32641 tagtagcaga cctcaaatca gctgttatca agggagacac tgtctacttc tttaaagttg
    32701 atggcaagat atacaaggta aaggcttcag tatccgatga ccttccttac cttgaaaatg
    32761 gtaaaacctt cgaaggtcaa gtaggaaaag acaattatct caagaccttt aaagtacaat
    32821 aatactcttc gaaaatctct agctctatct gcaacctcaa aacagtgttt tgagcagcct
    32881 gcggctagtt tcctagtttg ctctttgatt ttcattgagt ataaaaaagg tttatttaat
    32941 aaatatatgt tataataagg taaattaagc ctaatggagg acaaagaaat gggtttttat
    33001 ttgatggttg cttcaatgct actcggactg ctcgctttga agataggttt ttctcagttc
    33061 aaggagaaaa aagataaatt cttatctatc ttaacaagtt tagctggcac agcccttgtt
    33121 ctcgtggctg tctggttagg atggcccaaa taaatagaaa aacctcggtc aaaccgaggt
    33181 ttttcaaatg aatttcttgg ttgtggctaa aaaatatgct acactatcaa tatgaaaatt
    33241 ttaatcccaa cagcaaaaga aatgaacaca gacttgccaa gtatcgaggc aattccttta
    33301 aaaccagaaa gtcagaccgt gcttgatgcc ttggctctct attctgccag tcaattggag
    33361 agtttctaca aggtatcagc tgagaaagcg gcggaagaat ttcaaaatat ccaagctttg
    33421 aaaaggcaaa ctgctcaaca ctatccagcc ttgaaacttt ttgatgggct tatgtaccgc
    33481 aacattaaga gagataagct gaccgaggcg gaacaagatt atcttgaaaa tcatgtcttc
    33541 attacctcgg ctttgtacgg tgttgttcca gccttgtcac ccatggctcc tcaccgtttg
    33601 gattttttga tgaaattaaa agtcgctggt aagactttga agagccattg gaaggcagtc
    33661 tatgatgaag ctctgaagaa ggaagaagtg attttctctc tcttgtcatc agagtttgag
    33721 actgtatttt ctaaggaaat cagagcaaag atggtgacct tcaaattcat ggaggataga
    33781 ggcggtcagc tgaagattca ctcaactatc tccaagaaag cgcgcggggc ctttctaaca
    33841 gctttaatag aaaatcaagt acaaactgtg ggggaagcac gtcgcttgaa ctttgctgga
    33901 tttgtttacc gagaagattt gtcacaacca cagggattgg tttttgtaaa ggaagtatag
    33961 aaatcagata agagaaaagt cagcacgatt atgctgactt ttttgataac ttataaagta
    34021 ttggacaaat gaatctcatt tgataaggtg ttaagatgat taaccaaatt catgattgac
    34081 agatgatttc ggcaaataaa cttcttggta atccctgaaa tatagaaatt agacacgatg
    34141 atatcgtaat ctgtctgatt taaaatctca ggacttgttt ttaattcatc ccaaatatcg
    34201 aaggtaaagc ggttattaca gtaataggaa agcatatcaa caaaggtaag ggatatagca
    34261 tggtcaaagt tactgataat caaaaccttg ataggtggtc gattttctaa caactgagta
    34321 gagaggtttt cagcatgggt taagatggtg tacatcaagt gttccaactg ttcaggatgg
    34381 tcatgctgtc caattgcctg acggtattga gccagttctt gacgcgcact tcccataaag
    34441 tctgggaagt aaccttcaaa ttttttaatc gtcaatgctt tttgttcaaa taagattggg
    34501 gtagaaaaga tttcctgtct ttcaaagaaa gcagtgttgt gtaaatgcca aatcagctca
    34561 tcgtggttag taaaagtaat cttatattgt tttgataggc gttctaatat ttgactaagt
    34621 aattggtaag agtatcttgc ttgactgtta tcttctaaag agttgaagaa ttcttgagga
    34681 tctaggaaaa tatcattctg aagaaaagaa ataaaaattt gagcgattgt atctggagtc
    34741 atttcaagcc caaaatgttt agagaaataa gcaagtgtct cctggaaatt tggaatgctc
    34801 tttaaaagag gataatattc tttgtaaaag tggttgggga ggtcaatgaa gtgaccattt
    34861 ttaaccctgt ggatactgat agctatcatc agtttgtaca ttctataaat tgaaaatcgc
    34921 attggataat tcgtgatttt atagaagaag tcagcaaact ctgttaaatc ttcctcagga
    34981 aggtcaggaa aaggccaatc taggaaataa tagcgctcag aaaagtattg ggcaaaaaag
    35041 taacgaatat cgatctcatt tccacgtatc tcggatggag taaaagataa ttcaatttga
    35101 aactgagatg aaagaacctt tgtaatattt ctgcccagtc gatagaggtt ggcactacta
    35161 aagtaaagat tttctattgt tcgataaata ggtagcccct cattgaagaa catatactct
    35221 agtaattgaa aagattgaga attagcaaga aaatattgat aaatatcttc tacactagtg
    35281 ttaacttcta aatctatcat gattccgtta acagaagatt ggatgttaat agatggaaag
    35341 gcaatacgta attcatttaa atcacttttt aagattcgtt ctgtacatcc taatttttcg
    35401 gctagttcat gtaatttcat ccaattacga ttctgaatta gggtttccat taagcgtaat
    35461 tgtctttgaa cttttgtgga taaaaggttt ctcatacggg tatttcctcc ataattcatt
    35521 atatcttttt ttgtctaagt agtataaaaa aattagagca agaaaattgt cgttagtaat
    35581 cggaaaaatt agaataatat aagtggcttt taagtgcaaa aacagaatat attaattgtt
    35641 cagaaaatat tgattaatgc ctcaaatagt tgtacattgt aaactataaa atactatcta
    35701 ggagtttaaa atgaaacatt cacataaaaa atcatttgac tggtatagca tgcaacaacg
    35761 ttattctatt cgtaagtatt actttggtgc agttagtgtc ttgctcggta ccgctttggt
    35821 attaggtgca gcagctagtg tccaaacagt acaagcggaa gaaaacaaac aagaaactac
    35881 caatagtatt tctgttggta ggggagaagc agctactaaa ccagcagagg tttctgcgtc
    35941 taataaagag aaaacctatg cagctccaac tgtagctaat ccagtagaaa cgactccagt
    36001 taaaactgga gaagttacta aaccagcaga aaaagttgaa gaagcaaaag acaaaaaaga
    36061 ggaagtaacg catcaagatg ctattgacaa gtcaaaattg ttaacggctc tttcgcgtgc
    36121 taaaaagtta gaaagcaagt tatatacaga agcaagtgct gctaacttgc aaacaagtat
    36181 ccaagctggt caaagcttgc ttgggaaagc agatgcatct gaagctgaat tatcagcagc
    36241 agagtcatct attcaatcat ctattattgg tctagaactt cgttctaact ctaacaaagg
    36301 aactgtatca gaaactcctg tagcgaagaa agctaatata gttgaagcga aggaagagac
    36361 taatccagct gcaacaactg atcgttcagc tgttgatagt gctgttttgc caactagcac
    36421 agctgccaaa gtagaaacaa cttcagctcc agcatctatt aatgaaatct tgaaaccagg
    36481 tttgagcctt tctgatgctc gccaaaatcc agctatccgt aaggaagatg ttgatagagg
    36541 gtatagtggt tttagagcgg cgcctgctcc aacgaaccaa ccagtaacta atctaggaaa
    36601 taatactgtt ttcactgata ttagcagagg ttctcatact ttccgtggta atggaaattc
    36661 acgtcgtgga aacccgattc attttgatgt aacaacaact agagttagaa atagagtaga
    36721 tttctcaatc agatattcag gaccaggtga gtttgttaat aacaacttta tcttagacaa
    36781 aggaaatgga ttcggagaac cttctcgtgc aactgtttca acaccaaaat taagagacca
    36841 agttaaaaac attagtaagg gtggaaactt tgtttctcat tcaggctaca gtttagaagc
    36901 tgcagtagaa acaagcacca atcaaacaat taagtttagt ttacctatag ccaaccctaa
    36961 tggtgatctg tctgttcgat taagacctgt tacttttaat gtaggtcaag gggaatcagg
    37021 atctgcaact agtaatgatc catatagtaa ctctaactat tacttcagag aaaaaccact
    37081 cctcttggat gcaaatccaa atggtggtac taataataag actgtttcag aagacattga
    37141 cttccaaact gtctatcttc caactagtaa gttaccagaa ggtcaaacta gattagttcg
    37201 agaaggtgaa aaaggacaac gtcaaatcat ctataaagtt catcaattgg gtaacgaaac
    37261 aatcctagga ttgccaatta gtaattcagt tattaaagaa gttaagccac gtattatgca
    37321 aattggtgtg gctaaagatc taatcgatac agtaaaacca cgtgttgatc aaaataaagt
    37381 cggtgataca aataacctca ctttctatct tgataacgat ggaaacggtg tttatactga
    37441 gggcgtagac gaacttgttc aaaaaattgc tattaaagat ggtgctaaag gtgaaaaagg
    37501 agaccgaggc gaacgcggtc taactggagc tcaaggagct aaaggtgaaa aaggagaccg
    37561 aggtgaacgc ggtctaactg gagctcaagg agctaaaggt gaaaaaggag accgaggtga
    37621 acgcggtcta accggagctc aaggagctaa aggtgaaaaa ggagaccga
//
LOCUS       DAVBBO010000016        37452 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ST1
            SAMEA2066453-rid20184263.denovo.016, whole genome shotgun sequence.
ACCESSION   DAVBBO010000016 DAVBBO010000000
VERSION     DAVBBO010000016.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2066453
            Sequence Read Archive: ERR351777
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 37452)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 37452)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980402.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980402.1
            Genome Coverage       :: 176x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:17:33
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,141
            CDSs (total)                      :: 2,104
            Genes (coding)                    :: 1,953
            CDSs (with protein)               :: 1,953
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 16S)
            partial rRNAs                     :: 1 (23S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 151
            CDSs (without protein)            :: 151
            Pseudo Genes (ambiguous residues) :: 0 of 151
            Pseudo Genes (frameshifted)       :: 73 of 151
            Pseudo Genes (incomplete)         :: 76 of 151
            Pseudo Genes (internal stop)      :: 40 of 151
            Pseudo Genes (multiple problems)  :: 32 of 151
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..37452
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2066453-rid20184263.denovo.016"
                     /strain="ST1"
                     /db_xref="taxon:1313"
     gene            complement(<1..777)
                     /locus_tag="VQU30_000790"
     CDS             complement(<1..777)
                     /locus_tag="VQU30_000790"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000032537.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HET2446929.1"
                     /translation="MSKETVVYTKRREKIKDNILGYSFLAPALILLGIFLVIPVGMVI
                     YYAFTDYYLLTPDERKFVGLENFIRLTKDPIFLKSFLNTLKFVVWIIPVQLGAALGMA
                     LIVNKKRKGNMFFKVAFFAPVVMSLVVISILWLYLLNPNSGLLNAILNKVGIASQPFL
                     TSPKQAMYAIVFVSAWQGAGYQMLLFLGGMQNIPQDVYEAAELDGFSKWAQFRYITMP
                     LLKPTALFVLLTTLISAFKLIVQPMVMTQGGPLNSTITMVY"
     gene            complement(873..2183)
                     /locus_tag="VQU30_000791"
     CDS             complement(873..2183)
                     /locus_tag="VQU30_000791"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter substrate-binding protein"
                     /protein_id="HET2446930.1"
                     /translation="MRKGTMLSVVAGLSLAILAGCSGGTNSKQASSSNDIKVWVQFSD
                     ETNEGKAWQKVVDNFNQSGKSKYKVVTEYIPRSGSGGGYEDKVNAAITTNSLPDVITL
                     DGPNTAAYAKSKVITPLDDYLKDNNMDDVLDSIKQQGTYNGKFYAFGFSESNVGVYYN
                     KKMFKEAGIAESELPTLEKPWTWDEFNTIAKKLKDHYNKPAIDFRINSNDEMLPYAYM
                     PLIWSNNGSVVNEDGTKAEGYFNSKESVEAVQFIQNLVKEGYTTVSPVEKGFETGEYP
                     MLLSGSWTIADMNTNYKDIDFGILPYPVSSKTKKLVSPSGSWQLAVTTKSDKKEAASE
                     FVKFATNTESSEIISLGNSVLPIRKSTIENIKDKVSEPMRFLMEQNSKTAHARPVVVA
                     YPQVSRAFQQAMQDISYYEENPNVQKVLDTRTKEMQTAIDQSLK"
     gene            complement(2310..3305)
                     /locus_tag="VQU30_000792"
     CDS             complement(2310..3305)
                     /locus_tag="VQU30_000792"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000230211.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HET2446931.1"
                     /translation="MVEQRKSITMKDVALEAGVSVGTVSRVINKEKGIKEVTLRKVQR
                     AIKTLDYIPDNYARGMKKNRTETIALIIPSIWHPFFSEFAYHVEKELLKYNYKLFICN
                     ADSDSQNEIEYIEMLKQNKVDGIIGITYSDIDKYILSDLPFVSIDRHFSENVCYVTSA
                     NYKGGQTAAEELVRRDNKHLAFIGSINMYENETILRSKGFREKAKELGVDVYNFEMKE
                     PLINPEDQIRIFLQSHKEIDGIFTINDMMALRVISVMKELGKIAPDDYQIIGFDGLKT
                     SVDQSYLVSTIVQDIGMMAKESVAMILKMIKREEILEKRIVIPTYFGGDKTTKKI"
     gene            complement(3667..5148)
                     /locus_tag="VQU30_000793"
     CDS             complement(3667..5148)
                     /locus_tag="VQU30_000793"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001205273.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HET2446932.1"
                     /translation="MRDLLSKKSHRQLELLELLFEHKRWFHRSELAELLNCTERAVKD
                     DLSHVKSAFPDLIFHSSTNGIRIINTDDSDIEMVYHHFFKHSTHFSILEFIFFNEGCQ
                     AESICKEFYISSSSLYRIISQINKVIKRQFQFEVSLTPVQIIGNERDIRYFFAQYFSE
                     KYYFLEWPFENFSSEPLSQLLELVYKETSFPMNLSTHRMLKLLLVTNLYRIKFGHFME
                     VDKDSFNDQSLDFLMQAEGIEGVAQSFESEYNISLDEEVVCQLFVSYFQKMFFIDESL
                     FMKCVKKDSYVEKSYHLLSDFIDQISVKYQIEMENKDNLIWHLHNTAHLYRQELFTEF
                     ILFDQKGNTIRNFQNIFPKFVSDIKKELSHYLETLEVCSSSMMVNHLSYTFITHTKHL
                     VINLLQNQPKLKVLVMSNFDQYHAKFVAETLSYYCSNNFELEVWTELELSKESLEDSS
                     YDIIISNFIIPPIENKRLIYSNNINTVSLIYLLNAMMFIRLDE"
     gene            5591..5755
                     /locus_tag="VQU30_000794"
     CDS             5591..5755
                     /locus_tag="VQU30_000794"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397534.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GlsB/YeaQ/YmgE family stress response membrane
                     protein"
                     /protein_id="HET2446933.1"
                     /translation="MGIIANVFAGLVGAYAGQSLLGSWGPSIAGMALLPSIVGAAIVI
                     TVVSFFTGRK"
     gene            5839..6405
                     /gene="amaP"
                     /locus_tag="VQU30_000795"
     CDS             5839..6405
                     /gene="amaP"
                     /locus_tag="VQU30_000795"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000030212.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alkaline shock response membrane anchor protein
                     AmaP"
                     /protein_id="HET2446934.1"
                     /translation="MSKAKKICFIIFCILILTIFLPVLIDYHQVSDLGIHLLSWRQNS
                     VVEFYLARYVFWGTVVLSTLVLLSILVVMFYPKRYLEIQLETKNDTLKLKNSAIEGFV
                     RSLVSDHRLIKNPTVHVNLRKNKCFVHVEGKILPSDNIADRCQIIQNEITNGLKQFFG
                     IERQVKLEVAVKNYQPKPQNKKTVSRVK"
     gene            6417..6587
                     /locus_tag="VQU30_000796"
     CDS             6417..6587
                     /locus_tag="VQU30_000796"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000455065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2273 domain-containing protein"
                     /protein_id="HET2446935.1"
                     /translation="MEWLKQYRYPIIAGLIGVFLACLIVSFGFFKTIFVLILGALGVA
                     AGLYIEKNYIDK"
     gene            6626..7234
                     /locus_tag="VQU30_000797"
     CDS             6626..7234
                     /locus_tag="VQU30_000797"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000064115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HET2446936.1"
                     /translation="MSNEKNTNTNVEKKDATVVAHEIKGELTYEDKVIQKIIGLSLEN
                     VSGLLGIDGGFFSNLKEKIVNSDDVTSGVNVEVGKTQVAVDLNVIVEYQKNVPALYSE
                     IREIVSSEVAKMTDLEIVEINVNVVDIKTKEQHEADSVSLQDRVSDVAESTGEFTSEQ
                     FEKAKSGLGSGFSTVQEKVSEGVEAVKGAANGVVSHENTRVN"
     gene            7265..7468
                     /locus_tag="VQU30_000798"
     CDS             7265..7468
                     /locus_tag="VQU30_000798"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398938.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CsbD family protein"
                     /protein_id="HET2446937.1"
                     /translation="MSVEEKLNQAKGSIKEGVGKAIGDEKMEKEGAAEKVVSKVKEVA
                     EDAKDAVEGAVEGVKNMLSGDDK"
     gene            complement(7578..7856)
                     /locus_tag="VQU30_000799"
                     /pseudo
     CDS             complement(7578..7856)
                     /locus_tag="VQU30_000799"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007895264.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            8054..8341
                     /locus_tag="VQU30_000800"
     CDS             8054..8341
                     /locus_tag="VQU30_000800"
                     /inference="COORDINATES: protein motif:HMM:NF033563.0"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="HET2446938.1"
                     /translation="MIVSLKTKSRKAKDMAESIQGWLAQFLVNLFKSITFDCGKEFSK
                     WKDISNHHDSESFFANLGCSRQRRLNEHSNRLLRCHDLPKQTDFNEVSQEF"
     gene            complement(8619..9389)
                     /locus_tag="VQU30_000801"
     CDS             complement(8619..9389)
                     /locus_tag="VQU30_000801"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000229327.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfite exporter TauE/SafE family protein"
                     /protein_id="HET2446939.1"
                     /translation="MVEIIYFLIIIIASGLGSISGMGGGIIIKPLMDSFGYHSVSDIA
                     FYSSFSVFIMAIISTIKRFSQSKEIKWRLIFTVSFSSVLGGFLGHLIFQVLLSQLSVR
                     LVSIVQMILLFVMLLVSFVLTDFKKTYQFDKIGFYMICGLLLGLISSFLGIGGGPLNV
                     SLLMVFFSISIKEATMYSLAIIFFSQLSHLATIVVVTGLNQYHLAPVPVIFLASICGG
                     VLGTVVSKVLPENWVRYCFKGMLFFVMGMTLYNLFHIL"
     gene            complement(9404..10252)
                     /locus_tag="VQU30_000802"
     CDS             complement(9404..10252)
                     /locus_tag="VQU30_000802"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000782422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formylglycine-generating enzyme family protein"
                     /protein_id="HET2446940.1"
                     /translation="MKMKKIKGGTFMMGTNSEEGFLDDFEGPQVAVSVKDFSIADTPV
                     TNQEFAQFVKETGYKTLAERQEWSFVFILFVPEAEREGYPHPAGAPWWLQVPNACWKH
                     PYGENSNLVGLEDHPVVHVALEDALAFCNWSGMSLPTEAQWEYAARGGRQSEYPWGDT
                     LLEGGYYHANTWQGRFPYENTALDRFIGTAPVYEFLPNDFGLYQMIGNVWEWCRNPRY
                     TLLASFNEDDYELPKYGIQDEEYAIRGGSFLCHCSYCNRYRVAARNGCISTSTSSHLG
                     FRCLKE"
     gene            complement(10249..11724)
                     /locus_tag="VQU30_000803"
     CDS             complement(10249..11724)
                     /locus_tag="VQU30_000803"
                     /EC_number="3.1.6.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398463.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arylsulfatase"
                     /protein_id="HET2446941.1"
                     /translation="MVQTKQPNIILIVVDQMRADALSLNSKDKLVSTPTLDMMASVGY
                     NFENAYSPVPSCVPARAALLTGLDQDKSGRVGYQDEVPWNFTNTLPKVFKDMGYQTEC
                     IGKMHVFPSRQRLGFDHVLLHDGYLHVDRKYDKAYGSQFDYVSDYLAFLKGKVGYDVD
                     LIDDGMDCNSWEARPWDKDEKLHPTNWVVSESISFLQRRDPTVPFFLKMSFEKPHAPL
                     NPPKYYFDMYMERLPQFLDLHIGNWEVLEKQIPSIYALRGKLKEDDQRRMVAAYFGLI
                     THIDHQISRFLTSLKEFRHDKDTIIWFVSDHGDQLGEHYLFRKGYPYQGSIHIPSFIY
                     DPAGLIAGNRGTIKQLVKIQDIFPSLVDLAGGTTTDELDGRSVKNLLFGQYEGWRTEF
                     HGEHALGKDSSQYILTDQWKFIWFPVLNHYQLFDMKKDPHEMNDLYPSEKYQPIVRQM
                     KKKLVDFLRYREEGFVVDEELVPVELSKITPTLTKTGDSQS"
     gene            complement(12047..13402)
                     /locus_tag="VQU30_000804"
     CDS             complement(12047..13402)
                     /locus_tag="VQU30_000804"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001095003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HET2446942.1"
                     /translation="MNTMLDKMQEKLSPIAMKVGNQKFLVALRDSFVGTMPVIMTGSI
                     ALLLNAFLVDLPQQFHLESITKTFQWLVDINNLVFKGSIPIVSLLFIYCLGVNIAKIY
                     KVDTVSAGLVSLASFVISIGSTVTKSFPLANVGDVKLDQILQGIDNLAFDGKNLMVTI
                     GNVIPGNHINARGYFTAMMIGFLASIIFCKVMKKNWVIKLPDSVPPAIAKPFTSIIPG
                     FMAMYIVAILTYVFHLLSNDLLIDWVYKVLQTPLLGLSQSFFAVILMIFLNKLFWFFG
                     LHGGNVLAPIMEGLFGVAMLANLDAFQKGEPIPYIWTSGSFGAFVWFGGLGLVLAILI
                     FSRNSHYRKVAKLGLAPVLFNIGEPVNYGLPVVLNPLLFIPFVLSPVFMATVAYWATS
                     WGLVSPVTQNVTWVMPPILYGFFSTAFDWRAIILSVVCLIISVLTYFPFVKMADKTEL
                     S"
     gene            complement(13412..13729)
                     /locus_tag="VQU30_000805"
     CDS             complement(13412..13729)
                     /locus_tag="VQU30_000805"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000344536.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HET2446943.1"
                     /translation="MDESNLESVMGLIMYGGEAKSNAMEAIQAAKKGDFSKANRRLAD
                     ANAALLQAHKAQTEMLTREAQGEETSISLLMVHAQDHLMTSLTFVDLAKEVVEVYERF
                     EKN"
     gene            complement(13746..14063)
                     /locus_tag="VQU30_000806"
     CDS             complement(13746..14063)
                     /locus_tag="VQU30_000806"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001151647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HET2446944.1"
                     /translation="MAKVTIMLACAAGMSTSLLVTKMQKAAEDKGLDAEIFAVPAPEA
                     EEIVATKEVNVLLLGPQVRYLLGDFQEKLKDRQIPVAVIPMTDYGMMNGSKVLDLAES
                     LLD"
     gene            complement(14076..15761)
                     /locus_tag="VQU30_000807"
     CDS             complement(14076..15761)
                     /locus_tag="VQU30_000807"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000791288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="family 16 glycosylhydrolase"
                     /protein_id="HET2446945.1"
                     /translation="MKNKKLISSLFILFLLIFIHVKVFANENLIKNSNFEQGELFWNS
                     RNRGIINSNESYSNGHYSGMIPSTAINDNRADGYIGQVIDIEPNEDYLVSAFAKVDIS
                     GAEGYFTARWFDNNKQGEIVQNNIGEAVDQTVNTTEWKKYMFSFNSGKHDKVLIQLVK
                     WSEDDTTKKSNIFIDNVEMYQLSKGNSYKKIWRDDFDGEQLNKKYWGYELGSIRGWEQ
                     QHYVRSDENVFLRSGNLVLRATNRSKEDQYFNPRNNHRKVVYNSGSVRTHGKVEFLYG
                     KLEMRAKLPKGQGVFPAFWTLGSDFTLDGKINPVQGRGWPSTGEIDIMELVGERNSNG
                     SGNKTVYQTLHYGQSDNDDGKFAGRGTAFKLSSGNFNDSYHTFSIDWYKDYIVWMVDN
                     HIVRKVYYGSDNIAKKIFNRPQYVQLNLAMGGSWPGVVDNNLSGTEFVVDYVSYSRND
                     LQQHQAEEYYSQSPKINGAKDIVINRGDVPDLLKGITTNSGYELDYSIENEPMFNNFG
                     GNTSVDLLIRNKTEKEKISQMPPGVYNLHYTSRPKHLDYESKVDRKTVTLTIK"
     gene            complement(15766..16662)
                     /locus_tag="VQU30_000808"
     CDS             complement(15766..16662)
                     /locus_tag="VQU30_000808"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="haloacid dehalogenase-like hydrolase"
                     /protein_id="HET2446946.1"
                     /translation="MKRLISANPSEILQMNAEELKQSILASEGRVVLSENVVTRETFV
                     GDITNSEIARAFGADMILLNCVDVFEPKIYALDSSGDDVIHRLHQLVACPIGVNLEPI
                     DPSAKMLEETQEIVAGRVASVETLNRIEELGFDFVCLTGNPGTGVSNREIIKAVQTAK
                     ENFSGLIIAGKMHGAGVNEPVAELSVAEQLLEAGADVILVPAVGTVPAFHDQELREVV
                     DLVHSKGGLVLSAIGTSQETSDTDTIKEIALRNKICGVDIQHIGDAGYGGLATVDNIY
                     ALSKAIRGVRHTVSRLARSVNR"
     gene            complement(16665..17927)
                     /locus_tag="VQU30_000809"
     CDS             complement(16665..17927)
                     /locus_tag="VQU30_000809"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000413340.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HET2446947.1"
                     /translation="MEKLLQEKLLPVAARLGNNKALVSIRDGITLTIPLLLIGSLLMV
                     IASFPIPGWEKYLGDIGVADYLWKGVDSSFGLLGLVASFGIAYFMARQYKVDGIPAGI
                     VSLSSFITVTPFITGEAGAGMPTAFMASKGLFVAMILGLINGYIYQWFINHNIQIKMP
                     DGVPPAVSKSFSAIIPGAVTIVGWLIVYATLDKLSLPNLHEIAQGALGGPLGLLGNNV
                     IGLLILIFLNSSFWFVGLHGGNVVNAVMKPLWLANLDANKVAYQTGETLPNIFTSVFM
                     DNFVFIGGGGATIGLVLALGYLAHKKKASKQLKTLAPITVIPGLFNINEPAMFGVPIV
                     LNILLLVPFILAPMFNLLVAWGAMASGLVPLTYTDPSWTMPPVISGLLATGSISGSLL
                     QIVLIVLDVLLYLPFVIAIEKRFKLLED"
     gene            18207..19385
                     /locus_tag="VQU30_000810"
     CDS             18207..19385
                     /locus_tag="VQU30_000810"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000175872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family transcriptional regulator"
                     /protein_id="HET2446948.1"
                     /translation="MTLSKKQLQLRAKILETVYTLGPISRIEIATKTGITPATTSSIT
                     NDLIKENILLELGEDEHDTSVGRKKILLDIQAKRFYYIGCELSEKHFTFALGDNLGNI
                     LKEEKEIVTKQLIQEKGNQLINQTLKQFLNNCSDYEIEAIGIALPGRYLDDYKITTNN
                     PLWQHIDLEMIQSHFDKPLFFSNNVNCMAIGKRLFSRQQNDPNFAYFHFARGMHCSYI
                     YDGNIYGKGNLMIGEIGHTVVSSEGEECSCGRKGCLQTFAGESWLIKKSKILYHQSPY
                     SLLPSLVKNADDIDIQVILTAYQLGDTGIITLIHQALLYLSQTILNISMMIDSQKIYL
                     HSPLLTNQHIIQKLYSEMNYKPKLLYNRLPEVIIEPYNDFTAAHSAIALCLYHTILHS
                     "
     gene            complement(19613..20059)
                     /locus_tag="VQU30_000811"
     CDS             complement(19613..20059)
                     /locus_tag="VQU30_000811"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000155432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HET2446949.1"
                     /translation="MTIRFEEKVSIENAQFVCQWSNSLGKSFQEQWMGPRIPFLLPLQ
                     ALEGVFSIFDEQEFVGLIQKIRLEDSNLHIGRFFINPQKQEQDLGSQALRKFVSLAFE
                     NEDIDSISLNVFEANQRAQNLYQKEGFEIVQMVEAPVRKYSGLKLE"
     gene            20129..20788
                     /locus_tag="VQU30_000812"
     CDS             20129..20788
                     /locus_tag="VQU30_000812"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000564993.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prepilin peptidase"
                     /protein_id="HET2446950.1"
                     /translation="MIDFYFFLVGSILASFLGLVIDRFPEQSIISSASHCDSCQTPLR
                     PLDLIPILSQVFNRFRCRYCKVRYPVWYALFELGLGLLFLLYSWELLSLGQVVLITAG
                     LTLGIYDFHHQEYPLLVWMTFHLILIASSGWNLVMVSFLILGILAHFIDIRMGAGDFL
                     FLASCALVFSVTELLILIQFASATGILAFLLQKKKERLPFVPFLLLATCVIIFGKLLL
                     V"
     gene            complement(20840..21991)
                     /locus_tag="VQU30_000813"
     CDS             complement(20840..21991)
                     /locus_tag="VQU30_000813"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000481741.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="XRE family transcriptional regulator"
                     /protein_id="HET2446951.1"
                     /translation="MFNGRVLKELRLLNGLSRAELAQRINLTEQAIWQFESNETKPKL
                     STKMHLANQFHVDLTYFEQEEESIRFDSSVIAFRNADLATRKTIDIQTMYLHKVDSLI
                     DYFESFVIIPNITIHDLSNVVSESYHKGESIEELALYAREKLGISKDNHDLLYKLERS
                     GIYIVERLINGQADAYSAWSKLGRPYIVLGTNKSSVRRNFDLAHELGHILLHKYKDMN
                     EDGDRLEQEANYFASCFLLPKEEFLVKFEERVGKRVSNPDSYILLKSDLNVSIQALEY
                     RAFKLGLLTPKQHSYFYRQIAQKGYKMIEPLDDQIFVKKPSKVKSILDVVLSNHLVSL
                     ATIMSKQSIRLQFISEIFSVEMKFFDQYQEDRRTDRFDNIIPLYKRNNL"
     gene            complement(22006..22737)
                     /locus_tag="VQU30_000814"
     CDS             complement(22006..22737)
                     /locus_tag="VQU30_000814"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000934015.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2446952.1"
                     /translation="MLNQDLFDSLEAQKIVDTLMKGQKDYVDERLEKRETMIVSNGYA
                     WTRPNHIDTAFASADLFEYKLQLAGQTWGYLEFETNTEKYGKVLLIIKGKKRLTNQFP
                     LVQKNKSGYLFEYAQMNTLYLNQHSSYKNDEDSHSFPIQMELVSDEMIQEIEQATKNS
                     NIEKFMILTYEADSENNIISVDVVMPDARTGQLHLIQDLSEYIQSSSYHFEEAKYQDI
                     PNFSELSETEDFEIIPRIEKQEGQK"
     gene            22966..23067
                     /locus_tag="VQU30_000815"
                     /pseudo
     CDS             22966..23067
                     /locus_tag="VQU30_000815"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000234126.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="prepilin peptidase"
     gene            complement(23039..23815)
                     /locus_tag="VQU30_000816"
     CDS             complement(23039..23815)
                     /locus_tag="VQU30_000816"
                     /EC_number="4.2.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397537.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tryptophan synthase subunit alpha"
                     /protein_id="HET2446953.1"
                     /translation="MPKTLTKKLNAIKAAGKGIFVPYIMAGDHEKGLDGLAETIHFLE
                     DLGVSAIEVGIPFSDPVADGPVIEEAGLRSLAHGTSTQALVETLKTIETEIPLVIMTY
                     FNPLFQYGVENFVKDLADTAVKGLIIPDLPHEHANFVEPFLADTDIALIPLVSLTTGI
                     ERQKELIEGAEGFVYAVAINGVTGKSGNYRADLDKHLAQLHQVADIPVLTGFGVSSQA
                     DLERFNAVSDGVIVGSKIVKALHQGEPIQDFIKQAVAYQK"
     gene            complement(23808..25031)
                     /gene="trpB"
                     /locus_tag="VQU30_000817"
     CDS             complement(23808..25031)
                     /gene="trpB"
                     /locus_tag="VQU30_000817"
                     /EC_number="4.2.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000331289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tryptophan synthase subunit beta"
                     /protein_id="HET2446954.1"
                     /translation="MAYQEPNKDGFYGKFGGRFVPETLMTAVLELEKAYRESQADPSF
                     QEELNQLLRQYVGRETPLYYAKNLTQHIGGAKIYLKREDLNHTGAHKINNALGQVWLA
                     KRMGKKKIIAETGAGQHGVATATAAALFNMECTIYMGEEDVKRQALNVFRMELLGAKV
                     EAVTDGSRVLKDAVNAALRSWVANIDDTHYILGSALGPHPFPEIVRDFQSVIGREAKQ
                     QYRDLTGQNLPDALVACVGGGSNAIGLFHPFVEDESVAMYGAEAAGFGVDTEHHAATL
                     TKGRPGVLHGSLMDVLQDAHGQILEAFSISAGLDYPGIGPEHSHYHDIKRASYVPVTD
                     EEALEGFQLLSRVEGIIPALESSHAIAFAVKLAKELGPEKSMIVCLSGRGDKDVVQVK
                     DRLEADAAKKGEAHA"
     gene            complement(25009..25608)
                     /locus_tag="VQU30_000818"
     CDS             complement(25009..25608)
                     /locus_tag="VQU30_000818"
                     /EC_number="5.3.1.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000169895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylanthranilate isomerase"
                     /protein_id="HET2446955.1"
                     /translation="MTKVKICGLSTKEAVETAVSAGADYIGFVFAPSKRQVTLEEAAE
                     LAKLIPADVKKVGVFVSPSRVELLEAIDKVGLDLVQVHGQVAADLFENLPCASIQAVQ
                     VDGNGHVPNSQADYLLFDAPVAGSGQSFDWGQLDTTGLAQPFFIAGGLNEDNVVKAIQ
                     HFTPYAVDVSSGVETDGQKDHEKIRRFIERVKHGISGTK"
     gene            complement(25595..26362)
                     /gene="trpC"
                     /locus_tag="VQU30_000819"
     CDS             complement(25595..26362)
                     /gene="trpC"
                     /locus_tag="VQU30_000819"
                     /EC_number="4.1.1.48"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011227478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="indole-3-glycerol phosphate synthase TrpC"
                     /protein_id="HET2446956.1"
                     /translation="MSQEFLARILEQKAREVEQMKLEQIQPLRQTYRLAEFLKNHQDC
                     LQVIAEVKKASPSLGDINLDVDIVQQAQTYEENGAVMISVLTDEVFFKGHLDYLREIS
                     SQVEIPTLNKDFIIDEKQIIRARNTGATVILLIVAALSEERLKELYDYATELGLEVLV
                     ETHNLAELEVAHRLGAEIIGVNNRNLTTFEVDLQTSVDLAPYFEEGRYYISESAIFTG
                     QDAERLAPYFNGILVGTALMQAENVAQRIKELQIDKG"
     gene            complement(26359..27363)
                     /gene="trpD"
                     /locus_tag="VQU30_000820"
     CDS             complement(26359..27363)
                     /gene="trpD"
                     /locus_tag="VQU30_000820"
                     /EC_number="2.4.2.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anthranilate phosphoribosyltransferase"
                     /protein_id="HET2446957.1"
                     /translation="MKEIIEKLAKFENLSGVEMTDVIERIVTGRVTEAQIASLLLALK
                     MKGETPEERTAIAQVMRGHAQHIPTEIHDAMDNCGTGGDKSFSFNISTTAAFVLAGGG
                     IHMAKHGNRSISSKSGSADVLEALGINLDLKPAELGKVFDKTGIVFLFAKNMHPAMKY
                     IMPARLELGIPTIMNLTGPLIHPMALETQLLGISRPELLESTAQVLKNMGRKRAIVVA
                     GPEGLDEAGLNGTTKIALLENGEISLSSFTPEDLGMEDYAMEDIRGGNAQENAEILLS
                     VLKNEASPFLETTVLNAGLGFYANGKIDSIKEGVALARQVIARGKALEKLRLLQEYQK
                     "
     gene            complement(27374..27940)
                     /locus_tag="VQU30_000821"
     CDS             complement(27374..27940)
                     /locus_tag="VQU30_000821"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730493.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminodeoxychorismate/anthranilate synthase
                     component II"
                     /protein_id="HET2446958.1"
                     /translation="MILLIDNYDSFTYNLAQYIGNFAEVQVLRNDDSKLYEEAEKADG
                     LVFSPGPGWPVDAGKMEDMICDFAGKKPILGICLGHQAIAEVFGGKLGLAPKVMHGKQ
                     SNINFEAPSVLYQGIEDGRAVMRYHSILIEEMPEDFEVTARSTDDQAIMGIQHKNLPI
                     YGFQYHPESIGTPDGLSSIRNFIEKVVK"
     gene            complement(27937..29298)
                     /gene="trpE"
                     /locus_tag="VQU30_000822"
     CDS             complement(27937..29298)
                     /gene="trpE"
                     /locus_tag="VQU30_000822"
                     /EC_number="4.1.3.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398943.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anthranilate synthase component I"
                     /protein_id="HET2446959.1"
                     /translation="MERIIHGDVLSPILAYMRLKGQHKVILESIPRDKETARFSILAY
                     NPVFEIKFENGVLYQNGQAIDRDPLDFLYEVTHKSQHHSDLPFGGGAIGFVGYDMISL
                     YEEIGQIPEDTIGTPDMHFFVYESYMVFDHKKEKIHVIEDALYSERSQEALEKSLNQV
                     LEELRIPAPNEFEDLDLSPLDFKPHIAPHKFEGMVETARDLIRNGDMFQCVLSQRFSA
                     EVTGNPFDFYRNLRVTNPSNYLYFYDFGDYQIIGASPESLVSVKNGIVTTNPIAGTRP
                     RGATDEEDKALATDLLSDEKETAEHRMLVDLGRNDIGRISETASVQVTKYMEVELFRY
                     VMHLTSVVKGRLLAELTAMDALKATLPAGTVSGAPKIRAMRRIYELETEKRSVYAGAI
                     GYLSATGDMDLAIAIRTMILKNQRAYVQAGAGIVYDSIAQNEYQETINKAKSMTRIGE
                     LRP"
     gene            complement(29799..29876)
                     /locus_tag="VQU30_000823"
                     /pseudo
     CDS             complement(29799..29876)
                     /locus_tag="VQU30_000823"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002674100.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopuranose mutase"
     gene            complement(30481..31482)
                     /locus_tag="VQU30_000824"
     CDS             complement(30481..31482)
                     /locus_tag="VQU30_000824"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000789954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HET2446960.1"
                     /translation="MKNINGKKVTIYDIARLSGFSPKTVSRVINGGVNVKEETYQAIQ
                     KVIEELSYIPNAYAKNLTKKEAINILISVKKIDSFPLIWFHTLLDKVLRTCKEFGVNA
                     IVEYFGEEDTISNSIISSTGSLVDGVIVFYESVDDIRIQYLKKNHMPFLVFGESQTSG
                     VVYVSNNNFQATYDMMKAVTEEKFKNMWLLMGGESHVNKDRERGVRSFLNDKNYFMDL
                     KVIYGLSTIDSVYSYAMQHLTTQNYPDIIFVSGDEKVQGLIRACYEKGILIPDDISII
                     GFDNIPISQYYTPALSTIAPNYVKLAKEMIEGVLAIIKGESVTSVEVSPKFVRRQSF"
     gene            complement(31590..31958)
                     /locus_tag="VQU30_000825"
     CDS             complement(31590..31958)
                     /locus_tag="VQU30_000825"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001865040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2446961.1"
                     /translation="MKDYKINFDLGKIEYFDNNCLIQVYKFISFYDICEMVFAFHLPP
                     DELITNVIFKEKINSMLKCYIDRLLYVFINPTHFTEKVNLQFYGSFFSYEFICREVGN
                     ILKNKGVKCNLNFFEGEEYL"
     gene            complement(32054..32764)
                     /locus_tag="VQU30_000826"
     CDS             complement(32054..32764)
                     /locus_tag="VQU30_000826"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000127555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MgtC/SapB family protein"
                     /protein_id="HET2446962.1"
                     /translation="MTATSLGLSNIEIVVRIVLSVVIGSIIGLERGSKSQPAGIRTYS
                     IVCLAACLIMMTNEYVSYKFGTGDPTRLGAQVISGVGFLGAGTILITDKKKITGLTTA
                     AGIWASAGIGLAIGVGFYEGALLVAISVWGVISMFQPLKKYLQNRSKMIELYIVVKST
                     EAYNRVLVYCAENGIRMTDSRTAFGDVNSDRIEYFDVPDKKIASFITLELSGRFEHLR
                     LMEEIANIVGVIYVEEIS"
     gene            complement(32767..34458)
                     /locus_tag="VQU30_000827"
     CDS             complement(32767..34458)
                     /locus_tag="VQU30_000827"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001861837.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron ABC transporter permease"
                     /protein_id="HET2446963.1"
                     /translation="MRHKLNLKDWLIRLGLIWFLVTFIIYPNFDLVVNVFVKGGEFSL
                     DAVHRVLKSQRALQSIMNSFKLAFSLIITVNVVGILCVLFTEYFDIKGAKILKLGYMT
                     SLIYGGVVLATGYKFVYGPYGLITKFLQNVIPSLDPNWFIGYGAVLFIMTFSGTANHT
                     LFLTNTIRSVDYHTIEAARNMGAKPFTVFRKVVLPTLIPTLFALTIMVFLSGLSAVAA
                     PMIVGGKEFQTINPMIITFAGMGNSRDLAALLAIILGIATTILLTIMNKIEKGGNYIS
                     ISKTKAPLKKQKIASKPWNIIAHIVAYGLFTVFMLPLIFIVLYSFTDPVAIQTGNLTL
                     SNFTLENYRLFFSNSAAFSPFLVSFIYSIIAATTATILAVVFARVVRKHKSRFDFLFE
                     YGALLPWLLPSTLLAVSLLFTFNQPQFLVLNQILVGSLVILLIAYIVVKIPFSYRMVR
                     AILFSVDDEMEDAARSMGASPFYTMMKVIIPFILPVVLSVIALNFNSLLTDFDLSVFL
                     YHPLAQPLGITIRSAGDETATSNAQALVFVYTIVLMIISGTVLYFTQRPGRKVRK"
     gene            complement(34470..35480)
                     /locus_tag="VQU30_000828"
     CDS             complement(34470..35480)
                     /locus_tag="VQU30_000828"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001847714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET2446964.1"
                     /translation="MIKFDNIQIKYGDFVAIDNLNLDIHEGEFFTFLGPSGCGKSTTL
                     RALVGFLDPSSGSIEVNGTDVTHLEPEKRGIGIVFQSYALFPTMTVFDNIAFGLKVKK
                     VAPDVIKAKVSAVAAKIKISDQQLQRNVSELSGGQQQRVALARALVLEPKILCLDEPL
                     SNLDAKLRVDLRKELKRLQKELGITTLYVTHDQEEALTLSDRIAVFNNGYIEQVGTPV
                     EIYHNSQTEFVCDFIGDINVLTDETVHEVLLKNTSVFLEDKKGYIRLEKVRFNRETEQ
                     DFILKGTIIDVEFSGVTIHYTIKVSESQILNVTSIDSQAAIRSVGESVELFITPSDVL
                     QF"
     gene            complement(35583..36650)
                     /locus_tag="VQU30_000829"
     CDS             complement(35583..36650)
                     /locus_tag="VQU30_000829"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000738359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HET2446965.1"
                     /translation="MKKMKVWSTVLATGVALTTLAACSGGSNSTTASSSEEKADKSQE
                     LVIYSNSVSNGRGDWLTAKAKEAGFNIKMVDIAGAQLADRVIAEKNNAVADMVFGIGA
                     VDSNKIRDQKLLVQYKPKWLDKIDQSLSDKDNYYNPVIVQPLVLIGAPDVKEMPKDWT
                     ELGSKYKGKYSIYGLQGGTGRAILASILVRYLDEKGDLGVSEKGWEVAKEYFANAYTL
                     QKGESSVVKALDKESPIQYGMIWGSGALIGQKEQNVEFKVMTPEIGVPFVTEQTMVLS
                     TSKKQALAKEFIDWFGQSEIQVEYSKKFGSIPANKDALKELPEDTKKFVDQVKPQNID
                     WEAVGKHLDEWVEKAELEYVK"
     gene            complement(36675..37334)
                     /locus_tag="VQU30_000830"
     CDS             complement(36675..37334)
                     /locus_tag="VQU30_000830"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000793810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1868 domain-containing protein"
                     /protein_id="HET2446966.1"
                     /translation="MKNLTKIKFKENGEFNHFPGNTVVANLYTKQDLMEVVDIIQSRY
                     RELPFIDKFTLTPRNSIHMTVIELLCHENRETEFWSSNLPLDTPLQEIHDYFAKQLEI
                     FPLLDEEIHMRITEMGKQNILVEPADEASAKRLEEIRTYVSEKAGVCFPNHDRYQFHI
                     SIGYLRIPLTEEEEEEFTKVRAELTEILLEKIPTITVNRIDYTVFEDMRQFVPYHEKF
                     K"
BASE COUNT        12046 a         7633 c         5730 g        12043 t
ORIGIN      
        1 gtacaccata gtaattgttg agtttaatgg gccaccttgc gtcataacca ttggttgtac
       61 aatcagctta aaagcagaaa ttaaagttgt taacaataca aacagggctg ttggttttag
      121 taggggcatc gtgatataac gaaactgagc ccattttgag aatccatcta attcagcagc
      181 ttcatagaca tcttgtggaa tattctgcat tcctcctaaa aataaaagca tctgataacc
      241 tgcaccctgc caagcagaaa caaaaacaat tgcatacata gcttgtttag gactagtcaa
      301 gaaaggttga gaagcaatac ctaccttatt taaaatagca tttaataagc cactatttgg
      361 atttaaaaga taaagccaaa gaatagaaat aactaccaag gacatgacaa ctggagcaaa
      421 aaaagccact ttaaaaaaca tatttccttt tcgcttttta ttgacaatca aagccattcc
      481 taaggccgct cccaattgaa ctggaataat ccaaacaaca aatttcaaag tattcaagaa
      541 gctctttaag aaaatcggat cttttgttaa tcgaataaaa ttttcaagtc caacaaattt
      601 tctttcatct ggtgtcaaca aataataatc tgtaaaagcg taataaatga ccattccaac
      661 tggaattact aaaaagatac ctaataaaat taaagctgga gctaaaaaac tataacctaa
      721 tatgttatcc tttatttttt cacgtctttt tgtatacaca acagtttctt tactcatatc
      781 catctccttt aatcatatat atcaaactag gctattaaca agaaagggga aggtagttcc
      841 aaacattttc cttccacctt cttttttaca gattatttga gtgactgatc aatagcagtt
      901 tgcatttctt ttgtacgagt atccaagact ttttgcacat ttggattttc ttcataatag
      961 ctaatatctt gcattgcttg ttgaaaagct cgagaaacct gaggatatgc tacgacaact
     1021 gggcgagcat gagctgtttt tgaattttgt tccatcaaga aacgcattgg ttcggatact
     1081 ttatctttga tattttcaat tgtagattta cgaattggaa ggaccgaatt ccccaagcta
     1141 ataatttcac ttgattctgt atttgtagca aatttaacaa attcagatgc ggcctctttt
     1201 ttatcagatt ttgtcgtcac agctaattgc caactacctg aaggggatac taattttttc
     1261 gtcttactag atactgggta aggaaggata ccaaaatcaa tatctttgta gtttgtattc
     1321 atgtcagcaa tcgtccaaga accactcaaa agcattggat actctcctgt ttcaaaacct
     1381 ttttcgactg gactaacagt tgtatagcct tcttttacaa gattttgaat gaattgaact
     1441 gcttctacac tctctttgga gttgaagtat ccttctgcct ttgttccatc ttcgtttacg
     1501 acagaaccat tatttgacca aatcaacggc atataagcat atggcaacat ttcatcgttt
     1561 gaattaatac gaaaatcaat tgctggtttg ttataatgat ctttcaattt tttagcaatc
     1621 gtattaaatt cgtcccatgt ccatggcttt tctagcgttg gaagctctga ttccgcaatt
     1681 ccagcctctt tgaacatttt tttattgtaa taaacaccaa cattcgattc agaaaatcca
     1741 aatgcataga atttcccatt ataagttccc tgttgtttaa tactgtccaa aacatcatcc
     1801 atattattat cttttagata atcatctagc ggagtaatta ctttagattt tgcataagct
     1861 gccgtatttg gtccatcaag ggtaataaca tctggaagac tattagtcgt aatagcagca
     1921 ttaaccttgt cttcatatcc tccaccacta ccactacgag gaatatactc agttacaacc
     1981 ttgtacttac tttttcctga ttgattaaag ttatcaacaa ctttttgcca agcttttcct
     2041 tcatttgttt cgtcagagaa ttgtacccag actttaatat catttgaaga actcgcttgt
     2101 tttgagttag ttcctccact acaacctgca agtatagcta acgatagccc cgcaacaaca
     2161 gataacattg tacctttacg catcattttt ctcctttttg aaacgtttca ttttttattt
     2221 attttttaaa caagcttcta gcctattttt gaaacgtttc atttgttgat tatattataa
     2281 cagcgctttc attaattgtc aagcgctttt taaatttttt ttgttgtttt atctccccca
     2341 aaatatgtgg gaattacgat tcgtttttct agaatctctt ctcgcttaat cattttcagt
     2401 atcattgcaa cagattcttt tgccatcata ccaatatctt gaactattgt agacactaga
     2461 taagattgat cgacagaagt ttttaaacca tcaaacccaa ttatctggta atcatcaggt
     2521 gctattttcc ccagttcttt cataacacta ataactctca gagccatcat atcatttatt
     2581 gtaaatatac catcaatttc tttatgagat tgcaaaaaaa ttcttatctg atcttcagga
     2641 tttattaaag gttctttcat ttcaaaatta tagacatcta ctcctaattc cttagctttt
     2701 tctctgaatc ctttacttct gagtatagtc tcattctcat acatattaat tgaaccaata
     2761 aaagcaaggt gcttattatc ccttctaacc agttcctctg ctgcagtttg tcctcctttg
     2821 taatttgctg aagtaacata gcatacattt tccgaaaaat gtctatctat acttacaaac
     2881 ggtaaatcag ataaaatata tttgtcaata tcagaatatg taataccaat aattccatcc
     2941 actttatttt gtttcaacat ttcgatatat tcgatttcat tttgtgaatc gctatcagcg
     3001 ttacaaataa ataatttata attatatttt aataactctt tctcaacatg ataggcaaac
     3061 tccgaaaaaa atggatgcca tatgctcgga ataatcaaag cgatagtttc tgttctattc
     3121 tttttcatac ctcgagcata attatcaggg atatagtcca atgtttttat agccctttga
     3181 actttcctta aagttacttc tttaatgcct ttttctttat taattacacg tgaaacagtt
     3241 ccaacactaa ctcctgcttc taaagcaaca tctttcatgg taattgattt tctttgttct
     3301 accatattat cacctccttt caatatatag tatcatgcaa atgcttttta agcaactatt
     3361 tctcaatcat ttttggccag atcatttatc ccatcatgaa taaaatcact ccaattagct
     3421 tttgaaaata cttcaatttt catgtgtaaa catctacata aaacaggaaa agccttggtt
     3481 ttatggcttt tttcgtatct tctacaaaaa aagcaagagt tttagagggc tataaatcta
     3541 gatgtacatt ttgcttaaat gattgaaggt cttttcttaa caaaaacacc ccaaaaatta
     3601 gattttttct gtctaacttt tgaggtacag ttcaaacgcg aaatagcgtt tttttgttat
     3661 ttttggttac tcatctaatc gaataaacat catggcattt aacaaatata tgagtgagac
     3721 cgtgtttata ttatttgaat agatgagtct cttattttca ataggaggaa taataaaatt
     3781 agaaataatg atatcataag atgaatcttc taaagattcc tttgataatt ctaattcagt
     3841 ccaaacttcc agttcaaaat tattgctaca gtaataagaa agtgtctctg caacgaattt
     3901 tgcatgatac tgatcaaaat tactcataac caaaaccttt agtttaggct gattttgtag
     3961 caaattaatc accaaatgtt tggtatgagt gatgaaggta taagatagat gatttaccat
     4021 cattgaacta gaacaaacct caagagtctc taaatagtga gaaagctctt tttttatatc
     4081 tgaaacaaat tttggaaaaa tattttgaaa gttcctgatt gtattccctt tttgatcaaa
     4141 taaaataaac tcagtaaaca actcttgacg atacagatgt gcggtattat gcagatgcca
     4201 aatcagatta tccttattct ccatttcaat ctgatacttg actgaaatct gatcaataaa
     4261 atcactcaat agatggtaag atttttcaac ataactatcc ttttttacgc atttcataaa
     4321 gagactttca tctatgaaaa acattttttg aaagtaagac acaaataatt ggcaaacaac
     4381 ttcttcatct aaagagatat tgtattctga ttcaaaactc tgagcaacac cttctattcc
     4441 ttctgcctgc attaaaaaat ccaaactttg gtcgttaaaa gaatctttat ctacttccat
     4501 aaaatgacca aactttattc tatataggtt cgtaactagg agcaacttta gcattctatg
     4561 cgttgacaaa ttcattggaa agcttgtttc cttataaacc aattctaaca attgagatag
     4621 tggctctgat gaaaaatttt caaatggcca ttctaggaaa taatattttt ctgaaaaata
     4681 ttgtgcaaaa aagtaacgaa tgtctctctc atttccaatg atttgaacag gggtcagact
     4741 gacttcaaat tgaaattgcc ttttaatcac tttattgatt tggctaataa tacgatagag
     4801 cgaagatgaa ctgatataaa attctttaca aatactctca gcttgacaac cttcattaaa
     4861 gaagatgaat tctaaaatcg aaaaatgagt tgaatgttta aagaaatgat ggtaaaccat
     4921 ttcaatatca ctatcatcgg tattaataat gcgtatacca ttagtagaag aatgaaaaat
     4981 caagtcagga aaagcagatt taacatggga tagatcatct ttgactgcac gttctgtaca
     5041 atttaataac tctgctagtt cagaacgatg aaaccaacgt ttatgttcaa ataataattc
     5101 taataattct aattgcctat gacttttttt agataataaa tctctcatga atatctttct
     5161 ctctttataa attatcggat taaacctctt gcaattatac cacaaagaat aggtatagca
     5221 tgatataacg acttttccta aaatctttta tttcgtataa taacactacg gagacaatat
     5281 ataaacaatt ttcttatttt accgtctatt gagggcgtga atacagaatc aaattcaagt
     5341 ctaaagatta tatttttaat tttaaaaatt atataatagc aacaattaaa gaatttgatt
     5401 ttttaaaatt atataataat aacaatcgaa ataattgact tttctatatt aaagttatat
     5461 aatagtatta atcaaagaaa ttgatttttt gatattaaaa taaaaaagga gggtaggcag
     5521 tgttgtgatc aattattgct ggaggtctta ttggtctctt ggcaggtaaa atcactaaaa
     5581 aagtagttct atgggaatca tcgcaaatgt attcgctggt ttagtcgggg catatgcagg
     5641 acaatctctt ttaggtagtt ggggtccatc aatcgctgga atggctttgc tcccatctat
     5701 tgtaggtgca gcgattgtga ttactgtagt gtcattcttt acaggtagaa agtaaacttt
     5761 tcgccagtaa agttagcaaa ctatttttaa atcaatgacg ggaaaaatag tttaaatgtt
     5821 aaatcgaaag gattgtatat gtcaaaagca aagaaaatat gtttcattat tttctgtatt
     5881 ttaatcttga caattttcct tcctgttttg atagattatc atcaagttag tgatctaggt
     5941 attcatctac ttagctggag acagaactcc gtagttgaat tctatcttgc tagatatgtc
     6001 ttttggggga cagtggttct atcaacttta gttttattat ccattttagt tgtgatgttt
     6061 tatcctaaac gttacttgga aatccaactt gaaactaaaa acgatacatt aaaattaaag
     6121 aattcggcaa tcgaaggttt tgttagaagt ttggtgagtg atcatagatt gatcaagaac
     6181 ccaactgttc atgtaaattt acgaaaaaat aaatgtttcg ttcatgtaga aggtaaaatt
     6241 cttccttcag acaacatcgc tgacagatgc caaataattc aaaatgaaat aactaatgga
     6301 ttgaagcagt tttttggtat tgagcgtcaa gtaaaacttg aagttgcagt aaaaaattac
     6361 caaccaaaac ctcaaaacaa aaagactgtt agtcgtgtga agtaaggaag taaaaaatgg
     6421 aatggcttaa acaatatcga tatccaatta tcgctggtct cataggcgta tttctggctt
     6481 gtttgattgt ctcctttggc ttcttcaaaa caatatttgt attgatttta ggagcactgg
     6541 gagttgcagc tggattatat atcgaaaaaa actatataga taaataaaaa aataaaaatt
     6601 actaatttaa ttaaaggagt ttcatatgtc aaacgaaaaa aacacaaata ctaacgtaga
     6661 aaagaaagat gctactgttg tagctcacga aatcaaaggg gaacttactt acgaagataa
     6721 agttatccaa aaaatcattg gtctttcact agaaaacgtt tcaggtcttt tgggaatcga
     6781 tggtggtttc ttctcaaatc ttaaagaaaa aatcgttaac agcgatgacg taacaagtgg
     6841 tgttaacgta gaagttggta aaacacaagt tgcagttgac ttaaacgtta ttgttgagta
     6901 ccaaaaaaat gttccagctt tatattcaga aatcagagaa atcgtatctt cagaagttgc
     6961 taaaatgact gacttggaaa ttgttgaaat caacgtaaac gttgtcgaca tcaaaactaa
     7021 agaacagcat gaagcagact cagtaagcct tcaagatcgc gtatctgacg ttgctgaatc
     7081 aacaggagaa ttcacttcag aacaattcga aaaagctaaa tctggtcttg gatctggttt
     7141 ctcaactgtt caagaaaaag ttagcgaagg tgtagaagct gttaaaggtg cagcaaatgg
     7201 tgtagtatct cacgaaaaca ctcgtgtaaa ctaagataaa ataaatataa caggagaaat
     7261 tatcatgtca gtagaagaaa aattaaatca agctaaaggt tctattaaag aaggtgttgg
     7321 gaaagccatc ggtgatgaaa aaatggaaaa agaaggagca gctgaaaaag ttgtttctaa
     7381 agtaaaagaa gttgccgaag acgctaaaga cgctgtagaa ggtgctgtag aaggtgttaa
     7441 aaacatgttg agtggcgatg ataaataagg ttaaaagtta ctttatcttt ttggtaacat
     7501 tagtcaaaag agtctgagtc aagatgattc tcagaaaaca aaaagctaga gattcccaat
     7561 tgcggaactc tagcttttta attttgcctc tttctcttat tatatttcag caggttgttg
     7621 gccatgagta tgaatcccat gtcaattctc acttgacgct tacctctcag atgacatctc
     7681 ttataaccca aacaaacctt tatctgccca aagacagatt tcatatcaat cttacgttta
     7741 gcgaaaattt gtctaccctt ggaagataaa agtgcctgat attctttagt ttttaaacac
     7801 tggtaacgtt cattcatata cagtcccttt tgaggggctg attcaggttc ataatcgcag
     7861 tcaacattga tttcaaggct gtttgctttc tatctcccct ttttcatgat atattttcgt
     7921 acaggttctt caatagtttc tatagtaaaa tgaaccaaaa atagtacacg ttgcggtata
     7981 atgttcttgt ggcatattca ttagattttc gtaaacagtt ctctcctatt tgtgagcgaa
     8041 caagtatagt caattgattg tcagtttgaa gaccaagagt cgtaaggcaa aggatatggc
     8101 agaatccatc caagggtggc tggcacaatt tctagtgaac ctctttaaat ctattacgtt
     8161 tgactgtgga aaagagtttt caaaatggaa agatatttcc aatcatcacg atagtgagag
     8221 cttttttgcg aatctaggat gttcaagaca gcggcgtctc aacgaacatt caaatagact
     8281 tttaaggtgt catgacttgc caaagcagac agatttcaac gaagtcagtc aagaatttta
     8341 ggctggacaa aaactcaatt tcaggagaaa atgaaataaa tattcccaca ataaaacgca
     8401 tagtatcaaa gtttttccaa cacctgatat tatgcatttt ttaattttaa agactttttc
     8461 ccagcctcaa gaaatcacat cccacctaaa tcctttggat accaaatacc tcatcaggta
     8521 ttttctgagt tggtaagaat gtctagctta atttgacaaa tggagggcgt taaatccagt
     8581 ttttacagga agtctattta aatattttca cactgacctt acaaaatatg aaataaatta
     8641 tataaagtca ttcccatgac aaagaataac atccctttaa aacagtatct tacccaattt
     8701 tcaggtaaga cttttgatac aaccgtcccc aatacccctc cgcatataga agcaagaaaa
     8761 ataactggaa caggtgctaa atgatactga tttaaacctg taaccacaac aattgtagcc
     8821 aaatgagaca gctgggaaaa gaaaataatt gcaagagaat acatcgttgc ttcttttatc
     8881 gaaatagaaa aaaacaccat caataaagat acattgagcg gaccaccacc aatccctaaa
     8941 aaactagaaa ttaagcccaa tagaagacca caaatcatat agaatcctat cttatcaaat
     9001 tgataagttt ttttaaaatc tgttaaaaca aatgatacaa gtagcatcac aaatagtaaa
     9061 atcatttgaa caatggatac tagccgtact gataactgag ataacaaaac ttgaaaaata
     9121 agatgaccta gaaatcctcc taaaacagaa gaaaaggata ccgtaaaaat caatctccat
     9181 tttatctctt tactttgtga aaatcttttg attgttgaaa taatcgccat tataaaaaca
     9241 gagaaactag aataaaaagc aatatcactg accgaatggt atccaaaact atccataagt
     9301 ggcttaatta taattccacc acccatgcct gatatagaac ccaatccact agctattata
     9361 atgattagaa aataaataat ctcaaccact ttttaagtcc atcctattct ttcaaacatc
     9421 taaaacctag atggctacta gtggaagtag agatacatcc atttctagca gctactcggt
     9481 atcgattaca ataagaacaa tgacataaaa aggaacctcc tctgatagca tactcctcat
     9541 cttgtatccc atattttggc aactcatagt catcttcatt aaaactagct aataaggtat
     9601 atctcggatt gcgacaccat tcccaaacat tcccaatcat ttgatataga ccaaaatcat
     9661 taggtaaaaa ttcatagaca ggagccgttc ctataaatct atctaaggca gtattttcat
     9721 aaggaaatct tccttgccaa gtattggcat gataatatcc accttctaaa agagtatctc
     9781 cccaaggata ttcagattgt cttcctcctc tagcagcata ttcccactgt gcttcagtag
     9841 gtaaagacat tccgctccaa ttacagaaag ccaatgcatc ttctaaagca acatgaacta
     9901 ctggatggtc ttctaaaccc actagattac tgttctcacc gtagggatgt ttccagcaag
     9961 cgttcggaac ttgtaaccac cacggagccc cagcaggatg aggatatccc tccctttctg
    10021 cctctggaac gaacaatata aaaacaaaag accactcttg tcgctcagct agtgttttat
    10081 agcctgtttc tttcacaaat tgagcaaatt cttgattcgt aactggagta tccgcaatgg
    10141 aaaaatcctt tacactaaca gcgacttgag gaccttcaaa atcatctaaa aagccctctt
    10201 cagaatttgt tcccatcata aatgtcccac ccttgatttt tttcattttc atgattgact
    10261 atcccccgtt ttcgttagag ttggcgttat tttagaaagt tcaacaggaa ctaactcttc
    10321 atccacaaca aaaccttctt ctctatatct aagaaagtct actaattttt tcttcatctg
    10381 acgaacaata ggttggtatt tttcgcttgg atacaaatca ttcatttcat gcggatcttt
    10441 tttcatatca aataactgat aatgatttaa aacaggaaac cagataaatt tccactggtc
    10501 tgtcaagata tattgactag aatcttttcc taaagcatgt tcaccatgaa attctgttcg
    10561 ccacccctcg tactgtccaa ataataaatt cttaacactc cgtccatcta gttcatctgt
    10621 agtagttcct cctgccaaat ccacgagtga aggaaaaata tcttgaattt tcactaattg
    10681 cttgattgtt cccctattac cagctatcaa tccagccgga tcgtaaataa acgaaggaat
    10741 gtggatactt ccctgataag gatatccctt tctaaacaga taatgttcac caagctgatc
    10801 tccatgatcc gaaacaaacc agataatcgt atctttatca tgacgaaatt cttttaggga
    10861 agtcaaaaag cgactaattt gatggtctat atgagtaatc aatccaaaat aagcagcaac
    10921 cattcttctt tgatcatctt cctttaattt ccctcttaaa gcataaatag acggaatttg
    10981 cttttctaat acttcccaat tcccgatatg caaatcgaga aattgaggca agcgttccat
    11041 atacatatca aaatagtatt ttgggggatt taatggagca tgtggttttt caaaagacat
    11101 tttgagaaaa aaaggaaccg ttggatctct tctttgtaaa aatgaaatgg actcactcac
    11161 aacccagttt gttggatgta acttctcatc tttatcccaa ggtctagctt cccaagaatt
    11221 acaatccatt ccgtcatcaa tcaaatcaac atcataacca actttaccct ttaaaaaggc
    11281 tagatagtca ctaacataat caaattgact tccataagcc ttatcatact ttctatcaac
    11341 atgtagatac ccatcgtgaa gtaagacatg atcaaaccca agtctctgtc tggaaggaaa
    11401 aacatgcatc ttaccaatac actctgtttg ataacccata tctttaaaga cttttggaag
    11461 agtattagta aaattccaag gcacctcatc ttgataacca acacgtccac ttttatcttg
    11521 gtctaagcca gtcaataaag ctgccctagc aggaacgcaa gaaggaactg gagaataggc
    11581 attttcaaaa ttataaccta cactagccat catatctaat gttggagtgc taactagctt
    11641 atccttacta ttcaaggata aggcgtctgc tctcatttga tctacaacaa tcaaaataat
    11701 atttggctgt tttgtctgaa ccataaaatc tcctttctaa tatggcaaaa gaggcacaag
    11761 aagatatcta cctttactgc acccctttct atatcaatct ctctatataa agcaataaca
    11821 ttcttgttat gttttataga acaatgaact aaaatatgac taaatcgatt aggaaattca
    11881 aatcattttc tagtactgtt ttagaagtta cagtgtacta ttccaacttc aacaaactat
    11941 aaaccttggt ctaataacaa ttttagtgga gataagaaat cctacaccta actcatctta
    12001 cacgtaatct atttctattt tatcacaaaa aacgcaagta agaccattaa ctcaattcag
    12061 ttttatctgc cattttcaca aatgggaaat aagtcaagac actaataatc aaacaaacaa
    12121 ctgataagat gatggcacgc caatcaaatg ctgtagagaa gaaaccatat aaaattggag
    12181 gcattaccca agtaacattt tgtgtaacag gtgaaacaag accccagctt gttgcccagt
    12241 aagctaccgt tgccatgaaa accgggctaa gtacaaatgg tataaatagc aaaggattca
    12301 agacaactgg taaaccataa ttgaccggct caccaatatt aaacagaact ggtgctagac
    12361 caagtttagc aacttttcga taatgactgt ttcttgaaaa aattaaaata gcaagtacca
    12421 atcctaatcc tccaaaccag acaaacgccc caaaagaccc acttgtccat atataaggaa
    12481 tcggttcacc tttttggaaa gcatccagat tcgctaacat agcaactcca aacagccctt
    12541 ccatgatggg agccaataca tttcctccat ggagaccaaa aaaccagaat aacttattta
    12601 aaaagatcat cagaataact gcaaagaaac tttgagacaa acctagtaat ggcgtttgta
    12661 acaccttgta aacccaatca atcaataagt cattgctaag taaatggaaa acataagtca
    12721 agatggctac tatatacatc gccataaatc ctggaatgat agaagtgaac ggcttagcaa
    12781 tcgcaggggg aactgaatct ggtaacttga ttacccagtt ctttttcatt actttacaga
    12841 aaataataga ggctaaaaat ccaatcatca tggctgtaaa gtagcctctg gcattaatat
    12901 ggtttcctgg aatcacattc ccaatagtta ccatcagatt tttaccatca aatgctagat
    12961 tatcaattcc ttgtaagatc tgatctaatt tcacatctcc tacatttgcc aaagggaaac
    13021 tctttgtaac tgtacttcca atcgaaatga caaacgaagc aagtgatacc aaaccagcag
    13081 aaactgtatc aaccttgtaa atcttagcga tattcactcc caagcaatag atgaacaaca
    13141 aagaaacaat tggtatactt cccttgaata ccaaattatt gatgtcaaca agccactgaa
    13201 aggttttcgt aatactttct aggtgaaatt gttgtggtaa atccactaga aaagcattta
    13261 ataacaaagc aatggaacct gtcataataa caggcatagt ccccacaaat gaatcacgta
    13321 aagcaactaa aaacttctga ttcccaactt tcattgcaat tggagaaagt ttttcttgca
    13381 ttttatccaa cattgtattc atactaaact cctaattttt ttcaaatcgt tcgtatactt
    13441 ctaccacttc tttcgccaag tcaacaaaag tcagactcgt cattaaatga tcttgcgcgt
    13501 gtaccatcaa gaggctaatt gatgtttctt ccccctgtgc ctctcttgtc aacatttctg
    13561 tttgagcctt atgcgcctgt aataaggcag cattcgcatc agctaatctt cgattggctt
    13621 tagagaaatc cccttttttt gctgcctgaa tagcctccat agcattactt ttggcttccc
    13681 caccatacat aattagcccc attacagatt ctaaattact ttcatccata acattctcct
    13741 caatcttagt ctaataaact ttcagctaaa tctaaaactt tagaaccatt catcattccg
    13801 taatctgtca tcggaataac cgccacagga atctgtctat cttttagttt ttcttgaaag
    13861 tcccctagta aatagcgaac ttgggggcct aaaagcaaca catttacttc ttttgttgct
    13921 acaatttctt ctgcttcagg agctggaact gcaaaaattt ctgcatccaa ccccttatct
    13981 tctgctgcct tttgcatctt tgtcactagc agacttgtac tcatacctgc tgcacacgct
    14041 aacataattg ttactttagc catagcttac tccttttatt ttattgtcaa tgttactgtt
    14101 tttcgatcaa ctttagactc ataatctaaa tgtttgggac gactagtata atgcaaatta
    14161 taaactcctg gaggcatttg tgaaatcttt tctttttcag ttttattgcg aattaataaa
    14221 tctaccgaag tattccctcc aaagttatta aacataggtt cattttcaat agaataatct
    14281 aactcatatc cactattagt tgtaattcct tttaataaat caggaacatc tcctctgttt
    14341 attactatat ccttagcgcc atttattttg ggagattgac tataatactc ttcagcttga
    14401 tgttgttgta aatcatttct agagtaagaa acataatcaa ctacaaattc agtccctgat
    14461 aaattattgt ccactacccc aggccaactt cctcccatcg ctaaatttaa ctgaacatac
    14521 tgaggtctat taaaaatctt tttcgctata ttatctgatc cataatatac ttttctaaca
    14581 atatgattgt caaccatcca tacaatataa tctttatacc aatcaattga aaaagtatga
    14641 tacgaatcat taaagtttcc actcgataat ttaaaggctg taccacgtcc tgcaaatttt
    14701 ccatcatcat tatccgactg tccataatga agcgtttgat aaactgtctt attcccactt
    14761 ccatttgaat ttcgttcacc aactaattcc attatatcta tctcacctgt tgacggccat
    14821 cctcgtccct gaacaggatt aatcttccca tcaagtgtaa aatccgatcc aagagtccag
    14881 aaagcaggaa aaactccttg acctttcggt aattttgcac gcatctctaa tttaccataa
    14941 agaaattcta ctttcccatg tgttctaaca cttcctgaat tatatacaac ctttctgtga
    15001 ttgtttcttg ggttaaaata ctgatcttcc ttagagcgat tcgtagctct aagaactaaa
    15061 tttcccgaac gtagaaaaac attctcatca cttcttacat aatgttgctg ttcccaacca
    15121 cgaattgatc ctaattcata tccccaatat tttttattta attgttcgcc atcaaaatca
    15181 tctctccaaa ttttcttata tgaatttcct ttagacagtt gatacatctc tacattatca
    15241 ataaaaatat tagatttttt tgtagtatcg tcttctgacc atttcactaa ttgaatcaaa
    15301 actttatcgt gtttaccgga attgaaagaa aacatgtatt ttttccattc ggttgtatta
    15361 actgtttgat caacagcttc tccaatgtta ttttgaacaa tctctccttg cttattatta
    15421 tcaaaccatc ttgcggtaaa atatccctct gctccactaa tatctacttt ggcaaaagca
    15481 gatactaaat aatcttcatt aggttctata tcaataactt gtccaatata tccatctgct
    15541 ctattatcat taattgcagt agaaggaatc atacctgagt aatgtccgtt actataactc
    15601 tcatttgaat taattattcc cctatttcta gagttccaaa acagctctcc ttgctcaaaa
    15661 tttgaatttt ttattaaatt ttcattagca aaaactttca catgaataaa tattaataaa
    15721 aataatataa ataaacttga aattaatttc ttattcttca ttttatcacc tatttactga
    15781 cctagccaag cgagatactg tatgtctcac tcctctaatt gccttgctca atgcataaat
    15841 attatcgact gttgccagtc ccccatatcc tgcgtcacct atatgttgaa tatcaactcc
    15901 acaaatttta tttctaagtg caatttcctt gatagtatct gtatcagatg tttcttggct
    15961 agtaccaata gcactcagta ctagcccacc cttactatga acgagatcaa cgacttcacg
    16021 caactcttgg tcatgaaagg ctggaacggt tccaactgct ggaacaagta tcacatccgc
    16081 acctgcttcc aacaattgct ctgcgacaga aagctctgcc acaggctcat tcactcctgc
    16141 cccgtgcatc ttacctgcaa taatcaaacc agaaaagttt tccttagcag tttgaacagc
    16201 cttaatgatt tctcgattgc taactcctgt tccaggattt ccagtcaaac agacaaagtc
    16261 aaaacctaac tcctctattc gattcaatgt ttcaacacta gcaacacgac ctgcaacaat
    16321 ttcctgtgtt tcctctagca tctttgcaga tgggtcaatc ggttccaaat ttacaccaat
    16381 tggacaagca acaagctggt gtaagcgatg aataacatca tcacctgaac tatccaaagc
    16441 ataaatttta ggctcaaaaa catcaacaca attcaataaa atcatatcag ctccaaaagc
    16501 tctagcaatt tcagaattag ttatatcccc aacaaatgtc tcacgagtaa ctacattttc
    16561 agatagaaca actctacctt cacttgctaa aatactttgt tttaattctt cagcattcat
    16621 ctgtaatatc tcagatggat ttgcactaat taaacgtttc attctcaatc ctccaataac
    16681 ttaaaccgtt tttcaatagc tattacaaat ggtaaataaa gtaagacatc caaaacaatc
    16741 aatacaattt gtaataatga accagaaata cttcctgtag caagtaaacc acttataaca
    16801 ggtggcatag tccaacttgg atctgtataa gttagcggaa ccaaacctga tgccattgct
    16861 ccccacgcta ctagtaagtt aaacattgga gctaagataa atggaactag taacaaaatg
    16921 ttcaaaacaa taggaacgcc aaacattgct ggttcattta tattaaataa tccaggtata
    16981 acagttatag gtgccaaagt ttttagttgt ttactagctt tcttcttatg tgctaaatat
    17041 cctaacgcaa gaactaaacc tatggttgca ccaccgccac ctatgaatac aaaattatcc
    17101 ataaatacgc tagtaaaaat atttggaaga gtttctccag tttgataagc tactttattt
    17161 gcatctagat tagctaacca taacggtttc ataactgcat taacaacatt tcctccgtgt
    17221 aatcctacaa accaaaaact actattaagg aaaattaaga taagaagacc aataacatta
    17281 tttcctaaaa gtccaagtgg acctcccaaa gctccttgag caatttcatg aagattaggt
    17341 aaacttaatt tatctaaagt tgcataaaca atcaaccaac caacaatagt cactgcacca
    17401 ggaataatgg cactaaagct tttagatact gctggtggaa caccatccgg catttttatc
    17461 tgtatattat gatttataaa ccattggtag atatagccat taatcaatcc taaaatcata
    17521 gcaacaaata aaccttttga tgccatgaaa gcggtaggca ttcctgctcc agcctctcct
    17581 gtaatgaaag gcgtaactgt aataaaagat gataatgaca caataccagc aggaatacca
    17641 tcaactttgt attgtctagc cataaagtaa gcgataccaa aactagctac aagaccaagt
    17701 aatccaaaac tactatcaac acccttccat aaatagtcag caacaccaat atcacctaga
    17761 tatttttccc atcctggaat aggaaaactt gcaataacca ttagtaatga acctatcaac
    17821 aataaaggta tagttagagt aataccgtct cgaatagaaa ccaacgcttt attattaccc
    17881 aatctagccg ctactggaag taacttttct tgtaataatt tttccataac cttttcctct
    17941 taaatatatt ttattatcaa aagttatcaa ttatctttat tttttgacgt caagttatta
    18001 tttgattatc ttttgttatt tatattttac aactataaga aagccttgtc aaggatttgt
    18061 gtaaatattt gattattttt tattatcaat atataataaa aagagaccag taagcaatga
    18121 aaagcttaaa aagattaaca tctacattta tccatagcaa aaaatcatag gattttaaga
    18181 atctgacaac taggaagaaa actaatatga ccttatctaa gaaacaatta caactaagag
    18241 ctaaaatact ggaaacagtt tacacattag gtcccatttc acgaattgaa atcgctacta
    18301 aaacaggaat aacacctgca acaactagca gtatcacaaa tgatctgatt aaagaaaata
    18361 ttctcttaga acttggtgaa gacgaacacg atacaagcgt agggagaaaa aaaatcctgc
    18421 tagacattca agctaaacga ttttactaca ttggttgtga actatctgaa aaacatttca
    18481 cttttgcttt aggagataat ctaggaaata tcttaaagga agagaaagaa attgttacta
    18541 aacagttaat ccaagaaaag ggaaatcaac tcattaacca gacactaaag caattcttaa
    18601 ataactgctc tgattatgaa atagaagcaa ttggaatcgc gctacctggt cgctatttag
    18661 atgattataa aataacaaca aacaatcctt tatggcaaca tatcgactta gaaatgattc
    18721 aatcccactt tgataagcct ttgtttttct ctaacaatgt taactgtatg gctataggta
    18781 aacgcctatt tagtcgccaa cagaatgacc ctaattttgc ttattttcat tttgctagag
    18841 gtatgcactg ttcttatatc tacgacggaa acatttatgg gaaaggaaat ctaatgattg
    18901 gagaaatagg gcatacagtt gtttcatctg agggagaaga atgtagctgc gggcgcaagg
    18961 gatgcttaca aacttttgct ggagaatctt ggttaatcaa aaaatcaaaa attctatatc
    19021 atcaatctcc ctattctcta cttcctagtt tagtcaaaaa tgccgatgat attgatatcc
    19081 aagttatttt aaccgcttat caattaggtg acactggaat aatcacactt atccatcaag
    19141 ccttactcta tcttagtcaa accattttaa atatcagtat gatgattgac tctcaaaaaa
    19201 tctacctaca tagtccttta ctaacaaatc aacacatcat ccaaaaacta tatagtgaaa
    19261 tgaactacaa acccaaactg ctctataatc gcctacctga agtcattatt gaaccttaca
    19321 atgattttac agccgcacac tcagctattg cactttgttt gtatcataca attctacatt
    19381 cttaattttc tattacattt aataaatagg ctaaaaagag ggagtatatc ataaaaagcg
    19441 aataaacctg ttttctgaaa atcagaattc tgttttgttc gctttcttta tatttggaat
    19501 tatactccta tctccccttt ttcataatgt atagtgaaat gaaataataa caggacgaat
    19561 cgatcgggac agtcaaatcg atttctaaca atgttttaga aatagaggtg tactattcta
    19621 gtttcaatcc actatatttt cgtacaggtg cttcaaccat ttgaacgatt tcaaatcctt
    19681 ctttttggta aagattctga gctctttgat ttgcctcgaa gacatttaga gaaatactat
    19741 ctatatcttc attttcaaag gccaaactaa caaatttcct taaagcctgg ctacctaagt
    19801 cttgctcctg tttctggggg ttgataaaaa atctcccgat atgaagattg ctgtcttcta
    19861 gcctgatttt ctggataagt cccacaaact cttgttcatc aaagattgaa aagactcctt
    19921 ccaaggcttg aaggggcagt agaaaaggaa tccttggtcc catccattgt tcttgaaagg
    19981 atttgcctag ggagttggac cactggcata caaattgagc gttttctata ctcacctttt
    20041 cttcaaaacg aattgtcatc ttttcctcac catcttatct atgtttctcc attatactat
    20101 ttctcccatt ttttacgaat agataagtat gattgatttt tatttttttc tcgtcgggag
    20161 cattctcgct tcctttcttg gtttggtcat tgaccgtttt ccagagcaat ccattatcag
    20221 ttcagccagt cactgcgatt cctgtcagac tcccttgcgt cccttagatt tgattccgat
    20281 tctctcacag gtcttcaatc gctttcgctg tcgctactgc aaagttcgct atcctgtctg
    20341 gtatgccctc tttgaactag gcttaggact cctctttctg ctttactctt gggaattgct
    20401 ttccttgggg caagtcgtcc taatcaccgc tggtttgacc ttgggtatat acgactttca
    20461 ccatcaggaa tatcccttac tggtctggat gactttccac ctaatcctaa tagcttcctc
    20521 tggctggaat ctggtcatgg tctccttcct catacttgga attttggctc attttattga
    20581 tatccgcatg ggtgcagggg atttcctctt tttagcttct tgtgctctcg tctttagcgt
    20641 aacggagtta ctgatcttga ttcagttcgc ttctgcgacg ggtatcctgg cctttctcct
    20701 gcaaaagaaa aaggaaagac ttcctttcgt gcctttcctc ttacttgcta cttgtgtgat
    20761 tatttttggt aagctactac ttgtttgata aattccaatt tctgccatat gtactccatg
    20821 aaattatttc acagttaaat tataaattat ttcttttgta caaagggatg atgttatcaa
    20881 atcgatctgt tcttctatct tcttgatact gatcaaaaaa tttcatttcg actgaaaata
    20941 tttcgcttat aaactgtaaa cgaatacttt gtttagacat tatagtcgct agactgacta
    21001 gatgattact caaaacgacg tccagaatac tctttacttt gcttggtttt ttaacaaaaa
    21061 tttgatcatc caaaggttca atcattttgt aacctttttg cgcaatttga cgataaaagt
    21121 aagaatgttg ctttggagtc aataatccta acttaaaagc tcgatactct aaagcctgta
    21181 tcgaaacatt caaatccgac ttcaataaaa tataactatc aggattgctg acacgcttgc
    21241 caaccctctc ttcaaatttg actaaaaact cttcttttgg caataaaaaa catgatgcaa
    21301 aataatttgc ttcttgctcc aaacgatcgc catcttcatt catatcttta tatttatgta
    21361 aaagaatatg tcctagctca tgagctaaat caaaatttcg acgtacagat gatttattcg
    21421 ttcccaacac aatataaggt cttcccaatt ttgaccatgc gctataagca tcagcttggc
    21481 cattaattaa tcgttccacg atatagatgc ctgaacgttc taatttataa agcaaatcat
    21541 gattatcttt tgaaatacct aatttttccc tggcataaag agccaattcc tcaatggatt
    21601 ctcccttatg ataagattca ctcactacat tacttaggtc atgaattgta atattaggta
    21661 taattacaaa actttcaaaa taatcaatca aactatctac cttatgtaaa tacatagttt
    21721 gaatatctat tgttttccgg gttgctaggt ctgcatttct aaaggcaatt acagaagaat
    21781 caaatcgaat gctctcttct tcctgttcaa aataagttaa atcaacatga aattggttgg
    21841 ccaaatgcat tttggttgat aatttaggtt tcgtttcgtt ggactcaaac tgccaaatgg
    21901 cttgttccgt taaattaatt ctctgagcta attctgctct acttaaacca tttaacagcc
    21961 gtaattcttt caatacccga ccattaaaca tttacatact ccttactact tttgaccttc
    22021 ttgtttttct attcttggaa taatttcaaa atcttctgtt tccgataatt ctgaaaaatt
    22081 aggaatatct tgatatttag cttcttcgaa atggtacgaa cttgattgaa tatactcaga
    22141 caaatcttga atcaagtgta actgaccagt tcgtgcatca ggcataacaa catctacaga
    22201 tataatattg ttttctgagt ccgcctcata agttaaaatc ataaattttt cgatattcga
    22261 atttttagta gcttgttcaa tttcttgaat catttcatca gaaactaact ccatctgaat
    22321 tggaaaggaa tgactatctt catcattttt gtaggaagaa tgttgattaa gataaagtgt
    22381 attcatctga gcatattcaa ataagtagcc actcttattt ttttgtacca aaggaaattg
    22441 gttcgtaagt cgcttcttac cctttataat taacaatact ttcccatatt tttctgtgtt
    22501 tgtttcaaat tctaaatatc cccaagtctg tcctgctaat tgtaatttat actcaaacaa
    22561 atctgctgat gcaaatgcag tatcaatatg attaggtcgc gtccatgcat aaccattcga
    22621 cactatcatt gtctctcttt tttctagacg ttcatctaca taatcttttt gccctttcat
    22681 caaagtatct acaatttttt gtgcctcaag cgaatcaaag agatcctgat tcaacataat
    22741 tcttcctcct ccaaatactt tttaatgaat tatatcattt tcttaaagaa attactacaa
    22801 taattagctt tttcttaaag ttctgtgtca gagtaattta gaaaattata tcttctatag
    22861 taaaatcaat taaaaactga acaaatttat tgggaaattc aaatcacttt ctaaaaatat
    22921 tttaggaacc gtagtgtaat attccagatt caatttacta taaaactagc ctttctcctg
    22981 caaaagaaaa aggaaagact tcctttcgtg cctttcctct tacttgctac ttgtttaatt
    23041 atttttggta agctactgct tgtttgataa agtcctgaat cggctctcct tggtggagag
    23101 cttttactat tttcgaaccg acgataacac catctgacac cgcattgaag cgttccagat
    23161 cggcttgact agatacacca aaacctgtca agactgggat gtcggccact tgatgaagtt
    23221 gcgccaagtg cttgtccaaa tctgcacggt aattgcctga tttccctgtt accccattga
    23281 tggcaacggc atagacgaat ccctccgccc cttcaatcaa ctctttctgg cgctcaattc
    23341 ctgtggtcaa gcttactaaa ggaatcaagg cgatatctgt atctgccaaa aatggttcta
    23401 caaagttggc atgttcatga ggcaggtctg ggataatcaa gcccttcaca gctgtatcag
    23461 ccagatcttt gacaaagttc tccacaccgt actgaaagag ggggttgaag taggtcatga
    23521 tgaccagtgg aatctctgtt tcaatggttt tcaaggtttc aactaaagcc tgggtagagg
    23581 tcccgtgggc taaactgcgc aagccagctt cttcgataac aggtccatct gcaacagggt
    23641 ctgaaaaggg aatacccact tcaattgcag agacacccaa atcttctaaa aagtgaattg
    23701 tttcagcaag accatccaaa cctttttcgt ggtcaccagc catgatatag ggaacaaaaa
    23761 ttccttttcc agctgcttta atagcattta atttttttgt tagtgtctta ggcatgagct
    23821 tctcccttct ttgctgcatc tgcttccaag cggtctttta cttgaaccac atccttgtcc
    23881 ccacgacctg ataggcatac aatcatagac ttttctggtc caagttcttt ggccaatttc
    23941 accgcaaagg cgatagcatg gctagattcc aaagctggga taatcccttc cacacgagac
    24001 aagagttgga atccttccaa ggcttcttcg tctgtcacag ggacatagct ggcacgttta
    24061 atatcgtggt agtgagaatg ctctggaccg ataccaggat agtccaaacc tgctgagata
    24121 gagaaggctt caagaatttg accatgggca tcttggagca catccatgag ggaaccgtga
    24181 aggacacctg gacgaccctt ggtcaaggta gctgcgtggt gctccgtatc cacaccaaat
    24241 ccagccgctt cagctccata catggctact gactcatctt ctacaaaggg atggaagaga
    24301 ccgatggcat tcgacccacc accaacacag gctactaggg catctggcag attttgtcct
    24361 gtcaagtcac ggtactgttg tttagcctct cgaccaatga cactttggaa gtcacgaaca
    24421 atttctggaa atggatgagg ccccaaggca gaaccaagga tatagtgggt atcatctata
    24481 ttagccaccc atgaacgaag ggctgcattg accgcatcct tgagcacgcg cgaaccatct
    24541 gtcacggcct cgaccttagc tcccaaaagc tccatacgga agacattgag ggcttggcgt
    24601 ttgacatctt cctcacccat gtagatggta cattccatgt taaagagggc cgcagcagtt
    24661 gcagttgcca caccgtgctg accagcacca gtttctgcga taattttctt tttacccatg
    24721 cgtttggcaa gccaaacttg tcccaaggca ttgttaatct tgtgggctcc tgtatggtta
    24781 aggtcttccc gtttgagata aatcttggct ccgccgatat gctgggtcaa gttttttgcg
    24841 taataaagag gagtttcacg tcctacgtac tggcgcaaaa gctggtttaa ttcctcttgg
    24901 aaacttgggt ctgcctgact ttcacggtag gccttctcca actccaaaac tgctgtcatc
    24961 aatgtttctg ggacaaaacg tccgccgaat tttccgtaaa atccatcttt atttggttcc
    25021 tgatatgcca tgctttaccc tctctataaa tcttctaatc ttttcatgat ctttttgtcc
    25081 atctgtctcc actccgctcg atacatctac tgcataggga gtaaaatgtt gaattgcttt
    25141 tactacatta tcttcattaa ggccacctgc gataaagaag ggctgtgcta gtccagtcgt
    25201 atccagttga ccccaatcaa aggactgacc acttcctgcc acaggggcat caaagagtag
    25261 ataatctgcc tgagaattgg ggacatgccc atttccatct acctgcacag cctgaatact
    25321 ggcacaaggc aaattctcaa ataaatcagc tgccacctga ccgtgaactt gaaccaagtc
    25381 caagccaact ttgtcaatcg cttccagcag ttctacccga cttggtgaaa caaatactcc
    25441 aacctttttc acatctgcag gaataagctt tgccaactca gctgcctctt ctaaagtcac
    25501 ctgtctttta ctaggtgcaa agacaaaacc gatatagtcg gctcctgctg aaacggctgt
    25561 ttccaccgct tctttggtcg atagtccaca aattttaacc tttgtcaatc tgcaactcct
    25621 tgattctctg ggccacattt tctgcctgca taagagctgt ccctaccaaa attccgttaa
    25681 agtatggggc tagtcgttcc gcatcctgcc ctgtgaaaat ggcagattca gaaatgtaat
    25741 agcgaccttc ctcaaagtaa ggggctaaat ctacactggt ctgcaagtcg acctcaaagg
    25801 tagtcaagtt gcggttgttg accccgataa tctcagcacc aagtctgtgg gctacctcta
    25861 gttcagctag attgtgagtc tccactaaga cttccagacc aagctctgtc gcgtagtcat
    25921 acagttcctt gaggcgttct tcggacaagg ctgccacaat aagcaagata actgtcgcac
    25981 ctgtattgcg agcgcggatg atttgctttt catctatgat aaagtctttg ttgagcgtcg
    26041 gaatctctac ctgactggaa atttcccgta gataatccaa atgcccttta aagaaaacct
    26101 catctgtcaa caccgaaatc atcactgctc cgttttcttc ataagtctgg gcctgttgca
    26161 caatatccac atcgagattg atatctccca aactagggct agctttcttg acctcagcga
    26221 ttacctgcaa gcagtcctga tgattcttca aaaattctgc caagcgatag gtctggcgca
    26281 gaggctggat ttgctccagc ttcatctgct ccacctcacg cgccttctgc tctaagattc
    26341 gtgctaaaaa ttcctgactc atttttggta ctcctgtaac agtctgagtt tttcaagggc
    26401 cttgcctcta gcaatcactt gacgggccaa ggcaactcct tccttgatgc tatcaatctt
    26461 accattagca tagaaaccaa gaccagcatt caagactgtc gtttccaaga atggacttgc
    26521 ttcgtttttc agaacgctaa gcaaaatttc tgcattttcc tgagcattcc caccacgaat
    26581 atcttccata gcatagtctt ccattcccaa atcctctgga gtaaagcttg acaagctgat
    26641 ttcgccattt tcaagaagtg caatcttggt tgttccgttc aagccagctt catccaaccc
    26701 ttctggtcca gcaaccacga tggcacgttt gcgacccata tttttcaaaa cctgagctgt
    26761 actttctagg agttctggac gactaattcc aagaagctgt gtttctaaag ccattggatg
    26821 aatcagtgga ccagtcaagt tcataatcgt tggaattccc aattccaaac gagctggcat
    26881 gatgtatttc atagctgggt gcatattttt agcgaagaga aagacgattc cagttttatc
    26941 aaagacctta cctagttcag ctggtttgag gtcaagattg attcccaagg cttcgaggac
    27001 atctgcggaa ccagatttag aagaaatcga gcggttacca tgcttggcca tgtgaatacc
    27061 gccaccagcc aagacaaagg ctgcagttgt ggaaatatta aaactgaaag acttgtcccc
    27121 acctgtacca cagttgtcca tagcatcatg aatctcagtt ggaatatgct gggcatgtcc
    27181 tctcatgact tgggcaatgg ctgtacgttc ttcaggtgtt tcccccttca tcttaagagc
    27241 taagaggaga gaagcaatct gcgcttcagt tacacgccca gttacgatac gctcaatgac
    27301 atccgtcatt tccacacctg ataaattttc aaattttgct agtttttcaa taatctcttt
    27361 catcctagtt tcctcacttt acaaccttct cgataaaatt ccgaatagaa gacaagccgt
    27421 ctggcgttcc aatgctctct ggatggtact ggaagccata aatcggtagg tttttatgtt
    27481 gaatccccat gatggcttgg tcatcagtcg aacgagctgt cacttcaaag tcttctggca
    27541 tttcctcaat caaaatactg tgataacgca tgaccgcacg tccatcctca ataccttgat
    27601 acaaaacaga tggcgcttca aagttgatat tgctctgttt cccatgcatg acttttggag
    27661 ccaaacctag cttaccacca aagacttctg caatggcttg gtgacccaaa caaatcccta
    27721 gaatcggctt cttgcctgca aaatcacaaa tcatgtcttc catctttcca gcatcaactg
    27781 gccaaccagg accaggagaa aagaccagac catctgcttt ttcagcttct tcatacagct
    27841 tggaatcatc atttctcaaa acctgaactt ctgcaaaatt cccaatgtat tgggccaagt
    27901 tataggtaaa agaatcatag ttgtcaatca ataaaatcat ggtcttagtt ctccaattct
    27961 agtcatagat tttgctttgt taatggtttc ttggtattcg ttttgggcga tagagtcgta
    28021 gacaatccct gccccagcct gcacataggc tctttgattt ttgagaatca tggttcggat
    28081 ggcaatggcc aaatccatat cacccgtcgc agacaagtag ccgattgctc ctgcatatac
    28141 gctccgtttt tccgtttcca gttcatagat gcgtctcata gctcgaattt ttggtgctcc
    28201 agaaacggtt ccagcaggaa gcgttgcttt caaggcatcc atggcagtga gttctgcaag
    28261 caaacgtccc ttgaccacac tggtcaaatg catgacgtag cggaagagct ccacctccat
    28321 atacttagta acttggacac tggccgtttc agagatgcgg ccaatatcgt tacgccccaa
    28381 gtctaccaac attcgatgtt ctgctgtttc cttctcatca gagaggaggt cagtcgccaa
    28441 ggccttgtct tcttcatccg tagcccctct tggtcgcgtc cctgcaatcg gattggttgt
    28501 cacgatgcca tttttgacag aaaccaaact ttctggacta gctccgatga tttgataatc
    28561 cccaaaatca tagaaataaa ggtaattaga tggattagtc acgcggagat ttctgtagaa
    28621 gtcaaatgga tttccagtaa cttctgctga gaaacgctgg ctgagtacac attggaacat
    28681 atctccgtta cgaatcaagt cacgagctgt ttctaccatt ccctcaaact tatgtggagc
    28741 gatatgcggt ttgaagtcaa gtggtgataa atccaagtct tcaaattcat ttggagcagg
    28801 aatgcgtaat tcctcaagca cttggttcaa ggatttttcc aaggcctctt gactgcgctc
    28861 actataaagt gcatcctcta tgacatgtat cttctccttc ttgtggtcaa agaccatata
    28921 gctctcatag acaaagaaat gcatgtctgg cgtcccaatt gtatcctcag ggatttgacc
    28981 aatttcttca taaagcgaaa tcatatcgta accaacaaaa ccaatggctc ccccaccaaa
    29041 agggaggtct gaatggtgct ggctcttatg agtcacttca taaaggaaat ccaagggatc
    29101 ccgatcaatc gcttgaccat tttgatagag aactccattt tcaaacttaa tctcaaaaac
    29161 tggattatag gctaggatag aaaaacgagc tgtttccttg tctctcggaa tactctctaa
    29221 aataacctta tgttgcccct ttaagcgcat ataagccaag attggtgata agacatctcc
    29281 atgaatgatt cgttccattg tcatttccct ttcagttcta attctagttc gtggcgactg
    29341 tatgaaaaat ccccacgcaa aataacttgc gtgaggacga aattcgcggt gccacctcaa
    29401 ttataggatt tctcctatct ctcattcctg tctcagatat ctcctgtaac aggctgtgcg
    29461 ataaagggca ctcccttgag aatgatgttt tcttctctcg tttcagatga acccaacttt
    29521 acagctttct ctgcttgttt tcagcaacca caagctctct gtgagagaaa agactgtaat
    29581 ttttccatct attatttttt agcttctagt aatctgcaat cgcagctagg tccttgcctc
    29641 cacgaccaga gacattgatg aagagatgtt catctcggta cacctttata ctcttcgaaa
    29701 atctcttcaa accgcgtcaa cgtcgccttg ccgtaggtat ggttactgac ttcgtcagtt
    29761 ctatctgcaa cctcaaaaca gtgttttgag ctgacttcgt cagttctatc cacaacctca
    29821 aaacagtgtt ttgagcaacc tgcggctagt ttcctagttt gctctttgat tttcattgag
    29881 tattactagc ttttttcgta ttagtccagc ctttttgttt acttttagta ggaggcaagg
    29941 agctgtagat agaactcaag ttcatcaaag cgacttaagg ccctaataaa agataaacca
    30001 aacgacggat agaaaaaagc ccacacacag aatatacttc cgtgtgaggg cgttggtaac
    30061 gcggtgccac ctcaattata aagggactat ccctttacat ctctgccttg tttaacaaca
    30121 agctgcactg taaggtgtgc gcaccgaatt ttcattgttt caaattcatt ttcaaaatca
    30181 gcccactttc actacttcca accacctatt cacaatcacc acaggctccc tgaagatcaa
    30241 aaatagttac ttttctgatt tgttgaactt attttaatac tttgtttttt ctttgtcaag
    30301 acttttttac gatttttttg atatcattcg aatgtgacca tatcttcctt agatcgaaca
    30361 tgaacatgtc ccacttgtta gaaattggat ccaactcaat agaaactgaa tggaggctaa
    30421 acagaactta ttttagaaca ctccatcttt tccactagga ttttcaagaa ttaaacaata
    30481 ctagaaactc tgtctcctaa caaatttagg agaaacttca acagatgtga cactttcccc
    30541 tttaataatt gctaaaacac cttctatcat ttctttagcc aatttaacat aattgggagc
    30601 aattgtagac aaagctggag tataatactg agaaatagga atattatcaa atccaatgat
    30661 agaaatatca tctggaataa gaattccttt ctcatagcac gcacgaatca agccctgaac
    30721 cttttcatct cctgaaacaa aaataatgtc cggataattt tgggtagtca agtgctgcat
    30781 tgcataagaa taaactgaat caattgtaga taagccataa atgactttta aatccataaa
    30841 gtaattttta tcattcagaa aagaacgcac acctctttca cgatccttat taacatggga
    30901 ttctcctccc ataagcaacc acatattttt aaatttttct tcagttacag ctttcatcat
    30961 atcataagta gcttgaaaat tattattaga tacatagact actccagacg tttgagattc
    31021 accgaaaaca agaaaaggca tatggttctt ctttaaatac tgaattctga tatcatctac
    31081 actttcataa aaaacaataa caccatctac taggctacct gtgcttgata taattgaatt
    31141 actaattgta tcctcctctc caaagtactc aactatagca ttaacaccaa attctttaca
    31201 cgtccgtaac actttatcta acagcgtatg aaaccaaatt aaaggaaaag agtcgatttt
    31261 ttttacagaa atcaatatat ttatagcttc ttttttagtt aaattttttg catacgcatt
    31321 tggaatatac gacaattcct ctataacttt ttgaatcgct tgataagttt cttctttaac
    31381 atttactcca ccattaataa ctcgtgaaac tgtttttgga gaaaaacctg ataaacgtgc
    31441 aatatcataa atagttacct ttttcccatt tatatttttc atttcagtcc tccattacga
    31501 acattctaat attactatac aatatttaat tttttttaac aagagaattt agtaaattat
    31561 ttaagatcca caaattcaca aaattaattt tacaaatatt cttccccttc aaaaaaattt
    31621 aaattgcatt tcacaccttt atttttaaga atgtttccaa cttcacgaca aataaattca
    31681 tatgagaaaa aactgccata aaattgtaga ttaacttttt cagtaaaatg tgtaggattt
    31741 ataaaaacat ataatagcct gtcaatgtaa cattttaaca tagagttaat tttttcttta
    31801 aagataacat ttgttatcaa ctcatcagga ggtaaatgaa aggcaaacac catttcacaa
    31861 atatcataaa aagaaataaa tttgtatact tgtatcaaac aattattatc aaaatattct
    31921 attttaccta aatcaaaatt gattttataa tctttcataa aaacctctga gcaaaaatct
    31981 actcaaaaat tagatgatta aaacatctaa aaaacaaaag gacaaaaaca tctgtccctt
    32041 tgtttactaa atttcagcta atttcttcga cataaataac acctacaata ttagcaattt
    32101 cttccatcag tcgaagatgt tcaaatctac ctgataattc cagagtaata aatgacgcta
    32161 tttttttatc tggaacatca aagtattcaa ttctgtcaga attaacatct ccaaacgctg
    32221 ttcttgaatc ggtcattctg ataccatttt ctgcacaata aaccaataca cgattatagg
    32281 cttctgtaga tttaaccact atatacaatt caatcatttt agaacgattt tgtagatatt
    32341 tttttagtgg ttggaacatg gatatcacac cccaaacaga aatggctact aaaagagctc
    32401 cctcataaaa acctactcca atagctaatc caattcctgc cgaagcccaa atgcctgctg
    32461 cagttgtcag acctgtaatt ttctttttat ctgtaataag aatcgttcca gcgcctagaa
    32521 aacccacacc tgatataact tgagctccta atcgtgtagg atctcctgtc ccaaatttat
    32581 aagatacgta ttcattcgtc atcataatca aacatgcagc tagacaaaca atactataag
    32641 ttcggatgcc tgcaggctgg gatttgctcc ctctctctaa accaattata ctaccaatga
    32701 ctactgataa aacaatcctg acaactattt caatatttga taacccaaga ctagtggctg
    32761 tcatgattat ttccttactt tacgccccgg tctttgtgtg aagtataata ccgttccaga
    32821 aataatcatc agaacaattg tataaacaaa taccagagct tgtgcattag atgttgctgt
    32881 ttcatcacct gcagatcgaa tcgtaatacc taatggttga gctaggggat ggtaaaggaa
    32941 tacagataag tcgaagtcag ttaataaaga gttaaagttt aaagcaataa cagagagaac
    33001 aaccggtaaa ataaatggaa tgataacctt catcatagta taaaaaggtg aagcacccat
    33061 acttcttgct gcatcttcca tctcatcatc aacactaaat aaaatagcac gtaccattct
    33121 ataagaaaat gggattttta caactatata tgcaataagt agaattacca aactacctac
    33181 caaaatctga ttcaagacaa gaaattgtgg ctgattaaaa gtaaataata aacttactgc
    33241 taaaagcgta cttggtaata accaaggaag tagagcacca tattcaaata agaaatcaaa
    33301 acgagattta tgttttctga caacacgagc aaatacaact gcgagaattg ttgctgttgt
    33361 cgcagcaata atagaataaa taaagctgac caagaatgga gagaatgccg cactattact
    33421 aaagaataag cgataatttt ctaaagtaaa gtttgataat gttaagttac ctgtttgaat
    33481 tgcaactgga tctgtaaatg agtataatac tataaaaatt agtggaagca tgaaaactgt
    33541 gaacaatcca tatgctacaa tgtgagcaat gatattccaa ggcttagacg caattttttg
    33601 ttttttaaga ggcgctttag tcttagagat agaaatataa tttccacctt tttctatctt
    33661 attcatgata gtaagcaaaa ttgtagttgc aatacctaaa ataattgcaa gtaaggcagc
    33721 taaatcacga gaattcccca tccctgcaaa tgtaataatc attggattta tagtttgaaa
    33781 ttctttacca ccaacaatca tgggtgctgc tactgcagat aaaccactaa gaaaaaccat
    33841 aatagtaagt gcaaatagag ttggaattaa ggttggtaac actacttttc ggaaaacagt
    33901 aaatggtttt gctcccatat ttcgagcagc ctcaatagtg tgatagtcaa cgcttcgaat
    33961 tgtatttgtt aaaaacaatg tatgattagc agttcctgaa aatgtcataa tgaataagac
    34021 tgcaccatac ccaataaacc agttagggtc taaagaaggg ataacatttt gtaaaaattt
    34081 tgtaatcaat ccatatggac catagacaaa tttatatcca gtcgctaaaa ccactcctcc
    34141 ataaattaaa gaggtcatat aacctaattt taaaatttta gcacctttaa tatcaaagta
    34201 ctctgtaaat agaacacaaa gaatacctac gacattaact gtaataatga gtgaaaatgc
    34261 taacttaaaa ctgttcataa tactctgaag tgccctctga gattttagaa cacgatgtac
    34321 agcatcaagg gaaaattctc ctccttttac aaatacattc actactagat caaagtttgg
    34381 ataaataata aatgttacta agaaccagat taaccctaaa cgaataagcc aatcttttaa
    34441 atttaattta tgacgcatac tgcacctcct taaaattgca gaacgtctga tggtgtgata
    34501 aataattcca cactttctcc gacagatcta atagcagcct gactatcaat acttgttaca
    34561 ttaagaatct gactttcaga aacttttatt gtatagtgaa ttgtaactcc agaaaactca
    34621 acatcaataa ttgtcccttt tagaatgaaa tcttgttcag tttcacgatt gaatcgaact
    34681 ttctctaatc gaatgtatcc ttttttatct tctaagaaaa cgcttgtatt tttcagtaat
    34741 acttcgtgga ctgtttcatc ggtcaaaaca ttaatatctc caataaaatc acatacaaat
    34801 tcagtttgag aattatgata aatctctact ggtgtaccga cctgttcgat gtatccattg
    34861 ttaaagactg caattctatc agataaagtc aaggcttcct cttgatcatg agtaacatat
    34921 aaagtagtaa tacctaactc tttttgaagt cttttcaact cttttctcaa atctacacgt
    34981 aattttgcgt caaggtttga caatggttca tctagacaaa gaattttagg ttcaagaacc
    35041 agagcacgag ccaatgctac cctttgttgt tgacccccag ataattctga tacattacgc
    35101 tgtaactgtt gatcagagat cttaattttt gctgccactg ctgatacttt agctttaata
    35161 acatctggag ctaccttctt aacttttaaa ccaaatgcaa tattatcaaa aacagtcata
    35221 gttggaaata gcgcataaga ttgaaataca ataccaattc cacgcttttc aggttccaaa
    35281 tgagtgacat ctgttccatt aacttcaata cttcctgatg atggatctaa aaaacctacc
    35341 aatgctctca aagtagttga tttaccacat cctgaaggcc caagaaatgt aaagaattcc
    35401 ccttcatgta tatctaaatt cagattatca attgcaacaa aatcaccata tttaatttga
    35461 atattatcaa atttaatcat ctcactaact ccctctatta ctaaaccaaa agcctctctt
    35521 tatttcttcc ttaaatttag aaataataga gagacttgga cataaaaaat aactcttatt
    35581 tcttatttta cgtattctaa ttcagctttt tctacccatt catccaaatg ctttccaaca
    35641 gcttcccagt caatattttg tggtttcact tgatcaacaa attttttcgt atcttcaggt
    35701 aactctttta gggcatcttt atttgcagga atagatccaa attttttact atattctact
    35761 tgaatttctg attgaccaaa ccaatcaata aattctttag ctaacgcttg ttttttacta
    35821 gtgcttaaaa ccatagtttg ttcagttaca aatggtacac caatctcagg agtcataact
    35881 ttgaattcaa cattttgttc tttttgtccg attaacgctc cagaacccca gatcataccg
    35941 tattgaattg ggctttcttt atctaacgct ttaacaactg agctttcacc tttttgaaga
    36001 gtataggcat ttgcaaagta ttcttttgca acttcccatc ctttttctga tacgcctaaa
    36061 tctccttttt catcaaggta acgaactaag atacttgcta gaattgcccg tcctgtacca
    36121 ccttgaagac cataaattga atatttacct ttatacttac tacctaattc agtccaatct
    36181 ttaggcattt cttttacatc aggcgcccca attaaaacta atggttgaac aatcacagga
    36241 ttataataat tatctttatc tgataaagat tgatcaattt tatctaacca tttaggcttg
    36301 tactgtacta gtaatttttg atctctaatt ttatttgagt caacagcacc aattccaaat
    36361 accatatctg caactgcatt attcttctca gcaataacac ggtctgctaa ttgagcgcca
    36421 gcaatatcaa ccatttttat attaaaacca gcttcttttg ctttagcagt taaccaatca
    36481 ccacgaccat ttgagactga gttcgaatag attactaatt cttgactttt atcagctttt
    36541 tcttcagatg aagaagcagt cgtagaattt gaacctccag agcaagcagc aagtgtagta
    36601 agagcaactc ccgttgcaag tacagtagac caaactttca tttttttcat gataagttct
    36661 ccttttttat tattttattt aaatttttcg tgatatggaa caaattgtct catatcttca
    36721 aatacagtat agtcaatacg gtttacagta atagttggaa tcttctctaa taaaatttca
    36781 gttaattctg ctctgacttt agtaaactct tcttcctcct cttcggttag aggaatccga
    36841 agatacccaa ttgaaatatg gaattgatat ctatcatgat tagggaaaca aacacctgct
    36901 ttttctgaga cataagtacg aatttcttct aatctctttg cagaagcttc atctgcaggt
    36961 tcaactagta tgttttgttt tcccatttca gttatacgca tatgaatttc ttcatccaac
    37021 aatggaaaaa tttcaagttg tttagcaaag taatcatgta tttcctgtaa aggtgtatct
    37081 agaggaagat tactgctcca aaactccgtt tcacgatttt catggcacaa caattcaatt
    37141 acagtcatgt gaatagaatt ccttggagtt aaagtaaact tatcgataaa tggtaattct
    37201 ctataacgtg attgaataat atcaacaact tccatcaaat cttgtttagt ataaagattt
    37261 gctacaactg tattcccagg gaaatgatta aattccccat tctctttgaa cttaattttt
    37321 gttaagtttt tcatataaag accttctttt ttatatttga catcggtgtc attgtgttta
    37381 cattatacaa tgaaaccgtt tcctttgtca agcgctgtca aacatttttt ttaatttatc
    37441 tttcattaaa ag
//
LOCUS       DAVBBO010000017        34347 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ST1
            SAMEA2066453-rid20184263.denovo.017, whole genome shotgun sequence.
ACCESSION   DAVBBO010000017 DAVBBO010000000
VERSION     DAVBBO010000017.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2066453
            Sequence Read Archive: ERR351777
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 34347)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 34347)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980402.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980402.1
            Genome Coverage       :: 176x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:17:33
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,141
            CDSs (total)                      :: 2,104
            Genes (coding)                    :: 1,953
            CDSs (with protein)               :: 1,953
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 16S)
            partial rRNAs                     :: 1 (23S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 151
            CDSs (without protein)            :: 151
            Pseudo Genes (ambiguous residues) :: 0 of 151
            Pseudo Genes (frameshifted)       :: 73 of 151
            Pseudo Genes (incomplete)         :: 76 of 151
            Pseudo Genes (internal stop)      :: 40 of 151
            Pseudo Genes (multiple problems)  :: 32 of 151
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..34347
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2066453-rid20184263.denovo.017"
                     /strain="ST1"
                     /db_xref="taxon:1313"
     gene            <1..4786
                     /locus_tag="VQU30_000831"
     CDS             <1..4786
                     /locus_tag="VQU30_000831"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000682812.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HET2446967.1"
                     /translation="QGERGLTGAKGEKGDQGERGLTGAQGEKGDRGERGLTGAKGEKG
                     AQGQAGRDGVTPTVTVKDNKNDGTHTITINDGRGNVTSTVVRDGFDGASPLVATQRND
                     ADKTTTVIFYYDKNGNNELDASDKKLKEVVIADGAKGEKGDKGEQGLQGRDGEQGPKG
                     EDGKTPTVKVTDGQDGTHTITINDGKGGITTTVVRDGFDGASPLVSTHRNEADKTTTV
                     IFYYDLNDNNQFDEGDTKLKEVVIADGKQGPKGDKGDNGKDGFTPEVTVTDNNNGTHT
                     ITITQPDNRPSLTTIVKNGEDGKTPKVKAERDDAKKQTTLTFYIDKDGDGSYTAGKDE
                     LVQTTVVKDGQDGAAGASGRDGKEVLNGKVDPTTEGKDGDTFVNTQTGDVFVKKGNTW
                     EPAGNIKGPKGDKGADGAKGEKGAQGERGLTGAQGVKGEKGDQGERGLTGSKGEKGDQ
                     GERGLTGAQGAKGDKGEQGLQGRDGAQGPKGADGQRGPAGPQGPKGEQGNPGTPGKDG
                     KSLIAVKNGTETKVYVEDPARPGQPLNPNQPLATITDGRNGTNGQSPTITATRSVQNG
                     KNGVLVTITPVGGRPQTTFVEDGQKGADGKTPTVTITEGQNGTHTLTVHNPGSPDVTT
                     TIRDGATGQAGRDGKDVLNGKVNPQPNQGKNGDKYINTETGDVYVKNNGNWDKEGNIK
                     GPKGDKGADGAKGEKGDQGERGLTGAQGAKGADGAVGRDGRDGKDVLNGKANPEAHQG
                     KDGDKYVNTETGDVFVKNNGNWDKEGNIKGPKGDKGERGEDGKTPEVTVTPGKDGHST
                     DITFTVPGKDPVTVNVKDGENGLNGKTPKVDLLRVQGKNGNPSHTIVTFYTDENNDGK
                     YTPGTDELLGSEMIKDGAKGADGRDGKSLLTVKDGKETKVYQEDPANPGQPLNPEKPL
                     AVIRDGVDGKSPTVTAVRKDEAGHKGVEITVDNHDGSQPTTVFVQDGAKGETGATGQD
                     GQTPTITTQRGQDGQSTVVTITTSGKDPVTFTVKDGKNGKDGRAPKIKVEDITSPSRI
                     RRDTDAAATPTRNGIRVTVYDDVNDNGVYDEGVDKVLNSKDIYNGIDGRDGSAPTITT
                     KDNGDGTHTITVQNPDGSESTTVVKDGKDGKTANITTTENPDGSHTITVTNPDGSTKE
                     TVVKNGKDGKTPKVEVTDNNDGTHTVKVTDGDGNVTNAIIKDGKDGKAATATTTENPD
                     GSHTVTITNPDGTKNEFVVKNGRDGVDGRTPTASVRDNGDGSHTIVITNPEGVTTETT
                     VRDGKSPKVTITDEQNGTHKISVLNGDGTTTTTTVRDGREPKLEVIDNNDGSHTIKVT
                     GADGKGTTTTIFDGKSPKANIVDNGDGTHTLTIVDSDGREYKSIIKDGKDGKDSVSPT
                     VTVKNNNDGTHVVTITNPDGSKTEMVIKDGKDGKSPKVSVEDNGDGSHTITIINSDGT
                     VTKTVIKDGRDGRDGRDGKDGKDGKDGKCGCQDKPVTPSNDKPVPPTPNVPTPEVPVK
                     PVPAQPTPNVPTPEVPVQPTPAVPTPEVPVKPVPAVPEQPVVPTPAQPATPVNANPVA
                     PTTGKENRGDKLPETGSQSDYISVLLGSGILLSLYVGRRKEA"
     gene            complement(5023..5571)
                     /locus_tag="VQU30_000832"
     CDS             complement(5023..5571)
                     /locus_tag="VQU30_000832"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000039625.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent oxidoreductase"
                     /protein_id="HET2446968.1"
                     /translation="MSKKVLFIVGSLRQGSFNHQMALEAEKALAGKAEVSYLDYSALP
                     LFSQDLEVPTHPAVAAAREAVLVADAIWIFSPVYNFSIPGTVKNLLDWLSRALDLSDT
                     RGVSALQDKFVTVSSVANAGHDQLFAIYKDLLPFIRTQGVGDFTAARVNDSAWADGKL
                     VLEETVLNSLEKQAQDLVEAIQ"
     gene            5892..6380
                     /locus_tag="VQU30_000833"
     CDS             5892..6380
                     /locus_tag="VQU30_000833"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000747178.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5590 domain-containing protein"
                     /protein_id="HET2446969.1"
                     /translation="MKKRQNKAKNNLLWQYGLGMTILFVVISASFLYMVSLSMKPYQT
                     AKSEGEKLAQQYAGLEQADQVDLYNGLESYYSVLGRNKQQEALAVLIGKDDHKIYVYQ
                     LNQGVSQEKAETVSKEKGAGEIDKIIFGRYQDKPIWEVKSGSDFYLVDFETGALVNKE
                     GL"
     gene            6377..7564
                     /locus_tag="VQU30_000834"
     CDS             6377..7564
                     /locus_tag="VQU30_000834"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000777780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HET2446970.1"
                     /translation="MKLSNRVLEMEESVTLAAGARAKALKAEGRDILSLTLGEPDFTT
                     PKNIQDAAIASIRDGRASFYTVTSGLPELKAAVNSYFERFYGYSVASNQVTVAAGAKY
                     SLYTFFMAVVNPGDEVIIPTPYWVSYGDQVKMAEGVPVFVSAKEDNHFKVTVEQLEAA
                     RTDKTKVLVLNSPSNPTGMIYTREELLAIGNWAVENDILILADDIYGRLVYNGHEFTP
                     ISSLSEAIRKQTVVINGVSKTYAMTGWRIGYAVGEADIIAAMSKIAGQTTSNPSAVAQ
                     YAAVEALSGEQDTVESMRQAFEERLNTIYPLLAEVPGFEVVKPQGAFYLFPNVKKAME
                     MKGYTDVTDFTTVILEEAEVALVTGAGFGAPENVRLSYATDLDTLKEAVERLKAFMGS
                     END"
     gene            7557..7922
                     /locus_tag="VQU30_000835"
     CDS             7557..7922
                     /locus_tag="VQU30_000835"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HET2446971.1"
                     /translation="MIDHFEIKVKDLQISEGFYRSFLAPLDYKLAFKTSSLISFLSPN
                     SPHPGGDFWLTQGTQDPVHFAFLAENKEEVQACYEAGLEAGGRDNGAPGYRSEHPIYY
                     AAFMIDLDGNNIEVVCHKE"
     gene            7938..9284
                     /gene="asnS"
                     /locus_tag="VQU30_000836"
     CDS             7938..9284
                     /gene="asnS"
                     /locus_tag="VQU30_000836"
                     /EC_number="6.1.1.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000038477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="asparagine--tRNA ligase"
                     /protein_id="HET2446972.1"
                     /translation="MMTKRVTIIDVKDYVGQEVTIGAWVANKSGKGKIAFLQLRDGTA
                     FFQGVAFKPNFVEKFGEEVGLEKFDVIKRLSQETSVYVTGIVKEDERSKFGYELDITD
                     IEVIGESQDYPITPKEHGTDFLMDNRHLWLRSRKQVAVLQIRNAIIYATYEFFDKNGF
                     MKFDSPILSGNAAEDSTELFETDYFGTPAYLSQSGQLYLEAGAMALGRVFDFGPVFRA
                     EKSKTRRHLTEFWMMDAEYSYLTHDESLDLQEAYVKALLQGVLDRAPQALETLERDTE
                     LLKRYIAEPFKRITYDQAIDLLQEHENDEDADYEHLEHGDDFGSPHETWISNHFGVPT
                     FVMNYPAAIKAFYMKPVPGNPERVLCADLLAPEGYGEIIGGSMREEDYDALVAKMDEL
                     GMDRTEYEFYLDLRKYGTVPHGGFGIGIERMVTFAAGTKHIREAIPFPRMLHRIKP"
     gene            9437..9727
                     /locus_tag="VQU30_000837"
     CDS             9437..9727
                     /locus_tag="VQU30_000837"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018030687.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S6"
                     /protein_id="HET2446973.1"
                     /translation="MAKYEILYIIRPNIEEEAKNALVARFDSILTDNGATVVESKTWE
                     KRRLAYEIQDFREGLYHIVNVEANDDAALKEFDRLSKINADILRHMIVKIDA"
     gene            9739..10209
                     /gene="ssbA"
                     /locus_tag="VQU30_000838"
     CDS             9739..10209
                     /gene="ssbA"
                     /locus_tag="VQU30_000838"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003083754.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein SsbA"
                     /protein_id="HET2446974.1"
                     /translation="MINNVVLVGRMTRDAELRYTPSNVAVATFTLAVNRTFKSQNGER
                     EADFINVVMWRQQAENLANWAKKGSLIGVTGRIQTRSYDNQQGQRVYVTEVVAENFQM
                     LESRSVREGHTGGAYSAPTANYSAPTNSVPDFSRNENPFGATNPLDISDDDLPF"
     gene            10241..10480
                     /locus_tag="VQU30_000839"
     CDS             10241..10480
                     /locus_tag="VQU30_000839"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983142.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S18"
                     /protein_id="HET2446975.1"
                     /translation="MAQQRRGGFKRRKKVDYIAANKIEYVDYKDTELLSRFVSERGKI
                     LPRRVTGTSAKNQRKVTTAIKRARVMALMPFVNED"
     gene            10775..12175
                     /locus_tag="VQU30_000840"
     CDS             10775..12175
                     /locus_tag="VQU30_000840"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006145273.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional Cof-type HAD-IIB family
                     hydrolase/peptidylprolyl isomerase"
                     /protein_id="HET2446976.1"
                     /translation="MDAKLRYKAKKIKIVFFDIDDTLRNSKTGFIPTTIPTVFKQLRE
                     KGILTGIASGRGIFGVVPEIRDLKPDFFVTLNGAYIEDKKGQVIYQHQIEKSYVEEYI
                     SWAKQEGIEYGLVGSHDAKLSTRTDMMSEAINPIYPDLDVDPDFHEKEDIYQMWTFED
                     KGDDLHLPDSLSDKLRMVRWHQHSSDIVPISGSKATGVEKVVEHLGLKPEKVMVFGDG
                     LNDLELFDYAGISVAMGISHDKIKEKADYITKTLEEDGIFDALEVFGMVEKELHFPQV
                     DIETVEGPLATIKTNHGDLRIKLFPEHAPKTVANFVSLSKDGYYDGVIFHRIIKDFMI
                     QGGDPTGTGMGGESIYGESFEDEFSEELYNIRGALSMANAGPNTNGSQFFIVQNQHLP
                     YSKKEITRGGWPEPIAEIYANQGGTPHLDRRHTVFGQLADEASYAVLDVIAAVETGAM
                     DKPVEDVVIETIEIED"
     gene            12177..12536
                     /locus_tag="VQU30_000841"
     CDS             12177..12536
                     /locus_tag="VQU30_000841"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000689596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S1 RNA-binding domain-containing protein"
                     /protein_id="HET2446977.1"
                     /translation="MKIGDKLKGRITGIQPYGAFVELETGDTGLIHISEIRTGFIENI
                     HETLKVDEEVQVQVVDLDEFTGKASLSIRTLEEEKYQFPRRRRFSSDRFNYGFAPFRR
                     MLPIWTGEALHHLKKKK"
     gene            12590..13339
                     /locus_tag="VQU30_000842"
     CDS             12590..13339
                     /locus_tag="VQU30_000842"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000390787.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA1(Val) (adenine(37)-N6)-methyltransferase"
                     /protein_id="HET2446978.1"
                     /translation="MEEEQLLKSGERINQLFSTDIKIIQNREVFSYSVDSVLLSRFPR
                     FPKKGLIVDFCAGNGAVGLFASTRTQAQILSVEIQERLADMAERSVRLNGLEEQMQVI
                     CDDLKNMPAHIQGSKVDMILCNPPYFKVDPYSNLNESEHYLLARHEITTNLEEICHSA
                     QSILKSNGRLAMVHRPDRLLDILDTLKRHNLAPKRLQFVYPKREKEANMLLIEAIKDG
                     STSGFKVLPPLIVHNDDGSYTPEIEEIYYGS"
     gene            13329..13628
                     /locus_tag="VQU30_000843"
     CDS             13329..13628
                     /locus_tag="VQU30_000843"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GIY-YIG nuclease family protein"
                     /protein_id="HET2446979.1"
                     /translation="MDHKAYMYVLECRDGSYYIGYTTDMRRRLAIHNSGKGAKYTRAR
                     LPVKLIYAQGFASKEEAMSAEALFKRKKRPQKEEFLSENQDRNLLSYFEESWGVL"
     gene            13699..14634
                     /locus_tag="VQU30_000844"
     CDS             13699..14634
                     /locus_tag="VQU30_000844"
                     /EC_number="3.6.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000036024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="manganese-dependent inorganic pyrophosphatase"
                     /protein_id="HET2446980.1"
                     /translation="MSKILVFGHQNPDSDAIGSSVAFAYLAKEAYGLDTEAVALGTPN
                     EETAFVLNYFGVEAPRVITSAKAEGAEQVILTDHNEFQQSVSDIAEVEVYGVVDHHRV
                     ANFETASPLYMRLEPVGSASSIVYRMFKEHGVAVPKEIAGLMLSGLISDTLLLKSPTT
                     HPTDKIIAPELAELAGVNLEEYGLAMLKAGTNLASKSAEELIDIDAKTFELNGNNVRV
                     AQVNTVDIAEVLERQAEIEAAMQAANESNGYSDFVLMITDIVNSNSEILALGANMDKV
                     EAAFNFKLENNHAFLAGAVSRKKQVVPQLTESFNA"
     gene            14721..15233
                     /locus_tag="VQU30_000845"
     CDS             14721..15233
                     /locus_tag="VQU30_000845"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000892254.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoylalanyl-D-glutamate--2,
                     6-diaminopimelate ligase"
                     /protein_id="HET2446981.1"
                     /translation="MLENGDLIFVRDGSDMGQAIQTSTGNYSHVAIYLDGMIYHASGQ
                     AGAVCQEPADFFESNHLYDLYVYPEMDIQSVKERACRHLGAPYNASFYPDAAGFYCSQ
                     YIAEILPIFETIPMKFGDGEQEISDFWREYYIELGLPVPLNQAGTNPSQLAASPLLQC
                     KERNLHDSDF"
     gene            15270..15865
                     /locus_tag="VQU30_000846"
                     /pseudo
     CDS             15270..15865
                     /locus_tag="VQU30_000846"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809149.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1803 domain-containing protein"
     gene            15966..16160
                     /locus_tag="VQU30_000847"
     CDS             15966..16160
                     /locus_tag="VQU30_000847"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000051203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CsbD family protein"
                     /protein_id="HET2446982.1"
                     /translation="MSLENKLEQATGAVKEGFGKVTGDSKTELEGAVEKTVAKAKDVV
                     EDAKGAVEGAVEGLKNVFTK"
     gene            complement(16206..17651)
                     /locus_tag="VQU30_000848"
     CDS             complement(16206..17651)
                     /locus_tag="VQU30_000848"
                     /EC_number="6.3.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--L-
                     lysine ligase"
                     /protein_id="HET2446983.1"
                     /translation="MIKIETVLDILKKDGLFREIIDQGHYHYNYSKVIFDSISYDSRK
                     VTEDTLFFAKGAAFKKEYLLSAITQGLAWYVAEKDYEVDIPVIIVNDIKKAMSLIAME
                     FYGNPQEKLKLLAFTGTKGKTTATYFAYNILSQGHRPAMLSTMNTTLDGETFFKSALT
                     TPESIDLFDMMNQAVQNDRTHLIMEVSSQAYLVHRVYGLTFDVGVFLNITPDHIGPIE
                     HPSFEDYFYHKRLLMENSRAVIINSDMDHFSVLKEQVEDQDHDFYGSQFDNQIENSKA
                     FSFSATGKLAGDYDIQLIGNFNQENAVAAGLACLRLGASLEDIKKGIAATRVPGRMEV
                     LTQKNGAKVFIDYAHNGDSLKKLINVVETHQTGKIALVLGSTGNKGESRRKDFGLLLN
                     QHPEIQVFLTADDPNYEDPMAIADEISSYINHPVEKIADRQEAIKAAMAITNHELDAV
                     IIAGKGADCYQIIQGKKESYPGDTAVAENYL"
     gene            17757..19379
                     /locus_tag="VQU30_000849"
     CDS             17757..19379
                     /locus_tag="VQU30_000849"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398581.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide biosynthesis protein"
                     /protein_id="HET2446984.1"
                     /translation="MSHENNHQQAQMLRGTAWLTASNFISRLLGAVYIIPWYIWMGAY
                     AAKANGLFTMGYNIYAWFLLVSTAGIPVAVAKQVAKYNTMREEEHSFALIRSFLGFMT
                     GLGLVFALVLYVFAPWLADLSGVGKDLIPIMQSLAWGVLIFPSMSVIRGFFQGMNNLK
                     PYAMSQIAEQVIRVIWMLLATFIIMKLGSGDYLAAVTQSTFAAFVGMVASFAVLIYFL
                     AQEGSLKRVFETGDKINSKRLLVDTIKEAIPFILTGSAIQLFQILDQLTFINSMSWFT
                     NYSNEDLVVMFSYFSANPNKITMILISVGVSIGSVGLPLLTENYVKGDLKAASRLVQD
                     SLTLLFMFLLPATVGVVMVGEPLYTVFYGKPDSLALGLFVFAVLQSIILGLYMVLSPM
                     LQAMFRNRKAVLYFIYGSIAKLVLQLPTIALFHSYGPLISTTIALIIPNVLMYRDICK
                     VTGVKRKVILKRTILISLLTLVMFLLIGTIQWLLGFFFQPSGRLWSFFYVALVGAMGG
                     GLYMVMSLRTYLLDKVIGKAQADRLRAKFKLS"
     gene            19583..21541
                     /locus_tag="VQU30_000850"
     CDS             19583..21541
                     /locus_tag="VQU30_000850"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000748873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide ABC transporter substrate-binding
                     protein"
                     /protein_id="HET2446985.1"
                     /translation="MKKSKSKYLTLAGLVLGTGVLLSACGNSSTASKTYNYVYSSDPS
                     SLNYLAENRAATSDIVANLVDGLLENDQYGNIIPSLAEDWTVSQDGLTYTYKLRKDAK
                     WFTSEGEEYAPVTAQDFVTGLQYAADKKSEALYLVQDSVAGLDDYITGKTSDFSTVGV
                     KALDDQTVQYTLVKPELYWNSKTLATILFPVNADFLKSKGDDFGKADPSSILYNGPFL
                     MKALVSKSAIEYKKNPNYWDAKNVFVDDVKLTYYDGSDQESLERNFTAGAYTTARLFP
                     NSSSYEGIKEKYKNNIIYSMQNSTSYFFNFNLDRKSYNYTSKTSDIEKKSTQEAVLNK
                     NFRQAINFAFDRTSYGAQSEGKEGATKILRNLVVPPNFVSIKGKDFGEVVASKMVNYG
                     KEWQGINFADGQDPYYNPEKAKAKFAEAKKELEAKGVQFPIHLDKTVEVTDKVGIQGV
                     SSIKQSIESVLGSDNVVIDIQQLTSDEFDSSGYFAQTAAQKDYDLYHGGWGPDYQDPS
                     TYLDIFNTNSGGFLQNLGLEPGEANDKAKAVGLDVYTQMLEEANKEQDPAKRYEKYAD
                     IQAWLIDSSLVLPSVSRGGTPSLRRTVPFATAYGLTGTKGVESYKYLKVQDKIVTTDE
                     YAKAREKWLKEKEESNKKAQEELAKHVK"
     gene            21713..22648
                     /locus_tag="VQU30_000851"
     CDS             21713..22648
                     /locus_tag="VQU30_000851"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000768996.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET2446986.1"
                     /translation="MKLKLLRVDTKVIMGSFLLVLSSLLALLLPLILKGLIDGSSIEN
                     IGSKVFQSFLIFIGQALFSSIGYYLFSQSGEKKIAKIRKKVIEGLIYAEKSFFDKSQS
                     GELTSAIVNDTSVIREFLITTFPNIILSLVMVLGSIVVLFSLDWNLSLLLFITLPCMM
                     FIILLLSNISEKYSRRLQEEIGFLTGQLTEKIQEHELIKTNQAEKSVQDVLDNCIERV
                     QNNSLKSDRVTSFETPFALLFIFATIAVMLTYGGYRVSAGYISVGTLVSFLIYLFQLL
                     NPISNIANFVTVYSRSKGSSVALENLLAVPKEKFE"
     gene            22673..23325
                     /locus_tag="VQU30_000852"
                     /pseudo
     CDS             22673..23325
                     /locus_tag="VQU30_000852"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864981.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
     gene            23483..24577
                     /locus_tag="VQU30_000853"
     CDS             23483..24577
                     /locus_tag="VQU30_000853"
                     /EC_number="2.5.1.48"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007521335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cystathionine gamma-synthase"
                     /protein_id="HET2446987.1"
                     /translation="MSKELHINTILAQAGIKSDEATGALVTPLHFSTTYQHPEFGRST
                     GFDYTRTKNPTRSKAEEVLAAIESADYALATSSGMSAIVLAFSVFPVGSKVLAVRDLY
                     GGSFRWFNQVEQEGRFHFTYANTEEELIAELEKDVDVLYIETPTNPLMLEFDIEKLAK
                     LAHAKGAKVVVDNTFYSPIYQRPIEDGADIVLHSATKYLAGHNDVLAGVVVTNSLELY
                     EKLFYNLNTTGAVLSPFDSYQLLRGLKTLSLRMERSTANAQEVVAFLKDSPAVKEVLY
                     TGRGGMISFKVADETRIPHILNSLKVFSFAESLGGVESLITYPTTQTHADIPAEVRHS
                     YGLTDDLLRLSIGIEDARDLIADLRQALEG"
     gene            24585..25751
                     /locus_tag="VQU30_000854"
     CDS             24585..25751
                     /locus_tag="VQU30_000854"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000521357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HET2446988.1"
                     /translation="MGKYDFTSLPNRLGHHTYKWKETETDSEVLPAWIADMDFVVLPE
                     IRQAVQTYADQLVYGYTYASEDLIKEIQKWEATQYGYNFDKEALVFIEGVVPAISTAI
                     QTFTKEGEAVLINTPVYPPFARSVKLNNRRLITNSLVEKDGLFEIDFDQLEKDLVEEE
                     VKLYILCNPHNPGGRVWEKEVLEKIGQLCQKHGVLLVSDEIHQDLTLFGHKHQSFNTI
                     NPAFKNFAIVLSSATKTFNIAGTKNSYAVIENPKLRLAFQKRLLANNQHEISGLGYLA
                     TEAAYRYGKDWLEELKQVFEDHINYVVDLFGKETKIKVMKPQGTYLIWLDFSAYDLTD
                     ETLQELLRNEAKVILNRGLDFGEEGSLHARINIAMPKSLLQEVCQRIVATFAKR"
     gene            25844..28942
                     /locus_tag="VQU30_000855"
     CDS             25844..28942
                     /locus_tag="VQU30_000855"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001096241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HET2446989.1"
                     /translation="MAKLIPGKIRIEGVALYETGKVDIIKEKNNRLYARVAEEELRYS
                     LEDDLVFCACDSFQKRGYCVHLAALEHFLKNDERGQEILWSLEEGHEEKEAVETKVTL
                     GGKFLNRILSPKSECAYELSAVGQVEAGTNHILWTLRIGQINSQKYYVIRDIPLFLRI
                     VEQRKSYMIGKIYEESLSWEAFDDASQELLTFLHGLTEEGLVPDLFFQNQGRHLFFPL
                     TFFEQGVNLLMALPHFQFDHQVDSYQTLLFQDMHADANLFAFTVTEYSDYFEMEISES
                     PRVNVFYQGAVLFHKGQVYFLTDQQMRLLKEIKALPVGQQGKKYLQFDSSDRDKLASC
                     LTLFIQMGTVSAPERLQIKTFAPSFYFDREEDNRIRLEIQFDYGNRQVSSRQELEELP
                     FSSDADLEERIFQVCLAAGFEADFQSWRQALKAESVYHFFHDIIPVFEKLGHVDLSDK
                     LEELYSLASPQVQIASKGGLLEIQFDFQNIAQEEIDQAMQALVANQDFYIDSSNQVYF
                     FDEETKKIRQNLQELGQFELKDGTLQARKSLAYSLAHLFEGRDRVSFSQEFQNLAQDL
                     THPEDFPLQATQVKADLRDYQEKGIGWLQMLHHYGFGGILADDMGLGKTLQTIAFLTS
                     QVTKESRVLILAPSGLIYNWADEFQKFAPQLDVAVVHGLKASREEILAESHQIYVTSY
                     ATFRQDSEFYQGMAFDFLFLDEAQVMKNAQTKIAQTLRQFVVPSVFALSGTPIENHLG
                     ELWSIFQIVMPGLLPSKKEFMKLPAERVAQFIKPFVMRRKKEEVLTELPDLIEVVYKN
                     ELEDQQKAIYLAQLQQMRDHLAQVSEQEFQRSRVEILSGLMRLRQICDTPALFMEDYQ
                     GASGKLDSLRDLLVQVADGGHRVLIFSQFKGMLEKIEQELPDLGLTSFKITGSTPAKE
                     RQDMTKAFNQGERDAFLISLKAGGVGLNLTGADTVILVDLWWNPAVEAQAIGRAHRMG
                     QEETVEVYRLVTKGTIEEKIQELQEQKKHLVSQVLDGTESRGSLTLAEIREILGISEA
                     ST"
     gene            28990..29607
                     /locus_tag="VQU30_000856"
     CDS             28990..29607
                     /locus_tag="VQU30_000856"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000808222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cystathionine gamma-synthase"
                     /protein_id="HET2446990.1"
                     /translation="MKQERFPLVSDDEVMLTEMPVMNLYDESDLISNIKGEYRDKNYL
                     EWAPIAEEKPVKPIEKQVGKPKKAPLGVKKEGKSYAEVAREEARADLKKKRSANYLTQ
                     DFSLARRHSQPSLVRQGNQPTTPFQKENPGEFVKYSQKLTQSHYILAEEVHSIPTKNE
                     EVSAPAPKKNNYDFLKKSQIYNKKSKQTEQERRVAQELNLTRMTE"
     gene            29617..30951
                     /locus_tag="VQU30_000857"
     CDS             29617..30951
                     /locus_tag="VQU30_000857"
                     /EC_number="6.3.2.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015511317.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramate--L-alanine ligase"
                     /protein_id="HET2446991.1"
                     /translation="MSKTYHFIGIKGSGMSALALMLHQMGHKVQGSDVEKYYFTQRGL
                     EQAGITILPFDEKNLDGDMEIIAGNAFRPDNNVEIAYADQNGISYKRYHEFLGSFMRD
                     FVSMGVAGAHGKTSTTGMLSHVLSHITDTSFLIGDGTGRGSANAKYFVFESDEYERHF
                     MPYHPEYSIITNIDFDHPDYFTSLEDVFNAFNDYAKQITKGLFVYGEDAELRKITSDA
                     PIYYYGFEAEGNDFVASDLLRSTTGSTFTVHFRGQNLGQFHIPTFGRHNIMNATAVIG
                     LLYTAGFDLNLVREHLKTFSGVKRRFTEKIVNDTVIIDDFAHHPTEIIATLDAARQKY
                     PSKEIVAVFQPHTFTRTIALLDDFAHALNQADAVYLAQIYGSAREVDHGDVKVEDLAN
                     KINKKHQVITVENVSPLLDHDNAVYVFMGAGDIQTYEYSFERLLSNLTSNVQ"
     gene            30961..31425
                     /locus_tag="VQU30_000858"
     CDS             30961..31425
                     /locus_tag="VQU30_000858"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000405282.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HET2446992.1"
                     /translation="MEIPIKIIQASKSDLPEIGALQTSSFPAEKQQLSHILEESIRKC
                     ADTFLLARDENQLLGYILSSPQSDNPQYLKVHSLVIESDHQRQGLGTLLLAALKEVAV
                     DLDYKGIRLESPDELLSYFEMNGFVDEEATLLYATSQGYSMIWFNPFYLEEQ"
     gene            31422..31916
                     /locus_tag="VQU30_000859"
     CDS             31422..31916
                     /locus_tag="VQU30_000859"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000702438.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HET2446993.1"
                     /translation="MKIRQARLEDLDRIVELEFENFSVEEAIPPSVFEAHLREIQTSF
                     LVAEKEGRIMGYIEGPVGLHRHLQDQSFTEEIKDYSHEPGGYISVTCLSIAKEAQGLG
                     LGQKLLTALKEVALEDERDGINLTCHDYLIAYYEKHGFVNEGQSQSTFAGETWYDMVW
                     EMKK"
     gene            31997..33646
                     /gene="mltG"
                     /locus_tag="VQU30_000860"
     CDS             31997..33646
                     /gene="mltG"
                     /locus_tag="VQU30_000860"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001291636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endolytic transglycosylase MltG"
                     /protein_id="HET2446994.1"
                     /translation="MSEKSREEEKLSFKEQILRDLEKVKGYDEVLKEDEAVVRTPANE
                     PSAEELMTDSLSTVEEIMRKAPTVPTHPSQGVPASPADEIQRETPGVPSHPSQDVPSS
                     PAEESGSRPGPVRPKKLEREYNETPTRVAVSYTTAEKKAEQAGPETPTPATETVDIIS
                     DTSRRSRREGAKPVNPKKEKKSHVKAFVISFLVFLALLSAGGYFGYQYVLDSLLPIDA
                     NSKKYVTVGIPEGSNVQEIGTTLEKAGLVKHGLIFSFYAKYKNYTDLKAGYYNLQKSM
                     STEDLLKELQKGGTDEPQEPVLATLTIPEGYTLDQIAQAVGQLQGDFKESLTAEAFLA
                     KVQDETFISQAVAKYPTLLESLPVKDSGARYRLEGYLFPATYSIKESTTIESLIDEML
                     AAMDKNLSPYYSTIKSKNLTVNELLTIASLVEKEGAKTEDRKLIAGVFYNRLNRDMPL
                     QSNIAILYAQGKLGQNISLAEDVAIDTNIDSPYNVYKNVGLMPGPVDSPSLDAIESSI
                     NQTKSDNLYFVADVTEGKVYYANNQEDHDRNVAEHVNSKLN"
     gene            33717..34199
                     /gene="greA"
                     /locus_tag="VQU30_000861"
     CDS             33717..34199
                     /gene="greA"
                     /locus_tag="VQU30_000861"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018370745.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription elongation factor GreA"
                     /protein_id="HET2446995.1"
                     /translation="MAEKTYPMTLEEKEKLEKELEELKLVRRPEVVERIKIARSYGDL
                     SENSEYEAAKDEQAFVEGQISSLETKIRYAEIVNSDAVAQDEVAIGKTVTIQEIGEDE
                     EEVYIIVGSAGADAFAGKVSNESPIGQALIGKKTGDTATIETPVGSYDVKILKVEKTA
                     "
BASE COUNT        10715 a         6373 c         7776 g         9483 t
ORIGIN      
        1 ccaaggtgaa cgcggtttaa ctggagctaa aggtgaaaaa ggggaccaag gtgaacgcgg
       61 tctcactgga gcccaaggtg aaaaaggaga ccgaggcgaa cgtggtttaa ctggagctaa
      121 aggtgaaaaa ggagcccaag gtcaggcagg tcgtgacggt gtaactccaa ccgtaaccgt
      181 taaagataat aaaaatgacg gcactcatac tatcactatt aacgacggta gaggtaatgt
      241 tacaagtact gttgtaagag atggtttcga tggcgcaagt ccattagttg cgactcaacg
      301 aaatgacgca gataagacaa caactgttat cttctattac gataaaaatg gaaacaatga
      361 attagatgct tctgataaga aattaaaaga agttgtaatt gcagatggtg ctaaaggtga
      421 aaaaggggac aaaggtgaac aaggtcttca agggcgtgat ggtgaacaag gaccaaaagg
      481 agaagatggg aaaaccccaa cagttaaagt aactgatggt caagatggaa cgcatacaat
      541 tacaattaac gatggtaaag gtggtataac tactacagta gtaagagatg gatttgatgg
      601 tgcaagccct cttgtttcta ctcatagaaa tgaagcagat aaaacaacaa ctgttatttt
      661 ctattatgat ctaaatgata ataatcaatt tgatgaagga gatacaaaac ttaaagaagt
      721 tgttatcgca gatggaaaac aaggaccaaa aggtgacaaa ggtgataacg gaaaagatgg
      781 attcacacca gaagtaacag ttacagataa caataacgga acacacacca tcacaatcac
      841 acaaccagac aacagaccat cattaacaac aatcgttaaa aacggtgaag atggaaaaac
      901 accaaaagtc aaagcagaac gagatgatgc gaagaaacaa acaacattaa cattctacat
      961 tgacaaagat ggagatggaa gttacacagc aggaaaagac gagttagttc aaacaacagt
     1021 agttaaagac ggacaagacg gagctgcagg agcatctgga cgtgatggaa aagaagtatt
     1081 aaacggaaaa gtagacccaa caacagaagg taaagatgga gacacattcg taaatacaca
     1141 aacaggagat gtattcgtta agaaaggtaa cacttgggaa ccagcaggaa acatcaaagg
     1201 accgaaaggt gacaaaggtg cagatggtgc caagggtgaa aaaggagccc aaggagaacg
     1261 cggcctgact ggagcgcaag gtgtcaaggg tgaaaaggga gatcagggtg aacgcggtct
     1321 aactggatct aaaggtgaaa aaggagacca aggtgaacgc ggtttaactg gagcgcaagg
     1381 tgccaaaggt gacaaaggtg aacaaggtct tcaaggtcgt gatggagctc aaggaccaaa
     1441 aggcgcagat ggacaaagag gaccagcggg accacaagga ccaaaaggag aacaaggtaa
     1501 tccaggaact ccaggtaaag atggaaaatc tctaattgct gttaaaaatg gaactgaaac
     1561 aaaagtctat gtagaggatc cggctagacc aggacaacca cttaatccaa accaaccatt
     1621 agcaactatc actgatggaa gaaacggtac taatggacaa tcaccaacaa ttacagcgac
     1681 acgaagtgtg caaaatggca aaaatggtgt attagtaaca attacaccag taggaggtcg
     1741 tccacaaaca acatttgtag aggatggaca aaagggtgct gatgggaaaa ccccaacagt
     1801 aacaataact gaggggcaaa acggcacaca tacattaacg gttcataatc caggaagtcc
     1861 agatgtgaca actacgatcc gtgatggagc tacaggacaa gcaggtcgtg atggtaaaga
     1921 tgtattaaac ggaaaagtaa atccacaacc aaaccaaggt aaaaatggag ataaatatat
     1981 taataccgaa accggtgatg tctatgttaa aaacaatgga aactgggata aagaaggcaa
     2041 catcaaaggc cctaaagggg acaaaggtgc agatggtgct aaaggcgaaa aaggagacca
     2101 aggcgaacgc ggcctaactg gagcgcaagg agctaaaggt gcggatggcg cagtaggtcg
     2161 tgatggacgt gacggtaaag acgtgttgaa cggcaaagct aacccagaag cacatcaagg
     2221 taaagacggc gataaatacg ttaatacaga aacaggcgac gtcttcgtta agaataacgg
     2281 caactgggat aaagagggca acatcaaagg ccctaagggt gacaaaggtg aacgcggaga
     2341 agatggtaag actccagaag taactgtaac tccaggtaaa gatggccata gtactgacat
     2401 tacattcact gttccaggta aagatccagt tacagtaaat gttaaggacg gagaaaatgg
     2461 tctgaacggt aaaactccaa aagttgattt acttcgtgtc caaggaaaaa acggaaatcc
     2521 atctcataca attgtgacat tctatacaga tgaaaacaat gacggcaaat atacaccagg
     2581 aactgatgaa cttctaggtt cagaaatgat taaagatggt gctaaaggcg cggacggacg
     2641 agatggtaaa tcattgctta ctgtcaagga tggtaaagaa actaaagttt accaagaaga
     2701 tccagctaac ccaggacaac cattaaatcc agaaaaacca cttgcggtaa ttagagatgg
     2761 agtagatgga aaatcaccta cagttacagc tgttcgtaaa gatgaagcag ggcataaagg
     2821 tgtagaaatc actgttgata accatgatgg ttcacaacca actacagtct ttgttcaaga
     2881 tggtgctaag ggagaaactg gtgcaaccgg tcaggatgga caaactccta caatcactac
     2941 tcaacgtgga caagatggcc aaagcactgt tgtaactatc acaacatcag gtaaagatcc
     3001 agtaaccttc actgtaaaag atggtaagaa tggtaaagat ggccgtgcac cgaaaatcaa
     3061 agtagaagat attacttcac cttcaagaat tagacgcgat acagatgctg ctgcaactcc
     3121 aacgcgtaac ggtatccgtg ttacagttta tgatgatgtt aatgacaatg gggtatacga
     3181 cgaaggtgtc gataaagtat taaatagtaa agatatttat aacggtatag atggacgtga
     3241 tggttcagct ccaactatta ctacaaaaga taatggagat ggaactcaca ctatcacagt
     3301 tcaaaaccca gatggttctg aatcaacaac agttgttaaa gatggtaaag acggtaaaac
     3361 tgcgaatatc actacaacag aaaacccaga tggaagccac acaattacgg tgacaaatcc
     3421 agatggttca actaaagaaa ctgttgttaa aaacggtaaa gacggtaaga ctcctaaagt
     3481 tgaagtaacg gataacaacg atggaactca tactgttaaa gttacagatg gagacggcaa
     3541 tgttaccaac gctatcatca aagatggtaa agacggtaaa gctgcaacag caacaactac
     3601 tgaaaatcca gatggaagcc acacagtaac aatcactaac ccagacggaa ctaagaatga
     3661 gtttgttgtt aagaatggac gtgacggtgt tgacggacgt actccaaccg catctgttcg
     3721 tgataatgga gacggaagtc atacaatcgt tattacaaat ccagaaggtg tgacaactga
     3781 aaccacagtt cgtgatggta aatcaccaaa agtgactata actgatgaac aaaatggaac
     3841 tcataagatc tctgttctaa atggtgacgg aacaactaca acaactacag ttcgtgatgg
     3901 tagagaacca aaacttgaag ttattgataa caacgatggt tcacacacta ttaaagtgac
     3961 aggtgctgat ggtaaaggaa cgacaactac aatctttgat ggtaaatcac caaaagcgaa
     4021 catcgttgat aacggagatg gaactcatac attaacaatc gtagattctg atggtcgtga
     4081 atacaaatct attatcaaag atggtaaaga cggcaaagat agcgtttcac caactgtaac
     4141 tgttaaaaat aataacgatg gaactcacgt tgttacaatc actaatccag atggaagtaa
     4201 gacagaaatg gtgattaaag acggtaaaga tggtaaatca ccaaaagttt ctgttgaaga
     4261 taatggtgat ggtagtcata caatcacaat catcaattct gatggaactg tgacaaaaac
     4321 agttattaaa gatggtagag atggacgtga tggtcgagac ggcaaagacg gtaaagacgg
     4381 taaagatgga aaatgtggat gccaagacaa accagtaaca ccatcaaatg acaaaccagt
     4441 tcctccaaca ccaaatgtgc cgacaccaga agtaccggtt aaacctgtgc cagcgcaacc
     4501 aacaccaaat gtaccgacac cagaagtgcc agtacaacca actccagctg ttccaacacc
     4561 agaagtaccg gttaaaccag taccagcggt tccagaacaa ccagtagtac caacaccggc
     4621 tcaaccagca actccagtaa atgctaaccc agtagcacca actacaggta aagaaaaccg
     4681 tggggacaaa ttacctgaaa ctggaagcca atctgattat atctctgttc ttttaggtag
     4741 cggtattcta ttgagcctat atgtaggacg aagaaaagaa gcttaatcag ccaaaagcag
     4801 tcactaattt ctcgaaagaa gatgataagt gatagatctc gaatgaaaga atattcttag
     4861 aatgattttc ctatgatgga aaagactgct aaaaaccttg agtggtaacg ctcaaggttt
     4921 ttttggatgg ctgatgtttg tctgaaaatc ttgattgaga aataaaaagc caccctatta
     4981 ggtggctata attgatttag actttctaaa attttctatt ttttactgaa tcgcttcgac
     5041 caagtcttga gcttgttttt caagtgagtt taggactgtt tcttcaagaa ccaattttcc
     5101 gtctgcccag gcagagtcat taacacgtgc agcagtgaaa tcaccaacgc cttgtgtacg
     5161 gataaatggc aagaggtctt tgtagatagc gaaaagttga tcgtgccctg cattggctac
     5221 agatgatacg gtgacaaact tgtcttgaag ggcagaaacg ccacgcgtat cagacaagtc
     5281 aagggcacga gatagccagt caagcaagtt ttttactgta ccagggatag agaagttgta
     5341 gactggagag aaaatccaga tagcatccgc aacgagaact gcttcacgag cagcagctac
     5401 agctggatgt gttggaactt ccaaatcttg gctgaagaga ggaagggctg aataatcaag
     5461 gtagctaact tccgctttac cagcaagtgc tttctcagct tcgagcgcca tttggtggtt
     5521 gaaagaacct tgacgtagtg atccgacgat aaataatact tttttagaca tgatgtgtct
     5581 cctttttctt caaattttga gaactctctc gttgttataa aatacattac aacaaaacaa
     5641 aagaacttgc aagaaatttg ctcagagttt atttgaaaat tgtaaaattt cggaaactct
     5701 agtcatttgt gactgaaaaa gtaagaactg tttcactttc aaaatcggtt ttgtttgaag
     5761 ggagaaatag aattggttgc tcaaagcaca gctttgaggt tgcagataaa gctgacgtgg
     5821 tttgaagaga ttttcgaaga gtattcttat attcacttgt aataaagctt aatagatggt
     5881 aaaatagacg agtgaaaaaa agacaaaaca aagcaaaaaa taatctactg tggcagtatg
     5941 gtctagggat gacgattttg tttgtggtta tcagtgcttc ctttctgtat atggtttctc
     6001 ttagcatgaa accctatcaa acagctaaaa gtgaaggaga aaaattagct cagcagtatg
     6061 caggattaga gcaggccgat caggttgatt tatacaatgg cttggaatct tattacagcg
     6121 ttcttggtcg taataaacag caagaagcac ttgctgttct gattggaaaa gatgatcata
     6181 agatttacgt ttatcagcta aatcagggtg tttcacaaga aaaagcagaa acggtttcta
     6241 aggaaaaggg agctggcgaa attgacaaga ttatctttgg tcgttatcaa gataagccaa
     6301 tctgggaagt caagtcagga tctgattttt atctagtaga ttttgaaaca ggagcattgg
     6361 tcaacaagga gggcctatga aattatccaa ccgtgtttta gaaatggaag aaagtgtgac
     6421 tttggctgct ggagcccgtg ccaaagcact gaaggctgag ggtagagata ttttgtctct
     6481 aaccttgggt gagccagatt tcactactcc caaaaatatc caagatgccg ccattgcatc
     6541 gattcgagat gggcgtgctt ctttttatac agtaacctca ggtctgccag agcttaaggc
     6601 ggcggtcaat agctactttg agcgctttta cggctattct gtagcgtcaa atcaagtgac
     6661 agtcgctgcg ggagccaaat attctctcta taccttcttt atggctgtgg tcaatccagg
     6721 tgatgaagtc atcatcccaa ccccatactg ggttagctat ggagatcagg tcaagatggc
     6781 agaaggcgtt cccgtctttg tttctgctaa ggaagacaat cactttaagg tgaccgtaga
     6841 gcagttagaa gcagctcgca ctgacaagac caaggttttg gtgctgaatt cgccatctaa
     6901 tcccacaggt atgatttaca cccgtgagga actcttggca attggaaact gggctgtaga
     6961 aaatgatatt ctcatcctag cagatgatat ctatggccgc ttggtttata atggtcatga
     7021 gttcacaccg atttctagcc tatcggaagc gattcgcaag caaacagtgg tcatcaatgg
     7081 tgtgtctaaa acctatgcca tgactggttg gcggattggt tatgccgttg gagaagcaga
     7141 cattatcgct gccatgtcca agattgcagg tcaaacaact tcgaatccgt cagcagtagc
     7201 ccaatatgca gcagttgagg ctctatcagg tgagcaagat actgtagaaa gcatgcgtca
     7261 ggcctttgaa gaacgtctta ataccatcta tcccctcctt gcagaagtgc caggatttga
     7321 agtggtcaaa ccgcaagggg ccttctatct cttcccaaat gtcaaaaagg ccatggagat
     7381 gaaaggctac acggatgtga cagactttac aactgttatc ttagaagaag ccgaagtggc
     7441 cttggtaaca ggagctggat ttggagcacc agaaaatgtc cgcctcagct atgcgacaga
     7501 cctagacacg cttaaagaag cagtcgaacg cttgaaagca tttatgggta gtgagaatga
     7561 ttgatcattt tgagattaag gtaaaggatt tacaaatttc agaaggattt tataggagtt
     7621 ttctcgctcc tttggactat aaattggctt ttaagactag ttctctaatt agttttctat
     7681 ccccgaacag ccctcatcct ggtggtgatt tttggctgac tcagggaaca caagatcctg
     7741 ttcattttgc ttttttagca gaaaataagg aagaagttca ggcttgttat gaggctggct
     7801 tagaggcagg tgggcgagac aatggggctc ctggttatcg aagtgagcat ccgatttact
     7861 atgctgcttt tatgattgac ctggatggga acaatataga ggtggtttgc cataaagaat
     7921 aaaaaagaaa aggaaaaata atgacaaaac gtgtaacgat tattgacgta aaagactatg
     7981 ttggtcagga agtgacgatt ggcgcttggg ttgccaacaa atcaggaaaa gggaaaatcg
     8041 ctttcttaca attgcgtgat ggaacagcct tctttcaagg tgtggctttt aaaccaaact
     8101 ttgtcgaaaa atttggtgaa gaagtgggac ttgagaagtt tgatgttatc aaacgcttga
     8161 gccaagaaac gtctgtttat gtgacaggta ttgtcaaaga ggacgaacgt tctaaatttg
     8221 gctatgagtt ggacatcaca gacatcgaag tgatcggtga atctcaagac tacccaatca
     8281 caccaaaaga acacggaaca gactttttga tggataaccg tcacttgtgg ctacgctctc
     8341 gtaagcaagt agctgtgttg caaatccgta acgctattat ctatgcaact tatgagttct
     8401 ttgacaagaa cggttttatg aagtttgaca gcccaattct ttcaggaaat gcggcagaag
     8461 attctacaga actctttgaa actgactact tcggaacgcc agcctacttg agccaatcag
     8521 gtcaacttta cctagaagca ggggctatgg ctcttggtcg tgtctttgac tttggtccag
     8581 ttttccgtgc tgaaaaatca aaaacacgcc gtcacttgac tgagttctgg atgatggatg
     8641 ctgagtactc atacttgaca catgatgagt cgcttgactt gcaagaagct tatgtgaaag
     8701 ctcttctaca aggtgttctt gaccgcgcgc ctcaagcctt ggaaaccttg gaacgtgata
     8761 cagaactctt gaaacgctac attgcagagc cattcaaacg tatcacttac gatcaagcca
     8821 ttgacctctt gcaagagcat gaaaatgatg aagatgctga ctacgagcat cttgagcatg
     8881 gtgatgactt tgggtcacca cacgaaactt ggatttcaaa ccactttggt gtgccaacat
     8941 ttgtcatgaa ctatccagca gccatcaagg ccttctacat gaaaccagtt cctggaaatc
     9001 cagagcgcgt gctttgtgca gacttgcttg ctccagaagg ctatggagaa attatcggtg
     9061 ggtctatgcg tgaggaagat tacgatgccc ttgtcgctaa gatggatgaa cttggcatgg
     9121 atcgtacaga atatgaattc taccttgacc ttcgtaaata cggtacagtt ccacacggag
     9181 gatttggtat cggtatcgaa cgtatggtaa ccttcgcagc aggaacaaaa catatccgtg
     9241 aagctattcc attcccacgt atgttgcacc gtatcaaacc ataagaacag gaaaacgccc
     9301 atgtggcgtt ttttcgaatt ctagtgtttt tacttgcgta aaaaaaattt ttctagtata
     9361 atagtttatt gtgagcgaac ctcacttacc ccttgcaaag tcttggggtc attagaccaa
     9421 aaggaggaac atatcaatgg ctaaatacga aattctttat atcattcgtc caaacattga
     9481 agaagaagct aaaaacgctt tggtagcacg ttttgactct attttgactg acaacggtgc
     9541 aactgttgtt gaatcaaaaa cttgggaaaa acgtcgtctt gcatacgaaa tccaagattt
     9601 ccgtgaagga ctttaccaca tcgttaacgt tgaagcaaat gacgatgcag ctcttaaaga
     9661 gtttgaccgt ctttcaaaaa tcaacgctga cattcttcgt cacatgatcg tcaaaattga
     9721 cgcgtaagaa ggtaaactat gattaacaat gttgtacttg tagggcgtat gacacgtgac
     9781 gctgaattgc gttatacccc atcaaatgta gcagttgcga cttttactct tgcagtaaac
     9841 cgtacattta agagtcaaaa tggtgaacgt gaggctgatt ttatcaatgt cgttatgtgg
     9901 cgccaacagg ctgaaaatct tgctaactgg gctaaaaaag gctcacttat cggggtgaca
     9961 ggtcgtatcc agactcgtag ttacgataac cagcaaggac aacgtgtcta cgtgacagag
    10021 gtcgtggctg agaatttcca aatgttggaa agccgtagtg tgcgtgaggg tcacacaggt
    10081 ggagcttact ctgcaccaac tgcaaactat tcagcaccta caaattcagt accagacttt
    10141 tcacgtaatg aaaatccatt tggagcaaca aacccattgg atatttcaga tgatgattta
    10201 ccattctaat ggacaactaa acttataaag gagaaaaaac atggctcaac aacgtcgtgg
    10261 cggattcaaa cgccgtaaaa aagttgatta catcgcagca aacaaaattg aatatgttga
    10321 ttacaaagat actgagcttc ttagccgttt cgtttcagaa cgtgggaaaa tccttcctcg
    10381 tcgtgtaaca ggaacttcag ctaaaaacca acgtaaagta acaacagcta tcaaacgcgc
    10441 tcgcgtaatg gctttgatgc ctttcgtaaa cgaagattaa agaaaagacc cggttgggtc
    10501 tctttttcat gaacttgaaa acaagaaagc gaattaagac cccaacgggt cttttttcac
    10561 aagctttgaa atgagagagc gagttaggct cagtggctcc ctttttacga gtttgaaaac
    10621 aagagaacac attaaaagca cgatggagct ttttcataaa tatgtctttt ttttcatcca
    10681 agaaattaaa ataaaaatga taaacttttt gaaaataggg gatttgccta ctttatgata
    10741 taatggaaag agttagattg aaagaggtag tgagatggac gcgaaattaa gatacaaggc
    10801 aaagaagatc aagattgtct tttttgatat tgatgataca ttgcggaatt caaagacagg
    10861 gtttattcca actacaattc ccactgtttt taaacagttg cgtgaaaaag gaattttaac
    10921 aggaatcgcc tctggacgtg gcatttttgg tgttgttcca gagattcgtg atctcaaacc
    10981 tgactttttt gtaactttga atggggctta tatcgaagat aaaaaaggtc aggtcattta
    11041 tcagcatcag attgaaaagt catatgttga ggagtatatc tcttgggcta agcaagaagg
    11101 aattgagtat ggcttggttg ggagtcatga tgccaagttg tcgactcgca ccgatatgat
    11161 gagtgaagct atcaatccaa tttatcccga cttagatgta gatcccgatt tccatgaaaa
    11221 agaagatatc tatcagatgt ggacttttga agataaggga gatgacttgc acttgcctga
    11281 cagtctctca gacaaacttc gcatggttcg ttggcatcaa cattcgtctg atattgtgcc
    11341 gatttcaggc tccaaagcga cgggggtgga aaaggttgtg gaacaccttg gcttgaaacc
    11401 agagaaggtc atggtttttg gagatggtct caatgacttg gaactctttg attatgctgg
    11461 aatcagcgtt gccatgggaa tttctcatga taaaatcaaa gaaaaagcag attatattac
    11521 aaaaacatta gaagaagatg gcatttttga tgccttagaa gtatttggta tggtagaaaa
    11581 agaattgcat tttccacaag tagacattga aacagtagaa ggtcctcttg cgactattaa
    11641 gaccaatcac ggagacttac gtatcaagct tttccctgaa catgctccta aaacagtggc
    11701 taactttgta tctctttcaa aagatggcta ctatgatggt gtcattttcc accgtattat
    11761 caaggacttt atgatccaag gtggagaccc aactggaact ggtatgggtg gcgagtcaat
    11821 ctacggcgaa tcttttgagg atgaattctc agaagagctt tacaatatcc gtggtgctct
    11881 ttccatggca aatgctggtc caaataccaa cggcagccag ttctttatcg tgcaaaacca
    11941 acacctacct tattctaaga aagaaattac tcgtggtggt tggccagaac cgattgcaga
    12001 aatctatgcc aatcaaggtg ggacacctca cctagaccgc cgtcacacgg tttttggtca
    12061 gttagctgat gaagcatctt acgctgtctt ggatgtcatt gctgctgttg agacaggagc
    12121 tatggacaag ccagttgaag atgttgtaat tgaaactatt gaaatcgagg actaagatga
    12181 aaatcggtga taagctaaag gggcgtatta cagggattca gccctacggt gcctttgttg
    12241 agttagagac gggtgatacg gggctgattc acatttcaga aattcggaca ggatttattg
    12301 aaaatattca tgaaaccttg aaagtcgatg aagaggttca agttcaggta gtggatttag
    12361 atgaatttac ggggaaagcc agtctttcta tccgcacttt ggaggaagaa aagtaccagt
    12421 ttcctagacg gagacgcttt tcaagcgacc gctttaacta cggttttgct ccctttcgac
    12481 gaatgctacc aatctggact ggagaagccc tgcaccattt aaaaaagaag aagtagttta
    12541 gagttttata ttttttgtaa tgttaatata aatttgctat aataggacca tggaagaaga
    12601 acaattatta aaatcaggag agcgcattaa ccagctcttt tcgacagata tcaaaatcat
    12661 tcaaaataga gaggttttta gctattcggt ggatagtgtt ctcttatcac gatttccacg
    12721 ttttcctaag aaggggttga ttgtggattt ctgtgctggg aatggagcag tggggctttt
    12781 tgctagcact cgtactcaag cacagatatt gtctgttgag attcaggagc gtttggcgga
    12841 tatggctgaa cgctctgtcc gtttgaatgg attagaggag caaatgcagg tcatctgcga
    12901 tgatttgaaa aatatgcctg ctcacattca ggggagtaag gtggatatga ttttgtgtaa
    12961 tccaccctat ttcaaggtgg atccttattc taatctgaac gagagtgaac attatctctt
    13021 ggctcgacac gaaatcacga ctaatttgga agaaatctgt catagtgccc agagtattct
    13081 caagtctaat gggcgtttgg ccatggttca tcgtcctgat cgacttctgg atattttgga
    13141 tacgttaaaa cgacataatc tagcccctaa gcgcctgcag tttgtttatc caaaaagaga
    13201 aaaggaagcc aatatgcttt tgattgaggc gatcaaggat ggctcaacaa gtggctttaa
    13261 ggtcttacct cctttgattg tccacaatga tgatggctct tatacgcccg aaatcgaaga
    13321 gatttattat ggatcataag gcttatatgt acgttctgga gtgtcgtgat ggatcctact
    13381 atataggcta tacgactgat atgagaagac gcctcgctat ccacaatagt gggaagggag
    13441 ccaaatatac acgagcacgc ttgccagtca aacttatcta tgctcaaggt tttgccagta
    13501 aggaagaagc catgtcggct gaagctcttt tcaagcgtaa gaagaggcca cagaaggaag
    13561 aatttttatc tgaaaatcaa gatagaaatt tactcagtta ttttgaagaa tcgtggggag
    13621 tcctttgact cctcttacct ttgtcaaaaa gcgaaaaaaa tgctacaata aagaaaataa
    13681 acaaaatgag gtattatcat gtccaagatt ctagtatttg gtcaccaaaa tccagactca
    13741 gatgccatcg ggtcatctgt agcttttgcc taccttgcaa aagaagctta cggtttggat
    13801 acggaagctg ttgcccttgg aactccaaat gaagaaacag cctttgtctt gaactatttt
    13861 ggtgtggaag caccacgtgt tatcacttct gccaaagcag agggggcaga gcaagttatc
    13921 ttgactgacc acaatgaatt ccaacaatct gtatcagata tcgctgaagt agaagtttac
    13981 ggtgttgtag accaccaccg tgtggctaac tttgaaactg caagcccact ttacatgcgt
    14041 ttggagccag ttggatcagc gtcttcaatc gtttaccgta tgttcaaaga acatggtgta
    14101 gctgtgccta aagagattgc aggtttgatg ctttcaggtt tgatttcaga tacccttctt
    14161 ttgaaatcac caacaacaca cccaacagat aaaatcattg ctcctgaatt ggctgaattg
    14221 gctggtgtaa acttggaaga atatggtttg gcaatgttga aagctggtac caacttggct
    14281 agcaaatctg ctgaagaatt gattgacatc gatgctaaga cttttgaact caacggaaat
    14341 aatgtccgtg ttgcccaagt gaacacagtt gacatcgctg aagttttgga acgccaagca
    14401 gaaattgaag ctgcaatgca agctgccaac gaatcaaacg gctactctga ctttgtcttg
    14461 atgattacag atatcgtcaa ctcaaactca gaaatattgg ctcttggtgc caatatggac
    14521 aaggtcgaag cggctttcaa tttcaaactt gaaaacaatc atgccttcct tgctggtgcc
    14581 gtttcacgta agaaacaagt ggtacctcaa ttaactgaaa gctttaatgc gtaagatttt
    14641 gggtgtcagc tcaaaatcgg aaagtctagt ttgccttata tcgaaaggag tttcggctcc
    14701 tttttttcta ggagtgaagt atgttagaaa atggcgattt gatttttgtg agagatgggt
    14761 cagacatggg acaggccatc cagacttcca caggtaacta tagccatgtt gccatttatt
    14821 tggatgggat gatttatcat gctagtggac aggctggtgc tgtctgtcaa gaaccggcag
    14881 acttctttga gtccaatcat ttgtacgacc tctatgttta cccagaaatg gatatccagt
    14941 cggtgaagga aagagcttgc agacatcttg gagcacccta caatgcttct ttctatccag
    15001 atgcagctgg tttctactgc tcccagtata tagcagaaat cctacctatt tttgaaacta
    15061 ttcctatgaa atttggagat ggggaacagg agattagtga tttttggagg gagtattaca
    15121 tagaactagg tctgcctgtt cctctgaacc aagctgggac caatcctagt cagttggcag
    15181 catcgcctct gttacaatgt aaagaaagga atcttcatga ttcagatttt taattcatct
    15241 cgtttgacga gacagccatt tttggagaat tgatccgcta tctggaccag tatgaggatg
    15301 tgattctacg ggaaattaag gctcaatttc cagatgttgc agttgataaa ctcatggaag
    15361 agtatataaa ggcaagcttg attctacgtg aaaataagcg ctattacctc aattttccta
    15421 cgcttgaatc acttgatagt cttgaactgg atcaagagat ttttgtcaga gaagctagtc
    15481 cggtctatca agccttgttg gagcagagtt ttgagacgga attgcgcaat caaatcaatg
    15541 cagctatttt agttgaaaga cggactttgc gcgcattaaa atgaccctgt ccaattattt
    15601 ttacaaggtc aaacagcagt atcctttgac agaaaaacag caggagctct atgacatttt
    15661 aggagatgtt aatcctgagt atgcactcaa gtatatgacg gcttttttgt tgaaatttct
    15721 caaaaaagac cagcttatgc agaaatgccg tgatatcttt gtggacagtt tggttgtctt
    15781 aggctatatt gtgcaaaatg aagatagaaa gtatgagttg gctatcgatt ttgataagga
    15841 gagattaact ttctacttag cgtgatttct tgtttctgag cacattgttt gactttcctt
    15901 agtattcggt ataaactata tgtaaccggt aacacatatc ggaataaact aaaggagaca
    15961 atcatatgtc acttgaaaac aaattggaac aagcaacagg cgctgtcaaa gaaggttttg
    16021 gtaaagttac tggagacagc aagacagaac ttgaaggagc tgttgaaaaa acagttgcta
    16081 aggcaaaaga cgttgtagaa gacgcaaaag gtgctgtaga aggtgccgtt gaaggtttga
    16141 aaaacgtttt tactaaataa taggaaaaaa tcaagggttt cattttccct tgattttttc
    16201 tattcttata aataattttc tgcgacggct gtatctcctg ggtaggattc tttcttgccc
    16261 tggatgattt ggtaacaatc ggctccctta cccgcaataa taactgcatc taattcgtga
    16321 tttgtgatag ccattgccgc cttgatggct tcttggcgat ccgcaatctt ttcaacagga
    16381 tgattgatgt agctactaat ttcatctgca atggccattg ggtcttcata gttagggtca
    16441 tcagcagtca gaaagacttg aatctcaggg tgttgattga ggaggaggcc aaagtcctta
    16501 cgacgacttt ctcccttgtt tcctgttgat cccagaacca gagcaatctt tccggtttga
    16561 tgagtttcaa ccacattgat gagttttttc agactatccc cattgtgggc atagtcgatg
    16621 aagaccttgg ctccattttt ctgagtgagg acttccatac gaccaggaac gcgggttgca
    16681 gcgatgcctt ttttgatgtc ctcaagactt gctccgagac ggagacaagc aagtccagca
    16741 gcaactgcat tttcttggtt gaagttgcca atgagttgga tatcataatc tccagcgagt
    16801 ttacccgtag ctgaaaagct aaaggctttg gaattctcga tttggttatc aaattggcta
    16861 ccatagaaat catggtcttg atcttcaacc tgttctttca agactgagaa gtggtccatg
    16921 tcactgttaa tgatgactgc tcggctattt tccatcaaga gacgcttgtg gtagaaatag
    16981 tcttcaaagc tagggtgttc aatcgggccg atatggtcag gagtgatgtt aagaaagact
    17041 cctacatcaa aggtcagtcc atagactcga tggactagat aggcttgact ggagacttcc
    17101 atgatgaggt gggtacggtc attttgcaca gcctgattca tcatgtcaaa gaggtcaata
    17161 ctctcagggg ttgtcaacgc tgacttaaag aaagtctcgc catcaagagt tgtgttcatg
    17221 gtcgacaaca tagcaggtct atgcccttga gataagatgt tataggcgaa ataggttgct
    17281 gttgtcttac ccttagtacc agtaaaggca aggagtttga gtttctcttg tggattacca
    17341 tagaactcca tggcaatcaa actcatggct ttctttatat cgttcacaat gatgacaggg
    17401 atatcgactt cgtagtcctt ttcagctaca taccaagcta aaccttgtgt tatagcagaa
    17461 agaaggtatt cttttttaaa ggcagcgcct tttgcaaaaa aaagagtgtc ttctgttact
    17521 tttcggctgt cgtagctgat gctatcaaaa ataactttgc tgtagttgta gtggtaatga
    17581 ccttggtcaa taatttcgcg aaaaaggcca tctttcttta aaatatctaa tacggtttca
    17641 atcttaatca tactttctat tgtaaaccga aagtcgtaaa tttacaagta acaaggaaaa
    17701 gtttataatg gaagataagg agtttttcct agttatcaaa attgaatgag gaatctatgt
    17761 cgcacgaaaa caatcaccag caggcccaga tgttacgggg gactgcttgg ctaacggcta
    17821 gtaactttat cagtcgccta ctcggggctg tttacattat cccttggtac atctggatgg
    17881 gggcttatgc agctaaggca aatggtctct ttaccatggg ttacaatatc tatgcttggt
    17941 tcttgttggt ttcaacagcg gggattccag ttgcggtggc caagcaagtt gccaagtata
    18001 ataccatgcg agaagaagag catagctttg ccctgattcg gagcttctta ggctttatga
    18061 caggactagg cctggttttt gctttagtct tgtatgtctt tgctccttgg ctagcagact
    18121 tgtctggcgt gggcaaagac ttgatcccaa tcatgcaaag cttggcttgg ggagtcttga
    18181 ttttcccgtc tatgagtgtt atccgaggat ttttccaagg gatgaataac ctcaaaccct
    18241 atgccatgag ccaaattgct gagcaggtca ttcgtgttat ctggatgctc ctagcaacct
    18301 ttatcattat gaagctcggt tcaggagatt atctagcagc cgttacccaa tcaacctttg
    18361 ctgcctttgt cggtatggta gccagttttg cagtcttgat ttatttcctt gcccaagaag
    18421 gttcactcaa aagagtcttt gaaacaggag ataagattaa cagtaagcgt ctcttggttg
    18481 ataccattaa ggaagccatt ccttttatcc tgacagggtc tgccatccag ctcttccaga
    18541 ttttggatca gctgaccttt atcaatagta tgagctggtt taccaactac agcaatgagg
    18601 acttggttgt catgttttct tatttctcag ccaatcctaa taaaatcacg atgattttga
    18661 tttctgtagg ggtttcgatt gggagtgttg gtttgccact tttgacggaa aactatgtca
    18721 agggggactt gaaagcagct tctcgtctcg ttcaggacag tctcacccta ctctttatgt
    18781 tcttgctacc agcaacggtt ggagtggtta tggtaggaga acctctttat acggtcttct
    18841 atggtaagcc agatagtttg gctctgggct tatttgtctt tgcagttttg cagtctatta
    18901 ttttaggctt gtacatggtc ttgtctccaa tgcttcaggc catgttccgc aaccgcaagg
    18961 ccgttctcta ttttatctat ggttctattg ccaagctagt cttgcaacta cctaccatcg
    19021 ccctcttcca cagttatggt cctttgattt caacaaccat tgctctcatc attcctaacg
    19081 tcttgatgta tcgggatatt tgtaaagtaa ctggtgtcaa gcgcaaggtg attttgaagc
    19141 gaaccatttt aatcagtttg ctgaccctag tcatgtttct gttaatagga accatccagt
    19201 ggctgttagg atttttcttc caaccaagtg gacgtttgtg gagcttcttt tatgtagctc
    19261 ttgtcggtgc catggggggt ggactttata tggttatgag tctgcgtacc tatttattag
    19321 ataaggtaat aggaaaagcc caagcagatc gcctgcgagc aaaatttaag ctttcgtaag
    19381 gtagcattta taaataaaag gaataagttg aacaatcttt taggagaact tgaagcttat
    19441 tcctttttta gcgtaaaaat agctaaaatt atatttcaaa aatagaaaat gaggcttttt
    19501 tcgatttttt ggaaaaaatc attgactaaa caaactaaac gttgtataat aaaacaaata
    19561 tttaaagcag gaggttccgg aaatgaaaaa gtctaagagc aaatatctaa ccttggcagg
    19621 tcttgtcctg ggtacaggag ttttattgag cgcgtgtgga aattctagca cggcgtcaaa
    19681 aacatacaac tatgtttatt caagtgatcc atctagcttg aactatctag cagaaaaccg
    19741 cgcagcaaca tccgatattg ttgcaaattt ggtagacggg ttattagaaa atgaccaata
    19801 tgggaatatt attccatcat tagcagagga ttggactgtt tctcaggacg gtttgaccta
    19861 tacctacaaa cttcgtaagg atgccaagtg gtttacttct gagggagaag aatatgcgcc
    19921 tgtaactgcc caggattttg tgacaggttt gcaatatgca gctgataaaa aatcagaagc
    19981 cttgtatcta gtgcaggact ctgttgctgg tttggatgac tatatcactg gtaaaacaag
    20041 cgacttttca actgtcggtg tcaaggcact tgatgaccaa acggttcaat atactttggt
    20101 taaaccagaa ctttactgga attcaaaaac acttgcaacg atactttttc ctgttaatgc
    20161 agatttcctg aaatcaaaag gggatgattt tgggaaggcg gatccatcta gtattttgta
    20221 caatggacct ttcttgatga aagcacttgt ctcaaaatct gctattgaat ataagaaaaa
    20281 ccctaattac tgggatgcta agaatgtctt tgtagacgat gtgaaattga cctactatga
    20341 tggtagcgac caagaatcac tggaacgtaa ttttacagct ggtgcttata ctacggctcg
    20401 tctttttcct aacagctcca gctatgaagg gattaaagaa aaatacaaaa acaatatcat
    20461 ctatagtatg caaaattcaa cttcatattt ctttaatttt aacctagata ggaagtctta
    20521 caattatact tctaaaacaa gtgacattga aaagaaatcg actcaggaag cagttctcaa
    20581 taaaaacttc cgtcaggcta tcaattttgc ttttgacaga acatcttatg gggctcagtc
    20641 tgaagggaaa gaaggtgcaa caaagatttt gcgtaaccta gtggttcctc caaactttgt
    20701 cagtatcaag ggaaaagact ttggtgaagt tgtagcctct aagatggtca actatggtaa
    20761 ggaatggcaa ggtatcaact ttgcggatgg tcaagaccct tactacaatc ctgagaaagc
    20821 caaggctaag tttgcggaag ctaagaaaga actcgaagca aagggtgttc aattcccaat
    20881 ccacttggat aagactgtgg aagtaacaga taaagtaggc atacaaggag ttagttctat
    20941 caaacaatca attgaatctg ttttaggttc tgataatgta gtgattgaca ttcagcaatt
    21001 aacatcagat gagtttgaca gttcaggcta ctttgctcaa acagctgctc agaaagacta
    21061 tgatttatat catggcggtt ggggacctga ttatcaagac ccgtcaacct atctcgatat
    21121 ttttaatact aatagtggag gatttctgca aaatcttgga ctagagcctg gtgaggccaa
    21181 tgacaaggct aaggcagttg gactggatgt ctatactcaa atgttggaag aagctaataa
    21241 agagcaagat ccagccaaac gttatgagaa atatgctgat attcaagctt ggttgattga
    21301 tagttcttta gttcttccaa gtgtttcgcg tgggggaaca ccatcattga gaagaaccgt
    21361 accatttgct actgcctatg gtttaaccgg tacaaaaggg gttgaatcat ataaatacct
    21421 caaagtacaa gataagattg tcacaacaga cgaatatgca aaagccagag aaaaatggtt
    21481 gaaagaaaaa gaagaatcca ataaaaaagc ccaagaagaa ttggcaaaac atgtcaaata
    21541 aaatctaatt gtagataagt ttgtgtaaga agtctttgtg cttaaaaacg cataatatca
    21601 ggtatataaa atcctagatg ttatgcgttt tgttatagga agatttatta gattttatcc
    21661 tcaaattgag ttattcccga ctttatccgt tgaaatatta taaggagtat ttatgaaatt
    21721 aaaattatta agagtagata ctaaggtgat tatggggagt ttcttacttg ttctgtctag
    21781 tctacttgct ttgttgcttc cccttatctt aaagggttta atagatggga gttctattga
    21841 aaatataggt tccaaagtat ttcaatcgtt tttgattttt attggtcaag ccttgttttc
    21901 ttctattggt tactatctgt ttagtcaatc gggtgaaaaa aagatagcaa aaatcaggaa
    21961 aaaagtgata gaggggttga tttatgcaga gaaatccttc tttgataaga gccaaagtgg
    22021 ggagttgact tctgccattg tcaatgacac gagtgtcatt cgtgagtttt taattacgac
    22081 tttcccaaat attattctga gtttagttat ggtacttggt tccattgtag tcttatttag
    22141 tcttgattgg aatctttctc tacttttatt catcactctt ccttgtatga tgtttattat
    22201 cttgctcctt tccaatatca gtgaaaagta tagtcgtcgt ttacaggagg aaatcggatt
    22261 tttaacaggg caattgactg aaaagattca agaacatgaa ttaattaaga ctaaccaagc
    22321 agagaaaagt gtacaggatg ttttggataa ttgtattgaa agggtacaaa acaattcact
    22381 gaaatcagat agggttactt cttttgagac cccgtttgct ctcttattta tctttgcgac
    22441 tatagctgtg atgctaacct atgggggtta tcgggtcagc gcaggatata tatctgtggg
    22501 aaccttggtt tcgtttttga tttacctctt tcaattactt aatcctatta gtaatatagc
    22561 taattttgta actgtttatt ctaggagcaa gggatcttca gttgcactgg agaacttgct
    22621 tgcagttcct aaagaaaaat ttgagtgagg aaaatcggta tcaggacaag ggttgaattt
    22681 taaccatgtc tattttggtt atgatgaaaa tcgacctgtc ttaaaggata ttacttgttc
    22741 aattttcaag gggcaaaaaa ttgcttttgt tggaccatct ggatcaggaa aatcaacgat
    22801 tgtgcgtttg ttagagcggt tttataaacc gctttcagga gatattctaa tggagcaatc
    22861 aagtatatat gattttaact taaaagaatg gagaagtaaa atcgcttagt aactgatgat
    22921 gaattgatga aagtgctaga cttagtatca ctaggtgatg agattcgctc catgaaagag
    22981 ggactagata ctgaagttgg tgaacgcgga cgactcttgt caggggggca aagccaaaga
    23041 cttcaaatag ctagagccta cttaaaagat gctgaaattc ttatatttga tgaagccact
    23101 gctaatcttg atgcggattc tgagtatgcg attatcagta gcctctattc tgtattaaag
    23161 gagaagacgg ttgtgattat agcgcatcgt ttgtcaacgg taaaagatgt ggattgtatt
    23221 ttcttcttag aggaggggaa aatcactggc tcaggaactc ataaggaact actggaaaat
    23281 catgagcgtt atgctcgttt tgtgcaggag caaatgatag agtgaaggtg tcttttgaga
    23341 ttcaccattt tatagtctat taaagggagc aggaaaaact ccctttttat atagtttgaa
    23401 actataacta gctcttgaaa agaagaaaat gagttgatga aaataagtgg tacaatagtt
    23461 actatagatt tggaggtatt gtatgagcaa ggaattacac attaacacaa ttttggccca
    23521 ggcgggtatt aagtcagatg aagcgacagg tgcattggtg acaccgcttc atttttcaac
    23581 gacctatcag catccagagt ttggtcgatc tactgggttt gactatacgc gcactaaaaa
    23641 tccaactcgt agtaaggctg aggaagtctt ggcggctatt gagtcagcag actatgccct
    23701 agcgactagc tcagggatgt cagctattgt actggccttt agcgtctttc cagtaggaag
    23761 taaggtcttg gcagtgcgtg atctttacgg tggttctttt cgctggttta accaagtgga
    23821 gcaggaaggt cgtttccatt ttacctatgc caatacagaa gaagagttga ttgccgagtt
    23881 agaaaaggat gtggatgttc tctatatcga aaccccaacc aatcccttga tgttggaatt
    23941 tgatatcgaa aaactagcaa aattggctca tgctaagggt gccaaagtgg tggtggacaa
    24001 taccttctat agccctatct accaacgtcc gattgaagat ggagcagata tcgttctcca
    24061 ttcagcaacc aagtatctag caggccacaa tgatgtcttg gctggagtgg ttgtgaccaa
    24121 tagtttagaa ctatacgaga agctttttta caatctcaat acaacagggg cagtcttgtc
    24181 tccatttgac agctaccagt tgcttcgtgg tctcaagacc ttatctcttc gtatggagcg
    24241 ctcaacagct aacgcccaag aagtggttgc ctttttgaag gattctccag cagttaagga
    24301 agttctctac actggtcgtg gaggcatgat ttcctttaaa gtagccgatg aaacacgcat
    24361 tcctcatatt ttgaacagtc tcaaggtctt ctcttttgcg gaaagtttgg gcggagtgga
    24421 aagtcttatt acttatccaa cgactcaaac tcatgctgat attccagcag aagtacgcca
    24481 ttcttatggt ttgacagatg acctcttgcg tttgtctatt gggattgagg atgctagaga
    24541 tttgattgca gatttgcgcc aagccttaga aggataagac aaagatggga aaatatgatt
    24601 ttacaagcct gcccaaccgt ttagggcacc atacctataa atggaaagaa acagaaacgg
    24661 atagtgaagt tctaccagct tggatagcgg atatggactt tgtggtcttg cctgaaatcc
    24721 gccaagccgt gcaaacttac gcagaccaac tggtttatgg ttatacctat gccagtgaag
    24781 acttaattaa ggaaattcaa aagtgggaag ctacacaata cggttacaac tttgacaaag
    24841 aggctcttgt ctttatcgag ggtgtggtac cagccatctc aacagctatt caaaccttta
    24901 caaaagaagg cgaggcggtt ttaattaaca cgcctgtcta cccacccttt gctcgcagtg
    24961 tcaagttgaa taatcgtaga ttgattacta attccttagt ggaaaaggat ggtctgtttg
    25021 agattgactt tgaccaactt gaaaaggatt tggtggaaga ggaggttaaa ctctatattc
    25081 tttgcaaccc tcacaatcct ggtggacgtg tttgggaaaa agaagtgttg gagaagattg
    25141 gccaactttg ccaaaaacac ggtgttttgt tagtttcgga tgagattcac caagatttga
    25201 ccctctttgg tcacaaacac cagtctttca ataccatcaa tcctgccttc aaaaattttg
    25261 ctatcgtctt gagcagtgcc actaaaacat ttaatattgc tggaacaaaa aattcctatg
    25321 cagtcattga aaatcctaag ttgagactgg ctttccagaa acgcctgttg gccaataatc
    25381 agcatgaaat ttcaggcttg ggttatttgg cgacagaagc tgcctatcga tacggtaaag
    25441 attggctaga ggaactcaag caagtctttg aagaccacat caattatgtg gtggatctat
    25501 ttggaaaaga gactaaaatc aaggtcatga aaccgcaagg tacctacttg atttggcttg
    25561 acttttcagc ctatgacctg actgatgaaa cattgcaaga gttgttgaga aatgaagcca
    25621 aggttatcct caaccgtggt ttggattttg gagaggaagg aagtctccat gcccgcatca
    25681 atatagctat gcccaaatct ctgttgcaag aagtctgtca gcggattgtg gctacttttg
    25741 ccaaacgtta aaaatccagc cttctaggag aaaagtcttc ctagaaggct attttcatag
    25801 gcgaaaatat ggtataataa aaagataagg taaaggtgaa aatatggcta aattgattcc
    25861 ggggaaaatt cgtatcgaag gtgttgccct ttatgaaact ggtaaggttg atatcatcaa
    25921 ggaaaagaac aatcggctct acgctcgcgt tgcagaagaa gaactgcgct atagtttaga
    25981 ggatgatttg gttttttgtg cctgtgattc ttttcaaaag aggggctact gtgtgcattt
    26041 ggcagcgcta gagcattttc tgaaaaatga tgagcgtggt caggaaatct tgtggagtct
    26101 ggaagaaggt catgaagaaa aagaggccgt tgaaaccaag gtgaccttgg gtggcaagtt
    26161 tttgaatcga attttatctc caaaatcaga atgcgcctat gagttatcag ctgtgggtca
    26221 ggtggaagca ggaaccaatc atatcttgtg gactctgaga atcggccaaa tcaatagcca
    26281 aaaatactat gtcattcggg atattccact ttttttaagg attgtcgagc agagaaagtc
    26341 gtatatgatt ggcaagattt atgaggagtc tctttcttgg gaagcctttg atgatgccag
    26401 ccaagaactt ttgactttct tgcacggact aacggaggaa gggctggttc cagacctctt
    26461 tttccaaaac caaggtcggc acctcttttt ccctctgacc ttttttgagc agggtgtgaa
    26521 tttactgatg gccttgcccc attttcaatt tgaccatcaa gtggatagct accaaaccct
    26581 gctttttcag gatatgcatg ctgatgccaa tctatttgcc tttacagtaa cagaatactc
    26641 ggactatttt gaaatggaaa tcagtgagag tcctagggtc aatgtctttt atcagggagc
    26701 agtacttttc cataaaggtc aggtttattt tttaacagac cagcagatgc gtcttctcaa
    26761 ggaaattaaa gcgttacctg tgggtcaaca aggaaagaaa tacctgcaat ttgatagcag
    26821 tgatcgagac aaattggcct cctgtctgac tctttttatc cagatgggca ccgtttcagc
    26881 tccagaacgt ctacaaatca aaacttttgc gccctctttt tactttgaca gggaagaaga
    26941 taatcggatt cgtttagaaa ttcagtttga ttatggaaat agacaggtat ctagccgaca
    27001 agagctagaa gaattaccat tttcaagtga cgcggactta gaagaaagaa ttttccaagt
    27061 ctgtttggct gcgggctttg aagccgattt tcaatcttgg cgtcaggcct taaaagcgga
    27121 gtctgtctat catttttttc atgatatcat tccagtcttt gaaaaactcg ggcatgttga
    27181 cctatcagat aaactagaag agctttatag cctagcgagt cctcaggtgc agattgcctc
    27241 caagggaggt ctcttggaaa tccagtttga ttttcaaaat attgcccagg aggaaatcga
    27301 ccaagccatg caggccttgg ttgccaatca ggatttttat attgattcgt ctaatcaagt
    27361 ttactttttc gatgaagaaa ccaagaaaat tcgccaaaat ctacaggaac tggggcaatt
    27421 tgaattaaaa gatgggacct tgcaggctcg gaaatccttg gcctacagtt tagctcatct
    27481 ctttgaaggg cgagaccgtg tttctttttc acaagaattc cagaatctgg cccaggattt
    27541 gacgcatcca gaggactttc ctttgcaagc aactcaggtc aaggctgact tgcgagatta
    27601 tcaggaaaag ggaattggct ggttgcagat gctccatcat tatggttttg gtgggatttt
    27661 ggctgatgat atgggacttg ggaaaaccct tcagaccatt gcttttttga ctagtcaagt
    27721 gacaaaagaa agtcgagtct tgattctcgc tccgtcgggt ttgatttaca actgggcgga
    27781 tgagtttcag aaatttgccc cacagttgga tgtggctgtt gttcatggtt tgaaagcaag
    27841 tcgtgaggag attcttgccg agagccatca aatctatgtg actagctatg ccaccttccg
    27901 tcaggacagt gagttttatc aggggatggc ctttgacttc cttttcttag atgaggctca
    27961 ggtcatgaaa aatgcccaga ccaagattgc ccagaccttg agacaatttg tggtgccgtc
    28021 ggtctttgcc ttgtcaggaa ctccgattga aaaccatctg ggtgagttgt ggtctatttt
    28081 ccaaatcgtc atgcccggac ttttgccaag caagaaagaa tttatgaaat tgccagcaga
    28141 gcgagtggct cagtttatca agcctttcgt gatgcgacgc aagaaagaag aagttctgac
    28201 tgaattgcca gacttgattg aggtggttta taaaaatgaa ctggaagacc agcaaaaggc
    28261 tatttacctt gcccagttac aacagatgcg agaccatctg gctcaagtgt cagaacagga
    28321 atttcagcga agtcgtgtgg aaattttatc tggtttgatg cgcttgcgtc aaatatgtga
    28381 cactcctgcc ctgtttatgg aagattatca gggagccagc ggcaaactag atagtctccg
    28441 agacctactg gtacaggtgg cagacggcgg acaccgtgtc ttgattttct ctcagttcaa
    28501 gggaatgttg gaaaaaattg aacaagaact gccagacttg ggcctgactt cctttaaaat
    28561 tacgggttca accccagcca aggaaagaca agacatgacc aaggccttta atcaaggaga
    28621 aagagatgcc tttctgattt ccctcaaggc tggtggggtc ggtctgaacc tgacaggtgc
    28681 agatacagtg atcttggttg acctttggtg gaatcctgcg gtggaagcgc aagccattgg
    28741 ccgtgcccat cggatgggtc aggaagaaac ggttgaggtc tatcgcttgg tgaccaaggg
    28801 aaccattgaa gaaaaaattc aggaactcca agaacaaaag aaacatctgg tgtcacaagt
    28861 attggacggc acagagtcac gtggtagtct gaccctagca gaaattagag aaattttggg
    28921 aatttctgaa gccagcactt gaaaaatcaa gacaatacgc tataatgaag tgttgaaagg
    28981 aaatagaaaa tgaaacaaga acgatttcca ttggtgtcag atgacgaggt catgttgact
    29041 gaaatgccag tcatgaatct ctatgatgag tctgatctga tcagtaatat caagggtgag
    29101 tatcgagata aaaattattt agaatgggct cctattgctg aagaaaaacc agtaaaaccg
    29161 attgaaaagc aagtagggaa acctaaaaaa gctcctttag gggttaaaaa agaaggaaag
    29221 agctatgcgg aggtggcgcg tgaagaagcg cgtgcagact tgaaaaagaa acgctctgct
    29281 aactatctaa ctcaggattt cagccttgcg agacgtcatt ctcagcccag tctagttaga
    29341 cagggcaatc aaccgacaac tcctttccaa aaggaaaatc ctggtgaatt tgtcaaatat
    29401 agccaaaaat tgacccagtc tcattatatc ttggcggaag aagttcattc tatccctacc
    29461 aagaatgaag aagtgtcagc acctgctcca aagaaaaaca attatgattt tctaaagaag
    29521 agccaaatct acaataaaaa aagtaaacaa acagaacaag aacgtcgggt tgcccaagag
    29581 ttgaatctga ccagaatgac agaataggga gaaaacatgt caaagacata tcattttatc
    29641 ggaattaagg gatcagggat gagtgccttg gccttgatgt tgcaccagat ggggcacaag
    29701 gttcagggat cagatgttga aaagtactac tttacccaac gcggtcttga gcaggcagga
    29761 attaccattc ttccttttga tgaaaagaat ctagacggtg atatggaaat tatcgctgga
    29821 aatgcctttc gtccagataa caacgtcgaa attgcctatg cggaccaaaa tggtatcagc
    29881 tacaaacgtt accatgagtt tctaggtagc tttatgcgtg actttgttag catgggagta
    29941 gcaggagcac atggaaaaac ttcaacgaca ggtatgttgt ctcatgtctt gtctcacatt
    30001 acagatacca gcttcttgat tggagatggg acaggtcgtg gttcggccaa tgccaaatat
    30061 tttgtctttg aatctgacga atatgagcgt cacttcatgc cttaccaccc agaatactct
    30121 attatcacca acattgactt tgaccatcca gattatttca caagtctcga ggatgttttc
    30181 aatgccttta acgactatgc caaacaaatc accaagggtc tttttgtcta tggtgaagat
    30241 gctgaattgc gtaagattac gtctgatgca ccaatttatt attatggttt tgaagctgaa
    30301 ggcaatgact ttgtagctag tgatcttctt cgttcaacaa ctggttcaac cttcaccgtt
    30361 catttccgtg gacaaaactt ggggcaattc cacattccaa cctttggtcg tcacaatatc
    30421 atgaatgcga cagccgttat tggtcttctt tacacagcag gatttgattt gaacttggtg
    30481 cgtgagcact tgaaaacatt ttccggtgtt aaacgtcgtt tcactgagaa aattgtcaat
    30541 gatacagtga ttatcgatga ctttgcccat catccaacag aaattattgc gaccttggat
    30601 gcggctcgtc agaaataccc aagcaaggaa attgtagcag tctttcaacc gcataccttt
    30661 acaagaacca ttgccttgtt ggacgacttt gcccatgctt taaaccaagc agatgctgtt
    30721 tatctagcgc aaatttatgg ctcggctcgt gaagtagatc atggtgacgt taaggtagaa
    30781 gacctagcca acaaaatcaa caaaaaacac caagtgatta ctgttgaaaa tgtttctccg
    30841 ctcctagacc atgacaatgc tgtttacgtc tttatgggag caggagacat ccaaacctat
    30901 gaatactcat ttgagcgtct cttgtctaac ttgacaagca atgttcaata ggatgttccc
    30961 atggaaattc caattaagat cattcaggca agcaagtctg atttgcctga gataggggca
    31021 cttcagacct cgtcttttcc agctgaaaag cagcaacttt cccatatttt agaagaaagt
    31081 atccgtaagt gtgcggatac ctttcttcta gctagggatg aaaatcaact tttaggctat
    31141 attttatcaa gtccccagtc agacaatccg caatatctaa aagtacattc tttagtcatc
    31201 gagtctgacc atcagagaca gggcttggga acacttcttc ttgcagcctt gaaagaggtg
    31261 gcagttgatc tggattacaa agggattcgt ttggagagtc ctgatgagct gctttcctat
    31321 tttgaaatga acggttttgt tgatgaagaa gcaactttgc tctatgcaac tagccagggc
    31381 tatagtatga tttggtttaa tcccttttat ctggaggaac aatgaaaatc agacaagcaa
    31441 gattagaaga tttggatcgg attgttgaac ttgaatttga aaatttttcg gtcgaagaag
    31501 ccattcctcc ttctgtcttt gaagcacatt tgagagaaat tcagacctct tttctggttg
    31561 ctgaaaaaga aggaagaatc atgggttata tcgaaggacc agttggcctg caccgccatc
    31621 tgcaagacca gtcttttaca gaagaaataa aagactatag tcatgagcct ggtggttata
    31681 tctctgtgac ctgtctgtct attgccaagg aggcacaggg actcggactg ggtcagaaat
    31741 tgctgacagc tttgaaagaa gttgctcttg aagatgagag agatggcatt aatctaacct
    31801 gtcatgacta tctcatcgcc tattatgaaa aacatggatt tgtcaacgaa ggccagtccc
    31861 agtcaacctt tgcaggggaa acatggtatg atatggtctg ggaaatgaaa aaataagtta
    31921 ggaaaagtat catagattgc tttttttgga cttttaagat ataatattat ggattatcaa
    31981 caaggaggaa aaacttttga gtgaaaagtc aagagaagaa gagaaattaa gctttaaaga
    32041 gcagattctg agagatttag aaaaagtaaa aggctatgat gaagttctga aagaagatga
    32101 ggcagtagtt cgcactcctg caaatgaacc ttcagctgaa gaactcatga ctgattcctt
    32161 gtcaacggta gaggagatta tgagaaaagc tcctaccgtg cctactcacc caagtcaagg
    32221 tgtaccagct tctccagcag atgagattca aagagaaact cctggtgttc caagtcatcc
    32281 aagtcaagat gtaccttctt ctccagcgga agaaagtgga tcaagaccag gtcctgttag
    32341 acctaagaaa cttgaaagag aatacaatga aaccccaaca agggtagctg tttcctatac
    32401 gacggcagag aaaaaagcag aacaagcagg tccagaaaca cctacgcctg ctacagaaac
    32461 agtggatatc atcagcgata catcacgtcg tagccgtaga gaaggagcaa aacccgttaa
    32521 tcctaagaaa gagaagaagt cacatgtgaa agcttttgtg atttcattcc ttgtattcct
    32581 tgccttgctc tcagcaggtg gttactttgg ttaccagtac gtgctagatt ctttgttacc
    32641 tatcgatgct aattctaaga aatatgtgac ggttggaatt ccagaaggtt caaacgttca
    32701 agaaatcggt acgacgcttg aaaaagctgg tttggtaaag catggtctga tttttagttt
    32761 ttatgccaag tataaaaatt ataccgactt gaaagcaggt tactacaatt tgcaaaagag
    32821 tatgagtaca gaagacttac tcaaagagtt gcaaaaaggt ggaacagatg aaccgcaaga
    32881 acctgtactt gcgactttga caattccaga aggttatacc ttggatcaga ttgctcaagc
    32941 tgtgggtcaa ttgcaaggtg acttcaaaga gtctttgaca gcggaggctt tcttggctaa
    33001 agttcaagat gagacgttta tcagtcaagc agtagcgaaa tatcctactt tactggaaag
    33061 tttgcctgta aaagacagcg gtgcgcgtta tcgtttggaa ggataccttt tcccagctac
    33121 atactctatc aaggaaagca caactattga gagcttgatt gatgagatgt tagctgctat
    33181 ggataagaac ctatctcctt actatagtac tatcaaatct aaaaatttga ctgtcaatga
    33241 gttgttgacc attgcttcct tggtcgaaaa agaaggtgcc aagacagaag atcgtaagct
    33301 cattgcaggt gtattctaca atcgtttaaa tcgtgatatg ccacttcaaa gtaatattgc
    33361 aatcttgtat gcccaaggaa aactggggca aaatatcagt ctagctgagg atgttgcgat
    33421 tgataccaac attgattcac cttataatgt ttataaaaat gtaggtctca tgcctggtcc
    33481 agtcgatagt ccaagtctgg atgcgattga gtcaagcatc aatcaaacta agagcgataa
    33541 cctctacttt gtagcagatg tcacagaagg caaggtctac tatgctaaca atcaagaaga
    33601 ccacgaccgc aatgtcgctg aacatgtcaa cagcaaatta aactaaacaa actaaaatta
    33661 tgtgatacgt cacataattt tctttagaaa atattatcag aagaaagttg agaaaaatgg
    33721 cagaaaaaac atatcctatg acccttgagg aaaaggaaaa acttgaaaaa gaattagaag
    33781 aattgaaatt ggttcgtcga ccagaagtgg tagaacgcat taagattgcc cgttcatacg
    33841 gtgacctttc agaaaacagt gagtacgaag cagctaagga tgaacaagcc tttgtcgaag
    33901 gacaaatctc tagcttagaa acaaaaatcc gctatgctga aatcgtcaat agcgacgcag
    33961 ttgcccagga cgaagtagcg attggtaaaa cagtcaccat ccaagaaatt ggtgaggacg
    34021 aagaagaagt ttatattatc gtaggttcag ctggtgcgga tgcctttgca ggtaaggttt
    34081 caaatgaaag cccaattggg caggccttga ttggcaagaa aacaggtgac acagcaacca
    34141 ttgaaacgcc tgttggtagc tatgatgtaa aaatcttgaa ggttgaaaaa acagcctaaa
    34201 aacagaaaaa ggagtgggga ggcgatgtgc ttcactcact cctttttcca ttttgctatt
    34261 cttcgaaaat ctcttcaaac cacgtcagcg tcgccttgcc gtatgtatgg ttactgactt
    34321 tgtcagtttc atctacaacc tcaaaac
//
LOCUS       DAVBBO010000018        33324 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ST1
            SAMEA2066453-rid20184263.denovo.018, whole genome shotgun sequence.
ACCESSION   DAVBBO010000018 DAVBBO010000000
VERSION     DAVBBO010000018.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2066453
            Sequence Read Archive: ERR351777
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 33324)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 33324)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980402.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980402.1
            Genome Coverage       :: 176x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:17:33
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,141
            CDSs (total)                      :: 2,104
            Genes (coding)                    :: 1,953
            CDSs (with protein)               :: 1,953
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 16S)
            partial rRNAs                     :: 1 (23S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 151
            CDSs (without protein)            :: 151
            Pseudo Genes (ambiguous residues) :: 0 of 151
            Pseudo Genes (frameshifted)       :: 73 of 151
            Pseudo Genes (incomplete)         :: 76 of 151
            Pseudo Genes (internal stop)      :: 40 of 151
            Pseudo Genes (multiple problems)  :: 32 of 151
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..33324
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2066453-rid20184263.denovo.018"
                     /strain="ST1"
                     /db_xref="taxon:1313"
     gene            <1..327
                     /locus_tag="VQU30_000862"
     CDS             <1..327
                     /locus_tag="VQU30_000862"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000700388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine motif-containing protein"
                     /protein_id="HET2446996.1"
                     /translation="KPQTEKPEEETPREEKPQSEKPESPKPTEEPEEESPEESEEPQV
                     ETEKVEEKMREAEDLLGKIQDPIIKSNAKETLTGLKNNLLFGTQDNNTIMAEAEKLLA
                     LLKESK"
     gene            749..979
                     /locus_tag="VQU30_000863"
     CDS             749..979
                     /locus_tag="VQU30_000863"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863127.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIA"
                     /protein_id="HET2446997.1"
                     /translation="MESIGIGLVIVSHSKHIAEGVVELISKVAKDVPITYVGGTEGGG
                     IGTSFDQVDRVVSENPADTLLAFFDLGSAIKC"
     gene            1383..2096
                     /locus_tag="VQU30_000864"
     CDS             1383..2096
                     /locus_tag="VQU30_000864"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000499426.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YjjG family noncanonical pyrimidine
                     nucleotidase"
                     /protein_id="HET2446998.1"
                     /translation="MFYKFLLFDLDHTLLDFDAAEDVALTQLLKEEGVADIQAYKDYY
                     VPMNKALWKDLELKKISKQELVNTRFSRLFAHFGQEKDGSFLAQRYQFYLAQQGQTLS
                     GAHDLLDSLIERDYNLYAATNGITAIQTGRLAQSGLAPYFNQVFISEQLQTQKPDALF
                     YEKIGQQIAGFSKEKTLMIGDSLTADIQGGNNAGIDTIWYNPHHLENHTQAQPTYEVY
                     SYQDLLDCLDKNILEKITF"
     gene            2154..2756
                     /locus_tag="VQU30_000865"
     CDS             2154..2756
                     /locus_tag="VQU30_000865"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001810555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2446999.1"
                     /translation="MSEVDFNEAVNYEFTSDTCQLANSIYQSLFKFFDKKNFSGDLIF
                     TWKSPSLVKEGDYIGRRDSQVDNLRVIGNIFPNYLTNRKYSLNMNRNGCMGDFPHDFF
                     DIYLDHVAKYAYEQKVNNIKEYYPLKRAILHQENALYFRFFSNFDDFLEKNYLKTIWQ
                     VSKETPFSEMDFNMFKNISEKIIFERGSKMLNDLKSNYKK"
     gene            2892..3545
                     /locus_tag="VQU30_000866"
     CDS             2892..3545
                     /locus_tag="VQU30_000866"
                     /EC_number="3.2.2.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001841111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil-DNA glycosylase"
                     /protein_id="HET2447000.1"
                     /translation="MEHSSWHALIKAQLPEGYFGKINQFMEQVYSQGIIYPPKEKVFQ
                     ALLTTLLEEVKVVILGQDPYHGPGQAQGLSFSVPDSIPAPPSLQNILKELSDDIGVKK
                     SHDLTAWAEQGVLLLNACLTVPAGQANGHAGQIWEPFTDAVIQVVNHLDRPVVFVLWG
                     AYARKKKALVTNPHHLIIESAHPSPLSVYRGFWGSKPFSKANAFLKETGQEPIDWLR"
     gene            3555..4019
                     /locus_tag="VQU30_000867"
     CDS             3555..4019
                     /locus_tag="VQU30_000867"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003012002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="8-oxo-dGTP diphosphatase"
                     /protein_id="HET2447001.1"
                     /translation="MPQLATICYIDNGKELLMLHRNKKPNDVHEGKWIGVGGKLERGE
                     TPQECAAREILEETGLKAKPVLKGVITFPEFTPDLDWYTYVFKVTEFEGDLIDCNEGT
                     LEWVPYDEVLSKPTWEGDHTFVEWLLEDKPFFSAKFVYDGDKLLDTQVDFYE"
     gene            4032..5300
                     /locus_tag="VQU30_000868"
     CDS             4032..5300
                     /locus_tag="VQU30_000868"
                     /EC_number="3.5.2.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000924471.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotase"
                     /protein_id="HET2447002.1"
                     /translation="MLLIKNGRVMDPKSGLDQVCDVLVQDGKIIKIAPEITEEGAETI
                     DATGLVVAPGLVDIHVHFREPGQTHKEDIHTGALAAAAGGFTTVVMMANTSPTISDVE
                     TLQAVLQSAAKEKINVKTVATITKNFNGKNLTDFKALLEAGAVGFSDDGIPLESSKIV
                     KEAMEEAKKLNTFISLHEEDPGLNGVLGFNENIAREHFHICGATGVAEYAMMARDVMI
                     AYATKAHVHIQHLSKEESVKVVEFAQGLGAEVTAEVAPQHFSKTEALLLTQGSNAKMN
                     PPLRLESDRRAVIEGLKSGVITVIATDHAPHHVDEKNVEDITKAPSGMTGLETSLSLG
                     LTYLVEAGELSLMELLEKMTYNPAKLYNFEAGYLAENGPADITIFDAKADRLVDSHFA
                     SKAANSPFIGETLKGQVKYTICKGQIVYQA"
     gene            5314..5574
                     /locus_tag="VQU30_000869"
     CDS             5314..5574
                     /locus_tag="VQU30_000869"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2447003.1"
                     /translation="MNYFRKRRERQAKSNSGIYCPAANRSKIQYETKEKADHAVQYDN
                     GGLVRSYYCRTCACWHTTSKSNKPPLSLKNYGLKLFGLDKSE"
     gene            5585..6946
                     /gene="pdrM"
                     /locus_tag="VQU30_000870"
     CDS             5585..6946
                     /gene="pdrM"
                     /locus_tag="VQU30_000870"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000278532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sodium-coupled multidrug efflux MATE transporter
                     PdrM"
                     /protein_id="HET2447004.1"
                     /translation="MYKTKCLREKLVLFLKIFFPILIYQFANYSASFVDTAMTGQYNT
                     MDLAGVSMATSIWNPFFTFLTGIVSALVPIIGHHLGRGKKEEVASDFYQFIYLALGLS
                     VVLLGMVLFLAPTILNHIGLEAAVAAVAVRYLWFLSIGIIPLLLFSVIRSLLDSLGLT
                     KLSMYLMLLLLPLNSGFNYLLIYGAFGVPELGGAGAGLGTSLAYWVLLGISVLVLFKQ
                     EKLKALHLEKRIPLNMDKIKEGVRLGLPIGGTVFAEVAIFSVVGLIMAKFSSLIIASH
                     QSAMNFSSLMYAFPMSISSAMAIVVSYEVGAKRFDDAKTYIGLGRWTALIFAAFTLTF
                     LYIFRGNVASLYGNDPKFIDLTARFLTYSLFFQLADTFAAPLQGILRGYKDTVIPFYL
                     GLLGYWGVAIPVATLFDSLTDFGAYSYWIGLIISLIVSGALYRWRLTVIMKRFESLAK
                     SKR"
     gene            7100..8068
                     /locus_tag="VQU30_000871"
     CDS             7100..8068
                     /locus_tag="VQU30_000871"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844850.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine pyrophosphate-dependent dehydrogenase
                     E1 component subunit alpha"
                     /protein_id="HET2447005.1"
                     /translation="MSTLDKNLLLEMFRKMEEIRRMDLKIAQLVKKGKVPGMTHFSVG
                     EEAANVGAMLALNPDDLITSNHRGHGQAIAKGIDLNGMMAEILGKYTGTCKGKGGSMH
                     IADLDAGNLGANGIVGGGMGIAVGAALSQQMQNTGKIVVCFFGDGATNEGVFHEAVNM
                     ASIWNLPVIFYCINNGYGISADIKKMTNIEHIHQRSAAYGIPGMFIEDGNNVIDVYEG
                     FQKAVDHVRSGNGPVLIESVTYRWLGHSSSDPGKYRTREEVELWKQKDPIENLRNYLI
                     ENNIASAEELEEIQAQVKEAVEASVKFAEESPFPPLESAFEDIYAD"
     gene            8084..9076
                     /locus_tag="VQU30_000872"
     CDS             8084..9076
                     /locus_tag="VQU30_000872"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000448722.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-ketoacid dehydrogenase subunit beta"
                     /protein_id="HET2447006.1"
                     /translation="METKTMSFRDTIILAMSEEMRRDENVFLMGEDVGVFGGDFGTSV
                     GMLEEFGPERVRDCPISEAAISGAAAGAAMTGLRPIVDMTFMDFSVIAMDNIVNQAAK
                     TRYMFGGKGQVPMTVRCAAGNGVGSAAQHSQSLESWFTHIPGLKVVAPGTPADMKGLL
                     KSSIRDKNPVIILEYKSEFNQKGEVPVDPDYTIPLGVGEIKRQGTDVTVVTYGKMLRR
                     VVQAAEELAEEGISVEIVDPRTLVPLDKDIIINSVKKTGKVVLVNDAHKTSGYISEIS
                     AIISESEAFDYLDAPIRRCAGEDVPMPYAQNLENAMIPTVESIKDAIRKTYNKE"
     gene            9294..10337
                     /locus_tag="VQU30_000873"
     CDS             9294..10337
                     /locus_tag="VQU30_000873"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008808675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrolipoamide acetyltransferase"
                     /protein_id="HET2447007.1"
                     /translation="MADDKLRATPAARKLADDLGINLYDVSGSGANGRVHKEDVETYK
                     DTNVVRISPLAKRIALEHNIAWQEIQGTGHRGKIMKKDVLALLPENIENDSIKSPAQI
                     EKVEEVPDNVTPYGEIERIPMTPMRKVIAQRMVESYLTAPTFTLNYEVDMTEMLALRK
                     KVLEPIMEATGKKTTVTDLLSLAVVKTLMKHPYINASLTEDGKTIITHNYVNLAMAVG
                     MDNGLMTPVVYNAEKMSLSELVVAFKDVIGRTLDGKLAPSELQNSTFTISNLGMFGVQ
                     SFGPIINQPNSAILGVSSTIEKPVVVNGEIVIRPIMSLGLTIDHRVVDGMAGAKFMKD
                     LKELIETPISMLI"
     gene            10401..12086
                     /gene="lpdA"
                     /locus_tag="VQU30_000874"
     CDS             10401..12086
                     /gene="lpdA"
                     /locus_tag="VQU30_000874"
                     /EC_number="1.8.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014931946.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrolipoyl dehydrogenase"
                     /protein_id="HET2447008.1"
                     /translation="MPKAGVDMTEGQIVQWNKKVGEFVKEGEILLEIMTDKVSMELEA
                     EEDGYLIAILKGDGETVPVTEIIGYLGEERENIPTAGAASPEASPVPVASTSNDDGKS
                     DDAFDIVVIGGGPAGYVAAIKAAQLGGKVALVEKSELGGTCLNRGCIPTKTYLHNAEI
                     IENIGHAANRGIVIENPNFTVDMEKLLETKSKVVNTLVGGVAGLLRSYGVTVHKGIGT
                     ITKDKNVLVNGSELLETKKIILAGGSKVSKINVPGMQSPLVMTSDDILEMNEVPESLV
                     IIGGGVVGIELGQAFMTFGSKVTVIEMMDRIVPAMDAEVSKNLRLILERKGMTILTGT
                     KLQEIIEENGQLRIKVEGKDDIIASKALLSIGRMPDLEGIGEVEFELDRGCIKVNEYM
                     ETSVPGIYAPGDINGTKMLAHAAFRMGEVSAENALKGNHAVAKLNLTPAAIYTLPEVA
                     AVGLTEEQAREKYDVAIGKFNFAANGRAIASDAAQGFVKVIADKKYGEIIGVHIIGPA
                     AAELINEASSIIEMEITVEEMLKTIHGHPTYSEVMYEAFADVLGMAIHSPKKK"
     gene            12150..13139
                     /locus_tag="VQU30_000875"
     CDS             12150..13139
                     /locus_tag="VQU30_000875"
                     /EC_number="6.3.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000873976.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoate--protein ligase"
                     /protein_id="HET2447009.1"
                     /translation="MKYIINHSNDTAFNIALEEYAFKHLLDEDQIFLLWINKPSIIVG
                     RHQNTIEEINRDYVRENGIEVVRRISGGGAVYHDLNNLNYTIISKEDENKAFDFKSFS
                     TPVINTLAQLGVKAEFTGRNDLEIDGKKFCGNAQAYINGRIMHHGCLLFDVDLSVLAN
                     ALKVSKDKFESKGVKSVRARVTNIINELPKKITVEKFRDLLLEYMKKEYPEMTEYVFS
                     EEELAEINHIKDTKFGTWDWNYGKSPEFNVRRGTKFTSGKVEVFANVTESKIQDIKIY
                     GDFFGIEDVAAVEDVLRGVKYEREDVLKALKTIDITRYFAGISREEIAEAVVG"
     gene            complement(13206..14276)
                     /gene="xerS"
                     /locus_tag="VQU30_000876"
     CDS             complement(13206..14276)
                     /gene="xerS"
                     /locus_tag="VQU30_000876"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000817875.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine recombinase XerS"
                     /protein_id="HET2447010.1"
                     /translation="MKREILLERIDKLKQLMPWYVLEYYQSKLAVPYSFTTLYEYLKE
                     YDRFFSWVLESGISNADKISDIPLSVLENMSKKDMESFILYLRERPLLNANTTKQGVS
                     QTTINRTLSALSSLYKYLTEEVENDQGEPYFYRNVMKKVSTKKKKETLAARAENIKQK
                     LFLGDETEGFLTYIDQEHPQQLSNRALSSFNKNKERDLAIIALLLASGVRLSEAVNLD
                     LRDLNLKMMVIDVTRKGGKRDSVNVAAFAKPYLENYLAIRNQRYKTEKTDTALFLTLY
                     RGVPNRIDASSVEKMVAKYSEDFKVRVTPHKLRHTLATRLYDATKSQVLVSHQLGHAS
                     TQVTDLYTHIVNDEQKNALDSL"
     gene            complement(14860..16410)
                     /locus_tag="VQU30_000877"
     CDS             complement(14860..16410)
                     /locus_tag="VQU30_000877"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000392528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chloride channel protein"
                     /protein_id="HET2447011.1"
                     /translation="MEEQSEIVRSKKEFAFASSTILSQVGRGIIVGLIVGIIVGSFRF
                     LIEKGFHLIQGVYQDQGYLVRNLFVLVLFYILICWLSAKLTRSEKDIKGSGIPQVEAE
                     LKGLMSLNWWGILWKKYVLGILAIASGLMLGREGPSIQLGAVGGKGIAKWLKSSPVEE
                     RSLIASGAAAGLAAAFNAPIAALLFVVEEVYHHFSRFFWVSTLAASIVANFVSLLMFG
                     LTPVLDMPDNIPPMTLDQYWIYLVMGIFLGFSGFLYEKAVLNVGRVYDLIGQKIHLDR
                     AYYPILAFIIIIPVGIFLPQIIGGGNQLVLSLTEQNFSFQVLLAYFLIRFIWSMISYG
                     SGLPGGIFLPILALGSLLGSLVGVICVNLGLVSQEQFPIFVILGMSGYFGAISKAPLT
                     AMILVTEMVGDIRNLMPLGLVTLVSYIIMDLLKGTPVYEAMLEKMLPEEVSSEGEVTL
                     IEIPVSDKIAGKQVHELNLPHNVLITTQVHNGKSQTVNGSTRMYLGDMIHLVIPKSEI
                     GKVKDLLL"
     gene            complement(16426..17205)
                     /locus_tag="VQU30_000878"
     CDS             complement(16426..17205)
                     /locus_tag="VQU30_000878"
                     /EC_number="3.1.26.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000201102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease HII"
                     /protein_id="HET2447012.1"
                     /translation="MATIKEIKELLVTVKELESPIFLDLEKDNRSGVQKEISKHKRAI
                     QAELDENLRLESMLSYEKELYKQGLTLIAGIDEVGRGPLAGPVVAAAVILPKNCKIKG
                     LNDSKKIPKKKHLEIFQVVQDQALSIGIGIIDNQVIDQVNIYEATKLAMQEAISQLSP
                     QPEHLLIDAMKLDLPISQTSIIKGDANSLSIAAASIVAKVTRDELMKEYDQQFPGYDF
                     ATNAGYGTAKHLEGLTKLGVTPIHRTSFEPVKSLVLGKKES"
     gene            complement(17192..18043)
                     /gene="ylqF"
                     /locus_tag="VQU30_000879"
     CDS             complement(17192..18043)
                     /gene="ylqF"
                     /locus_tag="VQU30_000879"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000201313.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTPase YlqF"
                     /protein_id="HET2447013.1"
                     /translation="MATIQWFPGHMSKARRQVQENLKFVDFVTILVDARLPLSSQNPM
                     LTKIVGDKPKLLILNKADLADPAMTKEWRQYFESQGIQTLAINSKEQVTVKVVTDAAK
                     KLMADKIARQKERGIQIETLRTMIIGIPNAGKSTLMNRLAGKKIAVVGNKPGVTKGQQ
                     WLKTNKDLEILDTPGILWPKFEDETVALKLALTGAIKDQLLPMDEVTIFGINYFKEHY
                     PEKLAERFKQMKIEEEAPVIIMDMTRALGFRDDYDRFYSLFVKEVRDGKLGNYTLDTL
                     EGLDGND"
     gene            complement(18250..18426)
                     /locus_tag="VQU30_000880"
     CDS             complement(18250..18426)
                     /locus_tag="VQU30_000880"
                     /inference="COORDINATES: protein motif:HMM:NF012948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HET2447014.1"
                     /translation="MQAGIPTDNEVSYALIYQQETLPATGSSTSALTALGLLAVGSLV
                     LLVHNMTGTVFCSL"
     gene            complement(18478..24369)
                     /gene="iga"
                     /locus_tag="VQU30_000881"
     CDS             complement(18478..24369)
                     /gene="iga"
                     /locus_tag="VQU30_000881"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000417171.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="immunoglobulin A1 protease"
                     /protein_id="HET2447015.1"
                     /translation="MEKYFGEKQERFSFRKLSVGLVSATISSLFFMSVLASSSVDAQE
                     TAGVHYKYVADSELSSEEKKQLVYDIPTYVENDDETYYLVYKLNSQNQLAELPNTGSK
                     NERQALVAGASLAALGILIFAVSKKKVKNKTVLHLVLVAGMGNGVLVSVHALENHLLL
                     NYNTDYELTSGEKLPLPKEISGYTYIGYIKEGKTTSDFEVSNQEKSAATPTKQQKVDY
                     NVTPNFVDHPSTVQAIQEQTPVSSTKPTEVQVVEKPFSTELINPRKEEKQSSDSQEQL
                     AEHKNLETKKEEKISPKEKTGVNTLNPQDEVLSGQLNKPELLYREETIETKIDFQEEI
                     QENPDLAEGTVRVKQEGKLGKKVEIVRIFSVNKEEVSREIVSTSTTAPSPRIVEKGTK
                     KTQVIKEQPETGVEHKDVQSGSIVEPAIQPELPEAVVSDKGEPEVQPTLPEAVVTDKG
                     ETEVQPESPDTVVSDKGEPEQVAPLPEYKGNIEQVKPETPVEKTKEQGPEKTEEVPVK
                     PTEETPVNPNEGTTEGTSIQEAENPVQPAEESTTNSEKVSPDTSSENTGEVSSNPSDS
                     TTSVGESNKPEHNDSKNENSEKTVEEVPVNPNEGTVEGTSNQETEKPVQPAEETQTNS
                     GKIANENTGEVSNKPSDSKPPVEESNQPEKNGTATKPENSGNTTSENGQTEPEKKLEL
                     RNVSDIELYSQTNGTYRQHVSLDGIPENTDTYFVKVKSSAFKDVYIPVASITEEKRNG
                     QSVYKITAKAEKLQQELENKYVDNFTFYLDKKAKEENTNFTSFSNLVKAINQNPSGTY
                     HLAASLNANEVELGPDERSYIKDTFTGRLIGEKDGKNYAIYNLKKPLFENLSGATVEK
                     LSLKNVAISGKNDIGSLANEATNGTKIKQVHVDGVLAGERGVGGLLAKADQSSIAESS
                     FKGRIVNTYETTDAYNIGGLVGHLTGKNASIAKSKATVTISSNTNRSDQTVGGLAGLV
                     DQDAHIQNSYAEGDINNVKHFGKVAGVAGYLWDRTSGEEKHAGELTNVLSDVNVTNGN
                     AITGYHYTGMKVANTFSSKANRVFNVTLEKDEVVSKESFEERGTMLDASQIVSKKAEI
                     NPLTLPTVEPLSTSGKKDSDFSKIAHYQANRALVYKNIEKLLPFYNKSTIVKYGNLVK
                     ENSLLYQKELLSAVMMKDDQVITDIVSNKQTANKLLLHYNDHSSEKFDLKYQTDFANL
                     AEYNLGNTGLLYTPNQFLYDRDSIVKEVLPELQKLDYQSDAIRKTLGISPEVKLTELY
                     LEDQFSKTKQNLGDSLKKLLSADAGLASDNSVTRGYLVDKIKNNKEALLLGLTYLERW
                     YNFNYGQVNVKDLVMYHPDFFGKGNTSPLDTLIELGKSGFNNLLAKNNVDTYGISLAS
                     QHGTTDLFSTLEHYRKVFLPNTSNNDWFKSETKAYIVEEKSTIEEVKTKQGLAGTKYS
                     IGVYDRITSATWKYRNMVLPLLTLPERSVFVISTMSSLGFGAYDRYRSSDHKAGKALN
                     DFVEENARETAKRQRDHYDYWYRILDEQSREKLYRTILLYDAYKFGDDTTSGKATAEA
                     KFDSSNPAMKNFFGPVGNKVVHNQHGAYATGDGVYYMSYRMLDKDGAITYTHEMTHDS
                     DQDIYLGGYGRRNGLGPEFFAKGLLQAPDQPSDATITINSILKHSKSDSTEGSRLQVL
                     DPTERFQNAADLQNYVHNMFDLIYMMEYLEGQSIVNKLSVYQKMAALRKIENKYVKDP
                     ADGNEVYATNVVKELTEAEARNLNSFESLIDHNILSAREYQSGDYERNGYYTIKLFAP
                     IYSALSSEKGTPGDLMGRRIAYELLAAKGFKDGMVPYISNQYEEDAKQQGQTINLYGK
                     ERGLVTDELVLKKVFDGKYKTWAEFKTAMYQERVDQFGNLKQVTFKDPTKPWPSYGTK
                     TINNVDELQALMDQAVLKDAEGPRWSNYDPEIDSAVHKLKRAIFKAYLDQTNDFRSSI
                     FENKK"
     gene            complement(24578..25756)
                     /locus_tag="VQU30_000882"
     CDS             complement(24578..25756)
                     /locus_tag="VQU30_000882"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2447016.1"
                     /translation="MTLPVRKSLHDAVLQASKADTWEQATKEWNEVSLIFNGIGRSNC
                     VCRNAIKYAYELFNGVTGQRLFPIGSDCVRHFHRLPLDQQLEEEEKLLRKVENLTRKA
                     QKKEKIKVNKSDFDERLLKWLWEKGVFKPNRGNQFAPERDYQLFLEVFQGGSWTKAEP
                     KKKARMEEVLEKCIKPFLLGKSDDQLYLVKLGKEKIDYEQELRIQAEKERKKRDKIAK
                     QYADNLVLAMGPAERAYQDYFGFTETLTQEERKWEKILFGKNRAERAIKAKQYQKELE
                     KDQRIASQDPIERKQKQTWILNSYFRELPEEKARFSRLLLEYRKSGEVPFSTEYLSDH
                     LIDFFYKMKAFEFEIAPEQVRDFLKKSLQEDHRSSAQGSWIEGILLNCLKPFLERLVI
                     "
     gene            complement(25926..29576)
                     /gene="addA"
                     /locus_tag="VQU30_000883"
     CDS             complement(25926..29576)
                     /gene="addA"
                     /locus_tag="VQU30_000883"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000767270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helicase-exonuclease AddAB subunit AddA"
                     /protein_id="HET2447017.1"
                     /translation="MKLIPFLSEEEIQKLQEAEANSSKEQKKTAEQIEAIYTSGQNIL
                     VSASAGSGKTFVMAERILDQLARGVEISQLFISTFTVKAATELKERLEKKISKKIQET
                     DDVDLKQHLGRQLADLPNAAIGTMDSFTQKFLGKHGYLLDIAPNFRILQNQSEQLLLE
                     NEVFHEVFEAHYQGKQKETFSHLLKNFAGRGKDERGLRQQVYKIYDFLQSTSNPQKWL
                     SESFLKGFEKADFTSEKEKLTEQIKQALWDLESFFRYHLDNDAKEFAKAAYLENVQLI
                     LDEICSLNQESDSQAYQAVLARVVAISKEKNGRALTNASRKADLKPLADAYNEERKTQ
                     FAKLGQLSDQITILDYQERYHQDTWKLAKTFQTFMSHFVEAYRQRKRQENAFEFADIS
                     HYTIEILENFPQVRESYQERFHEVMVDEYQDTNHIQERMLELLSNGHNRFMVGDIKQS
                     IYRFRQADPQIFNEKFQRYAQNPQEGKLILLKENFRSSSEVLSATNDVFERLMDQEVG
                     EINYDNKHQLVFANTKLTPNPDNKAEFLLYDKDDTGEEEESQTETKLTGEMRLVIKEI
                     LKLHQEKGVAFKEIALLTSSRSRNDQILLALSEYGIPVKTDGEQNNYLQSLEVQVMLD
                     TLRVIHNPLQDYALVALMKSPMFGFDEDELARLSLQKAEDKVHENLYEKLVNAQKMAS
                     SQKGLIHTALVEKLKQFMDILASWRLYAKTHSLYDLIWKIYNDRFYYDYVGALPNGPA
                     RQANLYALALRADQFEKSNFKGLSRFIRMIDQVLEAQHDLASVAVAPPKDAVELMTIH
                     KSKGLEFPYVFILNMDQNFNKQDSMSEVILSRQNGLGVKYIAKMETGAVEDHYPKTIK
                     LSIPSLTYRQNEEELQLASYSEQMRLLYVAMTRAEKKLYLVGKGSREKLESKEYPAAK
                     NGKLNSNTRLQARNFQDWLWAISKVFTKDKLNFSYRFIDEDQLTREAIGELETKSPLQ
                     DSSQADNRQSDTIKEALEMLKEVEVYNTLHRAAIELPSVQTPSQIKKFYEPVMDMEGV
                     EIAGQGQSVGKKISFDLPDFSTKEKVTGAEIGSATHELMQIIDLSQQLTLASLTETLK
                     QVQTSQAVRDKINLDKILAFFDTALGQEILANTDHLYREQPFSMLKRDQKSQEDFVVR
                     GILDGYLLYENKIVLFDYKTDRYDEPSQLVDRYRGQLALYEEALSRAYSIENIEKYLI
                     LLGKDEVQVVKV"
     gene            complement(29573..32848)
                     /gene="rexB"
                     /locus_tag="VQU30_000884"
     CDS             complement(29573..32848)
                     /gene="rexB"
                     /locus_tag="VQU30_000884"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002206154.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent nuclease subunit B"
                     /protein_id="HET2447018.1"
                     /translation="MKLLYTDIRTSLTEILTREAEELVAAGKRVFYIAPNSLSFEKER
                     AVLECLSQQASFSITVTRFAQMARYLVLNDLPVKTTLDDIGLGLAFYKCLAELDPKDL
                     RVYGAIKQDPQLIQQLIELYHEMTKSQMSFLDLENLTDEDKRADLLLIFEKVTAYLNQ
                     GQLAQGSQLSHLIEAIENDKVSSDFNQITLVIDGFTRFSAEEERVVDLLHGKGVEIVI
                     GAYASKKAYTSPFSEGNLYQASVKFLHHLASKYQTPAQDCSQTHEKMDSFDKASRLLE
                     SSYDFSELALDVDEKDRENLQIWSCLTQKEELELVARSIRQKLHENSDLSYKHFRILL
                     GDVASYQLSLKTIFDQYQIPFYLGRSEAMAHHPLTQFVESILALKRYRFRQEDLINLL
                     RTDLYTDLSQSDIDAFEQYIRYLGINGLPAFQQTFTKSHHGKFNLERLNVLRLRILAP
                     LETLFASRKQKAENLLQKWSVFLKEGAVTKQLQDLTTTLEAVEQERQAEVWKAFCHVL
                     EQFATVFAGSQVSLEDFLALLHSGMSLSQYRTIPATVDTVLVQSYDLIAPLTADFVYA
                     IGLTQDNLPKISQNTSLLTDEERQNLNQTTEEGVQLLIASSENLKKNRYTMLSLVNSA
                     RKQLFLSAPSLFNESESKESAYLQELIHFGFRRREKRMNHKGLSKEDMGSYHSLLSSL
                     VAYHQQGEMSDTEQDLTFVKVLSRVIGKKLDQQGLENPAIPISPSSKTLAKDTLQALY
                     PAKQEFYLSTSGLTEFYRNEYSYFLRYVLGLQEELRLRPDARSHGNFLHRIFERALQL
                     PNEDSFDQRLEQAIQETSQEREFEAIYQESLEAQFTKEVLLDVARTTGHILRHNPAIE
                     TIKEEANFGGKDQAFIQLDNGRSVFVRGKVDRIDRLKANGAIGVVDYKSSLTQFQFPH
                     FFNGLNSQLPTYLAALKREGEQNFFGAMYLEMAEPVQSLMAVKSLAGAVVEASKSMKY
                     QGLFLEKESSYLGEFYNKNKANQLTDEEFQLLLDYNAYLYKKAAEKILAGRFAINPYT
                     ENGRSIAPYVQQHQAITGFEANYHLGQARFLEKLDLADGKRLVGEKLKQAWLEKIREE
                     LNR"
     gene            complement(33048..33203)
                     /locus_tag="VQU30_000885"
                     /pseudo
     CDS             complement(33048..33203)
                     /locus_tag="VQU30_000885"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000710121.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase family lipid kinase"
BASE COUNT         9515 a         6538 c         6861 g        10410 t
ORIGIN      
        1 aaacctcaga cagaaaaacc tgaggaagaa acccctcgag aagagaaacc gcaaagcgag
       61 aaaccagagt ctccaaaacc aacagaggaa ccagaagaag aatcaccaga ggaatcagaa
      121 gaacctcagg tcgagactga aaaggttgaa gaaaaaatga gagaggctga agatttactt
      181 ggaaaaatcc aggatccaat tatcaagtcc aatgccaaag agactctcac aggattaaaa
      241 aataatttac tatttggcac ccaggacaac aatactatta tggcagaagc tgaaaaacta
      301 ttggctttat taaaggagag taagtaaagg tagcagcatt ttctaactcc taaaaacagg
      361 ataggagaac gggaaaacga aaaatgagag cagaatgtga gttctagttc tcattttttt
      421 catgaaaatg tgcaaaatat agtagattga aactagaata gtatacctct acttctaaaa
      481 cattgttaga aatcgatttg actgtcctgt tcttatttca ttttactata tcttaacaga
      541 tagtgtaaat aaagataaac tatttactgg ctaattaatc agttaaacac tagttaagga
      601 gtaatgatga aaaaaagaac aatactatta ttgatggcca gtctgttagc tcttgtctta
      661 ggagcatgtg gtttcttgga catattgatc ctggatcatt ctcatcagga ttactcttta
      721 ctgctatttt agaaactggg gtggtttgat ggaaagtatt ggtattggtc ttgttatcgt
      781 ttcacattcc aaacacattg cagaaggtgt tgttgaactg attagtaaag tagctaaaga
      841 tgttccgatt acttatgtag gaggaaccga gggcggagga attggaacga gttttgatca
      901 agtagatagg gttgtttccg aaaatccagc agatacttta cttgcctttt ttgacctagg
      961 ttctgctata aaatgttaag taaatgattt caaaatcaga aagggattgc tttgggcagt
     1021 tcctttttaa tgtaaatgta aaaggagtag aatcatagtg tttctaaatt gtgaatcaat
     1081 caaaactgat tgtgatgggg ctattctagc tttagaatcc ttcaaaaatt aaaatttaag
     1141 gcaatcaatt acttggaaga gtatgaaagc atttagttta taggaattct aggcctagaa
     1201 ttacatatgt atttatgaag ataggggtgt tcgatagtta gtattgttct gttctgaaag
     1261 atttgagctg tcagttgtat agaaagtgtt cgaatttttt ttaagtgatt aaattagtta
     1321 attgtatgag gttctttatg atataatgtt cttaatgaat tttcagaaag gaaaacctca
     1381 aattgttcta caaatttcta ctcttcgacc tcgaccacac tcttcttgat tttgatgctg
     1441 ctgaggatgt ggctttgacc caacttctaa aagaagaagg agttgcggat attcaggctt
     1501 ataaagatta ttacgttcct atgaacaagg ctctctggaa agacttggag ctgaagaaaa
     1561 tcagtaaaca agagctggtt aacacgcgct tttctcgttt atttgctcat tttggacagg
     1621 aaaaagacgg tagttttctt gcccagcgtt accaatttta cctcgcccag cagggacaaa
     1681 cactatcggg cgctcatgat ctcttggaca gcctcattga gcgtgattat aacttgtatg
     1741 ctgcgacaaa tggcattact gccattcaga caggacgttt ggctcaatct ggtctagcac
     1801 cttatttcaa tcaagtcttt atctcagaac agttgcaaac tcaaaagccg gatgctctct
     1861 tttatgaaaa gattggccag caaattgctg gatttagtaa agaaaagacg ctgatgattg
     1921 gagattctct aaccgccgac attcaaggtg gcaataatgc ggggattgat actatctggt
     1981 ataatcctca tcacctcgaa aatcacacac aagcccagcc gacttacgaa gtctattctt
     2041 accaagactt gctggattgt ttagataaaa atattcttga aaagatcaca ttttaaagga
     2101 gacgagctaa tgactacaaa aaagctaata ttactattga agagtacatt gaaatgtctg
     2161 aagttgattt taatgaagct gttaattatg aatttacatc tgacacttgt caattagcaa
     2221 atagtattta tcaatctctt tttaagtttt ttgataagaa aaatttctct ggcgatttaa
     2281 tttttacttg gaaatctcca tcattagtca aagaagggga ttatattggg agaagggatt
     2341 cacaagtaga taatcttaga gtaataggaa atatatttcc gaattatctt actaatcgaa
     2401 aatatagcct caatatgaat cgtaatggct gtatgggaga ttttcctcat gacttttttg
     2461 atatatacct agatcatgta gcaaaatatg cctacgaaca aaaagttaat aatattaaag
     2521 agtattatcc tttaaaaaga gcgattttac accaagagaa tgcattgtat tttcgatttt
     2581 tttctaattt tgacgacttt ttagaaaaaa attatttaaa gactatatgg caagtttcta
     2641 aagaaactcc tttttctgaa atggatttta atatgtttaa aaatatttca gaaaagataa
     2701 tcttcgaaag aggtagtaaa atgcttaatg atttaaaaag taattataaa aaatagccag
     2761 tctttataaa ctgtattcac gtattcaaat cgtatatagt cgatttatta aatctttaga
     2821 taaactgtaa aaagtggttt ccatagccac tttttgctat aatagaggca gtaaaaatga
     2881 aggagtcggc tatggaacac tcgtcttggc atgctttgat taaggcgcaa ttacctgagg
     2941 gttatttcgg gaaaatcaat cagtttatgg agcaggtcta ttctcagggg attatttatc
     3001 cacccaagga aaaggttttt caggctctct tgacaacact gcttgaagaa gttaaggtgg
     3061 taattctagg gcaagacccc tatcacggac caggtcaagc gcagggcttg agtttttctg
     3121 tacctgactc tatcccagct ccaccatcct tgcaaaatat cttgaaagaa ttgtcagatg
     3181 atatcggagt taagaaatct catgatttga cagcttgggc tgagcaagga gtcttgcttc
     3241 ttaatgcttg tttgactgtt cctgctggac aggccaatgg tcatgctggt caaatctggg
     3301 agccttttac tgatgctgtg attcaggtgg tcaatcatct agatagacca gtcgtttttg
     3361 tactctgggg agcttatgca cgtaagaaga aggccttagt taccaatcct catcacttga
     3421 ttatcgaatc agcccatcca agtcctttgt cggtttatag aggattttgg ggttccaagc
     3481 ccttttccaa ggccaatgca ttcttaaaag agacaggaca agagccaatc gattggctta
     3541 gataaggaga aaatatgcct cagttagcga cgatttgcta cattgataat gggaaagaac
     3601 tgctcatgct ccatcgtaat aagaaaccca atgatgtcca tgaagggaaa tggattggtg
     3661 tgggtggtaa gctagagaga ggagagacgc cccaggaatg cgcggcgcgt gaaatccttg
     3721 aagaaacagg gctcaaagcc aagccagttc taaaaggtgt catcactttt cctgaattta
     3781 caccagattt agactggtac acctatgttt ttaaggtgac ggagtttgag ggcgacttga
     3841 ttgactgcaa tgaggggacg ctagaatggg ttccctatga cgaggttttg agcaagccga
     3901 cttgggaagg tgaccacacc tttgttgagt ggcttttaga ggataaaccc ttcttttcag
     3961 ccaagtttgt ttatgatggg gataaattgt tggataccca agttgatttc tatgaataaa
     4021 ggagaaagca gatgctacta atcaaaaatg gtcgtgtaat ggatcctaag tctggtttgg
     4081 atcaagtttg tgatgtctta gttcaagatg ggaaaattat caaaattgcg cctgagatca
     4141 cggaagaagg agcagaaacg attgatgcta ctggtcttgt ggttgctcct ggtttggtcg
     4201 atattcatgt gcatttccgt gaacctggtc aaacacataa agaagacatt catactggtg
     4261 ccctggcagc cgctgcaggt ggttttacta ctgtcgtcat gatggctaat accagtccaa
     4321 ccatttcaga cgtggagact ttgcaagcag ttctccagtc agctgccaaa gagaagatta
     4381 atgtcaagac agttgcgacc attactaaaa actttaatgg taaaaacttg actgacttta
     4441 aggcgctctt agaagctggt gcggttggtt tctctgatga cggtattccg cttgagagca
     4501 gtaagattgt caaggaagcc atggaggaag ccaaaaaact caataccttt atcagccttc
     4561 atgaggaaga tccaggtttg aacggtgttc ttggctttaa tgaaaatatt gctagagaac
     4621 atttccatat ctgcggtgct actggggtgg ctgagtacgc tatgatggcg cgtgatgtca
     4681 tgattgccta tgcaactaaa gcccatgttc acatccagca tttgtctaag gaagaaagtg
     4741 ttaaagtagt ggagtttgct caggggttag gtgcagaagt cacagcagaa gtagcgccac
     4801 agcatttctc taagacagaa gcacttcttt taacacaagg tagcaatgct aagatgaatc
     4861 caccgcttcg tttggaatca gaccgtcgtg ccgttatcga aggtctcaaa tcaggtgtca
     4921 tcacagttat tgcgactgac cacgcgcctc atcatgtaga tgaaaaaaat gttgaggata
     4981 ttaccaaagc gccatctggt atgactggct tagaaacatc cctgtctctc ggcttgacct
     5041 atttagtaga agctggtgag ttgagcttga tggaattact tgaaaaaatg acatacaacc
     5101 cagccaagct ttacaacttt gaagcaggtt acttggctga gaatggtcca gcagatatca
     5161 ctatttttga tgccaaggct gaccgccttg tggactccca ttttgcttcc aaagcagcta
     5221 attcaccatt catcggtgaa accttaaaag ggcaggttaa atataccatc tgtaagggac
     5281 aaatcgtcta tcaagcttga taggagttag aatatgaatt attttcgaaa acgtagggag
     5341 agacaagcga aatctaatag tggaatttac tgtcccgcag ctaatcgttc caaaattcaa
     5401 tatgaaacta aagaaaaagc tgaccatgcg gttcaatatg ataacggagg tttagttaga
     5461 agctattatt gtcgtacatg tgcgtgttgg catactactt caaaatctaa taaacctccg
     5521 ctaagtttga aaaactatgg tctgaaactc tttggtttag ataaatcaga atagaaagag
     5581 aagtatgtat aagacaaagt gtttacgaga gaagttagta ttatttttaa aaattttctt
     5641 cccaatcctg atctaccaat ttgccaatta ttctgcctct tttgttgata ctgcaatgac
     5701 aggtcaatac aacactatgg acttggctgg tgtatctatg gcaaccagta tctggaatcc
     5761 tttctttaca tttctaacag ggattgtgtc agccttggtg cctatcattg gtcaccatct
     5821 tggtcgaggc aaaaaggaag aagttgcgtc tgatttttac caatttattt atttggcctt
     5881 gggcctatct gtggtcttgc tggggatggt acttttcttg gcaccaacaa tcttgaatca
     5941 tattgggtta gaagcagcag tagcggcagt agcggttcgc tatctttggt ttttatctat
     6001 cgggattatc cccttgttgc tctttagcgt cattcgttcc ttgctggatt cgctgggctt
     6061 gaccaaactg tccatgtacc tcatgctttt gttactccct ctcaatagcg gatttaacta
     6121 tctcttgatt tacggtgcct ttggtgttcc agaactggga ggggctggtg ctggtttagg
     6181 aacatccttg gcctactggg tcttgcttgg gatttctgtt ctggttttat ttaaacagga
     6241 gaagctcaaa gccttacacc ttgagaaacg aattccactt aatatggata aaattaagga
     6301 aggagttcgt ttaggtctgc ctattggggg aactgtcttc gcggaagtgg ctatcttttc
     6361 agtggttggc ttgattatgg ctaagttttc gtccttgatt atagctagtc accagtcagc
     6421 tatgaacttt tcaagtctta tgtacgcctt tcctatgagt atctcatcgg ctatggctat
     6481 tgtcgtttcc tatgaagtgg gagccaagcg atttgatgat gcgaaaacct atattggtct
     6541 aggaagatgg actgccctca tttttgcggc cttcacctta accttccttt acatttttag
     6601 gggaaatgtg gccagtcttt atggtaacga cccaaaattt atcgatttga cagcgcgttt
     6661 tttaacttat agtcttttct tccagttagc agataccttt gcggcgccgc ttcagggaat
     6721 tttgcggggg tataaggata cagttattcc tttttacctt ggtttgcttg gttattgggg
     6781 cgtagcaatc cctgtggcta cgctatttga ttccctaaca gattttggag cttattctta
     6841 ctggatcggc ttgattatta gtttgattgt gagtggggcg ctctaccgtt ggcgtttaac
     6901 tgtgattatg aagagatttg aatctttagc aaaatccaaa cgctaaaaag tttgtgaaaa
     6961 aatattcttg ataagaaaat cccttgtttt cacggggttt tcttttttat tttgtgaaat
     7021 ttcttttaga aaaactttga cagtatttgc caaaaacggt aaaatagtaa ggtaagaaga
     7081 aagttagaaa ggcaagaaga tgtcaacttt agataaaaat cttttgctag aaatgttccg
     7141 taagatggaa gaaatccgtc gcatggactt aaaaattgca caattagtaa agaaagggaa
     7201 agtgccagga atgacgcact tttctgttgg tgaagaggca gctaacgtgg gggctatgtt
     7261 agctctcaat ccagatgatc tgattacctc aaaccaccgt ggacacgggc aagctattgc
     7321 taaagggatc gacctcaacg gaatgatggc tgaaatcctt ggtaaataca ctggaacctg
     7381 taaagggaaa ggtggatcta tgcatatcgc tgaccttgat gctgggaacc ttggtgccaa
     7441 tggtatcgta ggtggtggta tggggatcgc tgtcggtgca gccctcagtc agcaaatgca
     7501 aaataccggt aaaatcgttg tctgcttctt tggagatggt gcgaccaatg aaggtgtttt
     7561 ccacgaagca gtgaacatgg cttctatctg gaacctgcca gtcattttct attgcattaa
     7621 caacggttac ggtatctctg cggatatcaa gaaaatgacc aatatagaac atatccatca
     7681 acgtagcgcc gcttatggaa ttcctggaat gttcatcgaa gacggtaaca atgtcatcga
     7741 tgtctatgaa ggatttcaga aagctgtaga ccatgttcgc agtggcaatg gtccagtctt
     7801 gattgaaagt gtaacttatc gctggctcgg tcactcatca tctgaccctg gtaaatatcg
     7861 tacgcgtgaa gaagtggaat tgtggaaaca aaaagatcca atcgaaaacc tccgcaatta
     7921 ccttattgaa aataacattg caagtgccga agaattggaa gaaatccaag cgcaagtaaa
     7981 ggaagcagta gaagcttctg ttaaatttgc agaggaaagc ccattcccac cgcttgaatc
     8041 agcctttgaa gatatttacg cagactaagg agaaagagat aaaatggaaa caaaaacaat
     8101 gtccttccgt gacaccatta tccttgctat gtctgaggaa atgcgtcgcg atgaaaatgt
     8161 gttcttgatg ggagaagacg tcggtgtctt cggaggagac ttcggtactt ctgttggaat
     8221 gcttgaagaa tttggtccag aacgcgtccg tgactgtccg atttctgaag ctgccatctc
     8281 tggagcagca gcaggagcag ccatgacagg acttcgtcca atcgtcgata tgaccttcat
     8341 ggacttctct gttattgcca tggacaatat cgtcaaccaa gctgctaaaa cacgttacat
     8401 gtttggtggt aaaggtcagg ttccaatgac tgttcgttgt gcagctggta acggagttgg
     8461 ctctgccgcc cagcactcac aatctctaga gtcttggttt actcacattc caggacttaa
     8521 ggttgtggca cctggaacac ctgcggacat gaaaggcctg cttaagtctt ctatccgtga
     8581 taaaaaccca gttattatac ttgagtacaa gtcagaattt aaccaaaaag gggaagtgcc
     8641 agttgatcca gactacacaa ttccacttgg ggttggtgaa atcaaacgcc aaggaacgga
     8701 tgtaacagtt gttacttatg gaaaaatgct tcgccgtgtg gttcaagctg ctgaagaatt
     8761 agcagaagaa ggaatttcag ttgaaattgt tgacccacgt acccttgttc cgcttgataa
     8821 ggatatcatc ataaactcag tgaagaagac tggtaaggtt gttctggtca acgatgccca
     8881 caaaacaagt ggctatatca gtgaaatttc agctattatt tcagaatcag aagcatttga
     8941 ctatctagat gcaccaatcc gccgttgtgc aggagaagat gtgccgatgc cttatgcaca
     9001 aaacctagaa aatgcaatga ttccaacagt tgaaagtatc aaagatgcaa tccgaaaaac
     9061 ttataacaaa gaatagagtt acataagata agttatgtaa ataaaataaa gctgacgaga
     9121 aactttgtat cttttaggtg cagagctctt cgtcattaat atcttatatt cgagcacggg
     9181 ctaaaagctc ggaaaaaaga taaatctcct tggcttcatc gaagccatcg tcgatttcct
     9241 atttttcagt cgcttttgac gccctttgta tcataaatag aattggagag gtcatggctg
     9301 atgacaagct aagagcgact cctgcagcta gaaagttagc ggatgattta gggataaacc
     9361 tctacgacgt ttctggctca ggtgcaaacg gtcgtgtcca caaagaagac gtggaaactt
     9421 ataaagacac aaacgtggtt cgcatttcgc cacttgcaaa acgaattgcc ctcgaacata
     9481 acattgcttg gcaggaaatc caaggaaccg gtcatcgtgg taaaatcatg aagaaggatg
     9541 ttttggccct gcttcctgaa aatatcgaaa acgatagcat caaatctcct gctcagattg
     9601 aaaaagtgga agaagtccct gataacgtaa caccatatgg tgaaatcgag cgtattccaa
     9661 tgacaccaat gcgtaaggtt attgcccaac gcatggttga atcttacttg actgcgccaa
     9721 ccttcaccct caactatgaa gttgatatga ctgaaatgtt ggctcttcgt aagaaggttc
     9781 ttgagccaat catggaagca actgggaaga agactactgt aacagacctt ctttcgcttg
     9841 cagttgttaa gactcttatg aaacacccat acatcaacgc ttcattgaca gaagatggca
     9901 agactattat cactcacaac tatgtcaatc ttgccatggc agttgggatg gataatggat
     9961 tgatgacacc tgttgtttac aatgctgaga agatgagtct ttcagaacta gttgtagcct
    10021 ttaaggatgt tattggccgt accttggatg gtaaattggc tccaagtgag ttacaaaatt
    10081 caacattcac aatcagtaat ttgggaatgt ttggtgttca gtcctttggc ccgattatta
    10141 accaacccaa ctcagctatc cttggtgtca gttcgacaat cgagaagcca gttgtcgtca
    10201 atggtgaaat tgtgattcgc ccaatcatga gtttaggatt aaccattgac caccgtgtcg
    10261 tagatggtat ggctggtgct aagtttatga aggacttgaa agagttgatt gaaaccccaa
    10321 tctcaatgtt gatttaagag caagagtatt catttttaag atatagataa aggaaggaag
    10381 acatggcctt agaaataatt atgccaaaag ccggcgtgga tatgacagaa ggacaaatcg
    10441 tccaatggaa taaaaaagtc ggagaatttg taaaagaagg agaaatcctt ttggaaatca
    10501 tgactgataa agtcagcatg gaattggaag ccgaagaaga tgggtacttg attgccattc
    10561 tcaaaggaga tggtgaaact gtccctgtaa cggaaattat cggttacctt ggtgaagaaa
    10621 gggaaaacat cccaacagct ggagcagcat cgccagaagc tagccctgta cctgtagcaa
    10681 gtacctcaaa cgatgatggt aagagcgatg atgcttttga tatcgttgtg attggtggag
    10741 gtcctgctgg ttatgttgca gccattaaag ctgcccaact cggcggtaag gttgcccttg
    10801 ttgagaaatc tgaacttggt ggaacctgct taaaccgtgg atgtattcca accaagacct
    10861 accttcataa cgctgaaatt attgaaaata tcggtcatgc tgcaaatcgt ggtatcgtga
    10921 ttgaaaatcc taacttcact gttgatatgg aaaaactttt agaaactaaa tctaaagttg
    10981 ttaatactct tgttggtggt gttgcaggac ttcttcgtag ctacggagtt actgttcata
    11041 aaggaattgg tacaatcact aaagacaaga acgtcttggt aaatggttct gaattgcttg
    11101 aaaccaagaa aatcattctt gctggtggtt caaaagtcag caagatcaac gtccctggta
    11161 tgcaatctcc acttgtcatg actagtgatg acattcttga aatgaacgaa gtgccagaaa
    11221 gccttgttat catcggtggt ggagttgtcg gtatcgaact cggtcaggcc ttcatgacat
    11281 ttggttcaaa agtgactgtt atcgaaatga tggaccgtat agttccagct atggatgcgg
    11341 aagtttctaa gaaccttcgc ttgatccttg agcgtaaagg aatgaccatc ttgactggta
    11401 ctaaactgca agaaatcatt gaggaaaatg gtcaacttcg tatcaaggtt gaaggaaaag
    11461 acgatatcat cgcaagcaaa gctcttcttt caattggtcg tatgccagac cttgaaggta
    11521 ttggagaggt tgagtttgaa ttggatcgtg gttgtatcaa ggtcaacgaa tacatggaaa
    11581 cttcagttcc aggcatttat gcaccaggtg acatcaacgg tactaagatg ttggctcacg
    11641 cagctttccg catgggtgaa gtttccgctg aaaatgccct taaaggaaat catgcagttg
    11701 ccaaattgaa tttgactcct gcagccatct acactctccc tgaagtagca gcagtaggtt
    11761 tgacagaaga acaagcccgt gagaaatacg atgttgccat cggtaagttt aactttgctg
    11821 ctaacggtcg tgctattgca tctgacgcag ctcaaggttt cgtaaaagtt atcgctgata
    11881 agaaatacgg agaaatcatt ggtgtacaca ttattggtcc tgcagccgca gaattaataa
    11941 acgaagcatc aagcatcatc gaaatggaaa tcactgttga ggaaatgctg aagaccatcc
    12001 acggacaccc aacttactct gaagtgatgt atgaagcgtt tgcagatgtt ctaggaatgg
    12061 ccatccattc acctaagaaa aaataaaacg aagatagatt agactggaag gttatttcca
    12121 gtctctatca tataaagtaa agggatatca tgaaatacat tatcaatcat tcaaatgaca
    12181 ctgcttttaa tattgccttg gaagaatacg cctttaaaca ccttttggat gaggatcaaa
    12241 tcttcctact ttggattaac aagccatcta tcattgttgg tcgtcaccag aacactatcg
    12301 aagaaatcaa ccgtgattat gttcgcgaaa atggtattga ggtagttcgc cgtattagtg
    12361 gtggtggagc tgtttaccac gatttaaata acctcaacta cacgatcatc tccaaagaag
    12421 atgaaaataa ggcatttgac ttcaagagct tctcaactcc ggttatcaat accctggctc
    12481 aactcggggt taaagctgag ttcacaggtc gtaatgacct tgagattgat ggtaagaagt
    12541 tctgtggcaa tgcccaagcc tatatcaacg gccgtatcat gcaccacggt tgcttgctct
    12601 ttgacgttga tttgtcagtc ctcgcaaatg cccttaaggt ttcaaaagat aaatttgaat
    12661 caaaaggtgt gaaatccgtc cgtgcccgtg taaccaatat tatcaatgaa ttaccaaaaa
    12721 aaatcacagt cgaaaaattc cgtgatttac tcttggaata catgaaaaaa gagtacccag
    12781 agatgactga atacgtcttt tcagaagaag aattggccga aatcaatcac atcaaggata
    12841 ctaagtttgg aacttgggac tggaactatg gtaaatcacc tgaatttaac gtccgtcgtg
    12901 gaaccaaatt cactagtggt aaggttgaag tctttgctaa cgttactgaa tcaaaaatcc
    12961 aagacatcaa gatttatggt gacttctttg gtattgaaga cgttgctgca gtagaagatg
    13021 tccttcgtgg ggtgaaatac gaacgcgaag atgttcttaa ggcgctaaaa accattgata
    13081 tcacacgcta cttcgctggt attagccgtg aagaaatcgc tgaagcggta gttggataaa
    13141 tcaaaaaaag aagttggcca acttcttttt ttgatattta tttacataat ttaaaatacg
    13201 tgaaatcata aactatctag agcattcttt tgttcatcat taacaatatg ggtatagagg
    13261 tcagtgactt gtgtgctggc atgtcctagt tggtgactga ctaaaacttg tgatttagtc
    13321 gcatcataga gcctagttgc tagcgtatgg cgcagtttat ggggtgttac acgtacttta
    13381 aaatcctctg agtatttagc aaccattttc tcaacgctag aagcatcgat acgattagga
    13441 acacctctgt agagagttaa aaaaagggct gtatctgttt tttccgtttt atagcgttga
    13501 ttccgaatgg ccagataatt ctctaaataa ggtttagcaa aagcagcgac attgactgag
    13561 tcacgtttgc caccttttcg agtaacatca ataaccatca tttttagatt gagatctctt
    13621 agatctagat taacagcttc agataagcga acaccagatg ccaagagaag ggcaataatg
    13681 gctaaatctc gttctttatt tttgttgaat gatgagagag ctcgatttga aagctgttgt
    13741 gggtgctctt gatcgatata agttagaaaa ccttctgttt catcacctag aaagagtttt
    13801 tgcttgatat tttcagctct ggcagcaagg gtttctttct ttttcttggt tgaaactttt
    13861 ttcattacat tacgatagaa ataaggttcc ccctgatcgt tttcaacctc ctcggttaga
    13921 tacttgtaaa gactagaaag tgctgataag gttcgattga tagttgtctg tgaaacacct
    13981 tgttttgttg tattagcatt cagcaaggga cgttcacgta gataaaggat aaaggattcc
    14041 atgtctttct tagacatatt ttccaaaact gataaaggaa tatcggatat tttatcagcg
    14101 tttgaaatac cagactccaa aacccagctg aaaaatcggt catattcctt aaggtattcg
    14161 tacagggttg taaaactgta gggcacagcc agcttagatt ggtagtattc cagaacatac
    14221 cagggcatga gttgttttag tttgtcgatt cgttccagta aaatctcacg tttcatgtat
    14281 tttctccata agtaagtata ctagtagtat agcatagact tgtatatttt tcaagaaaat
    14341 tatagttttt cagaaagatg ttataggagt ttttcaaagt gataaaaaga cttagaccta
    14401 caaacaaaac agaataagga aaataataaa aatctcaccc actaaacttc tgttaatact
    14461 acataactga agagctatat aaggagctat gagatacaaa acacattgta taatagattg
    14521 aaactagaat agtacatctg gacttctaaa acattgctag aaattgattt gattgttctg
    14581 attgttttat cctatttcta tttcatttca ctatataatt gctattgttt tctttttcat
    14641 gattttaatc ttactgtaca gatttgatac agtaaactcc tttctagctt tatactttat
    14701 catttctaac ttaattatag tcttattttt aataaagttc aattatttat atgtaaaatt
    14761 cctcatcagt aaaaaataac cgatctcatt tctgagaatc ggttttctaa ataaatcaag
    14821 ctgagtattt acataacata aattatgtaa atactcatac tacaacaaca aatctttgac
    14881 ttttccaatt tcactttttg gaataaccag gtgaatcata tcacccagat acattctggt
    14941 tgagccgtta actgtttggc tcttgccatt atggacttga gttgtgatga ggacgttgtg
    15001 tggtaagttg agttcatgaa cttgtttccc agcaatttta tcagaaactg gtatttcgat
    15061 aagtgtaact tctccttcgc tagatacttc ttctggaagc attttttcca gcatggcttc
    15121 atagactggc gtacctttga gcaaatccat gataatataa gaaacaagag tgacaagacc
    15181 aagtggcatg aggttgcgaa tatctcctac catctcagtt acgaggatca tagcggttaa
    15241 gggagctttt gatatggctc caaaatagcc actcattcct agaatgacaa atatagggaa
    15301 ttgctcttga ctgacaagtc caagattgac acagataaca ccaactaagg aaccaagcaa
    15361 agaaccaaga gctaaaatgg ggaggaaaat tcctcctggc agtccacttc catagctaat
    15421 catactccaa ataaagcgga tcaaaaagta agctaataaa acttggaaac taaaattttg
    15481 ttcagttaaa gaaaggacaa gctgatttcc gccaccaatg atttgaggta agaagattcc
    15541 gactggtatg ataatgataa aagccaagat gggataataa gccctatcca aatggatttt
    15601 ttgaccaatc aagtcataaa ctcttccaac gtttaataca gctttctcat agagaaaacc
    15661 tgaaaatcca aggaaaattc ccatgacgag atatatccaa tactggtcta gggtcatggg
    15721 aggaatgtta tctggcatat ccaatactgg tgtcaaaccg aacatgagta gagacacaaa
    15781 gtttgctacg atgctggctg ctagagttga gacccagaaa aagcgcgaaa aatggtgata
    15841 gacttcttct acaacaaaga gaagtgctgc aataggagca ttaaaggctg cggctaaacc
    15901 tgctgcagct ccactggcaa tcaaggaacg ttcctctact ggactggatt tgagccactt
    15961 ggcaattcct ttaccaccaa ctgctccaag ttgaatgctg ggtccctctc gacccagcat
    16021 gagtccactg gcaatagcaa gaatacctag cacatatttt ttccaaagaa tgccccacca
    16081 gttgagggac atgaggcctt tcagttcggc ttcgacttga ggaattcctg agcctttaat
    16141 atctttttct gaccgtgtta gtttggcact gagccaacag atgagtatat aaaacaaaac
    16201 cagtacaaaa agattgcgca ctaagtaccc ttgatcttga taaactcctt gtatcaggtg
    16261 gaagcccttt tcaattaaga aacgaaagga tccgacgata attccaacga tgaggccgac
    16321 aatgattcct cgaccaactt gggatagtat agtgctggat gcaaaggcga attctttctt
    16381 agaacggact atttccgact gttcctccat ggtatttcct ttcaattaac tttctttttt
    16441 acctaaaacc agtgatttaa cgggttcaaa gctggttcgg tgaattgggg taactcctag
    16501 ttttgtgagg ccttccagat gtttagctgt gccatatcct gcattagtag cgaaatcata
    16561 gccagggaac tgctgatcgt attccttcat caattcatca cgtgttacct tggctactat
    16621 agatgctgct gcgatagaga gggagttggc atctcctttg ataatggagg tttgtgaaat
    16681 gggcaagtcc agtttcatgg catcaatcaa aaggtgctct ggttgagggc tgagctggga
    16741 gattgcttct tgcatggcta gtttggttgc ttcatagata ttgacttggt cgatgacctg
    16801 attatctatg ataccaattc caatcgacaa ggcttggtct tgaacgactt ggaaaatctc
    16861 cagatgtttc tttttaggaa ttttcttgct gtcgttgaga cctttaatct tacaattttt
    16921 aggtaaaata acggccgcag cgactacagg accagcaaga ggaccacgac caacctcatc
    16981 aatacctgca attaaggtca atccttgctt ataaagttct ttttcataag aaagcatgga
    17041 ttccaagcgc aaattttcat ctaattcagc ttgaatggct cttttatgct tgctgatttc
    17101 cttttgaact cctgagcgat tatccttttc aagatctaaa aaaatagggc tttctaactc
    17161 cttgactgtc acaaggagtt ctttgatttc tttaatcgtt gccatcgagg ccttccaatg
    17221 tatctaaggt atagttaccg agtttgccat cacggacttc cttcacgaag agactgtaaa
    17281 aacggtcata gtcatcacgg aaaccgaggg cgcgggtcat atccataata atcacaggcg
    17341 cttcttcttc aattttcatt tgtttgaagc gttcagccag cttttctgga taatgttctt
    17401 tgaaataatt gataccaaaa atggtaacct catccatagg aagcaactga tccttgatag
    17461 ctccagtcaa tgccaactta agtgcaacag tttcatcctc aaacttaggc cagagaatcc
    17521 ccggtgtatc caagatttcc agatctttat tggttttaag ccattgttga ccttttgtga
    17581 cccctggctt gtttccaaca acagcaatct ttttaccagc caaacggttc atcagagttg
    17641 atttaccagc gtttggaatc ccaataatca tggtacgcaa ggtttcaatc tgaatcccac
    17701 gttctttctg gcgagcaatc ttatcagcca tgagcttctt ggccgcatct gttacaactt
    17761 ttacagtcac ttgctctttg gagttgatag ctagcgtctg gattccttgt gattcaaaat
    17821 actgacgcca ttccttggtc attgctggat cagccaagtc ggccttgttt aaaatcaaga
    17881 gttttggttt atcaccaaca atcttggtta acataggatt ttgactagat agaggtaagc
    17941 gtgcatcaac taaaatcgtc acaaaatcaa caaattttaa attctcctgc acctgtcgac
    18001 gagctttaga catgtgacca ggaaaccatt gaatagtagc cattgagttt tttcctttca
    18061 tagcaaggat ttagatcccc tattttattt tactattgtt tgaacataga gagttttcaa
    18121 atgaatgatg tccaaacagt tcttgtttta tgacatagaa atctacttta tattatatca
    18181 tgccttcttt attttgtccg atgatagcct tttaccctat atagaaaaaa gccatcaaat
    18241 gatgactttt cagagggagc aaaaaactgt tcccgtcata ttatgaacca aaagaactaa
    18301 actaccaaca gctaataggc ctaaagctgt aagtgcagaa gttgatgaac ctgttgcagg
    18361 aagagtttcc tgctgataaa taagagcata acttacttca ttatcagtag gaattcctgc
    18421 ttgaatcttg gtttgttctt catcaccttt ttaaacttta tttcctaata gtaaacacta
    18481 ttttttattc tcaaaaattg aacttctaaa atcatttgtt tggtcaagat aggctttaaa
    18541 gattgctctc ttcaacttat gaacggcact gtcgatttct ggatcataat tactccaacg
    18601 tggaccttca gcatccttga gaacagcttg gtccatgagg gcttgcaatt catccacatt
    18661 attgatagtc tttgtgccat agcttggcca tggttttgtc ggatctttaa aggtcacctg
    18721 cttcaagttt ccaaactgat ccactcgttc ttggtacata gctgtcttaa attctgccca
    18781 agttttatac ttaccgtcaa ataccttttt caaaacaagc tcatcggtca ccaagccccg
    18841 ttctttacca taaagattga tagtttgccc ttgttgttta gcatcttctt cgtattggtt
    18901 tgagatataa ggtaccattc catccttaaa gcctttggca gccaaaagtt cgtacgcaat
    18961 cctacgtccc ataaggtccc ctggtgtgcc tttctcactg ctgagagctg aatagattgg
    19021 ggcaaagagt ttgatggtat agtagccatt tcgttcatag tcgccagact ggtactcacg
    19081 agctgataag atgttgtggt caatcaaact ttcaaaacta ttcaggtttc gggcctctgc
    19141 ttctgtcaat tctttgacta cgttagtggc ataaacctca tttccatctg ctggatcttt
    19201 cacatacttg ttctcaattt ttctgagagc cgccattttc tggtaaacac ttagtttatt
    19261 aacgattgac tgcccttcga gatattccat catgtagata aggtcaaaca tgttatggac
    19321 atagttctga agatctgctg cgttttggaa tctctctgtc ggatccaaga cttgaagacg
    19381 ggatccctct gtactatctg attttgagtg tttcaagata gaattaatgg taatggttgc
    19441 gtcacttggt tggtcagggg cttgcaataa gccttttgcg aagaactctg gtcccaagcc
    19501 atttcttcga ccatagccac caaggtaaat atcctgatcc gaatcatggg tcatttcatg
    19561 ggtataagta atggctccat ccttgtccag catgcggtaa gacatatagt agacgccgtc
    19621 ccctgtagcg taggctccat gctggttgtg tactacctta ttgccaactg gtccaaagaa
    19681 gttcttcata gctggattgg agctatcaaa cttagcctcc gctgtagctt ttcctgatgt
    19741 tgtgtcatcc ccaaacttat aggcatcata aaggagaatc gtacgataga gtttttcgcg
    19801 tgactgttca tctaaaatac gataccaata atcgtagtga tctcgctgac gtttggctgt
    19861 ttcacgcgca ttttcttcaa caaaatcatt gagagccttg cccgctttat ggtcactact
    19921 gcggtagcga tcataagctc caaatcctag actagacatg gtcgagatga caaatacgga
    19981 tctctctggc aaggtcagga gaggcaagac catattgcgg tatttccatg tggcactcgt
    20041 gatacgatca taaacaccga tagaatactt ggtgccagct aacccttgct tcgttttcac
    20101 ctcttcgata gtggattttt cttcgacaat gtaagcctta gtctctgatt taaaccagtc
    20161 attattgctt gtatttggta aaaagacttt tcggtaatgt tccagcgtgc taaacaaatc
    20221 tgtcgttcca tgttgactgg caagactgat accataagta tcgacattat tcttagctag
    20281 aagattgtta aagccagatt tacctaactc aatcagagta tctagtgggg aagtatttcc
    20341 tttaccaaag aagtctggat gatacataac taggtctttg acattcactt gaccatagtt
    20401 aaagttatac caacgttcta aataagttaa accgagtagc aaggcttcct tattattctt
    20461 gattttatct acaagatagc ctctggtgac tgagttatcg ctagctagac cggcatctgc
    20521 tgacaaaagt tttttcaagc tgtctcccag attttgtttt gttttggaga actggtcttc
    20581 taaatagagc tcggttaact taacttctgg agaaatacca agtgtctttc tgatagcatc
    20641 tgactggtaa tcaagcttct gcaactcagg caagacttcc ttaacaatag agtctcgatc
    20701 atataagaat tggttaggag tgtagagaag tcccgtatta cctagattat attctgctag
    20761 attggcaaaa tcagtctggt acttgagatc aaatttctca gatgaatggt cattatagtg
    20821 aagtaagagt ttgtttgcag tctgtttgtt ggaaacaata tctgtgatta cttggtcatc
    20881 cttcatcata actgcagata agagttcttt ttggtataag agactgttct ccttaaccag
    20941 gtttccgtat ttgacgatgg ttgacttatt ataaaaaggt aacaattttt caatgttctt
    21001 ataaaccaaa gcacggttag cttgataatg ggctatctta gaaaaatcac tgtctttctt
    21061 gccacttgtt gagaggggtt ccaccgttgg tagagtgaga ggatttattt ctgctttttt
    21121 gcttacaatt tgagaagcat ctagcattgt tcctctttct tcaaaggatt ccttgctgac
    21181 gacctcatcc ttctctaaag tgacattgaa aactctatta gccttactac taaatgtatt
    21241 agctaccttc attcctgtat agtggtatcc agtgatggca tttccgtttg ttacattgac
    21301 atcgctaaga acattggtca attcaccagc gtgtttttcc tcaccagaag ttcgatccca
    21361 caaatatcct gccacaccag cgactttacc aaagtgcttg acattattaa tatcaccttc
    21421 cgcataactg ttctgtatat gcgcatcttg gtctactaga cctgcaagac caccgacagt
    21481 ctgatctgac ctattggtgt ttgacgaaat ggttactgtc gctttggatt tagcaataga
    21541 cgcatttttt cctgttaaat gaccgaccag accgccaata ttgtaggcat cagtcgtttc
    21601 ataggtattg acaattcttc ccttgaaact gctctctgcg atgcttgatt ggtctgcctt
    21661 agccaacaaa ccaccgacac cacgttctcc agccagaaca ccatcaacat gaacttgttt
    21721 aatctttgtg ccattcgtag cttcatttgc tagtgaacca atatcatttt tccctgaaat
    21781 agcaacattt tttagactca gtttttctac tgtagcacca ctcaagtttt caaacagagg
    21841 ttttttcaaa ttatagatag cataattctt gccatctttt tcaccgatta aacgaccagt
    21901 aaaggtgtcc ttgatatagg atctttcatc aggaccaagc tccacttcgt tagcattcag
    21961 gctggccgct aaatgatagg ttccagaggg attttggttt atagctttga ccaggttgct
    22021 aaaggaagta aagtttgtat tttcctcttt agccttctta tcgaggtaga aggtgaaatt
    22081 gtcgacatat ttattttcta gttcttgctg gagtttctca gctttggctg tgattttata
    22141 aactgactgc ccatttcttt tctcttcagt tattgaagct actggtatat agacatcttt
    22201 aaatgctgaa gattttacct tgacaaagta agtatccgta ttctctggaa ttccatccaa
    22261 tgaaacatgt tgtctgtagg ttccattcgt ctgactatac aactcaatat cagaaacatt
    22321 tcttaattcg agttttttct ctggttctgt ttgtccattc tctgatgttg tattacctga
    22381 attttctggt tttgttgcag ttccgttttt ttctggttga tttgattctt caactggtgg
    22441 ttttgaatca ctaggtttat tggatacttc tccagtattt tcgttagcta ttttcccaga
    22501 gtttgtttgt gtttcttctg caggttgaac tggtttttct gtttcttgat ttgaggtacc
    22561 ttctactgtg ccttcatttg gatttactgg aacttcttct acagtttttt ctgaattttc
    22621 atttttagag tcattatgtt ctggtttatt tgattctcca actgaggttg tcgaatcact
    22681 aggattactg gacacttccc cagtattttc gctagatgta tctggtgata ctttctctga
    22741 attcgttgtt gattcttctg caggttgaac tggattttct gcttcttgaa ttgaggttcc
    22801 ttctgtagta ccttcatttg gatttactgg tgtttcttct gttggtttta ctggaacttc
    22861 ttcagttttt tctggacctt gttctttggt cttctcaacc ggagtttcag gttttacttg
    22921 ctcaatatta cccttatatt ctggcaatgg ggctacctgc tctggttcac ctttatcact
    22981 taccacagta tctggcgact ctggttgaac ctcagtctca cctttgtcgg tcacaactgc
    23041 ttcgggtaat gtcggttgaa cttctggttc gcctttatca cttactacag cttcgggcaa
    23101 ctcaggctga attgcgggtt caacaataga tccagactgt acgtccttat gttctacacc
    23161 agtctcaggt tgttccttta taacttgagt ttttttagta cctttttcga ctattcttgg
    23221 actaggcgca gtcgttgaag ttgaaacaat ttctcgcgaa acttcttcct tgtttacaga
    23281 gaatattctg acgatttcaa ctttcttacc taatttacct tcttgtttta ctcttacagt
    23341 tccttcagct aaatcaggat tttcttgaat ttcttcttga aaatctattt ttgtctctat
    23401 agtttcctca cgatataaga gttcaggttt gttcaattga cctgataaaa cttcatcctg
    23461 tggatttaat gtatttaccc cagtcttttc ttttggagaa atcttctcct ctttcttcgt
    23521 ttctagattc ttatgttcgg ctaattgttc ttgagaatct gaagattgtt tctcttcttt
    23581 tcttggattg attaattcag tagagaaagg tttttcaact acttgaactt ctgtcggctt
    23641 agttgaagaa acaggtgttt gttcctgaat agcttgtact gttgatggat ggtctacaaa
    23701 atttggtgta acattataat ccaccttttg ttgttttgta ggagtggctg ctgatttttc
    23761 ttgattactt acttcaaaat cagaagtcgt ttttccctct ttgatatatc caatataagt
    23821 gtaacctgaa atctctttag gaagaggtaa tttttctcca gaggtcaatt catagtccgt
    23881 attgtaattt agcaaaagat gattttctaa agcatggact gaaactaaga caccatttcc
    23941 cattcccgca accaatacta aatgtaatac cgttttattc ttaacctttt tcttggaaac
    24001 agcaaaaatt aaaattccca gagcagctaa gctagcacca gcaactaggg cttgcctctc
    24061 attcttgctt ccagtatttg gtaattccgc cagttgattt tgagaattta acttataaac
    24121 aagataataa gtttcatcat cattctccac gtatgtcgga atatcataga caagctgctt
    24181 cttttcttct gatgatagct ctgaatctgc cacatattta tagtgaactc ccgcagtttc
    24241 ttgagcatcc acagatgaac tagctaatac agacataaaa aataaacttg aaatcgttgc
    24301 agatacaagt cctactgata attttctaaa tgaaaaacgc tcttgttttt caccaaaata
    24361 cttttccatt attcctcctt gaaataaaat ttatatatgt tacaaagacc tttattatat
    24421 tagtgtatta tctattatct atagaaaagg cagtatacct taattatact cttaatttac
    24481 aaaaaagtct taaaattgag atgcgctttc atactttgtt ttatattatt tgggggtaca
    24541 ataacaccta ccatgaaatt tacacggtag gtgttactca tatcactaat cgttctaaaa
    24601 atggtttgag gcagttgagg agaattcctt ctatccagct tccttgtgct gatgagcgat
    24661 ggtcttcctg caggcttttt tttagaaaat ctcggacttg ttctggtgcg atttcaaatt
    24721 caaaggcttt cattttatag aaaaagtcga tgagatgatc tgacaggtat tcagttgaaa
    24781 agggtacttc accacttttt cgatattcta ataagagtct agaaaatcga gctttttctt
    24841 caggaagctc acgaaaatag gaattgagga tccaagtctg cttctgtttt ctttcaattg
    24901 gatcctgact ggcaattcgt tggtcttttt ccagctcttt ttggtattgt ttggccttga
    24961 tagctcgttc tgctctattt ttaccaaaaa gaattttttc ccacttgcgt tcttcttgag
    25021 tcagggtctc tgtaaagcca aagtaatctt gataagcacg ctctgcgggt cccatggcta
    25081 gaaccagatt gtctgcatat tgcttggcga ttttatccct cttcttgcgt tctttctctg
    25141 cctggatacg gagttcttgt tcgtagtcaa ttttctcctt gcctagcttg acaaggtaga
    25201 gttggtcatc cgatttccca agtaaaaagg gtttgataca cttttcaagg acttcttcca
    25261 tccgagcctt tttctttggt tccgccttgg tccaacttcc tccctgaaag acttctagga
    25321 aaagctggta gtctctctca ggcgcaaatt gattgccacg attgggtttg aaaacacctt
    25381 tttcccagag ccattttaga agtcgctcgt caaagtcact tttattgacc ttgatttttt
    25441 cctttttctg agcttttctg gttagatttt caacctttct gagcagtttt tcttcctctt
    25501 ccaattgctg gtcaaggggc aatcgatgaa aatgacgaac acagtcgcta ccaattggaa
    25561 agaggcgttg gcctgtgaca ccgttaaaga gttcataagc gtatttgatg gcatttcgac
    25621 agacacaatt gctacggcca ataccgttaa aaatcaagga aacttcattc cattccttgg
    25681 tagcttgttc ccaagtatcc gctttcgaag cctgtaaaac tgcatcgtgc agggattttc
    25741 taactggaag tgtcatgagg tctcctttct aatactcaat aaaaatcaaa gagcaaacta
    25801 gaaagctagc cgcagtcagc tcaaaacact gttttgaggt tgtagataga actgacgaag
    25861 tcagtaacca tatatacagc aaggcgaagc tgacgtggtt tgaagagatt ttcgaagagt
    25921 ataagttata cttttacaac ttgaacctcg tctttaccga gtaaaatcaa gtatttttca
    25981 atattttcaa tcgaataggc tcgtgataaa gcctcttcgt atagagctaa ctgaccacga
    26041 tagcggtcta cgagttgact tggttcatca tagcggtctg tcttgtagtc gaacagaaca
    26101 attttgtttt cgtaaagcag atagccatca aggataccac ggacaacaaa gtcttcctga
    26161 ctcttttggt ctcgtttgag catggagaaa ggttgctcgc gatagagatg gtcggtatta
    26221 gcaagaattt cctgaccgag tgctgtgtca aagaaagcaa gaattttatc aagattgatc
    26281 ttgtctctga cagcttggct agtttgaact tgtttgagtg tttctgttaa gctagcaagg
    26341 gttagttgct ggctgaggtc aattatctgc atgagttcgt gagtagcact accaatctca
    26401 gctccagtta ccttttcttt ggttgaaaaa tctggcaaat cgaagctgat tttcttgcct
    26461 actgactgac cttgaccagc aatctcgaca ccttccatat ccataactgg ttcgtagaat
    26521 ttcttgattt gacttggggt ttgaacacta ggaagttcaa tagctgcgcg gtgaagagta
    26581 ttataaactt ccacctcctt cagcatttcc agagcttctt tgatggtatc tgactgacga
    26641 ttgtctgctt gggagctatc ttggagagga ctcttggttt ccaactctcc gatagcttct
    26701 ctggtcaact gatcttcgtc aataaaacga taactaaagt tgagcttgtc cttagtaaac
    26761 actttactga tagcccaaag ccaatcttgg aaattccgtg cttgcagtct agtattgcta
    26821 tttagtttcc catttttggc tgctgggtat tccttggatt ccagcttttc acgagaaccc
    26881 ttgccgacaa gatagagctt tttctcagcc cgcgtcatag caacatacag caaacgcatc
    26941 tgctcagaat agcttgctag ctgtaattcc tcttcgttct gcctataggt cagactagga
    27001 atggagagtt tgatggtttt aggatagtgg tcttctactg cccctgtctc catcttggca
    27061 atatatttga caccaagacc attctgacga ctgagaatga cttctgacat agagtcttgc
    27121 ttgttgaaat tttgatccat attgaggata aagacgtaag gaaactccag ccctttactc
    27181 ttgtggatgg tcatgagctc tactgcatct tttggcggtg cgacggccac gcttgccaaa
    27241 tcgtgctggg cttctaagac ttggtcaatc atacgaataa aacgcgacaa acctttgaaa
    27301 ttgctctttt caaattgatc agcacgcagt gctagggcat agagattggc ctgcctagca
    27361 ggaccattcg gcaaagcccc aacatagtca taataaaaac ggtcgttgta aatcttccaa
    27421 atcaagtcat agagagagtg ggttttggca tacaagcgcc aagaagctag gatatccatg
    27481 aattgcttta gtttttcaac tagagctgtg tgaatcaagc ctttttgact acttgccatt
    27541 ttttgtgcat tgaccagttt ctcatagaga ttttcgtgga ctttatcctc tgctttctga
    27601 agggacaaac gtgctagctc atcctcatca aaaccaaaca ttggagactt cataagggca
    27661 accaaggcgt agtcttgcag gggattgtga atgacacgaa gagtgtctag catgacttgc
    27721 acttctaggg attggagata attgttttgc tctccgtcag ttttgacagg aatcccgtac
    27781 tcagacaggg cgaggagaat ctggtcatta cgactgcggc tggaggtcag aagggcaatt
    27841 tccttaaagg caacaccttt ttcttgatga agtttcagaa tctccttgat aactaagcgc
    27901 atttcgcctg ttagtttcgt ttctgtttga ctctcttctt cctcacctgt atcgtccttg
    27961 tcgtagagga gaaattctgc cttgttgtct ggattgggag tcagtttggt attggcaaaa
    28021 acaagctggt gcttgttatc atagttgatt tcaccgacct cttggtccat gagacgttca
    28081 aagacatcat tggttgctga cagcacttct gaactactac ggaaattttc cttgaggaga
    28141 atgagcttgc cttcttgggg attttgcgca tagcgttgga atttctcatt gaaaatctgc
    28201 gggtctgcct gacggaaacg atagatggat tgcttgatat ctcccaccat aaagcgattg
    28261 tggccattag acaacaattc cagcatccgt tcttgaatat ggttggtatc ctgatactca
    28321 tcgaccatga cttcatggaa gcgctcctga taagactcac gaacttgtgg gaaattctct
    28381 aaaatctcaa tggtgtaatg gctgatatca gcgaattcaa aggcattttc ctggcgtttg
    28441 cgctgacgat aagcctccac aaaatgactc ataaaggttt ggaaggtttt agctagtttc
    28501 catgtgtctt gatgataacg ttcttgatag tcgagaatgg ttatctggtc tgataattgt
    28561 cctagtttag caaactgggt ctttctctct tcgttgtagg catcagccag gggcttcaaa
    28621 tcagccttac gactggcatt agtcagagct cgaccgtttt tctccttaga gatggcgaca
    28681 acacgcgcaa gcactgcctg ataagcctga ctatcggact cctgatttag ggagcaaatt
    28741 tcatccagaa ttaactgaac attttctaaa taggcagcct ttgcaaactc cttggcatcg
    28801 ttatccagat ggtaacggaa aaagctttcc aaatcccaaa gggcttgttt gatttgctca
    28861 gtcagttttt ctttttcact ggtaaaatca gctttctcaa atcctttgag gaaagattca
    28921 ctcagccact tttgaggatt actggtggat tggaggaagt catagatttt atagacctgc
    28981 tggcgcagac cccgttcgtc cttgccacgc ccagcaaagt ttttcagcaa atgactaaag
    29041 gtctctttct gtttaccttg gtaatgcgct tcaaagacct catgaaagac ttcgttttcg
    29101 agaagaagtt gctcgctttg gttttgtaaa atacggaaat taggtgcaat atcaagcaga
    29161 taaccatgtt tgccaaggaa tttttgtgtg aaagagtcca tggttccgat ggcagcgttt
    29221 ggtaggtctg ccaactggcg tcccaagtgt tgtttgaggt cgacatcatc tgtttcttgg
    29281 attttcttgc tgattttttt ctctaaacgt tctttaagtt cagttgcagc cttgacggta
    29341 aaggttgaga taaagagttg agaaatttcg acaccacgcg ccaattggtc cagaatgcgc
    29401 tctgccatga caaaggtctt tccagaacca gccgatgctg agaccaggat attctgacca
    29461 gaagtgtaga tagcttcgat ttgctcggca gttttctttt gttccttgct cgaatttgct
    29521 tctgcttctt gcagtttttg aatctcctcc tcacttaaaa agggaataag cttcatcgat
    29581 tcaactcctc tcttattttt tcaagccaag cttgcttgag tttttctccg accagacgct
    29641 tgccatcagc taggtccaac ttttctagga aacgggcttg gcccagatgg taattggctt
    29701 caaagcctgt aatagcctga tgttgctgga cgtatggggc aatgcttctg ccattttcag
    29761 tataaggatt gatggcgaac cggcctgcta aaatcttctc agcagctttc ttgtaaagat
    29821 aggcattgta gtccagtagg agctgaaatt cctcatctgt cagttgattc gccttgtttt
    29881 tgttataaaa ttcgcctaaa taactgcttt ctttttccaa gaagagccct tggtatttca
    29941 tagatttgct ggcttctacc actgctcctg ccagactttt taccgccatc agagattgga
    30001 caggttcagc catttccaag tacatggcgc cgaaaaagtt ctgctcccct tctcttttta
    30061 gggcagcaag ataggttggt aactgagaat tgagcccatt aaagaaatga ggaaactgga
    30121 actgagtcag actggatttg tagtctacta ctcctatcgc tccattagct ttcaaacggt
    30181 caatccggtc caccttgcct cgtacaaaga cactgcgtcc attgtctaat tgaataaagg
    30241 cttggtcttt tccaccaaaa tttgcttctt ctttgattgt ttcgatggct ggattgtgtc
    30301 ggagaatatg tccagttgtc cgtgcaacat caagcaaaac ttccttggta aactgggctt
    30361 ccaaactttc ttgataaata gcttcaaatt cgcgttcttg actggtttct tgaatagctt
    30421 gttctagacg ttggtcaaag gaatcttcat taggcaactg caaggcgcgt tcaaagatac
    30481 gatgcaagaa attcccgtga ctacgggcat caggacgcaa acgtaattcc tcctgcaagc
    30541 ctaaaacgta gcgtaggaaa taactgtatt cattgcgata aaactctgtc aaacccgacg
    30601 tagacaggta aaactcctgt ttggcaggat agagagcttg caaggtgtcc ttggctaagg
    30661 tcttgctgct tggactgatt gggatggctg gattttccag accttgctga tctagttttt
    30721 tacctatgac acgcgacaga accttgacaa aagtcaaatc ttgctcagta tcgctcatct
    30781 caccctgctg gtgataggca accagactag acaaaagact gtgataggac cccatatcct
    30841 ccttagacag tcctttgtga ttcatcctct tctctctccg cctaaatcca aaatggatca
    30901 actcttgaag ataggcagat tccttacttt cactttcgtt aaaaaggctt ggagccgaca
    30961 agaacaactg cttacgagca gaattgacca aggaaagcat agtgtagcga tttttcttga
    31021 gattttcact gctggcaatc agtaattgaa cgccttcttc ggtcgtttgg tttaggtttt
    31081 gcctttcttc atctgtcaga agactggtgt tttgagaaat ttttggtaaa ttgtcctgag
    31141 ttagtccaat agcatagaca aagtcagcag tcaatggtgc aatcaaatcg taactctgca
    31201 ccagaacagt gtccactgtt gctggaatgg tacggtattg ggacaaactc attccagaat
    31261 ggagcaaggc taggaagtct tccagactaa cctgtgaacc agcaaaaaca gtcgcaaatt
    31321 gttctaaaac atggcagaaa gccttccaaa cttcggcttg tctttcctgt tctacagctt
    31381 ccaaagtggt tgtcaaatct tgtaactgct tggtcacagc tccttctttt agaaagacac
    31441 tccatttttg taggaggttt tcagcctttt gttttcggct ggcaaagagg gtttcaagag
    31501 gtgctaaaat tctcaggcgg aggacattca aacgctcaag attaaatttt ccatggtggg
    31561 atttggtgaa agtttgctga aaggctggca agccattgat accaagatag cggatatatt
    31621 gctcaaaagc atcaatatca gactgactga ggtcagtata caaatcagtt ctaagaagat
    31681 taatcaaatc ctcctgacga aaacggtaac gttttaaagc taaaatagac tcgacaaact
    31741 gagtcaaggg atgatgagcc atggcttcgc ttctaccaag ataaaaagga atctgatact
    31801 ggtcaaaaat ggttttgaga gataactggt aagaagctac atcccccaag agaatacgaa
    31861 aatgcttgta gctcaggtct gagttctcat gtaatttctg acgaatgcta cgggctacta
    31921 gctccaactc ctccttttgc gtcaaacaag accagatttg taaattttca cggtctttct
    31981 catcgacatc caaagcgagt tctgaaaagt cataagaaga ctccaacaaa cgagaggcct
    32041 tgtcaaaact atccatcttc tcatgagttt gagaacagtc ctgagcaggc gtttggtatt
    32101 tagaagccag atgatggaga aattttacgc tggcttggta gagattgccc tcgctaaaag
    32161 gactggtata ggctttctta ctagcataag ccccgataac aatctcaaca cctttgccgt
    32221 gaagtaagtc cacaacccgc tcttcctcag cagaaaaacg agtaaagccg tcaatgacca
    32281 aggtgatttg attaaaatca ctacttacct tgtcattctc aatagcctca atcaaatggg
    32341 acaactgact tccctgggct aactgacctt gattaagata ggctgttact ttctcaaaaa
    32401 tcaagagtaa atccgccctc ttatcctcat ctgttaaatt ctccaagtcc aaaaaactca
    32461 tctgagattt ggtcatctca tggtaaagct caattaactg ctggatcaat tgaggatcct
    32521 gcttaatagc gccataaaca cgcaagtcct tgggatcgag ttcggcaagg catttgtaaa
    32581 aggccaaccc aagaccgata tcatcaagag tagttttaac tggtaaatca ttcaagacca
    32641 gataacgagc catttgagca aagcgcgtga cggtaatcga aaaagaagcc tgctgggaca
    32701 agcattccag cacggcgcgt tccttttcaa aagaaagaga gttgggggca atgtagaaga
    32761 cccgcttgcc agctgcaact agctcttctg cctctcttgt tagaatttct gtcaaagaag
    32821 ttcgaatatc agtataaagt aatttcatct cagcctcgtt ggaatttttc atcaccctat
    32881 attataccat gattagcctc gtaaatctgt taaaatattt aggccatcct ttcttttctt
    32941 catcatctgc taaatcttaa atacttagct ttacttgtat tagatagaat aagtctggct
    33001 actgaaaatc acataataaa aaagcctcgg taacaaggct ttgagtttta tgattgtttc
    33061 ttaggtacgg aatacacttc aatgtgttgt cccagtatct taatgtcgac tggtagattg
    33121 tctgatttat cgccatcaac atcggactct aattcgatat cagaagaagt tttaatatta
    33181 cgtgccttta tatattcaat attcttgata gaatgattga actatagtaa attgaaacta
    33241 taatagtaca ccgtggatgc taaaatattt ctagaaatta atttgatttc cctaatcaag
    33301 ctgttcgtat cttatttcaa tcta
//
LOCUS       DAVBBO010000019        32531 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ST1
            SAMEA2066453-rid20184263.denovo.019, whole genome shotgun sequence.
ACCESSION   DAVBBO010000019 DAVBBO010000000
VERSION     DAVBBO010000019.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2066453
            Sequence Read Archive: ERR351777
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 32531)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 32531)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980402.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980402.1
            Genome Coverage       :: 176x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:17:33
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,141
            CDSs (total)                      :: 2,104
            Genes (coding)                    :: 1,953
            CDSs (with protein)               :: 1,953
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 16S)
            partial rRNAs                     :: 1 (23S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 151
            CDSs (without protein)            :: 151
            Pseudo Genes (ambiguous residues) :: 0 of 151
            Pseudo Genes (frameshifted)       :: 73 of 151
            Pseudo Genes (incomplete)         :: 76 of 151
            Pseudo Genes (internal stop)      :: 40 of 151
            Pseudo Genes (multiple problems)  :: 32 of 151
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..32531
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2066453-rid20184263.denovo.019"
                     /strain="ST1"
                     /db_xref="taxon:1313"
     gene            complement(293..982)
                     /gene="rplA"
                     /locus_tag="VQU30_000886"
     CDS             complement(293..982)
                     /gene="rplA"
                     /locus_tag="VQU30_000886"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006145049.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L1"
                     /protein_id="HET2447019.1"
                     /translation="MAKKSKQLRAALEKIDSTKAYSVEEAVALAKETNFAKFDATVEV
                     AYNLNIDVKKADQQIRGAMVLPNGTGKTSRVLVFARGAKAEEAKAAGADFVGEDDLVA
                     KINDGWLDFDVVIATPDMMGLVGRLGRVLGPRNLMPNPKTGTVTMDVAKAVEESKGGK
                     ITYRADRAGNVQAIIGKVSFEAEKLVENFKAFNETIQKAKPATAKGTYVTNLTITTTQ
                     GVGIKVDVNSL"
     gene            complement(1189..1614)
                     /gene="rplK"
                     /locus_tag="VQU30_000887"
     CDS             complement(1189..1614)
                     /gene="rplK"
                     /locus_tag="VQU30_000887"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004226069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L11"
                     /protein_id="HET2447020.1"
                     /translation="MAKKVEKLVKLQIPAGKATPAPPVGPALGQAGINIMGFTKEFNA
                     RTADQAGMIIPVVISVYEDKSFTFVTKTPPAAVLLKKAAGVEKGSGTPNKTKVATVTR
                     AQVQEIAETKMPDLNAANVESAVRMIEGTARSMGFTVID"
     gene            complement(1737..2453)
                     /locus_tag="VQU30_000888"
     CDS             complement(1737..2453)
                     /locus_tag="VQU30_000888"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000747760.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M15 family metallopeptidase"
                     /protein_id="HET2447021.1"
                     /translation="MKKRYLVLTALLALSLAACSQEKAKNEDGAAKTEQTAKADGTVG
                     SKSQGAAQKKAEVVNKGDYYSIQGKYDEIIVANKHYPLSKDYNPGENPTAKAELVKLI
                     KAMQEAGFPISDHYSGFRSYETQTKLYQDYVNQDGKEAADRYSARPGYSEHQTGLAFD
                     VIGTNGDLVTEEKAAQWLLDHAADYGFVVRYLKGKEKETGYMAEEWHLRYVGKEAKEI
                     AASGLSLEEYFGFEGGDYVD"
     gene            complement(2456..2926)
                     /locus_tag="VQU30_000889"
     CDS             complement(2456..2926)
                     /locus_tag="VQU30_000889"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HIT family protein"
                     /protein_id="HET2447022.1"
                     /translation="MCLICQRIELIKKGENPYFVKELETGYLVIGDHQYFAGYSLFLA
                     KEHVSELHHLEKKTRIRFLEEMSVVQEAVAKAFAAEKMNIELLGNGDAHLHWHLFPRR
                     RGDMNGYGLNGRGPVWWIPFEEMTAEICQSKPDEIKRLVERLSSEVDKLLEIKE"
     gene            complement(2928..3965)
                     /locus_tag="VQU30_000890"
     CDS             complement(2928..3965)
                     /locus_tag="VQU30_000890"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001077203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M42 family metallopeptidase"
                     /protein_id="HET2447023.1"
                     /translation="MNQTVEYIKELTAIASPTGFTREISNYLVKTLEGFGYQPVRTAK
                     GGVNVTIKGQNDEQHRYVTAHVDTLGAIVRAVKPDGRLKLDRIGGFPWNMIEGENCTV
                     HVASTGQKVLGTILIHQTSCHVYKDAGTAERTQDNMEVRLDVKVSNEKETRALGIEVG
                     DFISFDPRTVVTDTGFIKSRHLDDKVSAAMLLNLLRIYKKEKIELPVTTHFAFSVFEE
                     VGHGANSNIPAQVVEYLAVDMGAMGDDQQTNEYTVSICVKDASGPYHYDFRQHLVALA
                     KEQDIPFKLDIYPFYGSDASAAMSAGAEVKHALLGAGIESSHSYERTHIDSVVATERM
                     VDAYLKSALVD"
     gene            complement(4063..5388)
                     /gene="brnQ"
                     /locus_tag="VQU30_000891"
     CDS             complement(4063..5388)
                     /gene="brnQ"
                     /locus_tag="VQU30_000891"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006152071.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid transport system II
                     carrier protein"
                     /protein_id="HET2447024.1"
                     /translation="MAKKGTLTGLLLFGIFFGAGNLIFPPSLGALSGEHFLPAIAGFV
                     FSGVGIAVLTLIIGTLNPKGYIYEISTKIAPWFATLYLSVLYLSIGPFFATPRTATTA
                     YEVGISPLLSDANKGLGLIVFTVLYFAAAYLISLNPSKILDRIGRILTPVFAILIVIL
                     VVLGAIKYGGTSPQAASAAYQASAFGTGFLEGYNTLDALASVAFSVIAVQTLKQLGFS
                     SKKEYISTIWVVGIVVALAFSALYIGLGFLGNHFPVPAEAMKGGTPGVYILSQATQEI
                     FGSTAQLFLAAMVTVTCFTTTVGLIVSTAEFFNERFPQISYKVYATAFTLIGFAIANL
                     GLDAIIKYSIPVLVILYPITIAIVMIVIVNKFVALSKPGMQLTIAVVTVIAIASVLGS
                     SFKVEFLANLVSVLPFAKASLPWLVPAIVGILLSLVLPNKQESDVFEME"
     gene            complement(5559..5651)
                     /locus_tag="VQU30_000892"
     CDS             complement(5559..5651)
                     /locus_tag="VQU30_000892"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812032.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-like domain-containing protein"
                     /protein_id="HET2447025.1"
                     /translation="MRSARACQFLLEQGYNVINVQGGMLAFEEL"
     gene            complement(5694..5846)
                     /locus_tag="VQU30_000893"
     CDS             complement(5694..5846)
                     /locus_tag="VQU30_000893"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-like domain-containing protein"
                     /protein_id="HET2447026.1"
                     /translation="MKEIAFDAFYQLYQNDQLSLVDVREVDEFAALHLEGAHNLPLSQ
                     LADSYD"
     gene            complement(6006..6584)
                     /locus_tag="VQU30_000894"
     CDS             complement(6006..6584)
                     /locus_tag="VQU30_000894"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000078132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil-DNA glycosylase family protein"
                     /protein_id="HET2447027.1"
                     /translation="MSQIERIKQAIMADSQNASYTERGIEPLFAAPKTARINIIGQAP
                     GLKTQEAGLYWKDKSGDRLRDWLGVDEDTFYNSGYFAVLPMDFYFPGHGKSGDLPPCT
                     GFAEKWHPQLLQELPDIQLTLLIGQYAQAYYLQEKISGKVTERVKHYKDYLPAYFPLV
                     HPSPRNQIWMAKNPWFEAEVVPDLKKRIKTIL"
     gene            complement(6638..8038)
                     /gene="pepV"
                     /locus_tag="VQU30_000895"
     CDS             complement(6638..8038)
                     /gene="pepV"
                     /locus_tag="VQU30_000895"
                     /EC_number="3.4.13.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000125034.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dipeptidase PepV"
                     /protein_id="HET2447028.1"
                     /translation="MIAIDFTAEVEKRKEDLLADLFSLLEINSERDDSKADAQHPFGP
                     GPVKALEKFLEIADRDGYPTKNVDNYAGHFEFGDGEEVLGIFAHMDVVPAGSGWDTDP
                     YTPTIKDGRLYARGASDDKGPTTACYYGLKIIKELGLPTSKKVRFIVGTDEESGWADM
                     DYYFEHVGLAKPDFGFSPDAEFPIINGEKGNITEYLHFAGENTGAARLHSFTGGLREN
                     MVPESATAVVSGDLTDLQAKLDAFVAEHKLRGELQEEAGQYKVTIIGKSAHGAMPASG
                     VNGATYLALFLSQFGFAGPAKDYLDIAGKILLNDHEGENLKIAHVDEKMGALSMNAGV
                     FRFDETSADNTIALNIRYPKGTSPEQIKSILENLPVASVSLSEHGHTPHYVPMEDPLV
                     QTLLNVYEKQTGLKGHEQVIGGGTFGRLLERGVAYGAMFPDSIDTMHQANEFIALDDL
                     FRAAAIYAEAIYELIK"
     gene            complement(8051..8656)
                     /locus_tag="VQU30_000896"
     CDS             complement(8051..8656)
                     /locus_tag="VQU30_000896"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002924506.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitroreductase family protein"
                     /protein_id="HET2447029.1"
                     /translation="MKFLELNKKRHATKHFTDKPVDLKDVRTAIEIATLAPSAHNSQP
                     WKFVVVREKNAELAKLAYGSNFEQVSSAPVTIALFTDTDLAKRARKIARVGGANNFSE
                     EQLQYFMKNLPAEFARYNEQQVSDYLALNAGLVAMNLVLALTDQGIGSNIILGFDKSK
                     VNEVLEIEDRFRPELLITVGYTDDKLEPSYRLPVDEIIEKR"
     gene            8827..9627
                     /locus_tag="VQU30_000897"
     CDS             8827..9627
                     /locus_tag="VQU30_000897"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000714621.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter substrate-binding
                     protein"
                     /protein_id="HET2447030.1"
                     /translation="MKKFSLLLAILPFLVACGNQATPKETSAQKTIVLATAGDVPPFD
                     YEDKGNLTGFDIEVLKAVDEKLSDYEIQFQRTAWESIFPGLDSGHYQAAANNLSYTKE
                     RAEKYLYSLPISNNPLVLVSNKKNPLTSLDQIAGKTTQEDTGTSNAQFINNWNQKHTD
                     NPATINFSGEDIGKRILDLANGEFDFLVFDKVSVQKIIKDRGLDLSVVDLPSADSPSN
                     YIIFSSDQKEFKEQFDKALKELYQDGTLEKLSNTYLGGSYLPDQSQLQ"
     gene            complement(9809..10642)
                     /locus_tag="VQU30_000898"
     CDS             complement(9809..10642)
                     /locus_tag="VQU30_000898"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001015777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase family protein"
                     /protein_id="HET2447031.1"
                     /translation="MNHKIAILSDIHGNATALEAVIADAKTQGASEYWLMGDIFLPGS
                     GANDLVALLKELPITASVRGNWNDCVLEALDGQYGLEDPQEIQLMRMTQFLMERMDPA
                     TTVWLRSLPLLEKKEIAGLRFSISHNLPNKNYGGDLLVENDTEKFDQLLDAETDVAVY
                     GHVHKQLLRYGSQGQQIINPGSIGMPYFNWEALKNHRAQYAVIEVEDGELVNIQFRKV
                     AYDYEAELELAKSKGLPFIEMYEELRRDDNYQGHNLELLASLIEKHGYVEDVKNFFDF
                     L"
     gene            complement(10632..12479)
                     /gene="uvrC"
                     /locus_tag="VQU30_000899"
     CDS             complement(10632..12479)
                     /gene="uvrC"
                     /locus_tag="VQU30_000899"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001061148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit UvrC"
                     /protein_id="HET2447032.1"
                     /translation="MNNLIKSKLELLPTSPGCYIHKDKNGTIIYVGKAKNLRNRVRSY
                     FRGIHDTKTEALVSEIVDFEFIVTESNIEALLLEINLIKENKPKYNIMLKDDKSYPFI
                     KITNERYPRLIITRQVKKDGGLYFGPYPDVGAANEIKRLLDRIFPFRKCTNPPSKVCF
                     YYHIGQCMAHTICKKDEAYFKSMAQEVSDFLKGQDDKIIDDLKSKMAVAAQSMEFERA
                     AEYRDLIQAIGTLRTKQRVMAKDLQNRDVFGYYVDKGWMCVQVFFVRQGKLIERDVNL
                     FPYFNDPDEDFLTYVGQFYQEKSHLVPNEVLIPQDIDEEAVKALVDTKILKPQRGEKK
                     QLVNLAIKNARVSLEQKFNLLEKSVEKTQGAIENLGRLLQIPTPVRIESFDNSNIMGT
                     SPVSAMVVFVNGRPSKKDYRKYKIKTVVGPDDYASMREVIRRRYGRVQREALTPPDLI
                     VIDGGQGQVNIAKQVIQEELGLDIPIAGLQKNDKHQTHELLFGDPLEVVDLSRNSQEF
                     FLLQRIQDEVHRFAITFHRQLRSKNSFSSQLDGIDGLGPKRKQNLMRHFKSLTKIKEA
                     SVDEIVEVGVPRAVAEAVQRKLNPQETEILLQVAEERVDYQTEGNHNKP"
     gene            complement(12519..13220)
                     /locus_tag="VQU30_000900"
     CDS             complement(12519..13220)
                     /locus_tag="VQU30_000900"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001267193.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="matrixin family metalloprotease"
                     /protein_id="HET2447033.1"
                     /translation="MRWLFRLIGAFFSFVWRLFWRLVWIVVLLCVLAFGLLWYLNGDF
                     QGALKQAERSVKMGQQSIDQWEKTGQLPKLSQTDSHQHSEGRWAQASARIYLDPQMDS
                     RFQEAYLEAIQNWNQTGAFNFELVTESSKADITATEMNDGGTPVAGEAESQTNLLTGQ
                     FLSVTVRLNHYYLSNPYYGYSYERLVHTAEHELGHAIGLDHTDEKSVMQPAGSFYGIQ
                     EEDVANLRKIYETSE"
     gene            complement(13299..14531)
                     /gene="murN"
                     /locus_tag="VQU30_000901"
     CDS             complement(13299..14531)
                     /gene="murN"
                     /locus_tag="VQU30_000901"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001229509.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidoglycan bridge formation alanyltransferase
                     MurN"
                     /protein_id="HET2447034.1"
                     /translation="MALTTLTKEEFQTYSDQVSSRSFMQSVQMGDLLEKRGARIVYLA
                     LKQEGEIQVAALVYSLPMLGGLHMELNSGPIYTQQDALPVFYAELKEYAKQNGVLELL
                     VKPYETYQTFDSQGNPIDAEKKSIIQGLTDLGYQFDGLTTGYPGGEPDWLYYKDLTEL
                     TEKSLLKSFSKKGKPLVKKAETFGIRLKKLKREELSIFKNITKETSERREYSDKSLEY
                     YEHFYDTFGEQAEFLIASLNFSEYMSKLQGEQSKLEENLDKLRLDLSKNPHSEKKQNQ
                     LREYSSQFETFEVRKAEARDLIEKYGEEDIVLAGSLFVYMPQETTYLFSGSYTEFNKF
                     YAPALLQKYVMLESIKRGIPKYNFLGIQGIFDGSDGVLRFKQNFNGYIVRKAGTFRYH
                     PSPLKYKAIQLLKKIVGR"
     gene            complement(14536..15756)
                     /gene="murM"
                     /locus_tag="VQU30_000902"
     CDS             complement(14536..15756)
                     /gene="murM"
                     /locus_tag="VQU30_000902"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001819885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidoglycan bridge formation alanyltransferase
                     MurM"
                     /protein_id="HET2447035.1"
                     /translation="MYRYQIGIPTLEYDQFVKEHELANVLQSSAWEEVKSNWQHEKFG
                     VYREEKLLATASILIRTLPLGYKMFYIPRGPILDYGDKELLNFAIQSIKSYARSKRAV
                     FVTFDPSICLSQSLINQEKTEFPENLAIIDSLQQMGVRWSGKTEEMGDTIQPRIQAKI
                     YKENFEEDKLSKSTKQAIRTARNKGLEIQYGGLELLDSFSELMKKTEKRKEIHLRNEA
                     YYKKLLDNFKDKAYITLATLDVSKRSQELEEQLAKNRALEETFTESTRTSKVEAQKKE
                     KERLLEELTFLQEYIDVGQARVPLAATLSLEFGTTSVNIYAGMDDDFKRYNAPILTWY
                     ETARYAFERGMVWQNLGGVENSLNGGLYHFKEKFNPTIEEYLGEFTMPTHPLYPLLRL
                     ALDFRKTLRKKHRK"
     gene            complement(15868..16647)
                     /locus_tag="VQU30_000903"
     CDS             complement(15868..16647)
                     /locus_tag="VQU30_000903"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000290006.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="esterase family protein"
                     /protein_id="HET2447036.1"
                     /translation="MAVMKIEYYSQVLDMEWGVNVLYPDANRVEEPECEDIPVLYLLH
                     GMSGNHNSWLKRTNVERLLRGTNLIVVMPNTSNGWYTDTQYGFDYYTALAEELPQVLK
                     RFFPNMTSKREKTFIAGLSMGGYGCFKLALATNRFSHAASFSGALSFQNFSPESQNLG
                     SPAYWRGVFGEIRDWTTSPYSLESLAKKSDKKTKLWAWCGEQDFLYEANNLAVKNLKK
                     LGFDVTYSHSAGTHEWYYWEKQLEVFLTTLPIDFKLEERLT"
     gene            complement(16716..18377)
                     /locus_tag="VQU30_000904"
     CDS             complement(16716..18377)
                     /locus_tag="VQU30_000904"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease J"
                     /protein_id="HET2447037.1"
                     /translation="MSNISLTTLGGVRENGKNMYIAEIGESIFVLNVGLKYPENEQLG
                     VDVVIPNMDYLFENSDRIAGVFLTHGHADAIGALPYLLAEAKVPVFGSELTIELAKLF
                     VKGNDAVKKFNDFHVIDENTEIDFGGTVVSFFPTTYSVPESLGIVLKTSEGSIVYTGD
                     FKFDQTASESYATDFARLAEIGRDGVLALLSDSANADSNIQVASESEVRDEITQTIAD
                     WEGRIIVAAVSSNLSRIQQIFDAADKTGRRIVLTGFDIENIVRTAIRLKKLSLANEIL
                     LIKPKDMSRFEDHELIILETGRMGEPINGLRKMSIGRHRYVEIKDGDLVYIATAPSIA
                     KEAFVARVENMIYQAGGVVKLITQSLHVSGHGNVRDLQLMINLLQPKYLFPVQGEYRE
                     LDAHAKAAMAVGMLPEHIFIPKKGTTMAYENGDFVPAGSVSAGDILIDGNAIGDVGNV
                     VLRDRKILSEDGIFIVAITVNRREKKIVARARVHTRGFVYLKKSRDILRESSELINQT
                     VEDYLQGDDFDWADLKGKVRDNLTKYLFDQTKRRPAILPVVMEAK"
     gene            complement(18552..20774)
                     /gene="recJ"
                     /locus_tag="VQU30_000905"
     CDS             complement(18552..20774)
                     /gene="recJ"
                     /locus_tag="VQU30_000905"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001832038.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded-DNA-specific exonuclease RecJ"
                     /protein_id="HET2447038.1"
                     /translation="MITPTYEWQFALQVEDADFTKIAKKAGLGPEVARLLFERGIQDQ
                     ESLKKFLEPSLEDLHDAYLLHDMDKAVERIRQAIEEGENILVYGDYDADGMTSASIVK
                     ESLEQLGAECRVYLPNRFTDGYGPNASVYKYFIEQEGISLIVTVDNGVAGHEAIALAQ
                     SMGVDVIVTDHHSMPETLPDAYAIVHPEHPDADYPFKYLAGCGVAFKLACALLEEVQV
                     ELLDLVAIGTIADMVSLTDENRILVQYGLEMLGHTQRIGLQEMLDMAGIAANEVTEET
                     VGFQIAPRLNALGRLDDPNPAIDLLTGFDDEEAHEIALMIHQKNEERKEIVQSIYEEA
                     KTMVDPEKKVQVLAKEGWNPGVLGIVAGRLLEELGQTVIVLNIEDGRAKGSARSVEAV
                     DIFEALDPHRDLFIAFGGHAGAAGMTLEVEQLSDLSQVLEDYVREKGADAGGKNKLNL
                     DEELDLEALSLETVKSFERLAPFGMDNQKPIFYIKNFQVESARTMGAGNAHLKLKISK
                     GEASFEVVAFGQGRWATEFSQTKNLELAVKLSVNQWNGQTALQLMMVDARVEGVQLFN
                     IRGKNAVLPEGVPVLDFPGELPNLAASEAVVVKNIPEDITQLKTIFQEQHFSAVYFKN
                     DIDKTYYLTGYGTRDQFAKLYKTIYQFPEFDIRYKLKDLAAYLNIQQILLVKMIQVFE
                     ELGFVTIKDGVMTVNKEAPKREIGESQIYQNLKQTVKDQEMMALGTVQEIYDFLMEKE
                     "
     gene            21051..21809
                     /locus_tag="VQU30_000906"
                     /pseudo
     CDS             21051..21809
                     /locus_tag="VQU30_000906"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398007.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
     gene            21849..22613
                     /locus_tag="VQU30_000907"
     CDS             21849..22613
                     /locus_tag="VQU30_000907"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000624332.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transporter substrate-binding domain-containing
                     protein"
                     /protein_id="HET2447039.1"
                     /translation="MISLFGLAAAKPVQADTSIADIQKRGELVVGVKQDVPNFGYKDP
                     KTGTYSGIETDLAKMVADELKVKIRYVPVTAQTRGPLLDNEQVDMDIATFTITDERKK
                     LYNFTSPYYTDASGFLVNKSAKIKKIEDLNGKTIGVAQGSITQRLITELGKKKGLKFK
                     FVELGSYPELITSLHAHRIDAFSVDRSILSGYTSKRTELLDDSFKPSDYGIVTKKSNT
                     ELNDYLDNLVTKWSKDGSLQKLYDRYKLKPSSHTAD"
     gene            22626..23303
                     /locus_tag="VQU30_000908"
     CDS             22626..23303
                     /locus_tag="VQU30_000908"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517704.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HET2447040.1"
                     /translation="MIDLSSWTAYFQDFGQFFNGFLFTLALAIGSFILAMVLGIFFGA
                     MSTSKRPILRILAHIFVEFYQNTPLLVQFVIVFYGLPLISDHTIMIPIYWTAVLCMGL
                     YHGAYIAEVIRSGIQSIPSGQMEAALSQGFTYISAMRLIILPQTFRIILPPLTNQIVN
                     LIKNTSTVAIISGVDLMFVTKSWSALNGNYIPAFLGAALLYFALCFPVAQFGRKMEQA
                     NKKAYSL"
     gene            23313..23972
                     /locus_tag="VQU30_000909"
     CDS             23313..23972
                     /locus_tag="VQU30_000909"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000443867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HET2447041.1"
                     /translation="MESILEVLTPDNLVFIFKGFGLTLYISLIAIILSTIIGTVLAVM
                     RNGKNPVLRIISSIYIEFVRNVPNLLWIFTIFLVFKMKSTPAGITAFTLFTSAALAEI
                     IRGGLNTVDKGQYEAGMSQGFTSAQILYYIILPQAIRKMLPAIISQFVTVIKDTSLLY
                     SVIALQELFGASQILMGRYFEPEQVFSLCILIALIYFSFNLAISSLSHMLAKRWQQAA
                     E"
     gene            24267..25457
                     /locus_tag="VQU30_000910"
     CDS             24267..25457
                     /locus_tag="VQU30_000910"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000835812.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferric reductase-like transmembrane
                     domain-containing protein"
                     /protein_id="HET2447042.1"
                     /translation="MKSVKGLLFIIASFILTLLTWMNTSPQFMIPGLALTSLSLTFIL
                     ATRLPLLESWFHGLEKVYTVHKFTAFLSIILLIFHNFSMGGLWGSRLAAQFGNLAIYI
                     FASIILVAYLGKYIQYEAWRWIHRLVYLAYILGLFHIYMIMGNRLLTFNLLSFLVGSY
                     ALLGLLAGFYIIFLYQKISFPYLGKITHLKRLNHDTREIQIHLSRPFNYQSGQFAFLK
                     IFQEGFESAPHPFSISGGHGQTLYFTVKNSGDHTNNIYDNLQAGSKVTLDRAYGHMII
                     EEGRENQVWIAGGIGITPFISYIREHPILDKQVHFYYSFRGDENAVYLDLLRNYAQKN
                     PNFELHLIDSTKDGYLNFEQKEVPEHATVYMCGPISMMKALAKQIKKQNPKTELIYEG
                     FKFK"
     gene            complement(25778..26659)
                     /locus_tag="VQU30_000911"
     CDS             complement(25778..26659)
                     /locus_tag="VQU30_000911"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001018994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fructose-bisphosphate aldolase"
                     /protein_id="HET2447043.1"
                     /translation="MAIVSAEKFVQAARDNGYAVGGFNTNNLEWTQAILRAAEAKKAP
                     VLIQTSMGAAKYMGGYKVARNLIANLVESMGITVPVAIHLDHGHYEDALECIEVGYTS
                     IMFDGSHLPVEENLKLAKEVVEKAHAKGISVEAEVGTIGGEEDGIIGKGELAPIEDAK
                     AMVETGIDFLAAGIGNIHGPYPVNWEGLDLDHLQKLTEALPGFPIVLHGGSGIPDEQI
                     QAAIKLGVAKVNVNTECQIAFANATRKFARDYEANEAEYDKKKLFDPRKFLADGVKAI
                     QASVEERIDVFGSEGKA"
     gene            complement(26800..28128)
                     /gene="vncS"
                     /locus_tag="VQU30_000912"
     CDS             complement(26800..28128)
                     /gene="vncS"
                     /locus_tag="VQU30_000912"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000831335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase VncS"
                     /protein_id="HET2447044.1"
                     /translation="MKRTGLFAKIFIYTFSIFSVLVICLHLAIYFLFPSTYLSHRQET
                     IGQKATAIAQSLEGKDRQSIEQVLDLYSQTSDIKGTVKGEMTEDKLEVKDSLPLDTDR
                     QTTSLFIEEREVKTQDGATMILQFLASMDLQKEAEQISLQFLPYTLLASFLISLLVAY
                     IYARTIVAPILEIKRVTRRMMDLDSQVRLRVDSKDEIGNLKEQINSLYQHLLTVIADL
                     HEKNEAILQLEKMKVEFLRGASHELKTPLASLKILIENMRENIGRYKDRDQYLGVALG
                     IVDELNHHVLQILSLSSVQELRDDRETIDLLQMTQNLVKDYALLAKERELQIDNSLTH
                     QQAYLNPSVMKLILSNLISNAIKHSVPGGLVRIGEREGELFIENSCSSEEQEKLAQSF
                     SDNASRKVKGSGMGLFVVKSLLEHEKLAYRFEMEENRLTFFIDFPKVVQD"
     gene            complement(28125..28781)
                     /gene="vncR"
                     /locus_tag="VQU30_000913"
     CDS             complement(28125..28781)
                     /gene="vncR"
                     /locus_tag="VQU30_000913"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor VncR"
                     /protein_id="HET2447045.1"
                     /translation="MKILIVEDEEMIREGVSDYLTDCGYETIEAADGQEALEQFSSYE
                     VALVLLDIQMPKLNGLEVLAEIRKTSQVPVLMLTAFQDEEYKMSAFASLADGYLEKPF
                     SLSLLKVRVDAIFKRYYDTGRIFSYKDTKVDFESYSASIAGQEVPINAKELEILDYLV
                     KNEGRALTRSQIIDAVWKATDEVPFDRVIDVYIKELRKKLDLDCILTVRNVGYKLERK
                     "
     gene            complement(28830..28913)
                     /gene="pep27"
                     /locus_tag="VQU30_000914"
     CDS             complement(28830..28913)
                     /gene="pep27"
                     /locus_tag="VQU30_000914"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_198524447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative autolysis signal peptide Pep27"
                     /protein_id="HET2447046.1"
                     /translation="MRKEFHNVLSSGQLLADKRPARDYNRK"
     gene            complement(29093..30472)
                     /gene="vex3"
                     /locus_tag="VQU30_000915"
     CDS             complement(29093..30472)
                     /gene="vex3"
                     /locus_tag="VQU30_000915"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease subunit Vex3"
                     /protein_id="HET2447047.1"
                     /translation="MLHNAFAYVTRKFFKSIVIFLIILLMASLSLVGLSIKGATAKAS
                     QETFKNITNSFSMQINRRVNQGTPRGAGNIKGEDIKKITENKAIESYVKRINAIGDLT
                     GYDLIETPETKKNLTADRAKRFGSSLMITGVNDSSKEDKFVSGSYKLVEGEHLTNDDK
                     DKILLHKDLAAKHGWKVGDKVKLDSNIYDADNEKGAKETVEVTIKGLFDGHNKSAVTY
                     SQELYENTAITDIHTAAKLYGYTEDTAIYGDATFFVTADKNLDDVMKELNGISGINWK
                     SYTLVKSSSNYPALEQSISGMYKMANLLFWGSLSFSVLLLALLLSLWINARRKEVGIL
                     LSIGLKQASILGQFITESILIAIPALVSAYFLANYTARAIGNTVLANVTSGVAKQASK
                     AAQASNLGGGAEVDGFSKTLSSLDISIQTSDFIIIFVLALVLVVLVMALASSNLLRKQ
                     PKELLLDGE"
     gene            complement(30524..31171)
                     /gene="vex2"
                     /locus_tag="VQU30_000916"
     CDS             complement(30524..31171)
                     /gene="vex2"
                     /locus_tag="VQU30_000916"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000173730.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding subunit Vex2"
                     /protein_id="HET2447048.1"
                     /translation="MTLLQLQDVTYRYKNTAEAVLYQIDYNFEPGKFYSIIGESGAGK
                     STLLSLLAGLDSPVEGSILFQGEDIRKKGYSYHRMHHISLVFQNYNLIDYLSPLENIR
                     LVNKKASKDTLLELGLDESQIKRNVLQLSGGQQQRVAIARSLVSEAPVILADEPTGNL
                     DPKTAGDIVELLKSLAQKTGKCVIVVTHSKEVAQASDITLELKDKKLTETRNTSK"
     gene            complement(31184..32461)
                     /locus_tag="VQU30_000917"
     CDS             complement(31184..32461)
                     /locus_tag="VQU30_000917"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001068247.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HET2447049.1"
                     /translation="MNPIQRSWAYVSRKRLRSFILFLILLVLLAGISACLTLMKSNKT
                     VESNLYKSLNTSFSIKKIENGQTFKLSDLASVSKIKGLENVSPELETVAKLKDKEAVT
                     GEQSVERDDLSAADNNLVSLTALEDSSKDVTFTSSAFNLKEGRHLQKGDSKKILIHEE
                     LAKKNGLSLHDKIGLDAGQSESGKGQTVEFEIIGIFSGKKQEKFTGLSSDFSENQVFT
                     DYESSQTLLGNSEAQVSAARFYVENPKEMDGLMKQVENLALENQGYQVEKENKAFEQI
                     KDSVATFQTFLTIFLYGMLIAGAGALILVLSLWLRERVYEVGILLALGKGKSSIFLQF
                     CLEVVLVSLGALLPAFVAGNGITSYLLQTLLASGDQASLQDTLAKASSLSTSILSFAE
                     SYVFLVLLSCLSVALCFLFLFRKSPKEILSSIS"
BASE COUNT         9183 a         7453 c         6047 g         9848 t
ORIGIN      
        1 attcgtccta ctcttatttc attttactat aattgatagt ggtcgcccca gccagatacc
       61 ttatccgcta tataggcctt attatcatgt tcctgttcgt agagccacga tttcgctatc
      121 ccttcctctg acgattctta tttcctgcgt cagacttggg aatcgctatt gggttcaccg
      181 gtagcaggtg cccaccgagg acttacacct cagatatacg acatgcccgt cgtacatcaa
      241 aaaaagttga gacatagcgt cttcaacttt tttacattac tttaactact gattaaagtg
      301 agtttacgtc aactttgata ccaacacctt gagtagttgt gatagtcaag tttgttacgt
      361 aagttccttt agctgtagct ggttttgctt tttggattgt ttcgttgaaa gctttaaagt
      421 tttcaaccaa tttttcagct tcaaatgata ctttaccgat gattgcttga acgttacctg
      481 cacggtcagc acggtaagtg attttaccac ctttagactc ttcaactgct ttagcaacat
      541 ccattgttac agtaccagtt ttagggtttg gcatcaagtt acgtggtcca aggacacgtc
      601 caagacgtcc aacaagaccc atcatatcag gtgtagcgat aactacgtcg aagtccaacc
      661 aaccgtcgtt gattttagca acaaggtcat cttcaccaac aaagtctgca ccagcagctt
      721 ttgcttcttc agcttttgca ccacgtgcga aaacaagaac gcgtgaagtt ttaccagtac
      781 cgtttggcaa taccattgct ccacggattt gttgatcagc ttttttaacg tcgatgttca
      841 agttgtaagc aacttctaca gttgcgtcaa attttgcaaa gtttgtttct tttgcaagtg
      901 ctacagcttc ttctacgctg tatgcttttg tgctgtcgat tttctcaaga gcagcacgaa
      961 gttgtttgct ttttttagcc attttctatt ctccttgtaa gtggttcaat cgattttcat
     1021 ctcccacgtc acttctcgaa atgatgaagt cttgcgggtt ttcagtctat tagattcttt
     1081 tcctacggcc ttaagctccc ttgctgtacc caagtacaag catcagtcac ttgcctagta
     1141 tgaaaagcaa ctaatagact gctgtgagat tttctactgt gttattgatt agtcaataac
     1201 agtgaatccc atagaacgag cagtaccttc gatcatacgc actgcagact ctacgtttgc
     1261 tgcgttcaaa tctggcatct tagtttctgc aatttcttgt acttgtgcac gagtaactgt
     1321 agcaacttta gttttattag gtgtacctga tcctttttca acacctgcag cttttttcaa
     1381 aagaacagca gctggtggtg ttttcgtaac gaaagtaaat gatttatctt cgtaaactga
     1441 gataacaact ggaatgatca taccagcttg gtcagctgta cgagcgttga actcttttgt
     1501 gaatcccatg atgttgatac cagcttgacc aagagcaggt ccaaccggtg gagctggtgt
     1561 agctttacca gcagggattt gcaattttac aagtttttcg acttttttag ccatttttaa
     1621 atcctccttt gtggttttgg cggtaattag agatttttac ctcccacaag tatgtttttc
     1681 acatacccat ctattataca ctatttatct ggaattgcaa gagaaaagtt tattttttaa
     1741 tcgacgtaat ctccaccttc aaagccgaaa tactcttcca aactgaggcc actagctgca
     1801 atctctttag cctcttttcc gacataacga aggtgccatt cctcagccat atagcctgtt
     1861 tccttttcct tacctttgag ataacgtaca acaaagccat aatcagccgc atgatccaag
     1921 agccattggg ccgctttttc ttctgtcacc aaatcaccat ttgtcccaat cacatcaaag
     1981 gctaaacctg tctggtgctc gctatagcca ggacgggcag aataacggtc ggcagcttct
     2041 ttcccatctt gattgacata atcttgatag agcttggtct gagtttcata acttctaaag
     2101 ccactgtaat gatcgctaat ggggaaacct gcctcttgca tagctttgat gagcttgacc
     2161 aactcagcct tggctgttgg attttcccct ggattgtagt cttttgacaa tggatagtgt
     2221 ttgttggcta cgatgatttc atcgtatttc ccttgaatgc tgtaatagtc tcctttgtta
     2281 accacttctg cttttttctg ggcagctcct tgagacttac ttcctactgt tccatcagct
     2341 ttagcagttt gctctgtctt agctgctcca tcttcatttt ttgctttttc ttgtgaacaa
     2401 gctgctagac tcaaggctag caaggctgtc aagacaaggt atcttttttt catctttact
     2461 cctttatttc taatagttta tctacttctg atgataaacg ttcgactaat cttttaatct
     2521 catcaggttt tgattggcag atttctgctg tcatttcttc aaagggaatc caccatactg
     2581 gaccacgtcc attgaggcca taaccattca tatcacctct tcgtctagga aacagatgcc
     2641 aatggagatg agcatcgcca tttcctagta gttcgatatt cattttctca gcagcaaagg
     2701 ccttggcaac tgcctcttgg accacactca tttcttctag aaaacgtatt ctagttttct
     2761 tttctaaatg atgcaattcg ctgacatgtt ccttggctag aaagagacta tagcctgcaa
     2821 aatactggtg gtctccaatc acaagatagc ctgtttccaa ctctttgaca aaatagggat
     2881 tttctccctt cttgatgagc tcaattctct ggcaaatcaa acacatatta gtctaccaat
     2941 gcactcttaa gataggcatc gaccattcgt tctgttgcga ccaccgagtc aatatgagtg
     3001 cgctcataag aatgactaga ctcgataccc gcaccaagaa gggcatgctt gacctctgcc
     3061 cctgcagaca tagccgctga agcatccgaa ccataaaatg gatagatgtc cagcttaaaa
     3121 ggaatatctt gctctttagc caaggcaacc aagtgttgac ggaagtcata gtgataagga
     3181 cctgaggcat ccttgacaca gatagatact gtgtactcat ttgtctgctg gtcatctccc
     3241 atagctccca tatccacagc cagatattct actacctgag caggaatgtt agaattagca
     3301 ccatgtccta cttcttcaaa aactgaaaaa gcaaaatgag ttgttactgg caattcaatc
     3361 ttctctttct tataaatacg aagcaggttg agcaacatcg ctgcgctgac cttatcatcc
     3421 aaatgacgag acttgataaa acctgtatca gtcacaacag ttcgtggatc gaagctgata
     3481 aaatcaccga cctcaatccc aagagcacga gtttcttttt cattgcttac ttttacatcc
     3541 aaacgcactt ccatattgtc ctgcgtgcgt tctgcagttc ctgcatcctt gtagacatgg
     3601 caagaagttt ggtggatgag gatggttcct aatacctttt gacctgtgct agccacatga
     3661 acggtacagt tttcaccttc aatcatgttc caaggaaaac caccgatacg gtccaattta
     3721 agacgaccat ctggtttgac agcacgaaca atagcaccca gtgtgtccac atgggcagtc
     3781 acatagcgat gttgctcatc attttgacct ttgatggtca cattgacacc acccttggct
     3841 gtgcgaactg gctggtaacc aaaaccttct agagtcttga ctaaataatt cgaaatttca
     3901 cgagtgaagc ccgttggcga tgcgatggct gtcagttctt tgatatattc tactgtttga
     3961 ttcatttctt cacctctttc gctacctatt ataacacatt tatcatcgga taaaaaaaga
     4021 aaatcactcc tgtagacttg gctacaaaag tgatttaagt gattattcca tttcaaaaac
     4081 atcgctttct tgcttgtttg gtagaaccaa tgagagcaag attccaacaa tggctggcac
     4141 caaccatggg agagatgcct tggcaaaagg aagaacgcta acaagatttg caagaaactc
     4201 aaccttaaac gagcttccta gtacgcttgc aatggcaata actgtaacca cagcaattgt
     4261 caactgcata cctggttttg aaagggcaac aaatttgttg acaatgacaa tcataacgat
     4321 agcaatcgtg attgggtaca agataaccag tactggaatt gagtacttga taatcgcatc
     4381 aagacccaaa ttggcaatag caaatccaat caaggtaaag gctgtcgcat aaaccttgta
     4441 gctgatttgt gggaagcgct cattaaagaa ctcagctgtt gacacaatca aaccaacagt
     4501 cgttgtgaag caggttacgg taaccatagc tgcaaggaag agttgagctg ttgagccaaa
     4561 gatttcttga gtggcttgtg acaagatgta aacacctggt gttccaccct tcatcgcttc
     4621 agctggtact gggaaatgat ttccaagaaa acctaaaccg atgtaaagag cgctgaaggc
     4681 aagggcaaca acgataccaa caacccaaat agttgaaatg tattctttct tacttgaaaa
     4741 tccaagttgt ttcaaggttt gaactgcgat tacgctaaag gccactgagg caagggcgtc
     4801 caaggtatta taaccttcta ggaaacctgt accaaaggca gaagcttgat aagcagctga
     4861 agcagcttga ggacttgttc caccatattt gatagctccc agaacgacca agataacaat
     4921 caaaattgca aagactggcg ttaaaatacg tccaatgcgg tctaagattt ttgatggatt
     4981 aagcgaaatc aaataggctg ccgcaaaata cagaaccgta aatacaatca agccaagtcc
     5041 tttatttgca tccgacaaaa gggggctaat ccctacttcg taagctgttg tagcagtacg
     5101 tggggtagca aagaatggac cgattgacaa gtaaagaact gagaggtaaa gagtcgcaaa
     5161 ccaaggcgct atcttcgttg aaatctcgta gatatatcct ttaggattta gcgttccaat
     5221 aataagggtc aagacggcga taccaacgcc tgaaaagaca aaacctgcga tggcaggaag
     5281 aaaatgttct ccagatagag cacctagaga aggcggaaaa atcaagttcc ccgcaccaaa
     5341 aaatattcca aacaggagca aacctgttag ggtacctttt ttagccataa aaatctcctt
     5401 catatttata aaatactgat ctagtatacc acgattagga gtctgaaaaa agcatcacga
     5461 ggcaaatatt aaatgttttc aattttctta aaaataagaa ttatctaaaa ataaaactct
     5521 cctacccagt ccacaccaag taggagaaat gcaaaatttt aaagttcttc aaaggctaac
     5581 atgccaccct ggacattgat aacattataa ccttgttcta ataggaattg gcaagcacgc
     5641 gccgatctca ttccagattt gcaaataata taatgcaagc gatctttgtc caattaatca
     5701 taactatcag ccaattgact aagcggtagg ttgtgggcac cttctaaatg aagagctgca
     5761 aactcatcca cttctctcac atccactaga gaaagctggt cgttttggta aagctggtaa
     5821 aatgcgtcaa aggctatttc tttcattctt tttcttctaa tactcttcga aaatctcttc
     5881 aaaccacgtc agcgtcgcct taccgtgcgt atgttaccga cttcgtcagt tttatctgca
     5941 acttcaaagc tgtactttga gcagcctacg actagcttcc tagtttgctc tttgattttc
     6001 attgactata aaatggtttt aattcttttt ttcaaatctg gcactacttc tgcctcaaac
     6061 caaggatttt tggccatcca gatttgattt cgtggtgatg ggtgaactag cggaaaatag
     6121 gctggcagat agtctttata gtgtttcacc ctctccgtta ccttcccact gattttctcc
     6181 tgtaaatagt aggcttgggc atattgccca atcaagaggg ttaactgaat atcaggcaat
     6241 tcctgtaaga gctgcggatg ccatttttct gcaaaacctg tacaaggcgg aagatcaccc
     6301 gacttgccat gtcctggaaa gtagaaatcc ataggcaaaa cagcaaaata acctgaattg
     6361 taaaaggtat cttcatccac acctagccag tcccgcaaac ggtcaccact tttatctttc
     6421 cagtaaaggc ctgcttcttg agttttaagt cccggagcct gaccgatgat attgatgcga
     6481 gcagtttttg gcgctgcaaa gagaggctca atgccacgct ctgtatagct ggcattctgc
     6541 gaatccgcca tgatagcctg tttgattctt tcgatttgag acatctactt tccctccaaa
     6601 aagaagtcca agcataagat ctcagacttc tatcgtttta tttgatcaat tcgtaaatag
     6661 cttcggcata aattgctgct gctcggaaga gatcgtccaa ggcaataaat tcattggctt
     6721 ggtgcatggt atcaattgag tctgggaaca tagcaccata ggcaactccg cgctctaaca
     6781 agcgaccaaa ggttccacca ccgatgactt gttcatgacc tttaaggcct gtttgttttt
     6841 catagacatt caacaaggtt tgcacaagtg gatcttccat tggcacatag tgaggggtat
     6901 gaccatgttc tgatagactg acagaagcaa ctggcaagtt ttctaggatt gacttgattt
     6961 gttctggact tgttcctttt ggatagcgga tgttaagggc aatggtatta tcagcacttg
     7021 tttcatcgaa gcggaagacg ccggcattca tagaaagagc acccatcttt tcatccacat
     7081 gagcaatctt gagattttca ccctcatgat cgttcaagag aattttacct gcgatgtcaa
     7141 ggtagtcttt ggctggacca gcaaagccaa actggctgag gaagagggca aggtaagttg
     7201 cgccattgac acctgaagca ggcatagcac cgtgggctga tttaccaatg atcgtcacct
     7261 tgtattggcc agcttcttct tggagttctc ctctaagttt gtgttctgca acaaaggcat
     7321 ctagtttagc ttgcaagtct gtcaagtcac ctgaaacgac tgctgttgct gattctggta
     7381 ccatattttc acgtaaacca cctgtaaagc tgtgaagacg ggctgcacct gtattttcac
     7441 ctgcaaagtg gaggtattcc gtgatgtttc ctttttcacc attgatgatt ggaaattcag
     7501 catctggtga gaaaccaaag tctggcttgg cgagtcctac gtgctcgaag tagtagtcca
     7561 tatctgccca gcctgattct tcgtctgttc caacgatgaa gcgaactttc ttagaagttg
     7621 gaaggcccaa ttctttgatg attttcaaac catagtagca agctgttgta ggtcccttgt
     7681 catctgaagc accacgcgca taaaggcgac catctttgat agttggtgtg taagggtctg
     7741 tgtcccaacc gctaccagct ggaaccacgt ccatatgggc aaagattccg agaacttctt
     7801 ctccatcacc aaactcaaaa tgtcctgcat agttatcaac atttttagtt ggataaccat
     7861 cacggtctgc gatttcaagg aatttttcca aggcttttac tggaccaggt ccaaatggat
     7921 gttgggcatc agccttgcta tcatcacgtt ctgagttgat ttccaaaagg ctaaacaagt
     7981 cagccaagag gtcttctttg cgtttttcta cttctgctgt aaaatcaatt gctatcattt
     8041 tttcttcttc ctatcttttt tcgatgattt catctactgg caagcggtag cttggttcca
     8101 atttgtcgtc tgtgtaaccc actgtgatca agagttctgg gcggaaacgg tcttcaattt
     8161 ccaaaacctc attgactttt gatttgtcaa aaccaaggat aatattggaa ccaattcctt
     8221 ggtctgtaag agcgagaacc aagttcatag caaccaaacc tgcattgagt gctaggtagt
     8281 cgctgacttg ttgttcattg tagcgtgcaa attcagctgg caaatttttc atgaagtatt
     8341 gaagttgttc ttctgagaaa ttgttagcac caccaactcg ggcaatctta cgagcgcgtt
     8401 tggcaaggtc tgtatctgta aatagggcaa tggttacagg tgctgatgat acctgctcaa
     8461 agtttgaacc ataagccaac tttgccagtt cagcattttt ctcacgaaca actacaaatt
     8521 tccaaggctg gctgttgtgg gcgcttggcg ccaaggttgc aatttcgata gccgtacgca
     8581 catcttttag atcaacaggc ttatcagtga aatgcttggt cgcatgacgt tttttattta
     8641 attcaagaaa tttcataatc gatttccttt tctaattcta ctgcttccat tctaccataa
     8701 tttgaaagag cttgcaggga tttttcatga ttaagttttt ctatcacaga cataaaagat
     8761 atatattggt ttatcaggaa agtttctgat aaactagcaa gtactttaca tttgaatgga
     8821 gacagtatga aaaaatttag cctattacta gctatcctac catttttggt tgcctgtggg
     8881 aatcaagcta cacccaaaga gactagcgct caaaagacaa tcgtccttgc tacagctggc
     8941 gacgtgccac catttgacta cgaagataaa ggcaatctga caggcttcga tatcgaagtt
     9001 ctaaaggcag tagatgaaaa actcagcgac tacgagattc aatttcaaag aaccgcctgg
     9061 gaaagtatct tcccaggact tgattctggt cactatcagg ctgcggccaa taatttgagt
     9121 tacacaaaag agcgtgctga aaaatacctt tactcgcttc cgatttccaa caatcccctc
     9181 gtccttgtca gcaacaagaa aaatcctttg acttctcttg accagatcgc tggtaaaaca
     9241 acacaagagg ataccggaac ttctaacgct caattcatca ataactggaa tcagaaacac
     9301 actgataatc ccgctacaat taatttttct ggtgaggata ttggtaaacg aatcctagac
     9361 cttgctaacg gagagtttga tttcctagtt tttgacaagg tatccgttca aaagattatc
     9421 aaggaccgtg gtttagacct ctcagtcgtt gatttacctt ctgcagatag ccccagcaat
     9481 tatatcattt tctcaagcga ccaaaaagag tttaaagagc aatttgataa agcactcaaa
     9541 gaactctatc aagacggaac ccttgaaaaa ctcagcaata cctatctagg tggttcttac
     9601 ctcccagatc aatctcagtt acaataacac tcttcgaaaa tctcttcaaa ccacgtcagc
     9661 tttatctgca acctcaaagc tgtgctttga gcaacctacg gctagcttcc tagtttgctc
     9721 tttgattttc attgagtata agatatacta aaagcgattg gaccagccaa tcgctttttt
     9781 agtttgcatt ggctatttta ggaaactctt acaaaaaatc aaaaaaattc ttcacatcct
     9841 ctacataccc atgcttttct attaagctgg ctaaaagttc cagattgtgc ccctgatagt
     9901 tatcgtcacg acgcagttct tcatacattt caataaaggg aagccccttg gacttggcca
     9961 attctaactc agcctcgtaa tcataagcaa ctttacgaaa ttggatattg accaattccc
    10021 catcttcaac ttctatcacg gcatactggg cacggtgatt ttttaacgcc tcccaattaa
    10081 aatagggcat gccaatcgac cctggattga tgatttgttg cccttgactt ccataacgaa
    10141 gcaactgctt gtgaacatga ccataaactg ccacgtccgt ttccgcatct agcagttggt
    10201 caaatttctc tgtatcattc tcaactagca agtcaccacc atagttctta tttggcaaat
    10261 tatgagagat agaaaagcgc agtccagcaa tttctttctt ttccagcaaa ggcaagcttc
    10321 gtagccagac agtcgttgca ggatccattc gctccatcaa aaactgagtc attcgcatga
    10381 gctggatttc ctgtgggtct tctaagccat attgcccatc taaagcctca aggacacaat
    10441 cattccaatt gcctcgaaca cttgccgtga taggaagttc ctttaacaga gcgaccaagt
    10501 catttgcacc tgaaccaggg aggaaaatgt ctcccatgag ccaatattca ctggctcctt
    10561 gagttttagc atctgcaatc actgcttcta gcgccgtcgc attgccatga atatctgata
    10621 aaattgcgat tttatggttt attgtggttt ccttccgttt ggtaatctac tctttcttcc
    10681 gccacttgaa gcaagatttc tgtttcctgc gggttcaact ttctttgcac agcctctgct
    10741 actgctcttg gtactccaac ttcgacaatc tcatccacac tggcttcctt gattttggtc
    10801 agagacttga agtgcctcat gagattttgc ttgcgtttag gtcccagacc atcaatccca
    10861 tccaattgag atgagaaaga atttttggag cgcagttggc ggtggaaggt aatggcaaag
    10921 cggtggacct catcttgaat gcgttggagg aggaaaaatt cctgagaatt gcgagacaag
    10981 tccaccactt ccagcggatc tccaaagagc aattcatggg tttggtgctt atcattcttt
    11041 tgcagacctg caattggaat atccaagccc agttcttctt ggatgacttg cttagcaata
    11101 ttgacttgac cttgcccccc atcaatcaca atcaaatctg gaggagtcaa agcctcacgc
    11161 tgtactcgac catagcgtct tcgaatgact tctctcatac tagcatagtc gtccggccca
    11221 acaacggttt ttatcttgta cttacggtaa tcttttttac ttggcctgcc gttaacaaag
    11281 accaccatgg ctgaaacagg actggtcccc atgatgttgg agttatcgaa ggactcgatg
    11341 cgaactggag tcggaatttg gagcaaacgt cctagatttt caatagctcc ttgggtcttt
    11401 tcgactgatt tttctagcag gttaaatttc tgctccagac taacacgtgc attttttatg
    11461 gctagattga ccagctgttt tttctctcca cgttggggtt tgagaatctt ggtatccacc
    11521 aaagccttga cagcttcttc gtcaatatcc tgcggaatca gtacctcatt gggaactagg
    11581 tgagattttt cttgatagaa ttgtcccaca taggtcaaga aatcctcatc tggatcattg
    11641 aagtagggga agagattgac atcgcgctcg atgagcttgc cctgacgaac aaagaaaacc
    11701 tgcacacaca tccagccctt atccacatag tagccaaaga catcgcgatt ttggagatcc
    11761 ttagccatga cccgttgctt ggttcgaagc gttccaatag cctgaatcag gtcacggtat
    11821 tccgccgcac gttcaaactc catactttgt gctgctactg ccattttact cttgagatca
    11881 tcgatgattt tgtcatcctg acctttcaga aaatcagaca cctcctgagc catagacttg
    11941 aaataagcct catccttctt acagatggtg tgggccatac actggccgat atggtaataa
    12001 aaacagacct tagagggcgg gttggtacat tttcgaaaag ggaaaatcct atctagaagt
    12061 cgcttgattt cattggctgc ccccacatct ggataagggc caaaataaag accaccgtcc
    12121 tttttgacct gacgagtaat gataagccgt ggatagcgct cattggtgat tttgatgaaa
    12181 ggataggact tgtcatcctt gagcatgata ttgtacttgg gcttattttc cttgatcaag
    12241 ttgatttcca gcagaagcgc ctcaatattg gactcagtga cgataaattc aaaatccaca
    12301 atttcagaca ccagagcctc tgtcttggta tcatgaattc cacgaaaata ggaccgtact
    12361 cgattacgca gatttttagc ctttcctaca tagataatgg tgccattttt atccttatga
    12421 atgtagcaac cagggctggt cggcaagagc tctagttttg atttaatcaa gttgttcata
    12481 gttccattat agcaaaaaaa gtagggaaag atagtaccct actcactagt ctcatatatt
    12541 tttcggaggt ttgcaacatc ctcttcctgg ataccataaa aggaacctgc tggttgcatg
    12601 acagacttct catctgtatg gtccaagcca atcgcatgac ctaactcatg ttctgccgta
    12661 tggacaaggc gttcatagga gtagccatag tatggattgg acaaataata atgattcaac
    12721 cgcaccgtta cggacaagaa ttgccctgtt aagagattag tttgactttc cgcctctcct
    12781 gccacaggag tgcctccgtc gttcatctcc gtagccgtaa tatccgcctt actagactca
    12841 gtcacgagtt caaagttaaa agcaccagtt tgattccagt tctggattgc ttctaaataa
    12901 gcctcttgaa agcgtgaatc catctgcgga tccaggtaaa tacgagcaga ggcctgtgcc
    12961 caccttcctt cagaatgctg gtgactatct gtctggctta acttaggcag ttgccctgtt
    13021 ttctcccatt ggtcaatact ttgttgaccc atttttactg accgttctgc ttgctttagc
    13081 gctccttgaa aatccccgtt cagataccag agaagtccga aagcaagcac acataagagc
    13141 acaactatcc aaaccagacg ccaaaacaaa cgccacacaa aagaaaagaa agcccctatc
    13201 aaacgaaaaa gccagcgcat gtctctccac ctttctagca aataagaatt attttactaa
    13261 aagaagctaa aagaaatcta aatactgact ttttcatctt aacgtcctac tatttttttg
    13321 agtaactgga tagctttgta ttttaaaggc gatggatggt aacggaaagt acctgctttg
    13381 cgtacaatat agccattaaa attctgttta aaacgcaaaa caccatcact tccatcaaaa
    13441 atcccttgaa tgcctaggaa gttgtattta ggtattccac gttttatgct ttccaacata
    13501 acatattttt gaagcagtgc aggggcatag aacttattaa actcagtgta ggaaccacta
    13561 aagagataag tcgtttcctg aggcatataa acaaataaac tcccagctaa aacaatatct
    13621 tcttctccat atttttcaat caagtctcgc gcttctgctt ttcgaacttc aaacgtttca
    13681 aattgactag aatattctct cagttgattt tgttttttct cagaatgagg atttttactc
    13741 aaatcaagtc gcaacttgtc caagttttct tctagtttac tttgttcacc ttgcaatttg
    13801 ctcatatact ccgaaaaatt caagcttgct atgagaaact ccgcttgttc tccaaaagta
    13861 tcataaaaat gctcataata ttctaaactt ttatcactat attctctacg ttcagaggtt
    13921 tcttttgtta tattcttaaa aatcgatagt tcttcacgtt ttaacttttt caaccgaatg
    13981 ccaaaggttt cagccttttt caccaagggt ttaccctttt tgctaaaact tttaagcaaa
    14041 ctcttttcag ttaattcagt taaatcttta tagtataacc aatctggttc tccacctggg
    14101 taacctgttg ttaagccatc aaattgataa cctaaatcag tcaaaccttg aataatactt
    14161 tttttctcag catctattgg attaccttgg ctatcaaaag tttgataagt ttcataaggt
    14221 tttacaagca actctaatac accattttgc ttggcatatt cttttaactc tgcataaaaa
    14281 actggaagag catcttgttg ggtataaatc ggccccgaat tgagttccat atgcagacca
    14341 cccagcatgg gcaagctata aaccagagct gcaacttgaa tttctccttc ttgtttcaaa
    14401 gcaagataaa caattcgagc ccctcttttt tctagcaaat cccccatctg gacagattgc
    14461 ataaaggaac gagaagaaac ctgatcagaa taagtctgaa actcttcttt cgtgagtgtt
    14521 gttagtgcca tatacttact ttctatgttt ttttcttaat gttttacgga aatcaagagc
    14581 aagtcttaac agaggataga gaggatgagt gggcattgta aattcaccca agtattcttc
    14641 aatcgttgga ttaaattttt ccttaaaatg ataaagtcca ccattgagag agttttcaac
    14701 accacctaaa ttttgccaga ccatacctcg ctcaaaggca tagcgagccg tttcatacca
    14761 tgttaaaatt ggtgcattgt aacgtttaaa atcatcatcc ataccagcat atatattgac
    14821 agaggtagta ccaaattcca aactcaaagt agccgctaaa ggaactctcg cttgacctac
    14881 atctatatat tcctgcaaga aggtcaattc ctctaacaaa cgttcttttt ccttcttctg
    14941 cgcttctact tttgaagttc gagtcgactc agtaaaggtc tcttccaagg ctctattttt
    15001 cgctaactgt tcttctaact cttgcgaacg tttagaaaca tccaaggtgg ccaaggtgat
    15061 ataggccttg tccttaaaat tatctaacaa ttttttataa taggcttcat tcctcaaatg
    15121 aatctctttt cgcttctcag tttttttcat caactccgaa aatgaatcta atagttccag
    15181 tccaccatat tgaatctcaa gccctttgtt tcgtgctgtt cgaatagcct gttttgttga
    15241 cttggaaagt ttatcttctt caaaattttc cttgtatatt ttcgcctgaa tacgaggttg
    15301 aatggtgtct cccatttcct ccgtttttcc tgaccacctt actcccattt gttgcaaact
    15361 atcaataata gccagatttt caggaaattc tgtcttttcc tgattgatta aactttgaga
    15421 taggcaaata cttgggtcaa aagtcacaaa aaccgctctc ttactgcgag cataggactt
    15481 aatagactga atggcaaaat tcaagagttc tttatcccca taatccaata taggtcctct
    15541 tgggatgtaa aacattttat agcctagcgg aagagttcta atcaaaatac tagctgtcgc
    15601 cagtaatttt tcttccctgt aaacaccaaa cttctcatgt tgccaattag acttaacttc
    15661 ctcccaagca ctactttgta atacattggc taattcatgt tctttgacaa actgatcata
    15721 ttctaatgtg ggaatgccaa tttgataacg gtacatttcc tactctcttt cctccagtat
    15781 tttattacta ttctactact ttcgtttgaa aagtctagtg aaaacatatt ttattttagt
    15841 tctactcccc ctatgctgaa gttcaaacta agtcagtctc tcttctaatt tgaaatcaat
    15901 tggtagggtt gttaaaaaaa cttccaattg tttttcccag tagtaccact cgtgagttcc
    15961 agcgctatgg ctataggtca catcaaaacc tagttttttg agatttttca ctgcgagatt
    16021 attggcttcg tacaagaaat cctgttcgcc acaccacgcc caaagtttgg tctttttatc
    16081 cgatttttta gccagacttt caagagaata gggactagtt gtccagtctc taatctctcc
    16141 aaaaacacct ctccagtagg ctggacttcc cagattttga ctttcaggag aaaagttttg
    16201 aaagctgagg gcacctgaaa aactagctgc atgagaaaaa cgatttgtcg caagagccag
    16261 tttgaagcag ccgtaacctc ccatagaaag accagcgata aaggtctttt cacgcttgct
    16321 agtcatatta gggaagaagc gtttcagaac ctgtggcaat tcctctgcta gagccgtgta
    16381 gtagtcaaaa ccatactggg tatcggtgta ccaaccattg ctggtattgg gcataacaac
    16441 gatgagatta gttcctcgaa gcaagcgttc tacattggtc cgcttaagcc aactattatg
    16501 atttccagac atcccgtgca aaaggtacaa gacgggaata tcttcacact ctggttcttc
    16561 cactcgattg gcatcagggt agaggacatt caccccccac tccatatcca atacttgtga
    16621 gtaatactcg attttcatta ctgccatgat tttctccttc tatttttcta taagaaaaag
    16681 ccgaaactcg actttctctc tgtttatttc aacgattatt ttgcttccat gactactggt
    16741 aaaatagctg gacgacgctt ggtttggtca aagagatact tggtcaaatt atctcgaacc
    16801 ttccctttaa gatctgccca gtcaaagtca tctccttgaa gataatcttc taccgtttgg
    16861 ttaatcaatt ctgaactttc acggagaata tcgcgactct tcttgagata aacaaatccg
    16921 cgcgtatgaa cacgagccct agccacaatt ttcttctcac gacggttgac tgtaatagcc
    16981 acgatgaaaa ttccatcctc tgacaagatc ttacggtcac gaagaacaac atttccaaca
    17041 tcaccaatgg cattcccatc aatcaagata tctcctgctg aaaccgatcc agctggaaca
    17101 aagtctccat tctcgtaagc catggtcgtc ccctttttag gaatgaagat gtgttctggc
    17161 aacatcccaa ctgccatggc agccttagcg tgagcatcca actcacgata ctccccttgg
    17221 acagggaaga ggtacttagg ttgcaaaaga ttgatcatca gctgcaaatc acgcacattt
    17281 ccgtgccctg atacatgtaa actttgggta atcaatttga caaccccacc tgcctgataa
    17341 atcatatttt ccacacgcgc aacaaaggct tctttagcaa tagacggagc cgtagcaata
    17401 tagaccaggt ccccatcctt gatttctaca taacgatggc gaccaatcga catcttacga
    17461 agtccattga taggttcacc catacgacct gtctcaagaa taatcaactc atggtcttca
    17521 aagcgagaca tatctttagg cttaatcaag agaatttcgt tggctaaaga caacttctta
    17581 agacgaatcg ctgtgcggac gatattttca atatcaaatc ctgtcaagac gatacgtcga
    17641 cctgttttat ccgcagcgtc aaaaatctgc tgaatacgag aaagattact ggaaacagct
    17701 gcaacgatga tacgaccttc ccagtcagca atagtttggg taatttcatc cctaacttca
    17761 ctttcactag ccacctgaat attgctgtct gcattggccg aatcactgag gagagccagg
    17821 acgccgtcac gaccaatctc tgccaaacga gcaaaatcag ttgcataaga ttcactagcc
    17881 gtttggtcaa atttgaagtc acctgtataa acgatgcttc cttccgatgt cttcaagaca
    17941 attcccagac tctctggaac ggagtaagtc gtagggaaga aggaaaccac tgtcccacca
    18001 aaatcaatct ccgtattctc atcaatgaca tggaaatcat taaatttctt aacggcatca
    18061 tttcctttga caaagagctt tgccaactca atggtcaact cagacccaaa tacaggaact
    18121 ttagcctctg ccaagagata aggtagagca ccaatggcat ccgcatgccc gtgggtcaag
    18181 aaaaccccag caatacggtc gctattttca aaaaggtaat ccatgtttgg aatcaccaca
    18241 tcgaccccta attgttcatt ttcaggatat tttaacccta cattcaaaac aaaaatggac
    18301 tctccaattt cagcaatgta catatttttt ccattctcac gcacaccacc aagtgttgtt
    18361 aaactgatat tactcatttt tcctccaaaa tcttagttta tcttgattat agggcaattc
    18421 taccctctta ttctaaaagt tctgatactt tcagccgaat cttttcctac cattatacca
    18481 tttttttgat gattttcaaa atgaaggtct gttttcaaaa aagagttgat ttcccaactc
    18541 tttcctaact tctactcttt ttccatcaaa aaatcataaa tttcttgcac cgtacccagc
    18601 gccatcattt cttggtcttt aacggtttgt ttgagatttt ggtaaatttg actttctcct
    18661 atctcccgct ttggcgcctc tttattgact gtcatcacac catcttttat cgtcacaaag
    18721 cctagttctt caaatacttg aatcatcttg accagcaaga tttgttgaat attaagatat
    18781 gcagccaaat ctttcagctt gtagcgaata tcaaactctg ggaactggta aatagtcttg
    18841 tacaatttag caaactgatc tctagtccca taacctgtca gataataggt cttgtcaata
    18901 tcatttttga aatagacagc agagaaatgc tgttcctgaa aaatggtctt cagctgagta
    18961 atatcctctg gaatgttttt tacgacaaca gcttcactag ccgcaagatt tggcagttct
    19021 ccaggaaaat ccaagactgg aacaccttct ggcaagactg cattttttcc acgaatgtta
    19081 aaaagttgaa caccttccac tcgcgcatcc accatcatca actggagggc agtttggcca
    19141 ttccattggt tgacagacaa tttaaccgct aactctagat tcttggtttg agaaaactct
    19201 gtcgcccatc tgccttgacc aaaggctacc acttcaaaac tcgcctcacc cttggaaatt
    19261 ttcagcttta gatgggcatt acctgccccc atagtacgag cactttcgac ctgaaaattc
    19321 ttgatataaa aaataggttt ctgattatcc attccaaaag gagctaaacg ttcaaaactt
    19381 ttgaccgttt ccaagctaag tgcctccaaa tccaactctt catctaggtt taacttattc
    19441 ttgccaccag catctgcacc tttttcacga acataatctt ccaaaacctg agataaatct
    19501 gagagttgct caacttccag cgtcataccc gctgcacctg catgacctcc aaaggcgatg
    19561 aagaggtctc gatggggatc cagagcttca aaaatatcga ccgcttccac actacgagca
    19621 ctgcccttgg cacgaccgtc ttctatatta agaacaatga ctgtctgtcc caattcttcc
    19681 aataaacgac cagccacgat tcctagaacc ccaggattcc agccttcctt ggccaagacc
    19741 tgaaccttct tctcaggatc caccatggtc ttggcttctt catagataga ctgaacgatt
    19801 tccttgcgct cttcgttttt ctggtgaatc ataagggcaa tctcatgcgc ttcctcatca
    19861 tcaaatccag tcaacaaatc aatggcagga ttgggatcat ccaagcggcc caaggcattc
    19921 aaacgaggag caatctggaa accaaccgtt tcttctgtta cttcgttggc agcaatccca
    19981 gccatgtcca gcatttcttg cagaccaatg cgctgggtat gacccaacat ttccagacca
    20041 tattgaacta agatacgatt ttcatccgtc agactcacca tatctgcaat agttccaata
    20101 gcgaccaaat caagcaattc cacttgcact tcttctaaca gggcacaagc caacttgaaa
    20161 gcaactccac aaccagccaa atatttaaaa ggataatccg catctggatg ttcaggatgg
    20221 acaatagcat aagcatctgg cagggtttca ggcatggaat gatggtctgt cacaatgaca
    20281 tctactccca tagactgagc caatgcaata gcctcatgac cagcaacccc attgtccacc
    20341 gtcacaatca aggaaattcc ttcttgctcg ataaagtatt tataaacact agcattaggg
    20401 ccatagccat cggtaaaacg atttggcagg taaactcggc actcagcacc aagttgttcc
    20461 aaactttcct tcacaataga agccgaagtc atgccatccg catcatagtc tccataaacg
    20521 agaatatttt ccccttcttc aatagcctga cgaatccgct ccactgcctt gtccatatca
    20581 tggagcagat aagcatcatg taagtcctcc aaggaaggtt ctaaaaactt cttcagactt
    20641 tcttggtcct gaatccctct ctcaaacaat aaccgagcca cctcaggacc cagtccagcc
    20701 ttcttggcta tctttgtaaa atccgcatct tctacctgca gggcaaactg ccattcataa
    20761 gtaggtgtta tcaaaaagac atccactctt tctaagaatt ctattgcttc attataacat
    20821 gatttagacg ttttctctat ccagattgct tttttataac attttatagt atattgaaac
    20881 tagaatagta cacctctact tctaaaatat tgttagaaat cgatttgact gtcccgatcg
    20941 atttgtcctg ttcttatttc actatagtga attttttcag atatggtttg acaagaacat
    21001 tctttcattg tagaatcgtg ttataaaata taacacaaag gagatctctc atggctttag
    21061 tagaatttaa aaacgtcgaa aaatattacg gagactacca cgcactccgc aacatcaatc
    21121 tccgttttga aaaaggacaa gttgttgtcc tgcttggacc ttctggctct gggaagtcca
    21181 ctcttatccg tacgatcaat ggtttagagg ctgttgacaa aggaagtctc ctagtcaatg
    21241 ggcaccaagt tgctggtgcc agccagaaag atttggtacc tcttcgcaag gaagtcggca
    21301 tggtttttca acattttaac ctttatccac acaaaacggt gttagaaaac gtgacacttg
    21361 cgcccattaa agttctagga attgataaaa aagaagctga aaaaaccgcc caaaaatatc
    21421 tggaatttgt aaatatgtga gacaagaaag attcctatcc cgccatgcta tctggtggac
    21481 aaaaacagcg gatcgccatc gctcgtggtc ttgctatgca tccggaactc ctcctctttg
    21541 atgaaccaac atctgctctt gatcctgaga ctatcggaga tgttctagca gttatgcaga
    21601 aactggcgca tgatgggatg aacatgatca tcgttaccca cgaaatgggc tttgctcgag
    21661 aggttgcgga ccgcattatc tttatggccg acggagaagt tttagtagat acgacagatg
    21721 tcgataactt ttttgacaat ccaagcgaac ctcgtgccca acaattcctc agcaaaatta
    21781 tcaaccacga aagtgacaaa gtcaaataag gaggcgccta tgaaaaaaaa ttctttttat
    21841 cagcattatt gattagcctt ttcggccttg ctgctgccaa accagtccag gctgatacta
    21901 gtatcgcaga cattcaaaaa agaggcgaac tggttgtcgg tgtcaaacaa gacgttccca
    21961 attttggtta caaagatccc aagaccggta cttattctgg tatcgaaacc gacttggcca
    22021 agatggtagc tgatgaactc aaggtcaaga ttcgctatgt gccggttaca gcacaaaccc
    22081 gcggccccct tctagacaat gaacaggtcg atatggatat cgcgaccttt accatcacgg
    22141 acgaacgcaa aaaactctac aactttacca gtccctacta cacagacgct tctggatttt
    22201 tggtcaataa atctgccaaa atcaaaaaga ttgaggacct aaacggcaaa accatcggag
    22261 tcgcccaagg ttctatcacc caacgcctaa ttactgaact gggtaaaaag aaaggtctga
    22321 agtttaaatt cgtcgaactt ggttcctacc cagaattgat tacttccctt cacgctcatc
    22381 gtatcgatgc cttttccgtt gaccgctcta ttctgtctgg ctacactagt aaacgcacag
    22441 aactactaga tgatagtttc aagccatctg actacggtat tgttaccaag aaatcaaata
    22501 cagagctcaa cgactatctt gataacttgg ttactaaatg gagcaaggat ggtagtttgc
    22561 agaaacttta tgaccgttac aagctcaaac catctagcca tactgcagat taaggaggac
    22621 accccatgat agatttatca tcttggacag cctattttca ggattttgga caatttttca
    22681 atggtttcct ctttactctt gccctagcga ttggatcctt tatcctcgcc atggtcttag
    22741 gaatcttctt tggtgccatg tcaaccagta aacgtccaat tttacgcatt ttagctcaca
    22801 tctttgtgga attttaccaa aacactcccc tcttggtgca gtttgttatt gttttttatg
    22861 gcctacctct tatcagtgac catactatca tgattccaat ttattggaca gctgttctct
    22921 gcatgggact ctatcacggc gcttatatcg ctgaggttat tcgttcaggg attcagtcta
    22981 ttcctagtgg tcagatggag gccgccttgt cgcaaggttt tacctatatc agtgccatgc
    23041 gcttgattat cttgcctcag accttccgca tcattctccc tccattgacc aaccaaattg
    23101 ttaacctcat caagaacacc tctactgtag ctatcatctc tggagtagac ttgatgtttg
    23161 tgactaagtc ttggtcggct ctcaacggaa actatatccc agccttttta ggtgctgctc
    23221 ttctctactt tgctctatgc ttccctgttg cccagtttgg tcgcaagatg gagcaagcca
    23281 acaaaaaagc ctattcactt taggaggtta ctatggaatc tattttagaa gttttaaccc
    23341 cagataacct agtctttatc tttaaaggat ttggcttgac cctctatatt tctctgattg
    23401 ccatcatcct ctctactatc atcggtacgg tgctagctgt catgagaaat ggcaaaaatc
    23461 ctgtcttacg cattatttcc agtatttata tcgagtttgt gcgcaacgtt cccaaccttc
    23521 tctggatttt tactatcttt ttggtgttca aaatgaaatc cacaccagca ggtattacag
    23581 cctttactct ctttacatca gcagccttgg ctgagattat tcgaggcggt ctcaataccg
    23641 tagacaaggg acagtacgaa gcaggaatgt cacaaggctt cacctcagcc caaatcctct
    23701 actacatcat tctcccacaa gccatccgca aaatgctacc agccatcatt tctcagtttg
    23761 ttaccgtgat taaggatacc agtctcctct actctgttat cgccctacaa gaactctttg
    23821 gagccagcca aattctcatg ggccgttatt tcgaaccaga gcaggtcttc agtctttgca
    23881 tcctgattgc cctcatctac ttcagcttta acctagcaat ttctagcctg tctcatatgc
    23941 tagccaaacg ttggcaacaa gctgcagaat aatactcttc gaaaatctct tcaaaccacg
    24001 tcagcttcac cttgccgtat atatgttact gacttcgtca gttctatcca caacctcaaa
    24061 acggtgtttt gagcagcctg cggctagctt cctagtttgc tctttgattt tcattaagta
    24121 taaacagcca ctctccagtt caattggaga gttttttgat gagagtagat atttatagac
    24181 ctcaatttga caccatacat tttctatgat aaaatgtaac aaattcattt acaacaaatc
    24241 gaaatctaaa tgaaatggaa ttttctatga aatcagtcaa aggactactc tttatcatag
    24301 ctagttttat cttgactctt ttgacttgga tgaacacttc tccccaattc atgattccag
    24361 gactagcttt aacaagccta tctctgactt ttatcctagc cactcgtctc ccactactag
    24421 aaagctggtt tcacggtttg gagaaggtct acaccgtcca caaattcaca gcctttctct
    24481 ccatcatcct actaatcttt cataacttta gtatgggcgg tttgtggggc tctcgcttag
    24541 ctgctcagtt tggtaatctt gccatctata tctttgccag catcatcctt gtcgcctatt
    24601 taggcaaata catccaatac gaagcttggc gatggattca ccgcctggtt tacctagcct
    24661 atattttagg actctttcac atctacatga taatgggcaa tcgtctcctt acatttaatc
    24721 ttctaagttt tcttgttggt agctatgccc ttttaggctt actagctggt ttttatatca
    24781 tttttctata tcaaaagatt tccttcccct atctaggaaa aattacccat ctcaaacgct
    24841 taaatcacga tactagagaa attcaaatcc atcttagcag acctttcaac tatcaatcag
    24901 gacaatttgc ctttctaaag attttccaag aaggctttga aagtgctccg catccctttt
    24961 ctatctcagg aggtcatggt caaactcttt actttactgt taaaaattca ggcgaccata
    25021 ccaataatat ctatgataat cttcaagccg gcagcaaagt aaccctagac agagcttacg
    25081 gacacatgat catagaagaa ggacgagaaa atcaggtttg gattgctgga ggtattggga
    25141 tcaccccctt catctcttac atccgtgaac atcctatttt agataaacag gttcacttct
    25201 actatagctt ccgtggagat gaaaatgcag tctacctaga tttactccgt aactatgctc
    25261 agaaaaatcc taattttgaa ctccatctaa tcgacagtac gaaagacggc tatcttaatt
    25321 ttgaacaaaa agaagtgccc gaacatgcaa ccgtctatat gtgtggtcct atttctatga
    25381 tgaaggcact tgccaaacag attaagaaac aaaatccaaa aacagagctt atttacgaag
    25441 gattcaagtt caaataagta atcatactct cctgggattt cccaggagag ttttttatag
    25501 ccaaatgaaa taaaaccgga acgatggaat tttggcattc aaatcaattg ataagaatat
    25561 tttatagtgg agtgaaatag gatacgaaca aattgattag gaaaatcaaa tgaatttata
    25621 gaaatctttt agcagttatg ttgtcctatt ctagtttcaa aacgctatag aagcagcatt
    25681 gtgctagtct agattcagtt tactatacta aaacgagtag cttgaaatca aaaaacccac
    25741 cctcacaggc aggttttatc tgtattattc agctagatta tgctttacct tctgaaccga
    25801 atacgtcgat acgttcttca accgatgctt ggatagcttt tacaccgtca gccaagaatt
    25861 tacgtgggtc gaagagtttt ttcttgtcgt attctgcttc gtttgcttcg tagtcacgag
    25921 caaatttacg agttgcgtta gcgaatgcga tttggcattc tgtgttaacg ttaactttgg
    25981 caacaccaag tttgatagct gcttggattt gctcatcagg aatacctgat ccaccgtgca
    26041 atacgattgg gaatcctgga agagcttctg tcaatttttg caagtggtca aggtcaagac
    26101 cttcccagtt tactgggtaa gggccgtgga tgttaccgat accagctgcc aagaagtcga
    26161 taccagtttc aaccattgct ttagcgtctt cgattggagc caattcacct ttaccgatga
    26221 ttccgtcttc ttcaccaccg atagtaccaa cttcagcttc tactgagata cctttagcgt
    26281 gtgctttttc aacaacttct ttagccaatt taaggttttc ttcaactgga aggtgtgaac
    26341 cgtcaaacat gattgaagta taaccaactt cgatacactc aagtgcatct tcgtagtgac
    26401 cgtggtcaag gtggatagct actggtacag tgatacccat tgattcaaca aggttagcga
    26461 tcaagttgcg agcaactttg taaccaccca tgtatttagc agcacccatt gaagtttgga
    26521 tcaaaactgg agctttttta gcttctgctg cgcgcaagat agcttgagtc cactcaaggt
    26581 tgtttgtgtt aaatccacca actgcataac cgttgtcacg ggctgcttgg acaaattttt
    26641 ctgctgaaac gattgccatt ttatcaggcc tcctgtatat ttttatgggt catcccattt
    26701 acattgttca ttttatcact ttttgccaaa aaaatctagt ttttcccgca gtttcgattg
    26761 attttcttct aactccatct atgtaaaccc tttctctccc tagtcttgga cgacttttgg
    26821 aaaatctata aagaaggtta aacgattctc ctccatctcg aaacgataag ctaatttttc
    26881 atgttctaat agactcttaa ccacaaagag ccccatacca gaccccttga ccttgcgact
    26941 ggcattgtca gaaaaagact gggctagttt ttcttgttcc tctgagctac agctattttc
    27001 gataaaaagt tctccttctc tttctccaat tcgaactaag ccacctggaa cagagtgctt
    27061 aatggcattg ctgatgagat tagaaagaat caacttcata actgatgggt ttagataagc
    27121 ctgctgatgg gtcaaactat tgtctatctg gagctctctt tccttggcta gcaaggcata
    27181 atctttgacc agattttgcg tcatctggag gaggtcaatt gtttccctat catctcgcaa
    27241 ttcctgcaca gaagagaggg aaagtatctg cagaacatgg tgattgagtt catccacaat
    27301 ccccaaggca actcccagat actggtctct atccttataa cgaccgatat tctctctcat
    27361 attttcgatt aggattttca aactagccag cggtgttttc aattcatgag aagctcctcg
    27421 taggaattcg accttcatct tctccagctg gagaatggct tcattctttt catgcaagtc
    27481 cgcaataaca gtcaagagat gctggtagag gctattgatt tgttccttga gattacctat
    27541 ctcatcctta gaatccacgc gcaatcgcac ttgggaatcc aggtccatca tccgacgggt
    27601 cacccgcttg atttccaaga tcggtgcaac aatagtccga gcgtagatgt aggccaccaa
    27661 gagggaaatc agaaaggagg ccagcaaggt atagggaaga aactggagac tgatttgctc
    27721 cgcttccttt tgtaaatcca tggaagctag aaactggaga atcatagtag caccgtcttg
    27781 cgttttcacc tcgcgctcct caataaagag agaggttgtc tggcggtctg tgtccagagg
    27841 aagactgtcc ttgacttcta acttgtcctc ggtcatctca cctttgacgg tccccttgat
    27901 atcactagtc tgggaataca agtctaacac ttgctcgata ctctgcctat ctttcccttc
    27961 tagggactgg gcaatggctg ttgccttttg accaatggtt tcctgacgat gactcagata
    28021 agtcgaagga aaaagaaaat aaatagctaa atgaaggcag ataaccagaa cactaaatat
    28081 cgagaaggta tagataaata tctttgcaaa taaacctgtt cgtttcattt tcgctccaat
    28141 ttataaccaa cattgcgcac agtgaggata caatccaagt ctagcttttt ccgcaattcc
    28201 ttgatataaa catcaataac acggtcaaag ggaacctcat ctgtcgcttt ccagacggca
    28261 tcgataatct gagatcgagt caaggcccgg ccttcatttt tcactagata gtccagaatt
    28321 tccaactctt tggcattgat aggcacttct tgacctgcga tgcttgcact gtagctttca
    28381 aagtccacct tggtatcctt gtaagaaaag attcgtcctg tatcgtagta gcgcttgaaa
    28441 atcgcgtcca ccctcacttt taaaagggag agggagaaag gtttttccag atagccatct
    28501 gccaaagagg caaaggcact catcttgtat tcctcatctt gaaaagctgt caacatcaag
    28561 acaggaacct gactggtttt acgaatctca gctaggactt ctaagccgtt gagcttgggc
    28621 atctggatat ccagtaaaac cagggccacc tcatagctag aaaattgctc cagagcttcc
    28681 tgaccgtccg ctgcctcaat agtttcatag ccacaatccg tcaaataatc actgaccccc
    28741 tcacggatca tctcttcatc ttctacaatt aaaattttca tactttaact gctctctatt
    28801 ttttattttt cttagaataa atacctactc tattttctat tatagtctct tgctggcctt
    28861 ttgtctgcaa gcaactgacc actagataaa acgttgtgaa attcctttct cataaattcc
    28921 ataactttag tatattatat ttaagcacta aagtacaaag aaagcaactg aaagcaatga
    28981 ttttcaccac tgctttcgga tttattttga attgttaaat agccattcct atccactatt
    29041 cttgaataga aacacaagat gcaatcttta ttctagactc attttttcaa atttattcac
    29101 catccagcaa gagctctttt ggttgttttc taaggagatt gcttgaagca agcgccataa
    29161 cgagaaccac tagaaccaag gcaaggacaa aaatgatgat aaagtctgat gtctgaatgg
    29221 aaatgtctag gctcgacaag gtcttgctaa agccatctac ttctgcacca ccaccaaggt
    29281 tagaggcttg agccgcctta ctagcctgtt tggcaacacc tgaagtcaca ttggcaagga
    29341 cagtgtttcc aattgcacgg gcagtgtaat tagctaggaa gtaagcagaa actagagcag
    29401 ggatagcaat caagatagat tcggtgatga attgacccaa gatacttgcc tgcttgaggc
    29461 cgatagagag gagaattccc acttccttgc gacgggcgtt gatccaaagg ctgagcaaga
    29521 gggcaaggag gagaactgag aagctcaagc taccccagaa gaggaggttg gccatcttgt
    29581 acataccaga gatagattgc tcaagagctg ggtagttaga ggagctcttg acgagtgtgt
    29641 agctcttcca gttgatacca ctgatgccat tcaactcttt cataacatca tccaagttct
    29701 tgtctgctgt tacaaagaag gttgcgtccc cataaatggc tgtgtcttct gtgtatccat
    29761 aaagttttgc agcagtgtga atgtctgtaa tagctgtgtt ttcgtaaagt tcttgtgagt
    29821 aggttactgc tgacttatta tgaccatcaa agagtccctt gattgtcact tcaactgttt
    29881 ccttggctcc tttttcatta tctgcatcgt agatattaga gtccagttta accttgtccc
    29941 ctactttcca gccgtgtttg gctgccaagt ccttgtgcaa gaggatttta tccttgtcgt
    30001 cgttggttaa gtgctctcct tcgactagtt tataagaacc agagacaaac ttgtcttctt
    30061 tagaggagtc attgacacct gtaatcatca agctacttcc aaaacgcttg gcacgatcag
    30121 cagtgagatt cttcttggtt tctggcgttt caatcaggtc atatccagtc aaatctccga
    30181 tagcgttgat acgtttgaca taagactcga tggccttgtt ttcggtgatt tttttgatgt
    30241 cttcaccctt gatattccca gcaccacgag gcgttccttg gttgacgcga cgattgattt
    30301 gcatggagaa gctattagtg atatttttaa aggtctcctg agaagccttg gcagtagctc
    30361 ccttgattga caagccgacc aaactcaagc tcgccatgag gagaataatc aggaagatga
    30421 caatcgattt gaaaaacttc cttgtaacat aggcaaatgc gttgtgtaac atagattccc
    30481 tttctagatt ttgttttaat cattctatca aaataagctc aaattattta ctagtattgc
    30541 gcgtttcagt cagtttctta tcctttaatt caagtgtaat atctgacgct tgtgccactt
    30601 ctttactgtg agttacgaca atcacacatt tacctgtttt ctgggcaagt gatttgagta
    30661 gttcgacaat atctccagca gttttaggat ccagatttcc tgttggctca tcagctagaa
    30721 taactggagc ttctgagacc aaactgcgag caatggcaac acgttgctgt tgaccacctg
    30781 ataactggag aacattccgc ttgatctggc tttcatccaa accaagctca agaagtgtat
    30841 ccttgcttgc ctttttgttg accaagcgga tattttccag cggagaaaga taatctatca
    30901 agttataatt ttgaaagacc agggaaatat ggtgcatgcg atggtaagaa tagcccttct
    30961 tacgaatatc ctctccttga aaaaggatag aaccttcaac aggactatct agaccagcaa
    31021 gtagggacaa gagtgtggat tttcctgctc ctgactcccc aataatactg taaaattttc
    31081 caggttcaaa attataatcg atctgatata ggactgcttc agcagtattc ttataacggt
    31141 aggtaacatc ttgtaattgt aataaagtca tgatttctcc ttcttaacta atagatgata
    31201 aaatttcttt cggtgatttt ctaaataaga ataggaaaca aagggctaca gataagcaac
    31261 taagcagaac tagaaaaaca taggattctg caaaagataa gatgctagtt gataaactgc
    31321 ttgctttggc tagtgtatct tgtaagcttg cctgatctcc acttgctagt agagtttgga
    31381 gtagataact tgtgattccg tttcctgcaa caaatgctgg aagcaaagct ccaagagata
    31441 ccaaaactac ctctaaacag aattgtagga agatcgagct cttgcctttt ccaagtgcaa
    31501 gtaaaatccc cacttcatag acccgttctc tcaaccagag agacaaaacc agaattaagg
    31561 ctccagctcc tgctatcaac atcccataaa ggaagatggt caagaaggtt tggaaagttg
    31621 caactgagtc tttgatttgt tcaaaagcct tgttttcctt ttcgacttgg tagccttgat
    31681 tttccaaggc caagttttct acctgcttca tgagtccgtc catttcctta ggattttcta
    31741 catagaagcg tgctgcactg acttgagctt cactattgcc caaaagggtt tggctacttt
    31801 catagtctgt aaagacttga ttttcactga agtcagaaga caagcctgtg aatttctctt
    31861 gttttttacc agaaaagatg ccgataatct caaactctac tgtttgtcct tttccagatt
    31921 cagactgacc agcatccaag ccaatcttgt catgaagtga aagaccgttc ttcttagcca
    31981 attcttcgtg gataaggatt ttcttggaat cccctttttg aaggtgtcgc ccttctttta
    32041 gattgaaagc cgaactggta aaggttacat ccttggatga atcctcaaga gccgttaagc
    32101 taaccaagtt attgtctgca gctgataaat catcacgctc cacgctctgc tcaccagtca
    32161 ctgcttcctt gtcttttagt tttgcgaccg tctcaagttc aggagagaca ttttccagcc
    32221 ccttaatctt gcttacagat gctaggtctg acaacttgaa tgtctgacca ttctctatct
    32281 tcttaataga aaaagatgta ttgagtgatt tataaagatt gctttctact gttttgttgg
    32341 acttcatcag agtcaaacag gctgaaattc cggccaataa gaccaataaa atcagaaata
    32401 aaataaaact tctcagtcgc tttctgctga cataagccca agatctttgg attggattca
    32461 tttgtcacct ccatatttgt aagactatta taaaacccaa atatgaaatg tttatgaaat
    32521 acgaaaaaaa a
//
LOCUS       DAVBBO010000020        31170 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ST1
            SAMEA2066453-rid20184263.denovo.020, whole genome shotgun sequence.
ACCESSION   DAVBBO010000020 DAVBBO010000000
VERSION     DAVBBO010000020.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2066453
            Sequence Read Archive: ERR351777
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 31170)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 31170)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980402.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980402.1
            Genome Coverage       :: 176x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:17:33
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,141
            CDSs (total)                      :: 2,104
            Genes (coding)                    :: 1,953
            CDSs (with protein)               :: 1,953
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 16S)
            partial rRNAs                     :: 1 (23S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 151
            CDSs (without protein)            :: 151
            Pseudo Genes (ambiguous residues) :: 0 of 151
            Pseudo Genes (frameshifted)       :: 73 of 151
            Pseudo Genes (incomplete)         :: 76 of 151
            Pseudo Genes (internal stop)      :: 40 of 151
            Pseudo Genes (multiple problems)  :: 32 of 151
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..31170
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2066453-rid20184263.denovo.020"
                     /strain="ST1"
                     /db_xref="taxon:1313"
     gene            complement(1..389)
                     /locus_tag="VQU30_000918"
                     /pseudo
     CDS             complement(1..389)
                     /locus_tag="VQU30_000918"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="frameshifted; incomplete; missing C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase family protein"
     gene            384..638
                     /locus_tag="VQU30_000919"
     CDS             384..638
                     /locus_tag="VQU30_000919"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001244258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit delta"
                     /protein_id="HET2447050.1"
                     /translation="MHRTTIPYFVSQEVYWKVRNIGAEAIRRNCERGAIFSGKIKHHE
                     DSQFKGDHYVECYAVLDNTVIARDRITVPIDPLCGKDFIE"
     gene            982..2316
                     /gene="trmFO"
                     /locus_tag="VQU30_000920"
     CDS             982..2316
                     /gene="trmFO"
                     /locus_tag="VQU30_000920"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000083696.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methylenetetrahydrofolate--tRNA-(uracil(54)-
                     C(5))-methyltransferase (FADH(2)-oxidizing) TrmFO"
                     /protein_id="HET2447051.1"
                     /translation="MSQSYINVIGAGLAGSEAAYQIAERGIPVKLYEMRGVKSTPQHK
                     TDNFAELVCSNSLRGDALTNAVGLLKEEMRRLGSVILESAEATRVPAGGALAVDRDGF
                     SQMVTEKVANHPLIEVVRDEITELPTDVITVIATGPLTSDALAEKIHALNDGDGFYFY
                     DAAAPIIDVNTIDMSKVYLKSRYDKGEAAYLNAPMTKQEFMDFHEALVNAEEAPLNSF
                     EKEKYFEGCMPIEVMAKRGIKTMLYGPMKPVGLEYPDDYTGPRDGEFKTPYAVVQLRQ
                     DNAAGSLYNIVGFQTHLKWGEQKRIFQMIPGLENAEFVRYGVMHRNSYMDSPNLLEQT
                     YRSKKQPNLFFAGQMTGVEGYVESAASGLVAGINAARLFKEESEAIFPETTAIGSLAH
                     YITHADSKHFQPMNVNFGIIKELEGERIRDKKARYEKIAERALADLEEFLTV"
     gene            2400..3137
                     /locus_tag="VQU30_000921"
     CDS             2400..3137
                     /locus_tag="VQU30_000921"
                     /EC_number="2.7.4.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000013002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UMP kinase"
                     /protein_id="HET2447052.1"
                     /translation="MANPKYKRILIKLSGEALAGERGVGIDIQTVQTIAKEIQEVHSL
                     GIEIALVIGGGNLWRGEPAAEAGMDRVQADYTGMLGTVMNALVMADSLQQVGVDTRVQ
                     TAIAMQQVAEPYVRGRALRHLEKGRIVIFGAGIGSPYFSTDTTAALRAAEIEADAILM
                     AKNGVDGVYNADPKKDKTAVKFEELTHRDVINKGLRIMDSTASTLSMDNDIDLVVFNM
                     NQSGNIKRVVFGENIGTTVSNNIEEKE"
     gene            3146..3703
                     /gene="frr"
                     /locus_tag="VQU30_000922"
     CDS             3146..3703
                     /gene="frr"
                     /locus_tag="VQU30_000922"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006148672.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome recycling factor"
                     /protein_id="HET2447053.1"
                     /translation="MANAIIEKAKERMTQSHQSLAREFGGIRAGRANASLLDRIHVEY
                     YGVETPLNQIASITIPEARVLLVTPFDKSSLKDIERALNASDLGITPANDGSVIRLVV
                     PALTEETRRDLAKEVKKVGENAKVAVRNIRRDAMDEAKKQEKAKEITEDELKTLEKDI
                     QKVTDDAVKHIDDMTANKEKELLEV"
     gene            3763..4617
                     /gene="cvfB"
                     /locus_tag="VQU30_000923"
     CDS             3763..4617
                     /gene="cvfB"
                     /locus_tag="VQU30_000923"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001095444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding virulence regulatory protein CvfB"
                     /protein_id="HET2447054.1"
                     /translation="MNTNLASFIVGLIIDENDRFYFVQKDGQTYALAKEEGQHTVGDT
                     VKGFAYTDMKQKLRLTSLEVTATQDQFGWGRVTEVRKDLGVFVDTGLPDKEIVVSLDI
                     LPELKELWPKKGDQLYIRLEVDKKDRIWGLLAYQEDFQRLARPAYNNMQNQNWPAIVY
                     RLKLSGTFVYLPENNMLGFIHPSERYAEPRLGQVLDARVIGFREVDRTLNLSLKPRSF
                     EMLENDAQMILTYLESNGGFMTLNDKSSPDDIKATFGISKGQFKKALGGLMKAGKIKQ
                     DQFGTELI"
     gene            4626..4841
                     /locus_tag="VQU30_000924"
     CDS             4626..4841
                     /locus_tag="VQU30_000924"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002894860.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YozE family protein"
                     /protein_id="HET2447055.1"
                     /translation="MRKSFYTWLMTERNPKSNNPKAILADLAFEEAAFPKHTDDFDEV
                     SRFLEEHASFSFNLGDFDSIWQEYLEH"
     gene            4927..5895
                     /locus_tag="VQU30_000925"
     CDS             4927..5895
                     /locus_tag="VQU30_000925"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001860490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PhoH family protein"
                     /protein_id="HET2447056.1"
                     /translation="MKEHSIDIQLSHPDDLFHLFGSNERHLRLMEEELDVVIHARTEI
                     VQVLGEESACEEARQVIQALMALVNRGMTVGTPDVVTAISMVKNDEIDKFVALYEEEI
                     IKDNTGKPIRVKTLGQKLYVDSVKQHDVTFGIGPAGTGKTFLAVTLAVTALKRGQVKR
                     IILTRPAVEAGESLGFLPGDLKEKVDPYLRPVYDALYQILGKDQTTRLMEREIIEIAP
                     LAYMRGRTLDDAFVILDEAQNTTIMQMKMFLTRLGFHSKMIVNGDISQIDLPRNVKSG
                     LIDAQEKLKNIHQIDFVHFSAKDVVRHPVVAQIIRAYEYSTEVAHD"
     gene            6075..6575
                     /locus_tag="VQU30_000926"
     CDS             6075..6575
                     /locus_tag="VQU30_000926"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000566985.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HET2447057.1"
                     /translation="MIDQLSKYYSCRILTEKDIPSILSLYESNPLYFQHCPPEPNFAT
                     VKEDMLCLPEGKAKADKFFVGFWNGSDLVAVMDFVYAYPDEETVFIGLFMVDQAYQRK
                     GIGSHIVTEALAYFAKNFRKARLAYVKGNPQSQHFWEKQGFKSIGCEVKQELYTVVIA
                     EQSLED"
     gene            6578..6838
                     /locus_tag="VQU30_000927"
                     /pseudo
     CDS             6578..6838
                     /locus_tag="VQU30_000927"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003069408.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="TfoX/Sxy family protein"
     gene            complement(7205..8316)
                     /gene="ald"
                     /locus_tag="VQU30_000928"
                     /pseudo
     CDS             complement(7205..8316)
                     /gene="ald"
                     /locus_tag="VQU30_000928"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004253293.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="alanine dehydrogenase"
     gene            8493..9062
                     /locus_tag="VQU30_000929"
     CDS             8493..9062
                     /locus_tag="VQU30_000929"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000443767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HET2447058.1"
                     /translation="MESIFVKFAQYPSIETERLLLRPVTLDDAEAMFDYASDKGNTRY
                     TFPTNQSLEETKNNIAQFYLANPLGRWGIELKDNGKFIGTIDLHKIDPVLKKAAIGYI
                     INKKYWNQGLTTEANRAVIELAFEKIGMNKLTALHDKANPASGKVMEKSGMRFSHAEP
                     YACMDQHEKGRIVTRVHYVLTKEDYFANK"
     gene            9130..9780
                     /locus_tag="VQU30_000930"
     CDS             9130..9780
                     /locus_tag="VQU30_000930"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000387331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-hairpin-helix domain-containing protein"
                     /protein_id="HET2447059.1"
                     /translation="MEAIIEKIKEYKIIVICTGLGLLVGGFFLLKPAPQTSVKETNLQ
                     AEVAAVSKDSSTGKEVNKEEKEEPVEQDLITVDVKGAVKSPGIYDLPVGSRVNDAVQK
                     AGGLTEQADSKSLNLAQKVSDEALVYVPTKGEEAVSQQTGSGTASSTSKEKKVNLNKA
                     SLEELKQVKGLGGKRAQDIIDHREANGKFKSVDELKKVSGIGAKTIEKLKDYVTVD"
     gene            9764..12004
                     /locus_tag="VQU30_000931"
     CDS             9764..12004
                     /locus_tag="VQU30_000931"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398664.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA internalization-related competence protein
                     ComEC/Rec2"
                     /protein_id="HET2447060.1"
                     /translation="MLQWIKNFSIPLIYLSFLLLWLYYAIFSVSYFALLGFVFLLVCL
                     FIQFPWKSAGKVLVICGVFGFWFLFQTWQQSQVSQNLVDSVERVRILPDTIKVNGDSL
                     SFRGKSDGRAFQVYYKLQSEEEKEAFQALTDLHEIGLEGKLSEPEGQRNFGGFDYQGY
                     LKTQGIYQTLNIKRIQSLQKVGSWDIGENLSSLRRKAVVWIKMHFPDPMRNYMTGLLL
                     GHLDTDFEEMNELYSSLGIIHLFALSGMQVGFFMDGFKKLLLRLGLTQEKLKWLTYPF
                     SLIYAGLTGFSASVIRSLLQKLLAQHGVKGLDNFALTVLVLFIVMPNFFLTAGGVLSC
                     AYAFILTMTSKEGEGLKAVTSESLVISLGILPILSFYFAEFQPWSILLTFVFSFLFDL
                     VFLPLLSILFVLSFLYPVIQLNFIFEWLEGIIRLVSQVASRPLVFGQPNEWLLILLLI
                     SLALVYDLRKNIKKLTVLCLLITGLFLLTKHPLENEITMLDVGQGESIFLRDVTGKTI
                     LIDVGGKAESYKKIKKWQEKMTTSNAQRSLIPYLKSRGVAKIDQLILTNTDKEHVGDL
                     SEMTKAFHVGEILVSKDSLKQKEFVAELQATQTKVRSMIVGENLPIFGSQLEVLSPRK
                     MGDGGHDDTLVLYGKFLDKQFLFTGNLEEKGEKDLLKHYPDLKVNVLKASQHGNKKSS
                     SPAFLEKLKPELTLISVGKSNRMKLPHQETLTRLEGINSKVYRTDQQGAIRFKGLDSW
                     KIESVR"
     gene            12184..12372
                     /locus_tag="VQU30_000932"
     CDS             12184..12372
                     /locus_tag="VQU30_000932"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001810955.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2447061.1"
                     /translation="MTVTKSYKYDWNTVLEYSTNYHDHQYAWIPEWSRYYSYSEYKVG
                     GGWNYARYEVINYYTGGY"
     gene            12404..12991
                     /locus_tag="VQU30_000933"
     CDS             12404..12991
                     /locus_tag="VQU30_000933"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000939891.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET2447062.1"
                     /translation="MLNLTHVTLKTRQVILQDADFTFKKGRIYGLLAINGSGKTTLFR
                     AMSKLLPLSSGHIAVPPSLFYYESVEWLDGNLSGMDYLRLIKNIWKSDLNLRDEIAYW
                     EMADYISLPIRKYSLGMKQRLVIAMYFLSQAKCWLMDEITNGLDEYYRQKFFDRLAQI
                     DRQEQLVLLSSHYKEELVDICDRVVTIHQGQIEEV"
     gene            12995..14170
                     /locus_tag="VQU30_000934"
     CDS             12995..14170
                     /locus_tag="VQU30_000934"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000655966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2447063.1"
                     /translation="MKDVSLFLLKKVFKSRLNWIILALFVSVLGVTFYLNSQTANSHS
                     LESRLESRIAANERAINENEEKLSQMSDTSSEEYQFAKNNLDVQKNLLTRKTEILTLL
                     KEGRWKEAYYLQWKDEEKNYEFVSNDPTASSGLKMGVDRERKIYQALYPLNIKAHTLE
                     FPTHGIDQIVWILEVIIPSLFVVAIIFMLTQLFAERYQNHLDTAHLYPVSKVTFAISS
                     LGVGVGYVTVLFIGICGFSFLVGSLISGFGQLDYPYPIYSLVNQEVTIGKIQDVLFPG
                     LLLAFLAFIVIVEVVYLIAYFFKQKMPVLFLSLIGIVGLLFGIQTIQPLQRIAHLIPF
                     TYLRSVEILSGRLPKQIDNVDLNWSMGMVLLPCLIIFLLLGILFIERWGSSQKKRIF"
     misc_feature    14344..14475
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00558"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="ribosomal protein L20 leader region; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /db_xref="RFAM:RF00558"
     gene            14491..15021
                     /gene="infC"
                     /locus_tag="VQU30_000935"
     CDS             14491..15021
                     /gene="infC"
                     /locus_tag="VQU30_000935"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000848185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-3"
                     /protein_id="HET2447064.1"
                     /translation="MKTIAKQDLFINDEIRVREVRLIGLEGEQLGIKPLSEAQALADN
                     ANVDLVLIQPQAKPPVAKIMDYGKFKFEYQKKQKEQRKKQSVVTVKEVRLSPTIDKGD
                     FDTKLRNARKFLEKGNKVKVSIRFKGRMITHKEIGAKVLAEFAEATQDIAIIEQRAKM
                     DGRQMFMQLAPATDKK"
     gene            15054..15254
                     /gene="rpmI"
                     /locus_tag="VQU30_000936"
     CDS             15054..15254
                     /gene="rpmI"
                     /locus_tag="VQU30_000936"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001125942.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L35"
                     /protein_id="HET2447065.1"
                     /translation="MPKQKTHRASAKRFKRTGSGGLKRFRAYTSHRFHGKTKKQRRHL
                     RKASMVHSGDYKRIKAMLTRLK"
     gene            15306..15665
                     /gene="rplT"
                     /locus_tag="VQU30_000937"
     CDS             15306..15665
                     /gene="rplT"
                     /locus_tag="VQU30_000937"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019786714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L20"
                     /protein_id="HET2447066.1"
                     /translation="MARVKGGVVSRKRRKRILKLAKGYYGAKHILFRTAKEQVMNSYY
                     YAYRDRRQKKRDFRKLWITRINAAARMNGLSYSQLMHGLKLAEIEVNRKMLADLAVND
                     AVAFTALADAAKAKLGK"
     gene            15723..16103
                     /locus_tag="VQU30_000938"
     CDS             15723..16103
                     /locus_tag="VQU30_000938"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398837.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HET2447067.1"
                     /translation="MASKMLHTCLRVENLEKSIAFYQDAFGFKELRRRDFPDHAFTIV
                     YLGLEGDDYELELTYNYDHGPYVVGDGFAHIALSTPDLEALHQEHSAKGYEVTEPNGL
                     PGTTPNYYFVKDPDGYKVEVIREK"
     gene            16353..17153
                     /locus_tag="VQU30_000939"
     CDS             16353..17153
                     /locus_tag="VQU30_000939"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004254684.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotate dehydrogenase electron transfer
                     subunit"
                     /protein_id="HET2447068.1"
                     /translation="MNPTCKKRLGVIRLETMKVVAQEEIAPAIFELVLEGEMVEAMRA
                     GQFLHLRVPDDAHLLRRPISISSIDKANKQCHLIYRIEGAGTAIFSTLSQGDTLDVMG
                     PQGNGFDLSDLDEQNQVLLVGGGIGVPPLLEVAKELHERGVKVVTVLGFANKDAVILK
                     TELAQYGQVFVTTDDGSYGIKGNVSVVINDLDSQFDAVYSCGAPGMMKYINQTFDDHP
                     RAYLSLESRMACGMGACYACVLKVPESETVNQRVCEDGPVFRTGTVVL"
     gene            17116..18102
                     /locus_tag="VQU30_000940"
     CDS             17116..18102
                     /locus_tag="VQU30_000940"
                     /EC_number="1.3.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013193458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotate dehydrogenase"
                     /protein_id="HET2447069.1"
                     /translation="MVLFSAQEQLYYKEKIMTTNRLQVSLPGLDLKNPIIPASGCFGF
                     GQEYAKYYDLNLLGSIMIKATTLEPRFGNPTPRVAETPAGMLNAIGLQNPGLEVVLAE
                     KLPWLEREYPNLPIIANVAGFSKQEYAAVSHGISKATNVKAIELNISCPNVDHCNHGL
                     LIGQDPDLAYDVVKAAVEASEVPVYVKLTPSVTDIVTVAKAAEDAGASGLTMINTLVG
                     MRFDLKTRKPILANGTGGMSGPAVFPVALKLIRQVAQTTDLPIIGMGGVDSAEAALEM
                     YLAGASAIGVGTANFTNPYACPDIIENLPKVMDKYGISSLEELRQEVKESLR"
     gene            18144..20045
                     /locus_tag="VQU30_000941"
     CDS             18144..20045
                     /locus_tag="VQU30_000941"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010976495.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucosaminidase domain-containing protein"
                     /protein_id="HET2447070.1"
                     /translation="MNLGEFWYNKINKNRGRRLMKKVRFIFLALLFFLASPEGAMASD
                     GTWQGKQYLKEDGSQAANEWVFDTHYQSWFYIKADANYAENEWLKQGDDYFYLKSGGY
                     MAKSEWVEDKGAFYYLDQDGKMKRNAWVGTSYVGATGAKVIEDWVYDSQYDAWFYIKA
                     DGQHAEKEWLQIKGKDYYFKSGGYLLTSQWINQAYVNASGAKVQQGWLFDKQYQSWFY
                     IKENGNYADKEWIFENGHYYYLKSGGYMAANEWIWDKESWFYLKFDGKIAEKEWVYDS
                     HSQAWYYFKSGGYMTANEWIWDKESWFYLKSDGKMAEKEWVYDSHSQAWYYFKSGGYM
                     AKNETVDGYQLGSDGKWLGGKATNENAAYYQVVPVTANVYDSDGEKLSYISQGSVVWL
                     DKDRKSDDKRLAITISGLSGYMKTEDLQALDASKDFIPYYESDGHRFYHYVAQNASIP
                     VASHLSDMEVGKKYYSADGLHFDGFKLENPFLFKDLTEATNYSAEELDKVFSLLNINN
                     SLLENKGATFKEAEEHYHINALYLLAHSALESNWGRSKIAKDKNNFFGITAYDTTPYL
                     SAKTFDDVDKGILGATKWIKENYIDRGRTFLGNKASGMNVEYASDPYWGEKIASVMMK
                     INEKLGGKD"
     gene            complement(20106..21761)
                     /gene="pavA"
                     /locus_tag="VQU30_000942"
     CDS             complement(20106..21761)
                     /gene="pavA"
                     /locus_tag="VQU30_000942"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_094859469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rqc2 family fibronectin-binding protein PavA"
                     /protein_id="HET2447071.1"
                     /translation="MSFDGFFLHHIVEELRSELVNGRIQKINQPFEQELVLQIRSNRQ
                     SHRLLLSAHPVFGRIQLTQTTFENPAQPSTFIMVLRKYLQGALIESIEQVENDRIVEI
                     TVSNKNEIGDHIQATLIIEIMGKHSNILLVDKSSHKILEVIKHVGFSQNSYRTLLPGS
                     TYIAPPSTKSLNPFTIKDEKLFEILQTQELTAKNLQSLFQGLGRDTANELERILVSEK
                     LSAFRNFFNQETKPCLTETSFSPVPFANQVGEPLANLSDLLDTYYKDKAERDRVKQQA
                     SELIRRVENELQKNRHKLKKQEKELLATDNAEEFRQKGELLTTFLHQVPNDQDQVILD
                     NYYTNQPIMIALDKALTPNQNAQRYFKRYQKLKEAVKYLTDLIEETKATILYLESVET
                     VLNQAGLEEIAEIREELIQTGFIRRRQREKIQKRKKLEQYLASDGKTIIYVGRNNLQN
                     EELTFKMARKEELWFHAKDIPGSHVVISGNLDPSDAVKTDAAELAAYFSQGRLSNLVQ
                     VDMIEVKKLNKPTGGKPGFVTYTGQKTLRVTPDSKKIASMKKS"
     gene            21866..22363
                     /gene="ybeY"
                     /locus_tag="VQU30_000943"
     CDS             21866..22363
                     /gene="ybeY"
                     /locus_tag="VQU30_000943"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018380869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA maturation RNase YbeY"
                     /protein_id="HET2447072.1"
                     /translation="MYIEMVDETGQVSKEMLQQTQEILEFAAQKLGKEDKEMAVTFVT
                     NERSHELNLGYRDTDRPTDVISLEYKPELEIAFDEEDLLENPELAEMMSEFDAYIGEL
                     FISIDKAHEQAEEYGHSFEREMGFLAVHGFLHINGYDHYTPEEEAEMFGLQEEILTAY
                     GLTRQ"
     gene            22344..22739
                     /locus_tag="VQU30_000944"
     CDS             22344..22739
                     /locus_tag="VQU30_000944"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000378166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase"
                     /protein_id="HET2447073.1"
                     /translation="MDSQDNKRKWKNRDLISSLEFAITGIFTAIKEERNMRKHAVTAL
                     VVILAGFGFQVSRIEWLFLLLSIFLVVAFEIINSAIENVVDLASHYHFSMLAKNAKDM
                     AAGAVLVVSLFAALTGALIFLPRIWDLLF"
     gene            22756..23655
                     /gene="era"
                     /locus_tag="VQU30_000945"
     CDS             22756..23655
                     /gene="era"
                     /locus_tag="VQU30_000945"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002935752.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase Era"
                     /protein_id="HET2447074.1"
                     /translation="MTFKSGFVAILGRPNVGKSTFLNHVMGQKIAIMSDKAQTTRNKI
                     MGIYTTDKEQIVFIDTPGIHKPKTALGDFMVESAYSTLREVDTVLFMVPADEARGKGD
                     DMIIERLKAAKVPVILVVNKIDKVHPDQLLSQIDDFRNQMDFKEIVPISALQGNNVSR
                     LVDILSENLDEGFQYFPSDQITDHPDRFLVSEMVREKVLHLTREEIPHSVAVVVDSMK
                     RDEETDKVHIRATIMVERDSQKGIIIGKGGAMLKKIGSMARRDIELMLGDKVFLETWV
                     KVKKNWRDKKLDLADFGYNEREY"
     gene            23704..24528
                     /gene="mutM"
                     /locus_tag="VQU30_000946"
     CDS             23704..24528
                     /gene="mutM"
                     /locus_tag="VQU30_000946"
                     /EC_number="3.2.2.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001114577.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-formamidopyrimidine glycosylase"
                     /protein_id="HET2447075.1"
                     /translation="MPELPEVETVCRCLEKLIIGKKISSIEIRYPKMIKTDLEEFQRE
                     LPSQIIESMGRRGKYLLFYLTDKVLISHLRMEGKYFYYPDQGPERKHAHVFFHFEDGG
                     TLVYEDVRKFGTMELLVPDLLDAYFISKKLGPEPSEQDFDLQVFQSALAKSKKPIKSH
                     LLDQTLVAGLGNIYVDEVLWRAQVHPARSSQTLTAEEATAIHDQTIAVLSQAVEKGGS
                     TIRTYTNAFGEDGSMQDFHQVYDKTGQGCVRCGTIIEKIQLGGRGTHFCPNCQRRD"
     gene            24528..25133
                     /locus_tag="VQU30_000947"
     CDS             24528..25133
                     /locus_tag="VQU30_000947"
                     /EC_number="2.7.1.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004259526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dephospho-CoA kinase"
                     /protein_id="HET2447076.1"
                     /translation="MGKIIGITGGIASGKSTVTNFLRQQGFQVVDADAVVHQLQKPGG
                     RLFEALVQHFWQEIILENGELNRPLLASLIFSNPDEREWSKQIQGEIIREELATLREQ
                     LAQTEEIFFMDIPLLFEQDYSDWFAETWLVYVDRDAQVERLMKRDQLSKDEAESRLAA
                     QWPLEKKKDLASQVLDNNGNQNQLLNQVHILLEGGRQDDRD"
     gene            25120..26319
                     /locus_tag="VQU30_000948"
     CDS             25120..26319
                     /locus_tag="VQU30_000948"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000136121.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux MFS transporter"
                     /protein_id="HET2447077.1"
                     /translation="MTEINWKDNLRIAWFGNFLTGASISLVVPFMPIFVENLGVGSEQ
                     VAFYAGLAISVSAISAALFSPIWGILADKYGRKPMMIRAGLAMTITMGGLAFVPNIYW
                     LIFLRLLNGVFAGFVPNATALIASQVPKEKSGSALGTLSTGVVAGTLTGPFIGGFIAE
                     LFGIRTVFLLVGSFLFLAAILTICFIKEDFQPVAKEKAIPTKELFTSVKYPYLLLNLF
                     LTSFVIQFSAQSIGPILALYVRDLGQTENLLFVSGLIVSSMGFSSMMSAGVMGKLGDK
                     VGNHRLLVVAQFYSVIIYLLCANASSPLQLGLYRFLFGLGTGALIPGVNALLSKMTPK
                     AGISRVFAFNQVFFYLGGVVGPMAGSAVAGQFGYHAVFYATSLCVAFSCLFNLIQFRT
                     LLKVKEI"
     gene            26319..26468
                     /gene="rpmG"
                     /locus_tag="VQU30_000949"
     CDS             26319..26468
                     /gene="rpmG"
                     /locus_tag="VQU30_000949"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008809064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L33"
                     /protein_id="HET2447078.1"
                     /translation="MRVKINLKCSSCGSINYLTSKNSKTHPDKIEVLKYCPKERKVTL
                     HLESK"
     gene            26508..26741
                     /gene="secG"
                     /locus_tag="VQU30_000950"
     CDS             26508..26741
                     /gene="secG"
                     /locus_tag="VQU30_000950"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012000186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecG"
                     /protein_id="HET2447079.1"
                     /translation="MYNLLLTILLVLSVVIVIAIFMQPTKNQSSNVFDASSGDLFERS
                     KARGFEAVMQRLTGILVFFWLAIALALTVLSSR"
     gene            26843..29197
                     /gene="rnr"
                     /locus_tag="VQU30_000951"
     CDS             26843..29197
                     /gene="rnr"
                     /locus_tag="VQU30_000951"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000653285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease R"
                     /protein_id="HET2447080.1"
                     /translation="MKDRIKEYLQDKGKVTVNDLAQALGKDSSKDFRELIKTLSLMER
                     KHQIRFEEDGSLTLEIKKKHEITLKGIFHAHKNGFGFVSLEGEEDDLFVGKNDVNYAI
                     DGDTVEVVIKKVADRNKGTAAEAKIIDILEHSLTTVVGQIVLDQEKPKYAGYIRSKNQ
                     KISQPIYVKKPALKLEGTEVLKVFIDKYPSKKHDFFVASVLDVVGHSTDVGIDVLEVL
                     ESMDIVSEFPEAVVKEAESVPDAPSQKDMEGRLDLRDEITFTIDGADAKDLDDAVHIK
                     ALKNGNLELGVHIADVSYYVTEGSALDKEALNRATSVYVTDRVVPMLPERLSNGICSL
                     NPQVDRLTQSAIMEIDKHGRVVNYTITQTVIKTSFRMTYSDVNDILAGDEEKRKEYHK
                     IVSSIELMAKLHETLENMRVKRGALNFDTNEAKILVDKQGKPVDIVLRQRGIAERMIE
                     SFMLMANETVAEHFSKLDLPFIYRIHEEPKAEKVQKFIDYASSFGLRIYGTASEISQE
                     ALQDIMRAVEGEPYADVLSMMLLRSMQQARYSEHNHGHYGLAADYYTHFTSPIRRYPD
                     LLVHRMIRDYGRSKEIAEHFEQVIPEIATQSSNRERRAIEAEREVEAMKKAEYMEEYV
                     GEEYDAVVSSIVKFGLFVELPNTVEGLIHITNLPEFYHFNERDLTLRGEKSGITFRVG
                     QQIRIRVERADKMTGEIDFSFVPSEFDVIEKGLKQSSHSGRGRGSNRRSDKKEDKRKS
                     GRSNDKRKHSQKDKKKKGKKPFYKEVAKKGAKHGKGRGKGRRTK"
     gene            29160..29627
                     /gene="smpB"
                     /locus_tag="VQU30_000952"
     CDS             29160..29627
                     /gene="smpB"
                     /locus_tag="VQU30_000952"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002894882.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SsrA-binding protein SmpB"
                     /protein_id="HET2447081.1"
                     /translation="MAKGEGKVVAQNKKARHDYTIVDTLEAGMVLTGTEIKSVRAARI
                     NLKDGFAQVKNGEVWLSNVHIAPYEEGNIWNQEPERRRKLLLHKKQIQKLEQETKGTG
                     MTLVPLKVYIKDGYAKLLLGLAKGKHDYDKRESIKRREQNRDIARVMKAVNQR"
     gene            29643..30503
                     /gene="tehB"
                     /locus_tag="VQU30_000953"
     CDS             29643..30503
                     /gene="tehB"
                     /locus_tag="VQU30_000953"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000413836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SAM-dependent methyltransferase TehB"
                     /protein_id="HET2447082.1"
                     /translation="MEKLVAYKRMPLWNKQTMPEDVQQKHNTKVGTWGKITVLKGALK
                     FIELTEEGEVLAEHLFEAGADNPMAQPQAWHRVEAATDDVEWYLEFYCKPEDYFAKKY
                     NTNPVHSEVLEAMQTVKQGKALDLGCGQGRNSLFLAQQDFDVTAVDQNGLALEILQSI
                     VEQEDLDMPVGLYDINSASIEQEYDFIVSTVVLMFLQADRIPAIIQNMQEKTSVGGYN
                     LIVCAMDTEDYPCSVNFPFTFKEGELADYYKDWELVKYNENPGHLHRRDENGNRIQLR
                     FATLLAKKIK"
     gene            30576..>31170
                     /gene="coiA"
                     /locus_tag="VQU30_000954"
     CDS             30576..>31170
                     /gene="coiA"
                     /locus_tag="VQU30_000954"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000495911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence protein CoiA"
                     /protein_id="HET2447083.1"
                     /translation="MFVARDARGELVNVLEDKLEKQAYTCPACGGQLHLRQGPSVRTH
                     FAHKSLKDCDFFFENESPEHLANKESLYHWLKKETKVQLEYPLSELKQIADVFVNGNL
                     ALEVQCSPLPQKVLKERSEGYRSQGYQVLWLLGQKLWLKERLTRLQQGFLYFSQNMGF
                     YVWELDKEKQVLRLKYLIYQDLRGKLHYQIKEFSYGQG"
BASE COUNT         9247 a         5778 c         7131 g         9014 t
ORIGIN      
        1 attcgctaat tcttttttta gggcgattga tttgtacttc cgtcgcatca atcattaccg
       61 tgtcctcaga actgagagga gttcttgaaa tcgtaacacc acctttgaac aagagttact
      121 tcaacccatt ggctccgacg gagtaagttg ctttcgtgga taccaaaatc agccgcaatt
      181 tcttcataag tgcgatattc tcgcacatat tgaagagtgg ccataagaag gtcttctagg
      241 cttaatttag gttttcgtcc accttttgcg tgtttaagtt gataagctgt ttttaataca
      301 gctaatatct cttcaaaagt cgtgcgctga acaccaacaa gacgcttaaa tcgtgcatca
      361 gttagttgtt tacttgcttc ataattcata gaactactat accatatttt gtttcgcagg
      421 aagtctattg gaaagtaaga aatattggag ctgaggcgat tagaagaaat tgtgagcgtg
      481 gtgctatttt ttcaggtaaa ataaaacatc acgaagattc tcagtttaaa ggagaccact
      541 atgttgaatg ttatgctgtt ttagataata cggttatagc aagagataga ataacagtcc
      601 ctatcgatcc gttatgtgga aaagatttta tagagtagca tataattgat tcttaactgg
      661 aatactctct atctctttac atcaagaaaa tgactaaaca gggaagtttg ccttcttccc
      721 tttttttgtt atactagtag aagaaaaaaa tagaaagatt tgtgggagtg aaaaagtccg
      781 ggggactttt tcagcttgag ccaagaaatt cgagagcgag gaaagtccgg gggacttttt
      841 cagcctgagc caagaaattc gagagcgaag taagtccaat ggactttttc agcctgagcc
      901 aagaaactcg aaagctcgta agtctgattg gctttttcaa tgtgaatctt aacttcacac
      961 tcccaaagag gtattagtgt cgtgtctcaa tcttatatca atgttatcgg tgctggtttg
     1021 gcaggttctg aagcagctta ccaaatcgca gagcgtggta ttccagttaa actatatgaa
     1081 atgcgtggtg tcaagtcgac tccccagcat aaaacagaca attttgctga gttggtttgt
     1141 tccaattctt tgcgtgggga tgctttgaca aatgcagttg gtcttctcaa ggaagaaatg
     1201 cgtcgcttgg gttctgttat cttggaatct gctgaggcta cacgtgttcc tgcaggtggt
     1261 gcccttgcag tggaccgtga tggtttctct caaatggtga ccgaaaaagt tgccaaccac
     1321 cccttgattg aagtggttcg tgatgaaatt acagaattgc cgacagatgt tattacggtt
     1381 atcgctactg gtcctttgac aagtgatgcc ttggctgaaa agattcatgc ccttaatgac
     1441 ggtgatggtt tttatttcta cgatgcggca gcgcctatta tcgatgtcaa cactatcgat
     1501 atgagcaagg tctacctcaa atcacgttat gataagggag aagcggccta cctcaatgcc
     1561 cctatgacca agcaagaatt tatggatttc catgaagctt tggtcaatgc agaagaagca
     1621 ccgcttaatt cttttgaaaa agaaaagtac tttgaaggct gtatgcctat cgaagtcatg
     1681 gccaaacgtg gcattaaaac tatgctttat ggccctatga agccagtcgg tcttgagtac
     1741 ccagacgact atacaggacc tcgtgatgga gaatttaaaa caccttatgc ggttgtgcaa
     1801 cttcgtcagg acaatgcagc tggtagcctc tacaatattg ttggtttcca gacccacctc
     1861 aaatggggag aacaaaagcg tatcttccaa atgattccgg gtcttgaaaa tgcagagttt
     1921 gtccgttatg gtgtcatgca tcgcaattct tacatggatt caccaaatct tcttgagcag
     1981 acttaccgtt ctaagaaaca accaaatctc ttctttgctg gtcagatgac gggggtggaa
     2041 ggctatgttg agtcggcggc ttcaggctta gttgcgggaa ttaacgcagc tcgtctcttc
     2101 aaggaagaaa gcgaggctat tttccccgag acgacagcga ttggaagctt agctcattac
     2161 attacccatg ccgacagcaa acatttccaa ccaatgaatg tcaattttgg gatcatcaag
     2221 gagttggaag gcgagcgtat ccgtgataag aaggctcgtt atgaaaaaat tgcagagcgt
     2281 gcccttgccg acttagagga atttttgact gtctaatttt tttgaaagaa ttgctcatga
     2341 tactataaaa atcttagaaa ttgtgataaa ataggtagga tgaaagaagg agagtgaaaa
     2401 tggcgaatcc caagtataaa cgtattttaa tcaagttatc aggtgaagcc cttgccggtg
     2461 aacgtggcgt agggattgat atccaaacag ttcaaacaat cgcaaaagag attcaagaag
     2521 ttcatagctt aggtatcgaa attgcccttg ttattggtgg aggaaatctc tggcgtggag
     2581 aacctgcagc agaagcaggt atggaccgtg ttcaggcaga ttacactgga atgcttggga
     2641 ctgttatgaa tgctcttgtg atggcagatt cattgcaaca agttggggtt gatacgcgtg
     2701 tacaaacagc tattgctatg caacaagtgg cagagcctta tgtccgtgga cgtgcccttc
     2761 gtcaccttga aaaaggccgt atcgttatct ttggtgctgg aattggttca ccatacttct
     2821 cgacagatac aacagcggcc cttcgtgcag ctgaaatcga agcggatgcc atcctcatgg
     2881 ctaaaaatgg tgtcgatggt gtttacaatg ccgatcctaa gaaagataag acagctgtta
     2941 agtttgaaga attgacccac cgtgacgtta tcaataaagg tcttcgtatc atggactcaa
     3001 cagcttcaac cctctcaatg gacaacgaca ttgacttggt tgtcttcaac atgaaccaat
     3061 caggcaacat caaacgtgtc gtatttggtg aaaatatcgg aacaacagtt tcaaataata
     3121 tcgaagaaaa ggaataagaa agaatatggc taacgcaatt attgaaaaag ctaaagagag
     3181 aatgacccag tctcaccaat cacttgctcg tgaatttggt ggtatccgtg ctggtcgtgc
     3241 caatgcaagc ttgcttgacc gtatacatgt agaatactat ggagttgaaa ctcctcttaa
     3301 ccaaatcgct tcaattacga ttccagaagc gcgtgttttg ttggtaacac catttgacaa
     3361 gtcttcattg aaagacatcg aacgtgcctt gaacgcttct gatcttggta tcacaccagc
     3421 taatgacggt tctgtgattc gcttggttgt cccagctctt acagaagaga ctcgtcgtga
     3481 ccttgctaaa gaagtgaaga aggtcggcga aaatgctaaa gtggctgtcc gcaatatccg
     3541 tcgcgatgct atggacgaag ctaagaaaca agaaaaagca aaagaaatca ctgaagacga
     3601 attgaagact cttgaaaaag acattcaaaa agtaacagac gatgctgtta aacacatcga
     3661 cgatatgact gccaacaaag agaaagaact tttggaagtc taaaaataaa cagaaaaact
     3721 cagttggcat tgctggctga gttttattcg aaagaaggaa atatgaatac aaatcttgca
     3781 agttttatcg ttggactgat catcgatgaa aacgaccgtt tttactttgt gcaaaaggat
     3841 ggtcaaacct atgctcttgc taaggaagaa ggccaacata cagtagggga tacggtcaaa
     3901 ggttttgcat acacggatat gaagcaaaaa ctccgcctga caagcttaga agtgactgcc
     3961 actcaggacc aatttggttg gggacgtgtc acagaggttc gtaaggactt gggtgtcttt
     4021 gtggatacag gccttcctga caaggaaatc gttgtgtcac tcgatattct ccctgagctc
     4081 aaggaactct ggcctaagaa gggcgaccaa ctctacatcc gtcttgaagt ggataagaaa
     4141 gaccgtatct ggggtctctt ggcttatcaa gaagacttcc aacgtcttgc tcgtcctgcc
     4201 tacaacaaca tgcagaacca aaactggcca gccattgttt accgtctcaa gctatcagga
     4261 acttttgttt acctaccaga aaataatatg cttggtttta ttcatcctag cgagcgttac
     4321 gcagagccac gtttggggca agtattagat gcgcgcgtta ttggtttccg tgaagtggac
     4381 cgcactttga acctctccct caaaccacgc tcctttgaaa tgttggaaaa cgatgctcag
     4441 atgattttga cttatttgga aagcaatggc ggtttcatga ccttaaatga caagtcatct
     4501 ccagacgaca tcaaggcaac ctttggcatt tctaaaggtc agttcaagaa agctttaggt
     4561 ggtcttatga aggctggtaa aatcaagcag gaccagtttg gtacagagtt gatttaggga
     4621 ggcttatgag aaaatcattt tacacttggc tcatgaccga gcgcaatcct aaaagtaaca
     4681 atcccaaagc aattttggca gacctcgctt ttgaagaggc agcttttcca aaacatacag
     4741 atgattttga tgaggtcagt cgctttttgg aggagcatgc cagtttctct tttaacctag
     4801 gagattttga cagcatttgg caggaatatc tagaacacta gcatttattc attgggtttg
     4861 ggctagtaat ttctccatcc ctctgctata ataaaaagaa ataaaaggat tagagaggtt
     4921 ctttatttga aggaacattc aatagacatt caactgagtc atccagatga cctgtttcat
     4981 ctttttggtt ccaatgaacg ccatcttcgt ttgatggaag aagagcttga tgttgtgatt
     5041 catgctcgta cggagattgt ccaggttttg ggagaagagt ctgcttgcga ggaagcccgt
     5101 caggttattc aagctctcat ggccttggta aatcgtggga tgaccgttgg tacgccagat
     5161 gtagtgacgg ctattagtat ggtcaaaaat gatgaaattg acaagtttgt cgccctttac
     5221 gaagaagaaa tcatcaagga taatactggg aagcctatcc gcgtcaaaac cttaggtcaa
     5281 aaactttatg tggacagtgt caaacagcat gatgtgacct ttggaattgg gccagcaggt
     5341 acagggaaga ccttccttgc agtgaccttg gcagtgactg cccttaaacg tgggcaagtc
     5401 aagcgaatta tcctaactcg tccagcggtg gaagcgggag agagtcttgg atttcttccg
     5461 ggtgatctta aggagaaggt ggatccttac cttcgtcctg tttacgatgc cttgtatcaa
     5521 attcttggga aagaccaaac gactcgtctc atggagcgtg aaattatcga aattgcgccc
     5581 cttgcctata tgcgtggccg gaccttggat gatgcctttg tcattctcga tgaggcgcaa
     5641 aacacgacca tcatgcagat gaagatgttc ttgacgcgtt taggctttca ttctaagatg
     5701 attgtcaatg gagatatcag tcagattgac ctgccacgta atgtcaagtc cggtttgatt
     5761 gatgctcaag agaaactcaa gaacatccat cagattgact ttgttcattt ttcagccaag
     5821 gatgtggttc gccatccagt tgtcgctcag attatccgag cctatgaata ttctactgaa
     5881 gttgcacacg actgattttg aggaagttcg cctgcaaaag aatatacttt tgagagagga
     5941 aaatccagtt gtataggcta aaggtttgag acaacgatta ggcacgatgg aaagaacttt
     6001 tatgtggctg atgacgatca gtgcatcttc ctgtgtcata atcacagggc acaagaaagt
     6061 aggaatttga aaagatgatt gaccaactat ctaagtatta cagttgtagg atactaactg
     6121 aaaaggatat tccaagtatt ttatctttat atgaaagtaa tcctctgtat tttcagcatt
     6181 gtccaccaga gccaaatttt gcaactgtaa aagaggacat gctttgtcta cctgaaggta
     6241 aagctaaggc tgataagttt tttgttggat tttggaatgg ctctgacctt gtggctgtta
     6301 tggattttgt ctatgcatat cctgatgagg agactgtttt tattggtttg tttatggttg
     6361 atcaagccta tcagaggaaa gggattggta gtcatattgt gacagaagca ctagcttatt
     6421 ttgctaagaa ctttcgaaag gcacgtttgg cttatgttaa gggaaatccg caatctcagc
     6481 atttttggga aaagcagggc tttaaatcaa ttggatgcga ggttaagcaa gaactctata
     6541 cggttgttat cgctgaacag agcctagaag attagaaatg gcatcaagta agaactattt
     6601 ggaatttgtt ttggaacaat tatcaggatt agatgatgtg acttaccgtt ccatgattgg
     6661 ggagtatatt ctttacttcc gcggcaagat tattggcggc atttatgacg atcgcttttt
     6721 agttaaaccc gtgcaagcag tcttagataa gattgaccaa tcttcttttg agtttccata
     6781 caaaggtgcc aaagaaatga tttgagtgga agaacttgat aataagatgt ttctataaga
     6841 cctgatttta gctatgtata accaactgcc aacgcccaaa cctaaaaaga aaaagcaagg
     6901 gtgaacgaag taaaaaagaa gtctgctaag gccctgtctt tgcacgggta aaattttata
     6961 tataaaaaga agctgggact aaagagctca gcttcctttg gtttatataa ttgtcattac
     7021 aagacgaagt ggttgggcga aactctgttg actttattca atttagagtt tcttatgcac
     7081 aattgagtct ggaacgaaag tctccagttg caaagtatac agtacaataa accaacgatg
     7141 taatagctga tgacacaaag cacagtgggt aggacttgcg aagtcaccct tttcttttca
     7201 aaatttatac taaatcattg atatcagtgt agtcacgatt aagtccttga gcaactggta
     7261 ggctagtcaa gtaaccttga taagtggtca caccttgacg caagccttca tcttcagaga
     7321 ttgcttgtgc gaatcctttg ccagccaaag cttcgatata aggaagagtg acattggtta
     7381 gggcgatggt tgaagtgcgg gcaaccgcac cagggatatt ggcaacggca tagtggagaa
     7441 caccgtgttt ttcatagacg ggttcatcgt gcgttgtcac acggtcagct gtttcgataa
     7501 cgccaccttg gtcaacagca acgtcaacga tacagagcct ggacgcattt gtttgaccat
     7561 ctcatctgtc accaattccg gtgcttttgc accagggatg agaatggctc caatcaccac
     7621 atcagcatct ctcacacttg cttcaatgtt gaatgaatta gatataatag tttgaatttg
     7681 acttccaaag acttcttcta gaactgagag acgcttggca ctaatatcta aaatagtcac
     7741 ttgagcacca agaccaaggg cgatgcgggc agcatgtgta ccgacgacac catcaccgat
     7801 gatagttact tttccttttg gaacacctgg tacaccacca agtagaacac cagagccacc
     7861 agcttgctta gtaaggaagt gagctccgat ttgaacagcc atacgacctg caacctcact
     7921 cataggaacg aggagcggta gttgtccttg attgtcacga acagtttcat aggcaattcc
     7981 tgttgttttt gctgctaaca tagcatctgc taattctgga gcagcggcca tgtgcaagta
     8041 ggtgaagaga agaagatcgt cgcgcaagta accgtattca gaacttaaag gttcttttac
     8101 tttcacaacc aactctgctg cccaagcttc accagcagta gcgacaatct cagctccttg
     8161 cttttgatag tcagcatcag taaagccaga accgagacca gcatttgttt cgataaggac
     8221 acgatgacca cgactaacta agctatgaac acctgcaggt gtgagggcga cacggttttc
     8281 gttattttta atttcttttg ggattccgat taacattgag ataacctacc tttcaattga
     8341 cggtcttgtt ttggttgtca cattccagtt cataaatcaa aaatgtgacg gtttcattgt
     8401 atatgaaacc gcttcaaaaa tcaagaaaaa cttgtcatcc aaattttttt atgctagact
     8461 agtgaaaatc aagctctaat ggagggaaaa gtatggaatc aatatttgtg aaatttgccc
     8521 agtatccgtc tatagaaacg gagcgtttat tgcttagacc tgtaactttg gatgatgcgg
     8581 aagcaatgtt tgactatgcc tcggacaagg gtaatacacg ttacactttt ccaaccaatc
     8641 aaagcttgga agaaaccaag aataacattg ctcagttcta cttggctaat cccttgggac
     8701 gttgggggat tgaattaaaa gataacggca agtttatcgg aactattgac ttacacaaga
     8761 ttgatcctgt tcttaagaag gcagctattg gctacattat caataaaaag tattggaatc
     8821 aaggattaac gacagaagcc aatcgtgctg tgattgagct agcttttgag aagataggga
     8881 tgaataagtt gactgccctt cacgataagg ctaatcccgc gtcaggaaag gtcatggaga
     8941 aatcaggcat gcgtttttcc catgcagaac catatgcttg tatggaccag catgaaaaag
     9001 gccgaatcgt gacaagagtt cattatgtct tgaccaagga agactatttt gcaaataaat
     9061 aagcagttga aaagaaattt ttcgactgtt ttttcttcct cttacgaata atctaagaga
     9121 ggagaaaata tggaagcaat tatcgagaaa atcaaagagt ataaaatcat cgtcatctgt
     9181 actggtctgg gcttgcttgt aggaggattt ttcctgctaa agccagctcc acaaacatct
     9241 gtcaaagaga cgaatttgca ggctgaagtt gcagctgttt ccaaggactc atcgaccgga
     9301 aaggaagtga acaaggaaga gaaggaagaa ccagttgaac aagatctaat cacagtagat
     9361 gtcaaaggtg ctgtcaaatc gccagggatt tatgacttgc ctgtaggtag tcgagtcaat
     9421 gatgctgttc agaaggctgg tggcttgaca gagcaagcag acagcaagtc gctcaatcta
     9481 gctcagaaag ttagtgatga ggctctggtt tacgttccta ctaagggaga agaagcagtt
     9541 agtcaacaga ctggttcggg gacagcttct tcaacaagca aggaaaagaa ggtcaatctc
     9601 aacaaggcca gtctggaaga actcaagcag gtcaagggac tgggaggaaa acgagctcag
     9661 gacattattg accatcgtga ggcaaatggc aagttcaagt cagtagacga gctcaagaag
     9721 gtctctggca ttggtgccaa gaccatagaa aaacttaaag actatgttac agtggattaa
     9781 gaatttctct attcccctaa tttacctgag ttttctatta ctatggcttt actacgccat
     9841 tttctcagta tcctattttg ctttgttggg ttttgttttt ctgctagtct gcctctttat
     9901 ccaatttcct tggaaatcag caggtaaagt tctagtgatt tgtggagtct ttggcttctg
     9961 gtttctgttt caaacttggc aacagagtca agtgagtcaa aatttggtgg attctgttga
    10021 aagggtacgg attttaccag acactattaa ggttaacggt gacagtctgt cctttcgtgg
    10081 taagtctgat ggtcgtgctt tccaagtcta ttataaactc cagtccgagg aggagaaaga
    10141 agcctttcaa gctttaactg accttcatga gataggacta gaagggaagc tttcggagcc
    10201 agaagggcag agaaattttg gtggctttga ctaccaaggc tatctgaaga ctcagggaat
    10261 ttaccagaca ctcaatatta aaagaatcca gtcactccaa aaggttggca gttgggatat
    10321 aggtgaaaac ctgtccagtt tacgtcgaaa ggctgtggtt tggattaaga tgcacttccc
    10381 agaccctatg cgcaattaca tgacaggact cttgctagga catctggaca ccgattttga
    10441 ggagatgaat gagctttatt ccagtttagg aattattcac ctttttgcct tgtcaggtat
    10501 gcaggtaggg tttttcatgg acggatttaa gaaactactt ttacgattgg gcttgacaca
    10561 agaaaagttg aagtggctga cttatccctt ttcccttatc tatgcgggac taactggatt
    10621 ttcagcatcg gttattcgca gtctcttgca aaagctactg gctcaacatg gggttaaggg
    10681 cttggataat tttgccttga cggtgcttgt cctctttatt gtcatgccaa actttttctt
    10741 gacagcagga ggagtcttgt cctgtgctta tgcttttatc ctgaccatga ccagcaaaga
    10801 aggggagggg ctcaaggctg ttactagtga aagtctagtc atctccttgg gcatattgcc
    10861 cattctatcc ttctattttg cggaatttca accttggtct atccttttga cctttgtctt
    10921 ttcctttctt tttgacttgg tcttcttacc gctcttgtct atcttatttg tcctttcctt
    10981 tctctatcca gtcattcagc tgaactttat ctttgaatgg ttagagggca ttattcgctt
    11041 ggtctcgcag gtggcaagta gaccgcttgt ctttggacaa cccaatgaat ggcttttaat
    11101 cctattgtta atttctttgg ctttggtcta tgatttgagg aaaaacatta aaaagctaac
    11161 ggtattgtgc ttattgatta cagggctctt tctcctgacc aagcatccac tggaaaatga
    11221 aatcaccatg ctggatgtgg ggcaaggaga aagtattttc ctacgggatg taactgggaa
    11281 aaccattctc atagatgtag gtggtaaggc agaatcttat aagaaaatca aaaaatggca
    11341 agaaaagatg acgaccagca atgcccagcg aagcttgata ccctatctca aaagtcgagg
    11401 agtagctaag attgaccagc taattttgac taacacggac aaggagcatg ttggagattt
    11461 gtcagagatg accaaggctt tccatgtagg ggagattcta gtatcaaaag acagtctgaa
    11521 acagaaggaa tttgtggcag aactacaggc gactcaaaca aaggtgcgta gtatgatagt
    11581 aggggagaac ttacccattt ttggaagtca gttagaagtt ctatctccaa ggaaaatggg
    11641 agatggagga cacgatgata ccctagttct gtatgggaaa ttcttggata agcaatttct
    11701 cttcacggga aatttggagg agaaaggaga gaaggacttg ctgaagcact atccagactt
    11761 gaaagtaaat gttttgaaag ctagccaaca tggcaataaa aaatcatcaa gtccagcctt
    11821 tctagaaaaa ctcaaaccag agcttactct tatctcagtt ggaaagagca atcgaatgaa
    11881 actcccccat caggaaacat tgacacgact ggaaggtatc aatagcaaag tttatcgaac
    11941 tgaccagcaa ggagctatac gttttaaggg gttggatagt tggaaaatcg aaagtgttcg
    12001 ataggaagga taaatgttgt agattagtga aataaactaa aaatttgttg cataataatg
    12061 ataaaaacgg cataatgaaa acgtattcaa tattgaggat ataaaatcat taaaaatcag
    12121 caaaagttgt tttagttagt tagtttataa tctattggtc ttcttcagtc cagtgtatct
    12181 gctgtgacag tcactaaaag ttacaagtat gattggaata cggttttgga atatagtacc
    12241 aactatcacg accatcagta tgcttggatt ccggaatggt ctcgttatta cagctattct
    12301 gagtataaag ttggcggagg ctggaactac gctcgttatg aggtcataaa ctactatact
    12361 ggaggttatt aatccttaaa gagtgagaaa aggagggctg gatatgttaa atcttactca
    12421 tgttacctta aaaacgcgac aagtcatctt gcaagatgcg gattttacct ttaaaaaggg
    12481 taggatttat ggccttcttg ctatcaatgg ctcgggaaag acgacactat tccgagctat
    12541 gagcaagttg cttcccctta gtagtggaca catcgcagtt cctccttctt tgttttatta
    12601 tgagagcgtt gaatggctgg atggaaactt aagtgggatg gactaccttc gtctcataaa
    12661 aaacatctgg aagtcagacc taaacttgag agatgaaatc gcctactggg aaatggctga
    12721 ctatatcagt cttcccatcc gcaagtattc cttagggatg aagcaacgct tggtgattgc
    12781 tatgtatttt ctcagtcagg ccaaatgctg gctcatggat gagattacaa atggcttaga
    12841 cgagtattat cgacagaagt tttttgatag gctagcacaa atcgatagac aagaacagct
    12901 ggttctttta agttcccact ataaggaaga gttggttgat atctgcgata gagtagtaac
    12961 cattcatcag gggcagatag aagaggttta gtttatgaaa gatgttagtc tatttttatt
    13021 gaaaaaagtt ttcaaaagtc gtttaaactg gattatctta gctttatttg tatctgtact
    13081 cggtgttacc ttttatttaa atagtcagac tgcaaactca cacagcttgg agagcaggtt
    13141 ggaaagtcgc attgcagcca acgagagggc tatcaatgaa aatgaagaga aactctccca
    13201 aatgtctgat accagctcgg aggaatacca gtttgctaaa aataatttag acgtgcaaaa
    13261 aaatcttttg acgcgaaaga cagaaattct aactttacta aaagaagggc gctggaaaga
    13321 agcctactat ctgcagtgga aagatgaaga gaagaattat gaatttgtat caaatgaccc
    13381 gactgctagc tctggcttaa aaatgggggt tgaccgcgaa cggaagattt accaagccct
    13441 gtatcccttg aacataaaag cacatacttt ggagtttccg acccacggga ttgatcagat
    13501 tgtctggatt ttagaggtta tcatcccaag cttgtttgtg gttgcgatta tttttatgct
    13561 aacacaacta tttgcagaaa gatatcaaaa tcatctggac acagctcact tatatcctgt
    13621 ttcaaaagtg acatttgcaa tatcctctct tggagttgga gtgggatatg taactgtgct
    13681 gtttatcgga atctgtggct tttcttttct agtgggaagt ctgataagtg gttttggaca
    13741 gttagattat ccctacccaa tttatagctt agtgaatcaa gaagtaacta ttgggaaaat
    13801 acaagatgta ttatttcctg gcttgctctt agctttctta gcctttatcg tcattgtgga
    13861 agttgtgtac ttgattgctt actttttcaa gcaaaaaatg cctgtcctct ttctttcact
    13921 cattgggatt gttggcttat tgtttggcat ccaaacaatt cagcctcttc aaaggattgc
    13981 acatctgatt ccctttactt acttgcgttc agtggagatt ttatctggaa gattacctaa
    14041 gcagattgat aatgtcgatc taaattggag catgggaatg gtcttacttc cttgcctgat
    14101 tatctttttg ctattgggaa ttctatttat tgaaagatgg ggaagttcac agaaaaaaag
    14161 aattttttaa tagattctag ctttcctata ggtagggaaa ataagtaaaa actaacatag
    14221 agagggaatc aacttgattc tctctttttg attcgaaaac caaaccaaaa tacaaacaca
    14281 aacttttcaa aaaataactt tttatcttga caagagctag aaaacttggt atcatataaa
    14341 agttgagaaa agcagaagtg agagcttctc gccttgtgac attaagttgc ctggccctac
    14401 ggatgaaaag tttcgaagaa acgctatcat aacgtgcggg cttgtatatt tacgagtccg
    14461 ctattgtttt tctctaataa aacaaaagag gtgaaaacca tagcaaagca agacttattc
    14521 atcaatgatg agattcgtgt acgtgaagtt cgcttgattg gtcttgaagg agaacagcta
    14581 ggcatcaagc cactcagtga agcgcaagct ttggctgata acgctaatgt tgacctagta
    14641 ttgattcaac cccaagccaa accgcctgtt gcaaaaatta tggactacgg taagttcaaa
    14701 tttgagtacc agaagaagca aaaagaacaa cgtaaaaaac aaagcgttgt tactgtgaaa
    14761 gaagttcgtc taagtccaac tattgacaag ggtgactttg atacaaaact tcgtaatgca
    14821 cgtaagttcc ttgaaaaagg aaataaagtt aaggtatcta ttcgctttaa gggtcgtatg
    14881 attacccata aagagattgg tgcaaaagtt ttagccgagt ttgctgaagc aactcaagat
    14941 attgccatca tcgaacaacg tgctaaaatg gatggacgtc aaatgttcat gcaattggcg
    15001 ccagcgactg acaaaaaata attgtcagaa agttaaataa aggagaaaaa attatgccaa
    15061 aacaaaaaac acaccgcgca tcagctaaac gtttcaaacg tacaggttct ggtggactta
    15121 aacgtttccg tgcttacact tctcaccgtt tccacggaaa aactaagaaa caacgtcgtc
    15181 atcttcgtaa agcatctatg gtgcattcag gagattacaa acgtatcaaa gcaatgctta
    15241 ctcgcttgaa ataatagctt gactgtaagt aaacaattct aggaaatatt tggaggaaat
    15301 aaaacatggc acgtgttaaa ggtggcgttg tatcacgcaa acgtcgtaaa cgtattctta
    15361 aattagcaaa aggttactat ggagctaaac acatcttgtt ccgtactgca aaagaacaag
    15421 taatgaactc ttactactat gcataccgtg accgtcgtca gaaaaaacgt gacttccgca
    15481 aattgtggat cactcgtatc aatgcggcag ctcgtatgaa cggactttca tactcacaat
    15541 tgatgcatgg tttgaaattg gctgagatcg aagttaaccg taaaatgctt gctgacttgg
    15601 ctgttaacga tgcagtagct ttcacagctc ttgcagatgc agctaaagca aaacttggta
    15661 aataacaact gatgagactg gaacaggatt gtccagtctt tttaaaaata aaggagaaaa
    15721 atatggcttc aaaaatgcta cacacttgct tacgagtaga aaatcttgaa aaatcaatcg
    15781 cattttatca agatgctttt ggttttaaag aattgcgtcg cagagatttt ccagaccatg
    15841 ccttcacgat tgtctatcta ggtcttgagg gtgatgacta tgagttggag ttgacttata
    15901 actacgatca cggtccgtat gtggttggtg atgggtttgc ccatatcgcc ctcagtacac
    15961 ctgatcttga ggcacttcat caagaacaca gtgcaaaagg ctatgaagtg actgagccaa
    16021 atggtctacc aggaactaca ccaaactatt actttgtcaa agaccctgat ggatataagg
    16081 tcgaagtcat tcgtgaaaaa taatttcgtg caagttaagt agaatattcg ttttttactt
    16141 gacttttttt agctgaaaga gtatactaat aaaaattcaa cctttaaggg gagtccagag
    16201 agactcacaa ggtgtcagat aaaagaatag tgcaattttc tagaggagac tttttgagtg
    16261 tgctctcttg tgttgtacga ttttaactga ggccttgcac tagcaaggtc ttttctttat
    16321 ctggtcccct taaaatttaa ggaggaaaag ttatgaatcc cacatgtaag aagcgtttgg
    16381 gtgtcattcg gttggaaacc atgaaggtgg ttgcacaaga ggaaatcgcg ccagcaatct
    16441 ttgaattagt cctagaagga gaaatggttg aagccatgcg agcaggccaa tttcttcatc
    16501 tgcgtgtacc agacgatgcc catcttttac gtcgtcctat ttcaatttcg tctattgaca
    16561 aggcaaacaa gcagtgtcac ctcatttatc ggattgaggg agctgggact gcaatttttt
    16621 caaccttaag tcagggagac actcttgatg tgatggggcc tcagggaaat ggttttgact
    16681 tgtctgacct tgatgagcag aatcaggttc tccttgttgg tggtgggatt ggtgttccac
    16741 ccttgcttga ggtggccaag gaattgcatg aacgtggagt gaaagtagtg acagtcctcg
    16801 gttttgctaa taaggatgct gttattttga aaacggaatt ggctcagtat ggtcaggtct
    16861 ttgtaacgac agatgatggt tcttatggca tcaagggaaa tgtttccgtt gttatcaatg
    16921 atttagatag tcagtttgat gctgtttact cgtgtggggc tccaggaatg atgaagtata
    16981 tcaatcaaac ctttgatgat cacccaagag cctatttatc tctggaatct cgtatggctt
    17041 gtgggatggg agcttgctat gcctgtgttc taaaagtacc agaaagcgag acggtcaacc
    17101 aacgcgtctg tgaagatggt cctgttttcc gcacaggaac agttgtatta taaggagaaa
    17161 attatgacta caaatcgatt acaagtgtct ctacctggtt tggatttgaa aaatccgatt
    17221 attccagcat caggttgttt tggctttgga caagagtatg ccaagtacta tgatttaaac
    17281 cttttaggtt ctattatgat caaggcgaca acccttgaac cacgttttgg gaacccaact
    17341 ccaagagtag cagagacgcc tgctggtatg ctcaatgcaa ttggcttgca aaatcctggt
    17401 ttagaggttg ttttggctga aaagctacct tggctggaaa gagaatatcc aaatcttcct
    17461 attattgcca atgtagctgg tttttcaaaa caagagtatg cagctgtttc tcatgggatt
    17521 tccaaggcaa ctaatgtaaa agctatcgag ctcaatattt cttgtcccaa tgttgaccac
    17581 tgtaatcatg gacttttgat tggtcaagat ccagatttgg cttatgatgt ggtgaaagca
    17641 gctgtggaag cctcagaagt gccagtttat gtcaaattaa ccccgagtgt gaccgatatc
    17701 gttactgtcg caaaagctgc agaagatgcg ggagcaagtg gcttgaccat gatcaatact
    17761 ctggttggaa tgcgctttga cctcaaaacc agaaaaccaa tcttggccaa tggaacaggt
    17821 ggaatgtcag gtccagcagt ctttccagta gccctcaaac tcatccgcca agtagcccaa
    17881 acaacagacc tgcctatcat tggaatgggg ggagtggatt cggctgaagc tgccctagaa
    17941 atgtatctgg ctggggcatc tgctatcgga gttggaacag ctaactttac caatccttat
    18001 gcctgccctg acatcatcga aaatttacca aaagtcatgg ataaatacgg tattagcagt
    18061 ctggaagaac tccgtcagga agtaaaagag tctctgaggt aaactgcaat caatctgttc
    18121 ttgatttttt attagtttgt aatatgaatt taggagaatt ttggtacaat aaaataaata
    18181 agaacagagg aagaaggtta atgaagaaag taagatttat ttttttagct ctgctatttt
    18241 tcttagctag tccagagggt gcaatggcta gtgatggtac ttggcaagga aaacagtatc
    18301 tgaaagaaga tggcagtcaa gcagcgaatg agtgggtttt tgatactcat tatcaatctt
    18361 ggttctatat aaaagcagat gctaactatg ctgaaaatga atggctaaag caaggtgacg
    18421 actattttta cctcaaatct ggtggctata tggccaaatc agaatgggta gaagacaagg
    18481 gagcctttta ttatcttgac caagatggaa agatgaaaag aaatgcttgg gtaggaactt
    18541 cctatgttgg tgcaacaggt gccaaagtaa tagaagactg ggtctatgat tctcaatacg
    18601 atgcttggtt ttatatcaaa gcagatggac agcacgcaga gaaagaatgg ctccaaatta
    18661 aagggaagga ctattatttc aaatccggtg gttatctact aacaagtcag tggattaatc
    18721 aagcttatgt gaatgctagt ggtgccaaag tacagcaagg ttggcttttt gacaaacaat
    18781 accaatcttg gttttacata aaagaaaatg gaaactatgc tgataaagaa tggattttcg
    18841 agaatggtca ctattattat ctaaaatctg gtggctacat ggcagccaat gaatggattt
    18901 gggataagga atcttggttt tatctcaaat ttgatgggaa aatagctgaa aaagaatggg
    18961 tctacgattc tcatagtcaa gcctggtact acttcaaatc cggtggttac atgacagcca
    19021 atgaatggat ttgggataag gaatcttggt tttacctcaa gtctgatggc aaaatggctg
    19081 aaaaagaatg ggtctacgat tctcatagtc aagcctggta ctacttcaaa tctggtggtt
    19141 acatggcgaa aaatgagaca gtagatggtt atcagcttgg aagcgatggt aaatggcttg
    19201 gaggaaaagc tacaaatgaa aatgctgctt actatcaagt agtgcctgtt acagccaatg
    19261 tttatgattc agatggtgaa aagctttcct atatatcgca aggtagtgtc gtatggctag
    19321 ataaggatag aaaaagtgat gacaagcgct tggctattac tatttctggt ttgtcaggct
    19381 atatgaaaac agaagattta caagcgctag atgctagtaa ggactttatc ccttattatg
    19441 agagtgatgg ccaccgtttt tatcactatg tggctcagaa tgctagtatc ccagtagctt
    19501 ctcatctttc tgatatggaa gtaggcaaga aatattattc ggcagatggc ctgcattttg
    19561 atggttttaa gcttgagaat cccttccttt tcaaagattt aacagaggct acaaactaca
    19621 gtgctgaaga attggataag gtatttagtt tgctaaacat taacaatagc cttttggaga
    19681 acaagggcgc tacttttaag gaagccgaag aacattacca tatcaatgct ctttatctcc
    19741 ttgcccatag tgccctagaa agtaactggg gaagaagtaa aattgccaaa gataagaata
    19801 atttctttgg cattacagcc tatgatacga ccccttacct ttctgctaag acatttgatg
    19861 atgtggataa gggaatttta ggtgcaacca agtggattaa ggaaaattat atcgataggg
    19921 gaagaacttt ccttggaaac aaggcttctg gtatgaatgt ggaatatgct tcagaccctt
    19981 attggggcga aaaaattgct agtgtgatga tgaaaatcaa tgagaagcta ggtggcaaag
    20041 attagtacta taagtgaata tgatttgagt gaatagtaag ttaaaaatcc tgatttcaag
    20101 taaaatcagg attttttcat ggatgcaatt tttttggagt ctggtgtgac gcggagggtc
    20161 ttttgtcctg tgtaagtgac aaagccgggt tttccaccag ttggtttatt gagttttttg
    20221 acttcaatca tatctacctg caccagattc gacaggcgcc cttgagagaa gtaggcagct
    20281 aactctgctg cgtctgtctt gactgcatca gatgggtcaa gatttcctga gatgacaaca
    20341 tggcttccag gaatgtcctt agcatggaac caaagttcct ccttgcgggc cattttaaag
    20401 gtcaattcct cattttgaag attgtttcgt ccgacataga tgatggtttt gccatcgctt
    20461 gctagatatt gttctagttt tttgcgtttc tggattttct cccgttgtct tctgcggata
    20521 aaacctgttt gaatcaattc ttcacggatt tcagcgattt cttccagtcc agcttggttg
    20581 aggacggttt ctacactttc cagatagaga atagtggctt tggtttcttc aatcaaatca
    20641 gtcaagtatt tgacagcttc tttgagtttc tgataccgtt taaaatagcg ttgggcattc
    20701 tggttgggag tcagagcctt atcaagcgca atcatgatag gttggttggt atagtagttg
    20761 tctaggataa cctggtcttg gtcgttaggc acttggtgga ggaaggttgt cagcaattct
    20821 cctttttgac gaaattcttc agcgttgtct gtcgccagta actctttttc ctgttttttg
    20881 agtttgtgtc ggtttttctg aagttcattt tcaacacgac gaatcagttc actggcctgc
    20941 tgtttgacgc ggtcgcgctc agccttatcc ttatagtagg tgtccaacaa atcagaaaga
    21001 tttgcaagag gctctcccac ctgatttgca aaaggaactg gactgaagga agtctcagtc
    21061 aagcatggct tggtttcttg attgaaaaaa tttcggaaag cggaaagttt ttcactaacc
    21121 agtatccttt ccaattcatt tgccgtatcg cgtcccagac cttgaaagag gctttgaaga
    21181 ttttttgctg ttagttcttg ggtttgcagg atttcaaaga gcttttcatc cttgatagta
    21241 aaaggattga gagattttgt acttggcgga gcgatatagg tcgatcctgg aagtaaggtg
    21301 cggtagctat tttgtgaaaa gccgacgtgt ttgataactt cgaggatttt atgactgctt
    21361 ttatcgacca gtagaatatt actgtgtttc cccataattt cgataatcaa ggtagcctgg
    21421 atatggtctc caatctcgtt tttattggaa actgtaattt ccacaatacg gtcattttcc
    21481 acttgctcaa tcgactcaat cagggccccc tgcaaatact ttctcaaaac catgataaag
    21541 gtagaaggtt gggctggatt ttcaaaagtc gtttgggtca gctgaatgcg tccaaaaact
    21601 ggatgggcag aaaggagcag gcgatggctt tggcgattgc tgcggatttg caagaccaac
    21661 tcttgttcaa aaggctgatt gattttctgg atgcgaccat tcactaattc gcttcgcaat
    21721 tcctcaacta tgtggtgtaa aaaaaatccg tcaaatgaca tcgttctctc cttgtgattg
    21781 tattccatag tattatatca aaaaggtaga ataaaatcat ggaaatgtgg tataataaag
    21841 ccaagtaaag agaaacgaga agcacatgta tattgaaatg gtagatgaaa ctggtcaagt
    21901 ttcaaaagaa atgttgcaac aaacccaaga aattttggaa tttgcagccc aaaaattagg
    21961 aaaagaagac aaggagatgg cagtcacttt tgtgaccaat gagcgtagtc atgaacttaa
    22021 tctggggtac cgtgacaccg accgtccgac agatgtcatc agccttgagt ataaaccaga
    22081 attggaaatt gcctttgacg aagaggattt gcttgaaaat ccagaattgg cagagatgat
    22141 gtctgagttt gatgcctata ttggggaatt gttcatctct atcgataagg ctcatgagca
    22201 ggccgaagaa tatggtcaca gctttgagcg tgagatgggc ttcttggcag tacacggctt
    22261 tttacatatt aacggctatg atcactatac tccggaagaa gaagcggaga tgttcggttt
    22321 acaagaagaa attttgacag cctatggact cacaagacaa taaacgaaaa tggaaaaatc
    22381 gtgacctgat atccagttta gaatttgcca tcacagggat ttttactgct atcaaggaag
    22441 aacgcaatat gcgaaaacat gcagtgacgg ctctagtggt catccttgca ggttttggtt
    22501 ttcaggtgtc acgaatcgaa tggctctttc tcctattgag cattttcttg gtggtagcct
    22561 ttgaaattat caattctgct atcgaaaatg tggtggattt ggccagtcac tatcactttt
    22621 ccatgctggc taaaaatgcc aaggatatgg cggctggcgc ggtattagtg gtttctcttt
    22681 ttgcagcctt aacaggcgca ttgatttttc tcccacgaat ctgggattta ttattttaaa
    22741 cagtaagagg aaattatgac ttttaaatca ggctttgtag ccattttagg acgtcccaat
    22801 gttgggaagt caaccttttt aaatcacgtt atggggcaaa agattgccat catgagtgac
    22861 aaggcgcaga caacgcgcaa taaaatcatg ggaatttaca cgactgataa ggagcaaatt
    22921 gtctttatcg acacaccagg gattcacaaa cctaaaacag ctctcggaga tttcatggtt
    22981 gagtctgcct acagtaccct tcgcgaagtg gacactgttc ttttcatggt gcctgctgat
    23041 gaagcgcgtg gtaaggggga cgatatgatt atcgagcgtc tcaaggctgc caaggttcct
    23101 gtgattttgg tggtgaataa aatcgataag gtccatccag accagctctt gtctcagatt
    23161 gatgacttcc gtaatcaaat ggactttaag gaaattgttc caatctcagc ccttcaggga
    23221 aataacgtgt ctcgtctagt ggatattttg agtgaaaatc tggatgaagg tttccaatat
    23281 ttcccgtctg atcaaatcac agaccatcca gaccgtttct tagtttcaga aatggttcgc
    23341 gagaaagtct tgcacctaac tcgtgaagag attccgcatt ctgtagcagt agttgttgac
    23401 tctatgaaac gagacgaaga gacagacaag gttcacatcc gtgcaaccat catggtcgag
    23461 cgcgatagcc aaaaagggat tatcatcggt aaaggtggcg ctatgcttaa gaaaatcggt
    23521 agcatggccc gtcgtgatat cgaactcatg ctaggagaca aggtcttcct agaaacctgg
    23581 gtcaaggtca agaaaaactg gcgcgataaa aagctagatt tggctgactt tggctataat
    23641 gaaagagaat actaagtaga ggtgggctca tgcctgcttc ttgtttttac agaaggagga
    23701 cttatgcctg aattacctga ggttgaaacc gtttgtcgtt gcttagaaaa attgattata
    23761 ggaaagaaga tttcgagtat agaaattcgc taccccaaga tgattaagac ggatttggaa
    23821 gagtttcaaa gggaattgcc tagtcagatt atcgagtcaa tgggacgtcg tggaaaatat
    23881 ttgctttttt atctgacaga caaggttttg atttcccatt tgcggatgga gggcaagtat
    23941 ttttactatc cagaccaagg acctgaacgc aagcatgccc atgttttctt tcattttgaa
    24001 gatggtggca cgcttgttta tgaggatgtt cgcaagtttg gaaccatgga actcttggtg
    24061 cctgaccttt tagacgccta ctttatttct aaaaaattag gtcctgaacc aagcgaacaa
    24121 gactttgatt tacaggtctt tcaatctgcc cttgccaagt ccaaaaagcc tatcaaatcc
    24181 catctcctag accagacctt ggtagctgga cttggcaata tctatgtgga tgaggttctc
    24241 tggcgagctc aggttcatcc agctagatct tcccagactt tgacagcaga agaagcgaca
    24301 gctattcatg accaaaccat tgctgttttg agccaggctg ttgaaaaagg cggttccacc
    24361 attcggacct ataccaatgc ctttggggaa gatggaagca tgcaggattt tcatcaggtc
    24421 tatgataaga ctggtcaagg atgtgtacgc tgtggtacca tcattgagaa aattcaacta
    24481 ggtggacgtg gaacccactt ttgtccaaac tgtcaaagga gggactgatg ggaaaaatca
    24541 tcggaatcac tgggggaatt gcctctggta agtcaactgt gacaaatttt ctaagacagc
    24601 aaggctttca agtagtggat gccgacgcag tcgtccacca actacagaaa cctggtggtc
    24661 gtctgtttga ggctctagta cagcactttt ggcaagaaat cattcttgaa aacggagaac
    24721 tcaatcgccc tctcctagct agtctcatct tttcaaatcc tgatgaacga gaatggtcta
    24781 agcaaattca aggggagatt atccgtgagg aactggctac tttgagagaa cagttggctc
    24841 agacagaaga gattttcttc atggatattc ccctactttt tgagcaggac tacagcgatt
    24901 ggtttgctga gacttggttg gtctatgtgg accgagatgc ccaagtagaa cgcttaatga
    24961 aaagggacca gttgtccaaa gatgaagctg agtctcgtct ggcagcccag tggcctttag
    25021 aaaaaaagaa agatttggcc agccaggttc ttgataataa tggcaatcag aaccagcttc
    25081 ttaatcaagt gcatatcctt cttgagggag gtaggcaaga tgacagagat taactggaag
    25141 gataatctgc gcattgcctg gtttggtaat tttctgacag gagccagtat ttctttggtt
    25201 gtacctttta tgcctatctt cgtggaaaat ctaggtgtag ggagtgagca agtcgctttt
    25261 tatgcaggct tagcaatttc tgtctctgct atttccgcgg cgctcttttc tcctatttgg
    25321 ggtattcttg ctgacaaata cggccgaaaa cccatgatga ttcgggcagg tcttgctatg
    25381 actatcacta tgggaggctt ggcctttgtc ccaaatatct attggttaat ctttcttcgt
    25441 ttactaaacg gtgtatttgc aggttttgtt cctaatgcaa cggcactgat agccagtcag
    25501 gttccaaagg agaaatcagg ctctgcctta ggtactttgt ctacaggcgt agttgcaggt
    25561 actctaactg gtccctttat tggtggcttt atcgcagaat tatttggcat tcgtacagtt
    25621 ttcttactgg ttggtagttt tctattttta gctgctattt tgactatttg ctttatcaag
    25681 gaagattttc aaccagtagc caaggaaaag gctattccaa caaaggaatt atttacctcg
    25741 gttaaatatc cctatctttt gctcaatctc tttttaacca gttttgtcat ccaattttca
    25801 gctcaatcga ttggccctat tttggctctt tatgtacgcg atttagggca gacagagaat
    25861 cttctttttg tctctggttt gattgtgtcc agtatgggct tttccagcat gatgagtgca
    25921 ggagtcatgg gcaagctagg tgacaaggtg ggcaatcatc gtctcttggt tgtcgcccag
    25981 ttttattcag tcatcatcta tctcctctgt gccaatgcct ctagccccct tcaactagga
    26041 ctctatcgtt tcctctttgg attgggaacc ggtgccttga ttcccggggt taatgcccta
    26101 ctcagcaaaa tgactcccaa agccggcatt tcgagggtct ttgccttcaa tcaggtattc
    26161 ttttatctgg gaggtgttgt tggtcccatg gcaggttctg cagtagcagg tcaatttggc
    26221 taccatgctg tcttttatgc gacgagcctt tgtgttgcct ttagttgtct ctttaacctg
    26281 attcaatttc gaacattatt aaaagtaaag gaaatctagt gcgagtaaaa attaatctca
    26341 aatgctcctc ttgtggcagt atcaattacc taaccagtaa aaattcaaaa acccatccag
    26401 acaagattga ggttttaaag tattgtccca aggaaagaaa agtaacccta catcttgaat
    26461 ctaagtagat tttatggtaa aataataggg attttaagga gtttgatatg tataacctat
    26521 tattaaccat tttattagta ttatctgttg tgattgtgat tgcaattttc atgcaaccaa
    26581 ccaaaaacca atccagcaat gtatttgatg ccagttcagg tgatttgttt gaacgtagta
    26641 aagctcgcgg ttttgaagct gtaatgcagc gtttgacagg gattttagtc tttttctggc
    26701 tagccattgc cttagcattg acggtattat caagtagata agaaaataat gggcaggact
    26761 aggtctttgc ctctttttat ttttaaagga tgtttgagaa ggttttacag taaaagaaaa
    26821 ttaaaaaatc tagaaagaaa atatgaaaga tagaataaaa gaatatttac aagacaaggg
    26881 aaaggtgact gttaatgatt tggctcaggc tttgggaaaa gacagttcca aggattttcg
    26941 tgagttgatt aaaaccttgt ccttaatgga aagaaagcac caaattcgtt ttgaagaaga
    27001 tggtagtctg acattagaaa ttaagaaaaa acatgagatt accctcaagg ggatttttca
    27061 tgcccataaa aatggctttg gctttgttag tctggaaggc gaggaggacg acctttttgt
    27121 agggaaaaat gatgtcaact atgctattga tggtgatacc gtcgaggtag tgattaagaa
    27181 agtcgctgac cgcaataagg gaacagcagc agaagccaaa attattgata tcctagaaca
    27241 cagtttgaca acagttgtcg ggcaaatcgt tctggatcag gaaaaaccta agtatgctgg
    27301 ctatattcgt tcaaaaaatc agaaaatcag tcaaccgatt tatgttaaga aaccagccct
    27361 aaaattagaa ggaacagaag ttctcaaagt ctttatcgat aaatacccaa gcaagaaaca
    27421 tgatttcttt gtcgcgagtg ttctcgatgt agtgggacac tcaacggatg tcggaattga
    27481 tgttcttgag gtcttggaat caatggacat tgtatccgag tttccagaag ctgttgttaa
    27541 ggaagcagaa agtgtgcctg atgctccgtc tcaaaaggat atggaaggtc gtctggatct
    27601 aagagatgaa attaccttta ccattgacgg tgcggatgcc aaggacttgg acgatgcagt
    27661 gcatatcaag gctctgaaaa atggcaatct ggagcttggg gttcacatcg cagatgtttc
    27721 ttattatgtg accgaggggt ctgcccttga caaggaagcc cttaaccgtg cgacttctgt
    27781 ttacgtgaca gaccgagtgg tgccaatgct tccagaacga ctatcaaatg gcatctgctc
    27841 tctcaatccc caagttgacc gcctgaccca gtctgctatt atggagattg ataaacatgg
    27901 tcgtgtggtc aactatacca ttacacaaac agttatcaag accagttttc gtatgaccta
    27961 tagcgatgtc aatgatatcc tagctggcga tgaagaaaag agaaaagaat atcataaaat
    28021 tgtatcaagt atcgaactca tggccaagct tcatgaaact ttagaaaaca tgcgtgtgaa
    28081 acgtggagct ctcaattttg ataccaatga agcgaagatt ttagtggata aacaaggtaa
    28141 gcctgttgat atcgttcttc ggcagcgtgg tattgccgag cggatgattg agtcttttat
    28201 gttgatggct aatgaaacag ttgccgaaca tttcagcaag ttggatttgc cttttatcta
    28261 tcgaattcac gaggagccta aggctgaaaa ggttcagaag tttattgatt atgcttcgag
    28321 ttttggcttg cgcatttatg gaactgccag tgagattagt caggaggcac ttcaagacat
    28381 catgcgtgct gttgagggag aaccttatgc agatgtattg tccatgatgc ttcttcgctc
    28441 tatgcagcag gctcgttatt cggagcacaa tcacggccac tatggactag ctgctgacta
    28501 ttatactcac tttaccagtc caattcgtcg ttatccagac cttcttgttc accgtatgat
    28561 tcgggattac ggccgttcta aggaaatagc agagcatttt gaacaagtga ttccagagat
    28621 tgcgacccag tcttccaacc gtgaacgtcg tgccatagaa gctgagcgtg aagtcgaagc
    28681 catgaaaaag gctgagtata tggaagaata cgtgggtgaa gagtatgatg cagttgtatc
    28741 aagtattgtc aaattcggtc tctttgtcga attgccaaac acagttgaag gcttgattca
    28801 catcactaat ctacctgaat tttatcattt caatgagcgt gatttgactc ttcgtggaga
    28861 aaaatcaggt atcactttcc gagtgggtca gcagatccgt atccgtgttg aaagagcgga
    28921 taaaatgact ggagagattg atttttcatt cgtacctagt gagtttgatg tgattgaaaa
    28981 aggcttgaaa cagtctagtc atagtggcag agggcgtggt tcaaatcgtc gttcggataa
    29041 gaaggaagac aagagaaaat caggacgctc aaatgataag cgtaagcatt cacaaaaaga
    29101 caagaagaaa aaaggaaaga aaccttttta caaggaagta gctaagaaag gagccaagca
    29161 tggcaaaggg cgagggaaag gtcgtcgcac aaaataaaaa ggcacgccac gactatacaa
    29221 tcgtagatac gctagaggca gggatggtcc tgactggaac tgaaatcaag agtgtacgag
    29281 ctgctcgaat taatctcaag gatggctttg ctcaagtgaa aaatggagaa gtttggctga
    29341 gcaatgttca tatcgcgcct tacgaagagg gcaatatctg gaaccaggaa ccagaacgtc
    29401 gtcgtaaact cctgctccat aaaaagcaaa ttcaaaaatt ggaacaagag accaaaggga
    29461 caggaatgac cttagttccc cttaaggtct atataaaaga tggctacgct aagcttcttt
    29521 taggacttgc caaagggaag catgactatg acaaacggga gtctatcaaa cgtcgtgagc
    29581 aaaatcgaga tatcgcgcgt gtgatgaaag ctgttaatca gcgataaaaa gaggaattga
    29641 aaatggaaaa attagttgcc tataaacgca tgcctttgtg gaataaacaa acaatgcctg
    29701 aagatgttca gcaaaagcac aatacaaaag ttgggacttg ggggaaaatt actgtcttga
    29761 agggagctct caagtttatt gaattgacag aagaagggga agttctagct gaacacctct
    29821 ttgaagcagg ggcagacaat ccaatggccc aacctcaagc ctggcaccga gtggaagctg
    29881 ccacagatga tgtggaatgg tacttggaat tttattgtaa acctgaggat tattttgcta
    29941 aaaaatacaa taccaatcct gttcattcag aggtcctaga ggccatgcag acagtgaaac
    30001 aagggaaagc tttggatttg ggttgtggtc aggggcgtaa ttctcttttt ctagcccagc
    30061 aagattttga tgtgacggct gtagatcaaa atggactagc tcttgaaatc ttgcaaagca
    30121 ttgtggagca ggaagatttg gacatgcctg ttggccttta cgatatcaat tcagctagca
    30181 ttgaacaaga atatgatttt atcgtttcaa cagttgttct catgtttcta caagcggacc
    30241 gcattccagc tattattcaa aatatgcagg agaaaaccag tgttggtggt tacaacctta
    30301 tcgtttgtgc catggacacg gaggattatc cttgctcggt taatttccca ttcaccttta
    30361 aagaaggaga actggcagac tattacaagg attgggaatt ggttaagtac aatgaaaatc
    30421 caggccattt gcaccgtcgc gatgagaatg gcaatcgtat tcaactacgc tttgcgacct
    30481 tactagctaa gaaaatcaag taaacacaca tgaagattag gaattttcct gatctttttt
    30541 cttttttacg aatgatatag aaaaggaggg aattcatgtt tgttgcgaga gatgctaggg
    30601 gagaattggt aaatgtgtta gaggataaac ttgagaagca agcatacacc tgcccagctt
    30661 gtggaggcca gctccatttg cgtcaaggac caagtgtacg gacgcatttt gcccataaat
    30721 ccttaaaaga ctgtgatttt ttctttgaaa atgaaagtcc agaacacctg gccaataagg
    30781 aatccctcta tcactggttg aaaaaagaga caaaggttca attagagtac ccgctttcag
    30841 aacttaaaca gattgcggat gtatttgtaa atggcaatct agctctagaa gttcagtgta
    30901 gtcccttgcc tcagaaagtc cttaaagagc gaagtgaggg atatcgtagt cagggttacc
    30961 aagtactgtg gttgctgggt caaaaactgt ggctcaagga gcgtttgact cgtctacagc
    31021 aaggttttct ttatttcagt caaaacatgg gcttttatgt ttgggaatta gacaaggaaa
    31081 aacaagtttt aagactcaaa tacctgattt accaggatct ccgcggtaaa ctccattatc
    31141 aaatcaagga attttcctat ggtcaaggta
//
LOCUS       DAVBBO010000021        31002 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ST1
            SAMEA2066453-rid20184263.denovo.021, whole genome shotgun sequence.
ACCESSION   DAVBBO010000021 DAVBBO010000000
VERSION     DAVBBO010000021.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2066453
            Sequence Read Archive: ERR351777
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 31002)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 31002)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980402.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980402.1
            Genome Coverage       :: 176x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:17:33
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,141
            CDSs (total)                      :: 2,104
            Genes (coding)                    :: 1,953
            CDSs (with protein)               :: 1,953
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 16S)
            partial rRNAs                     :: 1 (23S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 151
            CDSs (without protein)            :: 151
            Pseudo Genes (ambiguous residues) :: 0 of 151
            Pseudo Genes (frameshifted)       :: 73 of 151
            Pseudo Genes (incomplete)         :: 76 of 151
            Pseudo Genes (internal stop)      :: 40 of 151
            Pseudo Genes (multiple problems)  :: 32 of 151
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..31002
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2066453-rid20184263.denovo.021"
                     /strain="ST1"
                     /db_xref="taxon:1313"
     gene            complement(298..516)
                     /locus_tag="VQU30_000955"
     CDS             complement(298..516)
                     /locus_tag="VQU30_000955"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001207345.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HET2447084.1"
                     /translation="MVLNYKPLWIQLAKKGLKKTDVIAMAGLTTNVMAQMGKDKPITF
                     KNLERICKALSCTPNDIISFEDNFSDEE"
     gene            complement(762..1040)
                     /locus_tag="VQU30_000956"
     CDS             complement(762..1040)
                     /locus_tag="VQU30_000956"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000710796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2447085.1"
                     /translation="MKKDKEVYDKVCEYLSPHLNKDMEMLELACWFRVIIVIEANSYV
                     NIRSSRLLPKFKTQKINSWCAAYSIHFNNGYCKQHTNEFKDSLKSLIL"
     gene            complement(1254..2885)
                     /gene="rlmD"
                     /locus_tag="VQU30_000957"
     CDS             complement(1254..2885)
                     /gene="rlmD"
                     /locus_tag="VQU30_000957"
                     /EC_number="2.1.1.190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000914584.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (uracil(1939)-C(5))-methyltransferase
                     RlmD"
                     /protein_id="HET2447086.1"
                     /translation="MLKKNDIVEVEIVDLTHEGAGVAKVDGLVFFVENALPSEKILMR
                     VLKVNKKIGFGKVEKYLVQSLHRNQDLDLAYLRSGIADLGHLSYPEQLKFKTKQVKDS
                     LYKIAGIADVEVAETLGMEHPVKYRNKAQVPVRRVNGVLETGFFRKNSHNLMPLEDFF
                     IQDPVIDQVVVALRDLLRRFDLKPYDEKEQSGLIRNLVVRRGHYSGQIMVVLVTTRPK
                     VFRVDQLIEQVIKQFPEIVSVMQNINDQNTNAIFGKEWCTLYGQDYITDQMLGNDFQI
                     AGPAFYQVNTEMAEKLYQTAIDFAELKKDDVVIDAYSGIGTIGLSVAKHVKEVYGVEL
                     IPEAVENSQKNASLNKITNAHYVCDTAENAMKKWLKEGIQPTVILVDPPRKGLTESFI
                     KASAQTGADRIAYISCNVATMARDIKLYQELGYELKKVQPVDLFPQTHHVETVALLSK
                     LDVDKHISVEIELDEMDLTSAESKATYAQIKEYVWNKFELKVSTLYIAQIKKKCGIEL
                     REHYNKSKKDKQIIPQCTPEKEEAIMDALRHFKMI"
     gene            complement(2959..3933)
                     /locus_tag="VQU30_000958"
     CDS             complement(2959..3933)
                     /locus_tag="VQU30_000958"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001227757.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1002 domain-containing protein"
                     /protein_id="HET2447087.1"
                     /translation="MRKKLFLTSAAVLWAVTAMNSVHAATDVQKVIDETYVQPEYVLG
                     SSLSEDQKNQTLKKLGYNASTDTKELKTMTPDVYSKIMNVANDSSLQLYSSAKIQKLG
                     DKSPLEVKIETPENITKVTQDMYRNAAVTLGMEHAKITVAAPIPVTGESALAGIYYSL
                     EANGAKVPQANKDLAQEELKALSDINAENKDKSGYDANKLNVALADIKSGLAKAKESK
                     GNLTEEDVRKIVEDTLKNYKLDQVITGNQINIIINFALNLSKSDILSNADFTKTLNDL
                     KQSIVSQAGDSFKNINLNFDADKALEDGGNFLSSLWQALVNFFKSFGS"
     gene            complement(4007..4621)
                     /gene="pmp23"
                     /locus_tag="VQU30_000959"
     CDS             complement(4007..4621)
                     /gene="pmp23"
                     /locus_tag="VQU30_000959"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000476388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall hydrolase Pmp23"
                     /protein_id="HET2447088.1"
                     /translation="MFKRIRRVLVLAVFLFAGYKAYRVHQDVKQVMTYQPMVREILSE
                     KDTPANEELVLAMIYTETKGKEGDVMQSSESASGSTNTINDNASSIRQGIQTLTGNLY
                     LAQKKGVDIWTAVQAYNFGPAYIDFIAQNGKENTLALAKQYSRETVAPLLGNTTGKTY
                     SYIHPISIFHGAELYVNGGNYYYSRQVRLNLYIIKCFTLFSTSG"
     gene            complement(4621..5595)
                     /locus_tag="VQU30_000960"
     CDS             complement(4621..5595)
                     /locus_tag="VQU30_000960"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006153495.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoid-associated protein"
                     /protein_id="HET2447089.1"
                     /translation="MDIYIKKAIIHQFSPDDTELFLADKFLNITPKIEEYLRKKIEHV
                     YSDEAKTGIFEEENPFFNHITDDLLETSVTLANLWKEEFSISENLKTNDLIFVQFSKE
                     GVEHFAFLRIALRETLTHLGGEVDNPIKLTQNNLPGFGTGADEALVVNLQSRKYHLIE
                     KRIKYNGTFLNYFSDNLLAVAPKISPKKSIKELEKTAQRIAESFNTDDFQFQSKVKSA
                     IFNNLEESNELSPEKLANDLFDNNLTARLSFIDQVKEAVPEPVQFDEIDASRQLKKFE
                     NQKLSLSNGIELIVPNNVYQDAESVEFIQKENGTYSILIKNIEDIQSK"
     gene            complement(5603..6859)
                     /locus_tag="VQU30_000961"
     CDS             complement(5603..6859)
                     /locus_tag="VQU30_000961"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863152.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine hydroxymethyltransferase"
                     /protein_id="HET2447090.1"
                     /translation="MIFDKDDFKAYDADLWNAIAKEEERQQNNIELIASENVVSKAVM
                     AAQGSILTNKYAEGYPGRRYYGGTDVVDVVETLAIERAKEIFGAKFANVQPHSGSQAN
                     CAAYMSLIEPGDTVMGMDLASGGHLTHGAPVSFSGQTYNFVSYSVDPETELLDFDAIL
                     KQAQEVKPKLIVAGASAYSQIIDFSKFREIADAVGAKLMVDMAHIAGLVAAGLHPSPV
                     PYAHITTTTTHKTLRGPRGGLILTNDEELAKKINSAIFPGIQGGPLEHVVAAKAVSFK
                     EVLDPAFKEYAANVIKNSKAMADVFLQDPDFRIISGGTENHLFLVDVTKVVENGKVAQ
                     NLLDEVNITLNKNSIPYETLSPFKTSGIRIGAAAITARGFGEEESRKVAELIIKTLKN
                     SENEAVLEEVRSAVKELTDAFPLYEE"
     gene            complement(6921..7352)
                     /locus_tag="VQU30_000962"
     CDS             complement(6921..7352)
                     /locus_tag="VQU30_000962"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000942930.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HET2447091.1"
                     /translation="MLRDLQETDVKAICDINQEALGYTFSPEETASQLARLSQDSHHF
                     LLGYEDAANHVLLGYVHAEVYESLYSKAGFNILALAVSPQAQGQGIGKSLLQGLEQEA
                     KRCGYGFIRLNSANHRLGAHAFYEKVGYTCDKMQKRFIRIF"
     gene            complement(7354..7956)
                     /locus_tag="VQU30_000963"
     CDS             complement(7354..7956)
                     /locus_tag="VQU30_000963"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000969297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonylcarbamoyl-AMP synthase"
                     /protein_id="HET2447092.1"
                     /translation="MMDRIRQELENGGAVVLPTETVYGLFAKALDEKAVDHVYQLKRR
                     PRDKALNLNIASFEDILHFSKNQPTYLQKLVETFLPGPLTIILEANDRVPYWVNSDLA
                     TIGFRMPSHPITLDLIRETGPLIGPSANISGQASGVTFEQILKDFDQEVLGLEDDAFL
                     TGQDSTIVDLSGDKVKILRQGAIKREDILARLPEISFEEA"
     gene            complement(7940..8779)
                     /gene="prmC"
                     /locus_tag="VQU30_000964"
     CDS             complement(7940..8779)
                     /gene="prmC"
                     /locus_tag="VQU30_000964"
                     /EC_number="2.1.1.297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000761890.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor N(5)-glutamine
                     methyltransferase"
                     /protein_id="HET2447093.1"
                     /translation="MKLAQLFSNFEEELIRQGEEAESLSFVYRSLKNLSFTDFIFALQ
                     QEVTTEEEKQFVEDIYQQLAAHKPAQYIIGQADFYGMHLKVDERVLIPRPETEELVEL
                     ILTENLETNLSVLDIGTGSGAIALALAKNRPDWSVTAADVSQEALELASENASDQNLN
                     IFFKKSDCFAEISEKYDIIVSNPPYISREDESEVGLNVLHSEPHLALFADEDGLAIYC
                     RIAEDAKDYLKDGGKIYLEIGYKQGQSVPELFRKHLPEKKVRTLKDQFGQNRMVVVDD
                     GQD"
     gene            complement(8779..9858)
                     /gene="prfA"
                     /locus_tag="VQU30_000965"
     CDS             complement(8779..9858)
                     /gene="prfA"
                     /locus_tag="VQU30_000965"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002262255.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 1"
                     /protein_id="HET2447094.1"
                     /translation="MNIYDQLQAVEDRYEELGELLSDPDVVSDTKRFMELSKEEASNR
                     DTVIAYREYKQVLQNIVDAEEMIKESGGDADLEEMAKQELKDAKAEKEEYEEKLKILL
                     LPKDPNDDKNIILEIRGAAGGDEAALFAGDLLTMYQKYAEAQGWRFEVMEASMNGVGG
                     FKEVVAMVSGQSVYSKLKYESGAHRVQRVPVTESQGRVHTSTATVLVMPEVEEVEYDI
                     DPKDLRVDIYHASGAGGQNVNKVATAVRIVHLPTNIKVEMQEERTQQKNREKAMKIIR
                     ARVADHFAQIAQDEQDAERKSTIGTGDRSERIRTYNFPQNRVTDHRIGLTLQKLDTIL
                     SGKLDEVVDALVLYDQTQKLEELNK"
     gene            complement(9855..10445)
                     /locus_tag="VQU30_000966"
     CDS             complement(9855..10445)
                     /locus_tag="VQU30_000966"
                     /EC_number="2.7.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000068157.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thymidine kinase"
                     /protein_id="HET2447095.1"
                     /translation="MAQLYYRYGTMNSGKTIEILKVAYNYEEQGKGVVIMTSALDTRD
                     GVGYVSSRIGMKRPALAIEETTDIFGYIRGLPEKPYCVLVDEAQFLKRHHVYDLARVV
                     DELDIPVMAFGLKNDFRNELFEGSKYLLLLADKIDEIKTICQYCKKKATMVLRTQDGL
                     PVYDGEQIQIGGNETYISVCRKHYFAPEINKENEEK"
     gene            10568..10750
                     /locus_tag="VQU30_000967"
     CDS             10568..10750
                     /locus_tag="VQU30_000967"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005589823.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-oxalocrotonate tautomerase"
                     /protein_id="HET2447096.1"
                     /translation="MPFVRIDLFEGRTLEQKKALAKEVTEAVVRNTGAPQSAVHVIIN
                     DMPEGTYFPQGEMRTK"
     gene            10887..12260
                     /gene="mnmE"
                     /locus_tag="VQU30_000968"
     CDS             10887..12260
                     /gene="mnmE"
                     /locus_tag="VQU30_000968"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002906470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA uridine-5-carboxymethylaminomethyl(34)
                     synthesis GTPase MnmE"
                     /protein_id="HET2447097.1"
                     /translation="MITREFDTIAAISTPLGEGAIGIVRLSGTDSFAIAQKIFKGKDL
                     NKVASHTLNYGHIIDPLTGKVMDEVMVGAMKSPKTFTREDIIEINTHGGIAVTNEILQ
                     LAIREGARLAEPGEFTKRAFLNGRVDLTQAEAVMDIIRAKTDKAMNIAVKQLDGSLSD
                     LINNIRQEILNTLAQVEVNIDYPEYDDVEEATTAVVREKTMEFEQLLTKLLRTARRGK
                     ILREGISTAIIGRPNVGKSSLLNNLLREDKAIVTDIAGTTRDVIEEYVNINGVPLKLI
                     DTAGIRETDDIVEQIGVERSKKALKEANLVLLVLNASEPLTAQDRQLLEISQDTNRII
                     LLNKTDLPETIETSKLPEDVIRISVLKNQNIDKIEERINNLFFENAGLIEQDATYLSN
                     ARHISLIEKAVESLQAVNQGLELGMPVDLLQVDLTRTWEILGEITGDAAPDELITQLF
                     SQFCLGK"
     gene            complement(12307..13242)
                     /gene="dapA"
                     /locus_tag="VQU30_000969"
     CDS             complement(12307..13242)
                     /gene="dapA"
                     /locus_tag="VQU30_000969"
                     /EC_number="4.3.3.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002935444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxy-tetrahydrodipicolinate synthase"
                     /protein_id="HET2447098.1"
                     /translation="MSYQDLKECKIITAFITPFHEDGSINFDAIPALIEHLLAHHTDG
                     ILLAGTTAESPTLTHDEELELFAAVQKVVNGRVPLIAGVGTNDTRDSIEFVKEVAEFG
                     GFAAGLAIVPYYNKPSQEGMYQHFKTIADASDLPIIIYNIPGRVVVELTPETMLRLAD
                     HPNIIGVKECTSLANMAYLIEHKPEEFLIYTGEDGDAFHAMNLGADGVISVASHTNGD
                     EMHEMFTAIAESDMKKAAAIQRKFIPKVNALFSYPSPAPVKAILNYMGFEAGPTRLPL
                     VPAPEEDAKRIIKVVVDGDYEATKATVTGVLRPDY"
     gene            complement(13298..14374)
                     /locus_tag="VQU30_000970"
     CDS             complement(13298..14374)
                     /locus_tag="VQU30_000970"
                     /EC_number="1.2.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000542485.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate-semialdehyde dehydrogenase"
                     /protein_id="HET2447099.1"
                     /translation="MGYTVAVVGATGAVGAQMIKMLEESTLPIDKIRYLASARSAGKS
                     LKFKDQDITIEETTETAFEGVDIALFSAGSSTSAKYAPYAVKAGVVVVDNTSYFRQNP
                     DVPLVVPEVNAHALDAHNGIIACPNCSTIQMMVALEPVRQKWGLDRIIVSTYQAVSGA
                     GMGAILETQRELREVLNDGVKPCDLHAEILPSGGDKKHYPIAFNALPQIDVFTDNDYT
                     YEEMKMTKETKKIMEDDSIAVSATCVRIPVLSAHSESVYIETKEVAPIEEVKAAIAAF
                     PGAVLEDDVAHQIYPQAINAVGSRDTFVGRIRKDLDAEKGIHMWVVSDNLLKGAAWNS
                     VQIAETLHERGLVRPTAELKFELK"
     gene            complement(14716..14788)
                     /locus_tag="VQU30_000971"
     tRNA            complement(14716..14788)
                     /locus_tag="VQU30_000971"
                     /product="tRNA-Thr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(14753..14755),aa:Thr,seq:ggt)
     gene            complement(14888..15397)
                     /locus_tag="VQU30_000972"
     CDS             complement(14888..15397)
                     /locus_tag="VQU30_000972"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004262434.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="QueT transporter family protein"
                     /protein_id="HET2447100.1"
                     /translation="MKKLTIRDIADIAIVAAIYVVLTVTPPLNAISYGAYQFRISEMM
                     NFMAFYNPKYIIGVTIGCMIANFFSFGLLDVFVGGGSTLVFLSLGVWLFAKYSKDYLF
                     NGLIRKDHFFFSILFSISMFTIAAELNIVAELPFFLTWFTTGIGEFASLIIGAIIIGK
                     IGRRIDLSK"
     regulatory      complement(15395..15491)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF01054"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="PreQ1 riboswitch class II; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="preQ1"
                     /db_xref="RFAM:RF01054"
     gene            15520..15951
                     /locus_tag="VQU30_000973"
     CDS             15520..15951
                     /locus_tag="VQU30_000973"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000743000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GtrA family protein"
                     /protein_id="HET2447101.1"
                     /translation="MKIPIQKFFNNEILAYLFFGLATTLVSILSRLVIYQLSHQELLA
                     TALANIIGILFAFITNDTIVFKQKKKNRLIRLVKFSLARLSTFLLDLFLTFLFVTQFP
                     HIIGQFVTENIDKINAIETIIAQIFIIIINYILSKAYIFRK"
     gene            16033..16410
                     /gene="mscL"
                     /locus_tag="VQU30_000974"
     CDS             16033..16410
                     /gene="mscL"
                     /locus_tag="VQU30_000974"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001855364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="large conductance mechanosensitive channel
                     protein MscL"
                     /protein_id="HET2447102.1"
                     /translation="MLKNLKSFLLRGNVIDLAVGVVIASAFGAIVTSLVNDIITPLIL
                     NPALKAAKVERIAQLSWHGVGYGNFLSAIINFIFVGTALFFIIKGIEKAQKLTGIKKE
                     KTAEKKPTELEVLQEIKALLEKK"
     gene            complement(16452..17546)
                     /gene="hemH"
                     /locus_tag="VQU30_000975"
     CDS             complement(16452..17546)
                     /gene="hemH"
                     /locus_tag="VQU30_000975"
                     /EC_number="4.98.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004254302.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferrochelatase"
                     /protein_id="HET2447103.1"
                     /translation="MKKAILMMTFGSPEEISFEGVAEFFTNIRRGVRPQDHEIQTLYD
                     NYIRIGGTPLQRITREEVNLVKERLGEEYGIYFANKFSRPFIPDVIKQMETDGVEECI
                     CLILEPHYSFYSVMGYEKFLESKQIQFLVIKDWYQEEVLLNYWADEIAKILKEEVKQD
                     SFKVIFSAHSVPIFALDFGDPYIDQIFENSKLVAEKLGLSSEQYTNTWQSESDIGIPW
                     IKPDVLEYLREQTEHPDHYIFVPISFISEHIEVLFDNDVECYDLCQEFGVNYHRPPMP
                     NTDSRLIDALVNTVRVNENQEFKEFLPEEETFDELVPSDETKNILAESEDLQMPEFVK
                     KLIEKKGRENVKMPYLIKKMLEKAGKLPKE"
     gene            complement(17624..18456)
                     /gene="srtG2"
                     /locus_tag="VQU30_000976"
                     /pseudo
     CDS             complement(17624..18456)
                     /gene="srtG2"
                     /locus_tag="VQU30_000976"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000218039.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="PI-2 pilus system class B sortase SrtG2"
     gene            complement(18534..19532)
                     /gene="srtG1"
                     /locus_tag="VQU30_000977"
     CDS             complement(18534..19532)
                     /gene="srtG1"
                     /locus_tag="VQU30_000977"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000851047.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PI-2 pilus system class B sortase SrtG1"
                     /protein_id="HET2447104.1"
                     /translation="MKTKREKPKKSLSRRLVLAVDGVINHLLLIFAALIFLFGFYALW
                     DSNQVYSLASSSEYEAYRPVTTQQDELASFSGFSKLQELNPEVLGWINVYGTNIDYPL
                     VQAKDNEKYLNKDSKGEFAATGAIFLDARNNPKFEDFNTIIYGHHVENGVMFGDVAKF
                     ADQEFFDQHRYGSIYYNGVEKGLEIFEMLEVDAYDFNIYDPGIQGEDRQQAYLDHLLS
                     VAMHKRDISLSPSDRIILLSTCFLDVTNGRHIVVAKITDTVPKNTFHTKKSKPFPYSV
                     FDDSSLGRFLSSIPLWIWYLILFVLFLLLIFLLLVLYLILRRRRESKKNARSRPFY"
     gene            complement(19550..20746)
                     /gene="pitB"
                     /locus_tag="VQU30_000978"
     CDS             complement(19550..20746)
                     /gene="pitB"
                     /locus_tag="VQU30_000978"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000750612.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PI-2 pilus major pilin PitB"
                     /protein_id="HET2447105.1"
                     /translation="MKKTFFKKLFTASIAAITALSVFRGVPTFADDNSAITKANGENN
                     AVVKINKTLNIAEGITTPTATFTFKFTEKTGQSSNGAPYQTGVAIPDRNVEYNKNDHP
                     TADKIQKATEDIFSGVAYGHAGEYVYDVAEAKTGWQAITKNGKTIDAMRYDKRTYEMH
                     VIVKNKVNGGVYISSVYFKENNKSNAPKVEPSEQGVYNLFDNTYTKDASKEPNPDDPS
                     QVDPNAKALTITKKVDGASGDKTRDFQFHIKIQLPSTNKTAETPVTNIIVKHGSKSEV
                     LAVVTPADTVEYNFTLKDGETFTVEQLPAGSKYTVTETGVAGYTDSSIYTTNGAEQTS
                     QGQKNVDFTLTDILIGEKKNDNKVTNKIDDVTPTGLLIDNLPFILMIGLGLAGFVVLS
                     KKRREA"
     gene            complement(20791..21342)
                     /gene="sipA"
                     /locus_tag="VQU30_000979"
     CDS             complement(20791..21342)
                     /gene="sipA"
                     /locus_tag="VQU30_000979"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000924780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PI-2 pilus system signal peptidase SipA"
                     /protein_id="HET2447106.1"
                     /translation="MLLKKKHKKPVTQVNRDKSPPSVWGDILYLVSKLLMVGFVLAIL
                     YFFVFGLLRYNDDGMKPALKDGDLVVYYRLDKRYSIGDLLVYSYKGKERVARVIATEG
                     STIDINENGLIINGSPQQEQDIYKETLLYKEGATFPMKVPAGQLFVLGDNRTTAVDSR
                     AFGTIPIQDTQGKVVTVIRRRGF"
     gene            complement(21342..23297)
                     /locus_tag="VQU30_000980"
     CDS             complement(21342..23297)
                     /locus_tag="VQU30_000980"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="VWA domain-containing protein"
                     /protein_id="HET2447107.1"
                     /translation="MDAGIGTGTNINAGLTEAQRLLQSARAGAKKVVILLSDGEANMY
                     YESNSGRTIYNYYSNPNVGRMIDTPYWFTSGLERGMLNISSLIAPKIDGFYSIKFRYY
                     IGSNDSITSLKGYISGYNSGIPNEIFSANNENDLQQKFKEITDKILPLGVHHVTISDV
                     LSKYVQLLPGDASHLRVVKIKDGNEQELNDNQVTIETKKNEQGLVEVTAKFNPSYTLE
                     DDAKYVLKFTVTSSQEAFDAIAGDKTLTSDDAEEADATKLYSNKGAKVAYSYGIGTSR
                     TKIKDYSEKPTFKPSDPLTVPVEIEWKGVDGKSNPSANRPPSVELNLNQKKDGSIKDS
                     YRKVTSPVQTNSFTENTSFAKVAKGYDYELKAPDAPGYTVEVQKTGTKEKPSFKVIYR
                     QLPSLTVKKILEGEQSPNKSFTINVTFSDKDGKPINGKFGNTTVTNGKAQISLKNSQE
                     TALSYLPRDTHYKVEEVENSRTGYHVTYEKQEGTLSEDVQTIVTNHRLPTLSVTKKVT
                     GAFANLLQSFKITINVKDAQNKPLNGSYSAIVNNQKTTLQFTNGKATVDLKKDKTIKI
                     LDLPLNARYSIEEEASSSRGYQVSYDKKEGTLDANKSATVTNNKNSVPETGIDFLSST
                     LVLGVVLPLGGIFFIILLGHLVVNRRK"
     gene            complement(23427..23930)
                     /locus_tag="VQU30_000981"
     CDS             complement(23427..23930)
                     /locus_tag="VQU30_000981"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001102795.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adhesin"
                     /protein_id="HET2447108.1"
                     /translation="MNVQYDFKKIQYFTSSLVIFLAILFLCAPINSLRADSITEPQTT
                     LHKTITPISGQKDQYELSLDITSKLGTETQSEPLDVVLVADLSGSMEERDVWSYSSRR
                     YISRIEALKHTLKGVNGRQGLIDTILSNSQNRLSIVGFAGKIDNQYNDRYYNEYYLSY
                     QYGTWPN"
     gene            24289..25512
                     /gene="pepT"
                     /locus_tag="VQU30_000982"
     CDS             24289..25512
                     /gene="pepT"
                     /locus_tag="VQU30_000982"
                     /EC_number="3.4.11.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000222045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase T"
                     /protein_id="HET2447109.1"
                     /translation="MTYPNLLDRFLTYVKVNTRSDEHSTTTPSTQSQVDFATNVLIPE
                     MKRVGLQNVYYLPNGFAIGTLPANDPSLTRKIGFISHMDTADFNAEGVNPQVIENYDG
                     GVIELGNSGFKLDPADFKSLEKYPRQTLITTDGTTLLGADDKSGIAEIMTAIEYLTAH
                     PEIKHCEIRVGFGPDEEIGVGANKFDAEDFDVDFAYTVDGGPLGELQYETFSAAGAEL
                     HFQGRNVHPGTAKGQMVNALQLAIDFHNQLPENDRPELTEGYQGFYHLMDVTGSVEEV
                     RASYIIRDFEKDAFEARKASMQSIADKMNEELGSDRVTLNLTDQYYNMKEVIEKDMTP
                     ITIAKAVMEDLGITPIIEPIRGGTDGSKISFMGIPTPNIFAGGENMHGRFEYVSLQTM
                     ERAVDTIIGIVAYKG"
     gene            complement(25548..26177)
                     /locus_tag="VQU30_000983"
     CDS             complement(25548..26177)
                     /locus_tag="VQU30_000983"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000030436.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2447110.1"
                     /translation="MNKANQLLEQIHEEGIRQSLAEEVENLKAATNKADADLDEVNSQ
                     VKDVLTRIASALQQEKENAEQDSQTLVLYQKLYDILMSLHSYLESNNGSDADFDKVDA
                     LLDQLSANSKDKTALLESTKAILVLNHQIQSKVSASEETSPARNAEANSDNTSAENQP
                     NATAESNIETASDENKPSNTRDSKPAESTSENETTESSTTTGNQEKPVE"
     gene            26142..26363
                     /locus_tag="VQU30_000984"
     CDS             26142..26363
                     /locus_tag="VQU30_000984"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844654.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2447111.1"
                     /translation="MDLFQELICLVQKTFYFFLAICRRLLVAIYHVLLKQESYNPRLQ
                     GLTEIRNPDKTMFVQDAIRFAQQHGFNML"
     gene            complement(26634..26982)
                     /locus_tag="VQU30_000985"
                     /pseudo
     CDS             complement(26634..26982)
                     /locus_tag="VQU30_000985"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000669441.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus and C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="pneumococcal-type histidine triad protein"
     gene            complement(27087..27647)
                     /locus_tag="VQU30_000986"
                     /pseudo
     CDS             complement(27087..27647)
                     /locus_tag="VQU30_000986"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000669441.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="pneumococcal-type histidine triad protein"
     gene            complement(27873..30992)
                     /gene="phtE"
                     /locus_tag="VQU30_000987"
     CDS             complement(27873..30992)
                     /gene="phtE"
                     /locus_tag="VQU30_000987"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000672589.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pneumococcal histidine triad protein PhtE"
                     /protein_id="HET2447112.1"
                     /translation="MKFSKKYIAAGSAVIVSLSLCAYALNQHRSQENKDNNRVSYVDG
                     SQSSQKSENLTPDQISQKEGIQAEQIVIKITDQGYVTSHGDHYHYYNGKVPYDALFSE
                     ELLMKDPNYQLKDADIVNEVKGGYIIKVDGKYYVYLKDAAHADNVRTKDEINRQKQEH
                     VKDNEKVNSNVAVARSQGRYTTNDGYVFNPADIIEDTGNAYIVPHGGHYHYIPKSDLS
                     ASELAAAKAHLAGKNMQPSQLSYSSTASDNNTQSVAKGSTSKPANKSENLQSLLKELY
                     DSPSAQRYSESDGLVFDPAKIISRTPNGVAIPHGDHYHFIPYSKLSALEEKIARMVPI
                     SGTGSTVSTNAKPNEVVSSLGSLSSNPSSLTTSKELSSASDGYIFNPKDIVEETATAY
                     IVRHGDHFHYIPKSNQIGQPTLPNNSLATPSPSLPINPGTSHEKHEEDGYGFDANRII
                     AEDESGFVMSHGDHNHYFFKKDLTEEQIKAAQKHLEEVKTSHNGLDSLSSHEQDYPSN
                     AKEMKDLDKKIEEKIAGIMKQYGVKRESIVVNKEKNAIIYPHGDHHHADPIDEHKPVG
                     IGHSHSNYELFKPEEGVAKKEGNKVYTGEELTNVVNLLKNSTFNNQNFTLANGQKRVS
                     FSFPPELEKKLGINMLVKLITPDGKVLEKVSGKVFGEGVGNIANFELDQPYLPGQTFK
                     YTIASKDYPEVSYDGTFTVPTSLAYKMASQTIFYPFHAGDTYLRVNPQFAVPKGTDAL
                     VRVFDEFHGNAYLENNYKVGEIKLPIPKLNQGTTRTAGNKIPVTFMANAYLDNQSTYI
                     VEVPILEKENQTDKPSILPQFKRNKAQENSKLDEKVEEPKTSEKVEKEKLSETGNSTS
                     NSTLEEVPTVDPVQEKVAKFAESYGMKLENVLFNMDGTIELYLPSGEVIKKNMADFTG
                     EAPQGNGENKPSENGKVSTGTVENQPTENKPADSLPEAPNEKPVKPENSTDNGMLNPE
                     GNVGSDPMLDPALEEAPAVDPVQEKLEKFTASYGLGLDSVIFNMDGTIELRLPSGEVI
                     KKNLSDLIA"
BASE COUNT         8835 a         6360 c         5686 g        10121 t
ORIGIN      
        1 aaaaggatct agtttttatt tttagttaaa ttatgtctat atttttcatt aactcatcaa
       61 taaaaatttg tttgctaata tctctttctt ctgattttgt ttcaaggatt attgctacat
      121 cattcatatt tttaggtaaa taccaaccat ctggcttatc tgaatatccc ttgaagccta
      181 attgattaaa agtagttatt tgaccagtac cttgattgat gttttcttca acttcattaa
      241 agcctatact tctcttgcat aatccctaac ttgatcttct gtccttaaag tcattttcta
      301 ttcctcgtca ctaaaattat cttcaaaact aataatatca ttaggagtgc aagataaagc
      361 cttacatatt ctttctaaat tcttaaatgt aattggttta tcctttccca tttgtgccat
      421 aacatttgtt gtaagtcctg ccatagctat tacatctgtt ttctttagtc ctttttttgc
      481 taactgtatc cataatggtt tatagttaag taccataata tccctctttt tttcttcatt
      541 aaatttattt aattatagca taaatattga tttcattcaa tcttacattg atttagtgat
      601 ttgttttaga gaatttgttg tgttattccg tccttatttt gccataaatt gttttaagtg
      661 ggacctctta tccttaccat ttttacctcc taattttgag tataaaaaag acgatagagt
      721 ttttaatttc tatcgtctga gatttacata ttaaattttc atcacaaaat aagactcttt
      781 aaagaatctt taaattcatt ggtatgctgc ttacaatatc cattattaaa atggatacta
      841 taagcagcac accaactatt tattttttga gttttaaact ttggtagaag tcttgaactc
      901 cttatattta cataactatt tgcctctata actattatga cacgaaacca acaagcaagt
      961 tcaagcatct ccatatcttt attcaaatga ggactaagat attcacaaac tttatcataa
     1021 acctctttat cttttttcat aaaaggggca tacaacttag caaatttatc ctaaaatttt
     1081 ttgttgcctt tatcaatcat ttcaacgctc ctttaaatat aaaaataatc ctatcaatct
     1141 ttatattgag cctattttct aattgatacc ttgcaagaaa ggaataatag ctgttcctat
     1201 accaagtagg aatgtaataa atgcagaaag tcatatactg tcattctttt ctattaaatc
     1261 attttgaagt gtctcaaagc atccatgatg gcttcttctt tttcaggtgt acactgtgga
     1321 ataatttgtt tatccttttt agacttgttg taatgttctc gtaattctat tccacatttc
     1381 ttttttatct gtgcaatata taatgtcgaa acttttaatt caaatttatt ccaaacatat
     1441 tctttgattt gagcatatgt tgctttgctc tccgcacttg tcaaatccat ctcatccagc
     1501 tcaatttcaa cacttatgtg cttatcgaca tcgagtttgg acaaaagtgc taccgtctcg
     1561 acgtgatgcg tttgaggaaa tagatccacc ggctggactt tcttcaattc atatcccaat
     1621 tcttggtaga gtttgatatc acgcgccatg gttgcgacat tgcaggagat ataggcgatg
     1681 cgatcggctc ctgtttgggc gcttgctttg ataaagcttt ctgtcaagcc cttgcgtgga
     1741 ggatcaacca agataacggt tggttgaata ccttccttga gccatttctt catggcattt
     1801 tcagccgtgt cacagacata gtgggcatta gtaatcttgt tcaaagaagc attcttctgg
     1861 ctattctcaa ccgcttctgg aatcagttca acaccgtaga cttctttgac atgcttggcg
     1921 actgataaac caatggttcc aataccagaa taagcatcaa taaccacgtc atcttttttt
     1981 aactctgcaa agtcaatggc tgtttgatag agtttctccg ccatttcagt attgacttgg
     2041 taaaaggctg ggccagcgat ttggaagtca tttcccaaca tctggtccgt aatatagtct
     2101 tgaccataaa gagtgcacca ctccttacca aaaatcgcat tggtattctg gtcgttgata
     2161 ttttgcatga cagacacaat ctctgggaac tgcttgataa cttgttcaat caattggtca
     2221 acacgaaaaa cttttggacg agttgtcacc aaaacgacca tgatttgtcc tgaatagtga
     2281 ccacgacgca ccacaagatt ccgaatcaat ccagactgtt ccttttcgtc ataaggtttt
     2341 aaatcaaaac gacggagcag gtctcgaaga gctactacga cttggtcaat gacaggatcc
     2401 tggataaaga aatcttcaag gggcatgagg ttgtgcgaat tcttacggaa aaatcctgtt
     2461 tccaagacac cattcactcg acgaacgggc acctgcgcct tattgcgata cttgactgga
     2521 tgttccatac caagcgtttc agcaacttct acatctgcaa ttccagcaat cttgtagaga
     2581 ctgtccttga cttgcttggt tttaaacttg agctgttctg gataagaaag gtgtcctaaa
     2641 tccgcgattc ctgaacgcag gtaagccaaa tctagatctt gattacggtg tagtgactgg
     2701 acaaggtatt tttcaacttt tccaaagcca atctttttat tgaccttgag gacacgcatg
     2761 agaatttttt cactcggtaa agcattctct acaaaaaaga ccaaaccatc taccttggca
     2821 actcctgccc cttcatgggt caaatcaaca atttcaactt ctacaatatc atttttcttt
     2881 aacattcttt tctctttcta ttggccgaca aaaaagacgg caacgttacg attaccatcc
     2941 attataccat gaaatttctt aagaaccaaa actcttgaag aagttgacaa gggcttgcca
     3001 gagggagctt aagaagttac caccgtcctc tagcgcctta tccgcatcaa agttaaggtt
     3061 gatattttta aaactgtcgc cagcttgtga tacgatgctt tgtttaaggt catttagggt
     3121 tttagtgaaa tctgcattgc tgaggatatc actctttgag agattcaagg caaaattgat
     3181 gatgatattg atctggtttc ctgttatgac ctgatcaagt ttgtaatttt ttaaggtatc
     3241 ttcaacaatc ttgcggacat cttcttctgt cagatttccc ttgctttctt tagctttggc
     3301 gagtcctgac ttgatatcag ctagggcaac gtttaattta ttagcatcat agcctgattt
     3361 gtccttgttt tcagcattga tatctgacaa agcctttagc tcttcttgag ccaaatcttt
     3421 attggcttgc ggcaccttgg ctccattagc ttctagcgaa tagtagatcc cagccaaagc
     3481 actctcacct gtaactggaa taggggctgc tacagtgatt ttggcatgtt ccatacccag
     3541 cgttactgct gcgtttcggt acatatcctg agtcacctta gtgatatttt ctggtgtttc
     3601 aatcttgacc tcaagtggcg atttgtcacc tagcttttga atcttggctg atgaatacaa
     3661 ctgtaagcta gagtcattgg ccacattcat gattttagaa taaacatcag gtgtcatggt
     3721 cttgagttct ttggtatctg ttgaggcatt gtagcccagt tttttaagag tttgattttt
     3781 ttggtcttca gatagggagg aacctaggac atattcaggt tggacatagg tttcatcgat
     3841 aaccttttga acatctgttg ctgcatggac gctattcata gctgttactg cccacaagac
     3901 cgcagcactg gtcagaaaga gtttctttct catagggaat ttcctccttt acttttctag
     3961 agtaatatat ctatcttaaa gaaaacttat aacaaaaaca cctggtctag ccagatgttg
     4021 aaaagagagt gaaacatttg atgatgtaaa ggttaagtcg tacctgtcta gaataataat
     4081 agtttcctcc atttacatag agttcagcac cgtgaaaaat ggaaatgggg tgaatataac
     4141 tataagtctt tccagtcgta ttaccaagca agggggcaac agtctcacga gagtactgtt
     4201 tggctagagc caaggtattt tccttgccat tttgggcgat aaaatcgata taggcaggtc
     4261 caaaattata ggcttgaaca gctgtccaga tatctacccc cttcttctgc gccagataga
     4321 gattgcctgt cagagtttga atgccttgcc gaatgctaga ggcattatca ttgatggtgt
     4381 tggttgaacc acttgcagac tcactagact gcataacatc gccttctttt ccttttgttt
     4441 cagtataaat catagcaagc acaagctctt cgtttgctgg ggtgtctttt tcactcaaga
     4501 tttctcgcac catgggttga taggtcatga cttgtttgac atcttgatga acgcggtaag
     4561 ctttatagcc agcaaaaagg aagactgcta gtacaagcac tcttcgaatt cgtttaaaca
     4621 ttatttactt tggatatcct cgatattttt gattaagata gagtaggttc cattttcctt
     4681 ttggataaac tcaacagact cggcgtcttg atagacgtta ttgggaacga tgagctcaat
     4741 tccatttgat aaggagagtt tttggttttc aaatttcttt aattggcgac tggcatcaat
     4801 ttcatcaaat tgaacaggtt ctggtacggc ttctttgact tggtcaataa agctcaaacg
     4861 agccgtcaga ttgttgtcaa aaaggtcatt agccaatttc tcaggtgaca attcattgct
     4921 ttcttctagg ttgttgaaaa tcgctgattt gaccttggat tgaaattgaa aatcatctgt
     4981 gttaaaagat tcagcaattc tctgggctgt tttttccagt tccttgatag attttttagg
     5041 agaaatctta ggagcgacag caagaagatt atctgaaaaa tagttcaaaa aagtcccgtt
     5101 gtacttgatt cgtttttcaa tcaggtgata cttgcgactc tgaagattga ccaccaaggc
     5161 ctcgtcagca cccgttccaa atccaggcag gttattctga gtcagcttga ttggattatc
     5221 aacttctcct ccgaggtggg tcaaggtctc ccgcagggca attcgcaaga aagcgaaatg
     5281 ttctacacct tctttagaaa attgaacaaa aatcaagtca ttggtcttga gattttcaga
     5341 aatgctaaac tcctctttcc agagattagc cagcgttact gatgtctcca acaaatcgtc
     5401 tgtaatatga ttgaagaagg gattttcttc ttcgaaaatc ccagtcttgg cttcatctga
     5461 atacacatgt tcaatttttt tacgtaggta ttcttcgatt tttggagtaa tattgagaaa
     5521 cttatctgct aagaacagct cggtatcatc cggactgaac tggtgaataa tggctttctt
     5581 aatataaatg tccataaaag ttttattcct cgtataatgg gaaggcatct gtcaattctt
     5641 tgactgcact tctcacttct tctaatacag cctcattttc tgaattctta agggttttaa
     5701 tgatgagttc agccactttg cgactttctt cttcaccaaa tccacgtgca gtaatagctg
     5761 ctgctccgat acgaatccca cttgtcttga atggtgacaa ggtttcgtaa gggattgaat
     5821 ttttatttag ggtaatattg acttcatcca gcaagttttg agcaactttt ccgttttcta
     5881 caaccttagt cacatcaaca aggaagagat ggttttcagt tccacctgaa ataatacgga
     5941 aatcagggtc ttgcaagaag acatctgcca tagccttgct gttcttaatt acattggcag
     6001 catattcctt gaaggctgga tccaaaactt ctttgaagga aactgcctta gccgccacaa
     6061 catgctctaa aggaccgccc tgaatacctg ggaaaatagc tgaattgatt tttttagcaa
     6121 gttcttcgtc attggtcaaa atcaaaccac cacgaggtcc acgaagggtt ttgtgggtcg
     6181 ttgttgtagt gatatgagcg tatggcactg ggcttgggtg aagaccagct gcaaccaagc
     6241 cagcgatgtg ggccatatca accataagct tcgcaccgac agcatctgcg atttcacgga
     6301 attttgaaaa gtcaataatt tgagaatagg ctgaagcacc agctacaatc agttttggtt
     6361 ttacttcttg ggcttgtttc aagatagcat caaagtctaa gagttccgtt tcaggatcaa
     6421 cactataaga aacaaagttg taggtttgac cagagaagct aacaggagcc ccatgagtca
     6481 aatgaccacc tgatgccaaa tccattccca taaccgtatc acctggctca atcaaggaca
     6541 tgtaagccgc acagttggcc tgacttcctg agtgaggttg gacattggca aatttagcac
     6601 cgaaaatttc ttttgcgcgt tcaatagcaa gagtctctac aacgtctact acatcagttc
     6661 caccataata acggcgtcct gggtaaccct cggcatattt atttgtcaag atagaccctt
     6721 gagctgccat aacagccttg gaaactacgt tttccgaagc aattaactcg atattatttt
     6781 gttggcgttc ttcttctttg gcaatagcat tccagagatc agcatcatat gctttaaaat
     6841 catctttgtc aaaaatcata ggtcttctcc tttattgtgt gactagtcca ttagtttgat
     6901 tttacaataa gaaaatcaaa ctaaaagatg cgaataaacc gtttctgcat tttatcacaa
     6961 gtatagccaa ctttttcata aaatgcatga gcacccagac gatgattggc agaatttaag
     7021 cggataaacc cataaccaca tcttttggct tcttgttcca acccttgtag taaactttta
     7081 ccgatacctt gaccttgcgc ttgaggtgaa actgctaaag ctaagatatt aaatcctgct
     7141 ttggaataga gtgattcgta aacttcagcg tggacatatc caagtaagac atgattagct
     7201 gcatcctcat agccaagtag gaaatgatgg gaatcctgag acagtctagc tagttggcta
     7261 gccgtttcct ctggactaaa agtataaccc aaagcctctt ggttgatgtc acatatcgct
     7321 ttcacatctg tttcttgcaa atctcttagc atttcaagcc tcctcaaaag aaatctctgg
     7381 caaccgagca agaatatctt ctcgtttaat tgcgccttgg cgtaagattt tcaccttgtc
     7441 tccagacaaa tccacaatag ttgaatcctg tccagttaga aaagcatcgt cttccagacc
     7501 cagaacctct tggtcaaaat ccttcagaat ttgttcaaag gttacaccac ttgcctgacc
     7561 tgagatattg gcagacggcc caatcaaggg acctgtctct cgaattaaat ccagtgtgat
     7621 agggtgactg ggcatccgaa atccaatagt tgcaaggtca gaatttaccc aatagggaac
     7681 tcggtcattg gcttcgagaa taatggtcaa gggacctggc aaaaaggtct ctacaagttt
     7741 ttgtagataa gttggctgat tcttagaaaa gtgcaagata tcctcgaaag aggcgatatt
     7801 gagattgagt gccttatctc taggacgacg tttgagttgg taaacatggt caactgcttt
     7861 ttcatctaag gccttggcaa aaagaccata aacagtctct gtaggtagaa cgacagctcc
     7921 accattttcc aactcttgtc taatcctgtc catcatcaac cacaaccatc ctattttgac
     7981 caaattggtc tttgagtgtt cgaacttttt tttcaggaag atgttttcta aaaagttcgg
     8041 gaacactttg accttgcttg tatccaattt caaggtaaat cttaccacca tccttgagat
     8101 agtcttttgc atcttccgca attctacagt aaatagctag gccatcctcg tctgcaaaga
     8161 gagctagatg aggctccgaa tgcaaaacat tcaagcctac ctctgactca tcttcacgag
     8221 agatataggg tggattggat acaattatat catatttttc agaaatttct gcaaaacaat
     8281 cagatttttt aaaaaatata ttaagatttt gatcgctagc attctctgat gcaagctcta
     8341 aggcctcttg agaaacatct gctgctgtca ctgaccaatc tggtctattt tttgctagag
     8401 cgagagcaat agctccacta cctgttccaa tatccagaac tgagagattc gtctcaagat
     8461 tttcagttag aataagctcc actaactcct ctgtttctgg acgaggaatc aaaacccgtt
     8521 catccacctt taaatgcatt ccataaaaat ctgcctgtcc aatgatgtac tgagctggct
     8581 tgtgagctgc tagttgctgg taaatatctt ctacaaattg tttttcttcc tctgttgtca
     8641 cctcctgctg gagggcaaaa ataaagtctg taaaagatag atttttcaga ctacgataga
     8701 caaaagagag gctttccgct tcctctcctt gtcttatcaa ctcttcttca aaatttgaaa
     8761 ataattgagc taatttcatt atttgtttaa ttcttctagt ttttgtgttt ggtcataaag
     8821 caccaaggca tccacaactt cgtccaattt accagacaaa atcgtatcta gtttttggag
     8881 ggtcaagccg atacggtggt ctgtgacacg gttttgaggg aagttataag ttcggatccg
     8941 ttctgaacgg tcaccagtac cgattgtcga cttacgctca gcgtcttgtt catcctgagc
     9001 aatctgagca aagtggtcag cgacgcgtgc acggataatc ttcatagcct tctcacggtt
     9061 cttctgctgg gtacgttctt cctgcatctc aaccttgata ttggttggca agtgaacgat
     9121 acgaacggca gtcgcaacct tattgacgtt ctgtccacca gcacctgatg cgtggtaaat
     9181 atcaacacga agatcttttg gatcgatatc gtattctact tcttcgactt caggcatgac
     9241 aagaactgtg gcagttgagg tatgaacacg accttggctt tctgtcacgg ggacacgctg
     9301 cacacggtgg gcacctgatt cgtacttaag cttagagtat acagactgac ctgaaaccat
     9361 agcaaccact tctttaaacc caccgacacc attcatagag gcttccatga cttcaaagcg
     9421 ccagccttgg gcttccgcat acttttggta catagttagc aaatctccag cgaaaagtgc
     9481 cgcttcgtct ccaccagctg ctccacggat ttcaaggatg atattcttgt catcgtttgg
     9541 atcctttgga aggagcaaaa ttttcagttt ttcttcatat tcttcttttt cagccttggc
     9601 atctttgagt tcttgcttgg ccatttcttc caagtccgca tctccgcctg attccttaat
     9661 catctcttcg gcatcgacga tattttgaag gacttgttta tactcacggt aggctattac
     9721 ggtatcacga ttggaagctt cttcttttga aagctccata aaacgcttgg tgtctgaaac
     9781 gacatcaggg tcactcagca attctcctag ttcttcataa cggtcttcta cagcttgtag
     9841 ttgatcatag atgttcattt ttcttcattc tccttattga tttcaggggc aaaataatgt
     9901 ttacggcaaa ccgagatata ggtttcatta ccaccaattt ggatctgttc tccatcgtaa
     9961 acgggcagtc catcctgtgt tcgcaacacc atggtcgcct ttttcttgca atactgacag
    10021 atggtcttga tttcgtcaat cttgtctgct aaaagcaaga gatatttgga accttcgaac
    10081 aattcattgc gaaagtcatt tttcaagcca aaagccatga cgggtatgtc taactcgtcc
    10141 acaacacgag ctaggtcata aacatggtgg cgtttgagaa actgggcttc atcgaccaac
    10201 acacagtaag gtttttctgg taggcctcgg atatagccaa agatatccgt tgtttcctca
    10261 atcgcaaggg cagggcgttt catgccaatt cgactcgaca catagccaac accgtcacgc
    10321 gtatccagag ctgaagtcat aatcacaaca ccttttcctt gctcctcata gttataggcc
    10381 accttgagaa tctcgattgt ctttccagag ttcatggtcc cataacgata atacaactgt
    10441 gccatgtttc ttgcttcacg tccatttcta aatttttgct acattctagt atatcataat
    10501 tttcttaagc tttaaacggc aaaatgtggt aaaatggaag aaatcaaaac tagtggagga
    10561 agctattatg ccatttgtac gcatcgattt atttgaagga cgcacgctcg agcaaaagaa
    10621 agctcttgct aaggaagtaa cggaagcagt tgtccgcaac actggagccc ctcaatctgc
    10681 tgtccatgtc atcatcaacg acatgccaga aggaacttac ttcccacaag gggaaatgcg
    10741 tactaaataa gctagcttaa gcagaattgc ttaggctttt tcaatctcca agtagcattc
    10801 attgaagaaa tatcctaaat ttgttacaat ttgaaaagaa acttggagaa tttccaagaa
    10861 aagagctatt aattaaagga aacattatga ttacacgtga atttgatacc atcgctgcta
    10921 tctctactcc actaggtgaa ggggctattg gtattgtccg cctgagcgga acagacagtt
    10981 ttgctattgc gcaaaagatt tttaaaggaa aagacttgaa caaggttgcc agccacactc
    11041 tcaactacgg tcacattatt gatcctctga ctggtaaagt catggacgag gttatggttg
    11101 gggctatgaa gtctccaaag accttcactc gtgaggatat tatcgagatt aacacccacg
    11161 gtggtattgc ggtgaccaat gagattctcc agctagctat ccgtgaagga gctcggttgg
    11221 cagaacctgg tgaatttacc aaacgtgcct ttttaaacgg tcgcgtagat ttgacacagg
    11281 ccgaggcggt gatggatatc atccgcgcca agacagacaa ggccatgaac atcgcggtca
    11341 aacaacttga tggttccctt tctgatctta tcaataatat ccgtcaagaa atccttaaca
    11401 cacttgccca agttgaggtc aatatcgact atcctgagta tgacgatgtt gaggaagcca
    11461 ctactgctgt tgtccgagag aagacaatgg agtttgagca attactaacc aagctcctta
    11521 ggacagcacg tcgtggtaaa atccttcgtg aaggaatttc aacggctatc attggacgtc
    11581 ccaacgttgg gaaatcaagc cttctcaaca acctcttgcg tgaggacaag gctatcgtaa
    11641 ccgatatcgc tgggacaaca cgagatgtca tcgaagagta cgtcaacatc aatggtgtac
    11701 ctctcaaatt gattgataca gctggtattc gtgaaacgga tgatatagtg gaacaaatcg
    11761 gtgttgagcg ttcgaaaaaa gccctcaagg aagccaactt ggttctacta gtgctaaatg
    11821 ccagtgaacc actgactgcg caagacagac aacttcttga aattagccaa gataccaatc
    11881 gcattattct acttaataaa accgacctgc cagaaacgat tgaaacttcg aaactacctg
    11941 aagacgttat ccgtatttca gtccttaaaa accaaaacat cgacaagatt gaagagcgaa
    12001 tcaacaacct cttctttgaa aatgctggct tgattgagca agatgctact tacttgtcaa
    12061 acgcccgtca catttccctg attgaaaaag cagttgaaag cctacaagcc gttaatcaag
    12121 gtcttgagct ggggatgcca gttgatttgc ttcaagttga cttgactcgt acttgggaaa
    12181 tcctcggaga aatcactggg gatgctgctc cagatgaact catcacccaa ctctttagcc
    12241 aattctgttt aggaaaataa gaaaaatcca tgatccttca ttcggtcatg gattttattg
    12301 tctttattag taatctggtc ttaagacccc tgttacagtt gccttagttg cttcgtagtc
    12361 gccatctacg acaaccttga taatgcgttt ggcatcttct tctggtgctg gaacaagagg
    12421 tagacgagtg ggtccagctt caaatcccat atagttaaga attgccttaa ctggagcagg
    12481 acttggataa gagaagagag cattaacctt aggaatgaat ttacgctgaa ttgctgcggc
    12541 tttcttcata tcgctttctg caatggcagt aaacatctcg tgcatttcat ccccatttgt
    12601 atgagaggca acagaaataa ccccatccgc cccaaggttc atggcatgga aagcatctcc
    12661 atcctcacct gtataaatca agaactcttc aggcttgtgc tcaatcaagt aagccatatt
    12721 agccaagcta gtacattctt tgacaccgat aatatttgga tggtcagcca agcgaagcat
    12781 ggtttctgga gtcaattcga caactacacg ccctggaatg ttatagataa taattggtag
    12841 gtcagaagca tctgcaatag tcttaaagtg ctgatacatc ccttcttgag aaggtttgtt
    12901 gtagtaagga acaatagcaa gcccagctgc gaaaccacca aattccgcta cttctttgac
    12961 aaactcaata gagtcacgcg tatcattagt acctacaccc gcaatcaaag gaacgcgtcc
    13021 attgacaacc ttttgtacag ccgcaaacaa ctccaactcc tcatcgtggg tcaaagttgg
    13081 actctcagca gtcgttcctg cgagaagaat tccatccgta tgatgggcca ataaatgctc
    13141 aatcaaggct ggaatagcat caaagttaat agaaccatcc tcatgaaagg gggtaataaa
    13201 ggctgtaatg attttacatt cttttaaatc ttgataagac atgaaaacac ctctctattt
    13261 caaagaagga gttcatctga actcctaaac gatatgacta ttttaattca aatttcaatt
    13321 cggctgttgg acgaaccaat ccacgttcat gaagagtttc agcaatctga actgagttcc
    13381 aagcagcacc tttgagaagg ttatctgaaa caacccacat gtgaattcct ttttctgcat
    13441 ccaagtcttt acggatacga ccaacaaagg tatcacgcga accaactgca ttgatagctt
    13501 gaggatagat ttgatgagct acatcatctt caagaacagc acctgggaag gctgcgatag
    13561 ctgcttttac ttcttcgatt ggagccactt cttttgtttc gatataaaca gactcagagt
    13621 gagctgacaa gactggaata cgcacacatg ttgcagatac tgcaatgcta tcatcttcca
    13681 taattttctt agtttccttg gtcatcttca tctcttcgta cgtgtaatca ttatcagtga
    13741 aaacatcaat ttgtggaaga gcgttaaagg cgataggata atgtttcttg tcaccacctg
    13801 aaggcaaaat ttccgcatgc aaatcacatg gtttcacacc atcattcaag acttcacgaa
    13861 gttcacgttg tgtctcaaga attgctccca taccagcacc tgaaacggct tgataagttg
    13921 aaacaatgat acggtccaag ccccattttt ggcgaaccgg ctcaagagcc accatcattt
    13981 ggattgttga acaattaggg caggcaatga ttccgttgtg ggcatcaagt gcatgagcat
    14041 tgacctctgg aacaaccaaa ggaacatctg gattttgacg gaaataagat gtattatcca
    14101 ctactaccac gccagctttt actgcgtatg gtgcatactt agctgatgta gaactacctg
    14161 ctgaaaagag agcaatatca actccttcaa aagctgtttc agtcgtttct tcaattgtaa
    14221 tatcttgatc tttaaatttc aatgacttac ctgctgaacg tgcagaagca aggtaacgga
    14281 ttttatcgat tggaagtgtt gattcttcca acatttttat catctgagca ccgacagcac
    14341 ctgtcgcgcc gactacagca actgtatatc ccataaataa cctctttcgg aattttctaa
    14401 aaatttctat aatagaagta ttatactact ttttccatga attgcaaagc tttttcatca
    14461 ttttttggaa aataaaaatc ccagtcgcta gactagggac taagaggcat cttcatgtga
    14521 tgagcaggtt cacacaactc atcaaggtcc gctcctgcgt tatgacctcc ttatgctcaa
    14581 tagtagtccg aagactacct atcgactcat cgcatattct atattactag agatacttga
    14641 ttttgtcaat aagaaatttt ttcgatcgag tataacaaaa aactctcgta ttcaagagtt
    14701 tccctataca tatcatgcta attgccggga tcgaaccggc gacctcatcc ttaccatgga
    14761 tgcgctctgc caactgagct aaatcagctt acttaagaag tatactatat tcagaaaaac
    14821 ttgtcaagtt tccttagaaa ttttccatag gaaaaagcca ggtaagaact acctagctta
    14881 tcttcttcta tttacttaaa tcaattcgac gaccaatttt accaataata atcgccccaa
    14941 taatcaatga agcaaattca ccgattcctg ttgtaaacca agtaaggaag aatggtaatt
    15001 ctgctacaat atttaactct gcagcgatag taaacatgga aattgaaaag aggattgaaa
    15061 agaagaaatg atcttttcga atcaatccgt taaagaggta atccttgcta tattttgcaa
    15121 aaagccaaac acctaaactg aggaatacta aggttgaacc accaccaaca aagacatcta
    15181 gcagtccgaa gctaaagaaa ttagcaatca tacaaccgat ggtaactccg atgatgtact
    15241 taggattgta aaaagccata aagttcatca tttctgaaat acgaaactga taagcaccat
    15301 agctgatggc atttaggggc ggtgtgacag tcaaaacgac gtagatagca gcgacgattg
    15361 caatatctgc aatatcacga atagttaatt ttttcatctt ttctcctttg gcggttgccc
    15421 gcgtgtaata tgcttggtga aagaagctaa gcaccaaggg ttgctttatt caaccctact
    15481 agtatagcac aatagcctgc tttatgctat acttaacaca tgaaaattcc tattcaaaaa
    15541 ttttttaaca atgaaatctt agcctatctc ttttttggcc ttgcgacaac tctagtttcg
    15601 attctctcac gactagtcat ttatcaacta agtcatcagg aactcctggc tactgcccta
    15661 gcaaatatta tcggtatcct atttgccttt atcacaaatg atacgattgt atttaagcaa
    15721 aaaaagaaaa atagacttat ccgtttagtg aaattttctc ttgctcgcct ttctactttt
    15781 ctgttagact tgtttttaac ttttctcttt gtaacccaat ttcctcacat tatagggcaa
    15841 ttcgtaactg aaaacattga taagataaat gctattgaaa caataattgc acaaatattc
    15901 attattatca tcaattatat attgagcaag gcctatattt ttagaaaata atgctccatt
    15961 tatgagcctt ttaattgcct tctataatga tttaggatac aatgaaacac gaaacattga
    16021 aaggaaaaca gtatgttaaa aaatctaaaa tcgttcttgc ttcgaggaaa tgttattgac
    16081 cttgctgtcg gtgttgtaat tgcctctgct tttggtgcta tcgttacttc acttgtaaac
    16141 gacattatca ctcctcttat tttaaatccc gctttgaaag ctgctaaagt tgaacgtatc
    16201 gctcaacttt cttggcatgg agtcggctat ggtaacttct taagtgctat tatcaatttt
    16261 atctttgtgg gtaccgccct cttctttatt atcaagggca ttgaaaaagc acagaaactg
    16321 actggcataa agaaagaaaa aactgccgaa aaaaaaccaa ccgaattgga agtccttcaa
    16381 gaaataaaag ctctccttga gaaaaaataa tcgattaaaa ggatctagcg caaagctaaa
    16441 tccttttttc tttactcttt gggtaacttg cctgcttttt caagcatttt tttgatcaga
    16501 taaggcatct taacattctc ccgccctttt ttctcaatca gttttttcac aaattctggc
    16561 atttgtaaat cttcagattc agctaaaatg tttttcgtct cgtctgaagg aactaactca
    16621 tcaaaggtct cttcttctgg gagaaattcc ttaaactctt gattttcatt gactctaact
    16681 gtattgacca aagcatcaat caaacgagaa tctgtatttg gcattggtgg acgatggtag
    16741 tttaccccaa attcctggca taagtcataa cattctacat cattgtcaaa caagacctca
    16801 atatgctcac tgatgaaact aataggtaca aaaatataat ggtctggatg ttctgtctgt
    16861 tctctgagat actccaaaac atctggttta atccatggaa taccaatatc actctcactc
    16921 tgccaagtgt tggtatattg ttctgaactc aagcccagtt tttcagcgac tagcttgcta
    16981 ttttcgaaaa tttggtctat ataaggatca ccaaagtcca aggcaaaaat gggcacacta
    17041 tgggctgaaa agatgacttt aaagctgtct tgctttactt cttcttttaa aatcttagca
    17101 atttcatctg cccaatagtt taagagcact tcttcctgat accagtcctt aatgaccaaa
    17161 aattgaattt gtttgctttc taaaaatttt tcatagccca tgacagagta gaaagaataa
    17221 tggggctcca aaatcaagca gatacattct tcaacaccat cagtttccat ctgcttgatc
    17281 acgtctggaa taaagggacg agaaaatttg ttggcaaagt agataccgta ctcctcccct
    17341 aaacgttctt tgactaaatt gacctcctca cgtgtaatcc gctgcaaagg cgtcccaccg
    17401 atacgaatat agttgtcata gagagtctgg atttcgtggt cttggggtct aactccacga
    17461 cgaatgtttg taaagaattc tgctactcct tcaaaactaa tctcctctgg agatccaaag
    17521 gtcatcatta atatggcttt tttcatgtta tcatccttat gatattattt tctctatcca
    17581 ttctatcatg aaagaaaaaa atagtaaacg tttcctacgt ctactatttc ttttgctctt
    17641 ttgttttttt atctcgtctt ataattagga tgataaggac aagaagtaag aggacgataa
    17701 taaggagtag aaaggctaga atgtaaatcc aatgactggg aattccgtga tcgaaatacc
    17761 gtgttcctac tgcttcccca ctttcatcct gtgctacttt caccggtgca tccgttattt
    17821 tagctaaaag gatatgtcgt ccattagtta tgttaaggaa acatctcgct tgtacttggc
    17881 tttacttagc agatattgat agtaagcctg gtgttcctca tccttggaac tcaaggttcg
    17941 ataaatctcc gtgtcatagg catccacttc taaaatccca aaaatttcaa gaccacgttc
    18001 tcgaccattg tagtagatag aaccgtagcg atgctggtcg aagaattcct tatcagcaaa
    18061 tttcttaatc tcaccgaaca tagcccctga agccatagag tgtccgtaga tgatcgtatt
    18121 aaaatcagta aagttgggat taaagcgata gtcgagaaaa attgatccca ttatcgtata
    18181 atcgccaaag gcattgcggt caaggtattt gacattatcc tgactttgta gaagcggata
    18241 gtctaccttg gtcccatcaa ggctaatcca accgcaaaca tctttgttca agtgctgtag
    18301 ggtttcaaaa cctgtgctcg aagcatcctt ttcaatagga ttatagtgat catagtcact
    18361 tgcttctact actctctgcc aactaaaaag agctacaaaa acacagaaga ataccagaaa
    18421 tacgttttta aatcgcgctc ttttttgaac cgtcatcagc actcctttct atgcgagatt
    18481 tcttaaaagg aaaggaggcg ggacaaaacc gcctcttttc tattcaccct tagtcagtaa
    18541 aagggtctgc ttcttgcatt ttttttactc tctcttctac gacgtaggat caagtagagg
    18601 acaaggagta agaaaatcaa gagcaagaac aatacaaaca agataaggta ccaaatccat
    18661 agtgggattg atgagaggaa acgtccaaga gacgagtcat caaagacact gtatggaaat
    18721 ggttttgatt tttttgtatg gaaagtattt ttagggacgg tgtctgtaat ctttgcgact
    18781 acgatatgac gaccattggt cacatcgaga aaacaggtac tgagtaggat gatacgatca
    18841 ctcggtgaga gtgagatatc ccgcttgtgc atggcgactg agagcaggtg gtctagatag
    18901 gcctgctggc ggtcctcacc ctgtattcct ggatcataga tgttaaagtc ataggcatca
    18961 acctccaaca tctcaaagat ctcgagccct ttttccacac cattgtagta tatactaccg
    19021 taacgatgct ggtcaaaaaa ttcctgatca gcaaacttag ccacatcacc aaacatgacc
    19081 ccattttcta cgtggtgccc gtagataatg gtattaaagt cttcgaactt aggattattt
    19141 cgtgcatcga gaaagatagc gcctgtcgct gcaaactcac ctttggagtc cttgttgaga
    19201 tacttttcat tgtccttggc ttggactaag ggatagtcga tattggtgcc atagacattg
    19261 atccaaccga ggacttcggg attgagttct tggagtttgc tgaagcctga aaaactggcc
    19321 agctcatcct gttgcgtcgt gacaggtcga taagcttcgt actcacttga cgaagctaag
    19381 gagtagactt ggttggaatc ccaaagggcg tagaaaccaa agagaaagat caaagctgca
    19441 aaaatgagca gcaagtgatt gatcacccca tccacagcaa gaacgagacg cctagacaga
    19501 ctcttttttg gtttctcacg cttggttttc atcatctgcc cccagccgtt taggcttctc
    19561 tacgtttttt agacaagaca acaaatccag ccaaaccaag accaatcatc aaaatgaatg
    19621 gaaggttatc aatcaagaga ccagtaggag taacgtcgtc gattttgtta gtaactttgt
    19681 tgtcgttttt cttttcacct atgaggatat ctgttaatgt aaaatctaca tttttttgtc
    19741 cttgagatgt ttgttctgca ccatttgtag tataaattga tgaatctgta taacctgcta
    19801 ctccagtttc agttactgta tatttagaac ctgctggtag ttgttcaact gtaaatgttt
    19861 caccatcttt aagagtaaaa ttgtactcaa ctgtatctgc tggggtcact actgccaaca
    19921 cctctgactt agatccatgt tttactataa tattcgtaac aggggtttct gctgttttat
    19981 ttgtacttgg aagttgaatc ttgatatgga attggaaatc tcttgtttta tcccctgaag
    20041 ctccatcaac ttttttagta attgttaatg ctttcgcatt ggggtctact tgactcggat
    20101 catcaggatt aggctcctta cttgcgtctt tggtatatgt gttatcaaat aaattataaa
    20161 cgccttgttc acttggttct actttagggg cgttagattt attattttcc ttaaagtata
    20221 ctgatgaaat atagacacca ccatttactt tattcttaac aataacgtgc atttcatatg
    20281 tacgtttgtc gtatctcatg gcatcaattg ttttaccatt tttggtaatc gcctgccatc
    20341 cagtttttgc ttccgctaca tcataaacgt attcaccagc atggccataa gcaactcccg
    20401 aaaaaatgtc ttctgttgct ttttgaatct tatcagcagt tgggtgatca tttttattgt
    20461 attctacatt tctatctgga attgcaactc cggtttgata tggcgcaccg ttagaagatt
    20521 gtcctgtttt ttctgtaaac ttaaatgtaa atgtcgctgt tggtgttgtt attccctctg
    20581 caatattcaa cgttttatta atcttcacaa cagcattatt ttcaccattt gctttggtta
    20641 ttgctgaatt atcatccgca aaagtcggga cacctctgaa tacggacaaa gcggttatag
    20701 ctgcaatgct tgcagtgaat agctttttaa agaatgtttt tttcatgatt atttcttttg
    20761 tttttttatt ttcttttttc attatgatca tcaaaagcct cgtcttctaa tgactgttac
    20821 aactttgcct tgagtatcct gtatagggat ggttccaaaa gcacgactgt ctacagccgt
    20881 tgttcgattg tccccgagga caaaaagttg tcctgctggg actttcatcg ggaaggttgc
    20941 cccttcctta tagagcagcg tttctttgta gatatcttgc tcttgttgag gagaaccgtt
    21001 gatgatgaga ccattttcgt ttatatcgat tgtacttcct tcggttgcta tgacacgcgc
    21061 cactctttcc ttacctttat aactatagac tagcaaatca ccaatcgaat agcgtttatc
    21121 caacctataa tagacgacca agtcgccatc ttttaaggcg ggcttcatgc catcgtcatt
    21181 gtatcttaat aatccaaaga cgaaaaagta aaggatggct agtacaaatc caaccatcag
    21241 aagtttactg actaagtaaa ggatatctcc ccagacactc ggcggagact tatcccgatt
    21301 gacttgtgtt actggtttct tatgtttctt tttaagcagc atcacttcct cctattcacc
    21361 acaaggtgac caagtaagat gataaagaag atccctccta gaggaagaac gactccaagc
    21421 acgagagtgc tactcaagaa gtcaattccc gtttcaggta cgctgttttt attattcgtg
    21481 actgtcgcag acttatttgc atcaagagtt ccttcttttt tatcatagga cacctgatac
    21541 ccacgagacg aacttgcttc ttcttcgata ctataacgag catttagagg aaggtcgaga
    21601 atcttgatgg ttttatcttt ctttagatca actgtcgcct taccattggt gaattgtagc
    21661 gttgtttttt gattatttac tattgcacta tacgatccat tcaatggttt attttgcgca
    21721 tcctttacgt taatggtaat cttaaaggat tgcagaagat tagcaaaagc acctgtaact
    21781 ttttttgtga ctgaaagtgt cggaagtctg tggttggtga cgattgtttg aacatcctct
    21841 gacaaagtcc cctcttgttt ttcataggtg acatgatatc ccgttctaga gttctctact
    21901 tcttccacct tatagtgggt atcacgaggc agataactga gggcagtttc ctgactattt
    21961 ttgagagaaa tctgtgcttt cccgttagtc actgttgtat tcccaaactt gccgttaatc
    22021 ggcttgccat ccttatctga aaaggtaaca ttaattgtga aagatttatt aggtgattgt
    22081 tcaccttcta ggattttctt tacggtgaga cttggaagct gtcggtaaat aactttgaag
    22141 gatggtttct ctttcgtacc tgtcttttga acttcgactg tgtatcccgg agcgtctggt
    22201 gctttcagtt cgtagtcata tcccttagct acctttgcaa aactagtatt ttcagtaaaa
    22261 ctattcgttt gaactggact agtgaccttt cgataggaat cctttatact tccatctttc
    22321 ttttggttta agtttaattc gacactaggt ggacgatttg ctgatggatt tgattttcca
    22381 tccacacctt tccactcaat ctctacagga accgtcaatg gatctgacgg cttgaaagtg
    22441 ggcttctcag aatagtcttt tattttggta cgtgaggtcc caataccata ggaataggca
    22501 acttttgccc ccttgttgga gtagagttta gtagcatcgg cttcttcggc atcatcacta
    22561 gtaagtgtct tatcacccgc aatcgcatca aatgcctctt ggctagaggt gacagtaaac
    22621 ttgagaacgt acttggcgtc atcctccaaa gtgtaactcg gattaaactt ggctgttact
    22681 tccactaatc cctgttcgtt cttcttagtt tcaatcgtaa cttgattgtc attcagttct
    22741 tgctcgttac catccttgat tttgacgaca cgaaggtgtg aagcatcacc aggtaacagc
    22801 tgcacgtact tggacaagac atctgatata gttacatggt gtacgcctag aggtagaatt
    22861 ttatctgtga tttctttgaa tttttgttgc aagtcatttt cattattggc agaaaatatt
    22921 tcgttgggga ttccagaatt ataaccactg atatatcctt taagagatgt gatactatcg
    22981 tttgaaccta tataatatct gaatttgatt gaataaaagc catctatttt tggagctatt
    23041 aaactagata tattcagcat tcctctttct aaaccagagg taaaccaata tggagtatca
    23101 atcatacgtc ccacatttgg attagaataa tagttatata ttgttctccc actattagac
    23161 tcgtaataca tattagcttc gccatctgac agcagaataa ctactttttt tgccccagcc
    23221 cttgcacttt gcaacaatct ttgagcttca gttaacccag catttatatt tgtcccagtg
    23281 ccaatgcccg cgtccatacc ataagaacga ctagagtcag caattgttaa cgaactaaca
    23341 atattttttg agctattaga atccgtgctc caagatacta aagttttagc atcatcatat
    23401 gaagagatat ttgaatacca accagctcaa tttggccaag ttccatattg ataactcaga
    23461 taatattcat tataataacg gtcattatac tgattatcaa tctttccggc aaaaccaact
    23521 atagacagac ggttttggga attagaaaga attgtatcaa tgagcccctg acgaccattc
    23581 acacctttca gtgtatgttt tagtgcttca atcctactaa tgtatcgtct actagagtaa
    23641 gaccacacat ctcgctcttc catactccct gaaagatcgg caaccaagac tacatccaag
    23701 ggttctgact gggtctccgt tcccagttta gatgtgatat ccagtgacaa ctcatactgg
    23761 tctttttgcc ctgatatcgg agtaatcgtt ttgtgcagag ttgtctgagg ttcagttatt
    23821 gaatctgcac gtaaagaatt aattggtgca cacaaaaaaa gaatagcgag aaagataact
    23881 aaactactgg taaaatattg aatcttctta aaatcatatt gaacgttcat gctatctccc
    23941 ttgctagaat atgttttaat ctgatactat ataaatctga gacttccata agataattgt
    24001 ataataatat taacttcgtg tcaattaatg tgtttgaaaa catgttatta taaattacaa
    24061 aaaagtatga ttcttctttg tttttcaact ttttctgtgg taaaatggaa aaaatagtaa
    24121 aaaatttcat aaaataaaga tgcatatatt tattctaatc gctcgaaaat ttcttttgaa
    24181 agtcttctga atttgaatta ttatattttt tcaaaattca taaaatttct caaatcatat
    24241 ttttccgaag ttttgtattc tattttatga taaaaaagga gtttttttat gacttatcca
    24301 aatctcttgg accgcttctt aacctacgtt aaggtcaaca cgcgctctga tgaacactct
    24361 actactactc caagtacaca gagtcaggtt gacttcgcaa caaatgtcct aattcctgaa
    24421 atgaaacgtg ttggactgca aaatgtttac tatctaccga atggttttgc tattggaacc
    24481 ttgccagcca acgatccgtc tttaacacgt aagattggtt ttatatcgca catggatact
    24541 gctgatttta atgctgaagg agtcaatcca caggtaattg aaaactacga tggtggtgtg
    24601 attgaactag ggaattctgg tttcaaactc gatccagccg acttcaagag tcttgaaaaa
    24661 tatccaagac aaacactcat cacaacagat ggaacaacct tgctaggtgc tgatgacaag
    24721 tcaggaattg ctgaaattat gacagccatt gaatatctaa ctgctcatcc tgaaattaag
    24781 cactgtgaga ttcgtgttgg ttttggtcca gatgaagaaa tcggtgttgg tgccaataaa
    24841 tttgatgcag aagattttga tgtggatttt gcctacactg ttgatggtgg tccactaggt
    24901 gaacttcagt acgagacttt ctcagccgct ggtgctgaat tgcatttcca aggccgtaat
    24961 gtccaccctg gtactgccaa agggcagatg gtcaatgccc ttcagctagc aattgatttt
    25021 cataatcaac ttccagaaaa tgaccgacct gagttaactg aaggttacca aggtttttac
    25081 catctaatgg atgtgacagg tagtgttgag gaggtgcgtg caagctacat cattcgtgat
    25141 tttgaaaaag atgcctttga agcgcgtaaa gcatccatgc aatctatcgc tgataagatg
    25201 aatgaagaac ttgggagcga ccgtgtcact ctcaacttga cagaccagta ctacaatatg
    25261 aaagaagtca ttgaaaaaga tatgactcca attaccattg ctaaagccgt tatggaagat
    25321 ctaggtatca cgcctattat cgaaccaatc cggggtggaa cagacggctc taagatttcc
    25381 tttatgggaa tcccaactcc gaatatcttt gcaggtggcg aaaatatgca cggacgtttt
    25441 gaatacgtta gccttcagac tatggaacgt gcagttgata ccatcattgg catcgtagct
    25501 tataaaggct aaaaagacga ggtggctcag ctacttcgcc tttcttttta ttctactggt
    25561 ttttcttgat ttccagtagt tgtagaagat tctgttgttt cattttctga agttgattca
    25621 gcaggtttag aatctcttgt attgcttggt ttgttttcgt cgctagcagt ttcaatgtta
    25681 gattctgcag ttgcgtttgg ttggttctca gcactggtgt tatcactatt tgcttcagca
    25741 tttcttgctg gacttgtttc ttcacttgcg ctaacttttg actggatttg atgattcaaa
    25801 actagaatag cttttgtcga ttcaagtaaa gctgttttgt ctttactatt agcagaaagt
    25861 tgatctaata atgcatccac cttatcaaag tccgcatcag atccattatt actttctaaa
    25921 taagagtgaa gcgacatgag aatatcgtag agtttttgat agagtacaag tgtctgagaa
    25981 tcttgctcag cattttcctt ttcttgttga agggcgctag cgatacgagt caaaacatct
    26041 tttacctgac tgtttacttc atccaagtct gcatcagcct tgtttgtggc agcttttaga
    26101 ttttctactt cttctgccaa ggattgtctg attccttctt catggatttg ttccaagagt
    26161 tgatttgcct tgttcaaaag actttctact tcttccttgc tatctgtcgc agattattgg
    26221 ttgctatcta ccatgtactc ctaaaacagg agagttataa tccaagatta caaggcctta
    26281 cagaaataag aaatccagat aagacaatgt tcgtccaaga cgctattcgc ttcgcacagc
    26341 agcacggatt caatatgctt taattttaaa gtttaggtgt caagacctct ttttagtgtg
    26401 cccaaaattt agagaagtaa tcaatcaact aacttttatt tttttcaaac tttcagtaaa
    26461 ctgacctaaa gctaactcaa tctgtctttg tagatgcttc tgctatcagc tagaagttga
    26521 tctacttttg ccaagactgc cttctcatca aaagttccag gttgatagtt ggattgcagg
    26581 gatggaatct tgtttttcaa agccgcttca tatcccttag tttgaacctt gatgtagtga
    26641 ttgtggtcgc catgaggaat cacaaaacct tctgaatctt cacttataat tcgattggca
    26701 tcaaaaacca taaccatctt cttcctcatg gtggacatgt agtgacggat tacttaatac
    26761 agaactagaa gaacttccta cctcttccgt gttagagtgt gatgggggat tgttaagaga
    26821 tgacttagga atatagtgat agtgttcccc atgtcttact atataagcat cacctatatc
    26881 tctgacaata tcattagggt taaagacata tgtggctgct aattcacctg ccgacaagtc
    26941 actctcagga atgaaatgat agtgaccacc atgtggtact attagtagat tgaaatagaa
    27001 tatgagcaaa ttgataaggg gattttaaag taatttctaa caatgattta gaaactatga
    27061 tgtgctattc taaattcaac tcactatata taaccatcat cggtagtata acgtccctgt
    27121 aattttgcta cagatacttc tgcactagct cctttatcgt ctttaccatg ttcttgtttt
    27181 tggcgattga tttcatcttt tgttcgtaca ttttctgcat gagcttgatc tttaaggtaa
    27241 acataatact ttccatctac cttaataata tatcctccct taacctaact gacaatatct
    27301 tgatctttcg gctgatagtt gggggctttc attaatggct cttcactaaa gagcgcatca
    27361 aaaggaactt taccattata gtagtgataa tgatcgccat gagaagttac ataaccttga
    27421 tctgtaatct taataacaat ttgttttgct tgaattcctt ctttttgact aacctagtct
    27481 ggagtcaaat tttcagtctt cttagtgtct ttattactgt ttacatatga aacacgattt
    27541 ttatctgtat tggcctgtta gctatgttgg ttcagagcat aaacacacag acttaaggaa
    27601 aggataacaa cagatccagc tgctatatat ttctttttaa atttcataat tacctcattt
    27661 ctataattat ttatatgatg tcttcattat taaatgatta tagaaattaa ttaaccaatt
    27721 aattaactag taaatattcc acctcttttt aagttgtatg tcaagaaatt ttatatatta
    27781 ataataaaat gaaattctcc caaagtcaga gttttatttc taacttttga gagaacttca
    27841 tttttgattc agactttttc tactgctatt ccttacgcta tgagatcaga taaattcttt
    27901 tttatcactt ctccacttgg caatcttaat tcaatcgttc catccatatt gaatataaca
    27961 ctatctaagc ctaatccgta actagctgta aatttttcta atttttcttg tacaggatct
    28021 actgctggag cttcctctaa tgctggatct aacatagggt cactccccac attcccttct
    28081 ggattcaaca ttccattatc cgttgagttt tctggtttta caggtttttc gtttggtgcc
    28141 tctggtaaag aatctgctgg tttattttct gttggttggt tctcaactgt tccagtagat
    28201 acttttccat tttcagatgg tttattttca ccatttcctt gaggtgcttc tcctgtaaaa
    28261 tctgccatat tctttttaat gacttctccc gatggtaaat ataattcaat tgttccgtcc
    28321 atattaaaca agacattttc tagcttcatc ccataacttt cagcaaattt tgctactttt
    28381 tcttgtacag gatccactgt aggaacttct tctaacgttg aattactagt actattccca
    28441 gtttcagaaa gtttttcttt ttctaccttc tcactagtct ttggttcttc taccttttca
    28501 tcaagttttg agttttcttg tgctttattc cttttaaatt gtggtagaat acttggttta
    28561 tcagtttgat tttctttttc caagataggt acttccacaa tataagtcga ttgattgtcc
    28621 aaataagcat ttgccatgaa ggttacagga attttatttc cggccgttct ggttgttcct
    28681 tggtttaatt tcggaatcgg taatttgatt tcaccaactt tatagttatt ttctaaataa
    28741 gcatttccat gaaattcatc aaacactctg actaaagcat cagttccttt aggcactgca
    28801 aattgagggt tcactcttaa ataagtatcc cctgcatgga aaggatagaa aatcgtttga
    28861 ctggccattt tgtaagctaa agaggttgga actgtaaatg taccatcata acttacttct
    28921 ggataatctt ttgaagcgat agtatactta aatgtttgtc ctggtaaata aggttgatct
    28981 aattcaaagt ttgcaatatt ccctactcct tctccaaata ctttaccaga tactttctcc
    29041 aatacttttc catctggtgt tattaatttt actagcatat tgatacctaa ttttttctcc
    29101 aattcaggcg gaaaactaaa agaaacgcgt ttttgaccat tggctagagt aaagttttga
    29161 ttattaaacg tactattttt taacaaatta acaacattcg ttaattcttc tccagtataa
    29221 actttattcc cttctttttt agcaactcct tcttcgggtt taaacagttc atagttactg
    29281 tgagaatgac caattccaac cggtttatgt tcatcaatcg gatctgcatg atggtgatct
    29341 ccatgcggat aaataatcgc atttttttct ttattcacga caatactttc acgtttgaca
    29401 ccatattgtt tcataatgcc agcaattttt tcttcgattt ttttatctaa atctttcatt
    29461 tctttggcat tacttggata atcctgttca tgagatgaca aagaatctaa tccattatga
    29521 ctagttttaa cttcctctaa atgtttttgc gcagccttaa tttgctcttc tgtcaagtcc
    29581 ttcttgaaga aataatgatt gtggtctccg tgactcatga caaaacctga ttcatcttca
    29641 gcgataatac gattagcatc aaatccgtat ccatcttctt catgtttctc atgtgaagtt
    29701 cctggattga ttggaagaga tggagaaggt gttgctagac tattgtttgg aagagtcggt
    29761 tgcccaattt gatttgattt tggaatgtaa tggaaatgat caccatgtct tacaatataa
    29821 gctgtagccg tttcttcaac gatatctttt ggattaaaaa tataaccatc agatgctgaa
    29881 gagagctcct tacttgtcgt taaagaagaa ggattgcttg aaagactgcc tagactagac
    29941 actacttcat taggttttgc atttgtagaa actgtagaac cagttccact gataggcacc
    30001 attctggcaa tcttttcttc taaggcagaa agcttgctgt aaggaataaa gtggtaatgg
    30061 tcgccatgcg gaatcgcaac tccatttggt gtacgactga taatcttagc agggtcaaag
    30121 accaggccat ctgattcact gtaacgttgg gcgctaggtg aatcatagag ttccttcaaa
    30181 agactctgga gattttcaga tttatttgct ggcttgctag ttgatccttt tgctacagat
    30241 tgcgtgttat tgtcactagc tgttgaagaa tagcttaact gactcggttg catatttttt
    30301 ccagccagat gtgctttagc tgctgctaat tcactagcag ataaatcgct tttgggaatg
    30361 tagtgatagt gacctccatg aggaacgata taagcattac ccgtatcttc gataatatca
    30421 gctggattaa agacataacc atcatttgtc gtatatcgtc cctgagacct tgctacagca
    30481 acattagagt taaccttctc attatctttg acatgttctt gtttttgacg attgatttca
    30541 tctttagttc gaacattatc agcatgagct gcatctttca ggtagacata atattttcca
    30601 tcgaccttga tgatataacc acccttgact tcattgacaa tatcagcgtc tttaagttga
    30661 tagtttggat ccttcatcaa gagttcttca ctaaagaggg catcataagg aactttccca
    30721 ttatagtaat gatagtggtc accgtgtgac gttacatagc cctgatctgt aattttgatt
    30781 acaatttgct cggcctgaat tccttctttc tggctaatct ggtctggtgt caagttttca
    30841 cttttctgac ttgactggct gccatctaca taagagacac gattattgtc cttattttcc
    30901 tgcgaacgat gctggtttag tgcataggca catagactca aggatacgat aacagctgat
    30961 ccagctgcta tatatttttt actgaatttc ataaatccct ca
//
LOCUS       DAVBBO010000022        30073 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ST1
            SAMEA2066453-rid20184263.denovo.022, whole genome shotgun sequence.
ACCESSION   DAVBBO010000022 DAVBBO010000000
VERSION     DAVBBO010000022.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2066453
            Sequence Read Archive: ERR351777
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 30073)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 30073)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980402.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980402.1
            Genome Coverage       :: 176x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:17:33
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,141
            CDSs (total)                      :: 2,104
            Genes (coding)                    :: 1,953
            CDSs (with protein)               :: 1,953
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 16S)
            partial rRNAs                     :: 1 (23S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 151
            CDSs (without protein)            :: 151
            Pseudo Genes (ambiguous residues) :: 0 of 151
            Pseudo Genes (frameshifted)       :: 73 of 151
            Pseudo Genes (incomplete)         :: 76 of 151
            Pseudo Genes (internal stop)      :: 40 of 151
            Pseudo Genes (multiple problems)  :: 32 of 151
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..30073
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2066453-rid20184263.denovo.022"
                     /strain="ST1"
                     /db_xref="taxon:1313"
     gene            51..1100
                     /locus_tag="VQU30_000988"
     CDS             51..1100
                     /locus_tag="VQU30_000988"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000229779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LLM class flavin-dependent oxidoreductase"
                     /protein_id="HET2447113.1"
                     /translation="MVELGISTFGEITELEGTGQTYSHAERIRQLVAEIELADKVGLD
                     VYGIGEHHRADFAVSAPEIVLAAGAVNTKKIRLTSAVSILSSMDPIRLFQQYATIDAL
                     SNGRAEIMAGRGSFTESFPLFGYDLKDYDSLFDEKLDLLQLVNEKTKLDWQGRLTQTI
                     AGKEVYPRPVQDKLPLWIATGGHVESTVKIAQAGLPIVYAIIGGNPRYFKKLIQAYRE
                     IGSEAVHADKDLKVGAHSWGWIAEDGEQAVKDYFHPTKQVVDAISKDRPHWQELRYEQ
                     YLEQVGSNGAMFVGNPDQVAEKLIRMIEDLGLDRFMLHLPLGSMPHDQVLRAIELFGT
                     QVAPKVRAYFAMKEA"
     gene            complement(1200..5042)
                     /gene="spuA"
                     /locus_tag="VQU30_000989"
     CDS             complement(1200..5042)
                     /gene="spuA"
                     /locus_tag="VQU30_000989"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001860626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG-anchored pullulanase SpuA"
                     /protein_id="HET2447114.1"
                     /translation="MRKTPSHTEKKMVYSIRSLKNGTGSVLIGASLVLLAMATPTISS
                     DESTPTTNEPNNRNTTTLAQPLTDTAAGSGKNESDISSPGNANASLEKTEEKPAASPA
                     DPAPQTGQDRSSEPTTSTSPVTTETKAEEPIEDNYFRIHVKKLPEENKDAQGLWTWDD
                     VEKPSENWPNGALSFKDAKKDDYGYYLDVKLKGEQAKKISFLINNTAGKNLTGDKSVE
                     KLVPKMNEAWLDQDYKVFSYEPQPAGTVRVNYYRTDGNYDKKSLWYWGDVKNPSSAQW
                     PDGTDFTATGKYGRYIDIPLNEAAREFGFLLLDESKQGDDVKIRKENYKFTDLKNHSQ
                     IFLKDDDESIYTNPYYVHDIRMTGAQHVGTSSIESSFSTLVGAKKEDILKHSNITNHL
                     GNKVTITDVAIDEAGKKVTYSGDFSDTKHPYTVSYNSDQFTTKTSWRLKDETYSYDGK
                     LGADLKEEGKQVDLTLWSPSADKVSVVVYDKNDPDKVVGTVALEKGERGTWKQTLDST
                     NKLGITDFTGYYYQYQIERQGKTVLALDPYAKSLAAWNSDDSKIDDAHKVAKAAFVDP
                     AKLGPQDLTYGKIHNFKTREDAVIYEAHVRDFTSDPAIAKDLTKPFGTFEAFIEKLDY
                     LKDLGVTHIQLLPVLSYYFVNELKNHERLSDYASSNSNYNWGYDPQNYFSLTGMYSSD
                     PKNPEKRIAEFKNLINEIHKRGMGAILDVVYNHTAKVDLFEDLEPNYYHFMDADGTPR
                     TSFGGGRLGTTHHMTKRLLIDSIKYLVDTYKVDGFRFDMMGDHDAASIEEAYKAARAL
                     NPNLIMLGEGWRTYAGDENMPTKAADQDWMKHTDTVAVFSDDIRNNLKSGYPNEGQPA
                     FITGGKRDVNTIFKNLIAQPTNFEADSPGDVIQYIAAHDNLTLFDIIAQSIKKDPSKA
                     ENYAEIHRRLRLGNLMVLTAQGTPFIHSGQEYGRTKQFRDPAYKTPVAEDKVPNKSHL
                     LRDKDGNPFDYPYFIHDSYDSSDAVNKFDWTKATDGKAYPENVKSRDYMKGLIALRQS
                     TDAFRLKSLQDIKDRVHLITVPGQNGVEKEDVVIGYQITAPNGDIYAVFVNADEKARE
                     FNLGTAFAHLRNAEVLADENQAGSVGIANPKGLEWTEKGLKLNALTATVLRVSQNGTS
                     HESTAEEKPDSTPSKPEHQNEASHPEHQDPAPEARPDSTKPDTKVADAENKPSQATAD
                     SQAEQPAQEAQASSVKEAVRNESVENSSKKNIPATPDRQAELPNTGIKNENKLLFAGI
                     SLLALLGLGFLLKNKKEN"
     gene            5459..5872
                     /gene="rpsL"
                     /locus_tag="VQU30_000990"
     CDS             5459..5872
                     /gene="rpsL"
                     /locus_tag="VQU30_000990"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S12"
                     /protein_id="HET2447115.1"
                     /translation="MPTINQLVRKPRKSKVEKSKSPALNVGYNSHKKVQTNVSSPQKR
                     GVATRVGTMTPKKPNSALRKFARVRLSNLIEVTAYIPGIGHNLQEHSVVLLRGGRVKD
                     LPGVRYHIVRGALDTAGVNDRKQGRSKYGTKRPKA"
     gene            5892..6362
                     /gene="rpsG"
                     /locus_tag="VQU30_000991"
     CDS             5892..6362
                     /gene="rpsG"
                     /locus_tag="VQU30_000991"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285383.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S7"
                     /protein_id="HET2447116.1"
                     /translation="MSRKNRAPKRDVLPDPLYNSQLVTRLINRVMLDGKRGTAASIVY
                     GAFEQIKEATGNDALEVFETAMENIMPVLEVRARRVGGSNYQVPVEVRPERRTTLGLR
                     WLVTIARLRGEHTMQDRLAKEILDAANNTGAAVKKREDTHRMAEANRAFAHFRW"
     gene            6787..8868
                     /gene="fusA"
                     /locus_tag="VQU30_000992"
     CDS             6787..8868
                     /gene="fusA"
                     /locus_tag="VQU30_000992"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor G"
                     /protein_id="HET2447117.1"
                     /translation="MAREFSLEKTRNIGIMAHVDAGKTTTTERILYYTGKIHKIGETH
                     EGASQMDWMEQEQERGITITSAATTAQWNNHRVNIIDTPGHVDFTIEVQRSLRVLDGA
                     VTVLDSQSGVEPQTETVWRQATEYGVPRIVFANKMDKIGADFLYSVSTLHDRLQANAH
                     PIQLPIGSEDDFRGIIDLIKMKAEIYTNDLGTDILEEDIPAEYLDQAQEYREKLIEAV
                     AETDEELMMKYLEGEEITNEELKAGIRKATINVEFFPVLCGSAFKNKGVQLMLDAVID
                     YLPSPLDIPAIKGINPDTDAEEIRPASDEEPFAALAFKIMTDPFVGRLTFFRVYSGVL
                     QSGSYVLNTSKGKRERIGRILQMHANSRQEIDTVYSGDIAAAVGLKDTTTGDSLTDEK
                     AKIILESINVPEPVIQLMVEPKSKADQDKMGIALQKLAEEDPTFRVETNVETGETVIS
                     GMGELHLDVLVDRMRREFKVEANVGAPQVSYRETFRASTQARGFFKRQSGGKGQFGDV
                     WIEFTPNEEGKGFEFENAIVGGVVPREFIPAVEKGLVESMANGVLAGYPMVDVKAKLY
                     DGSYHDVDSSETAFKIAASLSLKEAAKSAQPAILEPMMLVTITVPEENLGDVMGHVTA
                     RRGRVDGMEAHGNSQIVRAYVPLAEMFGYATVLRSASQGRGTFMMVFDHYEDVPKSVQ
                     EEIIKKNKGED"
     gene            8972..13363
                     /locus_tag="VQU30_000993"
     CDS             8972..13363
                     /locus_tag="VQU30_000993"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000071418.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PolC-type DNA polymerase III"
                     /protein_id="HET2447118.1"
                     /translation="MSNSFEILMNQLGMPAEMRQAPALAQANIERVVVHKISKVWEFH
                     FVFSNILPIEIFLELKKGLSEEFSKTGNKAVFEIKARSQEFSNQLLQSYYREAFSEGP
                     CASQGFKSLYQNLQVRAEGNQLFIEGSEAIDKEHFKKNHLPNLAKQLEKFGFPTFNCQ
                     VEKNDVLTQEQEEAFHAENEQIVQAANEEALRAMEQLEQMAPPPAEEKPAFDFQAKKA
                     AAKPKLDKAEITPMIEVTTEENRLVFEGVVFDVEQKVTRTGRVLINFKMTDYTSSFSM
                     QKWVKNEEEAQKFDLIKKNSWLRVRGNVEMNNFTRDLTMNVQDLQEVVHYERKDLMPE
                     GERRVEFHAHTNMSTMDALPEVEEIVATAAKWGHKAVAITDHGNVQSFPHGYKAAKKA
                     GIQLIYGMEANIVEDRVPIVYNEVEMDLSEATYVVFDVETTGLSAIYNDLIQVAASKM
                     YKGNVIAEFDEFINPGHPLSAFTTELTGITDDHVKNAKPLEQVLQEFQEFCKDTVLVA
                     HNATFDVGFMNANYERHDLPKISQPVIDTLEFARNLYPEYKRHGLGPLTKRFGVALEH
                     HHMANYDAEATGRLLFIFIKEVAEKHGVTDLARLNIDLISPDSYKKARIKHATIYVKN
                     QVGLKNIFKLVSLSNTKYFEGVPRIPRTVLDAHREGLILGSACSEGEVFDVVVSQGVD
                     AAVEVAKYYDFIEVMPPAIYAPLIAKEQVKDMEELQTIIKSLIEVGDRLGKPVLATGN
                     VHYIEPEEEIYREIIVRSLGQGAMINRTIGHGEHAQPAPLPKAHFRTTNEMLDEFAFL
                     GEELARKLVIENTNALAEIFESVEVVKGDLYTPFIDKAEETVAELTYKKAFEIYGNPL
                     PDIVDLRIEKELTSILGNGFAVIYLASQMLVQRSNERGYLVGSRGSVGSSFVATMIGI
                     TEVNPLSPHYVCGQCQYSEFITDGSYGSGFDMPHKDCPNCGHKLSKNGQDIPFETFLG
                     FDGDKVPDIDLNFSGEDQPSAHLDVRDIFGEEYAFRAGTVGTVAAKTAYGFVKGYERD
                     YGKFYRDAEVERLAQGAAGVKRTTGQHPGGIVVIPNYMDVYDFTPVQYPADDVTAEWQ
                     TTHFNFHDIDENVLKLDVLGHDDPTMIRKLQDLSGIDPNKIPMDDEGVMALFSGTDVL
                     GVTPEQIGTPTGMLGIPEFGTNFVRGMVDETHPTTFAELLQLSGLSHGTDVWLGNAQD
                     LIKQGIADLSTVIGCRDDIMVYLMHAGLEPKMAFTIMERVRKGLWLKISEEERNGYIE
                     AMKANKVPEWYIESCGKIKYMFPKAHAAAYVMMALRVAYFKVHHPIYYYCAYFSIRAK
                     AFDIKTMGAGLEVIKRRMEEISEKRKNNEASNVEIDLYTTLEIVNEMWERGFKFGKLD
                     LYRSQATEFLIDGDTLIPPFVAMDGLGENVAKQLVRAREEGEFLSKTELRKRGGLSST
                     LVEKMDEMGILGNMPEDNQLSLFDELF"
     gene            13465..13728
                     /locus_tag="VQU30_000994"
     CDS             13465..13728
                     /locus_tag="VQU30_000994"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelB/DinJ family
                     antitoxin"
                     /protein_id="HET2447119.1"
                     /translation="MSKMSISIRLDSEVKEQAQQVFSNLGMDMTTAINIFLRQAIQYQ
                     GLPFDVRLDENRKLLQALTDLDQNRNMSQSFESVSDLMEDLRA"
     gene            13721..13999
                     /locus_tag="VQU30_000995"
     CDS             13721..13999
                     /locus_tag="VQU30_000995"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013904578.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system YafQ family
                     toxin"
                     /protein_id="HET2447120.1"
                     /translation="MLKIRYHKQFKKDFKLAMKRGLKAELLEEVLNFLVQEKEHPARY
                     RDHSLTASKHFQGVRECHTQPDWLLVYKVDKSELILNLLRTGSHSDLF"
     gene            14020..14172
                     /locus_tag="VQU30_000996"
     CDS             14020..14172
                     /locus_tag="VQU30_000996"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000776615.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2447121.1"
                     /translation="MKLRIFAEDKPAKKVFEYQLELADRTILLSTALLSGAIALAGIF
                     SALKEK"
     gene            14194..15435
                     /locus_tag="VQU30_000997"
     CDS             14194..15435
                     /locus_tag="VQU30_000997"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000243957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase"
                     /protein_id="HET2447122.1"
                     /translation="MVLPNFKENLGKYAKLLVANGINVQPGHTLALSIDVEQRELAHL
                     IVKEAYALGAHEVIVQWTDDVINREKFLHAPMERLDNVPEYKIAEMNYLLENKASRLG
                     VRSSDPGALNGVDADKLSASAKAMGLAMKPMRIATQSNKVSWTVAAAAGLEWAKKVFP
                     NAASDEEAVDFLWDQIFKTCRVYEADPVKAWEEHAAILKSKADMLNKEQFSALHYTAP
                     GTDLTLGLPKNHVWESAGAVNAQGEEFLPNMPTEEVFTAPDFRRADGYVTSTKPLSYN
                     GNIIEGIKVTFKDGQIVDITAEKGDQVMKDLVFKNAGARALGECALVPDPSPISQSGI
                     TFFNTLFDENASNHLAIGAAYATSVVDGAEMSEEELEAAGLNRSDVHVDFMIGSNQMD
                     IDGIREDGTRVPLFRNGNWAN"
     gene            15445..15675
                     /locus_tag="VQU30_000998"
     CDS             15445..15675
                     /locus_tag="VQU30_000998"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000901571.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GlsB/YeaQ/YmgE family stress response membrane
                     protein"
                     /protein_id="HET2447123.1"
                     /translation="MLGSMFVGLLVGFLAGAMTNRGERMGCFGKMFLGWIGAFLGHLL
                     FGTWGPVLSGTAIIPAILGAMIVLAIFWRRGS"
     gene            15898..16620
                     /locus_tag="VQU30_000999"
     CDS             15898..16620
                     /locus_tag="VQU30_000999"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397198.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA pseudouridine synthase"
                     /protein_id="HET2447124.1"
                     /translation="MRLDKFLVACAVGSRTEVKNLLKAGRVTVNGKKEKSAKLQIDEK
                     IDEIRFDGQVLEYEEFVYYMMNKPKGVISATEDPKHRTVLDLLDDLARSKEVFPVGRL
                     DIDTHGLLLLTNNGQLAHVLLSPKRHVDKTYQAQVKGIMTQEDVETFIKGIPLKDFTC
                     QPARLEILSTDAEKNQSQIRVTIAEGKFHQIKRMVGYCGKEVVDLQRLTMGTLVLDEN
                     LERGEWRRLTKEELEILRANII"
     gene            16837..18171
                     /gene="pepC"
                     /locus_tag="VQU30_001000"
     CDS             16837..18171
                     /gene="pepC"
                     /locus_tag="VQU30_001000"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000991632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase C"
                     /protein_id="HET2447125.1"
                     /translation="MNAIQESFTDKLFANYEANVKYQAIENAASHNGIFAALECRQSH
                     VDNTPVFSLDLTKDKVTNQKASGRCWMFAALNTFRHKLISQYKLENFELSQAHTFFWD
                     KYEKSNWFLEQVIATSDQELTSRKVSFLLQTPQQDGGQWDMVVSLFEKYGVVPKSVYP
                     ESVSSSSSRELNAILNKLLRQDAQILRDLLVSGADQATVQAKKEDLLQEIFNFLAMSL
                     GLPPRKFDFAYRDKDNNYKSEKGITPQEFYKKYVNLPLEDYVSVINAPTADKPYGKSY
                     TVEMLGNVVGSRAVRYINVPMERLKELAIAQMQAGETVWFGSDVGQLSNRKAGILATD
                     VYDFESSMDIKLTQDKAGRLDYSESLMTHAMVLTGVDLDENGKSTKWKVENSWGDKVG
                     TDGYFVASDAWMDEYTYQIVVRKELLTAEEQAAYGAEPIVLAPWDPMGALAE"
     gene            complement(18227..19138)
                     /locus_tag="VQU30_001001"
     CDS             complement(18227..19138)
                     /locus_tag="VQU30_001001"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000136863.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose/fructose/sorbose transporter family
                     subunit IID"
                     /protein_id="HET2447126.1"
                     /translation="MTEKLQLTKSDRKKVWWRSTFLQGSWNFERMQNLGWAYTLIPAI
                     KKLYTKKEDQIAALERHLEFFNTHPYVAAPVMGVTLALEEERANGVEIDDAAIQGVKI
                     GMMGPLAGIGDPVFWFTVRPILGSLGASLALTGNILGPLLFFVAWNLIRMSFLWYVQE
                     IGYKAGSEITKDMSGGILQDITKGASILGMFILAVLVQRWVNIKFAFDVSKVQLDEKA
                     YIHWDKLPEGSKGIQEAFAQVGQGLSQTPEKVTTFQQNLDMLIPGLSGLLLTLLCMYL
                     LKKKVSPITIILALFAVGIVAHVLHIM"
     gene            complement(19162..19965)
                     /locus_tag="VQU30_001002"
     CDS             complement(19162..19965)
                     /locus_tag="VQU30_001002"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000022712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose/fructose/sorbose transporter subunit
                     IIC"
                     /protein_id="HET2447127.1"
                     /translation="MSIISMVLVVVVAFFAGLEGILDQFQFHQPLVACTLIGLVTGHL
                     EAGIILGGSLQMIALGWSNIGAAIAPDAALASVAAAIIMVLGGDFTKTGIGVAQAVAI
                     PLAVAGLFLTMIVRTISVGLVHTADAAAKKGDFGAVERAHFIALLFQGLRIALPAALL
                     LMVPTETVQSILSAMPDWLKDGMAIGGGMVVAVGYAMVINMMATREVWPFFALGFVLA
                     AVSDITLIGFGAIGVAIALIYLHLSKTGGNGGGGAATSNDPIGDILEDY"
     gene            complement(19993..20982)
                     /gene="manX"
                     /locus_tag="VQU30_001003"
     CDS             complement(19993..20982)
                     /gene="manX"
                     /locus_tag="VQU30_001003"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000021981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose transporter subunit IIAB"
                     /protein_id="HET2447128.1"
                     /translation="MSIGIIIASHGEFAAGIHQSGSMIFGEQEKVQVVTFMPNEGPDD
                     LYAKFNNAVAAFDAEDEVLVLADLWSGSPFNQASRVMGENPERKFAIITGLNLPMLIQ
                     AYTERLMDAAAGVEKVAANIIKEAKDGIKALPEELNPVEEVASAAAAPVAQTAIPEGT
                     VIGDGKLKINLARLDTRLLHGQVATAWTPDSKANRIIVASDNVAKDDLRKELIKQAAP
                     GNVKANVVPIQKLIEISKDPRFGETHALILFETPQDALRAIEGGVPIKTLNVGSMAHS
                     TGKTLVNTVLSMDKEDVATFEKMRDLGVEFDVRKVPNDSKKDLFDLINKANVK"
     gene            complement(21215..22234)
                     /gene="adhP"
                     /locus_tag="VQU30_001004"
     CDS             complement(21215..22234)
                     /gene="adhP"
                     /locus_tag="VQU30_001004"
                     /EC_number="1.1.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000649145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alcohol dehydrogenase AdhP"
                     /protein_id="HET2447129.1"
                     /translation="MKAVVVNPESTGVAIEEKVLRPLETGEALVEVEYCGVCHTDLHV
                     AHGDFGQVPGRVLGHEGIGIVKEIAPDVKSLKVGDRVSVAWFFEGCGTCEYCTTGRET
                     LCRTVKNAGYSVDGGMAEQCIVTADYAVKVPDGLDPAQASSITCAGVTTYKAIKEAKV
                     EPGQWVVLYGAGGLGNLAVQYAKKVFNAHVIAVDINNDKLTLAKEVGADIVINGLEVE
                     DVAGLIKEKTDGGAHSAVVTAVSKVAFNQAVDSIRAGGRVVAVGLPSEMMELSIVKTV
                     LDGIQVIGSLVGTRKDLEEAFQFGAEGLVVPVVQKRPVEDAVAIFDEMEKGQIQGRMV
                     LDFTH"
     gene            complement(22573..23385)
                     /locus_tag="VQU30_001005"
     CDS             complement(22573..23385)
                     /locus_tag="VQU30_001005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000162344.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HET2447130.1"
                     /translation="MTKKIIAVDLDGTLLNSDSQISDFTKRTIKKVAEKGHQVIITTG
                     RPYRMSKDFYRELGLDTPMINFNGSLTHLPDQVWDFEKCLTVDKKYLLDMVQRSEDIQ
                     ADFIAGEYRKKFYITNPNEEIANPKLFGVEAFQPEDQFQPELVTKDPNCILLQTRASD
                     KYALAKEMNAFYQHQLSINTWGGPLNILECTPKGVNKAFALDYLLKIMNRDKKDLIAF
                     GDEHNDTEMLAFAGKGYAMKNANPELLPYADEQISLTNDQDGVAKTLQDLFL"
     gene            23575..24993
                     /locus_tag="VQU30_001006"
     CDS             23575..24993
                     /locus_tag="VQU30_001006"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000359314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NCS2 family permease"
                     /protein_id="HET2447131.1"
                     /translation="MDKLFKLKENGTDVRTEVLAGLTTFFAMSYILFVNPQILSQTGM
                     PAQGVFLATIIGAVAGTLMMAFYANLPYAQAPGMGLNAFFTFTVVFGLGYSWQEALAM
                     VFICGIISLIITLTNVRKMIIESIPNALRSAISAGIGVFLAYVGIKNAGLLKFTIDPG
                     NYTVVGEGADKAQATIAANSSAVPGLVSFNNPAVLVALAGLAITIFFVIKGIKGGIIL
                     SILTTTVLAIAVGLVDLSSIDFANNHVGAAFEDLKTIFGAALGSEGLGALVSDTARLP
                     ETLMAILAFSLTDIFDTIGTLIGTGEKVGIVATNGENHQSAKLDKALYSDLIGTTVGA
                     IAGTSNVTTYVESAAGIGAGGRTGLTALVVAICFAISSFFSPLLAIVPTAATAPILII
                     VGIMMLGSLKNIHWDDMSEAVPAFFTSIFMGFSYSITQGIAVGFLTYTLTKLVKGQVK
                     DVHAMIWILDALFILNYISMAL"
     gene            25046..25753
                     /locus_tag="VQU30_001007"
     CDS             25046..25753
                     /locus_tag="VQU30_001007"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260476.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HET2447132.1"
                     /translation="MKEKNMWKELLNRAGWILVFLLAVLLYQVPLVVTSILTLKEVAL
                     LQSGLIVTGLSIVVLALFIMGARKTKLASFNFSFFRAKDLARLGLSYLVIVGSNILGS
                     ILLQLSNETTTANQSQINDMVQNSSLISSFFLLALLAPICEEILCRGIVPKKIFRGKE
                     NLGFVVGTIVFALLHQPSNLPSLLIYGGMSTVLSWTAYKTQRLEMSILLHMIVNGIAF
                     CLLALVVIMSRTLGISV"
     gene            25848..26822
                     /gene="folP"
                     /locus_tag="VQU30_001008"
     CDS             25848..26822
                     /gene="folP"
                     /locus_tag="VQU30_001008"
                     /EC_number="2.5.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydropteroate synthase"
                     /protein_id="HET2447133.1"
                     /translation="MMKILEGVTDMSSKANHAKTVICGIINVTPDSFSDGGQFFALEQ
                     ALQQARKLIAEGASMLDIGGESTRPGSSYVEIEEEIQRVVPVIKAIRKESDVLISIDT
                     WKSQVAEAALAAGANLVNDITGLMGDEKMAHVVAKAGAKVVIMFNPVMARPQHPSSLI
                     FPHFGFGQTFTEKELADFETLPIEDLMVAFFERALARAAEAGITPENILLDPGIGFGL
                     TKKENLLLLRDLDKLHQKGYPIFLGVSRKRFVINILEESGFEVNPETELGFRNRDTAS
                     AHVTSIAARQGVEVVRVHDVASHRMAVEIASAIRLADEAENLDLKQYK"
     gene            26824..28146
                     /locus_tag="VQU30_001009"
     CDS             26824..28146
                     /locus_tag="VQU30_001009"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000658404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional folylpolyglutamate
                     synthase/dihydrofolate synthase"
                     /protein_id="HET2447134.1"
                     /translation="MKEIENNQWIANYRTDQPHFGLERMVELLALRGNPHLKLKVLHI
                     GGTNGKGSTIAFLKKMLEKLGLRVGVFSSPYLIHYTDQISINGESISEARLEALMADY
                     QSLLEGEAVANLQGTTEFEIITALAYDYFASEQVDVAIMEVGMGGLLDSTNVCQPILT
                     GITTIGLDHVALLGDTLEAIAEQKAGIIKQGIPLVTGRIAPEALTVIDRIAEGKDAPR
                     LAYGTDYQVRHQESVVTGEVFDYTSAVRQGRFQTSLLGLYQIENAGMAIALLDTFCQE
                     DGRELASNDFLGQALEETSWPGRLEIVSRDPLMILDGAHNPHAIKALLVTLQERFADY
                     HKEILFTCIKTKALEDMLDLLGAMPDTELTLTHFADSRATDESVLKEAAKSRNLSYQD
                     WHDFLEQNLTDKKEEKQTVRIVTGSLYFLSQVRAYLMERKNENGYTKD"
     gene            28127..28681
                     /gene="folE"
                     /locus_tag="VQU30_001010"
     CDS             28127..28681
                     /gene="folE"
                     /locus_tag="VQU30_001010"
                     /EC_number="3.5.4.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006155259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP cyclohydrolase I FolE"
                     /protein_id="HET2447135.1"
                     /translation="MDTQKIEAAVKMIIEAVGENANREGLQETPARVARMYQEIFSGL
                     GQTAEEHLSKSFEIIDDNMVVEKDIFFHTMCEHHFLPFYGRAHIAYIPDGRVAGLSKL
                     ARTVEVYSKKPQIQERLNIEVADALMDYLGAKGAFVVIEAEHMCMSMRGVRKPGTATL
                     TTVARGLFETDKDLRDQAYRLMGL"
     gene            28724..29536
                     /gene="folK"
                     /locus_tag="VQU30_001011"
     CDS             28724..29536
                     /gene="folK"
                     /locus_tag="VQU30_001011"
                     /EC_number="2.7.6.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397195.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-amino-4-hydroxy-6-
                     hydroxymethyldihydropteridine diphosphokinase"
                     /protein_id="HET2447136.1"
                     /translation="MDQLQIKDLEMFAYHGLFPSEKELGQKFVVSAILSYDMTKAATD
                     LDLTASVHYGELCQQWTTWFQETSEDLIETVAYKLVERTFEFYPLVQEMKLELKKPWA
                     PVHLSLDTCSVTIHRRKQRAFIALGSNMGDKQANLKQAIDKLRARGIYILKESSVLAT
                     EPWGGVEQDSFANQVVEVETWLPAQDLLETLLAIESELGRVREVHWGPRLIDLDLLFV
                     EDQILYTDDLILPHPYIAERLFVLESLQEIAPHFIHPTLKQPIRNLYDALKK"
     gene            complement(29581..29898)
                     /locus_tag="VQU30_001012"
     CDS             complement(29581..29898)
                     /locus_tag="VQU30_001012"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000886024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF960 domain-containing protein"
                     /protein_id="HET2447137.1"
                     /translation="MAFTNTHMRSASFGIVTSLPDDIIDSFWYIIDHFLKNVFELEEE
                     LEFQLLNNQGKITFHFSSQHLPTAIDFDFNHPFDPRYPPRVLVLDMYGRETILLPEEN
                     DLF"
BASE COUNT         8526 a         5841 c         7006 g         8700 t
ORIGIN      
        1 ttagaataat ttttcaaatt gaaggacaga gatagacaag gagaatcaca atggtagaat
       61 tgggaatttc aacatttggg gaaataacgg agcttgaagg gactggacaa acttacagtc
      121 atgctgaacg cattcgccag ttggtggcag agattgagct ggctgacaag gttggtttgg
      181 acgtatatgg gattggcgag caccatcggg cggattttgc agtatcagcc ccagagattg
      241 tcctggccgc tggggcagtc aataccaaga aaatccgttt gaccagtgca gtcagcattc
      301 tgtcaagcat ggatccgatt cgtttgttcc aacagtatgc cactatcgat gctttgtcaa
      361 atggacgagc ggagattatg gctggaaggg gctctttcac ggaatctttc cctctgtttg
      421 gttatgactt gaaagactac gactctcttt ttgatgagaa attagacttg cttcagttag
      481 tcaatgaaaa gaccaagtta gactggcaag gtcgattgac tcaaacgatt gctggtaaag
      541 aagtttatcc tcgtccagtt caggacaaat tgcccttgtg gatagctaca ggtggtcatg
      601 tcgaatcaac agtgaagatt gctcaggctg gtctaccgat tgtatatgct attattggtg
      661 gtaatccacg ttattttaaa aagttgattc aggcttatcg tgagattgga agcgaagcgg
      721 tccatgctga caaagacttg aaagtgggag cccattcttg ggggtggatt gcggaagatg
      781 gtgagcaggc ggtgaaagat tatttccatc cgactaagca agtggtggat gctatttcca
      841 aagaccgtcc gcactggcag gaattgcgtt atgagcaata tttggagcag gtagggtcaa
      901 atggcgccat gtttgttggc aatccagatc aggtggccga aaaattgatt cgcatgatag
      961 aggatttagg attggaccgc ttcatgcttc atctaccgct tggttctatg cctcatgacc
     1021 aggttctgag agctattgaa ctcttcggaa cacaagttgc acccaaagta cgagcttatt
     1081 ttgctatgaa agaggcttaa taaaaaatcc taatcaagtt tattaggaca acaaatattg
     1141 tacgaaaatt aatcccccga gctataatgc ttgggggatt tttctatagg agggctagtt
     1201 tagttctctt ttttattttt tagtaagaaa ccgagaccaa ggagcgcaag gaggctgatt
     1261 cctgcaaata ggagtttgtt ttcgttttta attcctgtat ttggaagttc agcttgtcta
     1321 tctggggttg caggtatatt tttcttgcta gagttttcta ccgattcgtt tcgaaccgct
     1381 tcttttacag atgatgcttg tgcttcttgt gctggttgtt cagcttgtga atcagctgta
     1441 gcttggctag gtttattttc cgcatcagct actttggtat ctggtttagt agaatcaggt
     1501 ctagcttctg gagctggatc ttgatgttca gggtgagaag cttcattttg atgttcaggc
     1561 ttggaagggg ttgagtctgg tttctcttct gcagttgact catggctagt tccattttga
     1621 gagactcgaa gaacagtagc tgtaagggca ttcaatttca agcctttttc agtccattca
     1681 agtcctttcg ggttggcaat tccgactgat cctgcttggt tttcatctgc caaaacttcc
     1741 gcatttctta gatgtgcaaa ggcagttccc aaattaaatt cgcgagcttt ttcatccgca
     1801 ttgacaaaga ctgcgtagat atcgccgttt ggagcagtga tttgatagcc aatcactaca
     1861 tcctcttttt ccacaccatt ttggcctggg acagtgatga ggtggacacg gtctttgata
     1921 tcttgaagac tcttaagtcg gaaggcatct gtagattgac gaagggcaat caaacctttc
     1981 atatagtcac ggctcttgac attttcagga taagctttac catctgtagc cttagtccag
     2041 tcaaacttgt tgactgcatc actagaatcg taagagtcat ggatgaagta aggatagtca
     2101 aatgggttgc cgtccttatc acgcaacaag tgagatttgt ttggaacctt atcctctgct
     2161 actggagtct tgtaggctgg gtcacggaat tgtttagtac gtccatattc ctgaccggag
     2221 tggataaatg gagttccttg agctgtcaag accatgagat ttccaagtcg taaacgacgg
     2281 tggatttcag catagttctc agccttgctt gggtcttttt tgatagactg ggcaatgatg
     2341 tcaaagaggg tcaagttatc atgggctgcg atgtattgga tgacatctcc agggctgtca
     2401 gcttcaaagt tagttggttg agcaatgaga tttttaaaga tggtgttgac atcacgcttg
     2461 ccacctgtga taaaggcagg ttgaccttcg tttggataac cagatttgag gttgttacgg
     2521 atgtcatctg aaaagacagc gacagtatcg gtatgtttca tccaatcttg gtcagcagct
     2581 ttagtaggca tgttttcatc accggcatag gttctccaac cttcaccaag catgatgagg
     2641 tttggattga gggcgcgtgc agccttgtaa gcttcttcga tagaagcggc gtcatggtct
     2701 cccatcatat cgaaacggaa gccatccact ttgtaggtat caactaggta tttgatagag
     2761 tcaattagga gccgtttggt catatggtgg gttgtcccca agcgtccacc accaaagcta
     2821 gttcgaggtg tgccatcggc atccataaag tggtagtagt ttggttccaa atcttcaaag
     2881 agatcgactt tggctgtgtg gttataaacg acatctagga tagctcccat accacgtttg
     2941 tggatttcgt tgatgaggtt tttaaattct gcgattcgtt tttctggatt cttaggatcg
     3001 cttgagtaca taccagtcaa ggagaagtag ttttgagggt catatcccca gttgtagttg
     3061 ctgttgcttg aagcgtagtc agacaagcgt tcatggtttt tcaattcatt gacaaagtag
     3121 taagacaaga ctggaaggag ctggatatgg gttacaccca agtctttgag atagtctagt
     3181 ttttcaatga aggcttcaaa agtcccaaat ggtttggtca agtcttttgc aatggcagga
     3241 tctgaagtga aatcacgcac atgagcttcg tagataacgg cgtcttcacg agtcttgaaa
     3301 ttgtgaatct taccataagt caagtcttga ggtccgagtt tagctggatc tacaaaggcg
     3361 gctttagcca ctttatgggc atcgtcaatc ttggaatcgt cgctattcca agcagcaaga
     3421 gatttagcgt aaggatcgag tgcaagaaca gttttacctt gacgctcgat ttggtattga
     3481 taatagtagc cagtgaaatc tgtgattccg agtttgtttg tgctgtctag agtttgtttc
     3541 caagttcctc tttccccttt ttcaagagcg acagttccaa ctactttgtc agggtcattc
     3601 ttgtcgtaga caacaacaga aaccttatca gcacttggtg accaaagggt caaatcaact
     3661 tgttttcctt cttcttttag gtcagctccc agtttgccat catagctgta tgtctcatct
     3721 ttcaggcgcc agcttgtttt ggtagtgaat tggtcggaat tgtagctaac agtataagga
     3781 tgttttgtgt cagagaaatc tccgctgtag gtcactttct taccagcttc atcgattgca
     3841 acatcggtaa tagttacctt gtttcctagg tgattagtga tgttggagtg tttgaggata
     3901 tcttcttttt tagcaccgac aagtgttgaa aagctacttt caatgctaga agtgcctacg
     3961 tgttgggctc ctgtcatacg gatatcatgg acatagtatg gatttgtgta aatcgattca
     4021 tcatcgtctt ttaggaaaat ttggctatga tttttcaaat ctgtgaactt ataattttct
     4081 ttacggattt tcacgtcgtc tccttgtttg ctctcatcta gtaataaaaa tccaaattct
     4141 cttgcggctt cattaagagg aatgtcgata tagcggccat atttgcctgt agccgtaaag
     4201 tctgttccgt caggccattg agcgctactt ggatttttca catctcccca gtaccagaga
     4261 gatttcttgt catagttgcc atctgtgcgg tagtagttga cgcgaacagt tcctgcaggc
     4321 tgtggctcgt aagagaaaac cttgtaatct tggtctaacc aagcttcgtt catttttgga
     4381 actagttttt ctacagattt atcgccggtt agattttttc cagctgtatt gttgatgagg
     4441 aagctaattt tcttggcttg ttctcccttt aatttgacat ctaggtaata gccgtagtca
     4501 tctttcttgg catccttgaa ggacaaagct ccgtttggcc agttttcaga tggtttttca
     4561 acatcgtccc aagtccatag tccttgagca tccttgtttt cttcaggaag ttttttgaca
     4621 tggatacgga agtagttatc ttcgatgggc tcttctgcct tagtttcagt tgttactgga
     4681 ctagtagaag tagttggctc acttgaacga tcttgtccag tttgtggtgc tggatcggct
     4741 gggcttgcag caggtttttc ttctgttttc tctagggaag cgtttgcatt tccaggtgaa
     4801 gaaatatcac tttcgttctt accagagcca gctgctgtat cagtaagagg ttgggcaagg
     4861 gtggttgtat ttctgttgtt gggttcgtta gtggttggtg tactttcgtc ggatgagata
     4921 gttggtgtag ccatggcaag caagacaagg cttgcgccga taaggacaga accagttcca
     4981 tttttgaggg aacggatgct gtagaccatt tttttctcag tgtgagatgg tgtttttctc
     5041 ataatgattc tccaatcaat aaatttctat atcagtatag catgtagtaa aacaatatgc
     5101 aagcgttttc tttgatttgt gaaagaaatt cttacttttg agaagttttc cgtactattt
     5161 tatatatcag tataaatgac ggagataaaa atgtcacgta agccaagccg tgttattagg
     5221 aagatgatgt gttctcagct atttttattc agaaattgat ctctaacatt accaataaaa
     5281 aagaaaaata tcttgacaag caagggaaaa ttttgttaca ataatagacg gtacttttta
     5341 cttttggtct ctcaagagtg tacagggacg tgctgacaaa tgttgcaaaa gtacacacag
     5401 atgatatctg tcaccaagtg tatcatcacc aaaaataaaa aaacacagga gaatgtagat
     5461 gcctacaatt aaccaattgg ttcgcaaacc gcgtaaatca aaagtagaaa aatctaaatc
     5521 accagctttg aacgttggtt acaatagtca taaaaaagtt caaacaaacg tttcttcacc
     5581 acaaaaacgt ggtgttgcaa ctcgtgttgg aacaatgaca cctaaaaaac ctaactcagc
     5641 ccttcgtaaa ttcgctcgtg tacgtttgag caaccttatc gaagttactg cctacatccc
     5701 aggtatcgga cacaacttgc aagagcacag cgtggtgctt cttcgcggtg gacgtgtaaa
     5761 agaccttcca ggggtacgtt accatatcgt ccgtggtgca cttgatactg caggtgttaa
     5821 cgatcgtaaa caaggccgtt ctaaatacgg tactaaacgt ccaaaagcat aaggaaaggg
     5881 gataaagaga aatgagtcgt aaaaatagag ctccaaaacg tgacgtattg ccagatccgc
     5941 tatacaattc acaactagtt actcgtctta tcaaccgcgt tatgcttgat ggtaaacgtg
     6001 gtactgctgc ttcaatcgtt tacggtgctt ttgagcaaat caaagaagct actggcaacg
     6061 atgcacttga agtatttgaa acagctatgg aaaacatcat gcctgtactt gaagtacgtg
     6121 cacgtcgtgt tggtggttct aactaccaag tcccagttga agttcgtcca gaacgtcgta
     6181 caacacttgg acttcgttgg ttggtaacaa tcgctcgtct tcgtggtgaa cacacaatgc
     6241 aagaccgtct tgcaaaagaa atcttggatg ctgctaacaa cactggtgca gcagttaaga
     6301 aacgtgaaga tactcaccgt atggctgaag ctaaccgtgc attcgcacac ttccgttggt
     6361 aagataggat gcgaaagcgt taagaaagtc ccagagaaaa tagggaatcg aagcaggttg
     6421 cggttgcaac caatgagatt catctttttc tccagacttt tagcttgagc tcaactaaat
     6481 catgatgcta ggaacggtaa ggatgcaagg taaaaatagg aaactgacgc agtattcgac
     6541 gaatacaagg agttttatct ttttcacgca gcatcccgtt ccagctcaca tcggctaact
     6601 aactttagcc cgggttcaaa ttagctaaat cgattagtat tagctataac tcagcttacc
     6661 atctcgtaag ttgaaaccaa caatagcatg aaaacattga gaacgggtag gtcctgccta
     6721 tccgttttta ttaaaatcgt gttataatag aatagaaatc aaaaataaat aggagaaaca
     6781 aacctcatgg cacgcgaatt ttcacttgaa aaaactcgta atatcggtat catggctcac
     6841 gtcgatgccg gtaaaacaac aactactgag cgtattcttt actacactgg taaaatccac
     6901 aaaatcggtg aaactcacga aggtgcgtca caaatggact ggatggagca agagcaagaa
     6961 cgtggtatca cgatcacatc tgctgcgacg acagctcaat ggaacaacca ccgcgtaaac
     7021 atcatcgaca caccaggaca cgtggacttc acaatcgaag tacaacgttc tcttcgtgta
     7081 ttggatggtg cggttaccgt tcttgactca caatcaggtg ttgagcctca aactgaaaca
     7141 gtttggcgtc aagcaactga gtacggagtt ccacgtatcg tatttgccaa caaaatggac
     7201 aaaatcggtg ctgacttcct ttactctgta agcacacttc acgatcgtct tcaagcaaat
     7261 gcacacccaa tccaattgcc aatcggttct gaagatgact tccgtggtat cattgacttg
     7321 atcaagatga aagctgaaat ctatactaac gaccttggta cggatatcct tgaagaagac
     7381 atcccagctg aataccttga ccaagctcaa gaataccgtg aaaaattgat tgaagcagtt
     7441 gctgaaactg acgaagaatt gatgatgaaa tacctcgaag gtgaagaaat cactaacgaa
     7501 gaattgaaag ctggtatccg taaagcgact atcaacgttg aattcttccc agtattgtgt
     7561 ggttcagcct tcaaaaacaa aggtgttcaa ttgatgcttg atgcggttat cgactacctt
     7621 ccaagcccac ttgacatccc agcaatcaaa ggtattaacc cagatacaga cgctgaagaa
     7681 attcgtccag catctgacga agagccattt gcagctcttg ccttcaagat catgactgac
     7741 ccattcgtag gtcgtttgac attcttccgt gtttactcag gtgttcttca atcaggttca
     7801 tacgtattga atacttctaa aggtaaacgt gaacgtatcg gacgtatcct tcaaatgcac
     7861 gctaacagcc gtcaagaaat cgacactgtt tactcaggtg atatcgctgc tgccgttggt
     7921 ttgaaagata ctacaactgg tgactcattg acagatgaaa aagctaaaat catccttgag
     7981 tcaatcaacg ttccagaacc agttatccaa ttgatggttg agccaaaatc taaagctgac
     8041 caagacaaga tgggtatcgc ccttcaaaaa ttggctgaag aagatccaac attccgcgtt
     8101 gaaacaaacg ttgaaactgg tgaaacagtt atctcaggta tgggtgaact tcaccttgac
     8161 gtccttgttg atcgtatgcg tcgtgagttc aaagttgaag cgaacgtagg tgctcctcaa
     8221 gtatcttacc gtgaaacatt ccgcgcttct actcaagcac gtggattctt caaacgtcag
     8281 tctggtggta aaggtcaatt cggtgatgta tggattgaat ttactccaaa cgaagaaggt
     8341 aaaggattcg aattcgaaaa cgcaatcgtc ggtggtgtgg ttcctcgtga atttatccca
     8401 gcggttgaaa aaggtttggt agaatctatg gctaacggtg ttcttgcagg ttacccaatg
     8461 gttgacgtta aagctaagct ttatgatggt tcatatcacg atgtcgactc atctgaaact
     8521 gccttcaaga ttgcggcttc actttccctt aaagaagctg ctaaatcagc acaaccagct
     8581 atccttgaac caatgatgct tgtaacaatc actgttccag aagaaaacct tggtgatgtt
     8641 atgggtcacg taactgctcg tcgtggacgt gtagatggta tggaagcaca cggtaacagc
     8701 caaatcgttc gtgcttacgt tccacttgct gaaatgttcg gttacgcaac agttcttcgt
     8761 tctgcatctc aaggacgtgg tacattcatg atggtatttg accactacga agatgtacct
     8821 aagtcagtac aagaagaaat tattaagaaa aataaaggtg aagactaatc cgtcctcact
     8881 ctagaaggaa gtcacttagt ggcttccttt tgtctttaga aaatacctct aaatatggta
     8941 aaatagtaga agaataatgt gaggaaaatg aatgtcaaat agttttgaaa ttttgatgaa
     9001 tcaattgggg atgcctgctg aaatgagaca ggctcctgct ttagcacagg ccaatattga
     9061 gcgagttgtg gttcataaaa ttagtaaggt atgggagttt catttcgtat tttctaatat
     9121 tttaccgatt gaaatctttt tagaattaaa gaaaggtttg agcgaagaat tttctaagac
     9181 aggcaataaa gctgtttttg aaattaaggc tcggtctcaa gaattttcaa atcagctctt
     9241 gcagtcctac tatagggagg ctttctctga aggtccatgt gctagtcaag gttttaagtc
     9301 cctttatcaa aatttgcaag ttcgtgctga gggtaatcag ctatttattg aaggatctga
     9361 agcgattgat aaggaacatt ttaagaagaa tcatcttcct aatttagcca aacaacttga
     9421 aaagtttggt tttccaactt ttaactgtca agtcgagaag aatgatgtcc tgacccaaga
     9481 gcaggaagag gcctttcatg ctgaaaatga gcagattgtt caagctgcca atgaggaagc
     9541 gctccgtgct atggaacaac tggagcagat ggcacctcct ccagcggaag agaaaccagc
     9601 ctttgatttt caagcgaaaa aagctgcagc taaacccaag ctggataagg cggagattac
     9661 tcctatgatc gaagtgacga cagaggaaaa tcgtctggta tttgaagggg ttgtttttga
     9721 tgtggagcaa aaagtgacta gaacaggtcg tgttttaatc aactttaaaa tgacggacta
     9781 tacttcaagt ttttctatgc aaaagtgggt taaaaacgag gaagaggccc agaagtttga
     9841 cctcatcaag aagaattctt ggctccgagt tcgagggaat gtggagatga ataacttcac
     9901 acgcgatttg actatgaacg tacaggatct gcaggaagtt gttcactatg agcggaagga
     9961 tttgatgcca gaaggtgagc gtcgggttga gtttcatgct catactaaca tgtcgactat
    10021 ggatgctttg ccagaggtcg aagagattgt tgcaacagct gctaagtggg gacacaaggc
    10081 ggttgctatc acggaccatg ggaatgtcca gtcctttcca catggctata aggcggctaa
    10141 gaaagcggga atccagctga tctatgggat ggaagccaat atcgtggagg accgtgtccc
    10201 tatcgtctat aacgaagtgg agatggactt gtcagaagca acctacgtgg tctttgacgt
    10261 ggaaacgacg ggactttcag ctatctataa tgacttgatt caggttgcgg cttctaagat
    10321 gtacaagggg aatgttattg ctgaatttga tgaatttatc aatcctgggc atcccttgtc
    10381 agcctttact acagagttaa ctggaattac agatgatcat gtcaaaaatg ccaaaccact
    10441 agaacaagtt ttgcaagaat tccaagaatt ttgcaaggat acggtcctag ttgcccacaa
    10501 tgctaccttt gacgttggct ttatgaatgc taattatgag cggcatgatc ttccaaagat
    10561 tagtcagcca gttattgata cgctggagtt tgctagaaac ctctatcctg agtataaacg
    10621 ccatggtttg gggcctttga ccaagcgttt tggtgtggcc ttggaacatc accacatggc
    10681 caactacgat gcggaagcga ctggtcgtct gcttttcatc tttatcaaag aggtagcaga
    10741 aaaacatggt gtgaccgatt tagctagact caacattgat ctaatcagtc cagattctta
    10801 caaaaaagct cggatcaagc atgcgaccat ctatgtcaag aatcaggtag gtctaaaaaa
    10861 tatctttaag ctggtttcct tgtctaatac caagtatttt gaaggagtgc cacggattcc
    10921 gagaacggtt ctagatgccc atcgagaggg cttgatttta ggttcagcct gttcagaggg
    10981 tgaagttttt gacgtggtcg tttctcaagg tgtggatgcg gcggttgagg tggccaagta
    11041 ttatgatttt atcgaggtca tgccaccggc tatctatgca cccttgattg ccaaagagca
    11101 ggtcaaggat atggaggaac tccagaccat tatcaagagt ttgatagagg ttggagaccg
    11161 ccttggcaag cctgttctgg ctacgggaaa tgttcactat atcgaaccgg aagaagagat
    11221 ttatcgtgaa attatcgtcc gtagtttggg acagggtgcg atgattaatc gaactatcgg
    11281 tcatggtgaa catgcccaac cagcaccact tccaaaggct cattttcgaa cgactaatga
    11341 gatgttggat gaatttgcct ttttgggaga ggaactggct cgtaaactgg ttattgaaaa
    11401 caccaatgcc ttggcagaaa tatttgaatc cgttgaagtc gttaagggtg acttgtatac
    11461 gcctttcatc gacaaggctg aagaaacagt tgctgagttg acctataaga aagcttttga
    11521 gatttatgga aatccgctgc cagatattgt tgatttgcgg attgaaaaag aattaacatc
    11581 catactgggg aatggatttg ctgtgattta tctggcatcg cagatgctgg tgcaacgttc
    11641 taatgaacgg ggttatttgg ttggttctcg tgggtctgtc ggatctagtt tcgttgcgac
    11701 catgattggg attacggagg tcaatcctct ctctcctcac tatgtctgtg gtcagtgtca
    11761 gtacagtgag tttatcacag atggttcgta cggttcagga tttgatatgc cccataagga
    11821 ctgtccaaac tgtggtcaca aactcagtaa aaacggacag gatattccgt ttgagacctt
    11881 ccttggtttt gatggggata aggttcctga tattgacttg aacttctcgg gagaagatca
    11941 gcctagcgcc cacttggatg tgcgtgatat ctttggtgaa gaatatgcct tccgtgcggg
    12001 aacggttggt acggtagctg ccaagactgc ctatggattt gtcaagggtt acgagcgaga
    12061 ttatggcaag ttttatcgtg atgcagaagt agaacgcctc gctcaaggag cggcgggtgt
    12121 caagcggaca acaggccaac acccgggggg aatcgttgtt attccgaact acatggatgt
    12181 ctacgatttt acgcctgtcc agtatccagc agatgatgtc acggctgaat ggcagaccac
    12241 tcactttaac ttccacgata tcgatgagaa cgtcctcaaa ctcgatgtac tgggacatga
    12301 tgatccgacc atgattcgaa aacttcagga tttgtctggt attgacccta ataaaattcc
    12361 tatggatgac gaaggcgtga tggcactctt ttctgggact gatgtactag gggtaacacc
    12421 tgaacaaatt ggaacgccta cgggtatgtt ggggattcca gagtttggaa caaatttcgt
    12481 acgtggaatg gtagacgaaa cccatccgac aacctttgcg gaattgcttc agctgtctgg
    12541 tctgtcccac ggtactgacg tttggttggg gaatgctcag gatctgatta agcaaggaat
    12601 agcggaccta tcgactgtta tcggttgtcg ggacgacatc atggtttacc tcatgcatgc
    12661 gggtctggaa cctaagatgg cctttaccat tatggaacgg gtacgtaagg gtttgtggct
    12721 aaagatttca gaagaggaga gaaatggcta tatcgaagcc atgaaggcta ataaggtgcc
    12781 agagtggtat atcgaatcct gtgggaaaat taagtacatg ttccctaagg cccatgcggc
    12841 agcctacgtt atgatggcct tgcgtgtagc ttacttcaag gttcaccatc ctatttatta
    12901 ctactgtgct tacttctcca ttcgtgctaa ggcttttgat atcaagacca tgggtgcggg
    12961 cttggaggtc atcaagcgca gaatggaaga aatctctgaa aaacggaaga acaatgaagc
    13021 ctctaatgtg gaaatcgatc tctatacaac tcttgagatt gtcaatgaga tgtgggaacg
    13081 aggtttcaag tttggtaaat tagatctcta ccgtagtcag gcgacagagt tcctcatcga
    13141 cggggatacc cttatcccac catttgtagc aatggatggt ctgggagaga acgttgccaa
    13201 gcaactggtg cgggcgcgtg aagagggaga attcctctct aaaacagaac tacgcaagcg
    13261 tggtggactc tcatcaacct tggttgaaaa gatggatgag atgggtattc ttggaaatat
    13321 gccagaggat aaccagttga gtttgtttga tgagttgttt taaaaaattg cttaataatc
    13381 tattaaaaga ggctaacgta tatccaatag atttacatta gctttctttt ttgttaaaat
    13441 agtctatgga aagagggtga gagtatgtca aagatgagta taagcatccg tctggatagt
    13501 gaggttaagg agcaggccca acaggtgttt agtaatctgg gaatggatat gacaacagct
    13561 attaatattt tccttcgtca ggcaattcaa tatcagggat taccttttga tgttagacta
    13621 gacgaaaatc ggaagttgct ccaagcgtta acggatttag accaaaatcg taatatgagc
    13681 cagtcttttg aatcagtctc agatttgatg gaggacttac gtgcttaaga ttcgttatca
    13741 taaacagttt aaaaaagatt ttaagttggc tatgaagcgt ggtttgaagg cagaattatt
    13801 agaagaagtt ttgaattttc tggttcaaga aaaagaacat cctgccagat atcgtgatca
    13861 ttcattgacg gcatccaagc attttcaagg agttcgtgaa tgccataccc agccagattg
    13921 gcttttggtt tataaagtag acaagtcgga attgatttta aatttgctga ggacaggcag
    13981 tcacagtgat ttattttaat ctattttaag ggggttctca tgaaactaag aatatttgcg
    14041 gaagataagc cggctaagaa ggtatttgaa tatcaattag aacttgctga tcgtacaatt
    14101 cttctatcga cagcactctt gtcaggtgct attgctttag caggaatctt ttctgctttg
    14161 aaagaaaaat aaaaatagaa aagagaaaac agaatggttt taccaaattt taaagaaaat
    14221 ctaggaaaat atgcgaaatt gttggttgcg aacggaatta acgtgcaacc tggtcacact
    14281 ttggctctct ctattgatgt ggagcaacgt gaattggcac atctaatcgt gaaagaagct
    14341 tatgccttgg gtgcgcatga ggtcatcgtt cagtggacag atgatgtgat taaccgtgag
    14401 aaattcctcc atgccccgat ggagcgtttg gacaatgtgc cagaatacaa gattgctgag
    14461 atgaactatc ttttggagaa caaggctagc cgtcttgggg ttcgttcatc tgatccaggt
    14521 gccttgaacg gagtggacgc tgacaagctt tcagcttctg ctaaagctat gggacttgcc
    14581 atgaagccta tgcgtatcgc aactcaatct aacaaggtta gctggactgt agcagccgct
    14641 gctggacttg agtgggctaa gaaagtcttc ccaaatgctg cgagcgacga agaagcagtt
    14701 gatttccttt gggatcaaat cttcaaaact tgtcgtgtct acgaagcaga tcctgttaag
    14761 gcttgggagg aacatgcagc cattctcaag agcaaggccg atatgcttaa taaggagcaa
    14821 ttttcagccc ttcactacac agcgccagga acagatttaa cacttggttt gccaaagaac
    14881 cacgtttggg aatcagctgg tgctgtcaat gcacagggcg aagaattctt gccaaatatg
    14941 ccgacagaag aggtcttcac agcgcctgac ttccgtcgtg cagatggtta tgtcacttct
    15001 acaaaaccgc ttagctacaa cggaaatatc attgaaggca ttaaggtgac ctttaaggat
    15061 ggacaaatcg tagatatcac tgctgagaag ggtgatcagg ttatgaaaga ccttgtcttt
    15121 aaaaatgcgg gtgcgcgtgc cttgggtgaa tgtgccttgg taccagatcc aagtccaatt
    15181 tctcagtcag gcattacctt ttttaacacc cttttcgatg aaaatgcgtc aaaccacttg
    15241 gctatcggtg cagcctatgc gactagcgtt gttgatggag cggagatgag cgaagaggag
    15301 cttgaagctg cagggcttaa ccgttcagat gttcacgtag actttatgat tggttctaac
    15361 caaatggata tcgatggtat tcgtgaggat ggaacgcggg tacctctttt ccgtaatggg
    15421 aattgggcaa attaaggaga taatatgtta ggaagtatgt tcgttggtct cctagtggga
    15481 tttttagcag gtgctatgac caatcgtgga gagcgaatgg gatgttttgg aaaaatgttt
    15541 ctcggttgga tcggagcctt tctaggtcac ttgctctttg gaacttgggg gccagtttta
    15601 tcaggaacag ctattatccc agcgatttta ggagccatga ttgttttagc tattttttgg
    15661 agacgaggaa gttaatttcc taaatctgat actcaatgaa aatcaaagag caaactagga
    15721 aactagccgc aggttgctca aagcactgct ttgaggttgc agatagaact gacgaagtca
    15781 gtaacatata tacggcaagg cgacgttgac gcggtttgaa gagatttttg aagagtatga
    15841 aacgaaaagg aggttggtca ttgtactagc ctccttttga tatgatataa tagttctatg
    15901 agattagata aatttttagt tgcctgtgcg gtgggaagtc ggactgaggt caaaaacttg
    15961 ctcaaggctg ggcgcgtgac tgtaaatggt aaaaaagaaa aatcagctaa attgcagatt
    16021 gatgaaaaaa tagatgagat tcgctttgat gggcaagtgt tggagtatga agagtttgtc
    16081 tactacatga tgaacaagcc caaaggagtt atctcagcga ctgaggatcc caagcacaga
    16141 accgttctgg acttgttgga tgacttggcg cggagtaagg aagtttttcc agtaggacgc
    16201 ttggatattg acacgcatgg tcttttgctc ttgaccaata atggtcagct ggctcatgtt
    16261 cttctttcgc ccaagcgtca tgtggacaag acttatcagg ctcaggtcaa gggaattatg
    16321 acccaagaag atgtggagac atttatcaag ggcattccgc tcaaagactt tacctgtcag
    16381 cccgctagac tggagattct ttccacagat gcagaaaaga atcagagcca aatccgtgtg
    16441 accattgcag aagggaagtt tcatcagatc aagcgtatgg tgggctactg tggcaaggaa
    16501 gtggtggact tgcaacgatt gactatggga actttagtat tagatgagaa cctggaacga
    16561 ggggaatggc gtcgcttgac caaggaagaa ttagaaattc tccgcgctaa tattatttaa
    16621 tttagtttaa tactcaatga aaatcaaaga gcaaactagg aaactagccg caggctgtac
    16681 ttgagtacgg caaggcgacg ttgacgtggt ttgaagagat tttcgaagag tataaattcg
    16741 aaaaaggtga gggacaatgt cctcgccttt tatgtttttt agttgcttcc tttgtgaaaa
    16801 gagttataat agactgtaga ataaaaggag gaatctatga acgcgattca agaatcattt
    16861 actgataaac tatttgccaa ctatgaagca aatgtaaaat accaagcgat tgaaaatgct
    16921 gccagccaca acggaatttt tgcagctctg gaatgtcgcc aaagccatgt agacaacaca
    16981 cctgttttct cattggattt aaccaaggac aaggtcacta accagaaagc gtctggtcgt
    17041 tgctggatgt ttgcggctct caacaccttc cgccacaaac tcatctcgca atacaaattg
    17101 gagaactttg agttgtcaca agcccacact ttcttctggg ataagtatga gaaatcaaac
    17161 tggttcttgg agcaagtcat tgcgacttca gaccaagaat tgactagccg caaggttagc
    17221 ttcttactcc aaacacctca acaagatggc ggtcaatggg atatggtcgt ttccctcttt
    17281 gaaaaatacg gtgtcgtgcc taagtcagtt tatcctgagt ctgtttcatc tagcagcagt
    17341 cgtgagctaa atgcgatcct taataaattg cttcgtcaag atgctcaaat cttgcgtgat
    17401 ttgcttgttt ctggtgcaga tcaagcgact gttcaagcta agaaagaaga cctcttgcaa
    17461 gaaatcttta actttcttgc tatgtcatta ggacttccac cacgcaagtt tgactttgct
    17521 tatcgcgata aagataacaa ctataaaagt gaaaaaggaa tcacaccaca agagttttac
    17581 aagaaatatg tcaatcttcc tttagaagac tacgtttctg ttatcaatgc tccaactgct
    17641 gataaacctt acggaaaatc ttacacagtt gagatgttgg ggaatgtggt tggtagccgt
    17701 gcagttcgct acatcaacgt tccaatggag cgcttgaaag aattggcgat tgcccaaatg
    17761 caagcaggtg agactgtttg gtttggttct gatgtcggcc agctcagcaa ccgtaaggct
    17821 ggcatccttg cgacagatgt ttatgacttt gaatcaagca tggacattaa acttactcaa
    17881 gacaaggctg gacgtttgga ctatagcgaa agcttgatga cccacgccat ggtcttgaca
    17941 ggtgttgact tggacgaaaa tggtaaatca accaagtgga aggttgaaaa ctcatgggga
    18001 gacaaggtcg gtacagatgg ttactttgtt gcctcagacg cttggatgga cgaatacaca
    18061 taccaaatcg ttgttcgtaa ggaattgctg acagcagaag aacaagctgc ctatggagca
    18121 gaaccaatcg tacttgcacc atgggatcca atgggagcct tggctgaata aaagcataga
    18181 aaaaaggaat cagattttag aacctggttc ctttttagtt gcttgattac atgatgtgaa
    18241 gaacatgtgc cacaataccc actgcgaaga gggcaaggat aatagtgatt ggagatactt
    18301 ttttcttaag taagtacatg caaagtaaag taaggagtag tcctgataat ccaggaatca
    18361 acatatccaa gttttgttgg aaagtagtaa ctttttcagg agtttgagac aatccttgtc
    18421 ctacttgtgc gaatgcttct tggatacctt tagacccttc tggcaattta tcccaatgga
    18481 tataagcctt ttcatctagt tgaactttag aaacatcgaa agcaaattta atatttaccc
    18541 agcgttgaac aaggacagca agaatgaaca tcccaaggat agaagctcct ttagtgatat
    18601 cttgaaggat accaccagac atatctttag tgatttctga tccagccttg tatccaatct
    18661 cttgaacata ccacaagaat gacatacgaa tcaagttcca tgcaacaaag aagaggagtg
    18721 gccccaagat attgccagta agggcaagtg aagcaccgag agatccaagg attgggcgta
    18781 ctgtaaacca gaatactggg tcaccgatac cagcaagagg tcccatcata ccgattttaa
    18841 ccccttggat agcagcgtca tcgatttcca caccgttagc acgttcttct tcaagcgcaa
    18901 gagtaacccc catgactgga gcagctacgt atggatgagt gttgaagaac tcaaggtgac
    18961 gctcaagagc agcgatttga tcttcttttt tagtatagag ttttttgata gctggaatga
    19021 gtgtataagc ccagcccaag ttttgcatcc gttcaaagtt ccaagaccct tgtaagaagg
    19081 ttgaacgcca ccaaactttt ttacgatctg atttagttaa ttgaagtttt tcagtcatga
    19141 tgttttcagt cctttcttat cttagtagtc ttctaggata tcgccgattg ggtcgttaga
    19201 agttgcggct cctccgccac catttccacc agttttagaa aggtgaaggt agataagagc
    19261 gatagcaaca ccgatagcac cgaatccgat tagagtaata tctgacacag cagcaagaac
    19321 gaaaccaaga gcgaagaatg gccatacttc acgagttgcc atcatgttga taaccatggc
    19381 gtaaccaacg gcaacgacca taccaccacc gatagccata ccatctttga gccagtctgg
    19441 catggcacta aggatacttt gtacagtttc agttggtacc ataaggagaa gagctgcagg
    19501 aagcgcgata cgaagtcctt ggaaaagtag cgcaatgaaa tgagcacgct ccacagcgcc
    19561 gaagtcacct tttttagcgg cagcatcagc agtgtgaacc aatccaactg aaattgtacg
    19621 aacaatcata gttaagaata gaccagctac ggcaagaggg atagcaaccg cttgggcaac
    19681 accgatacca gtcttggtaa agtcaccacc aagaaccatg ataatggcag cagcgacaga
    19741 agcaagtgca gcatcaggag cgatagcagc accgatattt gaccaaccaa gggcaatcat
    19801 ttgaagcgat ccaccgagga taatccctgc ttccaagtga cctgttacaa gcccaataag
    19861 ggtacaggct acaagtggtt ggtgaaattg gaactggtcg aggatgcctt caagacctgc
    19921 aaagaaggct acaacgacta ctaaaaccat agaaataata gacatgttta aaatcctttc
    19981 ataaataatg gcttatttga cattggcttt gttaatcaag tcaaacaaat cttttttaga
    20041 atcatttggt actttacgga catcaaattc aacacccaag tcacgcattt tttcaaatgt
    20101 agcaacatct tctttgtcca tagacaaaac ggtattgacc aatgttttac ctgttgagtg
    20161 agccatagaa ccaacgttaa gagtcttgat tggcacgccg ccttcgatgg cacgaagggc
    20221 atcttgaggt gtttcaaaca agataagggc atgtgtttct ccaaaacgtg ggtcttttga
    20281 aatctcaatc agtttttgaa ttggaaccac gttagccttg acattacctg gagctgcttg
    20341 tttaatcaat tctttacgaa ggtcgtcttt agccacgtta tctgaagcaa cgatgatacg
    20401 atttgctttt gaatctggag tccaagcagt tgcaacctga ccgtgaagta gacgtgtgtc
    20461 aagacgggca agattgattt tcaatttacc gtctccgata acagttcctt ctgggatagc
    20521 agtttgggca actggagcag ctgcagcgct tgcaacttct tcaactggat ttagctcttc
    20581 tggaagagct ttgatgccat ctttggcttc tttaatgata ttagcagcga ctttttctac
    20641 acctgcagca gcgtccatga ggcgctctgt gtaggcttga atcaacatcg gtaagttaag
    20701 tcctgtgatg atggcaaact tacgctcagg attttctccc atcacgcgac tagcttggtt
    20761 aaatggagaa ccactccaaa ggtcagccaa aactagaacc tcatcttctg cgtcaaatgc
    20821 agcaacagcg ttattaaact tagcgtatag atcatcagga ccttcatttg gcataaaggt
    20881 cacaacttga accttttctt gttcaccaaa gatcatagat cctgactgat gaatacccgc
    20941 agcaaattcg ccgtggctcg caataatgat tccgatactc attattgtca ttcctccttt
    21001 tttgttttag ttttcattta agaaaacttt aagactgttt aagtataaac cgttttcata
    21061 aaaaaagcaa ctatttatca taaaaaatta aaaaattttt atttttgtat gttgatatgt
    21121 tgagtttttg aggagtaatc ttgaattctt atttaaaatt taatataaaa aagttggaag
    21181 aagcttccaa cttttaaaat aggtttctat taaattagtg ggtgaagtcg agtaccatac
    21241 gtccttggat ttggcctttt tccatttcgt cgaaaatggc aacagcatct tctactggac
    21301 gtttttgaac aactgggact accagacctt ctgcaccaaa ttggaaggct tcttctaagt
    21361 ctttacgagt tccgacaaga gaaccgatga cttggattcc atcgaggact gttttaacga
    21421 tgctgagttc catcatttca gaaggaagac caacagcgac gacgcgacca ccagcacgaa
    21481 tggagtcaac agcctggttg aaggcaactt tagacacagc agttacgaca gctgaatgag
    21541 ctcctccatc agttttttct ttaatgagtc cagctacatc ttcaacttcg aggccgttaa
    21601 tcacaatgtc agcgcctact tcttttgcaa gggtaagttt gtcattgttg atatcgactg
    21661 cgataacatg agcattgaat acttttttag cgtattgaac agcgaggtta ccaagtccac
    21721 cagcaccgta aagaacaacc cattggcctg gttcaacttt tgcttctttg atagctttat
    21781 aggttgttac tccagcacat gtgatagaag aagcttgggc tggatcaagt ccgtcaggaa
    21841 ctttgacagc atagtcagca gttacgatac attgttcagc cataccaccg tctactgagt
    21901 agccagcatt tttcactgta cggcaaaggg tttcgcgacc agttgtacag tattcgcaag
    21961 tgccacatcc ttcaaagaac caagcaacgc tgacgcggtc accgacttta aggcttttca
    22021 catctggagc aatctcttta acgataccga taccttcgtg cccaagaaca cgtcctggga
    22081 cttgaccaaa gtcaccatga gcaacgtgga ggtcggtgtg gcaaacgcca cagtattcaa
    22141 cttctacaag tgcttcccca gtttcaagtg gacggagtac tttttcttca atagcaacac
    22201 cagtgctttc tggatttaca acaacagctt tcatagctat cctccttgat attgaccgag
    22261 aacagggaca acgggactgg attgattttt tgtcaacaga gtcgagtgtg acgagctctc
    22321 ttgtatttat atgtgaagta tatcacaaaa ggaagccttt tccaaggttt tggagacaaa
    22381 aagtagaaca atcgattaac tggttgatga gactgtgaaa agagcacaaa gaccagcttg
    22441 caagctggtc atactcttcg aaaatctctt caaaccacgt cagcttcatc tacaacctca
    22501 aagcagtgct ttgagcaacc tacggctagc ttcctagttt gctctttgat tctcattgag
    22561 tatcagtata ggttataaga ataagtcttg tagggttttg gcaaccccat cttggtcgtt
    22621 ggtaagggaa atttgctcat ctgcataagg gagtagctct ggattggcat ttttcatggc
    22681 ataacccttc ccagcaaaag cgagcatttc ggtatcattg tgttcatctc caaaggcaat
    22741 caaatctttt ttgtcacgat tcattatctt gagcaagtag tccaaagcaa aggccttgtt
    22801 gacacctttt ggggtacatt caaggatatt gagcggacct ccccaggtat tgatagaaag
    22861 ttgatgctgg tagaaggcgt tcatttcttt tgccaaggca tatttgtcac tggctctggt
    22921 ctgcaagagg atacagttag ggtccttggt caccaattca ggctggaatt gatcttcagg
    22981 ctggaaagct tctacaccaa atagtttggg attggcaatt tcttcattgg gatttgtaat
    23041 gtagaatttt ttacgatatt ctccagcgat aaaatcggct tgaatgtcct ctgaacgttg
    23101 aaccatatct agcagatatt ttttgtctac agtcaaacac ttttcaaaat cccaaacttg
    23161 gtctggtaaa tgagtaaggg atccgttgaa gttaatcata ggagtgtcta agcccagttc
    23221 acggtaaaaa tcttttgaca tacggtaagg gcgacctgtc gtaataataa cctgatggcc
    23281 tttttcagca acttttttga tggttctttt ggtaaagtca gaaatttgac tgtctgagtt
    23341 gagcagggtt ccatccaggt caactgcaat aatttttttc gtcatatgga cctttctagt
    23401 gtgttttcag ataagatgtc ttctattata acagaaagca ggcagaaaag cagattccaa
    23461 acaaaaaatg aaattggatt aatttcttaa acaaatcaaa caaagacatt gaaaaagtga
    23521 atgataaatg atataattct attattgttc gtaaaaatta aaaggagatt gatgatggac
    23581 aaattattta aactaaaaga gaacggtaca gacgttcgta cagaggttct cgctggttta
    23641 acaactttct ttgcaatgag ctatattctc tttgtaaacc cacaaatact ttcacaaaca
    23701 ggaatgcctg ctcagggcgt cttcctagcg acgattattg gtgcagtagc gggtaccttg
    23761 atgatggctt tttatgctaa cttaccttat gcccaagcac caggtatggg actcaatgcc
    23821 ttctttacct ttacagttgt attcgggctt ggttattctt ggcaagaagc cctagctatg
    23881 gtcttcatct gtgggattat ttcattgatt attaccttga caaatgttcg taaaatgatc
    23941 attgaatcga ttcccaatgc tcttcgctca gctatttcag ctggtatcgg tgtcttcctt
    24001 gcctatgtag ggattaagaa tgctggactt ttgaaattca cgattgatcc aggcaactat
    24061 actgttgtag gagaaggggc tgacaaagct caagcaacga ttgcagcaaa ctcttcagca
    24121 gttccaggat tggtcagctt taataatcca gctgttttag tggctcttgc aggacttgcc
    24181 attactatct tctttgtcat caaagggatt aaagggggaa ttattctctc tatcttgaca
    24241 acaactgttc ttgctattgc agttggtttg gttgatttgt ctagtatcga ttttgctaat
    24301 aaccatgttg gtgcagcttt tgaagatttg aagacaatct ttggtgcagc tcttggttca
    24361 gaaggtttgg gagctttggt ttcagataca gctcgcttgc ctgaaactct gatggccatt
    24421 cttgccttct cattgacaga tatttttgac acaattggta ccttgatcgg tacaggtgaa
    24481 aaagttggta ttgtagcgac aaatggtgaa aatcaccaat cagccaaatt ggataaggct
    24541 ctttactctg atttgattgg aacgacagtc ggtgccattg caggtacttc aaacgtaacg
    24601 acttatgttg agtctgctgc tggtatcggt gcaggtggac gtactggttt gacagccttg
    24661 gttgtagcta tctgttttgc gatttcaagc ttctttagcc cacttctagc gatcgtacca
    24721 acagcggcta cagctccaat cttgattatc gttgggatta tgatgcttgg tagcttgaaa
    24781 aatatccatt gggatgatat gtctgaagca gttcctgcct tcttcacatc tatctttatg
    24841 ggattcagct actctatcac tcaagggatt gcagttggtt tcttgactta cactttgact
    24901 aagcttgtca aaggtcaagt taaagatgtt catgccatga tttggatttt ggatgccttg
    24961 tttatcctta actacatcag catggcctta taatagaatg acccaggggg atttcccccc
    25021 ttttttaata caaaggagat aggtgatgaa agagaaaaat atgtggaaag aattgttgaa
    25081 tcgtgcaggc tggattttgg tctttttact tgccgtcctt ttatatcagg ttcccctagt
    25141 ggttacctct attttgactt taaaagaagt agccctgcta cagtcagggc tgatagttac
    25201 tggcctttca attgtggttc tggctctatt tattatggga gctcgtaaaa ccaagttagc
    25261 tagttttaat ttttcttttt ttagagctaa agatttggca cgtttgggct tgagttattt
    25321 agttattgtc gggtcaaata tacttggttc tatcttgttg caactgtcaa atgagacgac
    25381 aacagctaac cagtctcaga ttaacgatat ggttcagaat agttctctga tttctagctt
    25441 cttcttgcta gccttgcttg ctccaatttg tgaggaaatc ttgtgccgtg ggattgttcc
    25501 taaaaagatt ttccgaggca aggagaactt gggatttgta gtcggtacga ttgtgtttgc
    25561 tttattgcat caaccaagta atttaccttc tttattgatt tatggaggta tgtcgacagt
    25621 tctatcttgg acggcctaca agacccaacg tttggaaatg tcgatcttgc ttcacatgat
    25681 tgttaatggg attgctttct gtttgttggc tcttgtggtg attatgagtc ggacattagg
    25741 aatttctgtg taaaagtttt tatgtaggaa ccgacctctt tctactaggg aaagatgaat
    25801 gcaatcgtgt ccatcttttt ctttttatgg taaaatagaa aaataatatg atgaaaatcc
    25861 ttgagggagt gaccgatatg tcaagtaaag ccaatcatgc aaagacagtt atttgcggaa
    25921 ttatcaatgt aaccccagac tccttttcgg acggtggtca attttttgct cttgagcagg
    25981 cactccagca ggctcgtaaa ttgatagcag aaggagccag tatgctcgat atcggcggag
    26041 aatcgactcg gccgggcagt agctatgttg agatagaaga ggaaatccag cgtgttgttc
    26101 cagtgatcaa agcgattcgc aaggaaagtg atgtccttat ttctatcgat acttggaaaa
    26161 gtcaggtggc agaggctgct ttggctgctg gtgccaatct agttaatgat atcactggtc
    26221 tcatgggcga tgaaaaaatg gcccatgtgg ttgctaaagc tggagcgaaa gtagtcatca
    26281 tgtttaatcc agtcatggct cgacctcaac atcctagttc gcttatcttc cctcattttg
    26341 gctttggtca aacctttaca gaaaaagagt tagctgactt tgaaacattg ccaatcgaag
    26401 acttgatggt ggctttcttt gaacgagcac tagcgagagc ggcagaagct ggtattacac
    26461 cagaaaatat cctgttggat ccaggaattg gctttggtct gaccaagaaa gaaaatctcc
    26521 tccttttacg ggacctggat aaactacatc agaagggcta tccaatcttt ctcggagtgt
    26581 cgcgcaagcg atttgtcatc aatatccttg aagaaagtgg gtttgaagtc aatcctgaga
    26641 cagagcttgg tttccgaaat cgggacacgg cttcggctca tgtaactagt atcgctgcga
    26701 gacagggtgt agaagtggtg cgcgtgcatg acgtagctag tcacaggatg gcagttgaaa
    26761 ttgcctctgc cattcgtctg gctgatgaag cggaaaattt agatttaaaa caatataaat
    26821 aagatgaaag aaattgaaaa caatcagtgg attgctaact accggacgga tcaaccgcat
    26881 tttggattgg aacgaatggt ggaactgtta gctttgcgtg gcaatcccca tctcaaactc
    26941 aaggtcctcc atatcggagg gactaacggc aagggctcga ctattgcttt tttgaaaaag
    27001 atgctagaaa agctagggct gagagttggc gtgtttagct cgccctatct cattcattac
    27061 acagaccaga ttagcatcaa tggggaatcg atctcagaag cgaggctaga agctctcatg
    27121 gcagactatc agtctttgct ggagggagaa gcggtcgcca atttacaggg cacaaccgag
    27181 tttgagatta tcacagccct ggcctatgac tactttgcct cagagcaagt agatgtggcc
    27241 atcatggaag ttggcatggg tggacttttg gatagtacca atgtctgtca gcccattttg
    27301 acaggaatta caactattgg cttggatcat gtggccctac ttggtgacac cttggaggcc
    27361 atagcagagc agaaggcagg tattatcaaa caagggatac ccttggtaac agggcgtatt
    27421 gctccagaag ccttgactgt gattgaccgc attgcggaag ggaaagatgc gccgagactt
    27481 gcctacggga cagattatca ggttcgtcat caagaaagtg tggtgacagg ggaagtcttt
    27541 gactatacaa gtgctgtcag acaaggtcgc ttccagacta gcctgcttgg tttgtaccaa
    27601 atagagaatg ctgggatggc catagcttta cttgatactt tttgtcaaga agatggtcga
    27661 gagctagcaa gcaatgactt tcttggtcaa gccttggaag aaacaagttg gccagggcgt
    27721 ttggaaatcg tgtcaagaga tcccttgatg attttggatg gagcccataa tccccatgct
    27781 atcaaggcct tgttggtaac cttgcaagaa cgttttgcgg attatcataa ggaaatcctc
    27841 ttcacttgta tcaaaaccaa agccttggag gatatgttgg acttgctggg agccatgcca
    27901 gataccgagc ttactctaac acattttgcg gatagtcggg cgacggatga aagcgtgctg
    27961 aaagaggcag ctaagtctag aaatctcagc taccaagatt ggcatgattt tctagagcag
    28021 aatttgacag ataaaaaaga agagaaacaa acagttagga ttgtcacagg ttccttgtat
    28081 ttcttgagcc aagtgagggc ctatctgatg gagaggaaga acgagaatgg atacacaaaa
    28141 gattgaagca gctgtaaaaa tgattatcga ggctgtagga gagaacgcta atcgcgaggg
    28201 cttgcaggaa acacctgctc gtgtagcccg tatgtatcaa gagatttttt caggtcttgg
    28261 tcaaacagca gaggaacatt tgtcaaaatc ctttgaaatt attgacgata atatggtggt
    28321 agaaaaggat atctttttcc ataccatgtg tgaacaccac ttcttgccat tttatggtag
    28381 agcgcacatt gcctacattc cagatggtcg tgtggcaggc ttgtctaagc tagcccgtac
    28441 ggttgaagtt tattcgaaaa aaccacaaat tcaagaacgt ttgaatatcg aagtggccga
    28501 tgccttgatg gactatctag gtgctaaagg agcctttgtt gtcattgagg cggaacatat
    28561 gtgtatgagt atgcgtggtg ttagaaaacc aggcactgca accttgacga cagtagctcg
    28621 tggtctattt gaaacagata aggacctccg cgaccaagct tatcgtttaa tggggctata
    28681 aaaagaatcc gcttcaagcg gatttttcta gaaaggaatc attatggatc aactgcagat
    28741 taaggatttg gaaatgtttg cctatcatgg tctttttcct agtgagaaag aattggggca
    28801 gaaatttgtc gtttcagcca tcctatccta tgatatgacc aaggcagcta cagacttgga
    28861 tttaacagcc tctgtccatt acggagaatt atgtcagcag tggacgactt ggtttcagga
    28921 aacgagtgaa gatttgattg aaacggtagc ctataaactg gtggaacgta cctttgagtt
    28981 ttatcctctt gtccaagaaa tgaagttgga actgaaaaaa ccttgggcac cggtgcattt
    29041 gtcactagat acttgctcgg taaccattca tcgccgcaag caacgagcct ttatcgccct
    29101 aggaagcaat atgggagata aacaagcaaa cttgaagcaa gccattgaca aactgcgagc
    29161 tcgtggcatc tatattctca aagagtccag tgtcttagcg acggagcctt ggggtggagt
    29221 ggagcaggat agctttgcca atcaagtggt tgaggtggaa acctggctac cagcacaaga
    29281 cttgttagaa accttgttag ccattgagtc agagctggga cgggtgagag aagtgcattg
    29341 gggacctcgt ttgattgatt tggacttgct ctttgtggag gaccagatcc tttatacaga
    29401 cgacctcata ttgcctcatc cttacatagc ggaacgcctt tttgtccttg agtccttaca
    29461 ggaaattgcg cctcatttta tccatccgac attaaaacaa ccgatccgca acttgtatga
    29521 tgctttgaaa aaatagaaaa actctagttt tcagttactt gcaactgaag gctagagttt
    29581 ttaaaatagg tcattttctt ctgggaggag gatagtttct ctaccgtaca tgtctaaaac
    29641 cagtactctt gggggataac gagggtcgaa aggatggtta aagtcaaaat caatggctgt
    29701 agggaggtgt tgacttgaaa agtggaaggt aatctttcct tggttattaa gcaattgaaa
    29761 ctcgagttct tcttccaatt caaagacatt ttttaagaaa tgatcgatga tataccaaaa
    29821 agagtcaatg atgtcatcgg gcaagctggt aacaatgcca aaactagcag accgcatgtg
    29881 ggtattggta aaagccatat ctctgtcccc tttcttttcc cttatcatac agcaaatagg
    29941 attaaaaatc aagaaaaggt gattttttga aaaggatttt aactacaggg aaaaataagg
    30001 aaaaaaattc ccaaaaatct accgaagtta ataggtaaat tcccaaatta acttgattat
    30061 ataactttca gtt
//
LOCUS       DAVBBO010000023        29758 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ST1
            SAMEA2066453-rid20184263.denovo.023, whole genome shotgun sequence.
ACCESSION   DAVBBO010000023 DAVBBO010000000
VERSION     DAVBBO010000023.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2066453
            Sequence Read Archive: ERR351777
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 29758)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 29758)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980402.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980402.1
            Genome Coverage       :: 176x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:17:33
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,141
            CDSs (total)                      :: 2,104
            Genes (coding)                    :: 1,953
            CDSs (with protein)               :: 1,953
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 16S)
            partial rRNAs                     :: 1 (23S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 151
            CDSs (without protein)            :: 151
            Pseudo Genes (ambiguous residues) :: 0 of 151
            Pseudo Genes (frameshifted)       :: 73 of 151
            Pseudo Genes (incomplete)         :: 76 of 151
            Pseudo Genes (internal stop)      :: 40 of 151
            Pseudo Genes (multiple problems)  :: 32 of 151
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..29758
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2066453-rid20184263.denovo.023"
                     /strain="ST1"
                     /db_xref="taxon:1313"
     gene            132..494
                     /locus_tag="VQU30_001013"
     CDS             132..494
                     /locus_tag="VQU30_001013"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001234364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2447138.1"
                     /translation="MRLASESRQILDKLKDDVYNKLGYEVSYSSIVSQAVREYVPKKE
                     RIDWIKLKETAIPFSSLKQSNNWEYQTSLMLEKDVLILLSELQNFFLDVFQAKRIHRA
                     FCIRLCLRAQFLLSNNDS"
     gene            902..1201
                     /locus_tag="VQU30_001014"
     CDS             902..1201
                     /locus_tag="VQU30_001014"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001081475.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2447139.1"
                     /translation="MNRNVLNFLRTESAERVSLYIDKANRLEGDVTLLAPSSQDLEDI
                     KNAMFSNPNLELKVARLDVMKKIAYASTRNHYLTGATIFGDISKGTYNCDPKSYV"
     gene            complement(1296..1733)
                     /locus_tag="VQU30_001015"
     CDS             complement(1296..1733)
                     /locus_tag="VQU30_001015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000737922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2447140.1"
                     /translation="MKKLYRIHFIAIAVIDLLLFAFFITRLETSFEWLLLSGLIFFLA
                     QGLLLFLLVVRLKHQFAEIYPQINKKIRFYYLGVLTIDFLFFVLLAFISSQRFSSLMP
                     IITACHSTFYYMTADYLRENYPDFYDKHISNTYTILSISSFLV"
     gene            complement(1864..2498)
                     /locus_tag="VQU30_001016"
                     /pseudo
     CDS             complement(1864..2498)
                     /locus_tag="VQU30_001016"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001819460.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinamide mononucleotide transporter"
     gene            complement(2709..3359)
                     /locus_tag="VQU30_001017"
     CDS             complement(2709..3359)
                     /locus_tag="VQU30_001017"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000188500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-dependent transcriptional regulator"
                     /protein_id="HET2447141.1"
                     /translation="MTPNKEDYLKCIYEIGIDLHKITNKEIAARMQVSPPAVTEMIKR
                     MKSENLILKDKECGYLLTDLGLKLVSELYRKHRLIEVFLVHHLDYTSDQIHEEAEVLE
                     HTVSDLFVERLDKLLGFPKTCPHGGTIPAKGELLVEINNLPLADIKEAGAYRLTRMHD
                     SFDILHYLDKHSLHIGDQLQVKQFDGFSNTFTILSNDEDLQVNMDIAKQLYVEKIN"
     gene            3471..4313
                     /locus_tag="VQU30_001018"
     CDS             3471..4313
                     /locus_tag="VQU30_001018"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862319.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase family protein"
                     /protein_id="HET2447142.1"
                     /translation="MTKIALLSDIHGNTTALEAVLADARQLGVDEYWLLGDILMPGTG
                     RRRILDLLDQLPITARVLGNWEDSLWHGVRKELDSTRPSQRYLLRQCQYVLEEISLEE
                     IEVLHNQPLQIHRQFGDLTVGISHHLPDKNWGRELIHTGKQEEFDRLVTHPPCDIAVY
                     GHIHQQLLRYGTGGQLIVNPGSIGQPFFLDAQLRKDLRAQYMILEFDDKGLVDMDFRR
                     VDYDVAAELQLAKDLRLPYFEVYYESLVNGIHHTHHQEFLRELAQKEGCDRELDDWLK
                     SGND"
     gene            4389..4826
                     /locus_tag="VQU30_001019"
     CDS             4389..4826
                     /locus_tag="VQU30_001019"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004263219.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rrf2 family transcriptional regulator"
                     /protein_id="HET2447143.1"
                     /translation="MQIPSRFTIATHMLIIIALEGKKSKVTSDFLAASVGVNPVIIRK
                     ILSQLKKAELISVARGTGGTDIVKDLKDISLLDVYQAVECLGKTGQLFSFHDNPNPNC
                     PVGAHIHDVLDQKLERIQLTMEAELGQTSLEKVVADAESQMKD"
     gene            4894..5196
                     /locus_tag="VQU30_001020"
     CDS             4894..5196
                     /locus_tag="VQU30_001020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000281600.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2447144.1"
                     /translation="MYLVIGIVLAFIVSFWKDNRSLWNPVLFLLSLISSYFYLSYLFY
                     KNGYENVQLAFYVFAFVLLPFLLFLSGIFLIYNGVILLKREGRSKPHYLSMLFDFY"
     gene            complement(5287..6360)
                     /locus_tag="VQU30_001021"
     CDS             complement(5287..6360)
                     /locus_tag="VQU30_001021"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001273827.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2974 domain-containing protein"
                     /protein_id="HET2447145.1"
                     /translation="MANIFDYLKDVAYDSYYDLPLNELDILTLIEITYLSFDNLVSTL
                     PQRLLDLAPQVPREPTMLTSKNRLQLLDKLAQHKRFKNCKLSHFINDIDPELQKQFAA
                     MTYRVSLDTYLIVFRGTDDSIIGWKEDFHLTYMKEIPAQKHALRYLKNFFAHHPKQKV
                     ILAGHSKGGNLAIYAASQIEQSLQNQITAVYTFDAPGLHQELTQTAGYQRIMDRSKIF
                     IPQGSIIGMMLEIPAHKIIVQSTALGGIAQHDTFSWQIEDKHFVQLDKTNSDSQQVDT
                     TFKEWVATVPDEELQLYFDLFFGTILEAGISSINDLASLKALEYIHHLFVQAQSLTPE
                     ERETLGRLTQLLIDTRYQAWKNR"
     gene            6516..7193
                     /locus_tag="VQU30_001022"
     CDS             6516..7193
                     /locus_tag="VQU30_001022"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000548969.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HET2447146.1"
                     /translation="MHKILLIEDDQVIRQQIGKMLSEWGFEVVLVEDFMEVLSLFVQS
                     EPHLVLMDIGLPLFNGYHWCQEIRKISKVPIMFLSSRDQAMDIVMAINMGADDFVTKP
                     FDQQVLLAKVQGLLRRSYEFGRDESLLEYAGVILNTKSMDLHYQGQVLNLTKNEFQIL
                     RVLFEHAGNIVARDDLMRELWNSDFFIDDNTLSVNVARLRKKLEEQGLVGFIETKKGI
                     GYGLKHA"
     gene            7186..8160
                     /locus_tag="VQU30_001023"
     CDS             7186..8160
                     /locus_tag="VQU30_001023"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HET2447147.1"
                     /translation="MLDWKQFFLAYLRSRSRLFIYLLSLAFLVLLFQFLFASLGIYFL
                     YFFFLCCFVTILFFTWDILVEMQVYRQELLYGEREAKSPLEIALAEKLEAREMELYQQ
                     RSKAERKLTDLLDYYTLWVHQIKTPIAASQLLVAEVVDRQLKQQLEQEIFKIDSYTNL
                     VLQYLRLESFHDDLLLKQVQIEDLVKEIIRKYALFFIQKGLNVNLHDLDKEIVTDKKW
                     LLVVIEQIISNSLKYTKEGGLEIYMDDQEICIKDTGIGIKNSDVLRVFERGFSGYNGR
                     LTQQSSGLGLYLSKKISEELGHQIRIESEVGKGTTVRIQFAQVNLVLE"
     gene            complement(8209..10152)
                     /gene="thrS"
                     /locus_tag="VQU30_001024"
     CDS             complement(8209..10152)
                     /gene="thrS"
                     /locus_tag="VQU30_001024"
                     /EC_number="6.1.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000608363.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine--tRNA ligase"
                     /protein_id="HET2447148.1"
                     /translation="MINITFPDGAIREFESGVTTFEIAQSISNSLAKKALAGKFNGKL
                     IDTTRAITEDGSIEIVTPDHGDALPILRHSAAHLFAQAARRLFPDIHLGVGPAIEDGF
                     YYDTDNTAGQISNEDLPRIEEEMQKIVKENFPSIREEVTKDEAREIFKNDPYKLELIE
                     EHSEDEGGLTIYRQGEYVDLCRGPHVPSTGRIQIFHLLHVAGAYWRGNSDNAMMQRIY
                     GTAWFDKKDLKNYLQMREEAKERDHRKLGKELDLFMISQEVGQGLPFWLPNGATIRRE
                     LERYIVNKELASGYQHVYTPPLASVELYKTSGHWDHYQEDMFPTMDMGDGEEFVLRPM
                     NCPHHIQVFKHHVHSYRELPIRIAEIGMMHRYEKSGALTGLQRVREMSLNDGHLFVTP
                     EQIQEEFQRALQLIIDVYEDFNLTDYRFRLSLRDPQDTHKYFDNDEMWENAQTMLRAA
                     LDEMGVDYFEAEGEAAFYGPKLDIQIKTALGKEETLSTIQLDFLLPERFDLKYIGADG
                     EDHRPVMIHRGVISTMERFTAILIENYKGAFPTWLAPHQVTLIPVSNEKHVDYAWEVA
                     KKLRDRGVRADVDERNEKMQFKIRASQTSKIPYQLIVGDKEMEDETVNVRRYGQKETQ
                     TVSVDNFVQAILADIANKSRVEK"
     gene            complement(10210..10386)
                     /locus_tag="VQU30_001025"
                     /pseudo
     CDS             complement(10210..10386)
                     /locus_tag="VQU30_001025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000166032.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="MazG-like protein"
     gene            complement(10393..10533)
                     /locus_tag="VQU30_001026"
     CDS             complement(10393..10533)
                     /locus_tag="VQU30_001026"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000422774.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MazG-like protein"
                     /protein_id="HET2447149.1"
                     /translation="MELQELVERSWAIRQAYHELEVKHHDFKWTVEEDLLALSNDIGN
                     FQ"
     gene            complement(10964..11164)
                     /locus_tag="VQU30_001027"
     CDS             complement(10964..11164)
                     /locus_tag="VQU30_001027"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001826938.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2447150.1"
                     /translation="MRRFYSHLPYYLVILFFYWPLYELFLLVVSDPLTLKGLYINNLL
                     FFTPMVILIVSLLYSYRFRFSL"
     gene            11403..11948
                     /locus_tag="VQU30_001028"
     CDS             11403..11948
                     /locus_tag="VQU30_001028"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001852743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)-dependent oxidoreductase"
                     /protein_id="HET2447151.1"
                     /translation="MKLAVIAANGQAGKAIVEEAVKRGHEVTAIVRSENKSQAESIIK
                     KDLFELTKDDLTGFDAVISAFGAYTPDTLPLHSKSIELFNQLLAGTQTRFLVVGGSGS
                     LYIDETKTTRLLDTPDFPEEFKSLAKAQADELDLLRTKNNLNWAFVSPAVDFIPDGEK
                     TGNYILAGEIFTTNEKRNKPD"
     gene            12174..12443
                     /gene="rpsO"
                     /locus_tag="VQU30_001029"
     CDS             12174..12443
                     /gene="rpsO"
                     /locus_tag="VQU30_001029"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001018251.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S15"
                     /protein_id="HET2447152.1"
                     /translation="MAISKEKKNEIIAQYARHEGDTGSVEVQVAVLTWEINHLNEHIK
                     QHKKDHATYRGLMKKIGRRRNLLAYLRKNDVNRYRELINSLGLRR"
     gene            13259..13873
                     /locus_tag="VQU30_001030"
     CDS             13259..13873
                     /locus_tag="VQU30_001030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000531723.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CadD family cadmium resistance transporter"
                     /protein_id="HET2447153.1"
                     /translation="MGQTIISAIGVYISTSIDYLIILIILFAQLSQNKQKWHIYAGQY
                     LGTGLLVGASLVAAYVVNFVPEEWMVGLLGLIPIYLGIRFAIVGEDAEEEEEEIIERL
                     EQSKANQLFWTVTLLTIASGGDNLGIYIPYFASLDWSQTLVALLVFVIGIIIFCEISR
                     VLSSIPLIFETIEKYERIIVPLVFILLGLYIMYENGTIETFLIV"
     gene            complement(14165..14914)
                     /locus_tag="VQU30_001031"
     CDS             complement(14165..14914)
                     /locus_tag="VQU30_001031"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000500208.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-acyl-sn-glycerol-3-phosphate acyltransferase"
                     /protein_id="HET2447154.1"
                     /translation="MFYTYLRGLVVLLLWSINGNAHYHNTDKIPNQDENYILVAPHRT
                     WWDPVYMAFATKPKQFIFMAKKELFTNRIFGWWIRMCGAFPIDRENPSASAIKYPINV
                     LKKSDRSLIMFPSGSRHSNDVKGGAALIAKMAKVRIMPVTYTGPMTLKGLISRERVDM
                     NFGNPIDISDIKKMNDEGIETVANRIQTEFQRLDEETKQWHNDKKPNPLWWFIRIPAL
                     ILAIILAILTIIFSFIASFIWNPDKKREELA"
     gene            15047..17383
                     /locus_tag="VQU30_001032"
     CDS             15047..17383
                     /locus_tag="VQU30_001032"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000360031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD-IC family P-type ATPase"
                     /protein_id="HET2447155.1"
                     /translation="MDKNKIMGLTQREIKERQAEGLVNDFTASASTSTWQIVKRNVFT
                     LFNALNFAIALALAFVQAWSNLVFFAVICFNAFSGIVTELRAKHMVDKLNLMTKEKVK
                     TIRDGQEVALNPEELVLGDVIRLSAGEQIPSDALVLEGFAEVNEAMLTGESDLVQKEV
                     DGLLLSGSFLASGSVLSQVHHVGADNYAAKLMLEAKTVKPINSRIMKSLDKLAGFTGK
                     IIIPFGLALLLEALLLKGLPLKSSVVNSSTALLGMLPKGIALLTITSLLTAVIKLGLK
                     KVLVQEMYSVETLARVDMLCLDKTGTITQGKMQVEAVLPLTETYGEEAVASILTSYMA
                     HSEDKNPTAQAIRQRFQGQVVYPMLSNLPFSSDRKWGAMELEGLGIVFLGAPEMLLDS
                     EVPEAREALERGSRVLVLALSQEKLDHHKPQKPSDIQALALLEILDPIREGAAETLNY
                     LRSQEVGLKIISGDNPVTVSSIAQKAGFADYHSYVDCSKITDEELIALAEETAIFGRV
                     SPHQKKLIIQTLKKAGHTTAMTGDGVNDILALREADCSIVMAEGDPATRQIANLVLLN
                     SDFNDVPEILFEGRRVVNNIAHIAPIFLIKTIYSFLLAVICIASALLGRSEWILIFPF
                     IPIQITMIDQFVEGFPPFVLTFERNIKPVEPNFLRKSMLRALPSALMVVFSVLFVKIF
                     GTSQGWSELEISTLLYYLLGSIGFLSVFRACMPFTLWRVLLIVWSVGGFLATALFPRI
                     QKLLEISTLTEQTLPVYGVMMLVFTVIFILTSRYQARK"
     gene            17485..18162
                     /locus_tag="VQU30_001033"
     CDS             17485..18162
                     /locus_tag="VQU30_001033"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000624068.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (adenine-N(1))-methyltransferase"
                     /protein_id="HET2447156.1"
                     /translation="MISKRLELVASFVSQGAILLDVGSDHAYLPIELVERGQIKSAIA
                     GEVVEGPYQSAVKNVEAHGLKEKIQVRLANGLAAFEETDQVSVITIAGMGGRLIARIL
                     EEGLGKLANVERLILQPNNREDDLRIWLQDHGFQIVAESILEEAGKFYEILVVEAGQM
                     KLSASDVRFGPFLSKEVSPVFVQKWQKEAEKLEFALGQIPEKNLEERQVLVDKIQAIK
                     EVLHVSK"
     gene            18149..18946
                     /locus_tag="VQU30_001034"
     CDS             18149..18946
                     /locus_tag="VQU30_001034"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000881127.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Nif3-like dinuclear metal center hexameric
                     protein"
                     /protein_id="HET2447157.1"
                     /translation="MLASEVIHAYEAFCPQEFSMEGDSRGLQIGTLDKGIQRVMVALD
                     IREETVAEAIEKGVDLIIVKHAPIFRPIKDLLASRPQNQIYIDLIKHDIAVYVSHTNI
                     DIVENGLNDWFCQMLGIEETTYLQETGPERGIGRIGNIQPQTFWELAQQVKQVFDLDS
                     LRMVHYQENDLQKPISRVAICGGSGQSFYKDALAKGADVYITGDIYYHTAQDMLSDGL
                     LALDPGHYIEVLFVEKIAALLTQWKEKKGWELEILPSQASTNPFRHI"
     gene            18963..20066
                     /locus_tag="VQU30_001035"
     CDS             18963..20066
                     /locus_tag="VQU30_001035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397627.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-binding oxidoreductase"
                     /protein_id="HET2447158.1"
                     /translation="MKKVAIIGAGIVGATAAYYLSRESDLEVTVFDHEQGQATKAAAG
                     IISPWFSKRRNKAWYKMARLGADFYVDLLADLEKSGQKIDFYQRSGVFLLKKDESKLE
                     ELYQLALQRREESPLIGQLAILDQASANELFPGLQGFDRLLYASGGARVDGQLLVTRL
                     LEASHVKLVKEKVTLTPLASGYQIGEEEFEQVILATGAWLGDMLEPLGYEVDVRPQKG
                     QLRDYQLVQDMEAYPVVMPEGEWDLIPFAGGKLSLGATHENDMGFDLTVDETLLQQME
                     EATLTHYLILAEATSKSERVGIRAYTSDFSPFFGQVPDLTGVYAASGLGSSGLTTGPI
                     IGYHLAQLIQDKELTLDPENYPIENYVKRVKSE"
     gene            20073..20264
                     /locus_tag="VQU30_001036"
     CDS             20073..20264
                     /locus_tag="VQU30_001036"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2447159.1"
                     /translation="MKIKEQTRKLAAGYSKHCFEVVDRTDEVSSKHCFEVVDRTDEVS
                     NHTHGKATLTWFELDFRRV"
     gene            20367..21386
                     /gene="galE"
                     /locus_tag="VQU30_001037"
     CDS             20367..21386
                     /gene="galE"
                     /locus_tag="VQU30_001037"
                     /EC_number="5.1.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006153709.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose 4-epimerase GalE"
                     /protein_id="HET2447160.1"
                     /translation="MQEKILVTGGAGFIGTHTVIELIQAGHQVVVVDNLVNSNRKSLE
                     VVERITGVEIPFYEADIRDTATLRDIFKQEEPTGVIHFAGLKAVGESTRIPLAYYDNN
                     IAGTVSLLKAIEENNCKNIIFSSSATVYGDPHTVPILEDFPLSVTNPYGRTKLMLEEI
                     LTDIYKADSEWNVVLLRYFNPIGAHESGDLGENPNGIPNNLLPYVTQVAVGKLEQVQV
                     FGDDYDTEDGTGVRDYIHVVDLAKGHVAALKKIQKGSGLNVYNLGTGKGYSVLEIIQN
                     MEKAVGRPIPYRIVERRPGDIAACYSDPAKAKAELGWEAELDITQMCEDAWRWQSKHP
                     NGFED"
     gene            21388..22341
                     /locus_tag="VQU30_001038"
     CDS             21388..22341
                     /locus_tag="VQU30_001038"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014632375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HET2447161.1"
                     /translation="MMISIIVPCLNEEEVLPLFYQALEALLPDLETEIEYVFVDDGSS
                     DGTLELLKAYREQNPAVHYISFSRNFGKEAALYAGLQYATGDLVVVMDADLQDPPSML
                     FEMKNVLDKNVDLDCVGTRRTSREGEPFFRSFCAVLFYRLMQKISPVALPSGVRDFRM
                     MRRSVVDAILSLTESNRFSKGLFAWVGFKTYYLDYPNVERQAGKTSWSFRKLFFYSIE
                     GIINFSDFPLIIAFVAGLLSCFLSLLMTFFVVVRTLILGNPTSGWTSLMAVILFLGGI
                     QLLTIGILGKYISKIYLETKKRPLYLIKEKSDDRLKKIEFI"
     gene            22493..23158
                     /locus_tag="VQU30_001039"
     CDS             22493..23158
                     /locus_tag="VQU30_001039"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000949235.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2447162.1"
                     /translation="MLSKEDYTEEIGLIKKQNYVEAELYPIVADIIKPTLKDSLSKRY
                     VFGRQRRGLGQIYYGLSNFPDIVILDKTYENKSRKSIKIEEWKKLRGCVEVKNLNYSL
                     ITEEKIKSTISNSFEHITGEMEQLTGEMGQLIGDLLWYKKVIYTNGIEWRFLSLDDKE
                     EIDNTIVEVVNKRIETEEAGNSFDWWKNIKDLSFNYTDICLSKDCRQEWNEFVKRVKE
                     IEW"
     gene            23197..23298
                     /locus_tag="VQU30_001040"
                     /pseudo
     CDS             23197..23298
                     /locus_tag="VQU30_001040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677122.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="group 2 glycosyl transferase"
     gene            complement(23349..23555)
                     /locus_tag="VQU30_001041"
     CDS             complement(23349..23555)
                     /locus_tag="VQU30_001041"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001843159.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferredoxin"
                     /protein_id="HET2447163.1"
                     /translation="MKITLIPERCIACGLCQTYSDLFDYHDNGIVRFYDDPDQLEKEI
                     SPSQDVLEAVKNCPTRALIGNQEA"
     gene            23607..24083
                     /locus_tag="VQU30_001042"
     CDS             23607..24083
                     /locus_tag="VQU30_001042"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399345.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM domain-containing protein"
                     /protein_id="HET2447164.1"
                     /translation="MAKEPWQEDIYDQEESRAERRHRNHGGADRMANRILTILASIFF
                     VIVVVMVIVLIYLSSGGSNRTAALKDFHDSDASVVQISSSSSSQPEQSSEPESTSSSS
                     EEAANPEGTIKVLAGEGEAAIAARAGISIAQLEALNPGHMATGSWFANPGDVIKIK"
     gene            24092..24763
                     /locus_tag="VQU30_001043"
     CDS             24092..24763
                     /locus_tag="VQU30_001043"
                     /EC_number="2.7.4.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000849376.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="(d)CMP kinase"
                     /protein_id="HET2447165.1"
                     /translation="MKTIQIAIDGPASSGKSTVAKIIAKDFGFTYLDTGAMYRAATYM
                     ALKNQLGVEEVEALLALLDQHPISFGRSETGDQLVFVGDVDITHPIRENEVTNHVSAI
                     AAIPEVREKLVSLQQEIAQQGGIVMDGRDIGTVVLPQAELKIFLVASVDERAERRYKE
                     NIAKGIETDFETLKKEIAARDYKDSHRETSPLKQAEDAVYLDTTGLNIQEVVEKIKAE
                     AEKRM"
     gene            24894..25232
                     /locus_tag="VQU30_001044"
     CDS             24894..25232
                     /locus_tag="VQU30_001044"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002920966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alkylphosphonate utilization protein"
                     /protein_id="HET2447166.1"
                     /translation="MNNLPNCPKCNSEYVYEDGALLVCPECAHEWNPAEVAEVEEGLV
                     AIDANGNKLADGDTVTLIKDLKVKGAPKDLKQGTRVKNIRIVEGDHNIDCKIDGFGAM
                     KLKSEFVRKI"
     gene            25235..25864
                     /locus_tag="VQU30_001045"
     CDS             25235..25864
                     /locus_tag="VQU30_001045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000033944.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Pr6Pr family membrane protein"
                     /protein_id="HET2447167.1"
                     /translation="MSKHYKLVFYSRIFLFLAAFTGVYLEITKHGGFGMLLYYTVLSN
                     LLVTIFTLYLLKVMSRVGENWQRPSLLRLKGGVTMSIMITCVIYHFLLAPIATNFYTL
                     ENFLCHYIVPIWFLADTLFFDKQGQYKIWDPAVWTILPFLYMMFALFNGLVLKLNIPN
                     AKDNPFPYFFLNVNKGWNVVFKWCLIIFVAYMVAGFIFYFIKQIKRKSS"
     gene            26104..27255
                     /locus_tag="VQU30_001046"
     CDS             26104..27255
                     /locus_tag="VQU30_001046"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000808687.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HET2447168.1"
                     /translation="MKQFLERASILALSLVLITSFSISSALPAMFDYYQGYSKEQIEL
                     LVSLPSFGIMMMLLLNGFLEKIFPERLQISLGLLILSLSGTAPFWYQAYPFVFGTRLL
                     FGLGLGMINAKAISIISERYQGKRRIQMLGLRASAEVVGASLITLAVGQLLAFGWTAI
                     FLAYSAGFLVLPLYLLFVPYGKSKKEVKKRAKEASRLTREMKGLIFTLAIEAAVVVCT
                     NTAITIRIPSLMVERGLGDAQLSSFVLSIMQLIGIVAGVSFSFLISIFKEKLLLWSGI
                     TFGLGQIVIALSSSLWVVVAGSVLAGFAYSVVLTTVFQLVSERIPAKLLNQATSFAVL
                     GCSFGAFTTPFVLGAIGLLTHNGMLVFSILGGWLIVISIFVMYLLQKRA"
     gene            27568..28317
                     /gene="truA"
                     /locus_tag="VQU30_001047"
     CDS             27568..28317
                     /gene="truA"
                     /locus_tag="VQU30_001047"
                     /EC_number="5.4.99.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000199202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA pseudouridine(38-40) synthase TruA"
                     /protein_id="HET2447169.1"
                     /translation="MTRYKATISYDGYAFAGFQRQPHARSVQEEIEKTLTRLNKGQAI
                     TVHGAGRTDSGVHALGQVIHFDLPYQMDEEKLRFALDTQSPEDIDVISIELVADDFHC
                     RYAKHSKTYEFTVDRGRPKNPMRRHYATHFPYPLDVERMQIAIKKLEGTHDFTGFTAS
                     GTSVEDKVRTITEASLIVDETGQFLTFTFSGNGFLYKQIRNMVGTLLKIGNNRMPVEQ
                     IDLILEKKDRQLAGPTAAPNGLYLKEIRYEE"
     gene            28307..29080
                     /locus_tag="VQU30_001048"
     CDS             28307..29080
                     /locus_tag="VQU30_001048"
                     /EC_number="2.7.4.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional hydroxymethylpyrimidine
                     kinase/phosphomethylpyrimidine kinase"
                     /protein_id="HET2447170.1"
                     /translation="MKNNRILALSGNDIFSGGGLSADLATYTLNGLHGFVAVTCLTAL
                     TEKGFEVFPTDDTIFQHELDSLRDVEFGGIKIGLLPTVSVAEKALDFIKQRPGVPVVL
                     DPVLVCKETHDVAVSELCQELIRFFPYVSVITPNLPEAELLSGQEIKTLEDMKTAAQK
                     LHDLGAPAVIIKGGNRLSQDKAVDVFYDGQTFTILENPVIQGQNAGAGCTFASSIASH
                     LIKGDKLLPAVESSKAFVYRAIAQADQYGVRQYEANKNN"
     gene            29058..29519
                     /locus_tag="VQU30_001049"
     CDS             29058..29519
                     /locus_tag="VQU30_001049"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000814967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HET2447171.1"
                     /translation="MKQTKTTKIALVSLLTALSVVLGYFLKIPTPTGILTLLDAGVFF
                     AAFYFGSREGAVVGGLASFLIDLLSGYPQWMFFSLVNHGLQGFFAGFKGKSQWLGLIL
                     ATIAMVGGYALGSTLMNGWAAALPEILPNFMQNMVGMIVGFILSQSIKKIK"
BASE COUNT         8719 a         5366 c         6692 g         8981 t
ORIGIN      
        1 taaattttta gattgtggaa tttttttcaa cttaattctt gatttttttt ctaaattgtt
       61 atatacttaa tttacgggat aacagaatcc cgtcagaaag gggtgataat atgggaaaag
      121 agaatgttag aatgcgttta gcgtctgaat ccagacagat attagataag cttaaagatg
      181 atgtttacaa taaattaggc tatgaagtaa gctattccag tattgttagt caagctgtta
      241 gagaatacgt tcctaaaaaa gaacgtatag attggataaa attaaaagag acagctatac
      301 ctttttcatc gttaaaacag agcaataatt gggagtacca gacatcactt atgttagaga
      361 aagatgtatt aatcttactg tctgaactac aaaatttttt cttagatgtc ttccaagcga
      421 aacgtataca tagggcattt tgtatacgtc tatgtttgag agcgcaattt ttattaagta
      481 ataatgattc ttaatactat caatattaat gcggagtgta atgctccgca aaaataaaac
      541 ctattacggg ataaaaacac tactttattt aggatggaaa taagaacgta ttttttacta
      601 atattgttta gaaaggagtt tctttatgac accagaagaa caaactgctt tggaatactt
      661 ttatgaggaa ctcgagagtt acggtgaaga tgagcaagga gaggtctttg atttgtatga
      721 taattaaatc atctccatag tttctgagaa taattgagaa actatactct aaatcatagg
      781 tttatgtaaa gctagatata cacaaaagga ggtacgaatg aagatgaaag ctagagcttc
      841 accgttgaat tgattttgtt tctagaaaaa atcaataatt agaaaaatac gaggtaaaaa
      901 aatgaataga aatgtactaa attttctgcg aacagaaagt gctgaaagag ttagtcttta
      961 tatagacaag gctaatagat tggagggcga tgtaactcta ctcgcaccta gttctcaaga
     1021 tttggaagat attaaaaatg ctatgttttc caatcctaat ctcgagctaa aagtagcgag
     1081 actggatgtg atgaagaaaa tagcatatgc ttctacaaga aatcattatt taacaggggc
     1141 tacgattttt ggggatattt cgaaaggaac atacaattgt gatcctaaaa gttatgtcta
     1201 atataaggga ggttaatccc tccccttgtt tttgaaaatc gaaaggaaaa gtataaaaat
     1261 gaaagttaat gaatatttct ggagaacgag ctgtcttata ctaaaaaaga agaaatcgat
     1321 aaaatagtat acgtgttaga gatgtgtttg tcgtaaaagt ctggatagtt ttctcttagg
     1381 tagtcagctg tcatataata aaaagtagaa tggcaagcag tgatgattgg cataagagat
     1441 gaaaaacgct gagaactaat gaaggctaag agaacaaaaa atagaaaatc aatggtgaga
     1501 acccctaaat agtagaagcg aatcttttta ttgatttgag gataaatctc agcgaattga
     1561 tgtttgagtc ggacgaccaa gagaaatagc aggagtcctt gagcaaggaa gaaaattaaa
     1621 ccagagagca agagccactc aaaagatgtc tcgagtctag tgataaaaaa tgcaaatagt
     1681 agcaaatcaa taactgcaat tgctataaaa tggattctat agagtttttt catgacaaga
     1741 cctccctctt ttatctaact tcattctact ctaaaagaat gggagttaca actaaaatga
     1801 taaaaatagc agaggggaga ttctcttaag ttggctagta ttctttattt gagtttcctt
     1861 ctattatcta acttcttcat cattccagac aaataaagct ccgattgcat tgaggatata
     1921 aaagatgtat ttaccgatat tggcgaagtt tccttgaata ccagcttttg tcagctgaac
     1981 gaaattgtaa atcaaccaaa agccccactg tccctcattg ccaatgcatt caaagcattg
     2041 gcaatgaggg acagtgcaaa ggcaatagtt gttacgtagg caaggagatt catcttgccc
     2101 ccatatccga tatagttggt cacaaaggca aagaggaagg cgatgatgga aatgatgatg
     2161 gccgccaatt ttacctgttt ttggctcatt tggttgggtc tgccttcttg cgaagctttc
     2221 catttcttta tagcaaaggt ataaatgagg aaggtgacgg gataggtaat gatggccgcc
     2281 ttatttccaa ggatataatc aatagcaccg gacaaaatgg tattaacaat accaaagtaa
     2341 ttttcccatt tgcttaattt ccccgtgaaa cgagtggaca acatggaaat cccaacgttg
     2401 gttacggaaa tcaatccaaa gggtacaaga gctgtccatg gtccccagtc tacaaattta
     2461 tcgaggcgtg agttgaggta accagatgca atcgcaatcc aacgaccaaa gcaaccccga
     2521 agaggtcaaa ctatttagat gtagcaaaaa tttttagtga ttttttcata ggttaaacta
     2581 cctttctttt tttcaaatat tctcccattt ttttttcaaa tattctacca ccaaatgaaa
     2641 gtaaaataaa atgatagaaa taaaaccctg aaaataaaac tttcagggtt ggtaggggac
     2701 ttgagaaatt agttgatttt ctcgacatag agttgttttg caatgtccat attcacttgt
     2761 aaatcctcgt cgttactgag gatagtgaag gtattgctga agccatcaaa ctgcttaact
     2821 tggagctggt caccgatgtg aagtgagtgc ttgtccagat aatggagaat gtcaaaacta
     2881 tcgtgcatcc gagtcaggcg gtaggcgcca gcttccttga tatcagctag tgggaggtta
     2941 ttgatttcaa cgaggagttc tcccttggca ggaatagttc ctccgtgggg gcaggtttta
     3001 gggaaaccta gcagtttatc tagtctttcc acgaacaggt cagagacagt gtgttccaag
     3061 acctcagctt cctcgtgaat ctggtcactt gtatagtcta aatgatgaac tagaaaaact
     3121 tcaatcaagc ggtgcttacg atagagctca gagaccagtt tgagaccgag gtcagtcagt
     3181 agatagccac attccttgtc ctttaggatg agattttcac ttttcattcg tttgatcatt
     3241 tcagttacgg cagggggaga gacttgcatg cgagccgcaa tttccttgtt ggtaatctta
     3301 tgcaggtcta tgccaatttc ataaatacat tttagatagt cttctttgtt tggggtcatt
     3361 cgtttcctct tgtctaatat ctttatctag tatatcaaaa aaagctagat ttctctagct
     3421 gtgacttttt atgttatact tattgcaaga gaaaaaacga ggagatggat atgacgaaaa
     3481 tagctcttct ttcagatatt catggaaata ccaccgcctt ggaggctgtt ttggcagatg
     3541 ctcggcagct aggagtggat gaatactggc ttttgggaga tattctcatg ccagggacag
     3601 ggcgtagaag gattttggac ttgttggatc aactaccgat tacggctaga gttttgggaa
     3661 actgggaaga cagtctttgg catggtgtcc gtaaggaatt ggatagtact cgccctagtc
     3721 aacgctatct cttgcgccag tgccagtatg ttttagagga aatttcccta gaagaaattg
     3781 aagtgctcca caatcaacct cttcaaattc atcgtcagtt tggggatttg acagtgggaa
     3841 ttagccatca tctgcctgat aagaactggg ggcgagagtt gattcatact ggcaaacaag
     3901 aggaatttga ccgcttggtg actcatcctc cctgtgatat tgctgtttat ggacacattc
     3961 accagcagtt gcttcgttac gggactggtg ggcaattgat tgtcaatccg ggttcgattg
     4021 gccaaccttt ctttttggac gctcagctac ggaaggactt gcgggcccag tatatgattt
     4081 tggagtttga tgacaagggc ctggtagata tggacttccg acgggtagat tacgatgtgg
     4141 cagctgaatt gcagctggct aaagacctga gacttcccta ttttgaggtt tactatgaaa
     4201 gtctggtcaa tgggatccac catactcatc atcaggaatt tttgagagaa ttggctcaga
     4261 aagagggttg cgatcgggag ttagacgact ggttgaaaag tggtaacgat tgacattaca
     4321 actaaaaagg gtataataat agaaaaagaa gagtagaggc agggtagcct cgtaaaaagg
     4381 agaagaggat gcaaattcca agtagattta ccattgcgac tcatatgctg ataatcattg
     4441 ccctcgaggg gaagaaaagc aaggtgacca gtgattttct ggctgctagt gtcggggtca
     4501 atcctgtcat tatcagaaag atcttgtccc agttgaagaa ggcagagctg atttcagtag
     4561 cgcgtggaac gggcggaaca gatattgtca aggaccttaa ggatattagt cttttagatg
     4621 tttatcaggc ggtcgaatgt cttggtaaga caggtcaact cttcagtttc catgacaatc
     4681 cgaatccaaa ttgccctgta ggagctcata ttcatgatgt tttggatcaa aaattggaga
     4741 gaattcagtt gactatggag gcagaacttg gtcaaaccag tctagaaaaa gtcgtggccg
     4801 atgcagagag tcagatgaag gattaagagg gataaatgcc ctcttttttc tttggataat
     4861 tatgataaaa tgtagctatt aaaggagtaa gaaatgtatc tcgttatagg aattgtatta
     4921 gcctttatag tgtcattttg gaaggataat agaagtttgt ggaatccagt attattttta
     4981 ttatccctca tttcaagtta tttttatcta tcctaccttt tttataaaaa tggatacgag
     5041 aatgttcagt tagcttttta tgtatttgcc tttgtcttac ttcctttttt gctttttcta
     5101 agtggcatct ttttaatcta taatggggtc attttgttga agcgagaggg acgttccaag
     5161 ccccattatc tctcaatgct ctttgatttt tattgactat tagattctat ttaaaaagac
     5221 ttagaatgca catgaaagta tgtattctag gtcttttgtt ttgtatacat ttaattttca
     5281 agagtattat ctatttttcc atgcctggta acgagtatca atcaataact gggtaaggcg
     5341 acccaaggtt tctctttctt ctggagtgag ggattgagct tggacaaaga gatgatgaat
     5401 gtattcaagc gcctttaagg aagccaagtc attgatagag ctaataccag cctcaagaat
     5461 agtgccaaag aagaggtcga agtagagctg aagttcttcg tcagggactg tggccaccca
     5521 ttctttaaag gttgtgtcta cttgctggct atcactgttg gtcttatcca gttggacgaa
     5581 gtgcttgtcc tcaatctgcc aactaaaggt atcgtgctgg gcgatgccac ccagggcagt
     5641 actctgaacg atgattttgt gagcaggaat ttccagcatc ataccgataa tggaaccttg
     5701 tggaatgaat atcttgcttc tatccattat cctttgataa cccgcagtct gtgtcaattc
     5761 ttgatggaga ccaggtgcat caaatgtata aactgctgtg atctgatttt gcaaactttg
     5821 ctcaatttgg ctagcagcat agatagcgag atttcctccc ttggaatgcc cagctagaat
     5881 aaccttttgc ttaggatgat gggcaaaaaa gttctttaaa tagcgaaggg cgtgcttttg
     5941 agcaggaatt tccttcatat aggtcaggtg gaaatcttcc ttccagccaa tgatactgtc
     6001 atctgtccca cgaaagacaa tcagataggt atcgaggctg acacgataag tcatagccgc
     6061 aaattgcttt tgcagttcag ggtcgatgtc gttgataaaa tgggagagtt tgcaattttt
     6121 gaagcgcttg tgttgagcca atttatctaa taattgaagg cgatttttgc tagtaagcat
     6181 ggtgggctct cttggaacct gaggtgctag atctaaaaga cgttgaggaa gtgtggagac
     6241 cagattatca aaggagaggt aggtgatttc tattaaggtt agaatgtcta actcattcaa
     6301 gggaaggtcg taataagaat catatgcgac atctttcaga tagtcaaaaa tattggccat
     6361 aagagctcct ttctttttat ttatcttagc aaatttccct caaattagct agtagcatag
     6421 cctgtttgca ctggctaaaa acaggctatt tcaaattcag tttcagacca tctagcatgg
     6481 aaaaatctgt tataataatg gaaaaggaga agcgcatgca caagatttta ttaatagaag
     6541 atgatcaggt cattcgtcaa cagattggga aaatgctctc tgaatgggga tttgaagtgg
     6601 tcctggtaga agactttatg gaagttttga gtctatttgt tcagtcggaa cctcatctgg
     6661 tcctcatgga tattggtttg cccttgttta atggttatca ctggtgtcag gaaatccgca
     6721 agatttccaa ggtacctatc atgtttcttt cttcgagaga ccaggctatg gatattgtca
     6781 tggcaatcaa tatgggggcg gatgactttg tgaccaagcc ttttgaccag caggttcttt
     6841 tagctaaggt tcagggcttg ttgcgtcgtt cctatgagtt tgggcgtgat gagagtttgc
     6901 tggaatatgc tggtgttatc ctcaatacca aatccatgga tttacattat caagggcaag
     6961 tcttgaattt gaccaagaat gaattccaga ttttacgcgt gttatttgag catgcaggca
     7021 acatcgtagc acgtgacgac ctgatgcggg aactttggaa cagtgacttt ttcattgatg
     7081 ataataccct ctctgtcaat gtggctcgtt tgcgtaaaaa gttggaggag cagggattgg
     7141 taggatttat cgagaccaag aaaggaatag ggtacggatt gaagcatgct tgattggaaa
     7201 caattttttc tagcctatct gcgctcccgt agtcgtcttt ttatctatct gctttctttg
     7261 gcatttcttg tcttactctt tcagttttta tttgccagtc taggaattta cttcctctac
     7321 tttttcttct tgtgttgctt tgtaaccatc ttatttttca cttgggacat attggtggaa
     7381 atgcaggtct atcgccagga acttctctat ggagagaggg aagccaagtc tcctttggaa
     7441 atagctttag cagaaaaatt agaagcgcgt gagatggaac tctatcagca gaggtcaaaa
     7501 gcagaaagaa aactgacgga tttgctggat tactatacct tgtgggtcca tcagataaag
     7561 acccccattg cagccagtca actcttagtt gcagaagtgg tcgaccgcca actgaagcag
     7621 cagctagaac aggaaatttt caaaatcgac tcttatacca acctagtttt acagtacctg
     7681 cgtttagaaa gtttccatga tgatttgctc ttaaagcagg ttcaaattga ggacttggtc
     7741 aaggaaataa ttcgtaaata tgctcttttc tttattcaaa aaggcttaaa tgtcaatcta
     7801 catgaccttg ataaagaaat cgtgacggat aaaaagtggc tgctagtggt tattgagcaa
     7861 atcatctcaa acagtctcaa gtacaccaag gaaggtggtc tggagattta tatggatgac
     7921 caagagattt gtatcaaaga tacgggaatc gggataaaaa acagtgatgt cctccgagta
     7981 tttgaacgtg gcttttcagg atacaatggc cgtttgaccc agcagtcctc tggacttggc
     8041 ctttatctat ctaagaaaat ttctgaagaa ctggggcacc agattcgtat cgagtctgag
     8101 gtcggaaaag gaacgacagt gcggattcag tttgctcaag tgaacttagt ccttgagtaa
     8161 aaatagatga gaaaaagcct ccagattgga ggcttttatg ctagactctt atttctcaac
     8221 gcgtgatttg ttggcgatat cagctaggat agcttgaaca aaattatcaa ctgagacagt
     8281 ttgtgtttct ttttggccgt agcgacgaac gttgactgtt tcgtcttcca tttctttgtc
     8341 tccaacaatt aattggtaag gaatcttgct ggtttgtgaa gcacggatct tgaactgcat
     8401 tttttcattg cgctcatcta cgtctgcacg gacaccgcgg tcacggagtt tcttggctac
     8461 ttcccaagcg tagtccacgt gtttttcgtt agatactggg atgagggtta cttggtgtgg
     8521 tgccagccat gttgggaagg cccccttgta gttctcaatc aagatagctg tgaagcgttc
     8581 catagttgag ataaccccac ggtggatcat gactggacgg tgatcttcgc catcagctcc
     8641 gatgtatttg aggtcgaagc gttctggcaa caagaaatca agttggatag tagaaagggt
     8701 ttcttctttt ccaagggcag ttttaatctg gatatccaat tttggtccgt agaaggctgc
     8761 ttcaccttcg gcttcaaagt agtccacgcc catttcatca agagctgcac gaagcatggt
     8821 ttgggcattt tcccacatct catcgttatc aaagtactta tgagtatctt gagggtcacg
     8881 aagagagagg cggaagcggt agtcagtcaa gttgaagtct tcataaacat cgataatcaa
     8941 ctgaagggca cgttggaatt cttcttggat ttgttctgga gtaacgaata ggtgaccgtc
     9001 gttgagtgac atttcacgta cacgttgaag gccagtgagg gcaccagatt tttcgtaacg
     9061 gtgcatcata ccgatttcag cgatacggat tggcaattca cggtaagagt gaacatggtg
     9121 tttgaaaact tggatgtggt gcggacagtt cattggacga aggacaaatt cttccccgtc
     9181 acccatgtcc atggttggga acatgtcttc ttggtaatga tcccagtgac cagaagtctt
     9241 gtaaagctca acagaagcaa gtggtggagt gtagacgtgt tggtagccag aagccaactc
     9301 tttgtttacg atgtagcgtt ccaattcacg acggatagtc gcaccatttg gcaaccagaa
     9361 tggcaaacct tgtcccactt cttgtgaaat cataaagagg tcaagctctt taccaagttt
     9421 acggtggtca cgttccttag cttcttcacg catttgaagg tagtttttca agtctttctt
     9481 gtcaaaccaa gctgtaccgt agatacgttg catcatagcg ttgtcgctgt ttccacgcca
     9541 gtacgcacca gctacatgga gaaggtggaa gatttggata cgacctgttg atggaacgtg
     9601 aggtccacgg cagaggtcta catattcacc ctgacgatag atagtcaaac cgccttcgtc
     9661 ttctgagtgt tcttcaatca attccaactt gtaagggtca tttttgaaga tttcacgtgc
     9721 ctcgtcttta gtcacttctt cacgaataga tgggaagttt tctttgacga ttttttgcat
     9781 ttcttcttcg atacgaggaa ggtcttcgtt agagatttga ccagctgtgt tgtcagtatc
     9841 gtagtagaaa ccatcttcga tggctggacc aactcccaag tgaatgtctg ggaaaagacg
     9901 acgagctgct tgggcgaaca agtgagctgc tgagtgacgc aagattggaa gggcatctcc
     9961 gtgatcaggt gtcacaattt cgatgcttcc atcttcagtg atagcgcgag tagtgtcgat
    10021 gagtttgccg ttgaatttac cagccaaggc ttttttagct agggaattgc tgatagattg
    10081 ggcaatttca aaagttgtta cgccagattc gaattcacga atagcgccat ctgggaaagt
    10141 aatgttaatc atgatgttct ccttttttat tatttcatag tttctaagca ttgatttttt
    10201 atcagcagac tacttccaag ttctaacgtt caattgcttt tctttatcag agaggaagtt
    10261 ttccatttcc gtcagaatat ctatatccaa acgttgagaa agttctaata gtcaccagat
    10321 attttctgaa agtttttgtt ccagtgtgta gggtgtttca tcatagtagc gtccttgctt
    10381 tgtcatcacc agtcattgga aatttccaat atcattagat aaagccaaga ggtcttcttc
    10441 taccgtccac ttgaaatcat gatgcttaac ttccagttcg tgataagctt gtcggattgc
    10501 ccaactgcgc tccactaatt cttgcaactc cataattagt atcctaataa aaaaatgcga
    10561 catcctcgaa aggacgtcgc aacgtggttc caccttcatt tatgtacctc aaaagagagg
    10621 gacacctctg atcggctcta acgtggccac cgttttatgt tttcataaaa aactcaagag
    10681 tagtatcagt ttagacttcc tatgcgtttc cagcaaccac gcactctcta gtagaaaggg
    10741 actaagtgac ttgtctctat ggattattat agcatgattg tgagattttt caaggatttt
    10801 gtgaaagttt tttgtttttc attttttgta gaatatgctt gatgctaata ccagaatcca
    10861 tgcccaccag agcaactgtt tcatagatta gcaagtaaat tagtataaac acaccaaagg
    10921 ttatgatagt aaagtaaaag agcagtccgt taccaactaa ccatcaaagt gagaaacgga
    10981 aacggtagct atagagtaac gatacaatca agattaccat aggtgtaaag aagagaagat
    11041 tgtttatata gagtcccttg agtgtaaggg ggtcagaaac aactagcaag aacaactcat
    11101 aaagtggcca ataaaagaat aatatgacca gatagtaggg gagatgggaa tagaatctac
    11161 gcatgataat cacctcgttt taaaaaaaca gacaacttag atctcttgct atgattatta
    11221 tagtatgttt aaaacaagaa agtaaatttg ttgacaaaga agatttttct tttcactaga
    11281 atcatggtta gttttcttgg tagaaatatt ttgataataa ttaagcaaga ctattgacat
    11341 tgattattaa gagtgtcaca attgttgtaa ctaaaataat tacaacaaga ggggtataaa
    11401 aaatgaaact agcagttatt gcagcaaatg gacaagcggg gaaggcaatt gttgaagaag
    11461 cagtcaaacg aggacatgaa gtaacggcta ttgttcgttc tgaaaacaaa agtcaagctg
    11521 agtctattat taaaaaagat ttatttgagt tgacaaaaga tgatcttact ggatttgatg
    11581 ctgttatttc agcgtttggt gcttatacac cagatacgct accgctccac agcaaatcaa
    11641 tcgaactatt taatcagctt cttgctggaa cacagacacg ttttctagtt gtagggggat
    11701 caggaagcct ttatatagat gaaacaaaaa cgacacgact tttagatacg cctgattttc
    11761 ctgaagaatt taagtcacta gcaaaagctc aagcggatga attggatctt cttcgtacaa
    11821 aaaataatct caactgggct tttgtcagtc ctgctgtaga ttttattccc gatggtgaaa
    11881 aaacaggaaa ctacattcta gcaggagaaa tttttactac taatgaaaaa aggaataagc
    11941 cagattagtt atgcagatta tgctattgga ttggtagatg aacttgaaaa aggtcatcat
    12001 ataaaagaac gtatctcttt acttgaaaaa taataactat gagagtatta atgtttgaca
    12061 gaaaatttaa atcttggtag aatagggatt gtcgtaaaga caaataactt cttcttggtt
    12121 acaggcatgc caacctgtca ctcggatgaa gccaaataaa aaggagaaac atcatggcaa
    12181 tctcaaaaga gaaaaaaaat gaaatcatcg cacaatatgc acgtcacgaa ggtgatacag
    12241 gttcagtaga ggttcaagtt gctgtcctta cttgggaaat caaccacctt aatgaacaca
    12301 tcaaacaaca caaaaaagac cacgctactt accgtggatt gatgaaaaaa atcggtcgcc
    12361 gtcgtaactt gcttgcatac ttgcgtaaaa acgacgttaa ccgttaccgt gagttgatca
    12421 actctctagg acttcgtcgc taattcaaga tacaaaggct gtcaaaagca caaagtaaaa
    12481 ataggaaaat ttacgaagaa acttcagttt ctaggagatt ttatcttttt tgccaagtgc
    12541 ttaggccgtg ttcaattgag catatcttga taatgaagct actctaaatt gggtagcttt
    12601 tttgtgttgt caccttacct cgatatactc aagtataatc tttggttacg gttcctagca
    12661 ctgtaaggta aaataaacca gcttttctcc cttcggggag attttttttg tttcactgaa
    12721 agtttcgtac gatcttcgcc tcgtcgccta gtctataaac gatttatcta gcaagaatca
    12781 tgatgctaag ggcgtcaaaa atccgtatga aaatagggaa atgacacagt gttcgatgag
    12841 cacaaggagt ttcatctttt tcactaggat tttagcccgg actcaaatca gctctctgac
    12901 ttcagagggc ttttttattg aggttttatc ggtaacaatt ttggagacta caaaaacctc
    12961 aaacggtatc agctaattac accataaagg tgcgcagtta ctcggctttt caagccgagt
    13021 agttgtatgc aagcccccta gaagagccca ctctttacaa agtaaagtat agtatgttat
    13081 actttacatg gaagtagtca ctgaattcca gttagaaatt actttgtaac tacgttttga
    13141 ggaggagtaa aatgctttcc tacgttcgat attacccact agcgatagct aaattaatgt
    13201 gtctgtgctc tcctaaaatc tgctgattta ttactgacta atacaggagt ttttttttat
    13261 gggacagaca atcatatctg ctattggtgt ttatatttcc accagtatcg attatttaat
    13321 tattttaatt attttatttg cacagctatc acagaataaa cagaaatggc atatttatgc
    13381 ggggcaatat ctaggcacag gcttacttgt aggggcgagt ttagttgctg cttatgtcgt
    13441 taatttcgtg cctgaagaat ggatggttgg attgcttggt ttaatcccta tctatttagg
    13501 gattcgcttt gcaattgttg gagaagatgc ggaagaagaa gaggaagaaa ttattgaaag
    13561 attagaacaa agcaaggcaa atcaactgtt ttggacagtt acattgctga caattgcgtc
    13621 tggcggagat aatttaggta tctatatacc ttattttgct tcgttagatt ggtcacagac
    13681 cctcgtggcc ttgcttgtgt ttgtaatcgg cataattatc ttttgcgaga ttagtcgggt
    13741 gttatcttct attccgttaa tattcgagac aattgaaaaa tacgagcgaa tcattgtgcc
    13801 cttagtattc attctacttg gactatacat catgtatgaa aatggcacga tagagacttt
    13861 tctgatcgtg tagatttttt tgtttcacta ggattttagt ccgagctcaa atcagctctc
    13921 tgattttcag agggcttttt cattgagtat aaatggacaa tcttaaagtt actctattgt
    13981 agagtggctt ttgatttgat taggagattc ttataaatat agtaaaatga aataagaata
    14041 ggacaaatcg atcaggacag tcaaatcgat ttctaaaaat gttttagaag tagaggtgta
    14101 ctattctagt ttcaatttga tatataaatg aaaaccttag ctgtttggcc aaggttcatt
    14161 tcttctatgc aagttcttct cttttcttat ctgggttcca gatgaagctt gcgataaagc
    14221 taaagatgat ggttaggata gcgagaataa tagcaaggat gagggcaggg atgcggataa
    14281 accaccagag tggatttggt tttttatcat tgtgccattg tttcgtttct tcgtccagac
    14341 gttggaattc tgtttgaata cgattggcga ctgtttcaat gccttcatca ttcattttct
    14401 tgatatctga gatatcgatt ggatttccaa agttcatatc gacacgttca cggctaatca
    14461 agcccttcaa agtcatggga ccggtgtagg taaccggcat gatacggacc ttggccattt
    14521 tggcaatcag tgctgcgccc cccttgacat cgtttgagtg gcggctacca cttggaaaca
    14581 tgatgagaga gcggtcactt tttttgagaa cgttgatagg atatttgatg gctgaggcgc
    14641 tgggattttc acggtcgatg ggaaaggcgc cacacatacg aatccaccaa ccaaagatac
    14701 ggttggtaaa gagttctttt tttgccataa agatgaactg ttttggcttg gtcgcaaagg
    14761 ccatataaac aggatcccac caggtacggt gaggcgcaac taaaatataa ttttcatctt
    14821 gattaggaat tttatcagta ttatgatagt gagcattgcc attgatggac cataagagca
    14881 atacaactaa tccacgcaaa taagtataaa acatgcgatc tccttcgatt gttttcttgt
    14941 tattattata ccttatcaaa ggagggctgg caaacttttc ccttgactag atgcatattt
    15001 gggatgaaat tagaattctg ttaaaaaaaa tgatataata gaatttatgg ataaaaataa
    15061 gattatggga ttaacccaaa gagaaatcaa ggaaagacag gctgagggtt tggtcaatga
    15121 ctttaccgca tcagccagta ccagcacttg gcaaatcgtt aaacgaaatg tctttaccct
    15181 ttttaacgct ttgaactttg ccattgcttt ggcccttgcc tttgtgcagg cttggagcaa
    15241 tctggtcttc tttgctgtta tctgctttaa cgctttttct gggattgtga ccgagctacg
    15301 agccaaacac atggtggaca agctcaatct catgaccaag gaaaaggtca aaaccatccg
    15361 tgatggtcag gaagttgctc ttaatcctga agaattagtg ctaggagatg tcattcgttt
    15421 gtctgcagga gagcagattc ctagtgatgc cttggttttg gaaggctttg cggaagtcaa
    15481 tgaagccatg ttaacgggag aaagtgattt ggtgcaaaag gaagttgacg gcttactttt
    15541 gtcaggaagt ttcctagcca gtgggtcagt tttatctcaa gttcaccatg tcggtgcaga
    15601 caactatgct gccaaactca tgcttgaggc taagaccgtt aaacccatca actcccgtat
    15661 catgaaatcg ctggacaagt tggctggttt tactgggaag attatcattc cctttggtct
    15721 ggctctcttg ctggaagcct tgcttttaaa aggcctgcct ctcaagtcat ccgttgtaaa
    15781 ctcgtcgaca gctcttttgg gaatgttgcc taagggaatt gcccttttga ccattacttc
    15841 gctcttgact gcagtgatta agttgggctt gaaaaaggtc ttggtgcagg agatgtactc
    15901 tgttgagacc ttggcgcgcg tggatatgct ctgtctggac aagacgggta ccatcaccca
    15961 aggaaagatg caggtggagg ctgttcttcc actgacggaa acttatggtg aagaggctgt
    16021 tgccagcatc ctgaccagct atatggccca tagtgaggat aaaaatccaa cagctcaagc
    16081 cattcgccag agattccaag gtcaagtagt ctatcctatg ctctctaatc ttcccttctc
    16141 cagcgaccgc aagtggggag ccatggagtt agaaggtttg ggaatagttt tcttaggggc
    16201 acctgagatg ttgctggatt ctgaggtccc agaagccaga gaggccttgg agagaggatc
    16261 acgtgtcttg gtcttagctc tcagtcagga gaaattagac catcacaaac cacagaaacc
    16321 atctgatatt caggctctag ccttgctgga aatcttggat cctattcgag agggagcggc
    16381 agagacgctg aactatctcc gttctcagga agtggggctc aagattatct ctggtgacaa
    16441 tccagttacg gtatccagca ttgcccagaa ggctggtttt gcggactatc acagctatgt
    16501 cgattgttca aaaatcacgg atgaggaatt gattgctctg gcggaggaga cagcgatttt
    16561 cggacgtgtt tcccctcatc aaaagaaact cattatccaa acgctgaaaa aagcgggtca
    16621 tacaacagct atgactgggg atggagttaa tgatatcctg gctcttcgtg aggcggattg
    16681 ttctatcgta atggcggagg gagacccggc aacccgtcag attgccaacc tggttctctt
    16741 gaactcagac tttaatgatg ttcctgagat tctttttgaa ggtcgtcgtg tggtcaataa
    16801 cattgcccac atcgctccga ttttcttgat aaagaccatc tattccttcc tgttagcagt
    16861 catctgtatt gccagtgctt tactaggtcg gtcagagtgg attttgattt tccccttcat
    16921 tccgatccag attaccatga ttgaccagtt tgtggaaggt ttcccaccat tcgttctgac
    16981 ttttgagcga aatatcaaac ctgttgagcc aaatttcctc agaaaatcca tgcttcgtgc
    17041 cctaccaagt gccctcatgg tcgtgtttag cgttcttttt gtgaaaatct ttggaacgag
    17101 tcaaggttgg tctgagttag aaatctcaac tctcctctat tatctcttgg ggtcaattgg
    17161 tttcttatcc gtatttagag cctgcatgcc attcactcta tggcgagtcc tcttgattgt
    17221 ctggtcagta ggaggcttcc tagccacagc tctcttccca agaatccaaa aactgcttga
    17281 aatttcaacc ttgacagaac aaacgttgcc tgtttatggt gtcatgatgt tggtctttac
    17341 agtgattttc atcctgacta gtcgctatca agctagaaaa taaagaaaga ctgcaatctg
    17401 tggattgcag tttttttagg tacaagattg ccagccgaaa tgtggtataa taagaggtaa
    17461 tagagttttg gaaagtgaga gaagatgatt tcaaagagat tagaattggt agcttccttt
    17521 gtgtcacagg gggctatttt actagatgtg ggaagtgacc atgcttatct gcctatcgag
    17581 ttggttgaga gaggccaaat caaaagcgct attgcaggtg aggtggtgga aggtccctat
    17641 cagtctgcgg ttaaaaatgt tgaggctcac ggcctaaagg agaaaatcca agtccgttta
    17701 gccaatggct tggcagcttt tgaagagact gaccaagtgt ctgtcattac cattgctggc
    17761 atgggtggtc gtttgattgc taggatttta gaagaaggtt tggggaagtt agctaatgta
    17821 gagcgtttga tcctccagcc caataatcgt gaagacgact tgcgtatctg gctacaggat
    17881 catggattcc agattgtagc agaaagcatc ttagaagaag ctggaaagtt ttatgagatt
    17941 ttggtggtgg aagcaggaca aatgaagcta tcagccagtg atgttcgctt tggtcccttc
    18001 ttgtccaaag aagtcagtcc agtatttgtc caaaaatggc aaaaagaagc tgagaagcta
    18061 gagttcgctc tcggacaaat cccagaaaaa aatctggaag aacgtcaagt tctagtagat
    18121 aagattcaag ctatcaagga ggtgctccat gttagcaagt gaagtgattc atgcttatga
    18181 agccttttgc cctcaggaat tttctatgga gggagacagc cgtggtctgc aaattggcac
    18241 tttagacaag ggtatccaaa gggtcatggt tgccctcgat attcgtgaag agacagtggc
    18301 agaggccatt gaaaagggtg tggacttgat tatcgtcaag cacgcgccta tctttcgtcc
    18361 tatcaaggac ttgcttgcca gccgtccgca aaatcagatt tacatcgacc tgattaagca
    18421 tgacatcgca gtttatgtca gccataccaa tattgatatc gttgaaaatg ggctcaatga
    18481 ctggttttgt cagatgctag gaatcgagga gacgacttat ctgcaggaaa caggtccaga
    18541 acgtggaatt ggacgtattg ggaatattca gcctcagaca ttttgggaat tggcccaaca
    18601 ggtcaagcaa gtctttgacc tagatagcct tcgaatggtg cattatcaag agaatgattt
    18661 gcagaagcct atttcaagag tagcaatttg tggtggaagc gggcagtctt tctataagga
    18721 tgctttggca aagggggcag atgtctatat cactggtgat atctactacc atactgctca
    18781 ggatatgctg tctgatggct tgttagcatt ggatccaggt cactatatcg aagtgctttt
    18841 tgtggaaaaa atcgcagcac tccttactca atggaaagag aaaaaaggct gggaactaga
    18901 gattttacct agtcaagcat cgaccaatcc tttccgtcat atctagttag aaagtgaaga
    18961 caatgaaaaa agttgccatt attggagcag gaattgtggg agcaacagct gcctactacc
    19021 tctcgagaga aagtgaccta gaggtgaccg tttttgacca tgagcaaggt caagccacca
    19081 aggccgcagc aggaattatc agtccttggt tttccaaacg ccgtaataaa gcctggtaca
    19141 agatggcgcg cttgggggct gatttttatg tggatttatt agctgattta gagaaatcag
    19201 gacaaaaaat cgacttttac cagcgttcgg gagtctttct cttgaaaaag gatgaatcca
    19261 agttggaaga actttatcaa ctggccctcc agcgcagaga agaatctccc ttgatagggc
    19321 aattagccat tctggaccaa gcctcagcta atgaattatt ccctggtttg cagggatttg
    19381 accgcctgct ctatgcttct ggtggagcga gagtagatgg ccaactcttg gtaactcgtc
    19441 tgctagaagc cagtcatgtc aagctggtca aagaaaaagt gactctgaca ccgttagcat
    19501 caggctacca gattggtgaa gaggagtttg agcaggttat tttggcgacg ggagcttggt
    19561 tgggggacat gttagaaccc ttgggttatg aagtagatgt tcgtcctcaa aaaggacaac
    19621 tacgagatta tcagctggtc caagacatgg aagcttaccc tgttgtcatg ccagaagggg
    19681 agtgggattt gattcctttt gcaggtggga aattgtcctt aggcgctacc cacgaaaatg
    19741 acatgggatt tgatttgacg gtagatgaaa ccttgctcca acaaatggag gaggccacct
    19801 tgactcacta tctgattttg gctgaagcta cttcaaaatc tgagcgtgtt ggaatccgtg
    19861 cctacaccag tgatttctct cctttctttg ggcaggtgcc tgacttaact ggtgtctatg
    19921 cagccagtgg actaggttca tcaggcctca caactggtcc tattattggt taccatttag
    19981 ctcaactgat ccaagacaag gagttgacct tggaccctga aaactaccca attgaaaact
    20041 atgtcaaacg agtaaaaagc gaataatact caatgaaaat caaagaacaa actaggaaac
    20101 tagccgcggg ttactcaaag cactgctttg aggttgtgga tagaactgac gaagtcagct
    20161 caaaacactg ttttgaggtt gtagatagaa ctgacgaagt cagtaaccat acccatggca
    20221 aggcgacgtt gacgtggttt gaattggatt ttcgaagagt ataagcattt tactgaaatt
    20281 ttatcaggta gtttaggatg gcaaatgaca ttccctgtca aaaatggtaa aataagaaaa
    20341 aataatctga gaatcgagga aaaaagatgc aagaaaagat tttggtaact ggtggtgccg
    20401 gttttattgg aacccacact gttattgaat tgatccaagc aggccatcaa gttgttgtgg
    20461 tggataatct tgtcaatagc aatcgtaaga gtttagaagt tgttgaaaga atcacaggag
    20521 ttgagattcc tttctatgag gcagatattc gtgacacagc taccctcaga gatattttca
    20581 agcaggaaga accgactggt gtcattcact ttgctggttt gaaggctgtt ggcgaatcaa
    20641 cacgtatccc tcttgcctac tatgacaaca atatcgctgg aactgtcagc cttttgaaag
    20701 ccatagaaga aaacaactgt aaaaacatca tcttcagttc ttctgcgaca gtttacgggg
    20761 atccgcacac agtgcccatc ttggaagatt tcccactttc agtgaccaac ccatacggtc
    20821 gtactaagct catgctagag gaaattttga ctgatattta caaagcagac tcagaatgga
    20881 atgttgtctt gcttcgttac tttaacccaa tcggagccca tgagagtggt gatttgggag
    20941 aaaatccaaa cggtattcca aacaatctct tgccatatgt gactcaagta gccgttggaa
    21001 aattagagca agtgcaagtg tttggagacg attacgatac ggaagatgga acaggtgttc
    21061 gtgactatat ccacgttgtc gatttggcta agggtcacgt tgcagctttg aaaaaaatcc
    21121 aaaaaggttc aggactaaac gtttataacc ttggaactgg taaaggttac tcagttcttg
    21181 aaattatcca aaacatggaa aaagcggtgg gacgtcctat tccttaccgt atcgtagaac
    21241 gtcgcccagg tgatatcgct gcctgctact cagacccagc aaaagctaaa gcagaactcg
    21301 gttgggaagc agaactcgac atcacccaaa tgtgtgaaga cgcatggcgt tggcaaagca
    21361 agcatccaaa tggatttgaa gactaagatg atgatttcaa tcatcgtccc ttgtttaaac
    21421 gaagaggaag tacttcctct tttttatcag gctctggaag ctttacttcc agatttggaa
    21481 acagaaatcg agtatgtctt tgtcgatgat ggatcaagtg atgggacctt ggaactctta
    21541 aaggcctatc gggagcaaaa tccggcagtc cattatattt ctttctctcg aaattttggc
    21601 aaagaagcag ccctttatgc aggcttgcaa tatgcgacag gagatttggt ggtggtgatg
    21661 gatgcagacc tccaagatcc tcctagtatg ttgtttgaga tgaaaaatgt actagacaaa
    21721 aatgtagact tggactgcgt tgggacacgg agaactagtc gggagggaga acccttcttt
    21781 cgcagtttct gtgctgttct cttttatcgc ctcatgcaaa aaatcagccc agtggctctg
    21841 ccgtcgggtg tccgtgattt tcgtatgatg agaaggtctg tagtcgatgc cattttaagc
    21901 ttgaccgagt ccaatcgttt ttcaaagggg ctcttcgcct gggtgggttt caaaacctac
    21961 tatttggact atccaaatgt cgaaaggcag gctggcaaga ccagttggag ttttaggaaa
    22021 ctctttttct actccattga agggattatt aatttttcag attttccctt gattatagcc
    22081 tttgtagctg gtctcctatc ttgttttctt tctctgctga tgaccttttt tgttgtggtt
    22141 cggaccctca ttttgggcaa tccgacatct ggttggacct ctctgatggc tgttattctc
    22201 tttcttggag gcattcaact cttgaccatt gggattctcg gcaagtatat cagtaagatt
    22261 tatttagaga ctaaaaaaag accactttat cttatcaaag aaaaaagtga tgataggcta
    22321 aaaaagatag aatttatctg acatagtcac tttttgttat ttgtaattct tttagttcgg
    22381 agtttgggtg atttttaaaa gaattaggga tttgaaatga tttaaaaaat ctatgtagac
    22441 taaatttaaa ttgtagtgac ttaataaata aaaaatttag gagtattatg ttatgctaag
    22501 taaagaggat tatactgaag aaatcgggct aataaagaaa caaaattatg tagaggctga
    22561 attgtatcct atagttgctg atataattaa gccaacttta aaagatagtt tatcaaaaag
    22621 atatgtcttc ggaagacaaa gaaggggttt gggacaaatt tattatggtc taagtaattt
    22681 tcctgatata gttattttag ataagactta tgaaaacaaa tctaggaaaa gtataaaaat
    22741 tgaagaatgg aagaaacttc gaggatgcgt ggaagttaag aatttaaatt atagtttaat
    22801 tacagaggaa aaaatcaaat caaccatatc gaacagtttt gaacatataa ctggagagat
    22861 ggaacaacta actggagaga tgggacaact tattggagac cttttatggt ataaaaaagt
    22921 aatttataca aatggaattg aatggagatt tctaagttta gatgacaagg aagagataga
    22981 taatacaatt gttgaagtag ttaacaaaag aatagaaaca gaagaagcgg gaaattcttt
    23041 tgattggtgg aagaatatta aagatttatc gttcaattat acggatatat gcctatctaa
    23101 agattgtaga caagagtgga atgaatttgt aaaaagggta aaggaaatag aatggtagaa
    23161 gtctattctc attgagaaat ttagatttta agttacagta agatttattt agagactaaa
    23221 aaaagaccac tttatcttat caaagaaaaa agtgaccttc ctgattttac agaaaaaaat
    23281 aaagtgaaaa gactataatt ttacatggaa atgtgctaaa ctagagggag tggattatcg
    23341 ccattgattt aggcttcctg gtttccaatc agggcgcgag ttgggcaatt tttaacagcc
    23401 tctaagacat cctgactagg agaaatttct ttttccagtt ggtcagggtc atcgtaaaaa
    23461 cgcacgattc cattatcgtg gtaatcaaat aaatcagaat aagtttggca aagcccacag
    23521 gcgatacatc gttcaggtat aagtgtgatt ttcatgttca tatttatatt gtaataagaa
    23581 aagtaaaaaa aaacaaggag taaggtatgg caaaagaacc gtggcaagaa gatatctatg
    23641 atcaagaaga atcaagagca gagcgtcggc atcgaaacca cggaggggct gataggatgg
    23701 ctaatcgtat tttgacgatc ctagctagta ttttctttgt aattgtggtg gtgatggtca
    23761 tcgttctcat ctatctatca tcggggggaa gtaatcgcac agcagcctta aaagactttc
    23821 atgattctga tgcaagtgta gtacaaatct catcttcaag cagttctcag cctgagcaga
    23881 gttcagagcc agaatctact tctagtagtt cagaagaagc tgctaatcct gaaggaacga
    23941 ttaaagttct cgcaggagaa ggggaagcag ctattgccgc tcgtgcagga atctccattg
    24001 ctcagttaga ggccttgaat cctgggcaca tggctacagg atcttggttt gctaatccag
    24061 gtgatgttat aaaaataaaa taggagccga tatgaaaaca attcaaattg ctattgatgg
    24121 tcctgcttcc agcggtaaga gtacggtcgc aaagattatt gctaaggatt ttggattcac
    24181 ctaccttgat acaggagcta tgtatcgtgc agcgacctat atggctctta agaaccaatt
    24241 aggagttgaa gaagtcgaag cccttctagc cttgttggac cagcatccaa tcagctttgg
    24301 acgttcagaa actggagacc agcttgtttt tgtaggagat gtggatatta cccatcctat
    24361 ccgtgaaaat gaagtgacca atcatgtttc tgctattgca gcaattcctg aagtgcgtga
    24421 gaaactggtt tctctccaac aagaaattgc ccagcaaggc gggattgtca tggatggtcg
    24481 cgatattgga actgttgtat tgccacaagc agaattgaaa attttcctag tagcttctgt
    24541 tgatgagaga gcagagcgtc gttacaagga aaatattgcc aagggaattg aaacagactt
    24601 tgaaacccta aaaaaggaaa ttgctgcgcg tgactacaag gatagtcatc gtgagacttc
    24661 tcctctcaaa caagcagagg atgctgtcta ccttgataca actggtttga acattcaaga
    24721 agtagttgaa aaaatcaaag cagaagctga aaaaagaatg taaatgtaga aaagccgata
    24781 gattgatatc ggtttttttc taaatttgtc aaaatgctga ttttagggta taatagttgc
    24841 tgttcgagaa attttgattt tcaaagaata gtgaatgatg ataaggagaa accatgaaca
    24901 atttaccaaa ttgtccaaaa tgtaactcag agtatgtcta cgaagacggt gccctactgg
    24961 tttgcccaga gtgtgctcat gagtggaatc ctgctgaagt tgcagaagta gaagaaggtc
    25021 ttgtcgctat cgatgccaac ggaaataaat tggctgatgg tgatacagta actctcatca
    25081 aggacttgaa agtaaaaggt gcgccaaaag atttgaaaca agggacgcgc gtgaaaaata
    25141 tccgcatcgt agaaggcgac cacaatatcg actgtaagat tgatggtttt ggtgccatga
    25201 aacttaaatc agagtttgtg aggaagattt aagcatgtca aaacactata aacttgtatt
    25261 ttatagccgt atcttcttgt ttctagcggc ttttacggga gtttatcttg aaattactaa
    25321 gcatggtggt tttgggatgc ttctctatta cacggttctg tccaacctct tggtaactat
    25381 ttttaccctt tatcttctaa aggttatgag ccgtgtaggt gaaaattggc aaaggccaag
    25441 tctcttgcgc ttaaaaggtg gggtcaccat gagtatcatg attacctgtg tgatttacca
    25501 tttcctcttg gcgcccattg cgactaattt ctatacccta gaaaatttcc tttgccacta
    25561 tatcgttccc atctggtttt tagcggatac cctctttttt gacaaacagg gtcaatacaa
    25621 gatttgggat ccagcagtgt ggaccatttt accctttctg tatatgatgt ttgctctttt
    25681 taatggcttg gttctaaaac tcaatattcc aaatgccaag gataatcctt tcccttactt
    25741 ctttttgaat gtgaacaagg gttggaatgt tgtgtttaag tggtgtctga ttatctttgt
    25801 tgcctatatg gtagcaggat ttattttcta ctttatcaag caaatcaaga gaaagtcatc
    25861 ctaatactct tcgaaaatct cttcaaacca cgtcagtttc catctgcaac ctcaaaacac
    25921 tgttttgaac aacctgcggc tagcttccta gtttgctctt tgattttcat tgagtataag
    25981 atacaaggga ttcattttcg aatttaagaa ggagtctaca aaccaatgag gcttcttctt
    26041 ttcttgctta tttgataact atcaaaaaag tagaagatta agagaaatat agaaagagat
    26101 ttcatgaaac aatttttaga acgggccagc attttggctc tctccctcgt tttgattacc
    26161 tccttttcca tttcgagtgc cctaccagcc atgtttgact attatcaggg ttattctaag
    26221 gaacaaattg agctcttggt gagcttgcct tcctttggaa tcatgatgat gttactgcta
    26281 aatggtttct tagaaaaaat atttcctgag cgcttacaga ttagtttggg cttgctgatt
    26341 ttatcattga gcggtacagc tcccttctgg taccaagcct atccctttgt ctttggaaca
    26401 cggcttctct ttggtttggg tcttgggatg atcaatgcca aggccatttc tattatcagt
    26461 gaacgctacc aaggaaaaag gcgaattcag atgttagggc tacgcgcttc tgcagaggtc
    26521 gttggagctt ctctcattac cttggccgtc ggtcagttgt tggcctttgg ttggacagct
    26581 atctttctag cctatagtgc tggatttttg gtgctgcccc tttatctgct ctttgtccct
    26641 tatggaaaat caaagaaaga agtcaagaaa agagcgaagg aagcaagtcg tttaactcga
    26701 gaaatgaaag gcttgatttt taccttagct atcgaagcgg cagttgtagt ttgtaccaat
    26761 acagctatta ccatccgtat tccaagtttg atggtggaaa gaggattggg ggatgcccag
    26821 ttatctagtt ttgttcttag tatcatgcag ttgatcggga ttgtggctgg ggtgagtttt
    26881 tctttcttga tttctatctt taaagagaaa ctgctcctct ggtctggtat tacctttggc
    26941 ttggggcaaa tcgtgattgc cttgtcttca tccttgtggg tggtagtagc aggaagtgtt
    27001 ctggctggat ttgcctatag tgtagtcttg acgacggtct ttcaacttgt ctctgaacga
    27061 attccagcta aactcctcaa tcaagcaact tcatttgctg tattaggctg tagtttcgga
    27121 gcctttacga ccccatttgt tctaggtgca attggcttac taactcacaa tgggatgttg
    27181 gtctttagta tcttaggagg ttggttgatt gtaatctcta tctttgtcat gtacctactt
    27241 cagaagagag cttaggattg attcctaagt ttttcttttg atactcaatg aaaatcaaag
    27301 agcatagttg attgagtttg gaatagtacg ctgtagctgc taaaatattt ctagaaatta
    27361 atttgacttt tctaatagag ttattcatat cttatttcaa tctactatag aaagctagcc
    27421 gcaggttgct caaaatagtg ttttgaggtt gcagatggaa actgacgtgg tttgaagaga
    27481 ttttcgaaga gtatgagatt tttataccca tacaatattt gttttaggtc cttgtttaca
    27541 gactaatttc ttgataaaat agaggttatg acgagatata aagcaactat ttcctatgat
    27601 ggttatgcct ttgctggctt tcagcgccag cctcatgcgc gtagcgttca ggaagaaatt
    27661 gaaaaaacct tgaccagatt aaataaaggg caagccatta ctgttcacgg tgctggtagg
    27721 acagatagtg gggttcatgc cctgggacag gtcattcatt ttgacctgcc ttatcagatg
    27781 gatgaggaga aactccgttt tgccttggat acccagtctc ctgaagatat tgatgtgatt
    27841 tcgattgagc ttgtggcaga tgattttcat tgccgttatg ccaagcatag caagacctat
    27901 gagtttactg tggatagagg acgtcccaaa aatccgatgc gccgtcacta tgccacccac
    27961 tttccctacc cactcgatgt ggaacgaatg cagattgcaa tcaaaaagct agagggaacc
    28021 catgatttta ccggttttac agcctctggg actagtgtag aggataaggt tcgcaccatc
    28081 acagaagcta gtttaatagt cgatgagaca ggacaatttt tgacctttac cttttcagga
    28141 aatggtttct tgtataaaca gattcgcaat atggtgggga ctcttctcaa aatcggtaac
    28201 aaccgcatgc cagtagagca gattgatctc atcttggaga agaaggacag gcaacttgca
    28261 ggtcccactg cagcaccaaa tggtttgtat ttaaaggaga ttcgttatga agaataatcg
    28321 tattttagca ctttctggaa atgatatttt tagtggtggt ggactgtcag ctgatttggc
    28381 tacctatacc ttgaacggct tgcatgggtt tgtagcagtg acttgtttga cagccttgac
    28441 agaaaaagga tttgaagtct ttccaactga tgataccatt tttcaacatg aattagatag
    28501 cttgcgtgat gtggaatttg ggggaattaa gattggtctt ctccctactg tcagtgtggc
    28561 tgagaaggcc ttggacttta tcaaacaacg cccaggagta cctgtggtgt tggatcctgt
    28621 cttggtctgc aaggaaacgc atgatgtagc tgtcagtgag ctctgccaag agttgattcg
    28681 ctttttccct tatgtcagtg tgattacgcc taatctccca gaagcagaat tattatccgg
    28741 tcaggaaatt aaaaccttgg aagacatgaa aactgcagcg cagaaattgc atgatttagg
    28801 agcgccagca gtcattatca agggaggcaa tcgtcttagt caggacaagg ctgtggatgt
    28861 cttttatgat ggacagacct ttactatcct agaaaatcca gttatccaag gccaaaatgc
    28921 tggtgcaggt tgtacctttg cctctagcat tgccagtcac ttgattaaag gtgataaact
    28981 tttgccagca gtagaaagct ctaaggcttt cgtttatcgt gctattgcac aagcagatca
    29041 gtatggagta agacaatatg aagcaaacaa aaacaactaa aatcgccctt gtatccctat
    29101 taaccgccct ttctgtggtt ctaggttatt tcttaaaaat cccaacacct acaggaattc
    29161 taactctttt agatgctggt gtcttctttg cggcctttta ctttggtagt cgtgaaggag
    29221 cggtagtcgg aggactagca agtttcttga ttgacctctt atcaggctac cctcagtgga
    29281 tgttctttag cttggtcaac catggcttgc agggattttt cgcaggattt aaaggaaaaa
    29341 gtcagtggtt aggccttatt ttagcaacta ttgccatggt aggaggctac gccttgggtt
    29401 ctactttgat gaatggctgg gcagcagccc tcccagaaat tctaccaaat ttcatgcaaa
    29461 atatggtagg gatgattgta ggatttattc ttagtcaaag tatcaagaag attaagtaat
    29521 actcttcgaa aatctcttca aaccacgtca gcttccatct gcaacctcaa aacactgttt
    29581 tgagcagcct gaggctagct ttctagtttg cactttgatt ttcattgagt ataaagaggt
    29641 tgagtaaaaa gtatttcaaa taagaaaaac gcatagtatc aggtgttgaa tgaactgccc
    29701 cccaaaaagt tagacagaaa aaatctaact ttttggggtg tttttattat gaaattaa
//
LOCUS       DAVBBO010000024        28764 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ST1
            SAMEA2066453-rid20184263.denovo.024, whole genome shotgun sequence.
ACCESSION   DAVBBO010000024 DAVBBO010000000
VERSION     DAVBBO010000024.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2066453
            Sequence Read Archive: ERR351777
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 28764)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 28764)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980402.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980402.1
            Genome Coverage       :: 176x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:17:33
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,141
            CDSs (total)                      :: 2,104
            Genes (coding)                    :: 1,953
            CDSs (with protein)               :: 1,953
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 16S)
            partial rRNAs                     :: 1 (23S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 151
            CDSs (without protein)            :: 151
            Pseudo Genes (ambiguous residues) :: 0 of 151
            Pseudo Genes (frameshifted)       :: 73 of 151
            Pseudo Genes (incomplete)         :: 76 of 151
            Pseudo Genes (internal stop)      :: 40 of 151
            Pseudo Genes (multiple problems)  :: 32 of 151
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..28764
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2066453-rid20184263.denovo.024"
                     /strain="ST1"
                     /db_xref="taxon:1313"
     gene            complement(7..387)
                     /locus_tag="VQU30_001050"
                     /pseudo
     CDS             complement(7..387)
                     /locus_tag="VQU30_001050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase family protein"
     gene            733..1686
                     /locus_tag="VQU30_001051"
     CDS             733..1686
                     /locus_tag="VQU30_001051"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000345081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HET2447172.1"
                     /translation="MDFEKIEQAYTYLLENVQVIQSDLATNFYDALVEQNSIYLDGET
                     ELNQVKDNNQALKRLALRKEEWLKTYQFLLMKAGQTEPLQANHQFTPDAIALLLVFIV
                     EELFKEEEITILEMGSGMGILGATFLISLDKKVDYLGMEVDDLLIDLAASMADVIGLQ
                     AGFVQGDAVRPQMLKESDVVISDLPVGYYPDDAVASRHQVASSQEHTYAHHLLMEQGL
                     KYLKSDGYAIFLAPSDLLTSPQSDLLKEWLKEEASLVAMISLPENLFANAKQSKTIFI
                     LQKKSEIAVEPFVYPLASLQDASVLMKFKENFQKWTQGTEI"
     gene            1737..2927
                     /locus_tag="VQU30_001052"
     CDS             1737..2927
                     /locus_tag="VQU30_001052"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000167779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetate kinase"
                     /protein_id="HET2447173.1"
                     /translation="MTKTIAINAGSSSLKWQLYLMPEEKVLAKGLIERIGLKDSISTV
                     KFDGRSEQQILDIENHTQAVKILLDDLIRFDIIKAYDEITGVGHRVVAGGEYFKESTV
                     VEGDVLEKVEELSLLAPLHNPANAAGVRAFKELLPDITSVVVFDTSFHTSMPEKAYRY
                     PLPTKYYTENKVRKYGAHGTSHQFVAGEAAKLLGRPLEDLKLITCHIGNGGSITAVKA
                     GKSVDTSMGFTPLGGIMMGTRTGDIDPAIIPYLMQYTEDFNTPEDISRVLNRESGLLG
                     VSANSSDMRDIEAAVAEGNHEASLAYEMYVDRIQKHIGQYLAVLNGTDAIVFTAGVGE
                     NAENFRRDVISGISWFGCDVDDEKNVFGVTGDISTEAAKIRVLVIPTDEELVIARDVE
                     RLKK"
     gene            3076..3447
                     /gene="rnpA"
                     /locus_tag="VQU30_001053"
     CDS             3076..3447
                     /gene="rnpA"
                     /locus_tag="VQU30_001053"
                     /EC_number="3.1.26.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000739244.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease P protein component"
                     /protein_id="HET2447174.1"
                     /translation="MKKNFRVKREKDFKAIFKEGTSFANRKFVVYQLENQKNHFRVGL
                     SVSKKLGNAVTRNQIKRRIRHIIQNAKGSLVEDVDFVVIARKGVETLGYAEMEKNLLH
                     VLKLSKIYREGNGSEKETKVD"
     gene            3422..4246
                     /locus_tag="VQU30_001054"
     CDS             3422..4246
                     /locus_tag="VQU30_001054"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000727905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein insertase YidC"
                     /protein_id="HET2447175.1"
                     /translation="MKKKLKLTSLLGLSLLIMTACATNGVTSDITAESADFWSKLVYF
                     FAKIIRFLSFDISIGVGIILFTVLIRTVLLPVFQVQMVASRKMQEAQPRIKALREQYP
                     GRDMESRTKLEQEMRKVFKEMGVRQSDSLWPILIQMPVILALFQALSRVDFLKTGHFL
                     WINLGSVDTTLVLPILAAVFTFLSTWLSNKALSERNGATTAMMYGIPVLIFIFAVYAP
                     GGVALYWTVSNAYQVLQTYFLNNPFKIIAEREAVVQAQKDLENRKRKAKKKAQKTK"
     gene            4265..5251
                     /locus_tag="VQU30_001055"
     CDS             4265..5251
                     /locus_tag="VQU30_001055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398435.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein jag"
                     /protein_id="HET2447176.1"
                     /translation="MVVFTGSTVEEAIQKGLKELDIPRMKAHIKVISREKKGFLGLFG
                     KKPAQVDIEAISETTVVKANQQVVKGVPKKINDLNEPVKTVSEETVDLGHVVDAIKKI
                     EEEGQGISDEVKAEILKHERHASTILEETGHIEILNELQIEEAMREEAGADDLETEQD
                     QTENQDLKEMGLKVEQSYDIAQVATDVTAYVQAIVDDMDVEATLSNDYNRRSINLQID
                     TNEPGRIIGYHGKVLKALQLLAQNYLYNRYSKTFYVTINVNDYVEHRAEVLQTYAQKL
                     AIRVLEEGRSHQTDPMSNSERKIIHRIISRMDGVTSYSEGDEPNRYVVVDTE"
     gene            5302..5925
                     /locus_tag="VQU30_001056"
     CDS             5302..5925
                     /locus_tag="VQU30_001056"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000932659.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease P"
                     /protein_id="HET2447177.1"
                     /translation="MLNKIRDYLDFAGLQYRNPDKAGAEREKMLAFRHKGQEARKAFT
                     ELAKAFQASHPGWQLQQTSQWMNQAQRLRPHFWVYLQRDEQVTEPMMALRLYGTSTDF
                     GISLEVSFIERKKDEQTLGKQAKVLDIPTVKGIYYLTYSNGQSQRWEANEEKRRTLRE
                     KVRSQEVRKVLVKVDVPMTENSSEEEIVEGLLKSYSKILPYYLATRK"
     gene            6056..7513
                     /locus_tag="VQU30_001057"
     CDS             6056..7513
                     /locus_tag="VQU30_001057"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006153412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS ascorbate transporter subunit IIC"
                     /protein_id="HET2447178.1"
                     /translation="MEVVSSVLNWFSSNILQNPAFFVGLLVLIGYALLKKPAHDVFSG
                     FVKATVGYMLLNVGAGGLVTTFRPILAALNYKFQIGAAVIDPYFGLAAANNKIAAEFP
                     DFVGTATTALLIGFGINILLVALRKITKVRTLFITGHIMVQQAATVSLMVLFLVPQLR
                     NAYGTAAIGIICGLYWAVSSNMTVEATQRLTGGGGFAIGHQQQFAIWFVDKVAGRFGK
                     KEESLDNLKLPKFLSIFHDTVVASATLMLVFFGAILLILGPDIMSNKEVITSGTLFNP
                     AKQDFFMYIIQTAFTFSVYLFVLMQGVRMFVSELTNAFQGISNKLLPGSFPAVDVAAS
                     YGFGSPNAVLSGFTFGLIGQLITIVLLIVFKNPILIITGFVPVFFDNAAIAVYADKRG
                     GWKAAVILSFISGVLQVALGALCVALLDLASYGGYHGNIDFEFPWLGFGYIFKYLGIV
                     GYVLVCLFLLVIPQLQFAKAKDKEKYYNGEVQEEA"
     gene            7536..7817
                     /locus_tag="VQU30_001058"
     CDS             7536..7817
                     /locus_tag="VQU30_001058"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000241469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HET2447179.1"
                     /translation="MVKVLAACGNGMGSSMVIKMKVENALRKLNQTDFTVNSCSVGEA
                     KGLAVGYDIVIASLHLIQELEGRTNGKLIGLDNLMDDKEITEKLSQALQ"
     gene            7894..8379
                     /locus_tag="VQU30_001059"
     CDS             7894..8379
                     /locus_tag="VQU30_001059"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HET2447180.1"
                     /translation="MNLKQALIDNDSIRLGLEANNWKEAVKVAVDPLIESGAILPEYY
                     DAIIESTEEYGPYYILMPGMAMPHARPEAGVQSDAFSLITLQNPVVFSDGKEVSVLLA
                     LAATSSKIHTSVAIPQIIALFELEDSIARLQACQTKEDVLAMIEESKDSPYLEGLDLE
                     S"
     gene            8396..9061
                     /locus_tag="VQU30_001060"
     CDS             8396..9061
                     /locus_tag="VQU30_001060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000166733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-keto-L-gulonate-6-phosphate decarboxylase
                     UlaD"
                     /protein_id="HET2447181.1"
                     /translation="MTKRIPNLQVALDHSDLQGAIKAAVSVGQEVDIIEAGTVCLLQV
                     GSELAEVLRSLFPDKIIVADTKCADAGGTVAKNNAVRGADWMTCICCATIPTMEAALK
                     AIKTERGERGEIQIELYGDWTFEQAQLWLDAGISQAIYHQSRDALLAGETWGEKDLNK
                     VKKLIDMGFRVSVTGGLDVDTLKLFEGVDVFTFIAGRGITEAADPAGAARAFKDEIKR
                     IWG"
     gene            9065..9928
                     /locus_tag="VQU30_001061"
     CDS             9065..9928
                     /locus_tag="VQU30_001061"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000252119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-ribulose-5-phosphate 3-epimerase"
                     /protein_id="HET2447182.1"
                     /translation="MVRPIGIYEKATPTHFTWLERLNFAKELGFDFVEMSIDERDERL
                     ARLDWSKEERLEVVKEIYETGVRIPSICFSGHRRYPLGSKDPVLEEKSLELMKKCIEL
                     AQDLGVRTIQLAGYDVYYEEKSPQTRQRFIKNLRKACDWAEEAQVVLAIEIMDDPFIN
                     SIEKYLAIEKEIDSPFLFVYPDIGNVSAWHNDIYSEFYLGHHAIAALHLKDTYAVTES
                     SRGQFRDVPFGQGCVKWEEAFDILKETNYNGPFLIEMWSENCETVEETRAAIQEAQAF
                     LYPLIKKAGLM"
     gene            9930..10634
                     /locus_tag="VQU30_001062"
     CDS             9930..10634
                     /locus_tag="VQU30_001062"
                     /EC_number="5.1.3.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001077552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-ribulose-5-phosphate 4-epimerase"
                     /protein_id="HET2447183.1"
                     /translation="MNQVINAMRKRVCDANQSLPKHGLVKFTWGNVSEVNRELGVIVI
                     KPSGVDYDELTPENMVVTDLDGKILEGDLRPSSDLPTHVQLYKAWSEIGSVVHTHSTE
                     AVAWAQAGRDIPFYGTTHADYFYGSIPCARSLTKDEVEVAYEKDTGLVIVEEFEHRGL
                     NPVEVPGIVVRNHGPFTWGKNPENAVYHSVVLEEVSKMNRFTEQINPRVGPAPQYILE
                     KHYQRKHGPNAYYGQK"
     gene            10813..12486
                     /locus_tag="VQU30_001063"
     CDS             10813..12486
                     /locus_tag="VQU30_001063"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antiterminator"
                     /protein_id="HET2447184.1"
                     /translation="MVLDKASCDLLQYLMDQETSKTIMAISKDLKESRRKIYYHIDKI
                     NAALGDEALHIISIPRIGIHLTEEQRDACCKLLSEVDSYDYIMSAHERMMIMLLWIGI
                     SKERITIEKLIELTEVSRNTVLNDLNSIRYQLTLEQYQVILQVSKSQGYHLHAHPLNK
                     IQYLQSLLYHIFMEENATFVSILEDKMKERLDDECLLSVEMNQFFKEQVPLVEQDLGK
                     KINHHEITFMLQVLPYLLLSCHNVEQYQERHQDIEKEFSLIRKRIEYQVSKKLGERLF
                     QKFEISLSGLEVSLVAVLLLSYRKDLDIHAESDDFRQLKLALEEFIWYFESQIRMEIE
                     NKDDLLRNLMIHCKALLFRKTYGIFSKNPLTKQIRSKYGELFLVTRKSAEILEGAWFI
                     RLTDDDIAYLTIHIGGFLKYTPSSQKNMKKVYLVCDEGVAVSRLLLKQCKLYFPNEQI
                     DTVFTTEQFKSVEDIAQVDVVITTNDDLDSRFPILRVNPILEAEDILKMLDYLKHNIF
                     RNKSKSFSENLSSLISSYIVDSKLASKFQEEVQTLINQEIVVQAFLEDI"
     gene            12598..13689
                     /gene="ulaG"
                     /locus_tag="VQU30_001064"
     CDS             12598..13689
                     /gene="ulaG"
                     /locus_tag="VQU30_001064"
                     /EC_number="3.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-ascorbate 6-phosphate lactonase"
                     /protein_id="HET2447185.1"
                     /translation="MPNVKEITRESWILATFPEWGTWLNEEIEEEVVPEGNFAMWWLG
                     NCGTWIKTPAGANVVMDLWSNRGKSTKKVKDMVRGHQMANMAGVRKLQPNLRVQPMVI
                     DPFAINELDYYLVSHFHSDHIDPYTAAAILNNPKLEHVKFIGPYHCGRIWEGWGVPKE
                     RIIVVKPGDTIELKDMKIHAVESFDRTCLVTLPVNGADETGGELAGLAVTDEEMAQKA
                     VNYIFETPGGTIYHGADSHFSNYFAKHGKDFKIDVALNNYGENPVGIQDKMTSIDLLR
                     MAENLRTKVIIPVHYDIWSNFMASTNEILELWKMRKDRLQYDFHPFIWEVGGKYTYPQ
                     DQHLVEYHHPRGFDDCFEQDSNIQFKALL"
     gene            13803..15779
                     /gene="tkt"
                     /locus_tag="VQU30_001065"
     CDS             13803..15779
                     /gene="tkt"
                     /locus_tag="VQU30_001065"
                     /EC_number="2.2.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004185329.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transketolase"
                     /protein_id="HET2447186.1"
                     /translation="MSNLSVNAIRFLGIDAINKANSGHPGVVMGAAPMAYSLFTKQLH
                     INPAQPNWINRDRFILSAGHGSMLLYALLHLSGFEDVSMDEIKSFRQWGSKTPGHPEF
                     GHTAGIDATTGPLGQGISTATGFAQAERFLAAKYNREGYNIFDHYTYVICGDGDLMEG
                     VSSEAASYAGLQKLDKLVVLYDSNDINLDGETKDSFTESVRDRYNAYGWHTALVENGT
                     DLEAIHAAIETAKASGKPSLIEVKTVIGYGSPNKQGTNAVHGAPLGADETASTRQALG
                     WDYEPFEIPEQVYADFKEHVADRGASAYQAWTKLVTDYKEAHPELAAEVEAIIDGRDP
                     VEVTPADFPALENGFSQATRNSSQDALNVVAAKLPTFLGGSADLAHSNMTYIKTDGLQ
                     DDANRLNRNIQFGVREFAMGTILNGMALHGGLRVYGGTFFVFSDYVKAAVRLSALQGL
                     PVTYVFTHDSIAVGEDGPTHEPVEHLAGLRAMPNLNVFRPADARETQAAWYLAVTSEK
                     TPTALVLTRQNLTVEDGTDFDKVAKGAYVVYENAADFDTILIATGSEVNLAVSAAKEL
                     ASQGEKIRVVSMPSTDVFDKQDAAYKEEILPNAVRRRVAVEMGASQNWYKYVGLDGAV
                     LGIDTFGASAPAPKVLAEYGFTVENLVKVVRNLK"
     gene            15896..16195
                     /gene="yajC"
                     /locus_tag="VQU30_001066"
     CDS             15896..16195
                     /gene="yajC"
                     /locus_tag="VQU30_001066"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001069053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit YajC"
                     /protein_id="HET2447187.1"
                     /translation="MNPNITFLIMLVGMMALMFFMQRSQKKQAQKRMESLNKLQKGYE
                     VITIGGLYGTVDEVDTEKGTIVLDVEGVYLTFELAAIKTVLPLKETASLEGAIEK"
     gene            16242..16670
                     /locus_tag="VQU30_001067"
     CDS             16242..16670
                     /locus_tag="VQU30_001067"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000737444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="low molecular weight phosphotyrosine protein
                     phosphatase"
                     /protein_id="HET2447188.1"
                     /translation="MKKLVFVCLGNICRSPMAEFVMKSMTDNYEIQSRATSSWEHGNP
                     IHKGTQGIFQEYEIPYDKNKTSLQISKEDFEAFDYIIGMDASNISDLRQMCPVDCQDK
                     IYSFSSESVPDPWYTGDFEETYRRVQEGCQAWLERLEKES"
     gene            16672..17082
                     /locus_tag="VQU30_001068"
     CDS             16672..17082
                     /locus_tag="VQU30_001068"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000427064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2447189.1"
                     /translation="MENLTNFYEKYRVYLTRPRLELLAVVTIVFCAVLVFFLNIPGKG
                     VLKLDNGTIVYDGSLVRGKMNGQGTITFQNGDQYTGGFNNGAFNGKGTFQSKEGWTYE
                     GDFVNGQAEGKGKLTTEQEVVYEGTFKQGVFQQK"
     gene            17382..20033
                     /gene="adhE"
                     /locus_tag="VQU30_001069"
                     /gene_synonym="adhC"
     CDS             17382..20033
                     /gene="adhE"
                     /locus_tag="VQU30_001069"
                     /gene_synonym="adhC"
                     /EC_number="1.1.1.1"
                     /EC_number="1.2.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000763984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional acetaldehyde-CoA/alcohol
                     dehydrogenase"
                     /protein_id="HET2447190.1"
                     /translation="MADKKTVTPEEKKLVAEKHVDELVQKALVALEEMRKLDQEQVDY
                     IVAKASVAALDAHGELALHAFEETGRGVFEDKATKNLFACEHVVNNMRHTKTVGVIEE
                     DDVTGLTLIAEPVGVVCGITPTTNPTSTAIFKSLISLKTRNPIVFAFHPSAQESSAHA
                     ARIVRDAAIAAGAPENCVQWITEPSMEATSALMNHEGIATILATGGNAMVKAAYSCGK
                     PALGVGAGNVPAYVEKSANIRQAAHDIVMSKSFDNGMVCASEQAVIIDKEIYDEFVAE
                     FKSYHTYFVNKKEKALLEEFCFGVKANSKNCAGAKLNADIVGKPATWIAEQAGFTVPE
                     GTNILAAECKEVGENEPLTREKLSPVIAVLKSESREDGITKARQMVEFNGLGHSAAIH
                     TADEELTKEFGKAVKAIRVICNSPSTFGGIGDVYNAFLPSLTLGCGSYGRNSVGDNVS
                     AINLLNIKKVGRRRNNMQWMKLPSKTYFERDSIQYLQKCRDVERVMIVTDHAMVELGF
                     LDRIIEQLDLRRNKVVYQIFADVEPDPDITTVNRGTEIMRAFKPDTIIALGGGSPMDA
                     AKVMWLFYEQPEVDFRDLVQKFMDIRKRAFKFPLLGKKTKFIAIPTTSGTGSEVTPFA
                     VISDKANNRKYPIADYSLTPTVAIVDPALVLTVPGFVAADTGMDVLTHATEAYVSQMA
                     SDYTDGLALQAIKLVFENLESSVKNADFHSREKMHNASTIAGMAFANAFLGISHSMAH
                     KIGAQFHTIHGRTNAILLPYVIRYNGTRPAKTATWPKYNYYRADEKYQDIARMLGLPA
                     STPEEGVESYAKAVYELGERIGIQMNFRDQGIDEKEWKEHSRELAFLAYEDQCSPANP
                     RLPMVDHMQEIIEDAYYGYKERPGRRK"
     gene            complement(21018..21326)
                     /locus_tag="VQU30_001070"
     CDS             complement(21018..21326)
                     /locus_tag="VQU30_001070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000134125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HET2447191.1"
                     /translation="MTEEMEYICFQLIANSGAAKSSFIEAIQLAKAGNLKEAKIKVEE
                     AEDSLVEAHKIHSNLIQKEATGEKIGFSLLFMHAEDQMASTEIIQLLSKEFIDLYQNK
                     "
     gene            complement(21323..21631)
                     /locus_tag="VQU30_001071"
     CDS             complement(21323..21631)
                     /locus_tag="VQU30_001071"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398044.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HET2447192.1"
                     /translation="MKQILLVCNAGMSTSMLVKKMQQSATERGIEISIQAKSMTEAKK
                     NIHEADVILIGPQIRYELLAVKEIAGNIPVDTIDMRDYGMMNGAKVLEQALAWIGEIR
                     "
     gene            complement(21636..22931)
                     /locus_tag="VQU30_001072"
     CDS             complement(21636..22931)
                     /locus_tag="VQU30_001072"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000798148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HET2447193.1"
                     /translation="MKNSKFIDQFATFAGKLGNQIHLKTLRDAFVTVMPLYILAGLIV
                     LLNNTVFKWIFQGDTLTKFQYWGITIANGTLSISGMIIAVMVGYFLAKNRDFENPSAA
                     SMLSLVSLIVMMPNTVSVVPDGAKDAVNISGVLSFNNTGTGAMFAGVIVAIIATELFI
                     ELSNVKALQMNLGENIPPAVSRSFSVLLPVMTVISLFGIVSALLFNITGMNLISIITI
                     FIQEPIRHIGTSLIGVIIIYSLGNMLWLFGIHQAVIYSAILEPLLLINITENITAANN
                     GQAIPHIINLSQIQTFALMGGSGSTLCLLIATFLVSRNAVSKNVAKLSFGPGIFNINE
                     PVLFGYPIVYNISLAIPFITVPVLGILISYLATVTGFMSPAFIQVPWTTPVFLNAWLA
                     TAGDVRAVLVQFIIFALGVLLYIPFIKVNDKVVEQEMEG"
     gene            complement(22949..24358)
                     /locus_tag="VQU30_001073"
     CDS             complement(22949..24358)
                     /locus_tag="VQU30_001073"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000728302.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HET2447194.1"
                     /translation="MKKKLVFPNLFWWGAASSGPQTEGQYGKVHENVMDYWFKTHPED
                     FFDNVGPLVASNFFHTYTEDFHLMKEIGVNSFRTSIQWSRLIKNLETGEPDPKGIAFY
                     NAIIEEAKKNQMDLVMNLHHFDLPVELLQKYGGWESKHVVELFVKFAKTAFTCFGDKV
                     HYWTTFNEPMVIPEAGYLYAFHYPNLKGKGKEAVQVIYNLNLASAKVIQLYRSLGLDG
                     KIGIILNLTPAYPRSNSPEDLEASRFTEDFFNKVFLNPAVKGTFPERLVKQLERDGVL
                     WSHTEKELQLMKSNTVDFLGVNYYHPKRVQAQANPEEYQTPWMPDQYFKEYEWPERRM
                     NPYRGWEIFPKAIYDIAMIVKEEYGNIPWFISENGMGVENEARFIDENGVIDDVYRIE
                     FYEEHLRWLHKAIEEGSLCFGYHAWTAFDCWSWNNAYKNRYGFISVDLETQKRTIKSS
                     GRWYRKVSDNNGFEVEIEE"
     gene            24516..25244
                     /locus_tag="VQU30_001074"
     CDS             24516..25244
                     /locus_tag="VQU30_001074"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000105270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HET2447195.1"
                     /translation="MSTKYLFIYNEIREKILCNKYTMNEQLPDEMTLAKQFACSRMTI
                     KKALDLLVSEGLIFRKRGQGTFVLSRGSSKRKLIVPERDIRGLTKISEDAHSTIDSRI
                     IHFKLEFANEFLAEKLQVALQSPVYNIYRLRIIDGKPYVLEQTYMSTDVIPGITEDIL
                     QKSIYNYIEGKLGLHIASATKILRASSSSENEQHYLQLLPTEPVFEVEQVAYLDNGTP
                     FEYSISRHRYDLFEFNSFALRHSS"
     gene            25704..25898
                     /locus_tag="VQU30_001075"
     CDS             25704..25898
                     /locus_tag="VQU30_001075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001818644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HET2447196.1"
                     /translation="MKGKEYENRTVSFAISSKGEKMKVENISYRVDHRILFDNISFDT
                     SSSDVTLITGKNGTGKSTLL"
     gene            complement(26264..27574)
                     /locus_tag="VQU30_001076"
     CDS             complement(26264..27574)
                     /locus_tag="VQU30_001076"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000581523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SLC13 family permease"
                     /protein_id="HET2447197.1"
                     /translation="MIHLIMISAIALAIGIGYRTKINIGLLAIAFSYLIATTLMGLSP
                     KELLHFWPTSLFFTIFSVSLFYNFAITNGTLDVLAQHILYRTRTYPNALYMILYLMAT
                     LLSALGAGFFTTMAVCCPLAITLCQKADKHPLIGAQAVNWGASGGANLITSSSGIVFQ
                     GLFKQMGWEEQAFSLGNHIFIVSIIYPLIVLLLLSCYSHYSKGRTNSSLTIDQPPLLS
                     KVQRQTTLLMISSMVLVWLFPLLHLIFPNIAWIATYRKTFDIGFVSILMVCLALRLKL
                     GKQEAILAKVPWATIIMLCGMSLLMSLAVKSGLVTLIGHLMTTSIPHFWLPLFFCVIA
                     GVMSLFSSTLSVVAPALFPIIAIISAQNPQIDIHLLTTATVIGALSTNISPFSSAGSL
                     IQLSLPNIEERGLAFKKQIILGVPISLSLGLLTTWILILLASLS"
     gene            27811..28683
                     /locus_tag="VQU30_001077"
     CDS             27811..28683
                     /locus_tag="VQU30_001077"
                     /EC_number="2.4.2.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000022746.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carboxylating nicotinate-nucleotide
                     diphosphorylase"
                     /protein_id="HET2447198.1"
                     /translation="MSIISTDLTPFQIDDTLKAALREDVHSEDYSTNAIFDHHGQAKV
                     SLFAKEAGVLAGLTVFQRVFTLFDAEVTFQNPHQFKDGDRLTSGDLVLEIIGSVRSLL
                     TCERVALNFLQHLSGIASMTAAYVEALGDDCIKVFDTRKTTPNLRLFEKYAVRVGGGY
                     NHRFNLSDAILLKDNHIAAVGSVQKAIAQARAYAPFVKMVEVEVESLAAAEEAAAAGA
                     DIIMLDNMSLEQIEQAITLIAGRSRIECSGNIDMTTISRFRGLAIDYVSSGSLTHSAK
                     SLDFSMKGLTYLDV"
BASE COUNT         8999 a         5132 c         5987 g         8646 t
ORIGIN      
        1 tcattcgcta attctttttt tagggcgatt gatttgtact tccgtcgcat caatcattac
       61 cgtgtcctca gaactgagag gagttcttga aatcgtaaca ccactttgaa caagagttac
      121 ttcaacccat tggctccgac ggattaagtt gctttcgtgg ataccaaaat cagccgcaat
      181 ttcttcataa gtgcggtatt ctcgcacata ttgaagagtg cccataagaa ggtcttctag
      241 gcttaattta ggttttcgtc caccttttgc gtgtttaagt tgataagctg tttttaatac
      301 agctaacatc tctttaaaag tcgtgcgctg aacaccaaca agacgcttaa attgtgcatt
      361 ggttagttgt ttactttctt cataaatttt attgtatcat atttttgttt cacaggaagt
      421 ctaataaata aaaattcttt aaaattttgt tgggaaaatg ggaaaagata taaatggaaa
      481 cttagtataa cacttggaaa actctgtaaa aatagtaagt caattcatgt cccgtttttt
      541 ctctagggaa gttgggcggc tatatttata tgaccatttg tcgtaataaa catccctacc
      601 aagggtcaat agaaataaat tcaacgaaac ttttgctgtc agatttagat gcccaatttg
      661 tcatttatac tctttcatat aggactttct ataaggatgg aaaaaagaag ggaaatttga
      721 taagatagga atatggattt tgaaaaaatt gaacaagctt atacctattt actagagaat
      781 gtccaagtca tccaaagtga tttggcgacc aacttttatg acgccttggt ggagcaaaac
      841 agcatctatc tggatggtga aactgagcta aaccaggtca aagacaacaa tcaggccctt
      901 aagcgtttag cactacgcaa agaagaatgg ctcaagacct accagtttct cttgatgaag
      961 gctgggcaaa cagaaccctt gcaggccaat caccagttta caccggatgc tattgctttg
     1021 cttttggtgt ttattgtgga agagttgttt aaagaggagg aaattactat cctcgaaatg
     1081 ggttctggga tgggaattct aggcgctact ttcttgatct cgcttgataa aaaggtggat
     1141 tacttgggaa tggaagtgga tgatttgctg attgatctgg cagctagcat ggcagatgta
     1201 attggtttgc aggctggctt tgtccaagga gatgccgttc gtccacaaat gctcaaagaa
     1261 agcgatgtgg tcatcagtga cttgcctgtt ggctattatc ctgatgatgc cgttgcgtcg
     1321 cgccatcaag ttgcttctag ccaagaacat acttacgccc atcacttgct catggaacaa
     1381 gggcttaagt acctcaagtc agacggatac gctatttttc tagctccgag tgatttgttg
     1441 accagtcctc aaagtgattt gttaaaagaa tggctgaaag aagaggcgag tctggttgct
     1501 atgattagtc tgcctgaaaa tctctttgct aatgctaaac aatctaagac tatttttatc
     1561 ctacagaaga aaagtgaaat agcagtggag ccttttgttt atccacttgc tagcttgcaa
     1621 gatgcaagtg ttttaatgaa atttaaagaa aattttcaaa aatggactca aggtactgaa
     1681 atataaaata gattttgtta taatagttga aaacgcttaa aaaggggtat catgttatga
     1741 caaaaacaat tgcaatcaat gcaggaagtt caagtttgaa atggcaatta tacttaatgc
     1801 cagaggaaaa agtgttagcc aaaggtttga ttgaacgtat cggtttgaaa gattcaattt
     1861 caactgtaaa atttgacggc cgttctgaac aacaaatttt ggatatcgaa aatcatacac
     1921 aagctgttaa aattttattg gatgacttga ttcgtttcga tattatcaag gcttatgacg
     1981 agattacagg tgttggccac cgtgttgtag caggtggaga atatttcaaa gaatcaacag
     2041 ttgttgaggg agatgtttta gaaaaagttg aagagttgag tttgttggct cctctacaca
     2101 acccggccaa tgcagcaggt gttcgtgctt tcaaggaatt gttgccagac attaccagtg
     2161 tagttgtttt tgatacttcc ttccacacaa gtatgccaga gaaagcttat cgctaccctc
     2221 taccaacaaa atattacaca gaaaacaagg ttcgtaaata cggtgctcat ggtacaagtc
     2281 accagtttgt agcaggagaa gctgcaaaac tcttgggacg tccattagaa gacttgaagt
     2341 taattacctg tcatattggt aacggaggct caattacagc tgtgaaagcc ggcaaatctg
     2401 tagacacttc tatggggttc actcctcttg gtggtattat gatgggaacg cgtacagggg
     2461 atattgatcc agctatcatt ccttatttaa tgcaatatac agaggatttt aacacaccag
     2521 aagatatcag tcgtgttctt aaccgtgaat caggtctttt gggagtttct gctaattcta
     2581 gcgatatgcg cgatatagaa gcagctgtag cagaagggaa tcacgaggct agcttggctt
     2641 atgaaatgta tgttgaccgt atccaaaaac atatcggtca gtaccttgca gtgctaaatg
     2701 gaacagatgc cattgttttc acagcaggtg tcggtgaaaa tgcagagaat ttccgtcgtg
     2761 atgtaatctc agggatttcg tggtttggtt gtgatgttga tgatgaaaag aatgtctttg
     2821 gcgttacagg agacatctca acagaggcag ctaaaatccg tgtcttggtt attccaacag
     2881 atgaagaatt agtcattgcc cgtgacgttg aacgcttgaa aaaataagtg aaactaaaaa
     2941 aatattcaat acaaggagtt gggaaagtta tttttccagc ttctttttct gatgaaattg
     3001 tccaaaacct tgctatgatt ggcttttttg aaaaatatgg tataatagta gtaatttaat
     3061 agatggagtt gagttttgaa gaaaaacttt cgtgtaaaaa gagagaaaga ttttaaggcg
     3121 attttcaagg aggggacaag ttttgctaat cgcaaatttg tggtctacca attagaaaac
     3181 cagaaaaacc attttcgagt aggtctatca gttagcaaaa aactggggaa tgccgtcact
     3241 agaaatcaaa ttaagcgacg gattcggcat attatccaga atgcaaaagg gagtctggta
     3301 gaagatgtcg actttgttgt cattgctcga aaaggagtcg aaaccttggg atacgcagag
     3361 atggagaaaa atctactcca tgtattaaaa ttatcaaaga tttaccggga aggaaatggg
     3421 agtgaaaaag aaactaaagt tgactagttt gctaggactg tctctgttaa tcatgacagc
     3481 ctgtgcgact aatggggtaa ctagcgatat tacagccgaa tcggctgatt tttggagtaa
     3541 attggtttac ttctttgcga aaatcattcg ctttttatcg tttgatatta gtatcggagt
     3601 ggggattatt ctctttacgg tcttgattcg tacagtcctc ttgccagtct ttcaggtgca
     3661 aatggtggct tctaggaaaa tgcaggaagc tcagccacgc attaaggcgc ttcgagaaca
     3721 atatccaggt cgagatatgg aaagcagaac caaactagag caggaaatgc gtaaagtatt
     3781 taaagaaatg ggtgtcagac agtcagattc tctttggccg attttgattc agatgccggt
     3841 tattttggcc ttgttccaag ccctatcaag agttgacttt ttaaagacag gtcatttctt
     3901 atggattaac cttggtagtg tggatacaac ccttgttctt ccgattttag cagcagtatt
     3961 caccttttta agtacttggt tgtccaacaa agctttgtct gagcgaaatg gcgctacgac
     4021 tgcgatgatg tatgggattc cagtcttgat ttttatcttt gcagtttatg cgccaggtgg
     4081 agtcgcccta tactggacag tgtctaatgc ttatcaagtc ttgcaaacct atttcttgaa
     4141 taatccattc aagattatcg cagagcgcga ggccgtagta caggcacaaa aagatttgga
     4201 aaatagaaaa agaaaagcca agaaaaaggc tcagaaaacg aaataaataa ggaggaatct
     4261 ggtaatggta gtatttacag gttcaactgt tgaagaagca atccagaaag gattgaaaga
     4321 attagatatt ccaagaatga aggctcatat caaagtcatt tctagggaga aaaaaggctt
     4381 tcttggtcta tttggtaaaa aaccagccca agtggatatt gaagcgatta gtgaaacgac
     4441 tgttgtcaaa gcaaatcaac aggtagtaaa aggcgttccg aaaaaaatca atgatttgaa
     4501 cgagcctgtg aagacggtta gtgaagaaac cgttgacctt ggtcatgtgg ttgatgctat
     4561 taaaaaaata gaggaagaag gtcaaggtat ttctgatgaa gtcaaggctg aaatcttaaa
     4621 acatgaaaga catgccagca ctatcttaga agaaactggt cacattgaga ttttaaatga
     4681 acttcaaatc gaggaagcga tgagggaaga agcaggcgct gatgaccttg aaactgagca
     4741 agatcaaact gaaaatcaag acttgaaaga gatgggcttg aaggtcgagc aaagttatga
     4801 tattgcccag gtggctacgg atgtgactgc ctatgttcaa gcgattgtgg atgacatgga
     4861 tgttgaagct acactttcaa atgattataa ccgtcgtagc atcaatctac aaattgacac
     4921 caacgaacca ggtcgtatta tcggctacca tggtaaagtc ttgaaggcct tgcaactgtt
     4981 ggctcaaaat tatctttaca accgctattc caaaaccttc tacgttacaa tcaatgtcaa
     5041 tgattatgtc gaacaccgtg cagaagtctt gcagacctat gcgcaaaaat tggcgattcg
     5101 tgttttagaa gaaggacgta gtcatcaaac agatccaatg tcgaatagtg aacgcaagat
     5161 tatccaccgt attatttcac gtatggatgg cgtgaccagt tactctgaag gtgatgagcc
     5221 aaatcgctat gtcgttgtag atacagaata agtaaaatca gggttgacct gattttttgc
     5281 tagctagagg aggttaaact aatgttgaat aagataagag actatttaga ctttgctggt
     5341 ttgcagtacc gtaatcctga taaagcggga gcagagcgag agaagatgct ggcattccgc
     5401 cacaaaggac aagaggcccg aaaggctttt acagaactgg ccaaagcctt tcaagcaagc
     5461 catccaggat ggcaactcca acagactagt cagtggatga atcaggccca gcgtttgaga
     5521 ccacattttt gggtttatct acagagagac gaacaagtga cagaacctat gatggcctta
     5581 cgtttgtatg ggacatctac tgactttgga atttctttgg aagtcagttt catcgaacgt
     5641 aagaaggatg agcaaacact gggcaagcag gccaaagttt tagacattcc aaccgttaaa
     5701 gggatttatt atctaaccta ctctaatggt caaagtcaac ggtgggaggc gaatgaagaa
     5761 aagcgtcgta ctttacgcga gaaggtgaga agtcaagaag ttcgaaaagt tttagtgaag
     5821 gtagatgttc ctatgacaga aaattcgtct gaagaagaaa tcgtagaagg cttattgaag
     5881 tcttattcta aaattcttcc ctattatcta gctacgagaa aataagataa tttgtaaaac
     5941 atcataaatc atacagtcca agagtgaaca gtccgctgtg taattcttgg tctttttgtt
     6001 tgcgctttcg cattatataa taaacttaca aaaacaattc aaaaggagaa caattatgga
     6061 agtcgtttca agtgttctaa attggttttc tagcaatatt ttgcagaatc ccgcattttt
     6121 cgtaggttta ttggtgttga taggatatgc acttttgaaa aaacctgccc atgacgtttt
     6181 ttcagggttt gttaaagcaa cagtagggta tatgttgctt aacgtgggtg ctggtggttt
     6241 ggttacaacc tttcgtccaa tcttagcagc tcttaactac aaattccaaa ttggtgcagc
     6301 ggttatcgac ccttactttg gacttgctgc agcaaacaac aaaattgcag cagagtttcc
     6361 agattttgtt ggaactgcaa ctacagctct attgattggt tttggaataa atatcttgct
     6421 cgtagctctt cgaaagatta cgaaggtaag aaccctcttt attactggtc acatcatggt
     6481 acaacaagct gcaacagtat ctcttatggt tctattctta gtaccacaat tgcgcaatgc
     6541 ttacggtaca gcagcgattg gtatcatctg tggactttac tgggcagtta gttcaaatat
     6601 gactgttgag gcaactcaac gcttgactgg tggtggcgga tttgcgattg gtcaccaaca
     6661 gcaatttgca atctggtttg tagataaagt agcaggacgc tttggtaaga aagaagaaag
     6721 tttagacaat cttaaattac ctaagttcct ctcaatcttc cacgatacag ttgttgcatc
     6781 tgctaccttg atgctcgtat tcttcggagc cattctttta atcttgggtc cagacattat
     6841 gtctaataaa gaagtcatca cttcaggaac tctattcaat cctgctaaac aagatttctt
     6901 tatgtacatt atccaaacag cctttacctt ctcagtttac ttgttcgttt tgatgcaagg
     6961 tgtccgaatg ttcgtatctg agttgacaaa cgccttccaa ggtatttcaa acaaattgtt
     7021 gccaggttca ttcccagcgg ttgacgttgc agcttcttat ggatttggtt ctccaaatgc
     7081 tgtcttgtca ggatttacct ttggtttgat tggtcaattg attacaattg ttttgctcat
     7141 cgtctttaaa aatccgattc ttattattac aggatttgta ccagtgttct ttgacaatgc
     7201 agccattgcg gtctacgctg ataaacgcgg cggatggaaa gcggctgtta tcctttcctt
     7261 tatatcaggt gtccttcaag ttgctctagg agctctttgt gtggcccttc tcgatttggc
     7321 atcttatggt ggctaccatg gaaatatcga ctttgaattc ccatggcttg gatttggata
     7381 tatcttcaaa taccttggta ttgttggtta tgtacttgtg tgtctcttct tgcttgttat
     7441 tcctcaactt caatttgcca aagcaaaaga taaagagaaa tattacaacg gtgaagttca
     7501 agaagaagct tagtatctag aaaaggagaa ataaaatggt taaagtatta gcagcgtgcg
     7561 gaaatggaat gggttcatca atggttatca agatgaaggt tgaaaatgct ctccgtaagc
     7621 ttaatcaaac agattttaca gtcaattcat gcagtgtcgg tgaagctaaa ggtttagcag
     7681 taggatatga cattgtaatc gcttctcttc atttgattca agaattggaa gggcgaacta
     7741 atgggaagtt aattgggctt gataacttga tggatgataa agaaatcacc gaaaaactca
     7801 gtcaagcact acagtaaaag gttggagggg gctggacaga aactgagagt tatcgtttct
     7861 gtccagcccc ctctttaaat aaaggaggca gatatgaatt taaaacaagc tttaattgac
     7921 aatgactcga tccgactagg tttagaggct aacaattgga aagaagcagt caaggtagca
     7981 gtagatccct tgattgaaag tggggcaatt ttgccagagt attacgatgc tatcattgaa
     8041 tcgactgaag agtatgggcc ttactatatc ttgatgccag gtatggctat gccccacgct
     8101 agacctgaag ctggtgtgca aagtgatgcc ttttcattga ttaccttaca aaatcctgtt
     8161 gtattttcag atgggaaaga ggtatctgtt ttgttggcac tagcagcaac aagttcaaaa
     8221 attcacacaa gtgtagccat tccacaaatt attgccctgt ttgaattaga agattctatt
     8281 gcacgtttac aggcttgcca gactaaagaa gatgtcttgg ctatgattga agaatctaag
     8341 gatagccctt atctcgaagg attggatttg gaaagttaga aagaggaata aagaaatgac
     8401 aaaaagaata cctaatttac aagttgcatt agaccattca gacttgcaag gagcgattaa
     8461 agcagctgtt tctgttggtc aggaagtaga tattatcgaa gctggaactg tttgcttgct
     8521 tcaagttgga agtgaactgg ctgaagtctt gcgtagcctt ttcccagata agattattgt
     8581 ggcagacaca aaatgtgctg atgctggtgg aacagttgct aaaaataatg cggttcgtgg
     8641 agcagactgg atgacttgta tctgttgtgc aaccatccct actatggaag cagctctaaa
     8701 ggctatcaag actgaacgag gagaacgagg cgaaatccag atcgagcttt atggcgattg
     8761 gacttttgaa caagctcagc tttggctaga tgcaggtatc tcacaagcta tttatcacca
     8821 atctcgtgat gctcttcttg ctggtgaaac ttggggtgaa aaagacctta ataaggttaa
     8881 aaaactcatt gacatgggct tccgtgtatc tgtaacaggt ggtctagatg tagatactct
     8941 caaactcttt gaaggtgttg atgtctttac ctttatcgca ggtcgtggaa ttacagaggc
     9001 tgcggatcca gcaggagcag cgcgtgcctt caaggatgaa atcaaacgaa tttgggggta
     9061 aatcatggta cgtccaattg gaatttatga aaaggcaacc ccaacacact ttacttggct
     9121 agaacgttta aattttgcca aggagttagg ctttgatttt gtcgagatgt ctattgacga
     9181 acgtgacgag cgtttagcaa gacttgactg gagtaaggaa gaacgcttgg aagttgtcaa
     9241 agaaatctat gaaactggtg ttcgtattcc ttctatctgt ttttcaggcc atcgtcgcta
     9301 cccattgggt tcaaaagatc cagttctaga ggaaaaatct ctagaactca tgaaaaaatg
     9361 tatcgaatta gctcaagact tgggagttcg tacgattcaa ttagctggtt acgatgttta
     9421 ctatgaggaa aagtcacccc agacacgcca acgttttatc aaaaatttga gaaaagcctg
     9481 tgactgggct gaagaagctc aggtggtact tgctattgaa attatggatg atcctttcat
     9541 caatagcatc gaaaaatatt tggctataga aaaagagatt gactctccct tcctctttgt
     9601 atatccagat attggtaatg tgtctgcatg gcataatgat atctatagtg agttttatct
     9661 tggtcatcat gccatcgcag ctctccatct caaggatact tatgcagtga cagaaagttc
     9721 aaggggccag ttccgagatg taccttttgg gcaaggttgt gtcaaatggg aagaagcttt
     9781 cgatatttta aaggaaacca attataatgg acctttccta atcgaaatgt ggtctgaaaa
     9841 ttgtgaaaca gtagaagaaa cacgcgcagc cattcaagag gcgcaagctt ttctctatcc
     9901 actcattaag aaagcaggtt tgatgtaaga tgaatcaagt aatcaatgct atgcgtaaac
     9961 gagtctgtga tgccaatcaa tcattgccaa aacatggact tgtcaaattt acctggggga
    10021 atgtatctga agtcaatcgc gaactcggtg tcattgttat caaaccatca ggcgtggatt
    10081 atgacgaatt gacacctgaa aacatggtag tgactgatct agatggtaag atcctagaag
    10141 gggatttaag accatcttcc gacctcccaa ctcatgtgca attatataag gcttggtcag
    10201 aaattggtag tgtggttcac acccattcga cagaagctgt tgcttgggct caggcaggtc
    10261 gtgatattcc tttctacgga acaacccatg cagattattt ctacggttca atcccttgcg
    10321 cccgtagttt gaccaaggac gaagtagaag tggcctatga aaaagatact ggcctggtta
    10381 tcgtagaaga gtttgaacat cgcggactta acccggttga agtaccagga attgttgtac
    10441 gcaatcacgg tccattcacc tggggcaaaa atccagagaa tgctgtttat cactctgtcg
    10501 tactagagga agtatcaaag atgaatcgct ttacagaaca aatcaatcca agagttggac
    10561 ctgctcccca gtacatacta gaaaaacact accaacgtaa acatggacca aatgcttatt
    10621 atggtcaaaa gtaagaacga tgaaggagga gaaaaagata aatttagctc ctctttttac
    10681 atttgatttt tattgagagt aaagttggag ttgaagtaat tttaaaagat tttttagaaa
    10741 tagcgcttga tatatatatg gtaaaataaa aagaattgct gtgatatcaa tagatttggg
    10801 ggatttttta atatggtact ggataaggca agttgtgatt tgcttcaata tttgatggat
    10861 caagaaacgt ccaaaacgat tatggcgatt tcgaaagatt tgaaagagtc aagaaggaaa
    10921 atttattatc acattgacaa aatcaatgct gctctgggtg acgaggcgct tcacatcatt
    10981 agtattccac gaattggtat tcacttaacg gaagagcaga gagatgcttg ttgtaaacta
    11041 ttatcggaag tagattcgta cgattatatc atgagtgcgc atgaacgtat gatgataatg
    11101 ttactatgga taggtatttc taaagaacgt attacgattg aaaaattgat agagttaaca
    11161 gaggtatcta ggaatactgt tctcaatgat ttgaatagta ttcgttatca actaactttg
    11221 gaacaatatc aggtgatctt gcaagtgagc aagtcacagg gataccacct tcatgcccac
    11281 cctcttaata aaattcagta tcttcaatcg cttctatatc atatttttat ggaagaaaat
    11341 gccacttttg tatctatttt agaagataag atgaaagaga ggttagatga tgagtgtttg
    11401 ctttctgttg aaatgaacca attttttaag gaacaggttc ctttagttga acaagattta
    11461 gggaagaaaa taaaccatca tgaaataact tttatgttgc aggttctacc ttatttgctg
    11521 ttaagctgtc ataatgttga acagtatcaa gaaagacatc aggatataga gaaagaattt
    11581 tctttgataa gaaaaagaat agagtatcag gtgtctaaga aattaggaga acggttgttt
    11641 caaaagtttg aaatttcttt gtcaggactt gaagtttctc ttgtagctgt tctcctcctc
    11701 tcctatcgta aagatttgga tattcatgca gaaagtgatg attttcggca attaaaactt
    11761 gctttagaag aatttatctg gtattttgaa tcacaaatcc gaatggagat tgagaacaag
    11821 gatgatttgt tacgaaattt gatgatccac tgtaaagcct tgttatttag aaagacttac
    11881 ggtatttttt ctaaaaatcc tctaacaaaa caaattcgat ccaagtatgg agaattattt
    11941 ttagtcacta gaaaatctgc ggaaatttta gaaggagcat ggtttattcg gctaacagac
    12001 gatgatattg cctatttgac gattcatatt ggaggatttt taaaatatac accatcatct
    12061 caaaaaaata tgaaaaaagt ttatctcgtt tgtgatgaag gtgttgcggt ttcgagactt
    12121 ttgctgaaac aatgcaaact ttattttcca aatgagcaaa ttgacactgt atttacaaca
    12181 gaacaattta agagtgtgga agatattgca caagttgatg tagtgattac tactaatgat
    12241 gatttggata gcagatttcc gattttaagg gttaatccta tccttgaagc agaagatatt
    12301 ttgaaaatgc tagactatct taaacacaat atatttcgta ataagagcaa aagtttcagt
    12361 gaaaatcttt ctagtcttat ttcgtcttat attgtagaca gcaagttggc tagtaagttc
    12421 caagaagagg ttcaaacact tataaatcaa gaaatagtag ttcaagcttt tttggaagat
    12481 atttgaagga cagtccaatg atgaacacaa acctgtgttt ttcttggtct tttttagtgt
    12541 tttgaagggt ggtatactaa tctcaaagat aacaattata tccaaaggag gcaacatatg
    12601 ccaaacgtca aagaaattac aagagagtca tggattttag ccactttccc agagtgggga
    12661 acatggttga acgaagaaat cgaagaagaa gtcgtacctg aaggcaactt tgccatgtgg
    12721 tggctaggca actgtggtac ttggattaag acaccagctg gtgctaacgt tgtcatggac
    12781 ctttggtcaa accgtggaaa atcaaccaaa aaagtgaaag atatggttcg tgggcaccaa
    12841 atggcaaata tggcaggtgt tcgtaagctg caaccaaact tgcgtgttca gccaatggtt
    12901 atcgatccat ttgctatcaa cgaactagac tattacttag tttcacactt ccacagtgat
    12961 catatcgacc catacacagc tgcagcaatt ctcaataatc ctaagttaga gcatgttaag
    13021 tttatcggtc cttaccactg tggacgaatc tgggaaggat ggggtgttcc aaaagaacgt
    13081 atcatcgttg ttaaaccagg tgacactatc gaattaaaag atatgaagat tcatgcagta
    13141 gaatcatttg accgtacttg cttggtaact ctcccagtga acggtgctga tgagacaggc
    13201 ggtgaacttg ctggcttggc tgttacagat gaagaaatgg ctcaaaaggc tgttaactat
    13261 atctttgaaa caccaggtgg aaccatctat catggtgcag attctcactt ctcaaactat
    13321 tttgcaaaac atggtaaaga ctttaaaatt gatgttgctt tgaataacta tggtgaaaat
    13381 ccggtaggta tccaagacaa aatgacatct atcgaccttc ttcgtatggc agaaaatctg
    13441 cgtaccaaag tcattatccc agttcactat gatatctggt ctaacttcat ggcttctact
    13501 aatgagattc tagaactttg gaaaatgcga aaagatcgct tgcaatacga tttccatcca
    13561 tttatctggg aagttggcgg taagtacact tatcctcaag atcaacactt agtagaatac
    13621 catcatccac gtggttttga tgattgtttt gaacaagact ctaacattca atttaaagct
    13681 ttgctataat ataaaaatat tctttggagg ttatccgtat gttgcatgat acggataatt
    13741 ttcatataat agtaaaatag aatgtgtgat tcaataatca cctcaaatag aaaggaaatt
    13801 ctatgtcaaa tctatctgtt aatgcaattc gttttctagg tattgacgcc attaataaag
    13861 ccaactcagg tcatccaggt gtggttatgg gagcggctcc gatggcttac agcctcttta
    13921 caaaacaact tcatatcaat ccagctcaac caaactggat taaccgcgac cgctttattc
    13981 tttcagcagg tcatggttca atgctccttt atgctcttct tcacctttct ggttttgaag
    14041 atgtcagcat ggatgagatt aagagtttcc gtcaatgggg ttcaaaaaca ccaggtcacc
    14101 cagaatttgg tcatacggca gggattgatg ctacgacagg tcctctaggg caagggattt
    14161 caactgctac tggttttgcc caagcagaac gtttcttggc agccaaatat aaccgtgaag
    14221 gttacaatat ctttgaccac tatacttacg ttatctgtgg agacggagac ttgatggaag
    14281 gtgtctcaag cgaggcagct tcatacgcag gcttgcaaaa acttgataag ttggttgttc
    14341 tttatgattc aaatgatatc aacttggatg gtgagacaaa ggattccttt acagaaagtg
    14401 ttcgtgaccg ttacaatgcc tacggttggc atactgcctt ggttgaaaat ggaacagact
    14461 tggaagccat ccatgctgct atcgaaacag caaaagcttc aggcaagcca tctttgattg
    14521 aagtgaagac ggttattgga tacggttctc caaacaaaca aggaactaat gctgtacacg
    14581 gcgcccctct tggagcagat gaaactgcat caactcgtca agccctcggt tgggactacg
    14641 aaccatttga aattccagaa caagtatatg ctgatttcaa agaacatgtt gcagaccgtg
    14701 gcgcatcagc ttatcaagct tggactaaat tagttacaga ttataaagaa gctcatccag
    14761 aactggctgc agaagtagaa gccatcatcg acggacgtga tccagtcgaa gtgactccag
    14821 cagacttccc agctttagaa aatggttttt ctcaagcaac tcgtaattca agtcaagatg
    14881 ccttgaatgt tgtggcagct aaattaccaa cctttctagg tggatcagct gaccttgctc
    14941 actcaaacat gacttatatc aagacggatg gacttcaaga cgatgccaat cgcttgaatc
    15001 gtaacattca gtttggtgtt cgtgaatttg caatgggaac aatcttgaac gggatggccc
    15061 ttcatggtgg acttcgtgta tacggtggaa ctttcttcgt cttctctgac tatgtgaagg
    15121 cagctgtccg cttgtcagcc ttacaaggac ttcctgtgac ttatgtcttt acccatgatt
    15181 caatcgcagt tggggaagat ggtccgactc atgaaccagt tgagcattta gcaggtcttc
    15241 gtgctatgcc aaatctaaat gttttccgtc cagcagatgc gcgtgaaacg caagcagctt
    15301 ggtaccttgc agtgacaagt gagaaaacac caactgccct tgtcttgaca cgtcaaaatt
    15361 tgactgttga agatggaaca gacttcgaca aggttgctaa aggtgcttat gttgtatatg
    15421 aaaatgcagc cgactttgat accatcttga ttgcgacagg ttcagaggtt aatcttgctg
    15481 tctcagctgc taaagaattg gctagtcaag gcgaaaaaat ccgcgtagtc agcatgccat
    15541 ctacagatgt ctttgataaa caagatgcag cttacaagga agaaattctt ccaaatgcag
    15601 tccgccgtcg tgttgcagtc gaaatgggtg caagtcaaaa ctggtacaaa tatgttggtc
    15661 tcgatggtgc cgttctaggt attgatacct tcggagcctc tgccccagca ccaaaagtat
    15721 tggcagaata tggctttact gtagaaaatc ttgtaaaagt tgttcgaaac ttgaaataat
    15781 cctaaaaatc agggcgtaag ctctggtttt tcttaccaga aaagtaaggt acaatcttgt
    15841 aaaagtagct gaaatttgat atagtagtcc tatgtaaaag acaaaggaga aaacaatgaa
    15901 tccaaatatt acttttttaa tcatgcttgt aggtatgatg gccttgatgt tctttatgca
    15961 acgttctcaa aagaaacaag ctcaaaagcg tatggaaagc ttaaataaac tacaaaaagg
    16021 ctatgaagtg attacaatcg gtggacttta tggaacagtc gatgaagtag atacggagaa
    16081 gggaacaata gttcttgacg tagagggagt ttacttgact tttgaactag ctgctatcaa
    16141 gacagtatta ccgctgaaag aaacagcttc actagaaggc gcaattgaaa aataagacgg
    16201 gatcacgaac tcccgttttt ctataaaaga aaggaaatgg gatgaaaaaa ttagtctttg
    16261 tctgtctggg aaatatttgc cgtagcccta tggccgagtt tgttatgaaa tcaatgacag
    16321 ataactacga aatccaaagt cgagcaactt cctcttggga acatggcaat ccgattcata
    16381 aggggactca gggaattttt caagagtatg agattcctta tgacaagaac aagacatcgc
    16441 ttcagattag taaggaagat tttgaagcct ttgattatat tatcggaatg gacgcttcaa
    16501 atatttctga cttacgtcag atgtgtccag tagactgtca agataagatt tactcatttt
    16561 catctgaaag tgttccagac ccttggtata caggagattt tgaagaaacc tatcgacgtg
    16621 ttcaagaggg ctgtcaagct tggttagaac gtttagaaaa ggagagttaa ggtggaaaat
    16681 cttacgaatt tttacgaaaa gtatcgtgtc tatctgactc gtccacgttt agagcttttg
    16741 gcagtagtta ccattgtttt ctgtgctgta ctcgtctttt ttctaaatat tccaggaaaa
    16801 ggtgtcttaa aactcgataa tggaacgatt gtttatgatg gcagtcttgt ccgcggtaaa
    16861 atgaatggcc aaggtaccat taccttccaa aatggagacc aatatacagg tggcttcaac
    16921 aatggagcct tcaacggaaa aggtaccttt caatctaaag aaggctggac ctacgaaggt
    16981 gattttgtaa atggtcaggc tgaaggaaaa gggaaactaa caacagaaca agaagtcgtt
    17041 tatgaaggaa cttttaaaca aggcgttttt caacaaaaat aaagcctcct tatcaaagga
    17101 ggtattatta gaatcgcaag gtaagcgctt acctgcaaat ccctttcttt ccaaatccct
    17161 cttccaagca agtttgtgaa ataaaaaata tttgaaataa atttcacaaa cttcaaagat
    17221 aaaacctgat aagaaaagaa aatgagaaaa gtttcacaag agtttaaaaa ttctttgtga
    17281 aatgtttatg aaactgttta caaagttgaa ataatgcgtt ataataaact tgtgaaaaaa
    17341 ttaacaaagg atatcgttcc ttgaaagcta tggaggaaaa tatggctgat aaaaaaactg
    17401 tgacaccaga ggaaaagaaa ctcgttgctg aaaaacacgt agatgagttg gttcaaaaag
    17461 ctctagttgc ccttgaagaa atgcgtaaat tggatcaaga acaagttgac tacatcgttg
    17521 ccaaagcatc agtagcagct ttggatgccc acggagaatt ggctttacat gcctttgaag
    17581 aaacaggacg tggtgtattt gaagataaag caactaagaa cttgtttgct tgtgaacacg
    17641 tggtaaacaa catgcgtcac actaaaacag ttggcgttat cgaagaagat gatgtaacag
    17701 gattgaccct gattgctgaa ccagttggtg ttgtttgtgg tatcactcca acaacaaacc
    17761 caacatcaac agcgatcttc aaatcattga tttcattgaa gacacgtaat ccaatcgtct
    17821 ttgccttcca tccatcagct caagaatcat cagctcatgc agctcgtatc gtccgcgatg
    17881 cagctatcgc agctggtgct cctgaaaact gtgtacagtg gatcactgaa ccatctatgg
    17941 aagcaactag tgcccttatg aaccacgaag gtattgcaac aatccttgca acaggtggta
    18001 atgccatggt taaagccgca tactcatgtg gtaaaccagc tcttggggta ggtgccggaa
    18061 acgttccagc ttatgttgaa aaatcagcaa acattcgtca agcagcacac gatatcgtca
    18121 tgtctaaatc atttgataac ggtatggtct gtgcatctga acaagcagtt atcattgata
    18181 aagaaattta cgatgaattt gtagcagagt tcaaatctta ccacacttac tttgtaaaca
    18241 aaaaagaaaa agctcttctt gaagagttct gcttcggcgt caaagcaaac agcaaaaact
    18301 gtgctggtgc aaaattgaac gctgacatcg ttggtaaacc agcaacttgg attgcagaac
    18361 aagcaggatt tacagttcca gaaggaacaa acattcttgc tgcagaatgt aaagaagttg
    18421 gcgaaaatga gccattgact cgtgaaaaat tgtcaccagt tattgcagtt ttgaaatctg
    18481 aaagccgtga agatggtatt actaaggctc gtcaaatggt tgaatttaac ggtcttggac
    18541 actcagcagc tatccacaca gctgacgaag aattgactaa agaatttggt aaagctgtta
    18601 aagctattcg tgttatctgt aactcacctt ctacttttgg tggtatcggg gacgtttaca
    18661 atgccttctt gccatcattg acacttggat gtggttctta cggacgcaac tcagttgggg
    18721 ataacgttag tgccattaac ctcttgaata tcaaaaaagt cggaagacgg agaaataaca
    18781 tgcaatggat gaaacttcct tcaaaaacat actttgaacg tgattcaatt caataccttc
    18841 aaaaatgtcg tgacgttgaa cgtgtcatga tcgttactga ccatgccatg gtagagcttg
    18901 gtttccttga tcgtatcatc gaacaactgg accttcgtcg caataaggtt gtttaccaaa
    18961 tctttgcgga tgtagaaccg gatccagata tcacaactgt aaaccgtggt actgagatta
    19021 tgcgtgcctt caaaccagat accatcatcg cactcggtgg tgggtctcca atggatgctg
    19081 ccaaagtaat gtggctcttc tacgagcaac cagaagtgga cttccgtgac cttgtccaaa
    19141 aattcatgga tatccgtaaa cgtgccttca agttcccatt gcttggtaag aagactaaat
    19201 tcatcgcgat tccaactaca tctggtacag gatctgaagt aacaccattt gccgttatct
    19261 ctgataaagc aaacaaccgt aaatacccaa tcgctgacta ctcattgaca ccaactgtgg
    19321 caatcgtaga tcctgctttg gtattgacag ttccaggatt tgttgctgct gatactggta
    19381 tggacgtatt gactcacgcg acagaagcat acgtatcaca aatggctagt gactacactg
    19441 atggtttagc acttcaagcc attaaattgg tctttgaaaa tctcgaaagc tcagttaaga
    19501 atgcagactt ccactcacgt gagaaaatgc ataacgcttc aacaatcgct ggtatggcct
    19561 ttgccaatgc cttcctaggt atttctcact caatggccca taagattggt gcgcaattcc
    19621 acacaatcca cggtcgtaca aatgctatct tgcttccata cgttatccgt tacaacggta
    19681 cacgtccagc taagacagca acatggccta agtacaacta ctaccgtgca gatgaaaaat
    19741 accaagatat cgcacgcatg cttggacttc cagcttctac tccagaagaa ggggttgaat
    19801 cttacgcaaa agctgtctac gaactcggtg aacgtattgg gatccaaatg aattttagag
    19861 accaaggaat tgacgaaaaa gaatggaaag aacattctcg tgaattagcc ttcctggctt
    19921 atgaagacca atgttcacca gctaacccac gtcttccaat ggtagaccat atgcaagaaa
    19981 tcatcgaaga tgcatactat ggctacaaag aaagaccagg acgccgtaaa taattgttta
    20041 tcagtctaga agcaagacaa aaactcaatt tgagggaaag atccagtaat ttttctatga
    20101 taaaaggcat cctatcaagg tttttgaaca cctgatagga tgccttttta tgatattgag
    20161 gcctttttgc cctttttgaa aaactagaat agaaacaaaa tatataatag attgaaactg
    20221 gaatagtaca cttctgcttc taaaacattg ttagaattcg atttgactgt cctgatcgat
    20281 ttgtcctatt cctatttcat tttactatat aaaaaatata gtatagtaga ctgaatctaa
    20341 aatagtacga aacaattgct aaaacattta tagaaattaa ttttactttc ctgatagagt
    20401 tgttcacatc ttatttcaat tcactatagt ttaatttaag agtagtattt actaaggccc
    20461 aattaaaatc aaagagcaaa ctagaaaacg agtgccattc agctcaaaac actgatttga
    20521 gattgcagat aagactagcc cctcattaac aggtttacga taaaacgatg acaaggtgtg
    20581 ttgctttttg atttctaaag agtataatga tagatctcta taaaataagt gcgaaggaaa
    20641 tgagctttta tagtcctttc gttttaaaat actatctcag atgttcttat atcgacaaga
    20701 agtttttgag tcattccctc atcatacata ttaaataaat agtggctcat tcaatttttt
    20761 actagaataa taagctagta tagtaaactg aaataagata taaacaaata aattggagct
    20821 taacatctat ttccagcaat tttttagaaa ctgcagtgga ctattctaaa ttcaacacat
    20881 tataaaaact agagtaaaag aaaaggattg gatcttgtgt aatgcaggat ctaatccttt
    20941 caatcatttt gtccaacttt tggaggttcc tacaatgtag ccgtcattaa taaagacaga
    21001 tgggaacgac agtgttccta tttattttga tagagatcga tgaattcttt agatagcaac
    21061 tgaataatct ctgttgaagc catttggtct tctgcatgca taaatagcaa ggagaatcct
    21121 attttttctc cagtagcttc tttttgtatg agattagagt gaatcttgtg cgcttctact
    21181 aaggagtctt ccgcttcttc aactttaatt ttcgcttctt ttaaatttcc tgccttagct
    21241 agttggatgg cttcaataaa ggatgatttg gctgctccac tattggcaat gagctgaaaa
    21301 cagatatatt ccatttcttc tgtcatctta tttctcctat ccatgcaagt gcttgttcca
    21361 gaacttttgc tccattcatc attccgtaat cccgcatatc aatggtatct acagggatat
    21421 ttcctgcaat ttctttcaca gcaagtaact cataacgaat ttgtggccca attagaatga
    21481 catctgcttc atggatattc tttttcgctt ctgtcattga ttttgcttgg atagaaattt
    21541 caatcccacg ttcagtcgca ctttgttgca tttttttaac aagcatactt gtcgacattc
    21601 ccgcattaca tactaataaa atttgtttca taatcttaac cttccatttc ttgctcaaca
    21661 actttgtcat taactttgat aaatggaatg tatagaagaa ctccaagtgc aaagatgatg
    21721 aattgaacta gaactgctct cacgtcccct gctgttgcta accatgcatt taagaatact
    21781 ggtgtagtcc aaggaacttg tataaatgca ggactcatga atcctgtaac tgttgctaag
    21841 tagctgatta aaataccaag gactggaact gtgataaatg gaatagctaa tgaaatgtta
    21901 taaacgattg ggtaaccgaa taatactggt tcattgatat tgaagatacc aggtccaaaa
    21961 gataatttag ccacgttttt agaaacagca ttgcgactca ctaagaatgt tgctattaat
    22021 aaacataatg tagatccact accacccatt aaagcgaatg tttgtatttg tgataagttg
    22081 atgatgtgtg gaatggcttg tccattattt gctgcagtga tgttttcagt aatgttaatt
    22141 aatagtaatg gttctaggat ggcactgtaa ataactgctt ggtgaatacc aaatagccat
    22201 aacatatttc ctaaagagta aataataatg accccgatta agcttgtacc aatatgacga
    22261 attggttctt gaataaagat tgtaatgatt gagattaagt tcattccagt tatattgaat
    22321 aataatgctg aaacaatccc aaataaggag atgacagtca tgactggaag taatacgcta
    22381 aatgatctac taacagctgg tggaatattt tcaccaaggt tcatttgtaa agctttaacg
    22441 tttgataatt caatgaataa ttctgttgca ataatcgcta cgataacccc ggcgaacatt
    22501 gcgcctgtac ctgtgttgtt gaatgaaaga acacctgaaa tgtttacagc atcttttgct
    22561 ccgtcaggaa ctacagaaac tgtatttggc atcatcacaa ttaaagaaac taatgatagc
    22621 attgatgctg ctgacgggtt ttcgaaatct ctgtttttag ctaagaaata accaaccatt
    22681 acagcaataa tcatacctga aatacttaaa gtaccgtttg caattgttat tccccaatat
    22741 tggaattttg ttaatgtatc cccttggaaa atccacttaa ataccgtgtt gttcaaaaga
    22801 acgattaaac ctgccaaaat atataatggc attactgtta cgaatgcatc tcttagggtt
    22861 tttaaatgaa tttggttccc tagtttacca gcaaaggtgg caaattgatc tataaatttt
    22921 gagtttttca tctgaatatc tcctctcttt actcctcaat ttctacttca aaaccgttat
    22981 tgtcacttac tttgcgatac catcttcctg agctcttgat ggttctcttt tgcgtttcta
    23041 aatcaacgga gataaatccg taacgattct tatatgcatt attccaagac cagcaatcaa
    23101 atgcggtcca agcgtggtat ccaaaacaga gacttccctc ttcaatggct ttatgtagcc
    23161 atcttaaatg ttcttcataa aattcaatac gatacacgtc atcgataact ccattttcat
    23221 cgataaaccg tgcttcgttt tcaacaccca ttccgttctc actgataaac catgggatat
    23281 taccatattc ttccttcaca atcatagcaa tatcataaat ggctttcgga aaaatttccc
    23341 aaccacgata tggattcatg cgacgctccg gccattcata ctctttgaag tattggtctg
    23401 gcatccaggg cgtctgatat tcctcaggat ttgcttgtgc ttgaacacgt tttggatggt
    23461 agtagtttac tccaagaaaa tcaaccgtat ttgatttcat cagttgaagc tctttttcgg
    23521 tatgactcca taacacgcca tctctctcta gctgttttac caatctttct gggaaagttc
    23581 ctttaacagc tggattcaag aagactttgt taaagaagtc ttctgtaaat cgacttgctt
    23641 ctaagtcttc tggagaatta cttcttggat aagcaggtgt caagtttaaa ataatcccaa
    23701 tctttccatc aagtcctaat gagcgatata gttgaatcac ttttgcacta gcaaggttta
    23761 gattatagat gacttgtacg gcctcttttc cctttccttt tagatttgga taatggaaag
    23821 catataagta tcctgcttct ggaatgacca ttggctcatt gaaagttgtc cagtaatgaa
    23881 ccttatctcc aaagcatgtg aaagcagtct tggcaaactt cacgaataac tccactacat
    23941 gtttgctttc ccaaccaccg tatttttgaa gaagttccac tggtaaatca aaatgatgta
    24001 aattcatcac aagatccatc tggttctttt tagcttcttc aatgatggca ttgtagaaag
    24061 caataccttt tggatcaggc tcacctgtct ctaaattctt gatgagtcga ctccattgga
    24121 tggaagtgcg gaaagaatta actccaattt ccttcatcaa gtggaaatct tcggtgtaag
    24181 tatgaaaaaa gttactggct acaagaggtc cgacattatc gaaaaaatct tctggatgcg
    24241 ttttgaacca gtagtccatc acattttcat gtacttttcc atattgacct tctgtctgag
    24301 gtccgctaga agcagctccc caccaaaaca gattaggaaa tactaacttt tttttcatgc
    24361 tcaacctcct ttctattatg ctatacataa agtatagcat aattttaaaa tttgtctaga
    24421 catttttaaa aattgttgat acatatattg tgtttgcctc atttcttgaa ctttgttata
    24481 ctactattag aatattatag agagaaccag attaaatgag tacaaaatat ttatttattt
    24541 acaatgagat tcgtgaaaag attctctgta ataaatatac catgaacgaa caattgcctg
    24601 atgaaatgac attagctaaa cagtttgcct gtagtcgaat gacgatcaaa aaagctttag
    24661 acttgttagt ttctgagggc ttaattttta gaaaacgtgg gcagggaacc tttgttctct
    24721 ctcgtggcag ctcaaaaaga aaattaatcg ttccagaaag agatatccgg ggactgacaa
    24781 aaatatctga agatgctcat tctacaattg actcgaggat tattcacttc aaattagaat
    24841 ttgcaaatga atttttagca gaaaaactac aggtcgcttt gcagagtcca gtttataata
    24901 tttaccgcct gcgtattatt gacggtaaac cttatgttct ggaacaaact tatatgagta
    24961 ccgatgttat tccaggtatt actgaagata ttttacaaaa atcgatttac aattacattg
    25021 aaggaaagtt aggattgcat attgccagtg ctacaaaaat cttgcgagct tcttctagtt
    25081 cagaaaatga gcaacattac ttgcagctcc ttccaacaga accggtattt gaagtagaac
    25141 aagtggctta tttggataac ggaactccgt ttgagtactc gattagtcgt catcgctatg
    25201 atttatttga atttaattct tttgcattac gacattcctc ctaggagaaa atgtgaaaat
    25261 gaagccaatc ttttacaggc tctagtttaa gaaaaattta aaacagggca agaaggtccc
    25321 atctatgctt aaatggtttc tcttttctaa ataagatggc tttaaaagag tgatcgtttt
    25381 atccatcatg ttgaaaaata tcttcgtata gcttatagag taggtactga aattgttcac
    25441 ctgatctact tcttatagtt atttagtttt aaatagtgtt tcaaacattc ttacactgac
    25501 gagaagtttt tgagtctttt cttgtaacac atatagtata ctgaggttag aatagtagac
    25561 tgtgacttct aacaaattgc tagaaatgaa tttcaatctc ccaatttatt tgcttatata
    25621 ttattttaat atattaaata aattctggat cataatcatt taaaaaaatt ttattttttt
    25681 atttttcatt acgaataata tagatgaagg ggaaagagta tgaaaacaga actgtttctt
    25741 ttgctattag ttcaaaagga gaaaaaatga aagtagaaaa tatttcgtat agggtggatc
    25801 atcgtatatt gtttgataat atttcttttg atacttcgag ttcagacgtg acattaatta
    25861 ctggtaaaaa tggtacagga aagtcaactt tactatagtg gattgaaact agaatagtac
    25921 acatctactt ctaaaatatt gttagaaatc gatttgacta tcctgatcta tttgtcctgt
    25981 tcttatttca tttcactata tctcaaattg agtatgacga agtgcgctcc catgtcctgg
    26041 gaacgcactt tcttcatatt tttcatattc ttgaatccat cgataaagac tattgggatg
    26101 aatttttaaa gttgaactaa tcatttttac aggatgaggt ttacagcaga gagtttgaag
    26161 gctttatcaa aggtttttct tggcataatg acttttcctc gtttccactt aattttgtgt
    26221 ctactttatt ataccaagtc cacccttaag ttagataata aatctaactt aaggaagcta
    26281 gaaggatgag aatccaggtg gtcaagagtc ccaaacttaa gctgattggg acacccagaa
    26341 taatttgctt tttgaaggca aggccacgtt cctctatatt gggaagtgag agttgaatga
    26401 gagaaccagc tgatgaaaag ggtgagatat tagtagatag agcgccaata acggtggctg
    26461 ttgtgagtaa gtgaatatca atctggggat tttgagcact gatgatagca atgatgggaa
    26521 agagggctgg agctacaacg gatagggtgg aactaaagag tgacatcacc ccggctatca
    26581 cacaaaagaa cagaggtaac cagaaatgag gaatggatgt tgtcatgagg tgccctatca
    26641 gtgtgactaa acctgacttg accgctagag acattagtaa gctcatgccg cagagcatga
    26701 taattgtagc ccagggaact ttagccaaaa tggcttcttg cttccctaat ttgagcctta
    26761 aggcgaggca gaccatgagt attgagacaa agccaatatc aaatgttttt cgataagtag
    26821 ctatccaggc gatgtttggg aaaatgagat gcaacaaggg aaaaagccaa accaaaacca
    26881 tgctgctgat catgagcaag gtggtttgtc tttgaacctt gctgaggagt ggtggttggt
    26941 caatagtcaa ggatgagttt gttcttccct tactatagtg actgtaacag gataataaaa
    27001 gcaagacaat gagtgggtag ataatgctga cgataaagat atgattgcca agtgaaaaag
    27061 cttgctcttc ccatcccatt tgcttaaaca ggccttgaaa gacaatgcct gagctactgg
    27121 ttatcaaatt agcccctcct gaagctcccc aattgacggc ttgagctcca atcaaagggt
    27181 gtttgtccgc tttttgacag agagtaatcg ctagaggaca gcaaacggcc atagtagtga
    27241 aaaatccagc acctaaagca gacaaaaggg ttgccatcag gtataaaatc atgtagaggg
    27301 cgttagggta ggtgcgtgtg cggtagagaa tgtgttgagc caaaacatca agagtaccgt
    27361 tagttattgc aaagttataa aagagagaga cgctaaaaat ggtaaaaaag agtgaggttg
    27421 gccaaaaatg aagaagttct ttggggctta atcccatgag agtggttgcg atgaggtaag
    27481 aaaaagcaat agccagcagg ccaatattga ttttggtgcg gtaaccaatt ccaatggcta
    27541 gagcaatggc gctaatcatt attaaatgaa tcattgaatt gtcctttcag ttagaatatg
    27601 gaaataggtt ggcaattttg gcgctcaaaa gaccacctgt ttcctattgg tacttgacta
    27661 ttatacacaa aaaaaataca attgtcttga caattgtatt gacacttgtt agaattaaaa
    27721 atgaggtatt caggcttgtg atttcctatg gaagttaata gtgattgcct ctaatgctta
    27781 caagtgatat taaaaataga ggacctagtg atgtcaatca tttcaactga tttaacccct
    27841 tttcaaatag atgatacatt gaaagcagcc ttgcgagaag atgttcattc cgaagattac
    27901 agtaccaatg ccatttttga tcatcatggc caagccaagg tgtcgctttt tgccaaggaa
    27961 gctggtgttt tagcggggct aaccgttttt caaagggttt ttaccctatt tgatgccgag
    28021 gtgaccttcc agaatcctca tcaatttaag gatggggatc gtttgactag tggcgatttg
    28081 gttttagaaa tcataggctc ggtgagaagt ctcttaacat gtgaacgcgt tgccttgaat
    28141 tttttacaac atttatcagg gattgcttcg atgacagctg cttatgtaga agccttaggc
    28201 gatgattgca ttaaggtatt tgatactcga aaaactactc ctaatttacg tctttttgag
    28261 aaatatgcag tgagagttgg cggtggctat aatcatcgct ttaatttatc agatgctatc
    28321 ctgctaaaag acaatcacat tgcggcagta ggtagtgttc aaaaggcaat tgctcaagcg
    28381 cgtgcctatg ccccttttgt gaaaatggtc gaggtggaag tggaaagcct tgctgctgcc
    28441 gaagaagctg cggcggcggg tgctgatatt atcatgttgg ataatatgtc attggaacag
    28501 attgaacagg ccattaccct aattgcagga cgttctcgga ttgaatgttc tggaaatatt
    28561 gatatgacca ctattagccg ttttcgtggt ttagcgattg attacgtctc cagtggtagt
    28621 ttaacccata gtgctaagag tcttgatttt tccatgaagg ggttaaccta ccttgatgtc
    28681 taagttgtaa aataaactaa ctttttaaag gatgtctttc ctctagaacg agttttatgt
    28741 cagatagttt aaacgcctct tcaa
//
LOCUS       DAVBBO010000025        28643 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ST1
            SAMEA2066453-rid20184263.denovo.025, whole genome shotgun sequence.
ACCESSION   DAVBBO010000025 DAVBBO010000000
VERSION     DAVBBO010000025.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2066453
            Sequence Read Archive: ERR351777
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 28643)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 28643)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980402.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980402.1
            Genome Coverage       :: 176x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:17:33
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,141
            CDSs (total)                      :: 2,104
            Genes (coding)                    :: 1,953
            CDSs (with protein)               :: 1,953
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 16S)
            partial rRNAs                     :: 1 (23S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 151
            CDSs (without protein)            :: 151
            Pseudo Genes (ambiguous residues) :: 0 of 151
            Pseudo Genes (frameshifted)       :: 73 of 151
            Pseudo Genes (incomplete)         :: 76 of 151
            Pseudo Genes (internal stop)      :: 40 of 151
            Pseudo Genes (multiple problems)  :: 32 of 151
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..28643
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2066453-rid20184263.denovo.025"
                     /strain="ST1"
                     /db_xref="taxon:1313"
     gene            complement(43..1389)
                     /gene="gor"
                     /locus_tag="VQU30_001078"
     CDS             complement(43..1389)
                     /gene="gor"
                     /locus_tag="VQU30_001078"
                     /EC_number="1.8.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015511376.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione-disulfide reductase"
                     /protein_id="HET2447199.1"
                     /translation="MREYDIIAIGGGSGGIATMNRAGEHGAKAAVIEEKKLGGTCVNV
                     GCVPKKIMWYGAQIAETFHQFGEDYGFKTTDLNFDFATLRRNREAYIDRARSSYDGSF
                     KRNGVDLIEGHAEFVDSHTVSVNGELIRAKHIVIATGAHPSIPNIPGAELGGSSDDVF
                     AWEELPESIAILGAGYIAVELAGVLHTFGVKTDLFVRRDRPLRGFDSYIVEGLVKEME
                     RTNLPLHTHKVPVKLEKTTDGITIHFEDGTSHTASQVIWATGRRPNVKGLQLEKAGVT
                     LNERGFIQVDEYQNTVVEGIYALGDVTGEKELTPVAIKAGRTLSERLFNGKTTAKMDY
                     STIPTVVFSHPAIGTVGLTEEQAIKEYGQDQIKVYKSSFASMYSACTRNRQESRFKLI
                     TAGSEEKVVGLHGIGYGVDEMIQGFAVAIKMGATKADFDATVAIHPTASEEFVTMR"
     gene            1675..2874
                     /locus_tag="VQU30_001079"
     CDS             1675..2874
                     /locus_tag="VQU30_001079"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000728654.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="efflux RND transporter periplasmic adaptor
                     subunit"
                     /protein_id="HET2447200.1"
                     /translation="MKKKNGKAKKWQLYAAIGAASVVVLGAGGILLFRQPSQTAVKDE
                     PTHLVVAKEGSVASSVLLSGTVTAKNEQYVYFDASKGDLDEILVSVGDKVSEGQALVK
                     YSSSEAQAAYDSASRAVAKADRHINELNQARNEAASAQAPQLPAPVGGEDATVQSPTP
                     VAGNSVASIDAQLGDARDARADAAAQLSKAQSQLDATTVLSTLEGTVVEVNSNVSKSP
                     TGASQVMVHIVSNENLQVKGELSEYNLANLSVGQEVSFTSKVYPDKKWTGKLSYISDY
                     PKNNGEAASPAAGNNTGSKYPYTIDVTGEVGDLKQGFSVNIEVKSKTKAILIPVSSLV
                     MDDSKNYVWIVDEQQKAKKVEVSLGNADAENQEITSGLTNGAKVISNPTSSLEEGKEV
                     KADEATN"
     gene            2858..3559
                     /locus_tag="VQU30_001080"
     CDS             2858..3559
                     /locus_tag="VQU30_001080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016465646.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET2447201.1"
                     /translation="MKQLISLKNIFRSYRNGDQELQVLKNINLEVNEGEFVAIMGPSG
                     SGKSTLMNTIGMLDTPTSGEYYLEGQEVAGLGEKQLAKVRNQQIGFVFQQFFLLSKLN
                     ALQNVELPLIYAGVSSSKRRKLAEEYLDKVELTERSHHLPSELSGGQKQRVAIARALV
                     NNPSIILADEPTGALDTKTGNQIMQLLVDLNKEGKTIIMVTHEPEIAAYAKRQIVIRD
                     GVISSDSAQLGKEEN"
     gene            3561..4820
                     /locus_tag="VQU30_001081"
     CDS             3561..4820
                     /locus_tag="VQU30_001081"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001180420.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HET2447202.1"
                     /translation="MQNLKFAFSSIMAHKMRSLLTMIGIIIGVSSVVVIMALGDSLSR
                     QVNKDMTKSQKNISVFFSPKKSKDGSFTQKQSAFTVSGKEEEVPVEPPKPQESWVQEA
                     AKLKGVDSYYVTNSTNAILTYQDKKVENANLTGGNRTYMDAVKNEIIAGRSLREQDFK
                     EFASVILLDEELSISLFESPQEAINKVVEVNGFSYRVIGVYTSPEAKKSKIYGFGGLP
                     ITTNISLAANFNIDEIASIVFRVNDTSLTPTLGPELARKMTELAGLQQGEYQVADESV
                     VFAEIQQSFSFMTTIISSIAGISLFVGGTGVMNIMLVSVTERTREIGLRKALGATRAN
                     ILIQFLIESMILTLLGGLIGLTIASGLTALAGLLLQGLIEGIEVGVSIPVALFSLAVS
                     ASVGMIFGVLPANKASKLDPIEALRYE"
     gene            4944..6941
                     /gene="metG"
                     /locus_tag="VQU30_001082"
     CDS             4944..6941
                     /gene="metG"
                     /locus_tag="VQU30_001082"
                     /EC_number="6.1.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006155678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionine--tRNA ligase"
                     /protein_id="HET2447203.1"
                     /translation="MSEKNFYITTPIYYPSGKLHIGSAYTTIACDVLARYKRLMGYDV
                     FYLTGLDEHGQKIQQKAEEAGITPQAYVDGMAVGVKELWQLLDISYDKFIRTTDDYHE
                     KVVAQVFERLLAQDDIYLGEYSGWYSVSDEEFFTESQLAEVFRDEAGNVTGGIAPSGH
                     EVEWVSEESYFLRLSKYQDRLVEFFKAHPEFITPDGRLNEMLRNFIEPGLEDLAVSRT
                     TFTWGVPVPSNPKHVVYVWIDALLNYATALGYAQDEHGNFDKFWNGTVFHMVGKDILR
                     FHSIYWPILLMMLDVKLPDRLIAHGWFVMKDGKMSKSKGNVVYPEMLVERYGLDPLRY
                     YLMRNLPVGSDGTFTPEDYVGRINYELANDLGNLLNRTVSMINKYFDGQIPAYVEGVT
                     EFDHVLAEVAEQSIADFHTHMEAVDYPRALEAVWTLISRTNKYIDETAPWVLAKDEAL
                     RDQLASVMSHLAASIRVVAHLIEPFMMETSRAVLTQLGLEEVSSLENLSLADFPADVT
                     VVAKGTPIFPRLNMEEEIAYIKEQMEGNKPAVEKEWNPDEVELKLNKDEIKFEDFDKV
                     EIRVAEVKEVSKVEGSDKLLQFRLDAGDGEDRQILSGIAKYYPNEQELVGKKVQIVAN
                     LKPRKMMKKYVSQGMILSAEYDGKLTLLTVDPAVPNGSVIG"
     gene            6985..7065
                     /locus_tag="VQU30_001083"
                     /pseudo
     CDS             6985..7065
                     /locus_tag="VQU30_001083"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820552.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopyranose mutase"
     gene            7362..7682
                     /locus_tag="VQU30_001084"
     CDS             7362..7682
                     /locus_tag="VQU30_001084"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000665424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="HET2447204.1"
                     /translation="MKETQLLKGVLEGCVLDMIGQKERYGYELVQTLREAGFDTIVPG
                     TIYPLLQKLEKNQWIRGDMRPSPDGPDRKYFSLTKEGEERVSVFWQQWDDLSQKVEGI
                     KNGG"
     gene            7686..8501
                     /locus_tag="VQU30_001085"
     CDS             7686..8501
                     /locus_tag="VQU30_001085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864101.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2447205.1"
                     /translation="MKKMKYYEETSALLHEFSEENQKYFEELWESFNLAGFLYDEDYL
                     REQIYLMMLDFSEAERDGMSAEDYLGKNPKKIMKEILKGAPRSSIKESLLTPILVLAV
                     LRYYQLLSDFSKGPLLTVNLLTFLGQLLIFLIGFGLVATILRRSLVQDSPKMKIGTYI
                     VVGTIVLLVVLGYVGMASFIQEGAFYIPAPWDSLSVFTISLVIGIWNWKEAVFRPFVS
                     MIIAHLVVGSLLRYYEWMGISNVFLTKVIPLAVLFIGIFVLFRGFKKIKWSEV"
     gene            8576..9502
                     /locus_tag="VQU30_001086"
     CDS             8576..9502
                     /locus_tag="VQU30_001086"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001269463.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldo/keto reductase family oxidoreductase"
                     /protein_id="HET2447206.1"
                     /translation="MRYITLGQDDKELSEIVLGMMRIKDKSVKEVEELVETALSVGIN
                     AFDLADIYGRGRCEELLGLVLKNRPDLREKMWIQSKCGIRIEEFTYFDFSKDYIIKSV
                     DGILQRLKIDHLDSLLLHRPDALMESDQVAEAFNLLYKQGKVRDFGVSNQNPMMMELL
                     KKDVKQPLAVNQLQLSAAFTPGFESAFHVNMEDSQAAMRDGSIFEYCQLHDVVIQAWS
                     VLQFGYFKGNFVGNEKFQALNQVLDRLAIKYGVTSSTIAISWILRYPAKMQAVVGTTN
                     PKHLREVSRAANFSLTRKEWYEIYLAAGNNLP"
     gene            9568..9834
                     /locus_tag="VQU30_001087"
     CDS             9568..9834
                     /locus_tag="VQU30_001087"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001808490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2829 domain-containing protein"
                     /protein_id="HET2447207.1"
                     /translation="MKNVELKEKNMTFEEILPGLKAKRKYVRTGWGGAENYVQLFDTI
                     EQNGLALEMTPYFLINVSGEGEGFSMWSPTVCDVLATDWVEVHD"
     gene            9827..10525
                     /locus_tag="VQU30_001088"
     CDS             9827..10525
                     /locus_tag="VQU30_001088"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006151199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-oxoacyl-ACP reductase"
                     /protein_id="HET2447208.1"
                     /translation="MTKRVLITGVSSGIGLAQARLFLEKGYQVYGVDQGEKPLLEGDF
                     HFLQRDLTLDLEPIFDWCPQVDVLCNTAGVLDDYKPLLEQTAQDIQEIFEINYIIPVE
                     LTRYYLTQMLENKKGIIINMCSIASSLAGGGGHAYTSSKHALAGFTKQLALDYAEAGI
                     QVFGIAPGAVKTAMTAADFEPGGLADWVASETPIKRWIEPEEIAELSLFLASGKASAM
                     QGQILTIDGGWSLK"
     gene            10536..11015
                     /locus_tag="VQU30_001089"
     CDS             10536..11015
                     /locus_tag="VQU30_001089"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000403355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HET2447209.1"
                     /translation="MEIKKHFGVYAVCLENGKLLCIEKTRGPYQHRYDLPGGSQQLGE
                     GLTETLTREVMEETGFTVRSYSNPRIYDVFVREELTNFMVDHVMALYDVEMNESAPQV
                     TTSEAVSDGANDSLGYIWMDIQEITEENASPLVLKVKSELLGFPELDKTSYMNWKVK"
     gene            11023..11751
                     /locus_tag="VQU30_001090"
     CDS             11023..11751
                     /locus_tag="VQU30_001090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000418695.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HET2447210.1"
                     /translation="MELFKTWKKNMVLYGLKSQIGTVYRNNDRTTSFYDVGNFLYLAG
                     ELDSRFWEDFVRKYGLDYKIIISENTNWQDFLHRKVGLNSFTRYSFKDKANFQVEFLN
                     NLVTHLEEGYNIVPIDNHIYNCFSTEEWSQDLQGDFESYQDFVLKGGFGFVILKNNEL
                     IAGISSGLVYRKAVEVEVATRPNEQGNGFAKKLGAAMILESLNRDMFPLWDAHNEASK
                     KVAEFLGYELSEPYEAFELEEILI"
     gene            11793..12662
                     /locus_tag="VQU30_001091"
     CDS             11793..12662
                     /locus_tag="VQU30_001091"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866471.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PEP-utilizing enzyme, TIM barrel domain protein"
                     /protein_id="HET2447211.1"
                     /translation="MRNQLALSGEKILEKIYPQLFHHVGMIRGEYLLRELNQNIILAS
                     CQQFVKDYLETICSLYSDEEVWYRFTELTNTEANCLVGTKEFFDEGHPLFGYRGTRRL
                     LACLDEFQAEAHVVTEVYQTNPNLSVIFPFVNDADQLKQAITVLRQYGFTGKVGTMIE
                     LPSAYFDLSSILETGISKIVVGMNDLTSFVFATMRNSQWHDLESPIMLDMLRDMQDKA
                     RKNKINFAVAGYLNTSFIQKMNQLGIKCIIHYSSIPEIFDLEIDHPDHLKHIKEESKK
                     LQRSTHDTARNVE"
     gene            12637..13077
                     /locus_tag="VQU30_001092"
     CDS             12637..13077
                     /locus_tag="VQU30_001092"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012512572.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ASCH domain-containing protein"
                     /protein_id="HET2447212.1"
                     /translation="MIPQEMWNKYKQINPLIGDEIDAWAFGVEPDLLADLVFKGEKTA
                     TASAYDLYVLEDEPLPQVGTFDVILDSQNQSVCIVEITKVSVELFNQVSAQHAFKEGE
                     GDKSLAYWRQVHEDFFTDCLGEVGLTFTPESKVVLEEFRKVYPL"
     gene            13201..15747
                     /locus_tag="VQU30_001093"
     CDS             13201..15747
                     /locus_tag="VQU30_001093"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001149089.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M1 family metallopeptidase"
                     /protein_id="HET2447213.1"
                     /translation="MQAVEHFIKQFVPEHYDLFLDLSRETKTFSGKVTITGQAQSDRI
                     SLHQKDLEITSVEVAGQARPFTVDHDNEALHIELAEAGQVELVLAFSGKITDNMTGIY
                     PSYYTVDGVKKEVLSTQFESHFAREAFPCVDEPEAKATFDLSLRFDQAEGELALSNMP
                     EIDVENRKETGIWKFETTPRMSSYLLAFVAGDLQGVTAKTKNGTLVGVYSTKAHPLSN
                     LDFSLDIAVRSIEFYEDYYGVKYPIPQSLHIALPDFSAGAMENWGLVTYREVYLVVDE
                     NSTFASRQQVALVVAHELAHQWFGNLVTMKWWDDLWLNESFANMMEYVCVDTIEPSWN
                     IFEDFQTGGVPLALERDATDGVQSVHVEVKHPDEINTLFDGAIVYAKGSRLMHMLRRW
                     LGDADFAKGLHAYFEKHQYSNTIGSDLWDALGQASGRDVAAFMDSWLEQPGYPVLTVK
                     VENDVLKISQKQFFIGENEDKNRLWVVPLNSNWKGLPDTLETESIEIPGYAALLAENE
                     GALRLNTENTAHYITDYQGDLLEAVLAELETLDNTSKLQIVQERRLLAEAGHIAYADL
                     LPVLDKLAKEESYLVVSAVSQVISALERFIDEGTDAETAFKGLVAKLARHNYDRLGFE
                     AKDGESDEDELVRQLAVSMMIRSNDAEASQVASQIFATHKENLAGLPAAIRSQVLINE
                     MKHHETKDLLALYLDTYTHATDAVFKRQLAAALAYSTDADNIQNLITSWKDKFVVKPQ
                     DLSAWYYQFLAHQATQKTAWSWARENWAWIKAALGGDMSFDSFVILPAHVFKTQQRLA
                     EYKEFFEPQLSDLALSRNIGMGIKEIAARVDLISREKAAVEAVVLQYGNA"
     gene            15856..16530
                     /gene="ciaR"
                     /locus_tag="VQU30_001094"
     CDS             15856..16530
                     /gene="ciaR"
                     /locus_tag="VQU30_001094"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004256510.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system response regulator CiaR"
                     /protein_id="HET2447214.1"
                     /translation="MIKILLVEDDLGLSNSVFDFLDDFADVMQVFDGEEGLYEAESGV
                     YDLILLDLMLPEKNGFQVLKELREKGITTPVLIMTAKESLDDKGHGFELGADDYLTKP
                     FYLEELKMRIQALLKRSGKFNENTLTYGNIVVNLSTNTVKVEDTPVELLGKEFDLLVY
                     FLQNQNVILPKTQIFDRLWGFDSDTTISVVEVYVSKVRKKLKGTTFAENLQTLRSVGY
                     LLKDVQ"
     gene            16520..17854
                     /gene="ciaH"
                     /locus_tag="VQU30_001095"
     CDS             16520..17854
                     /gene="ciaH"
                     /locus_tag="VQU30_001095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000491790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system sensor histidine kinase
                     CiaH"
                     /protein_id="HET2447215.1"
                     /translation="MFSKLKKTWYADDFSYFIRNFGVFTLIFSTMTLIILQVMHSSLY
                     TSVDDKLHGLSENPQAVIQLAINRATEEIKDLENARADASKVEIKPNVSSNTEVILFD
                     KDFTQLLSGNRFLGLDKIKLEKKELGHIYQIQVFNSYGQEEIYRVILMETNISSVSTN
                     IKYAAVLINTSQLEQASQKHEQLIVVVMASFWILSLLASLYLARVSVRPLLESMQKQQ
                     SFVENASHELRTPLAVLQNRLETLFRKPEATIMDVSESIASSLEEVRNMRFLTTSLLN
                     LARRDDGIKPELAEVPTSFFNTTFTNYEMIASENNRVFRFENRIHRTIVTDQLLLKQL
                     MTILFDNAVKYTEEDGEIDFLISATDRNLYLLVSDNGIGISTEDKKKIFDRFYRVDKA
                     RTRQKGGFGLGLSLAKQIVDALKGTVTVKDNKPKGTIFEVKIAIQTPSKKKK"
     gene            complement(17888..18175)
                     /locus_tag="VQU30_001096"
     CDS             complement(17888..18175)
                     /locus_tag="VQU30_001096"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001145225.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3270 domain-containing protein"
                     /protein_id="HET2447216.1"
                     /translation="MPVRKLQSYEVDYQEELNQQLPHYQAYTPEAQSDANLKEILFFI
                     NIAVFCICIAIFSFIFLALKLSTALAFAAAIGFSLLVLKVQRSIIKRKRRR"
     gene            18315..19244
                     /locus_tag="VQU30_001097"
     CDS             18315..19244
                     /locus_tag="VQU30_001097"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006154193.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="U32 family peptidase"
                     /protein_id="HET2447217.1"
                     /translation="MEKIVITATAESIEQVEQLLEAGVDRIYVGEKDFGLRLPTTFSY
                     DQLREIAKLVHDAGKELLVAVNALMHQDMMDRIKPFLDFLEEIKTDYITIGDAGVFYV
                     VNRDGYSFKTIYDASTMVTSSRQINFWGQKAGASEAVLAREIPSAELFKMPEILEIPA
                     EVLVYGASVIHHSKRPLLQNYYNFTHIDDEKTHKRDLFLAEPSDPESHYSIFEDNHGT
                     HIFANNDLDLMIKLTELVEHGFTRWKLEGLYTPGQNFVEIAKLFIQARSLIQEGNFSH
                     DQAFLLDEEVRKLHPKNRFLDTGFYDYDPDMVK"
     gene            19443..21893
                     /locus_tag="VQU30_001098"
     CDS             19443..21893
                     /locus_tag="VQU30_001098"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional DnaQ family
                     exonuclease/ATP-dependent helicase"
                     /protein_id="HET2447218.1"
                     /translation="MKTIGNRYVVVDLEATSTGSKAKIIQVGIVVIEDGEIVDHYTTD
                     VNPHEPLDAHIKELTGLTDQRLAQAPDFSQVARKIFDLVEDGIFVAHNVQFDANLLAE
                     NLFFEGYELRNPRVDTVELAQVFFPELEKYSLPILCRELGIPLKHAHTALSDAQATAE
                     LLLFLREKMTQLPKGLLERLLEMADALLYESYLVIEETYRNQSILSSPDLVQVQGLYF
                     KKTAASLEPRKLSQDFSKNISLLNLEVREEQESFAKEVGLLLKDEPVSLIQAPTGIGK
                     TYGYLLPALSQSKERQIVLSVPTKILQNQIMEEEGKRLKEVFHTDIHSLKGPQNYLKL
                     DAFYHSLQENDENRLFRRFKMQVLVWLTETETGDLDEIGQLYRYQHFLADLRHDGNLS
                     SQSLFVTEDFWKRSQERAETCKLLVTNHAYLVTRLEDNPEFVSDRLLIIDEVQKILLA
                     LENLLQETYDIQSIIDLIDKALVGEENRVQQRILESIRFECLYLIEQFQSGKSRKNIL
                     DSLDNLHQYFSELEVEGFDELVRYFTAEGDYWLEVTETSQKKIHISSTKSGRTLLSSL
                     LPESCQAMGVSATLEISQRVSLADLLGYPEAKFVKIESRGKQEQEVVMVKDFPLVTET
                     SLEVYAREVAALLVEIQAFQQPILVLFTAKDMLLAVSDLLTVSHLAQYKNGDVHQLKK
                     RFEKGEQQILLGAASFWEGVDFSSHPFVIQVVPRLPFQNPQEPLTKKINQELNQEGKN
                     AFYDYQLPMAIIRLKQALGRSMRREYQRSLTLILDRRIIGKRYGKQIVASLAEEATVK
                     TISRSEVDEAIDRFFNEL"
     gene            21930..23153
                     /locus_tag="VQU30_001099"
     CDS             21930..23153
                     /locus_tag="VQU30_001099"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000830656.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsW/RodA/SpoVE family cell cycle protein"
                     /protein_id="HET2447219.1"
                     /translation="MKRSLDSRVDYSLLLPVFFLLVIGVVAIYIAVSHDYPNNILPIL
                     GQQVAWIALGLVIGFVVMLFNTEFLWKVTPFLYILGLGLMILPIVFYNPSLVASTGAK
                     NWVSINGITLFQPSEFMKISYILMLARVIVQFTKKHKEWRRTVSLDFLLIFWMILFTI
                     PVLVLLALQSDLGTALVFVAIFSGIVLLSGVSWKIIIPVFVTAVTGVAGFLAIFISKD
                     GRAFLHQIGMPTYQINRILAWLNPFEFAQTTTYQQAQGQIAIGSGGLFGQGFNASNLL
                     IPVRESDMIFTVIAEDFGFIGSVLVIALYLMLIYRMLKITLKSNNQFYTYISTGLIMM
                     LLFHIFENIGAVTGLLPLTGIPLPFISQGGSAIISNLIGVGLLLSMSYQTNLAEEKSG
                     KVPFKRKKVVLKQIK"
     gene            23164..23718
                     /locus_tag="VQU30_001100"
     CDS             23164..23718
                     /locus_tag="VQU30_001100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269792.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DJ-1/PfpI family protein"
                     /protein_id="HET2447220.1"
                     /translation="MVKVAVMLAQGFEEIEALTVVDVLRRANITCDMVGFEEQVTGSH
                     AIQVRADHVFDGDLSDYDMIVLPGGMPGSAHLRDNQTLIQELQSFEQEGKKLAAICAA
                     PIALNQAEILKNKRYTCYDGVQEQILDGHYVKETVVVDGQLTTSRGPSTALAFAYELV
                     EQLGGDAESLRTGMLYRDVFGKNQ"
     gene            23803..24366
                     /locus_tag="VQU30_001101"
     CDS             23803..24366
                     /locus_tag="VQU30_001101"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398926.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HET2447221.1"
                     /translation="MKYHDYIWDLGGTLLDNYETSTAAFVETLALYGITQDHDSVYQA
                     LKVSTPFAIETFAPNLENFLEKYKENEARELEHPILFEGVSDLLEDILNQGGRHFLVS
                     HRNDQVLEILEKTSIAAYFTEVVTSSSGFKRKPNPESMLYLREKYQISSGLVIGDRPI
                     DIEAGQAAGLDTHLFTSIVNLRQVLDI"
     gene            24381..26327
                     /gene="gyrB"
                     /locus_tag="VQU30_001102"
     CDS             24381..26327
                     /gene="gyrB"
                     /locus_tag="VQU30_001102"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002283665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase (ATP-hydrolyzing) subunit B"
                     /protein_id="HET2447222.1"
                     /translation="MTEEIKNLQAQDYDASQIQVLEGLEAVRMRPGMYIGSTSKEGLH
                     HLVWEIVDNSIDEALAGFASHIQVFIEPDDSITVVDDGRGIPVDIQEKTGRPAVETVF
                     TVLHAGGKFGGGGYKVSGGLHGVGSSVVNALSTQLDVHVHKNGKIHYQEYRRGHVVAD
                     LEVVGDTDRTGTTVHFIPDPKIFTETTTFDFDKLNKRIQELAFLNRGLQISITDKRQG
                     LEQTKHYHYEGGIASYVEYINENKDVIFDTPIYTDGEMDDITVEVAMQYTTGYHENVM
                     SFANNIHTHEGGTHEQGFRTALTRVINDYARKNKLLKDNEDNLTGEDVREGLTAVISV
                     KHPNPQFEGQTKTKLGNSEVVKITNRLFSEAFSDFLMENPQIAKRIVEKGILAAKARV
                     AAKRAREVTRKKSGLEISNLPGKLADCSSNNPAETELFIVEGDSAGGSAKSGRNREFQ
                     AILPIRGKILNVEKASMDKILANEEIRSLFTAMGTGFGAEFDVSKARYQKLVLMTDAD
                     VDGAHIRTLLLTLIYRYMKPILEAGYVYIAQPPIYGVKVGSEIKEYIQPGADQEIKLQ
                     EALARYSEGRTKPTIQRYKGLGEMDDHQLWETTMDPEHRLMARVSVDDAAEADKIFDM
                     LMGDRVEPRREFIEENAVYSTLDV"
     gene            26409..28136
                     /gene="ezrA"
                     /locus_tag="VQU30_001103"
     CDS             26409..28136
                     /gene="ezrA"
                     /locus_tag="VQU30_001103"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000064817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="septation ring formation regulator EzrA"
                     /protein_id="HET2447223.1"
                     /translation="MSNGQLIYLMVAIAVILVLAYVVAIFLRKRNEGRLEALEERKEE
                     LYNLPVNDEVEAVKNMHLIGQSQVAFREWNQKWVDLSLNSFADIENNLFEAEGYNHSF
                     RFLKASHQIDQIESQITLIEEDIAAIRNALADLEKQESKNSGRVLHALDLFEELQHRV
                     AENSEQYGQALDEIEKQLENIQSEFSQFVTLNSSGDPVEAAVILDNTENHILALSHIV
                     DRVPALVTTLSTELPDQLQDLEAGYRKLIDANYHFVETDIEARFHLLYEAFKKNQENI
                     RQLELDNAEYENGQAQEEINALYDIFTREIAAQKVVENLLATLPTYLQHMKENNTLLG
                     EDIARLNKTYLLPETAASHVRRIQTELESFEAAIVEVTSNQEEPTQAYSVLEENLEDL
                     QTQLKDIEDEQISVSERLTQIEKDDINARQKANVYVNRLHTIKRYMEKRNLPGIPQTF
                     LKLFFTASNNTEDLMVELEQKMINIESVTRVLEIATNDMEALETETYNIVQYATLTEQ
                     LLQYSNRYRSFDERIQEAFNEALDIFEKEFDYHASFDKISQALEVAEPGVTNRFVTSY
                     EKTRETIRF"
BASE COUNT         8659 a         5114 c         6299 g         8571 t
ORIGIN      
        1 aaaaagaagc agacatattt atatcagctt cttttgtttc gattaacgca tggttacaaa
       61 ttcttcagat gcagttgggt gaattgccac agttgcatca aagtcagcct tggttgctcc
      121 cattttgata gcaacggcaa atccctgaat catttcatca acgccgtagc caattccatg
      181 aagtccgaca actttttctt ctgaaccagc tgttatgagt ttgaaacggg attcttgacg
      241 gttgcgagtg caagcagagt acatagatgc aaagcttgat ttataaacct tgatttggtc
      301 ttgaccgtat tctttaatag cttgctcttc tgtcaaacca acagttccga tagcagggtg
      361 tgaaaagaca acagttggaa tagttgagta atccattttt gcagtagttt ttccgttaaa
      421 gagacgttca gatagggtac gtccggcctt gattgcaact ggagtcagtt ctttctcgcc
      481 cgttacatca cctagagcat agattccctc aacaacagta ttttggtatt catccacttg
      541 gataaagcca cgttcgttca gagtcactcc agctttttca agttgcaagc ccttaacgtt
      601 tggacggcga cctgtagccc agataacttg gctagctgtg tgactagtac catcttcgaa
      661 atgaatggta atgccgtcag tagttttttc taacttgaca gggactttgt gagtgtgaag
      721 tggtaagttt gttctttcca tttccttgac caaaccttca acgatgtagg aatcaaaacc
      781 acgtaaagga cgatcgcggc gaacaaagag atctgtcttg acaccaaaag tgtggagtac
      841 gccagctaat tcaacggcga tataaccagc gcctagaatg gcaattgact ctggaagttc
      901 ttcccaggca aatacatcat cagaagagcc acctagctca gcaccaggaa tattaggaat
      961 acttggatgg gcacctgtag caatcacgat atgtttagca cgaatcagtt caccatttac
     1021 gcttacagta tgagaatcta caaattcagc atgaccttca atcaagtcta caccgttgcg
     1081 tttaaaacta ccatcataag aagaacgagc gcgatcaatg taggcttcac gattgcgacg
     1141 tagggttgca aagtcaaagt taagatcagt agtcttaaag ccgtagtctt ctccaaattg
     1201 atggaaagtc tcagcgattt gcgccccgta ccacatgatt tttttaggaa cacaaccgac
     1261 gttgacacag gttccaccta atttcttttc ctcaataacg gctgctttgg ctccatgttc
     1321 accagcacgg ttcatggtag cgattcctcc gctacctcca ccgatagcaa tgatatcata
     1381 ttctctcatt gaaaactcct ttgtaatctt ttaaatagta gagtgtcttt tttgatagtt
     1441 atattttatt ctttttttga tttgattgca aaaatctgct acgcacaaaa aattgcaaaa
     1501 aagcttgcca aataagtcaa gatagtgtat tatatatcta gtacaataga aaagcaaaat
     1561 tccgaacgat tgtttaatcc tgaactgcca ttatttccat ctgaactgca ttgtttgctg
     1621 gagggaaatt tggtataata gcaaagtatt gtaaaaaaga aaaggagttt cattatgaag
     1681 aaaaagaatg gtaaagctaa aaagtggcaa ctgtatgcag caatcggtgc tgcgagtgta
     1741 gttgtattgg gtgccggggg gattttactt tttagacaac cttctcagac tgctgtaaaa
     1801 gatgagccta ctcatcttgt tgttgccaag gaaggaagcg tggcatcctc tgttttattg
     1861 tcagggacag taacagcaaa aaatgaacaa tatgtttatt ttgatgctag taagggtgat
     1921 ttagatgaaa tccttgtttc tgtgggcgat aaggtcagcg aagggcaggc tttagtcaag
     1981 tacagtagtt cagaagcgca ggcggcctat gattcagcta gtcgagcagt agctaaggca
     2041 gatcgtcata tcaatgaact caatcaagca cgaaatgaag ccgcttcagc tcaggctcca
     2101 cagttaccag cgccagtagg aggagaagat gcaacggtgc aaagcccaac tccagtggct
     2161 ggaaattctg ttgcttctat tgatgctcaa ttgggtgatg cccgtgatgc gcgtgcagat
     2221 gctgcagcgc aattaagcaa ggctcaaagt caattggatg caacaactgt tctcagtacc
     2281 ctagagggaa ctgtagtcga agtcaatagc aatgtttcta aatctccaac aggggcgagt
     2341 caagttatgg ttcatattgt cagcaatgaa aatttacaag tcaagggaga attgtctgag
     2401 tacaatctag ccaacctttc tgtaggtcaa gaagtaagct ttacttctaa agtgtatcct
     2461 gataaaaaat ggactgggaa attaagctat atttctgact atcctaaaaa caatggtgaa
     2521 gcagctagtc cagcagccgg gaataataca ggttctaaat acccttatac tattgatgtg
     2581 acaggcgagg ttggtgattt gaaacaaggt ttttctgtca acattgaggt taaaagcaaa
     2641 actaaggcta ttcttattcc tgttagcagt ctagtaatgg atgatagtaa aaattatgtc
     2701 tggattgtgg atgaacaaca aaaggctaaa aaagttgagg tttcattggg aaatgctgac
     2761 gcagaaaatc aagaaatcac ttctggttta acgaacggtg ctaaggtcat cagtaatcca
     2821 acatcttcct tggaagaagg aaaagaggtg aaggctgatg aagcaactaa ttagtctaaa
     2881 aaatatcttc agaagttacc gtaatggtga ccaagaactg caggttctca aaaatatcaa
     2941 tctagaagtg aatgagggtg aatttgtagc catcatggga ccatctgggt ctggtaagtc
     3001 cactctgatg aatacgattg gcatgttgga tacaccaacc agtggagaat attatcttga
     3061 aggtcaagaa gtggctgggc ttggtgaaaa acaactagct aaggtccgta accaacaaat
     3121 cggttttgtc tttcagcagt tctttcttct atcgaagctc aatgctctgc aaaatgtaga
     3181 attgcccttg atttacgcag gagtttcgtc ttcaaaacgt cgcaagttgg ctgaggaata
     3241 tttagacaag gttgaattga cagaacgtag tcaccattta ccttcagaat tatctggtgg
     3301 tcaaaagcaa cgtgtagcca ttgcgcgtgc cttggtaaac aatccttcta ttatcctagc
     3361 ggatgaaccg acaggagcct tggataccaa aacaggtaac caaattatgc aattattggt
     3421 tgatttgaat aaagaaggaa aaaccattat catggtaacg catgagcctg agattgctgc
     3481 ctatgccaaa cgtcagattg tcattcggga tggggtcatt tcgtctgaca gtgctcagtt
     3541 aggaaaggag gaaaactaag atgcagaatc tgaaatttgc cttttcatct atcatggctc
     3601 acaagatgcg ttctttgctt actatgattg ggattattat cggtgtttca tcagttgttg
     3661 tgattatggc tttgggtgat tccctatctc gtcaagtcaa taaagatatg actaaatctc
     3721 agaaaaatat tagcgtcttt ttctctccta aaaaaagtaa agatgggtct tttactcaga
     3781 aacaatcagc ttttacggtt tctggaaagg aagaggaagt tcctgttgaa ccgccaaaac
     3841 cgcaagaatc ctgggttcaa gaggcagcta aactgaaggg agtggatagt tactatgtaa
     3901 ccaattcaac gaatgccatc ttgacctatc aagataaaaa ggttgagaat gctaatttga
     3961 caggtggaaa cagaacttac atggacgctg ttaagaatga aattattgca ggtcgtagtc
     4021 tgagagagca agatttcaaa gagtttgcaa gtgttatttt gctagatgag gaattgtcca
     4081 ttagtttatt tgaatctcct caagaggcta ttaacaaggt tgtagaagtc aatggattta
     4141 gttaccgggt cattggggtt tatactagtc cggaggctaa aaagtcaaaa atatatgggt
     4201 ttggtggctt gcctattact accaatatct cccttgctgc gaattttaat atagatgaaa
     4261 tagctagtat tgtctttcga gtgaatgata ccagtttaac cccaactctg ggtccagaac
     4321 tggcacgaaa aatgacagag cttgcaggct tacaacaggg agaataccag gtggcagatg
     4381 agtccgttgt atttgcagaa attcaacaat cgtttagttt tatgacgacg attattagtt
     4441 ccatcgcagg gatttctctc tttgttggag gaactggtgt catgaacatc atgctggttt
     4501 cggtgacaga gcgcactcgt gagattggtc ttcgtaaagc tttgggtgca acacgtgcca
     4561 atattttaat tcagtttttg attgaatcca tgattttgac cttgttaggt ggcttaattg
     4621 gcttgacaat tgcaagtggt ttaactgcct tagcaggttt gttactgcaa ggtttaatag
     4681 aaggtataga agttggagta tcaatcccag ttgccctatt tagtcttgca gtttcggcta
     4741 gtgttggtat gatttttgga gtcttgccag ccaacaaggc atcgaaactt gatccaattg
     4801 aagcccttcg ttatgaatga gatcaacaag atggacactc gtctatcttg tttttgtatg
     4861 gatttcccta tcgaaattca ttaaaaatgt gatataatga agtgttagaa aaacaggttt
     4921 catttgcctg gaaaggaaaa attatgtctg aaaaaaattt ttatattaca acgccgattt
     4981 actatccatc tgggaaactt catatcggtt ctgcctacac aactatcgca tgtgatgtcc
     5041 tagcacgtta caaacgcctg atgggctacg atgtatttta tctgacaggt cttgatgaac
     5101 atggtcagaa aatccagcag aaagcggaag aagctggtat tacacctcaa gcctatgttg
     5161 atggaatggc ggttggagtt aaagaactct ggcaattact agatatctca tacgataaat
     5221 ttatccgtac aaccgatgac taccatgaaa aagttgtcgc acaggtcttt gaacgcttac
     5281 ttgctcaaga tgatatctac ttgggtgaat actctggttg gtattcagta tcagacgaag
     5341 aattctttac agaaagccag ctggcagaag ttttccgtga tgaagctgga aatgtgactg
     5401 gtggtattgc tccatcaggt catgaggttg aatgggtttc tgaagaatca tacttccttc
     5461 gccttagcaa ataccaagac cgtttggtcg aatttttcaa agctcatcct gaatttatca
     5521 cgccagatgg tcgccttaat gaaatgctac gcaacttcat cgagccaggc ttggaagatt
     5581 tggcggtatc tcgtacaacc tttacatggg gagtgcctgt cccatcaaat ccaaaacacg
     5641 ttgtctacgt ttggattgat gcccttctta actatgcgac agctcttggc tacgctcaag
     5701 acgaacatgg taactttgac aagttctgga atggaacagt cttccatatg gtaggaaaag
     5761 atatccttcg cttccactct atctactggc caatccttct tatgatgttg gatgttaaat
     5821 tacctgatcg tttgattgcc catggttggt ttgtcatgaa agacggaaaa atgtctaagt
     5881 caaaagggaa tgtcgtttac cctgaaatgt tggtagagcg ttatggacta gatccacttc
     5941 gttactacct catgcgtaac cttccagttg gttcagacgg aacctttact cctgaagact
     6001 atgtcggccg tatcaactat gaattggcta atgaccttgg gaacctcctt aaccgtacgg
     6061 tttccatgat taataagtac tttgatggac aaatccctgc ctatgtagaa ggtgtgactg
     6121 aatttgatca tgttcttgct gaggttgcag aacaatcaat cgcagacttc catacacaca
     6181 tggaagcagt tgactatcca cgtgcgcttg aagcagtctg gactctgatc tctcgtacca
     6241 ataaatacat cgatgagacc gcaccatggg tcttggccaa ggatgaagct cttcgtgacc
     6301 aattggcaag tgtcatgagc cacttggcag ccagcattcg tgtagttgct cacttgattg
     6361 aaccatttat gatggaaact agtcgtgcag ttttgactca acttggtttg gaagaagttt
     6421 ctagtcttga aaacttgagt ttggctgact tcccagcaga tgtgactgta gttgccaaag
     6481 gaacacctat ctttccacgt ctaaatatgg aagaagaaat cgcctatatc aaggaacaaa
     6541 tggaaggcaa taaaccagca gtcgaaaaag aatggaatcc ggacgaagtt gagctcaaac
     6601 taaacaagga tgaaatcaag tttgaagact ttgacaaggt tgaaatccgt gtcgcagaag
     6661 tcaaagaagt gtctaaagta gaaggttcag ataagttgct tcaattccgc ttggatgctg
     6721 gtgatggaga agatcgtcag attctttcag gaattgcaaa atactatcca aatgaacaag
     6781 aattggtcgg caagaaagtt caaatcgttg ctaacctcaa accacgtaaa atgatgaaaa
     6841 aatatgtcag ccagggtatg attctatcag ctgaatatga tggcaaatta acccttctca
     6901 cagttgatcc agctgtacca aatggaagtg tgattgggta aaagtagaca ggactagttc
     6961 agactagttc tgttttttta tttatactca atgaaaatca aagagcaaac taggaagcta
     7021 gccgcaggtt gctcaaaaca ctgttttgag gttgtagata gaactgacga agtcagctca
     7081 aaacatgttt ttgaggttgt agatgaaact gacgaagtca gctcaaaaca ctgttttgag
     7141 gttgtagatg aaactgacga agtcagctca aaacactgtt ttgaggttgt agatgaaact
     7201 gacgaagtca gtaaccatac atacggtagg gcgacgctga cgtggtttga agagattttc
     7261 gaagagtatt aactattatg ctttacaaac tagtgtagaa gtaatatact ataggtgaag
     7321 ttactagtag gtattacaaa atagattaga agggagaagt gatgaaagaa actcagctat
     7381 taaaaggtgt tcttgaaggt tgtgtcttgg atatgattgg tcaaaaagag cggtatggtt
     7441 atgagttggt tcagactttg cgagaggctg gatttgatac tatcgttcca ggaactattt
     7501 atcctttgtt gcaaaagtta gaaaaaaatc aatggataag aggcgacatg cgcccgtcgc
     7561 cagatggtcc agatcggaag tatttttcat taacgaaaga aggagaagag cgtgtctcag
     7621 tcttttggca gcaatgggac gatttgagtc aaaaagtaga agggattaag aatgggggtt
     7681 aaaccatgaa gaaaatgaag tattacgaag aaacaagcgc tttgctacat gagttttctg
     7741 aggagaatca aaagtatttt gaggagttgt gggaaagttt taatcttgct ggatttctct
     7801 atgatgaaga ctatctcaga gagcagatct atttgatgat gctagatttc tcagaagcag
     7861 aacgagatgg catgagtgca gaggattatc taggtaagaa tcctaaaaaa ataatgaaag
     7921 agattctcaa gggagcacct cgcagttcta tcaaagagtc ccttttgacg ccaattcttg
     7981 tcctggctgt attacgttat tatcaactac taagtgattt ttctaaaggt cctctcttaa
     8041 cagtcaattt gctcacattt ttagggcaac ttcttatttt tctgattgga tttggacttg
     8101 tggccacaat tttacgaaga agtttagtcc aagattctcc taaaatgaaa attggcactt
     8161 acattgttgt tgggactata gttcttctag ttgttttagg atatgtagga atggcaagct
     8221 tcatacaaga aggagccttt tatattccgg ctccctggga tagtttgtct gtctttacga
     8281 tttcgctagt tatcggtatt tggaattgga aagaagcggt ctttcgtcca tttgtcagta
     8341 tgattattgc ccatcttgtg gtgggttctc tgctccgtta ttatgagtgg atgggaattt
     8401 caaatgtttt ccttacaaaa gttattcctt tagctgtcct ctttattgga atctttgtct
     8461 tgttccgtgg gtttaagaag ataaaatgga gtgaagtata gtcaaaaagc cgttgcaaag
     8521 cggttttttg ttataatgaa gggaagaatg ttagaaatta aaggagaaaa atttgatgag
     8581 atacataact cttggtcaag atgacaaaga attatcagaa attgttctcg gaatgatgag
     8641 aataaaagat aagtctgtaa aagaagttga agagcttgta gaaacagcac tttctgttgg
     8701 aatcaatgcc ttcgacttgg ctgatattta tggtcgtggt cgttgtgaag aactgttagg
     8761 tcttgtccta aaaaatcgtc cagatttaag agaaaagatg tggattcagt ccaaatgtgg
     8821 cattcgcatt gaagaattta cctattttga tttttctaag gactatatta taaaatcagt
     8881 agacggtatt ttgcaaagat tgaagattga tcatctagat agcttgctcc ttcatcgacc
     8941 agatgctttg atggaatctg accaagtagc agaagccttt aatctccttt ataaacaagg
     9001 taaagttcga gattttggag tttctaatca aaatcctatg atgatggagt tgcttaaaaa
     9061 agatgtcaag cagccgttag ctgttaatca gctacaattg agtgcggctt ttactccagg
     9121 atttgaatca gcttttcatg ttaatatgga agatagtcaa gcagctatgc gagatggcag
     9181 catttttgaa tattgccaat tacacgatgt ggtcattcaa gcatggtctg tcttacaatt
     9241 cgggtatttt aaagggaatt ttgttggaaa tgagaaattt caagctttaa atcaagtact
     9301 tgatcgttta gctattaaat atggagtaac ctcttcaact attgccattt cttggatatt
     9361 gcgttatcca gcaaaaatgc aggcagtcgt aggtacaaca aatcctaagc acttgagaga
     9421 agttagccga gcggcaaact ttagcttaac aagaaaagaa tggtatgaaa tttatcttgc
     9481 tgcagggaat aatttgccgt aagtagtagc aggtttgaat aactcacatt caaaaagccg
     9541 tataaagcgg ttttttgcta taattaaatg aagaatgtag aattaaagga gaaaaacatg
     9601 acatttgaag agatcctgcc tgggttaaag gctaagagaa aatatgtacg aactggttgg
     9661 ggaggtgcgg aaaactatgt ccaactcttt gataccatcg agcaaaatgg gcttgcactt
     9721 gaaatgacac cttatttcct aatcaacgtt tctggcgaag gagaaggttt ttccatgtgg
     9781 agcccgacag tttgtgatgt tttggcaacg gattgggtag aagtgcatga ctaaacgtgt
     9841 actcattaca ggagtgagtt cagggatcgg attggctcaa gctcgcctct ttttagagaa
     9901 gggctatcaa gtttatggag ttgaccaagg tgaaaagcca ctcttagagg gtgattttca
     9961 ctttttacag agagatttga ccttggactt ggaacctatt tttgactggt gccctcaggt
    10021 ggatgttttg tgtaatactg ctggagtttt ggatgattac aaaccactgt tggaacaaac
    10081 ggcgcaggac attcaagaga tttttgaaat caactacatt attccagtag agttgactcg
    10141 gtattatttg acacaaatgc tggaaaataa aaagggaatc atcatcaata tgtgttccat
    10201 tgcttctagc ctagcaggtg gaggtggtca cgcctatact tcatccaagc atgccttggc
    10261 tggcttcacc aagcagttgg ctctagacta tgctgaagct gggattcagg tctttggtat
    10321 cgctccagga gcagtcaaga cagctatgac cgctgcggat tttgaaccag gtggtttggc
    10381 tgactgggtg gctagtgaaa ctccaatcaa gcgctggatt gagccagagg aaatagcaga
    10441 gcttagtctt tttttagcaa gtggaaaagc gagcgccatg caaggacaaa tcttgacaat
    10501 agatggtggc tggtctttga agtaggagga gttggatgga aatcaaaaaa cactttggag
    10561 tctacgctgt ttgcttagaa aatgggaagt tactctgcat tgaaaaaacg agaggccctt
    10621 atcaacatcg gtatgatcta cctggaggca gtcagcaact tggtgaagga ctgacggaaa
    10681 cgctgactag agaagttatg gaagagacgg gatttactgt tagaagctac tctaatcctc
    10741 gaatctacga tgttttcgtc agagaagagt taacaaattt tatggttgac catgtcatgg
    10801 ccttgtatga tgttgaaatg aatgagagtg cacctcaagt tacgacttcg gaagctgtgt
    10861 ctgatggtgc gaatgattca cttggatata tttggatgga tattcaagag attacagaag
    10921 aaaatgcatc gccattagtc ttgaaggtta agtctgaatt attaggattt ccagaactgg
    10981 acaagacttc ttacatgaat tggaaggtga agtagaggga taatggaact atttaaaaca
    11041 tggaagaaaa atatggttct ctatggtctt aaatctcaaa ttggaactgt ctaccgaaac
    11101 aatgatagga caacaagctt ttatgatgtt gggaattttc tatacctagc aggggagttg
    11161 gattccagat tttgggaaga ttttgttaga aaatatggtt tagattataa gattattatt
    11221 tcagaaaata ctaattggca agattttctg catcgaaaag tggggctaaa ttcttttact
    11281 cgctattctt ttaaagataa ggcaaatttt caagttgaat ttttaaataa tctagttact
    11341 catttagagg aaggttacaa tattgtgcct attgataatc atatttataa ctgcttttct
    11401 acggaagaat ggtcacagga tttacagggg gattttgagt cctatcagga ttttgtttta
    11461 aaaggtggat ttggctttgt gattcttaaa aataatgaac tgattgctgg gatttcctca
    11521 gggttagttt accgtaaagc agttgaagtg gaagttgcaa ctagaccaaa cgaacaagga
    11581 aatggatttg ctaaaaagct tggtgctgca atgattctag agagtttaaa tagagatatg
    11641 tttccacttt gggatgctca taatgaggct tccaaaaaag tagcagaatt tttaggatat
    11701 gagttatctg aaccttatga agcttttgaa ctagaggaaa ttttgatata attatatatg
    11761 atattgtatc ttttaagacg aggtgaatgg ctatgagaaa tcaacttgcc cttagtggcg
    11821 aaaaaattct tgaaaaaatt tatcctcaac tatttcacca cgtcggcatg attcgtgggg
    11881 aatatttgtt gagagagctt aatcaaaaca tcatattagc aagttgtcag caatttgtaa
    11941 aagattatct agagactatc tgctccctgt actcagatga agaagtttgg tatcgtttta
    12001 ctgaattaac gaatacagaa gccaattgtt tagtggggac taaagagttt tttgacgaag
    12061 ggcatccctt gtttggctat agaggaacca ggcgtttact ggcgtgtttg gatgaatttc
    12121 aggctgaagc acatgtcgtt acagaagttt atcaaaccaa ccccaatcta tctgttatct
    12181 ttccttttgt caatgatgcc gaccaattaa aacaagctat tacagtattg cgtcagtatg
    12241 gctttactgg gaaagtcgga acgatgattg aattaccgtc agcgtatttt gacttatcta
    12301 gtatactgga aacgggcatt tcaaagattg tagttggaat gaatgatttg acttcctttg
    12361 tttttgcgac tatgagaaac agtcaatggc atgatctgga aagtccaata atgttagata
    12421 tgctaagaga tatgcaggat aaagcaagaa agaacaagat taattttgct gtagcaggct
    12481 atctgaatac ttctttcata caaaaaatga atcagttggg tatcaagtgc attatccact
    12541 acagttctat tccagagatt tttgatttag agattgacca tccagatcat cttaaacaca
    12601 taaaagaaga aagtaaaaaa ttacaaagga gtacccatga taccgcaaga aatgtggaat
    12661 aaatacaagc aaatcaatcc tttgatcgga gatgaaatcg atgcttgggc ttttggagtt
    12721 gaaccagacc ttttagcgga tttggtgttt aaaggagaaa agacagcaac agcatcagcc
    12781 tatgacctct atgtactaga agacgaacca cttccccaag tagggacctt cgatgtcatt
    12841 ttagatagtc aaaatcagtc tgtctgcatt gtcgaaatta caaaggtttc tgttgaactc
    12901 ttcaatcaag tttctgcgca acatgccttt aaggaaggtg agggagacaa atcacttgcc
    12961 tattggcgcc aggttcatga ggactttttc acagactgtt tgggtgaagt agggctgact
    13021 tttacacctg aaagcaaggt tgttttagaa gaatttcgca aggtctaccc actgtagact
    13081 atttagaagg aagaaagttt tggaaatcgc tgtccaatcc ttttttctca agcaaaatat
    13141 gatataataa gtttgtttga agaagagcag tagctcttaa acttagaata ggagaaaact
    13201 atgcaagcag ttgaacattt tattaagcaa tttgttcctg aacattatga tttattttta
    13261 gatttgagtc gtgagaccaa gactttttct gggaaagtga ccatcactgg tcaagcacag
    13321 agtgaccgca tctccctcca ccaaaaagac ttggaaatca cctctgtaga agttgcaggt
    13381 caagctcgtc catttacagt tgaccatgac aatgaagccc ttcatatcga attggctgag
    13441 gctggtcaag ttgaattggt tcttgccttt tctggtaaaa ttacagacaa catgacaggg
    13501 atttaccctt cttattatac agttgatgga gtcaagaagg aggtcttgtc tactcagttc
    13561 gagagccatt ttgcgcgcga agctttccca tgtgtggatg agcctgaagc caaagcaact
    13621 tttgacctct ctcttcgctt tgaccaagca gaaggtgaat tggccttgtc aaacatgcca
    13681 gaaatcgatg ttgaaaaccg taaggaaaca ggtatctgga agtttgagac aacacctcgc
    13741 atgtcttctt acttgttggc ctttgttgct ggtgatttgc aaggggtgac cgctaaaact
    13801 aaaaatggta ccctggtagg tgtctactca accaaagcac atccactttc aaatcttgat
    13861 ttctcactgg atatcgctgt tcgctctatc gagttttacg aagattacta tggagttaag
    13921 tacccaattc ctcaatctct ccacatcgcc cttcctgact tctcagctgg tgctatggaa
    13981 aactggggtc ttgtgaccta ccgtgaagtt tacttggttg tcgatgagaa ctctacattt
    14041 gctagccgtc aacaagttgc ccttgttgtg gcccatgaat tggctcacca atggtttggg
    14101 aacctcgtga ctatgaaatg gtgggatgac ctttggctca atgaaagttt cgctaatatg
    14161 atggaatacg tctgtgtgga taccatcgaa ccaagctgga atatctttga agatttccaa
    14221 acaggtggag tacctcttgc tcttgaacgt gacgctactg atggcgttca gtctgtccac
    14281 gtcgaagtta aacatccaga tgaaatcaat acactctttg acggcgctat cgtctatgcc
    14341 aaaggaagcc gtctcatgca catgcttcgc cgttggctag gagatgctga ttttgctaaa
    14401 ggtttgcacg cctactttga aaaacaccaa tacagcaaca ccattggtag tgacctttgg
    14461 gatgcccttg gtcaagcgtc aggacgtgat gtcgcagcct tcatggattc ttggttggaa
    14521 cagcctggtt acccagttct tactgttaaa gttgaaaatg atgtcttgaa gatttcacaa
    14581 aaacaattct tcatcggtga gaacgaagac aagaaccgtc tctgggtggt gcccctcaat
    14641 agcaactgga aaggcttgcc tgatacactc gaaactgaaa gtatcgaaat ccctggctac
    14701 gcagctcttc ttgctgaaaa tgaaggagct cttcgtctca acactgaaaa tactgcccac
    14761 tatattaccg actatcaagg agacttgtta gaagctgttc ttgctgagct agagacactt
    14821 gataacacaa gcaaactgca aattgttcaa gaacgtcgtt tgttggctga ggcagggcac
    14881 attgcttatg cagacttgct tccagttctt gataaacttg ctaaggaaga gtcttatctg
    14941 gtggtttcag ctgtttctca agtgatttca gcccttgagc gctttattga tgaaggaacg
    15001 gatgctgaaa cagccttcaa aggactggtt gctaaattgg ctcgtcataa ctatgaccgt
    15061 cttggttttg aagctaaaga cggagaatca gatgaggatg aattggttcg tcagctggct
    15121 gtttcgatga tgattcgctc aaatgatgca gaagctagtc aagtcgctag ccaaatcttc
    15181 gcaacacaca aggagaatct tgcaggactc ccagcagcta ttcgttcaca agttctgatt
    15241 aatgagatga aacatcatga gactaaagac ttgttagcac tttatcttga tacttatact
    15301 cacgcaacag atgctgtctt taaacgccag ttggcagcag ctcttgcata cagtacagat
    15361 gcggataata tccaaaactt gattacttct tggaaggaca aatttgtggt caaaccacag
    15421 gacttgtctg cttggtatta ccaattccta gctcatcaag caactcagaa aacagcttgg
    15481 tcttgggcgc gtgaaaactg ggcttggatt aaggcagccc ttggaggaga tatgagcttt
    15541 gatagctttg ttatccttcc tgctcatgta tttaagactc agcaacgctt ggcggaatac
    15601 aaggagttct ttgagccgca actttctgac cttgctctta gccgtaacat cggtatggga
    15661 atcaaggaaa ttgcagcgcg tgttgacttg attagccgtg aaaaagctgc agtcgaagca
    15721 gttgttcttc aatacggaaa tgcataaata agcctaaaat aaaaagaaaa ctcagctatc
    15781 tcatgtaaaa tgcagagagt tgagtttttt ttaaggcaaa tttggtataa tagttttaat
    15841 aaggaggagt ttctcatgat aaaaatctta ttggttgagg atgacctagg tctgtcaaat
    15901 tcagtatttg actttttaga cgattttgcg gatgttatgc aggtatttga tggagaagaa
    15961 ggtctctacg aagctgagag tggtgtctat gacttgattt tgctggattt gatgttgcca
    16021 gaaaaaaatg gtttccaagt cttaaaagaa ttgcgtgaaa agggaattac gacaccagtt
    16081 ctgattatga ctgccaagga aagtttggat gacaagggac atggatttga actgggagcg
    16141 gatgattatc tgaccaaacc tttctaccta gaagaactta aaatgcggat tcaggccctt
    16201 ctcaaacgtt cagggaagtt taatgaaaac accttgactt atgggaatat cgtggttaat
    16261 ttatcaacca ataccgttaa agttgaagat actcctgtcg aattgctggg gaaagagttc
    16321 gatttactag tttatttcct tcaaaatcaa aatgtgattt tgcctaagac gcagattttt
    16381 gaccgtctat ggggatttga tagtgataca acgatttcgg ttgtcgaagt ctatgtttca
    16441 aaagtccgta agaaattaaa gggaaccact tttgcagaga atttgcaaac tttgcgtagt
    16501 gttgggtatc ttttaaaaga tgttcagtaa actaaaaaaa acatggtatg cggatgactt
    16561 tagttatttt atccgcaact tcggtgtctt caccctgatt ttttctacaa tgactctgat
    16621 tattttacaa gtcatgcatt cgagtcttta tacttcggtg gacgataagc ttcatggact
    16681 gagtgaaaat cctcaagcag ttattcagct ggctataaat agggcaacag aagagattaa
    16741 agatttagaa aatgctaggg cggacgctag taaagtagaa ataaaaccta atgtcagttc
    16801 caatacggaa gtcattctct ttgataaaga ctttactcaa cttctttctg gaaatcgatt
    16861 tttgggcttg gataagatta agttagaaaa gaaagaacta ggacatatct accagattca
    16921 ggtttttaat agctatgggc aggaagaaat ctatcgtgtg attttgatgg agaccaatat
    16981 tagttcggtt tcaaccaata tcaagtatgc tgctgtcttg attaatacca gtcagttgga
    17041 acaggctagt caaaagcatg agcaattgat tgtggtcgtg atggctagtt tctggatttt
    17101 gtctttactt gccagtctct atctagctag ggtcagtgtt aggcccctgc ttgagagtat
    17161 gcagaagcaa cagtcttttg tggaaaatgc cagtcatgag ttacgaactc cactcgcagt
    17221 tttgcaaaat cgcttagaga ccctttttcg taagccagaa gctaccatta tggatgtgag
    17281 cgaaagcatt gcatcgagtt tggaagaagt ccgaaatatg cgttttttaa cgacaagctt
    17341 gctgaactta gctcggagag atgatgggat taagccggag cttgcagaag ttccaactag
    17401 cttttttaat acaactttca caaactacga gatgattgct tcggaaaata atcgtgtctt
    17461 ccgttttgaa aatcgtatcc atcgaacaat tgtcacagat cagcttcttc tgaaacaact
    17521 gatgaccatt cttttcgata atgccgtcaa gtatactgag gaggatggtg aaattgattt
    17581 tcttatctcg gcgaccgatc gcaatcttta tttacttgtt tctgataatg gaatcggtat
    17641 ttcgacagaa gataaaaaga aaatttttga ccgtttttat cgagtagaca aggctagaac
    17701 tcggcaaaaa ggtggttttg gtttaggatt atccctagcc aagcaaattg tagatgctct
    17761 aaaaggaact gttactgtca aagataataa acccaaggga acaatctttg aagtgaagat
    17821 tgccattcag acaccatcta aaaagaaaaa ataaaaatat cgctccaact ggggcgatat
    17881 tttggattta tcttctacgt tttcgtttga taatagaccg ttgaactttt aaaacaagta
    17941 agctgaatcc gattgctgcg gcaaaggcaa gagcagttga taattttaat gctaaaaaga
    18001 taaaactaaa gatagcaata cagatacaaa aaacagcgat attaataaaa aataggattt
    18061 ccttgagatt ggcatcagat tgcgcttcag gtgtataagc ttggtaatga ggaagctgct
    18121 ggtttaattc ttcttgatag tctacctcat aggattgtaa ttttcttacg ggcataattc
    18181 tctccttaac agtacatacc tattttatca ttttttcggc agagaattat tacagaaagg
    18241 ttacaaaaag aataaagtcc cttttcattt tcaaagcatg gatgattttg gagaaatgtg
    18301 gtataatttt tcttatggaa aagattgtca ttacagcaac tgctgaaagt attgaacaag
    18361 ttgaacaact actcgaagct ggcgtagacc gtatctatgt cggtgagaaa gattttggcc
    18421 ttcgtctgcc aacgaccttt agttatgacc aattacgtga aatcgctaag ttggttcatg
    18481 atgctggtaa ggaattgctc gttgcggtca atgctctcat gcaccaagat atgatggacc
    18541 gtatcaagcc tttcttagac ttcttggaag aaatcaagac agactatatt acgattgggg
    18601 atgcaggcgt cttttacgta gttaaccgcg atggttattc atttaagacc atctacgatg
    18661 cttcaaccat ggtaactagc agtcgtcaga ttaacttctg gggacaaaag gctggcgcat
    18721 ctgaggctgt tttggcgcgt gaaattccat cagctgaact tttcaaaatg ccagagattt
    18781 tggaaattcc tgctgaagtt ttggtttacg gtgctagcgt catccatcat tctaaacgtc
    18841 cactcttgca aaactactat aactttacac atatcgatga tgaaaagacg cataaacgtg
    18901 acctcttctt ggctgagcca agtgatccag agagccacta ttccattttt gaagataatc
    18961 atgggaccca tatctttgcc aacaatgacc ttgatttgat gatcaaatta acagaattgg
    19021 tggagcatgg ctttactcgc tggaaactag aagggctcta cactcctggt cagaactttg
    19081 ttgagattgc aaaactcttt atccaagcgc gtagcttgat tcaagagggc aactttagcc
    19141 atgaccaagc cttcttgctg gatgaagaag ttcgtaaact tcaccctaaa aaccgtttcc
    19201 ttgatacagg attttatgac tacgatcctg acatggttaa ataaaataca tgattcgttg
    19261 agagaaggaa gatgaaaaca tttcttctct caatttttcg tatttcttca ctattttaaa
    19321 aaatcagcag gctagaatgc tctattcgat gggattttta agaaaagtag tgttcttgag
    19381 tttgaaaatt atcctatgtt tgcaggtgcc aaatggccct ttttttggta taatttttta
    19441 taatgaaaac gattggtaat cgctatgttg tggtggattt agaggcaact agcacaggta
    19501 gtaaggctaa aattatccaa gtgggaattg tcgtgattga ggacggagaa atcgtcgatc
    19561 actatacgac ggatgtcaat ccacatgaac ccttggatgc tcatatcaaa gaactgacag
    19621 gattgacaga ccaacgtctg gcgcaagcac ctgatttttc gcaagttgcc agaaaaatat
    19681 ttgacttggt ggaggatggg atttttgtag cccataatgt tcagtttgat gctaatctct
    19741 tggcggaaaa tttatttttt gaaggctatg agctaagaaa ccctcgtgtt gatacggtcg
    19801 aattggccca ggtctttttc cctgaactgg aaaaatatag cttgccgatt ttgtgtcgag
    19861 aattaggaat tcctcttaaa cacgcacaca cagccctttc agatgcccaa gctacagcag
    19921 aattacttct ttttttacgg gaaaagatga ctcagcttcc taaaggtctc ttggaacgct
    19981 tgctggaaat ggctgacgct ctcctatatg agtcctacct ggttattgag gaaacttatc
    20041 gcaaccaatc tatcctgagt tctccagact tggtccaagt tcaaggtctg tattttaaga
    20101 aaacggcagc ttctctggag ccacgaaaac tatctcaaga cttttctaaa aatatttctc
    20161 tgttgaacct tgaagtgagg gaggaacaag aaagttttgc taaagaggtt ggcttgctat
    20221 tgaaagatga acctgtctct ctgattcaag cgccgacagg gattgggaaa acctatggct
    20281 atctcttacc cgctttatct caatccaaag agcgacaaat tgttcttagt gttccgacaa
    20341 agattcttca aaatcaaatc atggaagaag aaggtaaacg cctcaaggaa gtgttccata
    20401 cagatattca tagcttaaag ggaccacaaa attatctgaa gttggatgcc ttttatcatt
    20461 ccttgcagga aaatgatgaa aatcgcttat ttagacgctt taaaatgcaa gtcttggtct
    20521 ggcttactga gacagagaca ggagatttgg atgaaatcgg gcaactctat cgttaccaac
    20581 attttctagc agaccttcgt catgatggga atttatcatc ccagagctta tttgtgacgg
    20641 aagatttttg gaaacgtagt caagaaaggg cagagacttg caagctttta gtgactaatc
    20701 atgcctatct cgtgaccaga cttgaagata atcctgaatt tgtcagtgac cgtttactga
    20761 ttattgatga agtccaaaag attttgttag ctctagaaaa tctgcttcaa gagacctacg
    20821 atatacaatc tattatcgat ttaattgata aggctttagt aggagaagaa aacagggttc
    20881 aacaacggat actagaaagt attcgctttg agtgtctcta cttgatagaa caatttcagt
    20941 ctggtaaatc taggaaaaat atcttagatt ctctggacaa tctccatcag tatttttcag
    21001 aattagaagt agaaggcttt gatgagctgg ttcgctattt tacagctgaa ggtgattact
    21061 ggcttgaagt aactgaaacg agtcaaaaga aaattcatat ttcttctaca aaatcaggcc
    21121 gtactcttct gtcctcttta cttcctgaga gttgccaagc catgggagta tcggctactc
    21181 ttgagattag tcagagggtt tctttggcag accttttagg ctatcctgaa gccaaatttg
    21241 tcaagattga atctcgggga aaacaggaac aagaagtggt tatggtcaaa gatttccctc
    21301 tggtaacaga aacctcctta gaagtctatg ccagagaggt agctgcttta ctagtggaaa
    21361 ttcaagcttt ccagcaaccg attttggttc tctttaccgc taaagacatg cttctagcag
    21421 tatcggattt acttacagtt agccacttgg cccagtataa aaatggggat gttcatcagc
    21481 taaagaaacg ctttgaaaaa ggtgaacaac aaatcttgct tggtgcagca agtttctggg
    21541 agggagttga tttttcaagc catccttttg tgattcaagt tgtaccgagg cttcctttcc
    21601 aaaatcctca agaacccttg acgaaaaaga ttaatcaaga actgaatcaa gaagggaaaa
    21661 atgcctttta tgattatcaa ttgccaatgg ccattattcg tttaaaacag gctttgggaa
    21721 gaagtatgag acgtgaatac caacgttcct taactcttat tttggatagg agaatcatcg
    21781 gaaaacgata cggcaaacaa atagtagcat ctctagcaga agaagcgact gttaaaacca
    21841 tctctcgatc cgaagttgac gaggctattg atagattttt taatgaactt tgataaatag
    21901 tattgtatga aagtataagg ttagtatata tgaaacgttc tctcgactct agagtcgatt
    21961 atagtttgct cttgccagta ttttttctac tggtcatcgg tgtggtggct atctatatag
    22021 ccgttagtca tgattatccc aataatattc tgcccatttt agggcagcag gtcgcctgga
    22081 ttgccttggg gcttgtgatt ggttttgtgg tcatgctctt taatacagaa tttctttgga
    22141 aggtgacccc ctttctatat attttaggct tgggacttat gatcttgccg attgtatttt
    22201 ataatccaag cttagttgca tcaacgggtg ccaaaaactg ggtatcaata aatggaatta
    22261 ccctatttca accgtcagaa tttatgaaga tatcctatat cctcatgttg gctcgtgtca
    22321 ttgtccaatt tacaaagaaa cataaggaat ggagacgcac ggtttcgctg gactttttgt
    22381 taattttctg gatgattctc tttaccattc cagtcctagt tcttttagca cttcaaagtg
    22441 acttggggac ggctttggtt tttgtagcca ttttctcagg aatcgtttta ttatcagggg
    22501 tttcttggaa aattattatc ccagtatttg tgactgctgt aacaggagtt gctggtttct
    22561 tagctatctt tattagcaag gacggacgag cttttcttca ccagattgga atgccgacct
    22621 accaaatcaa tcggattttg gcttggctca atccctttga gtttgcccaa acaacgactt
    22681 accagcaggc tcaagggcag attgccattg ggagtggtgg cttatttggt cagggattta
    22741 atgcttcgaa tctgcttatc ccagttcgag agtcagatat gatttttacg gttattgcag
    22801 aagattttgg ctttattggc tctgtcctgg ttattgccct ctatctcatg ttgatttacc
    22861 gtatgttgaa gattactctt aaatcaaata accagttcta cacttatatt tccacaggtt
    22921 tgattatgat gttgctcttc cacatctttg agaatatcgg tgctgtgact ggactacttc
    22981 ctttgacggg gattcccttg cctttcattt cgcaaggggg atcagctatt atcagtaatc
    23041 tgattggtgt tggtttgctt ttatcgatga gttaccagac taatctagct gaagaaaaga
    23101 gcggaaaagt cccattcaaa cggaaaaagg ttgtattaaa acaaattaaa taaggagaaa
    23161 atcatggtaa aagtagcagt tatgttagct cagggctttg aagaaattga agccttgaca
    23221 gttgtagatg tcttgcgtcg agccaatatc acatgtgata tggttggttt tgaagagcaa
    23281 gtaacgggtt cgcatgcaat ccaagtaaga gcagatcatg tctttgatgg agatttatca
    23341 gactatgata tgattgttct tcctggaggt atgcctggtt ctgcacattt acgtgataat
    23401 cagaccttga ttcaagaatt gcaaagcttc gagcaagaag ggaagaaact agcagccatt
    23461 tgtgcggcac caattgccct caatcaagca gagatattga aaaataagcg atacacttgt
    23521 tatgacggcg ttcaagagca aatccttgat ggtcactacg tcaaggaaac agtagtggta
    23581 gatggtcagt tgacaaccag tcggggtcct tcaacagccc ttgcctttgc ctacgagttg
    23641 gtggagcaac taggagggga cgcagagagt ttacgaacag gaatgctcta tcgagatgtc
    23701 tttggtaaaa atcagtaaaa cgggagttat tctctcgttt tttatgtgga aaactcaggg
    23761 aaatcatcgc ttttttcata aaaaaatgct ataatgaagg gtatgaaata tcacgattac
    23821 atctgggatt taggtggaac tttactggat aattatgaaa cttcaacagc tgcatttgtt
    23881 gaaacattgg cactgtatgg tatcacacaa gaccatgaca gtgtctatca agctttaaag
    23941 gtttctactc cttttgcgat tgagacattc gctcccaatt tagagaattt tttagaaaag
    24001 tacaaggaaa atgaagccag agagcttgaa cacccgattt tatttgaagg agtttctgac
    24061 ctattggaag acattttaaa tcaaggtggc cgtcattttt tggtctctca tcgaaatgat
    24121 caggttttgg aaattttaga aaaaacctct atagcagctt attttacaga agtggtgact
    24181 tctagctcag gctttaagag aaagccaaat cccgaatcca tgctttattt aagagaaaag
    24241 tatcagatta gctctggtct tgtcattggt gatcggccga ttgatatcga agcaggtcaa
    24301 gctgcaggac ttgataccca cttgtttacc agtatcgtga atttaagaca agtattagac
    24361 atataagaaa aaggaataag atgacagaag aaatcaaaaa tctgcaggca caggattatg
    24421 atgccagtca aattcaagtt ttagagggct tagaggctgt tcgtatgcgt ccagggatgt
    24481 acattggatc aacctcaaaa gaaggtcttc accatctagt ctgggaaatt gttgataact
    24541 caattgacga ggccttggca ggatttgcca gccatattca agtttttatt gagccagatg
    24601 attcgattac tgttgtggat gatgggcgtg gtatcccagt cgatattcag gaaaaaacag
    24661 gccgtcctgc tgttgagacc gtctttacag tccttcatgc tggaggaaag ttcggcggtg
    24721 gtggatacaa ggtttcaggt ggtcttcacg gggtggggtc gtcagtagtt aatgcccttt
    24781 ccactcaatt agacgttcat gtccataaaa acggtaagat tcattaccaa gaataccgtc
    24841 gtggtcatgt tgttgcagac cttgaggtgg ttggggatac agatagaact ggaacaacgg
    24901 ttcacttcat accggaccca aaaatcttta ctgaaacaac aacctttgat tttgataaat
    24961 taaataaacg gattcaagag ttggcctttc taaatcgcgg tcttcaaatt tctatcactg
    25021 ataagcgcca aggtttggaa caaaccaagc attatcatta tgaaggtggg attgctagtt
    25081 acgttgaata tatcaacgag aacaaggatg taatctttga tacaccaatc tatacagacg
    25141 gtgagatgga tgatatcaca gttgaggtag ccatgcagta cacaacaggt taccatgaaa
    25201 atgtcatgag tttcgccaat aatattcata cccatgaagg tggaacgcat gaacaaggtt
    25261 tccgtacggc actgactcgt gttatcaatg attatgctcg taagaataag ttactgaaag
    25321 acaatgaaga taatttaaca ggggaagatg ttcgcgaagg attaactgca gttatctcag
    25381 ttaaacaccc aaatccacag tttgaaggac aaaccaagac caaattggga aatagcgaag
    25441 tggtcaagat taccaatcgc ctcttcagtg aagccttctc cgatttcctc atggaaaatc
    25501 cacagattgc caaacgtatc gtggaaaaag ggattttagc tgccaaggct cgtgtggctg
    25561 ccaagcgtgc gcgtgaagtc acacgtaaaa aatctggttt ggaaatttcc aaccttccag
    25621 ggaaactagc agactgttct tctaataacc ctgctgaaac agaactcttc atcgtcgaag
    25681 gagactcagc tggtggatca gccaaatctg gtcgtaaccg tgagtttcag gctatccttc
    25741 caattcgcgg taagattttg aacgttgaaa aagcaagtat ggataagatt ctagctaacg
    25801 aagaaattcg tagtcttttc acagccatgg gaacaggatt tggcgcagaa tttgatgttt
    25861 cgaaagcccg ttaccaaaaa ctcgttttga tgaccgatgc cgatgtcgat ggagcccata
    25921 ttcgtaccct tcttttaacc ttgatttatc gttatatgaa accaatccta gaagctggtt
    25981 atgtttatat tgcccaacca ccaatctatg gtgtcaaggt tggaagcgag attaaagaat
    26041 atatccagcc gggtgcagat caagaaatca aactccaaga agctttagcc cgttatagtg
    26101 aaggtcgtac caaaccgact attcagcgtt ataaggggct aggtgaaatg gacgatcatc
    26161 agctgtggga aacaaccatg gatcccgaac atcgcttgat ggctagagtt tctgtagatg
    26221 atgctgcaga agcagataaa atctttgata tgttgatggg ggatcgagta gagcctcgtc
    26281 gtgagtttat cgaagaaaat gctgtctata gtacacttga tgtctaaaaa atagggagaa
    26341 gtagttccct tggtctaaaa aatatgatat aatcgttacg attgtttcaa gtaaaaaagg
    26401 agtttgatat gtctaatgga caactaattt atttaatggt tgcaattgca gtcattttag
    26461 ttctggctta tgtagtggca atctttctac gtaagcgaaa cgaggggaga ttagaggcgc
    26521 tagaagaaag aaaagaagaa ctatacaatc ttccagtaaa tgatgaagta gaagctgtaa
    26581 aaaatatgca cttgattgga caaagtcaag tggctttccg tgaatggaat caaaaatggg
    26641 tcgatttatc tctcaactct tttgccgata ttgaaaataa tctctttgaa gcagaaggtt
    26701 ataaccattc atttcgtttt ctcaaggcca gtcatcaaat tgaccaaatt gagagtcaaa
    26761 ttactttgat tgaagaagat attgcggcaa ttcgcaatgc tttggcagac ttagagaagc
    26821 aagaatctaa aaatagtggt cgtgttcttc atgctttgga tttatttgag gaacttcagc
    26881 atagagttgc tgaaaattca gaacagtatg gtcaagcctt ggatgaaatt gaaaaacaat
    26941 tagaaaatat ccaatctgaa ttttcacaat ttgtaacctt gaattcatcg ggtgaccctg
    27001 tggaagccgc agtgattttg gataatacag aaaatcacat tttggcctta agtcatattg
    27061 tggatcgtgt tccagccttg gttacgacgc tttctacaga attgccagat caattacagg
    27121 atttggaagc cggttatcgt aaactaattg atgctaatta tcattttgtt gaaacggata
    27181 ttgaagcgcg tttccacttg ctttatgaag cattcaagaa aaaccaagag aatattcgtc
    27241 agttggaatt ggataatgcc gaatatgaga atggacaggc acaagaggaa atcaatgcct
    27301 tgtatgatat ttttactcga gaaattgctg ctcagaaagt agtggaaaat ctacttgcaa
    27361 ctcttccaac ttaccttcaa catatgaaag agaataatac tttattggga gaagatattg
    27421 cacgtttgaa caagacctat ttacttcctg agacagctgc aagccatgtt cgtcgtattc
    27481 agacagaatt agagagtttt gaggcagcta ttgttgaggt aacttcaaat caagaagaac
    27541 caacccaagc ttattcagtt cttgaagaaa atcttgagga tttacaaact caactaaaag
    27601 atattgaaga tgagcaaatt tcagttagtg agcgcctgac acaaattgag aaagatgata
    27661 ttaatgcacg tcaaaaggcc aatgtttatg tcaatcgtct ccatactatc aagcgataca
    27721 tggaaaaacg caatctgcca ggtattccac aaactttctt gaagttattc tttacggcaa
    27781 gcaataatac cgaggattta atggttgagt tagaacaaaa aatgattaac attgaatctg
    27841 ttacccgagt tcttgaaatt gcaacgaatg atatggaagc tttagaaacg gaaacttata
    27901 atattgtaca atatgcaact ttgacagagc aactcttgca atattctaac cgctatcgct
    27961 catttgatga acgcattcaa gaagcattta acgaagcttt agatattttt gaaaaagaat
    28021 ttgattatca cgcttcattt gacaagattt ctcaagcatt ggaagtggca gagcctggtg
    28081 taaccaatcg ctttgttacc tcatatgaga aaacacgtga aacgattcgt ttttaataaa
    28141 agaaaaagat tttattgtgt gaggagcaga atcaaatctt tttctatagt tgtggggaga
    28201 tttacttcat tttctcctga gattgagttt ttacccagcc gatttatcca ccacttcaaa
    28261 acagtgtttt atactcttcg aaaatctctt caaatcacgt cagcgtcgcc ttaccgtact
    28321 caagtacagc ctgaggctag cttcttagtt tgctttttga ttttcattta gtattaaagt
    28381 gatttcgtca gtcttatctg cagcttcaaa tctgtacttt gaagtaactt ggtaaccgtc
    28441 caataacgaa gtctattgaa aaatctccag actagagaac tcacggatag ttcctaatct
    28501 ggagatttct tatttgcact tttcttgtac aactttagtc cacggtaaat aggcctctaa
    28561 aacctctttg tttacgagag ttttctcgtt tggaagacat tctagaagat aggatagata
    28621 tttctcgcta tttatactag act
//
LOCUS       DAVBBO010000026        27275 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ST1
            SAMEA2066453-rid20184263.denovo.026, whole genome shotgun sequence.
ACCESSION   DAVBBO010000026 DAVBBO010000000
VERSION     DAVBBO010000026.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2066453
            Sequence Read Archive: ERR351777
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 27275)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 27275)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980402.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980402.1
            Genome Coverage       :: 176x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:17:33
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,141
            CDSs (total)                      :: 2,104
            Genes (coding)                    :: 1,953
            CDSs (with protein)               :: 1,953
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 16S)
            partial rRNAs                     :: 1 (23S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 151
            CDSs (without protein)            :: 151
            Pseudo Genes (ambiguous residues) :: 0 of 151
            Pseudo Genes (frameshifted)       :: 73 of 151
            Pseudo Genes (incomplete)         :: 76 of 151
            Pseudo Genes (internal stop)      :: 40 of 151
            Pseudo Genes (multiple problems)  :: 32 of 151
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..27275
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2066453-rid20184263.denovo.026"
                     /strain="ST1"
                     /db_xref="taxon:1313"
     gene            228..1910
                     /locus_tag="VQU30_001104"
     CDS             228..1910
                     /locus_tag="VQU30_001104"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000656554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET2447224.1"
                     /translation="MKEAIIEWKDFSFRYETQQEPTLQGIDLTIYKGEKVLIVGPSGS
                     GKSTLGQCLNGIIPNIYKGQTYGEFLIKGQTAFDMSIYDKSHLVSTVLQDTDGQFIGL
                     SVAEDLAFALENDVTALDEMKGRVYKWAEKLDLLPLLDQRPQDLSGGQKQRVSLAGVL
                     IDESPILLFDEPLANLDPKSGQDIIELIDQIHKEEGTTTLIIEHRLEDVLHRPVDRIV
                     LINDGRILFNGSPDQLLATDLLTQNGIREPLYLTTLRQLGVDLVKEEQLANLDNMSIS
                     KGQVQLQNELVKETPELQSLFKLEDVSFSYDDRPILKSLHLDIKKGEKIAIVGKNGAG
                     KSTLAKAISSFIQTEGRYLWEKQDIKGDSVAERAERVGYVLQNPNQMISTNMIFDEVA
                     LGLRLRGVDEKEIETRVYETLKICGLYEFRNWPISALSFGQKKRVTIASILVLGAEII
                     LLDEPTAGQDQKNYTEIMEFLEELHRKGHTIVMITHDMQLMLDYSDRVLVMVDGELIA
                     DTVPASLLSDPELLVKANLKETSIFNLAKKLDVDPLDLTAFYKERREGCKLN"
     gene            1895..2725
                     /locus_tag="VQU30_001105"
     CDS             1895..2725
                     /locus_tag="VQU30_001105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter transmembrane
                     protein EcfT"
                     /protein_id="HET2447225.1"
                     /translation="MQAKLIGYQHRDTVIHRLSGAGKLLFFILVSLAAMISYDTRMLL
                     LIAIFSVFLLYLSEIRFKDVSFVAVFATVFAVLNVLMVYLFSPEYGVGLYGERSVIWQ
                     GIGVYTLTSQELFYLLNLAIKYLCTIPLAIIFLMTTHPSQFASSLNQIGVPYKIAYSV
                     SLTLRYIPDLQEEFFTIKMSQEARGMELSKKASLMQRIKGNLLIITPLIFSSLERIDT
                     IATAMELRRFGKEKKRTWYSYQALKKGDYITLLLATLFLVASLLLSLQNQGRFYNPWK
                     "
     gene            2918..3421
                     /locus_tag="VQU30_001106"
     CDS             2918..3421
                     /locus_tag="VQU30_001106"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000181367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (cytidine(34)-2'-O)-methyltransferase"
                     /protein_id="HET2447226.1"
                     /translation="MTNHIVLFEPQIPQNTGNIARTCAATNSPLHIIKPMGFPIDDRK
                     MKRAGLDYWDKLEIYFYESLEDFISQMKGKLYLISKFAEKVYSEVDLSTDEDHYFLFG
                     REDKGLPEDFMREHPEKALRIPMNDEHVRSLNVSNTVCMIVYEALRQQNFAGLELVHT
                     YEVDKLK"
     regulatory      3475..3709
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00050"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="FMN riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="flavin mononucleotide"
                     /db_xref="RFAM:RF00050"
     gene            3874..4437
                     /locus_tag="VQU30_001107"
     CDS             3874..4437
                     /locus_tag="VQU30_001107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HET2447227.1"
                     /translation="MTNTRRLSTIAILSAISFVLMYFDFPLLPAASFLKIEFSILPVL
                     VGLVVMDLPAALGVLLLRSLLKLLLNSQGVNTYIGLPMNIVALGVFVIVFALIWKKER
                     TTLRFLLGSLAGTIGLTVAMLVLNYVYAVPLYAKFANFDIGKILGLSNYLMTMVLPFN
                     LIEGVIFSVSFWLLYILLKPTLKHYER"
     gene            4451..5077
                     /locus_tag="VQU30_001108"
     CDS             4451..5077
                     /locus_tag="VQU30_001108"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001853067.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatase PAP2 family protein"
                     /protein_id="HET2447228.1"
                     /translation="MKGSFALLLFVILGYMVKFYPEMLVNFDQSIQTAIRGDLPDYLT
                     ILFRSLTRLIDIPVIITWVVIIAFVFYRKRWKIESFFMLGNLTLAGLLIVTFKNIYQR
                     PRPAILHLVEEKGFSFPSGHSLAVTLMVGTLIVILSQRIKDQVWRKIVQIVLGLYLVS
                     VLVSRVYLGVHYPSDVLASLCVGLGALFIEFPFYDKLRFQWRFKGKQK"
     gene            5189..6061
                     /locus_tag="VQU30_001109"
     CDS             5189..6061
                     /locus_tag="VQU30_001109"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000525616.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HET2447229.1"
                     /translation="MGMLLATRLKNKRKELKLSQKELAEGICEQGQISRMEQGKYSPG
                     SELLFQLSKRLKVSMDYFFEDTEVSSLENIDKFKELSKKFLDEREYESLHYIYELEKS
                     KRARLSAKDQIYLDWIDTLVQFCYLNHQTGAVAKLEKILLSLKKSDFYYLQLGNTLAN
                     FYFDMGQEDTYQELYQLLKENLQSLSVHHLEQLELMIKFRYNYCRYLWLNERTSEAIE
                     EITETIAICKRYNSSYRLADLYCLLGSISEGFAERDRILGFYQVSYQLYKHEENQRMM
                     LEIEKEMKLLESED"
     gene            6191..6328
                     /locus_tag="VQU30_001110"
     CDS             6191..6328
                     /locus_tag="VQU30_001110"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2447230.1"
                     /translation="MKRSQVVKRCILIALLLLFLLNVLSGSLSVTTRGVDPRPAYGVS
                     L"
     gene            6752..7666
                     /locus_tag="VQU30_001111"
     CDS             6752..7666
                     /locus_tag="VQU30_001111"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000781144.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ThiF family adenylyltransferase"
                     /protein_id="HET2447231.1"
                     /translation="MKLYQINDGIQIFESSNLEKIVIRNYRNGKKITIDHQPLLKKLL
                     LFLEVPKREEEILLYLPELSNKTLRSVLTNFMSLNIIHCQDTLIIHKKINILIIGLGT
                     TGGYLADGLCRSNINSKLFLLDKDRVDETNVGRQIYLRDDIGQYKVDVFKQKFSDKEI
                     KVFKIFINSKKDLEKICKREGIDLVIQCGDSPSPRELGKIVNTVCDTLQIPYIVNTGY
                     MSNVVPLPEFYYPNNRYNFNYKHQFSDEKLLFSQVLSKADYMVAIQSSFVMLMQIKNF
                     IFNEEPIYYGYRGYYNSVTLAWEVEKID"
     gene            7659..8672
                     /locus_tag="VQU30_001112"
     CDS             7659..8672
                     /locus_tag="VQU30_001112"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000170500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2447232.1"
                     /translation="MTKYLELDYSHSYILEGFRKNDAFIENHKECLDMLSDKIWRDNK
                     YMNTEKNISSPTRTILSRYTCNILSSLFIDISKNSIEKLIVTCENSDLNWIYNYYKSV
                     YNGVFCELRQLIQQYCKVKDKYEKWLFIKAIINQGIRQNEKEVVEFFLKQLKDNNQGI
                     FDYINSFSFYLLKFYSKDKSRIFLEEQLDIDDFLGSDKEDYARSLVFKNYASLLPDTS
                     ELKRNIMEKCLSQTPQDTDLWKEWFETYASQKEIRQKATEIFKHGYSDISLLKLVKIE
                     PDDTESLIRMIILCTSDLNSNIARYLISFLSDGRLKEFLELFVENFDFLNIIEGKTSE
                     INF"
     gene            8656..10248
                     /locus_tag="VQU30_001113"
     CDS             8656..10248
                     /locus_tag="VQU30_001113"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001236730.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET2447233.1"
                     /translation="MRLIFRIIRKDIILYSILTFLLSIAMVSEAFLMQFIVDSIKFGE
                     KKYVLISIFIVIFLILQTLLYYYQQFLTAVLSKKSAYEYRKLIFKNIQQTSLRLVTGE
                     KNDSILASLTTQIDQIEYNYFYSVYWGGYLLCQLVVAIVMSLYLNPLMSVLTICLSLP
                     NLFVALLFKNSLEQKQEELINETNSSIAVTQDLIEGITDWKIANREPNIFRVFESKTL
                     KLLEKQVKVEKFQYIVVSLNQLFSNVLYFGSWIVGGFLIIRGQLSLGSLIAFSQLLAR
                     ISYPVYASSDLLSKYISGKKIVEILSKEFIFSDESRNYPDEFNVISFEHYFTNIDEKD
                     MPFDKEFYKNKKYLLKGKSGSGKTTILKSILREYDDYSGIVKINGVDVRDIKESVLFD
                     NIAYVSQKPHLFSASLRDNLTLFSEDFTDNEIVEVLKFVELSKWANKDCLDMMLSNDD
                     IKLSGGEVKRVSLARALLMNKNILLLDEFSAGIDYETLLKIEKKLIDLDKMIIYVTHV
                     DIDRSGKQFDDVIDLDCLFISS"
     gene            10440..11343
                     /locus_tag="VQU30_001114"
                     /pseudo
     CDS             10440..11343
                     /locus_tag="VQU30_001114"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001091364.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
     gene            11361..11498
                     /locus_tag="VQU30_001115"
                     /pseudo
     CDS             11361..11498
                     /locus_tag="VQU30_001115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001853067.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatase PAP2 family protein"
     gene            11526..11867
                     /locus_tag="VQU30_001116"
     CDS             11526..11867
                     /locus_tag="VQU30_001116"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000867291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2447234.1"
                     /translation="MKVNIADLHPTQLYLSEKKLQDIQMLYQSAETIQVDPISILAFG
                     DCLLITDGHHRAYQALLAGRDTISAEWDRDGGDELYHLYAQACEERKIYSVFDLKNHI
                     LPLWIGMVSFF"
     gene            11840..12151
                     /locus_tag="VQU30_001117"
                     /pseudo
     CDS             11840..12151
                     /locus_tag="VQU30_001117"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000333655.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
     gene            12279..12866
                     /locus_tag="VQU30_001118"
     CDS             12279..12866
                     /locus_tag="VQU30_001118"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000418402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit delta"
                     /protein_id="HET2447235.1"
                     /translation="MELEVFAGQEKSELSMIEVARAILELRGRDHEMHFSDLVNEIQN
                     YLGTSNSDIREALPLFYTELNFDGSFISLGDNKWGLRSWYGVDEIDEEIIALEENDDD
                     EVAPKAKKKRVNAFMDGDSDAIDYNADDPEDEDAYEADPALSYDDENPDDEKNEVEAY
                     DAEINEIAPDDLGEDVDLNEDDDEFSDDDAETSEE"
     gene            13256..14863
                     /locus_tag="VQU30_001119"
     CDS             13256..14863
                     /locus_tag="VQU30_001119"
                     /EC_number="6.3.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000105234.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CTP synthase"
                     /protein_id="HET2447236.1"
                     /translation="MSTKYIFVTGGVVSSIGKGIVAASLGRLLKNRGLKVTIQKFDPY
                     INIDPGTMSPYQHGEVFVTDDGAETDLDLGHYERFIDINLNKYSNVTTGKIYSEVLRK
                     ERRGEYLGATVQVIPHITDALKEKIKRAALTTDSDVIITEVGGTVGDIESLPFLEALR
                     QMKADVGADNVMYIHTTLLPYLKAAGEMKTKPTQHSVKELRGLGIQPNMLVIRTEEPA
                     GQGIKNKLAQFCDVAPEAVIESLDVEHLYQIPLNLQAQGMDQIVCDHLKLDAPAADMT
                     EWSAMVDKVMNLKKQVKISLVGKYVELQDAYISVVEALKHSGYVNDVEVKINWVNAND
                     VTAENVAELLSDADGIIVPGGFGQRGTEGKIQAIRYARENDVPMLGVCLGMQLTCIEF
                     ARHVLGLEGANSAELAPETKYPIIDIMRDQIDIEDMGGTLRLGLYPSKLKRGSKAAAA
                     YHNQEVVQRRHRHRYEFNNAFREQFEAAGFVFSGVSPDNRLVEIVEIPENKFFVACQY
                     HPELSSRPNRPEELYTAFVTAAVENSN"
     gene            complement(15422..17053)
                     /locus_tag="VQU30_001120"
     CDS             complement(15422..17053)
                     /locus_tag="VQU30_001120"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004251733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Na/Pi cotransporter family protein"
                     /protein_id="HET2447237.1"
                     /translation="MSINWQEILFHFLGGLGLFLYSIKTMGDGLQQAAGDRLRFYIDK
                     YTSNPFFGVLVGIGMTALIQSSSGVTVITVGLVSAGLLTLRQAIGIVMGANIGTTVTS
                     FLIGFKLGNYALPMLFIGAVCLFFTKNRTVNNIGRILFGVGGIFFALNLMSGAMAPLK
                     DLQVFKDYMIELSKNPVLGVFVGTGLTLLIQASSATIGILQNLYAGNLIDLQGALPVL
                     FGDNIGITITAIIASLGANIAAKRVAGAHVAFNVIGTVVCVIFLVPFTVLIHWFEATL
                     NLAPEMTIAFAHGTFNITNTIVQFPFIGALAYFVTKIIPGEDEVVKYEPLYLDEHFIK
                     QAPSIALGNAKKELLHLGNYAAKAFDLSYKYIIDLDEKVAEKGHKTEEAINTIDEQLT
                     RYLIALSSEALSQKESEVLTNILDSSRDLERIGDHTEALLNLTDYLQRKNVEFSDAAL
                     KELEEVYRQTSDFIKDALDSVENNDIEKARSLVERHEAINKIERVLRKTHIKRLNKGE
                     CSTQAGVNFIDIISHYTRVSDHAMNLAEKVFAEQI"
     gene            17346..22325
                     /locus_tag="VQU30_001121"
     CDS             17346..22325
                     /locus_tag="VQU30_001121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000795197.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacterial Ig-like domain-containing protein"
                     /protein_id="HET2447238.1"
                     /translation="MKNPFFERRCRYSIRKLSVGACSLMIGAVLFAGPALAEETAVPE
                     NSGANTELVSGESEHSTNEADKQNEGEHARENKLEKAEGVAIASETASPASNEAATTE
                     TAEAASAAKPEEKASEVVAETPSAEAKPKSDKETEAKPEATNQGDESKPAAEANKTEK
                     EVQPDVPKNTEKTLKPKEIKFNSWEELLKWEPGAREDDAINRGSVVLASRRTGHLVNE
                     KASKEAKVQALSNTNSKAKDHASVGGEEFKAYAFDYWQYLDSMVFWEGLVPTPDVIDA
                     GHRNGVPVYGTLFFNWSNSIADQERFAEALKQDADGSFPIARKLVDMAKYYGYDGYFI
                     NQETTGDLVKPLGEKMRQFMLYSKEYAAKVNHPIKYSWYDAMTYNYGRYHQDGLGEYN
                     YQFMQPEGDKVPADNFFANFNWDKAKNDYTIATANWIGRNPYDVFAGLELQQGGSYKT
                     KVKWNDILDENGKLRLSLGLFAPDTITSLGKTGEDYHKNEDIFFTGYQGDPTGQKPGD
                     KDWYGIANLVADRTPAVGNTFTTSFNTGHGKKWFVDGKVSKDSEWNYRSVSGVLPTWR
                     WWQTSTGEKLRAEYDFTDAYNGGNSLKFSGDVAGKTDQDVRLYSTKLEVTEKTKLRVA
                     HKGGKGSKVYMAFSTTPDYKFDDADAWKELTLSDNWTNEEFDLSSLAGKTIYAVKLFF
                     EHEGAVKDYQFNLGQLTISDNHQEPQSPTSFSVVKQSLKNAQEAEAVVQFKGNKDADF
                     YEVYEKDGDSWKLLTGSSSTTIYLPKVSRSASAQGTTQELKVVAVGKNGVRSEAATTT
                     FDWGMTVKDTSLPKPLAENIVPGATVIDSTFPKTEGGEGIEGMLNGTITSLSDKWSSA
                     QLSGSVDIRLTKPRTVVRWVMDHAGAGGESVNDGLMNTKDFDLYYKDADGEWKLAKEV
                     RGNKAHVTDITLDKPITAQDWRLNVVTSDNGTPWKAIRIYNWKMYEKLDTESVNIPMA
                     KAAARSLGNNKVQVGFADVPAGATITVYDNPNSQTPLATLKSEVGGDLASAPLDLTNQ
                     SGLLYYRTQLPGKEISNVLAVSVPKDDRRIKSVSLETGPKKTSYAEGEDLDLRGGVLR
                     VQYEGGTEDELIRLTHAGVSVSGFDTHHKGEQNLTLQYLGQPVNANLSVTVTGQDEAS
                     PKTILGIEVSQEPKKDYLVGDSLDLSEGRFAVAYSNDTMEEHSFTDEGVEISGYDAQK
                     TGRQTLTLRYQGHEVNFDVLVSPKAALNDEYLKQKLAEVEAAKNKVVYNFASPEVKEA
                     FLKAIEAAEQVLKDHETSTQDQVNDRLNKLTEAHKALNGQEKFKEEKTELDRLTGEVQ
                     ELLAAKPNHPSGSALAPLLEKNKALVEKVDLSPEELATAKQSLKDLVALLKEDKPAVF
                     SDSKTGVEVHFSNKEKTVIKGLKVERVQASAEEKKYFAGEDAHVFEIEGLDEKGQDVD
                     LSYASIVKIPIEKDKKVKKVFFLPEGKEAVELAFEQTDSHVIFTAPHFTHYAFVYESA
                     EKPQPAKPAPQNKVLPKPTYQPASDQQKAPKLEVQEEKVAFHRQEHENAEMLVGEQRV
                     IIQGRDGLLRHVFEVDENGQRRLRSTEVIQEAIPEIVEIGTKVKTVPAVVATQEKPAQ
                     NTAVKSEEASKQLPNTGTADANEALIAVLASLGLASLALTLRRKREDKD"
     gene            22415..23611
                     /locus_tag="VQU30_001122"
     CDS             22415..23611
                     /locus_tag="VQU30_001122"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001096748.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglycerate kinase"
                     /protein_id="HET2447239.1"
                     /translation="MAKLTVKDVDLKGKKVLVRVDFNVPLKDGVITNDNRITAALPTI
                     KYIIEQGGRAILFSHLGRVKEEADKAGKSLAPVAADLAAKLGQDVVFPGVTRGAELEA
                     AINALEDGQVLLVENTRYEDVDGKKESKNDPELGKYWASLGDGIFVNDAFGTAHRAHA
                     SNVGISANVEKAVAGFLLENEIAYIQEAVETPERPFVAILGGSKVSDKIGVIENLLEK
                     ADKVLIGGGMTYTFYKAQGIEIGNSLVEEDKLDVAKALLEKANGKLILPVDSKEANAF
                     AGYTEVRDTEGEAVSEGFLGLDIGPKSIAKFDEALTGAKTVVWNGPMGVFENPDFQAG
                     TIGVMDAIVKQPGVKSIIGGGDSAAAAINLGRADKFSWISTGGGASMELLEGKVLPGL
                     AALTEK"
     gene            23747..24274
                     /locus_tag="VQU30_001123"
     CDS             23747..24274
                     /locus_tag="VQU30_001123"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000119911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aromatic acid exporter family protein"
                     /protein_id="HET2447240.1"
                     /translation="MSYFKKYKFDKSQFKLGMRTFKTGIAVFLVLLIFGFFGWKGLQI
                     GALTAVFSLRESFDESVHFGTSRILGNSIGGLYALVFFLLNTFFHEAFWVTLVVVPIC
                     TMLTIMTNVAMNNKAGVIGGVAAMLIITLSIPSGETILYVFVRVLETFMGVFVAIIVN
                     YDIDRIRLFLEKKEK"
     gene            24351..24707
                     /gene="glnR"
                     /locus_tag="VQU30_001124"
     CDS             24351..24707
                     /gene="glnR"
                     /locus_tag="VQU30_001124"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000659547.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional repressor GlnR"
                     /protein_id="HET2447241.1"
                     /translation="MKEKEFRRNMAVFPIGSVMKLTDLSARQIRYYEDQELIKPDRNE
                     GNRRMYSLNDMDRLLEIKDYISEGYNIAAIKKKYAEREAKSKKAVSQTEVRRALHNEL
                     LQQGRFASVQSPFGRG"
     gene            24744..26090
                     /gene="glnA"
                     /locus_tag="VQU30_001125"
     CDS             24744..26090
                     /gene="glnA"
                     /locus_tag="VQU30_001125"
                     /EC_number="6.3.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008808235.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I glutamate--ammonia ligase"
                     /protein_id="HET2447242.1"
                     /translation="MPITAADIRREVKEKNVTFIRLMFSDILGTMKNVEIPATDEQLD
                     KVLSNKVMFDGSSIEGFVRINESDMYLYPDLDTWTVFPWGDENGSVAGLICDVYTTEG
                     EPFAGDPRGNLKRALRHMEEVGFKSFNLGPEPEFFLFKLDENGDPTLEVNDKGGYFDL
                     APTDLADNTRREIVNVLTKMGFEVEASHHEVAVGQHEIDFKYDEVLRACDKIQIFKLV
                     VKTIARKHGLYATFMAKPKFGIAGSGMHCNMSLFDAEGNNAFFDPNDPKGMQLSETAY
                     HFLGGLIKHAYNYTAIMNPTVNSYKRLVPGYEAPVYIAWAGRNRSPLVRVPASRGMGT
                     RLELRSVDPMANPYIAMAVLLEVGLYGIENKIEAPAPIEENIYIMTAEERKEAGITDL
                     PSTLHNALKALTEDEVVKAALGDHIYTSFLEAKRIEWASYATFVSQWEIDNYLDLY"
     gene            complement(26186..26305)
                     /locus_tag="VQU30_001126"
     CDS             complement(26186..26305)
                     /locus_tag="VQU30_001126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001808898.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine synthetase"
                     /protein_id="HET2447243.1"
                     /translation="MPDIVFEIEFFHSDSLIFFYTSDDKSNSQKSQEDFSKNK"
     gene            26563..26700
                     /locus_tag="VQU30_001127"
     CDS             26563..26700
                     /locus_tag="VQU30_001127"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001067591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2447244.1"
                     /translation="MNPDRAEEYFCRGCQGENPEDIEFYDEQLQAEKVEALNIRLEVK
                     N"
     gene            26793..27275
                     /locus_tag="VQU30_001128"
                     /pseudo
     CDS             26793..27275
                     /locus_tag="VQU30_001128"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000187281.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
BASE COUNT         8594 a         4569 c         5792 g         8320 t
ORIGIN      
        1 aaccatacct acggcaaggc gaaactgacg tggtttgaag agattttcga agagtataaa
       61 atgatgggga aggctgggca actagtcttt ttcgatgttt atagattagt taggcaagta
      121 agctaggata ggaatctttt tggtgctaag attttaagag aagagactgc aagaagggct
      181 tgatttatga taaaatagaa gtctaagaag cgaatgaaga gagtaagatg aaagaagcta
      241 taattgagtg gaaggatttc tctttccggt atgaaacaca acaagaaccg accttgcaag
      301 ggatagactt gaccatttac aagggagaga aagtcttaat tgttggacca tctggatcag
      361 gtaaatctac cttgggtcag tgtttgaatg ggattattcc caatatttac aagggtcaga
      421 catatggaga atttttgata aagggtcaaa cagcctttga tatgagcatc tatgataagt
      481 ctcatctggt tagcacagtt ttgcaggata cagatgggca gtttattggc ttgtctgtgg
      541 cagaagattt ggcgtttgct ctggaaaatg atgtgacagc cctagatgag atgaaaggtc
      601 gtgtttataa atgggctgaa aagctggacc ttcttccttt actggatcag cgtcctcagg
      661 atttgtcagg tggacaaaag cagcgagtca gtctggctgg tgtcttgatt gatgaaagtc
      721 cgattctctt gtttgatgag ccactcgcca atctagatcc caagtcaggt caggatatta
      781 tcgaattgat tgaccagatt cataaggaag aggggacgac gactcttatt atcgagcacc
      841 gtttggagga tgttctgcat cgccctgtgg atcggattgt cttgataaac gatggtcgta
      901 tcctttttaa tgggagccct gaccagttgc ttgcgactga tttattgact caaaatggaa
      961 ttcgagaacc cctttatcta accactctcc gtcaattagg tgtggactta gtcaaggaag
     1021 aacagttagc gaatctggat aacatgtcta tctcaaaagg tcaggttcag ctgcagaatg
     1081 aactggtaaa agaaactcca gaattgcagt cactctttaa attagaggac gtgtctttct
     1141 cttatgatga tagaccgatt ttaaaatccc tacatttaga tattaaaaag ggtgaaaaga
     1201 ttgctattgt cggaaaaaat ggagcaggga aatcaactct agccaaggct ataagtagct
     1261 ttattcagac ggaaggacgc tatctttggg aaaaacagga tataaaaggc gattctgttg
     1321 cagagcgggc ggaacgagta ggctatgtgc tacaaaatcc taatcaaatg atttcaacca
     1381 atatgatttt tgatgaggtg gctctagggc tccgtttgcg aggtgtggat gagaaggaaa
     1441 ttgaaacgag agtctatgaa accttgaaaa tctgtggact ttatgaattc cgtaattggc
     1501 ctatttctgc cctgtcattt ggtcagaaaa aacgtgtcac cattgcttca attttggtct
     1561 taggagctga aattattctc ctagatgaac cgactgcagg tcaagatcag aagaactata
     1621 ctgagattat ggaatttctc gaagagttac atcgaaaagg gcataccatt gtcatgatta
     1681 cccatgatat gcaattgatg ctggattatt cagaccgagt ccttgtcatg gtggatggag
     1741 aattgattgc cgatactgtt ccagccagtc tgttgagcga tcctgagctg ttagtaaaag
     1801 ccaatctaaa agaaacctcc atctttaact tggctaagaa actagatgtg gatccactgg
     1861 atttaacggc attttacaaa gaaaggagag agggatgcaa gctaaattaa tcggttacca
     1921 gcatagagat actgtgattc atcgcttgtc aggagctggg aaacttctct ttttcattct
     1981 ggtatcattg gcggccatga ttagctatga taccagaatg ctcttgctga ttgccatctt
     2041 ttcagtcttt ctcctctatt tatcagaaat tcgctttaaa gatgtttcct ttgtagccgt
     2101 ttttgcgacg gtatttgccg ttttaaacgt tttgatggtc tatctctttt ctcccgagta
     2161 tggggttgga ctttatggag agagaagtgt gatttggcag ggaatcggtg tctacactct
     2221 aaccagccag gagctctttt atctgctaaa tttggccatt aagtatcttt gcaccattcc
     2281 tctggctatt atctttttga tgacaaccca tcctagtcag tttgcttcca gtttaaatca
     2341 aattggtgtg ccctataaga ttgcttattc tgtcagcctg accttgcgct atattccaga
     2401 tttgcaggaa gaattcttta ctatcaagat gtctcaggag gcgcgtggga tggaattatc
     2461 caagaaagct tctcttatgc aacgaatcaa aggcaatctg ctcattatta cgcccttgat
     2521 ttttagctcg ctagaacgca ttgataccat tgcgactgcc atggagcttc gccgctttgg
     2581 gaaagaaaaa aaacgcacat ggtatagtta tcaggccttg aaaaaaggag actatattac
     2641 cttgctcttg gcaaccttgt ttttagtagc tagtttacta cttagcttgc agaatcaggg
     2701 acgattttac aacccttgga aatagcttga aaaaattgaa aaaatcaagt cgtttctatt
     2761 gacaatgatt ctgaaagtgt tatactaaga aagtagtttc gctgatttac ttcaaacctg
     2821 ttgtgaggta agttaacgat gccttaacca cgctgtttgc tgagcttgac tccgggcagt
     2881 gtggctattt ttttgcaatg gtgaaaggaa gcaagtcatg acaaatcaca ttgtattatt
     2941 tgaacctcaa attccacaaa atacgggcaa tatcgcgcgt acttgcgctg cgaccaattc
     3001 tcccctccac atcatcaagc ctatgggctt tcctattgat gaccgcaaga tgaagcgggc
     3061 tggattggat tactgggata agctagagat ttatttttac gagagtttgg aagatttcat
     3121 atctcagatg aagggaaaac tctatctgat ttcgaaattc gcggaaaaag tctattctga
     3181 ggtggattta tcgactgacg aggaccatta ttttctcttt ggacgtgaag acaagggctt
     3241 acctgaagat tttatgcgag aacatcctga gaaggctctc cgtattccca tgaatgatga
     3301 acatgtccgc agtctcaatg tgtctaatac cgtctgcatg attgtctatg aggctcttcg
     3361 ccagcagaac tttgcaggtc ttgaactcgt ccatacctat gaagtggata aattgaaata
     3421 aaaaatgaaa atgaacaaaa tgcttgcgct tgcaagcgtt ttttgttatg ataaaagagt
     3481 cttcagggca gggtgtgatt cccgaccggc ggtgacttta actaggaaat gatcttttcc
     3541 ttttatactt tgttgacaag ctttgcctaa ccagaagtta tgcctacagc ttgtcgccta
     3601 gtctaaaaga aaaatctcta tttccttctc tttaaagaag tccgcgagcg caagctgatg
     3661 tggtgagatt ccacaaccga cagtatagtc tggatgggag aagacgaaag aatagctttg
     3721 tctgttttga tagatttata gccggattgt aaccacttgc tttgtttttc tttaatagag
     3781 taggagggaa cttttgggat ataaaaagtg agaatagata gaggaatcct ttccaacttc
     3841 ttctgatttt atagaaaatt ggaggaacct gttatgacaa acacacgtcg actttcgacc
     3901 attgcaattt tatcagccat ctcatttgtg ctgatgtact ttgactttcc gcttttacca
     3961 gcggcatctt tcctcaagat cgaatttagt atcttgccag tccttgtggg tctggtggtc
     4021 atggatttgc ctgctgctct aggagtgctc ttgcttcgct cactcttgaa attgcttctt
     4081 aacagccaag gagtgaatac ttacattggt ttgccgatga atatcgtagc tttgggagtt
     4141 tttgtcatcg tatttgcttt gatttggaaa aaggaacgga caacccttcg tttcctacta
     4201 ggctctctag ctgggactat tggtttaacc gtggctatgt tagttctcaa ctatgtttat
     4261 gctgttcctt tgtacgctaa gtttgctaac tttgatattg gaaaaatttt gggactttcc
     4321 aactacctaa tgaccatggt attacctttt aacttgattg aaggtgtaat cttttccgtt
     4381 tcattctggt tgttgtacat tctcttgaaa ccaaccttaa aacattatga aagataaaca
     4441 aacattttta atgaagggca gttttgccct tttacttttc gttattcttg gctatatggt
     4501 caaattttac cctgaaatgt tggtcaattt tgaccaatcg attcagactg ccattcgagg
     4561 agacttacca gattatttga ctattctttt tcgatccctc acacgtctga ttgatattcc
     4621 agtgattatc acttgggttg tcattatagc ttttgtcttt tatcgtaagc gatggaagat
     4681 agaaagtttc ttcatgctgg gaaatctgac tttggcaggt cttttaatcg tgacctttaa
     4741 aaatatctac cagcgcccac gaccagctat cttacatctg gtggaggaga agggattttc
     4801 cttcccaagt gggcattctc tggctgtaac gctgatggta gggactttga ttgttattct
     4861 tagtcagcgg attaaagatc aggtctggag aaaaatcgta caaatcgtcc ttggcctcta
     4921 cctagtcagt gtgctggtat caagagtcta tctgggagtt cattacccat cagatgttct
     4981 tgccagtctc tgtgtgggct tgggagccct gtttatcgag tttccctttt atgataagct
     5041 ccgcttccaa tggcgattta aaggcaaaca gaaatgatgg aaaagataaa aaattgtaca
     5101 aatacaaata gaaccatatg aaatatatac ttgaaacatg ttttggagtt tgatatattt
     5161 taataaataa agcaaggagg aagaaagtgt gggtatgtta ttagcgacac gcttaaaaaa
     5221 taaaagaaag gaattaaaat tatctcaaaa agaattagct gaggggattt gtgagcaagg
     5281 gcagattagc cgtatggagc aaggtaaata ctcacctggg tcagaattac tctttcaact
     5341 atctaagcga ttgaaggtga gcatggatta tttctttgaa gatactgagg tttctagttt
     5401 agaaaatatt gataagttta aagaattatc taagaaattt ttggatgaga gggaatatga
     5461 atctctccat tacatctatg aactggaaaa atctaaacgt gctcgtctat ctgctaaaga
     5521 ccagatttat ttggattgga ttgatacatt agttcaattc tgttatttaa atcatcaaac
     5581 aggggcagtt gcgaaactgg aaaaaatact gttatctctg aaaaaatctg atttttacta
     5641 tctacaactg ggaaatacct tggctaattt ttattttgat atggggcagg aagacacata
     5701 tcaggaactc tatcaacttt taaaagagaa cctccagtca ctatctgttc atcatttgga
     5761 acagttagaa ttgatgatta aattccgata taactattgt agatatttgt ggttgaatga
     5821 acgaacatct gaagctatag aagaaattac agaaacgata gctatttgta aaagatataa
     5881 tagtagttat cgattagcag atttgtattg tttattggga agtataagcg agggctttgc
     5941 tgaaagggat aggatactag gtttttatca agtatcttac cagctttaca agcacgaaga
     6001 gaaccagaga atgatgctag aaattgagaa ggaaatgaaa ttattggaaa gtgaagatta
     6061 agcaaaaaga tttgtattct tagataactt taatacatat tataaaaaaa ataaaaaaat
     6121 atcataaaaa ttattgacaa accaaaattg atgtgttaga atatcaccaa tagttaagga
     6181 ggtttagaag atgaaaagat ctcaagttgt caaacgatgt atattaattg ctttattgct
     6241 tctatttcta cttaatgtgt taagtggttc tttatctgta acaactagag gagttgatcc
     6301 aagaccagca tatggagttt cgctttaaag ttgtgcatag ttcttctttt atagacggag
     6361 agtttttctc aatagtaagt gattcaaatt ttgatggatg attttccatt aaattaagtg
     6421 attgcgaaaa ctttttgaaa tacattctct ttggatattg aaagtttgtt ttggattttt
     6481 ttatgaagct tatcttagct gttagattgg ggttttatgg gatttgtcct caccgggaaa
     6541 aaatcttaaa tctttgaaga aagaggtttt tatcttatgg ttagagatac atcagaagaa
     6601 attgaagtta ttgacttgtc ttctatgacc gtttcctact catctgttat gctaggaaac
     6661 tcttggatga cgtggaattg atttattaag atagattatt tggtttttac caaaaatctg
     6721 tctttttaat ttttaaagga ctaatggtga tatgaaacta tatcaaataa atgatgggat
     6781 acaaattttt gaaagtagta atcttgaaaa aatagtaatt agaaattata ggaatggtaa
     6841 gaaaataact atcgatcacc aaccattatt aaaaaaatta ctactattcc ttgaagttcc
     6901 taaacgtgaa gaagaaattc tattatatct tccagaatta tcaaataaaa cattacgaag
     6961 tgttttgacg aattttatga gtttaaatat aattcattgt caagatacat taataattca
     7021 caaaaaaata aacatattga taataggttt agggactacg ggtggatatc tggcagatgg
     7081 gttatgtcgt agtaatatta attcgaagct atttctttta gataaggatc gtgtagatga
     7141 gactaatgta ggtagacaga tttatttaag agatgatatt ggtcaatata aagttgatgt
     7201 atttaaacaa aagtttagtg ataaagaaat aaaggtattc aaaattttta ttaatagtaa
     7261 gaaagatttg gaaaagattt gcaaaaggga gggtatcgat ttggttatac aatgtggtga
     7321 ctccccttca cctcgagaat taggaaaaat tgtgaataca gtatgtgata ctctccagat
     7381 accttatata gttaacactg gctacatgag taatgtagtt cctttgccag aattttatta
     7441 tccaaataat agatacaatt ttaattataa gcatcaattt tcagatgaaa agttactgtt
     7501 ctcacaagtt ttgtctaaag ctgattatat ggtggcaatt caatcatcat ttgtaatgtt
     7561 aatgcaaata aaaaatttta tatttaatga agaacctatt tattatggtt ataggggata
     7621 ctataattct gtaacattag catgggaggt ggaaaaaatt gactaaatat ttagaattgg
     7681 attattctca ttcatatatt ttggaaggtt ttagaaaaaa tgatgcgttt attgaaaatc
     7741 acaaagaatg ccttgatatg ttatcagata agatttggcg agataataaa tatatgaata
     7801 cagaaaaaaa catatcatca ccgacacgaa caatcttatc acgctatact tgtaatattt
     7861 tatcgtcttt gtttattgat attagcaaaa atagcataga aaaattgata gtgacatgtg
     7921 aaaatagcga tcttaattgg atttataatt attataaatc ggtttacaat ggagtatttt
     7981 gtgaattgcg acaacttata caacagtact gtaaggtgaa ggataagtat gaaaagtggc
     8041 tttttataaa agctattata aatcaaggta ttcgtcaaaa tgagaaagaa gttgttgaat
     8101 tctttttaaa acaattgaag gataataatc aaggtatttt tgattacatc aatagtttta
     8161 gtttttatct attaaagttt tattcaaaag acaaatctcg cattttttta gaagagcagc
     8221 tagatataga tgattttttg ggatcagata aagaagatta tgctaggtct ttagttttta
     8281 agaattatgc ttctctattg cctgatactt ctgaattaaa aagaaatatt atggaaaaat
     8341 gtttaagtca aacacctcaa gatacagatt tatggaaaga atggtttgaa acttatgcca
     8401 gtcagaaaga gattagacaa aaagcaacgg aaatatttaa gcatggttat tcagatattt
     8461 cgttactaaa attagttaaa attgagcctg atgacactga gagtttaatc agaatgatta
     8521 tcttatgtac cagtgaccta aatagtaata ttgcaaggta tttgatttca tttttgagcg
     8581 atgggcgatt aaaagaattt ttggagttat ttgttgaaaa ttttgacttt ttgaatatta
     8641 ttgagggaaa aactagtgag attaattttt agaataatta gaaaagatat tatattatat
     8701 tctatattaa catttttgct atcaatagcg atggtaagcg aagcattttt gatgcaattt
     8761 attgttgatt caattaaatt tggtgaaaag aagtatgttt tgatttctat ttttattgta
     8821 atttttttga ttcttcagac tttattgtat tactatcaac aatttcttac agctgtatta
     8881 agtaaaaaat ctgcatatga gtaccgtaaa ttaattttta aaaatattca gcagacttct
     8941 cttaggcttg ttacaggtga aaaaaatgat agtattctag cttctttgac aacgcaaatc
     9001 gatcaaatag aatataatta tttttattct gtttattggg gtggatattt gctttgccaa
     9061 ttagtggtag ctatagttat gtcgctttat ctaaatccat tgatgtctgt attaaccatt
     9121 tgcttaagtc tccctaattt atttgtagca cttcttttta aaaactcctt ggaacaaaag
     9181 caagaagagc taattaatga gacaaattcc tcaatagcag ttactcaaga tttaattgag
     9241 ggaattactg attggaaaat tgcaaataga gaacctaata tatttagagt gtttgaaagc
     9301 aaaacattga agcttttaga gaagcaagtg aaggtagaaa aatttcaata cattgttgtt
     9361 agtttaaatc aattgttttc aaatgtttta tattttggta gttggatagt aggtggattc
     9421 ttgattatac gggggcaact ttcattaggg agtttgatag cgttctctca attattagca
     9481 agaatttctt accctgttta cgcttcttcg gatttattgt caaaatatat tagcggtaaa
     9541 aaaattgtag aaattctttc taaagaattt atattttcag acgaaagcag aaattatcca
     9601 gatgagttta atgttatttc atttgaacat tattttacaa acattgacga aaaggatatg
     9661 ccttttgata aagaatttta caaaaataaa aaatatttgt tgaaagggaa aagtggtagt
     9721 gggaaaacaa caattttaaa atcgatttta cgagagtatg atgattatag tggaattgta
     9781 aaaattaatg gggtagatgt tagggatata aaagagagtg ttctttttga caatatagct
     9841 tatgtttccc aaaaacctca cttgttcagc gcaagtctta gagacaacct gacattattt
     9901 tctgaagact tcactgataa tgagatagtt gaggttttaa aatttgttga attatctaaa
     9961 tgggctaata aagattgctt ggatatgatg ctttcaaatg atgatataaa attatcagga
    10021 ggggaggtca aaagggtttc tttagctcga gccttattga tgaataagaa tattctgtta
    10081 ttggatgagt tctctgctgg gattgattat gaaacattgt taaaaataga gaagaaactc
    10141 attgatttgg ataagatgat tatttacgtg acgcatgtgg atatagatag atccggcaaa
    10201 cagtttgatg atgtcattga tttggattgt ctttttatat cctcgtgaca tgagagttga
    10261 gtcagttgaa ttattttgtc actctgttta gttcttgttg gtagtgtcag gtaatctttg
    10321 ttaatttttc aggaagtcta ttgaaatatc ctcttggtta tatattacga ggagtaatta
    10381 atggatattc tcgagaattc aatacaacaa tttgattcta aagttaagta tgtttcttta
    10441 tttgcggaat caatctttta tcagatacca tgagctattt tgcaggtgct atgatttctc
    10501 ctttgtatgt gaggattatc ggagatgata tgacagatgc tatgggggtt agacaggcaa
    10561 ctgctggtgt agttaatatt ctcagcaacc ttataggggg agttttgatt gggggtcatc
    10621 agtcttcaga tgtttgtagg tttgaatgct ttgacctttc tttttgcact gttgggtgtg
    10681 gtgtttattc gtacttcttt gagagatatt gaggaacaga tggaggttag taaaagatta
    10741 gccgcaaaat cttttggaga gcatttcctc cattcaatga agatattgtc aagttttcca
    10801 gccatcatca aattaatatt cattgcagct atgaaccaag tgattttaag cattattatc
    10861 cctttaacga ctttgatgtt aatccatcat ccatttatct tctttgacac tgggaaatcc
    10921 attgcagcat tgtcagtggt tattttttca ggaacgattg tgggaagttt tttgagtgga
    10981 ggtatcctaa aaaatattcc cataaaaatg attgtctact ttgaagaaat tatgcatctc
    11041 tgtattctct tttcttggtt gaccaatcat ttcctccttt tattggtagt tgtcttctta
    11101 tgcgcagttg cagtaggaat gatggggcct cggattttca accttgtatt ctcgatggtt
    11161 ccagaagaag tcatgggaac catccagtca gtgcttggag tattcaatgt tgttgtacca
    11221 ggaattctta gcatgctcat cgttgcctta gcgagtgcta caaacctaaa aatcacagtg
    11281 cttccacttt ttatttttgt attgactgcc ttagcaattg tgaaagcaat gaaaatagag
    11341 taatagtagt atgaactact gtctcttttt gggtgggagt tcattaccca tcagacgtcc
    11401 ttgccagtct ctgtgtgggc ttgggagttt tgtttatcga gtttcccttc tatgacaagc
    11461 tccgcttcca atggcgattt aaaggcaaac agaagtgagt atcgaattcc cttgaggaga
    11521 aagaaatgaa agtcaatata gcagatcttc atccgactca actatattta tcagaaaaga
    11581 agttgcaaga tattcagatg ctttaccagt cggcagaaac aatccaagtc gatccaatca
    11641 gtattcttgc ctttggagat tgtttgctga ttacagatgg gcatcacagg gcttatcagg
    11701 ctttattggc aggtcgggat acgatttctg ctgagtggga tagagatggt ggtgatgaac
    11761 tatatcatct ctatgcgcaa gcttgcgagg aaagaaagat ttactctgtt tttgatttaa
    11821 aaaatcatat cttacctctt tggatcggca tggtgagctt tttttgattg aagtcaagga
    11881 gaagggagaa tggtttccaa ttggggatat tacactatct caggataatc tccccattgt
    11941 gattgggaat tccgcttacc aacatcgagg acttggaaaa aagattctaa gtgctttgat
    12001 tgaattggct cgagtaaaag gatggaaaga attgagagtc aaggaaatct acacctacaa
    12061 tcatgcttct aggaggtgtt tcaagtcgct tggatttgtg gaaaatggag caacagaaaa
    12121 aggaaggagt tttatattgg aattagtcta atcctgccac tttctccccc ttaacctttg
    12181 actattccgc aaaattatcg taaaataaag agtaaatgat aaaatgaggt cagagtctgt
    12241 tcgctctgac gatagtagta taaatgagga gaaacgcttt ggaattagaa gtatttgctg
    12301 ggcaagaaaa aagtgaacta tctatgattg aggtagcgcg tgctatatta gaacttcgtg
    12361 gtcgcgatca tgagatgcat tttagcgatc ttgtaaacga aattcaaaac taccttggaa
    12421 catcaaacag cgatatccgc gaagctttgc ctctgttcta cacagagttg aactttgacg
    12481 gtagcttcat ctcacttggg gacaacaaat ggggtcttcg ttcatggtat ggtgtggacg
    12541 aaatcgacga agaaatcatc gctcttgaag aaaatgacga cgatgaagta gcaccaaaag
    12601 ctaagaaaaa acgtgtcaat gcctttatgg atggtgattc agatgccatt gactacaatg
    12661 cagatgatcc agaagacgaa gatgcatacg aagcagatcc agctctttca tacgatgatg
    12721 aaaatccaga tgatgaaaaa aatgaagtgg aagcttatga tgcagaaatc aacgaaatcg
    12781 ctccagatga cttgggagaa gatgtggatc tcaacgaaga cgacgacgag ttttcagatg
    12841 acgacgctga aaccagcgag gaataagagt tagctattga caattatcct atttttaggt
    12901 atcatattgt ttgggcacct cttttagagg tcggggctcc ctagttctta gggagctatt
    12961 tttgtttttt caagaagtta tcttcttgta ttttatactc aatgaaaatc aaagagcaag
    13021 ctaggaaact ggccgtaggc tgctcaaaac actgttttga ggttgtagat aagactgaca
    13081 aagtcaggaa cacatatcta cggcaaggcg acgttgacgc ggtttgaaga gattttcgaa
    13141 gagtattagt tgtgaatctg gtgcagtcgt cccagattat tcttattagt agggtcttgt
    13201 tttctatatc ccctcgtagt taacaagacc ttgagcattt tagaaagagg aatctatgtc
    13261 tacgaaatat atttttgtaa ctggtggtgt ggtatcgtct attgggaaag ggattgtggc
    13321 agcgagtcta ggccgtctct tgaaaaatcg tggtctcaaa gtaaccattc aaaagtttga
    13381 cccttatatc aatattgatc cgggaaccat gagtccttac cagcacgggg aagtttttgt
    13441 gacagatgac ggagctgaga cagatttgga cttgggtcac tatgaacgtt tcatcgatat
    13501 caatctcaac aaatattcca acgtgacaac tgggaaaatt tacagtgaag ttcttcgtaa
    13561 agaacgccgt ggagaatacc ttggggcaac tgttcaagtc attcctcata tcacagatgc
    13621 tttgaaagaa aaaatcaagc gtgccgctct aacgaccgac tctgatgtca ttatcacaga
    13681 ggttggtgga acagtaggag atatcgagtc cttgccattc ctagaggctc ttcgtcagat
    13741 gaaggcagat gtgggtgcgg ataatgtcat gtatatccat acaaccttgc ttccttacct
    13801 caaggctgct ggtgaaatga aaaccaaacc aacccaacac tctgtcaaag aattgcgtgg
    13861 cttgggaatc caaccaaata tgttggttat tcgtacagaa gagccagctg gtcaaggaat
    13921 taaaaataaa ctggcccagt tctgtgatgt ggcaccagaa gccgttatcg aatcgttgga
    13981 tgttgaacac ctttaccaaa ttccactgaa cttgcaggca caagggatgg accaaattgt
    14041 ttgtgatcat ttgaaattag acgcaccagc agcggatatg acagaatggt cagccatggt
    14101 ggacaaggtc atgaacctca agaaacaagt taagatttcc cttgttggta agtatgtgga
    14161 gttgcaagat gcctatatct cagtggtcga agccttgaaa cactctggct atgtcaatga
    14221 tgtagaagtt aaaatcaatt gggtcaatgc caatgatgtg acagcagaga atgtagcaga
    14281 actcttgtct gatgcggacg ggatcatcgt accaggtggt tttggtcaac gtggtacaga
    14341 agggaaaatc caagccatcc gctatgcgcg tgaaaatgat gttccaatgt tgggagtctg
    14401 cttgggaatg cagttgacat gtatcgagtt tgctcgtcac gttttaggtc ttgaaggtgc
    14461 caattctgca gagcttgcac cagaaacaaa ataccctatc attgatatca tgcgtgatca
    14521 gattgatatt gaggatatgg gtggaaccct tcgtttggga ctttatccgt ctaagttgaa
    14581 acgtggctct aaggctgctg ctgcttatca caatcaagaa gtggtgcaac gccgtcaccg
    14641 tcaccgttat gagtttaata atgccttccg tgagcagttt gaggcagcag gttttgtctt
    14701 ttcaggagtt tctccagaca atcgtttggt agaaatcgtg gaaattcctg aaaataaatt
    14761 ctttgtagct tgtcagtatc accctgaact gtcaagccgt ccaaaccgac cagaagaact
    14821 ctacactgcc tttgttactg cagcggttga gaacagcaat tagcaaaatc agaacctttg
    14881 agaaaaatct cagaggtttt ttgcatacga tgatattgca atatatctga ggtagggggc
    14941 ctctgtatgt acctgctacc gttgaaatca atagcgactc cctcttgccc tgtgctagtg
    15001 aatggattta tcagtatatt gaaatgaaat aaaatttgaa caaattaatt cggaaagcca
    15061 aatcaatttc tagcaaagtt ttaggaactg gattgtatag tgaattgaaa taagatgtga
    15121 acatctctat cagaaaagtc aaattaattt atagaaatat tttagcagtc aagatgtact
    15181 gttatagatt caatacatta tactttttta atttaatcca ctatagtaaa atgaaataag
    15241 aacaggacaa atcgatcagg acagtcaaat cgatttctaa caatgtttta gaaatagagg
    15301 tgtactattc tagtttcaat atactatata tctgcagaat actctttcag tttcattcag
    15361 cctagtcttg cttaggaaaa agtaaaaagc catccaatta tgatggatag cttcttggtt
    15421 cttagatttg ttctgcaaaa accttttcag caaggttcat agcgtggtct gatacacgag
    15481 tgtagtgtga gatgatgtcg ataaagttga ccccagcttg tgttgaacat tcgcctttgt
    15541 tgaggcgttt gatgtgggtt tttctgagaa cacgttctat cttattgatt gcttcatgac
    15601 gttctacaag actgcgtgct ttttcaatat cattgttttc cacactatcc agagcatctt
    15661 tgataaagtc actagtttgg cggtaaactt cctctaattc tttcaaggcg gcatcagaaa
    15721 attcaacatt tttccgttga agatagtcag tcagattgag tagagcctcc gtgtggtctc
    15781 caatccgttc caaatcacgg gaggaatcaa ggatattggt aagcacttca ctttcttttt
    15841 ggctgagagc ttcgcttgaa agggcaatga gataacgtgt taattgctca tcgatggtgt
    15901 taattgcttc ttcggtttta tgcccttttt cagcaacttt ttcatccaag tcaatgatgt
    15961 acttatagga aaggtcaaag gctttagcag cgtagtttcc taagtgcaag agctctttct
    16021 tagcatttcc tagagcgata gatggggcct gtttgatgaa atgttcatca agatataagg
    16081 gttcgtattt gacaacctcg tcctctccag gaataatctt ggttacaaag taagccagag
    16141 ctccgataaa tggaaattgg acaatggtgt tggtaatatt aaaggttccg tgagcaaagg
    16201 cgatggtcat ttccggtgct agatttagcg tagcttcaaa ccaatgaatc aggacagtaa
    16261 aaggaactag aaaaataacg cagacgactg ttccgataac gttgaaggca acatgagctc
    16321 ctgctacccg tttagctgca atattagccc ctaaagaggc aatgatggct gtaatggtta
    16381 tcccgatatt gtcaccaaat agaactggca aagctccctg taggtcaatt agattgccgg
    16441 cgtagaggtt ttgtaaaatc ccaatggtag ccgaagaagc ttgaattagc aaggtcaagc
    16501 cggtaccgac aaagacaccc aaaacaggat tcttacttag ctcaatcata tagtccttaa
    16561 agacctgtaa atccttgagt ggagccattg cgccgctcat gagattgagg gcaaaaaaga
    16621 taccaccgac accaaagagg atgcgtccga tattattgac tgtccgattt tttgtaaaaa
    16681 agagacagac ggcaccgata aagagcatag gtagggcata gttacctaat ttaaaaccga
    16741 tgagaaagga tgtgacagtt gtcccaatat tagcacccat gacaatcccg atagcctgac
    16801 gtaaggttaa gagaccggca ctgaccaggc cgactgtgat aactgttaca ccagaactag
    16861 actgaattag agcagtcatc ccaataccaa ccagaactcc aaagaaagga ttactagtat
    16921 atttgtcaat gtaaaaacga aggcgatctc cagcagcttg ttgcaaaccg tctcccatgg
    16981 tcttgatgct atataagaat agccccagac cacctaaaaa gtgaaataaa atttcctgcc
    17041 aattaatgga catttctttt tcctccgaaa aataatcgcg gaatatcttc tattctattt
    17101 taaaggataa aagtaaatct aacaagtgtt aatgtcaagt ttgtaaaaga aaattataat
    17161 tgataagtgt attattttta agagttttta accttatttt agatttgtgc aaacagttat
    17221 tgttttttgt ctaaaaatgt tttaggataa aaatgtgatt atcatggttc tagagtttga
    17281 taaaaaacta cagaatataa agcgctttct tgaaaacaac aaaatcaatc ttttaggagg
    17341 agaaaatgaa gaatccattt tttgaaagac gttgtcgtta cagtattcgt aagttatcag
    17401 taggagcctg ctcgctgatg attggtgctg ttttatttgc tggtccagcc ttggctgaag
    17461 aaactgcagt tcctgaaaat agcggagcta atacagagct tgtttcagga gagagtgagc
    17521 attcgaccaa tgaagctgat aagcagaatg aaggggaaca tgctagagaa aacaagctag
    17581 aaaaggcaga aggagtagcg atagcatctg aaactgcttc gccagcaagc aatgaagctg
    17641 caactactga aactgcagaa gcagctagcg cagctaaacc agaggaaaaa gcaagtgagg
    17701 tggttgcaga aacaccatct gcagaagcaa aacctaagtc tgacaaggaa acagaagcaa
    17761 agcccgaagc aactaaccaa ggggatgagt ctaaaccagc agcagaagct aataagactg
    17821 aaaaagaagt ccagccagat gtccctaaaa atacagaaaa aacattaaaa ccaaaggaaa
    17881 tcaaatttaa ttcatgggaa gaattgttaa aatgggaacc aggtgctcgt gaagatgatg
    17941 ctattaaccg cggatctgtt gtcctcgctt cacgtcggac aggtcattta gtcaatgaaa
    18001 aagctagcaa ggaagcaaaa gttcaagcct tatcaaacac caattctaaa gcaaaagacc
    18061 atgcttctgt tggtggagaa gagttcaagg cctatgcttt tgactattgg caatatctag
    18121 attcaatggt cttctgggaa ggtctcgtac caactcctga cgttattgat gcaggtcacc
    18181 gtaacggggt tcctgtatac ggtacactct tcttcaactg gtctaatagt attgcagatc
    18241 aagaaagatt tgctgaagct ttgaagcaag acgcagatgg tagcttccca attgcccgta
    18301 aattggtaga catggccaag tattatggct atgatggcta tttcatcaac caagaaacaa
    18361 ctggagattt ggttaaacct cttggagaaa agatgcgcca gtttatgctc tatagcaagg
    18421 aatatgctgc taaggtaaac catccaatca agtattcttg gtacgatgcc atgacctata
    18481 actatggacg ttaccatcaa gatggtttgg gagaatacaa ctaccaattc atgcaaccag
    18541 aaggagataa ggttccggca gataacttct ttgctaactt taactgggat aaggctaaaa
    18601 atgattacac tattgcaact gccaactgga ttggtcgtaa tccttatgat gtatttgcag
    18661 gtttggaatt gcaacagggt ggttcctaca agacaaaggt taagtggaat gacattttag
    18721 acgaaaatgg gaaattgcgc ctttctcttg gtttatttgc cccagatacc attacaagtt
    18781 taggaaaaac tggtgaagat tatcataaaa atgaagatat cttctttaca ggttatcaag
    18841 gagaccctac tggccaaaaa ccaggtgaca aagattggta tggtattgct aacctagttg
    18901 cggaccgtac gccagcggta ggtaatactt ttactacttc ttttaataca ggtcatggta
    18961 aaaaatggtt cgtagatggt aaggtttcta aggattctga gtggaattat cgttcagtat
    19021 caggtgttct tccaacatgg cgctggtggc agacttcaac aggggaaaaa cttcgtgcag
    19081 aatatgattt tacagatgcc tataatggcg gaaattccct taaattctct ggtgatgtag
    19141 ccggtaagac agatcaggat gtgagacttt attctactaa gttagaagta actgagaaga
    19201 ccaaacttcg tgttgcccac aagggaggaa aaggttctaa agtttatatg gcattctcta
    19261 caactccaga ctacaaattc gatgatgcag atgcatggaa agagctaacc ctttctgaca
    19321 actggacaaa tgaagaattt gatctcagct cactagcagg taaaaccatc tatgcagtca
    19381 aactattttt cgagcatgaa ggtgctgtaa aagattatca gttcaacctc ggacaattaa
    19441 ctatctcgga caatcaccaa gagccacaat cgccgacaag cttttctgta gtgaaacaat
    19501 ctcttaaaaa tgcccaagaa gcggaagcag ttgtgcaatt taaaggcaac aaggatgcag
    19561 atttctatga agtttatgaa aaagatggag acagctggaa attactaact ggctcatctt
    19621 ctacaactat ttatctacca aaagttagcc gctcagcaag tgctcagggt acaactcaag
    19681 aactgaaggt tgtagcagtc ggtaaaaatg gagttcgttc agaagctgca accacaacct
    19741 ttgattgggg tatgactgta aaagatacca gcctaccaaa accactagct gaaaatatcg
    19801 ttccaggtgc aacagttatt gatagtactt tccctaagac tgaaggtgga gaaggtattg
    19861 aaggtatgtt gaacggtacc attactagct tgtcagataa atggtcttca gctcagttga
    19921 gtggtagtgt ggatattcgt ttgaccaagc cacgtaccgt tgttagatgg gtcatggatc
    19981 atgcaggagc tggtggtgag tctgttaacg atggcttgat gaacactaaa gactttgacc
    20041 tttattataa agatgcagat ggtgagtgga agctagctaa ggaagtccgt ggtaacaaag
    20101 cacacgtgac agatatcact cttgataaac caatcactgc tcaagactgg cgcttgaatg
    20161 ttgtcacttc tgacaatgga actccatgga aggctattcg tatctataac tggaaaatgt
    20221 atgaaaagct tgatactgag agtgtcaata ttccgatggc caaggctgca gcccgttctc
    20281 taggcaataa caaggtacaa gttggctttg cagatgtacc ggctggagca actattaccg
    20341 tttatgataa tccaaattct caaactccgc tcgcaacctt gaagagcgaa gttggaggag
    20401 acctagcaag tgcaccattg gatttgacaa atcaatctgg tcttctttat tatcgtaccc
    20461 agttgccagg caaggaaatt agtaatgtcc tagcagtttc cgttccaaaa gatgacagaa
    20521 gaatcaagtc agtcagccta gaaacaggac ctaagaaaac aagctacgcc gaaggggagg
    20581 atttggacct tagaggtggt gttcttcgag ttcagtatga aggaggaact gaggacgaac
    20641 tcattcgcct aactcacgca ggtgtatcag tatcaggttt tgatacgcat cataagggag
    20701 aacagaatct tactctccaa tatttgggac aaccagtaaa tgctaatttg tcagtgactg
    20761 tcactggcca agatgaagca agtccgaaaa ctattttggg aattgaagta agtcaggaac
    20821 cgaaaaaaga ttacctagtt ggtgatagct tagacttgtc tgaaggacgc tttgcagtgg
    20881 cttatagcaa tgacaccatg gaagaacatt cctttactga tgagggagtt gaaatttctg
    20941 gttacgatgc tcaaaagact ggtcgtcaaa ccttgacgct tcgttaccaa ggtcatgaag
    21001 tcaactttga tgttttggta tctccaaaag cagcattgaa cgatgagtac ctcaaacaaa
    21061 aattagcaga ggttgaagct gctaagaaca aggtggtcta taactttgct tcaccagaag
    21121 taaaagaagc tttcttgaaa gcaattgaag cggccgaaca agtgttgaaa gaccatgaaa
    21181 ctagcaccca agatcaagtc aatgaccgac ttaataaatt gacagaagct cataaagctc
    21241 tgaatggtca agagaaattt aaggaagaaa agacagagct tgatcgttta acaggtgagg
    21301 ttcaagaact cttggctgcc aaaccaaacc atccttcagg ttctgcccta gctccgcttc
    21361 ttgagaaaaa caaggccttg gttgaaaaag tagatttgag tccagaagag cttgcaacag
    21421 cgaaacagag tctaaaagat ctggttgctt tattgaaaga agacaagcca gcagtctttt
    21481 ctgatagtaa aacaggtgtt gaagtacact tctcaaataa agagaagact gtcatcaagg
    21541 gtttgaaagt agagcgtgtt caagcaagtg ctgaagagaa gaaatacttt gctggagaag
    21601 atgctcatgt ctttgaaata gaaggtttgg atgaaaaagg tcaagatgtt gatctctctt
    21661 acgcttctat tgtgaaaatc ccaattgaaa aagataagaa agttaagaaa gtatttttct
    21721 tacctgaagg caaagaggca gtagaattgg cttttgaaca aacggatagt catgttatct
    21781 ttacagcacc acactttact cattatgcct ttgtttatga atctgctgaa aaaccacaac
    21841 ctgctaaacc agcaccacaa aacaaagtcc ttccaaaacc tacttatcaa ccggcttctg
    21901 atcaacaaaa ggctcctaaa ttggaagttc aagaggaaaa ggttgccttt catcgtcaag
    21961 agcatgaaaa tgctgagatg ctagttgggg aacaacgagt catcatacag ggacgagatg
    22021 gactgttaag acatgtcttt gaagttgatg aaaacggtca gcgtcgtctt cgttcaacag
    22081 aagtcatcca agaagcgatt ccagaaattg ttgaaattgg aacaaaagta aaaacagtac
    22141 cagcagtagt agctacacag gaaaaaccag ctcaaaatac agcagttaaa tcagaagaag
    22201 caagcaaaca attgccaaat acaggaacag ctgatgctaa tgaagcccta atagcagtct
    22261 tagccagcct tggtcttgct agtttagcct tgaccttgag acggaaaaga gaagataaag
    22321 attaaatatc gaaaaatctt gtgaaatctt tccttatatt tccaaagtgt gatataatag
    22381 tttcgaataa aataaataaa ggagtttttg taacatggca aaacttactg ttaaagacgt
    22441 tgacttgaaa ggtaaaaaag tcctcgttcg tgttgacttc aacgtaccat tgaaagatgg
    22501 cgtaatcact aacgataacc gtatcacagc agctcttcca actattaagt acatcatcga
    22561 acaaggtgga cgtgcaattc ttttctctca ccttggacgt gtgaaagaag aagctgataa
    22621 agctggcaaa tcacttgctc ctgtagcagc tgacttggca gcaaaacttg gtcaagatgt
    22681 tgttttccca ggtgtcactc gtggtgctga attggaagcg gcaatcaacg ctcttgaaga
    22741 tggacaagtt ctcttggttg aaaacactcg ttacgaagat gttgacggca agaaagaatc
    22801 taaaaacgat cctgaacttg gtaaatactg ggcatcactt ggagatggta tcttcgtaaa
    22861 cgatgcattc ggtacagctc accgtgcaca cgcatctaac gttggtatct cagcaaacgt
    22921 tgaaaaagca gttgctggtt tccttcttga aaacgaaatt gcctacatcc aagaagcagt
    22981 tgaaactcca gaacgtccat tcgtggctat ccttggtggt tcaaaagttt cagacaagat
    23041 cggtgttatc gaaaacttgc ttgaaaaagc tgataaagtc cttatcggtg gtgggatgac
    23101 ttacacattc tacaaagcac aaggtatcga aatcggtaac tcacttgtag aagaagacaa
    23161 attggatgtt gcgaaagctc ttcttgaaaa agcaaatggt aaattgatct tgccagttga
    23221 ctcaaaagaa gctaacgcat ttgctggtta cactgaagtg cgtgacactg aaggtgaagc
    23281 agtttctgaa ggcttccttg gtcttgacat cggtccaaaa tctatcgcca aatttgacga
    23341 agctttgact ggtgccaaaa cagttgtatg gaacggacct atgggtgtat ttgaaaaccc
    23401 agatttccaa gctggtacaa tcggtgtgat ggacgctatc gtgaaacaac caggagttaa
    23461 atcaatcatc ggtggtggtg actcagctgc cgcagcgatt aaccttggcc gtgcagacaa
    23521 gttctcatgg attagtacgg gtggtggagc atcaatggaa cttcttgaag gtaaggttct
    23581 tccaggactt gcagccttga cagaaaaata agattttata aacaaatcaa agaagagagg
    23641 gatgaaagtt cctcttttct tttgcttaaa ataaaaacgc ttcctctcaa ctattactca
    23701 taaaaatcac cgatttatga taaaatggaa atagaaagtt gagattatga gttattttaa
    23761 aaaatataaa ttcgataaat cccagttcaa acttggtatg cgaaccttta aaacaggtat
    23821 tgctgttttt ctagttctct tgatttttgg cttttttggc tggaaaggtc ttcaaattgg
    23881 tgctttgaca gccgttttta gcctgaggga gagttttgat gagagtgttc attttgggac
    23941 ttcgcgtatt ctaggaaata gtatcggtgg actctatgcc ttggtcttct tcttattaaa
    24001 tacttttttc cacgaagcct tttgggtgac cttggtagtt gttccaatct gcaccatgtt
    24061 aaccattatg acaaatgtag ccatgaataa caaagcaggg gttattggtg gtgtagcagc
    24121 tatgttaatc attaccctat caattccaag tggtgagaca attttgtacg tgtttgtgcg
    24181 tgtattagaa acgtttatgg gagtttttgt cgcaattatc gtaaattacg atattgatcg
    24241 tattcgtctc tttttagaga aaaaagaaaa ataatgttac attttataac attatcaatt
    24301 gacgtttgtc tttttttaga ctataataga cagaaagaag gaaattgtaa atgaaggaaa
    24361 aagaatttcg ccgaaatatg gctgtttttc ctatcggcag tgttatgaag ttgaccgatt
    24421 tatcggcgcg tcagattcgt tattatgaag atcaagagtt gatcaagccc gatcgaaacg
    24481 aaggaaatcg tcgcatgtat tccttgaatg acatggatcg tctgcttgaa atcaaagatt
    24541 atatctctga aggttataat atcgctgcca ttaagaaaaa atatgctgaa cgtgaagcga
    24601 aatccaagaa agcggttagt cagactgaag tacgtcgtgc acttcacaat gaactcctcc
    24661 aacaggggcg ttttgcttca gtacagtcac cttttggtcg cggttaggca accgcaagta
    24721 gtcatagatt aaggagaaaa cttatgccaa tcacagctgc agatattcgt cgtgaagtca
    24781 aggaaaaaaa tgttaccttt attcgtctta tgttctcaga tattttggga accatgaaaa
    24841 acgtcgaaat tcctgctaca gatgaacagt tagataaggt cttgtcgaac aaggttatgt
    24901 ttgatggatc ttctattgaa ggttttgtac gtatcaatga gtcggatatg tacttgtacc
    24961 cggacttgga tacatggaca gtcttccctt ggggagatga aaatggaagt gttgcaggtc
    25021 tgatctgtga tgtctataca acagaaggtg aaccatttgc gggtgaccct cgtggtaatt
    25081 tgaaacgagc tcttcgtcac atggaagaag ttggattcaa atccttcaac cttggtccag
    25141 agccagaatt cttcctattt aagttggatg aaaatgggga cccaacactt gaagtgaatg
    25201 acaagggtgg ctactttgat ttggcaccta ctgaccttgc ggacaacaca cgtcgtgaga
    25261 ttgtgaatgt cttgaccaaa atgggatttg aagtagaagc gagtcaccac gaggttgcgg
    25321 ttggacagca tgagattgac tttaagtacg atgaagttct ccgtgcttgt gataagattc
    25381 aaatctttaa gcttgttgtt aaaaccattg ctcgcaaaca cggactttac gcaacattta
    25441 tggcgaagcc aaaatttggt attgctggat caggtatgca ctgtaatatg tccttgtttg
    25501 atgcagaagg aaataacgcc ttctttgatc caaatgatcc aaaaggaatg cagttgtcag
    25561 aaacagctta ccatttccta ggcggtttga tcaagcatgc ttacaactat actgccatca
    25621 tgaacccaac agttaactca tacaaacgtt tggttccagg ttatgaagcg cctgtttaca
    25681 ttgcttgggc tggtcgtaac cgttcgccac ttgtgcgcgt acctgcttca cgtggtatgg
    25741 gaactcgtct tgagttgcgt tcagtggatc caatggcgaa cccttacatt gctatggctg
    25801 ttcttttgga agttggtttg tatggtattg aaaataaaat cgaagcacca gctcctatcg
    25861 aagaaaatat ctacatcatg acagcagaag agcgcaagga agctggtatt acagaccttc
    25921 catcaactct tcacaacgct ttgaaagctt tgacagaaga tgaagtggtt aaagctgctc
    25981 tcggagatca catctacact agcttccttg aagccaaacg aatcgaatgg gcaagttatg
    26041 caaccttcgt ttcacaatgg gaaattgata attatttaga cctttactaa tactaatata
    26101 gaagaaagat tgcctgtggg taaacagtca cacagcagtc taagccatca aatacctata
    26161 acccttaaaa tagcgatttc ggtcgctatt tatttttcga aaaatcctct tgactctttt
    26221 gcgaattaga tttatcatca gacgtgtaga agaaaatcaa ggagtcacta tggaaaaatt
    26281 caatttcaaa aacaatatcg ggcaagaaaa caagttactt caaatcgaaa tctacaagtt
    26341 tactaacttt tgcaagcttc aaaattacac atctgtaaat attttttcga aagatatatt
    26401 tgaagccata gtaaattgag actagaatag tacactacat ctgctaaaaa tttctagaaa
    26461 ttaatttaac tttcctaatc gatttgttta catcttattt caatctacta tattatctca
    26521 ataaatgatg atggcgactg ttttgtttgt gcttgtcgat ttttgaatcc tgatcgagcg
    26581 gaagaatatt tctgccgagg ttgtcaaggg gaaaatcctg aagatattga attttatgat
    26641 gaacaattac aggcagaaaa ggtggaggct ttgaatattc gattggaagt aaaaaattga
    26701 attatctaca atctcatcaa caataaacct atttcaaccc cattatctat aggcgtattt
    26761 ttacgccttt ttatatactt gaagcacata agaaacatta tgggaagttt gctgatggaa
    26821 gtactcaaga aattgatgtt ccttatgata ttcctgatac ttgggagtgg gtgaggataa
    26881 aatcaattta ttggaatttt gggcaaaata agccagagaa atcctttagg tatatagata
    26941 cgtctagtat tgatagaaaa aagaacataa tcaactacaa aaatctacaa tatctttcac
    27001 ctgaacaagc gccttcccgt gccagaaaat tagtttcgca gaatagtgtc ttattttcaa
    27061 cagttagacc atatctaaaa aatattgctg tagttagaga acttaaagag tatttgatag
    27121 ctagtacagc atttattgtt ttggatactt tacttaacga aacatatttg aaatattatt
    27181 tattatcaga taattttatc aatcgtgtta ataataaatc tactggaaca agttatcctg
    27241 caatcaatga ttataatttt aatctattat taatt
//
LOCUS       DAVBBO010000027        26062 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ST1
            SAMEA2066453-rid20184263.denovo.027, whole genome shotgun sequence.
ACCESSION   DAVBBO010000027 DAVBBO010000000
VERSION     DAVBBO010000027.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2066453
            Sequence Read Archive: ERR351777
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 26062)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 26062)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980402.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980402.1
            Genome Coverage       :: 176x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:17:33
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,141
            CDSs (total)                      :: 2,104
            Genes (coding)                    :: 1,953
            CDSs (with protein)               :: 1,953
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 16S)
            partial rRNAs                     :: 1 (23S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 151
            CDSs (without protein)            :: 151
            Pseudo Genes (ambiguous residues) :: 0 of 151
            Pseudo Genes (frameshifted)       :: 73 of 151
            Pseudo Genes (incomplete)         :: 76 of 151
            Pseudo Genes (internal stop)      :: 40 of 151
            Pseudo Genes (multiple problems)  :: 32 of 151
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..26062
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2066453-rid20184263.denovo.027"
                     /strain="ST1"
                     /db_xref="taxon:1313"
     gene            <1..169
                     /locus_tag="VQU30_001129"
     CDS             <1..169
                     /locus_tag="VQU30_001129"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HET2447245.1"
                     /translation="KAYNHALSKERSKVENIFAKVKTFKIFSTTYRNHRKRFGLRMNL
                     SAGIINHELGF"
     gene            complement(332..583)
                     /locus_tag="VQU30_001130"
     CDS             complement(332..583)
                     /locus_tag="VQU30_001130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000604885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2447246.1"
                     /translation="MPKTKTLAELADVILWSFDFANDHAHAFFMDNVEWSHADSYFLS
                     FVSDDVEERYIENVYLDSLSVKQKFKFIFDFGDEWRFEC"
     gene            complement(873..2753)
                     /locus_tag="VQU30_001131"
     CDS             complement(873..2753)
                     /locus_tag="VQU30_001131"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-N-acetylhexosaminidase"
                     /protein_id="HET2447247.1"
                     /translation="MVRFTGLSPKQTQAIEVLKGHISLPDVEVAVTQSDQASISIQGE
                     EGHYQLTYRKPHQLYRALSLLVTVLAEADKVEIEEQAAYEDLAYMVDCSRNAVLNVAS
                     AKQMIEVLALMGYSTFELYMEDTYQIEGQPYFGYFRGAYSAEELQEIEAYAQQFDMTF
                     VPCIQTLAHLSAFVKWGVKEVQELRDVEDILLIGEEKVYDLIDGMFATLSKLKTRKVN
                     IGMDEAHLVGLGRYLILNGVVDRSLLMCQHLERVLDIADKYGFHCQMWSDMFFKLMSA
                     DGQYDRDVEIPEETRVYLDRLKDRVTLVYWDYYQDSEEKYNRNFRNHHKISHDLAFAG
                     GAWKWIGFTPHNHFSRLVAIEANKACRANQIKEVIVTGWGDNGGETAQFSILPSLQIW
                     AELSYRNDLDGLSAHFKTNTGLTVEDFMQIDLANLLPDLPGNLSGINPNRYVFYQDIL
                     CPILDQHMTPEQDKPHFAQAAETLANIKEKAGNYAYLFETQAQLNAILSSKVDVGRRI
                     RQAYQADDKESLQQIARQELPELRSQIEDFHALFSHQWLKENKVFGLDTVDIRMGGLL
                     QRIKRAESRIEVYLAGQLDRIDELEVEILPFTDFYADKDFAATTANQWHTIATASTIY
                     TT"
     gene            complement(2747..3616)
                     /locus_tag="VQU30_001132"
     CDS             complement(2747..3616)
                     /locus_tag="VQU30_001132"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HET2447248.1"
                     /translation="MTIATIDIGGTGIKFASLTPDGKILDKTSISTPENLEDLLAWLD
                     QRLSEQDYSGIAMSVPGAVNQETGVIDGFSAVPYIHGFSWYEALSSYQLPVHLENDAN
                     CVGLSELLAHPDLENAACVVIGTGIGGAMIINGRLHRGRHGLGGEFGYMTTLAPAEKL
                     NNWSQLASTGNMVRYVIEKSGHTDWDGRKIYQEAAAGNILCQEAIERMNRNLAQGLLN
                     IQYLIDPDVISLGGSISQNPDFIQDVKKAVDNFVDTYEEYTVAPVIQACTYHADANLY
                     GALVNWLQEEKQW"
     gene            complement(3700..6345)
                     /locus_tag="VQU30_001133"
     CDS             complement(3700..6345)
                     /locus_tag="VQU30_001133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000432759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-mannosidase"
                     /protein_id="HET2447249.1"
                     /translation="MENVVVHIISHSHWDREWYLPFESHRMQLVELFDNLFDLFENDP
                     EFKSFHLDGQTIVLDDYLQIRPENRDKVQRYIDEGKLKIGPFYILQDDYLISSEANVR
                     NTLIGQQEAAKWGKSTQIGYFPDTFGNMGQAPQILQKSGIHVAAFGRGVKPIGFDNQV
                     LEDERFTSQFSEMYWQGVDGSRVLGILFANWYSNGNEIPVDKDEALTFWKQKLSDVRA
                     YASTNQWLMMNGCDHQPVQKNLSEAIRVANELFPDVIFVHSSFDEYVQAVEGALPEHL
                     STVTGELTSQETDGWYTLANTSSSRIYLKQAFQENSNLLEQVVEPLTIITGGHNHKDQ
                     LTYAWKTLLQNAPHDSICGCSVDEVHREMETRFAKVNQVGNFVKSNLLNEWKGKIATD
                     KAQSDYLFTVINTGLHDKVDTVSTVIDVATCDFKELHPTEGYKKMAALILPSYRVEDL
                     DGRPVEATIEDLGANFEYDLPKDKFRQARIARQVRVTIPVHLAPLSWTTFQLLEGKQE
                     HREGIYQNGVIDTPFVTVSVDDNITVYDKTTHEAYEDFIRFEDRGDIGNEYIYFQPKG
                     TEPIFAELKGHEVLENTDRYAKILLKHELTVPVSADEKLEEEQQGIIEFMKREAGRSE
                     ELTNIPLETELIVFVDNPQIRFKTRFTNTAKDHRIRLLVKTHNTRPSNDSESIYEVVT
                     RPNKPAASWENPENPQHQQAFVSLYDDEKGVTVSNKGLNEYEILGDNTIAVTILRASG
                     ELGDWGYFPTPEAQCLREFEVEFALECHQAQERFSAFRRAKALQTPFTSLQLARQEGS
                     VVATGSLLSHSVLSIPQVCPTAFKVAENEEGYVFRYYNMSQENVHISEHQQTILDLLE
                     RPYPVHSGPLDPQEIRTEFIKKEEI"
     gene            complement(6436..7716)
                     /locus_tag="VQU30_001134"
     CDS             complement(6436..7716)
                     /locus_tag="VQU30_001134"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844830.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 125 protein"
                     /protein_id="HET2447250.1"
                     /translation="MIYSKEIVREWLDEVAERAKDHPEWVDVFERCYTDTLDNTVEIL
                     EDGSTFVLTGDIPAMWLRDSTAQLRPYLHVAKRDALLRQTIAGLVKRQMTLVLKDPYA
                     NSFNIEENWKGHHETDHTDLNGWIWERKYEVDSLCYPLQLAYLLWKETGETSQFDETF
                     VAATKEILHLWTVEQDHKNSPYRFVRDTDRKEDTLVNDGFGPDFAVTGMTWSAFRPSD
                     DCCQYSYLIPSNMFAVVVLGYVQEIFAALNLADSQSVIADAKRLQDEIQEGIENYAYT
                     TNSKGEKIYAFEVDGLGNASIMDDPNVPSLLAAPYLGYCSIDDEVYQATRRTILSSEN
                     PYFYQGEYASGLGSSHTFYRYIWPIALSIQGLTTRDKAEKKFLLDQLVACDGGTGVMH
                     ESFHVDDPTLYSREWFSWANMMFCELVLDYLDIR"
     gene            7887..9971
                     /locus_tag="VQU30_001135"
     CDS             7887..9971
                     /locus_tag="VQU30_001135"
                     /EC_number="3.2.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000803403.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GH92 family glycosyl hydrolase"
                     /protein_id="HET2447251.1"
                     /translation="MKPLLETIDTRFGTASKHAFSRGNTLPYTGVPFGMNYFVPQTSD
                     QDGSWFFDPHLPIFQGIRLTHQPSPWIGDYSWLLLTPVTSQLGGDSLFHRQSSYDIDK
                     ACFQPHYLKLFSLRYQIETQLTPTCYGASIRLNQKQGKALSLYLHAADELTVEQVDKR
                     TLALRQEGKTETNKNSLTMFTALQMNTDILAISQEAGDWRIDLASSQTEMQLATSFIS
                     PSQALINLPQEDFDSCKTSAQADWENLLHRFDIIETGEADRTFFDHCLYRLFLFPQTF
                     YEVDESGKAIHMDLATGTVKPGVLFSNNGFWDTFRTTFPLFALIIPEHYQRFLEGFLN
                     SYRDTGFLPKWLAPDERGMMPGTLLDGIIADSACKDMAPDLEGELFQAMLETASKADP
                     LGINGRHGLAQYQELGYLSTDHHESVSHTLDYAYSDFCIASCAKKLENIEIAETYKAA
                     SQNYRQLFDAETGYMRARDNQGNFHPDFSPYSWGRDYAECSAIQATLGVLHDIPGLIQ
                     LMGGKETFSNYLLKACQDAPLFETTGYGYEIHEMSEMATAPFGQIAISNQPSFHIPYL
                     FRYSDYPDYTALLIKTLRQKAFHPSWEAYPGDEDNGSLSAWYIWSALGFYPTCPGKPS
                     YDLGIPLFDHLRVYLAKENKWLDIHTEQNHSHFNFVKECRLDKTLVSTIQHQDLLKAE
                     QLTFTLSWLPNH"
     gene            complement(10011..11690)
                     /locus_tag="VQU30_001136"
     CDS             complement(10011..11690)
                     /locus_tag="VQU30_001136"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000721501.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-L-fucosidase"
                     /protein_id="HET2447252.1"
                     /translation="MKKIKPHGPLPSQTQLAYLGDELAAFIHFGPNTFYDQEWGTGQE
                     DPERFNPSQLDAREWVRVLKETGFKKLILVVKHHDGFVLYPTAHTDYSVKVSPWRRGK
                     GDLLLEVSQAATEFDMDMGVYLSPWDAHSPLYHVDREADYNAYYLAQLKEILSNPNYG
                     NAGKFAEVWMDGARGEGAQKVNYEFEKWFETIRDLQGDCLIFSTEGTSIRWIGNERGY
                     AGDPLWQKVNLDKLGTEAELNYLQHGDPSGTIFSIGEADVSIRPGWFYHEDQDPKSLE
                     ELVEIYFHSVGRGTPLLLNIPPNQAGLFDAKDIERLYEFATYRNELYKEDLALGAEVS
                     GPALSADFDCRHLTDGLETSSWASDADLPIQLELDLGSPKTFDVIELREDLKLGQRIA
                     AFHVQVEVDGVWQEFGRGFTVGHKRLLRGPLVEAQKVRVMITEAQSIPVLTKISLYKT
                     PGLSKKEVVQELAFAEKSLAVAKGETLHFRIERSESSSSLEAKISIQPGTGVHGVAYQ
                     DEIYVLAFQAGETEKRLTLPTLYFAGDKTLDFYLNLTVDGQLVDQLQVQVS"
     gene            12445..13674
                     /gene="arcA"
                     /locus_tag="VQU30_001137"
     CDS             12445..13674
                     /gene="arcA"
                     /locus_tag="VQU30_001137"
                     /EC_number="3.5.3.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000094613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine deiminase"
                     /protein_id="HET2447253.1"
                     /translation="MSSHPIQVFSEIGKLKKVMLHRPGKELENLLPDYLERLLFDDIP
                     FLEDAQKEHDAFAQALRDEGIEVLYLEQLAAESLTSPEIRDQFIEEYLDEANIRDRQT
                     KVAIRELLHGIKDNQELVEKTMAGIQKVELPEIPDEAKDLTDLVESDYPFAIDPMPNL
                     YFTRDPFATIGNAVSLNHMFADTRNRETLYGKYIFKYHPIYGGKVDLVYNREEDTRIE
                     GGDELILSKDVLAVGISQRTDAASIEKLLVNIFKKNVGFKKVLAFEFANNRKFMHLDT
                     VFTMVDYDKFTIHPEIEGNLHVYSVTYENEKLKIVEEKGDLAELLAQNLGVEKVHLIR
                     CGGGNIVAAAREQWNDGSNTLTIAPGVVVVYDRNTVTNKILEEYGLRLIKIRGSELVR
                     GRGGPRCMSMPFEREEV"
     gene            13732..14748
                     /gene="argF"
                     /locus_tag="VQU30_001138"
     CDS             13732..14748
                     /gene="argF"
                     /locus_tag="VQU30_001138"
                     /EC_number="2.1.3.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003073325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ornithine carbamoyltransferase"
                     /protein_id="HET2447254.1"
                     /translation="MTNSVFQGRSFLAEKDFTRAELEYLIGLSAHLKDLKKRNIQHHY
                     LAGKNIALLFEKTSTRTRAAFTTAAIDLGAHPEYLGANDIQLGKKESTEDTAKVLGRM
                     FDGIEFRGFSQRMVEELAEFSGVPVWNGLTDEWHPTQMLADYLTVQENFGRLEGLTLV
                     YCGDGRNNVANSLLVTGAILGVNVHIFSPKELFPEKEIVELAEGFAKESGAHVLITED
                     ADEAVKDADVLYTDVWVSMGEEDKFAERVALLKPYQVNMDLVKKAGNENLIFLHCLPA
                     FHDTHTVYGKDVAEKFGVEEMEVTDEVFRSKYARHFDQAENRMHTIKAVMAATLGNLY
                     IPKV"
     gene            14913..15860
                     /gene="arcC"
                     /locus_tag="VQU30_001139"
     CDS             14913..15860
                     /gene="arcC"
                     /locus_tag="VQU30_001139"
                     /EC_number="2.7.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003025409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbamate kinase"
                     /protein_id="HET2447255.1"
                     /translation="MANRKIVVALGGNAILSSDPSAKAQQEALVETAKHLVKLIKNGD
                     DLIITHGNGPQVGNLLLQHLASDSEKNPAFPLDSLVAMTEGSIGFWLKNALQNALLDE
                     GIEKNVASVVTQVIVDKNDPAFVNLSKPIGPFYSEEEAKAEAEKSGATFKEDAGRGWR
                     KVVASPKPVDIKEIETIRTLLNNGQVVVAAGGGGIPVVKENNGHLTGVEAVIDKDFAS
                     QRLAELVDADLFIVLTGVDYVFVNYNKPNQEKLEHVNVAQLEEYIKQDQFAPGSMLPK
                     VEAAIAFVNGRPEGKAVITSLENLGALIESESGTIIEKG"
     gene            16069..17580
                     /locus_tag="VQU30_001140"
     CDS             16069..17580
                     /locus_tag="VQU30_001140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004191872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YfcC family protein"
                     /protein_id="HET2447256.1"
                     /translation="MSEKAKKGFKMPSSYTVLLIIIAIMAVLTWFIPAGAFIEGIYEA
                     QPQNPQGIWDVLMAPIRAMLGTHPEEGSLIKETSAAIDVAFFILMVGGFLGIVNKTGA
                     LDVGIASIVKKYKGREKMLILVLMPLFALGGTTYGMGEETMAFYPLLVPVMMAVGFDS
                     LTGVAIILLGSQIGCLASTLNPFATGIASATAGVGTGDGIVLRLIFWVTLTALSTWFV
                     YRYADKIQKDPTKSLVYSTRKEDLKHFNVEESSSVESTLSSKQKSVLFLFVLTFILMV
                     LSFIPWTDLGVTIFDDFNTWLTGLPVIGNIVGSSTSALGTWYFPEGAMLFAFMGILIG
                     VIYGLKEDKIISSFMNGAADLLSVALIVAIARGIQVIMNDGMITDTILNWGKEGLSGL
                     SSQVFIVVTYIFYLPMSFLIPSSSGLASATMGIMAPLGEFVNVRPSLIITAYQSASGV
                     LNLIAPTSGIVMGALALGRINIGTWWKFMGKLVVAIIVVTIALLLLGTFLPFL"
     gene            17602..18933
                     /locus_tag="VQU30_001141"
     CDS             17602..18933
                     /locus_tag="VQU30_001141"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000686986.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dipeptidase"
                     /protein_id="HET2447257.1"
                     /translation="MKIDITNQVKDEFLISLKTLISYPSVLNEGENGTPFGQAIQDVL
                     EKTLEICRDIGFTTYLDPKGYYGYAEIGQGAELLAILCHLDVVPSGDEADWQTPPFEA
                     TIKDGWVFGRGVQDDKGPSLAALYAVKSLLDQGIQFKKRVRFIFGTDEETLWRCMARY
                     NTIEEQASMGFAPDSSFPLTYAEKGLLQVKLHGPGSDQLELEVGGAFNVVPDKANYQG
                     PLYEQVCNGLKEAGYDYQSTEQTVTVLGVPKHAKDASQGINAVIRLATILAPLQEHPA
                     LSFLATQAGQDGTGRQIFGDIADEPSGHLSFNVAGLMINHERSEIRIDIRTPVLADKE
                     ELVELLTRCAQNYQLRYEEFDYLAPLYVAEDSKLVSTLMQIYQEKTGDNSPAISSGGA
                     TFARTMPNCVAFGALFPGAKQTEHQANECAVLEDLYRAMDIYAEAVYRLAT"
     gene            complement(19339..19629)
                     /locus_tag="VQU30_001142"
     CDS             complement(19339..19629)
                     /locus_tag="VQU30_001142"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000501069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2447258.1"
                     /translation="MGALGYYEGFVPYVSNQYKNQAEEEGKPLSDKYIFEKILGKTYA
                     AFKKDQINERVEKLGKLKPITINYNGKSEVIDSKEKLQELMNKAVKDEVAQI"
     gene            complement(19617..19868)
                     /locus_tag="VQU30_001143"
     CDS             complement(19617..19868)
                     /locus_tag="VQU30_001143"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000657761.1"
                     /note="The YSIRK form of extended signal peptide directs
                     nascent proteins to the cross-wall site, while signal
                     peptides lacking YSIRK direct proteins instead to the cell
                     pole. A large fraction of YSIRK proteins are surface
                     proteins anchored by sortase-mediated processing of a
                     C-terminal LPXTG motif; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YSIRK-type signal peptide-containing protein"
                     /protein_id="HET2447259.1"
                     /translation="MKEFQFERKQRFSLRKYAIGACSVLLGTSLFFAGMGDQPVQDTE
                     TSSALISSHYLDEQDLSEKLKSELQWFELENKLLNLWEH"
     gene            complement(20267..21151)
                     /locus_tag="VQU30_001144"
     CDS             complement(20267..21151)
                     /locus_tag="VQU30_001144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001838996.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SPFH domain-containing protein"
                     /protein_id="HET2447260.1"
                     /translation="MIFLIVCVLLLVIVTLSTVYVVRQQSVAIIERFGKYQKVANSGI
                     HIRLPFGIDSIAARIQLRLLQSDIVVETKTKDNVFVMMNVATQYRVNEQSVTDAYYKL
                     IRPESQIKSYIEDALRSSVPKLTLDELFEKKDEIALEVQHQVAEEMTTYGYIIVKTLI
                     TKVEPDAEVKQSMNEINAAQRKRVAAQELAEADKIKIVTAAEAEAEKDRLHGVGIAQQ
                     RKAIVDGLAESITELKEANVGMTEEQIMSILLTNQYLDTLNTFASKGNQTIFLPNTPN
                     GVDDIRTQILSALRAEKK"
     gene            complement(21296..22447)
                     /locus_tag="VQU30_001145"
     CDS             complement(21296..22447)
                     /locus_tag="VQU30_001145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862055.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-containing alcohol dehydrogenase"
                     /protein_id="HET2447261.1"
                     /translation="MAIFYVPAVNLIGKGVVNEVGPYIKELGYKKALLVTDKYIEGSD
                     ILPKTLKPLDTEGIEYVIFSDVEPNPTCKNVTDGVAALQEHRCDFIISLGGGSPQDAA
                     SCISIMATNGGKPQDYEGLHKSAKKGLPVVAINTTAGTSAEITINYVITDEERKVKMV
                     MVDKNSLALISVNDPELMLSKPQALTAATGMDALTHAVEALVTPGAYDVTKKLSIGAI
                     ELIKEYLPRAVENGHDIEAREGMVNAIFLGGMSFNNAGLGYVHSMAHQLGAVYNLPHG
                     VCCAMLLPVIEHENAKRVPEAFRNVAKALGLHVEGKSDQECADYAIVEIEKLSETVGI
                     PKKLTELGIEEKDFDFEYLSKNALIDACAPGNPFMPTLEETIAFYKELF"
     gene            complement(22593..24359)
                     /locus_tag="VQU30_001146"
     CDS             complement(22593..24359)
                     /locus_tag="VQU30_001146"
                     /EC_number="5.3.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002935191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-fucose isomerase"
                     /protein_id="HET2447262.1"
                     /translation="MIQHPRIGIRPTIDGRRQGVRESLEVQTMNMAKSVADLISSTLK
                     YPDGEPVECVISPSTIGRVPEAAASHELFKKSNVCATITVTPCWCYGSETMDMSPDIP
                     HAIWGFNGTERPGAVYLAAVLASHAQKGIPAFGIYGRDVQEANDTDIPEDVKEKLLRY
                     ARAALATGLMRDTAYLSMGSVSMGIGGSIVNPDFFQEYLGMRNESVDMTEFTRRMDRG
                     IYDPEEFERAMVWVKEHIKEGVDRNREDLILSKEEKEKQWEFVIKMFMIGRDLMVGNP
                     RLAELGFEEEAVGHHALVAGFQGQRQWTDHFPNGDFMETFLNTQFDWNGIRKPFVFAT
                     ENDSLNGVSMLFNYLLTNTPQIFADVRTYWSPEAVKRVTGHTLEGCAAAGFLHLINSG
                     SCTLDGTGQATRDGKPVMKPFWELEESEVQAMLENTDFPPANREYFRGGGFSTRFLTK
                     GDMPVTMVRLNLLKGVGPVLQIAEGYTLELPEDVHHTLDNRTDSGWPTTWFAPRLTGK
                     GAFKSVYDVMNNWGANHGAITYGHIGADLITLASMLRIPVNMHNVPEEDIFRPKNWSL
                     FGTEDLESADYRACQLLGPLHK"
     gene            complement(24416..>26062)
                     /locus_tag="VQU30_001147"
     CDS             complement(24416..>26062)
                     /locus_tag="VQU30_001147"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001031112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="discoidin domain-containing protein"
                     /protein_id="HET2447263.1"
                     /translation="NYRTDKTAMWALSGNFDASKSWKKEELELANWISKNYSINPVDN
                     DFRTTTLTLKGHTGHKPQINISGDKNHYTYTENWDENTHVYTITVNHNGMVEMSINTE
                     GTGPVPFPTPDKFNDGNLNIAYAKPTTQSSVDYNGDPNRAVDGNRNGNFNSGSVTHTR
                     ADNPSWWEVDLKKMDKVGLVKIYNRTDAETQRLSNFDVILYDNNRNEVAKKHVNNLSG
                     ESVSLDFKEKGARYIKVKLLTSGVPLSLAEVEVFRESDGKQSEEDIDKITEDKVVSTN
                     KVATQSSTNYEGVAALAVDGNKDGDYGHHSVTHTKADSNAWWQVDLGEEFTVSKVDIY
                     NRTDAEPQRLSNFDVIFLSSSGEEVFRRHFDKVVDGLLSLKVPSVGAKLVKIELKSAA
                     IPLSLAEVEAYGSKRTPKKLSNIALTKETRQSSTDYNGFSRLAVDGNKNGDYGHHSVT
                     HTKGDSPSWWEIDLAQTEELEKLIIYNRTDAEIQRLSNFDIIIYDSNNHEVFKQHIDS
                     LESNNLSIDLKGLKGKKVRISLRNAGIPLSLAEVEVYTYK"
BASE COUNT         7397 a         5822 c         5082 g         7761 t
ORIGIN      
        1 taaagcctat aaccatgcgc tatccaagga gagaagcaag gttgagaaca tctttgccaa
       61 agtaaaaacg tttaaaatat tttcaacaac ctatcgaaat catcgtaaac gcttcggatt
      121 acgaatgaat ttgagtgctg gtattatcaa tcatgaacta ggattctagt tttgcaggaa
      181 gtctattgaa atactaagcc tacacagact gatttcaatt ttaccattct tcatagtcaa
      241 aaccatcata atctggatat tgttctggca acgttccaac cgaacgtacg agataagctt
      301 cttcgtcctc tgtctcgatt tctctcagca cttagcattc aaaacgccat tcatcaccga
      361 agtcgaaaat aaacttaaat ttttgtttga cacttaggct atccagatag acattttcta
      421 tgtaacgttc ttcaacatcg tcactaacaa agctaagaaa gtaagaatct gcatgactcc
      481 actcaacatt atccatgaaa aatgcatgag catgatcatt tgcaaaatcg aaactccata
      541 aaatcacatc tgctagttcc gctaacgttt ttgtttttgg aatctatata tgtcggtagc
      601 aacctttttt aatttgacgg aaatgatcca agcttctaca gatgctggct tttcagcttc
      661 tatttcttgt tttactaatt ttaactgtag catttgaaac cagataattc ttctgtttca
      721 cgcgaaacac cctgcgccaa gcaaggtgtt cttgttttta tactcaatga aaatcaaaga
      781 gcaaactagg aagctagctg caggctgctc aaaacactgt tttgaggttg tagatggaag
      841 ctgacgtggt ttgaagagat tttcgaagag tattaagtcg tataaatcgt cgaagctgtc
      901 gcaatggtat gccactggtt agctgtagtt gctgcgaaat ccttgtctgc gtagaagtca
      961 gtaaatggta ggatttcaac ttccagctcg tcgatgcggt caagctggcc agccagataa
     1021 acctcgatac ggctttctgc tcgtttgatg cgttgcaaga gtccgcccat acggatgtca
     1081 actgtatcca aaccaaagac cttgttttct ttcagccatt ggtgactaaa gagggcatgg
     1141 aagtcttcaa tttggcttct aagttctggt aattcttgtc tggcgatttg ttgtaaactt
     1201 tctttatcat ccgcttggta ggcctgacga atgcgtcgtc ccacatctac tttgctactt
     1261 aaaatagcat tcaactgggc ctgagtttca aagagataag catagtttcc agctttttct
     1321 ttaatgttag caagcgtctc agcagcctga gcgaagtgcg gtttgtcctg ttcaggtgtc
     1381 atgtgttgat caagaatcgg acaaagaata tcctgataaa aaacatagcg gttgggattg
     1441 ataccgctga gattgcctgg taggtctggt aagaggttgg caaggtcaat ctgcataaaa
     1501 tcctcaaccg ttagaccagt attggtcttg aagtgcgcag acaaaccatc taggtcattg
     1561 cgatagctga gttctgccca gatttgcaag cttggtagga tagagaactg ggcagtttca
     1621 ccaccattgt ctccccaacc cgttacgatg acttctttaa tctgattggc acggcaggct
     1681 ttattagcct cgatagccac tagacggcta aaatggttgt gaggtgtaaa gccaatccac
     1741 ttccaagctc cccctgcaaa tgcaaggtca tggctaatct tgtgatgatt gcggaaatta
     1801 cggttgtatt tttcctcgct atcctgataa taatcccagt aaaccagagt cacacggtct
     1861 ttgagacggt ctaggtagac acgagtttcc tctggaattt ccacatcacg gtcgtactgg
     1921 ccatccgctg acatgagttt gaagaacata tcactccaca tctggcagtg gaaaccatat
     1981 ttgtcagcaa tatccagcac gcgctccaag tgttggcaca tgaggagact acgatccaca
     2041 acaccgttca aaatcaggta gcgtcccaaa ccaaccaagt gggcttcgtc catcccgata
     2101 ttgaccttgc gagtcttcag tttagacaac gtggcaaaca tgccatcaat caggtcataa
     2161 accttttctt cgccaatgag aagaatgtcc tctacatcac ggagctcctg cacttccttg
     2221 acaccccatt tgacaaaggc cgacaagtgg gccaaggtct ggatgcatgg tacaaaggtc
     2281 atgtcaaact gttgagcata ggcttcgatt tcctgcaact cctctgctga ataagctcca
     2341 cggaaatagc caaagtaagg ctgcccttca atctggtaag tgtcttccat gtaaagttca
     2401 aaggttgagt agcccatgag agccaagacc tcaatcatct gcttggcaga agccacattc
     2461 agcaccgcat ttcgagaaca gtcaaccatg taagccaaat cttcgtaagc tgcttgttcc
     2521 tcaatctcta ctttatcagc ttctgctaga actgttacca acaaggataa ggcacgataa
     2581 agttggtgag gtttgcggta ggtcaattga tagtgacctt cctcaccctg gatagagata
     2641 gaggcttggt cagactgagt gacagccact tccacatctg gtagagaaat atgacctttt
     2701 aaaacctcaa tagcttgcgt ttgtttggga ctaagtcctg taaatcttac cattgctttt
     2761 cctcctgtag ccagttgaca agagcaccgt agagattggc atctgcgtga taggtgcagg
     2821 cctggataac tggtgcgacc gtgtattctt cgtaggtatc gacaaagtta tcaacagcct
     2881 tcttgacatc ttggataaaa tctggatttt gactgataga gccacccaga ctgatgacat
     2941 ctggatcgat cagatactgg atattgagca agccttgcgc cagattgcgg ttcatgcgct
     3001 caatggcttc ttgacaaagg atattaccag ctgcggcctc ttggtaaatc ttgcgaccgt
     3061 cccaatcagt atgaccagat ttttcaatca cgtatcgtac catattccca gttgatgcta
     3121 gttgcgacca gttattaagt ttttcagcag gggcaagggt tgtcatgtag ccaaattctc
     3181 cacccaagcc gtggcgacct cgatgaagtc taccattgat aatcatggct ccgccaatcc
     3241 ctgtcccaat cacgacacag gctgcatttt caagatctgg atgagctagt agttcactga
     3301 gtccaacgca gttggcatca ttttctaaat ggacaggtag ctgataagag ctaagcgcct
     3361 cataccaaga aaagccatgg atgtagggca ccgcactgaa gccatcaatc acacctgtct
     3421 cttgattgac tgcacctgga acgctcatag caatcccact gtaatcctgt tctgacaagc
     3481 gttgatctag ccacgctagt aaatcctcca agttttcagg cgttgaaata cttgtcttat
     3541 ccagtatttt cccatcagga gtcagactgg caaacttaat cccagtccct ccgatatcaa
     3601 tcgttgcaat ggtcattgtt tttaccataa aaaggggcga atcagcagtt agttcttact
     3661 ttttcgcccc tcctttcttt tgatgtttac tttttgaaat taaatttctt cttttttgat
     3721 gaattctgta cgaatctctt gtggatccaa tggtcctgaa tgaactggat atggtcgctc
     3781 aagtaagtca agaatggttt gttgatgttc tgatatgtgc acattttctt gactcatatt
     3841 atagtaacgg aagacatagc cttcttcatt ttccgccact ttaaaggctg ttggacaaac
     3901 ttgcggtatg ctgagaacag aatggctcaa gaggctacca gtcgcaacca cgcttccttc
     3961 ctgtctagca agctgaaggc tggtaaacgg tgtctgcaag gctttggcac gacggaaagc
     4021 tgaaaagcgt tcttgggctt ggtggcattc aagtgcaaac tcgacttcaa actcacgcaa
     4081 gcattgtgct tctggcgttg ggaagtagcc ccagtcacct agctcacctg atgcacgcaa
     4141 aatggtcacg gcaatggtgt tatccccaag gatttcgtat tcattcaatc ccttattgga
     4201 tacagtcacc cctttttcat cgtcatacag actgacaaaa gcttgttggt gttgaggatt
     4261 ttcaggattt tcccatgaag cagctggttt gtttggtcgt gtcaccacct catagatact
     4321 ttcagaatca ttgcttggac gcgtgttatg agtcttgacc aagagacgga tacggtgatc
     4381 cttggcagtg ttagtaaagc gagtcttgaa gcggatttgt ggattgtcaa caaagacaat
     4441 caactcagtt tccagaggaa tgtttgtcaa ttcttctgac cgtccagcct cacgcttcat
     4501 aaactcgatg ataccttgtt gctcttcttc tagcttttca tccgcactga caggcacggt
     4561 caattcatgt ttgagcaaga ttttagcata gcgatctgtg ttttccaaga cctcgtggcc
     4621 cttaagctct gcaaagattg gctctgttcc ttttggttgg aaatagatat actcgtttcc
     4681 gatgtcccca cggtcttcga agcggataaa gtcttcatag gcttcgtgag ttgtcttgtc
     4741 atatactgtg atattgtcat ccacactcac cgttacgaat ggtgtatcaa tcactccgtt
     4801 ttggtaaata ccctcacggt gttcttgttt tccttccagc aattggaagg ttgtccaaga
     4861 aagcggcgct aggtgaactg gaatggtcac gcgcacttgt cgagcaatac gagcttggcg
     4921 gaacttgtct tttggtaaat cgtactcaaa attagctccg aggtcttcga ttgtagcctc
     4981 tacaggacga ccatccaagt cctccacacg gtaacttggt aagataagag cagccatctt
     5041 tttgtagcct tctgttgggt gcaattcctt gaaatcacaa gtcgccacat caatcactgt
     5101 gctgacagta tcgaccttat catgcaagcc tgtgttaatg acagtaaaga gatagtcact
     5161 ttgagcctta tccgtagcaa ttttaccctt ccactcgttg agcaagttac ttttaacaaa
     5221 gtttcctact tggttgacct tggcaaaacg cgtttccatc tcgcggtgaa cttcgtccac
     5281 gctacagcca cagatactat catgtggcgc attctgcaaa agtgttttcc aagcataggt
     5341 caactggtcc ttgtggttgt gtccaccagt gataatagtc aagggttcta ccacttgctc
     5401 taggaggttg ctattttctt ggaaggcttg ttttaggtaa atgcgggatg aagaagtgtt
     5461 ggcaagtgtg taccagccat ctgtttcctg actggtcaac tcgcctgtaa cagttgataa
     5521 gtgttcagga agcgcacctt ctacagcttg aacatattca tcaaaagaac tatgaacaaa
     5581 gattacatcc gggaagagtt catttgccac acgaatggct tcgctcagat ttttctgtac
     5641 aggctggtgg tcacagccgt tcatcatcaa ccattggttg gtcgaagcgt aggcacgcac
     5701 atctgacaat ttttgtttcc agaaggtcaa ggcctcatct ttgtcaactg ggatttcatt
     5761 cccattactg taccagttgg caaagagaat acctaaaaca cgactaccat ccacaccctg
     5821 ccagtacatt tctgaaaact gggatgtaaa ccgctcatct tcaaggactt ggttgtcaaa
     5881 tccaatcggc ttcacaccac gaccaaaggc tgccacgtga atacctgatt tttgaaggat
     5941 ttgaggagct tgtcccatat ttccaaaggt atctggaaag tagccaatct gggttgattt
     6001 accccatttg gcagcttctt gttgaccaat caaggtattg cggacattgg cttcactgga
     6061 gatcaagtag tcatcctgca agatgtaaaa gggaccaatt ttaagtttgc cctcgtcaat
     6121 gtagcgttgg accttgtcgc gattttcagg gcgaatttgt aagtagtcat caaggacaat
     6181 agtttgtcca tccaagtgga aactcttgaa ctcagggtca ttttcaaaga gatcaaagag
     6241 attgtcaaac aattccacca actgcatacg atggctttca aaaggcaagt accactcacg
     6301 atcccagtga ctatgtgaga taatatgtac aacaacattt tccatgaagt aaaacctcat
     6361 tctaaattta aattttaacg ttttaaatgt aaacttgtga ttctgataag aatcggttga
     6421 gctaaagcga gccccttagc ggatatccaa gtaatccaag accaactcac agaacatcat
     6481 gttagcccag gagaaccatt cacgagagta gagggtcgga tcatctacgt ggaagctttc
     6541 gtgcatgaca cctgtaccac catcgcaggc aaccagctga tccagcaaga attttttctc
     6601 tgccttatct cttgttgtca atccttggat agaaagggcg attggccaga tatagcgata
     6661 gaaggtatga gaacttccga gaccgctagc gtattctcct tggtagaagt atggattttc
     6721 agagctcaga atggtacggc gagtggcttg atacacttca tcatcgatcg aacagtagcc
     6781 cagatagggc gcagctagta gacttggtac atttggatca tccatgatgc tggcatttcc
     6841 taggccatct acttcaaaag cgtaaatctt ttcgcccttg ctgttggtgg tgtaagcgta
     6901 gttttcgatt ccttcttgga tttcatcctg aagacgcttg gcatcagcaa taacactctg
     6961 gctatcagct aggtttaatg ctgcgaagat ttcttgcaca taacccaaga ctactacagc
     7021 aaacatattt gacggaatca agtaactata ctggcaacag tcatcactcg gacgaaaagc
     7081 tgaccaagtc atacctgtca ctgcaaagtc aggtccaaag ccatcattta ccaaggtgtc
     7141 ttccttacgg tccgtatctc ggacaaaacg ataaggagag ttcttgtggt cttgttcaac
     7201 tgtccataga tggagaattt ccttagtcgc tgcgacaaaa gtttcatcaa actgactagt
     7261 ctcgccagtc tctttccaga ggagataagc caactgcaaa ggatagcaaa gcgaatccac
     7321 ctcatacttg cgctcccaga tccagccgtt aaggtctgtg tggtcagtct cgtggtgccc
     7381 tttccagttc tcctcaatgt tgaaggagtt agcataggga tccttgagta ccaaggtcat
     7441 ctgacgtttg accaaacctg caatggtctg acgcaggagg gcatctcttt tagctacatg
     7501 aaggtagggt ctgagttggg ctgtcgaatc tcgaagccac atggcaggaa tatccccagt
     7561 caagacaaaa gttgaaccat cttctaagat ttcaaccgta ttgtccaagg tatcggtgta
     7621 gcaacgctca aagacatcaa cccactctgg atggtccttg gcccgctctg ctacttcatc
     7681 tagccattct ctaacaattt ctttcgaata aatcatcgtg caattccctc tttcaaacaa
     7741 gtttcatgtt cagtatatag cttttgagac agaaaataca tacacaaatg atagtcattt
     7801 ttctacaaaa tagttatctt taaaactcct tttctaaagg ccctcttttt ctgatataat
     7861 gtagaaaaac agctaaagga aagactatga aaccactact tgaaaccatc gatacccgct
     7921 ttggtactgc tagcaagcat gccttctctc ggggaaatac cctgccatac acaggcgtgc
     7981 cttttgggat gaattacttt gtgccccaga ccagtgacca ggatggatct tggttttttg
     8041 atccgcatct gcctatcttt caggggattc gattaactca ccagcccagt ccttggattg
     8101 gggactactc ttggctcctt ctgacacctg tcaccagtca actgggggga gacagcctct
     8161 ttcaccgcca gtcttcttat gatatagata aagcttgctt ccagcctcac tatttgaagc
     8221 tcttttctct gcgttatcag attgaaaccc agctcacacc gacttgctat ggtgcttcta
     8281 ttcgtttgaa tcaaaagcaa ggcaaagccc tctccctcta tcttcacgca gcagatgaac
     8341 tgacagtaga gcaagtagat aagcggactc ttgccctgcg acaagaaggt aaaactgaaa
     8401 ctaacaaaaa ttcgctaacg atgttcactg ccctgcaaat gaacacggat attcttgcta
     8461 tcagccaaga agctggggac tggcgaattg acttagcaag tagtcaaacc gagatgcaac
     8521 tagccacttc tttcatctct ccttctcaag ctctaatcaa tctacctcaa gaagattttg
     8581 atagctgtaa aacaagtgcc caagcggatt gggaaaatct cctccatcgt tttgacatta
     8641 tagagacagg agaggctgac cgaaccttct ttgaccactg cctctacaga ctcttcctct
     8701 tcccacagac tttttatgag gttgatgagt cagggaaagc catccacatg gatctggcta
     8761 ctggtactgt caagcctggt gtcctcttta gcaacaatgg tttctgggat accttccgca
     8821 ccaccttccc cctctttgcc cttatcatac cggagcacta tcaacgcttt ttagaaggtt
     8881 tcctcaatag ctaccgcgat actggtttcc ttccaaaatg gctggctcca gatgaacggg
     8941 gtatgatgcc aggtacactg ctagatggca ttatcgcaga tagcgcctgt aaggacatgg
     9001 cccccgacct agaaggagaa ctcttccaag ccatgctcga aacagccagc aaagccgacc
     9061 ctctcggcat caatggccgc cacggactag cccaatacca agaactaggt tacctctcta
     9121 ccgaccacca cgaaagtgtt agccatactc tagactatgc ctatagtgac ttttgtatcg
     9181 ccagctgtgc caaaaaacta gagaacatag aaatcgctga aacctacaag gctgcttcac
     9241 aaaattaccg ccagctattt gacgctgaga caggttacat gcgagcacga gacaatcaag
     9301 gaaactttca ccctgacttc tctccttata gttgggggcg agactacgct gaatgctctg
     9361 ccattcaagc tactttaggc gttctccacg acatccctgg cttaatccaa ctgatgggtg
     9421 gaaaagaaac ctttagcaac tatcttttga aagcctgtca agatgctccc ctctttgaaa
     9481 caacaggcta tggttacgaa attcacgaaa tgagcgagat ggctactgct ccttttggac
     9541 aaatagccat ttccaaccag cctagtttcc acattcctta tctcttccgc tacagcgatt
     9601 accctgacta cactgccctt cttatcaaga cgctccgtca gaaagctttt cacccaagtt
     9661 gggaagccta tcctggagat gaagacaatg gtagtctctc tgcttggtac atctggtcag
     9721 ctctcggatt ttatccaacc tgtccaggaa aaccaagcta tgatctcgga atccctctct
     9781 ttgaccatct acgagtctac ctagctaaag aaaataaatg gctagatatt catactgagc
     9841 aaaaccacag ccattttaac tttgtcaaag aatgccgact ggacaaaaca ctcgtatcaa
     9901 ctattcaaca ccaagacctc ctaaaagctg aacaactaac tttcaccctc agctggctac
     9961 caaatcacta ataaccaaaa gaacctttgc atcgcgcaaa ggttcttctt ttatgaaact
    10021 tggacttgaa gttgatccac aagctgacca tccaccgtta ggttcagata gaaatccaag
    10081 gttttatctc ctgcgaaata caaggttggt agcgtcagcc ttttttcagt ctcaccagct
    10141 tgaaacgcaa ggacataaat ctcgtcctga taggcgacac catggacacc tgtccccggt
    10201 tgaatcgaaa tcttagcctc taaagaggag ctactttcac tacgttcaat cctaaaatga
    10261 agagtctctc cctttgccac agctaggctt ttttctgcaa atgctagttc ctgaacaact
    10321 tctttttttg ataacccagg agttttataa agggaaatct tggtcaatac agggatagat
    10381 tgtgcctcgg taatcatcac gcgcaccttt tgtgcctcta ctagcggacc tcgcaagagg
    10441 cgcttatgac caactgtgaa gcccctgcca aactcctgcc agacaccatc cacctctact
    10501 tgcacatgaa aagcagcgat tcgttgccct agcttcaaat cttctcttaa ctcaattaca
    10561 tcaaaagttt taggagaacc taaatcgagt tctaactgga tgggcaagtc tgcatcgctt
    10621 gcccaagagc tggtctcaag gccgtctgtc aaatggcgac aatcaaagtc tgcggaaaga
    10681 gctggaccag atacctcagc tcccagagcc aaatcttctt tatagagctc attgcgatag
    10741 gtcgcaaatt cataaagtcg ttcaatatcc tttgcatcaa agagcccagc ttgattcggc
    10801 ggaatattaa gcaagagtgg agttcctcgc cctactgagt gaaagtagat ttcgaccaac
    10861 tcctcgagag acttaggatc ctgatcctca tggtagaacc agcctggacg gatggaaaca
    10921 tctgcctctc cgattgaaaa aatcgtgccc gagggatccc cgtgctgaag atagttcagc
    10981 tctgcttctg ttcctagttt atcaagattc accttttgcc acagtggatc acctgcatac
    11041 cctcgttcat tgccaatcca gcggatactg gtgccttctg ttgaaaaaat caagcaatcg
    11101 ccctgcaggt cacgaatggt ttcaaaccat ttttcaaatt cataattaac cttttgcgcg
    11161 ccctctcctc tggcaccatc catccaaacc tcagcgaact taccagcatt cccatagtta
    11221 ggatttgata agatttcctt caactgagcc agataatagg cattgtagtc cgcttctcgg
    11281 tccacatgat agaggggact atgggcatcc cacggtgaca ggtagacccc catatccata
    11341 tcaaactctg tggcagcttg ggatacttca aggagcaagt cgccctttcc tctcctccaa
    11401 ggactgacct taaccgaata atctgtgtga gctgtcggat aaaggacaaa gccatcgtgg
    11461 tgcttgacca ccaaaatcaa ctttttgaag cccgtttcct tgagcacacg aacccactca
    11521 cgcgcatcca actgactcgg gttaaagcgc tcaggatcct cctgtccagt cccccattct
    11581 tggtcataaa aggtattagg accgaagtgg ataaaagctg ctagttcatc tcccagataa
    11641 gctagctgag tctgacttgg taacggtcca tgcggtttga ttttcttcat cgttatatat
    11701 ctccttcttt tgcaacttct cttgttcaca aggttatcca caggttgtgg ataataaacc
    11761 atgatctaac agccagctct ttccaactcc aactggtagg ctcaggattt ttctcctcaa
    11821 tgttccctct tcaaacagct ctgtcatatg gttctgctaa cacctctcag aatgctactc
    11881 tccataatta ttctcaggct tctttcaggt cattgtgtga agaccattca ctctccagac
    11941 ttttccacag attgtgaata agtgattatt ctaagctatc acctcgtcga ctataacaaa
    12001 aaataaaaag agggtcaata agataattat ctcttcctaa atactcagaa aagattctat
    12061 aatttgtaca attgaacaag aaatgcttct ccaaaatcta tcttcaaaag aatgttgcat
    12121 ctttttatcc tttcacacaa acatttctct ttatacagat ccaagtgata accagatgat
    12181 aattggacac tttttggtca tttgtatatt ttttgaaaaa ttttttaaaa aaattttata
    12241 tcctttttat agaagtttat gcatttgtat ctatgtattc tatcctatgt tatgtataat
    12301 aacataaaat tgtgctaaac atcataattt atattatttt ccgagaaatt atagccattg
    12361 acattaccta ggaattgcgt tataacatac atgtaagcgg tacccaaaat ggtgccaagt
    12421 caaaattttt aaggaggaaa atacatgtct tctcatccaa ttcaggtctt ctcagaaatt
    12481 gggaaactga aaaaagttat gttgcaccgt ccaggcaagg agttagaaaa cttgttgccg
    12541 gactatcttg aaaggcttct ttttgatgat attcctttct tggaagatgc tcaaaaagaa
    12601 catgatgcat ttgcccaagc tcttcgcgat gaaggaattg aggttctcta cctagaacaa
    12661 ctcgctgctg aatcattgac ctctccagaa atccgcgatc aatttatcga ggaatactta
    12721 gacgaagcca acatccgtga tcgtcaaacc aaggttgcta ttcgtgaatt acttcacggc
    12781 atcaaggaca accaagaatt ggttgaaaaa acaatggctg ggattcaaaa agttgaattg
    12841 ccagaaattc ctgacgaagc taaagatcta actgacttag ttgaatcaga ttatccattt
    12901 gcaattgacc cgatgccaaa cctctatttc actcgcgacc catttgcaac aattggaaac
    12961 gccgtatcgc ttaaccacat gtttgcagat actcgtaacc gtgaaacact ctacggtaag
    13021 tatatcttca aataccaccc aatctatggc ggaaaagtgg atttggtcta caaccgtgaa
    13081 gaagatacgc gtatcgaagg tggagacgag ctaattcttt ctaaagacgt ccttgcagta
    13141 ggtatctctc aacgtacaga cgcagcttct atcgaaaaac ttttggtcaa catcttcaag
    13201 aaaaatgttg gcttcaagaa agttttggcc tttgaatttg ctaacaaccg taaattcatg
    13261 cacttggata ctgtcttcac tatggtagac tatgacaagt tcactattca cccagaaatc
    13321 gaaggcaacc ttcacgttta ctcagttact tacgaaaacg aaaaacttaa aattgttgaa
    13381 gagaaaggtg acttagctga acttcttgct caaaaccttg gtgtagaaaa agttcatttg
    13441 attcgttgcg gtggtggcaa tatcgtagca gctgcgcgtg aacaatggaa cgacggttct
    13501 aacactttga ccatcgcacc tggtgtggta gttgtttatg accgcaatac cgtgaccaat
    13561 aagattttgg aagaatacgg gcttcgcttg attaagattc gcggaagtga attggttcgg
    13621 ggccgtggtg gacctcgttg tatgtctatg ccatttgaac gtgaagaagt gtaatcgctg
    13681 ttcggtattc gtcaatagaa aatgtaaaaa atagaaagag gaaataataa aatgacaaat
    13741 tcagtattcc aaggacgcag cttcttagca gaaaaagact ttacccgtgc agagttagaa
    13801 taccttattg gtctttcagc tcacttgaaa gatttgaaaa aacgcaatat tcaacaccac
    13861 taccttgctg gcaagaatat cgctctccta tttgaaaaaa catctactcg tactcgtgca
    13921 gcctttacaa ctgcggctat cgaccttggt gctcacccag aatacctcgg agcaaatgat
    13981 attcagttgg gtaaaaaaga atctactgaa gatactgcta aagtattggg acgtatgttt
    14041 gacgggattg aattccgcgg attcagccaa cgtatggttg aagaattggc agaattctca
    14101 ggcgttccag tatggaacgg tctaactgac gaatggcacc caactcaaat gctcgctgac
    14161 tacttgactg ttcaagaaaa cttcggtcgc ttggaaggct tgacattggt atactgtggt
    14221 gatggacgta acaacgttgc caacagcttg ctcgtaacag gtgctatcct tggtgtcaat
    14281 gttcacatct tctcaccaaa agaactcttc ccagaaaaag aaatcgttga attggcagaa
    14341 ggatttgcta aagaaagtgg cgcacatgtt ctcatcactg aagatgctga tgaagcagtt
    14401 aaagatgcag acgttcttta cacagacgtt tgggtatcaa tgggtgaaga agacaaattc
    14461 gcagaacgtg tagctcttct taaaccttac caagtcaata tggacttagt taaaaaagca
    14521 ggcaatgaaa acttgatctt cctacactgc ttgccagcat tccacgatac tcacactgtt
    14581 tatggtaaag acgttgctga aaaatttggt gtagaagaaa tggaagtaac agacgaagtc
    14641 ttccgcagca agtacgctcg ccacttcgat caagcagaaa accgtatgca cactatcaaa
    14701 gctgttatgg ctgctacact tggtaacctt tatattccta aagtataatt ttagataata
    14761 aaccgtctac caacagctat gagggctgcg actaatagct ttagtccggt cctcttttat
    14821 gtaatggtaa tctattattt cttataaaat atgtgaaaaa tcattaaatt gaaatctaaa
    14881 cgcattctat tgagtgtgat aaaggagaat ttatggcaaa tcgtaaaatt gtagtagctt
    14941 tgggaggaaa tgcgattctt tcttctgacc catcagcaaa ggctcaacaa gaagctttag
    15001 ttgaaacagc taagcatctt gtaaaattga ttaaaaatgg agatgatttg attatcactc
    15061 acggtaatgg acctcaagtt gggaatctct tgctccaaca tttggcatca gactctgaaa
    15121 agaaccctgc cttcccactc gactcacttg tcgctatgac agaaggtagc atcggtttct
    15181 ggttgaaaaa tgctttgcaa aatgctctct tggatgaagg catcgaaaaa aatgttgcct
    15241 ctgttgtaac gcaagttatc gtagataaaa atgatccagc ttttgttaac ttgagtaaac
    15301 caatcggtcc tttctattca gaagaagaag caaaagcaga agccgaaaag agcggagcga
    15361 ctttcaagga agatgctggc cgtggctggc gtaaggtcgt tgcctcacca aaacctgttg
    15421 acatcaaaga aattgaaacc atccgtactc ttttaaataa tggtcaagtc gtcgtagctg
    15481 caggtggtgg cggtattccc gtcgtcaaag aaaacaatgg acatttgact ggtgtcgaag
    15541 cggttattga taaagacttc gcttcccaac gtttggcaga attggttgat gcagacctct
    15601 tcatcgtttt gacaggtgta gattatgtat ttgttaacta caacaagcca aaccaggaaa
    15661 aattggaaca tgtgaatgtt gcccagctgg aagaatatat caaacaagat cagtttgcac
    15721 caggtagcat gcttccaaaa gtagaagcag ctatcgcttt tgtcaatggt cgtccagaag
    15781 gaaaagcagt tattacttcc cttgaaaatc taggcgcctt gattgaatct gaaagcggaa
    15841 caattattga aaaaggataa gttgttttac taataagatg tattctattt ctagtatctt
    15901 tatatcaaat tagaaattat tcttgaaaac atgtacaata tttcaaaaga tactagtttt
    15961 agactttaat atggtaaaac aaatataaat agaaagcgtt ttcttgaatg tttatttaag
    16021 aaagtagttg gttttttaca ctttgttaga catcaggagg aaaaacaaat gagtgaaaaa
    16081 gctaaaaaag ggtttaagat gccttcatct tacaccgtat tattgataat cattgctatt
    16141 atggccgtgc taacttggtt tatccctgcg ggggccttta tagaaggtat ttacgaggct
    16201 cagcctcaaa atccacaagg gatttgggat gtcctcatgg caccgattcg ggctatgcta
    16261 ggtactcatc cagaggaagg ttcgctcatt aaagaaacga gcgcagcgat tgatgtagcc
    16321 ttcttcatcc ttatggttgg tggtttcctt ggcattgtca acaaaactgg tgctcttgac
    16381 gtagggattg cctctatcgt gaagaagtat aagggccgcg aaaaaatgtt aattttggta
    16441 ttgatgcctt tgtttgccct cggtggtaca acttatggta tgggtgaaga aacaatggcc
    16501 ttctatccac tccttgtgcc agttatgatg gccgttggtt ttgatagcct gactggtgtt
    16561 gcaattattt tgctcggttc tcaaatcggc tgtttggcat ctactctgaa tccatttgcg
    16621 acaggtattg cttcagcgac tgcgggagtt ggtacagggg acggtatcgt acttcgtctg
    16681 atcttctggg ttaccttgac tgctcttagt acttggtttg tttaccgtta tgcggataag
    16741 attcaaaaag atccgactaa gtcactggtt tatagtactc gcaaagaaga tttgaaacac
    16801 tttaacgtag aagaatcttc atctgtagaa tctacactta gcagcaaaca aaaatcagtt
    16861 ctcttcttat ttgtgttgac attcatcttg atggtattga gcttcattcc atggacagac
    16921 cttggcgtta ccatttttga tgactttaat acttggttga ctggtcttcc agttattggt
    16981 aatattgtcg gttcatctac ttctgcacta ggtacttggt acttcccaga aggcgcaatg
    17041 ctctttgcct ttatgggtat cctgattggt gttatttatg gtcttaaaga agataagatt
    17101 atctcttcct tcatgaatgg tgctgctgac ttgctcagtg ttgccttgat cgtagcgatt
    17161 gctcgtggta ttcaagttat catgaacgac ggtatgatta ccgatacaat cctcaactgg
    17221 ggtaaagaag gcttgagcgg tctatcttca caagtcttta tcgttgtaac ttatatcttc
    17281 tatctaccta tgtcattctt gatcccatct tcatctggtc ttgccagcgc aactatgggt
    17341 atcatggctc cacttggaga atttgtaaat gtccgtccta gcttgattat cactgcttac
    17401 caatctgctt caggtgtctt gaacttgatt gcaccaacat ctggtattgt gatgggagct
    17461 cttgcacttg gacgtatcaa cattggtact tggtggaaat tcatgggcaa actcgtagtc
    17521 gctattattg tagtgaccat cgcccttctt ctccttggaa ccttccttcc attcctataa
    17581 aatagtgagt gaggtgattc catgaaaata gatataacaa atcaagttaa agatgaattt
    17641 cttatatcat taaaaacctt gatttcctat ccttcagtac tcaatgaagg agaaaatgga
    17701 acaccttttg gacaagcaat ccaagatgtc ctagaaaaaa ctttagagat ttgtcgagac
    17761 ataggtttca ctacctatct tgaccctaaa ggttattacg gatatgcaga aatcggtcag
    17821 ggagcagagc ttctggccat tctctgtcat ttggatgttg ttccatcagg tgatgaagca
    17881 gattggcaga caccgccatt tgaagcaact atcaaagacg gctgggtatt cggacgtggt
    17941 gtccaagatg ataaaggccc ttcgctcgca gctctctatg cagtaaaaag cttgctggac
    18001 caaggtattc agttcaaaaa gcgcgtacgc tttatctttg gtaccgatga ggaaaccctc
    18061 tggcgctgca tggcacgcta caataccatc gaagaacagg ccagtatggg ctttgcacct
    18121 gactcatctt ttcctctgac ctatgctgaa aaagggcttc tacaggtcaa acttcatggc
    18181 cctggatcgg atcaactaga gcttgaagta ggaggcgcct ttaacgttgt accagacaag
    18241 gccaactacc aaggtcccct ctatgaacag gtttgtaacg gtctcaaaga agctggttat
    18301 gattaccaat ccactgaaca aaccgtaacg gttctcggag tgccaaagca tgctaaggat
    18361 gctagtcaag gtatcaatgc tgtcatccga ctagctacca ttcttgctcc tctccaagaa
    18421 caccctgctc tcagttttct tgcaacacaa gcaggtcaag acggcacagg aagacaaatc
    18481 tttggtgata tagcagatga accttctggt cacctatcct ttaatgtcgc aggtctcatg
    18541 atcaatcatg aacgttctga aatccgtatt gacattcgga ctcctgtctt agctgacaag
    18601 gaagaactag tagagttgct tacaagatgt gcacaaaact accaactccg ctacgaagag
    18661 tttgactatc tagcgcctct atacgtcgca gaagacagta aactcgttag cacactgatg
    18721 caaatctacc aagaaaagac tggcgataac agtcctgcta tttcatccgg tggtgccact
    18781 tttgctcgca ccatgccaaa ttgtgtagcc ttcggcgcct tattcccagg agcgaagcag
    18841 acagaacatc aggcaaatga atgtgccgtt ctagaagatt tgtaccgtgc tatggatatt
    18901 tatgccgaag ccgtctatcg acttgcaact taatcaggca actgtttcta ccaaaaaaaa
    18961 tcgaccgatt aatgaactgc accccaaaag ttagacagaa taaatctaac ttttggggtg
    19021 ttttattatg aaattgagtt atgaagataa agttcagatc tatgaactaa gaaagcaagg
    19081 acaaagcttc aaacagcttt caaaaagatt tggtgtggat gtttctggtc taaagtcatc
    19141 tgaatctttg agatgagctt tataaatcgc ttttttcagt ttttgcactg gtgtttcgat
    19201 aaactcaaac tttttagccg tggtattgcc tgattttata gtatattgaa actagaatag
    19261 tacacctcta cttctaaaac atttttagaa atcgatttga ctgtcctgaa cgatttgtcc
    19321 tgttcttatt tcattttact atatttgagc cacttcgtct ttaacggctt tattcataag
    19381 ctcttgtaat ttttctttac tatcaattac ttctgatttt ccgttgtaat ttattgtaat
    19441 aggttttaac ttacctaatt tctcgacacg ctcattaatt tgatcttttt tgaaggctgc
    19501 atatgttttt cctaagattt tttcgaaaat atatttatca gatagcggtt tgccttcttc
    19561 ttcagcttgg tttttgtatt gatttgaaac ataaggaaca aatccttcat agtaacctaa
    19621 tgctcccata agttcaaaag cttgttttct aattcaaacc attgcaactc agatttcagc
    19681 ttttcagata aatcctgctc atccaaataa tgacttgaaa ttagtgctga actcgtttct
    19741 gtatcctgta caggctgatc acccatacca gcaaaaaata aactcgttcc tagcaagacc
    19801 gaacaagctc ctattgcata tttcctcaaa gaaaaacgct gctttctctc aaattgaaat
    19861 tctttcatcc catctcccat cattcattat tactgtatat tttgtatatc agaaatagtt
    19921 tgtattcaca aatctttcta gttattccct tatcattcct aattaaggga ggtaacatac
    19981 aataattttt agttaaatgt atatctatgt tttttgtttt tcttaataaa cgcaatacaa
    20041 aaagagcctg ttgccaagct ctttgtactc aatgaaaatc aaatagcaaa ctaggaaact
    20101 agccacaggt tgctcaaaac accgttttga ggtagtagat aagactgacg aagtcagctc
    20161 aaaacactgt tttgaggttg cagatagaac tgacaaagtc agtaacatct atacggcaag
    20221 gcgacgctga cgtggtttga agagattttc gaagagtatt agtctattat ttcttctcag
    20281 cgcgaagggc tgacaagatt tgtgttcgga tatcatccac accatttggc gtatttggta
    20341 aaaagatggt ttgatttcct ttagaggcaa aggtattcaa ggtatccaaa tactggttgg
    20401 tcaagaggat agacatgatt tgttcttctg tcatgccaac attggcttcc ttgagttcgg
    20461 tgatagactc tgccaatcca tccacaatcg ccttacgttg ttgggcaatc cccacaccat
    20521 gaaggcggtc tttttctgct tctgcttcag ctgcagtgac aattttaatc ttgtcagctt
    20581 ccgccaattc ttgtgctgcg acccgcttac gttgcgccgc attgatttca ttcatggatt
    20641 gcttaacttc tgcatccggt tcgactttgg taatcaaggt tttcacgata atgtagccgt
    20701 aagtggtcat ttcttctgct acttggtgtt gaacttcaag ggcaatctca tcttttttct
    20761 caaacaattc atccaaggtt aattttggaa cagaagagcg aagagcatct tcgatataag
    20821 atttaatctg agattctgga cgtatgagtt tatagtaagc atctgtcacg ctctgctcgt
    20881 tgacacggta ctgagtcgct acattcatca taacgaacac attgtccttg gtcttagtct
    20941 caaccacaat atcactttgc aacaagcgca actgaatccg tgctgcaatc gagtcaatcc
    21001 caaaaggcaa gcgaatatga ataccgctat tagcaacctt ttggtatttc ccaaagcgtt
    21061 caataatcgc caccgactgc tgacgaacca cataaactgt actcagtgtg actatcacca
    21121 ataggagcac acaaacaatc agaaaaatca tgaaaaatat tgccataatg gaacctccac
    21181 aagtattttt ctagtattat agcacattta aagaaggctg tgccgttttt actgcgattt
    21241 ttcctgaaat gtcaataatt agaggtgaat tgtcctattg tcgtccaatc tcttgctaaa
    21301 ataactcttt ataaaaggca atcgtttctt ctaaggttgg cataaatgga tttcctggtg
    21361 cgcaggcatc aatcaaggca ttcttagaaa ggtattcaaa gtcgaaatct ttttcttcaa
    21421 taccaagttc agtcagtttc ttaggaatac ctactgtctc agaaagcttc tcaatctcaa
    21481 caatcgcata atcggcacat tcttgatctg atttaccttc tacatgaagt cccaaggctt
    21541 tggcaacatt gcggaaagct tctggtacac gtttagcatt ttcatgttct ataactggta
    21601 gcaacatggc acagcaaaca ccatgtggca aattatatac tgcaccgagt tggtgagcca
    21661 ttgagtgaac ataaccaaga ccagcattat taaagctcat accaccaagg aagatggcat
    21721 tgaccatacc ttcacgcgct tcaatatcat gtccattttc tacagcacga ggaagatatt
    21781 ccttgataag ctcaatagca ccaatagaca gtttcttggt tacatcataa gcaccaggtg
    21841 ttaccaaagc ttcaacagcg tgagtcagag catccatacc agtagcagca gtcaaggctt
    21901 gaggtttgga aagcatgagt tcagggtcat tgacagaaat caaggcaagg ctattcttgt
    21961 caaccattac catcttaacc ttgcgttctt catcagtaat cacatagtta atagtgattt
    22021 ctgctgatgt acctgccgtt gtattgatag ccacaaccgg caagcctttt ttagcagact
    22081 tatgaagccc ttcataatcc tgtggttttc caccatttgt agccatgata gaaatacaac
    22141 tagctgcatc ctgtggagaa cccccgccaa gactgatgat aaaatcacat ctatgttctt
    22201 gcaaagcagc taccccatct gtgacatttt tacaagtagg gtttggctct acatcgctaa
    22261 agatgacata ttcgattcct tctgtatcca gtggttttaa agtcttaggt aaaatatcac
    22321 tgccttcgat gtacttatct gtcaccaaaa gtgccttttt atagccaagt tccttgatat
    22381 aaggacccac ttcatttaca acaccttttc caataaggtt gactgccgga acataaaata
    22441 tagccatata attttcctcc tgcgcctccg cgctatctat ttaacatcat tatattactt
    22501 tttgtattcg ttttcaatta tttgtgaatt gtttaacaaa tctttttaaa aggataggag
    22561 ggacgtaagt tcacctccta tataaacaag ttttatttat gtagtggtcc caacaactga
    22621 catgcacgat agtctgctga ttctagatct tctgttccaa ataaggacca atttttaggt
    22681 ctaaagatat cttcctcagg tacattatgc atattgacag gaattctcaa catagaagcc
    22741 aaggtaatca agtctgctcc aatgtgtcca tatgttatgg ctccgtgatt agctccccaa
    22801 ttattcatga cgtcatagac agacttgaaa gcaccttttc ctgtcaaacg tggagcaaac
    22861 caagtagttg gccatcctga atctgtacga ttatctaaag tatggtgaac atcttcagga
    22921 agttcaagtg tgtaaccttc tgcaatttgt agcactggac caaccccttt tagaagattg
    22981 agacgtacca ttgttactgg catatccccc ttcgtcaaga aacgagttga gaatcctcct
    23041 ccacggaagt actcgcggtt tgctggtggg aagtctgtat tttcaagcat agcctgtact
    23101 tcactttctt ccaactccca gaatggtttc ataacaggtt tgccatctcg agtagcttga
    23161 cctgtaccat ccaatgtaca agaaccagag ttgattagat gtaagaagcc agctgcagca
    23221 caaccctcta aagtatgtcc cgttacacgt ttaacagcct ctggactcca ataagtgcgc
    23281 acatcagcaa agatttgtgg agtatttgtt aatagataat taaagagcat agacacacca
    23341 tttagtgaat cattctctgt cgcaaataca aatggttttc gaataccatt ccagtcaaac
    23401 tgagtattga ggaaagtttc cataaaatct ccatttggaa aatggtctgt ccactgacgt
    23461 tgaccttgga aaccagctac taaagcatgg tgaccaaccg cttcttcctc aaaaccaagt
    23521 tcagcaagcc ttgggttacc aaccattaag tcacgtccaa tcatgaacat cttaataaca
    23581 aattcccatt gtttttcttt ctcttcttta gaaagaatca aatcctcacg atttcggtca
    23641 accccttctt tgatatgttc ttttacccaa accatagcac gttcgaactc ttctgggtca
    23701 taaataccac ggtccatacg gcgcgtgaac tccgtcatat ctaccgattc atttcgcatt
    23761 cctaagtatt cttggaagaa atctggattt acaatagaac cgccaatccc catcgaaaca
    23821 ctacccattg ataggtaagc agtgtctctc atcaagccag ttgcaagagc tgcacgcgca
    23881 taacgtaaaa gtttttcttt gacatcttct ggaatatctg tatcattagc ttcctgaaca
    23941 tctctaccat aaatcccaaa ggctggaatc cctttttgag catgtgaagc tagtacagct
    24001 gcaagataga cagctcctgg gcgttctgtc ccattaaatc cccaaatagc atgaggaata
    24061 tctggagaca tatccatagt ttcactacca taacaccagc atggtgtaac tgtaattgtt
    24121 gcgcaaacat ttgatttttt aaacaactca tgggaagctg cagcctctgg aacacgacca
    24181 atggtagatg gagaaatcac acattccaca ggttccccat ctggatattt caatgtgctt
    24241 gaaatcaaat ctgccacact tttagccatg ttcattgttt gtacttcaag tgattcgcgt
    24301 acaccttgac gacgaccatc aatagtcgga cgaatcccaa tacgtggatg ttgaatcata
    24361 ctattttcct cttatttttc tgtttctttc atactaccga tgataatttt taaaattact
    24421 tataagtata aacctctacc tctgccaaac ttaaaggaat tcctgcgttt ctcaaagaaa
    24481 ttctaacctt ttttcccttc agccctttta agtctatgga tagattattg ctttctaaac
    24541 tgtcaatatg ttgtttaaaa acttcatgat tatttgaatc atatataata atatcaaaat
    24601 ttgataatct ctgaatttca gcatctgttc tattataaat aattaacttt tctaattctt
    24661 cggtttgtgc taaatctatc tcccaccatg aaggagaatc tcctttggta tgagtcactg
    24721 aatgatgacc ataatctccg tttttatttc catcaactgc tagacgagaa aaaccattgt
    24781 aatccgttga actctgtcga gtttctttgg ttaatgcaat attagaaagt ttcttcggag
    24841 ttctctttga accataggct tcaacttccg ctaaacttaa cggaatagct gctgatttta
    24901 attctatttt gactagctta gcccctacag aaggtacttt taaagataac aaaccatcaa
    24961 ctactttatc aaaatgtctt ctaaaaactt cttctcctga tgaagataga aaaataacat
    25021 caaaattaga taaacgctga ggttcggcat ctgttctatt ataaatatca actttagaaa
    25081 ccgtaaactc ttctcccaga tcgacctgcc accaagcgtt agaatctgcc ttagtatgag
    25141 tcaccgaatg atgtccgtaa tctccatctt tattaccatc aactgctaaa gcagctacac
    25201 cctcataatt ggttgaactt tgagtagcta ccttatttgt agagactact ttatcttctg
    25261 ttattttatc tatatcctct tcagattgct taccatctga ttctctaaaa acctctactt
    25321 ctgctaaact caaaggcact ccactcgtta gtaatttaac tttaatatac cttgctcctt
    25381 tttctttgaa atctagacta acagattcac ccgacaaatt attaacatgt ttcttagcaa
    25441 cttcgtttct attattgtca tatagaatca catcaaaatt agatagacgt tgagtctcag
    25501 catctgtgcg attataaatt ttaacaagcc caactttatc catttttttc aaatcgactt
    25561 cccaccaaga gggattatct gccctagtgt gtgttaccga accagagtta aaattaccat
    25621 ttctgttacc atccacagct ctattagggt ctccattgta atctacagaa ctttgtgttg
    25681 ttggttttgc atatgctata ttcaaattac catcattaaa tttatctggt gttgggaaag
    25741 ggactgggcc tgtcccttca gtatttatag acatctctac cattccatta tgattaaccg
    25801 taatggtata aacatgggta ttctcatccc aattttctgt ataagtataa tgatttttat
    25861 cgccacttat atttatctga ggtttatgac cagtatgccc ttttaatgta agtgttgttg
    25921 tcctaaagtc attatctaca ggattgatgg aataattttt gcttatccag ttcgctaact
    25981 ctaattcttc tttcttccaa ctttttgatg catcaaaatt tcctgataat gcccacatag
    26041 ctgtcttatc tgtcctgtaa tt
//
LOCUS       DAVBBO010000028        25336 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ST1
            SAMEA2066453-rid20184263.denovo.028, whole genome shotgun sequence.
ACCESSION   DAVBBO010000028 DAVBBO010000000
VERSION     DAVBBO010000028.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2066453
            Sequence Read Archive: ERR351777
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 25336)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 25336)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980402.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980402.1
            Genome Coverage       :: 176x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:17:33
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,141
            CDSs (total)                      :: 2,104
            Genes (coding)                    :: 1,953
            CDSs (with protein)               :: 1,953
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 16S)
            partial rRNAs                     :: 1 (23S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 151
            CDSs (without protein)            :: 151
            Pseudo Genes (ambiguous residues) :: 0 of 151
            Pseudo Genes (frameshifted)       :: 73 of 151
            Pseudo Genes (incomplete)         :: 76 of 151
            Pseudo Genes (internal stop)      :: 40 of 151
            Pseudo Genes (multiple problems)  :: 32 of 151
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..25336
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2066453-rid20184263.denovo.028"
                     /strain="ST1"
                     /db_xref="taxon:1313"
     gene            complement(<1..309)
                     /locus_tag="VQU30_001148"
     CDS             complement(<1..309)
                     /locus_tag="VQU30_001148"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466308.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron ABC transporter substrate-binding protein"
                     /protein_id="HET2447264.1"
                     /translation="MKKKWMYYAACSSNESADDSSSDKGDGGSLVVYSPNSEGLIGAT
                     IPAFEEKYGIKIELIQAGTGELFKKLESEKEVPVADIIFGGSYTQYATHGELFENYIS
                     K"
     gene            complement(897..1673)
                     /locus_tag="VQU30_001149"
     CDS             complement(897..1673)
                     /locus_tag="VQU30_001149"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000406168.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycyl-radical enzyme activating protein"
                     /protein_id="HET2447265.1"
                     /translation="MEISKGIIFNIQHFSIHDGPGIRTTVFLKGCPLRCPWCSNPESQ
                     RMKPEKMKDAQREKFTLVGEEKTVEEIITEVLKDKEFYEESGGGLTLSGGEIFAQFEF
                     AKAILKSAKEHHIHTAIETTAFVDHEKFIDLIQYVDFIYTDLKHYNSIKHKKVTGVFN
                     QMIIKNIHYAFSQNKTIVLRIPVIPNFNNSLEDAEKFATLFNSLNIDQVQLLPFHQFG
                     ENKYRLLNRKYEMDGINALHPEDLIDYQKVFLNHHINCYF"
     gene            1795..2541
                     /locus_tag="VQU30_001150"
     CDS             1795..2541
                     /locus_tag="VQU30_001150"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000824973.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HET2447266.1"
                     /translation="MKRLEQIIKLVSEYEKIDVNTLSEKLNVSKVTIRKDLDKLESKG
                     LLHREHGYAVLNSGDDLNVRLSINYEIKRKIVQEAVKLVSDNETIMIESGSTCALLAE
                     EICKQKRNVTIVTNSFFIANFVRAYDSCRIIVLGGEFQKDSQVTVGPLLKEMIQTFHV
                     HQAFVGTDGYDKEMGFTGKDLMRSEVVQYISAASDKVIVLTDSSKFDKRGTVRRFALS
                     QVYEVITDEKLSKQNIATLENAGIMVKVVS"
     gene            2554..3534
                     /locus_tag="VQU30_001151"
     CDS             2554..3534
                     /locus_tag="VQU30_001151"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001070834.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar-binding transcriptional regulator"
                     /protein_id="HET2447267.1"
                     /translation="MNQDRNKLLSKIAYLYYIENLNQSQIAAKLGIYRTSISRMLTEA
                     RNAGIVKIEIENFDTNMFKLENYVKEKYGLESLEIIPNEFDDNPTILSERISQVAAGV
                     LRNLIDDNMKIGFSWGKSLSNLVDLIHSKSVRNVHFYPLAGGPSHIHAKYHVNTLIYE
                     MSRKFHGECTFMNATIVQENKLLADGILQSRYFENLKNSWKDLDIAVVGIGDFSNKGK
                     HQWLDMLTEDDFKELTKVKTVGEICCRFFDSKGKEVYENLQERTIAISLEDLKNIPQS
                     LAVAYGDTKVSSILSVLRANLVNHLITDKNTILKVLEEDGDLTFREILGE"
     gene            3729..4049
                     /locus_tag="VQU30_001152"
     CDS             3729..4049
                     /locus_tag="VQU30_001152"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000402908.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HET2447268.1"
                     /translation="MEIIVPDQIIMGLILYAGDAKQHIYKALDYIKNGTCERCEEEIQ
                     LADAALLEAHNLQTKFLAQEASGTKTEITALFVHSQDHLMTSMTEINLIKEIISLRKE
                     LHKK"
     gene            4095..4403
                     /locus_tag="VQU30_001153"
     CDS             4095..4403
                     /locus_tag="VQU30_001153"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000238716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HET2447269.1"
                     /translation="MVKIGLFCAAGFSTGMLVNNMKIAAQSSGVEAEIEAFSQSKLAD
                     YAPNIDVALLGPQVAYTLDKSKEICDKCDVPIAVIPMMDYGMLDGKKVLDLALSLISG
                     "
     gene            4420..5718
                     /locus_tag="VQU30_001154"
     CDS             4420..5718
                     /locus_tag="VQU30_001154"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000041357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HET2447270.1"
                     /translation="MSKMDVQKIIAPMMKFVNMRGIIALKDGMLAILPLTVVGSLFLI
                     MGQLPFEGLNKSIASVFGANWTEPFMQVYSGTFAIMGLISCFSIAYSYAKNSGVEALP
                     AGVLSVSAFFILLRSSYIPKQGEAIGDAISKVWFGGQGIIGAIIIGLVVGSIYTFFIK
                     RKIVIKMPEQVPQAIAKQFEAMIPAFVIFLSSMIVYILAKSLTNGGTFIEMIYSAIQV
                     PLQGLTGSLYGAIGIAFFISFLWWFGVHGQSVVNGVVTALLLSNLDANKAMLASANLS
                     LENGAHIVTQQFLDSFLILSGSGITFGLVVAMLFAAKSKQYQTLGKVAAFPAIFNVNE
                     PVVFGFPIVMNPVMFVPFILVPVLAAVIVYGAIATGFMQPFSGVTLPWSTPAILSGFL
                     VGGWQGVITQLVILAMSTLVYFPFFKVQDRLAYQNEIKQS"
     gene            5869..8307
                     /locus_tag="VQU30_001155"
                     /pseudo
     CDS             5869..8307
                     /locus_tag="VQU30_001155"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000248319.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="glycyl radical protein"
     gene            8326..8994
                     /locus_tag="VQU30_001156"
     CDS             8326..8994
                     /locus_tag="VQU30_001156"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000395441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fructose-6-phosphate aldolase"
                     /protein_id="HET2447271.1"
                     /translation="MEFMLDTLNLDEIKKWSEILPLAGVTSNPTIAKREGSINFFERI
                     KDVRELIGSTPSIHVQVISQDFEGILKDAHEIRRQAGDDIFIKVPVTPAGLRAIKVLK
                     KEGYHITATAIYTVIQGLLAIEVGADYLAPYYNRMENLNIDSNSVIRQLALAIDRQNS
                     PSKILAASFKNVAQVNNALAAGAHAVTAGADVFESAFAMPSIQKAVDDFSDDWFVTQN
                     SRSI"
     gene            9012..10100
                     /locus_tag="VQU30_001157"
     CDS             9012..10100
                     /locus_tag="VQU30_001157"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001860765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol dehydrogenase"
                     /protein_id="HET2447272.1"
                     /translation="MRIFASPSRYIQGENALFENAKSILDLGNYPILLCDQLVYDIVG
                     KRFEDYLHRYGFHIVLALFNGEASDNEINRVVALAEKENCDSIIGLGGGKTIDSAKAI
                     ADLIEKPVIIAPTIASTDAPVSALSVIYTDEGAFDHYLFYSKNPDLVLVDTKVISQAP
                     KRLLASGIADGLATWVEARAVMQANGKTMLGQQQTLAGVAIAKKCEETLFADGLQAMA
                     ACEAKVVTPALENIVEANTLLSGLGFESGGLAAAHAIHNGFTALTGDIHHLTHGEKVA
                     YGTLVQLLLENRPKEELDKYIEFYKKIGMPTTLKEMHLDQVGYDDLIKVGKQATMEGE
                     TIHQMPFKISPSDVAQAIIAVDAYVNSK"
     gene            10555..13056
                     /locus_tag="VQU30_001158"
     CDS             10555..13056
                     /locus_tag="VQU30_001158"
                     /EC_number="6.1.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014639013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="leucine--tRNA ligase"
                     /protein_id="HET2447273.1"
                     /translation="MSFYNHKEIEPKWQGYWAEHHTFKTGTDASKPKFYALDMFPYPS
                     GAGLHVGHPEGYTATDILSRYKRAQGYNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTA
                     ENIANFKRQINALGFSYDWDREVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVE
                     ELGTAIANEEVLPDGTSERGGYPVVRKPMRQWMLKITAYAERLLNDLDELDWSESIKD
                     MQRNWIGKSTGANVTFKVKGTDKEFTVFTTRPDTLFGATFTVLAPEHELVDAITSTEQ
                     AEAVADYKHQASLKSDLARTDLAKEKTGVWTGAYAINPVNGKEIPIWIADYVLASYGT
                     GAVMAVPAHDQRDWEFAKQFDLPIVEVLEGGNVEEAAYTEDGLHVNSDFLDGLNKEDA
                     IAKIVAWLEEKGCGQEKVTYRLRDWLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLV
                     LPVTKDIRPSGTGESPLANLTDWLEVTREDGVKGRRETNTMPQWAGSSWYYLRYIDPH
                     NTEKLADEDLLKQWLPVDIYVGGAEHAVLHLLYARFWHKFLYDLGVVPTKEPFQKLFN
                     QGMILGTSYRDHRGALVATDKVEKRDGSFFHVETGEELEQAPAKMSKSLKNVVNPDDV
                     VEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLDRVYRLIRSKEIVAENNGALD
                     KVYNETVKAVTEQIDSLKFNTAIAQLMVFVNAANKEDKLYVDYAKGFIQLIAPFAPHL
                     AEELWQTVAATGESISYVTWPTWDESKLVEDEIEIVVQIKGKVRAKLMVAKDLSREEL
                     QEIALADEKVKAEIDGKEIVKVISVPNKLVNIVVK"
     gene            13250..13945
                     /locus_tag="VQU30_001159"
     CDS             13250..13945
                     /locus_tag="VQU30_001159"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001144916.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HET2447274.1"
                     /translation="MPVNEYGQMIGESMEGYTPGELPSIDFLEGRYARIEALSVEKHA
                     EDLLAVYGPDTPQEMWTYLFQEPVADMGELVSLLHQMLARKDRFYYAIIDKATGKALG
                     SFSLMRIDQNNRVIEVGAVTFSPELRGTRIGTEAQYLLARYVFEELNYRRYEWKCDAL
                     NLPSRRAAERLSFIYEGTFRQAVVYKGRTRDTDWLSMIDKDWPQVKDRLETWLRPENF
                     DKNGQQYKSLREL"
     gene            13957..14373
                     /locus_tag="VQU30_001160"
     CDS             13957..14373
                     /locus_tag="VQU30_001160"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862593.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HET2447275.1"
                     /translation="MITIKKQEIVKLEDVLHLYQAVGWTNYTHQPEMLEQALSHSLVI
                     YLALDGDAVVGLIRLVGDGFSSVLVQDLIVLPIYQRQGIGSALMKEALEDYKDAYQVQ
                     LVTEETERTLGFYRSMGFEILSTYNCIGMTWMNRKK"
     gene            complement(15000..15092)
                     /locus_tag="VQU30_001161"
     CDS             complement(15000..15092)
                     /locus_tag="VQU30_001161"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I toxin-antitoxin system Fst family toxin"
                     /protein_id="HET2447276.1"
                     /translation="MMELVLKTIIGPIVVGVVLRIVDKWLNKDK"
     gene            15253..16224
                     /gene="ruvB"
                     /locus_tag="VQU30_001162"
     CDS             15253..16224
                     /gene="ruvB"
                     /locus_tag="VQU30_001162"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000502070.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction branch migration DNA helicase
                     RuvB"
                     /protein_id="HET2447277.1"
                     /translation="MGDEELVERTLRPQYLREYIGQDKVKDQLQIFIEAAKMRDEALD
                     HVLLFGPPGLGKTTMAFVIANELGVNLKQTSGPVIEKAGDLVAILNELEPGDVLFIDE
                     IHRLPMSVEEVLYSAMEDFYIDIMIGAGEGSRSVHLELPPFTLIGATTRAGMLSNPLR
                     ARFGITGHMEYYAHADLTEIVERTADIFEMEITHEAASELALRSRGTPRIANRLLKRV
                     RDFAQIMGNGVIDDIITDKALTMLDVDHEGLDYVDQKILRTMIEMYSGGPVGLGTLSV
                     NIAEERETVEDMYEPYLIQKGFIMRTRSGRVATAKAYEHLGYEYSEK"
     gene            16205..16777
                     /locus_tag="VQU30_001163"
     CDS             16205..16777
                     /locus_tag="VQU30_001163"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001098890.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyltransferase family protein"
                     /protein_id="HET2447278.1"
                     /translation="MNTVKNKQEILEAFRENPDMMAILTIIRDLGLKDSWLAAGSVRN
                     FIWNLLSDKSPFDHETDIDVIFFDPDFSYEETLLLEKKLREDFPQYQWELKNQVYMHQ
                     HSPHTASYTSSRDAMSKYPERCTAVGLRLNEESDFELYAPYGLEDILNFQVRPTPHFL
                     ENEDRMELYQTRLSKKNWQEKWKNLIFKNT"
     gene            17008..17766
                     /locus_tag="VQU30_001164"
     CDS             17008..17766
                     /locus_tag="VQU30_001164"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000466694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isoprenyl transferase"
                     /protein_id="HET2447279.1"
                     /translation="MFGFFKKDKAVEVEVPTQVPAHIGIIMDGNGRWAKKRMQPRVFG
                     HKAGMEALQTVTKAANKLGVKVITVYAFSTENWTRPDQEVKFIMNLPVEFYDNYVPEL
                     HANNVKIQMIGETDRLPKQTFEALTKAEELTKNNTGLILNFALNYGGRAEITQALKLI
                     SQDVLDAKINPGDITEELIGNYLFTQHLPKDLRDPDLIIRTSGELRLSNFLPWQGAYS
                     ELYFTDTLWPDFDEAALQEAILAYNRRHRRFGGV"
     gene            17775..18578
                     /locus_tag="VQU30_001165"
     CDS             17775..18578
                     /locus_tag="VQU30_001165"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000189872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatidate cytidylyltransferase"
                     /protein_id="HET2447280.1"
                     /translation="MTQDLQKRTLFAGIALAIFLPILMIGGLLLQIAIGIIAMLAMHE
                     LLKMRGLETMTMEGLLTLFATFALTIPLENYLTFLPVDGNVVAYSVLISIMLGTTVFS
                     KSYTIEDAVFPLAMSFYVGFGFNALLDARVAGLDKALLALCIVWATDSGAYLVGMNYG
                     KRKLAPRVSPNKTLEGALGGILGAILVTIIFMIVDSTVALPYGIYKMSVFAIFFSIAG
                     QFGDLLESSIKRHFGVKDSGKFIPGHGGVLDRFDSMLLVFPIMHLFGLF"
     gene            18600..19859
                     /gene="rseP"
                     /locus_tag="VQU30_001166"
     CDS             18600..19859
                     /gene="rseP"
                     /locus_tag="VQU30_001166"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000900658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RIP metalloprotease RseP"
                     /protein_id="HET2447281.1"
                     /translation="MLGILTFILVFGIIVVVHEFGHFYFAKKSGILVREFAIGMGPKI
                     FAHIGKDGTAYTIRILPLGGYVRMAGWGDDTTEIKTGTPVSLTLADDGKVKRINLSGK
                     KLDQTALPMQVTQFDFEDKLFIKGLVLEEEKTFAVDHDATVVEADGTEVRIAPLDVQY
                     QNATIWGKLITNFAGPMNNFILGVVVFWVLIFMQGGVRDVDTNQFHIMPQGALAKVGV
                     PETAQITKIGSHEVSNWESLIQAVETETKDKTAPTLDVTISEKGSDKQVTVTPEDSQG
                     RYLLGVQPGVKSDFLSMFVGGFTTAADSALRILSALKNLIFQPDLNKLGGPVAIFKAS
                     SDAAKNGIENILYFLAMISINIGIFNLIPIPALDGGKIVLNILEAIRRKPLKQEIETY
                     VTLAGVVIMVVLMIAVTWNDIMRLFFR"
     gene            19872..21725
                     /locus_tag="VQU30_001167"
     CDS             19872..21725
                     /locus_tag="VQU30_001167"
                     /EC_number="6.1.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000814078.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="proline--tRNA ligase"
                     /protein_id="HET2447282.1"
                     /translation="MKQSKMPIPTLREMPSDAQVISHALMLRAGYVRQVSAGVYSYLP
                     LANRVIEKAKNIMRQEFEKIGAVEMLAPALLSAELWRESGRYETYGEDLYKLKNREKS
                     DFILGPTHEETFTAIVRDSVKSYKQLPLNLYQIQPKYRDEKRPRNGLLRTREFIMKDA
                     YSFHANYDSLDSVYDEYKAAYERIFTRSGLDFKAIIGDGGAMGGKDSQEFMAITSART
                     DLDRWVVLDKSVASFDEIPAEVQEEIKAELLKWIVSGEDTIAYSSESSYAANLEMATN
                     EYKPSNRVVAEEEVTRVATPDVKSIDEVAAFLNVPEEQTIKTLFYIADGELVAALLVG
                     NDQLNEVKLKNHLGADFFDVASEEEVANVVQAGFGSLGPVGLPENIKIIADRKVQDVR
                     NAVVGANEDGYHLTGVNPGRDFTAEYVDIREVREGEISPDGQGVLNFARGIEIGHIFK
                     LGTRYSASMGADVLDENGRAVPIIMGCYGIGVSRLLSAVMEQHARLFVNKTPKGEYRY
                     AWGINFPKELAPFDVHLITVNVKDEEAQALTEKLEASLMGAGYEVLTDDRNERVGVKF
                     SDSDLIGLPIRITVGKKAADGIVEVKIKATGDTIEVHADNVLETLEILSKK"
     gene            21825..23204
                     /gene="bglA"
                     /locus_tag="VQU30_001168"
     CDS             21825..23204
                     /gene="bglA"
                     /locus_tag="VQU30_001168"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000943526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-glucosidase"
                     /protein_id="HET2447283.1"
                     /translation="MLRFPKDFVWGSSTSGPQTEGRVAGDGKGDNLWDYWFQVEPNRY
                     YNGIGSDKTSTFYENWERDIELLLETGHTVFRTSIQWSRIFPQGCGKVNPQGVDFYRK
                     VFEAIKAKGIRLLVNLYHFDLPFALQEDGDGWENKATVSAYEDYARFCFETYGDLVDQ
                     WITFNELIVPVEFGYFYDAHYPHKVDAEAAVKVAYHTQLASSRAVKACHELLPDSKIG
                     IVLNLTPAYPRSQHPADVKAARIAALFQAQSFLDPSVLGTYPQELVEILHEHGLLPDA
                     TEEELELIHDNTVDFLGVNYYQPLRVMAPRFAKHPESPLLPEHFYEPYVMPGRKINSH
                     RGWEIYEQGIYDIAQNIKENYGNIEWMLTENGMGVEGEEKFRQDGMIQDDYRIDFVKG
                     HLRELHRAIEDGANCKGYLIWTFIDCWSWLNSYKNRYGLVELDLETQERRLKKSGHWF
                     KKLSDNNGF"
     gene            23396..25204
                     /gene="glmS"
                     /locus_tag="VQU30_001169"
     CDS             23396..25204
                     /gene="glmS"
                     /locus_tag="VQU30_001169"
                     /EC_number="2.6.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014621492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine--fructose-6-phosphate transaminase
                     (isomerizing)"
                     /protein_id="HET2447284.1"
                     /translation="MCGIVGVVGNTNATDILIQGLEKLEYRGYDSAGIFVLDGADNHL
                     VKAVGRIAELSAKTAGVEGTTGIGHTRWATHGKPTEDNAHPHRSETERFVLVHNGVIE
                     NYLEIKEEYLAGHHFKGQTDTEIAVHLIGKFAEEDGLSVLEAFKKALHIIRGSYAFAL
                     IDSENPDVIYVAKNKSPLLIGLGEGYNMVCSDAMAMIRETNQYMEIHDQELVIVKADS
                     VEVQDYDGNRRERASYTAELDLSDIGKGTYPYYMLKEIDEQPTVMRKLIQAYTDEAGQ
                     VVVDPDIIKAVQDADRIYILAAGTSYHAGFASKKMLEELTDTPVELGISSEWGYGMPL
                     LSKKPLFIFISQSGETADSRQVLVKANEMGIPSLTVTNVPGSTLSREANYTMLLHAGP
                     EIAVASTKAYTAQIAALAFLAKAVGEANGNAKAQAFDLVHELSIVAQSIESTLSEKET
                     IEAKVRELLETTRNAFYIGRGQDYYVAMEASLKLKEISYIQCEGFAAGELKHGTIALI
                     EEGTPVLALLSDPVLANHTRGNIQEVAARGAKVLTIAEENVAKDTDDIVLTTVHPYLS
                     PISMVVPTQLVAYFATLHRGLDVDKPRNLAKSVTVE"
BASE COUNT         7736 a         4312 c         5536 g         7752 t
ORIGIN      
        1 ttttgaaata tagttttcaa agagttctcc gtgggtagca tattgtgtat aagaaccacc
       61 aaagataata tcagctacag gaacttcttt ttctgactct agttttttga aaagttctcc
      121 agtaccagct tgaatcagtt ctattttgat accatatttt tcttcaaagg caggaatagt
      181 tgctccaatt aagccttctg agtttggtga ataaacgact agcgaaccac cgtctccttt
      241 atcagatgaa ctgtcatcgg cagattcatt agaagaacaa gcagcataat acatccattt
      301 ctttttcatg atggatacct ccgttgtgtt atttaagttt attttaaaac aatgtaagcg
      361 tttttaaaac ctacaattct attctatagt gtattgaatc tataacagta cacattgact
      421 gctaaaatat ttctataaat taatttgact ttcctgatag agatgttcac atcttatttc
      481 aattcactat attagagtaa aattctctac aaaaaaaaag aatagcctat tttactattt
      541 ttccgagtga tttcaattcc tttggggaaa tatggagata ctttttaaat cctgacaaat
      601 ggttgtttct ttttctaaat cggtgatact gtatcggaga atgcgcgtga ggtcacaaag
      661 gctgcgatag agcttctatg gagaatttct ttttggagag attttttaaa ggaatgagac
      721 atccgctacc tccttggaag gtttttttgt gataagtata gcagtttaaa aattctagag
      781 caaggtaaaa tagaaaaggt ttggctaaaa ttttttagct aaaccttttg aaaagttaag
      841 tatgtattat agatgcttgt tatctgcaaa tagctagagc atttcaagga aataaactag
      901 aaataacaat taatatggtg gttcagaaat accttttgat aatcaataag atcttcagga
      961 tgaagtgcgt tgattccatc catttcatat ttccgattta ataaacgata tttgttttca
     1021 ccaaattgat gaaaagggag tagttgaact tggtcgatat ttaatgagtt aaatagagta
     1081 gcgaattttt ctgcatcctc taaactattg ttaaaattag gaataactgg gattcttaaa
     1141 acgatagttt tattttgtga aaaagcataa tgaatgtttt taataatcat ttgattaaaa
     1201 accccagtca cttttttatg ttttatagaa ttataatgtt ttaggtctgt gtagataaaa
     1261 tccacatatt gaattaaatc aataaatttt tcatgatcaa caaaggcagt agtttcaatg
     1321 gcagtgtgta tgtgatgttc tttagctgat tttaagatag ctttagcaaa ttcaaactga
     1381 gcaaatattt cacctcctga taaagttaaa cctccaccgg attcttcgta aaattctttg
     1441 tcttttaata cctctgtaat aatttcttct acagtctttt cttcaccgac taaggtgaat
     1501 ttctctcgtt gagcatcttt cattttttca ggtttcattc tttgagattc aggattagaa
     1561 caccatggac agcgcagagg acatcctttt aaaaaaacag ttgtacgaat acccgggccg
     1621 tcatgaattg aaaagtgttg aatattaaaa ataattcctt tagatatttc cataagagtt
     1681 cctcctcttc ataagtctat cctatcacaa aaacgaaaga aaaacaatta cgaacgaaag
     1741 gttaatttgt tgttttttgc tttttatttt ggtagaataa aacggaggtg taaaatgaaa
     1801 agattggaac aaattattaa attagtatca gaatatgaaa agatcgacgt taatacatta
     1861 tcggaaaaat taaatgtatc gaaagtaacg attagaaaag atttagataa attagagtca
     1921 aaaggtttat tacacagaga gcatggatat gctgtattaa atagtggaga tgacttaaat
     1981 gtacgtttgt caattaatta tgaaattaag agaaaaattg ttcaggaagc agtaaaattg
     2041 gtgtcagata atgaaacgat aatgatagaa tctggatcga cctgtgcttt acttgctgag
     2101 gaaatttgca agcaaaaaag aaatgttacg attgtaacaa attcattttt tatagcaaat
     2161 tttgtgagag cttatgattc atgtcgtatt attgttcttg gtggagagtt tcagaaggat
     2221 tcacaggtta ctgtgggacc tttattaaaa gaaatgatac agacttttca tgtgcatcaa
     2281 gcttttgttg ggacagatgg atacgataaa gagatgggct ttacaggaaa agatttaatg
     2341 cgcagtgagg tagttcaata tatttcagca gcgtcggata aagtcattgt cctaactgac
     2401 tcaagtaaat ttgataaaag gggtacagta agaagatttg ctttaagtca agtctatgaa
     2461 gtaataacag acgaaaaact ttctaaacaa aatatagcta cattagaaaa tgctgggata
     2521 atggttaagg tagtttcgta agaggttaag tgtatgaatc aagataggaa taaactgctc
     2581 tctaaaattg cttatctgta ttatattgaa aacttaaatc agtcacaaat agcagcaaaa
     2641 ttaggaattt atagaacctc tattagtaga atgttaacag aagcaaggaa tgcaggaatt
     2701 gttaaaattg aaatagagaa ttttgatacc aatatgttta agttggaaaa ttatgtaaaa
     2761 gaaaaatatg gtctggaaag tttagaaatt attccaaatg aatttgatga taatccaaca
     2821 attttatctg aaagaatttc tcaagttgca gcaggtgtcc ttaggaatct aattgatgat
     2881 aatatgaaaa ttggcttttc ttgggggaaa agtttaagta atttagtaga tttaattcac
     2941 agtaaaagtg tccgaaatgt tcacttctat cctctagcag gtggtcctag tcacatacac
     3001 gctaaatacc atgtgaatac actgatttat gaaatgtcta gaaaatttca tggagagtgt
     3061 acatttatga atgcaacgat tgtgcaagaa aataaattgt tagcagatgg tattttgcaa
     3121 tcaagatatt ttgaaaattt gaaaaatagt tggaaagatt tagatatagc tgtagtcgga
     3181 attggtgatt ttagcaataa aggaaagcat caatggttag acatgcttac agaggatgac
     3241 tttaaagaat tgaccaaagt taaaactgta ggagaaattt gttgtcgatt ttttgattca
     3301 aaaggtaaag aagtctatga aaacttacag gaaagaacga tagcaatctc tttggaagat
     3361 ttaaaaaata ttcctcaaag tttagctgtt gcttacggtg atacgaaagt atcttcgatt
     3421 ctttctgtct tgcgtgctaa tttagtaaat catttgatta cagacaaaaa tacaatttta
     3481 aaagttttgg aagaagatgg ggatttgact tttagagaga ttctaggtga gtgaaaatga
     3541 tagactgatt cagtttatcg tttttctttt tagttgattg cacatttgtg cttatataaa
     3601 caaaaatagt ttatctgttg tttttggatt gacaacttta ttatgtagtt gtattctata
     3661 gttacaaaag aaaattttaa aatttcaaat gaaaaaagct ttttacatag tgaaatgagg
     3721 aggaatttat ggaaattatt gttccagatc aaattatcat gggtttaatt ttatatgctg
     3781 gtgatgcgaa acaacatatt tataaagcgt tagattacat aaaaaatggt acatgtgaac
     3841 ggtgtgaaga agaaatccag ttagctgatg ccgccttatt agaagcccat aatctacaaa
     3901 caaaattctt ggcacaagaa gcgtctggta caaagacaga aattacagct ctctttgttc
     3961 attcacaaga tcatctcatg actagtatga cggagattaa tttaatcaaa gaaattatta
     4021 gtttgagaaa agaacttcat aaaaaataat actagagtat tatcattgtt attaacatag
     4081 aggaggaaaa cataatggtg aagattggtt tgttttgtgc agcaggtttt tctactggta
     4141 tgcttgtaaa taatatgaaa attgcagcgc aatctagtgg agttgaggca gaaatagagg
     4201 cgttttctca gtctaaatta gcggattatg cgccaaatat agatgttgca ctattgggtc
     4261 cacaagttgc ttatacatta gataaatcaa aagaaatttg tgataagtgt gatgttccga
     4321 tagctgttat tccgatgatg gactatggta tgttagatgg gaaaaaagta ttagatttgg
     4381 ccctatcttt gattagtggg taagaaaagg agatttatta tgtcaaagat ggatgttcag
     4441 aaaatcattg caccgatgat gaagtttgtg aatatgcgtg gcattatagc tctaaaagat
     4501 gggatgttag caattttgcc attgacagta gttggtagtt tgttcttgat tatgggacaa
     4561 ttgccgttcg aaggattaaa taagagcatt gctagtgttt ttggagctaa ttggacagag
     4621 ccgtttatgc aagtatattc aggaactttt gctattatgg gtctaatttc ttgtttttca
     4681 attgcctatt cttatgctaa gaatagcgga gtagaggctt taccagctgg agttctatct
     4741 gtatctgcat tctttatttt gctaagatca tcttatatcc ctaaacaagg tgaggcgatt
     4801 ggggacgcta ttagtaaagt ttggtttgga ggccaaggaa ttatcggtgc tatcattata
     4861 ggtttggtag taggaagtat ttataccttc tttataaaga gaaaaattgt tattaagatg
     4921 ccagaacaag ttccacaagc tattgccaaa cagtttgaag caatgattcc agcatttgta
     4981 attttcttat cttctatgat tgtatatatt ttagcgaagt cattgactaa tggcggaaca
     5041 ttcatagaaa tgatttattc tgctattcaa gttccgttgc aaggtttaac tggatctttg
     5101 tatggtgcta ttggaattgc attctttata tcatttttgt ggtggtttgg tgttcatggg
     5161 caatcggtag taaatggagt agtgacagct ctgcttttat ctaatcttga cgctaataaa
     5221 gctatgttag cctctgctaa tctatcatta gaaaatggtg cacatattgt tactcaacaa
     5281 tttttagatt catttttaat tctatcaggt tcagggatta cgtttggtct tgtagttgcc
     5341 atgctttttg cagcaaaatc aaaacaatac caaaccttag gaaaagttgc agcttttcca
     5401 gcaatattta acgtaaatga gccagttgta tttggatttc cgattgtcat gaatccagtt
     5461 atgtttgtac ctttcattct tgttcctgta cttgcagctg tgatagtata tggagctatt
     5521 gcaacaggtt tcatgcagcc attctcaggg gtaacattgc cttggagtac accagctatt
     5581 ttatcaggat ttttggtggg tggatggcaa ggagttatta ctcagctggt gatattagcg
     5641 atgtctacat tggtttattt tccattcttt aaagtacagg atcgtttagc ttaccaaaat
     5701 gaaatcaaac aatcttagag gtatttgtgt gttactgtta aactcacaca tttgtgctaa
     5761 aaattagaga gttaaaattt ttctagttaa aagcttgaaa atttctataa aaatcggtat
     5821 tatattttcg aaagaaataa aaatattttc gaaagaaagg tggttacgat ggtaaataca
     5881 gaagtagcaa gaacaacaat caagacagaa tattttggca gccttactga aaggatgaac
     5941 aaatatcgag aagatgtttt aaataaaaaa ccttatattg atgctgagag agcagttcta
     6001 gcaacacgcg cctatgaacg atacaaggaa caacctaatg tcctaaaacg tgcatatatg
     6061 ctgaaagaaa ttttggaaaa tatgactatc tatattgaag aagaatctat gattgcggga
     6121 aatcaagctt cttccaataa agatgctcct atttttccgg aatatacgct agaatttgtt
     6181 ctcaatgagt tggatctttt tgaaaagcgt gatggagatg ttttctatat tacagaagaa
     6241 acaaaagaac aacttagaag tattgctccg ttttgggaaa ataataattt acgtgctaga
     6301 gctggtgcct tattacctga agaagtgtct gtttatatgg aaacaggatt cttcggtatg
     6361 gaaggtaaga tgaattctgg agatgctcac ctagcagtta actatcagaa acttttgcaa
     6421 tttggtttaa gaggttttga agagcgggct cgtaaagcaa aagtagctct agatttaaca
     6481 gatccagcaa gtattgataa atatcatttt tacgactcta tatttatcgt aatcgatgct
     6541 attaaagtat atgcaaagcg ctttgttgct cttgctaaaa gtttagccga aaatgcaaat
     6601 cctaaacgta agaaagaatt acttgagatt gcagatattt gctctagagt cccatatgaa
     6661 ccggcaacta cttttgcaga agctattcaa tcagtttggt ttattcaatg tattttacaa
     6721 attgaatcta atggccactc tctttcatat ggccgttttg atcaatatat gtatccatat
     6781 atgaaggctg atttagaaag tggtaaagaa acagaagata gcattgttga acgtctgaca
     6841 aatctttgga ttaagacaat tacaatcaat aaggttcgca gtcaatcaca tacattttct
     6901 tcagcaggaa gtcctttata tcaaaatgtt acaattggtg gacagactcg agataagaag
     6961 gatgctgtta acccattatc ttatttggta ttaaaatcag ttgcacaaac ccatctaccg
     7021 caacctaatc taactgtacg ttaccatgca ggtttagatg ctcgtttcat gaatgagtgt
     7081 attgaagtga tgaaacttgg ttttggtatg cctgcattta ataatgatga gattattatt
     7141 ccttctttta ttgcaaaagg agtattggaa gatgatgctt atgattacag tgccattgga
     7201 tgtgttgaaa cggcagttcc agggaaatgg ggctatcgtt gcacaggtat gagttatatg
     7261 aacttcccta aggttctact tatcacgatg aatgatggaa ttgatccggc ttcgggtaaa
     7321 cggtttgcac caagctttgg tcattttaag gatatgaaga acttttctga attagaaaat
     7381 gcttgggata aaacactaag atatttgaca cgaatgagtg ttattgttga aaattctatt
     7441 gatttatcat tggaacgaga agttcctgat attctatgtt cagcattgac tgatgattgt
     7501 attggtcgtg gaaaacacct taaagaaggt ggagcagtat atgattatat atcaggattg
     7561 caagttggaa ttgcaaattt gtcggattca ttagctgcaa ttaaaaaatt ggtgtttgag
     7621 gaagaacgta taagcccaag tcagctttgg catgcactgg aaacagatta tgccggagaa
     7681 gaaggtaagg tcattcaaga aatgttgatt catgatgcac ctaagtatgg taatgatgat
     7741 gattatgctg acaaattggt tactgctgct tatgacattt atgttgatga aattgctaaa
     7801 tatcctaata cacgttatgg aagagggcct attggaggaa ttcgttattc aggaacatct
     7861 tctatctcag ccaacgtagg gcagggacgt ggaacattag caactccaga tggacgcaac
     7921 gcgggtacac cgttagcaga gggttgttca ccatcacata atatggatca acacggccct
     7981 acatctgttt taaaatctgt ttcaaaatta ccaacagatg aaatcgtagg tggggttctc
     8041 ttaaatcaga aagtaaatcc tcaaacgtta gccaaagaag aagataaatt aaaactaatt
     8101 gctttgttac gaacattctt taatcgttta catgggtacc atatttaata caatgttgtt
     8161 tccagagaga cgttgattga cgctcagaaa catcctgaaa aacacagaga cttaattgtt
     8221 cgtgttgcag gatactctgc attcttcaat gttctttcta aggcaaccca agatgacatt
     8281 ataggacgta ctgagcatac tttgtaaaat aaagaggttc tttttatgga atttatgctt
     8341 gacacattaa atttagatga gattaaaaag tggtctgaaa ttttgccgct agctggggta
     8401 acttcaaatc ccactattgc aaaaagagag ggttctatta atttttttga acgaatcaaa
     8461 gatgtaagag aattgattgg ctctacaccc tctattcatg ttcaggtgat ttctcaagat
     8521 tttgaaggca tcttaaagga tgctcatgaa attcgaagac aagcaggaga tgatatattt
     8581 atcaaagtac ctgttactcc agctggatta cgtgcaataa aggtgctaaa aaaagagggc
     8641 taccatatca ctgcaacagc tatttataca gttattcagg gattattagc tatcgaagta
     8701 ggagcggatt acctagctcc atattataat agaatggaaa atctgaacat tgattcaaat
     8761 tctgtcattc gtcaattagc tcttgctatt gatagacaga actctcctag taagatttta
     8821 gctgcatcct ttaaaaatgt agcacaagta aataatgctt tagctgcagg tgcgcatgct
     8881 gttacagcag gagcagatgt ttttgaatca gctttcgcca tgccatctat ccaaaaggcg
     8941 gttgatgatt tttctgacga ttggtttgtt actcaaaata gtcgttccat ttagatagag
     9001 aggaaataca tatgagaatt tttgctagtc cttctagata tattcagggg gaaaatgcct
     9061 tgtttgaaaa tgccaaatca attttggatt tgggaaatta ccctattcta ttatgcgatc
     9121 agttggttta tgatattgtt ggaaaacgat ttgaagatta tctacatagg tatggtttcc
     9181 atattgttct ggcgctattt aatggtgaag cttctgacaa tgaaatcaat cgagttgttg
     9241 ccttggctga gaaagaaaat tgtgatagta ttatcggtct tggtggggga aagacgattg
     9301 atagcgcaaa agctattgca gatttgattg aaaagcctgt tattattgct ccaacaattg
     9361 catcgaccga cgcacctgta tctgctttat ctgttattta tacagatgaa ggtgcatttg
     9421 atcattatct attttattct aaaaatccag atttagtttt ggttgataca aaagttattt
     9481 cacaagcccc taagcgttta ttagcgtctg gtattgcaga tggtttagca acttgggttg
     9541 aggcgcgtgc ggttatgcag gcaaatggaa aaactatgtt gggacaacag caaacattgg
     9601 ctggagttgc aattgcgaag aaatgtgaag aaacgctgtt tgcagatggt ttacaggcta
     9661 tggcagcttg tgaagctaaa gtggtgacac cagcattaga aaatattgtt gaagctaata
     9721 ctttattgag tggcctaggt tttgaaagtg gaggattagc tgcggcgcat gcaattcata
     9781 atggttttac tgcattgaca ggtgacattc atcatttaac acatggtgaa aaagtagctt
     9841 atggaacttt agtacaacta ttattggaaa atagacctaa agaagaactt gataagtata
     9901 ttgagtttta caaaaaaatt ggtatgccaa caactctaaa agaaatgcat ttggatcaag
     9961 ttggatatga tgatttaata aaagttggta aacaagcaac tatggagggt gagacaattc
    10021 atcagatgcc gtttaagatt tcgccttcag atgttgctca agctattatc gctgtagatg
    10081 cctatgtaaa ttcaaaataa acaataagga ctactgtttt ccaaatggta gtcttttatt
    10141 gatcctcgta ttgaattcta tagcagattg aaataagatg agaacaaatc gattgggaaa
    10201 gtaaaattaa tttctataag tattttagca attgtttcgt actatttcag attcagtcca
    10261 ctatacgttc ttcataaatc aaaaagcgac ataggttgtc ggctatttat tgtgaataca
    10321 ttaattagca ttccagtttt atcttcggtc taaaataagt attttgtgct atacgagata
    10381 agtttcttga cttactcctt gatttactgc ataacaatgg gataaaaagt gggagataga
    10441 gcaattcata gtcatcaaaa ttaatgagat acagtataca gtttttcctt taaacacatt
    10501 tcaaattccc tcaaaaatgg tataatagta acatcacaaa attggagaga gaccatgagt
    10561 ttttacaatc ataaagaaat tgagcctaag tggcagggct actgggcaga acatcataca
    10621 tttaagacag gaacagatgc atcaaaacct aagttttatg cgcttgatat gttcccttat
    10681 ccgtctggag ctggtctgca cgtaggacac ccagaaggtt atactgcaac cgatatcctc
    10741 agtcgttaca aacgtgcgca aggctacaat gtccttcacc caatgggttg ggatgctttt
    10801 ggtttgcctg cagagcaata cgctatggat actggtaatg acccagcaga atttacagcg
    10861 gaaaacattg ccaacttcaa acgtcaaatc aatgcgcttg gattttctta tgactgggat
    10921 cgtgaagtca acacaacaga tccaaactac tacaagtgga ctcaatggat tttcaccaag
    10981 ctttacgaaa aaggcttggc ctatgaagct gaagtgccag taaactgggt tgaggaattg
    11041 ggaactgcca ttgccaatga agaagtgctt cctgacggaa cttctgaacg tggaggctat
    11101 ccagttgtcc gcaaaccaat gcgccaatgg atgctcaaaa tcacggctta cgcagagcgc
    11161 ttgctcaatg acttagatga actagattgg tcagagtcta tcaaggatat gcaacgcaac
    11221 tggattggta aatcaactgg tgccaatgta actttcaaag taaaaggaac agacaaggaa
    11281 tttacagtct ttactactcg tccggacaca cttttcggtg cgactttcac tgttttggct
    11341 cctgaacatg aattagtaga tgccatcaca agcacagagc aagcagaagc agtagcagac
    11401 tacaaacacc aagccagcct taagtcagac ttggctcgta ccgaccttgc caaagaaaaa
    11461 actggtgtat ggactggtgc ttatgccatc aatcctgtca atggtaagga aattccaatc
    11521 tggattgcgg attacgttct tgctagctat ggtacaggtg cggtaatggc tgtgcctgcc
    11581 cacgatcaac gtgactggga atttgccaaa caatttgacc ttccaatcgt cgaagtactt
    11641 gaaggtggaa atgttgaaga agctgcctac acagaagatg gccttcacgt taattcagac
    11701 ttcctagatg gactcaacaa agaagacgct attgccaaga ttgtggcttg gttggaagaa
    11761 aaaggctgtg gacaagagaa ggtaacctac cgtctccgcg actggctctt tagccgtcaa
    11821 cgttactggg gtgagccaat cccaatcatt cattgggaag atggaacttc aacagctgtc
    11881 cctgaaagtg aattgccact tgttttgcct gtaaccaagg atatccgtcc ctcaggtact
    11941 ggtgaaagtc cactagctaa cttgacagac tggcttgaag tgactcgtga agatggtgtc
    12001 aaaggtcgtc gtgaaacaaa tactatgcca caatgggcag gttcaagctg gtactacctc
    12061 cgctatattg acccacacaa tactgagaaa ttggctgacg aggatctgct caaacaatgg
    12121 ttgccagtag atatctacgt gggtggtgcg gaacatgctg tacttcactt gctttacgct
    12181 cgtttctggc ataaattcct ctatgacctc ggtgttgttc caactaagga accattccaa
    12241 aaactcttta accaaggaat gattttggga acaagctatc gtgaccaccg tggggctctt
    12301 gtggcgactg acaaggttga aaaacgtgat ggttctttct tccatgtgga aacaggggaa
    12361 gagttggagc aagcgccagc caagatgtct aaatcgctca agaacgttgt caacccagac
    12421 gatgtggtgg aacaatacgg tgctgatacc cttcgtgtct atgaaatgtt catgggacca
    12481 ctcgatgctt cgattgcttg gtcagaagaa ggtctggaag gaagtcgtaa gttccttgac
    12541 cgtgtttacc gtttgattag aagtaaggaa attgttgcgg aaaacaatgg cgctcttgac
    12601 aaggtttaca acgaaactgt taaagctgtc acagagcaaa ttgattccct caaattcaac
    12661 acagccattg cccaacttat ggtctttgtc aatgcggcta acaaggaaga caagctctat
    12721 gttgactatg ccaaaggatt tatccaattg attgccccat ttgcacctca cttggcagaa
    12781 gaactctggc aaactgttgc tgcaacaggt gagtcaatct cttacgtgac ttggccaaca
    12841 tgggacgaaa gtaaactggt tgaagacgaa atcgaaatcg ttgtccaaat caaaggtaaa
    12901 gtccgtgcca aactcatggt cgctaaagac ctatcacgtg aagaattgca agaaattgct
    12961 ctagcggatg aaaaagtcaa agcagaaatt gacggtaagg aaatcgtgaa agtgattagt
    13021 gtaccaaata aattggttaa tattgttgta aaataaccaa tttatttgct gatttccaac
    13081 ctcaaacagt ttcccaaact gtttgagcca actaaactcg ttaatatcgt tgtgaaataa
    13141 ggtaggaatc cttcagagta gaatctggag gattttttga atcttcttat gaaagtatgg
    13201 tatactatgg gcaactataa agtttgaaaa gtgaaaaaag gagaaagcta tgccagtaaa
    13261 tgaatatggt caaatgattg gggagtcaat ggaaggttat acaccaggtg aactgccttc
    13321 tattgatttc ttagaagggc gttatgctag gatagaggct ctttcagtgg aaaagcatgc
    13381 ggaggatttg ctagctgttt atgggcctga tacgcctcag gagatgtgga cctacctttt
    13441 tcaggagcca gtagcagata tgggggagct ggttagcctt ttacatcaga tgttggctcg
    13501 taaggaccgt ttttactatg caatcataga caaggcgact ggtaaggctt tgggatcttt
    13561 ttctctcatg cgcattgacc agaataaccg agtaatagaa gtcggagcag tcactttttc
    13621 tccagagcta aggggtacac ggataggaac tgaagctcag tatctcctag ctcgctatgt
    13681 ttttgaggag ctaaactatc gtcgctacga gtggaaatgc gatgccttaa atctgccatc
    13741 cagacgagct gcggagcgtt tgagctttat ttatgaagga accttccgtc aggcagtggt
    13801 ttataaggga cgtacgagag atacggattg gttgtctatg attgataagg actggcctca
    13861 agtcaaagat cgtttggaaa catggttgcg tcctgaaaat tttgataaaa atggacagca
    13921 gtacaagagc ttgagagaac tttaagaggt gttgagatga ttactattaa aaagcaagaa
    13981 attgtcaagc tagaggatgt tttacatctc tatcaggctg tcggttggac aaattatacc
    14041 catcaaccag agatgctgga gcaggcctta tctcattcat tagtaattta tctggcactt
    14101 gatggtgatg ctgtggtggg cttgattcgt ttggttggag atggattctc atcagtattg
    14161 gttcaggatt taatcgtttt accaatctat cagcgtcaag gaattggtag tgccttgatg
    14221 aaagaggctt tagaggatta caaagatgcc tatcaagtcc agctggtgac agaagagaca
    14281 gaaagaacct tgggcttcta tcgttctatg ggctttgaaa tcttatccac ctataattgt
    14341 atagggatga cttggatgaa tcgtaaaaaa taacaaaact tgttttttct taagcaaaat
    14401 ttaaggatgg tctagtatta tatagtcatt aaataaagac ctcctaactt tatttaataa
    14461 aatcctaaac ttttcttttt cataataatc tcccttaact ccacccaatc aggtggagtt
    14521 ttttagctct atttcaggct tttggggact attctaaaaa taatttttcg atatttttcg
    14581 gtatttttcg gattttggtc ggggaattgg cggggacttt tttagcgaat ataactaaga
    14641 aataggtctg tggtcgcttc agctagttca aactcaattt gattgtaagt gactgttaat
    14701 tgaagaactg gaactactgt aataatgatt ttgcttgtct agtagtggcg tattaaatga
    14761 gaagtgacat gtaagattgt ctcttcgttt acgaaatcaa aatttctatg aaattgatag
    14821 aatccctaac gttctcttaa tcttaaccgt cttgtcgtac agcggttgaa gaaaatgtaa
    14881 acctttgaca aaattcgtga actatgggat aataaaaagg aattgagtac tagttctata
    14941 tcataggcta gaaaagaccc caagctcacg accaaataag cttgaggtct tttttgacac
    15001 tatttgtcct tgtttagcca tttatcgact atacgaagaa cgacaccgac cacaattggt
    15061 ccgatgatag ttttgagtac taattccatc atgggctatc tcacctcctt tcgtaggcgg
    15121 tgtagcagtg tcgtagaata ttataccaca taagtgctaa acttaggagt cacccaatca
    15181 ggtggctttt ttgtttgtgg cttggttttt tgatataata gagccatgag tagaatttta
    15241 gataatgaga taatggggga tgaggagtta gtagaacgca cgctccgtcc tcagtattta
    15301 cgtgaatata tcggacagga taaggtcaag gaccagctac aaatctttat tgaagctgcc
    15361 aaaatgcggg atgaagcgct ggatcatgtg ctcttatttg ggcctccagg tctcgggaaa
    15421 acgaccatgg cctttgttat tgccaacgaa ctgggagtca atcttaagca gacgtcgggt
    15481 ccagtcattg aaaaagccgg agatctggta gctattttga atgagttaga gcctggggat
    15541 gtacttttta ttgatgagat ccatcgtttg ccaatgtcag tggaagaggt gctttatagt
    15601 gctatggagg acttctacat agatattatg attggggctg gtgagggtag tcgtagtgtt
    15661 catttggagt taccaccttt taccttgatt ggtgcgacga ctcgggctgg tatgctctcc
    15721 aatccgctac gggcacgttt tgggattaca ggccatatgg agtattatgc ccatgctgac
    15781 ttgacagaaa ttgtcgagcg gacggcagat atttttgaga tggaaatcac tcatgaggca
    15841 gcatctgagt tggccctacg tagtcgtggg acccctcgta ttgccaatcg tctcctcaag
    15901 cgcgtgcgcg attttgccca gataatgggg aatggggtaa ttgatgatat tattaccgat
    15961 aaggctttga ctatgctgga tgttgaccat gaaggtttgg actatgtgga tcaaaaaatc
    16021 cttcgtacca tgattgagat gtacagtgga ggacctgttg gtctaggaac tctttctgtg
    16081 aatatcgccg aagagcgtga gacagttgaa gatatgtatg agccttactt gattcaaaaa
    16141 ggttttatca tgcggacacg gtctggacgg gtggcgactg ctaaggcata tgagcactta
    16201 ggttatgaat acagtgaaaa ataagcaaga aatcttagag gcttttagag aaaatccaga
    16261 tatgatggcc attctgacga tcatccgaga ccttggtctg aaagactcgt ggttggcagc
    16321 aggttctgtc agaaatttca tttggaatct tttgtcagac aaatcccctt ttgatcatga
    16381 aacagatata gatgtgattt tctttgatcc agatttttct tatgaggaaa ccttattact
    16441 ggagaaaaag ctgagagagg attttcctca gtaccagtgg gaattgaaaa atcaggtcta
    16501 tatgcatcag cacagtcctc acactgcttc ctataccagt tctcgtgatg ctatgagtaa
    16561 gtatccagaa cggtgtacgg cagttggact gcgcttgaat gaagaatcag attttgaact
    16621 ctatgcacct tatggtttgg aggatatttt gaattttcaa gttcgtccaa ctcctcattt
    16681 cttagaaaat gaagaccgaa tggaactcta tcaaacacgt ttatccaaga aaaattggca
    16741 ggagaaatgg aaaaatttga tttttaaaaa tacttaagga aactttaagc tagggagtgt
    16801 acactaagtt cataagttaa gaagacctta acttaaactc ctaaaacttt ttcataataa
    16861 tctccctata aaaataaagt cgcccaatca ggcggcttat ttttttgaaa aatgggcatg
    16921 gtgcctgaga ataaatagct tagtgataga agaaaatggg gaaatatggt ataatgaaac
    16981 gatagatttt tgaataggaa taagatcatg tttggatttt ttaagaaaga taaggctgtg
    17041 gaagtagagg ttccgacaca ggttcctgct catatcggca tcatcatgga tggcaatggc
    17101 cgttgggcta aaaaacgtat gcaaccgcga gtttttggac ataaggcggg catggaagca
    17161 ttgcaaaccg tgaccaaggc agccaacaaa ctgggcgtca aggttattac ggtctatgct
    17221 ttttctacgg aaaactggac ccgtccagat caggaagtca agtttatcat gaacttgcca
    17281 gtagagtttt atgataatta tgtcccggaa ctacatgcga ataatgttaa gattcaaatg
    17341 attggggaga cagaccgcct gcctaagcaa acctttgaag ctttaaccaa ggctgaggaa
    17401 ttgactaaga acaacacagg attgattctt aattttgctc ttaactatgg tggacgtgct
    17461 gagattacac aggcgcttaa gttgatttcc caggatgttt tagatgccaa aatcaaccca
    17521 ggtgacatca cagaggaatt gattggtaac tatctcttta ctcagcattt gcctaaggac
    17581 ttacgagacc cagacttgat tatccgtact agtggagaat tacgtttgag caattttctt
    17641 ccatggcagg gagcctatag tgagctttat tttacggaca ccttatggcc tgattttgac
    17701 gaagcggcct tgcaggaagc tattcttgcc tataatcgtc gtcatcgccg atttggagga
    17761 gtttaggagg aaatatgacc caggatttac agaaaagaac cttgtttgca gggattgccc
    17821 tggctatttt cctaccaatt ttaatgattg ggggcctctt gcttcagata gcaatcggaa
    17881 tcatagccat gctagccatg catgaacttt tgaagatgag aggtctagag accatgacga
    17941 tggagggcct cttgaccctc tttgcaacct ttgcattgac cattcccttg gagaattacc
    18001 tgactttttt gccagttgat gggaatgtgg ttgcctatag tgttttgatt tcaatcatgt
    18061 taggaacgac cgtttttagc aagtcttata cgattgagga tgcggttttc cctcttgcta
    18121 tgagcttcta cgtgggcttt ggatttaatg ctttactaga tgctcgtgtt gcaggtttgg
    18181 acaaggctct cttagccttg tgtatcgtct gggcgacaga cagtggtgcc tatcttgttg
    18241 ggatgaacta tgggaaacga aagttagcac caagggtatc gcctaataaa acccttgagg
    18301 gtgccttggg tggtatttta ggagcaattt tagtaaccat tatctttatg atagttgaca
    18361 gtacagttgc tcttccatat ggaatttaca agatgtcagt ctttgctatt ttctttagca
    18421 ttgctggaca atttggtgat ttactagaaa gttcgatcaa acgtcatttt ggtgttaagg
    18481 attctgggaa atttatccct ggacatggtg gtgttttgga tcgtttcgat agtatgttgc
    18541 ttgtatttcc aatcatgcac ttatttggac tcttttaatc aaaagacgga ggaaacgcta
    18601 tgctcggaat tttaaccttt attctggttt tcgggattat tgtagtggtg cacgagttcg
    18661 ggcacttcta ctttgccaag aaatcaggga ttttagtacg tgaatttgcc atcggtatgg
    18721 gacctaaaat ttttgctcac attggcaagg atggaacggc ctataccatt cgaatcttgc
    18781 ctctgggtgg ctatgtccgc atggccggtt ggggtgatga tacaactgaa atcaagacag
    18841 gaacgcctgt tagtttgaca cttgctgatg atggtaaggt taaacgcatc aatctctcag
    18901 gtaaaaaatt ggatcaaaca gccctcccta tgcaggtgac ccagtttgat tttgaagaca
    18961 agctctttat caaaggattg gttctggaag aagaaaaaac atttgcagtg gatcacgatg
    19021 caacggttgt ggaagcagat ggtactgagg ttcggattgc acctttagat gttcaatatc
    19081 aaaatgcgac tatctggggc aaactgatta ccaattttgc aggtcctatg aacaatttta
    19141 tcttaggtgt cgttgttttt tgggttttaa tctttatgca gggtggtgtc agagatgttg
    19201 ataccaatca gttccatatc atgccccaag gtgccttggc caaggtagga gtaccagaaa
    19261 cggcacaaat taccaagatt ggctcacatg aggttagcaa ctgggaaagc ttgatccaag
    19321 ctgtggaaac agaaaccaaa gataagacgg caccgacttt ggatgtgact atttctgaaa
    19381 aggggagtga caaacaagtc actgttacac ccgaagatag tcaaggtcgt taccttctag
    19441 gtgttcaacc gggggttaag tcagattttc tatccatgtt tgtaggtggt tttacaactg
    19501 ctgctgactc agctctccga attctctcag ctctgaaaaa tctgattttc caaccggatt
    19561 tgaacaagtt gggtggacct gttgctatct ttaaggcaag tagtgatgct gctaaaaatg
    19621 gaattgaaaa tatcttgtac ttcttggcaa tgatttccat caatattggg atttttaatc
    19681 ttattccgat tccagccttg gatggtggta agattgtgct caatatccta gaagccatcc
    19741 gccgcaaacc attgaaacaa gaaattgaaa cctatgtcac cttggccgga gtggtcatca
    19801 tggttgtctt gatgattgct gtgacttgga atgacattat gcgactcttt tttagataat
    19861 cgaggaatat tatgaaacaa agtaaaatgc ctatcccaac gcttcgcgaa atgccaagcg
    19921 atgctcaagt tatcagccat gctcttatgt tgcgtgctgg ttatgttcgc caagtttcag
    19981 caggtgttta ttcttatcta ccacttgcca atcgtgtgat tgaaaaagct aaaaacatca
    20041 tgcgccaaga attcgaaaag attggtgctg ttgagatgtt ggctccagcc cttcttagtg
    20101 cagaattgtg gcgtgaatca ggtcgttacg aaacctatgg tgaagacctt tacaaactaa
    20161 aaaaccgtga aaaatcagac tttatcttag gtccaactca cgaagaaacc tttacagcta
    20221 ttgtccgtga ttctgttaaa tcttacaagc aattgccact caacctttat caaattcagc
    20281 ccaagtatcg tgatgaaaaa cgcccacgta atggacttct tcgtacacgt gagtttatca
    20341 tgaaggatgc ttatagtttc cacgctaact atgatagttt ggatagtgtt tatgatgagt
    20401 acaaagcagc ctatgagcgt attttcactc gtagtggttt agacttcaag gctattattg
    20461 gtgacggtgg agccatgggt ggtaaggata gccaagaatt tatggccatt acatctgctc
    20521 gtacagacct tgaccgctgg gttgtcttgg acaagtcagt tgcctcattt gacgaaattc
    20581 ctgcagaagt gcaagaagaa atcaaggcag aattgctcaa atggatagtc tctggtgaag
    20641 ataccattgc ttactcaagt gagtctagct atgcagctaa cttagaaatg gcaacaaacg
    20701 agtacaaacc aagcaaccgt gttgtcgctg aagaagaagt tactcgtgtt gcaacgccag
    20761 atgttaaatc aattgatgaa gttgcagctt tcctcaatgt tccagaagaa caaacgatta
    20821 aaaccctctt ctacattgca gatggtgagc ttgttgcagc ccttctagtt ggaaatgacc
    20881 aactcaacga agtcaagttg aaaaaccact taggagcaga tttctttgac gttgctagcg
    20941 aagaagaagt ggcgaatgtt gttcaagcag gatttggttc acttggacca gttggtttgc
    21001 cagagaatat taaaattatt gcagatcgta aggtgcaaga tgttcgcaat gcagttgtcg
    21061 gtgctaacga agatggctac cacttgactg gtgtgaaccc aggccgtgat tttactgcag
    21121 aatatgtgga tatccgtgaa gttcgtgagg gtgaaatttc cccagatgga caaggtgtcc
    21181 ttaactttgc gcgtggtatt gagatcggtc atattttcaa actcggaact cgctactcag
    21241 caagcatggg agcagatgtc ttggatgaaa atggtcgtgc tgtgccaatc atcatgggat
    21301 gttacggtat cggtgtcagc cgtcttcttt cagcagtgat ggagcaacac gctcgcctct
    21361 ttgttaacaa aacgccaaaa ggtgaatacc gttacgcttg gggaatcaat ttccctaaag
    21421 aattggcacc atttgatgtg catttgatta ctgtcaatgt caaggatgaa gaagcgcaag
    21481 ccttgacaga aaaacttgaa gcaagcttga tgggagctgg ttatgaagtc ttgacagatg
    21541 accgtaacga acgtgtcggt gttaaattta gcgatagtga cttgattggt cttccaatcc
    21601 gtatcactgt tggtaaaaaa gcggccgatg gcattgtaga agttaagatc aaggcaactg
    21661 gtgacaccat tgaggttcat gcagataacg tgcttgaaac gcttgaaatc ctaagcaaga
    21721 aataaaaact ataatcagaa gaaaaacaag gaaaaaatgt aactagtttt taccttgttt
    21781 tttctgtata atgggagaaa tgagtagata aagaggtaaa tgttatgcta agatttccaa
    21841 aggattttgt ctggggatcc tctacttctg gaccgcagac agaaggacgt gtagctggtg
    21901 acggtaaggg agacaatctc tgggattact ggttccaagt ggagccaaat cgttactata
    21961 atgggattgg ttcagataag acatcgactt tttatgaaaa ttgggagcgg gatattgagc
    22021 ttttgttaga gactggtcac acagtctttc ggacttctat tcagtggtca cggatttttc
    22081 cacaaggctg tggaaaagtc aaccctcaag gtgtggattt ttatcgtaag gtctttgagg
    22141 ctattaaggc taaaggaatt cgtctgttag tcaatctcta tcattttgat ttaccttttg
    22201 cccttcaaga ggatggtgat ggttgggaaa ataaggcgac agtctcagcc tatgaagact
    22261 atgctcgttt ttgttttgag acttatggag atttagtgga tcaatggatt acctttaacg
    22321 agctcatcgt tcctgtagaa tttggttatt tttatgatgc ccattatcca cataaggtgg
    22381 atgcagaggc agctgttaag gtagcctatc atacacaatt ggccagcagc cgggctgtta
    22441 aggcttgcca tgaacttttg cctgattcca agattgggat tgtcctcaac ttgacaccgg
    22501 cttatccacg tagccagcat cctgctgatg tcaaggcagc tcgtattgcg gccctttttc
    22561 aggcccaatc tttcttagat ccatctgtct tggggactta tccacaggag ttggtagaaa
    22621 tcttgcatga acacggtctt ttacctgatg ctacagagga agagttggaa ctcattcatg
    22681 ataatacggt ggacttcctt ggtgtgaact actatcaacc tttgcgtgtt atggctcctc
    22741 gatttgctaa gcatccagag agtccactct taccagaaca tttttacgag ccttatgtga
    22801 tgcctggacg taaaatcaat tctcaccgtg gttgggagat ttatgagcaa gggatttatg
    22861 acatcgccca aaatatcaag gaaaattatg gcaatattga atggatgttg actgagaatg
    22921 gtatgggtgt tgaaggggaa gaaaaattcc gtcaagatgg aatgattcaa gatgattacc
    22981 gtattgactt tgtaaaaggt catcttcgtg aacttcaccg tgccattgaa gatggtgcca
    23041 actgtaaggg ctacttgatt tggaccttta ttgactgctg gtcatggctc aacagctata
    23101 aaaatcgcta tggtttggtc gaattagact tggaaacgca agaacgtcgt ctgaagaaat
    23161 caggccactg gttcaaaaaa ttaagcgata ataatggatt ttaaaaagga ctctgactga
    23221 ttatcccaat cggtcagagt tttttgctta caggagctta atttgaacta taccaatttt
    23281 tactcttgac aagtgaaaga aacaagtata tactgttttt gctgattcta taaaagatga
    23341 attagactat accaatttta aggagaaagc acagcttgcc tgtgtcgtat atactatgtg
    23401 tggaattgtt ggtgttgttg gaaacacaaa tgcaactgat attttgattc aagggcttga
    23461 aaagcttgaa taccgtggct atgattctgc gggaattttt gtcctagatg gtgctgataa
    23521 ccatttggtg aaggctgttg gtcgtatcgc agaattgtct gccaagacag ctggtgttga
    23581 gggaacaact ggtatcggac atactcgttg ggcaactcat gggaaaccaa cggaagacaa
    23641 tgctcaccca caccgctctg agacagaacg ttttgtcttg gttcacaatg gggtgattga
    23701 aaactacctt gaaattaaag aagaatacct tgctgggcac cacttcaaag ggcaaacaga
    23761 tacggaaatc gccgtacatt tgattggaaa atttgcggaa gaagacggtc tctcagttct
    23821 tgaagccttt aaaaaagctc ttcatattat ccgtggttca tatgcctttg ccttgattga
    23881 ctctgaaaat ccagatgtca tctatgtagc gaaaaacaaa tctccacttt tgattggtct
    23941 tggggaaggc tacaatatgg tctgctcaga tgctatggct atgattcgtg aaaccaacca
    24001 atacatggaa attcatgacc aagagttggt aatcgtcaag gctgatagcg tggaagttca
    24061 agactatgat ggaaatcgtc gtgagcgtgc tagctacact gctgaacttg acttgtcaga
    24121 tatcggtaag ggaacttacc cttactacat gctcaaggaa attgacgagc aaccaactgt
    24181 tatgcggaaa ctcatccaag cctacacaga tgaggctggt caagttgtcg tagacccaga
    24241 tatcattaag gctgttcaag acgcagaccg catctacatc cttgcagctg gaacatctta
    24301 ccatgcagga tttgcttcta agaagatgtt ggaagaattg acagatacac cagttgaact
    24361 tggaatctca tctgagtggg gctacggtat gccacttctc agcaagaaac cactcttcat
    24421 ctttatcagc caatctggtg aaacagcgga tagtcgtcaa gttttggtca aggctaatga
    24481 aatgggaatt ccaagcttaa cagtgacaaa tgttccaggt tcaaccctct cacgtgaagc
    24541 caactatacc atgctccttc acgcaggtcc tgaaattgcc gtggcatcaa ctaaagccta
    24601 tacagcgcaa atcgcagccc ttgccttcct tgcaaaagca gtcggagaag caaatggtaa
    24661 tgctaaagcg caagcctttg acctggttca tgaattgtca atcgtagctc agtctattga
    24721 atcaactctt tcagagaaag aaaccattga agccaaggtt cgtgaacttc ttgaaacaac
    24781 tcgtaacgcc ttttacatcg gacgtggtca agattattac gtagccatgg aagcaagtct
    24841 caaactcaaa gagatttctt atatccagtg tgaaggtttt gcggcaggag aactcaagca
    24901 cggaaccatt gccttgattg aagaaggaac gcctgttttg gctctcttgt cagatccagt
    24961 tcttgccaac catactcgtg gaaatatcca agaggtcgca gcccgtggtg ccaaagtcct
    25021 cactatcgca gaagagaatg tagccaaaga taccgacgat atcgtcctta cgaccgtaca
    25081 tccatacctc tcaccaattt caatggtcgt accaacgcaa ttagtcgctt actttgcaac
    25141 cctccaccgt ggcctcgatg tggacaaacc acgtaacctt gccaagtcag taacggtaga
    25201 ataagctaaa aaagtctagt tatctaggct ttttcttgtg agcaaattgg ttgcttgtac
    25261 tcaagattcg tgttatactc ttagaaaatc tcttcaaacc acgtcaccgt cgccttgccg
    25321 taggtatggt tactga
//
LOCUS       DAVBBO010000029        24327 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ST1
            SAMEA2066453-rid20184263.denovo.029, whole genome shotgun sequence.
ACCESSION   DAVBBO010000029 DAVBBO010000000
VERSION     DAVBBO010000029.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2066453
            Sequence Read Archive: ERR351777
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 24327)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 24327)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980402.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980402.1
            Genome Coverage       :: 176x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:17:33
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,141
            CDSs (total)                      :: 2,104
            Genes (coding)                    :: 1,953
            CDSs (with protein)               :: 1,953
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 16S)
            partial rRNAs                     :: 1 (23S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 151
            CDSs (without protein)            :: 151
            Pseudo Genes (ambiguous residues) :: 0 of 151
            Pseudo Genes (frameshifted)       :: 73 of 151
            Pseudo Genes (incomplete)         :: 76 of 151
            Pseudo Genes (internal stop)      :: 40 of 151
            Pseudo Genes (multiple problems)  :: 32 of 151
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..24327
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2066453-rid20184263.denovo.029"
                     /strain="ST1"
                     /db_xref="taxon:1313"
     gene            complement(<1..618)
                     /locus_tag="VQU30_001170"
     CDS             complement(<1..618)
                     /locus_tag="VQU30_001170"
                     /EC_number="2.7.4.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001050429.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenylate kinase"
                     /protein_id="HET2447285.1"
                     /translation="MNLLIMGLPGAGKGTQAAKIVEQFHVAHISTGDMFRAAMANQTE
                     MGVLAKSYIDKGELVPDEVTNGIVKERLSQDDIKETGFLLDGYPRTIEQAHALDKTLA
                     ELGIELEGIINIEVNPDSLLERLSGRIIHRVTGETFHKVFNPPVDYKEEDYYQREDDK
                     PETVKRRLDVNIAQGEPIIAHYRAKGLVHDIEGNQDINDVFSDIEK"
     gene            complement(769..2079)
                     /gene="secY"
                     /locus_tag="VQU30_001171"
     CDS             complement(769..2079)
                     /gene="secY"
                     /locus_tag="VQU30_001171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001860634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecY"
                     /protein_id="HET2447286.1"
                     /translation="MFFKLLREALKVKQVRSKILFTIFIVLVFRIGTSITVPGVNANS
                     LNALSGLSFLNMLSLVSGNALKNFSIFALGVSPYITASIVVQLLQMDILPKFVEWGKQ
                     GEVGRRKLNQATRYIALVLAFVQSIGITAGFNTLAGAQLIKTALTPQVFLTIGIILTA
                     GSMIVTWLGEQITDKGYGNGVSMIIFAGIVSSIPEMIQGIYVDYFVNVPSSRITSSII
                     FVIILIITVLLIIYFTTYVQQAEYKIPIQYTKVAQGAPSSSYLPLKVNPAGVIPVIFA
                     SSITAAPAAILQFLSATGHDWAWVRVAQEMLATTSPTGIAMYALLIILFTFFYTFVQI
                     NPEKAAESLQKSGAYIHGVRPGKGTEEYMSKLLRRLATVGSLFLGVISILPIAAKDVF
                     GLSDVVAFGGTSLLIIISTGIEGIKQLEGYLLKRKYVGFMDRTE"
     gene            complement(2092..2532)
                     /gene="rplO"
                     /locus_tag="VQU30_001172"
     CDS             complement(2092..2532)
                     /gene="rplO"
                     /locus_tag="VQU30_001172"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004225266.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L15"
                     /protein_id="HET2447287.1"
                     /translation="MKLHELKPAEGSRKVRNRVGRGTSSGNGKTSGRGQKGQKARSGG
                     GVRLGFEGGQTPLFRRLPKRGFTNINAKEYAIVNLDQLNVFEDGAEVTPVVLIEAGIV
                     KAEKSGIKILGNGELTKKLTVKAAKFSKSAEEAITAKGGSVEVI"
     gene            complement(2677..2901)
                     /gene="rpmD"
                     /locus_tag="VQU30_001173"
     CDS             complement(2677..2901)
                     /gene="rpmD"
                     /locus_tag="VQU30_001173"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012386624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L30"
                     /protein_id="HET2447288.1"
                     /translation="MVFQFLIWHKKGDKMAQIKITLTKSPIGRIPSQRKTVVALGLGK
                     LNSSVIKEDNAAIRGMITAVSHLVTVEEVN"
     gene            complement(2873..3367)
                     /gene="rpsE"
                     /locus_tag="VQU30_001174"
     CDS             complement(2873..3367)
                     /gene="rpsE"
                     /locus_tag="VQU30_001174"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018376782.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S5"
                     /protein_id="HET2447289.1"
                     /translation="MAFKDNAVELEERVVAVNRVTKVVKGGRRLRFAALVVVGDHNGR
                     VGFGTGKAQEVPEAIRKAVDDAKKNLIEVPMVGTTIPHEVLSEFGGAKVLLKPAVEGS
                     GVAAGGAVRAVVELAGVADITSKSLGSNTPINIVRATVEGLKQLKRAEEIAALRGISV
                     SDLA"
     gene            complement(3385..3741)
                     /gene="rplR"
                     /locus_tag="VQU30_001175"
     CDS             complement(3385..3741)
                     /gene="rplR"
                     /locus_tag="VQU30_001175"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018374469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L18"
                     /protein_id="HET2447290.1"
                     /translation="MISKPDKNKLRQKRHRRVRGKLSGTADRPRLNVFRSNTGIYAQV
                     IDDVAGVTLASASTLDKEVSKGTKTEQAVAVGKLVAERANAKGISEVVFDRGGYLYHG
                     RVKALADAARENGLKF"
     gene            complement(3825..4361)
                     /gene="rplF"
                     /locus_tag="VQU30_001176"
     CDS             complement(3825..4361)
                     /gene="rplF"
                     /locus_tag="VQU30_001176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L6"
                     /protein_id="HET2447291.1"
                     /translation="MSRIGNKVIVLPAGVELANNDNVVTVKGPKGELTREFSKDIEIR
                     VEGTEITLHRPNDSKEMKTIHGTTRALLNNMVVGVSEGFKKELEMRGVGYRAQLQGSK
                     LVLAVGKSHPDEVEAPEGITFELPNPTTIVVSGISKEVVGQTAAYVRSLRSPEPYKGK
                     GIRYVGEFVRRKEGKTGK"
     gene            complement(4553..4951)
                     /gene="rpsH"
                     /locus_tag="VQU30_001177"
     CDS             complement(4553..4951)
                     /gene="rpsH"
                     /locus_tag="VQU30_001177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009754342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S8"
                     /protein_id="HET2447292.1"
                     /translation="MVMTDPIADFLTRIRNANQAKHEVLEVPASNIKKGIAEILKREG
                     FVKNVEIIEDDKQGVIRVFLKYGPNGEKVITNLKRVSKPGLRVYKKREDLPKVLNGLG
                     IAILSTSEGLLTDKEARQKNVGGEVIAYVW"
     gene            complement(5236..5505)
                     /gene="rpsN"
                     /locus_tag="VQU30_001178"
     CDS             complement(5236..5505)
                     /gene="rpsN"
                     /locus_tag="VQU30_001178"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006738440.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S14"
                     /protein_id="HET2447293.1"
                     /translation="MAKKSMVAREAKRQKIVDRYAEKRAALKAAGDYEGLSKLPRNAS
                     PTRLHNRCRVTGRPHSVYRKFGLSRIAFRELAHKGQIPGVTKASW"
     gene            complement(5523..6065)
                     /gene="rplE"
                     /locus_tag="VQU30_001179"
     CDS             complement(5523..6065)
                     /gene="rplE"
                     /locus_tag="VQU30_001179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018376779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L5"
                     /protein_id="HET2447294.1"
                     /translation="MANRLKEKYLNEVVPALTEQFNYSSVMAVPKVDKIVLNMGVGEA
                     VSNAKSLEKAAEELALISGQKPLITKAKKSIAGFRLREGVAIGAKVTLRGERMYEFLD
                     KLVSVSLPRVRDFHGVPTKSFDGRGNYTLGVKEQLIFPEINFDDVDKTRGLDIVIVTT
                     ANTDEESRALLTGLGMPFAK"
     gene            complement(6089..6394)
                     /gene="rplX"
                     /locus_tag="VQU30_001180"
     CDS             complement(6089..6394)
                     /gene="rplX"
                     /locus_tag="VQU30_001180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011921687.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L24"
                     /protein_id="HET2447295.1"
                     /translation="MFVKKGDKVRVIAGKDKGTEAVVLTALPKVNKVIVEGVNIVKKH
                     QRPTNELPQGGIIEKEAAIHVSNVQVLDKNGVAGRVGYKFVDGKKVRYNKKSGEVLD"
     gene            complement(6472..6840)
                     /gene="rplN"
                     /locus_tag="VQU30_001181"
     CDS             complement(6472..6840)
                     /gene="rplN"
                     /locus_tag="VQU30_001181"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012727667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L14"
                     /protein_id="HET2447296.1"
                     /translation="MIQTETRLKVADNSGAREILTIKVLGGSGRKFANIGDVIVASVK
                     QATPGGAVKKGDVVKAVIVRTKSGARRADGSYIKFDENAAVIIREDKTPRGTRIFGPV
                     ARELREGGFMKIVSLAPEVL"
     gene            complement(6866..7126)
                     /gene="rpsQ"
                     /locus_tag="VQU30_001182"
     CDS             complement(6866..7126)
                     /gene="rpsQ"
                     /locus_tag="VQU30_001182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006738952.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S17"
                     /protein_id="HET2447297.1"
                     /translation="MERNNRKVLVGRVVSDKMDKTITVVVETKRNHPVYGKRINYSKK
                     YKAHDENNVAKEGDIVRIMETRPLSATKRFRLVEVVEEAVII"
     gene            complement(7151..7357)
                     /locus_tag="VQU30_001183"
     CDS             complement(7151..7357)
                     /locus_tag="VQU30_001183"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006739716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L29"
                     /protein_id="HET2447298.1"
                     /translation="MKLNEVKEFVKELRGLSQEELAKRENELKKELFELRFQAATGQL
                     EQTARLKEVKKQIARIKTVQSEAK"
     gene            complement(7367..7780)
                     /gene="rplP"
                     /locus_tag="VQU30_001184"
     CDS             complement(7367..7780)
                     /gene="rplP"
                     /locus_tag="VQU30_001184"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003029477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L16"
                     /protein_id="HET2447299.1"
                     /translation="MLVPKRVKHRREFRGKMRGEAKGGKEVAFGEYGLQATTSHWITN
                     RQIEAARIAMTRYMKRGGKVWIKIFPHKSYTAKAIGVRMGSGKGAPEGWVAPVKRGKV
                     MFEIAGVSEEIAREALRLASHKLPVKCKFVKREAE"
     gene            complement(7784..8437)
                     /gene="rpsC"
                     /locus_tag="VQU30_001185"
     CDS             complement(7784..8437)
                     /gene="rpsC"
                     /locus_tag="VQU30_001185"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000529931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S3"
                     /protein_id="HET2447300.1"
                     /translation="MGQKVHPIGMRVGIIRDWDAKWYAEKEYADYLHEDLAIRKFVQK
                     ELADAAVSTIEIERAVNKVNVSLHTAKPGMVIGKGGANVDALRAKLNKLTGKQVHINI
                     IEIKQPDLDAHLVGEGIARQLEQRVAFRRAQKQAIQRAMRAGAKGIKTQVSGRLNGAD
                     IARAEGYSEGTVPLHTLRADIDYAWEEADTTYGKLGVKVWIYRGEVLPARKNTKGGK"
     gene            complement(8450..8794)
                     /gene="rplV"
                     /locus_tag="VQU30_001186"
     CDS             complement(8450..8794)
                     /gene="rplV"
                     /locus_tag="VQU30_001186"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018371349.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L22"
                     /protein_id="HET2447301.1"
                     /translation="MAEITSAKAMARTVRVSPRKSRLVLDNIRGKSVADAIAILTFTP
                     NKAAEIILKVLNSAVANAENNFGLDKANLVVSEAFANEGPTMKRFRPRAKGSASPINK
                     RTAHITVAVAEK"
     gene            complement(8806..9087)
                     /gene="rpsS"
                     /locus_tag="VQU30_001187"
     CDS             complement(8806..9087)
                     /gene="rpsS"
                     /locus_tag="VQU30_001187"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000533767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S19"
                     /protein_id="HET2447302.1"
                     /translation="MGRSLKKGPFVDEHLMKKVEAQANDEKKKVIKTWSRRSTIFPSF
                     IGYTIAVYDGRKHVPVYIQEDMVGHKLGEFAPTRTYKGHAADDKKTRRK"
     gene            complement(9191..10024)
                     /gene="rplB"
                     /locus_tag="VQU30_001188"
     CDS             complement(9191..10024)
                     /gene="rplB"
                     /locus_tag="VQU30_001188"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019790357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L2"
                     /protein_id="HET2447303.1"
                     /translation="MGIRVYKPTTNGRRNMTSLDFAEITTSTPEKSLLVALKSKAGRN
                     NNGRITVRHQGGGHKRFYRLVDFKRNKDNVEAVVKTIEYDPNRSANIALVHYTDGVKA
                     YIIAPKGLEVGQRIVSGPEADIKVGNALPLANIPVGTLIHNIELKPGRGGELVRAAGA
                     SAQVLGSEGKYVLVRLQSGEVRMILGTCRATVGVVGNEQHGLVNLGKAGRSRWKGIRP
                     TVRGSVMNPNDHPHGGGEGKAPVGRKAPSTPWGKPALGLKTRNKKAKSDKLIVRRRNE
                     K"
     gene            complement(10042..10338)
                     /locus_tag="VQU30_001189"
     CDS             complement(10042..10338)
                     /locus_tag="VQU30_001189"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007518994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L23"
                     /protein_id="HET2447304.1"
                     /translation="MNLYDVIKKPVITESSMAQLEAGKYVFEVDTRAHKLLIKQAVEA
                     AFEGVKVANVNTINVKPKAKRVGRYTGFTNKTKKAIITLTADSKAIELFAAEAE"
     gene            complement(10338..10961)
                     /gene="rplD"
                     /locus_tag="VQU30_001190"
     CDS             complement(10338..10961)
                     /gene="rplD"
                     /locus_tag="VQU30_001190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677212.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L4"
                     /protein_id="HET2447305.1"
                     /translation="MANVTLFDQTGKEAGQVVLSDAVFGIEPNESVVFDVIISQRASL
                     RQGTHAVKNRSAVSGGGRKPWRQKGTGRARQGSIRSPQWRGGGVVFGPTPRSYGYKLP
                     QKVRRLALKSVYSEKVAENKFVAVDALSFTAPKTAEFAKVLAALSIDSKVLVILEEGN
                     EFAALSARNLPNVKVATATTASVLDIANSDKLLVTQAAISKIEEVLA"
     gene            complement(10986..11612)
                     /gene="rplC"
                     /locus_tag="VQU30_001191"
     CDS             complement(10986..11612)
                     /gene="rplC"
                     /locus_tag="VQU30_001191"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002986659.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L3"
                     /protein_id="HET2447306.1"
                     /translation="MTKGILGKKVGMTQIFTEAGELIPVTVIEATPNVVLQVKTVETD
                     GYNAIQVGFDDKREVLSNKPAKGHVAKANTAPKRFIREFKNVEGLEVGAEITVETFAA
                     GDVVDVTGTSKGKGFQGVIKRHGQSRGPMAHGSRYHRRPGSMGPVAPNRVFKGKNLAG
                     RMGGDRVTIQNLEVVQVVPEKNVILIKGNVPGAKKSLITIKSAVKAGK"
     gene            complement(11828..12136)
                     /gene="rpsJ"
                     /locus_tag="VQU30_001192"
     CDS             complement(11828..12136)
                     /gene="rpsJ"
                     /locus_tag="VQU30_001192"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003046044.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S10"
                     /protein_id="HET2447307.1"
                     /translation="MANKKIRIRLKAYEHRTLDTAAAKIVESATRTGAQVAGPIPLPT
                     ERSLYTIIRATHKYKDSREQFEMRTHKRLIDIVNPTQKTVDALMKLDLPSGVNVEIKL
                     "
     gene            complement(12402..13019)
                     /locus_tag="VQU30_001193"
     CDS             complement(12402..13019)
                     /locus_tag="VQU30_001193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000725987.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribulokinase"
                     /protein_id="HET2447308.1"
                     /translation="MKKKDLVDQLVSEIETGKVRTLGIYGHGASGKSTFAQELYQALD
                     STTVNLLETDPYITSGRYLVVPKDAPNQKVTASLPVAHELESLQRDILALQAGMDVLT
                     IEEPWKASEVLSGAKPILIVEGMSVGFLPKELFEKTICFYTDEETELKRRLARDTTVR
                     NRDASFILASHQMRREQYLRYYKETESKADILVDQSEDKFDVKRT"
     gene            complement(13016..13606)
                     /gene="nrdG"
                     /locus_tag="VQU30_001194"
     CDS             complement(13016..13606)
                     /gene="nrdG"
                     /locus_tag="VQU30_001194"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001064213.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic ribonucleoside-triphosphate reductase
                     activating protein"
                     /protein_id="HET2447309.1"
                     /translation="MNNPKPQEWKSEELSQGRIIDYKAFNFVDGEGVRNSLYVAGCMF
                     HCEGCYNVATWSFNAGIPYTAELEEQIMADLAQPYVQGLTLLGGEPFLNTGILLPLVK
                     RIRKELPDKDIWSWTGYTWEEMMLETPDKLELLSLIDILVDGRYDRTKRNLMLQFRGS
                     SNQRIIDVQKSLKSGQVVIWDKLNDGKEIYEQVKRE"
     gene            complement(13599..14105)
                     /locus_tag="VQU30_001195"
     CDS             complement(13599..14105)
                     /locus_tag="VQU30_001195"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000423399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HET2447310.1"
                     /translation="MELRRPRLADKKAVLDMMTEFEKSQSAHDGGFWDVEDFSYEEWL
                     EGNRNKEMGIWLPENRVPSIQFVLFGESGCALGFLNLRLRLNEGLLNYAGHIGYSIRP
                     SERGKGYAKETLRQGLQVAKEKNIKKALVTCSVNNPASRAVILANGGIFEDARNGVER
                     YWIEVANE"
     gene            complement(14149..14289)
                     /locus_tag="VQU30_001196"
     CDS             complement(14149..14289)
                     /locus_tag="VQU30_001196"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000521630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2447311.1"
                     /translation="MGKYQLDDKGRAQVTRYHEKHSKGGAGKKERLLSFREQFLNKNK
                     KK"
     gene            complement(14301..16508)
                     /gene="nrdD"
                     /locus_tag="VQU30_001197"
     CDS             complement(14301..16508)
                     /gene="nrdD"
                     /locus_tag="VQU30_001197"
                     /EC_number="1.17.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004239081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic ribonucleoside-triphosphate reductase"
                     /protein_id="HET2447312.1"
                     /translation="MIALEEKITILPTLFVEKRDGRRVVFDVDKIDKALHKAADKVMD
                     VTPLVEKRLNDLTERIITEIHSRFPQGIKIYEIQNIVEHELLEAKEYALAEEYITYRT
                     QRDFERSKATDINFSIHKLLNKDQTVVNENANKDSDVFNTQRDLTAGIVGKSIGLQML
                     PKHVANAHQKGDIHYHDLDYSPYTPMTNCCLIDFKGMLENGFKIGNAEVESPKSIQTA
                     TAQISQIIANVASSQYGGCSADRIDEILAPYAEKNYQKHLKDAEEWVLPEKREDYAWK
                     KTQKDIYDAMQSLEYEINTLFTSNGQTPFTSLGFGLGTSRFEREIQKAILNIRIKGLG
                     SEHRTAIFPKLIFTLKRGLNLEEGTPNYDIKQLALECATKRMYPDVLSYDKIVDLTGS
                     FKVPMGCRSFLQGWKDENGVEVNSGRMNLGVVTVNLPRIALESEGDMNKFWEIFNERM
                     NIAEDALVYRVERTKEATPANAPILYQYGAFGHRLGKEESVDQLFKNCRATVSLGYIG
                     LYEVATVFFGNSWESNPDAKEFTLDIIHDMKRRVEEWSDQYGYHFSIYSTPSESLTDR
                     FCRLDIDKFGSIPDITDKEYYTNSFHYDVRKNPTPFEKLDFEKVYPEAGASGGFIHYC
                     EYPVLQQNPKALEAVWDYAYDRVGYLGTNTPIDRCYKCDFEGDFEPTERGFACPNCGN
                     SDPKTVDVVKRTCGYLGNPQARPMVNGRHKEIAARVKHMNGSTIKIAGHQVTN"
     gene            complement(16628..18166)
                     /locus_tag="VQU30_001198"
     CDS             complement(16628..18166)
                     /locus_tag="VQU30_001198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844448.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="damage-inducible protein CinA"
                     /protein_id="HET2447313.1"
                     /translation="MSVYGRVEEVHKENREPLEYQIEQESHHRESSRLPLVKILLWST
                     LVTGITLGVPLLLDLMSAQEVQDFYAGWALHQTGKIYSDYYGSQGLLYYLLTYVSQGG
                     FFFAIFEWLALVAGGFFLFRSADTLTEQGDQAGHLVTIFYMLVTGLAFGGGYATLLAL
                     PFLFAAFSLVAAYLSNPSHDKGFVRIGLALAGGFFFAPLSSLLFIAVVSLGLLVFNLG
                     HRRFAHGFYQFLAVALGFSLVFYPTAYYSAATGSFGDAISGIRYPIDSIRFDFTSKIL
                     ENMFFYGLLSLGLGFVVCIFLGLFQSKPFKLYVISVPASLVVILGLILLFFSQEPLHA
                     SYLMVVFPVFLLLLVTNIKSQQRGRSARRSRRETPVSLWSRFFKGNLYLLVFGFVYLL
                     SVPFLMKFVLYPVPYQERNRLADLVKEETNTEDAIYAWDDTATLYRKSERLSPSAILS
                     PLHYTATEENRNKLLNDLKEKQPKVIVVNDKVVVWSEVETLLKENYQQVKTDYSEFKV
                     YKIK"
     gene            complement(18203..18346)
                     /locus_tag="VQU30_001199"
     CDS             complement(18203..18346)
                     /locus_tag="VQU30_001199"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000956126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2447314.1"
                     /translation="MLTKEEVNDMIEFKQTHLHRFREIETFVKLCKKSLKQPSQADNP
                     RTF"
     gene            complement(18424..19956)
                     /gene="cls"
                     /locus_tag="VQU30_001200"
     CDS             complement(18424..19956)
                     /gene="cls"
                     /locus_tag="VQU30_001200"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000877342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cardiolipin synthase"
                     /protein_id="HET2447315.1"
                     /translation="MKYRKFQLLMSKYGFSLSIMLLELCLVFGLFLYLGRMAPILWIT
                     VLILLSIITIISIVNRNTTPENKVTWLLVAFVPVFGPLLYLMFGERRLSKKEIKQLKK
                     LGSMHFQEANSQLLKEKLKESDKAAYGVIKSLLSMDTNADIYDQTASTFFPNGEAMWK
                     KMVEDLKKAEKFIFLEYYIIEEGLMWNRILDILEQKVAQGVEVKMLYDDIGCMATLTG
                     DYAHRLRQLGIEAHKFNKVIPRLTVAYNNRDHRKILIVDGQIAYTGGVNLADEYINHV
                     ERFGYWKDSGIRLDGLAVKALTRLFLTTWYINRGEISDFDQYHLENHSIPSDGLTIPY
                     GSGPKPIFRAQVGKKVYQSLINQATESVYITTPYLIIDYDLTETIKNAAMRGVDVRII
                     TPYIPDKKFIQLVTRGAYPDLLSAGVRIYEYSPGFIHSKQMLVDEDFAVVGTINLDYR
                     SLVHHYENAVLLYKTPSIREIARDFRNIFADSQEVYPHSIKTSWYQKLVKEIAQLFAP
                     IL"
     gene            complement(20102..20659)
                     /locus_tag="VQU30_001201"
     CDS             complement(20102..20659)
                     /locus_tag="VQU30_001201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001816192.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipocalin/fatty acid-binding family protein"
                     /protein_id="HET2447316.1"
                     /translation="MTPLFELVILGELLVRENFSKLVAERKFIMKLKRFTLSLASLAS
                     FSLLVACSQRAQQVQQPVAQQQVQQPAQQPAQQNTNTANAGGNQNQAAPVQNQPVAQP
                     TDIDGTYTGQDDGDRITLVVTGTTGTWTELESDGDQKVKQVTFDSANQRMIIGDDVKI
                     YTVNGNQIVVDDMDRDPSDQIVLTK"
     gene            complement(20656..21906)
                     /locus_tag="VQU30_001202"
     CDS             complement(20656..21906)
                     /locus_tag="VQU30_001202"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000464354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional folylpolyglutamate
                     synthase/dihydrofolate synthase"
                     /protein_id="HET2447317.1"
                     /translation="MFEVEEWLHSRIGLNFRSGLGRIQQAVDLLGNPEQSYPIIHVTG
                     TNGKGSTIAFMRELFMGHGKKVATFTSPHIVSINDRICINGQPIADADFIRLADQVKE
                     MEKTLLQTPDQLSFFEMLTLVAFLYFREQEVDLVLLEVGIGGLLDTTNVVTGELAVIT
                     SIGLDHQETLGDSLEAIAEQKAGIFKAGKKAVIAKLPPEARLVCQKKAESLAVNLYQA
                     GQDFLMLNGDFSSSLLNFSQLNIGLEGVYQQENAALALQTFLLFMGEGKEAVDEQAVR
                     KALEQTHWAGRLERIRPQIYLDGAHNLPALTRLVEFIKEKEQEGYRPQILFGALKRKD
                     YQGMLGYLTEKLPQVELKVTGFDYQGALDERDVTGYDIVSSCREFISSFEERADAQDL
                     LFVTGSLYFISEVRGYLLDREQIN"
     gene            complement(22114..22419)
                     /locus_tag="VQU30_001203"
     CDS             complement(22114..22419)
                     /locus_tag="VQU30_001203"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008809966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1292 domain-containing protein"
                     /protein_id="HET2447318.1"
                     /translation="MSHDHNHDHEERELITLVDEQGNETLFEILLTIDGKEEFGKNYV
                     LLVPVNAEEDEDGQVEIQAYSFIENEDGTEGELQPIPEDSEDEWNMIEEVFNSFMEE"
     gene            complement(22435..22854)
                     /gene="ruvX"
                     /locus_tag="VQU30_001204"
     CDS             complement(22435..22854)
                     /gene="ruvX"
                     /locus_tag="VQU30_001204"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002939356.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction resolvase RuvX"
                     /protein_id="HET2447319.1"
                     /translation="MRIMGLDVGSKTVGVAISDPLGFTAQGLEIIQINEEQGQFGFDR
                     VKELVDTYKVERFVVGLPKNMNNTSGPRVEASQAYGAKLEEFFGLPLDYQDERLTTVA
                     AERMLIEQADISRNKRKKVIDKLAAQLILQNYLDRKF"
     gene            complement(22858..23124)
                     /locus_tag="VQU30_001205"
     CDS             complement(22858..23124)
                     /locus_tag="VQU30_001205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004250500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IreB family regulatory phosphoprotein"
                     /protein_id="HET2447320.1"
                     /translation="MGFTEETVRFKLDDSNKKEISETLTDVYASLNDKGYNPINQIVG
                     YVLSGDPAYVPRYNNARNQIRKYERDEIVEELVRYYLKGQGVDL"
     gene            complement(23211..23780)
                     /locus_tag="VQU30_001206"
     CDS             complement(23211..23780)
                     /locus_tag="VQU30_001206"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000725124.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HET2447321.1"
                     /translation="MKKIVLVSLAFLFVLVGCGQKKETGPATKTEKDTLQSALPVIEN
                     AEKNTVVTKTLVLPKSDDGSQQTQTITYKDKTFLSLTIQQKRPVSDELKTYIDQHGVE
                     ETQKALLEAEEKDKSIIEARKLAGFKLETKLLSATELQTTTSFDFQVLDVKKASQLEH
                     LKNIGLENLLKNEPSKYISDRLANGATEQ"
     gene            complement(23846..24244)
                     /gene="spx"
                     /locus_tag="VQU30_001207"
     CDS             complement(23846..24244)
                     /gene="spx"
                     /locus_tag="VQU30_001207"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017768833.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator Spx"
                     /protein_id="HET2447322.1"
                     /translation="MIKIYTVSSCTSCKKAKTWLNAHQLSYKEQNLGKEGITREELLD
                     ILTKTDNGIASIVSSKNRYAKALGVDIEDLSVNEVLNLIMETPRILKSPILVDEKRLQ
                     VGYKEDDIRAFLPRSVRNVENAEARLRAAL"
BASE COUNT         6740 a         5398 c         4560 g         7629 t
ORIGIN      
        1 tttttcaata tctgagaaga catcattgat atcttgatta ccttcgatgt catgaaccaa
       61 acctttggca cggtagtgag caatgattgg ttctccttga gcaatattaa catccaaacg
      121 acgttttact gtctcaggct tatcatcttc acgttggtag taatcttctt ctttatagtc
      181 aactggtggg ttaaagacct tgtggaaagt ttctccagtt acgcggtgga tgatacggcc
      241 actcaaacgt tccaagaggc tgtcagggtt cacttcaata ttgataatac cttctagttc
      301 aatgccaagt tcagccaatg ttttgtccaa ggcatgagct tgttcaattg tacgtgggta
      361 accatccaat aagaatcctg tttctttaat atcatcttgt gaaaggcgtt cttttacgat
      421 tccatttgta acttcgtcag gaaccaattc acccttgtca atatatgact tagcaagaac
      481 acccatttca gtttgatttg ccattgcagc gcggaacata tcacctgttg agatatgtgc
      541 aacatggaat tgttctacga tttttgctgc ttgagttccc ttacctgcac caggtaagcc
      601 cataatcaaa agattcatga tttgatctcc ttattttatt tttaaataga agcaaaaagt
      661 cttttcaccc ctatttaaaa acaaaataga agaggggaga tccaactctt acaaatgtca
      721 gagtttaaac ctccactccc tcagtattta ctgattcagt aaatactttt attctgttct
      781 gtccatgaaa ccaacatact tacgtttcaa taggtaacct tccaattgct tgattccttc
      841 gatacctgta gagataatga tcaagagact tgttccacca aaggcaacaa catcagaaag
      901 accaaataca tctttagctg caatcggtaa aatggaaatc acaccaagga agagggaacc
      961 aacagttgca agacgacgaa gaagtttaga catatattct tctgtacctt taccaggacg
     1021 aactccatgg atataggcac cactcttttg taggctctct gctgcttttt caggattaat
     1081 ctgtacaaac gtatagaaga atgtaaagag aataatcaac aaagcataca tggcaatacc
     1141 agttggagaa gtagttgcca acatctcttg tgctaccctt acccaagccc aatcatgacc
     1201 tgtggcactc aaaaactgaa gaatagccgc aggcgctgca gtaatcgaac tggcaaagat
     1261 aacagggata actccagcag ggtttacctt taacggaagg taagagctag atggagcacc
     1321 ttgtgcaacc ttagtatatt ggattggaat tttgtattct gcttgttgaa cataagttgt
     1381 aaagtaaata atcaacaata cagtaataat caaaatgatt acgaaaatga tagatgaagt
     1441 gatacggcta cttgggacgt tcacaaagta gtccacatag atgccctgaa tcatctctgg
     1501 aattgaggaa acaatcccgg caaagataat catggaaaca ccgtttccgt atcccttatc
     1561 tgtaatttgc tcacccaacc aagtgacaat catactacca gctgttaaga tgataccaat
     1621 cgtcagaaaa acttgtggag ttaaagcagt tttaatcaat tgagctccag ccaaggtatt
     1681 aaaaccagct gtaatcccga tagattgcac aaaagcgaga actagagcaa tataacgagt
     1741 agcttgattc aattttcttc gacctacttc cccttgttta ccccactcta caaacttggg
     1801 taaaatatcc atttgcaaga gttggacaac aatagaagcg gtgatatagg gactaactcc
     1861 tagggcaaaa atcgaaaagt tttttagggc attccccgac accaagctca acatgtttaa
     1921 gaaggataat ccacttaaag cattcaagct attggcattc acaccaggaa ctgtaatgct
     1981 agttccgata cgaaagacca aaacgataaa aattgtaaat aaaatttttg atcgaacctg
     2041 cttgacttta agagcttctc ttaataattt aaaaaacata ggtcacctct cttagatgac
     2101 ttctactgaa ccacctttag cagtgatagc ttcttcagct gatttagaga atttagctgc
     2161 tttcacagtc aatttcttag tcaactcacc gttaccaaga attttaatac ctgacttttc
     2221 agctttaaca attcctgctt cgataagaac aactggagtt acttcagcac catcttcaaa
     2281 gacgttcaat tggtcaaggt tcacaattgc gtattcttta gcgttgatgt tagtgaatcc
     2341 acgttttgga agacgacgga acaatggagt ttgtccacct tcaaaaccaa ggcgaactcc
     2401 gccaccgcta cgagcttttt gacctttttg accacgacca gatgttttac cgttacctga
     2461 tgaagtacca cgaccaacgc ggttacgtac tttacgagaa ccttctgcag gtttcaattc
     2521 atgaagtttc atttttattt tctcctcttt tgtaaaatgc tagcgccgat aagggagaaa
     2581 aggttgtctc ccccatcaac tcgcctatac gatgtcatca tagatgacta tatctagttt
     2641 taggggatgg tacagtgcac atcccctaaa acttcattag tttacttctt caactgttac
     2701 taagtgagat actgctgtaa tcataccacg gatagcagcg ttatcttctt taataacaga
     2761 gctgttcaat ttgccaagtc caagtgctac aacagtttta cgttgtgatg gaatgcgtcc
     2821 gattggagac ttagtcaaag taattttaat ttgagccatt ttatcccctt tcttatgcca
     2881 aatcagaaac tgaaatacca cgaagggcag caatttcttc agcgcgtttc aattgtttca
     2941 aaccttcaac agttgcacga acaatgttga ttggagtgtt agaaccaagt gatttagatg
     3001 taatatctgc cacacctgcc aattccacaa cggcacgaac tgcaccacca gcggcaactc
     3061 cagaaccttc tacagcaggt ttcaacaata ctttagctcc accgaattct gaaagaactt
     3121 cgtgtgggat tgttgttcca accataggaa cttcgatcaa gtttttctta gcatcatcta
     3181 ctgctttacg gattgcttct ggaacttctt gagctttacc agtaccaaat cctacgcgac
     3241 cattgtggtc accaacaaca acaagagctg cgaaacgaag acgacgtcca cctttaacaa
     3301 cttttgtaac acggttgaca gcaactacgc gttcttctaa ttcaactgca ttgtctttaa
     3361 atgccatttt ctagtgtcct cctattagaa tttcaatccg ttttcacgag ctgcatcagc
     3421 caaagctttc acacgtccgt gatatagata tccaccgcgg tcgaacacca cttctgaaat
     3481 acctttagcg tttgcacgtt ctgcaacgag tttaccgaca gcaacggctt gttcagtttt
     3541 agttcctttt gaaacttctt tatcaagagt tgaagcactt gcgagcgtta cacccgctac
     3601 gtcatcaatc acttgagcgt agatgcctgt attagaacgg aatacgttca aacgtgggcg
     3661 atcagcagtt ccagagagtt ttccgcgaac gcgacggtgg cgtttttggc ggagtttgtt
     3721 tttatctggt tttgaaatca cagttttcac ctctttagtt ttaaatcgtg tgctatgcac
     3781 aaagttggaa aataggttgg tggttgatga tcaaccactc aacattattt acctgtttta
     3841 ccttctttac ggcgaacgaa ttcaccaacg taacggatac ctttaccttt atatggttct
     3901 ggtgaacgaa ggctacgtac gtaagcagct gtttgaccaa ctacttcttt tgaaattccg
     3961 ctaacaacga ttgttgttgg gtttggaagt tcaaaagtaa ttccttctgg agcttcaact
     4021 tcgtctggat gagatttacc aacagccaaa acaagtttag atccttgaag ctgtgcacgg
     4081 taaccaaccc cacgcatttc aagttctttc ttgaatcctt ctgatacacc aacaaccatg
     4141 ttgttcaaaa gggcacgagt agttccgtgg atagttttca tttcttttga atcgtttgga
     4201 cggtgaagag ttatttcagt accttccaca cggatttcaa tatcttttga gaactcacga
     4261 gtaagttctc ctttaggtcc ttttacagtt acaacgttgt cattgttagc gagttcaaca
     4321 ccagcaggca acacgataac tttattacca atacgtgaca tgtttatttt ctcctgttaa
     4381 attgtcaggc cagaacggcc agttttcacg gggttcagat acttatttag ttcaagagct
     4441 gaactgaaca cgctctaaga actgtgcaaa atagataagt tggcttgttt gtaaacaaac
     4501 ttctccaact tcctaatttt gctttgttct ttacgagctt tgtatcttga ttttaccaaa
     4561 cgtaagcgat aacctcacca ccaacattct tttggcgtgc ttctttatca gtaagcaaac
     4621 cttcagaagt tgaaaggatg gcaattccaa gtccgttaag aacttttgga aggtcttcac
     4681 gttttttgta gacacgaagt cctggtttag aaacacgttt caagttagtg ataactttct
     4741 caccatttgg tccgtattta agaaatacac ggatgacgcc ttgtttgtca tcttcaatga
     4801 tttcaacgtt ttttacaaaa ccttcgcgtt taaggatttc agcaatccct tttttgatgt
     4861 ttgatgcagg tacttcaagt acttcgtgtt tagcttggtt agcattacga atacgagtta
     4921 ggaagtctgc gattgggtca gtcataacca ttttgttttt ctcctcttac tagtagtttg
     4981 caagttgcac ttgctagtta atacatgata caaagagcgt aacagcacga gcaaaaatag
     5041 acaatttaat gcagaagcaa tgctccaaag caaattggtc ttttttgcca aagctgtagc
     5101 tcgtgttcaa attggcaagc ccaattgaac ccgggctaaa ctctgtgtga aaaagataaa
     5161 ctttcctaga aactttagtt tcttcgtcaa gtttcctatt tttacttgga gttttgacgc
     5221 tcttgatatc ttaaattacc aagatgcttt tgttacacca ggaatttgac ctttatgcgc
     5281 aagttcgcga aaagcgatac gactcagacc aaatttgcgg taaactgaat gtgggcgccc
     5341 cgtaactcta caacgattat gtaaacgagt cggtgaggcg ttgcgaggta atttagataa
     5401 accttcgtag tcccctgccg cctttaatgc agcacgtttt tcagcataac ggtcaacaat
     5461 tttttggcgt ttagcctctc tagctaccat tgatttttta gccattagat ttacctccta
     5521 tattattttg caaaaggcat tccaaggcct gtaagcaatg cacgtgactc ttcgtcagtg
     5581 ttagcagttg ttacgataac gatgtcaaga ccacgagttt tgtcaacgtc atcgaagttg
     5641 atttctggga agattaattg ttctttcaca ccaagtgtgt agttcccgcg tccatcaaat
     5701 gattttgttg gaacaccgtg gaagtcacgt acacgtggaa gtgaaactga taccaattta
     5761 tccaagaatt cgtacatacg ttcaccacga agggtaactt ttgcaccgat cgcaacacct
     5821 tcacgaagac ggaagccggc gattgatttt ttagctttag tgataagtgg tttttgacct
     5881 gagataagtg ccaattcttc agcagctttt tcaaggcttt tagcgtttga tacagcttca
     5941 ccaacaccca tgttcaaaac aatcttatct actttaggca cagccatcac tgatgagtag
     6001 ttgaattgtt ctgtcaaagc aggaactact tcattaagat atttttcttt taaacgattt
     6061 gccattatac ttctcctttc cttcgtgatt aatcaagcac ttcgcctgat tttttgttgt
     6121 agcgaacttt tttaccgtct acaaatttgt aaccaacacg accagctaca ccatttttgt
     6181 ccaaaacttg aacgtttgat acgtggatag ctgcttcttt ctcgatgata ccaccttgag
     6241 gaagctcgtt agttggacgt tggtgtttct taacaatgtt aacaccttca acgataactt
     6301 tgtttacttt tggaagggca gtaaggacaa cagcttctgt tcccttatct ttaccagcga
     6361 ttacgcgaac tttgtcgcct ttttttacaa acattaggtt tctccttgat ttttcttacg
     6421 cccataaggg caccctagct tgaagctagg ggactagttt gttcctaaaa attaaagtac
     6481 ttctggagca agtgacacga tcttcatgaa gccaccttca cgcaattcac gtgcaactgg
     6541 gccaaagata cgtgttccgc gaggagtttt gtcttcacgg atgataactg ctgcgttttc
     6601 gtcaaatttg atgtatgaac catcagcacg acgagcacct gatttagtac gaacgataac
     6661 tgctttaaca acgtcacctt ttttaaccgc accaccagga gtagcttgtt ttacagatgc
     6721 cacgataaca tcaccgatgt ttgcaaattt acgtcctgaa ccaccaagaa ctttgatagt
     6781 caagatttcg cgagcaccgc tgttgtctgc gactttcaaa cgagtttctg tttgaatcat
     6841 ttcagttttc tcctttcagg tttgattaga tgatgaccgc ttcttcaaca acttctacaa
     6901 gacggaaacg ttttgtagct gaaagcgggc gagtttccat gatacgtacg atatcgcctt
     6961 ctttggcaac attgttttca tcatgagctt tgtatttttt agagtagtta atacgtttac
     7021 catagactgg gtggttacgt tttgtttcaa ctacaactgt gattgtcttg tccattttgt
     7081 cagatacaac acgtccaaca agaactttac gattattgcg ttccattgaa atttctcctt
     7141 ccctagtcta ttatttcgct tcagattgaa ctgttttgat acgagcgatt tgttttttaa
     7201 cttctttcaa gcgagctgtt tgttccaatt gaccagtagc agcttggaaa cgaagttcaa
     7261 acaattcttt tttcaattcg ttttcgcgct tcgcgagttc ttcttgagaa agaccacgaa
     7321 gttctttaac aaattctttt acttcattaa gtttcatgcc ttctccttat tctgcttcac
     7381 gttttacgaa tttacattta actggcaatt tgtggctagc aagtcgaagc gcttcacgtg
     7441 caatctcttc agatacacca gcgatttcga acatcacttt accacgttta actggtgcta
     7501 cccaaccttc aggtgcccct ttaccagatc ccatacgcac accgatagct ttagcagtgt
     7561 atgatttgtg tgggaagatt ttaatccaaa ctttaccacc acgtttcatg taacgagtca
     7621 tggcgatacg agcagcttcg atttggcggt tagtgatcca gtggctagtt gtagcttgaa
     7681 gaccgtattc accgaatgct acttcttttc caccttttgc ttcaccgcgc atttttccac
     7741 ggaactcacg acggtgttta acacgtttag gtactaacat tggttattta cctcctttag
     7801 tgtttttacg agctggaaga acttcaccac ggtagatcca tactttaaca ccaagtttac
     7861 cgtatgtagt atctgcttct tcccaagcgt aatcgatatc tgcacgaagt gtgtgaagcg
     7921 gaacagttcc ttcagagtat ccttcagcac gggcgatatc tgcaccgttc aaacgacctg
     7981 atacttgagt tttgattcct ttagctccag cacgcattgc acgttggatt gcttgttttt
     8041 gtgcacgacg gaaagcaaca cgttgctcca attgacgagc aattccttca cctacaaggt
     8101 gagcatccaa atcaggttgt ttgatttcga tgatgttgat gtgtacttgt tttccagtca
     8161 atttgttaag ttttgcacgg agtgcatcaa cgttagcacc acctttaccg ataaccatac
     8221 ctggtttagc agtgtgaagt gaaacgttaa ctttgtttac tgcgcgttcg atttcaatag
     8281 ttgaaactgc tgcgtcagca agttcttttt gaacgaattt acggattgca agatcttcat
     8341 gaaggtaatc cgcgtattct ttttcagcat accatttggc atcccaatca cggatgatgc
     8401 cgacacgcat accaattgga tgtacttttt gacccacgat tttacctcct tatttttctg
     8461 caacagctac agtgatgtga gctgtacgtt tgttgattgg tgaagctgaa cctttcgcac
     8521 gtggacggaa acgtttcata gttggtcctt cgtttgcgaa tgcttcagat actaccaaat
     8581 tagctttatc caaaccaaag ttgttttcag cgttagctac agctgagttc aaaactttca
     8641 agatgatttc agcagctttg tttggagtga atgtcaagat tgcgattgca tcggctacgc
     8701 ttttaccacg gatgttatca agaacaagac gtgatttacg aggtgaaaca cgtactgtac
     8761 gagccattgc tttagctgaa gtaatttctg ccatttatgt tctccttatt ttctacgtgt
     8821 tttcttgtcg tctgcagcgt gacctttgta agtacgagtt ggtgcaaatt caccaagttt
     8881 gtggcctacc atgtcttctt ggatgtaaac aggtacgtgt ttacgtccgt cataaactgc
     8941 aatagtgtaa ccaatgaaac ttgggaagat cgttgaacga cgtgaccaag ttttaataac
     9001 ttttttcttt tcgtcgttag cttgagcttc aacttttttc atcaaatgct catcgacgaa
     9061 aggtcctttt ttaagactgc gtcccatttt tatattttct cctttaaatg ttgtaccaca
     9121 gcggcttgca ctcctatgga gcgctaccga gctggcggat ttactagttg cttaagcgac
     9181 tagtttaata ttatttctcg ttgcgacgac gaacgataag tttgtcagat ttcgctttct
     9241 tgttacgagt tttaagacca agagcaggtt tgccccatgg agtagatggt gctttacgac
     9301 caactggtgc tttaccttca ccaccaccgt gtgggtgatc gttagggttc attacagaac
     9361 cacgaactgt tgggcggata cctttccaac ggctacgtcc tgctttacca aggtttacaa
     9421 gtccatgttg ttcgtttccg acaacaccaa ctgtagcacg gcaagttcca agaatcatac
     9481 gaacttcacc tgattgaaga cgaacaagaa catatttacc ttcagaaccc aatacttgag
     9541 cagatgcacc agcagcacgt accaattcac caccacgacc tggtttcaac tcgatgttgt
     9601 gaatcaaagt accaactggg atgttagcaa gtggaagagc gtttccgact ttgatatctg
     9661 cttctggacc tgaaacgata cgttgaccta cttcaagacc ttttggagcg atgatgtatg
     9721 ctttcacacc gtcagtgtag tgtacaagag cgatgtttgc agaacggttt ggatcgtact
     9781 cgattgtttt aacaactgct tcaacgttgt ctttattacg tttgaagtca accaaacggt
     9841 aaaaacgttt gtgtccacca ccttggtgac gaactgtgat acgaccgttg ttgttacgac
     9901 cagccttgct cttcaatgca acaagcaatg atttttcagg agtgcttgtt gtgatttcag
     9961 cgaaatccaa agaagtcata ttacggcgac cgtttgttgt tggtttataa acacgaattc
    10021 ccacgatatt tcctccttag attattcagc ttcagcagca aacaactcga ttgctttaga
    10081 atcagctgta agtgtgatga tagctttttt agttttgtta gtaaaaccag tgtaacgtcc
    10141 aacacgttta gcttttggtt ttacgttgat tgtgttaaca ttggcaactt taacaccttc
    10201 gaaagcagct tcaacagctt gcttgatcaa aagtttgtgt gcacgagtgt caacttcaaa
    10261 tacatatttt cctgcttcaa gttgagccat tgagctttca gtgatgacag gttttttgat
    10321 aacatcatac aaattcatta tgcaagaacc tcctcgattt tagagatagc tgcttgtgtg
    10381 acaagaagtt tgtcgctatt tgcgatgtca agaacacttg cagttgtagc agttgcaact
    10441 ttcacgtttg gaaggttacg agctgaaaga gctgcgaatt catttccttc ttcaaggata
    10501 acaagaactt tagaatcgat gctcaatgct gcaagaactt ttgcaaattc agcagttttt
    10561 ggagctgtaa atgaaagagc gtctacagct acgaatttgt tttcagcaac tttttcagag
    10621 taaactgatt taagagctag gcgacgaact ttttgtggaa gtttgtagcc gtatgaacgt
    10681 ggagttggtc cgaagacaac accaccacca cgccattgtg gtgagcggat agaaccttga
    10741 cgagcacgtc cagttccttt ttgacgccat ggtttgcgtc caccacctga tactgcagag
    10801 cggtttttaa cagcgtgtgt tccttgacga aggcttgcgc gttggctgat gattacatca
    10861 aacacaactg attcatttgg ttcgatacca aatactgcat cgctaagaac aacttggcca
    10921 gcttctttac cagtttggtc aaataatgtt acgtttgcca ttgtgactga tttccccttt
    10981 ctttattatt taccagcttt aactgctgat ttgatagtga taagagattt cttagcacct
    11041 ggtacgttac ctttgataag gataacgttc ttttctggaa caacttgtac aacttcaagg
    11101 ttttgaattg ttacgcggtc gccacccata cgccctgcaa ggtttttacc tttgaatacg
    11161 cggttaggtg caacaggtcc catagaacct ggacgacggt ggtaacgaga accgtgagcc
    11221 attggtccac gtgattgtcc gtggcgtttg ataacacctt ggaaaccttt acctttagaa
    11281 gtaccagtta cgtcaacaac gtctccagct gcgaatgttt caactgtaat ttcagcacca
    11341 acttccaagc cttcaacgtt tttgaattca cgaatgaagc gcttaggagc cgtgttagct
    11401 ttcgctacat gtcctttagc aggtttgttg ctcaatactt cgcgtttgtc atcgaaacca
    11461 acttggatag cgttgtatcc gtctgtttca acagttttaa cttgaagaac aacgtttgga
    11521 gttgcttcaa taactgttac agggatcaat tcgccagctt cagtgaagat ttgagtcatt
    11581 cccacttttt tccctaagat tccttttgtc atgagaaaat agttcctttt ctatattttt
    11641 attcaaaaag tttttaacga gcgtttttta tgctcaagtc taagatacaa agggcgtcaa
    11701 actcaacgtg aaaataggaa actgacacag tgtctagcag acgcgaggaa gtttatcttt
    11761 ttcacaccga gtttagcccg tgttcaatta gattgaaaca ccagcctctg ctcttttata
    11821 ttttagatta aagtttgatt tctacgttta caccacttgg aagatccaat ttcatcaagg
    11881 catcaactgt tttttgagtt gggttaacga tatcgatcaa acgtttgtgt gtacgcattt
    11941 caaattgttc gcgagagtct ttgtatttgt gagtcgcacg aatgattgtg tagaggctac
    12001 gttcagttgg aagtgggatt ggacccgcaa cttgtgcacc tgtacgagta gctgattcta
    12061 cgatttttgc agccgctgtg tcaagcgtac ggtgttcgta agctttcaaa cggatacgga
    12121 tttttttgtt tgccatcttt ttctcctttt cgtctattta agataatagg ctagctccac
    12181 aagaaaaccg acgcggtgtt gcgtggcaat gcaaccgagc gtgtcgcaac ctcttgcatc
    12241 aaaactaagg ctgtaattta cagcaccata atagaataac acaaatcccc tgcgattgca
    12301 agggatttgt taggtttttt cgttttttgg ggatgaaact gttttcctac tttttctttc
    12361 taaaattagg gattttcttc tatatttctt ctatacataa gttaagtcct cttgacatca
    12421 aatttatctt ctgattggtc cactaagata tccgccttag actcagtttc tttatagtat
    12481 cgcagatact gctcccgtct catctgatgg ctagccaata taaaggatgc atcgcgattt
    12541 ctcacagtcg tatctctagc aaggcgtcgc tttaattcgg tctcctcatc cgtgtagaaa
    12601 cagatggttt tttcaaagag ttccttgggt agaaagccaa cagacatccc ttcgacaatc
    12661 aaaattggtt tggctccaga caagacctca ctagccttcc aaggttcttc aattgtcaag
    12721 acatccatac ccgcctgcaa ggcaaggata tctctctgca aactctccag ttcatgcgcc
    12781 actggcagac tggctgtcac cttttgattc ggcgcgtcct tgggtactac caaatagcgt
    12841 ccggaggtga tatagggatc tgtttctagc aaatttactg tagtagaatc taaagcttgg
    12901 tacaattcct gtgcaaaggt tgatttacct gaagctccat gaccgtatat tcccagtgtc
    12961 ctgactttcc ccgtctcgat ctctgagact agttggtcta ctaagtcttt tttcttcatt
    13021 ctctcttcac ctgttcatag atttcttttc cgtcattgag cttgtcccaa atcactactt
    13081 gcccactttt gagcgatttt tgcacatcga taattcgttg gttagacgaa cctcgaaact
    13141 ggagcataag atttctctta gttcgatcat atcttccatc gacaagaatg tcaatcagtg
    13201 acaagagttc cagtttatct ggagtttcca acatcatttc ttcccaagtg tagcccgtcc
    13261 aggaccagat gtccttgtct ggcaattcct tccgaatccg cttaacaagt ggcaagagaa
    13321 tcccagtatt aagaaaaggc tcccctccta gtaaggttaa cccctgaaca taaggctggg
    13381 caagatctgc cataatctgt tcttccaact cagctgtata gggaatgcct gcattgaagg
    13441 accaggtcgc tacattataa cacccctcgc agtgaaacat acagcctgct acatagagag
    13501 agttacgcac gccttcgcca tcaacaaagt taaaggcctt gtagtcaatg atacgacctt
    13561 gactaagttc ctcgcttttc cattcttgtg gttttggatt attcattcgc tacctctatc
    13621 caataacgct cgactccatt gcgagcatcc tcaaatattc caccatttgc tagaatgact
    13681 gctctgctag caggattatt cacgctacag gtcaccagag ctttcttgat gttcttttcc
    13741 ttagcaactt gcaagccctg acggagagtc tcttttgcat aacccttgcc tctttcagat
    13801 ggacggatgg agtagccaat gtggccagca taattcagta acccctcatt cagtctcaat
    13861 cgcagattca aaaatcctag agcacaacct gattcaccaa acaatacgaa ctgtatcgat
    13921 ggaacgcgat tttcaggtag ccatattccc atttctttat tacggttacc ttctagccac
    13981 tcctcgtaag aaaaatcctc aacatcccaa aatcctccat catgggctga ttggctcttt
    14041 tcaaactctg tcatcatatc taaaacagct ttcttatccg ctaatcttgg tctgcgtaat
    14101 tccatcctta cctcccacta tgagaaaagc gagagctggc tctcactttt attttttctt
    14161 gttcttgttt aaaaattgtt ctctgaagct aagcaagcgt tctttcttac cagctccacc
    14221 tttagagtgt ttctcgtgat aacgggtcac ttgtgcgcgc cccttatcgt ctagttgata
    14281 ttttcccatt tcatttcttt ctaatttgtt acttgatgcc cagctatttt aatcgttgaa
    14341 ccattcatat gtttgacacg cgcagcgatt tccttgtgac gcccgttgac catcggtctt
    14401 gcttgaggat tacctaggta gccacaagtt cgcttcacca catctactgt tttagggtcg
    14461 ctattgccac agtttggaca agcaaaccct ctctcagttg gttcaaaatc cccttcaaag
    14521 tcacacttgt agcaacggtc aatcggagta ttggtgccta gatagcctac acggtcataa
    14581 gcataatccc agacagcttc caaggccttt ggattttgct gaaggactgg atactcacaa
    14641 taatggatga aaccacctga cgcacctgct tctggataga ctttctcaaa gtccaatttt
    14701 tcaaacggtg ttggattttt acgaacatcg tagtggaaag agttggtgta gtattccttg
    14761 tctgtgatat caggaataga gccaaacttg tctatatcta gtcggcagaa acggtctgtc
    14821 agactttcgg atggtgttga gtagatagag aaatggtagc catattggtc tgaccactct
    14881 tctacacggc gtttcatatc gtgaatgatg tctagcgtga attccttagc atctggatta
    14941 ctttcccagc tgttaccaaa gaaaactgtc gctacttcat acaagccgat atagcccagc
    15001 gaaacggtcg cacgacaatt cttaaagagc tggtcaacac tttcttcttt acctagacga
    15061 tggccaaaag caccgtactg ataaaggata ggagcattcg ctggtgtcgc ctctttagtg
    15121 cgttcgacac ggtaaacaag agcatcttct gcgatattca ttcgctcgtt gaagatttcc
    15181 cagaacttat tcatatcacc ttcagactca agagcaatac gaggcagatt aaccgtcaca
    15241 acacccagat tcatgcgacc tgaattgact tctacaccat tttcatcctt ccatccttgg
    15301 aggaaagaac ggcaacccat aggcaccttg aaggatcctg tcaagtcaac aatcttatcg
    15361 taagataaaa catctggata catccgtttg gttgcacact caagagccaa ctgcttgatg
    15421 tcgtagttgg gagttccttc ctctaaatta aggcctcttt tcagagtgaa aataagttta
    15481 ggaaagatag ccgtacggtg ttctgaacca agacccttga tgcgaatgtt taaaatagct
    15541 ttttgaattt ctcgttcaaa acgactggtt cccagaccaa aacctagcga agtaaaaggt
    15601 gtttgtccat ttgaagtgaa gagagtattg atttcatact caagagattg catggcatcg
    15661 tagatgtcct tttgcgtttt cttccaagcg taatcttccc gtttttcagg caatacccac
    15721 tcttctgcat ctttgagatg tttttgatag ttcttctctg cataaggcgc caaaatttca
    15781 tcgatacggt cagctgaaca gccaccgtac tggctagaag caacgttggc aatgatttga
    15841 gaaatctgtg ctgtcgcagt ctggatagac ttgggactct ctacctctgc atttccaatc
    15901 ttaaaaccat tttccaacat acccttaaaa tcaatcaaac agcagttggt cataggggta
    15961 tagggactgt agtccaaatc gtgatagtgg atatccccct tttggtgggc attggctacg
    16021 tgcttaggaa gcatttgcag tccgattgat ttcccaacaa tccctgctgt caaatcacgc
    16081 tgagtgttaa agacatcact gtctttatta gcattttcat tgacaactgt ctggtctttg
    16141 ttgagaagtt tatgaatact aaagttgata tccgtcgctt ttgagcgctc aaaatccctc
    16201 tgtgtccgat aagtaatata ctcctcagcc agcgcatatt ctttggcttc aaggagttca
    16261 tgttctacga tattttgaat ttcgtaaatc ttaattccct gtggaaagcg actatgaatt
    16321 tctgtaataa ttctctcagt cagatcattg aggcgttttt caaccagggg tgtcacatcc
    16381 ataaccttgt cagctgcctt gtggagagcc ttgtcaatct tgtccacatc aaatacaaca
    16441 cgtctcccat ctcgtttctc gacgaagaga gttggcaaaa ttgtaatttt ttcttctagt
    16501 gcaatcatat gcatgctctt ttctaaaatg ttctttctaa aaagtattat accactctaa
    16561 aaagaaaaat caatatcttg tgttaaaaat cctaaaattt ttaaaaatac acaagatatt
    16621 gatttggtta tttaatttta tagactttaa actctgagta atcagtcttt acttgttggt
    16681 aattttcttt taaaagtgtt tccacttcag accagactac caccttgtca tttaccacaa
    16741 tcaccttagg ttgtttttct ttcaagtcat taagtaactt attacgattt tcctcagttg
    16801 ctgtatagtg caacggggac aaaatcgccg atggcgacaa gcgctcactc ttacgataaa
    16861 gagtcgcagt atcatcccat gcatagatag catcttccgt atttgtctcc tcttttacca
    16921 aatcagcaag acgattacgt tcttgataag gtactggata aaggacaaac ttcatcaaaa
    16981 aaggaacaga caaaagatag acaaacccaa aaactagcag atatagattt cctttgaaga
    17041 aacgactcca taggctaact ggcgtttctc ttcggcttct tctagcacta cgccccctct
    17101 gttgactctt gatattggtt accaataaaa gtaggaaaac agggaagacg accatcaaat
    17161 aagaagcgtg cagaggctct tgtgaaaaga aaagtaaaat caaacctaaa attaccacaa
    17221 gacttgcagg aaccgaaatg acgtatagtt taaagggttt ggattgaaag agacctaaaa
    17281 agatacaaac cacaaatccc aaaccaaggg acaacaagcc ataaaaaaac atattctcta
    17341 aaattttaga agtaaaatca aagcgaatac tgtcaatagg ataacgaata ccactaatcg
    17401 catccccaaa acttcctgtt gcagcactat agtaggcagt tggataaaag acaagtgaaa
    17461 aacctaaagc cactgcaaga aactgataaa acccatgcgc aaagcgtcta tgcccaaggt
    17521 taaagaccaa caagcctaaa ctcactacag caataaacag gagtgatgat aagggagcaa
    17581 agaaaaatcc gcctgccaaa gctaacccaa tccgtacaaa tcccttatca tggcttggat
    17641 tgcttaggta agccgcaact aaactaaagg ctgcgaataa gaaaggaagc gctaaaagag
    17701 tcgcatagcc tccaccaaaa gcaagacctg taactagcat gtaaaaaata gtcaccagat
    17761 gtccagcttg gtctccttgc tctgtcaagg tgtccgctga tctaaaaagg aaaaatcctc
    17821 ctgctaccaa ggctaaccac tcaaagatgg caaagaaaaa tccgccctga ctcacgtaag
    17881 tcagcaaata ataaagcaaa ccttgacttc cataatagtc gctgtaaatc ttccctgtct
    17941 gatgaagcgc ccaacctgca taaaaatcct gcacttcttg tgcactcatt aagtcgagta
    18001 atagcggtac tcctagagtt atccccgtta caagcgtact ccatagtaaa attttcacca
    18061 aaggaagacg acttgattca cgatgatgcg attcttgctc gatttggtat tctagaggtt
    18121 cacgattctc cttatgaact tcttctactc taccatacac actcatatcg tttctcctgt
    18181 tcaatttatc tgtcttagta tatcaaaaag tcctaggatt gtcagcttgc gatggctgtt
    18241 tgagtgattt tttgcatagt ttcacaaagg tttcaatttc ccgaaagcgg tgtaaatgtg
    18301 tctgtttgaa ctcaatcata tcattcactt cttccttagt tagcatgaat tcccctcctc
    18361 tttctttcta ttcgtaaaag acaagaaaaa taggtcgggt ttgtatccta agttctagat
    18421 ttcttataag ataggggcga atagctgggc gatttctttt acaagctttt gataccagct
    18481 cgttttgata gaatgaggat agacttcctg agaatctgca aatatatttc gaaaatctcg
    18541 ggcgatttcc cttatagaag gagttttata gagtaagact gcattttcat aatggtgtac
    18601 caagctccgg tagtcgagat tgattgtccc caccaccgca aaatcttcgt ctaccaacat
    18661 ctgcttacta tgaataaaac ctggactata ctcataaatc cgaacaccag cagaaagaag
    18721 gtcgggataa gctcctctcg tgactaactg aatgaacttc ttatctggta tgtaaggggt
    18781 gataattcga acatcgaccc ctctcatagc tgcatttttg attgtctctg ttaaatcata
    18841 atctataatc aaataaggtg tcgtaatata gaccgattcc gttgcttgat tgattaaact
    18901 ctgataaact tttttcccta cctgcgctcg aaaaattggc ttgggtccac ttccgtatgg
    18961 aatggttaaa ccgtcactcg ggatagaatg attttctaaa tgatattgat caaaatcact
    19021 aatttctcct cgattaatgt accaagtggt caaaaataag cgtgtcaggg cttttactgc
    19081 tagtccgtct aagcgaattc cactatcctt ccaataacca aatctctcga cgtggttaat
    19141 gtactcatct gccagattga ccccaccagt ataggctatc tgaccatcaa caatcaatat
    19201 ttttctatga tctctgttat tataagccac tgtcaaacga ggaataactt tattgaattt
    19261 atgggcctcg atgcccagct gacgaagtcg atgtgcataa tctcctgtta aagtagccat
    19321 acagccgata tcatcataga gcatcttaac ctctacaccc tgagctacct tttgctctag
    19381 tatatctagt atgcgattcc acatcaaacc ttcttctata atgtaatatt ccaagaaaat
    19441 aaatttctca gcctttttaa gatcttctac catctttttc cacatagctt ctccgttagg
    19501 aaaaaatgta gaggcagttt gatcatagat gtcagcattg gtatccatac tcaataagga
    19561 cttgatgact ccataagctg ccttgtcact ttcttttaat ttctctttta gtagctggct
    19621 atttgcttct tggaaatgca tagagcctag cttcttcagt tgtttgattt cttttttgga
    19681 caatcgcctt tcaccaaaca tcagatagag taagggacca aatactggca caaaggctac
    19741 taacaaccag gttaccttat tctcaggagt cgtattacgg ttgactatcg aaatgattgt
    19801 gatgatactc agtagaatga ggacagtaat ccataaaatg ggagccatgc gtcctaaata
    19861 aagaaagaga ccaaaaacaa gacaaagttc aagtagcata atcgaaagac taaagccata
    19921 cttggacatc aataattgaa atttcctata tttcatatcc cctccttgat agtttgaatg
    19981 ctaaaaacaa gtaattgata ctagtataac gcaggtattc ggtagaaggc aagtatttat
    20041 gattattttc taggtaaaag taaaaaggct gaaaaatcca gccctttcta cttgcatagt
    20101 cttatttagt taaaacgatt tggtccgatg ggtctctatc catatcatct acgacgattt
    20161 gattaccgtt tacagtgtaa attttgacat catcgccaat aatcatgcgt tgatttgctg
    20221 aatcaaatgt aacctgtttg actttctgat ccccgtcaga ttcgagctca gtccatgtac
    20281 cagtcgttcc agttaccact aaagtgatac ggtctccgtc atcctgacca gtataagtcc
    20341 catcaatatc ggtcggttga gcaacaggtt ggttttgtac tggagccgct tgattttggt
    20401 tacctcctgc atttgcagta ttggtattct gttgagcagg ttgttgagca ggctgttgga
    20461 cctgctgctg agcaacaggc tgttgaacct gttgagctct ttgtgaacaa gctactaaga
    20521 gactaaaact tgctagagaa gcaagagaaa gtgtgaatct ttttaatttc atgatgaatt
    20581 tcctttctgc taccaattta gagaaatttt ctctaaccag caattcccct agtataacaa
    20641 gttcaaacaa gggggtcaat ttatctgctc acggtccagc aggtagcccc gtacttctga
    20701 gataaaatag agagaccctg taacgaacag caagtcttga gcgtctgccc tttcttcgaa
    20761 actgctgata aattctcggc aagaagaaac tatatcgtaa cctgtcacat ccctttcgtc
    20821 caaagccccc tgatagtcaa agccggtcac cttgagttcc acctgaggca atttttcagt
    20881 caggtaacct aacatccctt gataatcctt ccgtttcaag gctccaaaaa ggatttgagg
    20941 tcgatagcct tcctgctctt tttctttgat aaactcaacc aagcgagtca aggcagggag
    21001 gttatgagca ccatccaagt aaatctgtgg gcgaatacgc tccaagcgac cagcccaatg
    21061 ggtctgttcc aaggcctttc ttacagcctg ttcatcaaca gcttcctttc cttctcccat
    21121 aaaaagaaga aaagtttgca acgccaaggc tgcattctcc tgctgataga ctccttctaa
    21181 gcctatgttc agctgtgaaa aatttagtaa agagcttgaa aaatcaccat tcagcattaa
    21241 aaaatcttga cctgcctgat aaaggttaac agctaaagat tcggcttttt tctgacagac
    21301 aagcctagct tctggaggca atttcgcaat cactgccttc ttaccagcct tgaaaatacc
    21361 agctttctgc tctgcaattg cttctagact atcacccaag gtttcttgat ggtcaagccc
    21421 aatggaggtg atgacagcaa gctctccagt taccacattg gtcgtgtcaa gtaagccacc
    21481 aattcccact tctaataaaa ccaaatccac ctcttgctcc ctaaaataaa gaaaagcaac
    21541 caaggtcagc atttcaaaaa aggacaactg gtcaggagtt tgcagaagcg ttttctccat
    21601 ctccttgacc tgatcagcca aacggataaa gtctgcgtct gctataggtt gcccattaat
    21661 gcagattcgg tcattgatag agacgatatg aggggaggta aaggtcgcaa cttttttgcc
    21721 atgccccata aataattccc tcataaaagc aatggtagat cctttcccat tagtccctgt
    21781 tacgtggata atagggtaag actgctcagg atttcctaac aaatccaccg cttgctgtat
    21841 tcggcccaaa cctgatcgaa aattcaaacc aatccgacta tgaagccatt cttctacttc
    21901 aaacatacac atctccttga caaaagtcca atcaattatc gcattaaagt atggttacta
    21961 ataaaaacaa ggccaggatt ttcgtcccga cctcttacct ggttagctaa taactagcca
    22021 ctatgaatgt gaatatgggc taaaaacatc cactagatgt tccaactctt ccccatttct
    22081 gggagttggg ctgatacagt ctcccagact gtatcactcc tccataaagc tgttgaagac
    22141 ttcttcaatc atgttccatt cgtcttctga gtcttctggg attggttgca attcgccttc
    22201 tgttccatct tcattttcaa tgaatgagta agcttggatt tcaacttgtc cgtcttcgtc
    22261 ttcttctgcg ttaactggta ctagaagaac atagttttta ccaaattctt cttttccatc
    22321 aattgtcaaa aggatttcaa acaaggtttc atttccttgc tcatctacta gtgtgattag
    22381 ttcacgttct tcgtggtcgt ggttatgatc gtgtgacata gcctctcctt tatattaaaa
    22441 ttttctatct aaataatttt gtaaaatcag ctgagctgct aacttatcaa tgactttctt
    22501 gcgcttattg cgactgatat ctgcttgttc aatcaacatg cgctcagcag ccactgttgt
    22561 caagcgttca tcctgatagt ctaatggtaa accaaaaaac tcttctagct ttgctccgta
    22621 ggcttgacta gcttctacgc gcggtccact tgtattgttc atgtttttag gcaagcccac
    22681 tacaaatcgt tccaccttgt aagtatcaac caattcctta acgcggtcaa aaccaaattg
    22741 gccttgttct tcatttatct ggatgatttc aagcccttga gctgtaaaac caagcggatc
    22801 gctaatcgcc acccctaccg tttttgaacc gacgtccaat cccataattc tcataggtta
    22861 tagatcgact ccttgtcctt tgaggtagta gcgaaccaat tcctcaacga tttcatcacg
    22921 ctcatactta cggatttgat ttcgtgcatt attataacga ggaacgtagg cagggtctcc
    22981 actcaatacg taacctacga tttggttaat tgggttgtaa cccttatcgt tcaacgaagc
    23041 ataaacatct gtcaaagttt cgctaatttc ttttttattg gaatcgtcca atttaaaacg
    23101 tactgtttct tcagtaaatc ccattctaac accctctttc cttagaatag taccattata
    23161 gcataattcc ttaccttcta caattcaggc agtctattta tttggatttt ctattgttct
    23221 gtcgcgccat ttgccaatct atctgaaata tatttgcttg gttcattttt caaaagattt
    23281 tccaaaccaa tattcttcag atgttccaac tgggaagcct tcttgacatc cagaacttga
    23341 aaatcaaaac tagtcgttgt ttgaagttcc gttgcgctca atagttttgt ttcaagtttg
    23401 aaacctgcca atttacgagc ttcaatgata gacttatcct tctcctccgc ttcaagaaga
    23461 gctttttgag tttcctccac tccatgttgg tcaatataag tcttcaactc atcagagact
    23521 ggacgttttt gttggatagt tagactcaaa aaagtcttgt ccttgtatgt aatggtttgt
    23581 gtctgctggc taccatcatc tgacttgggc aagaccaaag tcttagttac aactgtattc
    23641 ttctcagcat tttcaataac tggcaatgcc gactgaagcg tatctttttc tgtttttgta
    23701 gctggtccag tttctttttt ctgtccgcaa ccaaccagga caaaaaggaa agctagacta
    23761 acaagaacta tttttttcat ttctttcttc tttctttttg aaattaaaat agaataagac
    23821 tgggaagtgc tcccagcctt gatgtttata gagctgcacg caaacgtgct tctgcatttt
    23881 ctacattacg gacagagcgt ggtaggaagg cacgaatatc gtcttccttg tagccaactt
    23941 gcaggcgttt ttcatctaca aggattgggc tctttaaaat tctcggtgtt tccataatca
    24001 gattgagaac ttcattgaca ctcaaatctt caatatccac tccaagggct ttggcatagc
    24061 gatttttaga cgaaacgatg ctggctattc cgttatctgt tttggttaga atatccagta
    24121 attcttctct cgtaattcct tctttaccaa ggttttgttc tttataactt aactggtggg
    24181 cattgagcca ggtttttgct tttttacagc tagtacaact tgagactgta taaattttaa
    24241 tcatgtacct acccctttcg ctacatgtta ctatcagttt agtctattat accataaaaa
    24301 acatccgact tgcgacctat ttttaat
//
LOCUS       DAVBBO010000030        23482 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ST1
            SAMEA2066453-rid20184263.denovo.030, whole genome shotgun sequence.
ACCESSION   DAVBBO010000030 DAVBBO010000000
VERSION     DAVBBO010000030.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2066453
            Sequence Read Archive: ERR351777
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 23482)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 23482)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980402.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980402.1
            Genome Coverage       :: 176x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:17:33
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,141
            CDSs (total)                      :: 2,104
            Genes (coding)                    :: 1,953
            CDSs (with protein)               :: 1,953
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 16S)
            partial rRNAs                     :: 1 (23S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 151
            CDSs (without protein)            :: 151
            Pseudo Genes (ambiguous residues) :: 0 of 151
            Pseudo Genes (frameshifted)       :: 73 of 151
            Pseudo Genes (incomplete)         :: 76 of 151
            Pseudo Genes (internal stop)      :: 40 of 151
            Pseudo Genes (multiple problems)  :: 32 of 151
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..23482
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2066453-rid20184263.denovo.030"
                     /strain="ST1"
                     /db_xref="taxon:1313"
     gene            complement(1..319)
                     /locus_tag="VQU30_001208"
                     /pseudo
     CDS             complement(1..319)
                     /locus_tag="VQU30_001208"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007897432.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus and C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(395..796)
                     /locus_tag="VQU30_001209"
     CDS             complement(395..796)
                     /locus_tag="VQU30_001209"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001826718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HET2447323.1"
                     /translation="MDSASIIAHTIHQKFNLKVPNYRQEEDWARMGLPITRKEIANWH
                     IKASQYYLESLYNLLREKLLEQPLLHADETSYRVLESDSQLTYYWTFLSGKSEKQGIT
                     LYHHDQCRSGSVVQEFLGDYSGYVHCDMLRQ"
     gene            complement(804..1109)
                     /locus_tag="VQU30_001210"
     CDS             complement(804..1109)
                     /locus_tag="VQU30_001210"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001810009.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS66 family transposase zinc-finger binding
                     domain-containing protein"
                     /protein_id="HET2447324.1"
                     /translation="MFPVETEEITYKRKKSKGKRQALLAQFDSEEVHHQVEESICSDC
                     QGDLKEIGATLQRQELVFIPAQLKRIDHIQHAYKCQACSDKNPSDKIVKAPIPKAPL"
     gene            complement(1096..1290)
                     /locus_tag="VQU30_001211"
     CDS             complement(1096..1290)
                     /locus_tag="VQU30_001211"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000691852.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HET2447325.1"
                     /translation="MKIIQQQSATIDSLTNALALLREQVAYLTQKLYGKSSEKSVCPS
                     GQLNLFEEESPSEKDGDVPS"
     gene            complement(1366..1706)
                     /gene="tnpB"
                     /locus_tag="VQU30_001212"
                     /pseudo
     CDS             complement(1366..1706)
                     /gene="tnpB"
                     /locus_tag="VQU30_001212"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001846105.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS66 family insertion sequence element accessory
                     protein TnpB"
     gene            complement(1687..1872)
                     /locus_tag="VQU30_001213"
     CDS             complement(1687..1872)
                     /locus_tag="VQU30_001213"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001136123.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2447326.1"
                     /translation="MPQPIVPVEIPQSRPFDSKKRNDILLKIRIGKLEVSFFQSLNLE
                     MVEQLLDKVLLYDNSSI"
     gene            complement(2176..3738)
                     /gene="guaA"
                     /locus_tag="VQU30_001214"
     CDS             complement(2176..3738)
                     /gene="guaA"
                     /locus_tag="VQU30_001214"
                     /EC_number="6.3.5.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000065723.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine-hydrolyzing GMP synthase"
                     /protein_id="HET2447327.1"
                     /translation="MSNISTDLQDVEKIIVLDYGSQYNQLISRRIREIGVFSELKSHK
                     ISAAEVREVNPVGIILSGGPNSVYEDGSFDIDPEIFELGIPILGICYGMQLLTHKLGG
                     KVVPAGDAGNREYGQSTLTHTPSALFESTPDEQTVLMSHGDAVTEIPADFVRTGTSAD
                     CPYAAIENPDKHIYGIQFHPEVRHSVYGNDILRNFALNICKAKGDWSMDNFIDMQIKK
                     IRETVGDKRVLLGLSGGVDSSVVGVLLQKAIGDQLICIFVDHGLLRKGEADQVMDMLG
                     GKFGLNIVKADAAKRFLDKLAGVSDPEQKRKIIGNEFVYVFDDEASKLKDVKFLAQGT
                     LYTDVIESGTDTAQTIKSHHNVGGLPEDMQFELIEPLNTLYKDEVRALGTELGMPDHI
                     VWRQPFPGPGLAIRVMGEITEEKLETVRESDAILREEIAKAGLDRDIWQYFTVNTGVR
                     SVGVMGDGRTYDYTIAIRAITSIDGMTADFAKIPWEVLQKISVRIVNEVDHVNRIVYD
                     ITSKPPATVEWE"
     gene            3880..4578
                     /locus_tag="VQU30_001215"
     CDS             3880..4578
                     /locus_tag="VQU30_001215"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000936186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HET2447328.1"
                     /translation="MLPAYMKIHDQIKKDIDEHRWAIGERLPSERDLAEQFAVSRMTL
                     RQAVSLLVEEGVLERRVGSGTFVSSTRVQEKMRGTTSFTEIVKSQGKVPSSQLISYKK
                     TIPNEQEVAKLGIFPTDNIIRMERVRYADQVPLVYEVASIPEKFIKDFKKEEITSHFF
                     QTLQKHGYRIGKSQQTIYARLAKEKIAHYLEVEKGHAILGLTQVSYLEDGTAFEYVKS
                     QYVGERFEFYLENN"
     gene            complement(4621..5517)
                     /locus_tag="VQU30_001216"
     CDS             complement(4621..5517)
                     /locus_tag="VQU30_001216"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000071673.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EamA family transporter"
                     /protein_id="HET2447329.1"
                     /translation="MSNSLKGTLLTVVAGIAWGLSGTSGQYLMAHGISALVLTNLRLL
                     IAGGILMLLAYATAKDKILVFLKDRKSLLSLLIFALIGLFLNQFAYLSAIQETNAGTA
                     TVLQYVCPVGILIYSCIKDRVAPTLGEIVSIIFAIGGTFLIATHGQLDQLSMTPAGLF
                     WGLFSALTYALYIILPIALIKKWGSSLLIGVGMVIAGLVALPFTGVLQADIPTSLDFL
                     LAFAGIILIGTVFAYTAFLKGASLIGPVKSSLLASIEPISAIFFAFLIMNEQFYPIDF
                     LGMAMILFAVTLISLKDLFLEK"
     gene            complement(5526..6461)
                     /locus_tag="VQU30_001217"
     CDS             complement(5526..6461)
                     /locus_tag="VQU30_001217"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000872223.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-lactamase family protein"
                     /protein_id="HET2447330.1"
                     /translation="MKWTKIIKKIEEQIEAGIYPGASFAYFKDNQWTEFYLGQSDPEH
                     GLQTEAGLVYDLASVSKVVGVGTVCTFLWEIGQLDIDRLVIDFLPESDYPDITIRQLL
                     THATDLDPFIPNRDLLTAPELKEAMFHLNRRSQPAFLYSDVHFLLLGFILERIFNQDL
                     DVILKDQVWKPWGMTETKFGPVELAVPTVRGVEAGIVHDPKARLLGRHAGSAGLFSTI
                     KDLQIFLEHYLADDFARDLNQNFSPLDDKERSLAWNLEGDWLDHTGYTGTFIMWNRQK
                     QEATIFLSNRTYEKDERAQWILDRNQVMNLIRKEE"
     gene            complement(6458..7183)
                     /locus_tag="VQU30_001218"
     CDS             complement(6458..7183)
                     /locus_tag="VQU30_001218"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001102210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CppA family protein"
                     /protein_id="HET2447331.1"
                     /translation="MNVNQIVRIIPTLKANNRKLNETFYIETLGMKALLEESAFLSLG
                     DQTGLEKLVLEEAPSMRTRKVEGRKKLARLIVKVENPLEIEGILSKTDSIHRLYKGQN
                     GYAFEIFSPEDDLILIHAEDDRASLVEVGEKPEFQTDLASISLSKFEISMELHLPTDI
                     ESFLESSEIGASLDFIPAQGQDLTVDNTVTWDLSMLKFLVNELDIASLRQKFESTEYF
                     IPKSEKFFLGKDRNNVELWFEEV"
     gene            complement(7267..7902)
                     /locus_tag="VQU30_001219"
     CDS             complement(7267..7902)
                     /locus_tag="VQU30_001219"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000290646.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-alkyl-2-acetylglycerophosphocholine esterase"
                     /protein_id="HET2447332.1"
                     /translation="MAVQLLENWLLKEQEKIQTKYRHLNHISVVEPNILFIGDSIVEY
                     YPLQELFGTSKTIVNRGIRGYQTGLLLENLDAHLYGGAVDKIFLLIGTNDIGKDVPVN
                     EALNNLEAIIQSVARDYPLTEIKLLSILPVNEGEEYQQAVYIRSNEKIQNWNQAYQEL
                     ASAYMQVEFVPVFDCLTDQAGQLKKEYTTDGLHLSIAGYQALSKSLKDYLY"
     gene            complement(7904..8731)
                     /locus_tag="VQU30_001220"
     CDS             complement(7904..8731)
                     /locus_tag="VQU30_001220"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HET2447333.1"
                     /translation="MMIKVIATDMDGTLLDARGQLDLPRLEKILDQLDQRGIRFVIAT
                     GNEIHRMRQLLSPLVDRVVLVVANGARIFENNELIQAQTWDDAIVNKALAHFKGRACQ
                     DQFVVTGMKGDFVKEGTIFTDLESFMTPEMIEKFYQRMQFVDELTSDLFGGVLKMSMV
                     VGEERLSSVLEEINALFDGRVRAVSSGYGCIDILQAGIHKAWGLEELLKRWDLKSQEI
                     MAFGDSENDVEMLEMAGIAYAMENADEKAKAVATALAPANSQGGVYQVLENWLEKGE"
     gene            complement(8753..9089)
                     /locus_tag="VQU30_001221"
                     /pseudo
     CDS             complement(8753..9089)
                     /locus_tag="VQU30_001221"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398793.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="poly-gamma-glutamate biosynthesis protein"
     gene            complement(9090..9806)
                     /locus_tag="VQU30_001222"
     CDS             complement(9090..9806)
                     /locus_tag="VQU30_001222"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001843873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CapA family protein"
                     /protein_id="HET2447334.1"
                     /translation="MAHGDLLYHDGLFFSAKKEDGTYDFHENFEYVTPWLKQADLAIG
                     DFEGTINKDHYLAGYLLFNAPVEVMDAIKEAGYHVLDLAHNHILDSQIEGVISMADII
                     EKAGITPIGVYTHEPRDQAPLVIKEVNAIKVALLAYSYGFNGIEQYIFQEDYNRYLSD
                     LNEDKIKAEVERAEKEADITIIMPQMGVEYRLEPTEEQKALYHKMIDWGADIIFGGHP
                     HVVEPSKTVEKDGDKKLIIY"
     gene            10329..10940
                     /locus_tag="VQU30_001223"
     CDS             10329..10940
                     /locus_tag="VQU30_001223"
                     /EC_number="3.5.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015058782.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide deformylase"
                     /protein_id="HET2447335.1"
                     /translation="MSAIERITKAAHLIDMNDIIREGNPTLRAIAEEVTFPLSDQEII
                     LGEKMMQFLKHSQDPVMAEKMGLRGGVGLAAPQLDISKRIIAVLVPNIVEEGETPQEA
                     YDLEGIMYNPKIVSHSVQDAALGEGEGCLSVDRNVPGYVVRHARVTVDYFDKDGEKHR
                     IKLKGYNSIVVQHEIDHINGIMFYDRINEKDPFAVKDGLLILE"
     gene            10985..11713
                     /gene="rlmB"
                     /locus_tag="VQU30_001224"
     CDS             10985..11713
                     /gene="rlmB"
                     /locus_tag="VQU30_001224"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006151108.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA
                     (guanosine(2251)-2'-O)-methyltransferase RlmB"
                     /protein_id="HET2447336.1"
                     /translation="MKTNDIVYGVHAVTEALLANTGNKLYLQEDLRGKNVEKVKELAT
                     EKKVSISWTSKKSLSEMTEGAVHQGFVLRVSEFAYSELDYILAKTRQEENPLLLILDG
                     LTDPHNLGSILRTADATNVSGVIIPKHRAVGVTPVVAKTATGAIEHVPIARVTNLSQT
                     LDKLKDEGFWTFGTDMNGTPCHKWNTKGKIALIIGNEGKGISSNIKKQVDEMITIPMN
                     GHVQSLNASVAAAILMYEVFLNRL"
     gene            complement(11752..12663)
                     /gene="trxB"
                     /locus_tag="VQU30_001225"
     CDS             complement(11752..12663)
                     /gene="trxB"
                     /locus_tag="VQU30_001225"
                     /EC_number="1.8.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001847397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin-disulfide reductase"
                     /protein_id="HET2447337.1"
                     /translation="MYDTIIIGAGPAGMTAALYAARSNLKVALIEGGLPGGQMNNTSD
                     IENYPGYANISGPELAEKMFEPLENLGVEHIYGYVENVEDHGDFKKVMTDDQTYETRT
                     VIVATGSKHRPLGVPGEEELNSRGVSYCAVCDGAFFRDQDLLVVGGGDSAVEEALFLT
                     RFAKTVTIVHRRDQLRAQKVLQDRAFANEKISFIWDSVVKEIKGENRVESVVFENVKT
                     GQVTEQAFGGVFIYVGLDPLSDFVKELNIQDQAGWIVTDSHMKTAVDGIFAVGDVRLK
                     DLRQVTTAVGDGAIAGQEAYKFITEHS"
     gene            complement(12729..12953)
                     /locus_tag="VQU30_001226"
     CDS             complement(12729..12953)
                     /locus_tag="VQU30_001226"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000924294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4059 family protein"
                     /protein_id="HET2447338.1"
                     /translation="MLLQLFSLYFESLILTTILVLIFLGIWIGLRAMSGVDKTARARQ
                     AHLYDMIMIGVLVVPVLSFAVMSLILVFKA"
     gene            complement(13031..13774)
                     /locus_tag="VQU30_001227"
     CDS             complement(13031..13774)
                     /locus_tag="VQU30_001227"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397450.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HET2447339.1"
                     /translation="MIKISNLSKSFSGQTVLDHLNLDIQKGEVVALIGSSGAGKSTFL
                     RSLNYLETPDSGSIQIDGFSVDFSKITQEEILALRRKLSMVFQQFNLFERRTALDNVK
                     EGLVVVKKLSDQEATKIAKEELAKVGLSDRENHYPRHLSGGQKQRVALARALAMKPDV
                     LLLDEPTSALDPELVGEVEKSIADAAKSGQTMILVSHDMSFVAQVADKILLLDKGKII
                     ESGTPDEIIHTPKEERTKEFFASYKRTYI"
     gene            complement(13774..14574)
                     /locus_tag="VQU30_001228"
     CDS             complement(13774..14574)
                     /locus_tag="VQU30_001228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001103446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HET2447340.1"
                     /translation="MNVTTILASDWYQNLMQLIPDGKLFSLRSVFDGIPRIVQQLPTT
                     IMLTIGGALFGLVLALLFAIVKINRVKILYPLQAFFVSFLKGTPILVQLMLTYYGIPL
                     ALKALNQQWGTGLNINAIPAAAFAIVAFAFNEAAYASETIRAAILSVNPGEIEAARSL
                     GMTRAQVYRRVIIPNAAVVATPTLINSLIGLTKGTSLAFSAGVVEVFAQAQILGGADY
                     RYFERFISVALVYWVVNIGIESLGRFIERKMAISAPDTVQTDVKGDLR"
     gene            complement(14732..15088)
                     /locus_tag="VQU30_001229"
     CDS             complement(14732..15088)
                     /locus_tag="VQU30_001229"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000889075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arsenate reductase family protein"
                     /protein_id="HET2447341.1"
                     /translation="MLEFIEYPKCSTCKKAKQELNQLGVDYKAVHIVEETPSQEVILN
                     WLETSGFELKQFFNTSGIKYRELGLKDKVGSLSNQEAAELLASDGMLLKRPILVENGT
                     VKQIGYRKSYEELGLK"
     gene            complement(15101..15613)
                     /locus_tag="VQU30_001230"
     CDS             complement(15101..15613)
                     /locus_tag="VQU30_001230"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001170346.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methylated-DNA--[protein]-cysteine
                     S-methyltransferase"
                     /protein_id="HET2447342.1"
                     /translation="MQKKYVKILYSSPIGILSLVADDHYLYGIWVQEQKHFERGLGDE
                     TIEEVVSHPILDPVIACLDDYFKGKPQDLSNLLLAPIGTNFEKRVWDYLQGIPYGQTV
                     TYGQIAQDLQVASAQAIGGAVGRNPWSILVPCHRVLGAGKRLTGYAAGVEKKAWLLEH
                     EGVDFKDINK"
     gene            complement(15613..16107)
                     /locus_tag="VQU30_001231"
     CDS             complement(15613..16107)
                     /locus_tag="VQU30_001231"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000405845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HET2447343.1"
                     /translation="MEIRLAFPNEVDAIMQVMEDAKKCLADAGSDQWQNGYPNADVII
                     DDIISGQAYVALEEGELLAYAAVTKSPEEAYEAIYEGNWQAGESEYLVFHRIAVAADV
                     QGKGVAQTFLEGLIEGFDYLDFRSDTHAENKVMQHIFEKLGFKQVGKVPVDGERLAYQ
                     KLKK"
     gene            16242..16688
                     /locus_tag="VQU30_001232"
     CDS             16242..16688
                     /locus_tag="VQU30_001232"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000858725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1836 domain-containing protein"
                     /protein_id="HET2447344.1"
                     /translation="MKTTFSYPKWAEIPNIDLYLDQVLLYVNQVCAPISPNKDKGLTA
                     SMVNNYVKNGYLTKPDKKKYQRQQIARLIAITTLKSVFSIQEIAQTLNTLQTQASSDQ
                     LYDAFVDYMNQGIDPANPIIQTSCQTVKLYHQTLDLIDHTQEEVIQ"
     gene            16685..17332
                     /locus_tag="VQU30_001233"
     CDS             16685..17332
                     /locus_tag="VQU30_001233"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001097995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hemolysin III family protein"
                     /protein_id="HET2447345.1"
                     /translation="MNTSLKLSKQLSFGEEIANSVTHAVGAVIMLILLPISSIYSYEA
                     HGFLSSIGVSIFVISLFLMFLSSTIYHSMAYGSTHKYVLRIIDHSMIYVAIAGSYTPV
                     VLTLMNNWFGYLIIVIQWGTTIFGILYKIFAKKVNEKFSLALYLIMGWLVLAIIPAII
                     SQTTPVFWSLMVTGGLCYTVGAGFYAKKKPYFHMIWHLFILAASALQYIAIVYYM"
     gene            complement(17353..17934)
                     /gene="pdxT"
                     /locus_tag="VQU30_001234"
     CDS             complement(17353..17934)
                     /gene="pdxT"
                     /locus_tag="VQU30_001234"
                     /EC_number="3.5.1.2"
                     /EC_number="4.3.3.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000689933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal 5'-phosphate synthase glutaminase
                     subunit PdxT"
                     /protein_id="HET2447346.1"
                     /translation="MKIGILALQGAFAEHAKVLDQLGVESVELRNLDDFQQDQSDLSG
                     LILPGGESTTMGKLLRDQNMLLPIREAILSGLPVFGTCAGLILLAKEITSQKESHLGT
                     MDMVVERNAYGRQLGSFYTEAECKGVGKIPMTFIRGPIISSVGEGVEILATVNNQIVA
                     AQEKNMLVSSFHPELTDDVRLHQYFINMCKEKS"
     gene            complement(17935..18810)
                     /gene="pdxS"
                     /locus_tag="VQU30_001235"
     CDS             complement(17935..18810)
                     /gene="pdxS"
                     /locus_tag="VQU30_001235"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012054698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal 5'-phosphate synthase lyase subunit
                     PdxS"
                     /protein_id="HET2447347.1"
                     /translation="MTENRYELNKNLAQMLKGGVIMDVQNPEQARIAEAAGAAAVMAL
                     ERIPADIRAAGGVSRMSDPKMIKEIQEAVSIPVMAKVRIGHFVEAQILEAIEIDYIDE
                     SEVLSPADDRFHVDKKEFQVPFVCGAKDLGEALRRIAEGASMIRTKGEPGTGDIVQAV
                     RHMRMMNQEIRRIQNLREDELYVAAKDLQVPVELVQYVHEHGKLPVVNFAAGGVATPA
                     DAALMMQLGAEGVFVGSGIFKSGDPVKRASAIVKAVTNFRNPQILAQISEDLGEAMVG
                     INENEIQILMAERGK"
     gene            complement(18962..20341)
                     /locus_tag="VQU30_001236"
     CDS             complement(18962..20341)
                     /locus_tag="VQU30_001236"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398482.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HET2447348.1"
                     /translation="MSKIVVVGANHAGTACINTMLDNFGNENEIVVFDQNSNISFLGC
                     GMALWIGEQIDGAEGLFYSDKDKLEAKGAKVYMNSPVLSIDYDNKVVTAEVEGKEHKE
                     SYEKLIFATGSTPILPPIEGVEIVKGNREFKATLENVQFVKLYQNAEEVINKLSDKSQ
                     HLDRIAVVGGGYIGVELAEAFERLGKEVVLVDIVDTVLNGYYDKDFTQMMAKNLEDHN
                     IRLALGQTVKAIEGDGKVERLITDKESFDVDMVILAVGFRPNTALADGKIELFRNGAF
                     LVDKKQETSIPGVYAVGDCATVYDNARKDTSYIALASNAVRTGIVGAYNACGHELEGI
                     GVQGSNGISIYGLHMVSTGLTLEKAKAAGYNATETGFNDLQKPEFMKHDNHEVAIKIV
                     FDKDSREILGAQMVSHDIAISMGIHMFSLAIQEHVTIDKLALTDLFFLPHFNKPYNYI
                     TMAALTAEK"
     gene            20636..21559
                     /locus_tag="VQU30_001237"
     CDS             20636..21559
                     /locus_tag="VQU30_001237"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000175414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD:protein FMN transferase"
                     /protein_id="HET2447349.1"
                     /translation="MTLRSHSERLMGTTITISLVDEQADIFLQKSFDLLKELEYRFNA
                     NSQESELMEINYQAGISPVTVHPDLFELISLGLEHSLALSSHLNISIGPLIQTWRIGF
                     SDAKVAQPQEIESVLPLINPHGIELDSSTSTVFLKQKGMKIDLGCLAKGYSADKVAQF
                     LRKEGVTSALINLGGNILTIGKNQARGDNPWQIGIQDPANPRGNHLMTIPVVNKSVVT
                     SGIYERHLTVDGQDYHHIFDSQTGYPVETELASLTIISDKSVDGEIWTTRLFGERPAS
                     ILWQVESLEGIEVILIDKEGHLSCSSGIPTL"
     gene            21619..22224
                     /locus_tag="VQU30_001238"
     CDS             21619..22224
                     /locus_tag="VQU30_001238"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006153967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent oxidoreductase"
                     /protein_id="HET2447350.1"
                     /translation="MLKLIAIVGTNSKRSTNRQLLQYMQKHFADKAEIELVEIKTIPV
                     FNKPADKQVPAEILEIAAKIEEADGVIIGTPEYDHSIPAVLMSALAWLSYGIYPLLNK
                     PIMITGASYGTLGSSRAQLQLRQILNAPEIKANVLPDEFLLTHSLQAFNPSGDLVDLD
                     VIKKLDAIFDDFRIFVKITEKLRNAQELLRKDAEDFDWENL"
     gene            22242..>23482
                     /locus_tag="VQU30_001239"
     CDS             22242..>23482
                     /locus_tag="VQU30_001239"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000673688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent oxidoreductase"
                     /protein_id="HET2447351.1"
                     /translation="MKFVGLVGSNYDQSYNRKLLEFIRRNFKFKFELEVLEIDEVPMF
                     NQDEKWDESFQLRFLYNKITRADGVIIATPEHNHTISASLKSVLEWLSYEVHPFENKP
                     VMIVGASYYDQGTSRAQVHLRKILDAPGVNAYTLPGNEFLLGKAKEAFDNNGNITNEG
                     TVKFLETCLDNFVKYVGVVSKLKKPKPIESEDLDCGKPIATTITEVDPDDPEWVEKVA
                     AITGAVSGDTYVKLDHGILTVNQIDMFLKAMPFELTYADDNNQFLYYNNAHQDPDTMF
                     AKRVPPQSGSRMSTVHGSLPPARMKNVEWVIGTLRNGNQEYVRTIVPGSPAGVINTHN
                     YQAMYYPDGSYAGINEIVFNFQPWLDWYLKETGQRLVGGSGPFAPAAGGHGDADATSG
                     ASDSGDAGGHGGDADATAGAS"
BASE COUNT         6972 a         5279 c         4282 g         6949 t
ORIGIN      
        1 atacttgagg ctgtattcaa ttgcccttcc tagttttgaa cccgataaaa ctgactgacg
       61 ccggcaccaa gcaaagaaat cttccattag gttggagctc ttcttgacgt ttctgtagtc
      121 gttcatcagc tggcaaagcc tcccagtctc tttccaagaa aaataactga tcacaataag
      181 ctaaaccttt agctcctaag gatgatttat ccgcttgctt gggggtcgct tcaaaaaact
      241 tccttctcac atgcgcccaa catccaacaa gtgcagcttc ttccagttga cgataagctt
      301 ctagcggttc gcagtttacc aagcttagcg tcgccttgct cctaaacctt ggactgctat
      361 cgcataggca gaactagagg actaaagtcc taagttactg ccgcaacata tcacaatgca
      421 catagccaga ataatctcct aggaattctt gtactactga accacttcga cactgatcat
      481 ggtggtaaag cgtaatccct tgtttctctg atttacctga caaaaaagtc caatagtaag
      541 tcagctgact atcactttct aagacccgat aagaggtttc atctgcatga agaagaggtt
      601 gttctaacaa cttttctcgt aaaaggttat aaagggactc taaatagtat tgactcgcct
      661 tgatatgcca attagcaatt tccttacgtg tgattggtaa acccatccta gcccaatctt
      721 cttcttggcg ataattaggt accttcagat taaacttctg atggatggtg tgagcgataa
      781 tagaagctga gtcaatagtc tcgttataaa ggggctttag gaataggagc tttcacaatt
      841 ttatcactcg gatttttatc actgcatgct tggcatttgt aagcgtgttg gatatgatct
      901 atgcgtttta attgcgcagg aataaagact aattcttgtc gttgaagggt tgctccaatc
      961 tcttttagat ctccctgaca atcagagcaa atgctctctt ctacttgatg atgaacttct
     1021 tctgaatcaa attgggcaag aagagcttgg cgtttccctt tagatttctt acgtttgtag
     1081 gtaatttcct ctgtttcaac tgggaacatc tccatctttc tcagatggag actcttcctc
     1141 aaaaaggttg agttgtccag aggggcaaac acttttctca gaggattttc catagagctt
     1201 ttgagtcaga taagccactt gttcacgaag aagggcaagt gcattggtga gactatcaat
     1261 tgtagcactc tgttgttgaa tgattttcaa tcttcttcca tgggcttccc ctccttgttt
     1321 tctaccttta ttatactaaa aagaaagtcc tcatttcaat agaaatcacg actttctgat
     1381 ggatttattt ttggagtgat agaaaagtcc ttcataagcc agtctacttg ttcagatgtg
     1441 agagctttga catccttttc tgtactgggc caagtcagtc tgccgttccc aaagcgttta
     1501 tatagtagcc aaaatccttg accatcccag taaagggctt taaagcggta tttacgtcca
     1561 ccacaaaaga gaaaaacttg acctgagaaa ggatctaatt caaagtgggt tttaaccaga
     1621 taagccagtg aatcaatgcc ttgcctcata tccgttttcc cacatacgag atagacctgc
     1681 cctaggctag atagatgaat tgtcatagag caacacctta tccaaaagct gttctaccat
     1741 ttcgagattg agagattgaa aaaaacttac ttcaagcttg ccaatacgaa ttttaagcag
     1801 aatatcattt ctctttttag aatcaaaagg acgagattgt ggaatctcta caggaacaat
     1861 aggttgtggc attaaaatat cctccaatag ttttacttta ctaatagtat acaggaggaa
     1921 ctccatgaat gatagatacc ttgttatgac gcgattacta tattagaaag ttggctctct
     1981 aattaaatta attctcatta tatatatcaa aagaccgcag cttgaaaact acggtctaat
     2041 tttttgtcca aatgtaaacc acttggaact attattcaat ttattctttt tagtaaatgt
     2101 tcccgtttta atcccagtta cagtttttaa tcctctgtaa ccgttgattt tacaaagctt
     2161 ttaatttttt tgcgattatt cccactcaac tgttgcaggt ggtttacttg taatatcgta
     2221 gacgatacgg ttaacatgat ccacttcatt tacgatacgt actgagattt tttgaagtac
     2281 ttcccatgga attttggcaa aatcagcagt cataccatcg atagaagtga tagcacggat
     2341 tgcaatcgtg tagtcatatg tacgaccgtc acccataaca ccgactgaac gaacgcctgt
     2401 gttaacagtg aagtattgcc aaatatcgcg gtcaagtcca gctttagcga tttcttcacg
     2461 aagaatagcg tctgattcac gaacggtttc aagtttctct tcagtgattt cacccatgac
     2521 acggatagca agtcctggtc ctgggaatgg ttggcgccat acgatatggt ctggcatacc
     2581 aagctctgta ccaagagcac gaacttcatc cttgtaaaga gtattgagtg gttcaatcaa
     2641 ttcaaactgc atatcttctg gaagaccacc cacgttgtgg tgtgacttga tagtttgagc
     2701 tgtatccgta ccagactcga taacatctgt atataaagta ccttgagcaa ggaatttcac
     2761 atctttgagc ttgcttgctt cgtcatcgaa tacatagaca aactcgttac cgatgatttt
     2821 acgtttttgt tcaggatcag aaacgccagc aagtttgtca aggaaacgtt tagcagcgtc
     2881 tgctttgacg atattcaaac caaacttacc accgagcatg tccataactt gatcagcttc
     2941 gcctttacga agaagaccgt ggtctacgaa gatacagatc aattgatcgc caatcgcttt
     3001 ttggagaaga accccaacga cagatgagtc aacaccacct gatagaccaa gaaggacacg
     3061 tttatcaccg acggtttcac gaattttttt gatctgcatg tcaatgaaat tatccattga
     3121 ccagtcacct ttagccttac aaatgttaag ggcaaagtta cgaaggatat catttccgta
     3181 tacagaatga cgaacttctg ggtggaattg gataccgtaa atgtgtttat ctgggttttc
     3241 gatggctgcg tatgggcagt cagctgatgt acctgtacga acaaagtcag caggaatctc
     3301 agtaaccgca tcaccatggc tcatcaaaac agtctgttca tcaggtgttg attcaaaaag
     3361 cgctgatggt gtgtgagtta gggttgattg accgtattca cgatttccag catcacctgc
     3421 aggaacaact tttcctccaa gtttatgggt caataactgc ataccataac agattcccaa
     3481 aattggaatt ccgagttcga agatttctgg gtcaatatca aatgaaccat cttcatatac
     3541 agaatttgga ccacctgata gaataattcc tacaggattg acttcacgaa cttcagcagc
     3601 tgaaatttta tggcttttta gttctgaaaa aacaccaatc tcacggatac ggcgtgaaat
     3661 cagctggttg tactggctac catagtccaa tacgatgatt ttttctacat cttgcaaatc
     3721 agttgaaatg ttgctcatct ttttcctttc tcaaaagaaa tatcttttct caatattcta
     3781 tcacaaataa gggcgaatta ccaactaaac aaggcgaagt ttgacttttt ctagtttatt
     3841 ggggtacaat agagaaaaga tagaaatgaa gtgaaaaata tgctacctgc ttatatgaaa
     3901 atccatgatc agataaaaaa ggatattgac gagcaccgtt gggctattgg tgagaggctt
     3961 cccagtgaaa gagatttagc tgagcagttt gcggtcagtc gcatgaccct ccgccaagcc
     4021 gtatctctat tagtcgaaga aggcgtctta gagcgccgtg taggaagcgg cacctttgtt
     4081 tccagtactc gagtacaaga aaagatgcga gggacaacca gttttactga aattgtcaaa
     4141 tcccaaggta aagttccctc tagccagctc atttcctaca aaaaaaccat tcccaatgag
     4201 caagaagttg ccaagctagg aatttttcca acggacaata ttatccgaat ggagcgggtc
     4261 cgctatgccg accaagttcc cctagtttat gaagttgctt ctattcctga aaaattcatt
     4321 aaggacttta aaaaagaaga aatcacaagt catttcttcc aaaccttgca aaaacatggc
     4381 tatcgtatcg gcaaatctca acagaccatc tatgctcgcc ttgctaaaga aaagattgcc
     4441 cactatttgg aagttgaaaa aggacatgct attcttggat tgacccaggt ttcctaccta
     4501 gaagatggta ctgcttttga atacgtaaaa agtcaatatg taggcgaacg ctttgaattt
     4561 tatcttgaaa ataattagat taccacgcaa aaactctctg tcacggacaa agagtctttt
     4621 ttatttttct aagaataaat ctttcaaaga aatcaaagtt acagcaaaca atatcattgc
     4681 cataccaaga aaatcaatgg gataaaattg ttcattcatt attaagaagg caaagaaaat
     4741 cgccgatatt ggctcaattg aagccaacaa gcttgacttg accggtccta tcagactggc
     4801 tcctttaagg aaagctgtat aggcaaagac agtcccgata aggataatgc ctgcaaacgc
     4861 aaggagaaaa tcaagactag tcgggatatc ggcctgtaga acccctgtaa aaggaagggc
     4921 gaccaaacct gctatgacca ttcccacacc aatgagcaag ctgctccccc actttttaat
     4981 caaggctatg ggtaaaatga tatacagagc ataagtcaag gcagaaaaga gaccccagaa
     5041 cagaccagca ggtgtcatgg ataactggtc caactgccca tgtgttgcga tcaggaaggt
     5101 tcctccgatg gcgaatatga tggaaactat ctctcccagt gtcggtgcca ccctatcctt
     5161 gatacagcta taaattaaaa ttccgacagg acaaacatac tgaagcaccg tcgctgttcc
     5221 cgcattggtc tcctgaatag cagacagata ggcgaattgg ttgagaaaaa gaccaatcag
     5281 agcaaaaata agaagagaca gcaaactctt tctatccttt aaaaagacca gtattttatc
     5341 ctttgcagta gcataagcca agagcatgag aattccacca gcgattaaaa gacgcaagtt
     5401 ggtcaagacc agagccgaaa ttccgtgtgc cattaggtat tggccactcg ttcctgacaa
     5461 cccccaagca ataccagcca caactgttag taaagtccct tttaaactat ttgacatgtc
     5521 tctccttact cttctttgcg aatcaagttc atcacttgat tgcggtctaa tatccattga
     5581 gctctctcgt ccttttcata ggtacgattc gataggaaaa tagtggcttc ttgcttctga
     5641 cgattccaca tgataaaggt acctgtatag cccgtatggt ctagccaatc tccttccaaa
     5701 ttccatgcta aagaacgttc cttgtcatcc aaaggagaaa aattttgatt taagtctctt
     5761 gcaaaatcat ctgctaaata gtgttctaaa aagatttgta aatcctttat agtcgaaaat
     5821 aaaccagcac tcccagcatg tctacccagg agacgagcct tgggatcatg cactatgcct
     5881 gcctctacac ctctaactgt tggaacagca agctcaactg gcccaaactt ggtttccgtc
     5941 attccccaag gtttccagac ttgatccttt aaaatcacat ccaaatcttg attaaaaatt
     6001 ctttccaaaa taaagcccaa cagcaaaaaa tggacatccg aataaagaaa ggctggctga
     6061 cttcgtctgt tgagatgaaa catcgcttcc tttaattcag gggctgttaa aagatcacga
     6121 ttaggaataa aaggatcaag gtctgttgca tgagtcaaga gctggcgaat agtgatgtct
     6181 ggataatcac tctcaggtaa aaaatctatt accagtctat caatatctaa ttgacctatt
     6241 tcccacaaga aggtacaaac tgtgccaacc ccaacaacct tgctgacact agctagatca
     6301 taaactagtc ctgcctcagt ctgcaagcca tgctctgggt cactctggcc taaatagaac
     6361 tctgtccatt gattgtcctt aaaatacgca aaagaggctc cgggataaat tcctgcctcg
     6421 atttgttctt ctattttttt aataatcttg gtccacttca tacttcttca aaccacaatt
     6481 caacattatt tctatcttta ccaaggaaga atttttcaga cttaggaata aaatattcag
     6541 tagactcaaa cttctggcga agacttgcta tgtctaattc attgaccaag aacttgagca
     6601 tagataagtc ccaggtaacc gtattgtcca cagtcaaatc ctgcccctga gctggaataa
     6661 aatcaaggga tgccccaatt tcagatgatt ccaagaaact ttcgatatca gttgggagat
     6721 gtaattccat agaaatctca aatttactta aagaaattga tgccaaatct gtttgaaatt
     6781 caggcttttc tcctacttct actagacttg ctctgtcatc ttccgcatga atcaaaatca
     6841 aatcatcttc tggtgagaaa atttcaaaag cgtagccatt ttgaccttta tataatcgat
     6901 gaatcgaatc tgttttagat aagattcctt caatttctaa gggattttcc accttgacaa
     6961 tcaatctagc tagttttttt cttccctcta ccttacgagt acgcatactg ggagcttctt
     7021 ctaaaaccag cttttcaaga cccgtttggt cacctagtga cagaaaggcc gattcttcta
     7081 acaaggcctt cattccaagg gtttcaatat aaaatgtttc atttaatttt ctattattag
     7141 cttttaaagt aggaataatc cgtacaatct gatttacatt cataaattcc tccgtcactt
     7201 tttattttaa aggattttag aattttttac aagatattat gctcaaattt aacattattt
     7261 agctatttag taaagatagt ctttcaagga ttttgacaaa gcctgataac cagcaatact
     7321 gaggtgcagt ccatcagttg tatattcttt tttgagttgg cctgcttggt ctgtcaaaca
     7381 atcaaatact ggcacaaatt ccacctgcat ataggcagat gcaagctctt gataggcttg
     7441 attccagttc tgaatttttt cattcgagcg gatatagact gcctgctggt actcctctcc
     7501 ctcattgaca ggcaaaatgg aaagcaattt aatctctgtc aatggataat cgcgagcaac
     7561 ggattgaatg atagcttcga gattattgag agcctcattc acaggaacat cctttccgat
     7621 atcatttgtc ccaatcagaa gaaaaatttt atctactgct ccaccatata gatgagcatc
     7681 aagattctct agtaacagtc ctgtctgata gccacgaatt cctcgattga caatcgtctt
     7741 tgaagtccca aatagctcct gtagaggata atactcgaca atggaatccc caataaaaag
     7801 aatgtttggt tctacaacag aaatgtgatt taggtgacga tacttagttt gaattttttc
     7861 ttgttccttt aggagccaat tttctaataa ctgtactgcc acttcattct cctttttcta
     7921 accagttttc caagacttga taaactcctc cttggctgtt ggctggtgct agagcagtcg
     7981 ccacagcttt ggctttctca tcagcatttt ccatcgcata ggcaattcca gccatttcaa
     8041 gcatttcaac atcattttca ctatcaccaa aagccatgat ttcttgggat ttcaagtccc
     8101 agcgcttgag taattcctcc aagccccatg ctttatgaat cccagcttgg aggatatcaa
     8161 tgcaaccata gccactggat acagctcgga cacggccatc aaagagagca ttgatttctt
     8221 ccaaaaccga actcaaacgt tcctcaccaa caaccatgct catcttgagc acaccaccaa
     8281 agaggtcaga tgttaattca tccacaaatt gcatccgttg gtagaatttt tcaatcattt
     8341 ctggagtcat aaaactttca agatctgtaa aaatcgtacc ttccttgaca aaatcaccct
     8401 tcatccccgt tacaacaaac tggtcctgac acgctcgacc cttgaaatga gccaaagcct
     8461 tgttgacaat ggcgtcatcc catgtctgag cctgaatcaa ttcattgttt tcaaaaatac
     8521 gagcgccatt agcaacaacc agaaccactc gatccaccaa gggactcagt agttgtctca
     8581 tgcggtgaat ttcattgccc gtcgcaatga caaaacgaat gcccctttga tccaactgat
     8641 ctaaaatctt ttccaatcgt gggagatcaa gctgacccct agcatccagc aaggtcccat
     8701 ccatatctgt cgcaattacc ttaatcatca tttactttcc tctggattca agctaatacc
     8761 acttcaatcc cacatgttca ttcatttctt tataggctgt atcaattcgt tccttagtcg
     8821 cttcatctaa ctggtcacga tgactgccac ccctctataa aatcttccaa aatataagtt
     8881 tggtaatgat acaagggata tccttctggt gaaaaggttc cctttggtgt tcgattgacc
     8941 caagtaggat gagctttagc tgttccgata gttgtttttc catccttctt cttgatggtg
     9001 acatccatga gaacaccacg ttcagtccac ttagcattct cttcatctcc catagattca
     9061 atccgttgat tggaaatgaa gttccccatt taatagataa tgagtttctt atctccatct
     9121 ttttcaaccg ttttagatgg ttcaacaacg tgaggatgcc ctccaaagat aatatccgct
     9181 ccccaatcga tcatcttgtg ataaagagct ttttgttctt cagttggttc caatcgatac
     9241 tcaacaccca tctgaggcat gataatggtg atatctgctt ccttctctgc ccgttcgact
     9301 tcagccttta tcttatcttc gtttaaatct gaaagataac gattatagtc ttcctgaaaa
     9361 atatactgct caattccatt gaaaccatag gaataggcta acaatgcaac cttgatagca
     9421 ttcacttcct taatgaccag cggagcctga tcacgtggtt cgtgcgtata aactccgatt
     9481 ggagtgattc cagctttctc aataatatcg gccattgaaa taactccctc aatttgcgaa
     9541 tccaaaatat gattatgagc taaatccagc acatgataac ctgcttcctt aatagcatcc
     9601 ataacttcaa caggagcatt aaagagaaga taacccgcta aataatgatc cttattaatg
     9661 gttccttcaa aatcaccaat agctaaatct gcttgcttga gccaaggagt cacatactca
     9721 aaattttcat gaaagtcata ggtaccgtct tcttttttag ctgaaaagaa aagtccatcg
     9781 tggtagagca aatccccgtg ggccataatt ctggcagttt tttcctcttc ctactcctga
     9841 gacttttgct tagtcccctc ttgagaaata gtatctcgtt tttgactagt caagggattc
     9901 cttggaagct ttcaaacaac aagaccaagc ccattgataa accaactgct agcaagagta
     9961 tcgccacaaa tcccttattg ctccacttgc gataactcct aaaaagttta ccaagccctt
    10021 cataaaacga aaagctaaac caccctgatt tcgattttgt cttctttgta tcttcattct
    10081 ccctactttc ttatgcaagc cttttctttt tattatatca cagataagta tttctttcac
    10141 aattgaattg aacttcccat ctattttcta taaatcctaa atgccataat gctttcaatt
    10201 cttgtcattt tgtgatatca tgtagaggta atgaaaggaa atgaactaat ccacagtggc
    10261 ttattccaag tataccactt gggctttggc agtagttaac tgcactaaac ataatataag
    10321 gagagaaaat gtctgcaata gaacgtatta caaaagctgc tcacttaatt gatatgaacg
    10381 atattatccg tgaagggaat cctactctac gcgcgattgc tgaggaagtc actttccccc
    10441 tatctgacca ggaaatcatc ctaggcgaaa agatgatgca attccttaaa cattcccaag
    10501 atcctgtcat ggctgaaaaa atgggactcc gcggtggtgt tggactggct gctccccagt
    10561 tagatatctc aaaacgcatt atcgctgttt tggtacctaa tattgttgaa gaaggcgaaa
    10621 ctccacagga agcctacgat ttggaaggca ttatgtacaa tccaaaaatc gtctctcact
    10681 ctgttcaaga tgctgctctt ggcgaaggag aaggttgcct gtctgttgac cgtaacgtgc
    10741 ctggctatgt tgttcgccat gcccgcgtta ctgttgacta ctttgacaaa gatggagaaa
    10801 aacaccgtat caaactcaaa ggctacaact ccattgttgt tcagcatgaa attgaccaca
    10861 ttaacggtat catgttttac gatcgcatca atgaaaaaga cccatttgca gttaaagatg
    10921 gtttactgat tcttgaataa agaaaatccc gttgcaagac ggggttttgt gttataatag
    10981 aggcatgaaa acaaatgata ttgtctatgg tgtccacgcc gttaccgaag ccctccttgc
    11041 aaatacagga aacaaactct acctccaaga agatctccga ggtaagaatg ttgagaaagt
    11101 caaggaacta gctacagaaa agaaggtgtc catttcttgg acatcaaaaa aatctctctc
    11161 tgagatgact gaaggtgctg ttcatcaagg ttttgttcta cgagtgtctg aatttgccta
    11221 tagcgagcta gattacatcc ttgcaaaaac acgccaagaa gaaaatccac ttctattgat
    11281 tctagatggt ctaaccgatc cccataatct gggttctatc ttgcgaacag ccgatgcgac
    11341 caatgtttca ggtgtcatca ttcccaagca ccgtgctgtc ggagtaactc ctgtcgttgc
    11401 caaaacagcc acaggtgcta ttgaacacgt tccaattgcc cgagtgacaa acctcagtca
    11461 aaccttagat aaactcaagg atgaaggctt ctggaccttt ggaacggata tgaacggtac
    11521 tccttgccac aagtggaata caaaagggaa aatcgccctc atcatcggaa atgaaggaaa
    11581 aggcatctct agcaacatca aaaaacaggt cgatgaaatg attaccattc cgatgaatgg
    11641 acatgttcaa agcctcaatg ccagtgttgc tgcagccatt ctcatgtacg aagtttttct
    11701 aaatagacta taaaaaagtt tccagtcatc tgattggaaa cttttttatg attaactatg
    11761 ttctgtgata aacttgtagg cttcttgacc agcgatagct ccatctccaa ctgctgttgt
    11821 tacttggcga aggtctttca agcgaacatc tccaactgca aagataccgt cgactgcagt
    11881 cttcatgtgg ctatctgtca caatccagcc tgcctgatct tggatattca attctttaac
    11941 aaaatcgcta agagggtcca aaccaacata gataaagaca ccaccgaagg cttgctctgt
    12001 cacttgacct gttttcacat tttcaaaaac gacagattct actctgtttt cacccttgat
    12061 ttccttcact acagaatccc agataaagct gattttttca ttcgcaaagg cgcgatcttg
    12121 taaaaccttt tgggcacgaa gttggtcacg acggtgaaca atggtaacag tcttagcaaa
    12181 acgagtcaag aagagggctt cttcaacagc tgaatctcca ccaccaacta ccaataaatc
    12241 ttggtcacgg aagaaagcac catcacacac agcacagtaa gaaacaccac gactgttcag
    12301 ttcttcttct ccaggcactc ccaaaggacg gtgtttagaa ccagttgcta cgataactgt
    12361 acgtgtttca tatgtttggt catcagtcat cactttctta aaatcaccat ggtcttcgac
    12421 attttcaaca taaccataaa tgtgctcaac accaagattt tcaagtggtt caaacatctt
    12481 ttcagccaat tcaggtccac taatattagc gtatcctggg taattttcga tatcagatgt
    12541 attattcatc tgaccacctg gcagaccacc ttcaatcaaa gctactttta gattgcttcg
    12601 agcagcatac aaggccgcag tcatccctgc aggtccagca ccgataataa tagtatcgta
    12661 catatagatt ccttctttct tgttgtaact atctttattc taactctttc ttgtcaatca
    12721 cgcaaggatt atgccttgaa aacaagaatt aaactcataa ccgcaaagga taatactggg
    12781 acaaccaaga ctccaatcat aatcatatca tagagatggg cttggcgagc cctggctgtc
    12841 ttatcaactc ccgacatggc tctcagacca atccaaatcc ctaaaaaaat cagaacaagg
    12901 atggtggtca agatcaaact ctcgaaatat aaagaaaata gttgcagtag catgatttct
    12961 ctcatttcta tcttttttaa agagtaaact cagctagtcc aactaactga gttttccttt
    13021 atctattata tcaaatataa gtccgtttgt aactagcgaa gaattctttt gtccgctctt
    13081 ctttaggggt gtggataatc tcatccggag ttccagactc gatgattttc cccttatcta
    13141 ataagagaat tttatccgca acttgggcta caaaggacat gtcatgactg accaaaatca
    13201 tggtctgacc tgacttagca gcatctgcaa tagacttttc tacttcaccg accaattctg
    13261 ggtcaagggc tgaagttggt tcgtctaaga gcaaaacatc tggtttcata gcaagcgcac
    13321 gcgctagggc aacccgttgc ttctgtccac ctgataaatg gcgaggataa tggttttcac
    13381 ggtccgaaag cccaacctta gccaactctt ccttggcaat cttagtcgct tcttggtcag
    13441 ataatttctt gacaacaacc aagccttctt tcacattatc aagtgctgtt cgacgttcaa
    13501 ataaattaaa ctgttggaaa accatagaca acttacggcg tagggcaagg atttcttctt
    13561 gagtgatttt agaaaaatca actgaaaaac catcaatctg aatagagcca ctgtcaggtg
    13621 tttcaagata attgagactg cgaagaaagg ttgattttcc agctcctgaa gaaccaatca
    13681 aggctacaac ttcccctttt tgaatatcca agttcagatg atccaagaca gtctgtcctg
    13741 aaaaggattt gcttaaattc gaaatcttaa tcattaacga aggtctcctt tcacatctgt
    13801 ttgcactgta tcaggtgcag aaatagccat ttttctctcg atgaaacgac cgaggctttc
    13861 aattccgata ttgactaccc aataaacaag ggcaacagag atgaagcgtt caaaatagcg
    13921 ataatcagct ccacctagaa tctgagcttg ggcaaagact tccacaacac ccgcactaaa
    13981 agctagagat gttcccttgg tcaaaccgat gagggaatta atcaaggttg gagtagctac
    14041 caccgctgca ttaggaataa tcactcgtcg ataaacttgc gctcgggtca tacccagact
    14101 gcgcgccgcc tcaatctcac caggattaac tgagagaatg gctgcacgaa tggtttcact
    14161 agcataagct gcctcattaa aggcaaaagc gacaatcgca aaagctgcag ctggaatcgc
    14221 attgatattg agaccagttc cccattgctg attgagggct ttcaaagcca aagggattcc
    14281 gtagtaggtc aacatgagtt gcaccaaaat cggtgtccct tttaagaaac taacaaagaa
    14341 ggcctgcaag ggatataaaa tcttgacacg attgatcttc acaatggcaa aaagaagcgc
    14401 caaaaccaag ccaaaaaggg caccaccaat tgtcaacata attgttgttg gaagttgttg
    14461 gacaattcta gggattccat caaagaccga acgtaggcta aacagcttgc catccggaat
    14521 caattgcatc aagttttggt accaatctga tgctaaaatc gttgtaacat tcataaaaac
    14581 atcctcttct gataatgatt cattctacca tgcttctgcc gtcaatgaaa ttatttgcta
    14641 cggtcagata cagactttgt ctacctacta gtttatcata ctttgaaaca gggaagttat
    14701 atattttatc tatcaaagag atagataaaa actatttcag tcccagttct tcataagatt
    14761 ttcgataacc gatttgctta acagttccat tttctactaa aatgggccgt tttaacaaca
    14821 taccgtcact tgctagcaac tcagccgctt cttggtttga caaacttcct accttatctt
    14881 ttagccctaa ttcacggtat ttgataccac tggtgttgaa aaattgcttc aattcaaatc
    14941 ctgaggtttc tagccaattc aaaatgactt cttggctagg tgtttcttcc acgatatgga
    15001 cggctttata gtccacacct aattgattta attcttgttt tgctttttta caagttgaac
    15061 atttggggta ttcgataaat tctaacatgt gcttctcctt ctatttgttt atatctttaa
    15121 aatctacgcc ttcatgctcc aagagccaag ctttcttttc cactcctgca gcatagcctg
    15181 tcagacgctt gcctgctccc aacacacgat gacaaggtac taggatagac caaggattgc
    15241 gtcccactgc tccaccaatt gcttgagcag aagccacttg caggtcttga gcaatttgtc
    15301 cataggtcac tgtctgacca taaggaatgc cctgtaaata gtcccaaact ctcttttcaa
    15361 aattcgttcc gattggcgcc aagagcaagt tggataaatc ctgaggcttg cctttaaagt
    15421 aatcatctaa gcaagcaata actgggtcta aaataggatg actaacaact tcttctatcg
    15481 tttcatctcc tagtcccctc tcaaaatgct tctgctcctg aacccaaatt ccatacaaat
    15541 aatggtcatc agctacaagt gatagaatac caattggtga ggagtagagt atttttacat
    15601 acttcttttg cattatttct ttaatttttg ataggccaag cgttcgccat ctactggcac
    15661 cttaccaact tgtttaaaac caagtttttc aaaaatatgt tgcataacct tgttttcagc
    15721 atgcgtatct gagcgaaaat caagataatc aaaaccttca atcaagccct ctaagaaggt
    15781 ttgagcaact ccttttccct gcacatctgc tgccacagca atacggtgaa agactagata
    15841 ctctgactct ccagcttgcc agtttccctc ataaatagct tcataggcct cctctggact
    15901 cttggtcaca gcagcatagg ctagcagttc tccctcttcc aaggctacgt aggcttgccc
    15961 tgagatgata tcatcgataa taacatctgc atttggatag ccattttgcc actggtcact
    16021 accagcatct gctaaacatt ttttggcatc ctccatcacc tgcatgatgg catctacttc
    16081 atttggaaaa gctaaacgaa tttccatctt ttttcctcat ttctgactag tttctcccat
    16141 catagcataa tttaagtatt tctacaagca gttaaaactt gactttgtgt ttttgttatt
    16201 ttataatcta gttatcaaaa ctatataaaa aggagttgaa aatgaaaact accttttcct
    16261 acccaaaatg ggcagaaatt ccaaacattg acctctatct ggaccaggtt ttgctctatg
    16321 tcaatcaggt ctgcgcccct atctctccta ataaagacaa gggcctaaca gcatctatgg
    16381 tcaacaatta tgtgaaaaat ggttacctga caaagcctga caaaaaaaaa taccaacgcc
    16441 aacagattgc ccgtttgatt gctatcacaa ccctcaagtc tgtattttct attcaagaaa
    16501 tagcccagac acttaatact ctacaaactc aagcaagttc agaccaactc tacgatgctt
    16561 ttgtggacta catgaaccaa ggaattgacc cagctaaccc tattatccaa accagctgcc
    16621 aaaccgtcaa actctatcat caaactctag acttaatcga tcatactcaa gaggaggtaa
    16681 tccaatgaac actagtctta aactcagcaa acaactcagt tttggagagg agattgctaa
    16741 tagcgtgacc catgctgtgg gtgcagtcat catgcttatc ttgctgccta tttcatccat
    16801 ctatagttat gaagcacacg gatttttatc ctctatcggc gtttccattt tcgtcatcag
    16861 tctctttctc atgttcctat catccaccat ttatcactct atggcctatg gttcgaccca
    16921 caaatatgtt ttgcgaatca ttgaccattc tatgatttac gttgccattg ccggctcata
    16981 cacgcccgtt gtcttgacct tgatgaataa ctggtttggc tatctgatta ttgtcatcca
    17041 atggggaacg accatctttg gtattctcta taaaatcttt gctaaaaagg tcaatgagaa
    17101 atttagcctt gctctttacc tgattatggg ctggttggtt ctggctatca ttcctgccat
    17161 tatcagtcaa acgacacccg ttttctggag tctcatggta actggcggac tctgttatac
    17221 agttggagct ggattttatg ccaagaaaaa accttatttc cacatgattt ggcatctctt
    17281 tatcctagct gcgtccgcac ttcaatacat cgctattgtt tattacatgt aaaaaagttg
    17341 agaaattcaa tctcaacttt tttctttaca catattgata aagtactggt gcaagcgcac
    17401 atcatcagtc aattctggat gaaaagaact taccaacata tttttttctt gggctgcaac
    17461 aatttgattg ttcactgttg ctagaatttc tacaccctca ccaacactac tgataatcgg
    17521 accacggata aaggtcattg gaatcttgcc aactccctta cattctgctt ccgtgtagaa
    17581 acttcctaat tggcgcccat aagcattacg ctcgaccacc atatccatag ttcctagatg
    17641 actctctttc tgagaagtga tttccttagc cagcaaaatt aagcccgcac aggtcccaaa
    17701 cactggtaag ccagatagaa tggcttctcg gatgggaagt agcatgttct ggtcacgtaa
    17761 gagcttgccc atggttgtag actcaccacc aggcaaaatc aaacccgaca agtcactctg
    17821 atcttgctga aaatcatcta gatttctgag ttctacactc tcgacaccta attgatctag
    17881 cacttttgca tgttctgcaa aggccccttg caaggccaat attccaattt tcatctattt
    17941 tcctcgttca gccatgagaa tttggatttc attttcatta ataccaacca tggcttctcc
    18001 taaatcttca gagatttgag ctaggatttg aggattacgg aagttagtca cagccttaac
    18061 aatggcactc gctcgtttaa caggatctcc tgacttgaaa atacctgaac cgacaaagac
    18121 cccctctgcc cctaattgca tcattaacgc agcatctgct ggcgttgcaa cacctccagc
    18181 agcgaaattt acaactggca attttccatg ttcatgaaca tattggacca attctacagg
    18241 gacttgcaaa tccttggcag caacataaag ctcgtcctca cgtaagtttt gaatgcggcg
    18301 aatttcctga ttcatcatac gcatatgacg aacagcttgg acgatatccc ctgtccctgg
    18361 ttctcctttg gtacgaatca tggaagcacc ttcagcgata cgacgcaagg cttcacccaa
    18421 atccttagca ccacagacaa aaggaacttg gaattctttc ttgtccacat ggaaacggtc
    18481 atcagctgga gatagaactt cactctcgtc gatataatca atttcaatag cctctaaaat
    18541 ctgagcttca acaaaatgcc cgattctgac cttagccatt actggaatac taaccgcttc
    18601 ttggatttcc ttaatcatct ttgggtcgct catgcgggaa actcctccag ctgcacgaat
    18661 atcagccgga attcgttcca aggccatcac agctgccgca ccagcagctt ctgcgatacg
    18721 agcctgttca ggattctgca catccataat aacaccaccc ttgagcatct gtgccaagtt
    18781 tttatttagt tcataacgat tttcagtcat ttgttttatc ctcatcattt gtattggtag
    18841 ctaccttttc attttaagtc agaacagaat gaagcacaag ataaaaaaac tataattgta
    18901 tggggacaga ttggctaaaa actatctgac cttaacttaa ggccagatag ctcattcatt
    18961 tttatttttc agccgtaagg gcagccattg tgatgtagtt gtatggttta ttgaagtgtg
    19021 gcaagaagaa gaggtctgtc aatgccaatt tatcaattgt cacatgctct tggatagcaa
    19081 gtgagaacat gtggattccc atgctaattg caatatcatg tgaaaccatt tgggcaccaa
    19141 gaatttcacg gctatctttg tcaaagacaa tcttaattgc tacttcatgg ttgtcatgtt
    19201 tcatgaattc tggtttttga agatcgttaa agcctgtttc agttgcgttg taaccagcag
    19261 ctttcgcttt ttcaagagtc aaaccagttg aaaccatgtg aagaccgtag attgagatac
    19321 catttgaacc ttgaacaccg attccttcca attcatgtcc acaagcgttg taggcaccaa
    19381 cgataccagt gcgaacagca tttgaagcaa gagcgatata gcttgtatct ttacgagcat
    19441 tgtcataaac agtcgcacag tcaccaacag cgtaaacgcc tgggatagat gtttcttgtt
    19501 tcttgtctac aaggaaggca ccgttgcgga agagttcgat cttaccatca gcaagggctg
    19561 tgtttggacg gaaaccaact gcaaggataa ccatatccac gtcaaagctt tctttgtcag
    19621 taatcaagcg ttcaacttta ccatcacctt cgattgcttt aacagtttga cctagagcca
    19681 agcggatgtt gtgatcttcc aagttcttcg ccatcatttg tgtgaagtct ttgtcatagt
    19741 aaccgttcaa gacagtatca acgatatcaa caaggacaac ttcttttcca agacgttcaa
    19801 aggcttcagc aagttcaaca ccgatgtaac caccaccaac aacggcgata cggtcgagat
    19861 gttggctctt gtcagaaagt ttattgataa cttcttcagc attttggtac aatttcacga
    19921 attgtacgtt ttcaagagtt gctttaaatt cgcggtttcc tttaacaatt tcaacacctt
    19981 cgattggtgg caagattggt gtagaacctg tagcgaaaat caatttctcg tatgattctt
    20041 tgtgttcttt tccttcaact tctgctgtaa ccactttgtt atcatagtcg attgaaagaa
    20101 ctggtgaatt catataaacc ttagcacctt tagcttctaa tttgtcttta tcagaataga
    20161 acaagccttc agcaccgtca atttgttcac caatccaaag agccattcca catcctagga
    20221 aagagatgtt agagttttgg tcaaatacaa caatttcgtt ctcatttcca aaattatcca
    20281 acatggtatt gatacatgct gtaccagcgt ggttagcacc gactacaacg attttactca
    20341 taaaaaattt cctgccttca ttctaaattt actttactag tataccattt accgttagcg
    20401 tttacaaggg ggggactatt atttcagcat tttttatcaa aaataattcc ccatttatcc
    20461 tgttttcaag cctcatgaat tttatgagca tatttcttga ctttttccaa attttgtttg
    20521 tgaaaattct aactttatgg tattataata acatgaaaat aaaatgtaag ggcttcaatt
    20581 tagatgatta tttgatattg caacttattt tctataagag aaaggagttg gtagcttgac
    20641 tcttcgttca cattctgaac ggctaatggg gactactatc actatttcat tagtggatga
    20701 gcaagccgat atctttctcc aaaaatcctt tgacttgctc aaagagcttg aataccgctt
    20761 caacgccaat agtcaagaat ctgagttgat ggaaatcaat tatcaagcag gaatatcccc
    20821 cgtcacagtt catccagacc tgtttgagct gatttcactt gggttagagc atagcctagc
    20881 gctctctagc cacctcaata tcagcattgg tcccttaatt caaacctggc gtatcggttt
    20941 ttcagatgcc aaggtcgccc agcctcaaga aattgaatcg gtgctgcctc taatcaatcc
    21001 tcatggtatc gagttagatt cttctacttc tactgtgttt ttaaaacaga aaggaatgaa
    21061 gatcgatcta ggttgtttag ccaaaggata cagtgcggat aaggttgccc aatttcttag
    21121 gaaagagggg gtgacttctg ccttgatcaa tctgggaggg aatatcctga ccattggaaa
    21181 aaatcaggca agaggggata acccatggca aatcgggatt caagacccag ccaatcctag
    21241 gggaaatcat ttaatgacca tccctgttgt caataaatct gtcgtgactt caggcattta
    21301 tgaacgtcac ctgaccgtcg atggacaaga ttaccatcac atttttgaca gtcaaacagg
    21361 atatcctgtt gaaacggaac tagcgagtct aacaatcatc tctgataaat cagtcgatgg
    21421 cgaaatctgg acgactcgac tctttggaga aagacctgct tctatcctct ggcaagtcga
    21481 aagtttggag ggcatcgaag tcatcctcat cgataaagaa ggccacctaa gctgttcttc
    21541 aggaattcct actctataga gacaactgtt tcaatggaat tttaaaattg tattatgtaa
    21601 aaagagaaag gaaatatcat gttaaaactt attgctattg ttggaacaaa ttcaaaacgt
    21661 tctacaaacc gtcaattgct tcaatacatg caaaaacact ttgctgacaa agctgaaatt
    21721 gaacttgttg aaatcaagac cattcctgtc ttcaacaaac cagctgacaa gcaagtacct
    21781 gctgaaatat tggaaattgc tgctaaaatc gaagaggcag atggcgttat tatcggtact
    21841 cctgagtatg atcactctat tccagctgtt ttgatgagcg ctcttgcttg gttgtcttat
    21901 ggtatttacc cacttttgaa caaaccaatc atgattacag gtgcttctta cggtacgctt
    21961 ggttcatctc gtgcccaatt gcaacttcgt caaatcttga atgctcctga aatcaaggca
    22021 aatgttcttc cagatgaatt cttgctcaca cactctcttc aagcatttaa cccaagtggc
    22081 gacttggttg accttgatgt tatcaagaaa ttggatgcca tctttgatga cttccgtatc
    22141 ttcgtgaaga ttactgagaa attgcgcaat gcgcaagaat tgcttcgcaa agatgctgaa
    22201 gactttgact gggaaaattt gtaagatagg agaccgaaag aatgaaattt gttggacttg
    22261 ttggatcaaa ctacgatcaa tcatataacc gcaaactctt ggaatttatc cgtcgcaatt
    22321 tcaaattcaa atttgaatta gaagtacttg aaatcgacga agttccaatg tttaaccaag
    22381 acgaaaaatg ggacgaaagc ttccaattgc gtttcttgta taacaagatt acacgtgctg
    22441 atggtgtcat tatcgccact cctgagcaca accacactat ctcagcttca ctcaaatctg
    22501 tacttgaatg gctttcatac gaagttcatc catttgaaaa caagcctgtt atgattgtgg
    22561 gtgcatcata ctatgaccaa ggaacatcac gtgctcaagt tcaccttcgt aaaatccttg
    22621 atgctccagg tgttaatgcc tacacgcttc caggtaacga attccttctt ggtaaagcta
    22681 aggaagcttt tgataacaac ggaaatatca ccaacgaagg cactgttaaa ttccttgaaa
    22741 cttgcttaga taactttgtt aaatacgtag gagtcgtttc gaaattgaaa aaaccaaaac
    22801 caatcgaatc agaagacttg gattgtggaa aaccaatcgc tacaaccatc acagaagttg
    22861 accctgacga tccagaatgg gtagaaaaag ttgcagcaat cactggtgct gtttctggtg
    22921 atacctatgt caaattggac cacggtatcc taacagttaa ccaaattgat atgttcttga
    22981 aagctatgcc atttgaattg acatacgctg acgacaacaa ccaattcctc tactacaaca
    23041 acgctcacca agatccagac actatgttcg ctaaacgtgt accacctcaa tcaggtagcc
    23101 gtatgtcgac tgttcatggt tctcttccac cagcacgtat gaagaacgta gagtgggtta
    23161 tcggaacact tcgcaacgga aaccaagaat acgtccgtac gatcgttcca ggttctcctg
    23221 caggtgttat caacactcac aactaccaag caatgtacta tcctgatgga tcatacgctg
    23281 gtatcaatga aatcgtcttt aacttccaac catggcttga ctggtaccta aaagagactg
    23341 gtcaacgttt ggtgggtggt agcggaccat ttgctcctgc tgccggaggt catggagacg
    23401 ccgatgctac ttctggcgct tctgattcag gggatgctgg aggccacggt ggtgacgcag
    23461 acgctacagc cggtgcaagt ta
//
LOCUS       DAVBBO010000031        23312 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ST1
            SAMEA2066453-rid20184263.denovo.031, whole genome shotgun sequence.
ACCESSION   DAVBBO010000031 DAVBBO010000000
VERSION     DAVBBO010000031.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2066453
            Sequence Read Archive: ERR351777
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 23312)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 23312)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980402.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980402.1
            Genome Coverage       :: 176x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:17:33
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,141
            CDSs (total)                      :: 2,104
            Genes (coding)                    :: 1,953
            CDSs (with protein)               :: 1,953
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 16S)
            partial rRNAs                     :: 1 (23S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 151
            CDSs (without protein)            :: 151
            Pseudo Genes (ambiguous residues) :: 0 of 151
            Pseudo Genes (frameshifted)       :: 73 of 151
            Pseudo Genes (incomplete)         :: 76 of 151
            Pseudo Genes (internal stop)      :: 40 of 151
            Pseudo Genes (multiple problems)  :: 32 of 151
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..23312
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2066453-rid20184263.denovo.031"
                     /strain="ST1"
                     /db_xref="taxon:1313"
     gene            complement(196..654)
                     /locus_tag="VQU30_001240"
     CDS             complement(196..654)
                     /locus_tag="VQU30_001240"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399107.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3021 domain-containing protein"
                     /protein_id="HET2447352.1"
                     /translation="MKKQVFHDAAAGVLIGLILSILFSLIYAPNTYAPLNPYSLIGQV
                     MDQHQVHGALVLLYCTLIWAAIGMLFNFGNRLFSRDWSMLRATLTHFFLMLAGFVPLA
                     TLAGWFPFHWIFYLQLIIEFAIVYLIIWAILYKREAKKVDHINQLLEHRK"
     gene            complement(651..1091)
                     /locus_tag="VQU30_001241"
     CDS             complement(651..1091)
                     /locus_tag="VQU30_001241"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000861967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HET2447353.1"
                     /translation="MKVELQISETYEEEKLIVQAPQPTDKVQKVIEFAENLDQREKIK
                     GKIDDQVYLVEIGKIQRFYIENRKVLAETASQTYSIDLRLYQVLKLLPTNFIQISQSE
                     IINIDSISHLKLTPNGLVEIFLKNESFTYSSRRYLKTIKEKLEL"
     gene            1675..2541
                     /locus_tag="VQU30_001242"
     CDS             1675..2541
                     /locus_tag="VQU30_001242"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000537001.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HET2447354.1"
                     /translation="MGTLLATRLKNRRKELKMSQRELAEGICKQGQISRLESGEFTPG
                     ADFLHALAKKLKVSMDYFFDEQVVEKVEELSEFKKLAQTFITNRNYESLKYIYELENV
                     KAHRLSLADKIYMEWIKSLIDFYFYGQKEDAIVRLEGVLSQLSVSDLNYLQVSNTLFN
                     FYYDIGDLGRFNKIREKLEYQVNHLNLSTIEELELSIKFNYNVCRYLWLQKNIEEAIT
                     KITATIKQCKAYRTNYLLADLYLLMGNVSENFSSKSSVKEYFETAYFLYKLEENMSMT
                     LKVEHYIADITE"
     gene            2878..3435
                     /locus_tag="VQU30_001243"
     CDS             2878..3435
                     /locus_tag="VQU30_001243"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000358739.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopantothenate--cysteine ligase family
                     flavoprotein"
                     /protein_id="HET2447355.1"
                     /translation="MDKKNLLVLVTGSVGASNVDTYLYYIKKFYNVKVILSENSKKFI
                     SKELISYFCDKVYDEIFVEEVVPHVFLPYESDLLLILPATANVIGKIANGIADDLVTA
                     TVLNFNKKIIFCPNMNSTMWDNHIVQRNVSILKELGHIFLFESKKTYEVGLRKAIDST
                     CSMLQPQSLVKELIKLENIVLEEGH"
     gene            3656..4762
                     /locus_tag="VQU30_001244"
     CDS             3656..4762
                     /locus_tag="VQU30_001244"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000608718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal-dependent decarboxylase"
                     /protein_id="HET2447356.1"
                     /translation="MINKKIQQVVLESLQNFLNGNFISPCVVYDFGLLETVLDEFKNQ
                     IPVTFNYQLFYAVKANSNEKILEFLVDKIDGVDVASLSELDVAKKFFPPTQISVNGPA
                     FSYETLYNLIKKQYKVDINFLEHLQQFSPKESVGIRVTEPDELNNRMSRFGINICSDN
                     WTSNLQNPLITRLHFHFGEKDDKFIVKLDKILFKLQEINKLREVREINLGGGFMKLFM
                     ENRLKEFFLSLMEIYKKYDIDSTVTTIIEPGSAITSFSAYMITSPVNVSEVNEQQVIT
                     LDTSIYTNTLWFVPHIITTLNSSSKERYSTILYGNTCYEHDKYKMKVSLPRLTQNSSI
                     VFFPVGAYIKSNHSNLHRNDFMREVYLWTKNLTY"
     gene            4738..6129
                     /locus_tag="VQU30_001245"
     CDS             4738..6129
                     /locus_tag="VQU30_001245"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000358548.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2447357.1"
                     /translation="MDKKLDILDKVKEYLGNKTTQILDNQYKEFLKLNDIRRAFGISE
                     KVLNNSFNFTSKEFNDLINNENYLFEYACRIREEWRKKCFNHSYRFLCSPIITDDFLN
                     TKTLRSSQIEYKYERYLSKSSIGDRAVDGFVSFNTLTANGMSAIKLCLEILNSIFFKK
                     KIDLLYSTGYYETRFLLNNLAKSGISCYEVSNCELDKDKFYNVFMMEPNRADLTLQKT
                     DFKIVEYFVKYKNNSIKVVILDISYQGSNFKLVEFLEKFKFANVIIFVVRSLIKLDQM
                     GLELTNGGIIEVFIPNHLRKLKNFIEEEFNKFRNSHGANLSLYEYCLLDNSLTLKNDW
                     NYSDLVMKFTSNFYADIKDLFMENSDIEIIHEEGVPFVFLDLIGEGKKEYEMFFQWLN
                     FFYKQLGITLYARNSFGFRNLTVEYFGIIGTERYIFKICPGVYKGLSYYLMKFLLKSF
                     SNEYLKTTDEVNR"
     gene            6126..7304
                     /locus_tag="VQU30_001246"
     CDS             6126..7304
                     /locus_tag="VQU30_001246"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000792992.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HET2447358.1"
                     /translation="MKNLIKLLIIRLIVNLADSVFYIVALWHVSNNYSSSMFLGIFIA
                     VNYLPDLLLIFFGPVIDRVNPQKILIISILVQLAVAVIFLLLLNQISFWVIMSLVFIS
                     VMASSISYVIEDVLIPQVVEYDKIVFANSLFSISYKVLDSIFNSFASFLQVAVGFILL
                     VKIDIGIFLLALFILLLLKFRTSNANIENFSFKYYKREVLQGTKFILNNKLLFKTSIS
                     LTLINFFYSFQTVVVPIFSIRYFDGPIFYGIFLTIAGLGGILGNMLAPIVIKYLKSNQ
                     IVGVFLFLNGSSWLVAIVIKDYTLSLILFFVCFMSKGVFNIIFNSLYQQIPPHQLLGR
                     VNTTIDSIISFGMPIGSLVAGTLIDLNIELVLIAISIPYFLFSYIFYTDNGLKEFSIY
                     "
     gene            7729..7962
                     /locus_tag="VQU30_001247"
     CDS             7729..7962
                     /locus_tag="VQU30_001247"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000623387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HET2447359.1"
                     /translation="MISIDLGGTNIKITVLSNDGEIETLWSITTDTSEKGSQIISDII
                     SSIKNKLTERNIPDSDLLGIGMGSCSSYFPCKS"
     gene            8245..10194
                     /gene="mutL"
                     /locus_tag="VQU30_001248"
     CDS             8245..10194
                     /gene="mutL"
                     /locus_tag="VQU30_001248"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004250478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA mismatch repair endonuclease MutL"
                     /protein_id="HET2447360.1"
                     /translation="MSHIIELPEMLANQIAAGEVIERPASVVKELVENAIDAGSSQII
                     IEIEEAGLKKIQITDNGYGIAHDEVELALRRHATSKIKNQADLFRIRTLGFRGEALPS
                     IASVSVLTLLTAVDGASHGTKLVARGGEVEEVIPATSPVGTKVCVEDLFFNTPARLKY
                     MKSQQAELSHIIDIVNRLGLAHPEISFSLISDGKEMTRTAGTGQLRQAIAGIYGLVSA
                     KKMIEIENSDLDFEISGFVSLPELTRANRNYISLFINGRYIKNFLLNRAILDGFGSKL
                     MVGRFPLAVIHIHIDPYLADVNVHPTKQEVRISKEKELMTLVSEAIANSLKEQTLIPD
                     ALENLAKSTVRNREKVEQTILPLKENTLYYEKTEPSRPSQTEVADYQVELTDEGQDLT
                     LFAKETLDRLTKPAKLHFAERKPANYDQLDHPELDLASIDKAYDKLEREEASSFPELE
                     FFGQMHGTYLFAQGRDGLYIIDQHAAQERVKYEEYRESIGNVDQSQQQLLVPYIFEFP
                     ADDALRLKERMPLLEEVGVFLAEYGENQFILREHPIWMAEEEIESGIYEMCDMLLLTK
                     EVSIKKYRAELAIMMSCKRSIKANHRIDDHSARQLLYQLSQCDNPYNCPHGRPVLVHF
                     TKSDMEKMFRRIQENHTSLRELGKY"
     gene            complement(10519..10986)
                     /locus_tag="VQU30_001249"
     CDS             complement(10519..10986)
                     /locus_tag="VQU30_001249"
                     /EC_number="2.5.1.78"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001099498.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6,7-dimethyl-8-ribityllumazine synthase"
                     /protein_id="HET2447361.1"
                     /translation="MNTYEGNLVANNIKIGIVVARFNEFITSKLLSGALDNLKRENVN
                     EKDIEVAWVPGAFEIPLIASKMAKSKKYDAIICLGAVIRGNTSHYDYVCSEVSKGIAQ
                     ISLNSEIPVMFGVLTTDTIEQAIERAGTKAGNKGSECAQGAIEMVNLIRTLDA"
     gene            complement(10987..12192)
                     /locus_tag="VQU30_001250"
     CDS             complement(10987..12192)
                     /locus_tag="VQU30_001250"
                     /EC_number="3.5.4.25"
                     /EC_number="4.1.99.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001842537.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional
                     3,4-dihydroxy-2-butanone-4-phosphate synthase/GTP
                     cyclohydrolase II"
                     /protein_id="HET2447362.1"
                     /translation="MEYRKIQEALEALQKGRLVLVIDDKDRENEGDLICSAQAATTEN
                     VNFMATYAKGLICMPMSESLANQLMLSPMVENNTDNHKTAFTVSIDYKETTTGISAEE
                     RGLTARMCVAEDITPSDFRRPGHMFPLIAKKGGVLERNGHTEATVDLLKLAGLKECGL
                     CCEIMNHDGKMMRTDDLIQFSKKHNIPLITIKELQEYRKVYDQLVERVSTVNMPTRYG
                     NFKAISYIDKLNGEHHLALIMGNIEDEANVLCRVHSECLTGDVLGSLRCDCGQQFDKA
                     MKMIVENGSGVLLYLRQEGRGIGLINKLKAYHLQDQGMDTLDANLALGFEGDLREYHI
                     GAQMLKDLGLQSLHLLTNNPDKVEQLEKYGITISSRISIEIEANPYDSFYLETKKNRM
                     GHILNMEEK"
     gene            complement(12212..12847)
                     /gene="ribE"
                     /locus_tag="VQU30_001251"
     CDS             complement(12212..12847)
                     /gene="ribE"
                     /locus_tag="VQU30_001251"
                     /EC_number="2.5.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000493842.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="riboflavin synthase"
                     /protein_id="HET2447363.1"
                     /translation="MFTGIIEEIGKVERIQKDSRNCKLSIKASKILTDIHLGDSIAVN
                     GICLTVTHFNHQSFTVDVMNETWSRTALTLLKHGSEVNLERALSVNGRLGGHVVTGHI
                     DGTGKISSIKKDDNAVWYQINTQKEILDLIVEKGSITIDGISLTVAKVSKVNFSVSVI
                     PHTLEQTILKSKQVGSTVNLENDILGKYVQKLMDNSPKSEISKELLYQNGF"
     gene            complement(12832..13932)
                     /gene="ribD"
                     /locus_tag="VQU30_001252"
     CDS             complement(12832..13932)
                     /gene="ribD"
                     /locus_tag="VQU30_001252"
                     /EC_number="1.1.1.193"
                     /EC_number="3.5.4.26"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001284110.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional
                     diaminohydroxyphosphoribosylaminopyrimidine
                     deaminase/5-amino-6-(5-phosphoribosylamino)uracil
                     reductase RibD"
                     /protein_id="HET2447364.1"
                     /translation="MSDSKYMKLAIKLAQKGAGYVNPNPMVGAVIVKDNHIIGQGYHE
                     FFGGPHAERNALKNCRESPVGATLYVTLEPCCHFGKTPPCIDAIIDSGITRVVIGSLD
                     CNPIVSGKGVKILEENNLQVTVGILENECLNLIKSFRKYITQHVPYVFMKYAMSMDGK
                     IATKTNQSKWITEEEARKHVHQLRHHVSAIMVGVNTVIQDDPLLTCRLEEGKNPIRII
                     CDTHLRTPLTSKIVKTANDIKTYIATSSEDKNKMKLYQNHGCEILSIKKKGNHIDLSS
                     LMQHLGNMQIDSLVLEGGSLMNWSALEQQIVDELKIYIAPKIFGGSAKFPVGGEGISL
                     PNDAIRLKPYAFSQIGNDYLIESEVIYPCSQE"
     regulatory      complement(14067..14181)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00050"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="FMN riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="flavin mononucleotide"
                     /db_xref="RFAM:RF00050"
     gene            14338..14931
                     /gene="ruvA"
                     /locus_tag="VQU30_001253"
     CDS             14338..14931
                     /gene="ruvA"
                     /locus_tag="VQU30_001253"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000271492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction branch migration protein RuvA"
                     /protein_id="HET2447365.1"
                     /translation="MYAYLKGIITKITAKYIVLETNGIGYILHVANPYAYSGQVNQEA
                     QIYVHQVVREDAHLLYGFRSEDEKKLFLSLISVSGIGPVSALAIIAADDNAGLVQAIE
                     TKNITYLTKFPKIGKKTAQQMVLDLEGKVVVAGDGLPAKVAVQASAENQELEEAMEAM
                     LALGYKATELKKIKKFFEGTTDTAENYIKSALKMLVK"
     gene            14941..15504
                     /locus_tag="VQU30_001254"
     CDS             14941..15504
                     /locus_tag="VQU30_001254"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000166575.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-3-methyladenine glycosylase I"
                     /protein_id="HET2447366.1"
                     /translation="MTKRCSWVKMTNPLYIAYHDEEWGQPLHDDQALFELLCMETYQA
                     GLSWETVLNKRQAFREAFHSYQIHSVAEMTDTELEAMLENPAIIRNRAKIFATRANAQ
                     AFLQLQAEYGSFDAYLWSFVEGKTVVNDVPDYRQAPAKTPLSEKLAKDLKKRDFKFTG
                     PVAVLSFLQAAGLVDDHENDCEWKGLK"
     gene            15501..16178
                     /locus_tag="VQU30_001255"
     CDS             15501..16178
                     /locus_tag="VQU30_001255"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000987430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HET2447367.1"
                     /translation="MMSNKNKGILIFAILYTVLFVFDGVKLLASLMPSAIANYLVYVV
                     LALYGSFLFKDRLIQQWKEIRKTKRKFFFGVLTGWLFLILMTVVFEFVSEMLKQFVGL
                     VGQGLNQSNIQSTFQEQPLLIAVFACVIGPLVEELFFRQVLLHYLQERLPGLLSIILV
                     GLVFALTHMHSLALSEWIGAVGYLGGGLAFSIIYVKEKENIYYPLLVHMLSNSLSLII
                     LAISIVK"
     gene            complement(16319..17350)
                     /locus_tag="VQU30_001256"
     CDS             complement(16319..17350)
                     /locus_tag="VQU30_001256"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000255096.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LD-carboxypeptidase"
                     /protein_id="HET2447368.1"
                     /translation="MVSTIGIVSLSSGIIGEDFVKHEVDLGIQRLKDLGLNPIFLPHS
                     LKGLDFIKDHPEARAEDLIHAFSDDSIDMILCAIGGDDTYRLLPYLFENDQLQKVIKQ
                     KIFLGFSDTTMNHLMLHKLGIKTFYGQSFLADICELDKEMLAYSLHYFKELIETGRIS
                     EIRPSDVWYEERTDFSPTALGTPRVSHTNTGFDLLQGRALFEGKILGGCLESLYDIFD
                     NSRYADSTELCQKYKLFPDLSDWEGKILLLETSEEKPKPEDFKKMLLTLKDTGIFAVI
                     NGLLVGKPMDETFHDDYKEALLDIIDSNIPIVYNLNAGHATPRAIVPFGVHAHVDAQE
                     QVIRFDYNK"
     gene            complement(17605..18288)
                     /locus_tag="VQU30_001257"
     CDS             complement(17605..18288)
                     /locus_tag="VQU30_001257"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000078028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1129 domain-containing protein"
                     /protein_id="HET2447369.1"
                     /translation="MSQIDLQKLTKKNQEFVHIATQQFIKDGKTDAEIQTIFEEVIPQ
                     ILEEQSKGTTARSLYGAPTHWAHSFTVKEQYEKEHPKENDDPKLMIMDSALFITSLFA
                     LVSALTTFFAADQAFGYGLITLLLVGLVGGFAFYLMYYFVYQYYGPDMDRSQRPPFWK
                     SVLVILASVFLWLLVFFATSFLPASLNPVLDPLPLAIIGAALLALRFYLKKRLNIRSA
                     SAGPTRYQE"
     gene            complement(18300..19244)
                     /locus_tag="VQU30_001258"
     CDS             complement(18300..19244)
                     /locus_tag="VQU30_001258"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004250490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium transporter CorA family protein"
                     /protein_id="HET2447370.1"
                     /translation="MKQVFLSTTTEFKEIDTLEPGTWINLVNPTQNESLEIANTFDID
                     IADLRAPLDAEEMSRITIEDEYTLIIVDVPVTEERNNRTYYVTIPLGIIITEETIITT
                     CLEPLPVLDVFINRRLRNFYTFMRSRFIFQILYRNAELYLTALRSIDRKSEQIESQLH
                     QSTRNEELIELMELEKTIVYFKASLKTNERVIKKLTSSTSNIKKYLEDEDLLEDTLIE
                     TQQAIEMADIYGNVLHSMTETFASIISNNQNNIMKTLALVTIVMSIPTMVFSAYGMNF
                     KDNEIPLNGEPNAFWLIVFIAFAMSVSLTLYLIHKKWF"
     gene            19376..22207
                     /gene="uvrA"
                     /locus_tag="VQU30_001259"
     CDS             19376..22207
                     /gene="uvrA"
                     /locus_tag="VQU30_001259"
                     /EC_number="3.1.25.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit UvrA"
                     /protein_id="HET2447371.1"
                     /translation="MQDKIVIHGARAHNLKNIDVEIPRDKLVVVTGLSGSGKSSLAFD
                     TLYAEGQRRYVESLSAYARQFLGNMEKPDVDAIDGLSPAISIDQKTTSKNPRSTVGTT
                     TEINDYLRLLYARVGTPYCINGHGAIKASSVEQIVDKVLELPERQRLQILSPVIRKKK
                     GQHKSVIEKVQKDGYVRVRVDGEVYDVTEVPELSKSKQHNIDVVVDRIVIKEGIRSRL
                     FDSIEAALRIAEGYVIIDTMDNSELLFSEHYACPVCGFTVPELEPRLFSFNAPFGSCS
                     ECDGLGIKLEVDTDLVVPNASKTLHEGALAPWNPISSNYYPNMLEQAMTAFGVAMDKP
                     FEDLSEEDKNLILYGSDGKKFHFHYENEFGGVRDIDIPFEGVINNIKRRYHETNSDYT
                     RTQMRLYMNELTCGTCHGYRLNDQALSVRVGGEQGPHIGEISDLSIADHLDLVSQLTL
                     SENEAIIARPILKEIKDRLTFLNNVGLNYLTLSRSAGTLSGGESQRIRLATQIGSNLS
                     GVLYILDEPSIGLHQRDNDRLIASLKKMRDLGNTLIVVEHDEDTMREADYLIDVGPGA
                     GVFGGEIVAAGTPKQVARNSKSITGQYLSGKRVIPVPEERRVGNGRFIEVIGARENNL
                     QNVTARFPLGKFIAVTGVSGSGKSTLINSILKKAIAQKLNRNSDKPGKFKTITGIEHV
                     DRLIDIDQSPIGRTPRSNPATYTGVFDDIRDLFAQTNEAKIRGYKKGRFSFNVKGGRC
                     EACSGDGIIKIEMHFLPDVYVACEVCHGTRYNSETLEVHYKEKNISQVLDMTVNDAVE
                     FFQHIPKIQRKLQTIKDVGLGYVTLGQPATTLSGGEAQRMKLASELHKRSTGKSFYIL
                     DEPTTGLHTEDIARLLKVLARFVDDGNTVLVIEHNLDVIKTADHIIDLGPEGGVGGGT
                     IIVTGTPEEVAANEASYTGHYLKGKLHHE"
     gene            22200..23261
                     /locus_tag="VQU30_001260"
     CDS             22200..23261
                     /locus_tag="VQU30_001260"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466358.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase P family protein"
                     /protein_id="HET2447372.1"
                     /translation="MNKRVQAFLAKMQEKELDGVIINNLKNVYYLTGFWGSNGTVFIS
                     RDRQVLVTDSRYIIAAKQETSGFEIVADRDELAVIAGIVKDMGLTRIGFEDEISVSYY
                     HRMQAAFAGLNLLPQTQFVEGLRMIKDEAEIAAIRKACSISDQAFRDALDFIKPGKTE
                     IEIANFLDFRMRELGASGLSFDTILASGINSSKPHAHPMHKPVELGEAITMDFGCLYD
                     HYVSDMTRTIYLGHVSDEQAEIYNTVLKANQALIDQAKAGLGFRDFDKIPRDIIIEAG
                     YGDYFTHGIGHGIGLDIHEEPYFSQTSTETIKTGMALTDEPGIYIEGKYGVRIEDDIL
                     ITETGCELLTLAPKELIVI"
BASE COUNT         7035 a         4105 c         4754 g         7418 t
ORIGIN      
        1 agatctgaaa taactgttat gatatagagg attgaaacta gaatagtaca cctctgcttc
       61 taaaacattg ttagaaatcg atttgactgt cctgatcgat ttatcctgtt cttatttcat
      121 ttcactatag taaggtgcag caggataaag aaaaaccgag aagtttcttt ctcggatttg
      181 cttattatga ggttcctatt ttctatgctc caagagttga ttgatgtgat ctactttttt
      241 agcctctctt ttatagagaa tagcccagat gatgagatag acaatcgcaa actcgataat
      301 gagctggagg tagaaaatcc agtggaaagg gaaccaacca gcaagagttg ctagtgggac
      361 aaagccagcc agcataagga agaaatgagt cagagtggca cgaagcatgc tccagtcacg
      421 gctgaataag cgattgccaa agttgaagag cataccaatg gctgcccaga taagtgtgca
      481 gtagagcaag accaaggcac cgtgaacctg atgctgatcc atcacttggc cgatgagaga
      541 gtagggattt agtggtgcgt aggtatttgg tgcataaatg agtgaaaaga ggatagagag
      601 gatgaggccg ataagaacac cggcagctgc atcgtgaaat acttgttttt tcatagttct
      661 aatttctcct tgatggtttt tagataacgg cgtgaagagt aggtgaagct ttcgtttttc
      721 aagaaaattt ctaccagacc gtttggcgtg agcttgaggt gagagatgga atcgatattg
      781 atgatttctg attgggaaat ttggataaaa ttggttggca agagtttaag aacctgatag
      841 agtcgcaaat caatgctgta ggtctgactc gcggtttctg ctagaacctt ccgattctcg
      901 atatagaagc gctgaatctt gccaatctca actagataga cctgatcatc gattttccct
      961 ttgatttttt ctctttggtc cagattttct gcgaactcga tgactttctg aactttatct
     1021 gtcggctgag gtgcttggac aatcagcttt tcctcctcgt aagtctcact aatctgtaat
     1081 tctactttca taaatttctc tccttgtttt tcatacaaaa ttaatctcac ttcttgtaca
     1141 cctttattaa tactcttcaa aaatctcttc aaaccacgtc agcgtcgtct tgccgtagga
     1201 tagttgttga ctttgtcagt tttatctaca acctcaaaac agtgttttga gctgtctgcg
     1261 cctagctttc tagtttgctc tttgattttt attgagtata ccactatttt actccctctg
     1321 gcaaggtact ttgtctatgt ggagggattg ggctcctatg tggtggagct tttctgttct
     1381 ttctgaaata tggtataata gcactaatca atttctagga aaatagatac agaaaggggc
     1441 tgaaagaact aggggaacag ttgtaattag aaggtgatag gtatgaaaag tggcgttgaa
     1501 gctggataag tttataaaga gtttgaatga agaaatgaaa agtaaataag ttgatgatga
     1561 attgcaaaaa tagattttat atacaatttg tatctttcaa atcattgatt tgaattttag
     1621 atttaatcat gttacaatta aaaatgaaat caaatagaag aggaagatgc aaacgtgggc
     1681 acactattag caacaagatt aaaaaataga cgaaaagaat taaaaatgtc tcagcgagaa
     1741 ctagctgaag gtatctgtaa acaggggcaa atcagtcgat tagagagcgg agagtttact
     1801 cctggagcag atttcttgca tgcccttgct aagaagttaa aagtcagtat ggattatttt
     1861 tttgatgagc aggttgtaga gaaagttgag gagttatcag aatttaagaa attagcacag
     1921 acatttatta caaatcgcaa ttatgagtct ttgaaatata tatatgaatt ggagaatgta
     1981 aaagctcacc gcctatcttt agcagataaa atctacatgg aatggataaa atctctgata
     2041 gatttttatt tttacggaca gaaagaagat gcgattgtac gattagaggg ggtattatca
     2101 cagttaagtg tatctgattt gaactatctc caagtttcaa acaccctatt caatttttat
     2161 tatgatattg gagatttagg tcgtttcaat aaaattcgtg aaaaactaga gtatcaagta
     2221 aatcacctca atttgagtac aatcgaagag ttagaactat ctattaagtt taactacaac
     2281 gtttgtcgtt atctatggtt acagaaaaat attgaagaag ctattactaa aattacagct
     2341 actataaaac aatgtaaggc ttacagaacg aattatcttt tggctgattt gtacttattg
     2401 atgggaaatg taagtgaaaa tttttcttct aaaagttcgg tgaaagaata ttttgagacg
     2461 gcatattttc tatacaaact tgaggagaac atgtcaatga ctctgaaagt tgagcattac
     2521 attgcagata taacagaata atgaatacgg tgttcaagtg agcatcgttt ttcaaaccta
     2581 gttcagatac aaaaaagtat caaataaaaa aaaataaaaa aacattataa aaacaattga
     2641 caagctaatt ttgaagtgat aaaataaatg caagaaaaca aaaggagagg tatatgagaa
     2701 gtttgtttaa gaaaatagtt gctgtattag ttattggctt aattctgtta ggaattgcga
     2761 gaacacctca agttcataag atggctagag ggattgatcc tggtcctgcg aattttattt
     2821 agaaatcaat ttctactaat tgagtactaa ttgagtatta atgggtaaaa agattgtatg
     2881 gataagaaaa atttacttgt attggttact ggttcggtag gtgccagtaa tgtagataca
     2941 tacttatatt atataaaaaa attctataat gttaaagtga tactttctga aaattctaaa
     3001 aaatttataa gtaaggaatt aattagttat ttttgtgata aagtttatga tgaaatattt
     3061 gttgaagagg tagttccgca cgtttttctg ccatatgaat ctgacttact tcttatttta
     3121 ccagctacgg caaatgtgat tggcaaaatt gctaatggta ttgctgatga tttagttaca
     3181 gcaactgttt taaactttaa taaaaaaata attttttgtc ccaatatgaa ctctactatg
     3241 tgggacaatc acatagttca aagaaatgta tcaattctaa aggagttggg acatatattt
     3301 ttatttgagt ctaaaaaaac atatgaggta ggattgcgta aagcaataga ttcaacatgt
     3361 tcaatgttac aaccacagtc gttagtaaaa gaacttatca aattagaaaa tattgtcctt
     3421 gaagagggac attaaaaact actgagaata ttaaggaggg gaaaaaatgg aaaattcatc
     3481 aatcgatgta gatatgctgt tggaagaatt gacacaagaa gcaatggtcg ttgttgctgt
     3541 tgataaggac tgttaattta aacttatggc aatatatgaa aggttactgg atgttttaaa
     3601 ttatgcaggc agtagccttt tattatatac aaatggataa agtaaggata atacaatgat
     3661 taataaaaaa atacaacaag ttgttttgga atcattacag aattttttga atgggaactt
     3721 catttcgcct tgtgtagtct atgattttgg cttgctggaa actgtacttg atgaatttaa
     3781 aaatcaaatt cctgtaacat tcaattacca acttttttat gccgttaaag caaattcaaa
     3841 tgagaagata cttgaattct tagtagataa aattgatgga gttgatgtgg cgtcattatc
     3901 tgaattagat gtggctaaaa aatttttccc accaactcaa atttctgtta atggtcccgc
     3961 attttcttat gaaactttat ataatctgat taaaaaacaa tataaagttg atattaactt
     4021 tttggaacat cttcaacaat tttccccaaa agaatctgtt ggaataagag taacggagcc
     4081 agatgaactt aataatcgta tgagtcgatt tggaataaat atttgcagtg ataattggac
     4141 tagtaattta caaaatcctt taattacacg actgcatttt cattttggag aaaaagatga
     4201 taaatttatt gttaagttag ataaaatatt atttaagtta caagaaatta ataaacttag
     4261 agaggttaga gaaataaatc ttggaggcgg ttttatgaaa ttatttatgg aaaatcgttt
     4321 gaaagaattt tttctatcac ttatggaaat ctataaaaag tacgatattg atagtactgt
     4381 gactacaata atagaaccag gtagtgcaat tacttcattt tctgcctata tgattactag
     4441 cccagttaat gttagtgagg tgaatgagca gcaggttatc acgttagaca catcaatata
     4501 caccaataca ttatggtttg ttccgcatat tattacaacg ttaaattcaa gtagtaaaga
     4561 gcgttatagt actattctct atggtaatac ctgttatgaa catgacaagt ataaaatgaa
     4621 agtttcgctt ccaaggttaa ctcaaaatag cagtatagtg ttttttcctg taggagctta
     4681 tataaaaagc aatcattcaa atttacatcg taatgatttt atgcgggagg tatatttgtg
     4741 gacaaaaaac ttgacatatt agataaagtt aaggaatatt taggaaataa aactactcaa
     4801 attctggata atcaatataa agaatttttg aaacttaatg atataaggcg agcgtttggt
     4861 atttcagaaa aagtattaaa caattctttt aattttacga gtaaagaatt taatgattta
     4921 attaataacg aaaattattt attcgaatat gcatgtagaa ttagagagga atggagaaaa
     4981 aaatgcttta atcattctta tcgttttcta tgctcaccta taattacaga tgattttctt
     5041 aacacgaaga cattgagaag tagccaaatt gaatataaat atgagcgata tttatcgaaa
     5101 agttcgatag gcgatagagc ggttgatggc tttgtttcct tcaatacttt aacagctaat
     5161 ggtatgtctg ctattaaact atgtcttgag atattaaact ctattttctt caagaagaag
     5221 attgatttat tatattcaac cggatattat gaaacaagat ttttattaaa taatcttgct
     5281 aaatcaggta ttagttgcta tgaggtaagt aattgtgaat tggataaaga taaattttat
     5341 aatgtattca tgatggaacc caatcgagcc gatttaacat tacaaaaaac tgatttcaag
     5401 atagtagaat attttgttaa gtataaaaat aattcaataa aagtcgttat tttagatatt
     5461 tcatatcaag gttctaattt taaattagta gaatttttag agaaatttaa atttgcgaat
     5521 gtaattattt ttgtggtacg atctttgata aaattagatc aaatgggatt agaattgaca
     5581 aatgggggaa taatagaagt gtttattcct aatcatttga gaaagttgaa aaattttatt
     5641 gaagaggaat tcaataaatt tagaaattct cacggagcta atctaagcct ctatgaatac
     5701 tgtttgcttg ataattcttt aaccttaaaa aatgattgga actattctga tttagttatg
     5761 aaatttacga gtaattttta tgctgatata aaagacttgt tcatggaaaa ttctgatatt
     5821 gaaatcatcc atgaagaggg agtacctttt gtatttttag atttaatagg tgaaggtaaa
     5881 aaagaatatg aaatgttttt tcaatggtta aacttctttt acaaacagct tggaatcaca
     5941 ttgtatgcta gaaatagttt tgggtttcgg aatctaacag tagagtattt tggaattatt
     6001 gggacagaaa gatatatatt taagatttgt ccaggtgttt ataaagggtt aagttattat
     6061 ttgatgaaat ttttattaaa atctttttca aatgaatatt taaaaactac tgatgaggtt
     6121 aatagatgaa aaatttgata aagttgctaa taattagatt gattgttaac ttagcagaca
     6181 gtgtatttta tatagtagca ttgtggcacg ttagcaataa ttattcttcg agcatgttct
     6241 taggaatatt tattgcagta aattatctac cggatttgtt actaatcttt tttggaccag
     6301 ttattgacag agtaaatccg caaaaaattc ttataatatc aattttggtt caattagcag
     6361 tggctgtaat atttttatta ttattaaacc aaatatcatt ttgggtgata atgagtctag
     6421 tgtttatttc agtaatggct agctccataa gttacgtgat agaagatgtg ttgattcctc
     6481 aagtggtaga atatgataag attgtatttg caaattctct ttttagtatt tcgtataaag
     6541 tattagattc tatttttaat tcattcgcat catttttaca ggtggcagta ggatttattt
     6601 tattggttaa gatagatata ggcatatttt tacttgctct atttatattg ttgttgttaa
     6661 aatttagaac tagcaatgcg aatatagaaa acttctcttt caaatattac aagagagaag
     6721 tgttgcaagg tacaaagttt attttaaata ataaattatt atttaaaacc agtatttctt
     6781 taacgcttat aaactttttt tattcatttc agacagtagt tgtaccgatt ttttctattc
     6841 gatattttga tggtccgatt ttttatggta tttttttaac tattgctggt ttgggtggta
     6901 tattgggaaa tatgctagcg ccaatcgtaa taaaatattt aaaatcgaat caaattgttg
     6961 gtgtatttct ttttttgaac ggctcaagtt ggttagtagc aattgttata aaagactata
     7021 ctttatcact tattttattt ttcgtttgtt ttatgtctaa aggagtcttc aatattattt
     7081 ttaattcgtt gtaccaacaa atacctccac atcaacttct tggtagggta aatactacca
     7141 ttgattctat tatttctttt ggaatgccaa ttggtagttt agttgcagga acgcttattg
     7201 atttgaatat tgaattagtg ttaattgcta ttagcatacc ttattttttg ttttcttata
     7261 ttttttatac ggataatgga ttgaaagaat ttagtatata ttagaaatgt ttatgttcat
     7321 tcaaaagcat aatgactata actgaaaaag aaaagtgata tctttaaggt tgttcttctt
     7381 ggtggtgaga ttcgtgagac aacccaagct tttgtcggaa agattaccaa tgctttgatg
     7441 gataggatgt actttagcaa gatgttttta gtggtaacgg tatcgtggat ggacgtgtaa
     7501 taacctcttc tttcgaggag tattttacta aaaaactagc cttggagcgt tccccagaaa
     7561 cggacttact cattgactct tcaaagattt ggggagaaga ttttgcttca tctgttcctt
     7621 gaaaaaagtc acagcagtca tcacagacga tagtactgaa caaaactatg aagagttaga
     7681 aatttatacg caggtgattg tataaaggat ctggaaatag ataagaagtt gattagtatt
     7741 gacctaggtg gtacaaatat taagattact gttctttcaa atgacggtga gattgaaact
     7801 ttgtggagta ttacaacaga tacaagtgag aaaggttctc aaattatatc ggacatcatc
     7861 agttctatta aaaataaatt gaccgaacgg aatattcctg atagcgacct tcttggaatc
     7921 ggtatgggaa gttgctcatc atactttcct tgtaaatcat aggggctata aactctccgt
     7981 ctacttgtcc tgcaacaatt gaagtctgct caaaacgccg tccgctaatc ttttcataga
     8041 ctttctccct tttaggagcc tagctttcta gtttgttctt tgatttttat tgagtatacc
     8101 actattttac tccctctggc aagggacttt gtctatgtgg agggattggg ctcctatgtg
     8161 gtggagcttt tctgttcttt ctgaaatatg gtataatagc actaatcaat ttctaggaaa
     8221 atagatacgg aaaggggctg aaagatgtct catattattg aattgccaga gatgctggca
     8281 aaccaaatcg cagctggaga ggtcattgaa cgtcctgcca gcgtggtcaa agaattggta
     8341 gaaaatgcca ttgacgcggg ctctagtcag attatcattg agattgagga agctggtctc
     8401 aagaaaatcc aaatcacaga taacggttat ggaattgccc acgatgaggt ggagttggcc
     8461 ctgcgtcgcc atgcgaccag taagataaaa aatcaagcag atctctttcg gattcggacg
     8521 cttggttttc gtggtgaagc cttgccttct attgcgtctg ttagtgtctt gactctgtta
     8581 acggcggtgg atggtgctag tcatggaacc aagttagtcg cgcgtggggg tgaagttgag
     8641 gaagtcatcc cagcgactag tcctgtggga accaaggttt gtgtggagga tctctttttc
     8701 aacacgcctg cccgtctcaa gtatatgaag agccagcaag cggagttgtc tcatatcatt
     8761 gatattgtca accgtctggg cttggcccat cctgagattt cttttagctt gattagtgat
     8821 ggcaaggaaa tgacgcggac agcagggact ggtcaattgc gccaagcaat cgcagggatt
     8881 tacggtttgg tcagtgccaa gaagatgatt gaaattgaga actctgacct agatttcgaa
     8941 atttcaggtt ttgtgtcctt gcctgagttg actcgggcta accgcaatta tatcagcctc
     9001 ttcatcaatg gtcgttatat caagaacttc ctgctcaatc gtgctatttt ggatggtttc
     9061 ggaagcaagc ttatggttgg acgttttcca ctggctgtca ttcacatcca tatcgaccct
     9121 tatctagcgg atgtcaatgt gcatccaact aagcaagagg tgcggatttc caaggaaaaa
     9181 gaactgatga ccctggtttc agaagctatt gcaaatagtc tcaaggaaca aaccttgatt
     9241 ccagatgcct tggaaaatct tgccaaatcg actgtgcgca atcgtgagaa ggtggagcaa
     9301 actattctcc cactcaaaga aaatacgctc tactatgaga aaactgagcc gtcaagacct
     9361 agtcaaactg aagtagctga ttatcaggta gaattgactg atgaagggca ggatttgacc
     9421 ctgtttgcca aggaaacctt ggaccgattg accaagccag caaaactgca ttttgcagag
     9481 agaaagcctg ctaactacga ccagctagac catccagagt tagatcttgc tagcatcgat
     9541 aaggcttatg acaaactgga gcgagaagaa gcatccagct tcccagagtt ggagtttttc
     9601 ggacaaatgc acgggactta tctctttgcc caagggcgag atggacttta catcatagat
     9661 cagcacgctg ctcaggaacg ggtcaagtac gaggagtacc gtgaaagcat tggcaatgtt
     9721 gaccagagcc agcagcaact cctagtgccc tatatctttg aatttcctgc ggatgatgcc
     9781 ctgcgtctca aggaaagaat gcctctctta gaggaagtgg gcgtctttct agcagagtac
     9841 ggagaaaatc aatttattct acgtgaacat cctatttgga tggcagaaga agagattgaa
     9901 tcaggcatct atgagatgtg cgacatgctc cttttgacca aggaagtttc tatcaagaaa
     9961 taccgagcag agctggctat catgatgtct tgcaagcgat ctatcaaggc caatcatcgt
    10021 attgatgatc attcagctag acaactcctc tatcagcttt ctcaatgtga caatccctat
    10081 aactgtcctc acggacgtcc tgttttggtg cattttacca agtcggatat ggaaaagatg
    10141 ttccgacgta ttcaggaaaa tcacaccagt ctccgtgagt tggggaaata ttaaaagtat
    10201 aaaaaagtct gggaaaaatt ttcaaaatca gaaaaacgca taaaatcagg tgttcaaaaa
    10261 ccttgatttt atgcgtttta tcatggaaat agttacttca tgttttccta attcttttcg
    10321 aaactctttt taaaccacgt cagttttatc agtaatctca aaacagtgtt ttgagctaat
    10381 tttgccagtt ttatctgtaa catcgaagtt gtgtttgacc actctgcgac tggtttccta
    10441 gtttgctcta tgattttcac agagtattaa attgcgattt tgccaagttt ctttattcgt
    10501 ctaaaagtag agtctgttct atgcgtctaa tgtacgaatt aggttgacca tttcaatagc
    10561 tccttgtgca cactcagaac ccttatttcc tgctttggta ccagctcgtt ctatggcttg
    10621 ttcaattgta tctgtcgtta gcacaccaaa cataacagga atttcgctat ttaaactgat
    10681 ttgggcgatt cccttagata cctcgctaca tacataatca taatgacttg tattccctct
    10741 aatgacagct cccaagcaga taattgcatc atatttttta ctttttgcca tttttgatgc
    10801 aatcagtggt atttcaaaag ctcctggaac ccaggctacc tctatatctt tctcgtttac
    10861 attctctctt ttgagattat ctagtgctcc agataataat tttgaagtta taaattcatt
    10921 aaatctcgct acaacaatac ctattttaat attgtttgct actaaattac cttcataagt
    10981 gttcatttat ttttcctcca tatttaaaat gtgacccatt cgatttttct ttgtttctaa
    11041 ataaaaacta tcgtaaggat tggcttctat ttcgattgat attctactgg aaatggtaat
    11101 tccatatttt tctaactgtt caaccttgtc aggattattt gtcagtaaat gaagtgactg
    11161 aagtcccaga tctttaagca tttgtgctcc aatatgatat tctcttaaat caccttcaaa
    11221 gcctaatgca agattggcat caagcgtatc catgccttga tcttgtaaat gataggcttt
    11281 taatttattg ataagtccaa ttcctcgtcc ctcctgtcgc aagtaaagta agacacccga
    11341 accattctca acaatcattt tcatagcttt atcgaattgc tgtccacaat cgcaacgtaa
    11401 agagcctaaa acatctcctg ttaaacattc ggagtggacc cgacataata cattggcttc
    11461 atcctctata tttcccataa taagagcaag atgatgttcc ccatttagtt tatctatata
    11521 gctaattgct ttgaaattac cgtatctagt aggcatattg acagttgaaa ctcgttctac
    11581 cagctgatca tatacttttc tatattcttg taattctttg atggtaatta gtggaatgtt
    11641 gtgtttcttc gagaactgaa ttaaatcatc tgttctcatc attttgccat catgattcat
    11701 tatttcacaa cataggccac actcttttag tccagctaat tttaataaat caacagttgc
    11761 ttctgtgtgt ccatttcttt ctagaacacc accttttttt gcaattaaag gaaacatgtg
    11821 tcctggcctg cgaaaatcag agggtgttat atcttcagct acacacatac gtgcggtcag
    11881 tcctctctcc tcggcagaaa tacctgtggt cgtttcttta taatcaattg aaactgtaaa
    11941 agcagtctta tgattatctg tattgttttc aaccataggt gaaagcatta attgattagc
    12001 taaactttcg ctcataggca tacaaattaa tcctttggca taagtagcca taaaattaac
    12061 attttctgtt gtagctgctt gtgcagaaca aattaagtct ccttcatttt ctctatcctt
    12121 gtcgtctata acaagaacaa gtcgtccctt ctgcaatgct tctaatgctt cttgtatttt
    12181 tcgatattcc attgactgat tatcctttct gctaaaatcc attttgatat aatagttcct
    12241 tagatatttc tgattttgga gagttatcca tcagtttttg cacatattta cctaagatat
    12301 cattttcaag atttactgta ctcccgactt gtttactctt aagaatggtt tgttccaagg
    12361 tatgagggat aacagatact gaaaagttta ctttggagac tttagcgaca gtcagactaa
    12421 tgccgtcaat tgtaatagat cctttttcaa ctattaaatc taaaatttct ttttgtgtgt
    12481 tgatttgata ccatacagca ttatcatctt tttttattga cgagattttt cctgtaccat
    12541 caatgtgtcc tgtaacgacg tgacccccaa gtcgaccgtt gacagataag gctctttcta
    12601 gattcacctc acttccatgt tttaatagag taagagctgt tcgactccat gtttcattca
    12661 ttacatcaac tgtaaaggat tgatgattga aatgagtaac tgtaagacag ataccattta
    12721 ctgctatact atcgcctaaa tggatatccg ttaatatttt tgaggcttta attgatagtt
    12781 tacaattacg agagtctttc tgtattcttt caacttttcc gatttcttca attattcctg
    12841 tgaacatgga taaatcactt cactttctat gagatagtca tttcctattt gagaaaaagc
    12901 ataaggtttc aatctaatag cgtcatttgg caaagaaatg ccttcacctc cgacaggaaa
    12961 cttggcactg cctccaaaaa tttttggtgc aatatatatt ttcagctcat caacaatttg
    13021 ttgttccaaa gcactccaat tcattagact gcccccttct agaactaggc tatcaatctg
    13081 catgtttcct agatgttgca ttaaactcga taagtctata tgattgcctt ttttctttat
    13141 ggaaagtatt tcacagccat gattttgata tagcttcatt ttatttttgt cttcagagga
    13201 agtggcaatg taagttttaa tatcatttgc tgtttttacg attttagagg taagaggagt
    13261 tcgtaaatgt gtatcgcata tgatacggat aggatttttc ccttcctcca atctacatgt
    13321 cagcaaagga tcgtcttgaa taacagtatt gactcccacc ataattgcac taacatggtg
    13381 tcgtaactga tgcacatgct ttcttgcttc ttcttcagta atccatttgg attgatttgt
    13441 tttagtggct atttttccat ccattgacat tgcatatttc ataaaaacat agggtacatg
    13501 ctgggtaata tactttctaa aactttttat taagttaaga cactcatttt ctaaaattcc
    13561 aacagtaact tgaagattat tttcctcaag tatctttact ccttttccag atacaatagg
    13621 attacagtct aggcttccaa tgactactct tgtaatacca ctatcgatta tagcatctat
    13681 acagggaggt gttttcccga agtgacaaca gggttcaagt gttacataaa gcgtcgctcc
    13741 gacaggggat tctctacagt ttttaagagc atttctctca gcatgtgggc caccaaaaaa
    13801 ctcatgataa ccttgtccga tgatgtgatt atcttttaca ataactgcgc cgaccatagg
    13861 attgggattg acgtaaccag cccctttttg tgccagtttt attgctaatt tcatatattt
    13921 tgaatcgctc atctcactac ctccaaaaaa aatatacctt gaatagggga ctactcaagg
    13981 catacaaaag aaaacttatg cgattaacaa aaatactctg aaatgacaag taatcatttc
    14041 agagcacgca aaaagcacaa atatactttt atcttctttc atccagacta tactgtcggc
    14101 tttggaattt caccaaatca tgcctttcgg ctcgtgggct ataccaccgg tagggaatta
    14161 caccctgccc tgaagatagt tattcaatta cagatgatta tagtacttaa ttttgaatat
    14221 gtcaacagat aaataccgat tgtttttgat atactgtatt tgtgataatc gattctcgct
    14281 cctcggataa agaaaatatg atatactaga taaacgaaat aagagagaag gaatactatg
    14341 tacgcatatt taaaaggaat cattaccaaa attactgcca aatacattgt tcttgaaacc
    14401 aatggtattg gttatatcct gcatgtggcc aatccttatg cctattcagg tcaggttaat
    14461 caggaggctc agatttatgt gcatcaggtt gtgcgtgagg acgcccattt gctttatgga
    14521 tttcgctcag aggatgagaa aaagctcttt cttagtctga tttcggtctc tgggattggt
    14581 cctgtatcag ctcttgctat tatcgctgct gatgacaatg ctggcttggt tcaagccatt
    14641 gaaaccaaga acatcaccta cttgaccaag ttccctaaaa ttggcaagaa aacagcccag
    14701 cagatggtgc tggacttgga aggcaaggta gtagttgcag gagatggcct tcctgccaag
    14761 gtcgcagtgc aagcaagtgc tgaaaaccaa gaattggaag aagctatgga agccatgttg
    14821 gctctgggct acaaggcaac agagctcaag aaaatcaaga aattctttga aggaacgaca
    14881 gatacagctg agaactatat caagtcggcc cttaaaatgt tggtcaaata ggagcagaga
    14941 atgacaaaac gttgttcgtg ggtcaagatg accaacccac tctacatcgc ctatcatgat
    15001 gaggagtggg gccagcccct ccatgatgac caagcgttgt ttgagttatt gtgtatggaa
    15061 acctatcagg caggcctgtc ttgggaaacg gtactcaaca aacgccaagc tttccgagaa
    15121 gcctttcata gctatcaaat tcactcagtc gcagagatga ctgacactga attggaagcc
    15181 atgctggaga atccagctat cattcgaaat agagccaaga tttttgctac acgcgctaac
    15241 gcccaagctt ttctacagtt acaggcagag tacggctctt ttgatgccta tctttggtct
    15301 tttgttgagg ggaaaactgt cgttaacgat gttcctgatt atcgccaagc cccagctaaa
    15361 acacccttat ctgagaaatt agccaaagat ctcaaaaaac gagacttcaa gttcacaggc
    15421 ccagtcgccg tattgtcttt tctacaggct gcagggctag ttgatgacca cgagaatgat
    15481 tgtgagtgga aaggtcttaa atgatgtcta acaaaaataa gggaattctg atttttgcga
    15541 ttctctatac agtcctcttt gtgtttgatg gcgttaaatt gctggcttct ttaatgccat
    15601 ctgccattgc aaattatctt gtttatgtag ttttagctct atatggctcc ttcttattca
    15661 aggatagatt gatccaacaa tggaaggaga ttagaaagac taaaagaaaa ttcttctttg
    15721 gcgtcttaac aggatggctc tttctcattc tgatgactgt tgtctttgaa tttgtatcag
    15781 agatgttgaa gcagtttgtg gggctagtcg gacaaggtct aaatcagtct aatattcaaa
    15841 gcacttttca agagcaacca ctactgatag ctgtttttgc ttgtgtcatt ggacctctgg
    15901 tagaagaatt atttttccgt caggtcttat tgcattactt gcaggaacgg ttgccaggtt
    15961 tactaagcat tattctggta ggacttgttt ttgctctgac tcatatgcac agtttggctc
    16021 tatcagagtg gattggtgca gttggttact taggtggagg ccttgccttt tctattattt
    16081 atgtgaaaga aaaagagaat atctactatc cactacttgt tcacatgtta agcaacagcc
    16141 tctccttaat cattttagct atcagtatag taaaatgaaa taagaacagg acagtcaaat
    16201 cgatttctaa caatgtttta gaagtagatg tgtactattc tagtttcaat ttgctgtaat
    16261 atgtgatgaa aatgccagta atgataccga gaaaaaagct gagaaacttt tcccagcttt
    16321 atttgttata gtcaaagcga atgacttgtt cctgtgcatc tacatgagca tggaccccaa
    16381 agggtacaat tgctcttgga gttgcgtggc cggcattcag attatagaca atcgggatat
    16441 tgctgtcaat gatatccaat agtgcctctt tatagtcgtc atggaaagtt tcatccatag
    16501 gttttccgac caagagtcca ttgatgaccg cgaatatgcc agtgtccttt aaagttagca
    16561 acatcttttt gaagtcttct ggcttaggct tttcttcgct tgtttcgagc aagaggattt
    16621 tcccttccca gtctgacaag tcagggaaaa gtttgtattt ttggcagagc tccgtgctat
    16681 ctgcgtatcg agagttgtca aagatatcgt agagggattc gaggcaacca ccgaggattt
    16741 tcccctcgaa tagtgccctt ccttgcaaca agtcaaaacc tgtatttgta tgactgacac
    16801 gaggtgttcc cagggccgtg ggactaaaat cagttcgttc ctcataccaa acgtcactag
    16861 ggcggatttc tgaaattctt cccgtctcaa tcaattcttt aaagtagtga aggctatagg
    16921 ctagcatttc tttgtctaat tcacaaatgt ctgctaaaaa ggattgacca taaaaagtct
    16981 tgattcctaa tttatgcaac atgaggtggt tcatggttgt atccgagaag ccaagaaaaa
    17041 ttttttgctt gataaccttt tggagttggt cattttcaaa aagataaggt agcaagcgat
    17101 aggtatcgtc tccaccgatg gcacatagga tcatgtcgat gctatcatca gaaaaggcat
    17161 gaatcaaatc ctctgcacga gcttcaggat ggtccttgat aaagtctaat ccttttaacg
    17221 aatggggcaa aaagatggga ttgagtccca gatccttgag acgttggata cccaagtcca
    17281 cttcgtgttt gacaaaatcc tctccgataa tgccactaga taaactaaca ataccaatag
    17341 tagaaaccat atctcatcct cctagaaata gattgagcct attttatcac aaaatataag
    17401 agaaagctat gtgggatttc agaagaatac ttttaatact cttcgaaaat ctcttcaaac
    17461 cacgtcagtt ttatctgcaa cctcaaagct gtgctttgag caacctgcag ctagcttcct
    17521 agtttgctct ttgattttca ttgagtataa ctcaaaaaag taagtgaaaa agcaaccgca
    17581 cctgcagttg cttttatcgt tttcttattc ttgatagcgt gttggtcctg cacttgcact
    17641 acggatattc aagcgtttct tgagatagaa gcgaagggct aggagggctg ctccaataat
    17701 agctagtggc aatggatcca gtactgggtt aaggctagct ggtaggaagc ttgttgcaaa
    17761 gaagacaagc aaccaaagga acacagaagc taggataact agtacagatt tccagaaagg
    17821 tggacgttga ctgcgatcca tatctggtcc atagtattgg taaacaaagt agtacatcaa
    17881 gtagaaggca aatccaccaa ccagtccaac taatagaaga gtaatcaatc catagccgaa
    17941 agcttgatct gccgcaaaga aggttgtgag ggcgctgaca agggcaaaga ggctagtgat
    18001 gaaaagagct gagtccataa tcatcagttt tgggtcatca ttttcttttg gatgctcttt
    18061 ttcgtactgc tctttgacag tgaagctatg agcccaatga gttggtgcgc cgtataggga
    18121 acgggcagtt gtacctttag attgctcctc aaggatttgg ggaatgactt cctcaaaaat
    18181 agtctggatt tcagcgtctg ttttcccatc tttgatgaat tgttgggtag caatgtggac
    18241 aaactcttgg tttttcttag ttaatttttg tagatcaatt tgagacatag gaactccttt
    18301 tagaaccatt ttttatggat gagatagaga gtgagcgaga cactcatagc aaaggcgata
    18361 aagacgatta accagaaggc atttggctct ccgtttaggg gaatttcatt atccttaaag
    18421 ttcatcccgt aggcagaaaa gaccatggtt gggatggaca tgacgatggt cacaagggcc
    18481 aaggttttca tgatgttgtt ctggttgtta gaaatgatag aggcaaaggt ctctgtcata
    18541 gaatgcaaga cgtttccata aatatctgcc atctcgatgg cctgttgggt ttcaatcagg
    18601 gtgtcttcaa gcaggtcttc gtcctcaagg tatttcttga tattgctggt tgaactggtc
    18661 aatttcttaa tcacgcgctc atttgttttg agggaggcct tgaaatagac gatagttttt
    18721 tccaattcca tgagctcaat caattcttca ttacgagttg attgatgcag ttgactttcg
    18781 atttgttcac tcttgcggtc gattgaacga agggctgtta ggtaaagctc tgcattgcga
    18841 taaagaattt gaaagataaa acgtgaacgc atgaaggtat agaaattacg caatcgacgg
    18901 ttgataaaga catcaaggac aggtagtggt tccaaacacg tagtgataat ggtttcctca
    18961 gtgatgataa taccaagcgg gatggttacg tagtaggtgc ggttatttct ttcctccgtg
    19021 accggcacgt ctacgataat cagggtatac tcgtcttcaa tggtaatacg agacatttct
    19081 tccgcatcga gcggtgctcg aaggtcggca atatcaatat cgaaggtgtt ggcgatttcg
    19141 agtgattcat tttgagtcgg attgacgaga ttgatccaag tacccggttc aagcgtatcg
    19201 atctctttaa attcagttgt tgtagagaga aaaacttgtt tcatatccct tatcctttct
    19261 catttttcag attttttcac actgtactat tatactacaa aatcggcctt ttgggtaata
    19321 gaatctcact ttttttggta taatggtaag caataatgga ctagaaagaa caaagatgca
    19381 agataaaatt gtcattcatg gggcgcgtgc ccataattta aaaaatattg atgtggagat
    19441 tccgcgagac aagttggttg tcgtgactgg cttgtcaggt tcagggaagt ccagtttggc
    19501 ttttgatacc ctctatgcgg agggacaacg tcgctatgta gagagtttgt ccgcctacgc
    19561 tcgtcagttc ttgggaaata tggaaaaacc agatgtagat gccattgatg gtctcagccc
    19621 agctatttct atcgaccaga aaacgactag caaaaaccct cgctcgacgg tgggaacaac
    19681 gactgaaatc aatgactatc tgcgtctcct ctacgcgcgt gtggggacgc cttactgtat
    19741 caacgggcat ggggctatca aggcttcttc tgtggagcaa atcgttgata aggttttgga
    19801 gttacctgaa cgccagcgct tgcagatctt gtctcctgtc atccgcaaga aaaaaggcca
    19861 acataagagt gttatcgaga aggttcagaa agacgggtat gttcgtgtcc gtgtggatgg
    19921 ggaagtctat gatgtgaccg aagtgccaga gttgtctaag agcaagcaac acaatatcga
    19981 tgtcgtggtt gaccgtattg ttatcaagga gggcattcgt agtcgtctct ttgattccat
    20041 tgaggctgcc cttcgtattg cagaaggtta tgtcattatc gacaccatgg acaactctga
    20101 gttgttgttc tctgagcatt atgcctgtcc agtttgtggt tttactgtcc cagagttaga
    20161 gcctcgtctc ttttctttca atgctccttt tggctcttgt agtgagtgtg acggcttggg
    20221 catcaagctg gaggtggata ctgatttggt agtgccaaat gccagcaaaa ccttacatga
    20281 gggagcgctg gcaccttgga atcctatctc atccaactac tatccaaaca tgctagagca
    20341 ggccatgacg gcttttggag tggctatgga taagcctttt gaggacttgt cagaagaaga
    20401 caagaacttg attctctacg gctcagatgg taagaaattc catttccact atgagaatga
    20461 atttggtggc gtgcgcgata tcgacattcc gtttgaggga gttatcaata atatcaaacg
    20521 tcgttaccat gaaaccaata gcgattacac tcgcactcag atgcgcctct acatgaatga
    20581 gctgacttgc ggaacctgtc acggttatcg tctcaatgac caggccttgt ctgtccgtgt
    20641 gggtggtgag caagggccac atatcggaga aatttcagac ctgtctatcg cagatcactt
    20701 ggacttggtg agccagttaa ctttgtctga aaatgaagcc atcattgctc gtcccattct
    20761 caaggaaatc aaggatcgtt tgaccttcct taataatgtg ggtcttaact atctaaccct
    20821 gtcacgttca gcaggaaccc tttcaggtgg ggaaagtcag cgcattcgtt tggcaaccca
    20881 gattggttcc aacctatcag gcgtcctcta tatcctagac gagccgtcaa tcggtcttca
    20941 ccagagagac aatgaccgcc tgattgccag tctgaaaaag atgcgtgact tgggcaatac
    21001 tcttatcgtg gtggaacacg acgaagatac catgcgtgaa gctgattatc tgattgacgt
    21061 tggtcctggt gccggtgttt ttggtggtga gattgttgca gcaggtacac ctaagcaagt
    21121 ggctcgcaac agcaagtcta tcacaggtca gtacttgtca ggcaaacgtg tcatcccagt
    21181 accagaagag cgccgtgtcg gaaatggtcg ttttattgaa gtgataggag cgcgtgagaa
    21241 caacttgcaa aatgtcacgg ctcgctttcc actaggaaaa tttatcgcag tgacaggtgt
    21301 gtcgggttca gggaaatcga ctctaatcaa cagcattctc aaaaaagcca ttgcccagaa
    21361 gctcaaccgt aattcagaca aacctggtaa gtttaagact attacaggga ttgagcatgt
    21421 cgaccgtttg attgatattg accagagccc tatcggacgg acgccgaggt ctaacccagc
    21481 tacctataca ggagtttttg acgatatacg tgaccttttt gctcagacaa atgaagccaa
    21541 gattcgaggc tacaagaagg gacgcttcag tttcaacgtc aagggaggtc gctgtgaagc
    21601 ttgctcaggt gacgggatta tcaagattga gatgcacttc ttgccagatg tttatgtggc
    21661 ttgtgaagtt tgccacggaa cccgctataa cagtgaaacc ctagaagttc actacaagga
    21721 aaagaatatt tcgcaggtct tggatatgac ggtcaacgat gcggtagaat ttttccaaca
    21781 cattccgaaa attcaacgca aactccagac catcaaggat gtagggctag gctatgtgac
    21841 cttgggacag ccagctacca ccctttctgg gggagaagcc caacgtatga agttagctag
    21901 cgaactccac aaacgctcga caggaaaatc tttctacatt ctggatgaac cgacgacagg
    21961 gcttcataca gaggacattg ctcgcctgct caaggtttta gctcgctttg tagacgatgg
    22021 caatacagtc ctcgtcatcg agcacaatct ggatgttatc aagacggcag accatatcat
    22081 tgacttggga cctgagggcg gtgtcggtgg tggaaccatc atcgtaacag gaactccaga
    22141 agaagtagct gccaacgaag ccagctatac aggacactat ttgaaaggaa agttacatca
    22201 tgaataaacg cgtacaagca tttctagcta aaatgcaaga aaaagaacta gatggtgtca
    22261 tcatcaacaa tcttaaaaac gtctattatt tgactggttt ttggggctca aacggaacag
    22321 tctttatcag ccgtgaccgt caggtattag tgacagactc tcgctatatc atcgcagcta
    22381 agcaagaaac cagtggtttt gagattgtgg ctgatcgtga tgaattggct gtcattgcag
    22441 gaattgttaa ggacatgggc ttgactcgta tcggttttga agatgagatt tcagtgtctt
    22501 attaccaccg tatgcaggca gcttttgcag gtttgaactt gcttccacaa actcagtttg
    22561 tggaaggtct tcgtatgatt aaggatgagg cagagattgc agcgattcgc aaggcttgtt
    22621 ctatctcaga ccaagctttc cgcgatgcgc ttgactttat caaaccagga aaaactgaaa
    22681 ttgagattgc caacttcctt gatttccgca tgcgtgagtt gggagcatct ggcttatctt
    22741 ttgatacgat cctagctagc ggtatcaatt cttctaaacc ccatgcccat ccaatgcaca
    22801 aaccagtgga gttgggagaa gccattacca tggacttcgg ctgtctctat gaccactatg
    22861 tcagtgatat gacccggact atctatctag ggcatgttag cgatgagcag gcagagattt
    22921 acaatacggt tctaaaagct aaccaagcct tgattgacca agctaaggca ggcttaggtt
    22981 tccgtgactt tgacaaaatc cctcgtgata ttatcattga ggcaggttat ggtgactact
    23041 ttactcacgg cattggccac ggtattggtc tggatatcca tgaggaaccc tactttagtc
    23101 agacttctac agaaactatt aagacaggta tggccttgac cgatgaacca ggtatctata
    23161 tcgaaggcaa atatggcgtt cgtatcgagg atgatatcct gattacagag acaggttgtg
    23221 aattattgac cctagctcca aaagagttga tagtcattta gttgtttgtc aagaaaaaag
    23281 tacgaaaatg acgaaaaaag tcaaaaaaaa tt
//
LOCUS       DAVBBO010000032        22314 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ST1
            SAMEA2066453-rid20184263.denovo.032, whole genome shotgun sequence.
ACCESSION   DAVBBO010000032 DAVBBO010000000
VERSION     DAVBBO010000032.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2066453
            Sequence Read Archive: ERR351777
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 22314)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 22314)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980402.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980402.1
            Genome Coverage       :: 176x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:17:33
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,141
            CDSs (total)                      :: 2,104
            Genes (coding)                    :: 1,953
            CDSs (with protein)               :: 1,953
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 16S)
            partial rRNAs                     :: 1 (23S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 151
            CDSs (without protein)            :: 151
            Pseudo Genes (ambiguous residues) :: 0 of 151
            Pseudo Genes (frameshifted)       :: 73 of 151
            Pseudo Genes (incomplete)         :: 76 of 151
            Pseudo Genes (internal stop)      :: 40 of 151
            Pseudo Genes (multiple problems)  :: 32 of 151
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..22314
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2066453-rid20184263.denovo.032"
                     /strain="ST1"
                     /db_xref="taxon:1313"
     gene            complement(160..2118)
                     /gene="ftsH"
                     /locus_tag="VQU30_001261"
     CDS             complement(160..2118)
                     /gene="ftsH"
                     /locus_tag="VQU30_001261"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000744538.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent zinc metalloprotease FtsH"
                     /protein_id="HET2447373.1"
                     /translation="MKKQNNGLIKNPFLWLLFIFFLVTGFQYFYSGNNSGGSQQINYT
                     ELVQEITDGNVKELTYQPNGSVIEVSGVYKNPKTSKEETGIQFFTPSVTKVEKFTSTI
                     LPADTTVSELQKLATDHKAEVTVKHESSSGIWINLLVSIVPFGILFFFLFSMMGNMGG
                     GNGRNPMSFGRSKAKAANKEDIKVRFSDVAGAEEEKQELVEVVEFLKDPKRFTKLGAR
                     IPAGVLLEGPPGTGKTLLAKAVAGEAGVPFFSISGSDFVEMFVGVGASRVRSLFEDAK
                     KAAPAIIFIDEIDAVGRQRGVGLGGGNDEREQTLNQLLIEMDGFEGNEGIIVIAATNR
                     SDVLDPALLRPGRFDRKVLVGRPDVKGREAILKVHAKNKPLAEDVDLKLVAQQTPGFV
                     GADLENVLNEAALVAARRNKSIIDASDIDEAEDRVIAGPSKKDKTVSQKERELVAYHE
                     AGHTIVGLVLSNARVVHKVTIVPRGRAGGYMIALPKEDQMLLSKEDMKEQLAGLMGGR
                     VAEEIIFNVQTTGASNDFEQATQMARAMVTEYGMSEKLGPVQYEGNHAMFGAQSPQKS
                     ISEQTAYEIDEEVRSLLNEARNKAAEIIQSNREIHKLIAEALLKYETLDSTQIKALYE
                     TGKMPEAVEEESHALSYDEVKSKMNDEK"
     gene            complement(2134..2676)
                     /gene="hpt"
                     /locus_tag="VQU30_001262"
     CDS             complement(2134..2676)
                     /gene="hpt"
                     /locus_tag="VQU30_001262"
                     /EC_number="2.4.2.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypoxanthine phosphoribosyltransferase"
                     /protein_id="HET2447374.1"
                     /translation="MLENDIKKVLVSHDEITEAAKKLGAQLTKDYAGKNPILVGILKG
                     SIPFMAELVKHIDTHIEMDFMMVSSYHGGTASSGVINIKQDVTQDIKGRHVLFVEDII
                     DTGQTLKNLRDMFKAREAASVKIATLLDKPEGRVVEIEADYTCFTIPNEFVVGYGLDY
                     KENYRNLPYIGVLKEEVYSN"
     gene            complement(2680..3957)
                     /gene="tilS"
                     /locus_tag="VQU30_001263"
     CDS             complement(2680..3957)
                     /gene="tilS"
                     /locus_tag="VQU30_001263"
                     /EC_number="6.3.4.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269826.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA lysidine(34) synthetase TilS"
                     /protein_id="HET2447375.1"
                     /translation="MREPDFLNHFLKKGYFKKHAKAVLALSGGLDSMFLFKVLSTYQK
                     ELEIELILAHVNHKQRIESDWEEKELRKLAAEAELPIYISNFSGEFSEARARNFRYDF
                     FQEVMKKTGATALVTAHHADDQVETILMRLIRGTRLRYLSGIKEKQVVGEIEIIRPFL
                     HFQKKDFPSIFHFEDTSNQENHYFRNRIRNSYLPELEKENPRFRDAILGIGNEILDYD
                     LAIAELSNNINVEDLQQLFSYSESTQRVLLQTYLNRFPDLNLTKAQFAEVQQILKSKS
                     QYRHPIKNGYELIKEYQQFQICKISPQADEEEDELVLHYQNQVAYQGYLFSFGLPLEG
                     ESIQQIPVSRETSIHIRHRKTGDVLIQNGHRKKLRRLFIDLKIPMEKRNSALIIEQFG
                     EIVSILGIATNNLSKKTKNDIMNTVLYIEKIDR"
     gene            complement(3954..5222)
                     /locus_tag="VQU30_001264"
     CDS             complement(3954..5222)
                     /locus_tag="VQU30_001264"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001224749.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class A beta-lactamase-related serine hydrolase"
                     /protein_id="HET2447376.1"
                     /translation="MRKFLIILLLPSFLTISKVVSTEKEVVYTSKEIYYLSQSDFGIY
                     FREKLSSPMVYGEVPVYANEDLVVESGKLTPKTSFQITEWRLNKQGIPVFKLSNHQFI
                     AADKRFLYDQSEVTPTIKKAWLESDFKLYNSPYDLKEVKSSLSAYSQVSIDKTMFVEG
                     REFLHIDQAGWVAKESTSEEDNRMSKVQEMLSEKYQKDSFSIYVKQLTTGKEAGINQD
                     EKMYAASVLKLSYLYYTQEKINEGLYQLDTTVKYVSAVNDFPGSYKPEGSGSLPKKED
                     NKEYSLKDLITKVSKESDNVAHNLLGYYISNQSDATFKSKMSAIMGDDWDPKEKLISS
                     KMAGKFMEAIYNQNGFVLESLTKTDFDSQRIAKGVSVKVAHKIGDADEFKHDTGVVYA
                     DSPFILSIFTKNSDYDTISKIAKDVYEVLK"
     gene            complement(5342..5710)
                     /locus_tag="VQU30_001265"
     CDS             complement(5342..5710)
                     /locus_tag="VQU30_001265"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397271.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="septum formation initiator family protein"
                     /protein_id="HET2447377.1"
                     /translation="MSKNIVQLNNSFIQNEYQRRRYLMKERQKRNRFMGGVLILIMLL
                     FILPTFNLAQSYQQLLQRRQQLADLQTQYQTLSDEKDKETAFATKLKDEDYAAKYTRA
                     KYYYSKSREKVYTIPDLLQR"
     gene            complement(5703..5969)
                     /locus_tag="VQU30_001266"
     CDS             complement(5703..5969)
                     /locus_tag="VQU30_001266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001234972.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding S4 domain-containing protein"
                     /protein_id="HET2447378.1"
                     /translation="MRLDKYLKVSRIIKRRTVAKEVADKGRIKVNGILAKSSTDLKVN
                     DQVEIRFGNKLLLVKVLEMKDSTKKEDAAGMYEIISETRVEENV"
     gene            complement(6027..9536)
                     /gene="mfd"
                     /locus_tag="VQU30_001267"
     CDS             complement(6027..9536)
                     /gene="mfd"
                     /locus_tag="VQU30_001267"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000258090.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription-repair coupling factor"
                     /protein_id="HET2447379.1"
                     /translation="MVTLLDLFSENDQIKKWHQNLTDKKRQLILGLSTSTKALAIASS
                     LEKEDRIVLLTSTYGEAEGLVSDLISILGEELVYPFLVDDAPMVEFLMSSQEKIISRV
                     EALRFLTDSSKKGILVCNIAASRLILPSPNAFKDSIVKISVGEEYAQHAFIHQLKENG
                     YQKVTQVQTQGEFSLRGDILDIFEISQLEPCRIEFFGDEIDGIRSFEVETQLSKENKT
                     ELTIFPASDMLLREKDYQRGQSALEKQISKTLSPILKSYLEEILSSFHQKQSHADSRK
                     FLSLCYDKTWTVFDYIEKDTPIFFDDYQKLMNQYEVFERELAQYFTEELQNSKAFSDM
                     QYFSDIEQIYKKQSPVTFFSNLQKGLGNLKFDKIYQFNQYPIQEFFNQFSFLKEEIER
                     YKKMDYTIILQSSNSMGSKTLEDMLEEYQIKLDSRDKTSICKESVNLIEGNLRHGFHF
                     VDEKILLITEHEIFQKKLKRRFRRQHVSNAERLKDYNELEKGDYVVHHIHGIGQYLGI
                     ETIEIKGIHRDYVSVQYQNGDQISIPVEQIHLLSKYISSDGKAPKLNKLNDGHFKKAK
                     QKVKNQVEDIADDLIKLYSERSQLKGFAFSADDDDQDAFDDAFPYVETDDQLRSIEEI
                     KRDMQASQPMDRLLVGDVGFGKTEVAMRAAFKAVNDHKQVVILVPTTVLAQQHYTNFK
                     ERFQNFAVNIDVLSRFRSKKEQTATLEKLKNGQVDILIGTHRVLSKDVVFADLGLMII
                     DEEQRFGVKHKETLKELKKQVDVLTLTATPIPRTLHMSMLGIRDLSVIETPPTNRYPV
                     QTYVLEKNDSVIRDAVLREMERGGQVYYLYNKVDTIVQKVSELQELIPEASIGYVHGR
                     MSEVQLENTLLDFIEGQYDILVTTTIIETGVDIPNANTLFIENADHMGLSTLYQLRGR
                     VGRSNRIAYAYLMYRPEKSISEVSEKRLEAIKGFTELGSGFKIAMRDLSIRGAGNLLG
                     KSQSGFIDSVGFELYSQLLEEAIAKRNGNANANTRTKGNAELILQIDAYLPDTYISDQ
                     RHKIEIYKKIRQIDNRVNYEELQEELIDRFGEYPDVVAYLLEIGLVKSYLDKVFVQRV
                     ERKDNKITIQFEKVTQRLFLAQDYFKALSVTNLKAGIAENKGLMELVFDVQNKKDYEI
                     LEGLLIFGESLLEIKEFKEENSI"
     gene            complement(9537..10106)
                     /locus_tag="VQU30_001268"
     CDS             complement(9537..10106)
                     /locus_tag="VQU30_001268"
                     /EC_number="3.1.1.29"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000163933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoacyl-tRNA hydrolase"
                     /protein_id="HET2447380.1"
                     /translation="MTKLLVGLGNPGDKYFETKHNVGFMLIDQLAKKQNVTFTHDKIF
                     QADLASFFLNGEKIYLVKPTTFMNESGKAVHALLTYYGLDIDDLLIIYDDLDMEVGKI
                     RLRAKGSAGGHNGIKSIIQHIGTQVFNRVKIGIGRPKNGMSVVHHVLSKFDRDDYIGI
                     LQSVDKVDDSVKYYLQEKNFEKTMQRYNG"
     gene            complement(10177..11292)
                     /gene="ychF"
                     /locus_tag="VQU30_001269"
     CDS             complement(10177..11292)
                     /gene="ychF"
                     /locus_tag="VQU30_001269"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002269933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="redox-regulated ATPase YchF"
                     /protein_id="HET2447381.1"
                     /translation="MALTAGIVGLPNVGKSTLFNAITKAGAEAANYPFATIDPNVGMV
                     EVPDERLQKLTEMITPKKTVPTTFEFTDIAGIVKGASKGEGLGNKFLANIREVDAIVH
                     VVRAFDDENVMREQGREDAFVDPLADIDTINLELILADLESVNKRYARVEKMARTQKD
                     KESVAEFNVLQKIKPVLEDGKSARTIEFTDEEQKVVKGLFLLTTKPVLYVANVDEDVV
                     SEPDSIDYVKQIREFAATENAEVVVISARAEEEISELDDEDKKEFLEAIGLTESGVDK
                     LTRAAYHLLGLGTYFTAGEKEVRAWTFKRGMKAPQAAGIIHSDFEKGFIRAVTMSYED
                     LVKYGSEKAVKEAGRLREEGKEYIVQDGDIIEFRFNV"
     gene            complement(11376..11570)
                     /locus_tag="VQU30_001270"
     CDS             complement(11376..11570)
                     /locus_tag="VQU30_001270"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF951 family protein"
                     /protein_id="HET2447382.1"
                     /translation="MYQVGNFVEMKKSHACTIKSTGKKANRWEITRVGADIKIKCSNC
                     EHVVMMGRYDFERKMNKIID"
     gene            complement(11635..12771)
                     /gene="dnaN"
                     /locus_tag="VQU30_001271"
     CDS             complement(11635..12771)
                     /gene="dnaN"
                     /locus_tag="VQU30_001271"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000581170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit beta"
                     /protein_id="HET2447383.1"
                     /translation="MIHFSINKNLFLQALNTTKRAISSKNAIPILSTVKIDVTNEGIT
                     LIGSNGQISIENFISQKNEDAGLLITSLGSILLEASFFINVVSSLPDVTLDFKEIEQN
                     QIVLTSGKSEITLKGKDSEQYPRIQEISASTPLILETKLLKKIINETAFAASTQESRP
                     ILTGVHFVLSQHKELKTVATDSHRLSQKKLTLEKNSDDFDVVIPSRSLREFSAVFTDD
                     IETVEIFFANNQILFRSENISFYTRLLEGNYPDTDRLIPTDFNTTITFNVVNLRQSME
                     RARLLSSATQNGTVKLEIKDGVVSAHVHSPEVGKVNEEIDTDQVTGEDLTISFNPTYL
                     IDSLKALNSEKVTISFISAVRPFTLVPADTDEDFMQLITPVRTN"
     gene            complement(12930..14291)
                     /gene="dnaA"
                     /locus_tag="VQU30_001272"
     CDS             complement(12930..14291)
                     /gene="dnaA"
                     /locus_tag="VQU30_001272"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255267.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chromosomal replication initiator protein DnaA"
                     /protein_id="HET2447384.1"
                     /translation="MKEKQFWNRILEFAQERLTRSMYDFYAIQAELIKVEENVATIFL
                     PRSEMEMVWEKQLKDIIVVAGFEIYDAEITPHYIFTKPQDTTSSQVEEATNLTLYNYS
                     PKLVSIPYSDTGLKEKYTFDNFIQGDGNVWAVSAALAVSEDLALTYNPLFIYGGPGLG
                     KTHLLNAIGNEILKNIPNARVKYIPAESFINDFLDHLRLGEMEKFKKTYRSLDLLLID
                     DIQSLSGKKVATQEEFFNTFNALHDKQKQIVLTSDRSPKHLEGLEERLVTRFSWGLTQ
                     TITPPDFETRIAILQSKTEHLGYNFQSDTLEYLAGQFDSNVRDLEGAINDITLIARVK
                     KIKDITIDIAAEAIRARKQDVSQMLVIPIDKIQTEVGNFYGVSIKEMKGSRRLQNIVL
                     ARQVAMYLSRELTDNSLPKIGKEFGGKDHTTVIHAHAKIKSLIDQDDNLRLEIESIKK
                     KIK"
     gene            complement(14504..15262)
                     /locus_tag="VQU30_001273"
     CDS             complement(14504..15262)
                     /locus_tag="VQU30_001273"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000410347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParB/RepB/Spo0J family partition protein"
                     /protein_id="HET2447385.1"
                     /translation="MEKFEMISITDIQKNPYQPRKEFDREKLDELAQSIKENGVIQPI
                     IVRQSPVIGYEILAGERRYRASLLAGLRSIPAVVKQISDQEMMVQSIIENLQRENLNP
                     IEEARAYESLVEKGFTHAEIADKMGKSRPYISNSIRLLSLPEQILSEVENGKLSQAHA
                     RSLVGLNKEQQDYFFQRIIEEDISVRKLEALLTEKKQKKQQKTNHFIQNEEKQLRKLL
                     GLDVEIKLSKKDSGKIIISFSNQEEYSRIINSLK"
     gene            complement(15320..16501)
                     /locus_tag="VQU30_001274"
     CDS             complement(15320..16501)
                     /locus_tag="VQU30_001274"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000681590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine protease"
                     /protein_id="HET2447386.1"
                     /translation="MKHLKTFYKKWFQLLVVIVISFFSGALGSFSITQLTQKSSVNNS
                     NNNSTITQTAYKNENSTTQAVNKVKDAVVSVITYSANRQNSVFGNDDTDTDSQRISSE
                     GSGVIYKKNDKEAYIVTNNHVINGASKVDIRLSDGTKVPGEIVGADTFSDIAVVKISS
                     EKVTTVAEFGDSSKLTVGETAIAIGSPLGSEYANTVTQGIVSSLNRNVSLKSEDGQAI
                     STKAIQTDTAINPGNSGGPLINIQGQVIGITSSKIATNGGTSVEGLGFAIPANDAINI
                     IEQLEKNGKVTRPALGIQMVNLSNVSTSDIRRLNIPSNVTSGVVVRSVQSNMPANGHL
                     EKYDVITKVDDKEIASSTDLQSALYNHSIGDTIKITYYRNGKEETTSIKLNKSSGDLE
                     S"
     gene            16684..17163
                     /gene="rlmH"
                     /locus_tag="VQU30_001275"
     CDS             16684..17163
                     /gene="rlmH"
                     /locus_tag="VQU30_001275"
                     /EC_number="2.1.1.177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000695929.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA
                     (pseudouridine(1915)-N(3))-methyltransferase RlmH"
                     /protein_id="HET2447387.1"
                     /translation="MKIKVVTVGKLKEKYLKDGIAEYSKRISRFAKFEMIELSDEKTP
                     DKASESENQKILEIEGQRILSKIADRDFVIVLAIEGKTFFSEEFSKQLEETSIKGFST
                     LTFIIGGSLGLSSSVKNRANLSVSFGRLTLPHQLMRLVLVEQIYRAFTIQQGFPYHK"
     gene            17207..17280
                     /locus_tag="VQU30_001276"
     tRNA            17207..17280
                     /locus_tag="VQU30_001276"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:17241..17243,aa:Arg,seq:tct)
     gene            17445..17570
                     /gene="comC"
                     /locus_tag="VQU30_001277"
     CDS             17445..17570
                     /gene="comC"
                     /locus_tag="VQU30_001277"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000799689.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence-stimulating peptide ComC"
                     /protein_id="HET2447388.1"
                     /translation="MKNTVKLEQFVALKEKDLQKIKGGEMRLSKFFRDFILQRKK"
     gene            17591..18916
                     /locus_tag="VQU30_001278"
     CDS             17591..18916
                     /locus_tag="VQU30_001278"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000362880.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HET2447389.1"
                     /translation="MDLFGFGTVIVHFLIISHSYHFICKGQINRKELFVFGAYTLLTE
                     IVFDFPLYILYLDGLGIERFLFPLGLYSYFRWMKQYERDRGLFLSLLLSLLYESTHNF
                     LSVTFSSITGDNFVLQYHFPFFFVVTVLTYFVTLKIIYYFHLELAYFDEDYLYPFLKK
                     VFFALLLLHIVSFVSDMVSTIKHLNSFGSILSSIVFISLLLTFFAMNSHKVQMEKEIA
                     LKQKKFEQKHLQNYTDEIVGLYNEIRGFRHDYAGMLVSMQMAIDSGNLQEIDRIYNEV
                     LVKANHKLRSDKYTYFDLNNIEDSALRSLVAQSIVYARNNGVEFTLEVKDTITKLPIE
                     LLDLVRIMSVLLNNAVEGSADSYKKQMEVAVIKMETETVIVIQNSCKMTMTPSGDLFA
                     LGFSTKGRNRGVGLNNVKELLDKYNNIILETEMEGSTFRQIIRFKREFE"
     gene            18913..19665
                     /locus_tag="VQU30_001279"
     CDS             18913..19665
                     /locus_tag="VQU30_001279"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000866085.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HET2447390.1"
                     /translation="MKVLILEDVIEHQVRLERILDEISKESNIPISYKTTGKVREFEE
                     YIENDEVNQLYFLDIDIHGIEKKGFEVAQLIRHYNPYAIIVFITSRSEFATLTYKYQV
                     SALDFVDKDINDEMFKKRIEQNIFYTKSMLLENEDVVDYFDYNYKGNDLKIPYHDILY
                     IETTGVSHKLRIIGKNFAKEFYGTMTDIQEKDKHTQRFYSPHKSFLVNIGNIREIDRK
                     NLEIVFYEDHRCPISRLKIRKLKDILEKKSQK"
     gene            19717..19788
                     /locus_tag="VQU30_001280"
     tRNA            19717..19788
                     /locus_tag="VQU30_001280"
                     /product="tRNA-Glu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:19750..19752,aa:Glu,seq:ttc)
     gene            19794..19867
                     /locus_tag="VQU30_001281"
     tRNA            19794..19867
                     /locus_tag="VQU30_001281"
                     /product="tRNA-Asn"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:19828..19830,aa:Asn,seq:gtt)
     gene            complement(19908..20450)
                     /locus_tag="VQU30_001282"
     CDS             complement(19908..20450)
                     /locus_tag="VQU30_001282"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399421.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator
                     C-terminal domain-containing protein"
                     /protein_id="HET2447391.1"
                     /translation="MQESNKRLKTKRTIENAMVQLLMEQPFDKISTVKLVEKAGISRS
                     SFYTHYKDKYDMIEHYQSKLFHTFEYIFQKHAHHKRDAILEVFEYLESEPLLAALLSE
                     NGTKEIQNFLRNKLHIMLSTDLQKRFMQLNLNTTELEYSSIYLTHALFGVCQTWIAHG
                     KKESSQEITDFLMKMLGDTN"
     gene            20629..21396
                     /locus_tag="VQU30_001283"
     CDS             20629..21396
                     /locus_tag="VQU30_001283"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhgE/Pip domain-containing protein"
                     /protein_id="HET2447392.1"
                     /translation="MIGISLIPDLYNIIFLSSMWDPYGQLSDLPVAVVNNDKEASYNG
                     NTMAIGKDMVSNLKENKTLDFHFVDEEEGKKGLEDGDYYMVVTLPSDLSEKTTTLSNI
                     QSTAAYQSLTSEQQTEISDSVSQNSTDSIQSAQSIVALVQDLQGSLENLQNQSSNLST
                     LKNQSNQVSPITSTSLIGLSSGLTEIQGDVTSKLVPASQSIASGVNAYTTGVDKVSQG
                     ASQLSEKNATLTGSLDKLVSGSNTLTQKSSRLTAGVG"
     gene            21481..22161
                     /locus_tag="VQU30_001284"
     CDS             21481..22161
                     /locus_tag="VQU30_001284"
                     /inference="COORDINATES: protein motif:HMM:TIGR03057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhgE/Pip family protein"
                     /protein_id="HET2447393.1"
                     /translation="MADGSGKLAEGGTKLTSGLEDLQTGLASLGQGLGNASDQLKSVS
                     TESKNAEILSNPLNLSKTDNDQVPVNGIAIAPYMISVALFVAAISTNMIFAKLPSGRH
                     PESRWAWLKSRAEINGIIAVLAGILVYGGVQLIGLTANHEMRIFILIILTSLVFMSMV
                     TTLTTWNSRIGAFFLLILLLLQLASSAGTYPLALTNDFFRSINPWLPMSYSVSGLRQT
                     ISINKSFS"
BASE COUNT         6901 a         4110 c         3643 g         7660 t
ORIGIN      
        1 acagtccctt ggacttcttc atacaattct ttaatcataa ttttcccctt tctagataca
       61 gtctaacaga ttagaaaaca catttgttcc attttctcca ttctgttccc tttagctcct
      121 aaactgcaca aaaaagagag gctccagcct ctctcagggt tatttttcgt cattcatttt
      181 tgactttact tcatcatagg atagtgcatg agattcctct tctactgctt caggcatctt
      241 tcctgtttcg taaagagctt taatttgtgt actatccaat gtttcgtatt tcaataatgc
      301 ttctgcaatt aacttgtgaa tttcacgatt tgactgaata atttcagcag ctttatttcg
      361 tgcctcattt aataatgaac gaacctcttc atcaatttca taagctgttt gttctgaaat
      421 tgatttttga ggactctgtg caccaaacat agcatggttt ccttcatatt gtactgggcc
      481 aagtttttca ctcataccgt actctgtaac cattgcacgc gccatttgtg tcgcttgttc
      541 aaagtcgttt gaagctcctg tagtttggac attaaagata atttcttcag ctacacgtcc
      601 acccattaag ccagccaatt gctctttcat atcttcttta gatagaagca tttgatcctc
      661 tttaggaagt gcaatcatgt atccgcctgc acggccgcgt ggtacaattg taaccttatg
      721 gacaacgcga gcattcgaca agactagacc aacaatggta tgtcctgcct catggtaagc
      781 aaccaattct cgttcttttt gtgaaactgt cttatctttc ttagaaggtc cagcaataac
      841 tctatcttct gcttcatcaa tatctgaagc atcaattatc gatttattgc gacgagcagc
      901 aactaaagct gcttcattca agacattctc taaatcagca ccaacaaagc ctggagtttg
      961 ttgagccact aatttcaaat caacatcttc tgctaaaggc ttgttcttag cgtgaacttt
     1021 caagattgct tcacgacctt taacatcagg acgaccaacc aatacttttc tatcaaaacg
     1081 tcctggacgc aaaagggcag gatcaagtac atctgaacgg tttgtcgcag cgatgacgat
     1141 aatcccttca tttccctcaa aaccatccat ctcaatcaaa agttggttca aggtttgttc
     1201 acgttcgtca ttacctccgc cgagaccgac tccacgttga cgtccaacag catcaatttc
     1261 atcgataaag atgatagctg gtgctgcttt tttggcatcc tcaaaaagag agcgaacacg
     1321 actagctcca actccgacaa acatttctac aaagtcagaa cctgagatac taaagaatgg
     1381 aacacctgct tctccagcga ctgccttagc aagcaaagtt ttacctgtcc ccggaggtcc
     1441 ctccaaaaga acacctgctg gaatacgggc tccaagtttt gtgaatcgtt ttggatcttt
     1501 taagaactca acaacttcaa ctagttcttg tttttcttcc tcagctccag caacatctga
     1561 aaatcttact ttaatatctt ctttatttgc tgctttagcc ttactacgtc caaaactcat
     1621 tggattacgg ccattgcctc ctcccatatt tcccatcata gagaatagga agaagaatag
     1681 aattccaaat ggcacaatgg atacgagtag attaatccat ataccacttg aactttcatg
     1741 cttaacagtt acttctgctt tatggtcagt agcaagtttt tgcaattctg atacggtagt
     1801 atctgcagga agaatagtgc tggtaaattt ctctacctta gtaacagatg gcgtgaaaaa
     1861 ctgaatacct gtttcttctt tacttgtttt aggattttta tagacaccag aaacttcgat
     1921 aacactacca tttggttggt aagttaattc ttttacatta ccatcggtaa tttcttgtac
     1981 caactcagta tagttgattt gctgacttcc tcctgagtta ttcccagaat agaaatactg
     2041 gaatcctgtc acaaggaaaa agataaataa taaccataga aaaggatttt taattaaacc
     2101 attattttgt tttttcatta aagattattc tttctaattt gaatacactt cctctttcaa
     2161 tactccaata taaggaagat tacgataatt ttctttgtag tctaaaccat aacctactac
     2221 aaactcattt gggatagtaa agcaggtata gtctgcctca atttctacaa cacgtccttc
     2281 tggtttatcc aacaaggttg caattttaac agaagctgct tctcttgctt taaacatatc
     2341 tcgcaaattc ttcaaagttt gacctgtatc aatgatatct tctacaaata gaacatgtct
     2401 tcctttgata tcttgagtca catcttgttt aatattgata acaccactac ttgctgttcc
     2461 accatggtag ctagaaacca tcatgaagtc catttcaata tgtgtatcaa tatgtttgac
     2521 caattcagcc ataaaaggaa tagatccttt taaaatccca actaagattg gattttttcc
     2581 tgcatagtct ttagttaatt gagcacctag ttttttagct gcttctgtaa tttcatcgtg
     2641 tgaaacgagg acttttttaa tatcgttttc taacattttt tacctatcta ttttttctat
     2701 ataaagtaca gtgttcatta tatcattttt cgttttttta ctcaaattat tggtcgcaat
     2761 tcccaaaatt gagacaattt caccaaattg ctcaataata agagcagagt ttctcttttc
     2821 catagggatt ttcaaatcaa taaataaacg tctgagtttt tttctatgcc cattttgaat
     2881 caaaacatct cctgtttttc gatgacgaat gtgtatggat gtttcacgtg aaacaggtat
     2941 ttgttgaatt gattcacctt ctaatggaag tccaaaggaa aataaatatc cttgataagc
     3001 tacctgattt tgatagtgta acacaagttc atcttcctct tcatcagcct gcggactgat
     3061 tttacaaatc tgaaactgtt ggtactcttt tatcaattca tagccatttt taatcggatg
     3121 acgatactgg cttttagatt ttaaaatctg ctgaacttca gcaaactgag cttttgtaag
     3181 attcaaatct ggaaaacgat tcagataagt ttgaagtaaa actctttgtg tagactcaga
     3241 gtaagaaaat aactgctgta aatcttccac attaatattg ttagataatt cagctattgc
     3301 caaatcataa tctaaaattt cattgccaat gcctaagatt gcatccctaa atcgaggatt
     3361 ttctttttcc aattctggta agtaagagtt tcgaatacga tttcgaaaat aatgattctc
     3421 ctgatttgat gtatcttcaa agtgaaaaat tgatggaaag tcttttttct gaaaatgcaa
     3481 gaagggacga atgatttcta tctctccgac tacttgcttc tccttaattc ctgatagata
     3541 gcgcaagcga gttcctcgaa tcaagcgcat caaaatcgtt tccacctgat catcagcatg
     3601 gtgggcagtg actaaagctg tcgcacctgt ctttttcatg acctcttgaa aaaaatcata
     3661 acgaaaattt cgtgcacgcg cttctgaaaa ttctcctgaa aaattgctga tataaatagg
     3721 aagctctgct tcagcagcca acttccttaa ttccttttct tcccaatctg attcaattct
     3781 ctgcttatga ttcacatgag ctagaatcaa ttcaatctct aactcttttt gataagtaga
     3841 caatacctta aatagaaaca tggaatctaa tccaccagaa agagctagaa ccgccttagc
     3901 atgctttttg aaatatccct tcttgagaaa atgatttaaa aaatctggtt ccctcatttt
     3961 agaacctcat aaacatcctt ggctatctta gaaatcgtat cataatcaga attcttagtg
     4021 aaaatagaaa gaataaatgg agaatctgca tagacaacac ccgtatcatg cttaaattca
     4081 tccgcatctc caattttatg agctacttta acagaaacac ctttggcaat tcgctgacta
     4141 tcaaaatctg ttttagtcaa agactctaac acaaatccat tttgattata aatagcttcc
     4201 ataaacttcc cggccatctt agaagaaatc aatttttctt ttggatccca atcatctccc
     4261 ataatggcag acatcttgga tttgaatgtg gcatcagatt ggtttgaaat gtaatatccc
     4321 aatagattat gagctacatt atcagattct tttgatactt tcgtaattaa atcctttaaa
     4381 gaatattctt tattatcttc ttttttagga agactaccac ttccctctgg tttataagaa
     4441 cctggaaaat cattgactgc agatacgtat tttacagtcg tatctaactg ataaagaccc
     4501 tcatttattt tttcttgcgt ataatagaga taagagagtt tcaaaacgct ggctgcatac
     4561 atcttttcat cttgattgat accagcttct tttccagtag tcagttgctt aacataaata
     4621 gagaaagaat ctttctgata tttttcagat aacatttctt gaactttact catccgatta
     4681 tcttcttcag aagttgattc tttagctacc catccagcct gatcaatatg tagaaattct
     4741 cttccttcta caaacatggt cttgtcgatt gatacttgcg aataagctga taaggatgat
     4801 ttcacttctt ttaaatcata aggactattg tacagtttaa agtcagattc taaccatgct
     4861 ttttttattg ttggagttac ctctgattga tcatataaaa atcgtttgtc cgcagctata
     4921 aattgatgat ttgatagctt aaatactgga attccttgtt tatttaagcg ccactcggtt
     4981 atttgaaaac ttgttttggg agtcaatttc ccagattcca ctactaaatc ttcattcgca
     5041 taaacaggaa cctctccata aaccatggga gaacttaatt tttctctaaa ataaatacca
     5101 aagtcagatt gtgaaaggta ataaatttct ttcgaagtat agacgacttc tttttctgtg
     5161 ctaacgactt ttgaaatggt caaaaaactt ggtagcaaca aaataattaa gaatttacgc
     5221 attcttcctt tccttttctt cttgtaaacg caataattga tttttatcag ccaattcttc
     5281 cagcttttca tctgacaaac tcaaaaattg ctctattacg tctaataaat tttccatttt
     5341 atcacctttg aagcaagtca ggaatcgtat aaactttttc cctcgactta gaataatagt
     5401 acttcgctcg tgtatatttg gcagcataat cttcatcttt caacttggta gcaaatgctg
     5461 tctccttatc cttttcatca ctcaaagttt gatactgagt ttgcaagtct gctaattgct
     5521 gacgtctttg gagtaattgc tgataactct gcgctaaatt aaaagttggc aagataaata
     5581 atagcataat caaaatcaat acccctccca taaaacgatt ccgtttttgt cgttctttca
     5641 tcaggtagcg acgacgttgg tattcatttt gaataaaaga attattcaat tgtacaatat
     5701 ttttagacat tttcttctac ccgtgtttca ctgataattt catacattcc tgctgcatct
     5761 tctttttttg tactatcttt catctctagt acttttacaa gcagcaactt attgccaaag
     5821 cgaatttcaa cttggtcatt aactttcaag tccgttgaac ttttggccaa gattccatta
     5881 accttgattc tacctttatc tgctacttcc tttgcgactg tacgacgctt gataattcgc
     5941 gatactttta aatatttatc taatctcatc cttattacct caatttatta ttgtaccatt
     6001 tttatctatt ttatagaaga aaaatatcaa atggaatttt cttccttaaa ctcttttatc
     6061 tctaataaac tttctccaaa aatcagcaga ccttctaaaa tttcataatc tttcttattt
     6121 tggacatcaa atacaagctc cattaatccc ttattctcag cgatgcctgc ttttaagttc
     6181 gttacggata aagctttaaa ataatcttga gctaaaaaca atcgttgagt gactttttca
     6241 aattgaattg taattttatt atcttttctt tccacacgtt gaacaaagac cttgtccaag
     6301 tatgatttaa ccaaaccaat ctctaaaaga taggctacta catctgggta ttctccaaaa
     6361 cggtctatca actcctcttg taactcttca taattgacac ggttgtcaat ttgacgaatt
     6421 ttcttgtaaa tttcaatctt atgtcgttga tcagaaatat aagtatcagg aagataggca
     6481 tcaatttgca aaatcaactc agcattccct ttggttcttg tgttagcgtt agcattaccg
     6541 tttcgtttag caatagcttc ctctaataac tgcgaataca attcaaaacc aacagaatca
     6601 atgaaaccag actgggattt tcctaaaaga tttcctgctc cacgaatcga aagatctcgc
     6661 attgcaatct taaagccaga gcccaattct gtaaatcctt taatcgcttc taatctcttt
     6721 tcagagactt cactgattga tttttctgga cgatacatga gataagcata agcaatacga
     6781 ttactacgac cgactcttcc tcttaactga tataaggttg acaagcccat atggtccgca
     6841 ttttcaataa ataaagtatt agcatttgga atgtccaccc ctgtctcaat aatagtagtc
     6901 gtcaccaaga tatcgtattg tccctcaata aagtctaata gagtattttc caactggact
     6961 tcactcattc gaccatgaac atatccaatc gaagcctccg gaatcaactc ctgtaattct
     7021 gaaaccttct gaacaattgt gtcaactttg ttgtaaagat aataaacttg acctccacgc
     7081 tccatttcac gcaagacagc atcacgaatg acactatcat tcttttccaa aacataggtc
     7141 tgaacaggat agcgattagt cggcggagtt tcaataacag ataaatctct gattcccagc
     7201 atagacatat ggagggtacg agggattggc gtagcggtca aggttaggac atccacttgt
     7261 ttcttcagtt ctttcaaagt ttccttatgc ttgacaccaa atcgctgttc ctcatcaata
     7321 atcatcaagc ccaaatcagc aaacacaaca tcttttgaca aaacacgatg tgttccaatc
     7381 aaaatatcga cttgaccgtt tttcaatttt tcaagtgttg cagtctgctc ttttttactt
     7441 ctaaagcgac tcaacacatc aatattaact gcaaaatttt ggaatcgttc cttaaaattc
     7501 gtatagtgct gttgcgctaa aaccgtcgtc ggaactagaa tgacaacctg tttgtgatca
     7561 ttgactgctt taaaggctgc acgcatagca acttcagtct ttccaaaacc aacatcccca
     7621 actaaaagtc gatccattgg ctgagaagcc tgcatatccc tcttgatttc ctcaatacta
     7681 cgaagttgat catccgtttc aacataaggg aaagcatcat caaaggcatc ttgatcatca
     7741 tcatcagctg agaaagcaaa acccttcaac tgactacgtt cagagtagag tttgattaaa
     7801 tcatcagcta tatcctctac ctggttctta accttttgct tggccttttt aaaatgaccg
     7861 tcatttaatt tattgagttt tggagcttta ccatcacttg aaatatattt ggacagtaga
     7921 tgaatctgtt ccacggggat agaaatttga tcaccatttt ggtattggac actgacataa
     7981 tcgcgatgaa ttcccttgat ttcaatggtt tcaattccta gatattgacc aatcccatgg
     8041 atatgatgga caacatagtc ccctttttca agttcattgt aatcttttaa tctctctgca
     8101 tttgaaacat gttgtcttcg aaaacgacgc tttaatttct tttgaaaaat ctcatgttca
     8161 gttatcaata aaatcttttc atctacaaaa tgaaaaccat gtctgagatt accctctatt
     8221 aaatttacag attctttaca gatacttgtc ttatctctag aatccaattt aatctgatat
     8281 tcctctaaca tatcctccaa tgttttactt cccattgaat tgctagactg cagaataatg
     8341 gtgtaatcca tttttttata tcgttcaatt tcttctttta gaaaagaaaa ctgattgaaa
     8401 aattcctgta taggatattg attgaattga taaattttgt caaatttgag atttcctaaa
     8461 cccttttgaa gattagagaa aaaggtcact ggactttgtt ttttatagat ttgttcaata
     8521 tcagaaaaat actgcatatc agaaaatgct ttactattct gtaattcttc tgtaaagtac
     8581 tgcgctaatt ctctttcaaa gacttcatac tgattcatca atttttgata atcatcaaag
     8641 aatattggag tatctttttc aatataatca aagacagtcc atgtcttatc atagcacaaa
     8701 gataaaaact tccgagaatc tgcatgactt tgtttttggt gaaaacttga aagaatttct
     8761 tctaggtatg atttcaaaat aggtgataaa gtttttgaaa tttgtttttc taaagctgac
     8821 tgtcctcgtt gataatcctt ttctctcaaa agcatatcac tagctggaaa gatagtgagt
     8881 tctgtcttat tttctttcga taattgtgtt tctacttcaa atgacctgat accatcaatt
     8941 tcatcaccaa aaaactcaat tcgacaaggt tctaactggg atatttcaaa aatatctaaa
     9001 atatctcctc gaagactaaa ttcgccctga gtttgtactt gagtaacttt ttgatagcca
     9061 ttttccttta actgatggat aaacgcgtgt tgagcatatt cttcaccaac tgagattttt
     9121 acaatactat ctttgaatgc attgggagac ggtaaaatca atcgacttgc tgcgatatta
     9181 caaactaaaa tccctttctt agatgaatca gtcaaaaaac gcaaggcttc aacccgtgaa
     9241 ataatttttt cctgtgaaga catcaaaaac tccaccatag gagcatcatc taccaaaaat
     9301 ggatagacga gttcctcacc caagatagaa ataagatcac taacaagtcc ttctgcttct
     9361 ccataagttg acgtcaataa cacaatccta tcttcttttt ctaaactgct tgcaattgca
     9421 agagccttag tagatgttga taaaccaagt attagttgtc ttttcttatc tgttaaattt
     9481 tgatgccatt ttttaatctg atcattttct gagaataaat ctaataaggt caccatttat
     9541 ccgttatacc tctgcattgt tttctcaaaa tttttctctt gtaaatagta ttttacagaa
     9601 tcgtcaactt tgtcaacaga ctgtaaaata ccgatataat catccctgtc aaacttactc
     9661 aaaacatgat gaacaactga cataccattt ttaggtcttc caattccaat cttaacacgg
     9721 ttaaagacct gagttcctat atgttgaata atagacttga taccattatg accacctgct
     9781 gagccttttg ctcttaaacg aattttccca acttccatgt caagatcatc gtaaatgata
     9841 agtaaatcgt caatatccaa accatagtaa gttaataaag catgaactgc ttttccactt
     9901 tcattcataa aggtcgttgg tttaaccaga taaatttttt ctccatttag gaaaaaggat
     9961 gctaggtcag cttgaaatat cttatcgtgt gtaaaagtga cattctgttt cttcgctagt
    10021 tgatcaatca acataaaacc aacattgtgt tttgtttcaa aatatttatc ccctggattt
    10081 cccaaaccta caagtaattt ggtcatttat ttttcctttc aaaagccaaa agggttggaa
    10141 tttttttcca acctaattga caccatttat taatttttag acattaaagc ggaattctat
    10201 gatgtcgcca tcttgaacga tatattcttt tccttcttca cgcaagcgtc cagcttcttt
    10261 tacggccttt tcagatccgt atttcactag atcttcatat gacatggtta ctgcacgaat
    10321 aaagcctttt tcaaagtctg agtggataat accagctgct tgaggagcct tcataccacg
    10381 tttgaaagtc caagcgcgaa cttctttttc accagctgtg aagtaagttc ccaatccaag
    10441 caagtggtaa gctgcacgcg tcaacttatc tacacctgat tctgtcaaac caatggcttc
    10501 aagaaactct tttttatctt catcatccaa ttcagaaatt tcttcctcag cacgcgcaga
    10561 aataacgact acttcagcat tttctgtcgc tgcaaattca cgaatttgtt tgacatagtc
    10621 gatagagtca ggttctgaaa ccacatcctc gtccacatta gctacataaa gaactggttt
    10681 agtcgtcaaa aggaaaagac ctttgacaac cttttgttcc tcatctgtaa attcaatggt
    10741 acgagctgat ttcccgtctt ctaggactgg tttaatcttt tgaagaacat tgaattctgc
    10801 tactgattct ttatcttttt gcgtacgtgc catcttttct acacgcgcat atcgtttgtt
    10861 cactgattct aagtcagcaa gaattaattc cagattaatt gtatcaatat ctgcaagtgg
    10921 atctacaaag gcgtcttcac gtccttgctc gcgcatcaca ttttcatcat caaaagcacg
    10981 aactacgtga acaatcgcat ctacttcacg aatattggcc aagaatttat tccctagccc
    11041 ttctcctttt gaagctcctt ttacaatccc tgcaatatcc gtaaattcaa atgttgtggg
    11101 aactgtcttt ttaggagtta tcatttcagt tagtttttgt aggcgttcat ctggaacttc
    11161 caccattcca acatttggat caatcgtcgc aaatgggtag tttgctgcct ctgctcctgc
    11221 ttttgtaatt gcattaaata gtgttgattt accaacgttt ggcaaaccaa cgatacctgc
    11281 tgtcaaagcc atatttctca ttctccgttt tcatttcaat ccctaatatt ataacacaaa
    11341 aagggataaa gtgctaaccc tctaactaag ggttctcagt caataatttt attcattttt
    11401 cgctcaaaat catatcgccc catcatgaca acatgctcac aattactgca ttttattttg
    11461 atatctgctc ctacacgtgt aatttcccaa cgattagcct ttttaccagt cgacttgatt
    11521 gtacaagcgt gtgatttttt catctcaaca aaatttccaa cttgatacat actactctcc
    11581 ttttcttttt cgattatatc ataaaagagg cgagccaggc tcaacctctt tcacttaatt
    11641 tgtacgaact ggtgtaatga gctgcatgaa gtcttcgtca gtatctgctg gcacaagagt
    11701 aaatggacga acagctgaga taaagctaat ggtcaccttt tcgctattta aagctttaag
    11761 agaatcaatc aagtaagttg ggttgaaact aatggtcaaa tcttcaccag taacctgatc
    11821 agtatcgatt tcttcgttta ctttaccaac ttctggagag tgaacatggg cgctaacaac
    11881 cccatcctta atttcaagtt tcacagtacc attttgagtc gcacttgata aaagacgggc
    11941 acgctccatt gactggcgta agtttaccac attaaaagta atagtagtgt taaagtctgt
    12001 tggaatcaag cgatctgtat caggatagtt tccttctagg agacgagtat agaagctaat
    12061 attttcgctt ctaaagagga tttggttatt ggcaaagaaa atctctacag tttcgatatc
    12121 atctgtaaat accgctgaaa attcgcgtag agaacggcta ggaattacga catcaaaatc
    12181 atcactattt ttttcaagag tcaatttttt ctggcttagg cgatgagagt ctgttgcaac
    12241 tgtttttaac tctttgtgtt gactcaatac gaagtggaca cctgttaaaa tcggacgact
    12301 ctcttgtgta cttgcagcaa aggctgtttc attaataatt ttcttgagta attttgtttc
    12361 aagtattaaa ggagtgcttg ctgaaatttc ttggattcgt ggatattgtt cgctatcttt
    12421 tccttttagg gtaatttctg atttgccact ggttaaaaca atttgatttt gttcaatttc
    12481 tttaaaatca agagttacat caggtaaact agatactaca ttgataaaga aagaagcttc
    12541 aagaaggatc gaacctaaag aagtaattaa caaaccagca tcttcatttt tttgagaaat
    12601 aaaattttca attgaaattt gaccatttga accaattaaa gtaatacctt cattggtcac
    12661 gtcaattttt actgttgata aaataggaat ggcattttta gaactaatag ctctcttagt
    12721 agtatttaat gcttgtagaa ataaattttt attaattgaa aaatgaatca tggattctcc
    12781 tttatttatt tttagtatta gaaagataat agtaataata gagtctgtga aatctgtgga
    12841 aaacagcctt taaacaagtc atatcaagtt ttttagcttg tttaaaaaat gtggataaaa
    12901 aagataaaaa actaaaagtt atccacaaat tatttgattt tctttttgat tgattcaatt
    12961 tctaaacgta aattatcgtc ttgatcaatc aaagatttta ttttggcatg ggcatgaatg
    13021 actgtggtat gatcttttcc cccaaattcc ttcccaattt ttggaagact attatctgtt
    13081 agttctctag ataaatacat ggctacttga cgggccaaaa caatattttg aaggcgtcta
    13141 cttcccttca tttctttgat actaacacca taaaagttac caacttcagt ttggatttta
    13201 tcaattggga tgacgagcat ttggctaaca tcttgtttgc gggctctaat ggcttctgca
    13261 gcaatatcaa tagtgatatc cttgattttt tttactctgg caattaaagt gatgtcgttg
    13321 atggctccct caagatctcg aacatttgaa tcaaattgcc cagctaggta ttctagagta
    13381 tcactttgga aattgtagcc taaatgttcc gttttacttt gtaaaatggc aatacgtgtt
    13441 tcaaagtcag ggggtgtgat agtttgtgtc aatccccaac taaaacgcgt gacaagcctc
    13501 tcctcgagcc cttctagatg ttttggacta cgatcactcg ttaggacaat ctgtttttgc
    13561 ttgtcatgaa gggcgttaaa ggtattgaaa aattcttcct gagttgcgac tttttttccg
    13621 ctgagtgact ggatatcatc gattaacaaa agatcaagac tacgataggt ctttttaaac
    13681 ttttccattt ccccaagtct taggtgatca agaaagtcat taataaagct ttcggcaggg
    13741 atatatttaa cacgcgcatt aggaatattt tttagaattt catttccaat agcgtttaat
    13801 aagtgagtct taccaaggcc tggtcctcca tagataaaaa gagggttata ggtcagagcc
    13861 aaatcttcag agacagctaa agcggctgac acagcccaaa catttccatc cccttgaata
    13921 aagttatcaa aggtatactt ttcttttaat cccgtatctg aataaggaat agatactaac
    13981 tttggactat agttataaag agttaaattt gtagcttctt caacttgtga gctagtcgta
    14041 tcttgaggtt tggtgaaaat atagtgggga gttatttcag cgtcataaat ttcaaaacca
    14101 gctactacaa taatatcttt tagttgtttt tcccagacca tttccatttc agagcgaggt
    14161 agaaatatag tggcaacatt ttcctctacc ttgatgagtt cagcttgaat agcatagaaa
    14221 tcatacatgg atcgagtcag tctttcttgt gcaaattcta atatacgatt ccaaaattgt
    14281 ttttctttca atcctttctc ctcctttact atttaaaagt ttaatactag agatatttta
    14341 ccatagatag caagaatttt ccacaagctg tgaaaaataa tccacaatgt taccaaactt
    14401 tatccacagg ttggggataa aagaagaaat tattgattta ttaagctttt tattgaaaaa
    14461 catagtggat aaccttgtga gataaaaaaa taaaagaaca gccttatttc aggctgttga
    14521 taattctact atattcttct tgatttgaaa aagaaataat gatttttcca ctgtcttttt
    14581 tagatagttt aatttctaca tctaatccga gtagttttct taactgtttt tcttcatttt
    14641 gtatgaaatg attagttttt tgctgtttct tttgtttttt ctctgtcaga agagcttcta
    14701 atttccttac agaaatatct tcttctataa tccgttgaaa gaaatagtct tgttgttcct
    14761 tatttaaccc aactagggaa cgcgcatggg cttgtgatag tttgccattt tctacttctg
    14821 aaagaatctg ttctggcaag gaaagtaaac gaatggagtt gctgatatat ggacgagact
    14881 tgcccatctt atctgcaatt tcagcatggg tgaatccttt ctctacgaga gattcatagg
    14941 cgcgtgcttc ttctattggg tttaaatttt ctctctgtaa attttcaata atggactgga
    15001 ccatcatctc ttggtctgaa atctgtttaa caacagctgg gatagaccgt agaccagcta
    15061 aaagtgaagc ccgatagcgt ctctctcctg caaggatttc ataaccaata acaggagatt
    15121 gacgaacaat aatcggttga atgaccccat tttctttgat agactgtgct agttcatcta
    15181 gtttttctct atcaaattct tttcggggtt gatagggatt tttttgtata tctgtgatag
    15241 aaatcatttc aaatttttcc atgattctac actaacacat cttttctctt atgtaaagct
    15301 ttctttacat agatgtcaat taagattcta aatcacctga actcttgtta agtttgatag
    15361 aggtagtttc ttctttcccg ttacgatagt aggttatctt aatggtgtct ccgatagaat
    15421 ggttgtaaag agcactttgt aagtctgttg atgaagcaat ctctttgtca tctacttttg
    15481 taattacatc gtatttttca aggtgaccat tggcaggcat attactttgt accgaacgaa
    15541 caactacacc agatgtaaca ttacttggaa tattgagtct tctgatgtcg cttgtactca
    15601 cattagataa attaaccatc tggattccca aagctggacg cgtcactttt ccgttttttt
    15661 ctaactgttc aataatattg atagcatcat ttgcaggaat tgcgaaacca agaccttcta
    15721 cagatgttcc tccatttgta gcaattttac ttgaggtaat tccgataacc tgcccttgaa
    15781 tattgatcag tgggccgcca gagttacctg ggttaatagc agtatcagtt tggatggctt
    15841 ttgtagaaat agcttgtcca tcttccgatt ttaaggatac atttctattg agactggata
    15901 cgataccttg agtgacagta tttgcatatt cagaacctaa cgggctaccg atggcaatag
    15961 cagtttctcc tacagttaac ttactagaat caccaaactc agctactgtt gtcacttttt
    16021 ctgaagagat ttttacgaca gcaatatcag agaaagtgtc agctccgaca atttctccag
    16081 gtactttagt cccatctgac aatcgaatat ctactttgct ggcgccattt ataacgtgat
    16141 tgttggtgac gatgtaagct tctttatcat tctttttata aataactcca gatccttcac
    16201 tagagattcg ctgagaatct gtgtcagtat catcattgcc aaatacgcta ttttgtctgt
    16261 ttgccgaata agtaataaca gaaacaacag catcttttac tttgttaaca gcctgtgttg
    16321 ttgaattttc gttcttatag gcagtttgtg taatagtact attgttgtta gagttgttta
    16381 cactactttt ttgagttagt tgagttattg aaaaactacc caaggctcca ctaaaaaagc
    16441 taatgacgat aacgactaat aattgaaacc attttttgta aaatgttttt agatgtttca
    16501 tatttgcctc catatgtttg aattactgaa agtataaact gactagctta attataactt
    16561 aaacacaaaa gttttacaca aactgtggat aactcttttg aaactgtgat tttcttaatt
    16621 gaaatctatt ttttattttg tgaataagat gtgaaaaaat agagaatatg ttagaataga
    16681 gtcatgaaaa ttaaagttgt aacagttggg aaactgaaag aaaagtattt aaaagatggt
    16741 atcgcagagt attcaaaacg aatttctaga tttgctaagt ttgaaatgat tgagttatca
    16801 gatgaaaaaa caccagataa ggccagtgaa tcagaaaatc aaaagatttt agaaatagaa
    16861 ggtcagagaa ttttatcaaa aattgctgac cgtgatttcg ttattgtgtt agccattgaa
    16921 gggaaaactt tcttctcaga agaatttagt aagcagttag aagaaacttc tataaaagga
    16981 ttttctactc ttacttttat tattggggga agtttaggat tgtcatcatc tgtaaaaaat
    17041 agagccaatc tttctgtcag ttttggtcgc ctaaccttac cccatcagtt aatgagacta
    17101 gttcttgttg aacaaatcta tcgcgctttt acgattcagc agggattccc ctaccataaa
    17161 tagaaaattg acttttaatt gaatttttgg tagaataatt gtattaggtc tcatagctca
    17221 gctggataga gcattcgcct tctaagcgaa cggtcgcagg ttcgaatcct gctgggatca
    17281 atataatagc aaagctggga attttcccgg cttttttctt aaaaaagtac actttgggag
    17341 aaaaaaatga cagttgagag aattttatct aaaacgaaat tccattttgt ataatggttt
    17401 ttgtaagtta gcttacaaga aaaaacattt taggagattt tattatgaaa aacacagtta
    17461 aattggaaca gtttgtagct ttgaaggaaa aagacttaca aaagattaaa ggtggggaga
    17521 tgaggttgtc aaaattcttc cgtgatttta ttttacaaag aaaaaagtaa tgaaataagg
    17581 ggaaagagta atggatttat ttggatttgg gacggttatt gttcattttt taattattag
    17641 tcacagttac cattttattt gtaaaggtca aataaataga aaagaattat tcgtttttgg
    17701 tgcttataca ttactaacag aaatagtatt tgattttccc ttatatattc tatatttaga
    17761 tgggttaggg attgaaagat ttttatttcc tttgggatta tattcctatt ttcgatggat
    17821 gaaacagtat gagagggata gaggactatt cctaagttta ctactatctc ttttatatga
    17881 gagcactcat aactttctgt ccgtaacttt ctcctctata acaggagata attttgtttt
    17941 acaatatcat ttcccattct ttttcgttgt gacggtgtta acctattttg ttacattaaa
    18001 aatcatttac tatttccatt tggaactagc ctattttgac gaggactacc tttatccttt
    18061 cttgaaaaaa gtattttttg ctttactatt gctacatatt gtatctttcg tttcagatat
    18121 ggtaagtacg attaaacatt tgaatagttt tggaagtatt ttgtcatcta ttgtctttat
    18181 ctctctcctt ttgaccttct ttgcaatgaa ttctcataaa gttcaaatgg agaaagagat
    18241 tgctttgaag cagaagaaat ttgaacagaa acatttacag aattacacag atgaaattgt
    18301 tggtctgtat aatgaaatcc gtggttttcg acatgattat gctggaatgc ttgtcagcat
    18361 gcagatggca attgacagtg gtaatttaca ggaaattgac agaatttaca atgaagtttt
    18421 agtcaaagca aatcataaat tgcgttcaga taagtacact tactttgatt tgaacaacat
    18481 agaagactca gctttacgaa gtttggttgc tcagtcaatt gtctatgctc gaaataatgg
    18541 tgtagagttt acactggaag taaaagatac gattaccaag cttccaattg aactattgga
    18601 tttggttcgt atcatgagcg ttttattgaa taatgctgtc gaaggatcgg ctgatagcta
    18661 taaaaagcag atggaagtag cagttattaa gatggaaact gaaacagtta ttgtgattca
    18721 gaattcatgt aaaatgacga tgactccttc aggagatcta tttgccttag gattctccac
    18781 taagggaaga aatcgcggag tcggattaaa taatgtgaaa gaactactag ataagtacaa
    18841 caatattatt ttagaaacag agatggaagg cagtacattt agacaaatca ttagatttaa
    18901 gagggaattt gaatgaaagt tttaatttta gaagatgtta ttgaacatca agtgagacta
    18961 gagagaatat tggatgaaat ttcgaaagaa tcgaatattc caatatcata caagacaacg
    19021 ggaaaagtcc gtgaatttga agaatacatt gaaaatgatg aagtaaatca gctttatttc
    19081 ctagatatcg atattcatgg aattgagaaa aagggatttg aagtggctca gctcattcgt
    19141 cattacaatc cttacgctat tatcgtcttt atcactagtc gatcagagtt tgcgactcta
    19201 acctataaat accaggtatc agccctagat tttgttgata aggatatcaa tgatgagatg
    19261 tttaagaaga gaattgagca aaatatcttc tacacgaaga gtatgttact tgaaaatgaa
    19321 gatgttgtag attatttcga ctacaattac aagggaaatg atttaaaaat tccttaccat
    19381 gatattttgt atattgaaac aacaggggtc tctcataaat tgcgcattat tggtaagaat
    19441 tttgcaaaag agttttatgg taccatgaca gatattcagg aaaaggacaa acatactcag
    19501 cgattttatt ctcctcacaa gtcatttttg gtaaatatag gcaatatcag agaaattgat
    19561 cgaaaaaact tagaaattgt tttctatgaa gaccatcgtt gtcctatttc aagattaaaa
    19621 attagaaaat taaaagatat tttagagaaa aaatctcaaa agtgattgac aattagcaag
    19681 aaattgatat aatggttata tctgctacag atagaaggtc cgttggtcaa ggggttaaga
    19741 caccgccttt tcacggcggt aacacgggtt cgaatcccgt acggactatt ttatccgcca
    19801 tagctcagtt ggtagtagcg catgactgtt aatcatgatg tcgtaggttc gagtcctact
    19861 ggcggagtat agataaaagg gaacacagct gtgttcctct ttttgtatca atttgtatca
    19921 ccaagcattt tcataaggaa gtctgttatt tcttgagaac tttctttttt tccatgtgca
    19981 atccaagttt ggcagacacc aaaaagtgca tgagttagat agatgctact atattctaat
    20041 tcggtggtat ttagattcag ttgcataaat cgcttttgta aatctgtact aagcatgata
    20101 tgaagtttat ttcgtaagaa attttggatt tctttagtcc cattttcaga aagaagggca
    20161 gccagaagtg gttctgactc tagatattca aaaacttcta aaatagcgtc tcttttgtga
    20221 tgagcatgtt tttgaaaaat atattcaaat gtatggaata gcttgctttg atagtgctca
    20281 atcatatcat acttatcctt atagtgagta tagaagctgg aacgactaat tccggctttt
    20341 tctactaatt tgacagtaga aattttatca aatggctgtt ccatcagtaa ttgtaccata
    20401 gcattttcaa tagttcgctt tgtttttaag cgtttgttac tttcttgcat atttcctcct
    20461 tgtaaacaaa ttagactata tgtttaaaaa tagatttttt atcttgtaat ttagattttt
    20521 taatgtataa tctattatat caaaatttta gacaatatgt ttaaaaaagg agaaactaag
    20581 tttaaagaat ggaaagcaat ttaaaaaaaa ccaaccttta ttattgtcat gatcgggatt
    20641 tctcttattc cagatctgta caatatcata tttttgtcat caatgtggga tccatatggg
    20701 caattgtctg acttacctgt ggcagttgta aataatgata aagaggcttc ctataatggt
    20761 aatactatgg caataggaaa agacatggtg tccaatttaa aagaaaataa aaccttggat
    20821 tttcattttg tagatgaaga ggaaggaaag aagggattgg aagatggcga ttactatatg
    20881 gtagtgactt taccaagtga tttatctgaa aaaacaacta cattatccaa tattcaatcg
    20941 acagcagctt atcaatcatt gacaagtgag caacaaactg agataagtga ttctgtatct
    21001 caaaattcaa ctgatagtat tcaatcggct cagtcaattg tagctttagt acaagattta
    21061 cagggaagtt tagaaaactt acaaaatcaa tcttctaatc tttcgacttt aaaaaatcaa
    21121 tctaatcaag tatcacctat tacttctact tctttgatag gattgtcaag tggattaaca
    21181 gagatacaag gagatgttac tagcaaatta gttcctgcca gtcagtcgat tgcatcaggt
    21241 gtaaacgcat atactacagg tgttgataaa gtttctcagg gcgcaagtca actaagtgaa
    21301 aaaaatgcca ccttgacagg tagtttggat aaactagttt caggctcaaa caccttgaca
    21361 caaaaatctt ctagattgac agcaggagtt ggttaattac aatcaggatc tgggcaatta
    21421 gcagacaaat ccagtcagtt actttcaggt gcttctccat tagagaatag agctaataaa
    21481 ttggcagatg gatctgggaa actagcagaa ggtggaacaa agttaacttc tggattggaa
    21541 gatttacaga caggacttgc ttctttagga caaggactag gtaatgctag tgatcaactc
    21601 aaatcagtat caacagaatc taaaaatgca gagattttgt caaatccact caatctttca
    21661 aaaacagaca atgatcaagt tcctgtaaat ggaatcgcaa tagctcctta tatgatatca
    21721 gttgctcttt ttgttgcagc aatatcaaca aatatgatat ttgcgaaatt gccttcagga
    21781 cgtcatccag agagccgttg ggcttggttg aaatctcgag ctgaaataaa tggtattata
    21841 gctgttttgg caggaatttt ggtatatgga ggagttcagc ttattggttt aactgctaat
    21901 catgagatga gaatatttat tctcatcatc ctaacaagtt tagtattcat gtctatggtg
    21961 accactttaa caacgtggaa tagccgtata ggagcttttt tcttacttat tttgctttta
    22021 ctacagttag catcaagtgc aggtacttat ccacttgctt tgacaaatga tttctttaga
    22081 tctattaatc cctggttacc aatgagctat tcagtttcgg gattacgaca aacaatctct
    22141 atcaacaagt cattttccta gctgtcatac tagctctatt tactggttta ggtatgctag
    22201 cctatcaaca taagaaaatg gaagaagatt aaaaaaatcg accgattaat gaactgcacc
    22261 ccaaaagtta gacagaaaaa atctaacttt tgaggtgttt tattatgaaa ttaa
//
LOCUS       DAVBBO010000033        22104 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ST1
            SAMEA2066453-rid20184263.denovo.033, whole genome shotgun sequence.
ACCESSION   DAVBBO010000033 DAVBBO010000000
VERSION     DAVBBO010000033.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2066453
            Sequence Read Archive: ERR351777
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 22104)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 22104)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980402.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980402.1
            Genome Coverage       :: 176x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:17:33
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,141
            CDSs (total)                      :: 2,104
            Genes (coding)                    :: 1,953
            CDSs (with protein)               :: 1,953
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 16S)
            partial rRNAs                     :: 1 (23S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 151
            CDSs (without protein)            :: 151
            Pseudo Genes (ambiguous residues) :: 0 of 151
            Pseudo Genes (frameshifted)       :: 73 of 151
            Pseudo Genes (incomplete)         :: 76 of 151
            Pseudo Genes (internal stop)      :: 40 of 151
            Pseudo Genes (multiple problems)  :: 32 of 151
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..22104
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2066453-rid20184263.denovo.033"
                     /strain="ST1"
                     /db_xref="taxon:1313"
     gene            complement(<1..389)
                     /locus_tag="VQU30_001285"
     CDS             complement(<1..389)
                     /locus_tag="VQU30_001285"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000846948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="immunity protein"
                     /protein_id="HET2447394.1"
                     /translation="MKTFFAKKRNIFLARLFLGQLPLLVSTYLFLSRQFLNFSVVFQF
                     LLVVINLASILVTVYLTREMRIREFEDDDLVSPRTNQLMFIGLTGFMSIICLYRGITA
                     GESYQQIIAYIGAVLCLIIMLLLMWGL"
     gene            complement(386..550)
                     /locus_tag="VQU30_001286"
     CDS             complement(386..550)
                     /locus_tag="VQU30_001286"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000727119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2447395.1"
                     /translation="MKKKILIIFVLYLIMSIFLYPLRESAWYQLFYTIAYVIAVMIYF
                     AINKKKGEKK"
     gene            complement(849..968)
                     /locus_tag="VQU30_001287"
     CDS             complement(849..968)
                     /locus_tag="VQU30_001287"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397130.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin"
                     /protein_id="HET2447396.1"
                     /translation="MDFKSFIIGLVVGIFGPYMYNLIRKIFSKFPKKDTDSTP"
     gene            complement(971..1201)
                     /gene="blpU"
                     /locus_tag="VQU30_001288"
     CDS             complement(971..1201)
                     /gene="blpU"
                     /locus_tag="VQU30_001288"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001093487.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin-like peptide BlpU"
                     /protein_id="HET2447397.1"
                     /translation="MDTKMMSQFSVMDTEMLACVEGGGCNWGDFAKAGVGGAAARGLQ
                     LGIKTGTWQGAATGAAGGAILGGVAYAATCWW"
     gene            complement(1270..1539)
                     /gene="blpJ"
                     /locus_tag="VQU30_001289"
     CDS             complement(1270..1539)
                     /gene="blpJ"
                     /locus_tag="VQU30_001289"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001093248.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin-like peptide BlpJ"
                     /protein_id="HET2447398.1"
                     /translation="MNTKMLSQLEVMDTEMLAKVEGGYSSTDCQNALITGVTTGIITG
                     GTGAGLATLGVAGLAGAFVGAHIGAIGGGLTCLGGMVGDKLGLSW"
     gene            complement(2006..2203)
                     /gene="blpI"
                     /locus_tag="VQU30_001290"
     CDS             complement(2006..2203)
                     /gene="blpI"
                     /locus_tag="VQU30_001290"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001093259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin-like peptide BlpI"
                     /protein_id="HET2447399.1"
                     /translation="MNTKMMEQFSVMDNEELEIVSGGRGNLGSAIGGCIGAVLLAAAT
                     GPITGGAATLICVGSGIMSSL"
     gene            2485..3072
                     /locus_tag="VQU30_001291"
     CDS             2485..3072
                     /locus_tag="VQU30_001291"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001855030.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase C39"
                     /protein_id="HET2447400.1"
                     /translation="MTSYKRTFVPQIDARDCGVAALASIAKFYGSDFSLAHLRELAKT
                     NKEGTTALGIVKAADEMGFETRPVQADKTLFDMSDVPYPFIVHVNKEGKLQHYYVVYQ
                     TKKDYLIIGDPDPSVKITKMSKERFFYEWTGVAIFLATKPSYQPHKDKKNGLLSKLPS
                     SDFQTKISHCLHCSLKLIGHYYQYRWFLLSPRNLG"
     gene            3065..4654
                     /locus_tag="VQU30_001292"
                     /pseudo
     CDS             3065..4654
                     /locus_tag="VQU30_001292"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864064.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="peptide cleavage/export ABC transporter"
     gene            4665..6026
                     /locus_tag="VQU30_001293"
     CDS             4665..6026
                     /locus_tag="VQU30_001293"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001069090.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin secretion accessory protein"
                     /protein_id="HET2447401.1"
                     /translation="MNPNLFRSVEFYQRRYHNYATVLIIPLSLLFTFILIFSLVATKE
                     ITVTSQGEIAPTSVIASIQSTSDNPILANHLVANQVVEKGDLLIKYSETMDESQKTAL
                     ETQLQRLEKQKEGLGILKQSLEKATDLFSGEDEFGYHNTFMNFTKQSHDIELGITKTN
                     TEVSNQANLANSSSSAIEQEITKVQQQIGEYQELRDAIINNRARLPTGNPHQSILNRY
                     LIASQGQTQGTAEEPFLSQINQSIASLESSIASLKIQQAGIGSVATYDNSLATKIEVL
                     RTQFLQTASQQQLTVENQLTELKVQLDQATQRLENNTLTAPSKGIVHLNSEFEGKNRI
                     PTGTEIAQIFPVITDTREVLITYYVSSDYLLLLDKGQTVRLKLEKIGNHGTTIIGQLQ
                     SIDQTPTRTEQGNLFKLTALAKLSNEDSKLIQYGLQGRVTSVTTKKTYFDYFKDKILT
                     HSD"
     gene            6083..6238
                     /gene="blpC"
                     /locus_tag="VQU30_001294"
     CDS             6083..6238
                     /gene="blpC"
                     /locus_tag="VQU30_001294"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000358812.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="quorum-sensing system pheromone BlpC"
                     /protein_id="HET2447402.1"
                     /translation="MDKKQNLTSFQELTTTELNQIIGGGWWEDFLYRFNIIEQKNTKG
                     FHQPIQL"
     gene            complement(6282..7622)
                     /locus_tag="VQU30_001295"
     CDS             complement(6282..7622)
                     /locus_tag="VQU30_001295"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001099894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HET2447403.1"
                     /translation="MNVAWILLYTLVTHGLKIVIFFKVDGISLTFERIFKAFLFKILL
                     AVVFGMLGYMVGNTYLSYFMEPLYGIGLSFLLLRELPKKLLLFYGLFPMILVNLFYRG
                     VSYFVLPFLGQGQVYDDYSFIWLCIIIFNFFISLAFLKWLDYDFTSLRKGILDKDFQK
                     SLTQINWIMGAYYLVIQNLSYFEYEQGIQSTTVRHLILVFYLLFFMGIIKKLDTYLKD
                     KLHERLNQEQDLRYREMERYSRHIEELYKEVRSFRHDYTNLLTSLRLGIEEEDMEQIK
                     EIYDSVLKDSSEKLQDNKYDLGRLVNIRDKALKSLLAGKFLKARDKNIVFNVEVPEEI
                     QVEGMSLLDFLTVVSILCDNAIEASVEACQPHVSIAFLKNGAQETFIIENSIKEEGID
                     ISEIFSFGASSKGEERGVGLYTVMKIVESHPNTSLNTTCQDHVFRQVLTVIHIE"
     gene            complement(7636..8373)
                     /locus_tag="VQU30_001296"
     CDS             complement(7636..8373)
                     /locus_tag="VQU30_001296"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001219153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HET2447404.1"
                     /translation="MRIFVLEDDFSQQTRIETTIEKLLKEHHITPSSFEVFGKPDQLL
                     AEVHEKGAHQLFFLDIEIRNEEMKGLEVARKIRDRDPYALIVFVTTHSEFMPLSFRYQ
                     VSALDYIDKALSAEEFESRIETALLYANGQDSKSLAEDCFYFKSKFAQFQYPFKEVYY
                     LETSTRPHRVILYTKTDRLEFTASLEEVLKQEPRLLQCHRSFLINPANVVHLDKKEKL
                     LFFPNGGSCLIARYKVREVSEAINNLH"
     gene            complement(8378..8716)
                     /locus_tag="VQU30_001297"
     CDS             complement(8378..8716)
                     /locus_tag="VQU30_001297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000682119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HET2447405.1"
                     /translation="MKHMIIQTQKTVYKVNVDDIYYIQTHPTKAHTVQIVTEEASFNM
                     LQNLSNLENQYGETLMRCHRNCLVNLDKLKSIDFQERILFLGEEGQYAVKYARRRYRE
                     IRQKWLKEGE"
     gene            8993..9322
                     /locus_tag="VQU30_001298"
     CDS             8993..9322
                     /locus_tag="VQU30_001298"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864062.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helicase BlpT"
                     /protein_id="HET2447406.1"
                     /translation="MTDTDPIKRAHTLITDLNKAYQACKQASADDVRFQEQLNSILGF
                     LAKAETVDNRFLIELEKFYQTSSLLMGLSALDPDAPTRAAWRAYDRFHFDQVKTKLIL
                     NENQRAN"
     gene            complement(9490..10539)
                     /locus_tag="VQU30_001299"
     CDS             complement(9490..10539)
                     /locus_tag="VQU30_001299"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399209.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HET2447407.1"
                     /translation="MKDLFLKRKQAFRKECLCYLRYVLNDHFVLFLLVLLGFLAYQYS
                     QLLQHFPENHWPILLFVGITSVLLLLWGGIATYMEAPDKLFLLVGEEAIKLHLKRQTG
                     ISLVFWLFVQTLFLLLFAPLFLAMGYGLPVFLLYVLLLGVGKYFHFRQKASKFFTETG
                     LDWDYVISQESKRKQVLLRFFALFTQVKGISNSVKRRAYLDFILKAVQKVPGKIWQNL
                     YLRSYLRNGDLFALSLRLLLLSVLAQVFIEQAWIATAVVVLFNYLLLFQLLALYHAFD
                     YQYLTQLFPLDKGQKEKGLQEVVRGLTSFVLLVELVVGLITFQEKLALLALLGAGLVL
                     LVLYLPYQVKRQMQD"
     gene            complement(10536..11267)
                     /locus_tag="VQU30_001300"
     CDS             complement(10536..11267)
                     /locus_tag="VQU30_001300"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000889926.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET2447408.1"
                     /translation="MLEIKNLTGGYVHVPVLKDVSFTVESGQLVGLIGLNGAGKSTTI
                     NEIIGLLAPYSGSININGLTLQGDATSYRKQIGYIPETPSLYEELTLREHIETVAMAY
                     GIEQKVAFERVEPLLKMFRLEQKLDWFPVHFSKGMKQKVMIICAFVVDPSLFIVDEPF
                     LGLDPLAISDLIQLLEVEKQKGKSILMSTHVLDSAEKMCDAFVILHKGEVRAKGNLLQ
                     LREAFDMPEASLNDIYLALTKEEDL"
     gene            11335..11745
                     /locus_tag="VQU30_001301"
     CDS             11335..11745
                     /locus_tag="VQU30_001301"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006150090.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HIT family protein"
                     /protein_id="HET2447409.1"
                     /translation="MSDCIFCKIIAGEIPASKVYEDEQVLAFLDISQVTLGHTLVVPK
                     EHYRNLLEMNATSASQLFAQVPKVAQKVMKVTKAAGMNIISNCEEVAGQTVFHTHVHL
                     VPRYSADDDLKIDFIAHEPDFDKLAQVAETIKNA"
     gene            11755..12042
                     /locus_tag="VQU30_001302"
     CDS             11755..12042
                     /locus_tag="VQU30_001302"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000777751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2447410.1"
                     /translation="MKLSNLLLFAGAAAGSYLVTKNRQTITDEVLNTTDRVQAIKDDV
                     DIIQNSLQIIDQQKELIKEYQEDLTYKFKVLEKDIQTRLAVIKEMQGTEDK"
     gene            12204..12443
                     /locus_tag="VQU30_001303"
     CDS             12204..12443
                     /locus_tag="VQU30_001303"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2447411.1"
                     /translation="MHHNLGNSYSIKIKKQTRKLGTDCSKHRFKVVDRTDEVSSKHCF
                     EVVDRTDEVSNHTHDKPTLTWFEEIFEEYHSPFHN"
     gene            complement(12793..13929)
                     /gene="dnaJ"
                     /locus_tag="VQU30_001304"
     CDS             complement(12793..13929)
                     /gene="dnaJ"
                     /locus_tag="VQU30_001304"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001066288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molecular chaperone DnaJ"
                     /protein_id="HET2447412.1"
                     /translation="MNNTEFYDRLGVSKNASADEIKKAYRKLSKKYHPDINKEPGAED
                     KYKEVQEAYETLSDDQKRAAYDQYGAAGANGGFGGAGGFGGFNGAGGFGGFEDIFSSF
                     FGGGGSSRNPNAPRQGDDLQYRVNLTFEEAIFGTEKEVKYHREAGCRTCNGSGAKPGT
                     SPVTCGRCHGAGVINVDTQTPLGMMRRQVTCDVCHGRGKEIKYPCTTCHGTGHEKQAH
                     SVHVKIPAGVETGQQIRLAGQGEAGFNGGPYGDLYVVVSVEASDKFEREGTTIFYNLN
                     LNFVQAALGDTVDIPTVHGDVELVIPEGTQTGKKFRLRSKGAPSLRGGAVGDQYVTVN
                     VVTPTGLNDRQKVALKEFAAAGDLKVNPKKKGFFDHIKDAFDGE"
     gene            complement(14134..14487)
                     /locus_tag="VQU30_001305"
     CDS             complement(14134..14487)
                     /locus_tag="VQU30_001305"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000115730.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2447413.1"
                     /translation="MSVNKNNLSDIADYHEKIKFFEELFNLDYNPTEMLVTVERNGNV
                     IYKEFTEVAVGKSKYDHTSVFKDVMIYFSDHICQELHLYKTQDPHYNKFEFDLAKRSL
                     KITTRDNTTIFISNE"
     gene            complement(14500..16323)
                     /gene="dnaK"
                     /locus_tag="VQU30_001306"
     CDS             complement(14500..16323)
                     /gene="dnaK"
                     /locus_tag="VQU30_001306"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002946936.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molecular chaperone DnaK"
                     /protein_id="HET2447414.1"
                     /translation="MSKIIGIDLGTTNSAVAVLEGTESKIIANPEGNRTTPSVVSFKN
                     GEIIVGDAAKRQAVTNPDTVISIKSKMGTSEKVSANGKEYTPQEISAMILQYLKGYAE
                     DYLGEKVTKAVITVPAYFNDAQRQATKDAGKIAGLEVERIVNEPTAAALAYGLDKTDK
                     EEKILVFDLGGGTFDVSILELGDGVFDVLSTAGDNKLGGDDFDQKIIDHLVAEFKKEN
                     GIDLSTDKMAMQRLKDAAEKAKKDLSGVTSTQISLPFITAGEAGPLHLEMTLTRAKFD
                     DLTRDLVERTKVPVRQALSDAGLSLSEIDEVILVGGSTRIPAVVEAVKAETGKEPNKS
                     VNPDEVVAMGAAIQGGVITGDVKDVVLLDVTPLSLGIETMGGVFTKLIDRNTTIPTSK
                     SQVFSTAADNQPAVDIHVLQGERPMAADNKTLGRFQLTDIPAAPRGIPQIEVTFDIDK
                     NGIVSVKAKDLGTQKEQTIVIQSNSGLTDEEIDRMMKDAEANAEADKKRKEEVDLRNE
                     VDQAIFATEKTIKETEGKGFDAERDAAQAALDDLKKAQEDNNLDDMKAKLEALNEKAQ
                     GLAVKLYEQAAAAQQAQEGAEGAQATGNAGDDVVDGEFTEK"
     gene            complement(16803..17327)
                     /gene="grpE"
                     /locus_tag="VQU30_001307"
     CDS             complement(16803..17327)
                     /gene="grpE"
                     /locus_tag="VQU30_001307"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000046028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotide exchange factor GrpE"
                     /protein_id="HET2447415.1"
                     /translation="MAQDIKNEEVEEVQEEEVVETAEETTPEKSELDLANERADEFEN
                     KYLRAHAEMQNIQRRANEERQNLQRYRSQDLAKAILPSLDNLERALAVEGLTDDVKKG
                     LGMVQESLIHALKEEGIEEIAADGEFDHNYHMAIQTLPADDEHPVDTIAQVFQKGYKL
                     HDRILRPAMVVVYN"
     gene            complement(17354..18388)
                     /gene="hrcA"
                     /locus_tag="VQU30_001308"
     CDS             complement(17354..18388)
                     /gene="hrcA"
                     /locus_tag="VQU30_001308"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011999912.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heat-inducible transcriptional repressor HrcA"
                     /protein_id="HET2447416.1"
                     /translation="MVTERQQDILNLIIDIFTKTHEPVGSKALQESINSSSATIRNDM
                     AELEKQGLLEKAHTSSGRMPSVAGFQYYVKHSLDFHRLAENEVYEIVKAFDQEFFKLE
                     DILQEAANLLTGLSGCTVVALDVEPSRQRLTAFDIVVLGQHTALAVFTLDESRTVTSQ
                     FLIPRNFLQEDLLKLKSIIQERFLGHTVLDIHYKIRTEIPQIIQRYFTTTDNVIDLFE
                     HIFKEMFNENIVMAGKVNLLNFANLEAYQFFDQPQKVALEIREGLREDQMQNVRVADG
                     QESCLADLAVISSKFLIPYRGVGILAIIGPVNLDYQQLINQVNVVNRVLTMKLTDFYR
                     YLSSNHYEVH"
     gene            complement(18552..19061)
                     /locus_tag="VQU30_001309"
     CDS             complement(18552..19061)
                     /locus_tag="VQU30_001309"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001088691.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2812 domain-containing protein"
                     /protein_id="HET2447417.1"
                     /translation="MNSRVEFRIFTIVDLDKEEEYLHEMHLKGWRYRTSRFGLFYFDQ
                     CQPDDVIYRIYDSRFLKKYKHELQDFRDRGWELIGAGSCSILRKSSSDLLPEDQVYMS
                     KGLKWEVMRSRLRSCTTTFLGGLVVCTSLFREDLSMSFFLIFVLYAFLISYLIHGYFR
                     LKRKYRVDE"
     gene            19669..21606
                     /locus_tag="VQU30_001310"
                     /pseudo
     CDS             19669..21606
                     /locus_tag="VQU30_001310"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399214.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase family protein"
     gene            21604..22104
                     /locus_tag="VQU30_001311"
                     /pseudo
     CDS             21604..22104
                     /locus_tag="VQU30_001311"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001819352.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
BASE COUNT         6993 a         4580 c         3952 g         6579 t
ORIGIN      
        1 ttcaagcccc acatgagcag aagcatgatg attaagcaga gaacagcgcc aatataagcg
       61 attatttgtt ggtaggattc tcctgctgtg atacctctat acaaacaaat aatagacata
      121 aaacctgtca agccgatgaa cataagttga ttggttctag gactaaccaa atcatcatct
      181 tcaaactctc ttatcctcat ttccctagtg agataaacag taaccaaaat agaagccaag
      241 ttaataacta ctaaaagaaa ttggaaaact acggaaaaat ttaaaaactg acgagataga
      301 aatagataag tagaaacaag caagggcaac tgacctaaga acaatctcgc aaggaagatg
      361 ttccgttttt tagcaaaaaa agttttcatt tcttttctcc tttcttttta ttgatagcaa
      421 aatagatcat aactgcaatc acataggcta tggtataaaa tagctgatac caagcactct
      481 ccctaagcgg atatagaaag atggacatga ttagatacag aacgaaaata atcagtattt
      541 ttttcttcat aagatttcct cctaaatgtg cgatttatct tagttgagca agaacattta
      601 cactgctagt atagcactta ttttgacctt ggatcactca aatcataaat ggtcatcgaa
      661 acatcttgaa ttgttaaaaa atttaaaaag taagcattaa aaacatactt tcctctttat
      721 attgtattga taccaacttg tttgtagact tttcatcctg ctatcacata tcattttgac
      781 aggcgaaaca aaattaaaga aactcccctg taaattaagc tagcaaatac aggggagaaa
      841 tttatttttt agggggtact atctgtatcc tttttgggaa attttgaaaa tatttttcta
      901 attaaattat acatataagg accaaatata ccaactacta aaccaataat aaaactttta
      961 aaatccataa ttaccaccaa catgttgctg cataggctac acctccaagt atagctccac
     1021 ccgcagcacc agttgctgca ccttgccatg ttcctgtttt aatgcctagt tgaagacctc
     1081 ttgctgctgc tcctccaaca cctgctttgg caaaatctcc ccaattgcat ccgccacctt
     1141 caacgcaagc aagcatttca gtatccataa cagaaaattg tgacatcatt tttgtatcca
     1201 tgacaaatac tcctttttta aaaaactaaa ataaatcaga atagaatcct cataatttta
     1261 ctataagtct taccaactta gtcccaattt atcaccaacc atacctccta agcatgttaa
     1321 tccaccccca attgcaccaa tgtgtgctcc aacaaatgca ccagcaagtc cagctactcc
     1381 taaagtggcc aaacctgctc cagttccacc agttataatt cccgtagtga ctcctgtaat
     1441 cagtgcattt tgacaatcag tggagctata ccccccttca actttcgcaa gcatttcagt
     1501 atccataacc tctaactgtg acaacatttt tgtattcatg atgaatacct cctttttatt
     1561 ttcaatttgt taccaaagtc ttaaattcaa taaacaaata gattttttat agtatctttt
     1621 tgattttctt aaaaaagtat atacgtctac tatcttctta aaggtagcag tacctatttt
     1681 ttagtctaag atttcaataa tcttgagtat ctaaaatatc ttaatttcgt tattctcctt
     1741 gcaataaaaa gttttactat actatttatt aacttgcaga aagcaaaaaa tattagtaaa
     1801 taatagttta tagttaagtt ttttattcct accaatccat caactaagta aagcatcaac
     1861 gattacataa acgattgata atataattaa aattttgcta actatcttat tctcatcatt
     1921 cttagataac tttgatattt tgtaagtaag taaataagac agtaaattaa tagcgataat
     1981 aatactatat ttaagaatca taatcttaca aagaggacat aattcctgaa cctacacaaa
     2041 taagtgttgc tgctccccca gttatcggac cagtcgcagc agctaatagt actgctccaa
     2101 tacaaccacc gattgcagat cctaaattgc ctcttcctcc actaactatt tcgagttctt
     2161 cattatccat aacagaaaat tgttccatca tttttgtatt catgacaaat actccttttt
     2221 tcttttttta tttttgtctt gttgtaactt tgataagttt agtatatcat cgttttttaa
     2281 aatttttcat ccagatcttg aattgtcatc gaaacgtctt gaattagctt ttttatttca
     2341 agccacctct aaatgtttaa aaaaaataat ttctaatcac ttttttacca ttcaggaagt
     2401 tttaatgact attcaagatt tcataaaata tgaacttagt tttatgacat aatagaccta
     2461 tccactatat gaaaagaatt gccaatgact tcttataaac gtacatttgt tcctcaaata
     2521 gatgcgagag actgtggtgt cgctgcctta gcctcgattg ctaaattcta tggttcagat
     2581 ttttctctag ctcacttgag agaacttgca aagaccaata aagaagggac gactgctctt
     2641 ggcattgtaa aagccgctga tgaaatgggc tttgaaacaa gacctgttca agcagataaa
     2701 acgctctttg acatgagtga tgtcccctat ccatttatcg ttcacgttaa caaagaagga
     2761 aaactccaac attactatgt tgtctatcaa acaaagaaag actatctgat tattggtgat
     2821 cctgaccctt ctgtaaaaat cactaaaatg tcaaaagaac gctttttcta tgaatggact
     2881 ggagtagcta tttttctagc taccaaaccc agctatcaac cccataaaga taaaaagaat
     2941 ggtctactaa gcaagcttcc ttcctctgat tttcaaacaa aaatctctca ttgcttacat
     3001 tgttctctca agcttattgg tcactattat caatataggt ggttcttact atctccaagg
     3061 aatcttggat gaatacattc caaatcagat gaaatcaact ttaggaatca tctcagttgg
     3121 tctggttatc acctaggtta tcacctatat cctccaacaa gtcatgagct tctccagaga
     3181 ttatctccta accgttctga gccagagatt aagcattgat gtgattttat cctatattcg
     3241 ccatattttt gaacttccca tgtctttctt tgcgacacgt cgtacaggag aaatcatttc
     3301 acggttcaca gatgctaact ctattataga tgccttggct tctaccattc tttctctttt
     3361 tctggatgtt tctattctga ttcttgtagg gggagtcttg ctggcacaaa accctaatct
     3421 cttcctcctt tctcttcttt ccattcctat atacatgttc atcatctttt cttttatgaa
     3481 accttttgaa aaaatgaacc atgatgtcat gcaaagtaat tctatggtta gctctgccat
     3541 tatcgaagat atcaacggga ttgaaactat aaagtcgctc acgagtgaag aaaatcgcta
     3601 tcaaaatata gacagcgaat ttgtagatta tttggaaaaa tcctttaagc tcagtaaata
     3661 ttctatttta caaacgagtt taaagcaggg aacaaaatta gttctgaata tccttatcct
     3721 atggtttggc gctcaattag tcatgtcgag taaaatttct atcggtcagc tgattacctt
     3781 taacacactt ttttcttact ttacaactcc tatggaaaat attatcaacc tccaaaccaa
     3841 actcccatct gcgaaggtcg ctaataaccg tttgaacgaa gtctatctag tcgaatctga
     3901 atttcaagtt caagaaaacc ctgtccattc acattttttg atgggcgata ttgaatttga
     3961 tgacctttct tataagtatg gttttggacg agatacctta acagatatta atctcacgat
     4021 taaacaagga gataaggtta gcctagttgg agttagtggt tctggtaaaa caactttagc
     4081 caaaatgatt gtcaatttct ttgaacccta caaagggcat atttccatca atcatcagga
     4141 tattaaaaac attgataaaa aagtcttgcg ccgtcatatt aattacctac cccaacaagc
     4201 ctatatcttt aatggctcta tcttggaaaa tttaaccttg ggcggtaatc atatgattag
     4261 ccaagaagat attctaagag cttgtgaatt agctgaaatc cgtcaagaca ttgaaagaat
     4321 gcctatgggc tatcaaactc agctctctga tggagctggt ctatcaggag gacagaagca
     4381 acgaatagcc ctcgctcgtg ctcttttaac taaatctcct gttttaatac tagacgaagc
     4441 tactagcggt cttgatgtct tgactgagaa aaaagttata gataatctta tgtccctaac
     4501 tgataaaacc attctctttg tagcccatcg tctcagtata gccgaacgaa ctaaccgtgt
     4561 cattgttctt gaccagggga aaatcattga agttggtagt caccaagagt taatgcaggc
     4621 gcaaggcttc taccatcatc tgttcaataa ataaggagaa tgtcatgaat cctaatcttt
     4681 ttagaagcgt cgagttttat cagagacgtt accataacta tgcgacagtg ttaattatac
     4741 ctctttcatt actgtttact ttcatcttga ttttctccct tgttgccaca aaagaaatta
     4801 ctgttacttc ccaaggagaa atcgccccta caagtgtcat tgcatccatt cagtcaacca
     4861 gtgataatcc tatccttgct aatcatttag tggcaaatca agtagttgaa aaaggtgact
     4921 tactcatcaa atactctgaa acaatggatg agagtcagaa aactgcctta gaaactcaat
     4981 tacaaagact tgagaagcaa aaagaaggac ttggaatttt gaaacaaagt ttagaaaaag
     5041 cgactgatct tttttctggc gaggatgagt ttggctacca taataccttt atgaatttta
     5101 ctaaacaatc ccatgatatt gaactgggta tcacaaagac taacaccgaa gtttcaaatc
     5161 aagctaatct tgccaatagc agttcatcag ccatcgaaca agaaattaca aaagttcaac
     5221 aacaaattgg agaatatcaa gagttgagag atgctatcat aaataacaga gcacgcttac
     5281 caactggcaa tccgcaccag tcaattttaa atcgttatct tatagcctct caaggacaaa
     5341 cacaaggaac ggcagaggag ccatttttat ctcaaattaa tcaaagtatt gcaagtcttg
     5401 aatcatctat cgcaagcctc aaaattcagc aagctggtat cggaagtgta gcaacttatg
     5461 ataatagttt agcaaccaaa attgaagtac tccgcactca gtttttacaa acagcctcac
     5521 agcaacaact aaccgtggag aatcaattaa cagaattaaa agtacaacta gatcaagcga
     5581 cacagcgctt agaaaataat accttaaccg ctccaagtaa aggtatcgtt catctgaaca
     5641 gcgaatttga aggtaaaaat agaattccaa ctggtacaga aattgctcaa atattccctg
     5701 tcatcacaga tacaagagaa gtactaatca cttactacgt atcatctgac tatctcctct
     5761 tactagataa aggacaaact gtaagattaa aactggagaa gattggaaat cacggcacca
     5821 ccatcatcgg ccaacttcag agtattgatc aaactcctac cagaacagag caaggcaatc
     5881 tctttaaatt aaccgctctt gcaaaactat ctaacgagga tagtaaactc atccaatatg
     5941 gcttacaagg tcgcgtcact agtgtaacta caaagaaaac atattttgat tatttcaaag
     6001 ataaaatttt aacacattct gattaatttt cagataacac tctataacta tttattatct
     6061 tatcaaaaag gagaatcata acatggataa gaaacaaaac ctaacttcat ttcaagaact
     6121 aacaactacc gaactcaacc aaattatagg tggaggatgg tgggaagatt tcttatatag
     6181 atttaatata attgaacaaa aaaatacaaa aggatttcat cagccaatac aactataaaa
     6241 aaacaagacc aagagaacgc actctcggtc ttattttttc ttcattctat atgtattaca
     6301 gtaagtacct gacgaaaaac gtgatcttgg caggtggtat tgagactggt attgggatga
     6361 ctttccacaa ttttcataac ggtatagaga ccaactcctc tctcctcccc tttagaactt
     6421 gctccaaagg agaagatttc agaaatatcg attccctctt ctttgatgga attttcaatg
     6481 ataaaggtct cctgtgctcc attttttaaa aaggcaattg aaacatgagg ttgacaggct
     6541 tctacactag cttcaatagc gttgtcacaa aggatagaca caacggttag aaaatcaagt
     6601 agactcatcc cctctacctg aatctcctct ggaacttcga cattaaagac aatgttctta
     6661 tctctagctt ttagaaattt ccctgctagg agacttttga gggctttatc acgaatattc
     6721 accaatcgac caaggtcata tttattgtcc tgcaattttt cactagaatc ctttaagacc
     6781 gagtcgtaga tctcttttat ctgctccata tcctcctctt caatgcccag acgtaagcta
     6841 gtcaagaggt tggtgtagtc atggcgaaaa ctccgtactt ccttataaag ctcctctata
     6901 tgccgactat accgctccat ctctctgtag cgcaagtcct gctcttggtt cagtctctca
     6961 tggagtttgt ccttcaaata ggtatccaat ttcttgataa tccccataaa aaagagcagg
     7021 taaaagacta ggatgagatg gcgaacagtc gttgattgaa tcccctgttc atattcaaag
     7081 taagacagat tttgtatcac caaatagtaa gcccccatta tccagttaat ctgagtcagg
     7141 gacttttgaa aatctttatc gagaatcccc tttctcaagc tagtgaaatc atagtccaac
     7201 catttcaaaa aagctagaga aatgaagaaa ttgaaaatta ttatacataa ccaaataaat
     7261 gagtagtcat catatacttg cccttgtccc aaaaatggaa gcacaaaata ggaaacacct
     7321 ctataaaaga gattcactaa tatcattgga aagagaccat aaaagagaag gagtttttta
     7381 ggaagttctc ttaacaataa gaaagataag cctatgccgt acaagggttc cataaaataa
     7441 gatagataag tatttcctac catatagcca agcattccaa aaacaacggc caacagtatc
     7501 ttaaaaagaa aggccttaaa aatcctctca aaagtgagac taattccatc taccttaaag
     7561 aatatgacaa tttttaatcc gtgagtaaca agtgtataca acaatatcca agcaacattc
     7621 ataaactctc ctagctcagt gtaagttatt aatagcctca gacacttccc tgaccttata
     7681 acgcgcgatt agacaacttc caccattggg aaagaaaagc agtttttctt tcttatctaa
     7741 atgcaccaca ttggcaggat tgatgagaaa agagcgatgg cactgcaaga gacgaggctc
     7801 ctgcttgaga acctcctcta gactcgctgt aaattccagc ctgtctgtct tggtatagag
     7861 aataacacga tggggtcttg tggacgtttc gagatagtaa acctctttaa aaggatactg
     7921 gaattgagca aattttgatt taaagtaaaa gcaatcttcc gctagacttt tactgtcttg
     7981 accattggca tagaggaggg ctgtctcgat acgagattca aactcctctg ccgaaagggc
     8041 cttatcaata tagtccagag cagacacttg gtagcgaaag gacaggggca taaactccga
     8101 gtgagtcgtc acaaagacaa tcagggcata cggatcccga tcccgaatct ttctagccac
     8161 ttccagaccc ttcatctcct catttcgaat ctcaatatcc aaaaagaata gctgatgggc
     8221 ccccttctca tgcacctctg ccagcagttg gtctggcttg ccaaatacct caaaagagct
     8281 gggagtgata tgatgttcct tcaagagttt ctcaatcgtc gtttcaatcc tagtctgttg
     8341 ggaaaaatca tcctctaaaa caaatattct catcttctta ctctccctct ttcaaccatt
     8401 tttgacgaat ttctctatag cgacgtctgg catacttgac agcgtattga ccttcttctc
     8461 cgagaaaaag gattctttct tgaaaatcaa tcgattttaa tttatcaaga ttaaccaaac
     8521 aatttcgatg acatctcatc aaggtttccc catattggtt ctcaagatta cttaaatttt
     8581 gaagcatatt aaaactagct tcttctgtaa caatctgtac ggtatgggct ttagttggat
     8641 gtgtttggat atagtagata tcgtcgacgt ttactttata gactgttttc tgcgtctgaa
     8701 taatcatatg tttcattgga ttctcctcct aagaaaagaa taacagaaaa gttctagccc
     8761 aagcccaccc aatcctaaac agtctttgaa agctcctaaa aggattattt ttctacaaca
     8821 tcatgatgag cttacaacta ttttatcata aaattcactc agcgcaattc aagacatttc
     8881 aatgacaatt aaagatttga ataaaaaaaa agaattaaaa atgataaact aacagtatca
     8941 aaacacagtt gccagaagta agactggcac ccagattaaa ggaggcattc ccatgacaga
     9001 tacagacccc atcaaaagag ctcatacttt gattactgac ttaaacaaag cctaccaagc
     9061 atgcaaacag gcaagcgctg acgacgtccg ctttcaggag caattaaact ctattcttgg
     9121 ttttttagcc aaggctgaaa cagtggataa tcgattcttg attgaactag aaaaatttta
     9181 ccagacttcc agtcttctca tgggactcag cgctcttgat ccagatgctc caactcgcgc
     9241 cgcttggcgg gcctatgacc gcttccactt tgaccaagtc aagaccaagt taatactcaa
     9301 tgaaaatcaa agagcaaact aggaagctag ccgcaagctg tacttgagta cggtaaggcg
     9361 acgctgacgt ggtttgaaga gattttcgaa gagtataagt ctctacggac caaccattat
     9421 cctgtagtaa caaaaaagaa gctgagacag actgaactca acttcttttt tagtgtcgta
     9481 tcagcaatgt tagtcctgca tctgacgttt tacctgataa ggcaaataca agactagtaa
     9541 aaccaaacca gctcctagta aggctagaag ggccagtttt tcttggaagg taatcaaccc
     9601 aacaactaat tccacaagta aaacaaaact ggtcaatcct cgaactacct cctgtaagcc
     9661 tttttccttt tgccccttgt ccagcggaaa gagttgggtc aaatactggt agtcaaaggc
     9721 atgatagagg gccagcaact ggaagagcaa gaggtagtta aagagaacta ccactgctgt
     9781 cgcaatccaa gcttgctcga taaaaacctg cgccagtacg gaaagtaata gaagacgaag
     9841 actgagagca aagaggtcgc catttcgcag ataagaacgc agatagagat tttgccaaat
     9901 cttcccaggc accttctgaa cagcctttaa gataaagtcc agataggcac gacgcttaac
     9961 gctgtttgaa attcccttga cctgcgtaaa gagggcaaag aaacgaagca agacttgctt
    10021 acgcttgctt tcttgagaaa taacatagtc ccagtccagt ccagtttcag taaaaaattt
    10081 gctggccttt tgacgaaagt ggaaatattt tcctaccccc aataaaagca catatagcag
    10141 aaaaactggc aagccataac ccattgctaa aaataaaggc gcaaataaca gcaagaaaag
    10201 ggtctgtaca aagagccaaa agactaggga aatgccagtt tgacgcttga gatggagctt
    10261 gattgcctct tctccaacta agagaaagag cttgtctgga gcctccatat aggtggcaat
    10321 tcctccccaa agtaagagta aaacagacgt aattcctaca aacaaaagga taggccaatg
    10381 attttcagga aaatgttgta agagttgact gtactggtag gctagaaagc ccaacaggac
    10441 aagcaggaac aagacaaagt ggtcattgag cacatagcgc agataacaaa gacactcctt
    10501 acgaaaggcc tgctttctct ttaaaaacaa gtctttcata gatcctcctc tttggtcaga
    10561 gccaagtaaa tatcattcaa actagcctca ggcatatcaa aggcttcacg tagttgcagg
    10621 agattgcctt tggcacgcac ctctcccttg tgaagaatga caaaggcatc acacatcttt
    10681 tccgccgaat ccagcacgtg ggtactcatg agaatagact tgcccttttg cttctccact
    10741 tccaaaagct gaatcaaatc agaaatagcc agcggatcaa gaccaaggaa aggctcatcc
    10801 acgatgaaaa gacttggatc caccacaaaa gcacagataa tcatgacctt ctgcttcatc
    10861 ccttttgaaa aatgaacagg gaaccagtct aatttctgtt ccaaacggaa catttttaac
    10921 aagggctcta ctcgttcgaa agccactttt tgctcaatac cgtaagccat agcaaccgtt
    10981 tcgatatgct ctctgagggt caattcctca tacagactag gcgtctcagg aatgtagcca
    11041 atctgcttgc ggtagctagt cgcatctcct tgcagagtca ggccattgat attgatggag
    11101 ccactataag gtgccaacag accgataatc tcattgatcg tcgttgattt cccagcacca
    11161 ttgagaccaa tcaaaccgac caactgccca ctttcaacag taaaggacac atctttcaaa
    11221 acaggaacat gaacatagcc acctgtcagg tttttaattt ctaacatatt ttctccaaat
    11281 ctggtataat gtagctatat tatatcaaaa ttcagtacag tagaggtaga ttttatgtca
    11341 gattgcattt tttgtaaaat catcgcaggg gaaattcctg cttcaaaagt atatgaagat
    11401 gagcaggtcc ttgcctttct tgatatctct caagtaacac taggacacac cttggtcgtg
    11461 ccaaaagaac actatcgcaa tcttttggag atgaatgcta cgagcgccag ccaactcttt
    11521 gcccaagtac caaaagtagc tcaaaaagtc atgaaagtca ctaaggctgc tggtatgaat
    11581 atcatttcca actgtgaaga agtcgctggt caaacagttt ttcatactca cgttcacctt
    11641 gtgcctcgct acagtgctga cgatgacctc aagattgatt ttatcgccca cgaaccagac
    11701 tttgacaaac ttgctcaagt cgctgaaacc atcaaaaacg cttaaggagt tgctatgaaa
    11761 ttatccaacc tactgctatt tgcaggagct gcagccggaa gttatctggt tacaaaaaat
    11821 cgccaaacca tcacagatga agtcttgaat accactgacc gcgttcaagc tatcaaagac
    11881 gatgtggata ttatccaaaa tagcctgcaa atcatcgacc agcaaaaaga acttatcaag
    11941 gaataccaag aagacttgac ttacaagttt aaggtcttgg aaaaggatat ccagactaga
    12001 ctagctgtga taaaagaaat gcagggaact gaagataagt aaaaagagcc ccccggctct
    12061 tttttaaaac gtaaacaagt tatagtgaat tgaatttaga atagcacatc atagtttcta
    12121 aagcattgtt agagattact ttaaaatcct cttatcaatt tgttcatatt ctatttcaat
    12181 ctactatata tatcccatca actatgcatc ataatttagg taactcatac tcaataaaaa
    12241 tcaaaaagca aactagaaag ctaggcacag actgctcaaa acaccgtttt aaggttgtgg
    12301 atagaactga cgaagtcagc tcaaaacact gttttgaggt tgtggataga actgacgaag
    12361 tcagtaacca tacccatgac aagccgacgc tgacgtggtt tgaagaaatt tttgaagagt
    12421 atcattcacc atttcacaac taaatcgaag actttctgcc gtaatgaaaa cacctgaaac
    12481 agcttggttt cagctgtccg gaaactttaa gacttaggtt caaagtttag gtatggaact
    12541 tcgaaggagg tcgctaccgt ccgtcattac ttaggaaagt cttaaaaaat ctataaagta
    12601 aaaagagccc gacagctctt tttgtttata ctcaatgaaa atcaaaaagc aaactaggaa
    12661 actagccacg ggctgctcaa aacactgttt tgaggttgta gatacgactc acatatatac
    12721 ggcaagccga cgctgacgtg gtttgaagag attttcgacg ctgacgtggt ttgaagagat
    12781 tttcaaagag tattattctc catcaaaggc atctttaata tggtcaaaga agcctttttt
    12841 ctttggattt actttcaagt caccagcagc cgcgaattct ttcaaggcta ctttttggcg
    12901 gtcgttcaag cctgtcggtg ttacgacatt aacagtaacg tattggtcac caactgcacc
    12961 gccacgaagg ctcggtgccc ccttactacg taggcggaat ttcttaccag tctgagttcc
    13021 ctctggaata accaattcaa catcaccgtg aacagttgga atatctactg tatcaccaag
    13081 agccgcttgg acaaagttga ggttgagatt gtagaagata gtcgttcctt cacgttcaaa
    13141 cttgtcgcta gcttctacag aaactactac atacaagtcc ccataaggtc caccgttaaa
    13201 gcctgcttcg ccttgaccag cgaggcgaat ttgttgacct gtttccacac cagcagggat
    13261 tttcacatgt acgctatgag cttgtttctc atgacctgtt ccatgacagg ttgtacatgg
    13321 atatttgatt tcttttcctc gaccgtgaca gacatcacag gttacttggc gacgcatcat
    13381 accaagagga gtctgcgtat cgacgttaat gacaccagcg ccatgacagc gtccacaagt
    13441 gactggactt gtccctggct tagcaccaga gccattacat gtacgacagc cagcttcacg
    13501 atgatactta acttccttct cagttccgaa gatagcttct tcaaaggtca aattgacacg
    13561 atactggaga tcatctcctt ggcgaggagc gtttggattg cgcgaagaac cgcctccgcc
    13621 gaagaaactt gaaaaaatat cctcaaaacc accgaagcca cctgccccat tgaaaccacc
    13681 gaaaccacca gctccaccaa aaccaccatt ggcgcctgca gcaccatact ggtcataggc
    13741 agcacgtttt tggtcgtcac tcaaagtctc ataggcttct tgaacttcct tgtacttgtc
    13801 ctcagcacca ggctccttgt tgatatctgg gtgatatttt ttggaaagct tacgataagc
    13861 ctttttgatc tcgtctgccg aagcgttttt tgacaccccc agacgatcat aaaattcagt
    13921 attgttcata caagatacca agaccgtaaa attcgactga aaaataggaa atctgacgct
    13981 ggagcgacgc tcctagacag atttctcttt tttccgagaa tttaggtcgg gttcaattcc
    14041 tttcttttat attgatgaga taatactcca gccactcggc cctatccctt tttaccgaaa
    14101 aacagaggct gagttgcaac ctctgtggtt agattattca tttgaaataa aaatggttgt
    14161 attatctcta gtagtaatct tcaaagacct tttagctaaa tcaaactcaa atttattata
    14221 gtgtgggtct tgtgttttat ataggtgtaa ctcctgacat atatgatccg aaaagtaaat
    14281 cataacatct ttaaacacag aagtgtggtc atatttactc ttaccaacag ctacttctgt
    14341 aaattcttta taaatgacat ttccatttct ttccacagtc accagcattt ctgttggatt
    14401 ataatccaaa ttaaataatt cttcaaaaaa ctttatcttt tcatgataat ctgcaatgtc
    14461 agaaagatta tttttattaa cactcataac actagcccct tatttttcag taaactctcc
    14521 gtctacgacg tcatcgcctg cgtttcctgt tgcttgtgcg ccttctgctc cttcttgagc
    14581 ttgttgcgct gctgcagctt gttcgtagag tttaacagca agtccttgag ctttttcgtt
    14641 caatgcttca agttttgctt tcatgtcgtc caagttgttg tcttcttgag ctttcttaag
    14701 gtcatcaagg gcagcttggg cagcgtcacg ttctgcgtcg aagcctttac cttcagtttc
    14761 cttgattgtc ttttcagtcg caaagattgc ttggtctact tcattacgaa ggtctacttc
    14821 ttctttacgt ttcttatcgg cttcagcgtt tgcttctgca tctttcatca tgcggtcgat
    14881 ttcttcgtca gtcaaacctg agttcgattg gatgacaata gtttgttctt tttgagttcc
    14941 aaggtctttg gccttaacag acacgatacc gttcttgtcg atgtcaaatg ttacttcgat
    15001 ttgaggaatt ccacgaggtg cagctgggat atcagtcaat tggaagcgtc caagagtctt
    15061 gttatctgct gccattgggc gttcaccttg aagaacgtgg atatcaacgg ctggttggtt
    15121 gtctgctgct gttgagaaga cttgtgattt agatgttggg attgtagtgt tgcgatcgat
    15181 aagttttgta aatactccac ccattgtttc gataccaagt gacaatggcg ttacatcaag
    15241 aaggacaacg tccttgacat caccagtaat cacaccacct tggatagccg cacccatagc
    15301 aactacttca tcagggttta ctgatttgtt tggttcttta ccagtttcag ctttaacagc
    15361 ttcaacaacg gcagggatac gagttgaacc accaacaagg ataacttcgt cgatttctga
    15421 caagctcaaa cctgcatctg aaagggcttg acgaactgga acttttgtac gttcaacaag
    15481 gtcacgagtc aaatcgtcaa atttcgcacg agtcaaagtc atttccaagt gaagaggtcc
    15541 agcctcacct gcagtgataa atggcaagct gatttgtgtt gaagttacac cagaaaggtc
    15601 tttcttcgct ttttcagccg catctttcaa acgttgcatt gccatcttgt cagtagacaa
    15661 gtcgataccg ttttctttct tgaattctgc taccaagtgg tcaatgattt tttggtcaaa
    15721 gtcgtcacca ccaagtttgt tgtcccctgc agttgacaat acgtcgaaga caccgtcacc
    15781 caattcaagg atagagacgt cgaatgtacc accaccaagg tcaaatacca agattttttc
    15841 ttctttgtca gtcttgtcca aaccataagc aagagctgct gcagttggtt cgttaacaat
    15901 acgttctact tcaagaccag caattttacc agcgtctttt gttgcttgac gttgagcgtc
    15961 gttgaagtaa gccggaactg tgataacagc tttggttact ttctcaccaa ggtagtcttc
    16021 agcgtagcct ttcaagtatt gaaggatcat agctgagatt tcttgtggag tgtattcttt
    16081 tccatttgca gaaacttttt cagaagttcc catcttagat ttgatagaga taactgtatc
    16141 tgggtttgta actgcttgac gttttgcagc atcaccaacg atgatttctc cgtttttgaa
    16201 tgagactaca gatggagttg tgcggtttcc ttctgggttt gcgatgattt tgctttcagt
    16261 tccttcaaga actgcaactg ctgagtttgt tgtacctaag tcaataccga taattttaga
    16321 catgtgtttt tctccttgtt agttaatttt ctatttttct ttttgatact cttcttaagt
    16381 ggcgacgccg tcagagcttg acttcgtcaa tctctttgac taaactttga gcctaaggtc
    16441 tcaaaatttg cgcaaatagc accacggcga agagtatcgt ctttggttcg cttcgctcac
    16501 tattacaaag ccaaacatat tttatctttc ttcatagttt attgtcgttt cggacaagtt
    16561 ttctattatg taaattgcga cacgaggagt cgaaatcgat tttatttcga cgacgagtta
    16621 gtaaggaagc taggcaaacg tcatagcgat tgccgttttc tgacgagttg ctttagctac
    16681 cgtcagaatt gccgaatcga acacgcccta agctctgagt aaaaaagata gattttcttg
    16741 tgttcatcga acacttcgtc aatctcctat ttttactgcg agctttttac gagctttgta
    16801 tcttagttat acaccactac cattgctggg cgtaggatgc ggtcatggag tttgtagcct
    16861 ttttgaaaga cttgggcgat ggtatctact gggtgttcat cgtctgctgg gagagtttgg
    16921 atggccatat ggtagttatg gtcaaattcg ccatctgctg cgatttcttc aattccttct
    16981 tctttcaaag cgtgaatcaa gctttcttgc accatcccca agcccttctt cacatcatct
    17041 gtcaaacctt caactgcaag tgcacgctca aggttgtcaa gagatggtaa gattgctttt
    17101 gccaagtcct ggctacgata acgttgcaag ttttgacgtt cttcattggc acggcgttgg
    17161 atattttgca tttctgcatg agcgcgaaga tatttgtttt cgaactcatc tgcacgttca
    17221 tttgccaagt ccaactcaga cttttcagga gttgtttctt cagctgtttc cacaacttcc
    17281 tcttcttgaa cttcttctac ttcttcattt tttatatctt gggccatgtt cgcctccttt
    17341 aatgatttca atcttaatgt acttcgtaat gattactgct gaggtagcgg taaaaatctg
    17401 tcaacttcat ggtcaaaaca cggttgacca cattgacttg attgattagc tgttggtaat
    17461 ccagattaac tggaccgata atggctagaa ttccaactcc ccgataagga atgaggaact
    17521 tactactaat caccgctagg tcagctaaac aggactcttg accgtctgca acacgaacat
    17581 tttgcatctg atcctcacgc aacccctcac gaatctccaa ggccaccttt tgcggttggt
    17641 caaagaactg ataggcttct agattggcaa aattcaagag attgaccttg cccgccatca
    17701 caatgttttc gttgaacatt tccttaaaga tgtgttcaaa gagatcgatg acattatccg
    17761 ttgttgtaaa gtaacgctgg ataatctgcg gaatctccgt ccgaatcttg tagtgaatat
    17821 ctaaaacggt gtgaccgagg aaacgttcct gaatgatgct cttcagtttc agcaaatcct
    17881 cctgcaagaa gttccttgga atcagaaact gactagtaac cgttcgcgac tcgtctaggg
    17941 taaataccgc caaggctgta tgttgcccca aaacaacgat atcaaaggct gtcaaacgtt
    18001 gcctgctcgg ctcaacatcc agtgccacta ccgtacagcc actcaggcct gttagcaagt
    18061 tagcagcctc ttgcagaata tcctccaatt tgaagaattc ctgatcaaag gctttgacaa
    18121 tctcatatac ctcattttca gccagccggt gaaaatccag tgagtgtttc acatagtact
    18181 gaaaaccagc aacacttggc atccgaccgc ttgaagtatg agccttctca agcaaccctt
    18241 gtttttctag ttccgccatg tcattacgaa tggttgcact gctagagtta atagactctt
    18301 gcaaggcttt tgatccgaca ggttcgtgcg ttttggtaaa gatgtcaata atcagattta
    18361 aaatatcctg ctgacgctct gtaaccatct catcactcct ctctgtctga tcaattagca
    18421 ctcaatgcat ccaagtgcta acttatgatt ctattataca cccttaaaag agaatgtcaa
    18481 gacaaaaact caaaaaatta gcactctttt atcaagagtg ctaaaaatca atctgaagac
    18541 ctagaacctt gctattcatc tactcggtat ttccttttta gtctgaaata accatgaatt
    18601 agataagaaa tcagaaaagc atataaaaca aaaataagaa agaaagacat agaaagatcc
    18661 tctctaaaca aactcgtaca aacaacaaga ccacctaaga aagtagttgt acaggaacga
    18721 agtctagatc gcataacttc ccatttgagc cccttactca tatagacttg atcctctgga
    18781 agtaaatcag aagacgattt acgaagaatc gaacaagaac ctgctcctat caattcccaa
    18841 cctctatctc taaaatcttg cagttcatgc ttatattttt taagaaatct agaatcatag
    18901 atacggtaga tgacatcgtc tggttgacat tggtcaaaat agaacaaacc aaaacgactc
    18961 gttctatacc tccaaccttt caaatgcatc tcatgtaaat attcttcttc cttgtccaaa
    19021 tcaacaatgg tgaaaatccg aaattctact ctgctattca ttgtcttacc ccaaaattag
    19081 aaaacatgcc tggcgttatt tattagataa ttctttccac ttttgactca atctccaaaa
    19141 aatataagaa atctgaatcg caaaaactat caataaaacc caatctatta tgaaaatcaa
    19201 aaacactttc caactgaaag aactacctcc agtgacaaac tttgagcaaa acggtagtag
    19261 agctaaaaag agaagtaaaa taggaagcat ccgcattgtt aaaatccgtt tggcataaaa
    19321 aaatctttat ttaaactaaa atattatagc aaaatttacg ccagtttttg aacggctgat
    19381 gtagatattt tatactttca aaatgtttaa atgtgattat ttatttttga aaaatagctc
    19441 accagcccga ctgaaagtgc ttatagaatg ataataagtc gcctgccgaa aacagcggaa
    19501 aatagcggtg ttatgcggag ataatctgac gcgatgcgaa agtatattgc atacttattt
    19561 tcaacaattt agcagagtat ttttataagt gtgatataat agaagtataa tttgttctga
    19621 tagtttattt tatggagaag tagattttta gaatgcggag ggttcaatat ggttgagttt
    19681 ataaagtcta agaaagaaat gagtgaggag gatattaaag caaatttcat cactcctgct
    19741 attgtatcca aaggatggaa aaatggtgag catatcgctt acgaagaata cttcactgat
    19801 ggtcgaattg aggttagagg agataaggct cgtcgtaaag aaggaaaaaa atcagactat
    19861 tcactgtatt accaatttgg aactcgaatt gcaattgttg aggcaaagga taataaacac
    19921 agcgttcgag caggattaca acaagctatt gaatatggag agattttaga tgttccattt
    19981 gtttattctt cgaatggtga tggctttatt gaacacgacc gtatcacgag agaagaacgt
    20041 gagctggagt tagacgaatt ccctactcgt gaagaattat tttctcgtat gacgaaggaa
    20101 aaaggattga cgtacgaaat tacagaagct atctcaactc catactatac agacgccttc
    20161 tcaatgaaaa cgccacgcta ttatcagcaa atagctatca accgtactat tgaaacagtt
    20221 gccagaggac aaaaacgagt aatgtttgtg atggcaacag gaacagggaa aacgttcatg
    20281 gcttttcaaa ttattcatcg ccttcgaaaa gctggtttgg ctaaacgagt tttattctta
    20341 gcagatagaa acatcttagt agaccaaacg atggctgaag actttaagcc attcgaaaag
    20401 gtaatgacga aaattacacc aaaacttttg actgctcctg aaaaattaaa ttctttcgaa
    20461 atttatctag ggctttatca gcaactaact ggtgaagatg gaactgaaac acattatcaa
    20521 aaatttgaca aagacttctt tgatttaatc gtaattgatg aagcgcaccg tggttcagct
    20581 aaggaaaaca gtaactggcg taaggtaatt gattatttca gttctgcgac acagattggg
    20641 atgaccgcta ctcctaaaga aaccaagaat gcttccaata cggaatactt tggtaagcca
    20701 atctatactt atagtttaaa acagggaatc gaggatggtt ttttggctcc atatcgtgtt
    20761 atgagggtta atttagatgt ggatgtggat ggttatcgtc cagaaactgg aaaagttgat
    20821 gctaacggac aattaataga agataggtac tacggcagga aagattttga taaaaccatt
    20881 gtcattgatg atagaacgca aagagttgcc aagtttgttt ctgattatat gaagcaaaac
    20941 aatgcacgat ttgataaaac aattgttttt tgtgttgata ttgaccatgc cgagcgaatg
    21001 cgtgctgcac ttgtaaaaga gaatctagac ttagtccaag aagactatcg ttatgtcatg
    21061 caagtaactg gtgacaacgc tgaaggaaaa gctcaactgg ataactttat ggatgtcaat
    21121 tctaattttc ccgctattgt aacaacgtct aaattattaa cgacaggagt taatgctaaa
    21181 acatgtcgtt tgattgtttt agactctaat atccaatcca tgactgaatt taaacaaatt
    21241 attggtcgtg gcacacgtct ttatcctcaa aaggggaaag aattttttac gattattgat
    21301 tttcgaaatg ttaccaattt gtttgctgac cctgattttg atggtgagcc agtgaaggtg
    21361 ctggaaacag gtgcgaaaac agtcagtggt tctacgcctg gtttcgtagg tgaggaaggt
    21421 gacccagtag aaaaatatat cgttacagac aagcaggtta ccattcttaa ttctactgtt
    21481 caagtattgg atgaaaacgg gaaactgatt accgaaagcc tgaccgacta cactcgaaag
    21541 aatatcttag gtagctacgc cactttgaac gattttatca cagtttggca tacggcagat
    21601 aagaaacatt atgggaagtt tgctgatgga agcactcaag aaattgatgt tccttatgat
    21661 attcctgata cttgggagtg ggtgaggttt tctacattgg ttgaaattgt cagaggtggc
    21721 tctccacgac caatcaaaga ttatcttact tctgaagtag atggaataaa ttggataaaa
    21781 ataggtgata ctgaaaaggg tgaaaagtat ataaataatg ttaaagaaaa aatcaaaaaa
    21841 tcagggctta acaaaactag atttgtaaaa aaaggtacat ttttgttaac taattctatg
    21901 agttttggta gaccttatat tttgaatgtt gatggtgcaa tacacgatgg atggttggct
    21961 atttcgaact atgaaaactc attaaataaa gattacctat tctatattct ttcatcaaat
    22021 gtagtttatt ctcaatttct atctctaatt agtggagctg ttgtgaaaaa cttgaatagt
    22081 gataaagttg cttctattct tatc
//
LOCUS       DAVBBO010000034        22017 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ST1
            SAMEA2066453-rid20184263.denovo.034, whole genome shotgun sequence.
ACCESSION   DAVBBO010000034 DAVBBO010000000
VERSION     DAVBBO010000034.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2066453
            Sequence Read Archive: ERR351777
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 22017)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 22017)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980402.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980402.1
            Genome Coverage       :: 176x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:17:33
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,141
            CDSs (total)                      :: 2,104
            Genes (coding)                    :: 1,953
            CDSs (with protein)               :: 1,953
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 16S)
            partial rRNAs                     :: 1 (23S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 151
            CDSs (without protein)            :: 151
            Pseudo Genes (ambiguous residues) :: 0 of 151
            Pseudo Genes (frameshifted)       :: 73 of 151
            Pseudo Genes (incomplete)         :: 76 of 151
            Pseudo Genes (internal stop)      :: 40 of 151
            Pseudo Genes (multiple problems)  :: 32 of 151
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..22017
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2066453-rid20184263.denovo.034"
                     /strain="ST1"
                     /db_xref="taxon:1313"
     gene            51..233
                     /locus_tag="VQU30_001312"
     CDS             51..233
                     /locus_tag="VQU30_001312"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000842022.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helicase"
                     /protein_id="HET2447418.1"
                     /translation="MKSQKIKVSFTQSKIVTPILLVNKTIVWYGAMPLLGKVDEMTIL
                     RLESASIVSELVAGLR"
     gene            533..1372
                     /locus_tag="VQU30_001313"
     CDS             533..1372
                     /locus_tag="VQU30_001313"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006270038.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HET2447419.1"
                     /translation="MIIKRILNHNAVIAQSKKDIDILLFGRGIAFGRKTGDKVNPIDI
                     EKSFFLKNRDNMTRFTEMFINVPLELVYITEKIINLGKITLGNNFDEIIYINLTDHIS
                     SSIERYKEGIIISNPLRWEISKYYKEEFELGKRALQIIKKELGIELPIDEAAFIALHF
                     VNANLENNFQESYKITEIIMGIEKIIQDFYCTEFNQDSIDYYRFITHIKLFAHRLVEN
                     TTYCDDDDEDLLALMKNKYPREYECGEQVAMFIQTEYNYLLTSSELVYLMAHIRRLTK
                     NLD"
     gene            1390..3228
                     /locus_tag="VQU30_001314"
     CDS             1390..3228
                     /locus_tag="VQU30_001314"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000120564.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HET2447420.1"
                     /translation="MSYKDTVQKILDVIGGEKNVNRVTHCVTRLRLELKDENLVNDDD
                     VKKIPDVIGIMKKNGQYQIILGNDVANYYKEFVKLGNFESDSVVQGHKGNILERIIEY
                     IAGSMTPIIPAMLGGGMLKVLVIILPMLGILQSDSQTIAFLTFFGDAPYYFLPLLLAY
                     SASQKLKVTSTLAMSVAGVLLHPNFVQMVQSGNPLSLFGAPVTPASYGSSVVPILIMV
                     WLMKYIEKIIAKLTPAITKSFLQPTLVLLVSSCIALVVVGPIGVIVGEGLSNLVGQMY
                     GVAGWLTLAILGAIMPFIVMTGMHWAFAPIFLAASIATPDVLILPAMLGSNLAQGAAS
                     MAVALKSKNNNTKQIAFAAGFSALLAGITEPALYGVTLKYKKPLYAAMIGGGLAGLFA
                     GLTSVKAYLFAVPSLIALPQFIYSDVPSNIVNALIVAVISVVITFVLAYIFGIDEEES
                     SSNLEVKAGVSNKKMIFSPISGEIIPLSDVQDKTFSDKLIGDGVAIIPSEGKVYAPFD
                     GKITNIFPTKHAIGLKSDEGVELLIHIGLDTVELKGQGFISHVEEGDRVFKNQLIFEM
                     NLNLIKTKGYETVTPVIVTNTNDFLDVLVLPNNQTIEHSKELLVIL"
     gene            3241..4656
                     /locus_tag="VQU30_001315"
     CDS             3241..4656
                     /locus_tag="VQU30_001315"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000151865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HET2447421.1"
                     /translation="MTIFPDDFLWGGAVAANQVEGAYNEDGKGLSVQDVLPKGGLGEA
                     TENPTEDNLKLIGIDFYHKYKEDISLFSEMGFNVFRTSIAWSRIFPKGDEEEPNEAGL
                     KYYDELFDELHAHGIEPLVTLSHYETPLYLARKYHGWIDRRMIHFYEKFARTVLERYK
                     DKVKYWLTFNEVNSVLELPFTSGGIDIPKENLSKQELYQAIHHELVASSLVTKIAREI
                     NSEFKVGCMVLAMPAYPMTPNPKDVWATHEYENLNYLFSDVHVRGYYPNYAKRYFKEN
                     DINIEFAAEDAELLKNYTVDFLSFSYYMSVTQSAIPTQYNSGEGNIIGGLVNPYLESS
                     EWGWQIDPIGLRIILNRYYDRYQIPLFIVENGLGAKDQLIKDELNNLTVQDDYRIQYM
                     KEHLLQVAEALQDGVEIMGYTSWGCIDCVSMSTAQLSKRYGLIYVDRNDDGNGTFNRY
                     KKMSFTWYKGVIESNGESLFK"
     gene            5248..6294
                     /gene="pheS"
                     /locus_tag="VQU30_001316"
     CDS             5248..6294
                     /gene="pheS"
                     /locus_tag="VQU30_001316"
                     /EC_number="6.1.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013903845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phenylalanine--tRNA ligase subunit alpha"
                     /protein_id="HET2447422.1"
                     /translation="MSTIEEQLKALREETLASLKQITAGNEKEMQDLRVSVLGKKGSL
                     TEILKGMKDVSAEMRPIIGKHVNEARDVLTAAFEETAKLLEEKKVAAQLASESIDVTL
                     PGRPVATGHRHVLTQTSEEIEDIFIGMGYQVVDGFEVEQDYYNFERMNLPKDHPARDM
                     QDTFYITEEILLRTHTSPVQARAMDAHDFSKGPLKMISPGRVFRRDTDDATHSHQFHQ
                     IEGLVVGKNISMADLQGTLQLIVQKMFGEERQIRLRPSYFPFTEPSVEVDVSCFKCGG
                     EGCNVCKKTGWIEIMGAGMVHPRVLEMSGIDATVYSGFAFGLGQERVAMLRYGINDIR
                     GFYQGDVRFSEQFK"
     gene            6294..6803
                     /locus_tag="VQU30_001317"
     CDS             6294..6803
                     /locus_tag="VQU30_001317"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000619935.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HET2447423.1"
                     /translation="MIRKVEMADVEVLAKIAKQAFRETFAYDNTEEQLQEYFEEAYSL
                     KTLSTELGNPDSETYFIMHEEEIAGFLKVNWGSAQTERELEDAFEIQRLYVLQKFQGF
                     GLGKQLFEFALELATKNSFSWAWLGVWEHNTKAQAFYNRYGFEKFSQHHFMVGQKVDT
                     DWLLRKKLR"
     gene            6880..9285
                     /locus_tag="VQU30_001318"
     CDS             6880..9285
                     /locus_tag="VQU30_001318"
                     /EC_number="6.1.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002897790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phenylalanine--tRNA ligase subunit beta"
                     /protein_id="HET2447424.1"
                     /translation="MLVSYKWLKELVGIDVPSQELAEKMSTTGIEVEGVESPAAGLSK
                     IVVGEILSCEDVPETHLHVCQVNVGEEEERQIVCGAPNVRAGIKVMVALPGARIADNY
                     KIKKGKIRGLESLGMICSLGELGISDSVVPKKFADGIQILPENAVPGEEVFSYLDLDD
                     EIIELSITPNRADALSMRGVAHEVAAIYDKAVNFKEFTLTETNEAATDALSVGIETDK
                     APYYAARILDNVTIAPSPQWLQNLLMNEGIRPINNVVDVTNYILLYFGQPMHAFDLDT
                     FEGTDIRVREARAGEKLVTLDGEERDLDVNDLVITVADKPVALAGVMGGQATEISEKS
                     SHVVLEAAVFNGKSIRKTSGRLNLRSESSSRFEKGINVATVNEALDAAASLIAELAGA
                     TVRKGIVSAGELDTSDVEVSSTLADVNRVLGTELSYADVEDVFRRLGFGLSGNADSFT
                     VSVPRRRWDITIEADLFEEIARIYGYDRLPTSLPKDDGTAGELTVTQKLSRQVRTIAE
                     GAGLTEIITYVLTTPEKAVEFTAQPSNLTELMWPMTVDRSVLRQNMISGILDTVAYNV
                     ARKNKNLALYEIGKVFEQTGNPKEELPNEINSFAFALTGLVAEKDFQTAAVPVDFFYA
                     KGILEALFTRLGLEVTYTATAEIASLHPGRTAVISLGDQVLGFLGQVHPVTAKAYDIP
                     ETYVAELNLSVIEAALQPAAPFVEITKFPAVSRDVALLLKAAVTHQEVIDAIQAAGVK
                     RLTDIKLFDVFSGEKLGLGMKSMAYSLTFQNPEDSLTDEEVARYMEKIQASLEKKVNA
                     EVR"
     gene            complement(9458..10459)
                     /locus_tag="VQU30_001319"
     CDS             complement(9458..10459)
                     /locus_tag="VQU30_001319"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000597989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease/exonuclease/phosphatase family
                     protein"
                     /protein_id="HET2447425.1"
                     /translation="MIKTFLSALSVILFVIPIITYSFFPSSNLNIWLSTRPILAQIYA
                     FPLATATMAAILSFVFFSLSFYKKNKQIRFYSGILLLLSLILLLFGTDKTLSSASNKT
                     KTLKLVTWNVANQIEAQHIERIFSHFDADMAIFPELATNIRGEQENQRIKLLFHQVGL
                     SMANYDIFTSPPTNSGIAPVTVIVKKSYGFYTEAKTFHTTRFGTIVLHSRKQNIPDII
                     ALHTAPPLPGLMEIWKQDLNIIHNQLASKYPKAIIADDFNATMRHGALAKISSHRDAL
                     NVLPPFERGTWNSQSPKLFNATIDHILLPKNHYYVKDLDIVSFQNSDHRCIFTEITF"
     gene            10615..11103
                     /locus_tag="VQU30_001320"
                     /pseudo
     CDS             10615..11103
                     /locus_tag="VQU30_001320"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001155321.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
     gene            11187..11453
                     /locus_tag="VQU30_001321"
     CDS             11187..11453
                     /locus_tag="VQU30_001321"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001808618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HET2447426.1"
                     /translation="MEGCPSELFSKEEILESDMRVAIMSELIEARYEQGISQKKLEEV
                     SGVSQPVIARMETGESSLQLDTVLKVLTSLGKTLAVVPLEQGKS"
     gene            11714..13963
                     /gene="metE"
                     /locus_tag="VQU30_001322"
     CDS             11714..13963
                     /gene="metE"
                     /locus_tag="VQU30_001322"
                     /EC_number="2.1.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009729869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-methyltetrahydropteroyltriglutamate--
                     homocysteine S-methyltransferase"
                     /protein_id="HET2447427.1"
                     /translation="MSTTIIGFPRLGEFRELKFTTEKYFRKEISEEELLAAAKDLRAK
                     HWNIVKEKGITEIPSNDFSHYDNFLDAAFLFNVVPASVQNLDLSDLERYFALGRGYQG
                     EKGDVRALPMKKWFNTNYHYIVPKFEKDTQVKLAGHKIFDEFQEAKELGLNTRPVLVG
                     PFTFLQLSDFEEGVKADDFVDSLVAAYQEVFAKLAELGATRIQLDEAALVKDLTAEEK
                     ALFLNLYNKLLADKKGLEVLLQTYFGDVRDVYADLVNLPVDAIGLDFVEGKKTLELVK
                     GGFPADKTLYVGIVNGKNIWRNNYEKSLAVLEQIPAENIVLTSSCSLLHVPFTTANEE
                     FEPALLNHFAFAVEKLDEIRDLDAIRNGQGSEALAANKELFATERVGENAELRARIAG
                     LTDADYTRLPAFAEREAIQEEAFKLPALPTTTIGSFPQTKEVRAKRLAYRKGELSQKE
                     YDAFLAETIDEWIKWQEDIDFDVLVHGEFERNDMVEYFGQNLSGYLFSKNGWVQSYGM
                     RGVKPPIIWGDVTRLNPITVKWSSYAQSRTNKPVKGMLTGPVTILNWSFPREDISIKD
                     STLQIALAIKDEVLDLEAAGVKIIQIDEAALREKLPLRRSDWYEDYLDWAIPAFRLVH
                     STVASDTQIHTHMCYSEFTDIIPAIDNMDADVISFEASRSNLEILDELKAKNFQTEVG
                     PGVYDIHSPRVPNEGEIDNTIEAILAKVPSKKVWINPDCGLKTRGIPETKESLIRLVE
                     AAKAAREKL"
     gene            14027..14893
                     /gene="metF"
                     /locus_tag="VQU30_001323"
     CDS             14027..14893
                     /gene="metF"
                     /locus_tag="VQU30_001323"
                     /EC_number="1.5.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000089969.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methylenetetrahydrofolate reductase [NAD(P)H]"
                     /protein_id="HET2447428.1"
                     /translation="MSRQTPSLSFEVFPPNPAVGNGNIISALQDMQELAPHFISVTAS
                     NNKFNIKETTVRLADFIQNDLAIPTIAHLPAIYLTKDKVAETIADLDKVGVQKILALR
                     GDIIPDVEPQKDFRYATDLIEFIKEQAPHFDIIGACYPEGHPDSPNQISDIQNLKKKV
                     DAGCSSLVTQLFFDNERFYDFQDKCILAGIDVPIHAGIMPILNRNQALRLLKTCENIH
                     LPRKFKAILDKYEHDPESLRAAGLAYAVDQIVDLVTQDVAGVHLYTMNNADTAKYIHQ
                     ATHALFNHQSLG"
     gene            15578..17791
                     /gene="pnp"
                     /locus_tag="VQU30_001324"
     CDS             15578..17791
                     /gene="pnp"
                     /locus_tag="VQU30_001324"
                     /EC_number="2.7.7.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001854499.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyribonucleotide nucleotidyltransferase"
                     /protein_id="HET2447429.1"
                     /translation="MAKQVFQTTFAGRELIVETGQVAKQANGSVVVRYGESTVLTAAV
                     MSKKMATGDFFPLQVNYEEKMYAAGKFPGGFMKREGRPSTDATLTARLIDRPIRPMFA
                     EGFRNEVQVINTVLSYDENASAPMAAMFGSSLALSISDIPFDGPIAGVQVGYVDDQII
                     INPSQEQAEQSLLELTVAGTKHAINMVESGAKELSEEIMLEALLKGHEAVKELIAFQE
                     EIVAAVGKEKAEVELLHVDAELQAEIIAAYNSDLQKAVQVEEKLAREAATQAVKDQVT
                     AVYEEKYADHEEFDRIMRDVAEILEQMEHAEVRRLITEDKVRPDGRKVDEIRPLDAVV
                     DFLPRVHGSGLFTRGQTQALSVLTLAPMGETQIIDGLDPEYKKRFMHHYNFPQYSVGE
                     TGRYGAPGRREIGHGALGERALAQVLPSLEEFPYAIRLVAEVLESNGSSSQASICAGT
                     LALMAGGVPIKAPVAGIAMGLISDGNNYTVLTDIQGLEDHFGDMDFKVAGTRDGITAL
                     QMDIKIQGITAEILTEALAQAKKARFEILDVIEATIPEVRLELAPTAPKIDTIKIDVD
                     KIKIVIGKGGETIDKIIAETGVKIDIDEEGNVSIYSSDQDAINRAKEIIAGLVREAKV
                     DEVYRAKVVRIEKFGAFVNLFDKTDALVHISEMAWTRTNRVEDLVEIGDEVDVKVIKI
                     DEKGRIDASMKALLPRPPKPEHDEKGEKSERPHRPRHHKDHKPKKEFTETPKDSE"
     gene            17807..18424
                     /gene="cysE"
                     /locus_tag="VQU30_001325"
     CDS             17807..18424
                     /gene="cysE"
                     /locus_tag="VQU30_001325"
                     /EC_number="2.3.1.30"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000539958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine O-acetyltransferase"
                     /protein_id="HET2447430.1"
                     /translation="MGWWRETIDIVKENDPAARTTLEVLLTYPGVKALAAHRLSHFIW
                     KHGFKLLARMHSQFWRFWTQIEIHPGAQIDSGVFIDHGSGLVIGETAIVEKGVLLYHG
                     VTLGGTGKDCGKRHPTVRKGALISAHAQVIGPVEIGENAKVGAAAVVVADVPSDVTVV
                     GIPAKIVRLHGKKDEPVIHEVEEKREYYVNKLEQAKDASHRSSGL"
     gene            18436..19320
                     /locus_tag="VQU30_001326"
     CDS             18436..19320
                     /locus_tag="VQU30_001326"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000613615.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HET2447431.1"
                     /translation="MIQVRNKLSQEELSEAKKVINCCQNYDGTYRDPYLSNMLNFDPN
                     MPAFFLYYEKGELVGLLTVYADDQDVEVTILVHPGHRRQGIARALFTSFERETASFPI
                     RSVTFQTERIFLENHPDFASNWGLIEDEETETWLGKDRRPYPLANVSHIEVLLADSSY
                     QDQISQLKFQAFSEEHESREVVDRYVAEALKDPESRLYILLKDGQVIGTCTVDLSTNT
                     NYFYGLAISEPERGKGYGSYLAKSLVNQLIEQNDKEFQIAVEDSNVGAKRLYEKIGFV
                     KQTQVVYLNEKGARDSEV"
     gene            19402..20745
                     /locus_tag="VQU30_001327"
     CDS             19402..20745
                     /locus_tag="VQU30_001327"
                     /EC_number="6.1.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002916477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine--tRNA ligase"
                     /protein_id="HET2447432.1"
                     /translation="MIKIYDTMSRDLREFVPIEDGKIKMYVCGPTVYNYIHVGNARST
                     VAFDTIRRYFEYRGYEVAYISNFTDVDDKIINRAREEGITPQEVADKYIAAFREDVTA
                     LGVKPATRHPRVVEFMADIIRFVEGLIEKGFAYESQGDVYFRVEKSHNYAKLANKTLE
                     DLELGASGRTDEETARKENPVDFALWKSSKPGEISWDSPWGPGRPGWHIECSVMSTEI
                     LGDTIDIHGGGADLEFPHHTNEIAQSEAKTGKAFANYWMHNGFVNIDNVKMSKSLGNF
                     ITVHDALKTLDGQVLRFFFATQHYRKPINFTEKAVRDAETNLKYLKNTYEQPFTGNVD
                     AQELQNFKDKFVAAMDEDFNAANGITVVFEMAKWINSGNYDASVKQALADMLEIFGIV
                     FVEEVLDAEIEDLIQKRQEARANRDFATADQIRDQLVTQGIKLLDTKDGVRWTRD"
     gene            20738..21124
                     /locus_tag="VQU30_001328"
     CDS             20738..21124
                     /locus_tag="VQU30_001328"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006148900.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Mini-ribonuclease 3"
                     /protein_id="HET2447433.1"
                     /translation="MIDVNLINGIALAFEGDAVYSMYIRRHLILKGMTKPNKLHQEAT
                     KYVSAKAQARLISLMLEEQILTEKEEEIYKRGRNTNSHTKAKNADVVTYRMSTGFEAV
                     MGYLHMTENLERLESLVSWCIQKVEG"
     gene            21128..22012
                     /locus_tag="VQU30_001329"
     CDS             21128..22012
                     /locus_tag="VQU30_001329"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844585.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PucR family transcriptional regulator"
                     /protein_id="HET2447434.1"
                     /translation="MRAKELQDWFPEARISDQPVEKEGYLTLPLASQQWILLEEAGLS
                     EREKQLVALLTQQEQARSLNPWYSYLVEGKGQAPQVFKKIQLVYCHLSYFQQENLASW
                     LDMMRTLFPNCQTVLQVGAQDYVFVLQQDKYTSVRDILSDMIEAVEYDFGLRLSIMLG
                     QVWSQTGHQALSDLIKAERDLFKTWWRQGHQGVHTFSQLYLWSMGERLVDLKPIKECL
                     HQMILDQDQIQEIILSLWENSAVLTKTAQQLYLHRNSLQYKIDKWEELTGLQLKELTD
                     LTLCYQLILGSLSTIVGL"
BASE COUNT         6765 a         3964 c         4861 g         6427 t
ORIGIN      
        1 accccaaaag ttagattttt tctgtctaac ttttggggtg tagttcacag ttgaagagcc
       61 agaaaattaa agtgtctttt actcaatcaa aaatagtaac gcctattctt ttggtgaata
      121 agactattgt ttggtatggt gcaatgccat tattagggaa ggtagatgag atgaccatat
      181 tacgtttgga atcagctagt atagtttctg aactagtggc aggtttacga tagagaaaat
      241 ttttaaaaat ttctatgtat gattttcatt tctttagtga gactgttgcc attatcacat
      301 tcgaatcaca caaaataaaa aaatttctac aagtacttga caaatagatt gaaatatcat
      361 aaaatgaaaa tggttacaga gttattaatt atttaagctt catgtcacca ttaaaaattg
      421 aaataaaagg atgttatcac taatacaagt gagcaggaac ctatttaatc acatcggaag
      481 aagtttcttg atgtttttaa gtaggttcct tttattttaa aagggaaatt ttatgatcat
      541 aaaacgaata ctaaaccaca atgccgtaat tgcgcaaagt aaaaaagata tcgatattct
      601 tctttttgga aggggcatag cttttggaag aaaaactgga gataaagtaa atccaattga
      661 tattgagaaa agtttttttc tcaaaaatag agataatatg acccgtttta cagagatgtt
      721 tattaacgtt cctttggagt tggtgtacat caccgaaaaa ataattaacc taggtaaaat
      781 aacattgggt aataattttg atgaaattat ctatattaat ttaacggatc atatttcttc
      841 gagcatagaa cgttataaag aagggattat tatttcgaat cccctacgct gggaaatatc
      901 gaaatattat aaagaagaat ttgaacttgg gaaaagggct ttacaaataa taaaaaaaga
      961 gttaggtatt gaacttccaa ttgacgaagc tgcattcata gcgctacatt ttgttaatgc
     1021 taatttagaa aataattttc aagagtcgta taaaatcact gaaataatta tgggaattga
     1081 gaaaatcatt caagatttct attgtactga gtttaaccaa gattctattg attattatag
     1141 attcataact catataaaat tatttgctca tcgcttggtt gaaaatacaa cttattgtga
     1201 cgatgatgat gaagacttgt tagcattaat gaaaaataaa tatcctagag aatatgaatg
     1261 tggtgaacag gtggcaatgt ttatacaaac tgagtacaat tatttgctga cttctagtga
     1321 attagtttat ttgatggctc atattcgtcg cttaacaaaa aatttagatt aatagaatag
     1381 gagaatacca tgagttataa agatacggta caaaaaatcc tcgatgtaat tggaggtgaa
     1441 aaaaatgtca atagagttac ccattgtgta acacgtttaa gattagaatt aaaagatgaa
     1501 aatttagtca atgatgatga tgtgaagaag ataccagatg taataggtat tatgaaaaag
     1561 aatggacaat atcaaattat acttggtaat gatgtagcta attattataa agaattcgtt
     1621 aaacttggca attttgaatc cgattcagtt gttcaagggc acaaagggaa tattttagaa
     1681 agaatcattg agtatatcgc tggttccatg actccaatca ttccagcaat gttaggggga
     1741 ggtatgttga aagtcttggt aatcatttta ccaatgcttg gtatattgca atcagattct
     1801 cagactattg cttttttgac attttttggg gatgctccat attatttctt accgctgtta
     1861 ttagcttatt ctgcatcaca aaaattaaaa gtaacatcta cattagctat gtctgtagca
     1921 ggtgtacttc tccatccaaa ttttgttcaa atggtgcaat cagggaatcc tcttagttta
     1981 tttggtgcac ctgtgacacc agctagttat ggttcatcag tcgttccaat tcttattatg
     2041 gtttggttga tgaaatatat tgaaaaaata attgctaaat taacaccagc tattactaag
     2101 agttttttgc aacctacgct agtattatta gtatcaagct gtattgcctt agttgtagtc
     2161 ggacctattg gagtaattgt tggtgaagga ttatcaaatc tagttgggca aatgtatggt
     2221 gtagctggat ggcttacatt agctattctt ggtgctatta tgccatttat tgttatgact
     2281 ggaatgcatt gggcttttgc acctattttt ttggcggcat ctattgctac tccagacgta
     2341 ttaattcttc cagcaatgtt agggtcaaac ttagctcaag gggctgcttc gatggctgtt
     2401 gcattaaaga gtaaaaataa taatacaaaa caaattgctt ttgcagcagg tttctcagcc
     2461 ttacttgcag ggattaccga acctgcatta tatggtgtga ctttaaaata taaaaaaccg
     2521 ctttatgcag ctatgattgg tggtggatta gcgggattat ttgcaggtct tactagtgtt
     2581 aaagcatatc tatttgctgt cccatctttg atagcgttgc ctcaatttat ttattctgat
     2641 gtgccatcaa atattgtaaa tgctttaatt gtggcggtca tttcggttgt tattaccttt
     2701 gtattagctt atatatttgg aatcgatgaa gaagagagtt ctagcaattt agaagttaaa
     2761 gctggagttt caaataaaaa aatgatattt tctcctatat caggagaaat cattccgtta
     2821 agcgatgtcc aggataaaac attttcagat aaattaattg gagacggagt agcgattatc
     2881 ccaagtgaag gtaaggttta tgcaccattt gatgggaaaa ttacaaatat ttttccgact
     2941 aagcacgcaa ttggattgaa gagtgatgag ggtgttgagt tactaattca tattggatta
     3001 gatactgttg agctaaaagg tcaaggtttt attagtcatg tagaagaagg agacagagtt
     3061 ttcaaaaatc agttgatttt tgaaatgaac ttgaatttaa tcaagactaa aggctacgaa
     3121 acagttacac cagtaattgt aacgaatacc aatgattttc tagatgtatt agtattacct
     3181 aataatcaga caatcgagca ttctaaggaa ttactggtaa tattataatg gaggaaagtt
     3241 atgaccattt ttccagatga ttttctttgg ggtggagcgg ttgcagctaa tcaagtagag
     3301 ggagcatata atgaagatgg taagggctta tcagttcagg atgtgttacc caaaggtgga
     3361 ttaggagaag caacagaaaa tcctacagaa gataacttaa aattgatagg tattgatttt
     3421 tatcataaat ataaggaaga tatatccttg ttttctgaaa tgggctttaa tgtttttcgt
     3481 acttctattg catggagtag aatttttcca aaaggagatg aggaagaacc taacgaagct
     3541 ggtttgaaat attatgatga attatttgat gaactacatg ctcacgggat agaaccactt
     3601 gtaactcttt cacactatga gactccatta tatttagcaa gaaaatatca tggatggatt
     3661 gataggagaa tgattcattt ttatgaaaaa tttgctcgaa cagttttaga aaggtataaa
     3721 gataaagtta aatattggct tacatttaac gaagtaaact ctgttttgga attaccgttt
     3781 actagtggag gaatagatat acctaaggag aatctttcga aacaagaatt atatcaagct
     3841 atacatcatg aattagtcgc ctcgagtttg gttacaaaaa ttgctcgtga gattaattca
     3901 gagtttaagg tggggtgtat ggtattagct atgccagctt atccaatgac tccaaatcca
     3961 aaagatgtat gggcgactca tgagtatgag aatctaaatt atctattttc agatgtgcat
     4021 gttagaggtt attatccgaa ttatgcaaaa agatatttta aggaaaatga cattaacata
     4081 gagtttgcag ctgaagatgc agagttatta aaaaattata ctgtagattt tttatccttt
     4141 agctattaca tgagtgtgac tcaatctgct attccaacac agtataattc aggagaaggg
     4201 aatattattg gtggtttagt aaatccttat ttagagtctt cagagtgggg atggcaaatt
     4261 gatccaattg gactacgtat aattttaaat agatattatg accgttatca aatcccatta
     4321 tttatagtag aaaatggatt aggtgctaaa gatcaactaa taaaagatga acttaataac
     4381 ttaaccgtcc aagatgatta tagaattcag tatatgaaag aacatttatt gcaagttgct
     4441 gaagctctac aggatggtgt tgaaattatg ggctatacgt cttggggatg tattgactgt
     4501 gtttctatgt ccactgcaca actttctaaa aggtacggtc tcatttatgt tgatcgaaat
     4561 gatgatggaa atggcacatt caatcgatat aagaaaatgt cctttacttg gtataaagga
     4621 gtgattgaat caaatggaga atccttattc aaatagtttg tttattgatg attagatatt
     4681 atcacggtta aggcaacatc tcattaaata taaaataaag aggtttggaa gacatcaaat
     4741 tctaaacctc tttattttat agggggatta attaatttaa ttttgttaca gagagccgat
     4801 tataaatagt taacttagga tagattggtt atatatagta gactgaatct aaaatagtac
     4861 gaaacaattg ctaaaacatt tatagaaatt aattttactt tcccaatcga tttgttttca
     4921 tcttatttca atccgctata aagttagata agaataagct aacaagcaga agtaagatag
     4981 gtcttgcaag aatggtaaaa atctgataaa ctaagtagta attgaatagg aatctgaaag
     5041 actagtagcc caagggaagt atatcaggga ggagagccgt gactgcaagc tctctatatg
     5101 aaagctgggt gaattcactt gcgcatggat ttagaaatga aggtctgact tgtcagatga
     5161 aaacggatgg taccgcgtgt caacgctccg agtggagttt ttggcatgtg gttttctttt
     5221 tatctacgag agactgatgg aggaaatatg tcaactattg aagaacaatt aaaagcgctt
     5281 cgcgaagaaa cgctggctag cttgaagcag attactgctg gaaatgaaaa agagatgcaa
     5341 gatttgcgtg tctctgtcct tggtaaaaag ggttcgctca ctgaaatcct caaagggatg
     5401 aaagatgttt ctgctgagat gcgtccaatc atcgggaaac acgtcaatga agctcgtgat
     5461 gtcttgactg ctgcttttga agaaacagct aagctcttgg aagaaaagaa agtcgcggct
     5521 caactggcta gcgagagtat cgatgtgacg cttccaggtc gtccagttgc gactggtcac
     5581 cgtcacgttt tgacacaaac cagtgaagaa atcgaagata tcttcatcgg tatgggttat
     5641 caagtcgtgg atggttttga agtggagcaa gactactata actttgaacg tatgaacctt
     5701 ccaaaagacc acccagctcg tgatatgcag gatactttct atatcactga agaaatcttg
     5761 ctccgtaccc acacgtctcc agttcaggcg cgtgctatgg atgcccatga tttttctaaa
     5821 ggtcctttga agatgatctc gccagggcgt gtcttccgtc gcgatacgga cgatgcgacc
     5881 cacagtcacc aattccacca aatcgaaggc ttggtagttg ggaaaaatat ctctatggct
     5941 gatcttcaag gaacgcttca gttgattgtc caaaaaatgt ttggtgaaga gcgtcaaatt
     6001 cgtttgcgtc catcttactt cccattcaca gagccatctg ttgaggtgga tgtttcttgc
     6061 ttcaagtgtg gtggagaagg ctgtaatgta tgtaagaaaa caggttggat cgaaattatg
     6121 ggggccggta tggttcaccc acgtgtcctt gaaatgagtg gtatcgatgc gactgtatac
     6181 tctggctttg cctttggtct tggacaagag cgtgtagcta tgctccgtta tggaatcaac
     6241 gatatccgtg gattctacca aggagatgtc cgcttctcag aacagtttaa ataatgatta
     6301 gaaaagtaga aatggcagat gttgaggtgt tggctaaaat tgccaaacaa gcctttcgtg
     6361 aaacctttgc gtatgataat acggaagagc agttacagga atactttgaa gaggcttata
     6421 gtctgaaaac tttgtcaact gagttgggaa atcctgactc tgaaacctat ttcattatgc
     6481 atgaggagga gatagctggt tttctcaaag tcaactgggg aagtgctcaa actgagagag
     6541 aattagagga cgcttttgaa attcaacgcc tctatgtgct acaaaaattc caaggatttg
     6601 gactaggtaa gcaactgttt gaattcgcac ttgaacttgc tacaaaaaat agtttttctt
     6661 gggcttggct aggtgtttgg gagcataata caaaagctca agcgttttat aaccgatatg
     6721 gttttgaaaa atttagccaa catcatttta tggttggtca aaaagtagat acggattggt
     6781 tactgagaaa gaaattaagg taagaagaga attcttctat tgaaatgata ggaaaggaaa
     6841 agaaccagtg tggcaatggt cattctggag aactaaatta tgcttgtatc ttataaatgg
     6901 ttaaaagaat tggtgggcat tgatgtgcca tcacaggagt tggctgaaaa aatgtcaacc
     6961 acagggatcg aggtcgaagg tgtcgaatca ccagctgccg gtctttcaaa aattgtcgtc
     7021 ggtgagatct tgtcttgcga agatgtgcca gaaactcacc ttcatgtttg tcaggttaac
     7081 gttggcgaag aagaagagcg tcagatcgtt tgtggtgccc caaatgtgcg tgcaggcatc
     7141 aaggttatgg tggctcttcc gggagctcgt atcgctgaca attacaaaat caaaaaagga
     7201 aaaatccgtg gcttagagtc acttggaatg atctgttcac ttggtgaatt gggtatttct
     7261 gactcagttg tacctaagaa attcgcagat ggtattcaaa ttttgccaga aaatgccgtt
     7321 ccaggtgagg aagtcttttc atatctagac ttggatgatg aaatcatcga actttctatc
     7381 acaccaaacc gtgcagatgc cctttctatg cgtggagtgg ctcacgaagt ggcagccata
     7441 tatgacaagg cagtcaactt taaagaattt actttgacag aaacaaatga agctgcgaca
     7501 gatgcccttt ctgtgggcat tgagacagac aaggcgcctt actatgcagc tcgtatcttg
     7561 gacaatgtga ctatcgcacc aagtccacaa tggttgcaaa accttctcat gaacgaaggc
     7621 atccgtccca tcaataacgt tgtagacgtg acaaactaca tcctgctcta ctttggtcaa
     7681 cctatgcatg cttttgactt ggacacattt gaagggactg acatccgtgt gcgtgaagcg
     7741 cgtgctggtg aaaaattggt gaccttggac ggtgaagaac gtgacttgga cgtgaatgac
     7801 ctagtcatca ctgttgcaga caagccagta gcccttgcag gtgtcatggg tggtcaagca
     7861 acagaaatct ctgaaaaatc tagtcatgtt gtccttgaag ctgctgtttt caatggcaaa
     7921 tctatccgta agacaagtgg tcgcctgaac cttcgttctg agtcatcttc tcgctttgaa
     7981 aaaggaatta atgtggcaac agttaatgaa gcccttgatg cggcagctag cctgattgcg
     8041 gaacttgcag gtgcgacggt gcgtaagggt atcgtttcag cgggtgagct tgatacttca
     8101 gatgtagaag tttcttcaac tcttgctgat gttaaccgtg tcctcggaac tgagctgtct
     8161 tatgctgatg tcgaagacgt cttccgtcgt cttggctttg gtctttctgg aaatgcagac
     8221 agctttacag tcagcgtacc acgtcgtcgt tgggatatca caatcgaagc tgatctcttt
     8281 gaagaaatcg ctcgtatcta tggatatgac cgcttgccaa ccagccttcc aaaagacgat
     8341 ggtacagctg gtgaattgac tgtgacacaa aaactcagcc gtcaagttcg taccattgct
     8401 gaaggagcag gtttgacaga aatcatcacc tatgttctaa caactcctga aaaagcagtt
     8461 gagtttacgg ctcaaccaag taaccttacg gaactcatgt ggccaatgac tgtggatcgt
     8521 tcagtcctcc gtcaaaatat gatttcaggt atccttgata ccgttgccta caacgtggct
     8581 cgtaagaata aaaacttggc cctttacgag attggaaaag tctttgaaca aacaggtaat
     8641 ccaaaagaag aacttccaaa tgaaatcaac agttttgcct ttgccttgac aggcttggtt
     8701 gctgaaaaag atttccaaac agcagcagtt ccagttgatt tcttctatgc taaaggaatc
     8761 ctagaagcgc tctttactcg cttgggacta gaagtgacct atacagcaac agctgagatt
     8821 gccagccttc acccaggacg tacagcagtc atttcactcg gtgaccaagt tcttggtttt
     8881 cttggccaag tgcatccagt cactgctaag gcttacgata ttccagaaac gtatgtggct
     8941 gagctcaacc tttcagtcat cgaagctgcc cttcaacctg ctgctccatt tgtggaaatc
     9001 acgaaattcc cagcagtcag ccgtgacgtt gcccttctcc tcaaggcagc agtaactcac
     9061 caagaagtta tagatgctat ccaagctgcc ggcgtgaaac gtttgacaga tatcaaactc
     9121 tttgacgttt tctcaggtga gaaattggga cttggtatga agtcaatggc ttatagcttg
     9181 accttccaaa atccagaaga cagcttaacg gacgaagaag tcgcacgcta catggaaaaa
     9241 atccaagcat cgcttgaaaa aaaagtgaac gcagaagtgc gttaaacgat agtaggatac
     9301 aaattccccc tctagtttat gaacactaga ggggtgattt tatataatac tcaatgaaaa
     9361 tcaaaaagca aactaggaag ctagccgtaa gctgtacttg agtactgtaa ggcgaggctg
     9421 acgtggtttg aagagattgt cgaagagtat aaaataatta aaatgtgatt tctgtaaaaa
     9481 tacatctatg atcagagttt tgaaaactta caatgtctaa atctttaaca tagtagtggt
     9541 ttttaggcaa taaaatatga tctattgttg cattaaaaag ttttggactt tggctattcc
     9601 aagttcctct ttcaaaaggt ggtagtacat ttaatgcgtc cctatgagag cttatttttg
     9661 caagtgctcc atgacgcata gttgcattaa aatcatctgc aataatagcc tttggatatt
     9721 ttgaagccaa ttgattatga atgatgttta agtcttgctt ccagatttcc attaaacctg
     9781 gcagaggagg agcagtatgc aaggcaatga tatctggtat attttgtttt ctcgaatgta
     9841 atacaattgt cccgaaccgt gttgtatgaa aagttttagc ttctgtatag aaaccataac
     9901 ttttcttgac aatcacagtc acaggagcta ttccactatt ggtaggtgga gaagtgaaaa
     9961 tatcatagtt ggccatagaa agtccaactt gatgaaacaa tagtttgatt ctctggtttt
    10021 cttgctcacc tctgatattg gtagctagtt cagggaatat agccatatcg gcgtcaaaat
    10081 ggctaaaaat tcgctcaata tgttgtgctt ctatttgatt agcgacgttc caagttacta
    10141 attttaaggt tttagtctta tttgatgcag aagaaagggt tttatctgtt ccgaataata
    10201 gtaatatgag cgatagtaag agcaaaatgc cagagtaaaa ccgtatttgt ttatttttct
    10261 tgtaaaaaga tagggaaaaa aatacgaaac ttaaaatagc agccatagtt gcagtagcta
    10321 aggggaaggc ataaatctgt gccaagatag gtctggtaga tagccaaata ttaagattag
    10381 aagatggaaa aaaagaataa gttatgatag ggataacaaa gagaatgacc gaaagggcag
    10441 agagaaatgt tttaatcatt gtgtgagtac ctcaatttgc aatggttgct cggagctaat
    10501 gtgactttgt gactttactt gattgatatt ctttttcttg tcttcctcat agattaagta
    10561 caacccaagt aaaaaaagtc caatttaaga ttgaaatgat taaaaggcac agaaatgcaa
    10621 gacaattata ctacaaaagg caaacatttg acaatcgata gccgtcgctt aatcgaaaga
    10681 tggaaaaaag aagggaaatc aaatagagaa attgcctctc tgcttggaaa agttcctcaa
    10741 actatccaca ctgaaatcaa gcgtgggaca gtccgacaat gtcttggaaa agggcgcttc
    10801 aaagaggttt attctgccga ctatgctcaa cagtcttatg aaaacaatcg caagcgctcg
    10861 gtcaagaaat caagcttgac caaggaacta aaggaaaaga ttctccacta tcataaccaa
    10921 aaattttcgc ttgaaatgat ggtgatggct aaaggggtta acgtgggaat ttcaaccatt
    10981 tactattgga ttcatcgtgg aaaattgggg ttaagcaagc aggatctgct ttaccctaga
    11041 aaaggaaaag cgcttaagaa acaggctagc accaacttta aacctgctgg tcaatctatc
    11101 gaatcataat tcgctcattc ttttaaaaat acatagacgt aaaagaaaga gggttaagtg
    11161 atgaagaata gtgctattgg gagtaattgg aaggatgtcc atctgagctc tttagcaagg
    11221 aggaaatcct tgaaagtgat atgcgagtgg ctatcatgag cgagttgatt gaggctaggt
    11281 atgaacaagg aatcagtcag aaaaagctgg aagaagtcag tggagtgagt caacctgtca
    11341 tagctaggat ggaaacagga gagagcagtc ttcagttgga tacggtctta aaagttctaa
    11401 ccagtctagg aaagacacta gcagtcgttc cacttgaaca ggggaaaagt tgactagaat
    11461 cagttatagt cttttctaat aacaggtcat agtcacttat aagaattact aataacatgt
    11521 tttagtattc taattggaat atagctgtaa agtaagaatt acaaaggatt tgagacgttt
    11581 gcttcaagtc tttttctttt gtccgaaaca gatatatagt ttcaaactat atcaaaccct
    11641 aattttttac aattatacag acgctttctt ttctgttaag atagtttcaa caacaaattt
    11701 tggaggacac atcatgtcaa ctacaatcat cggtttccct cgtttgggcg aattccgtga
    11761 attaaaattt acaactgaaa aatactttag aaaagaaatc tcagaagaag aacttttagc
    11821 agcagcaaaa gacttgcgtg ctaaacactg gaacattgtc aaagaaaaag gcatcactga
    11881 aattccatca aatgactttt ctcactatga taacttccta gatgcggctt tccttttcaa
    11941 cgtggtgcct gcatccgttc aaaacttgga cttgtctgac cttgagcgct acttcgcttt
    12001 gggacgtggt taccagggag aaaaagggga cgttcgcgcc cttccaatga agaaatggtt
    12061 caacactaac taccactaca tcgttcctaa atttgaaaaa gacactcaag taaaattggc
    12121 tggtcacaag attttcgatg agttccaaga agccaaagaa cttggattga acactcgtcc
    12181 tgttcttgta ggtcccttca ctttccttca attgtcagac tttgaagaag gcgtgaaagc
    12241 agacgacttc gtagatagct tagtggctgc ttaccaagaa gtttttgcta aattggctga
    12301 acttggtgcg actcgcatcc aattggatga agcggctctt gtaaaagact tgacagctga
    12361 agaaaaagct ctcttcttga acctttacaa caaactcttg gctgacaaaa aaggtcttga
    12421 agtcttgctt caaacttatt tcggtgatgt tcgtgacgta tacgctgacc ttgtaaactt
    12481 accagtagat gctatcggtc ttgactttgt tgaaggtaag aaaactcttg aactcgttaa
    12541 aggtggcttc ccagctgaca agactctcta tgtaggtatt gtcaatggta aaaacatctg
    12601 gcgcaacaac tacgaaaaga gcttggctgt tcttgagcaa attccagctg aaaacatcgt
    12661 tttgacaagc tcttgctcac ttcttcatgt gccatttaca actgctaatg aagaatttga
    12721 accagcactc ttgaaccact ttgcctttgc agttgaaaaa ttggatgaaa tccgtgactt
    12781 ggatgctatc cgcaatggtc aaggttcaga agctcttgca gccaacaaag aactctttgc
    12841 gactgagcgt gttggtgaaa atgctgaact tcgtgcgcgt atcgctggct tgacagacgc
    12901 agactacact cgtttgccag cctttgcaga acgtgaagct atccaagaag aagctttcaa
    12961 acttccagct cttccaacaa caacgattgg ttcattccct caaacaaaag aagttcgtgc
    13021 caaacgtttg gcttaccgta aaggtgaatt gtctcaaaaa gagtacgatg ctttccttgc
    13081 tgaaacgatt gacgaatgga tcaagtggca agaagatatt gactttgatg tccttgttca
    13141 cggtgaattt gagcgtaatg acatggttga gtacttcggt caaaacttgt caggatacct
    13201 cttctctaaa aatggatggg tacaatcata cggtatgcgt ggggtaaaac caccaatcat
    13261 ctggggtgat gtcactcgtc ttaaccctat cactgttaaa tggtctagct atgcacaaag
    13321 tcgtacaaac aaacctgtta aaggtatgtt gactggacct gttaccatcc ttaactggtc
    13381 attcccacgt gaagacatct ctatcaagga ttctactctt caaatcgccc ttgctatcaa
    13441 ggatgaagtg cttgaccttg aagctgctgg tgtgaaaatc atccaaattg atgaggctgc
    13501 tcttcgtgaa aaattgccac tccgtcgtag tgactggtac gaagattacc ttgactgggc
    13561 aattcctgcc ttccgcttgg tacactcaac agtagcgtca gacacacaaa tccacactca
    13621 catgtgttac tcagaattta cagatatcat cccagctatc gataacatgg atgcagacgt
    13681 tatttccttt gaagccagcc gttcaaacct tgaaatcttg gacgaactca aagcgaaaaa
    13741 cttccaaaca gaagtgggac ctggggttta cgatatccac tcacctcgtg taccaaatga
    13801 aggcgaaatc gacaacacaa tcgaagccat ccttgctaaa gtgccaagca agaaagtttg
    13861 gatcaaccct gactgtggtt tgaaaacacg tggtatccca gaaacaaaag aaagcttgat
    13921 ccgccttgtt gaagcagcta aagctgcgcg tgagaaattg taagattgga tttctctcca
    13981 tacagtggtt gttcaaaaag aaatcaacta gaaaaggtta ttacatatgt cacgccaaac
    14041 accgtcactc tcatttgaag tgttccctcc aaacccagcc gtgggtaatg gtaacattat
    14101 ttcagccttg caggatatgc aggagttggc tccccatttt atcagtgtaa ctgccagcaa
    14161 taataaattt aatatcaagg aaacgacggt tcgtttggct gactttatcc aaaatgactt
    14221 ggcgattccg accattgccc acttgccagc tatttatcta actaaggaca aggttgctga
    14281 aactattgct gacttggaca aagttggggt tcagaaaatc ttggctcttc gtggggatat
    14341 tattccagac gtagaaccac aaaaggattt ccgctatgca accgacttga ttgagtttat
    14401 caaggaacaa gcccctcact ttgatattat tggagcttgc tatccagaag ggcatccaga
    14461 ttcgccaaat cagatttcag atattcaaaa tcttaagaag aaagtggatg caggctgttc
    14521 gagcctcgta actcagctct tctttgacaa tgagcgcttc tatgattttc aggacaagtg
    14581 tatcttggct gggattgatg ttcctattca tgcaggaatt atgccaattc tgaatcgaaa
    14641 tcaggctctc cgactcttga agacttgtga gaatatccat cttccacgca aatttaaagc
    14701 catcttagac aagtatgagc atgaccctga gtcgctcaga gcagcaggac ttgcctatgc
    14761 agtggaccaa atcgtggact tggtaactca ggatgttgcc ggtgtgcatc tctatacgat
    14821 gaataatgct gatacagcaa aatacatcca tcaagcaacc catgccttgt ttaatcacca
    14881 gtctctagga taataaaagc aaaccattct tctcaggtga ggggaatggt tcctttttaa
    14941 tggtaaagac ctcacttttt aagaaaaata tgataaaata gattctgtac gtacttgata
    15001 caaagatgaa ggtattaaat aatacaatgc atttaaactg taagatttaa cgacacgagt
    15061 gagtcaaatc gatgttattt gacgaaagag ttagtaaagc atttagctaa tcgcccgata
    15121 gcgattagcg tgaaaggttt agatacttta atattaaacc tttctaatga tgtatcttga
    15181 aaactgaaca cgcctacaac tctgtggaaa aagataaatc tgcctaggag cagtcgctcc
    15241 gtcgttcgat ttcctatctt cctttgagtt gcttgacggc ttggtatctt gatgacttga
    15301 attttggtct catttcttag gaaaaaagat aagcttccta gcactcgtcg agtgcgacgt
    15361 caccttccta tttttctaca gaaatgttcg gcaagccgaa ccgtccaaaa tatcttgtgt
    15421 aattgaacac ggccgaaaag ctgtgtaaaa aagataaact gtcttgtctt catcgaagac
    15481 ttcgtcagtt tcctattttt actttgcttt tgacgtcctt ggtatcttga tctttgtagg
    15541 caaggcgtat aatttcatca atccaaaggg gattaaaatg gcaaaacaag tgtttcaaac
    15601 gacttttgcg ggtcgtgagt taattgtaga gactggtcag gttgctaagc aagcaaatgg
    15661 ctctgttgtc gtacgttacg gtgagtcaac tgtcttgact gctgccgtta tgtctaagaa
    15721 aatggcaact ggggattttt tcccactcca agtcaactac gaagaaaaaa tgtatgcggc
    15781 tgggaagttt cctggtggct ttatgaaacg tgaaggacgt ccttcaacag atgcgacctt
    15841 gacagcgcgt ttgattgacc gtccgattcg tcctatgttt gcggaaggtt tccgtaatga
    15901 agtccaagtc atcaatacag tgctttctta tgatgaaaat gcatctgcac caatggctgc
    15961 tatgtttggt tcatctttgg cactgtctat ttcagatatt ccatttgacg gaccaattgc
    16021 tggggtacaa gtgggatatg tagatgacca aatcatcatc aacccaagtc aagaacaagc
    16081 agagcaatct cttcttgaat tgacagtagc tggaactaag cacgctatca acatggtaga
    16141 gtctggtgcc aaagaattgt cagaagaaat catgttggaa gcgcttctta aagggcacga
    16201 agctgtcaaa gaattgattg ccttccaaga agaaatcgtt gctgctgtcg gtaaagaaaa
    16261 agcagaagtg gaattgcttc acgtggatgc tgaattgcaa gctgaaatca ttgcagccta
    16321 caacagtgac ctccaaaagg cagttcaagt agaagagaaa ttggcccgtg aagctgcaac
    16381 tcaagcagtg aaagaccaag tgactgccgt ttacgaagaa aaatatgcgg accacgaaga
    16441 atttgaccgt attatgcgtg atgtggctga aatcttggaa caaatggaac acgcagaagt
    16501 gcgacgttta attacagaag acaaggtgcg tcctgatggt cgtaaggtcg atgaaatccg
    16561 tcctttggat gcggttgttg acttccttcc tcgtgtacat ggttcaggtc tctttactcg
    16621 tgggcaaact caagctcttt cagtcttgac cttggctccg atgggagaaa ctcaaatcat
    16681 tgatggtttg gatccagagt acaagaaacg ctttatgcac cactataact tccctcaata
    16741 ttctgtaggg gaaacaggtc gttacggtgc gccaggtcgt cgtgaaatcg gtcacggtgc
    16801 ccttggtgag cgtgctcttg ctcaagtctt gccaagcttg gaagaattcc catacgctat
    16861 ccgtctagta gcagaagttt tggaatcaaa cggttcttca tctcaagctt ctatctgtgc
    16921 gggaactctt gcccttatgg ctggtggtgt gccaatcaag gcgccagtag ctggtattgc
    16981 tatgggactt atctcagatg gaaataacta cacagtattg acagatatcc aaggtttgga
    17041 agatcacttt ggagatatgg acttcaaggt tgcaggtact cgtgatggga ttacagccct
    17101 tcaaatggat atcaagattc aagggattac tgcagaaatc ttgacggagg ctcttgctca
    17161 agccaagaaa gcgcgttttg aaatccttga tgtcattgaa gcaaccattc cagaagttcg
    17221 tctagaattg gctccaactg ctccgaaaat tgatacgatc aagattgatg tggacaagat
    17281 taagattgtc atcggtaagg gtggagaaac catcgacaag attatcgctg aaacaggtgt
    17341 taagattgat atagacgaag aaggaaatgt gtctatctac tctagtgacc aagatgctat
    17401 taaccgtgcc aaagaaatta ttgctggttt ggttcgtgaa gccaaagtgg atgaagttta
    17461 ccgtgctaaa gtcgttcgta tcgagaaatt tggtgccttt gttaacctct ttgataagac
    17521 agatgccctt gttcatatct ctgagatggc ttggactcgt accaatcgtg tagaggattt
    17581 ggtagaaatc ggggatgaag ttgatgttaa ggttatcaag attgatgaaa aaggccgtat
    17641 cgatgcctct atgaaggctc ttctacctcg tccgccaaaa cctgagcatg atgaaaaagg
    17701 tgaaaagtct gagcgtcctc accgcccacg tcatcacaag gatcacaaac ctaagaaaga
    17761 atttacagaa acaccaaaag attcagaata agaaaaggag aaatgtatgg ggtggtggcg
    17821 cgaaaccatt gatatcgtaa aagaaaatga tccagcggcc cgcaccactt tggaggtttt
    17881 gctgacttat ccaggtgtca aggccttggc ggcccaccgt ctctcgcatt ttatctggaa
    17941 gcacggcttc aaactcttag ctcgtatgca cagtcagttt tggcgctttt ggactcagat
    18001 tgagattcat ccaggagccc agattgattc aggtgtcttt attgaccatg gttctggtct
    18061 ggtgattgga gagacagcga ttgttgaaaa aggcgttctt ctctatcacg gagtgactct
    18121 tgggggaaca gggaaagact gtggcaaacg ccatccgact gtacgaaagg gagccctcat
    18181 atcagcccat gcccaagtta tcggacctgt ggaaattggt gaaaatgcca aggtcggtgc
    18241 tgcagcagtt gtcgtagcag atgtacctag tgatgtgacg gttgtcggta ttccggccaa
    18301 gattgtccgt cttcatggta agaaagatga gcctgtcatt cacgaagtcg aagaaaaacg
    18361 agagtattat gtcaataaac tcgagcaggc taaagatgcc agtcacagat cgtctggttt
    18421 gtagaggata cctatatgat tcaagtaaga aacaagttaa gccaagagga gctatctgag
    18481 gcgaaaaaag taattaactg ttgccaaaac tatgacggta cctatcgcga tccctatctc
    18541 tctaacatgc ttaattttga cccaaacatg cccgcctttt tcctttatta tgaaaaaggc
    18601 gaacttgttg gtttattaac tgtctatgca gatgaccaag atgtagaagt gacgatactg
    18661 gttcatccag gtcatcgccg tcaggggatt gcgcgtgcat tgtttactag ttttgagaga
    18721 gaaacagctt ctttccccat tcgatcagtc acttttcaga cagaacgtat ttttttagag
    18781 aatcatcctg actttgccag taactgggga ctaatcgagg atgaagagac agaaacttgg
    18841 ttaggtaagg atagaagacc ttatccgtta gcaaatgttt cccatattga agttttgtta
    18901 gcagatagtt cgtatcagga tcaaattagt caattaaaat ttcaggcatt ttcagaggaa
    18961 catgaatcga gagaagttgt ggatagatat gtcgctgaag ctctgaagga tccagaaagc
    19021 cgactatata ttttgttaaa agacggtcag gttattggga cttgcacggt agatttatcg
    19081 actaatacga attacttcta cggtttagca atatcggaac ctgaacgtgg gaaaggctat
    19141 ggaagctact tagcaaaatc cctcgtcaac caactaattg agcaaaatga caaggaattt
    19201 cagattgcag tggaagatag caatgtaggt gccaaacgtt tgtatgaaaa aattggcttt
    19261 gtcaaacaga ctcaggtggt ttatctgaat gagaaaggag caagggattc cgaagtgtag
    19321 agatattcgg actgaaattt acttgaactt ttagtgatga aactaattgt tcttggattt
    19381 cagctttctt gattatgatt tatgattaaa atctatgaca ccatgtctcg tgatttgcga
    19441 gaatttgtcc cgattgagga cggcaagatc aagatgtatg tttgtgggcc aacggtgtac
    19501 aactatattc atgtagggaa tgctcgttca acggtagctt ttgataccat tcgtcgctat
    19561 tttgagtatc gtgggtacga ggttgcctat atttccaatt ttacggatgt ggatgataag
    19621 attatcaacc gtgccaggga agaaggcatc acgcctcagg aggttgcgga taagtacatc
    19681 gctgcctttc gtgaggatgt gacggccttg ggcgtgaaac ctgcgactcg ccatccgcgt
    19741 gtagtggagt ttatggcaga catcatccgt tttgtggaag gcttgatcga gaaaggcttt
    19801 gcctatgaga gtcaagggga tgtctatttc cgtgtagaaa aatcccacaa ctatgctaaa
    19861 ttggctaata aaaccttgga agatttggag ctaggtgctt caggtcgtac cgatgaagaa
    19921 acggctcgta aggaaaatcc tgtagacttt gctctatgga aatcttccaa accaggtgag
    19981 atttcttggg atagtccttg gggacctgga cgtccgggtt ggcatattga gtgttcagtc
    20041 atgtcgacag agattttagg tgataccatt gatattcacg gtggtggagc tgacctagag
    20101 tttccacacc acaccaatga aattgcccaa tctgaagcta aaacaggcaa ggcttttgct
    20161 aactactgga tgcacaatgg ctttgtcaat atcgacaatg tcaaaatgtc taagtccttg
    20221 ggtaacttca ttacggtaca cgatgccctt aaaactcttg atgggcaagt acttcgtttc
    20281 ttctttgcga cccagcacta ccgtaagcct atcaacttca cggaaaaggc agttcgcgat
    20341 gccgagacca atctcaagta tctgaagaat acttacgaac aaccatttac aggaaacgtg
    20401 gatgcccaag agttacaaaa ctttaaagat aagtttgtag cagctatgga tgaagatttt
    20461 aatgctgcca acggtatcac agttgtcttt gaaatggcca aatggatcaa ctcagggaac
    20521 tatgatgcaa gtgtcaagca agctcttgca gatatgttag aaatttttgg aattgtcttt
    20581 gttgaggaag ttttggatgc agagattgaa gacttgattc aaaaacgcca agaggcgcgt
    20641 gccaatcgtg actttgcgac agcagaccaa atccgtgacc aattggttac tcaaggaatt
    20701 aagctccttg ataccaagga tggagtgagg tggacacgtg attgatgtca atctcattaa
    20761 cgggattgcg ctagcctttg agggagatgc ggtgtattct atgtatattc gccgccacct
    20821 catcctcaaa ggtatgacca agcccaataa actccaccaa gaggcgacca agtacgtgtc
    20881 agccaaggct caagctcgcc tgatttctct catgttggag gagcagatcc taacggaaaa
    20941 agaagaagaa atctacaaac gtggccgcaa taccaatagt cacacaaagg ctaaaaatgc
    21001 agatgtcgtg acttatcgta tgtccacggg atttgaagca gttatgggct atctccatat
    21061 gactgagaat ctggaacgtc ttgagagttt ggtttcatgg tgcatccaaa aagtggaggg
    21121 ctagaacatg agggcaaaag aactacaaga ctggtttcct gaggctcgga tttcagacca
    21181 accagtagag aaagagggct atctcacgct tcctttagct tctcagcagt ggattttgct
    21241 ggaggaagct gggctcagcg agcgtgaaaa gcagttggtt gcccttttga cccagcagga
    21301 gcaggctcgt tcgctaaacc cttggtattc ctatctggtt gaaggcaagg gacaggcacc
    21361 gcaagttttt aaaaagattc agttggttta ttgccatctt tcttattttc agcaggaaaa
    21421 tctggcttct tggctagata tgatgcggac tctttttccg aattgtcaga cagtgttaca
    21481 ggtcggagct caggattatg ttttcgtgct tcaacaagac aaatacactt ctgtaagaga
    21541 tattttaagt gatatgattg aagcagttga gtatgacttt ggacttcgtc tttctatcat
    21601 gttgggtcag gtttggtctc agacaggaca tcaagcccta tcagacttaa tcaaagctga
    21661 gcgggatttg ttcaagacat ggtggcgtca gggtcaccaa ggtgttcata ctttttctca
    21721 gctctatctt tggagtatgg gagaaagact cgtggacttg aagccaatta aagaatgtct
    21781 acaccagatg attttggatc aagatcagat tcaggaaatc attctctctc tttgggaaaa
    21841 tagtgctgtt ctcactaaaa cagcccagca actctatctg caccgcaatt ctctccaata
    21901 caagattgat aaatgggaag agttgacagg gcttcagttg aaagagttga ccgacctgac
    21961 cttgtgttat caattgattt taggttcttt gtcaactata gttggtttgt aaagaag
//
LOCUS       DAVBBO010000035        21537 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ST1
            SAMEA2066453-rid20184263.denovo.035, whole genome shotgun sequence.
ACCESSION   DAVBBO010000035 DAVBBO010000000
VERSION     DAVBBO010000035.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2066453
            Sequence Read Archive: ERR351777
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 21537)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 21537)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980402.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980402.1
            Genome Coverage       :: 176x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:17:33
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,141
            CDSs (total)                      :: 2,104
            Genes (coding)                    :: 1,953
            CDSs (with protein)               :: 1,953
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 16S)
            partial rRNAs                     :: 1 (23S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 151
            CDSs (without protein)            :: 151
            Pseudo Genes (ambiguous residues) :: 0 of 151
            Pseudo Genes (frameshifted)       :: 73 of 151
            Pseudo Genes (incomplete)         :: 76 of 151
            Pseudo Genes (internal stop)      :: 40 of 151
            Pseudo Genes (multiple problems)  :: 32 of 151
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..21537
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2066453-rid20184263.denovo.035"
                     /strain="ST1"
                     /db_xref="taxon:1313"
     gene            <1..128
                     /locus_tag="VQU30_001330"
     CDS             <1..128
                     /locus_tag="VQU30_001330"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611512.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="IS3 family transposase"
                     /protein_id="HET2447435.1"
                     /translation="FRSLENLEQAIVDYIDYYNNKRIKVKLKELSPVQYRTKSFG"
     gene            complement(176..2719)
                     /locus_tag="VQU30_001331"
     CDS             complement(176..2719)
                     /locus_tag="VQU30_001331"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001861768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YfhO family protein"
                     /protein_id="HET2447436.1"
                     /translation="MKSFLKTYRTYFISFIIPVVIMSGVYLSQGIYWNSDNSPLLGDG
                     FHQYVIFDVALRNILHGNSSLFYTFTSGLGLNFYALSSYYLGSFLAPLVYFFDLTNMP
                     DAVYLTTLLKFGLIGLSTFFSLNKLFQSIPQTLKLALSTSYALMSFTVSQLEIKTWLD
                     VFILIPLIITGLHLLITEKKLLLYFTSLSILFIQNYYFGYMTVLFLIFWYLCQISWDF
                     KTRKSSVLDFIVISFLAGMASLIMTLPTLFDLQTHGEKLTEVTKFQTESSWYLDLFAK
                     QFIGSFDTTKYGAIPMIFVGLFPFILTILFFTLKSIKFHVKLIYVIFFAFLIASFYIE
                     ALDLFWQGMHTPNMFLHRYAWIFSTLLIYTAAEVLKRLKELKVWNFLVSLFLVVAGFL
                     ATIYLKSHYSFLTDLNILLTLEFLVVYSLLLLAVIKKFISVNLFAILISLFILVEMSL
                     NASSQMDGIAKEWGFASRSAYSRDIPAMESFSTYIGNQFTRTEKLQTQTGNDSMKFNY
                     NGISQFSSVRNRSSSSTLDKLGFKSSGTNLNLRYANNSILADSLFGIQYNISDSPIDK
                     YGFKDIYQKDNLTLYENQYSLPIAVASQSVYNDVKFNEHTLDNQASFLNQLANVNFDY
                     FSPIPYEKTENTNDLISVTSSSNEDAAIQYQIEVPENSQVYLSFINLHFSNDKQKKVD
                     ILVNGEKKTFTTDNVFSFFNLGYTKEKKTFNINVSFPGNSQVSFESPTFYRLDTKTFT
                     EAIQKIKEQPVTVSTSKNKVFATYDVQQDTSIFFTIPYDKGWSAYQDGKKIEIKQAQT
                     GFMKVDIPKGKGTITLSFIPNGFITGAICSFTSLLLFGIYNHRRKSSKA"
     gene            complement(2781..4403)
                     /locus_tag="VQU30_001332"
     CDS             complement(2781..4403)
                     /locus_tag="VQU30_001332"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015511338.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HET2447437.1"
                     /translation="MLTVSDVSLRFSDRKLFDDVNIKFTEGNTYGLIGANGAGKSTFL
                     KILAGDIEPTTGHISLGPDERLSVLRQNHFDYEDERAIDVVIMGNEKLYSIMKEKDAI
                     YMKEDFSDEDGVRAAELEGEFAELGGWEAESEASQLLQNLNIPEELHYQNMSELANGE
                     KVKVLLAKALFGKPDVLLLDEPTNGLDIQSITWLEDFLIDFDNTVIVVSHDRHFLNKV
                     CTHMADLDFGKIKLYVGNYDFWKESSELAAKLLADRNAKAEEKIKQLQEFVARFSANA
                     SKSRQATSRKKMLDKIELEEIVPSSRKYPFINFKAEREIGNDLLTVENLTVKIDGETI
                     LDNISFILRPDDKTALIGQNDIQTTALIRAIMGDIDYEGTVKWGVTTSQSYLPKDNSA
                     DFAGGESILDWLRQFASKEEDDNTFLRGFLGRMLFSGDEVNKPVNVLSGGEKVRVMLS
                     KLMLLKSNVLVLDDPTNHLDLESISSLNDGLKNFKESIIFASHDHEFIQTLANHIIVL
                     SKNGVIDRIDETYDEFLENAEVQAKVKELWKD"
     gene            4609..5634
                     /gene="trpS"
                     /locus_tag="VQU30_001333"
     CDS             4609..5634
                     /gene="trpS"
                     /locus_tag="VQU30_001333"
                     /EC_number="6.1.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000165445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tryptophan--tRNA ligase"
                     /protein_id="HET2447438.1"
                     /translation="MTKPIILTGDRPTGKLHIGHYVGSLKNRVLLQEEDKYDMFVFLA
                     DQQALTDHAKDPQTIVESIGNVALDYLAVGLDPNKSTIFIQSQIPELAELSMYYMNLV
                     SLARLERNPTVKTEISQKGFGESIPTGFLVYPIAQAADITAFKANYVPVGTDQKPMIE
                     QTREIVRSFNNAYNCDVLVEPEGIYPENERAGRLPGLDGNAKMSKSLNNGIYLADDAD
                     TLRKKVMSMYTDPDHIRVEDPGKIEGNMVFHYLDVFGRPEDAQEIADMKERYQRGGLG
                     DVKTKRYLLEILERELGPIRERRIEFAKDMGEVYNMIQKGSERAREVAGQTLSEVKGA
                     MGLHYFN"
     gene            5787..7265
                     /gene="guaB"
                     /locus_tag="VQU30_001334"
     CDS             5787..7265
                     /gene="guaB"
                     /locus_tag="VQU30_001334"
                     /EC_number="1.1.1.205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000073411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IMP dehydrogenase"
                     /protein_id="HET2447439.1"
                     /translation="MSNWDTKFLKKGFTFDDVLLIPAESHVLPNDADLTTKLADNLTL
                     NIPIITAAMDTVTESQMAIAIARAGGLGVIHKNMSIAQQADEVRKVKRSENGVIIDPF
                     FLTPEHTIAEADELMGRYRISGVPVVETLENRKLVGILTNRDLRFISDYNQPISNHMT
                     SENLVTAPVGTDLATAESILQEHRIEKLPLVDEEGSLSGLITIKDIEKVIEFPNAAKD
                     EFGRLLVAGAVGVTSDTFERAEALFEAGADAIVIDTAHGHSAGVLRKIAEIRAHFPDR
                     TLIAGNIATAEGARALYEAGVDVVKVGIGPGSICTTRVIAGVGVPQVTAIYDAAAVAR
                     EYGKTIIADGGIKYSGDIVKALAAGGNAVMLGSMFAGTDEAPGETEIFQGRKFKTYRG
                     MGSIAAMKKGSSDRYFQGSVNEANKLVPEGIEGRVAYKGAAADIVFQMIGGIRSGMGY
                     CGAANLKELHDNAQFIEMSGAGLKESHPHDVQITNEAPNYSM"
     gene            complement(7316..8413)
                     /gene="recF"
                     /locus_tag="VQU30_001335"
     CDS             complement(7316..8413)
                     /gene="recF"
                     /locus_tag="VQU30_001335"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000266665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA replication/repair protein RecF"
                     /protein_id="HET2447440.1"
                     /translation="MWLQHLSLKTFRNYKETKIDFNPKLNVFLGRNAQGKTNMLEAIY
                     FLALTRSHRTRTDKNLIHFDEEQLHLSGLVQKKTGSIPLEIELTQKGRVTKVNHLKQA
                     RLSDYVGHMNVVLFAPEDLQLIKGAPSIRRKFIDMELGQIKPIYLSDLTNYNHILKQR
                     NTYLKSAQKIDETFLSVLDDQLVDYGCRVMNHRLDFIKKLESFGRKKHFELSNQIEEL
                     SISYQSSVNITDKQNLSESFKIALEKSRSRDLFKKNTGVGPHRDDISFYINGMDASFG
                     SQGQHRSLVLSIKLAEIELMESITTESPILLLDDVMSELDNTRQLKLLETISQSIQTF
                     ITTTSLDHLQNLPENLSIFTIQDGKAAVNGN"
     gene            complement(8416..8784)
                     /gene="yaaA"
                     /locus_tag="VQU30_001336"
     CDS             complement(8416..8784)
                     /gene="yaaA"
                     /locus_tag="VQU30_001336"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000455867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S4 domain-containing protein YaaA"
                     /protein_id="HET2447441.1"
                     /translation="MEYKLFEEFITLQALLKELGITHSGGAIKSFLSEHSVYFNRELE
                     SRRGKKLRIGDKIDIPDMNIDILLTQSTSEEQDEYQADKVEKERIAKLVKKMNKGVKK
                     DKSKPASSPKSQQAPRFPGR"
     gene            8943..10193
                     /locus_tag="VQU30_001337"
     CDS             8943..10193
                     /locus_tag="VQU30_001337"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000424255.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="insulinase family protein"
                     /protein_id="HET2447442.1"
                     /translation="MELVHGISTHFIQSKKFKTNKITVRFTAPLSLDTIAGHMLSASM
                     LETANQMYPTSQDLRRHLASLYGTDMSTNCFRRGQSHIIELTFTYVRDEFLSRKNVLT
                     SQILELVKETLFSPVVVDNGFDPALFEIEKKQLLASLAADMDDSFYFAHKELDKLFFH
                     DERLQLEYSYLRNRILAETPQSSYSCFQEFLANDRIDFFFLGDFNEVEIQNVLESFGF
                     KGRKGDVKVQYCQPYSNILQEGMVRKNVGQSILELGYHCPSKYGDEKHLPMIVMNGLL
                     GGFAHSKLFTNVRENAGLAYTISSQLDLFSGFLRMYAGIDRENRNQARKMMNNQLLDL
                     KKGYFTELELEQTKEMIRRSLLLSQDNQSSLIERAYQNALLGKSSADFKSWIAKLEQV
                     DKDAICRAANNVKLQAIYFMEGIE"
     gene            10190..11473
                     /locus_tag="VQU30_001338"
     CDS             10190..11473
                     /locus_tag="VQU30_001338"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="insulinase family protein"
                     /protein_id="HET2447443.1"
                     /translation="MTKVVFEEKYYPAVKEMVYRTRLANGLTVALLPKKEFKEVYGSV
                     TVQFGSVDTLVTEVDGDVKQYPAGIAHFLEHKLFEREDSSDLMSAFTSLGADSNAFTS
                     FTKTNYLFSATDYFLENLDLLDELITSAHFTEASILTEQDIIQQEREMYQDDPDSCLF
                     FSTLANLYPGTPLATDIVGSEESISQINLTNLQENFTKFYKPVNMSLFLVGNFDVERV
                     QDYFESKELKDSDFQEVAREKLFLQPVKLTDSMRMEVSSPKLAIGVRGKREVSEADCY
                     RHHILLKLLFAMMFGWTSDRFQKCYESGKIDASLSLEVEITSRFHFVMLTMDTKEPVA
                     LSHQFRKAIRNFTKDLDITEEHLDIIKREMFGEFFSSMNSLEFIATQYDAFENGETIF
                     DLPKILQEITLEDVLDAGHHLIDDGDIVDFTIFPS"
     gene            11515..12336
                     /locus_tag="VQU30_001339"
     CDS             11515..12336
                     /locus_tag="VQU30_001339"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398726.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HET2447444.1"
                     /translation="MRKKTIGEVLRLARINQGLSLDELQKKTEIQLDMLEAMEADDFD
                     QLPSPFYTRSFLKKYAWAVELDDQIVLDAYDSGSMITYEEVDVDEDELTGRRRSSKKK
                     KKKTSFLPLFYFILFALSILIFVTYYVWNYIQTQPEEPSLSNYSVVQSTSSTSSVPHS
                     SSSSSSSIESAISVSGEGNHVEIAYKTSKETVKLQLAVSDVTSWVSVSESELEGGVTL
                     SPKKKSAEATVATKSPVTITLGVVKGVDLTVDNQTVDLSKLTAQTGQITVTFTKN"
     gene            12347..12892
                     /gene="pgsA"
                     /locus_tag="VQU30_001340"
     CDS             12347..12892
                     /gene="pgsA"
                     /locus_tag="VQU30_001340"
                     /EC_number="2.7.8.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000712151.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CDP-diacylglycerol--glycerol-3-phosphate
                     3-phosphatidyltransferase"
                     /protein_id="HET2447445.1"
                     /translation="MKKEQIPNLLTIGRILFIPIFIFILTIGNSIESHIVAAIIFAVA
                     SITDYLDGYLARKWNVVSNFGKFADPMADKLLVMSAFIMLIELGMAPAWIVAVIICRE
                     LAVTGLRLLLVETGGTILAAAMPGKIKTFSQMFAIIFLLLHWTLLGQVLLYVALFFTI
                     YSGYDYFKGSAYVFKGTFGSK"
     gene            12889..13716
                     /locus_tag="VQU30_001341"
     CDS             12889..13716
                     /locus_tag="VQU30_001341"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter ATPase"
                     /protein_id="HET2447446.1"
                     /translation="MKSIIDVKNLSFRYKENQNYYDVKDITFHVKRGEWLSIVGHNGS
                     GKSTTVRLIDGLLEAESGEIVIDGQRLTEENVWNIRRQIGMVFQNPDNQFVGATVEDD
                     VAFGLENQGLSRQEMKKRVEEALALVGMLDFKKREPARLSGGQKQRVAIAGVVALRPA
                     ILILDEATSMLDPEGRRELIGTVKGIRKDYDMTVISITHDLEEVAMSDRVLVMKKGEI
                     ESTSSPRELFSRNDLDQIGLDDPFANQLKKSLSQNGYDLPENYLTESELEDKLWELL"
     gene            13701..14540
                     /locus_tag="VQU30_001342"
     CDS             13701..14540
                     /locus_tag="VQU30_001342"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000510406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter ATPase"
                     /protein_id="HET2447447.1"
                     /translation="MGIALENVNFTYQEGTPLASAALSDVSLTIEDGSYTALIGHTGS
                     GKSTILQLLNGLLVPNQGSVRVFDTLITSTSKNKDIRQIRKQVGLVFQFAENQIFEET
                     VLKDVAFGPQNFGVSEEDAVKTAREKLALVGIDESLFDRSPFELSGGQMRRVAIAGIL
                     AMEPAILVLDEPTAGLDPLGRKELMTLFKKLHQSGMTIVLVTHLMDDVAEYANQVYVM
                     EKGRLVKGGKPSDVFQDVVFMEEVQLGVPKITAFCKRLADRGVSFKRLPIKIEEFKES
                     LNG"
     gene            14533..15327
                     /locus_tag="VQU30_001343"
     CDS             14533..15327
                     /locus_tag="VQU30_001343"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000377903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter transmembrane
                     protein EcfT"
                     /protein_id="HET2447448.1"
                     /translation="MDSMILGRYIPGDSIVHRLDPRSKLLAMMLLILIVFWANNPLTN
                     LILFIATGIFIALSGVSLSFFIQGLKSMFFLIAFTTIFQLFFISNGNVLFEFSFVRIT
                     DYALQQAGIIFCRFVLIIFFSTLLTLTTMPLSLASAVEALLAPLKRVKVPVHEIGLML
                     SMSLRFVPTLMDDTTRIMNAQKARGVDFGEGSIVQKVKAMIPILIPLFATSLKRADSL
                     AIAMEARGYQGGKGRSQYRQLKWTLKDTLTILVILVLGCCLFFLKS"
     gene            15386..16204
                     /gene="mreC"
                     /locus_tag="VQU30_001344"
     CDS             15386..16204
                     /gene="mreC"
                     /locus_tag="VQU30_001344"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001078980.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rod shape-determining protein MreC"
                     /protein_id="HET2447449.1"
                     /translation="MNRFKKSKYVIIVFVTVLLVSALLATTYSSTIVTKLGDGISLVD
                     RVVQKPFQWFDSVKSDLAHLTRTYNENESLKKQLYQLEVKSNEVESLKTENEQLRQLL
                     DMKSKLQATKTLAADVIMRSPVSWKQELTLDAGRSKGASENMLAIANGGLIGSVSKVE
                     ENSTIVNLLTNTENADKISVKIQHGSTTIYGIIIGYDKENDVLKVSQLNSNSDISAGD
                     KVTTGGLGNFNVADIPVGEVVATTHSTDYLTREVTVKLSADTHNVDVIELVGNS"
     gene            16204..16698
                     /gene="mreD"
                     /locus_tag="VQU30_001345"
     CDS             16204..16698
                     /gene="mreD"
                     /locus_tag="VQU30_001345"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001249461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rod shape-determining protein MreD"
                     /protein_id="HET2447450.1"
                     /translation="MRQLKRVGVFLLLPFFVLIDAHISQLLGSFFPHVHLASHFLFLF
                     LLFETIEVSEYLYLVYCFVIGLVYDVYFFHLIGITTLLFILLGAFLHKLNSVILLNRW
                     TRMLAMIVLTFLFEMGSYLLAFMVGLTVDSMSIFIVYSLVPTMILNFLWITVFQFIFE
                     KYYL"
     gene            16792..17970
                     /locus_tag="VQU30_001346"
     CDS             16792..17970
                     /locus_tag="VQU30_001346"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000727004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CHAP domain-containing protein"
                     /protein_id="HET2447451.1"
                     /translation="MKKKILASLLLSTVMVSQVAVLTTAHAETTDDKIAAQDNKISNL
                     TAQQQEAQKQVDQIQEQVSAIQAEQSNLQAENDRLQAESKKLEGEITELSKNIVSRNQ
                     SLEKQARSAQTNGAVTSYINTIVNSKSITEAISRVAAMSEIVSANNKMLEQQKADKKA
                     ISEKQVANNDAINTVIANQQKLADDAQALTTKQAELKAAELSLAAEKATAEGEKASLL
                     EQKAAAEAEARAAAVAEAAYKEKRASQQQSVLASANTNLTAQVQAVSESAAAPVRAKV
                     RPTYSTNASSYPIGECTWGVKTLAPWAGDYWGNGAQWATSAAAAGFRTGSTPQVGAIA
                     CWNDGGYGHVAVVTAVESTTRIQVSESNYAGNRTIGNHRGWFNPTTTSEGFVTYIYAD
                     "
     gene            18194..18973
                     /gene="rpsB"
                     /locus_tag="VQU30_001347"
     CDS             18194..18973
                     /gene="rpsB"
                     /locus_tag="VQU30_001347"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000268478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S2"
                     /protein_id="HET2447452.1"
                     /translation="MAVISMKQLLEAGVHFGHQTRRWNPKMAKYIFTERNGIHVIDLQ
                     QTVKYADQAYDFMRDAAANDAVVLFVGTKKQAADAVAEEAVRSGQYFINHRWLGGTLT
                     NWGTIQKRIARLKEIKRMEEDGTFEVLPKKEVALLNKQRARLEKFLGGIEDMPRIPDV
                     MYVVDPHKEQIAVKEAKKLGIPVVAMVDTNTDPDDIDVIIPANDDAIRAVKLITAKLA
                     DAIIEGRQGEDAVAVEAEFAASETQADSIEEIVEVVEGDNA"
     gene            19052..20092
                     /locus_tag="VQU30_001348"
     CDS             19052..20092
                     /locus_tag="VQU30_001348"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003053075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor Ts"
                     /protein_id="HET2447453.1"
                     /translation="MAEITAKLVKELREKSGAGVMDAKKALVETDGDIEKAIELLREK
                     GMAKAAKKADRVAAEGLTGVYVNGNVAAVIEVNAETDFVAKNAQFVELVNTTAKVIAE
                     GKPANNEEALALIMPSGETLEAAYVSATATIGEKISFRRFALIEKTDAQHFGAYQHNG
                     GRIGVISVVEGGDEALAKQLSMHIAAMKPTVLSYKELDEQFVKDELAQLNHVIDQDNE
                     SRAMVNKPALPHLKYGSKAQLTDDVIAQAEADIKAELAAEGKPEKIWDKIIPGKMDRF
                     MLDNTKVDQAYTLLAQVYIMDDSKTVEAYLESVNASVVEFARFEVGEGIEKAANDFEA
                     EVAATMAAALNN"
     gene            20339..20680
                     /gene="tnpB"
                     /locus_tag="VQU30_001349"
                     /pseudo
     CDS             20339..20680
                     /gene="tnpB"
                     /locus_tag="VQU30_001349"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001846105.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS66 family insertion sequence element accessory
                     protein TnpB"
     gene            complement(20816..21103)
                     /locus_tag="VQU30_001350"
                     /pseudo
     CDS             complement(20816..21103)
                     /locus_tag="VQU30_001350"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611577.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            21094..21492
                     /locus_tag="VQU30_001351"
     CDS             21094..21492
                     /locus_tag="VQU30_001351"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000646892.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HET2447454.1"
                     /translation="MKSPIPKAPLAHNFGSASIIAHTIHQKFNLKVPNYRQEEDWARM
                     GLPIIRKEISNWHIKTSQYYLEPLYNLLRERLLTQPLLHADETSYRVLESDSQLTYYW
                     TFLSGKAEKQGITLYHHVLIDLFISYFNPL"
BASE COUNT         6840 a         3484 c         4416 g         6797 t
ORIGIN      
        1 gctttagatc tttagaaaac cttgaacaag ctattgtgga ctacattgat tactacaaca
       61 acaaacgaat taaggtaaaa ctaaaagaac ttagccctgt gcaatacaga actaaatcct
      121 tcggataaat taattgtcta actttttggg gtcagtacat taactggtcg attttttatg
      181 ccttagatga ctttcgtctg tgattataga ttccaaatag taagagagaa gtaaaggaac
      241 agattgctcc agtaataaaa ccattgggaa tgaaggaaag tgtaatagtt cctttcccct
      301 tgggaatgtc aactttcata aatccagttt gagcttgttt aatttctatt ttcttaccat
      361 cttggtaggc agaccaacct ttgtcataag gaatggtgaa gaaaatagat gtatcttgtt
      421 ggacatcata tgtagcaaaa accttgtttt tagaagttga tactgtgaca ggttgttctt
      481 taattttttg aattgcctcg gtgaaagttt tggtatctaa acgatagaag gtaggagatt
      541 caaatgatac ttgtgaattt ccagggaaac taacattgat attgaaagtt tttttctctt
      601 tagtatatcc tagattaaag aaggagaaga cattatcagt tgtaaaagtc tttttttcac
      661 catttacaag gatgtcaacc ttcttttgtt tatcgttaga aaagtgaagg tttatgaaag
      721 agagataaac ttggctgttt tctggaactt caatttgata ctggattgct gcatcttcat
      781 ttgaagaact tgtgacacta atcaaatcat tagtattttc tgttttttca taaggtattg
      841 gagaaaaata atcaaaattg acgttagcaa gttgatttaa aaatgaggcc tgattatcca
      901 aggtatgttc attgaacttg acatcattgt aaacagattg actagcaact gcaatcggaa
      961 gagagtattg attttcatat agggtaagat tatctttttg atagatatct ttaaagccat
     1021 acttatcaat aggactgtct gagatattgt actggatacc aaataaacta tcagccaaaa
     1081 tactattatt tgcatatcgg agattgagat tagtcccaga ggatttaaaa ccaagtttat
     1141 ctaaagtaga gcttgatgaa cgatttcgaa cagatgaaaa ttgagagatt ccattgtagt
     1201 tgaatttcat actgtcattt cctgtctgag tttgtagttt ttcagtacga gtaaattgat
     1261 ttccaatata tgttgagaaa gattccatag ctgggatatc tcgactataa gcacttcgag
     1321 aagcaaatcc ccattcctta gcaattccgt ccatttgaga tgaagcattt aaactcattt
     1381 caaccagtat aaataaagag attagaatgg caaatagatt cacagatata aactttttga
     1441 taactgcaag gagtaaaaga gaatagacaa ccaaaaattc aagagtaagc agaatattca
     1501 aatctgttaa aaaagaataa tgcgatttta gatagatggt agctaaaaat cctgctacta
     1561 caagaaaaag cgaaactaaa aaattccaga ctttaagttc tttcagacgc tttaagactt
     1621 ctgctgctgt gtaaattaac aaggtagaga aaatccaagc atagcgatgt aaaaacatgt
     1681 ttggagtatg catgccttgc caaaataagt caagagcttc tatgtaaaag cttgcaatta
     1741 gaaatgcaaa gaatattaca tatatgagtt tcacgtgaaa cttaatagat ttcagcgtaa
     1801 aaaataaaat ggtcaaaata aagggaaata gtccaacaaa aatcattggg atggccccat
     1861 actttgttgt gtcaaaggaa ccaatgaatt gcttagcaaa gagatcaaga taccagctac
     1921 tttcagtttg aaactttgta acttcagtca atttttcccc atgtgtctgt aaatcaaata
     1981 gagtgggaag agtcataatc aaactagcca taccagctaa aaaggagata actatgaaat
     2041 caagaacaga tgattttcga gtcttaaagt cccacgaaat ttgacagaga taccagaaaa
     2101 taagaaacaa tactgtcata tatccaaaat aataattttg aataaataag attgacagac
     2161 ttgtaaagta caataggagt ttcttttcag ttatcagtag atgtaaacca gttataatta
     2221 aaggaatcaa gataaaaaca tctagccagg tttttatctc taattgactg acagtgaaac
     2281 tcatcagagc ataggaagta gataaggcta gttttaaagt ctgagggata gattgaaaca
     2341 atttattcaa actaaaaaag gttgacagac caatcaatcc aaattttaag agagtggtca
     2401 gatagacagc atctggcata ttcgttagat caaaaaagta aactagaggc gcgagaaaac
     2461 tacccaagta ataactagat agggcataga agtttagccc tagaccactt gtaaaggtgt
     2521 aaaacagact actatttcca tgtaggatat ttcgtaaggc tacatcaaaa ataacgtatt
     2581 gatgaaagcc atctcctaat agaggagagt tgtcgctatt ccagtagata ccttgagata
     2641 gatatactcc agacataatc actacaggaa tgatgaaaga aataaaatag gttcgatatg
     2701 tttttaaaaa tgatttcatg ttacctcgta gaatgataga aaactcagtt ggttaaccca
     2761 actgagtttt gaagttttat ttagtctttc caaagttctt taacttttgc ttgtacttct
     2821 gcattttcta ggaattcatc gtaggtttca tcgatacggt caatgacgcc atttttagat
     2881 aagacaatga tatggttagc caaagtttga ataaactcgt ggtcatggct ggcaaagatg
     2941 attgattctt taaagttttt cagtccatca ttcaagcttg agatagattc caagtccaag
     3001 tgatttgttg gatcatcaag tacaaggaca tttgatttta agagcatgag ttttgaaagc
     3061 atgacacgaa ctttttctcc ccctgacaag acatttacag gtttgttaac ttcatctcca
     3121 gagaagagca tacggccgag gaaaccacgt aggaaagtat tgtcatcttc ttctttactt
     3181 gcgaattgac gcaaccagtc aagaattgat tctcctcctg caaaatcagc tgagttatct
     3241 tttggtaggt aagattgact agttgtaact ccccacttga cagttccttc atagtcaata
     3301 tctcccatga ttgcacgaat taatgcagtc gtttgaatat cattttgtcc aataagtgct
     3361 gtcttatcat ctggacgcaa gatgaaacta atattatcca agatagtttc accatcaatc
     3421 tttacagtta gattttctac tgtcaagaga tcattaccaa tctcacgttc cgctttaaag
     3481 ttgataaatg gatatttacg actagatggt acaatctctt ctagctcaat cttatcaagc
     3541 attttcttac gtgatgttgc ctgccttgac ttagaagcat tggcagagaa acgagcaacg
     3601 aattcttgca attgtttaat tttttcttct gctttagcat tacggtctgc tagcaattta
     3661 gcagcaagct cagaagattc cttccagaag tcgtagtttc cgacatagag tttgattttt
     3721 ccaaagtcaa ggtcggccat gtgagtacaa actttgttta agaagtgacg gtcgtgggat
     3781 actacgataa ctgtgttatc aaagtcaatc aagaagtctt ctaaccaagt aatcgattgg
     3841 atatccaaac cgttagtagg ctcgtccaag agaagaacat ctggtttacc aaaaagtgct
     3901 ttggcgagga gaacctttac tttttcaccg ttggccaatt cgctcatgtt ttggtagtgt
     3961 aattcttctg gaatgtttag gttttgaagt agttgagagg cttcactctc tgcttcccaa
     4021 cctccaagtt cggcaaactc tccttcgagt tcggcagcac gaaccccgtc ctcgtctgag
     4081 aaatcttcct tcatgtagat agcatctttc tctttcatga tgctataaag tttttcattt
     4141 cccatgataa cgacatcaat ggcacgttca tcttcgtagt caaagtgatt ttgacgaaga
     4201 acagagagac gttcatctgg accaagagag atgtgaccag tagtaggttc gatatctcca
     4261 gctaaaattt ttaaaaaggt tgattttccg gcaccattag caccgattaa tccgtaagta
     4321 tttccttctg taaatttgat attgacatca tcaaaaagtt tgcgatcact aaaacgtagt
     4381 gaaacatcag atactgtaag caatgttttt ctcctatatg tgtaatatat ttattctact
     4441 agaaaataca gaaatattca aatttttatt tgtcaatttt gtgtaaatta tatttacagt
     4501 atcctttaca caaatctgta aaaagcaagg ctgatttatt ttgataaatt acggttattt
     4561 cattaaaaaa atgctataat tgaaaggact atatcgaagg agaacaaaat gactaaaccc
     4621 attattttaa caggagaccg tccaacagga aaattgcata ttggacatta tgttggaagt
     4681 ctcaaaaatc gagtattatt acaggaagag gataagtatg atatgtttgt gttcttggct
     4741 gaccaacaag ccttgacaga tcatgccaaa gatcctcaaa ccattgtaga gtctatcgga
     4801 aatgtggctt tggattatct tgcagttgga ttggatccaa ataagtcaac tatttttatt
     4861 caaagccaga ttccagagtt ggctgagttg tctatgtatt atatgaatct agtttcgtta
     4921 gcacgtttgg agcgaaatcc aacagtcaag acagagattt ctcagaaagg atttggagaa
     4981 agcattccga caggattctt ggtctatcca atcgctcaag cagctgatat cacagctttc
     5041 aaggctaatt atgttcctgt tgggacagat cagaaaccaa tgattgagca aactcgtgaa
     5101 attgttcgtt cttttaacaa tgcatataac tgtgatgtct tggtagagcc ggaaggtatt
     5161 tatccagaaa atgagagagc agggcgtttg cctggtttag atggaaatgc taaaatgtct
     5221 aaatcactaa ataatggtat ttatttagct gatgatgcgg atactttgcg taaaaaagta
     5281 atgagtatgt atacagatcc agatcatatc cgcgttgagg atccaggtaa gattgaggga
     5341 aatatggttt tccattatct agatgttttt ggtcgtccag aagatgctca agaaattgct
     5401 gatatgaaag aacgttatca acgaggtggt cttggtgatg tgaagaccaa gcgttatcta
     5461 cttgaaatat tagaacgtga actgggtcct attcgtgagc gccgtattga atttgctaag
     5521 gatatgggag aagtttataa tatgattcaa aaaggtagtg aaagagcgcg tgaagttgcg
     5581 ggtcaaaccc tatctgaggt aaaaggggca atgggacttc attactttaa ctaagtttat
     5641 tttacaagaa actatcattt ctatctcgaa gaaaagatag tttttttatt tacccctgta
     5701 acatttgaca aatttttata gaatggtatg atagatacaa tataaaaaga gtcaagctca
     5761 aaaagaaaga aaagaggaaa cttcgaatgt ctaattggga cactaaattt ttgaaaaaag
     5821 gttttacctt tgatgatgta ttgcttattc cagctgaaag tcatgtgttg cctaacgatg
     5881 cagatttaac aactaaattg gcagataatt tgactttaaa tatcccaatt attaccgctg
     5941 ccatggacac agttacagag agtcaaatgg ccattgctat tgctcgtgca ggcggtctcg
     6001 gagttatcca taaaaacatg tcaattgctc aacaagcaga cgaggttcgt aaggtaaaac
     6061 gttctgaaaa tggagttatt attgatccgt tcttcttgac gcctgaacat acaattgctg
     6121 aagcagatga gcttatgggt cgttaccgca tcagtggtgt tccagttgtt gaaacacttg
     6181 aaaatcgtaa attggttggt attttgacaa accgagatct tcgttttatt tcagattata
     6241 atcaaccaat ttcaaaccat atgactagtg aaaatcttgt tactgctcct gtgggtacgg
     6301 atcttgcaac ggctgagagt attcttcaag agcatcgtat tgaaaaactt ccgttggtcg
     6361 atgaagaagg cagtctttct ggtttgatca ctatcaaaga tattgaaaaa gttattgagt
     6421 ttccaaatgc ggctaaagat gagtttggtc gtcttctagt tgcaggtgca gtaggtgtta
     6481 cttcagatac atttgaacgt gcagaggctc tttttgaggc aggagcggat gcgattgtta
     6541 ttgatactgc acatggtcat tctgcaggtg tcttgcgtaa aattgccgag attcgtgctc
     6601 atttcccaga tcggactttg attgctggaa atattgctac tgctgaaggt gcacgtgccc
     6661 tttatgaagc gggtgtagac gttgttaagg ttggtattgg accaggttct atctgtacta
     6721 ctcgtgtgat tgctggtgtt ggtgttccgc aagtaacagc tatctacgat gctgcagctg
     6781 ttgcgcgcga atatggtaaa acgattattg ctgacggtgg gatcaagtat tctggagata
     6841 ttgtaaaagc acttgctgca ggtggaaatg ctgttatgct tggatctatg tttgctggaa
     6901 ctgatgaagc tccaggcgaa actgaaatct tccaaggacg taaattcaag acttaccgtg
     6961 gtatgggatc aattgctgct atgaagaaag gttcaagcga ccgttatttc caaggttctg
     7021 tcaatgaagc aaacaagctt gttccagaag gaattgaagg tcgtgttgct tataaaggag
     7081 cggcagctga tattgttttc caaatgattg gtggtattcg ctctggtatg ggttactgtg
     7141 gtgcagctaa ccttaaagaa ctacacgata atgctcaatt tattgaaatg tctggtgctg
     7201 gtttgaaaga aagccatcct catgatgtgc aaattactaa tgaggcacca aattattcta
     7261 tgtaaaaaac aatgaaaaga actccagtga aaacaggagt tcttttacaa tgttgtcaat
     7321 ttccatttac agcagcttta ccatcctgaa tagtgaagat acttagattt tctggcagat
     7381 tttgaagatg gtctaagctt gttgttgtga taaaggtttg gattgattga gaaatcgttt
     7441 ctaataattt taactgtcta gtgttgtcaa gttcactcat cacatcgtca agcagtaata
     7501 taggagattc tgtggtaatg ctttccatta attcgatttc tgctaatttt atcgagagga
     7561 cgagactacg atgttgacct tggcttccga aactagcatc catcccattt atataaaaag
     7621 aaatgtcatc tcgatgagga ccgacaccag tattcttttt aaataaatct ctggatctac
     7681 ttttttctaa agcaattttg aaagattcgg ataagttttg tttgtcagtt atattgacag
     7741 aagattgata ggatattgac aactcttcga tctgattaga gagttcaaaa tgtttcttac
     7801 gcccaaatga ttctagtttt tttatgaaat ctaagcggtg attcattaca cgacatccat
     7861 aatcaactag ctgatcatct aacacagaaa ggaatgtttc atctattttt tgagctgatt
     7921 ttaggtaagt gtttctttgc tttaggatgt ggttataatt ggttaagtca gataaataga
     7981 ttggcttaat ttgcccaagt tccatatcaa tgaattttcg tcgaatcgaa ggtgctcctt
     8041 taattagttg taaatcttca ggagcaaata agacaacatt catgtgtcct acataatctg
     8101 aaaggcgtgc ctgttttaag tgattaactt ttgttacacg gcctttttgt gttagttcga
     8161 tttctagggg aatggatcca gtttttttct gaacgagacc tgaaagatga agttgttcct
     8221 catcaaaatg aatgagattt ttatctgttc gagttcgatg actacgcgtt aaggctaaaa
     8281 aatagatagc ctctaacatg tttgtttttc cttgtgcatt acgtcccaaa aagacattca
     8341 atttaggatt aaagtctatt ttcgtttctt tgtaattacg aaaagtcttg agagatagat
     8401 gttgtagcca catgattatc taccagggaa tcgtggagct tgttggcttt taggtgatga
     8461 agcaggtttc gatttgtctt ttttaactcc cttattcatc tttttgacaa gtttagcgat
     8521 ccgttctttt tcaactttat cagcttggta ttcatcttgt tcttcagaag tagattgtgt
     8581 caacaagatg tcaatgttca tgtcagggat gtcaatttta tcgccaatac gaagtttttt
     8641 accacgacga ctctctaatt ccctattaaa gtaaacagaa tgttcagaga gaaatgattt
     8701 aatagctcct ccgctatgtg taattccaag ttctttgagt agtgcttgga gggtaataaa
     8761 ttcttcaaat aatttgtatt ccataattca cctcaatctt tggtattata ccatattttc
     8821 ctaaaaatag tgagagatac agcgagaaat gtaagcgatt tttatttcaa aagtgttaca
     8881 gggaacaaga aaatttcagg ttttcgtgat ataatagaag tctgtatata aggagataaa
     8941 tcatggagtt agtgcatgga atttcaacac attttatcca atcaaaaaag tttaaaacaa
     9001 acaaaattac cgtgcgtttt accgctccat tatcccttga tacgattgca ggtcacatgt
     9061 tgagtgcaag tatgctagag actgctaatc agatgtaccc cacttctcaa gatttgagga
     9121 gacacttggc cagtctatac ggtacagata tgtcaaccaa ttgtttcaga agagggcaaa
     9181 gccacattat agaattgaca tttacctatg ttcgtgatga gtttttaagt aggaaaaacg
     9241 tgctaacttc tcagattttg gaacttgtaa aagaaactct tttttcaccc gtagtagttg
     9301 ataatgggtt tgatccggcc ttatttgaaa ttgagaaaaa acaattgcta gcaagtttag
     9361 cagctgatat ggatgattct ttttattttg cacataaaga attggataaa ttgttttttc
     9421 atgatgaacg tcttcaattg gaatatagtt atttacgaaa tcgtatttta gctgaaactc
     9481 cacaaagttc ttattcttgt ttccaagaat ttttagccaa tgatcgaata gatttctttt
     9541 tcctaggtga ttttaatgag gttgaaattc aaaatgtatt agaatcattt ggctttaaag
     9601 gtcgaaaagg agatgtgaag gttcagtatt gtcaacctta ttctaatatc cttcaggaag
     9661 gtatggttcg gaaaaatgtg ggacaatcca ttttggaatt aggttatcat tgcccttcta
     9721 aatatggtga tgagaaacat ttacccatga ttgtaatgaa tggtttactt ggtggatttg
     9781 ctcactctaa actttttaca aatgtccgtg aaaatgctgg attagcttat actatttcaa
     9841 gtcagctcga tttatttagt ggattcttga ggatgtatgc tggtattgac cgagaaaatc
     9901 gtaaccaggc tcgtaaaatg atgaataatc aactgcttga tttaaaaaaa ggttatttta
     9961 cagagcttga gttagagcag accaaggaaa tgattcgtcg gtctttgtta ctttctcaag
    10021 ataaccaatc ttcattgatt gaacgtgctt atcaaaatgc cttacttgga aaatcttcag
    10081 cagattttaa aagttggatt gcaaaactcg agcaagttga caaagatgct atttgtagag
    10141 cagctaacaa tgtgaaacta caagcgattt actttatgga aggaatagaa tgacaaaggt
    10201 tgtttttgaa gaaaaatact atccagctgt aaaagaaatg gtttatcgaa ctcgtttggc
    10261 aaatggattg acagtagctc ttttgcctaa aaaggaattt aaagaggttt acgggagtgt
    10321 aactgtacag tttggttcgg tagatacgct tgtcacagaa gttgatggag atgtaaaaca
    10381 atatcctgca ggaattgctc attttcttga acataaatta tttgaaagag aagattctag
    10441 cgatttgatg tcggctttta cgagtctagg tgcagatagt aatgccttta caagctttac
    10501 aaaaacaaac tatctttttt cagcaacgga ttatttttta gaaaatttag atttacttga
    10561 tgaattgata acatcagcac actttactga agcttccatt ctgacagagc aggatattat
    10621 tcagcaagaa cgagaaatgt accaagatga tccagattcg tgtttattct tttcaacttt
    10681 agcgaatttg tatcctggta cacctttagc aactgatata gttggaagtg aggagtccat
    10741 ttcccaaatc aatctaacta atttgcaaga aaattttaca aagttttaca aacctgtaaa
    10801 catgtctctg tttttagttg gtaattttga tgtggagcga gtacaggact attttgaaag
    10861 caaagaactg aaagattcag attttcagga agtagcaaga gaaaagttgt ttttacagcc
    10921 tgtaaagcta acagatagta tgagaatgga agtatcttct cccaaactag cgattggagt
    10981 tagaggtaag cgagaagttt ctgaagcgga ttgctatcga catcatattt tattaaaatt
    11041 attgtttgca atgatgtttg gttggacttc ggatcgtttt caaaaatgtt atgaatcagg
    11101 taaaattgat gcgtccttat ctctggaagt tgaaataaca agtcgctttc attttgtcat
    11161 gttgacaatg gatacgaaag agccagttgc tttgtctcat caatttagga aggctattcg
    11221 taattttaca aaggatttag atattacaga ggaacattta gatattatca aaagagagat
    11281 gtttggcgaa tttttcagta gcatgaactc tcttgaattt attgcaacgc aatatgatgc
    11341 ttttgaaaat ggtgagacaa tttttgattt gccgaaaatt ttacaggaaa ttactttaga
    11401 ggatgtcctt gatgctggac atcatttaat agatgatggt gacatagttg attttacaat
    11461 atttccatcg tagtaaccta tcataataga cactagaaag aagggatgac aagtatgaga
    11521 aaaaaaacaa ttggagaggt tttacgatta gctagaatca atcagggatt gagtttagat
    11581 gaattgcaga aaaagacaga aatccagtta gatatgttgg aagcaatgga agcagacgat
    11641 ttcgatcaac ttccaagtcc tttttacacg cgttctttct tgaaaaaata tgcatgggct
    11701 gttgagttag atgaccaaat tgttttggat gcttatgatt ctgggagtat gattacttat
    11761 gaggaagtag atgttgatga agatgagttg acaggtcgta gacgttcaag taagaaaaag
    11821 aagaaaaaaa catcattttt acctttattt tattttatcc tttttgcttt atcgatttta
    11881 atttttgtga cttattatgt ttggaactat attcaaactc aaccagagga gccttctctt
    11941 tctaattaca gtgtggttca atcaacaagt tcaactagct ctgttcccca ctcctcaagt
    12001 agtagttctt ctagtataga atcagctata agtgtatcag gcgaaggaaa tcatgtagaa
    12061 atcgcttata agacaagtaa ggaaacagtt aaattgcaat tggcagtttc agatgttaca
    12121 agttgggtca gtgtttcaga aagcgaactt gagggcggtg taaccttatc gccaaagaag
    12181 aaaagtgcag aagcaacagt tgcaactaaa agtcctgtaa caattacgtt aggtgttgta
    12241 aaaggtgttg atttgacagt agataatcag actgttgatt tatcgaaatt aacagctcag
    12301 actggacaaa tcactgtaac ctttactaaa aattaaggaa aaacgaatga aaaaagaaca
    12361 aattcccaat ctcttaacaa taggtcgaat tctctttata cctattttta tctttatttt
    12421 aacgatagga aattcgatag agagtcatat agttgcagct attatctttg ctgttgccag
    12481 tattaccgac tatttagatg gatatttagc tcgtaaatgg aatgtggtca gtaattttgg
    12541 taaatttgca gatcctatgg cggataagtt actagttatg tcggctttta ttatgttgat
    12601 tgagttaggt atggctccgg cttggattgt tgcagtgatt atatgtcgtg agttagctgt
    12661 gacaggttta aggcttttat tggttgaaac tggtggaaca attttagcag cagcaatgcc
    12721 tggaaaaatt aaaactttta gtcagatgtt tgctattatt ttcttgctat tacattggac
    12781 tttgcttggt caagttctac tttatgtagc cttatttttc actatctact ctggctatga
    12841 ctattttaag ggtagtgcct atgtatttaa agggacattt ggttcgaaat gaaatcaata
    12901 attgatgtaa aaaatctttc ttttcgctat aaagaaaatc agaactacta cgatgtgaag
    12961 gatattacgt ttcacgtgaa acgtggagaa tggctttcga ttgtagggca taatggtagt
    13021 ggtaaatcaa cgacggttcg attaattgat ggcttactgg aagcagaatc cggagagatt
    13081 gtaattgatg gccaacgttt gactgaggaa aatgtttgga atatacgtcg tcaaatcggt
    13141 atggtttttc aaaatccaga caatcaattt gttggagcga ctgttgaaga tgatgttgct
    13201 tttggtttgg aaaatcaggg actttctcgt caagaaatga aaaagagagt ggaagaagct
    13261 ctggctttag ttggcatgtt ggactttaaa aagagagagc cagcgcgtct atcaggtggt
    13321 caaaagcaac gtgtggccat tgcaggtgtt gtagccctaa gaccagctat tttaatctta
    13381 gatgaagcaa cgagtatgtt ggatcctgag gggcgtagag aacttattgg gacagtaaaa
    13441 ggaattcgaa aagactatga tatgacggtc atttctatta cccatgattt ggaagaagtc
    13501 gccatgagtg atcgcgtatt ggtcatgaaa aaaggggaaa ttgaatcaac tagtagtcca
    13561 agggagcttt tctctcgaaa tgatttagat caaattggat tagacgatcc ttttgctaat
    13621 caattaaaaa aatctttgag ccagaatggc tatgatttac ctgaaaatta tttgacagaa
    13681 agtgagctag aggataagct atgggaattg ctctagaaaa tgtgaatttt acatatcaag
    13741 aaggtactcc cttagcttca gcagctttgt cggatgtttc tttgacgatt gaagatggct
    13801 cttatacagc tttaattggg cacacaggta gtggtaaatc aactatttta caactcttaa
    13861 atggtttatt ggtgccaaat caagggagtg tgagggtttt tgatacctta atcacctcga
    13921 cttctaaaaa taaagatatt cgtcaaatta gaaaacaggt tggcttggta tttcagtttg
    13981 ctgaaaatca gatttttgaa gaaacggttt tgaaggacgt tgcttttgga ccgcaaaatt
    14041 ttggagtttc tgaagaagat gctgtgaaga ctgcgcgtga gaaactggct ctggttggaa
    14101 ttgatgaatc actttttgat cgtagtccgt ttgagctgtc agggggacaa atgagacgtg
    14161 ttgccattgc aggcatactt gccatggagc cagctatatt agtcttagat gagccaacag
    14221 ctggtctaga tcctctaggg agaaaagagt tgatgaccct gttcaaaaaa ctccaccagt
    14281 cagggatgac catcgtcttg gtaacgcatt tgatggatga tgttgctgaa tatgcgaatc
    14341 aagtctatgt aatggaaaag ggacgtttag taaagggggg caaaccaagt gatgtctttc
    14401 aagacgttgt ttttatggaa gaagttcagt tgggagtacc taaaattacg gccttttgta
    14461 aacgattggc tgatagaggc gtgtcattta aacgattacc gattaagata gaggagttca
    14521 aggagtcgct aaatggatag tatgatttta gggcgttata tcccagggga ttcgattgtt
    14581 caccgattgg atccacgtag caaattgctt gctatgatgc tactgatttt gattgtgttt
    14641 tgggctaata accccttgac gaatctgatt ctttttatag cgacagggat atttattgcc
    14701 ttgtcaggag tatctctttc attttttatt cagggcttga agtctatgtt tttcttgatt
    14761 gccttcacaa ctatttttca actatttttc atttctaatg ggaatgtttt atttgagttt
    14821 tcgtttgtga gaatcacgga ttatgctttg caacaagctg ggattatttt ttgtcgcttt
    14881 gtattgatta ttttcttttc aactttgtta accttaacaa ccatgccttt aagtttggca
    14941 tcagctgtcg aagctttatt agcaccttta aagcgtgtga aagttccagt tcatgaaatt
    15001 ggattgatgc tgtctatgag tttgcgtttt gtcccaacct tgatggatga tacgactcgg
    15061 attatgaatg cacagaaagc tcgtggagtg gattttggag aaggaagcat cgttcaaaaa
    15121 gtaaaggcga tgattcccat tttgattcct ctttttgcga caagtttaaa acgtgcagat
    15181 tccttggcta tcgctatgga agcgcgtggc tatcagggtg gaaaaggcag aagtcaatac
    15241 cgacaattga aatggactct aaaggatacg ctgaccattc ttgttattct cgtacttggt
    15301 tgttgtttat ttttcttaaa atcttagtag ctttcaggaa ttgataaaaa gttactgtaa
    15361 cagtttttga tataaaggta ggaatatgaa ccgttttaaa aaatcaaaat atgtcattat
    15421 tgtttttgtc actgttctgc ttgtgtcagc tctcttagcg acgacttatt caagtacaat
    15481 tgtgacaaaa ttaggagatg gaatctcatt ggttgataga gttgtacaaa aaccttttca
    15541 gtggtttgat tctgtcaaat cagatttggc tcatttgaca cgaacatata atgaaaatga
    15601 aagtttgaag aaacagcttt accaattaga agttaaatca aatgaggtgg aaagtttaaa
    15661 gacagaaaat gaacaactgc gccaattgct tgatatgaag tctaaattgc aagccacaaa
    15721 gactttagca gcagatgtta ttatgcgttc tccggtatct tggaagcagg agttgacctt
    15781 agatgcaggt agatcaaaag gtgcttctga gaacatgtta gctattgcaa atggtggctt
    15841 gattgggagt gtttcaaaag tagaggagaa ctctactata gtcaaccttc tgacaaatac
    15901 ggaaaatgct gataagattt ctgttaaaat tcaacatggc tctactacaa tttatggaat
    15961 tattattggc tatgacaagg aaaatgacgt tcttaaagtt agccaattaa atagtaatag
    16021 cgatattagt gcgggagata aggtgactac tggtggatta ggaaacttta acgttgctga
    16081 tattcctgtt ggtgaagtgg ttgccacaac gcatagtaca gactatttga cacgagaagt
    16141 aactgttaaa ttgagtgcag atactcataa tgtagatgtg atagaattag tggggaattc
    16201 ataatgagac agttgaagcg agttggagta tttttattgc ttcctttctt tgttctaatt
    16261 gacgcccata ttagccagct tctgggctca tttttccccc atgtacattt ggctagtcat
    16321 tttctttttc tatttctctt atttgagacg atagaagtat cagagtatct ctacctagtc
    16381 tattgttttg ttataggctt ggtttatgat gtttactttt tccatctaat agggattaca
    16441 actctcttat ttatcttatt gggagccttc cttcataaat tgaatagtgt tattttgttg
    16501 aatcgttgga caagaatgct agctatgatt gtactgacat tcctgtttga aatgggtagt
    16561 tatcttttgg cttttatggt agggttgaca gtagatagca tgtcgatttt tatagtctat
    16621 agcttggtac cgacgatgat tttaaatttt ttatggatta ctgtttttca atttattttt
    16681 gaaaaatatt atctataaga acgacatata aatgtaacaa aggcgtaata tttattaggc
    16741 ctttttttgg tatactagta ttgtctttaa aagaaggagt atctacgtaa tatgaagaaa
    16801 aaaatcttag cgtcactttt attaagtaca gtaatggttt ctcaagtagc tgttttaaca
    16861 actgcgcatg cagaaacgac tgatgacaaa attgctgctc aagataataa aattagtaac
    16921 ttaacagcac aacaacaaga agcccaaaaa caagttgacc aaattcagga gcaagtatca
    16981 gctattcaag ctgagcagtc taacttgcaa gctgaaaatg atagattaca agcagaatct
    17041 aagaaactcg agggtgagat tacagaactt tctaaaaaca ttgtttctcg taaccaatcg
    17101 ttggaaaaac aagctcgtag tgctcaaaca aatggagccg taactagcta tatcaatacc
    17161 attgtaaact caaaatcaat tacagaagct atttcacgtg ttgctgcaat gagtgaaatc
    17221 gtatctgcaa acaacaaaat gttagaacaa caaaaggcag ataaaaaagc tatttctgaa
    17281 aaacaagtag caaataatga tgctatcaat actgtaattg ctaatcaaca aaaattggct
    17341 gatgatgctc aagcattgac tacgaaacag gcagaactaa aagctgctga attaagtctt
    17401 gctgctgaga aagcgacagc tgaaggggaa aaagcaagtc tattagagca aaaagcagca
    17461 gctgaggcag aggctcgtgc agctgcggtg gcagaagcag cttataaaga aaaacgagct
    17521 agccaacaac aatcagtact tgcttcagca aacactaact taacagctca agtgcaagca
    17581 gtatctgaat ctgcagcagc acctgtccgt gcaaaagttc gtccaacata cagtacaaac
    17641 gcttcaagtt atccaattgg agaatgtaca tggggagtaa aaacattggc accttgggct
    17701 ggagactact ggggtaatgg agcacagtgg gctacaagtg cagcagcagc aggtttccgt
    17761 acaggttcaa cacctcaagt tggagcaatt gcatgttgga atgatggtgg atatggtcac
    17821 gtagcggttg ttacagctgt tgaatcaaca acacgtatcc aagtatcaga atcaaattat
    17881 gcaggtaatc gtacaattgg aaatcaccgt ggatggttca atccaacaac aacttctgaa
    17941 ggttttgtta catatattta tgcagattaa tttacagagg gactcgaata gagccctctt
    18001 ttcaggtttt accgtgacaa tccctattaa aaattatatc aaaatagctt gaaaatattg
    18061 gaaaagtatg gtaaaatgaa aattgtcgtg tgaacgataa tactcattct tgatgaattg
    18121 tgaagcagtt gcccttgggt cgttttgcga gttgaagtca agaagaggaa aaaaacaaaa
    18181 aggagaaata ctcatggcag taatttcaat gaaacaactt cttgaggctg gtgtacactt
    18241 tggtcaccaa actcgtcgct ggaatcctaa gatggctaag tacatcttta ctgaacgtaa
    18301 cggaatccat gttatcgact tgcaacaaac tgtaaaatac gctgaccaag catacgactt
    18361 catgcgtgat gcagcagcta acgatgcagt tgtattgttc gttggtacta agaaacaagc
    18421 agctgatgca gttgctgaag aagcagtacg ttcaggtcaa tacttcatca accaccgttg
    18481 gttgggtgga actcttacaa actggggaac aatccaaaaa cgtatcgctc gtttgaaaga
    18541 aattaaacgt atggaagaag atggaacttt cgaagttctt cctaagaaag aagttgcact
    18601 tcttaacaaa caacgtgcgc gtcttgaaaa attcttgggc ggtatcgaag atatgcctcg
    18661 tatcccagat gtgatgtacg tagttgaccc acataaagag caaatcgctg ttaaagaagc
    18721 taaaaaattg ggaatcccag ttgtagcgat ggttgacacc aatactgatc cagatgatat
    18781 cgatgtaatc atcccagcta acgatgacgc tatccgtgct gttaaattga tcacagctaa
    18841 attggctgac gctattatcg aaggacgtca aggtgaggat gcagtagcag ttgaagcaga
    18901 atttgcagct tcagaaactc aagcagattc aattgaagaa atcgttgaag ttgtagaagg
    18961 cgacaacgct taatttatac aaatagtaat tacctaggag ggcggggctt agcccggctc
    19021 tcctattttc aaaaaatata ggagaattaa aatggcagaa attacagcta aacttgtaaa
    19081 agagttgcgt gaaaaatctg gtgccggtgt tatggacgct aaaaaagcgc ttgtagaaac
    19141 agacggtgac atcgaaaaag cgattgaatt gcttcgtgaa aaaggtatgg ctaaggcagc
    19201 taagaaagct gaccgtgttg ctgcagaagg tttgactggt gtttatgtta acggtaatgt
    19261 tgcagcagtt attgaagtaa acgctgaaac tgacttcgtt gcaaaaaacg ctcaattcgt
    19321 tgaattggta aatactacag ctaaagtcat tgctgaagga aaacctgcta acaacgaaga
    19381 agctcttgct ttgataatgc cttcaggtga aactcttgaa gctgcatacg tatctgcaac
    19441 agcaactatc ggagagaaaa tctcattccg tcgctttgca ttgattgaaa aaacagacgc
    19501 acaacacttt ggagcatacc aacataacgg tggacgtatc ggtgttattt cagttgttga
    19561 aggtggagac gaagcacttg ctaaacaatt gtcaatgcac atcgcagcga tgaaaccaac
    19621 agttctttct tacaaagaat tggatgagca attcgttaaa gatgagttgg cacaattgaa
    19681 tcacgttatc gaccaagaca acgaaagccg tgcaatggtt aataaaccag ctcttccaca
    19741 cttgaagtat ggatcaaaag ctcaattaac tgatgatgtt attgctcaag ctgaagctga
    19801 catcaaagct gaattggctg cagaaggcaa accagaaaaa atctgggaca aaattattcc
    19861 aggtaaaatg gatcgcttca tgcttgataa cactaaagtt gaccaagctt acacacttct
    19921 tgcacaagtt tacatcatgg atgacagcaa gacagttgaa gcataccttg aatcagttaa
    19981 cgcttcggta gttgagtttg ctcgctttga agttggtgaa ggtatcgaga aagctgcaaa
    20041 cgacttcgaa gctgaagttg cagctacaat ggcagcagcc ttgaataact aataatagaa
    20101 aggaagcaaa ttgcttcctt ttttgtatag ggcttagatt tttcctgaaa ttgttttttc
    20161 cccagtctca ctcgattaga ataattaaaa caaaaagccc tataataagg gctaagtgca
    20221 tttaggagac tatacttcaa attcatagta agcgcgttca taacaaggta tctatcctaa
    20281 ttccccaact tccagtatac tagataaaaa ataattatcg gagtaaaggt attgtactat
    20341 gataattcaa ctaagtgatt taggtcaagt tcaccttgtt tgtggcaaga cagatatgag
    20401 gtagggaata gactcattag cctatgtagt taaaacccac tttgaattgg attctttctc
    20461 cggtcaagtc tttctctttt gtggtgaacg taaagaccgc tttaaagccc tttactggga
    20521 tggtcaagga ttttggctac tatataaacg ctttgagaac ggaaaactga cttggctaag
    20581 tacagaaaag gatgtcaaag ctctcgcacc tgaacaagta gattggctta tgaagggctt
    20641 ttctatcact ccaaaatata gtatattgaa actagaatag tacacctctg cttctaaaac
    20701 attgttagaa atcgatttga ctgtcctgat cgatttatcc tgttcttatt tcattttact
    20761 ataaatctat cagaaagttg tgatttctat tgaaatgagg actttctttt tacactcatc
    20821 tgctttcaaa aagcattcta gtccgtctcc gattaacgat ggactttatc acctccttct
    20881 ccagtccttg tatgacatct tccaaagttc gaaaggcttt attcttaaat ccacgtttac
    20941 gaatctcttt ccacacttgt tcaatggggt tcatctctgg tgtgtatgga ggaataaatg
    21001 caaagccaat attagtcgga atctttaagg tacttgattt atgccatata gcattgtcca
    21061 taacgagtaa aagataatca tctggataag cttgtgaaat ctcctattcc taaagcccct
    21121 ttagcgcata actttggctc agcttctatt atcgctcaca ccatccatca gaagtttaat
    21181 ctgaaggtac ccaattatcg ccaagaagaa gattgggcta ggatgggttt accaatcata
    21241 cgtaaggaaa tctctaattg gcatatcaag acgagtcaat actatttgga gcccctttat
    21301 aacctcttgc gagagagact attgactcag cccttacttc atgcggatga aacttcttat
    21361 agggtgctag agagtgatag tcagctgact tactactgga cttttttgtc tgggaaagct
    21421 gagaaacaag ggattacgct ttaccatcat gtcctaatcg atttgttcat atcttatttc
    21481 aatccattat aaatagtgag aaatatctat cctatcttct agaatgtctt ccaaacg
//
LOCUS       DAVBBO010000036        21460 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ST1
            SAMEA2066453-rid20184263.denovo.036, whole genome shotgun sequence.
ACCESSION   DAVBBO010000036 DAVBBO010000000
VERSION     DAVBBO010000036.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2066453
            Sequence Read Archive: ERR351777
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 21460)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 21460)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980402.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980402.1
            Genome Coverage       :: 176x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:17:33
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,141
            CDSs (total)                      :: 2,104
            Genes (coding)                    :: 1,953
            CDSs (with protein)               :: 1,953
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 16S)
            partial rRNAs                     :: 1 (23S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 151
            CDSs (without protein)            :: 151
            Pseudo Genes (ambiguous residues) :: 0 of 151
            Pseudo Genes (frameshifted)       :: 73 of 151
            Pseudo Genes (incomplete)         :: 76 of 151
            Pseudo Genes (internal stop)      :: 40 of 151
            Pseudo Genes (multiple problems)  :: 32 of 151
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..21460
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2066453-rid20184263.denovo.036"
                     /strain="ST1"
                     /db_xref="taxon:1313"
     gene            66..287
                     /locus_tag="VQU30_001352"
     CDS             66..287
                     /locus_tag="VQU30_001352"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000285460.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HET2447455.1"
                     /translation="MYRRLRDLREDHDLTQKQIAKILSFTNSAYAKIERGEHTLTADV
                     LVTLSNFYDVSTDYLLELTDFPDKIRFRK"
     gene            804..1043
                     /locus_tag="VQU30_001353"
                     /pseudo
     CDS             804..1043
                     /locus_tag="VQU30_001353"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_086558195.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase family protein"
     gene            1187..2416
                     /locus_tag="VQU30_001354"
     CDS             1187..2416
                     /locus_tag="VQU30_001354"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012512582.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsW/RodA/SpoVE family cell cycle protein"
                     /protein_id="HET2447456.1"
                     /translation="MKISKRHLLNYSILIPYLLLSILGLIVVYSTTSAILIEEGKSAL
                     QLVRNQGIFWIVSLILIALIYKLRLDFLRNERLIILVILIEMLLLFLARFIGISVNGA
                     YGWISVAGVTIQPAEYLKIIIIWYLAHRFSKQQEEIATYDFQVLTQNQWLPRAFNDWR
                     FVLLVLIGSLGIFPDLGNATILVLVSLIMYTVSGIAYRWFSTILALVSAASVFVLTTI
                     SLIGVETFSKIPVFGYVAKRFSAFFNPFADRADAGHQLANSYFAMVNGGWFGLGLGNS
                     IEKRGYLPEAHTDFVFSIVIEEFGFVGASLILALLFFMILRIILVGIRAENPFNAMVA
                     LGVGGMMLVQVFVNIGGISGLIPSTGVTFPFLSQGGNSLLVLSVAVAFVLNIDASEKR
                     AKLYRELENQPMNLLLK"
     gene            2436..5132
                     /gene="ppc"
                     /locus_tag="VQU30_001355"
     CDS             2436..5132
                     /gene="ppc"
                     /locus_tag="VQU30_001355"
                     /EC_number="4.1.1.31"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000058210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoenolpyruvate carboxylase"
                     /protein_id="HET2447457.1"
                     /translation="MSLQKLENSSNKSVVQEEVLILTELLEDITKNMLAPETFEKIIQ
                     LKELSTQEDYQGLNRLVTSLSNDEMVYISRYFSILPLLINISEDVDLAYEINHQNNID
                     QDYLGKLSTTIKLVAEKENAVEILEHLNVVPVLTAHPTQVQRKSMLDLTNHIHSLLRK
                     YRDVKLGLINKDKWYNDLRRYIEIIMQTDMIREKKLKVTNEITNAMEYYNSSFLKAVP
                     HLTTEYKRLAQAHGLNLKQAKPITMGMWIGGDRDGNPFVTAKTLKQSALTQCEVIMNY
                     YDKKIYQLYREFSLSTSIVNVSKQVREMARQSKDNSIYREKELYRRALFDIQSKIQAT
                     KTYLIEDEEVGTRYETANDFYKDLIAIRDSLLENKGESLISGDFVELLQAVEIFGFYL
                     ASIDMRQDSSVYEACVAELLKSAGIHSRYSELSEEEKCDLLLKELEEDPRILSATHAE
                     KSELLAKELAIFKTARVLKDKLGDDVIRQTIISHATNLSDMLELAILLKEVGLVDTER
                     ARVQIVPLFETIEDLDHSEETMRKYLSLSLAKKWIDSRNNYQEIMLGYSDSNKDGGYL
                     SSCWTLYKAQQQLTAIGDEFGVKVTFFHGRGGTVGRGGGPTYEAITSQPLKSIKDRIR
                     LTEQGEVIGNKYGNKDAAYYNLEMLVSAAINRMITQKKSDTNTPNRYEAIMDQVVDRS
                     YDIYRDLVFGNEHFYDYFFESSPIKAISSFNIGSRPAARKTITEIGGLRAIPWVFSWS
                     QSRVMFPGWYGVGSSFKEFINKNPENIAILRDMYQNWPFFQSLLSNVDMVLSKSNMNI
                     AFEYAKLCEDEQVKAIYEIILNEWQVTKNVILAIEGHDELLADNPYLKASLDYRMPYF
                     NILNYIQLELIKRQRRGELSSDQERLIHITINGIATGLRNSG"
     misc_binding    5215..5432
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            5545..6549
                     /locus_tag="VQU30_001356"
     CDS             5545..6549
                     /locus_tag="VQU30_001356"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HET2447458.1"
                     /translation="MKNKRLIGIIAALAVLVAGSLIYSSMNKSEAQNNKDEKKITKIG
                     VLQFVSHPSLDLIYKGIQDGLAEEGYKDDQVKIDFMNSEGDQSKVATMSKQLVANGND
                     LVVGIATPAAQGLASATKDLPVIMAAITDPIGANLVKDLKKPGGNVTGVSDHNPAQQQ
                     IELIKALTPNVKTIGALYSSSEDNSKTQVEEFKAYAEKAGLTVETFAVPSTNEIASTV
                     TVMTIKVDAIWVPIDNTIASGFPTVVSSNQSSKKPIYPSATAMVEVGGLASVVIDQHD
                     LGVATGKMIVQVLKGAKPADTPVNVFSTGKSVINKKIAQELGITIPESVLKEAGQVIE
                     "
     gene            6618..7484
                     /locus_tag="VQU30_001357"
     CDS             6618..7484
                     /locus_tag="VQU30_001357"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399556.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HET2447459.1"
                     /translation="MIVSIISQGFVWAILGLGIFMTFRILNFPDMTTEGSFPLGGAVA
                     VTLITKGVNPFLATLVAVGAGCLAGMAAGLLYTKGKIPTLLSGILVMTSCHSIMLLIM
                     GRANLGLLGTKQIQDVLPFDSDLNQLLTGLIFVSIVIALMLFFLDTKLGQAYIATGDN
                     PDMARSFGIHTGRMELMGLVLSNGVIALAGALIAQQEGYADVSRGIGVIVVGLASLII
                     GEVIFKSLSLAERLVTIVVGSIAYQFLVWAVIALGFNTSYLRLYSALILAVCLMIPTF
                     KQTILKGAKLSK"
     gene            7481..8239
                     /locus_tag="VQU30_001358"
     CDS             7481..8239
                     /locus_tag="VQU30_001358"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000125420.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET2447460.1"
                     /translation="MTAIVELKNATKIVKNGFDEEKIILNDVSLEIFERDFITILGGN
                     GAGKSTLFNTIAGTLSLTSGTIRILGEDLTKFSPEKRAKYLSRVFQDPKMGTAPRMTV
                     AENLLIAKFRGEKRGLLPRRLTSYKDEFQATIEKVGNGLEKHLNTPIEFLSGGQRQAL
                     SLLMATLKRPELLLLDEHTAALDPKTSVALMELTDEFVKKDQLTALMITHHMEDALKY
                     GNRLIVMKEGRIIQDLNQEEKAKMKISDYYQLFE"
     gene            8329..10089
                     /gene="dnaG"
                     /locus_tag="VQU30_001359"
     CDS             8329..10089
                     /gene="dnaG"
                     /locus_tag="VQU30_001359"
                     /EC_number="2.7.7.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000227865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA primase"
                     /protein_id="HET2447461.1"
                     /translation="MVDKQVIEEIKNNANIVEVIGDVISLQKAGRNYLGLCPFHGEKT
                     PSFNVVEDKQFYHCFGCGRSGDVFKFIEEYQGVTFMEAVQILGQRVGIEVEKPLYSEQ
                     KPASPHQALYDMHEDAAKFYHAILMTTTMGEEARNYLYQRGLTDEVLKHFWIGLAPPE
                     RNYLYQRLSDQYREEDLLDSGLFYLSDANQFVDTFHNRIMFPLTNDQGKVIAFSGRIW
                     QKTDSQTSKYKNSRSTAIFNKSYELYHMDRAKKSSGKTSEIYLMEGFMDVIAAYRAGI
                     ENAVASMGTALSREHVEHLKRLTKKLVLVYDGDKAGQAAILKALDEIGDMPVQIVSMP
                     DNLDPDEYLQKNGPEDLAYLLTKTRISPIEFYIHQYKPENSENLQAQIEFIEKIAPLI
                     VQEKSIAAQNSYIHILADSLASFDYTQIEQIVNESRQVQRQNRMERISRPTPITMPVT
                     KQLSAIMRAEAHLLYRMMESPLVLNDYRLREDFAFATPEFQVLYDLLGQYGNLPPEVL
                     AEQTEEVERAWYQVLAQDLPAEISPQELSEVEMTRNKALLNQDNMRIKKKVQEASHVG
                     DTDTALEELERLISQKRRME"
     gene            10092..11201
                     /gene="rpoD"
                     /locus_tag="VQU30_001360"
     CDS             10092..11201
                     /gene="rpoD"
                     /locus_tag="VQU30_001360"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000201905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase sigma factor RpoD"
                     /protein_id="HET2447462.1"
                     /translation="MATKQKEVTTFDVQVAEFIRNHKQKGTATDDEINASLVIPFTLD
                     ADGIEDLLQRIQDAGISITDNEGNPSARVLSNEEEPELSDEDLIGSTSAKVNDPVRMY
                     LKEIGVVPLLTNEEEKELALAVEAGDIEAKQRLAEANLRLVVSIAKRYVGRGMQFLDL
                     IQEGNMGLMKAVDKFDYSKGFKFSTYATWWIRQAITRAIADQARTIRIPVHMVETINK
                     LVREQRNLLQELGQDPTPEQIAERMDMTPDKVREILKIAQEPVSLETPIGEEDDSHLG
                     DFIEDEVIENPVDYTTRIVLREQLDEILDTLTDREENVLRLRFGLDDGKMRTLEDVGK
                     VFNVTRERIRQIEAKALRKLRQPSRSKPLRDFIED"
     gene            11215..11544
                     /locus_tag="VQU30_001361"
     CDS             11215..11544
                     /locus_tag="VQU30_001361"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000331934.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-sulfur cluster assembly factor"
                     /protein_id="HET2447463.1"
                     /translation="MAYTEEQIENIKTRILTALEEVIDPELGIDIVNLGLIYEIRFDG
                     DTGQTEIDMTLTTMGCPLADLLTDQIYDAMIEVPEVTDTEVKLVWYPAWTVEKMSRYA
                     RIALGIK"
     gene            11659..12702
                     /gene="cpoA"
                     /locus_tag="VQU30_001362"
     CDS             11659..12702
                     /gene="cpoA"
                     /locus_tag="VQU30_001362"
                     /EC_number="2.4.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398149.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-galactosylglucosyldiacylglycerol synthase"
                     /protein_id="HET2447464.1"
                     /translation="MEKKKLRINMLSSSEKVAGQGVSGAYRELVRLLHRAAKDQLIVT
                     ENLPIEADVTHFHTIDFPYYLSTFQKKRSGRKIGYVHFLPATLEGSLKIPFFLKGIVK
                     RYVFSFYNRMEHLVVVNPMFIEDLVAAGIPREKVTYIPNFVNKEKWHPLPQEEVVRLR
                     TDLGLSDNQFIVVGAGQVQKRKGIDDFIRLAEELPQITFIWAGGFSFGGMTDGYEHYK
                     KIMENPPKNLIFPGIVSPERMRELYALADLFLLPSYNELFPMTILEAASCEAPIMLRD
                     LDLYKVILEGNYRATAGREEMKEAILEYQANPAVLKDLKEKAKNISREYSEEHLLQIW
                     LDFYEKQAALGRK"
     gene            12718..14043
                     /locus_tag="VQU30_001363"
     CDS             12718..14043
                     /locus_tag="VQU30_001363"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399488.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 4 protein"
                     /protein_id="HET2447465.1"
                     /translation="MRIGLFTDTYFPQVSGVATSIRTLKTELEKQGHAVFIFTTTDKD
                     VNRYEDWQIIRIPSVPFFAFKDRRFAYRGFSKALEIAKQYQLDIIHTQTEFSLGLLGI
                     WIARELKIPVIHTYHTQYEDYVHYIAKGILIRPSMVKYLVRGFLHDVDGVICPSEIVR
                     DLLSDYKVKVEKRVIPTGIELAKFERPEIKQENLKELRSKLGIQDGEKTLLSLSRISY
                     EKNIQAVLAAFADVLKEEDKVKLVVAGDGPYLNDLKEQAQNLEIQDSVIFTGMIAPSE
                     TALYYKAADFFISASTSETQGLTYLESLASGTPVIAHGNPYLNNLISDKMFGALYYGE
                     HDLAGAILEALIATPDMNEHTLSEKLYEISAENFGKRVHEFYLDAIISNNFQKDLAKD
                     DTVSQRIFRTVLYLPQQVVAVPVKGSRRMLKASKTQLISMRDYWKDHEE"
     gene            14074..14250
                     /locus_tag="VQU30_001364"
     CDS             14074..14250
                     /locus_tag="VQU30_001364"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399487.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PspC domain-containing protein"
                     /protein_id="HET2447466.1"
                     /translation="MRSGRDKKIAGVCAGVAHYLDMDPTIVQVIWGVLTCCYGAGIVA
                     YIILWIIAPVATDY"
     gene            14309..14443
                     /locus_tag="VQU30_001365"
     CDS             14309..14443
                     /locus_tag="VQU30_001365"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000863859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4044 domain-containing protein"
                     /protein_id="HET2447467.1"
                     /translation="MAFGDNGNRKKTMFEKITLFIVIIMLVASLLGIFATAIGALSNL
                     "
     gene            14507..15817
                     /gene="obgE"
                     /locus_tag="VQU30_001366"
     CDS             14507..15817
                     /gene="obgE"
                     /locus_tag="VQU30_001366"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000061643.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase ObgE"
                     /protein_id="HET2447468.1"
                     /translation="MSMFLDTAKIKVKAGNGGDGMVAFRREKYVPNGGPWGGDGGRGG
                     NVVFVVDEGLRTLMDFRYNRHFKADSGEKGMTKGMHGRGAEDLRVRVPQGTTVRDAET
                     GKVLTDLIEHGQEFIVAHGGRGGRGNIRFATPKNPAPEISENGEPGQERELQLELKIL
                     ADVGLVGFPSVGKSTLLSVITSAKPKIGAYHFTTIVPNLGMVRTQSGESFAVADLPGL
                     IEGASQGVGLGTQFLRHIERTRVILHIIDMSASEGRDPYEDYLAINKELESYNLRLME
                     RPQIIVANKMDMPESQENLEEFKKKLSENYDEFEELPAIFPISGLTKQGLATLLDATA
                     ELLDKTPEFLLYDESDMEEEAYYGFDEEEKAFEISRDDDATWVLSGEKLMKLFNMTNF
                     DRDESVMKFARQLRGMGVDEALRARGAKDGDLVRIGKFEFEFVD"
     gene            15827..15985
                     /locus_tag="VQU30_001367"
     CDS             15827..15985
                     /locus_tag="VQU30_001367"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001841691.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2447469.1"
                     /translation="MGDKPISFRDADGNFVSAADVWNEKKLEELFNRLNPNRALRLAR
                     TKKENPSQ"
     gene            17035..18294
                     /locus_tag="VQU30_001368"
     CDS             17035..18294
                     /locus_tag="VQU30_001368"
                     /EC_number="2.5.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864372.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine
                     1-carboxyvinyltransferase"
                     /protein_id="HET2447470.1"
                     /translation="MRKIVINGGLPLQGEITISGAKNSVVALIPAIILADDVVTLDCV
                     PDISDVASLVEIMELMGATVKRYDDVLEIDPRGVQNIPMPYGKINSLRASYYFYGSLL
                     GRFGEATVGLPGGCDLGPRPIDLHLKAFEAMGATASYEGDNMKLSAKDTGLHGASIYM
                     DTVSVGATINTMIAAVKANGRTIIENAAREPEIIDVATLLNNMGAHIRGAGTNIIIID
                     GVERLHGTRHQVIPDRIEAGTYISLAAAVGKGIRINNVLYEHLEGFIAKLEEMGVRMT
                     VSEDSIFVEEQSNLKAINIKTAPYPGFATDLQQPLTPLLLRANGRGTIVDTIYEKRVN
                     HVFELAKMDADISTTNGHILYTGGRDLRGASVKATDLRAGAALVIAGLMAEGKTEITN
                     IEFILRGYSDIIEKLRNLGADIRLVED"
     gene            18310..18861
                     /locus_tag="VQU30_001369"
     CDS             18310..18861
                     /locus_tag="VQU30_001369"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007521687.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HET2447471.1"
                     /translation="MNIWTKLAMFSFFETDRLYLRPFFFSDSQDFREIASNPENLQFI
                     FPTQASLEESQYALANYFMKSPLGVWAICDQKNQQMIGSIKFEKLDEIKKEAELGYFL
                     RKDAWSQGFMTEVVRKICQLSFEEFGLKQLFIITHLENEASQRVALKSGFSLFRQFKG
                     SDRYTRKMRDYLEFRYVKGEFNE"
     gene            18854..20131
                     /locus_tag="VQU30_001370"
     CDS             18854..20131
                     /locus_tag="VQU30_001370"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016465747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CBS domain-containing protein"
                     /protein_id="HET2447472.1"
                     /translation="MSKHQEILSYLEELPVGKRVSVRSISNHLGVSDGTAYRAIKEAE
                     NRGIVETRPRSGTIRVKSQKVAIDRLTFAEIAEVTSSEVLAGQEGLEREFSKFSIGAM
                     TEQNILSYLHDGGLLIVGDRTRIQLLALENENAVLVTGGFQVHDDVLKLANQKGIPVL
                     RSKHDTFTVATMINKALSNVQIKTDILTVEKLYRPSHEYGFLRETDTVKDYLDLVRKN
                     RSSRFPVINQHQVVVGVVTMRDAGDKSPSTTIDKVMSRSLFLVGLSTNIANVSQRMIA
                     EDFEMVPVVRSNQTLLGVVTRRDVMEKMSRSQVSALPTFSEQIGQKLSYHHDEVVITV
                     EPFMLEKNGVLANGVLAEILTHMTQDLVVNSGRNLIIEQMLIYFLQAVQIDDILRIQA
                     RIIHHTRRSAIIDYDIYHGHQIVSKANVTVKIN"
     gene            20147..21007
                     /locus_tag="VQU30_001371"
     CDS             20147..21007
                     /locus_tag="VQU30_001371"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013903404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionyl aminopeptidase"
                     /protein_id="HET2447473.1"
                     /translation="MITLKSAREIEAMDKAGDFLASIHIGLRDLIKPGVDMWEVEEYV
                     RRRCKEENFLPLQIGVDGAMMDYPYATCCSLNDEVAHAFPRHYILKDGDLLKVDMVLG
                     GPIAKSDLNVSKLNFNNVEQMKKYTQSYSGGLADSCWAYAVGTPSEEVKNLMDVTKEA
                     MYKGIEQAVVGNRIGDIGAAIQEYAESRGYGVVRDLVGHGVGPTMHEEPMVPNYGIAG
                     RGLRLREGMVLTIEPMINTGDWEIDTDMKTGWAHKTIDGGLSCQYEHQFVITKDGPVI
                     LTSQGEEGTY"
     gene            21230..21340
                     /locus_tag="VQU30_001372"
                     /pseudo
     CDS             21230..21340
                     /locus_tag="VQU30_001372"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001818216.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="galactose-6-phosphate isomerase"
BASE COUNT         6560 a         3687 c         4816 g         6397 t
ORIGIN      
        1 ccagttagga cactttgaat gatttcttag ttttatatat tatacttttc tcaggagaaa
       61 gctagatgta cagacgtttg agagatttga gggaagatca cgatttgacc caaaaacaaa
      121 tagctaaaat actttcgttt acaaactcag cttatgctaa aattgaacgg ggtgagcata
      181 cgttaacagc agatgtattg gtaactctct caaactttta cgatgtcagt acagactacc
      241 tattggaatt gacagatttt cctgataaaa ttcgctttag aaaataatct cctcaatttc
      301 atagagtgtg aaaatgagga gattttttat ttgttctttg aaaattaaat agtccaaaat
      361 ggtactttcc tcatttgtgg agcaaatttg aatggctcgc catgataaga gcgattttaa
      421 agccatcaat aaaatagagc gatactttat atgccatgat acaaatgata tacaatgata
      481 cttctgaccg ttcaggctgc catcgtaaaa gagcagcaag tgaaattctt atgatgactt
      541 catcagtcat gccacgttga atgtgtgagt ttgttagaga aacgcaatta atcctcaaaa
      601 ggttccccga accttttgag ttccacagac gcatcacgtg gagtgtgtaa gcttgttgct
      661 aaaagcgtaa aaaccttgga acgaaaggaa taatagactt cctgcgaaac aaaaatacaa
      721 tacaataaaa ctatggatga tgaagcaagt aaacaattaa gcgatagccg tttcaagagc
      781 cttgtaggtg ttcagcgcac gagatgttag ctgtgttaaa aacagcttat caacgcaacg
      841 taaacgcgca aaaggtggac gaaaaaccaa attaagccta gacgatctcc tcatggtaac
      901 tattcaatac atgcgagaat agcgcactta tgaacaaatt gcggctgatt ttggcattca
      961 cgaaagcaac ataattagtc ggaggtcaat ggattgaagc aactcttatt caaaatggtt
     1021 ttacgatttc aaattctgcc ttaattctgt aaaaacagta aaattcgaag gattgtaagg
     1081 taagagtttt tttctttctg aaaaaatggt ataatagcaa tcaaaactag aaaataaaac
     1141 ggaatttgga acagatttgt ctgtatccta gtagagtggt gatactatga agattagtaa
     1201 gaggcactta ttaaattatt ccatcttgat tccctacttg cttttatcta ttttgggctt
     1261 gattgtggtc tattcgacca ccagtgctat tttaattgaa gaaggcaaga gcgccttgca
     1321 gttggttcga aaccaaggaa tcttttggat tgttagtttg atactgattg ccttaattta
     1381 taaattgaga ctagattttt tgagaaatga gcgactaatc attttagtta tattaataga
     1441 aatgctttta ttgttcttgg ctcgttttat tggtatttca gtaaacgggg catacggttg
     1501 gatttcggtt gcaggagtaa ctattcagcc agctgagtac ttaaaaatca ttattatttg
     1561 gtatttagct caccgattct ccaaacagca agaagaaata gctacttatg attttcaagt
     1621 tttgactcaa aatcaatggc ttccccgtgc ttttaatgat tggcgattcg ttctcctagt
     1681 tctgattgga agtttgggaa ttttccctga tttaggaaat gcgactattt tagtcttggt
     1741 ttccttgatt atgtatacag ttagtggaat cgcttatcgc tggttttcaa ccattctggc
     1801 gctcgtatct gccgcttctg tctttgtctt gaccactatc agcctaatcg gtgttgagac
     1861 cttttcaaaa attccagtat ttggctatgt agccaaacgc tttagtgcct tttttaatcc
     1921 ttttgccgat cgtgctgatg caggtcacca gttagctaat tcttattttg ccatggtcaa
     1981 tggtggttgg tttggtctag gtcttggaaa ctcgattgaa aaacgaggtt atttgccaga
     2041 agctcataca gactttgtct tttctatcgt gattgaagaa tttggctttg ttggtgccag
     2101 tcttatttta gctctcttgt ttttcatgat tttgcggatt atcttggtcg gtattcgagc
     2161 ggagaatcct ttcaatgcca tggttgcact cggtgtcgga gggatgatgt tggttcaggt
     2221 atttgtcaat atcggaggga tttcgggctt gattccatct acaggagtaa ccttcccctt
     2281 cttatcccag ggtggaaata gtcttctagt cttatcagtg gcagtagcct ttgtcttaaa
     2341 tattgatgcc agtgaaaaac gcgctaagtt gtaccgagaa ttggaaaatc aaccaatgaa
     2401 ccttctgttg aagtaggata aagaaaggat agtttatgtc tcttcaaaaa ttagaaaatt
     2461 ctagtaataa aagtgttgtg caagaagaag tcttgattct aacagaatta ctggaagata
     2521 ttactaaaaa tatgcttgcc ccagagacct ttgaaaaaat aatacagttg aaagaattat
     2581 caacgcagga agattatcaa ggtctaaacc gtctagtgac tagcttatca aatgatgaaa
     2641 tggtctatat ttcacgctat ttctctatct tgcctctttt gattaatatt tcagaggatg
     2701 tggatttagc ttatgaaatc aatcatcaaa ataatattga tcaggactat ttaggtaaat
     2761 tatctacaac gattaaattg gtagcagaaa aggaaaatgc cgttgagatc ctagaacact
     2821 tgaatgttgt tccggttttg acagcccatc caacacaagt gcaacgcaaa agtatgttgg
     2881 atttaacaaa tcatattcat agtcttttgc gtaaataccg tgatgttaag ttggggttga
     2941 tcaataaaga taaatggtac aatgatttgc gtcgttacat cgaaattatc atgcagacag
     3001 acatgattcg tgagaaaaaa ttaaaagtga ctaacgaaat cacgaatgct atggaatatt
     3061 ataacagctc ctttttgaaa gctgtacctc atttgacgac ggagtataag cgcttagcgc
     3121 aagcgcatgg tctgaattta aaacaggcta aaccaatcac catgggtatg tggataggtg
     3181 gtgaccgtga tggaaatcca tttgttacag caaagacctt gaagcagtct gcactcactc
     3241 aatgtgaagt catcatgaac tactatgata aaaagattta ccaactttat cgtgaatttt
     3301 ctctttcaac tagcattgtc aacgtcagca agcaagtcag agaaatggct cgtcaatcca
     3361 aggataactc gatttaccgc gaaaaagagc tttaccgtcg tgccttgttt gatattcaat
     3421 caaaaattca ggcaactaaa acctatctga ttgaggatga agaagttggg actcgttatg
     3481 aaaccgccaa tgatttctac aaggatttga ttgccattcg agattctcta ctagagaata
     3541 agggcgagtc cttgatttca ggtgattttg tggaattatt gcaggcagta gagatatttg
     3601 gtttttacct agcatcaatt gatatgcgac aagactctag cgtctatgaa gcctgtgtgg
     3661 cagaactctt gaaatcagca ggaattcatt ctcgttatag cgagttgagc gaagaagaaa
     3721 agtgtgacct tcttttgaaa gaattagaag aagatccccg aattctttct gcgactcacg
     3781 cagaaaaatc agaattatta gcaaaagaac tagctatttt taagacggct cgtgttttga
     3841 aagataagtt gggagatgat gtcatccgtc agaccatcat ttcacatgca accaaccttt
     3901 ctgatatgct agaattagct attctgttaa aagaagtagg actggtggat acggaaaggg
     3961 cgcgtgttca gattgttccc ctttttgaaa caattgaaga cttggatcat tcagaggaaa
     4021 caatgagaaa atatctttct cttagccttg ccaaaaaatg gattgactca cgaaataact
     4081 accaagaaat catgcttggc tactctgaca gtaataaaga tggcggttac ttgtcatcat
     4141 gttggaccct ctacaaggct caacaacaat tgactgctat tggagatgaa tttggcgtta
     4201 aggttacctt cttccatggt cgtggtggta ctgtcggtcg tggtggtggg ccaacctatg
     4261 aagccattac atctcaaccg ctcaagtcta tcaaggatcg tatccgtttg acggagcagg
     4321 gtgaagtaat tgggaataaa tacggtaaca aagacgccgc ttactataac cttgaaatgc
     4381 tagtatcggc agctattaac cgtatgatta ctcagaagaa gagcgatacc aataccccaa
     4441 atcgttatga agccattatg gatcaagtag tggaccgtag ttacgatatc taccgtgatt
     4501 tggtctttgg taatgagcat ttctatgatt atttcttcga gtcaagtcca atcaaggcta
     4561 tttcaagttt taatattggt tctcgtccag ccgctcgtaa gactattact gaaatcggtg
     4621 gtttgcgtgc catcccttgg gtattctcat ggtcacagag tcgtgttatg ttccctggat
     4681 ggtacggggt tggttcaagc ttcaaggaat ttatcaataa aaatccagag aatattgcta
     4741 tcttacgaga tatgtaccaa aattggcctt tcttccaatc gcttctttca aatgttgata
     4801 tggttttgtc aaaatcaaat atgaatattg cttttgaata tgctaaactt tgtgaagacg
     4861 agcaagttaa ggccatctat gagattattt taaatgaatg gcaagttact aagaacgtta
     4921 tcttggctat tgaaggacat gacgaactct tagctgacaa tccatatcta aaagctagtc
     4981 tggattaccg tatgccttac tttaatattc tcaactatat tcagttagag ttgattaaac
     5041 gccaacgtcg tggagaattg tccagtgatc aagaacgatt gattcatatc accatcaacg
     5101 gaattgcgac aggattgcgt aattcaggtt gataattttc aagagtgaat gctaaaagtg
     5161 aatatcaaaa aaattctaat agactattga caagtagttt aaaaatgata taatttaacc
     5221 attcagaaaa gtaatcatac aaacttttta gagagtctgt ggtagctgaa aacagataag
     5281 tggcgatgat gaaaattggg ctgaatgcta tttagaattt gaaattataa aaattcggta
     5341 agcacacctt acagtgcatc tcgttattgc gagactgagc gatagggaaa ttccctataa
     5401 ttgaggtggt accgcgcatc gacgtcctca cacaagtttt ttgtgtgagg atttttttga
     5461 tggaggttag tatggaaaga aaacgatggc gtcgcttgtt tagataagtg aaatatgtta
     5521 aaggaaataa aaaggagaaa cagaatgaaa aataaacgtt taattggaat tattgctgca
     5581 ttagcagtct tagtagcagg aagcttgatt tattcttcaa tgaataaatc agaagctcag
     5641 aataataagg atgagaagaa aataaccaag attggtgtgc ttcaatttgt gagccatcca
     5701 tcccttgatt tgatttataa agggatccaa gatggacttg cagaagaagg atataaagat
     5761 gatcaagtta aaattgattt tatgaactca gaaggtgatc aaagtaaggt tgcgacaatg
     5821 agtaaacaat tggttgcaaa tgggaatgac cttgtggttg gtattgcaac accagcagcc
     5881 caagggttgg ctagtgcaac aaaagaccta ccagttatca tggccgctat tacagaccca
     5941 attggtgcta acttggttaa agatttgaaa aaaccaggtg gtaacgttac aggggtatct
     6001 gaccacaatc cagctcaaca acaaattgaa ctcatcaagg ctctgacacc gaatgtgaaa
     6061 acaatcggag ctctttactc aagtagcgaa gacaattcaa aaacacaggt tgaagaattt
     6121 aaggcttatg ctgaaaaagc aggtctgaca gtggaaacat ttgcagttcc ttcaacaaat
     6181 gaaattgcct caactgtcac tgttatgact atcaaggtag atgctatttg ggttccaatt
     6241 gataacacca ttgcatcagg atttccaacg gttgtctcta gcaatcaaag ttctaagaaa
     6301 ccaatttatc ccagtgcgac agctatggta gaagtaggtg gtttggcatc agttgtaatt
     6361 gaccaacatg accttggtgt ggcaacaggt aaaatgattg tgcaagtctt gaaaggtgca
     6421 aaaccagccg ataccccagt caatgtcttt tcaactggta agtcagtcat caataaaaaa
     6481 atagcacaag aactaggtat tactattcct gagtctgttc tcaaagaagc aggacaagtc
     6541 atcgaataaa taaggtaggg aggaggagac tcttcccatt ttttaaaaag atgaatatag
     6601 aaaggattaa ataaaatatg attgtttcca ttatttctca aggatttgtc tgggctattc
     6661 taggtctggg aatctttatg acatttagga ttttaaactt tccagatatg acgacagaag
     6721 gttccttccc tcttggggga gctgttgctg tcactttgat aaccaaaggc gtgaacccat
     6781 ttttagcgac acttgttgct gtaggagcag gttgtttggc tggaatggca gcaggccttc
     6841 tttatacaaa agggaagatc ccaaccttgc tctcagggat tttggtgatg acttcttgtc
     6901 actcaatcat gctcttgatt atgggacgtg cgaatttagg cctgcttgga accaagcaaa
     6961 ttcaggatgt tttgcctttt gattcggatt tgaatcaact cttgacaggt ctcatctttg
     7021 tgagcattgt tattgctctc atgctctttt tcttggacac taaactcgga caagcctata
     7081 ttgctacagg ggataatcct gatatggcta gaagtttcgg gattcatact ggacgcatgg
     7141 agctcatggg cttggtctta tcaaatggtg tgattgccct tgcaggtgcc ctcattgctc
     7201 agcaagaagg ctatgccgat gtgtctcgag ggatcggggt tatcgttgtg gggcttgcaa
     7261 gtttgattat tggagaagtt attttcaaga gtttgagctt ggcagagcgt ttggttacta
     7321 tcgttgtagg ttctatcgct tatcaatttt tagtgtgggc agttatcgca cttggcttta
     7381 atacaagtta ccttcgttta tacagtgcct tgattttagc agtctgcctc atgattccaa
     7441 catttaagca aacaatcttg aaaggagcca agttaagcaa atgacagcaa ttgtagaatt
     7501 aaaaaatgca accaaaattg ttaaaaatgg ctttgatgaa gaaaagatta ttttaaatga
     7561 tgtttcctta gaaatttttg aacgggactt tatcacgatt ttgggcggaa atggtgctgg
     7621 aaaatcaacc ctctttaaca ctatagcagg gaccttatca ctaactagtg gaactatccg
     7681 tattttaggt gaagatctca ctaagttttc acccgagaag cgtgccaagt acctgtctcg
     7741 tgtcttccaa gatccaaaga tggggacagc tccccgtatg acggtcgctg aaaatctttt
     7801 aatcgccaag tttcgtggtg agaagcgtgg attgttacca cgacgcttga ctagctataa
     7861 ggatgaattt caggcaacca ttgaaaaagt aggaaatggt cttgagaaac acttgaatac
     7921 accgattgag ttcttatcag gtggacaaag acaggctttg agtctcttga tggcaacctt
     7981 gaagcgacct gaattactcc tgttagatga gcatactgct gccctggatc caaagactag
     8041 tgttgctttg atggaattga cagatgaatt tgttaagaaa gatcagctaa cagcccttat
     8101 gattactcat catatggaag atgctctcaa atacggcaat cgcttgattg tcatgaaaga
     8161 aggacggatt atccaagatt taaaccaaga agaaaaagca aaaatgaaaa tctctgatta
     8221 ttatcaactc tttgaataaa gtagggaaaa tgagtgaaat ggtttacttt ttttctgaaa
     8281 taaagtatac tatataaagt aaactatgat aacatggagg tattgtgtat ggttgacaaa
     8341 caagtcattg aagaaatcaa aaacaatgcc aacattgtgg aagtcatagg agatgtgatt
     8401 tctttacaaa aggcaggacg gaactatcta gggctctgtc cttttcatgg tgaaaaaaca
     8461 ccttctttca acgttgtaga ggacaagcag ttttaccact gttttggttg tggtcgctca
     8521 ggtgatgtct ttaaattcat cgaggagtac caaggggtta cctttatgga ggctgtccaa
     8581 atcttaggtc agcgtgtcgg gattgaggtt gaaaaaccgc tttatagtga acagaagcca
     8641 gcctcgcctc accaagctct ttatgatatg cacgaagatg cggctaaatt ttaccatgct
     8701 attctcatga caacgactat gggcgaagag gccagaaatt acctttatca gcggggtttg
     8761 acagatgaag tgcttaaaca tttttggatt ggtttagcac ctccagaacg aaactatctc
     8821 tatcaacgtt tgtctgatca gtatcgtgaa gaggatttac tggattcagg cctgttttat
     8881 ctctcggatg ccaatcaatt tgtagacacc tttcacaatc gcattatgtt tcccctgaca
     8941 aatgaccaag gaaaggtcat tgccttctca ggtcgtatct ggcaaaaaac ggattcacaa
     9001 acttctaagt ataaaaacag ccgatcgact gcaattttta acaaaagtta cgaattatat
     9061 catatggata gggcaaaaaa atcttctgga aaaactagtg agatttacct gatggaagga
     9121 ttcatggatg ttattgcagc ctatcgggct ggaatcgaaa atgctgtggc gtcgatggga
     9181 acggccttga gtcgagagca tgttgagcat ctgaaaaggt taaccaagaa attggttctt
     9241 gtttacgatg gagataaggc tgggcaagcc gcgatattga aagcattgga tgaaattggt
     9301 gatatgcctg tgcaaatcgt tagcatgcct gataacttgg atcctgatga gtatctacaa
     9361 aaaaatggtc cagaagactt ggcctatcta ttaacaaaaa ctcgtattag tccgattgag
     9421 ttctacattc atcagtacaa acctgaaaac agtgaaaatc tgcaggctca gattgagttt
     9481 attgaaaaaa tagctccctt gattgttcaa gaaaagtcca tcgctgctca aaacagctat
     9541 attcatattt tagctgacag tctggcgtcc tttgattata cccagattga gcagattgtt
     9601 aatgagagtc gtcaggtgca aaggcagaat cgcatggaaa gaatttccag accgacgcca
     9661 atcaccatgc ctgtcaccaa gcagttatcg gctattatga gggcagaagc ccatctactc
     9721 tatcggatga tggaatcccc tcttgttttg aacgattacc gtttgcgaga agactttgca
     9781 tttgctacac ctgaatttca ggtcttatat gacttgcttg gccagtatgg aaatcttcct
     9841 ccagaagttt tagcagagca gacagaggaa gttgaaagag cttggtacca agttttagct
     9901 caggatttgc ctgctgagat atcgccgcag gaacttagtg aagtagagat gactcgaaac
     9961 aaggctctct tgaatcagga caatatgaga atcaaaaaga aggtgcagga agctagccat
    10021 gtaggagata cagatacagc cctagaagaa ttggaacgtt taatttccca aaagagaaga
    10081 atggagtaat aatggcaaca aaacaaaaag aagtaacaac atttgacgta caggtagcag
    10141 aatttatccg taatcataag caaaaaggga cagcaacaga tgatgaaatc aatgcaagtc
    10201 tggttattcc ttttaccttg gacgctgatg ggattgaaga tctcttgcaa cggattcagg
    10261 atgcagggat ttctatcaca gataacgaag gaaatccaag tgcgcgtgtt cttagcaatg
    10321 aagaagaacc agaactcagc gatgaggact tgattggatc aacttctgct aaggtcaatg
    10381 accctgtccg tatgtacttg aaagaaatag gggtcgttcc tctcttgacc aatgaagagg
    10441 agaaagagtt ggcactggct gttgaagctg gcgatatcga agccaaacaa cgtcttgcgg
    10501 aagccaatct tcgtttggtt gtttccattg ccaaacgcta tgtcggtcgt ggcatgcagt
    10561 tccttgactt gattcaagaa ggaaatatgg gcttgatgaa ggcggttgac aagtttgact
    10621 attctaaagg gttcaagttt tcaacttatg caacttggtg gattcgtcag gctatcactc
    10681 gtgctattgc ggaccaagct cgtaccatcc gtatcccagt tcacatggtt gaaactatca
    10741 ataaattggt tcgtgaacag cggaatctcc ttcaagaatt ggggcaagat ccgacaccag
    10801 aacagattgc tgaacgaatg gatatgacac ctgataaggt tcgtgaaatc ttgaagattg
    10861 cccaagaacc agtatctctt gaaactccta tcggtgaaga ggacgatagc caccttggag
    10921 actttatcga agatgaagtg attgaaaatc cagtggatta tacgactcgt atcgtcttgc
    10981 gtgagcaatt ggatgaaatc ttagatactc ttacagaccg tgaagaaaat gttctgcgtc
    11041 tacgttttgg actagatgat ggaaaaatgc gcacacttga agatgtgggg aaagtcttta
    11101 acgtaactcg tgagcgtatc cgtcagattg aagcaaaggc tttgagaaaa ctacgccaac
    11161 caagtcgcag caaaccgctt cgtgatttta ttgaagacta agagtgagga aaatatggct
    11221 tatacagaag agcaaattga aaacatcaaa acacggattt taacagcctt ggaagaagtc
    11281 atcgaccctg agttgggaat cgatattgtc aatcttggtt tgatctatga gattcgtttt
    11341 gacggtgaca cagggcaaac agagattgac atgactttga caactatggg ttgtccctta
    11401 gcagaccttt tgacagacca gatttatgat gctatgatag aggttccaga agtaacggat
    11461 actgaggtta aattagtctg gtatccagcc tggacagttg aaaaaatgag tcgctatgcc
    11521 cgcattgccc taggcattaa gtaaacatat aaaagcatgt gagagactag aggaaaagcg
    11581 aggaaatttc ccctcttttc ctctagtctc tcctttcttt tgctgatttt attcaaagaa
    11641 aatgatataa tagtagttat ggagaaaaag aaattacgca tcaatatgtt gagttcaagt
    11701 gagaaagtag caggacaggg agtttcaggt gcttaccgtg aattagttcg tcttcttcac
    11761 cgtgctgcca aggaccaatt gattgttaca gaaaatcttc caatcgaggc agatgtgact
    11821 cactttcata cgattgattt tccctattat ttatcaacct tccaaaagaa acgctcaggg
    11881 agaaagattg gctatgtgca tttcttgcca gctacacttg aaggaagttt gaaaattcca
    11941 tttttcttaa agggaattgt gaaacgctat gtattttctt tttacaaccg gatggagcac
    12001 ttggttgtgg tcaatcctat gtttattgag gatttggtag cagctggtat tccacgtgaa
    12061 aaagtgacct atattcctaa ctttgtcaac aaggaaaaat ggcatcctct accacaagaa
    12121 gaggtagtca gactgcgcac agatcttggt cttagtgaca atcagtttat cgtagtaggt
    12181 gctgggcaag ttcagaaacg taaagggatt gatgacttta tccgtctggc tgaggaattg
    12241 cctcagatta cctttatctg ggctggtggc ttctcttttg gtggtatgac agatggttat
    12301 gaacactata agaaaattat ggaaaatccc cctaaaaatt tgatttttcc aggcattgta
    12361 tcgccagagc ggatgcgcga attgtatgct ctagcggatc ttttcttgtt gcctagttac
    12421 aatgagctct ttcctatgac tattttagaa gctgcgagtt gtgaggctcc tattatgttg
    12481 cgtgatttag atctctataa ggtgattttg gagggaaatt atcgggcgac agcgggtaga
    12541 gaagagatga aagaggctat tttggaatat caagcaaatc ctgctgtctt aaaagatctc
    12601 aaagaaaagg ctaagaatat ttccagagag tattctgaag agcatctgtt acaaatctgg
    12661 ttggactttt atgagaaaca agccgcttta gggagaaagt aaaaagtgag gtaatctatg
    12721 cgaattggtt tatttacaga tacctatttt cctcaggttt ctggtgttgc gaccagtatt
    12781 cgaaccttga aaacagaact tgaaaagcag ggacatgctg tttttatctt tacgacgaca
    12841 gataaggatg tcaatcgcta cgaagattgg caaattatcc gcattccaag tgttcctttc
    12901 tttgctttta aggatcgtcg ctttgcctac cgaggtttta gcaaggcact tgaaattgct
    12961 aaacagtatc agctagatat tatccatact cagacagaat tttctcttgg cctgttgggg
    13021 atttggattg cgcgtgaatt gaaaattcca gtcatccata cctatcacac ccagtatgaa
    13081 gactatgtcc attatattgc taaggggata ttgatccggc cgagtatggt caagtatctg
    13141 gttagaggtt tcctgcatga tgtggatggg gttatttgcc ctagtgagat tgtccgtgac
    13201 ttgctatctg attataaggt caaggttgaa aaacgggtca ttcctactgg gattgaatta
    13261 gccaagtttg agcgtccgga aatcaagcag gaaaatttga aagaactgcg tagtaaacta
    13321 gggattcaag atggtgaaaa gacgttgctt agtctttcga gaatctccta tgaaaaaaat
    13381 attcaagcag ttttagcagc ctttgctgat gttctgaaag aggaagacaa ggttaaactg
    13441 gtagtagctg gggatggccc ttatctgaat gacctcaaag agcaagccca gaacctagag
    13501 attcaagact cagtcatctt tacagggatg attgctccta gtgagacggc tctttactat
    13561 aaagcggcgg atttcttcat ttcggcatcg acaagcgaaa cgcaaggttt gacctacttg
    13621 gaaagcttag ccagtggaac acctgtcatt gctcacggaa atccttattt gaacaacctc
    13681 atcagtgata aaatgtttgg agccttgtac tatggagaac atgatttggc tggtgctatt
    13741 ttggaagccc tgattgcaac accagacatg aatgagcata ccttatcaga gaaattgtat
    13801 gagatttcag ctgagaactt tgggaaacga gtgcatgagt tttatctgga tgccattatt
    13861 tcaaataact tccagaaaga tttggctaaa gatgatacgg tcagtcagcg tatctttagg
    13921 acagttttgt atcttccgca acaggtggtt gctgtacctg taaaaggatc tagacgcatg
    13981 ttgaaggctt caaaaacaca gttgatcagt atgagagact attggaaaga ccatgaagaa
    14041 tagaaagagg aacagctatg aaaaaaacaa ttaatgagaa gcggtcgtga taaaaagatt
    14101 gcgggtgttt gtgctggggt ggcccattat ctggatatgg atccgactat cgttcaagtc
    14161 atttggggtg ttcttacttg ctgttacgga gctggaattg tagcttacat tattttatgg
    14221 attatcgcac cagtagcaac tgactattga aaactagctc aattcatgct aagataatag
    14281 aaaatagaat gtaacgaagg agagaaaaat ggcatttgga gataatggaa atcgtaaaaa
    14341 aactatgttt gagaaaataa ccttgtttat cgtgattatc atgctagtag caagtttatt
    14401 gggaattttt gcaactgcaa ttggtgccct cagtaatcta taaaatagat tcaagaaaat
    14461 ttagtgactg ggatttccca gccctttttt aaagtgagaa gaaataatga gtatgttttt
    14521 agatacagct aagattaagg tcaaggctgg taatggtggc gatggtatgg ttgcctttcg
    14581 tcgtgaaaaa tatgtcccta atggaggccc ttggggtggt gatggtggtc gtggaggcaa
    14641 tgtggtcttc gttgtagacg aaggactacg taccttgatg gatttccgct acaatcgtca
    14701 tttcaaggct gattctggtg aaaaagggat gaccaaaggg atgcatggtc gtggtgctga
    14761 ggaccttaga gttcgagtac cacaaggtac gactgttcgt gatgcggaga ctggcaaggt
    14821 tttaacagat ttgattgaac atgggcaaga atttatcgtt gcccacggtg gtcgtggtgg
    14881 acgtggaaat attcgtttcg cgacaccaaa aaatcctgca ccggaaatct ctgaaaatgg
    14941 agaaccaggt caggaacgtg agttacaatt ggaactaaaa atcttggcag atgtcggttt
    15001 agtaggattc ccatctgtag ggaagtcaac acttttaagt gttattacct cagctaagcc
    15061 taaaattggt gcctaccact ttaccactat tgtaccaaat ttaggtatgg ttcgcaccca
    15121 atcaggtgaa tcctttgcag tagccgactt gccaggtttg attgaagggg ctagtcaagg
    15181 tgttggtttg ggaactcagt ttctccgtca catcgagcgt acacgtgtta tccttcacat
    15241 cattgatatg tcagctagcg aaggccgtga tccatatgag gattacctag ctatcaataa
    15301 agagctggag tcttacaatc ttcgcctcat ggagcgtcca cagattattg tagctaataa
    15361 gatggacatg cctgagagtc aggaaaatct tgaagaattt aagaaaaaat tgtctgaaaa
    15421 ttatgatgaa tttgaagagt taccagctat cttcccaatt tctggattga ccaagcaagg
    15481 tctggcaaca cttttagatg ctacagctga attgttagac aagacaccag aatttttgct
    15541 ctacgacgag tccgatatgg aagaagaagc ttactatgga tttgacgaag aagaaaaagc
    15601 ctttgaaatt agtcgtgatg acgatgcgac atgggtactt tctggtgaaa aactcatgaa
    15661 actctttaat atgaccaact ttgatcgtga tgaatctgtc atgaaatttg cccgtcagct
    15721 tcgtggtatg ggggttgatg aagcccttcg tgcgcgtgga gctaaagatg gggatttggt
    15781 ccgcattggt aaatttgagt ttgaatttgt agactaggag actggtatgg gagataaacc
    15841 gatatctttc cgagatgcgg atggtaattt tgtttccgcc gcagacgttt ggaatgaaaa
    15901 gaaattggaa gaactattta atcgtctcaa tccaaatcgt gccttgagat tggcacgaac
    15961 taaaaaggaa aatccatctc agtaaagaag ctaaaaaatc ccgtgcctca tcagacacgg
    16021 gattttgtgg tacgacaggc atgtatagca aactgaatct ggaatagcac agcatatctt
    16081 ctaaaatatt gttataaatt gatttgaatt tcaaaattaa attgtttgat tcttatctca
    16141 atttgttata gtatatctga tgtcaaagtt ctcggcgagt caaatagcga ttcccaagcc
    16201 tgactatcgt gaggtagcgg attaaaatgg tctggggata gaccgtttta agtctgacgc
    16261 tggaaataag aattgtcaga agaagggata gcgaaatcgt ggctctacga acaggaacgt
    16321 gataataagg cgtatatagc ggataagagg gcctcaaact ctaaagtcca aaaaggtagt
    16381 cgtaacctat atgcgtaaat cacgagagta attgaattcg tactaagatt ttctattttc
    16441 actgtaacct tttaacgtcc ttatatcttg tatacacgag gaaagatgta cgacttatcc
    16501 cgtgaggtct atcactataa agagaaaacg acagatagaa gtgatcctga gtcacggtta
    16561 tctttaaaat agattgtctg ataggacggt atgtataaaa cgcttctgtg aactgagaga
    16621 agggggagaa gttcttgcta aaatttagtt gaacagccgt attccgatac ttagataaga
    16681 gatctagtct tagctcctac tcagttttag gggataaaaa aggggaaata gcgattcgag
    16741 aaagattata ctcttcgaaa atctcttcaa atcacgtcaa tatcgccttg ccgtatgtgt
    16801 aggatactga ctacgtcagt tccatctaca acctcaaaac agtgttttga gcaacctgcg
    16861 gctagtttcc tagtttgatc tttgattttc attgagtatt agtaattcag ttactaactc
    16921 gtcaactctg atttatccaa taaaattgaa aaggatggaa aaaaggataa atttatgata
    16981 tactttattt tgaagacctt attagaaatc ttgaaagagt attgaaaact tagaatgaga
    17041 aaaattgtta tcaatggtgg attaccactg caaggtgaaa tcactattag tggtgctaaa
    17101 aatagtgtcg ttgccttaat tccagctatt atcttggctg atgatgtggt gactttggat
    17161 tgcgttccag atatttcgga tgtagccagt cttgtcgaaa tcatggaatt gatgggagct
    17221 actgttaagc gttatgacga tgtattggag attgacccaa gaggtgttca aaatattcca
    17281 atgccttatg gtaaaattaa cagtcttcgt gcatcttact atttttatgg gagcctctta
    17341 ggccgttttg gtgaagcgac agttggtcta ccgggaggat gtgatcttgg tcctcgtccg
    17401 attgacttac accttaaggc gtttgaagct atgggtgcca ctgctagcta cgagggagat
    17461 aacatgaagt tatctgctaa agatacagga cttcatggtg caagtattta catggatacg
    17521 gttagtgtgg gagcaacgat taatacgatg attgctgcgg ttaaagcaaa tggtcgtact
    17581 attattgaaa atgcagcccg tgaacctgag attattgatg tagctactct cttgaataat
    17641 atgggtgccc atatccgtgg ggcaggaact aatatcatca ttattgatgg tgttgaaaga
    17701 ttacatggga cacgtcatca ggtgattcca gaccgtattg aagctggaac atatatatct
    17761 ttagctgctg cagttggtaa aggaattcgt ataaataatg ttctttacga acacctggaa
    17821 gggtttattg ctaagttgga agaaatggga gtgagaatga ctgtatctga ggacagcatt
    17881 tttgtcgagg aacagtctaa tttgaaagca atcaatatta agacagctcc ttacccaggc
    17941 tttgcaactg atttgcaaca accgcttacc cctcttttac taagagcgaa tggtcgtggt
    18001 acaattgtcg atacgattta cgaaaaacgt gtaaatcatg tttttgaact agcaaagatg
    18061 gatgcggata tttcgacaac aaatggtcat attttgtaca cgggtggacg tgatttacgt
    18121 ggggccagtg ttaaagcgac cgacttaaga gctggggctg cactagtcat tgctgggctt
    18181 atggctgaag gtaaaactga aattaccaat atcgagttta tcttacgtgg ttattctgat
    18241 attatcgaaa aattacgtaa tttaggagcg gatattagac ttgttgagga ttaaaccgta
    18301 gaggtgttta tgaatatttg gaccaaatta gcaatgtttt ctttttttga aacggatcgc
    18361 ttgtatttgc gtcctttctt ttttagtgat agtcaggact tccgcgagat agcttcaaat
    18421 ccagaaaatc ttcaatttat tttcccaacg caggcaagtc tggaagaaag tcaatatgca
    18481 ctggccaatt actttatgaa gtcccctttg ggagtgtggg caatttgtga ccagaaaaat
    18541 caacaaatga ttggttctat taaatttgag aagttagatg aaatcaaaaa agaagctgag
    18601 cttggctatt ttttgagaaa agatgcttgg tcgcaaggat ttatgacaga ggttgttaga
    18661 aaaatttgtc agctttcttt tgaggaattt ggcttaaaac aattatttat cattacccac
    18721 cttgaaaatg aagctagcca aagagttgct cttaagtctg gatttagttt gttccgtcag
    18781 tttaagggaa gtgatcgtta cacaagaaaa atgcgggatt atcttgaatt tcggtatgta
    18841 aaaggagagt tcaatgagta agcatcagga aattctaagc tatttggagg aattaccagt
    18901 aggtaaaagg gtcagtgttc gtagcatttc gaatcatcta ggagttagtg atggaacagc
    18961 ctatcgagct attaaagaag ctgaaaaccg tggaattgtg gagacccgtc ctagaagtgg
    19021 aacaattcgt gttaaatccc agaaagttgc tatagataga ttaacgtttg ctgaaattgc
    19081 agaagtgact tcttctgagg ttctggctgg gcaagaaggt ttagagagag aatttagtaa
    19141 gttttcaatt ggtgccatga ctgaacaaaa tatcttgtct taccttcatg atggggggct
    19201 cttgattgtc ggagaccgaa cccgtattca gttgctagcc ttggaaaatg aaaatgcagt
    19261 tctggttaca gggggatttc aggttcatga tgatgtgctt aaactggcca atcaaaaagg
    19321 gattcctgtt ctaagaagta agcatgatac ctttaccgtc gctaccatga tcaataaagc
    19381 cttgtcaaat gtccaaatca agactgatat tctgacagtt gagaaacttt atcgccctag
    19441 tcatgagtat ggttttctga gagagacaga tacagttaaa gattatttgg acttggttcg
    19501 taagaatcgt agcagccgtt tccctgttat caatcaacat caggtcgttg ttggcgttgt
    19561 aaccatgaga gacgctggtg ataaatcacc aagcacgaca attgataagg ttatgtctcg
    19621 tagtctattt ttggttggat tatcgacaaa tattgccaat gtgagtcaac ggatgatcgc
    19681 agaagacttt gaaatggtac cagttgttcg aagcaatcaa actttgcttg gcgttgtgac
    19741 gcgacgagat gtcatggaga agatgagccg ttcccaagtt tcggctctac caactttttc
    19801 tgagcagatt ggacaaaagc tctcttatca ccatgatgaa gtagtcatta cagtggaacc
    19861 ctttatgcta gaaaaaaatg gagttttggc taatggtgta ttggcagaaa ttctgaccca
    19921 catgacccaa gatttagttg ttaatagtgg tcgcaatctc attatcgagc agatgctgat
    19981 ctactttttg caggccgttc agatagatga tatattgcgc attcaggcac ggattattca
    20041 tcatacgaga cggtcagcta taattgatta cgatatttat catggtcacc agattgtttc
    20101 aaaagcaaat gtgactgtta aaattaatta gaaactagga gaaaagatga taacattaaa
    20161 atcagctcgt gaaatcgaag ctatggacaa ggctggtgat tttctagcaa gtattcatat
    20221 aggcttacgt gatttgatta agccaggcgt agatatgtgg gaagttgaag aatatgtccg
    20281 ccgtcgttgt aaagaagaaa atttccttcc acttcagatt ggggttgacg gtgccatgat
    20341 ggactatcct tatgctacct gttgctctct taacgatgaa gtggctcacg ctttccctcg
    20401 tcattatatc ttgaaagatg gtgatttgct caaagttgat atggttttgg gaggtcccat
    20461 tgctaaatct gacctaaatg tctcaaaatt aaacttcaac aatgttgaac aaatgaaaaa
    20521 atacactcag agttattctg gtggtttagc agactcatgt tgggcttatg ctgttggtac
    20581 accgtccgaa gaagtcaaaa acttgatgga tgtaaccaaa gaagctatgt acaagggtat
    20641 tgagcaagct gttgttggaa atcgtatcgg tgatatcggt gcggctattc aagaatacgc
    20701 tgaaagtcgt ggttacggtg tagtgcgtga tttggttggt catggtgttg gcccaactat
    20761 gcacgaagaa ccaatggttc ctaactatgg tattgcaggt cgtggactcc gtcttcgtga
    20821 aggaatggtc ttaaccattg aaccaatgat caatacaggc gattgggaaa ttgatacaga
    20881 tatgaaaact ggttgggcgc ataagaccat tgacggtgga ttgtcatgtc agtatgaaca
    20941 ccaatttgtc attacgaaag atggacctgt tatcttgact agccaaggtg aagaaggaac
    21001 ttattaataa aaagtgaaaa gactactgga agtttattat gaaaaaatcc agtagatctt
    21061 ttcataataa aacgcattgt atcaagtgtt aggggctgat atcatgcgtt tttctgcttt
    21121 taagattttt tccaactctg tttgtaagcg catcataaca aagggtctag gattcagggc
    21181 tctcctccta tatactatta gtaaagtaaa actaagggag gatattttag tgtcgcagtc
    21241 tattgttcct gtagagattc cacaatattg tcgttttgat tctaaaaaga gaaatggaat
    21301 tctgtttaat gttcgtattg ccaatcttaa atttaccttt tttagattag acttcctgcg
    21361 aaacaaaaca tggtatagta gttctatgaa tgatgaagca agtaaacaac taactgatgc
    21421 acgatttaag cgtcttgttg gtgttcaacg cacgactttt
//
LOCUS       DAVBBO010000037        21102 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ST1
            SAMEA2066453-rid20184263.denovo.037, whole genome shotgun sequence.
ACCESSION   DAVBBO010000037 DAVBBO010000000
VERSION     DAVBBO010000037.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2066453
            Sequence Read Archive: ERR351777
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 21102)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 21102)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980402.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980402.1
            Genome Coverage       :: 176x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:17:33
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,141
            CDSs (total)                      :: 2,104
            Genes (coding)                    :: 1,953
            CDSs (with protein)               :: 1,953
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 16S)
            partial rRNAs                     :: 1 (23S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 151
            CDSs (without protein)            :: 151
            Pseudo Genes (ambiguous residues) :: 0 of 151
            Pseudo Genes (frameshifted)       :: 73 of 151
            Pseudo Genes (incomplete)         :: 76 of 151
            Pseudo Genes (internal stop)      :: 40 of 151
            Pseudo Genes (multiple problems)  :: 32 of 151
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..21102
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2066453-rid20184263.denovo.037"
                     /strain="ST1"
                     /db_xref="taxon:1313"
     gene            <1..266
                     /locus_tag="VQU30_001373"
     CDS             <1..266
                     /locus_tag="VQU30_001373"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000040325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="group II intron reverse transcriptase/maturase"
                     /protein_id="HET2447474.1"
                     /translation="SIDERLRTRLRVIIWKQWKKKSRRLWGLLKLGVPKWIADKVSGW
                     GDHYQLVAQKSVLKRAISKPVLEKRGLVSCLDYYLERHALKVS"
     gene            720..1413
                     /locus_tag="VQU30_001374"
                     /pseudo
     CDS             720..1413
                     /locus_tag="VQU30_001374"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809626.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
     gene            1469..1741
                     /locus_tag="VQU30_001375"
     CDS             1469..1741
                     /locus_tag="VQU30_001375"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001818057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol kinase"
                     /protein_id="HET2447475.1"
                     /translation="MFLLFSALVGMLSQLKEVPESVFLQETVEENHLVNVYSVLEVIS
                     TLAFSVFVLLMSYITESFGISISFWLSAICLMIEAILIYIRRDYFK"
     gene            2055..2186
                     /locus_tag="VQU30_001376"
     CDS             2055..2186
                     /locus_tag="VQU30_001376"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000813667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="teichoic acid D-Ala incorporation-associated
                     protein DltX"
                     /protein_id="HET2447476.1"
                     /translation="MKQRKELYLFLGRTALYFLIFLGLLYFFSYLGQGQGSFIYNEF"
     gene            2207..3757
                     /gene="dltA"
                     /locus_tag="VQU30_001377"
     CDS             2207..3757
                     /gene="dltA"
                     /locus_tag="VQU30_001377"
                     /EC_number="6.1.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012972622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--poly(phosphoribitol) ligase subunit
                     DltA"
                     /protein_id="HET2447477.1"
                     /translation="MSNKPIADMIETIEHFAQTQPSYPVYNVLGQEHTYGDLKADSDS
                     LAAVIDQLGLPEKSPVVVFGGQEYEMLATFVALTKSGHAYIPIDSHSALERVSAILEV
                     AEPSLIIAISAFPLEQVSTPMINLAQVQEAFVQGNNYEITHPVKGDDNYYIIFTSGTT
                     GKPKGVQISHDNLLSFTNWMIMDKEFATPSRPQMLAQPPYSFDLSVMYWAPTLALGGT
                     LFTLPSVITQDFKQLFAAIFSLPIAIWTSTPSFADMAMLSEYFNSEKMPGVTHFYFDG
                     EELTVKTAQKLRKRFPNARIINAYGPTEATVALSAVAVTDEMLATLKRLPIGYTKADS
                     PTFIIDEEGNKLPNGEQGEIIVSGPAVSKGYMNNPEKTAEAFFEFEGLPAYHTGDVGT
                     MTDEGLLLYGGRMDFQIKFNGYRIELEDVSQNLNKSRFIESAVAVPRYNKDHKVQNLL
                     AYVILKDGVREQFERDIDITKAIKEDLTDIMMSYMMPSKFLYRDSLPLTPNGKIDIKG
                     LINEVNKR"
     gene            3754..4998
                     /gene="dltB"
                     /locus_tag="VQU30_001378"
     CDS             3754..4998
                     /gene="dltB"
                     /locus_tag="VQU30_001378"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000969717.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-lipoteichoic acid biosynthesis protein
                     DltB"
                     /protein_id="HET2447478.1"
                     /translation="MMEFFQQLPHLEPYGNPQYFVYVIAATLPIFIGLFFKKRFAWYE
                     VLVSLFFIVTMLVGGKTNQLAALGIYLCWEILLLLFYKHYRKSKDGKWVFYLVSFLSL
                     LPIIFVKVQPAINGTQSLLGFLGISYLTFRSVGIIIELRDGVIKDFTLWEFLRFLLFM
                     PTFSSGPIDRFKRFNENYQAIPERDELMDMLDESVRYIMWGFLYKFILAHVLGETLLP
                     PLKNLALQSGGFFNLYALAVMYTFGLELFFDFAGYSMFALAISNLMGIRSPINFNKPF
                     LSRDLKEFWNRWHMSLSFWFRDFVFMRMVMVLTRKKVFKNRNVTSSMAYIVNMLIMGF
                     WHGVTWYYIAYGLFHGLGLVINDAWVRKKKTLNKERKKAGKAALPENRWIQLLGMVVT
                     FHVVMLSFLIFSGFLNNLWFKK"
     gene            5012..5251
                     /gene="dltC"
                     /locus_tag="VQU30_001379"
     CDS             5012..5251
                     /gene="dltC"
                     /locus_tag="VQU30_001379"
                     /EC_number="6.1.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005591431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--poly(phosphoribitol) ligase subunit
                     DltC"
                     /protein_id="HET2447479.1"
                     /translation="MDIKSEVIEIIDELFMEDVSDMMDEDLFDAGVLDSMGTVELIVE
                     IENRFDIRVPVTEFGRDDWNTANKIIAGIVELQNA"
     gene            5244..6512
                     /gene="dltD"
                     /locus_tag="VQU30_001380"
     CDS             5244..6512
                     /gene="dltD"
                     /locus_tag="VQU30_001380"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000919885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-lipoteichoic acid biosynthesis protein
                     DltD"
                     /protein_id="HET2447480.1"
                     /translation="MLKRLWMIFGPVLIAGLLVFLLIFFYPTEMHHNLGAEKRSAVAT
                     TIDSFKERSQKVRALSDPNVRFVPFFGSSEWLRFDGAHPAVLAEKYNRSYRPYLLGQG
                     GAASLNQYFGMQQMLPQLENKQVVYVISPQWFSKNGYDPAAFQQYFNGDQLTSFLKHQ
                     SGDQASQYAATRLLQQFPNVAMKDLVQKLASKEELSTADNEMIELLARFNERQASFFG
                     QFSVRGYVNYDKHVAKYLKILPDQFSYQAIEDVVKADAEKNTSNNEMGMENYFYNEQI
                     KKDLKKLKDSQKSFTYLKSPEYNDLQLVLTQFSKSKVNPIFIIPPVNKKWMDYAGLRE
                     DMYQQTVQKIRYQLESQGFTNIADFSKDGGEPFFMKDTIHLGWLGWLAFDKAVDPFLS
                     NPTPAPTYHLNERFFSKDWATYDGDVKEFQ"
     gene            6667..7107
                     /gene="adcR"
                     /locus_tag="VQU30_001381"
     CDS             6667..7107
                     /gene="adcR"
                     /locus_tag="VQU30_001381"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001249319.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc-dependent transcriptional regulator AdcR"
                     /protein_id="HET2447481.1"
                     /translation="MRQLAKDINAFLNEVILQAENQHEILIGHCTSEVALTNTQEHIL
                     MLLSEESLTNSELARRLNVSQAAVTKAIKSLVKEGMLETSKDSKDARVIFYQLTDLAR
                     PIAEEHHHHHEHTLLTYEQVATQFTPNEQKVIQRFLTALVGEIK"
     gene            7107..7811
                     /locus_tag="VQU30_001382"
     CDS             7107..7811
                     /locus_tag="VQU30_001382"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001269494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter ATP-binding protein"
                     /protein_id="HET2447482.1"
                     /translation="MRYITVEDLSFYYDKEPVLEHINYCVDSGEFVTLTGENGAAKTT
                     LIKASLGILQPRIGKVAISKTNTQGKKLRIAYLPQQIASFNAGFPSTVYEFVKSGRYP
                     RKGWFRRLNTHDEEHIKASLDSVGMWEHRDKRLGSLSGGQKQRAVIARMFASDPDVFI
                     LDEPTTGMDAGSKNEFYELMHHSAHHHGKAVLMITHDPEEVKDYADRNIHLVRNQDSP
                     WRCFNVHENGQEVGHA"
     gene            7804..8610
                     /locus_tag="VQU30_001383"
     CDS             7804..8610
                     /locus_tag="VQU30_001383"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter permease"
                     /protein_id="HET2447483.1"
                     /translation="MLSLLSYDFIQRAFLAVIAMSLFSPVLGTFLILRRQSLMSDTLS
                     HVSLSGVAFGLVLGISPTVSTIAIVLIAAVFLEYLRTVYKSFMEIGTAILMSTGLAVS
                     LIVMSKGRSSSSMSLDQYLFGSIVTISEEQVISLFVIAAVVLILTFLFLRPMYILTFD
                     EDTAFVDGLPVRTMSILFNMVTGVAIALMIPAAGALLVSTIMVLPASIALRLGKNFKS
                     VMLLASAIGFLGMVAGLYISYYAETPASASITIIFVTVFILISLVRRFIK"
     gene            8620..10125
                     /gene="adcA"
                     /locus_tag="VQU30_001384"
     CDS             8620..10125
                     /gene="adcA"
                     /locus_tag="VQU30_001384"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000724057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ABC transporter substrate-binding
                     lipoprotein AdcA"
                     /protein_id="HET2447484.1"
                     /translation="MKKISLLLASLCALFLVACSNQKQADGKLNIVTTFYPVYEFTKQ
                     VAGDTANVELLIGAGTEPHEYEPSAKAVAKIQDADTFVYENENMETWVPKLLDTLDKK
                     KVKTIKATGDMLLLPGGEEEEGDHDHGEEGHHHEFDPHVWLSPVRAIKLVEHIRDSLS
                     ADYPDKKVTFEKNAAAYIEKLQALDKAYAEGLSQAKQKSFVTQHAAFNYLALDYGLKQ
                     VAISGLSPDAEPSAARLAELTEYVKKNKIAYIYFEENASQALANTLSKEAGVKTDVLN
                     PLESLTEEDTKAGENYISVMEKNLKALKQTTDQEGPAIEPEKAEDTKTVQNGYFEDAA
                     VKDRTLSDYAGNWQSVYPFLEDGTFDQVFDYKAKLTGKMTQAEYKAYYTKGYQTDVTK
                     INITDNTMEFVQGGQSKKYTYKYVGKKILTYKKGNRGVRFLFEATDADAGQFKYVQFS
                     DHNVAPVKAEHFHIFFGGTSQEALFEEMDNWPTYYPDNLSGQEIAQEMLAH"
     gene            complement(11245..12018)
                     /locus_tag="VQU30_001385"
     CDS             complement(11245..12018)
                     /locus_tag="VQU30_001385"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000588554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HET2447485.1"
                     /translation="MIKDERVLELIEIIKKKKRIAVKELAEITFSSTSTLRRDLIFLE
                     NQGLIKRKHGYVTLSSMNTIELSHQIREGESTRQKRLIASLAKDFIRSGMCIYLDSST
                     TVYELCPYLSELDNLIIFTNGLHTAQTLSETVKDSSKIFITSGEVKHQSCSVVNYDKE
                     NSLLDHFNIDLAFCSARGIDDQYVYEASLSQAISKKNIIDKAHETILLIDSSKFYKTG
                     FFKINPLSKYTTFISDTLPDQKLLDAVELFDGEWVSDIQ"
     gene            12194..13597
                     /locus_tag="VQU30_001386"
     CDS             12194..13597
                     /locus_tag="VQU30_001386"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000388528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhamnulokinase"
                     /protein_id="HET2447486.1"
                     /translation="MEAVLAIDLGATSGRAIVGYLSENKLVMEEINRFSNLPIRVKGH
                     LSWDIDFLLAKILESIRLANTSYKILSIGIDTWGVDFGLIDNEGKLLSQPVHYRDERT
                     KGVLKEISEMTELEKLYSETGNQIMEINTLFQLFKARQESPDSFYKTNKILLMPDLFN
                     YLLTGKFATEKSIASTTQLFDPRSQNWNQNILKLFELDSSLLPEIVSEGNVLGRIKKE
                     YGLGDIPVVNVCSHDTASAIVSVPKTEGSLFISSGTWSLVGVELTSPILTTESFSYGF
                     TNEVGKDGVITFLKNCTGLWIIEELRRSFERRGKAYSFDDIRTMVEKEKENLPLIDTE
                     STEFATESDMHKTLTEYLAYHHETREWTDGQLFKIVYESLAETYRKAIELLEELTHKV
                     YKRIYVIGGGARASYFNQMIADRTGKEVLTGLTEATAVGNIVVQLIAMGQLKGMEEAH
                     HVIEEFLQLESYYSQKN"
     gene            13712..14350
                     /locus_tag="VQU30_001387"
     CDS             13712..14350
                     /locus_tag="VQU30_001387"
                     /EC_number="4.1.2.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001286141.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-fuculose-phosphate aldolase"
                     /protein_id="HET2447487.1"
                     /translation="MSDVKQELIKYGKKLVETDLTKGTGGNLSVFDREKQLMAITPSG
                     IDFFEIKESDIVVMDINGNVVEGERLPSSEWYMHLIQYQTRDDIDAIIHAHTTYATVL
                     ACLREPLPASHYMIAVAGKDVRVAEYATYGTKELAVNAAKAMEGRRAVLLANHGILAG
                     AQNLLNAFNIVEEVEYCAKIYCLAKNFGEPVVLPDEEMELMAEKFKTYGQRK"
     gene            14362..14802
                     /locus_tag="VQU30_001388"
     CDS             14362..14802
                     /locus_tag="VQU30_001388"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000912112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RbsD/FucU family protein"
                     /protein_id="HET2447488.1"
                     /translation="MLKHIPKNISPDLLKTLMEMGHGDEIVLADANYPSASCANKLIR
                     CDGVNIPELLDSILYLMPLDSYVDSSIQFMNVVSGDDIPKIWGTYRQMIEGHGTDLKT
                     ITYLRREDFYERSKKAYAIVATGETSLYANIILKKGVVVERENV"
     gene            14795..15226
                     /locus_tag="VQU30_001389"
     CDS             14795..15226
                     /locus_tag="VQU30_001389"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000483177.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HET2447489.1"
                     /translation="MFNRGILVASHGDFASGALMTAEMFVGETTNDRVRTLGLMPGEN
                     IVEFEHYFKNQVDELLDSNQEVIVLTDLIGGSPNNVALSRFLNLDSVDIVTGFNIPLL
                     VELISNYDSKINLEEIVHNAQNSLFNVKQQLNVEEEENLCL"
     gene            15217..15687
                     /locus_tag="VQU30_001390"
     CDS             15217..15687
                     /locus_tag="VQU30_001390"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000020992.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HET2447490.1"
                     /translation="MSIEFVRIDDRLVHGQVVTTWLKKYDIEQVIIVNDRISEDKTRQ
                     SILKISAPVGLKIVFFSVKRFVEVLNSVPIKKRTMLIYTNPKDVYDSIEGNLKLEYLN
                     VGQMSKTEENEKVTGGVALGEEDKYYFKKIVDKGTRVEIQMVPNDKVTMLEKFL"
     gene            15712..16485
                     /locus_tag="VQU30_001391"
     CDS             15712..16485
                     /locus_tag="VQU30_001391"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000899624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS
                     mannose/fructose/sorbose/N-acetylgalactosamine transporter
                     subunit IIC"
                     /protein_id="HET2447491.1"
                     /translation="MLFTQALLVTLVGIIATIDYNGPLFMIHRPLVTSAMVGLVLGDF
                     TQGVLIGSALELTWLGVTGIGGYTPPDTISGAIIGTAFGILSGQGETAGIAIAVPIAV
                     ATQQLDVLAKTLDVYFVKKADNDAKNGDYSKIGFYHYSSLVLITLFKIVPIFLAIMLG
                     GEYVADLFAKVPPIVMQGLNSAGALLPSIGFGMLLNMMLKKNMWVFLLIGFICSVYGG
                     MSTIGISLVGIAVAYFYDMIGSKPQETTSSSDVEEDLDL"
     gene            16482..17282
                     /locus_tag="VQU30_001392"
     CDS             16482..17282
                     /locus_tag="VQU30_001392"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002935197.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose/fructose/sorbose transporter family
                     subunit IID"
                     /protein_id="HET2447492.1"
                     /translation="MMNNKVTKVELKKVFKRSFMYGSSWNYERMQNLGFLYTILPVLK
                     KLYPDKDSASPAMKRHLEFFNTHQTAAPFILGVTSAMEEQEGNEGAASITGIKVGLMG
                     PLAGLGDSLFWLTLVPICFSIGASYSKDGGALGIFIALILFNIINIPVKYFGLKYGYT
                     KGSSLIQENNTKGTLNRVTSMATALGLVLVGGLIPSMVGINFGLEFKQGELVISVQEM
                     ITKLIPGFIPMALTLLMCKLIRKGKNPVVLIFSVMAIGVILVVLGILK"
     gene            17341..19635
                     /locus_tag="VQU30_001393"
     CDS             17341..19635
                     /locus_tag="VQU30_001393"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000780629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 95 protein"
                     /protein_id="HET2447493.1"
                     /translation="MKLWYKKAASNWNEALPIGNGHLGGMIYGSATKECIQLNDETIW
                     YRGKSDRNNPDSLLHLKKIREYLLDGEIQKAEELIKLTMFATPRDQSHYELLGELYIE
                     HIDIQSCALSLYERELDLDTAISNVVFEPNSCNLQIKREYFTSFNKNILCCRIVSSVQ
                     NTLNLNINLGRNKRFNDEVSKLDSSTILMSASAGGRKGVQFKVVCHSKVTDGEVSVLG
                     ETIVIRNATEVFLYLKSMTDYWGNIDISSLQGEFSSIDYFTEKDEHVKKYQEQFNRVD
                     FKLDYSKDCLSIPTNLLLENTKKYSNYLTNLLFHYGRYLLISSSQPNGLPVNLQGIWC
                     DELNPIWGSKYTININTQMNYWMVGPCDLPEVEYPLFDMLERMREPGRLTAKKMYGAR
                     GFTAHHNTDGFGDTAPQSHAMGAAIWVLTIPWLCTHIWEHYLYFQDERILTEHFEMIK
                     EAFLFFEDYLFEVDGYLMTGPSVSPENKYRLKNGIEGNACLSSTIDNQILRYFCDSCI
                     GIAKQLGDNSDFISRVKELKKKLPKTKIGSNGQIQEWLEDYEEVEPGHRHISPLFGLY
                     PYNEIDIHKTPELAEAAKITINRRLSNANFLSSQEREQAINNWLVSGLHASTQTGWSA
                     AWLIHFFARLYQGEPAYNQINGLLNNATLGNLFLDHPPFQIDGNLGLVSGICELLVQS
                     HHNWLSLIPALPSAWSEGEVKGFRVRGGYKVSFAWKNGDITFLKLEGGNKDQKVRVRI
                     YGKNTDVQNIELVFNSEKIIELNF"
     gene            19645..>21102
                     /locus_tag="VQU30_001394"
     CDS             19645..>21102
                     /locus_tag="VQU30_001394"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001031112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2447494.1"
                     /translation="MNKEKIKRKLITILFVCIGMLCFGLLAGVKADNRVQMRTTINNE
                     SPLLLSPLYGNDNGNGLWWGNTLKGAWEAIPEDVKPYAAIELHPAKVCKPTSCIPRDT
                     KELREWYVKMLEEAQSLNIPVFLVIMSAGERNTVPPEWLDEQFQKYSVLKGVLNIENY
                     WIYNNQLAPHSAKYLEVCAKYGAHFIWHDHEKWFWETIMNDPTFFEASQKYHKNLVLA
                     TKNTPIRDDAGTDSIVSGFWLSGLCDNWGSSTDTWKWWEKHYTNTFETGRARDMRSYA
                     SEPESMIAMEMMNVYTGGGTVYNFECAAYTFMTNDVPTPAFTKGIIPFFRHAIQNPAP
                     SKEEVVNRTKAVFWNGEGRISSLNGFYQGLYSNDETMPLYNNGRYHILPVIHEKIDKE
                     KISSIFPNAKILTKNSEELSSKVNYLNSLYPKLYEGDGYAQRVGNSWYIYNSNANINK
                     NQQVMLPMYTNNTKSLSLDLTPHTYAVVKENPNNLH"
BASE COUNT         6542 a         3448 c         4467 g         6645 t
ORIGIN      
        1 ccagcataga tgagcgcttg cgtactcgcc tacgagtgat tatctggaag caatggaaga
       61 agaaatcgag acgattatgg ggattgctta agttaggagt tcctaaatgg atagcagata
      121 aggtatctgg ctggggcgac cattatcaat tagtagctca gaagtcggta cttaaacgtg
      181 ctatatcaaa accagtcctg gaaaaacgtg gactggtttc gtgtttggat tattaccttg
      241 aacgacatgc gttaaaagtt agttgaaccg ccgtatgccg aacggcacgt acggtggtgt
      301 gagaggggct agagattatc ctctactcga ttaactcccc tgaaatttgt tttaattatg
      361 caaatttcac gtatttttga tgctgagacg acgatcctgg gaacttttca gatatttttt
      421 tgactatcta aaatctatca ttagaaaagc ttagagcgcc aaaggatttg agcgtttttc
      481 tgatttttaa gactttttcc cagtctcttt ttcgattgaa gatgtaatta ttctactaac
      541 taacttctta gtactagcca acaacgataa tcataattcc tcctaaaatt aggaataata
      601 aaggcaatag tttttgtttt ttcatgtaaa aaacctcact tttgttttct gctattttat
      661 gctaaaatat taaaaatcaa atttaattcc aaagtttgta actaaagggg gagcgctaca
      721 tgtctaattc atttgtcaag ttgttagtct ctcaattatt tgcaaattta gcagatattt
      781 tctttagagt aacaatcatt gctaacatat acattatttc aaaatcagta attgccacat
      841 cactagttcc tatcttaata ggaatatcct cttttgttgc gagtctttta gttccgttgg
      901 ttactaaaag gttagcgcta aatagggttt tatctttatc tcaatttgga aagactatat
      961 tattggcgat actggtagga atgtttaccg taatgcaatc cgtagcgcct ttggtgacct
     1021 atctatttgt tgttgcaatt tccatactag atggttttgc agcacccgtt tcctatgcta
     1081 ttgtgccacg ctatgcgacc gatttgggta aggctaattc agccttatca atgactggtg
     1141 aagctgttca attgataggt tggggattag gtggactctt gtttgcaaca attggtctgt
     1201 tacctaccac gtttatcatt ttagtcttgt atatcatttc tagctttctg atgttatttc
     1261 ttcctaacgc tgaagtggag gtgttagagt cagaaactaa tcttgaaatt ttgctcaaag
     1321 gttggaagtt agttgctaga aatcctagat taagactttt tgtatcagca aatttattgg
     1381 aaattttttc aaatacgatt tgggtttctt ccattttgta gctatggcaa tagtgacact
     1441 gactattcta tattttccaa acgcacagat gtttttatta ttttcagctt tagttggtat
     1501 gttatcgcaa ctaaaagaag ttcctgaaag tgtatttctt caggaaacag tagaggaaaa
     1561 tcatttagtt aatgtctatt ccgttcttga agtgatttct acattagcat tttcagtatt
     1621 tgttttgcta atgagctata ttactgagag ttttggtatt agcatcagtt tttggctatc
     1681 agccatttgt ctgatgatag aagctatttt aatttatatc agacgagatt attttaaatg
     1741 agagagtggt taaaaagtct ttaaaaatca gaaaagcgca tagtatcagg tgttgaaaaa
     1801 acttgatatt gtgtgtttta ttatgggaag atttacttca ttgtctcctg aaatggagtt
     1861 ttgaagcagg atcactctat ttgaaaatat acatagaaaa actgtataat ccttaaaata
     1921 agctgaaatc tattggaaac atacggtaaa caattgaaaa ggtactatat aaagtggtac
     1981 aatggtagaa aaataagcta gtaagaatca ctcttatttt agcgaaaaat tacagaaatg
     2041 aatggttttt cttgatgaaa cagagaaaag aattgtacct ctttcttggt cggacagcct
     2101 tgtattttct tatctttcta gggctgcttt acttctttag ctatcttggt cagggtcaag
     2161 gaagctttat ctataatgaa ttttaacttg aaggagaatc cctattgtgt caaataaacc
     2221 aatagcagat atgattgaaa ccattgagca ttttgctcag acacagccta gctatcctgt
     2281 ctataatgtt ttggggcagg aacacactta tggcgattta aaggctgatt cggatagttt
     2341 ggctgcagtc attgaccaac taggcttgcc tgagaagtct cctgtggttg tttttggtgg
     2401 ccaagaatat gaaatgttgg caacctttgt agcgctgact aagtcaggtc atgcctacat
     2461 tccaattgat agccattcgg ccttggagcg agtttcagct attttagaag tagcagagcc
     2521 aagcttgatt attgccattt cagcctttcc cttggagcag gtttctacac caatgataaa
     2581 tctagctcag gttcaagaag cctttgttca agggaataac tatgaaatca cgcatccagt
     2641 caagggagat gataattact acattatctt tacttctggt acgactggta agcctaaggg
     2701 agtgcagatt tcacatgata atctcctcag ctttacaaac tggatgatta tggataagga
     2761 atttgcgaca ccgagtcgtc cgcaaatgct ggcacagcca ccttattctt ttgacttgtc
     2821 tgtcatgtat tgggcaccga ccttggcact tggtggtacg cttttcactc ttccttcagt
     2881 catcactcag gactttaagc aactctttgc ggctatcttt tcattgccaa tcgctatctg
     2941 gacatcaaca ccatcctttg cagatatggc catgttgtct gaatacttca acagtgagaa
     3001 aatgcctgga gtcacgcatt tctactttga tggtgaagaa ttgacggtca aaacagctca
     3061 aaaactgcgc aagcgtttcc caaatgcccg tatcatcaat gcttacggcc caacagaagc
     3121 gacagtagct ctgtcagcag ttgccgtgac agacgagatg ttagcgactc tcaaacgcct
     3181 accaatcggc tataccaagg ctgattctcc aacctttatc attgacgagg aaggaaataa
     3241 actgccaaat ggcgaacagg gagaaatcat tgtttctggg ccagctgttt caaaaggtta
     3301 tatgaacaat cctgaaaaaa cagcagaagc cttctttgag tttgaaggtc tgccagccta
     3361 tcacacaggc gatgtgggaa ccatgacaga tgagggcttg cttctctacg gcggacgcat
     3421 ggacttccag attaagttta acggttaccg cattgagtta gaagatgtct ctcaaaacct
     3481 caacaagtct cgctttatcg aatctgctgt cgcagtaccg cgctataaca aggaccacaa
     3541 ggtacaaaat ctattggctt atgtcatctt aaaagacggt gttcgtgagc agtttgagcg
     3601 agatatcgat attaccaagg ccatcaagga agacctgaca gacatcatga tgtcctatat
     3661 gatgccatct aaattccttt accgagacag tttgccactg actccaaatg gaaagattga
     3721 catcaaagga ttgattaacg aggtgaataa gagatgatgg agttttttca acagcttcct
     3781 catttagagc catatggcaa tcctcagtat tttgtttatg tgattgctgc aaccttgccc
     3841 atctttatag gtctcttttt caagaaacgc tttgcctggt atgaagtgtt ggtaagtctc
     3901 ttctttattg tcaccatgtt ggtgggtgga aagaccaatc aactagctgc cttgggtatt
     3961 tacctttgct gggaaatatt gctcctgctt ttctacaagc attatcgaaa aagcaaggat
     4021 ggcaagtggg tcttctactt agttagtttt ctgtccctac ttccgattat ctttgtcaag
     4081 gtgcaaccag ctatcaatgg aacgcagtct ttgcttgggt tcttgggaat ttcttatctt
     4141 acctttcgtt cggttgggat tatcatcgag ctgagagatg gagtgattaa ggattttacc
     4201 ctctgggaat tcctccgttt ccttctcttc atgccaactt tctcgagtgg tccaatcgat
     4261 cgctttaagc gatttaatga aaattatcag gctattcctg agcgagatga gttgatggat
     4321 atgctggatg aatctgtccg ctatatcatg tggggctttt tgtataagtt tatcctagct
     4381 catgttttag gagagacctt actacctcct ctgaagaatt tagccttgca gtcaggtggc
     4441 ttctttaatc tctatgcctt ggcagttatg tatacttttg gtctggagct cttctttgac
     4501 tttgcaggtt attctatgtt tgctttggcc atctcaaact tgatgggaat ccgtagccct
     4561 atcaacttta acaagccctt tttatcaagg gatttaaagg agttttggaa tcgctggcat
     4621 atgagtctgt ccttctggtt ccgtgacttt gtctttatgc gaatggtgat ggtgttaacc
     4681 agaaagaaag tctttaaaaa tcgtaatgta acctcaagca tggcctacat tgtaaatatg
     4741 ctgattatgg gattttggca tggtgtgacc tggtactata tcgcctatgg actctttcat
     4801 ggactaggct tggtcatcaa tgatgcctgg gttcgcaaga aaaaaacact caataaggaa
     4861 cggaaaaaag cagggaaggc tgccctacct gagaatcgct ggattcagtt gcttggcatg
     4921 gttgtcactt tccatgttgt catgttgtca ttcttaatct tttctggatt cttgaataat
     4981 ctatggttta aaaaataaaa ggaaataaaa tatggatatc aaatcagaag ttatcgaaat
     5041 tattgatgag ttgtttatgg aagatgtttc tgacatgatg gatgaagatc tttttgatgc
     5101 aggtgtcttg gatagtatgg gaacggttga gttgattgtg gagattgaga accgttttga
     5161 cattcgtgtc cctgtaacag agtttggtcg tgacgactgg aatacagcta ataaaatcat
     5221 agctggtatt gtggagctac aaaatgctta aacgcttatg gatgatcttc ggaccggtct
     5281 tgatcgctgg tttgttggtt tttctgctca ttttctttta tcctactgag atgcatcata
     5341 atctaggagc tgaaaagcgt tcagcagtgg ctactactat cgatagtttt aaggagcgaa
     5401 gtcaaaaagt cagagcacta tctgatccaa atgtgcgttt tgttcccttc tttggctcta
     5461 gtgaatggct tcgttttgac ggtgctcatc ctgcggtatt agctgagaaa tacaatcgtt
     5521 cctaccgtcc ttatctttta ggacaggggg gagctgcatc gcttaaccaa tattttggaa
     5581 tgcaacagat gttaccacag ctggagaata aacaagttgt gtatgttatc tcacctcagt
     5641 ggttcagtaa aaatggctat gatccagcag ccttccagca gtattttaat ggagaccagt
     5701 tgactagttt tctgaaacat caatctgggg atcaggctag tcaatatgca gcgactcgct
     5761 tactgcaaca gttcccaaac gtagctatga aggacctggt tcagaagttg gcaagtaaag
     5821 aagaattgtc gacagcagac aatgaaatga ttgaattatt ggctcgtttt aatgaacgcc
     5881 aagcttcctt ttttggtcag ttttcggtta gaggctatgt taactacgat aagcatgtag
     5941 ctaagtattt aaaaatcttg ccagaccagt tttcttatca ggcaatagaa gatgttgtca
     6001 aagcagatgc tgaaaaaaat acttccaata atgagatggg aatggaaaat tatttctata
     6061 atgagcagat caagaaggat ttgaagaaat taaaggattc tcagaaaagc tttacctatc
     6121 tcaagtcgcc agagtataat gacttgcagt tggttttaac acagttttct aaatctaagg
     6181 taaacccgat ttttatcatt ccacctgtta ataaaaaatg gatggactat gctggtctac
     6241 gagaggatat gtaccaacaa acggtgcaga agattcgcta ccagttagaa agtcaaggtt
     6301 ttaccaatat agcagatttt tctaaggacg gcggggagcc tttctttatg aaggacacca
     6361 ttcaccttgg ttggttgggt tggttggctt ttgacaaggc agttgatcct ttcctatcca
     6421 atcccacacc agctccgact taccatctga atgagcgctt tttcagcaaa gattgggcga
     6481 cttatgatgg agatgtcaaa gaatttcaat agataatata atatagaaga gttcaagaat
     6541 gaaactagtt ttcacgtttt ttcttgactc tttttttgct tgtgatataa ttaactggta
     6601 aacaaaatgt caaagaatag tatttttctc ttaaaaaaga gaagtctaaa aggaaaggag
     6661 tcagatatga gacagctagc aaaggatatc aatgcttttt tgaatgaggt gattttgcag
     6721 gcggaaaatc agcatgaaat cctaataggt cattgcacta gcgaggtggc cctgaccaat
     6781 actcaggagc atatccttat gctcttgtca gaggaatctt taacaaattc agaattggcc
     6841 cgtcgtctca atgtcagtca ggcggcagtt accaaggcca ttaagtcttt ggtcaaggaa
     6901 gggatgttgg aaacatctaa agattctaaa gatgcgcgtg tgatttttta tcagttgact
     6961 gacttggctc gtccaatcgc tgaggagcac caccatcacc atgagcatac acttttaacc
     7021 tatgaacaag tggcgactca gtttactcca aatgaacaaa aagtgattca gcggtttttg
     7081 actgctttag taggagaaat caaataatga gatatattac ggtagaggat ttgtccttct
     7141 attatgataa ggaacctgtt cttgaacata tcaattattg tgttgatagt ggggaatttg
     7201 ttaccttgac tggggaaaat ggagcggcta agacgacgct catcaaggcc agtcttggaa
     7261 ttctgcaacc acgcattgga aaggtggcta tttcaaagac aaatacgcaa ggtaagaaat
     7321 tgagaatagc ctatcttcct caacaaattg ccagttttaa tgctggtttt ccaagtacgg
     7381 tctatgaatt tgtcaagtcg ggtcgctatc cgagaaaagg ctggttccgt cgtttgaata
     7441 ctcatgatga ggagcatatc aaggctagtc tggactcagt tggcatgtgg gaacatcgag
     7501 acaaacgctt ggggtctcta tctgggggac aaaagcagcg agcggtaatt gcgcgtatgt
     7561 ttgcttctga ccctgatgtg tttatcctag acgagccgac aacggggatg gatgcaggaa
     7621 gtaaaaatga attttacgaa ctcatgcacc acagcgccca tcatcatggc aaggctgttt
     7681 tgatgattac ccatgaccct gaagaagtta aggattatgc ggatcgcaat attcatctag
     7741 tccgtaacca agactcgcca tggcgttgtt tcaacgttca tgagaatggg caggaggtgg
     7801 gccatgctta gtttattatc ttacgacttt atacaacgcg cctttttggc ggttattgct
     7861 atgagtcttt tctcaccggt attgggaacc ttcctcatct tgcgtcgtca gagtttgatg
     7921 agtgataccc ttagccacgt ctcactttca ggtgtagcct ttggtctggt tttggggatt
     7981 tctccaactg tttctactat tgccattgtc ttgattgcgg cggtctttct ggagtatctc
     8041 cgtacggttt acaagagctt tatggaaatc gggacagcta tcctcatgtc aacaggtttg
     8101 gctgtttctc tgattgtcat gagcaagggt agaagctcga gttcaatgag tttggaccaa
     8161 tatctctttg gttcgatcgt gactatcagt gaagaacagg tcatttccct ctttgtcatt
     8221 gcggcggttg ttttgatttt gacctttctc tttcttcgtc ctatgtatat cttaactttt
     8281 gacgaagata cggcctttgt ggatggcttg ccagttcgta ccatgtccat tctttttaac
     8341 atggtgacag gggtggctat tgcccttatg attcctgcag caggagctct tctggtatcg
     8401 accattatgg tcttgccagc tagtattgcc ctgcgtctgg ggaaaaactt taaatcggtt
     8461 atgctgcttg ccagtgcgat tggctttttg ggaatggtag caggacttta catttcctac
     8521 tatgcagaaa cacctgcaag tgcaagtatt accattattt ttgtaactgt ctttatacta
     8581 atcagtttag taagacgttt tatcaaatag gagacgaacg tgaaaaaaat tagcttatta
     8641 ctagccagtc tatgtgcctt gtttttagtg gcttgttcca atcaaaaaca ggcagatggt
     8701 aaactcaata tcgtgacaac cttttaccct gtctatgaat ttaccaagca agtcgcagga
     8761 gatacggcta atgtagaact cctaatcggt gctgggacag aacctcatga atacgaacca
     8821 tctgccaagg cagttgccaa aatccaagat gcagatacct tcgtttatga aaatgaaaac
     8881 atggaaacat gggtacctaa attgctagat accttggata agaaaaaagt gaaaaccatc
     8941 aaggcgacag gcgatatgtt gctcttgcca ggtggcgagg aagaagaggg agaccatgac
     9001 catggagaag aaggtcatca ccatgagttt gacccccatg tttggttatc accagttcgt
     9061 gccattaaac tagtagagca catccgcgac agcttgtcag cagattatcc tgataaaaaa
     9121 gtgacctttg agaagaatgc agctgcctat atcgaaaaat tgcaagcctt ggataaggct
     9181 tacgcagaag gcttgtctca agcaaaacaa aagagctttg tgactcaaca cgcagccttt
     9241 aactatcttg ccttggacta tggactcaaa caagtcgcaa tctcaggact ttctccagat
     9301 gcagagccat cagctgctcg cttggcagaa ttgacagagt atgtcaagaa aaataaaatc
     9361 gcctatatct attttgaaga aaatgcctca caagcccttg ctaacacact ttcaaaagaa
     9421 gcaggtgtca aaactgatgt cctcaatcct ttagaaagtc tgacagaaga ggacaccaag
     9481 gctggagaaa actacatttc cgtgatggag aaaaacctca aggctttgaa acaaacaaca
     9541 gaccaagaag gcccagcaat cgaacctgaa aaggcagagg ataccaagac agtccaaaat
     9601 ggttacttcg aggatgcagc tgtcaaggac cgcaccttga gtgactatgc aggtaactgg
     9661 caatcagttt atcctttcct tgaagacggc acgtttgacc aagtctttga ctacaaggct
     9721 aagttgactg gtaagatgac ccaggctgag tacaaggctt actatacaaa aggctatcag
     9781 acagatgtga ctaagattaa cattactgat aatactatgg aatttgttca aggtggacaa
     9841 agcaagaaat acacttacaa gtatgtcggt aagaaaattt tgacttacaa gaaaggcaat
     9901 cgtggcgtgc gtttcctctt tgaagccaca gatgctgacg ctggacaatt caagtatgtt
     9961 cagtttagtg atcacaatgt tgccccagtt aaggcagaac atttccatat cttctttgga
    10021 ggcacaagcc aagaagccct ctttgaagaa atggacaact ggccaaccta ctacccagat
    10081 aacctatctg gccaagaaat cgcccaagaa atgttggcgc attgatgaga aatcgactag
    10141 ttcataagag ctagtcggtt ttttgatact agatggctaa cttcattata gacctttcag
    10201 aactttaaac aataaataaa actcttgaaa tatctgggct tatatgctag aatgtagtta
    10261 gtgtataagg ttcattagaa caccaaagcc cctaactagt gccatagtta agggcttttt
    10321 tgacgtatct tagcgattta acgggtgttt ataggctagt cagtcggtct acttcttacc
    10381 atctagccat ttgcagacga aatacaagat aattccagct ataacatctg ctataatagt
    10441 aagagcaagc tctggtataa ggctcattag tttcacctcc tctcacgaac ccataggaac
    10501 gtaatcggta accgatgaca aaaatagtat accacactaa atttagatca tcaacctcac
    10561 ttaatgcttg aactattgta gattatatgc taaaatgtag ttaattgata aggttcatta
    10621 gaacaccaaa gcccctaact atggccgtag ttaagggctt ttttgacgta tcttagcgat
    10681 ttaacgggtg tttataggct agtcactcgg tctactcctt actatctagc catctgcaga
    10741 cgaaatacaa gataattcca gctataacat ccgctataat agtaagagcg agctctatga
    10801 taaggctcat tagtttcacc tcctctcacg aacccatagg aacgtaatcg gtaaccgatg
    10861 acaaaaatag tataccacaa tatatttaga tcatcaaggt cacttaattc ttgaaatata
    10921 gggtctaggc gacaaagtct ttaaaatcag aaaaacgcat aatatcaggt gtgcaaaaac
    10981 ttgatactat gcgttttatt gtgggaaggt ttactccatt ttctcctgaa attgagtttt
    11041 tgtccagcct ctgtttttag aattgctaag aaaataatgt catgtggtga atatttgtaa
    11101 atcagtcagc agacagaacg aatactcttc gaaaatctct tcacatcatg tcagcttcgt
    11161 cttgccgtgt ccatggggga cttgacttga tcagttttca aatctgtact ttgagcaagc
    11221 tgagactagc ttcctatttg attttcattg aatatcagaa acccattctc catcaaataa
    11281 ttcgactgcg tctaataatt tttggtctgg caaggtgtca gaaataaagg ttgtgtattt
    11341 ggagagggga ttaattttaa aaaatccagt cttgtaaaat ttagaactat caatcagtaa
    11401 gatggtttca tgggctttgt caataatatt cttttttgaa atagcttggc tgagagaagc
    11461 ttcataaaca tattggtcat caatacctct tgctgaacaa aatgctaaat cgatattaaa
    11521 atgatctaat aaagaatttt ccttatcata gttgaccacg gaacaggatt gatgtttgac
    11581 ctcgccagat gtgataaaga ttttggagct atctttaaca gtttcagata gggtttgtgc
    11641 agtatgtaaa ccatttgtaa aaataatcaa attatcaagt tcagaaagat agggacaaag
    11701 ttcgtagaca gtagtactag aatctagata gatacacata ccagaccgaa taaagtcttt
    11761 agcgagacta gcgattagtc ttttttgcct agtactttct ccttcccgta tttgatgaga
    11821 aagttcaatt gtgttcatag aggacagggt cacgtatccg tgctttcttt tgataagacc
    11881 ttgattttct aagaaaatta aatcacgacg taaggtactt gtgctggaga aagtgatttc
    11941 tgccagctct tttacggcaa ttcttttttt ctttttaata atttcaatca attcaagtac
    12001 acgttcatct tttatcataa gctcctccta atttatcatt tcaactatat tatagcacaa
    12061 attggaggaa tttgaattat ttttatgaat attgggttaa catttgaaca ttattcaagt
    12121 aagcgttcac atattgaaaa aataaaacgt ggggattata ataaagttaa tcaaggacga
    12181 agagagaaga aaaatggaag cggttttagc aatagattta ggtgcgactt ctggaagagc
    12241 aatcgttggt tacctttctg aaaataaact agtaatggaa gaaataaatc gcttttctaa
    12301 tctacctatt agagtaaaag ggcatttatc ttgggatatt gactttctac tagctaaaat
    12361 tcttgaaagt atccgcttgg ctaatactag ttacaagatt ttatctatcg gtattgacac
    12421 atggggagtt gattttggac tgattgataa tgaaggtaag ctgttatcac aacctgttca
    12481 ttatcgtgat gaaagaacaa agggagtgtt aaaggaaata tctgaaatga ctgaattaga
    12541 aaaactgtat tcagagacag gaaatcagat tatggagata aataccttgt ttcaactctt
    12601 taaggcacgt caagaatctc ctgactcttt ctataagacc aataagattc ttttaatgcc
    12661 agatttgttt aattatctct tgacaggtaa gtttgctaca gaaaaaagca ttgcttcaac
    12721 aactcaatta tttgatccta ggagtcaaaa ttggaatcag aatatcttaa aactatttga
    12781 attggattca tctttacttc ctgaaattgt ttcagaggga aatgttcttg gaaggataaa
    12841 aaaggagtat ggtttaggcg atattcctgt tgtgaatgtt tgtagtcatg atacagcaag
    12901 tgcgattgtc tcagtaccta agacagaagg tagtttattt atttcatcag gtacttggtc
    12961 tttggttgga gtggaactta cttcaccgat tcttactacc gaatccttca gttatggatt
    13021 tacaaatgaa gtcggtaaag atggagtgat tacatttctg aagaattgta cagggttgtg
    13081 gatcatagag gaactaagac gttcatttga acgaagaggg aaagcctatt cttttgatga
    13141 tattaggaca atggtggaga aagaaaaaga aaatcttcct ctgattgata ctgaatcaac
    13201 tgaatttgca acagaatctg atatgcacaa gactttgaca gaatatctag cttatcatca
    13261 tgaaactaga gagtggacag atggacaact atttaagatt gtttatgaaa gcctagctga
    13321 aacgtatagg aaagcgatag agttattaga agaactaact cataaggttt ataagaggat
    13381 atatgtgatt ggaggaggtg ctagagccag ttattttaac caaatgattg ctgatagaac
    13441 tggtaaagag gttcttacag gtttgactga ggctacagct gtggggaata ttgttgtgca
    13501 gctcatagct atgggacaat taaaagggat ggaagaggct caccatgtta ttgaggagtt
    13561 tctacaatta gagagttatt actcccaaaa gaattaaaaa gattgagagt ttgtaaattt
    13621 gcctccctcc cccttcttag cttttgtgca ggaagggggg ataattggtg aattgaaaaa
    13681 tatttagtgt tttgatatga ggaggacaag gatgtcagat gtaaaacaag aattaattaa
    13741 atatggtaag aagctagtag aaacagattt gacgaaagga acaggtggga atctcagcgt
    13801 tttcgatcgt gaaaaacaat tgatggcaat taccccgtcg ggtattgatt tctttgaaat
    13861 caaagaatcc gatattgtag tgatggatat taatggaaat gttgtagagg gagaacgctt
    13921 gccatctagc gaatggtata tgcatttgat tcaatatcaa actcgtgatg atatcgatgc
    13981 aattatccat gctcatacaa cttatgcaac agtattagct tgtctcagag aaccacttcc
    14041 agcgagtcat tatatgattg cagtggcagg gaaagatgtt cgggtagctg agtatgcaac
    14101 atatggcacg aaagaattgg ctgtgaatgc agctaaagca atggaaggtc gtagagcagt
    14161 tttactagcg aatcatggaa ttttagcagg tgcacaaaat ttattgaatg catttaatat
    14221 tgttgaagaa gttgaatatt gtgcaaaaat ttattgttta gctaagaatt ttggagagcc
    14281 agtagttctt cctgatgagg agatggaatt gatggcagaa aaatttaaaa catacggtca
    14341 gagaaaatag ggaggatatt aatgttaaaa catataccga aaaatatttc tccagattta
    14401 ttgaagactt taatggaaat gggacatgga gatgaaatag tattagctga cgcgaattat
    14461 ccttctgcct catgtgcaaa taagctaatt cgttgtgatg gcgtaaatat tccagaatta
    14521 ttagattcca ttctgtattt aatgccatta gatagttacg tcgatagttc aattcagttt
    14581 atgaacgttg tttcgggtga tgatattcct aagatatggg gtacctatag acagatgatt
    14641 gaaggtcatg gtacagatct taaaacgatt acttatctta gaagagaaga cttttatgaa
    14701 cgtagtaaga aagcttatgc tattgttgct acaggagaaa cttcacttta tgctaatatt
    14761 atccttaaga aaggagtagt tgttgaaaga gaaaatgttt aatagaggaa ttttagttgc
    14821 cagtcatggt gattttgcta gcggagctct catgaccgca gaaatgtttg ttggtgagac
    14881 aacaaatgat agagttagga cattaggttt gatgcctgga gagaatattg tagagtttga
    14941 gcattatttt aaaaatcaag tggatgaact gttagactca aatcaagagg ttatcgtttt
    15001 gactgacttg attggaggaa gtcctaataa tgtggctttg tcacggtttt taaatttgga
    15061 ttcagttgat attgtaacag ggtttaatat tcctctccta gtggaattaa tatcaaatta
    15121 tgattcaaaa atcaatttag aagaaattgt tcacaatgct caaaatagtt tgtttaatgt
    15181 taaacaacaa cttaacgtag aggaggaaga aaatttatgt ctatagagtt tgttcgtatt
    15241 gatgaccgtc tggtacatgg tcaagttgtc actacgtggc taaaaaagta tgatattgag
    15301 caagttatca ttgttaatga tcgcatctca gaagataaaa cacgacaatc tattttaaag
    15361 atttctgcac cagtaggttt aaaaattgtt ttctttagtg taaaacggtt tgtggaagtt
    15421 ttaaactctg tgccaataaa aaagagaaca atgctgatat atacaaatcc aaaagatgtg
    15481 tatgattcta ttgaaggaaa tttaaaattg gagtacctca atgtaggaca gatgagtaaa
    15541 acggaggaaa atgaaaaggt aacgggaggt gtagctctag gtgaagaaga caaatattat
    15601 tttaagaaaa tagttgataa gggaacgaga gttgaaattc aaatggttcc taatgataaa
    15661 gttacaatgt tggaaaaatt tttataaaaa taatttaagg aggtacagta tatgctattc
    15721 acacaagcat tactggtgac attagttggg attattgcca ctattgacta taatggaccg
    15781 ttatttatga ttcaccgtcc gttagttaca agtgcaatgg ttggcttagt cttaggagat
    15841 ttcacccaag gtgttcttat tggttcagct cttgaattaa cttggctcgg tgtaacaggt
    15901 attggaggtt acactccacc agatactatt tcaggtgcga ttattggtac tgcatttggt
    15961 attttatctg gtcaaggaga aactgctggt atcgctatag cagttccaat tgcagttgct
    16021 acccaacagt tggatgttct tgcaaaaact ttagatgttt attttgtgaa aaaagctgat
    16081 aatgatgcta aaaacggaga ttattcaaag atcggttttt atcattattc aagtttggtt
    16141 ttaatcacgt tatttaaaat tgtaccaatt ttcctagcta ttatgcttgg aggggaatat
    16201 gtggcagact tgtttgctaa ggttccacca atcgttatgc agggacttaa ctctgcaggt
    16261 gctttactac cttcaattgg ttttggtatg cttttaaata tgatgctcaa gaaaaatatg
    16321 tgggtattct tgttgattgg attcatttgt tctgtgtatg gaggaatgtc aaccattggg
    16381 atctcactag ttggtattgc ggtagcatac ttctacgata tgattggaag taaaccacaa
    16441 gaaacaactt caagtagtga tgttgaggag gatcttgatc tatgatgaat aataaagtaa
    16501 ctaaagttga acttaaaaaa gttttcaaac gaagttttat gtatggttct tcatggaact
    16561 atgagagaat gcagaaccta ggttttctat atacaattct tccagtattg aaaaaactat
    16621 acccagacaa agattcagct tctcctgcaa tgaaacgtca ccttgagttt ttcaatactc
    16681 atcaaacagc ggcaccattt attcttggag ttacttccgc tatggaagaa caagaaggaa
    16741 atgaaggtgc agcttcaatt actggtatta aagttggctt gatggggcca ctggctggtc
    16801 taggagatag tttgttctgg ctgacactag ttcctatctg ttttagtatt ggtgcgtctt
    16861 attctaaaga cggcggtgct ttaggtatct ttatcgcctt aatattgttt aatattatta
    16921 atattcctgt taaatatttc ggtttgaaat atgggtatac taagggttct agtcttatcc
    16981 aagaaaataa tacaaaagga acattgaatc gcgttacgag tatggcgaca gcattagggc
    17041 tagtactagt gggtggtttg attccatcaa tggttggtat taattttgga ttagaattta
    17101 agcaggggga acttgttatt tctgttcaag aaatgattac aaaattaatt ccaggattta
    17161 tccctatggc tttgacttta ttaatgtgta aattaattag aaaaggaaag aatccggttg
    17221 tactaatctt tagtgttatg gctattggag ttatcctagt tgttttagga attttgaagt
    17281 agtagaaagt gtggaggtgg tatttgggat atcacctcca ttttggaaga gaggtaaaga
    17341 gtgaaattat ggtataagaa agctgcctca aattggaatg aagccttgcc gattgggaac
    17401 ggtcatttag gtggtatgat ttatggttca gctacaaaag aatgtattca actaaacgat
    17461 gagactattt ggtatagagg aaagtcagat agaaataatc cagactcact attgcatctt
    17521 aaaaaaattc gggaatatct tttagatgga gaaattcaga aagccgaaga attgataaag
    17581 ttaacaatgt ttgctacccc aagagatcaa agccactatg aattacttgg ggaactttac
    17641 attgagcata tagatattca gtcttgtgct ctttcattgt atgaaagaga gctagattta
    17701 gatacagcta tttctaatgt tgtgtttgag cctaatagtt gtaatttaca aataaaaaga
    17761 gaatatttta cgagttttaa taagaatatt ttatgttgcc gtatagtgtc atcagttcaa
    17821 aacacattaa atttaaacat taatttgggt agaaataaac ggtttaatga cgaagtatct
    17881 aaactggatt caagtacaat tttaatgtcg gcctctgctg gaggtagaaa aggtgttcag
    17941 tttaaagtag tatgtcattc taaagttacg gatggtgaag taagtgtatt gggagagaca
    18001 atagttattc ggaatgctac agaggtattt ctttatctca aatcaatgac ggattattgg
    18061 ggaaatatag atatttcttc tcttcaggga gaatttagta gtattgatta ctttacagaa
    18121 aaagatgaac atgtaaaaaa atatcaggag caatttaata gagttgattt taaactagac
    18181 tatagtaaag attgtcttag cattccaacg aatctacttc ttgaaaacac taaaaagtat
    18241 agtaactact tgactaactt gttatttcat tatggaagat atctgttaat atcgtctagt
    18301 caaccgaatg gtttacctgt caatcttcaa ggaatatggt gtgatgaatt aaatccaatt
    18361 tggggttcta aatatacgat taatattaat actcaaatga attattggat ggtaggtcca
    18421 tgtgatttac cagaagtaga atatccatta tttgatatgc tcgaaagaat gagagaaccg
    18481 ggaagactaa ccgctaagaa aatgtatgga gctagaggtt ttacagcaca tcataatacg
    18541 gatggttttg gcgatacggc tccccaatct catgccatgg gggctgcaat ttgggtatta
    18601 actattccat ggttatgtac tcatatttgg gaacactatt tatatttcca agatgagcgt
    18661 attcttacgg aacattttga aatgataaaa gaagcatttc ttttctttga agattattta
    18721 tttgaggtgg atggctactt gatgacaggt ccaagtgtct caccggaaaa taaatatcgc
    18781 ttaaaaaatg gtattgaagg aaatgcttgt ctatcatcta caattgataa tcaaattcta
    18841 agatattttt gtgattcatg cattggcatt gcaaaacaat taggagacaa ttcggatttt
    18901 attagtcgtg tgaaggagtt aaaaaagaaa ctacctaaaa caaaaatagg tagtaatggg
    18961 caaatccaag aatggttaga agattatgaa gaagtagagc ctgggcatag acacatttca
    19021 cctctatttg ggctttatcc ttataatgag attgatattc ataaaactcc ggaattagca
    19081 gaagcagcta aaatcactat caataggaga ttatcaaacg ctaacttttt atcttcacag
    19141 gagagggagc aagcgattaa taattggtta gtaagtggtt tgcatgctag tacacaaaca
    19201 ggttggagtg ctgcatggct gattcatttt tttgcgagac tatatcaagg tgaacctgct
    19261 tataaccaga ttaatggttt gttaaataat gcgactcttg gcaatttatt tcttgaccat
    19321 ccaccatttc aaattgatgg taatttaggt ttggtgagtg gaatttgtga attattagta
    19381 cagagccatc ataattggtt atcactaatt ccagctttac cttctgcttg gtcagaagga
    19441 gaagtgaaag gtttcagagt aagaggagga tataaggtat cgtttgcttg gaaaaatggg
    19501 gatataacat tcctaaaatt ggaaggagga aacaaagatc aaaaagtaag agtaagaata
    19561 tatggcaaaa atactgatgt acaaaatatt gaattggtat ttaattcaga aaaaattatt
    19621 gagttaaatt tttaggtata agtcatgaat aaagaaaaaa taaaaagaaa attaatcaca
    19681 atactgtttg tatgtattgg gatgttatgt tttggattgt tagcaggagt taaggctgat
    19741 aatcgtgttc aaatgagaac gacgattaat aatgaatcgc cattgttgct ttctccgttg
    19801 tatggcaatg ataatggtaa cggattatgg tgggggaaca cattgaaggg agcatgggaa
    19861 gctattcctg aagatgtaaa accatatgca gcgattgaac ttcatcctgc aaaagtctgt
    19921 aaaccaacaa gttgtattcc acgagatacg aaagaattga gagaatggta tgtcaagatg
    19981 ttggaggaag ctcaaagtct aaacattcca gttttcttgg ttattatgtc ggctggagag
    20041 cgtaatacag ttcctccaga gtggttagat gaacaattcc aaaagtatag tgtgttaaaa
    20101 ggtgttttaa atattgagaa ttattggatt tacaataacc agttagctcc gcatagtgct
    20161 aaatatttgg aagtttgtgc caaatatgga gcgcatttta tctggcatga tcatgaaaaa
    20221 tggttctggg aaactattat gaatgatccg acattctttg aagcgagtca aaaatatcat
    20281 aaaaatttgg tgttggcaac taaaaatacg ccaataagag atgatgcggg tacagattct
    20341 atcgttagtg gattttggtt gagtggctta tgtgataact ggggctcatc aacagataca
    20401 tggaaatggt gggaaaaaca ttatacaaac acatttgaaa ctggaagagc tagggatatg
    20461 agatcctatg catcggaacc agaatcaatg attgctatgg aaatgatgaa tgtatatact
    20521 gggggaggca cagtttataa ttttgaatgt gccgcgtata catttatgac aaatgatgta
    20581 ccaactccag catttactaa aggtattatt cctttcttta gacatgctat acaaaatcca
    20641 gctccaagta aggaagaagt tgtaaataga acaaaagctg tattttggaa tggagaaggt
    20701 aggattagtt cattaaacgg attttatcaa ggactttatt cgaatgatga aacaatgcct
    20761 ttatataata atgggagata tcatattctt cctgtaatac atgagaaaat tgataaggaa
    20821 aagatttcat ctatattccc taatgcaaaa attttgacta aaaatagtga ggaattgtct
    20881 agtaaagtca actatttaaa ctcgctttat ccaaaacttt atgaaggaga tgggtatgct
    20941 cagcgtgtag gtaattcctg gtatatttat aatagtaatg ctaatatcaa taaaaatcag
    21001 caagtaatgt tgcctatgta tactaataat acaaagtcgt tatcgttaga tttgacgcca
    21061 catacttacg ctgttgttaa agaaaatcca aataatttac at
//
LOCUS       DAVBBO010000038        21070 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ST1
            SAMEA2066453-rid20184263.denovo.038, whole genome shotgun sequence.
ACCESSION   DAVBBO010000038 DAVBBO010000000
VERSION     DAVBBO010000038.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2066453
            Sequence Read Archive: ERR351777
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 21070)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 21070)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980402.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980402.1
            Genome Coverage       :: 176x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:17:33
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,141
            CDSs (total)                      :: 2,104
            Genes (coding)                    :: 1,953
            CDSs (with protein)               :: 1,953
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 16S)
            partial rRNAs                     :: 1 (23S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 151
            CDSs (without protein)            :: 151
            Pseudo Genes (ambiguous residues) :: 0 of 151
            Pseudo Genes (frameshifted)       :: 73 of 151
            Pseudo Genes (incomplete)         :: 76 of 151
            Pseudo Genes (internal stop)      :: 40 of 151
            Pseudo Genes (multiple problems)  :: 32 of 151
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..21070
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2066453-rid20184263.denovo.038"
                     /strain="ST1"
                     /db_xref="taxon:1313"
     gene            182..658
                     /locus_tag="VQU30_001395"
     CDS             182..658
                     /locus_tag="VQU30_001395"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000777685.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HET2447495.1"
                     /translation="MKLSLYSEVEHYHFLSSYSLNDITYTDTPKNIIEKSKKDKYRYP
                     IVILNKDHKVIGFFCLHLNTGPKEYGYYQNDYALIRGFSIHDNFRNQGYGSNALNEIF
                     EFIDSTLKLEINHIILAVNEKNILAQKAYRNSGFSVVKKDLEGKRGKLIIMEKSRN"
     gene            complement(1332..1724)
                     /locus_tag="VQU30_001396"
     CDS             complement(1332..1724)
                     /locus_tag="VQU30_001396"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398032.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence protein ComGF"
                     /protein_id="HET2447496.1"
                     /translation="MWKKKKVKAGVLLYAVTIAAIFSLLLQFYLTRQIAHYQDYALNK
                     EKLVAFAMAKRTKDKAEQESGEQVFNLGQVSYQNKKTSLVTTVRTDKSQYEFLFPSVK
                     IKEEKTDKKEEVATDSSEKAEKKIRREA"
     gene            complement(1702..2163)
                     /locus_tag="VQU30_001397"
     CDS             complement(1702..2163)
                     /locus_tag="VQU30_001397"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000250539.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence protein ComGF"
                     /protein_id="HET2447497.1"
                     /translation="MVQNSCWQSKSHKVKAFTLLESLLALIVISGGLLLFQAMSQLLI
                     SEVRYQQQSEQKEWLLFVGQLEAELDRSQFEKVEGNRLYMKQDDKDIAIGKSKSDDFR
                     KTDASGRGYQPMVYGLKSAQITEDNQLVHFRFQFQKGLEREFIYRVEKEES"
     gene            complement(2126..2386)
                     /locus_tag="VQU30_001398"
     CDS             complement(2126..2386)
                     /locus_tag="VQU30_001398"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000601743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2447498.1"
                     /translation="MILLEAVVALAIFASIATLLLGQIQKNRQEEAKILQKEEVLRVA
                     KMALQTGQNQVSINGVEIQVFSSEKGLEVYHGSEQLLAIKEP"
     gene            complement(2391..2819)
                     /locus_tag="VQU30_001399"
     CDS             complement(2391..2819)
                     /locus_tag="VQU30_001399"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012386909.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II secretion system protein"
                     /protein_id="HET2447499.1"
                     /translation="MEGQIVKSMIKAFTMLESLLVLGLVSILALGLSGSVQSTFAAVE
                     EQIFFMEFEELYRETQKRSVASQQKTSLNLDGQMISNGSQKLTVPKGIQAPSGQSITF
                     DRAGGNSSLAKVEFQTSKGAIRYQLYLGNGKIKRIKETKN"
     gene            complement(2788..3114)
                     /locus_tag="VQU30_001400"
     CDS             complement(2788..3114)
                     /locus_tag="VQU30_001400"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000738626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prepilin-type N-terminal cleavage/methylation
                     domain-containing protein"
                     /protein_id="HET2447500.1"
                     /translation="MKKMMTFLKKAKVKAFTLVEMLVVLLIISVLFLLFVPNLTKQKE
                     AVNDKGKAAVVKVVESQAELYSLDKNEDATLSKLQGDGRITEEQVKAYNEYYTKNGGA
                     NRKVND"
     gene            complement(3116..4132)
                     /locus_tag="VQU30_001401"
     CDS             complement(3116..4132)
                     /locus_tag="VQU30_001401"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000355375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II secretion system F family protein"
                     /protein_id="HET2447501.1"
                     /translation="MDISQVFRLRRKKLATAKQKNIITLFNNLFSSGFHLVETISFLD
                     RSSLLDKQCVTQMRTGLSQGKSFSEMMESLGCSSTIVTQLSLAEVHGNLHLSLGKIEE
                     YLDNLAKVKKKLIEVATYPLILLDFLLLIMLGLRNYLLPQLDSSNIATRIIGNLPQIF
                     LGMVGLVSVLALLALTFYKRSSKMSVFSILARLPFIGIFVQTYLTAYYAREWGNMISQ
                     GMELTQIFQMMQEQGSQLFKEIGQDLAQTLKNGREFSQTIGTYPFFRKELSLIIEYGE
                     VKSKLGSELEIYAEKTWEAFFTRVNRTMNLVQPLVFIFVALIIVLLYAAMLMPMYQNM
                     EVNF"
     gene            complement(4080..5021)
                     /locus_tag="VQU30_001402"
     CDS             complement(4080..5021)
                     /locus_tag="VQU30_001402"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000249584.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II/IV secretion system protein"
                     /protein_id="HET2447502.1"
                     /translation="MVQEIAQEIIRSARKKGTQDIYFVPKLDAYELHMRVGDERCKIG
                     SYDFEKFAAVISHFKFVAGMNVGEKRRSQLGSCDYAYDQKMASLRLSTVGDYRGHESL
                     VIRLLHDEEQDLHFWFQDIEELGKQYRQRGLYLFAGPVGSGKTTLMHELSKSLFKGQQ
                     VMSIEDPVEIKQDDMLQLQLNEAIGLTYENLIKLSLRHRPDLLIIGEIRDSETARAVV
                     RASLTGATVFSTIHAKSIRGVYERLLELGVSEEELAVVLQGVCYQRLIGGGGIVDFAN
                     RDYQEHQAAKWNEQIDQLLKDGHITSLQAETEKISYS"
     gene            complement(5097..5462)
                     /locus_tag="VQU30_001403"
     CDS             complement(5097..5462)
                     /locus_tag="VQU30_001403"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004262492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1033 family protein"
                     /protein_id="HET2447503.1"
                     /translation="MYRVIEMYGDFEPWWFLEGWEEDIVASRKFDQYYDALKYYKTCW
                     FRLEQESPLYKSRSDLMTIFWDPEDQRWCDECDEYLQQYHSLALLQDEQVIPDEKLRS
                     GYEKQTSQERNRSCRMKLK"
     gene            complement(5613..6671)
                     /locus_tag="VQU30_001404"
     CDS             complement(5613..6671)
                     /locus_tag="VQU30_001404"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000649458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc-dependent alcohol dehydrogenase family
                     protein"
                     /protein_id="HET2447504.1"
                     /translation="MKAYTYVKPGLASFVDVDKPVIRKPTDAIVRIVKTTICGTDLHI
                     IKGDVPTCQSGTILGHEGIGIVEEVGEGVSNFKKGDKVLISCVCACGKCYYCKKGIYA
                     HCEDEGGWIFGHLIDGMQAEYLRVPHADNTLYHTPEDLSDEALVMLSDILPTGYEIGV
                     LKGKVEPGCSVAIIGSGPVGLAALLTAQFYSPAKLIMVDLDDNRLETALSFGATHKVN
                     SSDPKKAIKEIYDLTDGRGVDVAIEAVGIPETFDFCQKIIGVDGTVANCGVHGKPVEF
                     DLDKLWIRNINVTTGLVSTNTTPQLLKALESHKIEPEKLVTHYFKLSEIEKAYEVFSK
                     AADHHAIKVIIENDISEA"
     gene            complement(6834..7985)
                     /gene="nagA"
                     /locus_tag="VQU30_001405"
     CDS             complement(6834..7985)
                     /gene="nagA"
                     /locus_tag="VQU30_001405"
                     /EC_number="3.5.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylglucosamine-6-phosphate deacetylase"
                     /protein_id="HET2447505.1"
                     /translation="MPNYIKADQFFYPHGVRRGGYLELVDGKFGKHVEQIPEGAEVID
                     YTGYSIAPGLVDTHIHGYAGVDVMDNNIEGTLHTMSEGLLSTGVTSFLPTTLTATYEQ
                     LLAVTENLGNHYKEATGAKIRGIYYEGPYFTETFKGAQNPTYMRDPGVEEFHSWQKAA
                     NGLLNKIALAPERDGVEDFVRTVTGEGVTVALGHSNATFDEAKKAVDAGASVWVHAYN
                     GMRGLTHRELGMVGAMYQLPHTYAELICDGHHVDPKACEILIKQKGTENIALITDCMT
                     AGGLEDGDYMLGEFPVVVANGTARLKSTGNLAGSILKLKDGLKNVVEWGIANPHEAVM
                     MASFNPAKSVHIDDVCGQIREGYDADFIVLDKDLELVATYLDGVKRYQA"
     gene            complement(8138..9955)
                     /locus_tag="VQU30_001406"
     CDS             complement(8138..9955)
                     /locus_tag="VQU30_001406"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001220923.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyltransferase"
                     /protein_id="HET2447506.1"
                     /translation="MRIKWFSLIRIIGLLLVLLYHFFQTIFPGGFFGVDVFFTFSGFL
                     ITALLIEEFSKNNEIDLIGFFRRRFYRIVPPVVLMVLVTMPFTFLVRQDYVAGIGGQI
                     AGVLGFMTNFYELLTGGSYESQFIPHLFVHNWSLAVEVHYYILWGLAVWFLSKQAKSN
                     GQLKGMIFLLSATAFLISFFSMFIGSFLVTSYSSVYFSSLTHVYPFFLGSMLATIVGV
                     RQTTSLVKQLDKIWDLRKTLVVFGGGFGFLVLLTFFVKFTYLFAYLIGFLLASLAALA
                     MILAARVLHEKTHHIQEPKIISFLADTSYAVYLFHWPFYIIFSQLTSNLLAVLLTLIC
                     SYGFASLSFYVLEPWIAGKNTPILQTLRPLPYIHAILAAGTGILTFIVCMVTLLAPQV
                     GAFETDLTVNGLKQAATNIGQTKVMAERADANSLGIADGTMLIGDSVALRANTALQTA
                     LPGAQINAQVSVTTKTANEIMLNNSQNKFLPKTVVIATGVNNPENYKDDWDSIVKNLP
                     KGHHMILVTPYEGDKTKETYAIVEKAAAYMRELAEKTPYITIADWNQVAKEHPEIWAG
                     TDQVHFGSESSTIEAGAKLYADTIATALQTAQDKPVKSK"
     gene            complement(10056..11198)
                     /gene="tgt"
                     /locus_tag="VQU30_001407"
     CDS             complement(10056..11198)
                     /gene="tgt"
                     /locus_tag="VQU30_001407"
                     /EC_number="2.4.2.29"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004298827.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA guanosine(34) transglycosylase Tgt"
                     /protein_id="HET2447507.1"
                     /translation="MSDSPIKYRLIKKEKHTGARLGEIITPHGTFPTPMFMPVGTQAT
                     VKTQSPEELKEMGSGIILSNTYHLWLRPGDELIARAGGLHKFMNWDQPILTDSGGFQV
                     YSLADSRNITEEGVTFKNHLNGSKMLLSPEKAISIQNNLGSDIMMSFDECPQFYQPYD
                     YVKKSIERTSRWAECGLKAHRRPHDQGLFGIVQGAGFEDLRRQSAHDLVSMDFSGYSI
                     GGLAVGETHEEMNAVLDFTTQLLPENKPRYLMGVGAPDSLIDGVIRGVDMFDCVLPTR
                     IARNGTCMTSQGRLVVKNAQFAEDFTPLDPECDCYTCNNYTRAYLRHLLKADETFGIR
                     LTSYHNLYFLLNLMKQVRQAIMDDNLLEFRKYFVEKYGYNKSGRNF"
     gene            11328..12185
                     /locus_tag="VQU30_001408"
     CDS             11328..12185
                     /locus_tag="VQU30_001408"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF975 family protein"
                     /protein_id="HET2447508.1"
                     /translation="MNYPKIDLKTIRQESKHFQADTPRLFLLYILPSMLVILSGFLNP
                     LSRIHGTVLEQPFFSILGQILQTYLFPLLVSFIGTILLTSSVYATLTLMKDSKTEPSV
                     KNSLALFDEERFSQTFLTLLLKRFYLFLWSIPNLLGIYLLFYSSFLAKKFVTLHPEFP
                     NLDLSSVETERFLMVFGLYFLASLILIIVGNILYIPQYYAYSQVEFLLCYSLDLGQVP
                     PRRILKTSRSFMKGYKFQHFVLDLQLLPWYFLNWITFGIASFSLLPYIQCTKIMFYRA
                     VLARKRPKA"
     gene            complement(12213..12857)
                     /gene="pcp"
                     /locus_tag="VQU30_001409"
     CDS             complement(12213..12857)
                     /gene="pcp"
                     /locus_tag="VQU30_001409"
                     /EC_number="3.4.19.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398107.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyroglutamyl-peptidase I"
                     /protein_id="HET2447509.1"
                     /translation="MKVLVTGFEPFGGEKGNPTLEAIKGLPAEIHGAEVRWLEVPTVF
                     HKSAQVLEEEMNRYQPDFVLCIGQAGGRTSVTPERVAINQDDARISDNEDNQPIDRPI
                     RPDGASAYFSSLPIKAMVQAIKKEGLPASVSNTAGTFVCSHLMYQALYLVEKKFPYVK
                     AGFMHIPYMMEQVVNRPTTPTMSLVDIRRGIEAAIGAMIEHGDQELKLVGGETH"
     gene            complement(12964..13332)
                     /locus_tag="VQU30_001410"
     CDS             complement(12964..13332)
                     /locus_tag="VQU30_001410"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000022857.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1304 domain-containing protein"
                     /protein_id="HET2447510.1"
                     /translation="MSIITIILTTIVALEHFYIFYLESIATRSDATSRVFNMEKEELA
                     HPSVSSLFKNQGIYKALLGVFLWYGIYFSQNLEIVTIFVLFVIGAATYGSLTADKKII
                     LKQGGSAILALISILLFKYT"
     gene            complement(13343..13768)
                     /locus_tag="VQU30_001411"
     CDS             complement(13343..13768)
                     /locus_tag="VQU30_001411"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000890080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="winged helix-turn-helix transcriptional
                     regulator"
                     /protein_id="HET2447511.1"
                     /translation="MIEIQDLLYQLRLSEQASTQLFEKRLGISLTRYQILLFLLEHSP
                     CNQMAVQERLKIDQAALTRHFKILETEGLVERHRNPENQREVLVEAAKYAKEQLVVNP
                     PLQHIKVKEEMESILTEFERTELSRLLNKLVLGIENIEI"
     gene            complement(14193..15335)
                     /locus_tag="VQU30_001412"
     CDS             complement(14193..15335)
                     /locus_tag="VQU30_001412"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000746996.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="HET2447512.1"
                     /translation="MKKRMLLASTVALSFAPVLATQAEEVLWTARSVEQIQNDLTKTD
                     NKTSYTVQYGDTLSTIAEALGVDVTVLANLNKITNMDLIFPETVLTTTVNEAEEVTEV
                     EIQTPQADSSEEVTTATADLTTNQVTVDDQTVQVADLSQPIAEAPKEVASSSEVTKTV
                     IASEEVAPSTGTSVPEEQTAETSSAVAEEAPQGTTPAEKQETQASPQAASAVEATTTS
                     SEAKEVASSNGATAAVSTYQPEETKIISTTYEAPAAPDYAGLAVAKSENAGLQPQTAA
                     FKEEIANLFGITSFSGYRPGDSGDHGKGLAIDFMVPERSELGDKIAEYAIQNMASRGI
                     SYIIWKQRFYAPFDSKYGPANTWNPMPDRGSVTENHYDHVHVSMNG"
     gene            complement(15501..16121)
                     /locus_tag="VQU30_001413"
     CDS             complement(15501..16121)
                     /locus_tag="VQU30_001413"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001172828.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HET2447513.1"
                     /translation="MQKTAFIWDLDGTLLDSYEAILSGIEETFAQFSIPYDKEKVREF
                     IFKYSVQNLLVRVAEDRNLDVEVLNQVRAQSLAEKNAQVVLMPGAREVLAWADESGIQ
                     QFIYTHKGNNTFTILKDLGVESYFTEILTSQSGFVRKPSPEAATYLLDKYQLNSDNTY
                     YIGDRTLDVEFAQNSGIQSINFLESTYEGNHRIQALADISRIFETK"
     gene            complement(16125..17405)
                     /locus_tag="VQU30_001414"
     CDS             complement(16125..17405)
                     /locus_tag="VQU30_001414"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000473957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MATE family efflux transporter"
                     /protein_id="HET2447514.1"
                     /translation="MFKKNKDILNIALPAMGENFLQMLMGMVDSYLVAHLGLIAISGV
                     SVAGNIITIYQAIFIALGAAISSVISKSIGQKDQSKLAYHVTEALKITLLLSFLLGFL
                     SIFAGKEMIGLLGTERDVAESGGLYLSLVGGSIVLLGLMTSLGALIRATHNPRLPLYV
                     SFLSNALNILFSSLAIFVLDMGIAGVAWGTILSRLVGLVILWSQLKLPYGKLTFGLDK
                     ELLTLALPAAGERLMMRAGDVVIIALVVSFGTEAVAGNAIGEVLTQFNYMPAFGVATA
                     TVMLLARAVGEDDWKRVASLSKQTFWLSLFLMLPLSFSIYVLGVPLTHLYTTDSLAVE
                     ASVLVTLFSLLGTPMTTGTVIYTAVWQGLGNARLPFYATSIGMWCIRIGTGYLMGIVL
                     GWGLPGIWAGSLLDNGFRWLFLRYRYQRYMSLKG"
     gene            complement(17466..18950)
                     /locus_tag="VQU30_001415"
     CDS             complement(17466..18950)
                     /locus_tag="VQU30_001415"
                     /EC_number="4.2.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006595200.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine synthase"
                     /protein_id="HET2447515.1"
                     /translation="MTLVYQSTRDANNTVTASQAILQGLATDGGLFTPVTYPKVDLDF
                     DKLKDASYQEVAKLVLSAFLDDFTAEELDYCINNAYDSKFDTPAIAPLVKLDGQYNLE
                     LFHGSTIAFKDMALSILPYFMTTAAKKHGLENKIVILTATSGDTGKAAMAGFADVPGT
                     EIIVFYPKGGVSKVQELQMTTQNGDNTHVIAIDGNFDDAQTNVKHMFNDVALREKLTT
                     NKLQFSSANSMNIGRLVPQIVYYVYAYAQLVKTGEIVAGEKVNFTVPTGNFGNILAAF
                     YAKQIGLPVGKLICASNDNNVLTDFFKTRVYDKKREFKVTTSPSMDILVSSNLERLIF
                     HLLGNNAEKTAELMNALNTQGQYKLTDFDAEILDLFAAEYATEEETAAEIKRVYESDS
                     YIEDPHTAVASAVYRKYQAVTGDVTKTVIASTASPYKFPVVAVEAVTGKAGLTDFEAL
                     AQLHEISGVAVPPAVDGLEIAPIRHKTTVAAADMQAAVEAYLGL"
     gene            complement(19026..20303)
                     /locus_tag="VQU30_001416"
     CDS             complement(19026..20303)
                     /locus_tag="VQU30_001416"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001277926.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gamma-glutamylcysteine synthetase"
                     /protein_id="HET2447516.1"
                     /translation="MSCSIDLLKHRYLKNIKENPELFVGIELEYPVASLEGDATDVEV
                     IKDLFHYLVSTLDLTVAKVDDFGNLIQLVDPISQDAILFEVSYTTIEFAFGKAETIQE
                     VENRFNNYMNVIQRKLAESNHAIVGCGIHPNWDKNENCPVAYPRYQMLMDYLNLSRNI
                     IKSDLHHFPEYGTFICGSQVQLDISKTNYLRVINAFTQIEAAKAYLFANSEFSGADWD
                     TKISRDIFWEESMHGIYPENVGVNARLLNDEADFFDYLNHSAIFTAERDGQTYYFYPI
                     QAGDYLATSEIQAFALNGDEVIIYPQEKDFETHRSYQYQDLTTRGTVEFRSVCTQPLD
                     RTFASAAFHLGLLVNLDKLEAYLETAPFFKVFGYDYKSLRRQFSKKNLTDEEETTIIE
                     FSKDLLLLAEEGLVVRNKEEMTYLQPLREELSL"
     gene            complement(20410..20493)
                     /locus_tag="VQU30_001417"
     tRNA            complement(20410..20493)
                     /locus_tag="VQU30_001417"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(20457..20459),aa:Leu,seq:caa)
     gene            complement(20503..20574)
                     /locus_tag="VQU30_001418"
     tRNA            complement(20503..20574)
                     /locus_tag="VQU30_001418"
                     /product="tRNA-Gln"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(20540..20542),aa:Gln,seq:ttg)
     gene            complement(20588..20660)
                     /locus_tag="VQU30_001419"
     tRNA            complement(20588..20660)
                     /locus_tag="VQU30_001419"
                     /product="tRNA-His"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(20625..20627),aa:His,seq:gtg)
     gene            complement(20675..20745)
                     /locus_tag="VQU30_001420"
     tRNA            complement(20675..20745)
                     /locus_tag="VQU30_001420"
                     /product="tRNA-Trp"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(20711..20713),aa:Trp,seq:cca)
     gene            complement(20750..20830)
                     /locus_tag="VQU30_001421"
     tRNA            complement(20750..20830)
                     /locus_tag="VQU30_001421"
                     /product="tRNA-Tyr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(20794..20796),aa:Tyr,seq:gta)
     gene            complement(20843..20915)
                     /locus_tag="VQU30_001422"
     tRNA            complement(20843..20915)
                     /locus_tag="VQU30_001422"
                     /product="tRNA-Phe"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(20880..20882),aa:Phe,seq:gaa)
     gene            complement(20919..20992)
                     /locus_tag="VQU30_001423"
     tRNA            complement(20919..20992)
                     /locus_tag="VQU30_001423"
                     /product="tRNA-Met"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(20956..20958),aa:Met,seq:cat)
BASE COUNT         6295 a         4801 c         3726 g         6248 t
ORIGIN      
        1 tggtattatc aatcatgaac taggattcta gttttgcagg aagtctaata atgaaaataa
       61 aggactaaag caataactct aaatacatct gatttttata ggatatttca taaaaaaaat
      121 ctacatacct agagtcctat ttagttatgt atcttacata aagagaaagg aattaattat
      181 catgaaatta tctttgtata gtgaagttga acattaccat tttttaagtt cttattcttt
      241 aaatgatatt acatatactg ataccccaaa aaatattatt gaaaagtcta aaaaagataa
      301 gtatagatac ccaatagtaa tacttaataa agaccataaa gtaattggat ttttttgcct
      361 acacctaaac actggtccta aagagtatgg ctattatcaa aatgattatg cgcttattag
      421 aggattttct attcatgata atttcagaaa tcaaggatat ggttctaatg ctctgaatga
      481 aatatttgaa ttcatagact caactttaaa attagaaatt aaccatatta tattggctgt
      541 aaatgaaaaa aatatattgg ctcaaaaagc atatagaaat tccggttttt ctgttgtgaa
      601 aaaagattta gaaggaaaaa gggggaaatt aattattatg gagaaaagca gaaactagta
      661 atgatactag tttctgcttt tctctaagtc tgctataaat ttataacatg ttgaaataag
      721 atgtgaataa attgattgca gaattcaaac caatttctaa caatgtttta gaaaactcgg
      781 cggactattc cagattcaat ccactatatt ctatcttatt tgcatatttt gagagaaata
      841 atctatatac taaactttta tgtttataat tcattccttt cgtttcactc aaggcacaag
      901 acagaatgaa aaagtggtgt gctctttatt ttgttttata ataatagtga gaaaacctat
      961 cactactaca aatcacgggg aggtgaataa gtgagtggta tagccactac ctcgcatttt
     1021 tataggtgtc attctttcca tcaagcacaa gaactgtgac taggagcacg taaacttata
     1081 attgaataag cgactcgttt gtgaaaggaa agaatagtca agggataggc agactcaaat
     1141 ttggtgaagg gaaacccctc atgttaaaag ccaaacttca attttaaaaa ttttaaaatt
     1201 tgtttcgtat tcactactcc ttgcctttat attggattga ttaagagaac ctttcgcgtt
     1261 tctagaaact acagtggact attctggatt caacgcatta tagttgaatt gactaggaat
     1321 tctctttctt ttcaggcttc tcttctgatt tttttctccg ctttttcgct tgaatcagtc
     1381 gctacctctt cctttttatc cgttttctct tctttgattt tgactgaagg aaacagaaac
     1441 tcatattgac tcttatccgt acgaacagtc gtcaccaagc ttgttttctt gttttgatag
     1501 ctcacctgac ctagattaaa aacctgttcc ccactttctt gctcggcttt atccttggtt
     1561 cgtttagcca tggcaaaagc aaccaatttt tctttattta aagcatagtc ttgatagtgg
     1621 gcgatttgtc gggtcaaata aaattgcaac aaaagactaa agatggctgc tatggtgact
     1681 gcgtagagga gaacacctgc cttaactttc ttctttttcc acacgataga tgaactccct
     1741 ttctaagcct ttttgaaact ggaaacgaaa atgaaccagt tgattgtcct ctgtaatctg
     1801 agctgatttg aggccataaa ccataggctg atacccccgt ccactagcat cggttttacg
     1861 aaaatcgtct gactttgact taccgatggc gatgtccttg tcatcttgct tcatgtatag
     1921 gcgattgcct tctacttttt cgaactgcga acggtctaat tctgcctcaa gttggcccac
     1981 aaacaagagc cactcctttt gctcgctttg ttgctggtag cgaacttctg aaatgaggag
     2041 ctgactcata gcttgaaaaa ggagtaatcc cccactgatg acaatgaggg caagcaggga
     2101 ttctaacaag gtaaaagcct tgaccttatg gctctttgat tgccaacaac tgttctgaac
     2161 catggtagac ctccaatccc ttttcactag aaaatacctg aatctcaact ccgttgatgc
     2221 ttacctgatt ttgccccgtc tgcaaggcca tcttagctac cctcaagact tcttcctttt
     2281 gcaagatttt tgcttcctct tgcctatttt tttgaatttg tcccaaaagg agggtcgcaa
     2341 tgctggcaaa gatagctaga gcgactactg cttccagtaa aatcactgcc ctaatttttt
     2401 gtttccttaa tgcgtttaat ttttccattt cctagatata attgatagcg aatcgctcct
     2461 ttactggtct gaaattcaac cttagccagg gacgaattgc ccccagctcg gtcaaatgta
     2521 atactttggc ctgatggtgc ctgaattcct ttaggaactg tcaacttttg actgccattg
     2581 ctaatcatct gcccatccaa gttcagacta gtcttttgtt gactagctac actgcgtttt
     2641 tgggtttccc gatagagttc ttcaaactcc ataaagaaaa tctgttcctc taccgctgca
     2701 aaagtggact ggacagagcc ggacaagccc aaggcaagga tactcacaag tcccaaaacc
     2761 aagagacttt ccagcatggt aaaggcctta atcattgact ttacgatttg cccctccatt
     2821 tttagtatag tattcattat aagctttaac ctgttcttcc gtgatgcgcc catctccttg
     2881 taacttgctc agagtagcat cttcattttt atccaagcta taaagttctg cctggctttc
     2941 caccacctta acaacagctg cttttccttt gtcattgact gcttcttttt gcttggtcag
     3001 attaggtaca aagagcaaga aaagcacgct gataatcagc aagaccacca acatctccac
     3061 caatgtaaaa gctttaacct tagctttttt caagaatgtc atcatttttt tcattttaaa
     3121 aatttacctc catattttga tacatgggca tgagcattgc cgcataaagt aaaacgataa
     3181 tcagtgccac aaagataaaa accagtggct gcaccaaatt catggtgcgg ttgactcggg
     3241 taaaaaaggc ttcccaagtt ttttcagcat agatttccaa ctcactaccc agcttggact
     3301 taacttcccc atactctatg atgagactca attccttcct aaagaaagga taggttccta
     3361 tcgtctgaga aaattcacgg ccatttttca gggtttgagc cagatcttga ccgatttctt
     3421 taaagagctg ggaaccttgt tcctgcatca tttgaaaaat ctgcgtcagc tccattccct
     3481 gtgaaatcat attcccccat tcacgtgcat aataggctgt caagtaggtc tgcacaaaga
     3541 ttccaataaa gggaaggcgt gctaagatag aaaagacact catcttagaa cttcttttat
     3601 aaaaagttag tgctaaaagg gcaagcacgg aaacaagccc taccatgcct agaaaaattt
     3661 gtggcagatt accgataatt cgggtggcaa tattgctact atccagttgt gggagcaggt
     3721 aattccgtag ccccagcata attaagagaa gaaaatccag caaaatcaaa ggataggtcg
     3781 ctacttcaat taactttttc ttgaccttgg ccagattgtc tagatattct tctatctttc
     3841 ccaaactcag gtgaagattg ccatgaactt cagctagaga taactgagtg acaatggtac
     3901 ttgaacatcc caaactttcc atcatttctg agaatgattt cccctgagac aagcctgtac
     3961 gcatctgggt cacacactgc ttgtccaaca aggaactcct atctaaaaag gagatagtct
     4021 ccaccagatg aaaaccgcta gaaaagagat tgttaaatag ggtgatgata tttttttgct
     4081 tagctgtagc taattttttc cgtctcagcc tgaagacttg tgatatgtcc atctttaaga
     4141 agttggtcaa tttgctcatt ccacttggct gcttggtgtt cttgataatc tctgtttgca
     4201 aagtcaacga ttcctcctcc cccgattaat ctctggtagc agactccttg cagaacaact
     4261 gccaattctt cttcactcac acccaactcc agcagacgct cataaacacc tcggatactc
     4321 ttggcgtgaa tggttgaaaa gactgtcgca cctgtcaaac tagctctgac cactgcacgc
     4381 gccgtctcgc tgtcacgaat ttctccgata atcaagagat ctggtcgatg acgcaaggaa
     4441 agtttgatta gattttcata ggttaggccg attgcttcgt tcaactgcaa ctgaagcatg
     4501 tcgtcctgct tgatttcgac aggatcttcg atggacataa cttgctgtcc tttaaagagt
     4561 gacttggaca attcatgcat caaggtcgtc ttaccactcc caaccgggcc agcaaaaaga
     4621 tagagtcccc gttgcctgta ctgcttgcct aattcttcaa tatcctgaaa ccaaaaatgc
     4681 aagtcctgct cctcatcgtg caacaaacgg ataaccaaac tctcatgccc ccgataatcg
     4741 cctacagtag ataaacgtag agacgccatc ttctggtcat aggcataatc acaggaaccc
     4801 agttgactac gtcttttttc tcccacattc atacccgcca caaacttaaa gtgactgata
     4861 acggctgcaa acttttcaaa atcatagcta ccaattttac agcgctcgtc tcctaccctc
     4921 atatgaagct cataggcgtc taacttaggg acaaaataaa tatcctgcgt cccttttttc
     4981 cgagctgaac gaatgatttc ttgtgcaatt tcttgaacca tacttacctc ctcacctata
     5041 ctattcgcaa agcgttagaa aaataaaaaa agcaactcca aaaaagttac ttttctctat
     5101 tttaatttca tacggcaaga acgattcctt tcctgactgg tttgtttttc atagcctgag
     5161 cgtagttttt cgtctgggat aacctgctca tcctgcaaaa gagccaaaga atggtattgt
     5221 tgtaaatact catcacattc atcacaccag cgttggtctt ccgggtccca aaaaatggtc
     5281 atcaagtcgc ttctactttt ataaagaggg gattcttgtt ccaatctaaa ccagcaagtt
     5341 ttgtagtatt tgagagcatc ataatactgg tcaaattttc tacttgctac aatatcttct
     5401 tcccaacctt ctaagaacca ccacggttca aaatctccgt acatttctat aacacgatac
     5461 atattcattc attcctttgt accgtatatt ataaccaatt ccgccagaca aggaaagaaa
     5521 tatgctcatt tcttaatttt ttgataaaaa atccagccat ctgatggatg actgaatttc
     5581 tatttgctta tgtacaaaaa tatttttact acttaggctt ctgagatatc gttttcgata
     5641 atgaccttaa tggcatggtg gtctgctgcc ttactgaaga cttcgtaggc tttttcaatt
     5701 tcactgagtt tgaaatagtg agttaccaat ttttccggtt caatcttatg actttcaagt
     5761 gctttcaaca attgtggagt cgtatttgta gataccaaac cagttgttac attgatgttg
     5821 cgaatccaaa gtttatctaa atcgaattca actggtttac catgcacacc acagttggca
     5881 accgttccgt ctacaccgat aatcttttga cagaaatcaa atgtttcagg aatccctaca
     5941 gcttcgatag cgacatccac accacgacca tctgtcaaat cataaatttc tttaatggct
     6001 tttttagggt ctgaagaatt aaccttatga gtcgcaccga atgatagggc agtttccaag
     6061 cggttatcgt ctaggtctac cataatcaat ttagctggtg aatagaattg ggctgttaaa
     6121 agagcagcca atccaactgg acctgaacca ataatggcta cgctgcaacc aggttctact
     6181 ttccctttta agacaccaat ttcatatcca gtaggcagaa tgtctgacag cataaccaaa
     6241 gcttcatctg acaagtcttc tggagtatgg taaagagtat tatctgcatg agggacacgt
     6301 agatattcag cctgcatacc atcaatcaag tgaccgaaaa tccagccccc ttcgtcttca
     6361 cagtgggcat aaattccttt tttacagtag tagcatttac cacaggcaca gacgcaagaa
     6421 atcaagacct tgtcaccttt tttgaagttg gaaactcctt ccccaacttc ttcaacaatc
     6481 ccaatccctt cgtggccaag aatggtacca ctttggcaag taggaacatc ccctttgata
     6541 atatggaggt ctgttccaca aatagtggtt tttacaatac gcacaatagc gtctgttggc
     6601 ttgcgaataa ctggtttgtc tacatcaaca aaagaagcaa gtcctggttt aacataagta
     6661 taggctttca taaagcactc ctccgttttt ttatttgtaa tatttatagt tcaattgtaa
     6721 gcctttttct ttgtttcttc aagctttttt tgtgattttt ttaacttttt atttaccagt
     6781 aaagtaccct gtataaaaaa gcagaagcta gtctctaact tctgccttct ctcttatgct
     6841 tgataacgtt tcacaccatc taggtaggtt gctaccaatt ccaaatcttt atctaatacg
     6901 atgaagtcag cgtcgtagcc ttcacggatt tggccacaga cgtcatcgat gtgaacggat
     6961 ttagctgggt tgaagctggc catcatgact gcttcatgcg gattcgcaat tccccattcg
     7021 accacattct tcaaaccatc tttgagtttg aggatagaac ctgccaagtt acctgtcgat
     7081 ttgaggcgtg cagttccatt tgcaacgaca actgggaatt ctcccaacat ataatctccg
     7141 tcttccaatc ccccagctgt catacagtct gtgataagag cgatgttttc tgttcctttt
     7201 tgtttgataa gaatttcgca agcctttgga tctacgtggt gaccatcaca gatcaactct
     7261 gcataggtat gtggcaattg gtacatggct ccaaccatac ccaattcacg gtgagtcaac
     7321 ccacgcattc cattgtaggc atgcacccaa acactcgctc cagcatcgac tgcttttttg
     7381 gcttcatcaa aagtcgcgtt tgaatgtcca agagcaaccg tcacaccttc gcccgtaact
     7441 gtacgaacaa agtcttccac cccatcacgt tctggtgcaa gggcaatttt attaagcaag
     7501 ccatttgccg ctttttgcca agaatgaaac tcctcaacac ccgggtctct catataagtt
     7561 ggattttgtg cccccttaaa agtttctgtg aaatatggac cttcataata aatcccacga
     7621 atcttagcac ctgttgcttc tttataatgg tttccaagat tttcagtgac tgcaagcaat
     7681 tgctcataag tggctgttaa agttgtgggt aagaaactgg taacaccggt actaagaagt
     7741 ccttcactca tagtatgcaa tgtaccttca atgttgttgt ccatcacatc tacacctgca
     7801 tatccatgaa tatgagtatc cacaagtcct ggggcaatgc tataacctgt atagtcaatc
     7861 acctcagccc cttcaggaat ctgctctaca tgtttcccaa acttgccgtc cacaagttcc
     7921 aagtaaccac ctcgacgaac tccgtgtggg tagaaaaact gatccgcttt aatatagtta
     7981 ggcataatgt taacctcctt aaaagattga ttctacaatt tattatgtca attacattat
     8041 aaacctttct tttttatttg taaatggtat agacctattt tttggagata ttttaaaaga
     8101 gctggatttc tccaactctt ctctttttta atacaagtta ttttgattta accggcttgt
     8161 cttgagctgt ctgcaaagct gtggcaatcg tatctgcata caattttgct cctgcttcga
     8221 tagtgctact ctcactcccg aaatgaacct ggtctgttcc agcccaaatt tctggatgct
     8281 ctttcgcaac ttgattccaa tctgctatcg taatgtaagg tgtcttctct gccaattctc
     8341 tcatataggc agcagccttc tcaacgatgg cataggtctc ttttgtctta tctccctcat
     8401 aaggagtcac caaaatcata tggtgtccct taggaagatt tttcacgata ctgtcccagt
     8461 catccttgta attctcagga ttatttaccc cagtcgcaat gaccaccgtc ttaggtaaaa
     8521 atttattctg gctattattt agcatgattt catttgcggt cttggttgtt acgctgacct
     8581 gcgcgttaat ctgtgctcca ggaagagctg tctgtagtgc tgtatttgcc cttaaagcca
     8641 ctgagtcacc aattaacata gtgccatcag caattcccaa actgtttgca tctgcccgtt
     8701 ctgccatcac cttggtctgg ccaatatttg ttgcagcttg cttcaagcca ttgacagtca
     8761 agtctgtctc aaacgctccc acttgtggtg ccaacaaggt caccatgcag acaatgaagg
     8821 tcaagattcc tgtacctgct gcaagaattg cgtgaatata aggcagggga cgaagagttt
     8881 gtaaaatagg tgtgttcttg cctgcaatcc aaggttccaa tacataaaat gacagactgg
     8941 caaagccata agaacaaatc agagtcagta atacagcaag aagatttgat gtcaactgtg
     9001 agaaaatgat atagaaaggc caatggaaaa gataaaccgc atagctagta tccgctaaaa
     9061 agctgataat cttcggctcc tgtatatgat gtgtcttttc atgtaagaca cgcgccgcca
     9121 gaatcatggc aagagctgca agactggcaa gcaagaagcc gataagatag gcaaaaagat
     9181 aagtgaattt gacaaagaaa gtcaaaagaa ctaggaaacc aaagcctcct ccaaaaacta
     9241 ctaaagtctt tcgtaaatcc cagattttat ccaactgctt gacgagggaa gtcgtctgac
     9301 gaacgcctac aatagttgct aacatacttc ccaaaaagaa tggatagaca tgagttaaac
     9361 tggagaaata aacagaggaa taagaggtca ctagaaaact accaataaac atggagaaga
     9421 aactgatcaa gaaggcagta gcagataaga gaaagatcat ccccttcaac tgaccatttg
     9481 atttagcttg tttggataag aaccaaactg ccaatcccca aagaatatag tagtgaacct
     9541 caactgccaa actccaatta tgaacaaaca aatgaggaat gaactgagat tcataactcc
     9601 cacctgttaa gagttcatag aagttggtca taaagcctaa gacgcccgca atctggccac
     9661 caattccagc aacatagtct tggcgaacca agaaagtaaa aggcatggtc accaagacca
     9721 tcaaaaccac aggtggcaca atccgataaa agcgtcttct aaaaaatcct atcaaatcaa
     9781 tctcattgtt cttagaaaat tcttcaatga gtagagctgt aatcaggaaa cctgaaaatg
     9841 tgaaaaagac atctaccccg aaaaatcctc caggaaagat cgtctgaaag aagtgataca
     9901 agagtaccaa aagtaaacct ataatcctaa tcaaggaaaa ccatttaatg cgcatacgag
     9961 tttattcttc ctttcattgt acactttatt ctatcaaaaa aagaagaaaa atcctaagag
    10021 aaaacttagg atttttagct tatatcaatt ccattttaga aattacgtcc tgacttatta
    10081 tagccatatt tttccacaaa atacttacgg aattccaaga gattgtcatc catgatggct
    10141 tgtcgcactt gcttcatcag gttaagcaag aagtaaagat tgtggtagct agtcaagcgg
    10201 ataccaaagg tttcatcagc cttgagcagg tgacgaaggt aagcgcgtgt atagttatta
    10261 catgtgtagc aatcacactc aggatccagt ggcgtaaagt cctcagcaaa ctgggcattt
    10321 ttcacaacca aacgtccttg actggtcata caagtcccgt tacgagcaat tcgagtcggt
    10381 aagacacagt caaacatatc caccccacga atgaccccat cgatcaagct atctggcgct
    10441 cccacaccca tcagataacg aggtttattt tcaggcagca gttgagttgt aaagtccaag
    10501 accgcattca tctcttcatg ggtttctccc actgccaaac caccgataga gtagcctgag
    10561 aaatccatgc tgacaagatc gtgagctgat tggcggcgaa ggtcttcaaa tcctgcacct
    10621 tgcacaattc caaacaaacc ttggtcatgt ggacgacggt gagccttcaa accacactca
    10681 gcccaacggc tggtacgctc gatcgatttc ttaacgtagt cataaggttg ataaaactga
    10741 ggacattcat caaaggacat catgatgtct gaacccagat tattctgaat agagatggct
    10801 ttttctgggg ataggagcat cttagaacca tttagatgat ttttaaaggt tactccttct
    10861 tctgtgatat tacggctatc tgctaaagaa taaacctgaa aaccaccact atctgtcaag
    10921 ataggctggt cccaattcat gaacttgtgg agaccaccag cgcgtgcaat gagttcatct
    10981 ccagggcgaa gccagagatg ataggtgttt gataggataa ttcccgaacc catctccttc
    11041 aattcttcag gtgactgagt tttgacagtg gcttgtgtcc caactggcat aaacataggt
    11101 gtcggaaagg taccgtgggg agtgatgatt tctcctagac gagctcctgt gtgtttttct
    11161 ttcttaatca aacgatattt gattggtgaa tctgacattt tttacctccg aagctgggaa
    11221 agacagtccc agttcataca gtgtgcccaa ggacacactg tatgatttta tcaaaaaaag
    11281 taggaactgt cacgaactat gtataagaac tatggtataa taagagaatg aactatccaa
    11341 aaattgattt aaaaacaatt cgtcaggagt caaaacattt tcaggctgac accccccgtc
    11401 tctttctcct ctatatcctt cccagtatgc tggtcatctt atctggtttt cttaatccct
    11461 tatctcggat ccacgggact gttttagaac agccattttt cagcatactt ggccaaatac
    11521 ttcaaaccta cctctttcct ctactagtct cctttatcgg gactattctt ttgaccagtt
    11581 ccgtctatgc aacactgaca ctcatgaaag attctaaaac ggagccatct gtaaaaaaca
    11641 gcctagctct ctttgatgag gagcgctttt ctcaaacctt tttgacccta cttctcaaac
    11701 gtttctatct ctttttatgg agtatcccta atttacttgg gatttacctc ctcttttata
    11761 gtagcttttt agccaaaaaa ttcgtcaccc tacatcctga gtttccaaat ctagatctct
    11821 catcagttga aaccgagcgt ttcctcatgg tctttggact ctactttctt gcaagtctca
    11881 tcttgatcat tgtaggaaat atcctctata ttccacagta ttatgcctat tcacaggtgg
    11941 aatttcttct ctgttatagt ctagacctag gacaggtccc accaagacga atcctaaaaa
    12001 ctagccgttc ctttatgaag ggctacaagt tccagcactt tgtcctagat ttacagcttc
    12061 ttccttggta cttcctcaat tggattacct ttggcattgc tagtttttca ctcctacctt
    12121 atatccaatg cactaaaatt atgttttacc gagcagtatt ggctcgaaaa cgtccaaaag
    12181 cttgaaggtt tttcccctca agcttttttc tatcaatgag tttctccgcc taccaacttg
    12241 agttcctgat ctccatgttc tatcatagcg ccgattgctg cttctatccc tcgccgaata
    12301 tccactaaac tcatagttgg agtagtcggt ctgttcacca cctgttccat catataagga
    12361 atatgcataa aacctgcctt aacatatgga aatttctttt ctaccaaata gagagcctga
    12421 tacatcaaat ggctgcagac aaaagtccct gccgtattgg aaacagaggc cggtaagccc
    12481 tcttttttta tagcttgaac catcgcttta atcggcaaac tactaaagta ggccgaagca
    12541 ccatctgggc gaatgggacg gtcaatcggt tgattatctt cgttatcaga aatgcgtgca
    12601 tcgtcttgat taatggccac tcgttcaggt gtcacactag ttcttccacc agcttgccca
    12661 atacaaagga caaagtcagg ttgataacga ttcatctctt cttccaatac ttgagcagat
    12721 ttgtgaaaaa ctgtcggcac ctctagccaa cggacctcag caccatggat ttcagctggt
    12781 aaacctttaa tggcctccaa agttggattg cccttttccc ctccaaaggg ctcaaaacct
    12841 gtcactaata ctttcatttc taactcctca aaaccaattc aatgagactt ttttcttaaa
    12901 aacaagtata acatatttcc cttattctgg attaaaaagg attagcgaga ttaaaatcga
    12961 ccttcaagtg tatttaaaga gtaaaatact aatcaaggcc aaaatagctg atccaccttg
    13021 cttcaaaata atttttttat ccgctgttaa agagccgtaa gtcgcagcac caatcacaaa
    13081 taagacaaaa atagtcacaa tttctaaatt ctgtgagaaa taaatgccat accagagaaa
    13141 gactcctagc agagccttat aaatcccttg atttttgaac aatgaactta ctgacggatg
    13201 agccaattct tccttttcca tattaaatac acgactagtc gcatctgatc gcgtagcaat
    13261 actttccaaa taaaaaatgt aaaaatgctc caaagcaacg atcgttgtta aaataattgt
    13321 aataattgac atctatttct ccttaaattt ctatattttc aatacccaaa accaatttat
    13381 ttaataaacg gctgagttct gttctctcaa actctgttaa gatactttcc atctcttcct
    13441 taaccttgat atgttgcaga gggggattca ccactaactg ctccttggca tacttcgcag
    13501 cctctaccaa cacttcccgc tgattttcag gattacgatg acgctccacc aaaccttccg
    13561 tttccaaaat cttgaaatgc cgtgtcaaag cagcctgatc aattttcaaa cgctcctgaa
    13621 ccgccatttg gttacaagga gaatgctcca gcaaaaacag taaaatctga taccgtgtca
    13681 aactaatccc aagccttttt tcaaacaatt gcgtactcgc ttgctcagac aagcggagtt
    13741 gatacagtaa atcttgaatc tctatcattt cttcctccta tccattgact tatcaatagt
    13801 tgaccaatca attataatat aaagtatagt gaaatgaaat aagagcagga caaatcgatc
    13861 aggacagtca aatcgatttc taacaatgtt ttagaagcag ttgtgtacta ttctagtttc
    13921 aatctactat aaaatagatt gcaagaatgt tgcttagatt attacaagat gataactttc
    13981 cattttccat tcaaattgat actcaatgaa aatcaaaaag caaactagga agctagtcgc
    14041 aggttgctca aagcacagct ttgaggtttc agataaaact gacgtggttt gaagagattt
    14101 tcgaagagta tgacaaagaa aaaacgaacg agaatcgctt cccatcacga aagctagatc
    14161 tcattcgtca aaatgatgtt accaagtcgg gtttatccat tcattgaaac gtgaacgtga
    14221 tcatagtgat tttctgtcac actaccacgg tctggcattg ggttccaagt gttagctggc
    14281 ccatatttgc tatcgaatgg agcatagaaa cgttgtttcc agatgatgta actaatgcca
    14341 cggctggcca tgttttgaat agcatattcc gcaatcttat cccctaattc tgaacgttct
    14401 ggtaccataa agtcgatagc caaacctttt ccgtgatctc cactgtctcc tggacgataa
    14461 ccgctaaagg atgtaatgcc aaacaagtta gcaatttctt ctttaaaggc agctgtttgt
    14521 ggttgaagac ctgcattttc agattttgct actgcaagtc cagcataatc gggcgcagct
    14581 ggagcctcgt aagttgttga aattattttc gtctcttctg gttgataagt agaaactgct
    14641 gctgtagctc catttgatga tgctacttct tttgcttctg aacttgttgt agttgcttcc
    14701 actgctgatg cagcttgagg gcttgcttgt gtttcctgct tctcagctgg agtcgttccc
    14761 tgaggagctt cttctgcaac tgcactgctt gtttcggccg tttgctcctc tgggacagaa
    14821 gtgcccgtag atggtgccac ttcttcagaa gcaatcactg tctttgtaac ttctgaactt
    14881 gatgctactt cttttggagc ttctgcaatt ggttgagaaa ggtctgcaac ctgaacagtt
    14941 tgatcatcaa cggtcacttg attagtggtc aaatctgctg tcgcagttgt cacttcttca
    15001 ctagagtctg cttgaggtgt ttggatttca acttctgtta cttcttctgc ttcattgaca
    15061 gtcgttgtca aaacagtttc tgggaaaatc aagtccatat tagtgatttt gttcagattc
    15121 gcaagcactg tgacatctac acccaaggct tctgcaatgg tgctcaaagt atcaccatac
    15181 tgtacggtat aacttgtttt gttgtccgtt ttagtcaaat cgttttggat ttgctcaaca
    15241 ctacgtgcag tccaaagaac ttcttctgct tgagttgcca atactggggc aaatgacaag
    15301 gctactgttg acgctaataa cattcttttc ttcattcttt caaattcctt tcaaatgagt
    15361 acctgtctat cataacacaa aaaatgtaga aaaaaagccc tctcgggcct atttaacaga
    15421 actgtctatt ccttgtaaca aactagatta cttgaaatag tttgttaggt ctctgtcaca
    15481 aaactgacac aatcttttta tcacttagtc tcaaaaatac gggaaatatc tgctaacgct
    15541 tgaatcctgt gattcccttc ataagtagac tctaaaaagt tgatactttg aatcccacta
    15601 ttctgggcaa attccacatc cagagtccga tcccctatat aataagtatt atcagaattc
    15661 aactgatact tatctagcag ataggtagcc gcttctggac ttggcttccg cacaaagcca
    15721 ctctgactgg tcaaaatctc tgtaaaatag gattccaccc ccaagtcctt gagaatggta
    15781 aaagtgttgt tccccttatg agtatatata aactgctgaa ttcctgattc gtctgcccaa
    15841 gctagcacct cacgcgcacc tggcatcaaa actacctgag cattcttctc agccagactc
    15901 tgggcacgca cctgatttag cacctcaaca tccagatttc tatcttctgc cacccgcaca
    15961 agcaaatttt gcaccgaata cttgaagata aactctctca ccttctcctt atcataagga
    16021 atagaaaact gagcaaaagt ctcctcaatc cctgataaaa tcgcttcgta agagtccaat
    16081 aaagtcccgt ctaaatccca aataaaagct gttttttgca tttcctatcc tttcaagctc
    16141 atatagcgct ggtaacgata gcgtagaaat aaccagcgaa aaccattatc caagagagac
    16201 cctgcccaaa taccaggcaa gccccaacca agcacaatac ccatcagata tcctgtccca
    16261 atgcggatac accacatgcc tatacttgtc gcataaaaag ggaggcgtgc atttcctaat
    16321 ccctgccaga ctgccgtata gatgactgtt cctgtcgtca taggggtacc aagtagtgaa
    16381 aacagtgtca ctagaacact agcctccacc gctagagaat cagtcgtata gagatgagtt
    16441 aatggtacac ccaagacata tatactaaag gacaggggca acatgaggaa cagagaaagc
    16501 caaaaggttt gtttactcaa actagcaact cttttccaat catcctctcc aactgctcgg
    16561 gccaacagca tgaccgttgc cgtagcgaca ccaaaggcag gcatatagtt aaactgggtc
    16621 aagacttctc cgattgcatt cccagcaact gcctccgtcc caaaagaaac gaccaaggca
    16681 atgatcacta catctccagc cctcatcata agtcgctctc cagctgctgg taaagccaag
    16741 gtcaacagtt ccttatctaa accaaaagtt agcttcccat aaggcagttt taattgtgac
    16801 cacaaaatca caagaccaac caaacgagac agaattgtcc cccaagcaac accagctatc
    16861 cccatatcca gaacaaaaat agctagactt gaaaaaagaa tattcaaggc attggataaa
    16921 aaactaacat agagaggcag acgtggatta tgcgttgcac gaatcaaggc tcccaaacta
    16981 gtcattaaac ctaagagaac aatcgatccg cctaccaaag atagatacag tccaccactc
    17041 tcagctacat ccctctccgt ccccaaaagt cctatcatct ctttcccagc gaagatggac
    17101 aaaaatccta aaaggaaact taatagtaag gtaatcttca acgcctcagt cacatgatag
    17161 gccaacttcg actggtcttt ctgccctatg ctttttgaaa taacactgga aatagcagct
    17221 cccagagcga tgaaaatcgc ctgataaatg gtgataatat taccagctac tgaaacccct
    17281 gaaatagcta tcaatcctaa atgagcaacc aaataactgt ccaccattcc cattagcatc
    17341 tgcaaaaagt tttcacccat agctggcaat gcaatattaa gaatgtcttt atttttctta
    17401 aacaatctct cctcctgatg aaaagaaact cagttggttt cccaaccgag tttgctccct
    17461 ctgtcttaaa gtcctaaata agcctcaacc gctgcttgca tgtcagcagc tgccactgtt
    17521 gtcttgtgac gaattggagc tatttcaagc ccatcaactg ctggtggcac tgcaacgcct
    17581 gagatttcat gtaattgagc caaggcttca aagtctgtca aacctgcttt tccagttaca
    17641 gcttctactg caactactgg gaacttgtat ggactagctg ttgaagcaat cactgtctta
    17701 gttacatctc cagtaaccgc ttggtatttt ctataaactg ctgaggcaac cgccgtatgt
    17761 ggatcctcaa tataagaatc tgactcataa acacgcttga tttctgccgc tgtttcttcc
    17821 tcagtcgcat attcagctgc aaagaggtcc aaaatctctg catcaaagtc tgtcaactta
    17881 tattgtcctt gcgtgttcaa ggcattcata agttcagctg tcttttcagc attatttccc
    17941 aaaagatgga aaatcaagcg ctccaagttt gaagatacca agatatccat agatgggctg
    18001 gttgttacct taaactcacg ttttttgtca tagacacgtg ttttaaagaa gtctgtcaag
    18061 acattattgt catttgaagc acagattagc ttgccaactg gtaggccgat ttgtttggca
    18121 taaaaggcag ccaagatatt tccaaagttt cctgttggta ctgtgaagtt aaccttttca
    18181 ccagctacaa tttcaccagt cttaaccaat tgagcgtaag cataaacata ataaacaatt
    18241 tgtggcacca gacgaccaat gttcatagag ttagctgatg aaaattgcaa cttgttggta
    18301 gtcaattttt cacgaagagc cacgtcgtta aacatgtgct tcacatttgt ttgcgcatcg
    18361 tcaaaattac catcaatagc aataacatga gtattgtcac cattctgagt ggtcatttgc
    18421 aactcttgta ccttgctgac accacccttt ggataaaaga cgataatctc agtaccaggc
    18481 acatccgcaa accccgccat agcagctttc cccgtgtcac cagatgtcgc tgtcaagata
    18541 acaatcttgt tctccaaacc atgtttctta gcagcagtcg tcataaagta tggcaaaata
    18601 gacaaggcca tatccttaaa ggcaatcgtt gaaccatgga aaagttccaa attgtattgc
    18661 ccatctaatt tcactaatgg tgcaatagct ggagtatcaa atttgctatc gtaggcattg
    18721 ttgatacagt agtccaactc ctcagctgta aagtcatcta aaaatgctga caaaactagc
    18781 ttagcaactt cctggtaaga agcatctttc aatttgtcaa agtccaaatc tacctttgga
    18841 taagtaaccg gtgtaaacaa accgccgtcc gtcgccaaac cttgcaaaat tgcttggctg
    18901 gcagttactg tattgttggc atcacgcgtt gattgataaa ctaatgtcat tactctctat
    18961 cctttatcta tagtctcgtc cattatatca tgatttttca gaaaattctc cctttataag
    19021 agaaattata ggctcaattc ttctctcaaa ggctgtaaat aggtcatttc ttccttattt
    19081 ctcaccacta gtccctcctc agctagtagg agtaagtctt tggaaaattc aataatcgta
    19141 gtttcttcct catctgtaag atttttctta gaaaattgtc tccttaaaga cttgtaatca
    19201 taaccaaata ctttaaagaa aggtgctgtt tctaagtaag cttctaactt gtctaaatta
    19261 accaataatc ccaagtgaaa agctgcagaa gcaaaagtcc tatcaagtgg ctgtgtacac
    19321 acactacgaa actcaactgt tcctcgagtc gttaaatctt ggtactggta actacgatga
    19381 gtttcaaaat ccttctcttg ggggtaaata ataacctcat ccccattcag agcaaatgct
    19441 tggatttcgg acgtagccaa atagtcccca gcctgaatag gataaaaata ataggtctgc
    19501 ccatcacgtt ccgcagtaaa aatcgcagaa tgatttagat agtcaaaaaa atcagcttca
    19561 tcattaagga gtctagcatt gaccccaaca ttctctggat agataccatg catagattct
    19621 tcccagaaaa tatcccttga aattttcgta tcccaatccg cacccgaaaa ttcagagttt
    19681 gcaaataaat aagccttagc cgcttcaatt tgagtaaaag cattaatcac ccgtaagtag
    19741 ttggtttttg aaatatccag ctgaacctgg ctcccacaga taaaagtacc atattcaggg
    19801 aaatgatgta aatctgattt aataatattt ctactcaaat tcaaataatc catcaacatc
    19861 tgatagcgtg gataagccac tggacaattc tcatttttat cccagttggg atggatacca
    19921 cagccaacaa tagcatgatt tgattcagct aactttctct gaattacatt catataatta
    19981 ttgaaacgat tttcgacctc ttgaatcgtt tcagccttac caaatgcaaa ctcaatcgtt
    20041 gtataggaaa cttcaaataa aatagcatcc tgacttatcg gatctactaa ctggatcaga
    20101 ttgccaaaat catctacctt tgctacggtg agatccaaag tagaaactaa ataatgaaat
    20161 agatccttta taacttcaac atctgtagca tccccttcta aacttgcaac aggatactcc
    20221 aactcaattc cgacaaacaa ttcaggattt tctttaatat ttttcaaata ccgatgtttt
    20281 aataaatcga tagaacaaga catactaccc tacactttct taatctaaat aaaatttgaa
    20341 taactataat tataccaaaa ataatataaa aaaggaacga agaataacaa cgttcctaac
    20401 actatactat accggcggcc ggggtcgaac cggcacgtcc ttgcggacac tggattttga
    20461 gtccagcgcg tctgccaatt ccgccacgcc ggcaaatagt aactggggta gctggattcg
    20521 aaccaacgca tgagggagtc aaagtccctt gccttaccgc ttggctatac cccaataata
    20581 taaaataggc gagtgatggg gatcgaaccc acgcatgcca gagccacaat ctggtgtgtt
    20641 aaccacttca ccacacccgc cataattcta ttaacacggg cagtaggaat tgaacccaca
    20701 ctgaaggttt tggagacctt agttctacct ttaaactatg cccgtaaaat ggaaggggag
    20761 ggattcgaac ccccgaaccc gaaggagcgg atttacagtc cgccgcgttt agcctcttcg
    20821 ctacccttcc aaaatatata aatggcgcga gacggaatcg aaccgccgac acatggagct
    20881 tcaatccatt gctctaccaa ctgagctacc gagccttatt gcgggagcag gatttgaacc
    20941 tacgaccttc gggttatgag cccgacgagc taccgagctg ctccatcccg cgttaataat
    21001 ataaaaggag gatgtgggat tcgaacccac gcacgctttt acacgcctga cggttttcaa
    21061 gaccgttccc
//
LOCUS       DAVBBO010000039        20733 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ST1
            SAMEA2066453-rid20184263.denovo.039, whole genome shotgun sequence.
ACCESSION   DAVBBO010000039 DAVBBO010000000
VERSION     DAVBBO010000039.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2066453
            Sequence Read Archive: ERR351777
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 20733)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 20733)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980402.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980402.1
            Genome Coverage       :: 176x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:17:33
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,141
            CDSs (total)                      :: 2,104
            Genes (coding)                    :: 1,953
            CDSs (with protein)               :: 1,953
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 16S)
            partial rRNAs                     :: 1 (23S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 151
            CDSs (without protein)            :: 151
            Pseudo Genes (ambiguous residues) :: 0 of 151
            Pseudo Genes (frameshifted)       :: 73 of 151
            Pseudo Genes (incomplete)         :: 76 of 151
            Pseudo Genes (internal stop)      :: 40 of 151
            Pseudo Genes (multiple problems)  :: 32 of 151
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..20733
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2066453-rid20184263.denovo.039"
                     /strain="ST1"
                     /db_xref="taxon:1313"
     gene            complement(4..924)
                     /gene="cysK"
                     /locus_tag="VQU30_001424"
     CDS             complement(4..924)
                     /gene="cysK"
                     /locus_tag="VQU30_001424"
                     /EC_number="2.5.1.47"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000029859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine synthase A"
                     /protein_id="HET2447517.1"
                     /translation="MSIYNNITELIGQTPIVKLNNIVPEGAADVYIKLEAFNPGSSVK
                     DRIALSMIEKAEQDGILKLGSTIVEATSGNTGIGLSWVGAAKGYKVVIVMPETMSVER
                     RKIIQAYGAELVLTPGSEGMKGAIAKAQEIAAERDGFLPLQFDNPANPEVHERTTGAE
                     ILAAFGKDGLDAFVAGVGTGGTISGVSHALKSENSNIQVFAVEADESAILSGEKPGPH
                     KIQGISAGFIPDTLDTKAYDGIVRVTSDDALALGREIGGKEGFLVGISSAAAIYGAIE
                     VAKKLGTGKKVLALAPDNGERYLSTALYEL"
     gene            complement(1209..1844)
                     /locus_tag="VQU30_001425"
     CDS             complement(1209..1844)
                     /locus_tag="VQU30_001425"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000395753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YigZ family protein"
                     /protein_id="HET2447518.1"
                     /translation="MEFRTIKEDGQVQEEIKKSRFICHAKRVYSEEEARDFITAIKKE
                     HYKATHNCSAFIIGERSEIKRTSDDGEPSGTAGVPMLGVLENHNLTNVCVVVTRYFGG
                     IKLGAGGLIRAYAGSVALAVKEIGIIEIKEQAGIAIQMSYAQYQEYSNFLKEHDLMEL
                     DTNFTDQVDTMIYVDKEEKETIKAALVEFFNGKVTLTDQGLREVEVSVNLV"
     gene            1900..3198
                     /locus_tag="VQU30_001426"
     CDS             1900..3198
                     /locus_tag="VQU30_001426"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000867598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HET2447519.1"
                     /translation="MKVNLDYLGRLFTENELTEEERQLAEKLPAMRKEKGKLFCQRCN
                     STILEEWYLPIGAYYCRECLLMKRVRSDQTLYYFPQEDFPKQDVLKWRGQLTPFQEKV
                     SEGLLQAVDKQKPTLVHAVTGAGKTEMIYQVVAKVINAGGAVCLASPRIDVCLELYKR
                     LQQDFSCGIALLHGESEPYFRTPLVVATTHQLLKFYQAFDLLIVDEVDAFPYVDNPTL
                     YHAVKNSVKENGLRIFLTATSTNELDKKVRLGELKRLSLPRRFHGNPLIIPKPIWLSD
                     FNRYLDKNRLSPKLKSYIEKQRKTAYPLLIFASEIKKGEQLEEILQEQFPNEKIGFVS
                     SVTEDRLEQVQAFRDGELTILISTTILERGVTFPCVDVFVIEANHRLFTKSSLIQIGG
                     RVGRSMDRPTGDLLFFHDGLNASIKKAIKEIQMMNKEAGL"
     gene            3195..3857
                     /locus_tag="VQU30_001427"
     CDS             3195..3857
                     /locus_tag="VQU30_001427"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000649954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ComF family protein"
                     /protein_id="HET2447520.1"
                     /translation="MKCLLCGQTMKTVLTFSSLLLLRNDDSCLCSDCDSTFERIGEEN
                     CPNCMKTELSTKCQACQFWCKEGVEVSHRAIFTYNQAMKDFFSRYKFDGDFLLRKVFA
                     SFLSEELKKYKEYQFVVIPLSPDRYANRGFNQVEGLVEAAGFEYLDLLEKREERASSS
                     KNRSERLGTELPFFIKSGVTIPKKILLIDDIYTTGATINRVKKLLEEAGAKDVKTFSL
                     VR"
     gene            3937..4485
                     /gene="raiA"
                     /locus_tag="VQU30_001428"
     CDS             3937..4485
                     /gene="raiA"
                     /locus_tag="VQU30_001428"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000599099.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome-associated translation inhibitor RaiA"
                     /protein_id="HET2447521.1"
                     /translation="MIKYSIRGENLEVTEAIRDYVVSKLEKIEKYFQPEQELDARINL
                     KVYREKTAKVEVTIPLGSITLRAEDVSQDMYGSIDLVTDKIERQIRKNKTKIERKNKN
                     KVATGQLFTDALVEDSNIVQSKVVRSKQIDLKPMDLEEAILQMDLLGHDFFIYVDVED
                     QTTNVIYRREDGEIGLLEVKES"
     gene            4621..6594
                     /locus_tag="VQU30_001429"
     CDS             4621..6594
                     /locus_tag="VQU30_001429"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255323.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DHH family phosphoesterase"
                     /protein_id="HET2447522.1"
                     /translation="MKKFYVSPIFPILVGLIAFGVLSTFIIFVNNNLLTVLILFLFVG
                     GYVFLFKKLRVHYTRSDVEQIQYVNHQAEESLTALLEQMPVGVMKLNLSSGEVEWFNP
                     YAELILTKEDGDFDLEAVQTIIKASVGNPSTYAKLGEKRYAVHMDASSGVLYFVDVSR
                     EQAITDELVTSRPVIGIVSVDNYDDLEDATSESDISQINSFVANFISEFSEKYMMFSR
                     RVSMDRFYLFTDYTVLEGLMNDKFSVIDAFREESKQRQLPLTLSMGFSYGDGNHDEIG
                     KVALLNLNLAEVRGGDQVVVKENDETKNPVYFGGGSAASIKRTRTRTRAMMTAISDKI
                     RSVDQVFVVGHKNLDMDALGSAVGMQLFASNVIENSYALYDEEQMSPDIERAVSFIEK
                     EGVTKLLSVKDALGMVTNRSLLILVDHSKTALTLSKEFYDLFTQTIVIDHHRRDQDFP
                     DNTVITYIESGASSASELVTELIQFQNSKKNRLSRMQASVLMAGMMLDTKNFTSRVTS
                     RTFDVASYLRTRGSDSIAIQEIAATDFEEYREVNELILQGRKLGSDVLIAEAKDTKCY
                     DTVVISKAADAMLAMSGIEASFVLAKNTQGFISISARSRSKLNVQRIMEELGGGGHFN
                     LAAAQIKDVTLSEAGEKLTEIVLNEIKEKEKEE"
     gene            6591..7043
                     /gene="rplI"
                     /locus_tag="VQU30_001430"
     CDS             6591..7043
                     /gene="rplI"
                     /locus_tag="VQU30_001430"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011999581.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L9"
                     /protein_id="HET2447523.1"
                     /translation="MKVIFLADVKGKGKKGEIKEVPTGYAQNFLIKKNLAKEATAQAV
                     GELRGKQKSEEKAHAEMIAEGKAIKAQLEAEETVVEFVEKVGPDGRTFGSITNKKIAE
                     ELQKQFGIKIDKRHIQVQAPIRAVGLIDVPVKIYQDITSVINLRVKEG"
     gene            7087..8439
                     /gene="dnaB"
                     /locus_tag="VQU30_001431"
     CDS             7087..8439
                     /gene="dnaB"
                     /locus_tag="VQU30_001431"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000852490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replicative DNA helicase"
                     /protein_id="HET2447524.1"
                     /translation="MAEVEELRVQPQDILAEQSVLGAIFIDESKLVFVREYIESRDFF
                     KYAHRLIFQAMVDLSDRGDAIDATTVRTILDNQGDLQNIGGLSYLVEIVNSVPTSANA
                     EYYAKIVAEKAMLRRLIAKLTESVNQAYEASQPADEIIAQAEKGLIDVSENANRSGFK
                     NIRDVLNLNFGNLEARSQQTTDITGIATGYRDLDHMTTGLHEEELIILAARPAVGKTA
                     FALNIAQNIGTKLDKTVAIFSLEMGAESLVDRMLAAEGLVESHSIRTGQLTDEEWQKY
                     TIAQGNLANASIYIDDTPGIRITEIRSRSRKLAQETGNLGLILIDYLQLITGTGRENR
                     QQEVSEISRQLKILAKELKVPVIALSQLSRGVEQRQDKRPVLSDIRESGSIEQDADIV
                     AFLYRDDYYERGGEEEEGIPNNKVEVIIEKNRSGARGTVELIFQKEYNKFSSISKREA
                     "
     gene            8441..8707
                     /locus_tag="VQU30_001432"
     CDS             8441..8707
                     /locus_tag="VQU30_001432"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001278167.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2447525.1"
                     /translation="MSDAFTDVAKMKKIKEEIKAHEGQVVEMTLENGRKRQKNRLGKL
                     IEVYPSLFIVEFGDVEGDKQVNVYVESFTYSDILTEKNLIHYLD"
     gene            8796..10142
                     /gene="cbpD"
                     /locus_tag="VQU30_001433"
     CDS             8796..10142
                     /gene="cbpD"
                     /locus_tag="VQU30_001433"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000698569.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choline binding-anchored murein hydrolase CbpD"
                     /protein_id="HET2447526.1"
                     /translation="MKILPFIARGTSYYLKMSVKKLVPFLVVGLMLAAGDSVYAYSRG
                     NGSIARGDDYPAYYKNGSQEIDQWRMYSRQCTSFVAFRLSNVNGFEIPAAYGNANEWG
                     HRARREGYRVDNTPTIGSITWSTAGTYGHVAWVSNVMGDQIEIEEYNYGYTESYNKRV
                     IKANTMTGFIHFKDLDGGSVGNSQSSTSTGGTHYFKTKSAIKTEPLVSATVIDYYYPG
                     EKVHYDQILEKDGYKWLSYTAYNGSYRYVQLEAVNKNPLGNSVLSSTGGTHYFKTKSA
                     IKTEPLVSGTVIDYYYPGEKVHYDQILEKDGYKWLSYTAYNGSRRYIQLEGVTSSQNY
                     QNQSGNISSYGSNNSSTVGWKKINGSWYHFKSNGSKSTGWLKDGSSWYYLKLSGEMQT
                     GWLKENGSWYYLGSSGAMKTGWYQVSGKWYYSYSSGALAVNTTVDGYRVNSDGERV"
     regulatory      10225..10327
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00059"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="TPP riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="thiamine pyrophosphate"
                     /db_xref="RFAM:RF00059"
     gene            10398..10688
                     /locus_tag="VQU30_001434"
     CDS             10398..10688
                     /locus_tag="VQU30_001434"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000647657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine-binding protein"
                     /protein_id="HET2447527.1"
                     /translation="MKASIALQVLPLAQGIDRIAVIDQVIAYLQTQEVTMVVTPFETV
                     LEGEFDELMRILKEALEVAGQEADNVFANVKINVGEILSIDEKLEKYTETTH"
     gene            10651..11409
                     /locus_tag="VQU30_001435"
     CDS             10651..11409
                     /locus_tag="VQU30_001435"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009013602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HET2447528.1"
                     /translation="MRNLKSILRRHISLLGFLGVLSIWQLAGFLKLLPKFILPTPLEI
                     LQPFVRDREFLWHHSWATLRVALLGLILGVLIACLMAVLMDSLTWLNDLIYPMMVVIQ
                     TIPTIAIAPILVLWLGYGILPKIVLIILTTTFPIIVSILDGFRHCDKDMLTLFSLMRA
                     NPWQILWHFKIPVSLPYFYAGLRVSVSYAFITTVVSEWLGGFEGLGVYMIQSKKLFQY
                     DTMFAIIILVSIISLLGMKLVDISEKYVIKWKRT"
     gene            11447..12454
                     /locus_tag="VQU30_001436"
     CDS             11447..12454
                     /locus_tag="VQU30_001436"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HET2447529.1"
                     /translation="MKKTWKVFLTLVTALVAVVLVACGQGTASKDNKEAELKKVDFIL
                     DWTPNTNHTGLYVAKEKGYFKEAGVDVDLKLPPEESSSDLVINGKAPFAVYFQDYMAK
                     KLEKGAGITAVAAIVEHNTSGIISRKSDNVSSPKDLVGKKYGTWNDPTELAMLKTLVE
                     SQGGDFEKVEKVPNNDSNSITPIANGVFDTAWIYYGWDGILAKSQGVDANFMYLKDYV
                     KEFDYYSPVIIANNDYLKDNKEEARKVIQAIKKGYQYAMEHPEEAADILIKNAPELKE
                     KRDFVIESQKYLSKEYASDKEKWGQFDAARWNAFYKWDKENGILKEDLTDKGFTNEFV
                     K"
     gene            12454..13182
                     /locus_tag="VQU30_001437"
     CDS             12454..13182
                     /locus_tag="VQU30_001437"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET2447530.1"
                     /translation="MTEIRLEHVSYAYGQERILEDINLQVTSGEVVSILGPSGVGKTT
                     LFNLIAGILEVQSGRIVLDGEENPKGRVSYMLQKDLLLEHKTVLGNIILPLLIQKVDK
                     AEAISRADKILATFQLTAVRDKYPHELSGGMRQRVALLRTYLFGHKLFLLDEAFSALD
                     EMTKMELHAWYLEIHKQLQLTTLIITHSIEEALNLSDRIYILKNRPGQIVSEIKLDWS
                     EDEDKEVQKIAYKRQILAELGLDK"
     gene            13301..13759
                     /locus_tag="VQU30_001438"
     CDS             13301..13759
                     /locus_tag="VQU30_001438"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001211265.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CtsR family transcriptional regulator"
                     /protein_id="HET2447531.1"
                     /translation="MRFKNTSDHIEAYIKAILDQSGIVELQRSQLADTFQVVPSQINY
                     VIKTRFTESRGYLVESKRGGGGYIRIGRIEFSSHHEMLRELLYSIGERVSQEIYEDIL
                     QLLVEQELMTKQEMNLLESVALDRVLGEEAPVVRANMLRQVIQEVDRKGK"
     gene            13761..16193
                     /locus_tag="VQU30_001439"
     CDS             13761..16193
                     /locus_tag="VQU30_001439"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001109706.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit"
                     /protein_id="HET2447532.1"
                     /translation="MNYSKALNECIESAYMVAGHFGARYLESWHLLIAMSNHSYSVAG
                     ATLNDYPYEMDRLEEVALELTETDYSQDETFMELPFSRRLQVLFDEAEYVASVVHAKV
                     LGTEHVLYAILHDGNALATRILERAGFSYEDKKDQVKIAALRRNLEERAGWTREDLKA
                     LRQRHRTVADKQNSMANMMGMPQTPSGGLEDYTHDLTEQARSGKLEPVIGRDKEISRM
                     IQILSRKTKNNPVLVGDAGVGKTALVLGLAQRIASGDVPAEMAKMRVLELDLMNVVAG
                     TRFRGDFEERMNNIIKDIEEDGQVILFIDELHTIMGSGSGIDSTLDAANILKPALARG
                     ALRTVGATTQEEYQKHIEKDAALSRRFAKVTIEEPSVADSMTILQGLKATYEKHHRVQ
                     ITDEAVETAVKMAHRYLTSRHLPDSAIDLLDEAAATVQNKVKYVKADDSDLSPADKAL
                     MDGKWKQAAQLIAKEEEVPVYKDLVTESDILTTLSRLSGIPVQKLTQTDAKKYLNLEA
                     ELHKRVIGQDQAVSSISRAIRRNQSGIRSHKRPIGSFMFLGPTGVGKTELAKALAEVL
                     FDDESALIRFDMSEYMEKFAASRLNGAPPGYVGYEEGGELTEKVRNKPYSVLLFDEVE
                     KAHPDIFNVLLQVLDDGVLTDSKGRKVDFSNTIIIMTSNLGATALRDDKTVGFGAKDI
                     RFDQENMEKRMFEELKKAYRPEFINRIDEKVVFHSLSSDHMQEVVKIMVKPLVASLAE
                     KGIDLKLQASALKLLANQGYDPEMGARPLRRTLQTEVEDKLAELLLKGDLVAGSTLKI
                     GVKAGQLKFDIA"
     gene            16835..17488
                     /gene="rr06"
                     /locus_tag="VQU30_001440"
     CDS             16835..17488
                     /gene="rr06"
                     /locus_tag="VQU30_001440"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001024075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system response regulator RR06"
                     /protein_id="HET2447533.1"
                     /translation="MNILVADDEEMIREGIAAFLTEEGYHVIMAKDGQEVLEKFQDLP
                     IHLMVLDLMMPRKSGFEVLKEINQKHDIPVIVLSALGDETTQSQVFDLYADDHVTKPF
                     SLVLLVKRIKALIRRYYVIEDIWRYQDVTVDFTSYKAHYKNEEIDLKPKELLVLKCLI
                     QHKNQVLSREQILEEISKDVADLPCDRVVDVYIRTLRKKLALDCIVTVKNVGYKISL"
     gene            17485..18825
                     /gene="hk06"
                     /locus_tag="VQU30_001441"
     CDS             17485..18825
                     /gene="hk06"
                     /locus_tag="VQU30_001441"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000594665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system sensor histidine kinase
                     HK06"
                     /protein_id="HET2447534.1"
                     /translation="MIKNPKLLTKSFLRSFAILGGVGLVIHIAIYLTFPFYYIQLEGE
                     KFNESARVFTEYLKTKTSDEIPSLLQSYSKSLTISAHLKRDIVDKRLPLVHDLDIKDG
                     KLSNYIVMLDMSVSTADGKQVTVQFVHGVDVYKEAKNILFLYLPYTFLVTIAFSFVFS
                     YFYTKRLLNPLFYISEVTSKMQDLDDNIRFDESRKDEVGEVGEVGKQINGMYEHLLKV
                     IHELESRNEQIVKLQNQKVSFVRGASHELKTPLASLRIILENMQHNIGDYKDHPKYIA
                     KSINKIDQMSHLLEEVLESSKFQEWTECRETLTVKPVLVDILSRYQELAHSIGVTIEN
                     QLTDATRVVMSLRALDKVLTNLISNAIKYSDKNGRVIISEQDGYLSIKNTCAPLSDQE
                     LEHLFDIFYHSQIVTDKDESSGLGLYIVNNILESYQMDYSFLPYEHGMEFKISL"
     gene            18908..19435
                     /locus_tag="VQU30_001442"
     CDS             18908..19435
                     /locus_tag="VQU30_001442"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000241939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isoprenylcysteine carboxyl methyltransferase
                     family protein"
                     /protein_id="HET2447535.1"
                     /translation="MVLAIILVTFFIRLIFLKRSIENEKRILSNGGKEFGVENTKRLT
                     MAHIVFYLSCLVEAMVHKTIFDGMGMVGLVLLIFSMLMLMLVIHLLGDIWTVKLMLVN
                     NHKYVDHILFRTVKHPNYFLNILPELIGLTLLSHAYVTFVLVFPVYAVILYRRIAEEE
                     KLLHEVIIPNGSIKR"
     gene            19514..>20733
                     /locus_tag="VQU30_001443"
     CDS             19514..>20733
                     /locus_tag="VQU30_001443"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000458116.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RICH domain-containing protein"
                     /protein_id="HET2447536.1"
                     /translation="MFASKSERKVHYSIRKFSIGVASVVVASLFLGGVVHAEGVRSGD
                     TPKVTSSGDEVESHLKKILSEIQTQLDRKRHAKTVALINKLQDIKRTYSYKLNVLEEK
                     PKAELTSKTKEELTAAFEQFKKDTLPTEPGKKVAEAEKKVAEAEKKAEDQKEEDRRNY
                     PTNTYKTLELEIAEFDVKVKEAELELLKEKAKKPLNEGTIKQAKEKVESKKAEATRLE
                     NIKTDRKKAEEEAKRKAAEEDKVKEKPAEQPQPAPAPQPEKPAPKPEKPAPAPKPENP
                     APKPEKPAPAPKPENPAEQPKAEKPADQQAEEDYARRSEEEYNRLTQQQPPKTEKPAQ
                     PSTPKTGWKQENGMWYFYNTDGSMATGWLQNNGSWYYLNSNGAMATGWLQNNGSWYYL
                     NANGSMATGWLQNNG"
BASE COUNT         6512 a         3431 c         4698 g         6092 t
ORIGIN      
        1 cggttacaat tcataaagtg ctgtagagag ataacgttca ccgttatctg gtgctagggc
       61 aaggactttt ttacctgtac ctaatttttt ggcaacctcg atggctccgt agatagctgc
      121 agctgaggaa atccctacaa ggaagccttc ttttccacca atttcacgtc cgagtgcaag
      181 agcgtcatct gatgttacac gaacgatacc atcataggct ttagtatcaa gtgtatcagg
      241 aataaatcca gctgagatac cttgaatttt gtgaggacca ggtttttcac cagatagaat
      301 agcagattca tctgcttcta ctgcaaaaac ttgaatgtta gaattttctg atttgagtgc
      361 atgagaaaca ccagaaatcg ttccaccagt acctactcca gcaacaaagg catctaatcc
      421 atctttaccg aaagcagcta gtatctcagc tcctgttgtt ctttcgtgta cttctggatt
      481 agctggattg tcaaattgaa gaggaaggaa accatcacgt tcagcagcga tttcttgagc
      541 cttagcaata gcacctttca ttccctcgct accaggagtt aggacgagtt cagcaccata
      601 agcttggata attttacgtc gttctacact catagtttca ggcataacga tgacgacttt
      661 atacccttta gcagcaccta cccatgaaag tccaataccg gtgtttccac ttgttgcttc
      721 aacaatagta gaaccaagtt tcagaatacc atcttgttca gctttttcaa tcatgctaag
      781 ggcaatacgg tcttttacag atgaaccagg attaaatgct tcaagcttta tatagacgtc
      841 tgcagcacct tctggcacga tgttgttaag tttaacaatc ggtgtttgac cgattaattc
      901 agtaatgttg ttataaatag acatatgaat acctctttgt ataagatatc tttagtataa
      961 cgctatccat accatttgta aaatatagaa atcctatcga agcgatagga tttctatata
     1021 tcatagatca aagtcattaa ttttcaagtg attgcgttca gttaattcta gtaaataggt
     1081 gtgaaggaaa acgatatcag gtttcgtttg aattgcttca ttttctagta tattttggta
     1141 cgcatctttt tattttgctc gctaaagtag ttgtgagaat gtcaacgaaa cgctgtatta
     1201 ttcattgttt acactaagtt tacagaaact tcaacctctc gtaaaccttg gtcagttaaa
     1261 gtgacttttc cattaaaaaa ctccacaagt gcagctttaa tagtttcttt ttcttcttta
     1321 tcaacataaa tcatcgtatc gacttgatct gtaaagtttg tatccagctc catgagatca
     1381 tgttctttaa ggaagttact gtactcttgg tactgagcat aagacatttg aatagcaatg
     1441 ccagcctgtt cttttatttc aataatacca atttctttga cagctaaggc gacactgccg
     1501 gcgtaagcac gaattagtcc tccagcgcct agtttaatac caccaaagta gcgtgtcacg
     1561 accacacaga cattggtgag attgtgattt tctagtaccc caagcatggg aacaccagca
     1621 gtaccactag gctcaccatc atcacttgta cgtttaattt cactacgttc tccaataata
     1681 aaggcagagc agttatgtgt cgctttgtag tgttcttttt tgatggcagt aatgaagtca
     1741 cgagcctctt cttcgctata aacacgcttg gcatggcaga taaagcgaga ttttttgatt
     1801 tcttcttgga cttggccgtc ctctttaatt gtcctaaatt ccatgattta attgtactaa
     1861 aaaataatct aaagtgctag tttttacgaa taaagaagta tgaaagtaaa tttagattat
     1921 ctcggtcgtt tatttactga gaatgaatta acagaagaag aacgtcagtt ggcggagaaa
     1981 cttccagcaa tgagaaagga gaaggggaaa cttttctgtc aacgttgtaa tagtactatt
     2041 ctagaagaat ggtatttgcc catcggtgct tactattgtc gagagtgctt gctgatgaag
     2101 cgagtcagaa gtgatcaaac tttatactat tttccgcagg aggattttcc gaagcaagat
     2161 gttctcaaat ggcgcggcca attaactcct tttcaagaga aggtgtcaga gggactgctt
     2221 caagcagtag acaagcaaaa gccaacctta gttcatgcgg taacaggagc tggaaagaca
     2281 gaaatgattt atcaagtagt ggctaaagtg atcaatgcgg gtggtgcagt gtgtttggct
     2341 agtcctcgca tagatgtttg tttggagctg tacaagcgcc tgcaacagga tttttcttgc
     2401 ggtatagctt tgctacatgg agaatcggaa ccttattttc gaacaccact agttgttgca
     2461 acaacccatc agttattgaa gttttatcaa gcttttgatt tgctgatagt ggatgaagta
     2521 gatgcttttc cttatgttga taatcccacg ctttaccacg ctgtcaagaa tagtgtaaag
     2581 gagaatggat tgagaatctt tttaacagcg acttcgacca atgagttaga taaaaaggtc
     2641 cgtttaggag aactaaaaag actgagttta ccgagacggt ttcatggaaa tccgttgatt
     2701 attccaaaac caatttggtt atcggatttt aatcgctact tagacaagaa tcgtttgtca
     2761 ccaaagttaa agtcctatat tgagaagcag agaaagacag cttatccgtt actcattttt
     2821 gcttcagaaa ttaagaaagg ggagcagtta gaagaaatct tacaggagca atttccaaat
     2881 gagaaaattg gctttgtatc ttctgtaaca gaggatcgat tagagcaagt acaagctttt
     2941 cgagatggag aactgacaat acttatcagt acgacaatct tggagcgtgg agttaccttc
     3001 ccttgtgtgg atgttttcgt aatagaggcc aatcatcgtt tgtttaccaa gtctagtttg
     3061 attcagattg gtggacgagt tggacgaagc atggatagac cgacaggaga tttgcttttc
     3121 ttccatgatg ggttaaatgc ttcaatcaag aaggcgatta aggaaattca gatgatgaat
     3181 aaggaggctg gtctatgaag tgcttgttat gtgggcagac tatgaagact gttttaactt
     3241 ttagtagtct cttacttctg aggaatgatg actcttgtct ttgttcagac tgtgattcta
     3301 cttttgaaag aattggggaa gagaactgtc caaattgtat gaaaacagag ttgtcaacaa
     3361 agtgtcaagc ttgtcaattt tggtgtaaag aaggagttga agtcagtcat agagcgattt
     3421 ttacttacaa tcaagctatg aaggattttt tcagtcggta taagtttgat ggagacttcc
     3481 tgttaagaaa agttttcgct tcatttttaa gtgaggagtt gaaaaagtac aaagagtatc
     3541 aatttgttgt aattccccta agtcctgata gatatgctaa cagaggattt aatcaggttg
     3601 agggcttggt agaggcagca ggctttgagt atctagattt attagagaaa agagaagaga
     3661 gagccagttc ttctaaaaat cgttcagagc gcttggggac agaacttcct ttctttatta
     3721 aaagtggagt cactattcct aaaaaaatcc tacttataga tgatatctat actacaggag
     3781 caactataaa tcgtgttaag aaactgttgg aagaagctgg tgctaaggat gtaaaaacat
     3841 tttcccttgt aagatgagga aaaaatttgc aaaaatagaa tgaaagcgtt ataataaaat
     3901 cataaaaaca aaaatgttta gaaagaaggt actcatatga ttaaatatag tatccgtggt
     3961 gaaaacctag aagtaacaga agcaattcgt gattatgtag tttctaaact cgaaaagatc
     4021 gaaaagtact tccaaccaga acaagagttg gatgcccgaa ttaacttaaa agtttatcgt
     4081 gaaaaaacgg ctaaagtgga agtaacgatt ccgcttggat ctattactct ccgcgcagaa
     4141 gatgtatctc aagatatgta tggttcaatt gaccttgtaa ctgataaaat tgaacgtcag
     4201 attcgtaaaa ataaaacaaa aatcgagcgt aaaaataaaa ataaggtagc aactggtcaa
     4261 ttatttacag atgctttggt ggaagattca aatattgtcc agtctaaagt tgttcgttca
     4321 aaacaaattg atttaaaacc aatggatttg gaagaagcaa ttctacaaat ggatttattg
     4381 gggcatgatt tctttatcta tgtggatgtt gaagatcaga caaccaatgt gatttatcgt
     4441 cgtgaggatg gcgaaattgg tttgttagag gttaaagaat cttaatttca atatgtgtaa
     4501 aggtaggttt actgaattgt aaactacctt tttcttataa ttgatagaat tactgattac
     4561 acttttaaaa agtcgctttt tgaggggtat tatggtataa tgggtgccaa gaggttttga
     4621 atgaaaaaat tttatgtaag tccaattttt cctattctag taggattgat tgcgtttgga
     4681 gtcttatcca ctttcattat ttttgttaat aataatctgt tgacggtttt aattttgttt
     4741 ctttttgtag gaggctatgt ttttttattt aagaaactga gagtgcatta tacaaggagt
     4801 gatgtagaac agatacagta tgtaaaccac caagcggaag aaagtttgac agctctattg
     4861 gaacagatgc ctgtaggtgt tatgaaattg aatttatctt ctggagaggt tgagtggttt
     4921 aatccctatg ctgaattgat tttgaccaag gaagatggtg attttgattt agaagctgtt
     4981 caaacgatta tcaaggcttc agtaggaaat ccgtctactt atgccaagct tggtgagaag
     5041 cgttatgctg ttcatatgga tgcttcttcc ggtgttttgt attttgtaga tgtatccagg
     5101 gaacaagcca taacagatga attggtaaca agtcgaccag tgattgggat tgtctctgtg
     5161 gataattatg atgatttgga ggatgcaact tctgagtcag atattagtca aatcaatagt
     5221 tttgtagcta attttatatc agagttttca gaaaaataca tgatgttttc tcgtcgggta
     5281 agtatggatc gattttatct atttactgac tacacggtgc ttgagggctt gatgaatgat
     5341 aaattttctg ttattgatgc tttcagagaa gagtcgaaac agagacagtt gcccttgacc
     5401 ttaagtatgg gattttctta tggcgatgga aatcatgatg agatagggaa agttgctttg
     5461 ctcaatttga acttggctga agtacgtggt ggcgaccagg tggttgttaa ggaaaacgac
     5521 gaaacgaaaa atccagttta ttttggtggt gggtctgctg cttcaatcaa gcgtacacgg
     5581 actcgtacgc gcgctatgat gacagctatt tcagataaga ttcggagtgt agatcaggtt
     5641 tttgtagtcg gtcacaaaaa tttagacatg gatgctttgg gctctgctgt aggtatgcag
     5701 ttgttcgcca gcaatgtgat tgaaaatagc tatgctcttt atgatgaaga acaaatgtct
     5761 ccagatattg aacgagctgt ttcattcata gaaaaagaag gagttacgaa gttgttgtct
     5821 gttaaggatg cattggggat ggtgaccaat cgttctttgt tgattcttgt agaccattca
     5881 aagacagcct taacattatc aaaagaattt tatgatttat ttacccaaac cattgttatt
     5941 gaccaccata gaagggatca ggattttcca gataatacgg tcattactta tatcgaaagt
     6001 ggtgcaagta gtgccagtga gttggtaacg gaattgattc agttccagaa ttctaagaaa
     6061 aatcgtttga gtcgtatgca agcaagtgtc ttgatggctg gtatgatgtt ggatactaaa
     6121 aatttcacct cgcgagtaac tagtcggaca tttgatgttg ctagctatct cagaacgcgc
     6181 ggaagtgata gtattgctat ccaggaaatc gctgcgacag attttgaaga atatcgtgag
     6241 gtcaatgaac ttattttaca ggggcgtaaa ttaggttcag atgtactaat agcagaggct
     6301 aaggacacga aatgctatga tacagttgtt attagtaagg cagcagatgc catgttagcc
     6361 atgtcaggta ttgaagcgag ttttgttctt gcgaagaata cacaaggatt tatctctatc
     6421 tcagctcgaa gtcgtagtaa actgaatgta caacggatta tggaagagtt aggcggtgga
     6481 ggccacttta atttggcagc agctcaaatt aaagatgtaa ccttgtcaga agcaggtgaa
     6541 aaactgacag aaattgtatt aaatgaaata aaggaaaagg agaaagaaga atgaaagtaa
     6601 tctttttagc agatgttaaa ggaaaaggta aaaaaggcga aattaaggaa gtaccaacag
     6661 ggtatgcgca aaactttctt atcaaaaaga atctagccaa agaagcgact gctcaagctg
     6721 taggtgaact tcgtggtaaa caaaaatcgg aagaaaaagc tcacgctgag atgattgcag
     6781 aaggaaaagc aattaaagca caacttgaag cagaagaaac tgttgtagaa tttgttgaaa
     6841 aagttggtcc agatggtcgt acctttggct ctattaccaa taagaagatt gcagaagaat
     6901 tgcaaaaaca atttggaatt aagattgata aacgtcatat tcaagtacaa gctccgattc
     6961 gagcggttgg tttgattgat gtgccagtga aaatctatca agatatcaca agtgtaatca
     7021 atcttcgtgt gaaagaagga taagtttaca ccttcttgac aagattgtaa aaggaaggga
     7081 agtctgatgg cagaagtaga agagttacga gtacaacctc aagatatctt agctgagcaa
     7141 tccgttttag gggctatctt tattgatgag agtaaacttg tttttgtgcg agaatacatt
     7201 gagtctcggg acttttttaa gtatgcccat cgtttgattt tccaagccat ggtcgattta
     7261 tccgatcgtg gtgatgccat agatgcaaca acggttcgta ctatccttga taatcaaggt
     7321 gatttacaga atattggtgg cttgtcttac ttggttgaga ttgttaattc tgtgccaact
     7381 tctgctaatg cggagtatta tgctaagatt gttgcagaaa aagcaatgct acgtcgttta
     7441 attgccaagt tgacagagtc tgtcaaccaa gcttacgaag cgtcacaacc agctgatgaa
     7501 attattgctc aggcagaaaa agggctgatt gatgtcagtg aaaatgcaaa tcgaagcggg
     7561 tttaagaaca ttcgagatgt gttgaatctc aactttggaa atctggaagc tcgctcgcaa
     7621 caaacgaccg atattacagg tattgcgaca ggttatcgtg atttggatca tatgacaaca
     7681 ggacttcatg aggaggagtt gattatctta gcagctcgtc cagcagttgg taagacagca
     7741 tttgccttga atatcgctca gaacattggg actaagttgg acaaaacggt tgctattttt
     7801 tcactcgaaa tgggtgcgga aagcttggta gatcgtatgt tagctgcaga aggcttagtg
     7861 gagtcacatt ctatccgtac agggcaattg acagatgagg agtggcaaaa atatactatt
     7921 gctcagggta atctagctaa cgccagtatc tatatcgatg atacgccagg tattcggatt
     7981 acagagattc gttctcgttc tcgtaaattg gctcaagaaa ctggaaatct tggtttgatt
     8041 ttgatagact atttgcaact tatcacggga actggtcgag aaaatcgtca acaagaagtt
     8101 tctgaaattt ctcgtcagtt gaaaatacta gccaaggaat tgaaggttcc agtaatcgct
     8161 ctgagtcagc tttctcgtgg tgtagaacaa cgtcaggaca agagaccggt cttgtctgat
     8221 attcgtgaat ctgggtctat tgagcaggac gctgatatcg tagcttttct ctatcgcgat
     8281 gactactatg aacgtggtgg tgaagaagag gagggtatcc caaataataa ggtggaagtt
     8341 attatcgaga aaaaccgtag tggagctcgt ggaacagtgg aattgatttt ccaaaaagaa
     8401 tacaataaat tttcaagtat ctcaaagagg gaggcataag atgtcagatg catttacaga
     8461 tgtagccaag atgaaaaaaa tcaaagaaga aatcaaggca catgagggac aagtcgtaga
     8521 aatgactttg gagaatggtc gtaagcgcca aaaaaataga ttgggtaagc taattgaagt
     8581 ttatccatct ctatttattg tggagtttgg ggatgtggaa ggagataaac aagttaatgt
     8641 ttacgttgaa tcctttactt actcagatat tcttacagaa aagaatttga ttcattatct
     8701 tgactaaagt gagaaatttt ctcacttttt cttttttctc cgaataattt aggtgaaggc
     8761 aatcatcgct ttatattatt tttcaaggag gaagaatgaa aattttaccg tttatagcaa
     8821 gaggaacaag ttattacttg aagatgtcag ttaaaaagct tgttcctttt ttagtagtag
     8881 gattgatgct agcagctggt gatagtgtct atgcctattc cagaggaaat ggatcgattg
     8941 cgcgtgggga tgattatcct gcttattata aaaatgggag ccaggagatt gatcagtggc
     9001 gcatgtattc tcgtcagtgt acttcttttg tagcctttcg tttgagtaat gtcaatggtt
     9061 ttgaaattcc ggcagcttat ggaaatgcga atgaatgggg acatcgtgct cgtcgggaag
     9121 gttatcgtgt agataataca ccgacgattg gttccattac ttggtctact gcaggaactt
     9181 atggtcatgt tgcctgggtg tcaaatgtaa tgggagatca gattgagatt gaggaatata
     9241 actatggtta tacagaatcc tataataaac gagttataaa agcaaacacg atgacaggat
     9301 ttattcattt taaagatttg gatggtggca gtgttgggaa tagtcaatcc tcaacttcaa
     9361 caggcggaac tcattatttt aagaccaagt ctgctattaa aactgaaccc ctagttagtg
     9421 caactgtgat tgattactat tatcctggag agaaggttca ttatgatcaa attctcgaaa
     9481 aagacggcta caagtggttg agttatactg cctataatgg aagctatcgt tatgttcaat
     9541 tggaggctgt gaataaaaat cctctaggta attctgttct ttcttcaaca ggtggaactc
     9601 attattttaa gaccaagtct gctatcaaaa ctgaacccct agttagcgga actgtgattg
     9661 attactatta tcctggggag aaggttcatt atgatcagat acttgaaaaa gacggctaca
     9721 agtggttgag ttatactgcc tataatggaa gtcgtcgcta tatacagcta gagggagtga
     9781 cttcttcaca aaattatcag aatcaatcag gaaatatctc tagctatgga tccaataata
     9841 gttcaactgt cggttggaag aaaataaatg gtagttggta tcatttcaaa tcaaatggtt
     9901 ctaaatcaac aggatggctg aaagacggtt ctagctggta ttatttgaaa ttatctggtg
     9961 aaatgcagac aggatggtta aaggagaatg gctcgtggta ttatctgggt agttcagggg
    10021 caatgaaaac aggctggtac caggtctctg gtaagtggta ttattcttac tcttcaggcg
    10081 ccttagctgt taatacgacg gtggatggct acagagtaaa cagtgatgga gaacgagtat
    10141 agaaaattgg agtaggagaa atttcctgct cttttctgta agcagtttcc ttgacatttt
    10201 tcttattttg cgctatcata tatacatata atatatggga gtctgtgtac agtctgagag
    10261 gaagtgttaa acttcgaccg cacctgatct gggtaatgcc agcggaggga acgatactta
    10321 gtctaatttt gcaccttttc catgtatggt aaaggttttt ctttttttta aaaggaaaac
    10381 gagaagagga ggttcttatg aaagcaagca ttgccttgca agttttaccc ctagcacagg
    10441 ggattgatcg gatagctgtt attgatcagg tcattgctta tctgcaaact caagaagtga
    10501 cgatggtagt gacaccattt gaaacggtct tggaagggga gtttgatgag cttatgcgca
    10561 ttctaaaaga agcgctggaa gtggcagggc aggaggcaga caatgtcttt gccaatgtca
    10621 aaataaatgt aggagagatt ttaagtattg atgagaaact tgaaaagtat actgagacga
    10681 cacattagtc tattgggctt tctcggagta ttgtcaatct ggcagttagc aggttttctt
    10741 aaacttctcc ccaagtttat cctgccgaca cctcttgaaa ttctccagcc ctttgttcgt
    10801 gacagagaat ttctctggca ccatagctgg gcgaccttga gagtggcttt actggggctg
    10861 attttgggag ttttgattgc ctgtcttatg gctgtgctca tggatagttt gacttggctc
    10921 aatgacctga tttaccctat gatggtggtc attcagacca ttccgaccat tgccatagct
    10981 cctatcctgg tcttgtggct gggttatggg attttgccca agattgtctt gattatctta
    11041 acaacaacct ttcccatcat cgttagtatt ttggacggtt ttaggcattg tgacaaggat
    11101 atgctgactt tgtttagtct gatgcgagca aacccttggc aaatcctgtg gcattttaaa
    11161 atcccggtta gcctgcctta cttttatgca ggtctgaggg tcagtgtctc ctacgccttt
    11221 atcacaactg tggtatctga gtggttggga ggttttgaag gtcttggtgt ttatatgatt
    11281 cagtctaaaa aactgtttca gtatgatacc atgtttgcca ttattattct ggtgtcgatt
    11341 atcagtcttt tgggtatgaa gctggtcgat atcagtgaaa aatatgtgat taaatggaaa
    11401 cgtacttaaa atagagcgtt tttgaaaaag aaaagaggaa atcaaaatga agaaaacatg
    11461 gaaagtgttt ttaacgcttg taacagctct tgtagctgtt gtgcttgtgg cctgtggtca
    11521 aggaactgct tctaaagaca acaaagaggc agaacttaag aaggttgact ttatcctaga
    11581 ctggacacca aataccaacc acacagggct ttatgttgcc aaggaaaaag gttatttcaa
    11641 agaagctgga gtggatgttg atttgaaatt gccaccagaa gaaagttctt ctgacttggt
    11701 tatcaacgga aaggcaccat ttgcagtgta tttccaagac tacatggcta agaaattgga
    11761 aaaaggagca ggaatcactg ccgttgcagc tattgttgaa cacaatacat caggaatcat
    11821 ctctcgtaaa tctgataatg taagcagtcc aaaagacttg gttggtaaga aatatgggac
    11881 atggaatgac ccaactgaac ttgctatgtt gaaaaccttg gtagaatctc aaggtggaga
    11941 ctttgagaag gttgaaaaag taccaaataa cgactcaaac tcaatcacac cgattgccaa
    12001 tggcgtcttt gatactgctt ggatttacta cggttgggat ggtatccttg ctaaatctca
    12061 aggtgtagat gctaacttca tgtacttgaa agactatgtc aaggagtttg actactattc
    12121 accagttatc atcgcaaaca acgactatct gaaagataac aaagaagaag ctcgcaaagt
    12181 catccaagcc atcaaaaaag gctaccaata tgccatggaa catccagaag aagctgcaga
    12241 tattctcatc aagaatgcac ctgaactcaa ggaaaaacgt gactttgtca tcgaatctca
    12301 aaaatacttg tcaaaagaat acgcaagcga caaggaaaaa tggggtcaat ttgacgcagc
    12361 tcgctggaat gctttctata aatgggataa agaaaatggt atccttaaag aagacttgac
    12421 agacaaaggc ttcaccaacg aatttgtgaa ataatgacag aaattagact agagcatgtc
    12481 agttatgcct atggtcagga gaggatttta gaggatatca acctacaggt gacttcaggc
    12541 gaagtggttt ccattctagg cccaagtggt gttggaaaga ccaccctctt taatctaatc
    12601 gctgggattt tagaagttca gtcagggaga attgtccttg atggtgaaga aaatcccaag
    12661 gggcgcgtga gttatatgtt gcaaaaggat ctgctcttgg agcacaagac ggtgcttgga
    12721 aatatcattc tgcccctctt gattcaaaag gtggataagg cagaagctat ttcccgagcg
    12781 gataaaattc ttgcgacctt ccagctgaca gctgtaagag acaagtatcc tcatgaactt
    12841 agcggtggga tgcgccagcg tgtagcctta ctccggacct acctttttgg gcacaagctc
    12901 tttctcttag atgaggcctt tagcgccttg gatgagatga caaagatgga actccacgct
    12961 tggtatcttg agattcacaa acagttgcag ctaacaaccc tgatcatcac gcatagtatt
    13021 gaggaggccc tcaatctcag cgaccgtatc tatatcttga aaaatcgccc tgggcagatt
    13081 gtttcagaaa ttaaactaga ttggtctgaa gatgaggaca aggaagtcca aaagattgcc
    13141 tacaaacgtc aaatcttggc agaattaggc ttagataagt agaaaaatag ggagttggtg
    13201 aagattatcc tttaccagcg ccctttttct tttaaaaatg agaaaatttc ggtataatag
    13261 tcaaacaagg tcaaggttta aagagagagg tgggtttgtt atgagattta aaaatacatc
    13321 ggatcatatt gaggcctaca tcaaggcgat tttagatcaa tctggtatcg tggagttgca
    13381 acggagtcag ttggcagata cctttcaggt tgttcctagt cagattaact acgtgatcaa
    13441 gacacgcttt acggaaagta gaggctactt ggttgaaagt aagcgtggtg gcggaggcta
    13501 cattcgtata ggacggattg agttttctag tcatcatgaa atgctccggg agctgcttta
    13561 ctcgattggt gagcgagtca gtcaagaaat ttatgaggat attctccagc ttttggttga
    13621 gcaggaattg atgaccaagc aggagatgaa tttgctagaa tcagtagctt tggatcgcgt
    13681 tttaggagaa gaagctccag ttgttcgagc aaacatgcta cgtcaggtca tacaagaggt
    13741 agatagaaaa gggaagtaag atgaactatt caaaagcatt gaatgaatgt atcgaaagtg
    13801 cctacatggt tgctggacat tttggagctc gttatctaga gtcgtggcac ttgttgattg
    13861 ccatgtctaa tcacagttat agtgtagcag gggcaacttt aaatgattat ccgtatgaga
    13921 tggaccgttt agaagaggtg gctttggaac tgactgaaac ggactatagc caggatgaaa
    13981 cctttatgga attgccgttc tcccgtcgtt tgcaggttct ttttgatgaa gcagagtatg
    14041 tagcgtcagt ggtccatgct aaggtactag ggacagagca cgtcctctat gcgattttgc
    14101 atgatggcaa tgccttggcg actcgtatct tggagagggc tggtttttct tatgaagaca
    14161 agaaagatca ggtcaagatt gctgctcttc gtcgaaattt agaagaacgg gcaggctgga
    14221 ctcgtgaaga tctcaaggct ttacgccaac gccatcgtac tgtggctgac aaacaaaatt
    14281 ctatggccaa tatgatgggc atgccgcaga ctcctagtgg tggtctcgag gactatacgc
    14341 atgatttgac agagcaagcg cgttctggca agttagaacc agtcatcggt cgggacaagg
    14401 aaatctcacg tatgattcaa atcttgagcc gtaagactaa gaacaaccct gtcttggttg
    14461 gggatgctgg tgtcgggaaa acagctctgg tgcttggtct tgctcagcgt attgccagtg
    14521 gtgatgtgcc tgcggaaatg gctaagatgc gcgtgttaga acttgatttg atgaatgtcg
    14581 ttgcagggac acgcttccgt ggtgactttg aagaacgcat gaataatatc atcaaggata
    14641 ttgaagaaga tggccaagtc atcctcttta tcgatgaact ccacaccatc atgggttctg
    14701 gtagcgggat tgattcgact ctggatgcgg ccaatatctt gaaaccagcc ttggcgcgtg
    14761 gagctttgag aacggttggt gccaccactc aggaagaata tcaaaaacat atcgaaaaag
    14821 atgcggctct ttctcgtcgt ttcgctaaag tgacgattga agaaccaagt gtggcagata
    14881 gtatgactat tttacaaggt ttgaaggcga cttatgagaa acatcaccgt gtacaaatca
    14941 cagatgaagc ggttgaaaca gcggttaaga tggctcatcg ttatttaacc agtcgtcact
    15001 tgccagactc tgctatcgac ctcttggacg aagcagcagc aacagtgcaa aataaggtaa
    15061 agtatgtaaa agcagacgat tcagatttga gtccagctga taaggccctg atggatggca
    15121 agtggaaaca ggcagcccag ctaatcgcaa aagaagagga agtacctgtc tacaaagact
    15181 tggtgacaga gtctgatatt ttgaccacct tgagtcgctt gtcaggaatc ccagttcaaa
    15241 aactgactca aacggatgct aagaagtatc taaatcttga agcagaactc cataaacgtg
    15301 tcatcggtca agatcaagct gtttcaagca ttagtcgtgc gattcgccgt aatcagtcag
    15361 gaattcgcag tcacaagcgt ccgatcggtt cctttatgtt cctaggaccc acaggtgtcg
    15421 gtaagaccga gttggccaag gctttggcag aagttctctt tgatgacgaa tcagccctta
    15481 tccgctttga tatgagtgag tatatggaga aattcgcagc cagccgtcta aatggagctc
    15541 ctccaggcta tgtgggttac gaagaaggtg gagagttgac agagaaggtt cgcaataaac
    15601 cctattccgt tctcctcttt gatgaggtag agaaggccca cccagatatt tttaatgttc
    15661 tcttgcaggt tctggatgac ggtgttttga cagatagcaa gggacgcaag gtcgattttt
    15721 caaataccat tatcattatg acatcgaacc taggtgcgac tgcccttcgt gatgataaga
    15781 ctgttggttt tggggctaag gatattcgtt ttgaccagga aaatatggaa aaacgcatgt
    15841 ttgaagaact gaaaaaagct tatagaccgg aattcatcaa ccgtattgat gagaaggtgg
    15901 tcttccatag cctatctagt gaccatatgc aggaagtggt gaagattatg gtcaagcctt
    15961 tagtggcaag tttggctgaa aaaggcattg acttgaaatt acaagcttca gctctgaaat
    16021 tgttagcaaa tcaaggatat gacccagaga tgggagctcg cccacttcgc agaaccctgc
    16081 aaacagaagt ggaggacaag ttggcagaac ttcttcttaa gggagattta gtggcaggca
    16141 gcacacttaa gattggtgtc aaagcaggcc agttaaaatt tgatattgca taaaagaata
    16201 aaagtatcag catctgacca taagtcacag tggagtgaaa ctcaatgaaa atcaaagagc
    16261 aaactaggca gctagccgca ggttgctcaa aacactggtt tgaggttgca gatagagctg
    16321 acgtggtttg aagagatttt cgaagagtat gaaactaaaa cctatagctt ctaaacgatc
    16381 cgtggttttc accattcaac acaaaattca tatgtttatt accctccgtc gtatttgtct
    16441 tagagcgtgt gtagtagaaa aagagcagtc ttatctgaaa tttttattct ttcaaaagag
    16501 acctgtttct tttttgcatg tcaaatccgt tctagctggt atttgaaaaa tcaaactaat
    16561 attcaatgaa aatcaaagaa caaactaggc agctagccac aggttgctca aaacactgtt
    16621 ttgaggttgt agatagagct gacgtagttt gaagagattt tcgaagagta taagctgcaa
    16681 gatgaatgat tttcttgtat tgacgttgtt gttgacaaaa agtagcggat aaatgaaatc
    16741 cattccatta tcatagatga taggctggta ggaaattttc aaatagcata caggaaatag
    16801 atgtatggag ttctggtagt agaaagggag agagatgaac attttagttg cagatgacga
    16861 ggaaatgatt agagaaggaa ttgcagcatt tctgacagaa gagggttatc atgtcattat
    16921 ggctaaggat ggacaagagg tcttggaaaa atttcaagat ctccctatcc atctcatggt
    16981 attggattta atgatgccta ggaagagtgg ttttgaagtg ttaaaagaaa tcaatcaaaa
    17041 gcacgatatt cctgtcatcg tcttgagtgc tctgggagat gaaactactc agtcacaggt
    17101 atttgatctc tatgctgatg atcatgtgac aaaacctttt tctttggtac tgcttgtcaa
    17161 gcgtattaag gcgcttatca gacgttacta cgtcatagag gatatttggc gatatcagga
    17221 tgtaacagtg gattttacct cttacaaagc acattataaa aatgaagaaa ttgatctcaa
    17281 accaaaggaa ttactggtac taaagtgttt gattcagcat aaaaatcaag ttttaagtag
    17341 agagcagata ttggaagaaa tttcaaaaga tgtagctgat ttaccttgtg atagggtcgt
    17401 tgatgtctat attcgtactc ttcgcaaaaa attagcttta gattgtatcg tgactgtgaa
    17461 aaatgttggg tataagatta gcttatgata aaaaatccta aattattaac caagtctttt
    17521 ttaagaagtt ttgcaattct aggtggtgtt ggtctagtca ttcatatagc tatttatttg
    17581 acctttcctt tttattatat tcaactggag ggggaaaagt ttaatgagag cgcaagagtg
    17641 tttacggagt atttaaagac taagacatct gatgaaattc caagcttact ccagtcttat
    17701 tcaaagtcct tgaccatatc tgctcacctt aaaagagata ttgtagataa gcgactccct
    17761 cttgtgcatg acttggatat taaagatgga aagctatcaa attatatcgt gatgttagat
    17821 atgtctgtta gtacagcaga tggtaaacag gtaacagtgc aatttgttca cggggtggat
    17881 gtctacaaag aagcaaagaa tattttgttt ttgtatcttc catatacatt tttggttaca
    17941 attgcttttt cctttgtttt ttcttatttt tatactaaac gcttgctcaa tcctcttttt
    18001 tacatttcag aagtgactag taaaatgcaa gatttggatg acaatattcg ttttgatgaa
    18061 agtaggaaag atgaagttgg tgaagttgga gaagttggaa aacagattaa tggtatgtat
    18121 gagcacttgt tgaaggttat tcatgagttg gaaagtcgta atgagcaaat tgtaaaattg
    18181 caaaatcaaa aggtttcctt tgtccgtgga gcatcacatg agttgaaaac ccctttagcc
    18241 agtcttagaa ttatcctaga gaatatgcag cataatattg gagattacaa agatcatcca
    18301 aaatatattg caaagagtat aaataagatt gaccagatga gccacttatt ggaagaagta
    18361 ctggagtctt ctaaattcca agagtggaca gagtgtcgtg agaccttgac tgttaagcca
    18421 gttttagtag atattttatc acgttatcaa gaattagctc attcaatagg tgttacaatt
    18481 gaaaatcaat tgacagatgc taccagggtc gtcatgagtc ttagggcatt ggataaggtt
    18541 ttgacaaacc tgattagtaa tgcaattaaa tattcagata aaaatgggcg cgtaatcata
    18601 tccgagcaag atggctatct ctctatcaaa aatacatgtg cgcctctaag tgaccaagaa
    18661 ctagaacatt tatttgatat attctatcat tctcaaatcg tgacagataa ggatgaaagt
    18721 tccggtttgg gtctttacat tgtgaataat attttagaaa gctatcaaat ggactatagt
    18781 tttctccctt atgaacacgg tatggaattt aagattagct tgtagacaga ttagtttttt
    18841 attaaagttc atatagggtt aacataagtg tgttattctt tgtgtagata aaagaaagga
    18901 tactaatatg gtattagcga ttattttagt aacattcttt attcgattga tttttttaaa
    18961 gcgttcgata gagaatgaga aacgaatcct tagcaatggc gggaaagaat ttggagttga
    19021 gaatacaaaa cgattaacta tggctcatat tgttttttat ctctcttgct tggttgaggc
    19081 aatggtgcac aagacaattt ttgatggcat gggcatggtt ggtttagtct tgcttatttt
    19141 ttctatgctg atgttaatgt tggtgattca cttgttggga gatatttgga cagtgaagct
    19201 tatgcttgtc aataatcaca aatatgtaga tcatatcttg tttaggacag taaaacatcc
    19261 taattacttt ttaaatattc ttcctgagtt gattggcttg accttgttga gtcatgctta
    19321 tgtgactttt gttttagttt ttccagttta tgcagttatt ttgtatcgac gaatagctga
    19381 agaggaaaag ctattacatg aagttataat cccaaatgga agcataaaga gataaataca
    19441 aaattcgatt tatatacagt tcatattgaa gtgatatagt aaggttaaag aaaaaatata
    19501 gaaggaaata aacatgtttg catcaaaaag cgaaagaaaa gtacattatt caattcgtaa
    19561 atttagtatt ggagtagcta gtgtagtagt tgctagcttg ttcttaggag gagtagttca
    19621 tgcagaaggg gttagaagtg gggatacccc caaggttaca tctagtgggg atgaagtcga
    19681 gtcgcatcta aaaaaaatat tgagtgagat ccaaacacaa ttagatagaa aacgacatgc
    19741 caaaactgta gcgctaatta acaagttgca agacattaag agaacgtatt cgtataaatt
    19801 aaatgtttta gaagagaagc cgaaagctga gttgacgtca aaaacaaaag aagagttaac
    19861 cgcagctttt gagcaattta aaaaagatac attaccaaca gaaccaggaa aaaaggtagc
    19921 agaagctgag aagaaggttg cagaagctga gaaaaaagcc gaggatcaaa aagaagaaga
    19981 tcgtcgtaac tacccaacca atacttacaa aacgcttgaa cttgaaattg ctgagttcga
    20041 tgtgaaagtt aaagaagcgg agcttgaact attaaaagag aaagctaaga aacctttaaa
    20101 cgagggcaca attaagcaag caaaagagaa agttgagagt aaaaaagctg aggctacaag
    20161 gttagaaaac atcaagacag atcgtaaaaa agcagaagaa gaagctaaac gaaaagcagc
    20221 agaagaagat aaagttaaag aaaaaccagc tgaacaacca caaccagcgc cggctcctca
    20281 accagaaaaa ccagctccaa aaccagaaaa accagctcca gctccaaaac cagagaatcc
    20341 agctccaaaa ccagaaaaac cagctccagc tccaaaacca gagaatccag ctgaacaacc
    20401 aaaagcagaa aaaccagctg atcaacaagc tgaagaagac tatgctcgta gatcagaaga
    20461 agaatataat cgcttgactc aacagcaacc gccaaaaact gaaaaaccag cacaaccatc
    20521 tactccaaaa acaggctgga aacaagaaaa cggtatgtgg tacttctaca atactgatgg
    20581 ttcaatggcg acaggatggc tccaaaacaa tggctcatgg tactacctca acagcaatgg
    20641 cgctatggcg acaggatggc tccaaaacaa tggttcatgg tactatctaa acgctaatgg
    20701 ttcaatggca acaggatggc tccaaaacaa tgg
//
LOCUS       DAVBBO010000040        20672 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ST1
            SAMEA2066453-rid20184263.denovo.040, whole genome shotgun sequence.
ACCESSION   DAVBBO010000040 DAVBBO010000000
VERSION     DAVBBO010000040.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2066453
            Sequence Read Archive: ERR351777
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 20672)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 20672)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980402.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980402.1
            Genome Coverage       :: 176x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:17:33
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,141
            CDSs (total)                      :: 2,104
            Genes (coding)                    :: 1,953
            CDSs (with protein)               :: 1,953
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 16S)
            partial rRNAs                     :: 1 (23S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 151
            CDSs (without protein)            :: 151
            Pseudo Genes (ambiguous residues) :: 0 of 151
            Pseudo Genes (frameshifted)       :: 73 of 151
            Pseudo Genes (incomplete)         :: 76 of 151
            Pseudo Genes (internal stop)      :: 40 of 151
            Pseudo Genes (multiple problems)  :: 32 of 151
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..20672
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2066453-rid20184263.denovo.040"
                     /strain="ST1"
                     /db_xref="taxon:1313"
     gene            complement(<1..187)
                     /locus_tag="VQU30_001444"
     CDS             complement(<1..187)
                     /locus_tag="VQU30_001444"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019770457.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HET2447537.1"
                     /translation="MLYVGIDIAKNKHDVTALNVPGKTVLKPLTFSNNKAGFELLDLS
                     LRQLNQDCLIALENTGHY"
     gene            442..1287
                     /locus_tag="VQU30_001445"
     CDS             442..1287
                     /locus_tag="VQU30_001445"
                     /EC_number="3.6.1.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000273482.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="undecaprenyl-diphosphate phosphatase"
                     /protein_id="HET2447538.1"
                     /translation="MYLIEILKSIFFGIVEGITEWLPISSTGHLILAEEFIQYQNQNE
                     AFMSMFNVVIQLGAILAVMVIYFNKLNPFKPTKDKQEVRKTWRLWLKVLIATLPLLGV
                     FKFDDWFDTHFHNMVSVALMLIIYGVAFIYLEKRNKARAIEPSVTELDKLPYTTAFYI
                     GLFQVLALLPGTSRSGATIVGGLLNGTSRSVVTEFTFYLGIPVMFGASALKIFKFVKA
                     GELLSFGQLFLLLVAMGVAFAVSMVAIRFLTSYVKKHDFTLFGKYRIVLGSVLLLYSF
                     VRLFV"
     gene            complement(1434..2495)
                     /gene="dinB"
                     /locus_tag="VQU30_001446"
     CDS             complement(1434..2495)
                     /gene="dinB"
                     /locus_tag="VQU30_001446"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000904550.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase IV"
                     /protein_id="HET2447539.1"
                     /translation="MLIFPLLNDLSRKIIHIDMDAFFAAVEIRDNPKLRGKPVIIGSD
                     PRQTGGRGVVSTCSYEARAFGVHSAMSSKEAYERCPQAVFISGNYEKYKSVGLQIRAI
                     FKRYTDLIEPMSIDEAYLDVTENKLGIKSAVKIARLIQKDIWQELHLTASAGVSYNKF
                     LAKMASDYQKPHGLTVILPEQAEDFLKQMDISKFHGVGKKTVERLHQMGVFTGADLLE
                     VPEVTLIDRFGRLGYDLYRKARGIHNSPVKSNRIRKSIGKEKTYGKILLAEEDIKKEL
                     TLLSEKVALNLHQQEKAGKIVILKIRYEDFSTLTKRKSLAQKTQDASQISQIALQLYE
                     ELSKKERGVRLLGITMTGF"
     gene            2843..5167
                     /gene="pflB"
                     /locus_tag="VQU30_001447"
     CDS             2843..5167
                     /gene="pflB"
                     /locus_tag="VQU30_001447"
                     /EC_number="2.3.1.54"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399021.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate C-acetyltransferase"
                     /protein_id="HET2447540.1"
                     /translation="MVVKTVVEAQDIFDKAWEGFKGVDWKEKASVSRFVQANYTPYDG
                     DESFLAGPTERSLHIKKIVEETKAHYEETRFPMDTRPTSIADIPAGFIDKENEVIFGI
                     QNDELFKLNFMPKGGIRMAETTLKENGYEPDPAVHEIFTKYVTTVNDGIFRAYTSNIR
                     RARHAHTVTGLPDAYSRGRIIGVYARLALYGADYLMQEKVNDWNAIKEIDEETIRLRE
                     EVNLQYQALQQVVRLGDLYGVDVRKPAMNVKEAIQWVNIAFMAVCRVINGAATSLGRV
                     PIVLDIFAERDLARGTFTESEIQEFVDDFVMKLRTVKFARTKAYDQLYSGDPTFITTS
                     MAGMGNDGRHRVTKMDYRFLNTLDNIGNSPEPNLTVLWTDKLPYNFRRYCMHMSHKHS
                     SIQYEGVTTMAKDGYGEMSCISCCVSPLDPENEEQRHNIQYFGARVNVLKALLTGLNG
                     GYDDVHKDYKVFDIEPIRDEVLEFESVKANFEKSLDWLTDTYVDALNIIHYMTDRYNY
                     EAVQMAFLPTKQRANMGFGICGFANTVDTLSAIKYATVKPIRDEDGYIYDYETIGDYP
                     RWGEDDPRSNELAEWLIEAYTTRLRSHKLYKDAEATVSLLTITSNVAYSKQTGNSPVH
                     KGVYLNEDGSVNLSKLEFFSPGANPSNKAKGGWLQNLNSLSSLDFSYAADGISLTTQV
                     SPRALGKTRDEQVDNLVTILDGYFENGGQHVNLNVMDLNDVYEKIMSGEDVIVRISGY
                     CVNTKYLTPEQKTELTQRVFHEVLSMDDALDALS"
     gene            complement(5534..5752)
                     /locus_tag="VQU30_001448"
     CDS             complement(5534..5752)
                     /locus_tag="VQU30_001448"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001849851.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2447541.1"
                     /translation="MMSIREQDLQDIGAIIKYKNFHSPFDTFKYLKDMGFDTIDLSVL
                     LEGFSYAYGMDWLEKFFKENQDKLREFY"
     gene            complement(5848..6086)
                     /locus_tag="VQU30_001449"
                     /pseudo
     CDS             complement(5848..6086)
                     /locus_tag="VQU30_001449"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397100.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(6079..6363)
                     /locus_tag="VQU30_001450"
     CDS             complement(6079..6363)
                     /locus_tag="VQU30_001450"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002923859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2447542.1"
                     /translation="MDWYDYMIQASKQSQFNASHWFRYLRKVIFEDYSYLTNQDVEKL
                     LDSKELTRFQKISLKYAFQEHTPTHKYVISLNKPAKLTNVQKLMEKYKHG"
     gene            complement(6975..7145)
                     /locus_tag="VQU30_001451"
     CDS             complement(6975..7145)
                     /locus_tag="VQU30_001451"
                     /inference="COORDINATES: protein motif:HMM:NF024172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HET2447543.1"
                     /translation="MTKQVPKFTKDTAQLYTCKWLLYNKVTKMYDHTVVNHSVREYIT
                     DSISTNTIEETG"
     gene            complement(7795..9018)
                     /locus_tag="VQU30_001452"
     CDS             complement(7795..9018)
                     /locus_tag="VQU30_001452"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000628995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family transcriptional regulator"
                     /protein_id="HET2447544.1"
                     /translation="MITKQSAFLQNRATILEFLYRNPATSRTDIVNETGLTPATTTNI
                     IKELSEQSLIYETGDEFSEFSGSGRRRKTISITDNIPYVVGGIEINVLGIFLSLCDLQ
                     GKTLFETEILNEDYPISEINSTITNMIKTAIEYVPLETKLLGFGLSIPGHYNKDSGSI
                     ITNNPIWESFNLLNVIKRFNFPFIVKNNIDCMAIGQYLFNPHNTPDNFIFLHAGLGIY
                     TSFFTKEKIGASKNPYIGEIGHTIVELNGQYCECGKKGCLQTYISDAWLIKHAQLLFK
                     NSQLTVLKSLVKTEKDIHLDTLLTAYNLGDSALRQQIDKGVNLLATSIANLLLINPAD
                     KIYINSQLLNYQPFTHEVRDKIQDQLHFVPFTRNIEIEILPYNKHRGSIGACALAIVA
                     FFIEHSNVLQDIISP"
     gene            9186..10508
                     /locus_tag="VQU30_001453"
     CDS             9186..10508
                     /locus_tag="VQU30_001453"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001059752.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HET2447545.1"
                     /translation="MNNILAFLETKVAPFGEKVGNQRHLKAIREGFMMAMPLILVGSL
                     FLILISWPQEDFTNWLNSVGLLSILTTMNQSTVAIISLVACFGIAYRLSEGYGTDGPS
                     AGIIALSSFVLMAPRFSSMVYDKNGEQVKQLFGGAIPFSSLNASSLFMAITIGLVTAE
                     IYRMFIQRGITIKMPSGVPDVVSKSFSALLPGFTTFVLWALVLKGLEAAGVAGGLNGL
                     LGAIVGTPLKLIAGTLPGMILCVIVNSFFWFCGVNGGQVLNAFVDPVWLQFTTENQEA
                     VAAGQTLQHIITLPFKDLFVFIGGGGATIGLAICLFLFSKSRANKTLGKLAIIPSIFN
                     INTAILFTFPTVLNPIMLIPFIATPTINALITYVSMAVGLVPYTTGVILPWTMPPIIG
                     GFLATGASWRGALLQVVLILVSVAIYYPFFKIADKRNLEKEKATVGGK"
     gene            10510..12396
                     /locus_tag="VQU30_001454"
     CDS             10510..12396
                     /locus_tag="VQU30_001454"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000236922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4838 domain-containing protein"
                     /protein_id="HET2447546.1"
                     /translation="MVIRVFDQQKNTYSSFALEELSYYINRVFKTDIELVEEKEADIF
                     VGLVNKEDRKDHVLISLDKGKGRIESNTIVGLLIGIYRMFHEFGVVYTRPGRGHDFVP
                     ELRFEDFLDKELSIDETASYYHRGVCIEGADSFENILDFIDWLPKIGMNSFFIQFENP
                     YSFLKRWYEHEFNPYLNKEKFSNELVQELSDRLDKELQKRGLIHHRVGHGWTGEVLGY
                     SSKFGWESGLSISEEKKPYVAEINGKRELFNTAPILTSLDFSNPDVADKMVEIIKDYA
                     KKRPDVNYLHVWLSDARNNICECENCRQELVSDQYIRILNQLDRALTSEGLDTKICFL
                     LYHELLWAPQKEKLDNPERFTMMFAPITRTFEMSYADVDFDNSIPTPKPYLRNKIILP
                     NSLEENLSYLFEWQKTFKGDSFVYDYPLGRAHYGDLGYMKISQTIYRDVSYLSNLHLN
                     GYISCQELRAGFPHNFPNYVMGEMLWKKTRSYEELIEEYFSALYGSNWQSVVEYLEKL
                     SSYSSCDYFNAIGSRQNDVLANHYYIAYNLADNFLPIIEENISKLLNSQKDEWKQLSY
                     HREYVVKMAKALYLQATGKTRQAQDEWRNVLNYIRGHELLFQSNLDVYRVIEVAKNYA
                     GFHL"
     gene            12564..12908
                     /locus_tag="VQU30_001455"
     CDS             12564..12908
                     /locus_tag="VQU30_001455"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000836781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HET2447547.1"
                     /translation="MKSKEEINMLGFTIVAYAGDARSDLMDALAFARDGYFEQARELV
                     ESANDSIVSAHREQTNLLAEEASGDNFEVSFIMIHGQDTLMTTMLLYDQVKFFIDEYE
                     RIRKIEEHIGLQ"
     gene            12918..14330
                     /gene="lacG"
                     /locus_tag="VQU30_001456"
     CDS             12918..14330
                     /gene="lacG"
                     /locus_tag="VQU30_001456"
                     /EC_number="3.2.1.85"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000429433.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-galactosidase"
                     /protein_id="HET2447548.1"
                     /translation="MENLQVKALPKEFLLGAATAAYQVEGATRVDGKGTNMWDVYLQE
                     NSPFLPDPASDFYYRYEEDITLAAEHGLQALRLSISWVRIFPDIDGEPNILAVRYYHR
                     VFQSCLKHNVIPFVSLHHFDSPQKMLETGDWLNRENIDRFIRYARFCFQEFTEVKHWF
                     TINELMSLAAGQYIGGQFPPNHHFQLSEAIQANHNMLLAHALAVLEFHQLGIEGEIGC
                     IHALKPGYPIDGQKENILAAKRYDVYNNKFLLDGTFLGYYSEDTLFHLNQILEANNSS
                     FIIEDGDLEIMKRAAALNTMFGMNYYRSEFIREYKGENRQEFNSTGIKGQSSFKLNAL
                     GEFVKKPGIPTTDWDWNIYPQGLFDMLLRIKEEYPQHPVIYLTENGTALKEVKPEGEN
                     DIIDDSKRIRYIEQHLHKVLEARDRGVNIQGYFIWSLQDQFSWANGYNKRYGLFFVDY
                     ETQKRYIKKSALWVKGLKRN"
     gene            14400..16079
                     /locus_tag="VQU30_001457"
     CDS             14400..16079
                     /locus_tag="VQU30_001457"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000359733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HET2447549.1"
                     /translation="MDKLVAAIEKQQGKFEKISTNNYMIAIKDGFIATMPLIMFSSFL
                     MIIIMIPKNFGVELPSPAIAWMRKVYMLTMGVLGIIVSGTVAKSLAGNVNRKMPPGKV
                     INDTSAMLAAICGYLVLTVTLVVDEKTGSTSLSTNYLGSQGLITSFVSAFITVNVYRF
                     CIKRDITIHLPKEVPGAISQAFRDIFPFSFVLLISGLLDIVSRFSLDVPFAQVFQQLL
                     TPIFKGAESYPAMMLIWFMCALLWFVGIHGPSIVLPAVTALQLSNMEENAQLLANGQF
                     PYHSLTPNFGNYIAAIGGTGATFVVPFILIFFMRSKQLKSVGKATITPVLFAVNEPLL
                     FGMPVILNPYLFVPFLMTPPVNVFLGKVFIDFFGMNGFYIQLPWAFPGPLGLLIGTNF
                     QLISFVFLSLMLVVDILIYLPFCRAYDRQLLVKEDIASSNDIILEEDTSEIMPGEIDV
                     IKSKELKVLVLCAGSGTSAQLANAINEGAQLAEVRVIANSGAYGAHYDIMGVYDLIIL
                     APQVRSYYREMKVDAERLDIQIVATRGMEYIHLTKSPSKALQFVLEHYQAV"
     gene            complement(16205..17644)
                     /locus_tag="VQU30_001458"
     CDS             complement(16205..17644)
                     /locus_tag="VQU30_001458"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519662.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TrkH family potassium uptake protein"
                     /protein_id="HET2447550.1"
                     /translation="MNKSMIRYLLSKLLLIEAVLLLVPVAIAVYYRESSQVFTALFST
                     IGILVLLGGSGSLQKPKNQRIYAKEGVLIVALCWILWSFFGGLPFVFSGQIPSLIDAF
                     FEISSGFTTTGASILNDVSVLSRSLLFWRSFTHLIGGMGVLVFALAIMDNAKNSHLEV
                     MKAEVPGPVFGKVVSKLKNTAQILYLLYLALFSLFVIIYYLAGMPLYDSFVIAMGTAG
                     TGGFTVYNDGIAHYGSSLITYLVSIGVLVFGVNFNLYYYLMLRRIKAFFGDEELRAYL
                     VIVLVSTGLISLNTLYLYPGFSKSFEMTFFQVSNIITTTGFGYGDITNWPLFSQFILL
                     FLMAIGGSAGSTAGGLKIIRGLILSKIAKNQILSILSPHRVLTLHVNKTVIDKDTQHK
                     ILKYFVIYAMILLALIFIVSLDSNDFLVVTSAVFSCFNNIGPILGTTSSFSIFSPISK
                     ILLSFAMIAGRLEIYPILLLFMKRTWSKR"
     gene            complement(17648..18997)
                     /gene="trkA"
                     /locus_tag="VQU30_001459"
     CDS             complement(17648..18997)
                     /gene="trkA"
                     /locus_tag="VQU30_001459"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000691677.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Trk system potassium transporter TrkA"
                     /protein_id="HET2447551.1"
                     /translation="MKIILVGGGKVGFALCRSLVAEKHDVLLIEQDEAVLNHIVSRFD
                     IIGILGNGADFAILEQASVQDCDIFIALTEHDEVNMIAAVLAKKMGAKETIVRVRNPE
                     YSNSYFKEKNILGFSLIVNPELLAARAIANIIDFPNALSVERFAGGRVSLMEFVVKST
                     SGLCQMPISDFRKKFGNVIVCAIERDHQIIIPSGDMTVQDKDRIFVTGNRVDMILFHN
                     YFKSRAVKSLLIVGAGRIAYYLLGILKDSRIDTKVIEINPEIASFFSEKFPNLYIVQG
                     DGTAKDILLEESAQHYDAVATLTGVDEENLITSMFLDRVGVQKNITKVNRTSLLEIIN
                     APDFSSIITPKSIAVDTIMHFIRGRVNAQYSDLQAMHHLANGQIETLQFHIKEANKMT
                     AKPLSQLKLKKGVLIAAIIRKGKTIFPTGEDMLEVGDKLLVTTLLPNITKIYDLIAR"
     gene            19185..20033
                     /locus_tag="VQU30_001460"
     CDS             19185..20033
                     /locus_tag="VQU30_001460"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862942.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S-adenosyl-l-methionine hydroxide
                     adenosyltransferase family protein"
                     /protein_id="HET2447552.1"
                     /translation="MNNNLLVLQSDFGLVDGAVSAMIGVALEESPTLKIHHLTHDITP
                     YNIFEGSYRLFQTVDYWPEGTTFVSVVDPGVGSKRKSVVAKTAKNQYIVTPDNGTLSF
                     IKKHVGIVAIREISEVANRRQNTEHSYTFHGRDVYAYTGAKLASGHITFEEVGPELSV
                     EQIVELPVVATIIEDHLVKGAIDILDVRFGSLWTSITREEFYKLEPEFGDRFEVTIYH
                     ADMLVYQNQVVYGKSFADVRIGQPILYINSLYRLGLAINQGSFAKAYNVGVGSSWTIE
                     IKKIEG"
     gene            20048..20596
                     /locus_tag="VQU30_001461"
     CDS             20048..20596
                     /locus_tag="VQU30_001461"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000403170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF-type riboflavin transporter
                     substrate-binding protein"
                     /protein_id="HET2447553.1"
                     /translation="MEIKFTIKQVVAVGIGAALFVVIGMINIPTPVPNTSIQLQYAVQ
                     ALLSIIFGPIIGLLVGLIGHAIKDSLVGYGLWWTWIIASGLFGLVVGLFRKYVRVING
                     VFDWKDILIFNLIQLLANALVWGVLAPLGDVVIYQEAAEKVFAQGIVAGIANGVSVAI
                     AGTLLLLAYAGTQTRAGSLKKD"
BASE COUNT         6263 a         3513 c         4232 g         6664 t
ORIGIN      
        1 cataatgtcc ggtattttca agagcgatga gacagtcttg gttgagctgt cgaagagaca
       61 gatctaagag ttcaaaacca gctttattat ttgaaaaagt gagtggttta agaacagttt
      121 ttcctggaac attcaaggct gtaacatcgt gtttattttt agcgatatca atgcccacat
      181 aaagcatggg agtacctcca gatatagtat ttcaagtcta cttggttatc cacgaatttt
      241 ttgccttgtt accttagacg agatcaaacg tctatgcgtt atcaaactca ttaccaattg
      301 aaacaaaagc tgtggttaga gcctttcgga aatcgtcaag cgattggagg aaatgaacta
      361 atccacagtg gcttattcca agtataccac ttgggctttg gcagtagcta actgcgctaa
      421 ttataatata gggagtaatc tatgtatctt attgaaattt taaaatctat cttcttcggg
      481 attgttgaag gaattacgga atggttgccg atttccagta caggtcactt gattttagca
      541 gaggaattca tccaatacca aaatcaaaat gaagccttta tgtccatgtt taatgtcgtg
      601 attcagcttg gtgctatttt agcagttatg gtgatttatt ttaacaagct caatcctttt
      661 aaaccgacta aggacaaaca ggaagttcgt aagacttgga gactatggtt gaaggtcttg
      721 attgctactt tacctttact tggtgtcttt aaatttgatg attggtttga tacccacttc
      781 cataacatgg tttcagttgc tctcatgttg attatctacg gggttgcctt catctatttg
      841 gaaaagcgca ataaagcgcg tgctatcgag ccaagtgtaa cagagttgga caagcttcct
      901 tatacgaccg ctttctatat cggactcttc caagttcttg ctcttttacc agggactagc
      961 cgttcaggtg caacgattgt cggtggtttg ttaaatggaa ccagtcgttc agttgtgaca
     1021 gaatttacct tctatcttgg gattcctgtt atgtttggag ctagtgcctt aaagattttc
     1081 aaatttgtga aagccggaga actcttgagc tttgggcaat tgtttttgct cttggtcgcg
     1141 atgggagtag cttttgcggt cagcatggtg gctattcgct tcttgaccag ctatgtgaaa
     1201 aaacacgact tcaccctttt tggtaaatac cgtatcgtgc ttggtagtgt tttgctactt
     1261 tacagttttg tccgtttatt tgtataagaa aaaccttgaa ggggcaactc ttcaaggttt
     1321 tatactcttc gaaaatctct tcaaaccgcg tcagctttat ctgcaacctc aaaacagtgt
     1381 tttgagcagc ctgcggctag cctcctagtt tgctctttga ttttcattga gctttaaaat
     1441 ccagtcatgg taatccccaa taggcggaca cctctttctt tcttgcttaa ttcttcatag
     1501 agttgcaggg ctatttggct tatctgacta gcatcttgtg ttttttgagc aagacttttt
     1561 cgtttggtaa gagttgaaaa gtcctcgtag cggattttca aaatgacaat ttttccagct
     1621 ttttcttgtt gatgtagatt gagagcgact ttttctgata gaagagtcag ctcttttttg
     1681 atatcttcct cagcaaggag aatcttcccg taggttttct ccttgccgat tgatttacgg
     1741 atgcgattgg atttgactgg agagttgtga atgccacgag cctttcgata cagatcatag
     1801 cctagtctac caaaacggtc tattagggtt acctcaggaa cttcaagtaa atcagcacca
     1861 gtaaaaacgc ccatttgatg aagacgttct actgtctttt ttcctactcc atgaaatttg
     1921 gaaatatcca tttgtttgag aaaatcctca gcctgttcag gtagaatcac tgtcaaacca
     1981 tgtggttttt gataatcact cgccatttta gctaagaatt tgttgtaaga aacgcctgcg
     2041 gaagcagtta gatggagttc ttgccagata tctttttgaa tgaggcgagc aattttgacc
     2101 gctgacttga taccgagttt attttctgtc acatccaaat aggcttcgtc aatgctcatg
     2161 ggttcaatca aatctgtata gcgcttaaaa atagctcgaa tctggagtcc cacagacttg
     2221 tatttctcat aattccctga gataaagaca gcctggggac aacgttcata agcttccttg
     2281 gaactcatgg cagaatggac accaaaagct cttgcctcat aactacaggt agaaacgact
     2341 ccccgtccac ctgtttgccg agggtcgctt ccaataatga caggttttcc tctgagttta
     2401 ggattatccc tgatttccac tgcagcaaaa aaggcatcca tgtcaatatg gatgattttt
     2461 cttgacaaat catttaacaa aggaaaaatc aacatgccta gcaccttttt atactcttcg
     2521 aaaatctctt caaaccacgt cagctctatc tgcaacctca aaacagtgtt ttgagcaatc
     2581 tgcggctagc ttcctagttt gcttttcgat ttccattgag tgttactgct tattttcttt
     2641 tattataccc ttttttctga aaaaaagaaa aaaggacttt attttttcaa aaatataata
     2701 cagtttgaaa taaaatatag actgttttag aaaagaaagt gtaaaaatag ggaattttca
     2761 cttgttgaaa tcggttacta tatggtatac ttgtcttatg aatgtaacag atgactgtta
     2821 ctagaaaaaa gaggacatta atatggttgt taagacagtt gttgaagcac aagatatttt
     2881 tgacaaagct tgggaaggct tcaaaggcgt agattggaaa gaaaaagcaa gtgtatcacg
     2941 atttgtacaa gctaactaca caccttatga tggagacgaa agcttccttg caggaccaac
     3001 agagcgttca cttcacatca agaaaattgt agaagaaact aaagcacact acgaagaaac
     3061 tcgtttccca atggacactc gtccaacatc tatcgctgat atccctgctg gatttatcga
     3121 caaagaaaat gaagttatct tcggtatcca aaacgatgaa ctcttcaaat tgaacttcat
     3181 gccaaaaggt ggtatccgta tggctgaaac tactttgaaa gaaaatggat acgaaccaga
     3241 cccagctgtt cacgaaatct tcactaaata tgtaacaaca gttaacgacg gtattttccg
     3301 tgcctacact tcaaatattc gtcgcgctcg tcacgcacac actgtaactg gtcttccaga
     3361 tgcatactca cgcggacgta tcatcggtgt ttacgcacgt cttgctcttt acggtgcaga
     3421 ctacttgatg caagaaaaag taaatgactg gaatgcaatc aaagaaatcg atgaagaaac
     3481 aatccgtctt cgtgaagaag taaaccttca ataccaagca ttgcaacaag ttgttcgcct
     3541 gggtgacctt tacggggttg atgttcgcaa accagcgatg aacgtgaaag aagcaatcca
     3601 atgggttaac attgctttca tggctgtctg ccgtgtgatt aacggtgctg ctacatctct
     3661 aggtcgtgta ccaatcgtat tggacatctt tgcagaacgt gaccttgctc gtggtacatt
     3721 tactgaatca gaaatccaag aattcgttga tgatttcgtt atgaaacttc gtacagttaa
     3781 atttgctcgt acaaaagctt atgaccaatt gtactcaggt gacccaacct ttatcacaac
     3841 ttctatggct ggtatgggta acgacggtcg tcaccgtgtt actaagatgg actaccgttt
     3901 cttgaacact cttgacaaca tcggtaactc accagaacca aacttgacag ttctttggac
     3961 tgacaaattg ccatacaact tccgtcgcta ctgtatgcac atgagccaca aacactcttc
     4021 tatccaatac gaaggtgtaa caacaatggc taaagacgga tatggtgaaa tgagctgtat
     4081 ctcatgctgt gtgtctccac ttgatccaga aaatgaagaa caacgccaca acatccagta
     4141 cttcggtgct cgtgtaaacg ttcttaaagc ccttcttact ggtttgaatg gtggttacga
     4201 cgatgttcac aaagactaca aagtatttga tatcgaacca atccgtgacg aagttcttga
     4261 atttgaatca gttaaagcga actttgaaaa atctcttgac tggttgactg acacttacgt
     4321 agatgccttg aacatcatcc actacatgac tgataggtac aactacgaag ctgttcaaat
     4381 ggccttcttg ccaactaaac aacgtgccaa catgggattc ggtatctgtg gatttgctaa
     4441 cactgttgat acattgtcag ctatcaaata cgctacagtt aaaccaatcc gtgacgaaga
     4501 tggctacatc tacgattacg aaacaatcgg tgactaccca cgctggggtg aagatgaccc
     4561 acgttcaaac gaattggcag aatggttgat cgaagcttac acaactcgtc tacgtagcca
     4621 caaactatac aaagacgcag aagctacagt atcacttttg acaatcacat ctaacgttgc
     4681 ttactctaaa caaactggta actcaccagt tcacaaaggt gtatacctca acgaagatgg
     4741 ttctgtgaac ttgtctaaac ttgaattctt ctcaccaggt gctaacccat ctaacaaagc
     4801 taaaggtggt tggttgcaaa acttgaactc actttctagc cttgacttta gttatgcagc
     4861 tgacggtatc tcattgacta cacaagtatc acctcgcgct cttggtaaga ctcgtgatga
     4921 acaagttgat aacttggtaa caatccttga tggttacttc gaaaacggtg gacaacacgt
     4981 taacttgaac gttatggact tgaacgatgt ttacgaaaaa atcatgtcag gcgaagacgt
     5041 tatcgtacgt atctctggat actgtgtaaa cactaaatac ctcactccag aacaaaaaac
     5101 tgaattgaca caacgtgtct tccacgaagt tctttcaatg gatgacgcct tggatgcatt
     5161 gagctaatca agttcttgaa taataaaaag gaaccctcgg tcaaacgact gagggttttg
     5221 tgcttgggat agtatgagca attccttcgg cgcaatatgc aatgtttttg ggaaggaata
     5281 gtggaccgaa tctgaaatat aatagattga aactagaata gtacaccttt acttctaaaa
     5341 cattcttaga aatcgatttg actgtcctga tcgatttgtc ctattcttat ttcattttac
     5401 tatagtccgc tgaaacggct caaacagtgc tagaaattga ctggaattct ctaagtgatt
     5461 tgttccgatt ttatttcatt tcatcataaa aataagatga ctggctaatt gacaatcatc
     5521 ttgtttgata ctgttaataa aattcgcgaa gtttatcttg attttcttta aaaaattttt
     5581 ctaaccaatc cataccataa gcataactaa aaccttctaa tagaacagag aggtcaatag
     5641 tatcaaatcc catgtctttt aaatatttaa aggtatcgaa tggtgaatga aagtttttgt
     5701 atttaataat tgcaccaata tcttgcaaat cctgctctct gatactcatc atcttcattc
     5761 ctaacacata ctcaataggg actactaaaa cggtcagatt ctcaaatgag tacaaggatt
     5821 cgcataaact taagggaggt tgtttgttca tatttgcttt gcaacatgat tgttgagcca
     5881 taactcttcg tggatgttaa gattaaactg ttttcctaca cgagcaataa tttcattgat
     5941 tttctgattt tggtcataaa aagcatcaac atcttgtgtg gcacgtaaac catgatattc
     6001 taagacataa ccataattgt taaagtcaga ttttcctgaa ttaatttctt atttagggct
     6061 tggaagaccg gtttcatttt atccatgttt gtatttctcc atcaattttt gaacattggt
     6121 taacttagca ggtttattta atgaaatcac atatttatga gttggagtat gctcttgaaa
     6181 ggcatacttc aagctaattt tttgaaaacg ggttagttct ttggagtcta gcaacttttc
     6241 tacatcttgg tttgttaaat aagaatagtc ttcaaaaata acttttcgca aatagcgaaa
     6301 ccaatggctt gcgttgaatt gtgattgttt ggatgcctgt atcatataat cgtaccaatc
     6361 cattgtcttc ctcctataaa atttagttta tattattgta gtttatattc aaaaatgtag
     6421 tttttcttaa ttagctcgta tctataggat gatactgaaa atcttcttgt tgctttaaat
     6481 cacaatcgaa aaattctgtt tttcatctta gaaaagaatg tttagaaatg taaaatgaac
     6541 cttttttctt atccgaaaac cttactaaag tatataattt aggcagtcaa ttctgtatga
     6601 taatgtttgt actatcgtcg agtttttgct tgattgccta acgagataaa ttttagaaga
     6661 gttttcggtg tgatttgaca agtttctgac tggaaggata gttacactag tattgtttat
     6721 taaaatgagc agatagagaa aatttggaat ctatttgctt attatcaatc gtttttttag
     6781 cttatttgtc ttagattggt atagaactga gctatggatt aatcttcttc tatcttatcc
     6841 tgttcctaaa tatgttggta gaaaaatgaa gcagttgtta cgagtgtctg tattgggaaa
     6901 aattttgtct atagaattct ttaaatgata tgaaggctag gaatgccaaa acactgacat
     6961 atttcgttta aagtctatcc agtctcttca attgtatttg tagaaatgct atcagtaata
     7021 tattcgcgaa cactatgatt tacaacagtg tggtcgtaca tctttgtaac tttattatac
     7081 aacaaccatt tacaggtgta aagttgagca gtgtctttag taaatttagg gacttgtttt
     7141 gtcatagttt tgatacctgt attcgttgtt tcatgagcat ttgacgtttc ttttcatgta
     7201 ggcatttcaa caattagaat gatatttttc cgaggatgaa cttatatatt gtgacttttt
     7261 agagttatga tgcctcttga tttgactacc gctatcaatt tcatccactt ttacagtttc
     7321 atggttttat gaaccgaaac atctaggtac aggttttagc atcaattgat tgtttttgag
     7381 ccatatgaag ttgaaacgtg gagatgcttt tcttgtgata acgccctatt caaagaggaa
     7441 taaccgtttt tggagagagt tcagtactat gtggcgctaa atactatatg taaaacatat
     7501 attaaacaag atttaactaa ggagaattgt aaaaacaaaa atgagaattt catataaagt
     7561 ttattctagg agtatgtatc ttgaataaaa atcgttattt aagttcaggg ttatgatgaa
     7621 tgtttttata ataataaaat gcagctagaa gaaaagttat tttaatataa atcactcaac
     7681 atagagagaa ggcggtttcc tatatggaag tcgtcttgtt ttcatattgt ctaaatacga
     7741 gatatctact acaggttata gttgatttaa acaggtctat agatttctaa tatattaagg
     7801 tgaaataata tcttgtaata cattgctatg ttctatgaaa aaagcgacga tagctaatgc
     7861 acaagctcct atacttccac gatgtttgtt gtaaggtaaa atttcaattt ctatattacg
     7921 agtaaaggga acgaagtgga gctggtcttg gattttatcc ctgacttcat gagtgaaagg
     7981 ttgataatta agcaattgac tgttgatata gattttatca gcaggattga tgaggaggag
     8041 atttgcaata gaagtggcta ataaattgac tcctttatca atttgttgac gtaaagcgga
     8101 gtcgcctaaa ttataagccg ttaaaagggt gtctaaatga atgtcttttt cagtctttac
     8161 aaggcttttt agtacagtta gttgggaatt tttaaataat aattgggcgt gtttgattaa
     8221 ccaagcatcc gaaatatatg tttgtaaaca accttttttt ccgcattcac aatattgccc
     8281 attcaattcg acaatggtgt gtccaatttc tccgatataa ggatttttag aggctcctat
     8341 tttttctttt gtgaaaaagg aagtgtaaat acctaatcca gcgtgtagga aaataaagtt
     8401 atcgggggta ttgtgtggat taaaaaggta ttgtcctata gccatacaat cgatattatt
     8461 ttttacaata aaaggaaaat tgaatctttt aattacattt aataaattaa aagattccca
     8521 tatggggttg tttgtaatga tacttccgga gtctttgtta taatgtccag gtattgataa
     8581 gccaaatcca agtaattttg tttccaaagg gacgtactct atagctgttt ttatcatatt
     8641 ggtaatggtg gaattgattt ctgaaatagg ataatcttca ttcaaaattt ctgtctcgaa
     8701 aagagttttc ccttgtaagt cacatagact gagaaagata cctaggacgt ttatttcaat
     8761 acctccaaca acatacggaa tattatctgt gatagaaata gtttttctac gtcttccaga
     8821 tccggaaaac tcgctaaatt catcaccagt ttcgtatatg agggactgtt cgcttagctc
     8881 ttttatgatg ttagtcgttg ttgctggagt aagtcctgtt tcattaacaa tatctgtacg
     8941 ggatgttgct ggatttcgat atagaaactc cagtatagtg gctctatttt gtaaaaaggc
     9001 tgattgtttt gtaatcattt gtttcctcct ttggtttatt ttatattaaa cataagaaaa
     9061 aatcaattaa aattattatt ttatacaaag aaaaaaatat tgtaaaaaca acaaaaaata
     9121 tattgacaac gctttctgtt agtggtatat ttaatttata aaaaataaaa aaaggagttc
     9181 cggtgatgaa caatatttta gcgtttttag aaacaaaagt cgctccgttt ggtgaaaaag
     9241 ttggcaacca acggcatttg aaagctattc gtgaaggatt tatgatggca atgcctttga
     9301 ttttagtcgg atctttattt cttattctaa tcagttggcc tcaagaggat tttacaaatt
     9361 ggctgaatag tgttggattg ctaagtatct tgacaactat gaatcagtca acagtagcga
     9421 ttatctcctt ggtcgcttgt ttcggtattg cctacaggtt gtcggaagga tatggtacag
     9481 atggtccgtc ggcagggatc atagccttat ccagttttgt attgatggca cctcgttttt
     9541 cgagtatggt ttatgataaa aatggggagc aggtcaagca gttatttggc ggcgcaatac
     9601 cattttctag cctgaatgca tcttctttgt ttatggcgat tactattgga ttggttacag
     9661 cagagattta tcgtatgttt atccagcgcg gaattacgat aaaaatgcca agtggtgtcc
     9721 cagatgtggt aagtaaatca ttttcagctc ttttacctgg ctttactact tttgttttgt
     9781 gggctctggt cttaaaaggt cttgaagcgg caggagttgc aggaggtctc aacggactcc
     9841 taggtgcaat tgttggaaca ccgcttaagt taattgcagg aacgcttcca ggtatgattc
     9901 tatgtgttat tgtaaactca ttcttttggt tctgtggagt taatggggga caagttttaa
     9961 atgcttttgt agatccagtt tggttacaat ttactacaga aaaccaagaa gctgtggctg
    10021 caggacaaac actccaacac attattacat taccgtttaa agatttattt gtatttattg
    10081 gtggcggtgg agcgactatt ggtcttgcga tttgtctctt cctatttagt aagagtcgtg
    10141 cgaataaaac attaggtaag ctagctatta taccgtctat ttttaatatc aatacagcta
    10201 ttctatttac gtttccaaca gttttaaatc cgattatgct gattccgttt attgctactc
    10261 ctacaatcaa tgccttaatt acctatgtat caatggctgt aggattagta ccctacacaa
    10321 caggtgtaat ccttccgtgg acaatgccac cgatcatagg aggcttcctt gcgacaggag
    10381 ctagttggcg aggagctcta ttacaagttg ttttgatttt ggtttctgta gcaatttatt
    10441 atccattctt caaaattgca gataaacgca atcttgaaaa agaaaaagct actgttggag
    10501 ggaaataaga tggttatcag agtatttgat cagcagaaaa atacttattc tagctttgcc
    10561 ttagaggaat taagttacta tataaatcgg gtctttaaga ctgacataga acttgtcgag
    10621 gagaaggaag cggatatttt tgtaggatta gtcaataaag aggatagaaa agaccatgtt
    10681 cttatctcat tagacaaggg taaggggaga attgagtcta atacaattgt aggtttgctt
    10741 attggaattt accgaatgtt tcatgaattt ggggttgtgt atactagacc agggcgcgga
    10801 catgactttg ttccagagtt acgatttgaa gattttttag ataaagagct atctatagat
    10861 gaaacagcca gttactatca taggggagta tgtatagagg gagcagattc atttgaaaat
    10921 atactagatt tcattgattg gctacctaag attgggatga acagtttttt cattcagttt
    10981 gaaaatccct attctttttt gaaacgttgg tatgaacatg agtttaatcc atacctaaat
    11041 aaagaaaaat tctcaaatga attagtacaa gaattgagtg ataggttgga taaagaattg
    11101 caaaaaagag gtcttattca tcatcgtgtt ggtcatggat ggacaggtga ggttttaggt
    11161 tactcttcaa aatttggctg ggaatcaggt cttagtattt cagaggagaa gaaaccctat
    11221 gtcgctgaaa taaacgggaa acgagaatta tttaatacgg ctccgatttt aaccagtctg
    11281 gatttttcaa atccagatgt ggcggataag atggtagaaa ttatcaagga ttatgccaag
    11341 aaaagacctg atgttaacta cttacatgta tggttgtcgg atgctcgtaa taatatttgt
    11401 gaatgcgaaa actgtagaca agaattggtt tcggatcagt atattcgtat tctcaatcaa
    11461 ttggataggg ctttaacgag tgagggatta gatacaaaga tttgttttct gctttaccat
    11521 gagttgttat gggcgcctca gaaagaaaaa ttagataatc ctgaacgctt taccatgatg
    11581 tttgcaccga ttacaagaac atttgaaatg agttatgcag atgtagattt tgacaattcc
    11641 atacctacgc ctaaacctta tctgcgtaat aaaattatac ttccgaattc tcttgaggaa
    11701 aatttatctt atctttttga gtggcaaaaa acatttaaag gagatagttt cgtatatgac
    11761 tatcctttag ggcgtgctca ttatggcgat ttaggctata tgaaaattag tcaaaccatt
    11821 tacagagatg tatcttatct ttctaaccta catttgaacg gttacatttc gtgtcaagaa
    11881 ttacgtgccg gattccctca taattttcct aattatgtta tgggggaaat gctctggaag
    11941 aagacaagaa gttatgaaga attgattgaa gaatactttt ctgctttgta tgggtcaaat
    12001 tggcagtctg ttgttgaata tttagaaaaa ttatccagtt attcctcatg tgattatttt
    12061 aatgcaattg gcagtcgtca aaatgatgtt ttagcgaatc attattatat agcttacaat
    12121 ctagctgata attttttgcc aattattgag gaaaatattt ctaagttatt aaatagtcaa
    12181 aaggatgaat ggaaacagct cagttatcat cgtgaatatg ttgttaagat ggcgaaggct
    12241 ttatatcttc aagcaaccgg aaaaacaagg caagctcaag atgaatggag aaatgtgttg
    12301 aattatatcc gtgggcacga attgctattt caatctaatt tggatgttta tcgtgtaatt
    12361 gaagtagcaa aaaattacgc tggtttccac ttataaatca taagtataga aaatgaacca
    12421 aggtattcag agaagattga tcctaaatat tatgaaattt aaggattttt aagatattta
    12481 gggtcgactt tctatttata tcgtagcgaa gtcattttaa taatgatgtg taaaagatgg
    12541 atcaagattg aggaggaaga aagatgaaat caaaagaaga aataaatatg cttggtttta
    12601 caattgtcgc ttacgcagga gatgcaaggt cagatttgat ggatgctttg gcgtttgcga
    12661 gagatggata ttttgaacag gcaagagaat tggttgagtc tgcaaacgac tcaatagtgt
    12721 ctgcccatcg agaacagact aatttattag cggaggaggc atctggagat aattttgaag
    12781 tgagttttat catgattcat ggtcaagata ccttgatgac aacgatgcta ttgtatgatc
    12841 aggtcaagtt ttttattgat gaatatgaac gaattcgaaa gattgaagaa catattggtt
    12901 tgcaatgagg attagtcatg gaaaatttac aggttaaagc cttaccgaag gagtttttat
    12961 taggagctgc taccgctgct tatcaagtag agggtgcaac tagggtagat ggcaaaggaa
    13021 caaatatgtg ggatgtttat ttgcaagaaa acagtccgtt cttaccagat ccagctagtg
    13081 atttttatta tcgttacgaa gaggatataa ctttggcggc agaacatggt ttgcaggctt
    13141 tgcgtttatc tatttcttgg gttcgtatat ttcctgatat agatggggag cctaatatat
    13201 tagctgttcg ttattaccat agagtctttc agtcttgctt aaaacataat gtgattccgt
    13261 ttgtttcttt acatcatttt gattcgcctc agaaaatgtt agaaacaggg gattggttga
    13321 atagagagaa tattgatcgt ttcatacgat atgctcgctt ttgtttccaa gaatttacag
    13381 aagtcaagca ttggtttaca atcaatgaac tgatgtctct tgctgcaggt caatatatag
    13441 gaggtcagtt tcctccaaat catcattttc aattatctga agcaattcaa gcgaatcata
    13501 atatgttgtt ggcgcatgct cttgcagtcc tcgaatttca tcaattagga attgagggag
    13561 agataggttg tattcatgct ttaaagccag gctatcctat tgatgggcaa aaagaaaata
    13621 ttttggcagc taaacggtat gatgtttata ataataaatt tctattagat ggaacttttt
    13681 tgggctacta cagtgaggac acgctttttc acttgaatca aatattggaa gctaataatt
    13741 ctagctttat tattgaagat ggtgatttag aaattatgaa gagagctgca gctcttaata
    13801 cgatgtttgg gatgaattat tatcgttcag aatttattcg tgaatacaaa ggtgaaaata
    13861 gacaagaatt taattcaaca ggaataaaag gacagtcttc ttttaaatta aatgctctag
    13921 gtgaatttgt aaaaaaacct ggtattccga caacagattg ggattggaat atttatcctc
    13981 aagggttatt tgatatgttg cttcgtatca aagaagaata tcctcaacat ccggtcattt
    14041 atttaactga aaatggtaca gcccttaaag aagttaagcc agagggcgag aatgatatta
    14101 ttgatgacag taagagaatc cgttatattg agcaacattt acacaaagtt ttagaggctc
    14161 gagatagagg agtcaatatt caaggctatt ttatatggtc tttgcaagat caattttctt
    14221 gggcgaatgg ctacaataag cgatatggtc ttttctttgt tgattatgaa acacagaaga
    14281 gatatattaa gaaaagtgct ctttgggtaa aagggctaaa acggaattaa ggttagcgat
    14341 ttgactgatg tttaatatat tttaactatg agcttaaatt ttttacagga ggagttttta
    14401 tggataagtt agtcgctgcc attgaaaagc aacaagggaa atttgaaaaa atttctacta
    14461 ataattatat gatagctatt aaagatggat ttattgctac tatgccttta attatgtttt
    14521 caagcttttt gatgattatt attatgattc ctaaaaattt cggagtagag ttaccgagtc
    14581 cagctattgc ctggatgagg aaagtgtata tgctaaccat gggagttttg ggtattattg
    14641 tttcagggac agttgcaaag tcattggctg gaaatgttaa tagaaaaatg cctcctggaa
    14701 aggtaataaa tgatacttct gcaatgttgg cggccatatg tggctatctt gtattaactg
    14761 taacgcttgt agttgatgag aaaacgggat ctacaagttt gtcgacaaac tatttaggat
    14821 ctcaaggatt gataacttcg tttgtcagtg cctttattac tgtaaatgtt taccgattct
    14881 gtattaagcg agacattact attcatttac ctaaggaagt tcctggggct atatcacaag
    14941 cttttagaga tatttttcct ttttcttttg ttttacttat tagtggtttg ttagatattg
    15001 tatctcggtt tagtttagat gttccttttg cccaagtatt tcaacaacta ttgactccta
    15061 tttttaaggg ggcagaatca tatcctgcta tgatgttgat ttggtttatg tgtgctttgc
    15121 tttggtttgt tggaattcat ggaccatcta ttgtcttacc tgctgttaca gctttacaac
    15181 tgagcaatat ggaagagaat gctcaacttc ttgcaaatgg gcagttccct tatcattctt
    15241 taacacctaa tttcgggaat tatatcgctg ctattggagg aacgggggct acctttgttg
    15301 taccatttat tttgattttc tttatgcggt ctaaacaatt aaaatcggta ggtaaagcta
    15361 caattactcc tgttttattt gcggtaaatg aacctcttct atttggtatg cctgttattt
    15421 tgaatcccta tctttttgtc ccttttttga tgactccacc agtgaatgta tttctaggaa
    15481 aggtatttat tgatttcttt ggaatgaatg gattttatat ccagttacct tgggcctttc
    15541 ctggtccctt gggattgtta attggaacga attttcaact tatctccttt gtatttttat
    15601 ctttgatgtt agttgtcgac atattgattt atttgccatt ctgtagagcg tatgatagac
    15661 agttactggt gaaagaagat attgcaagct caaatgatat tattttagag gaggatacaa
    15721 gtgaaataat gcctggtgag atagatgtaa taaaaagtaa ggagttgaaa gtactggttc
    15781 tttgtgcagg gtctggaaca agtgcgcaat tagccaatgc aattaacgag ggcgctcaat
    15841 tagcagaagt tagagtgatt gcgaattcag gagcgtacgg agctcattat gatattatgg
    15901 gtgtttatga tttaattatt ctggccccac aagttcggag ttattataga gagatgaagg
    15961 tggatgcaga aagattagat attcagatag ttgctaccag aggaatggaa tatattcatt
    16021 taacaaagag tccaagtaaa gccttacaat ttgtattgga gcattaccaa gctgtgtagt
    16081 aagtttttcc atcttttatt tgagtaaaga ttttgcttac agataggctt ggatttaaaa
    16141 acgttccccc ttttttaata taagaatccc tctttcacaa ttgtaaaaag agggattttg
    16201 tattttatct cttagaccaa gttctcttca taaagagaag gaggattggg taaatctcca
    16261 agcgccctgc aatcattgca aaggatagga gaatttttga gatgggacta aagattgaga
    16321 aactagaagt ggttcctaga ataggcccga tattattgaa acagctaaag acagcgctgg
    16381 tcacgaccag aaaatcattg ctatctaggc tgacaataaa gataagcgct agcaaaatca
    16441 tagcatagat gacaaagtac ttgagaatct tatgctgggt atctttgtca atcaccgttt
    16501 tattaacatg gagggtcaaa acacggtggg gcgataggat tgacaaaatt tggtttttgg
    16561 caatttttga aaggatgagg cctcgaataa tcttgagtcc acctgcagtt gatccagcag
    16621 agccaccgat tgccatgagg aaaaggagga taaactggga gaagaggggc cagttggtaa
    16681 tatctccata tccaaaacca gttgttgtaa tgatgttgga aacctggaag aaggtcattt
    16741 caaagctctt tgaaaaccct gggtagaggt agagggtgtt gaggctaatc aagcctgtag
    16801 aaaccagtac aatgaccaag taagccctaa gctcttcatc tccaaagaag gccttgatgc
    16861 gacggagcat gaggtagtag tagaggttga aatttactcc aaaaaccaga actccgatac
    16921 tgaccagata ggtaatcagt gagctgccat agtgggcaat tccgtcgtta tagacggtaa
    16981 agcctccagt tcccgctgtc cccatagcaa tgacaaaact atcgtagaga ggcataccag
    17041 ctagataata gatgatgaca aagagggaga agagagctag ataaaggaga tagagaatct
    17101 gggcagtgtt ttttagtttg gatacaacct tgccaaaaac aggacctgga acctcagcct
    17161 tcatcacctc taggtggcta tttttggcat tgtccataat agcaagtgca aaaacaagca
    17221 ctcccatccc tccaatcaag tgggtaaaac ttcgccagaa gaggagggaa cgactgagaa
    17281 ctgaaacgtc gttcaaaata cttgctccag tagtcgtaaa gccggaacta atctcaaaaa
    17341 aggcatcaat aaggctgggg atttgcccag aaaagacaaa ggggagacca ccaaagaaag
    17401 accaaaggat ccaacagagg gcaacgatca agactccctc cttggcataa atccgttgat
    17461 tttttggctt ctgtaaactc cctgaaccgc ctaacaatac gagaatccct atggtcgaaa
    17521 agagggctgt aaagacttgg ctcgattcac ggtaatagac agcgatagcc acaggaacca
    17581 agaggagaac agcttcaatc aaaagtaact ttgaaaggag gtaacgaatc atacttttat
    17641 tcatttctta cctcgcaatc aagtcataaa tcttggtgat gtttggcaac aaggttgtta
    17701 ctaggagctt gtctccaact tccaacatat cctccccagt tgggaaaata gtcttgccct
    17761 ttcgaataat ggctgcaata agaacccctt ttttcaattt cagttgagaa agaggtttgg
    17821 cagtcatttt attggcttcc ttgatatgga attgcagggt ttcgatttgg ccattggcta
    17881 gatggtgcat ggcttgaagg tctgaatact gggcattaac tcgaccacga ataaagtgca
    17941 taatcgtatc tacagcgatg cttttaggtg tgatgatact tgaaaaatca ggcgcattga
    18001 taatctcgag gagactggta cgattgacct tagtaatatt tttctgtaca cctaccctgt
    18061 caaggaacat agatgtaatc agattttcct catcgactcc tgttagagtc gcaacggcat
    18121 catagtgttg agcactttct tccagcagga tatcttttgc ggttccatct ccttgaacga
    18181 tgtagagatt tgggaatttc tcgctaaaga agctggcgat ttcaggattg atttcaatga
    18241 cttttgtatc gatacgacta tctttgagaa taccaagtag ataataggca attctacctg
    18301 ccccaacgat gagaaggctc ttcacggcgc gtgatttaaa ataattatgg aagagtatca
    18361 tatcgacacg gttaccagtg acaaagattc tatctttatc ctgtacagtc atgtcaccgc
    18421 ttggaatgat aatttgatga tccctctcta tcgcacagac aatgacatta ccaaattttt
    18481 tacgaaaatc agaaatgggc atttggcaaa gaccgctggt ggacttgacg acaaattcca
    18541 tgaggctaac gcgtccacca gcaaagcgtt cgacagacag ggcgttgggg aagtcaatga
    18601 tattcgcgat agcacgggca gccaagagct caggattaac gataagagaa aaaccgagaa
    18661 tattcttttc cttgaaataa gagttagaat attcagggtt ccgcacccga acgatagttt
    18721 ctttagctcc cattttcttg gctagaactg ctgcaatcat gttgacttca tcgtgctcag
    18781 tcagggcgat aaagatatca caatcttgga cgctggcttg ctcaagaatg gcaaaatcgg
    18841 ccccgttacc aaggatacca atgatatcaa agcgactgac aatatgattg agaacagctt
    18901 cgtcttgctc aatcagcaaa acatcatgct tttctgcaac caaggagcga cagagggcaa
    18961 aaccaacttt tccccctccg acaaggataa ttttcataat aaaacctact ttttcatgat
    19021 gtaactatca tacccttttt caagaaaaaa tgcacctact agctaataac aagagctttt
    19081 agtgaaaatt cgctataaga taaaactata ccctaaccaa ttgaaatagc tattagcgac
    19141 tttctctgaa atatggtatg ataaaggata tacaaggaga taaaatgaat aataatttac
    19201 tggtattaca atcagacttt ggtctggttg atggtgcggt atcggctatg attggagtgg
    19261 ctttagaaga gtctccaacc ttaaaaatcc atcacttgac gcacgatatc acgccttata
    19321 atatttttga ggggagctat cgtctctttc agacggtgga ttactggcct gagggaacga
    19381 cgtttgtatc ggttgtcgat ccaggtgtcg gttcgaaacg taagagtgta gttgccaaga
    19441 ctgcaaaaaa tcaatacatt gtcacgccag ataatgggac gctttccttt atcaagaaac
    19501 acgttggcat tgtagccatt cgtgagattt ctgaggtggc caataggcgt caaaacacag
    19561 agcattctta taccttccac ggtcgtgatg tctatgccta tactggtgct aaactggcca
    19621 gtggtcacat tacttttgag gaagtagggc cagagctcag tgtggaacag attgtagagc
    19681 ttccagtcgt agcgaccatc atagaagatc atctggtgaa gggagccatt gatattctgg
    19741 atgtgcgttt cggttcgctt tggacctcta tcacacggga agaattttac aagttggaac
    19801 cagaatttgg tgatcgtttt gaagtgacca tctatcatgc tgatatgctg gtctatcaaa
    19861 atcaggttgt ctatggcaaa tcatttgcag atgtgagaat tgggcaaccc atcctttaca
    19921 tcaactctct ctatcgttta ggtttggcta tcaaccaagg ttcctttgcc aaggcctata
    19981 atgtaggtgt cggttcatct tggaccattg aaataaagaa aatagaagga taaaatagga
    20041 gaatagtatg gaaatcaaat ttacaattaa acaagttgtt gctgtcggaa ttggcgctgc
    20101 cctctttgtc gtcatcggga tgatcaacat tccaacccct gttccaaata caagcatcca
    20161 gcttcagtat gcggtacaag cgctactttc tattattttt ggaccgatta tcggtttgct
    20221 tgttgggttg attggtcatg caatcaagga ctctcttgtt ggttatggtc tatggtggac
    20281 ttggattatc gctagcggac tctttggttt agttgtggga ctttttagaa agtacgttcg
    20341 cgtgatcaat ggtgtttttg actggaaaga tattcttatt tttaacctca ttcaactact
    20401 tgcaaatgcc cttgtttggg gtgtcttggc accacttgga gatgttgtga tttatcaaga
    20461 agcggcagaa aaagtatttg cacaaggaat tgttgcggga attgccaatg gtgtatctgt
    20521 agctattgca ggaactcttc tcttacttgc ctatgcagga acccaaactc gtgcaggaag
    20581 tttgaaaaag gactaatact caatgaaaat caaagagcaa actaggaagt tagccgcagg
    20641 ttgctcaaaa cagtgttttg aaattgtgga ta
//
LOCUS       DAVBBO010000041        20624 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ST1
            SAMEA2066453-rid20184263.denovo.041, whole genome shotgun sequence.
ACCESSION   DAVBBO010000041 DAVBBO010000000
VERSION     DAVBBO010000041.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2066453
            Sequence Read Archive: ERR351777
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 20624)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 20624)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980402.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980402.1
            Genome Coverage       :: 176x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:17:33
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,141
            CDSs (total)                      :: 2,104
            Genes (coding)                    :: 1,953
            CDSs (with protein)               :: 1,953
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 16S)
            partial rRNAs                     :: 1 (23S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 151
            CDSs (without protein)            :: 151
            Pseudo Genes (ambiguous residues) :: 0 of 151
            Pseudo Genes (frameshifted)       :: 73 of 151
            Pseudo Genes (incomplete)         :: 76 of 151
            Pseudo Genes (internal stop)      :: 40 of 151
            Pseudo Genes (multiple problems)  :: 32 of 151
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..20624
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2066453-rid20184263.denovo.041"
                     /strain="ST1"
                     /db_xref="taxon:1313"
     gene            complement(<1..299)
                     /locus_tag="VQU30_001462"
     CDS             complement(<1..299)
                     /locus_tag="VQU30_001462"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001829151.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="argininosuccinate lyase"
                     /protein_id="HET2447554.1"
                     /translation="MMYLDGGGVGCNWWNKRDNIAAAAVSGGMSVYQTYAIKKLIANR
                     GMMSRVVRSAITRYIGGVSMATITNALNIAATVAEVFSLGGAIAYGLDIVDGKFDG"
     gene            complement(279..347)
                     /locus_tag="VQU30_001463"
                     /pseudo
     CDS             complement(279..347)
                     /locus_tag="VQU30_001463"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000424474.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="argininosuccinate lyase"
     gene            complement(762..974)
                     /locus_tag="VQU30_001464"
     CDS             complement(762..974)
                     /locus_tag="VQU30_001464"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000989850.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2447555.1"
                     /translation="MMVVLISVIVAFLYHKITEYVNNRKIDIVIFLSLLISHFIWNYY
                     FLPIEILIAISGANLLLSFLKKLQIK"
     gene            complement(993..1352)
                     /locus_tag="VQU30_001465"
     CDS             complement(993..1352)
                     /locus_tag="VQU30_001465"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000424431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2447556.1"
                     /translation="MELVLPNNYVVIDEEEMMYLDGGAIYIPRWAITGAITGAAYAAL
                     AAAGGGGLQLVLASYGLRSALVAGIVKGLGVLGIHIGNAFANTVIRSIASAGIGAGAD
                     WILPILLMAGMGDVIIN"
     gene            complement(1330..1668)
                     /locus_tag="VQU30_001466"
     CDS             complement(1330..1668)
                     /locus_tag="VQU30_001466"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000915343.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase C39"
                     /protein_id="HET2447557.1"
                     /translation="MLKKYPCTMQHDQSDCAAAVVSTVLLSYKKELSIMKIREIIGTD
                     MYGTTVSGIVSGLNKLNFTVKAVRVALEDLTPKLTFPAILQVKNDLGQNHFVVLHSIK
                     EKINGTRITK"
     gene            2134..2997
                     /locus_tag="VQU30_001467"
     CDS             2134..2997
                     /locus_tag="VQU30_001467"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001268160.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HET2447558.1"
                     /translation="MRYDFGKVYKEIRESKGLTQEEVCGGVLSRTSLSKIESGKTTPK
                     YENMEFLLRQINMSFEEFEYICQLYQPSQRTEIMQTYLNMRSIIGTSDLVNLFQKCQD
                     YLKTHHDLPIEEIRDMLEVVIYLRQHGAGELSKHAEQVVKKLWKKIEKQDTWYESDLK
                     ILNTILFSFPIEYLHLITGKILQRLEVYKNYQHLYDLRMTILLNLSTLYLYNQDKNMC
                     KQICYTLLEDAKNKKSYDRLAICYVRIGICTDDSKLIQKGFSLLELTEETSMLSHLKK
                     EVEIYYQAKER"
     gene            complement(3049..3621)
                     /locus_tag="VQU30_001468"
     CDS             complement(3049..3621)
                     /locus_tag="VQU30_001468"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000843467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="HET2447559.1"
                     /translation="MKSITKKIKATLAGVAALFAVFSPSFVSAQESSTYTVKEGDTLS
                     EIAETHNTTVEKLAENNHIDNIHLIYVDQELVIDGPVAPVATPAPATYAAPAAQDETV
                     SAPVVSETVVSTVSGSEAEAKEWIAQKESGGSYTATNGRYIGRYQLTDSYLNGDYSAE
                     NQERVADAYVAGRYGSWTAAKNFWLNNGWY"
     gene            3863..4534
                     /gene="sdaAB"
                     /locus_tag="VQU30_001469"
     CDS             3863..4534
                     /gene="sdaAB"
                     /locus_tag="VQU30_001469"
                     /EC_number="4.3.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015606087.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-serine ammonia-lyase, iron-sulfur-dependent
                     subunit beta"
                     /protein_id="HET2447560.1"
                     /translation="MKSLRFQSVFDIIGPVMIGPSSSHTAGAVRIGKIVSSIFDDTPT
                     EVEFQLFNSFAKTYRGHGTDLALVAGILGMDTDDPEIPNSLEIAHKRGIKIVWTIQKD
                     SNAPHPNTTKITVKNAHKTISVTGISIGGGNIQVTELNGFAVSLNMNTPTIIIVHQDI
                     PGMIALVTEALSRYGINIAQMNVTREKAGEKAIMIIEVDSRNCDEAIEEIRKIPHLHN
                     VNFFK"
     gene            4543..5415
                     /gene="sdaAA"
                     /locus_tag="VQU30_001470"
     CDS             4543..5415
                     /gene="sdaAA"
                     /locus_tag="VQU30_001470"
                     /EC_number="4.3.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000500050.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-serine ammonia-lyase, iron-sulfur-dependent,
                     subunit alpha"
                     /protein_id="HET2447561.1"
                     /translation="MFYSIKELVEQADLDFQGNVAELMITTEFELTGREREEVFLLME
                     RNLEVMKASVQLGLNENKSRSGLTGGDAAKLDHYIKNEKTLSDYTILSAARNAIAVNE
                     HNAKMGLVCATPTAGSAGCLPSVLTAAIEKLDLSHEQQLDFLFAAGAFGLVIANNASI
                     SGAEGGCQAEVGSASAMSAAALTLAAGGTPYQASQAIAFVIKNMLGLICDPVAGLVEV
                     PCVKRNAMGASFAFIAADMALAGIESKIPVDEVIDAMYQVGASMPTAFRETAEGGLAT
                     TPTGRRLQKEIFGE"
     gene            5437..6069
                     /locus_tag="VQU30_001471"
     CDS             5437..6069
                     /locus_tag="VQU30_001471"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000200889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HET2447562.1"
                     /translation="MTSITAIFFDLDGTLVDSSIGIHNAFTYTFKELGVPSPDAKTIR
                     GFMGPPLESSFATCLSKDQISEAMQIYRSYYKAKGIYEAQLFPQIIDLLEELSSSYPL
                     YITTTKNTSTAQDMAKNLEIHHFFDGIYGSSPEAPHKADVIHQALQTHQLAPEQAIII
                     GDTKFDMLGARETGIQKLAVTWGFGEQADLLNYQPDYIAHKPLEVLAYFQ"
     gene            6095..6193
                     /locus_tag="VQU30_001472"
                     /pseudo
     CDS             6095..6193
                     /locus_tag="VQU30_001472"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820552.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus and C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopyranose mutase"
     gene            complement(6417..8267)
                     /locus_tag="VQU30_001473"
     CDS             complement(6417..8267)
                     /locus_tag="VQU30_001473"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001035735.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide biosynthesis protein"
                     /protein_id="HET2447563.1"
                     /translation="MNKKLTDYVIDLVEILNKQQKQVFWGIFDIFSMVVSIIVSYILF
                     YGLINPAPVDYIIYTSLAFLFYQLMVDFWGLSASISRYSKITDFMKIFFGVTASSVLS
                     YSICYAFLPLFSIRFIILFILLSTFLILLPRITWQLIYSRRKKGSGDGEHRRTFLIGA
                     GDGGALFMDSYQHPTSELELVGILDKDSKKKGQKLGGIPVLGSYDNLPELAKRHQIER
                     VIVAIPSLDPSEYERILQMCNKLGVKCYKMPKVETVVQGLHQAGTGFQKIDITDLLGR
                     QEIRLDESRLGAELTGKTILVTGAGGSIGSEICRQVSRFNPERIVLLGHGENSIYLVY
                     HELIRKFQGIDYVPVIADIQDYDRLLQVFEQYKPAIVYHAAAHKHVPMMERNPKEAFK
                     NNIRGTYNVARAVDEAKVPKMVMISTDKAVNPPNVMGATKRVAELIVTGFNQRSQSTY
                     CAVRFGNVLGSRGSVIPVFERQIAEGGPVTVTDFRMTRYFMTIPEASRLVIHAGAYAK
                     DGEVFILDMGKPVKIYDLAKKMVLLSGHTESEIPIVEVGIRPGEKLYEELLVSTELVD
                     NQVMDKIFVGKVNVMPLESINQKIGEFRTLSGDELKQAIIAFANQTTHIE"
     gene            complement(8335..9474)
                     /locus_tag="VQU30_001474"
     CDS             complement(8335..9474)
                     /locus_tag="VQU30_001474"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000096190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HET2447564.1"
                     /translation="MSSKVSGFQDKNGKVLKIMIEWWKGKFRRVVVTQNVESLLVSIV
                     ISAYNEEKYLPGLIEDLKNQTYPKENIEILFINAMSTDGTTAIIQQFIKEDAEFNSIR
                     LYNNPKKNQASGFNLGVKHSVGGLILKIDAHSKVTESFVMNNVAVIQQGEFVCGGPRP
                     TIVKGKGKWAETLHLVEENMFGSSIANYRNSSEDRYVSSIFHGMYKREVFQKVGLVNE
                     QLGRTEDNDIHYRIREHGYKIRYSPSILSYQYIRPTFKKMLHQKYSNGLWIGLTSHVQ
                     FKCLSLFHYVPCLFVLSLVFSLALLPITFVFITLLLGAYFLLLSLLSLLTLLTLLKHK
                     NGFLIVMPFLLFSIHFAYGLGTIVGLIRGFKWKKEYKGTVIYLEK"
     gene            9532..10698
                     /locus_tag="VQU30_001475"
     CDS             9532..10698
                     /locus_tag="VQU30_001475"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004254936.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CynX/NimT family MFS transporter"
                     /protein_id="HET2447565.1"
                     /translation="MKKQSLFFVPGIILIGVSLRTPFTVLPIILGNISQGLEVEVSSL
                     GVLTSLPLLMFTLFSPFSTRLAQKIGLEHLFTYSLFFLTIGSLIRLINLPLLYLGTLM
                     VGASVAVINVLLPSLIQANQPKKIGFLTTLYVTSMGIATALASYLAVPITQASSWKGL
                     ILLLTLLCLATFLVWLPNHRYNHRLAPQTKQKSQIKVMRNKQVWAIIIFSGFQSLIFY
                     TAMTWLPTMSIHAGLSSHEAGLLTSILSLISIPFSMTIPSLTTSLSTRNRQLMLTLVS
                     LAGVVGISMLFFPINNFIYWLAIHLLIGTATSALFPYLMVNFSLKTSAPEKTAQLSGL
                     SQTGGYILAAFGPTLFGYSFDLFHSWVPAVAALLLIDILMTVALFTVDRADKIL"
     gene            10837..11163
                     /locus_tag="VQU30_001476"
     CDS             10837..11163
                     /locus_tag="VQU30_001476"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000273865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="HET2447566.1"
                     /translation="MYFPTSSALIEFLILAVLEQGDSYGYEISQTIKLIANIKESTLY
                     PILKKLEGNSFLTTYSREFQGRMRKYYSLTNGGIEQLLTLKDEWTLYTDTINGIIEGS
                     IRHDKN"
     gene            11150..11743
                     /locus_tag="VQU30_001477"
     CDS             11150..11743
                     /locus_tag="VQU30_001477"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000198695.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1700 domain-containing protein"
                     /protein_id="HET2447567.1"
                     /translation="MTRTEYLTQLELYLKKLPEADRIEAMDYFRELFDDAGVEGEEEL
                     IASLGTPKEVAHEVLSNLLDKKINEAPAQKNNRQILHIALLALLAAPIGIPLGIAILV
                     TLFAILVAALTVILAFFAVSILGIIGGFLFLVESFTVLAQAKSAFILIFGSGLLAIGA
                     SSLVLLGISYVARFFGLLIVRLVQFVLKKGKRGNQHA"
     gene            11736..12647
                     /locus_tag="VQU30_001478"
     CDS             11736..12647
                     /locus_tag="VQU30_001478"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001233690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4097 domain-containing protein"
                     /protein_id="HET2447568.1"
                     /translation="MRKWTKGFLIFGVVTTVIGFILLFVGIQSDGIKSLLSMSKEPVY
                     DSRTEKLTFGKEVENLEITLHQHTLTITDSFDDQIHISYHPSLSAHHDLITNQNDRTL
                     SLTDKKLSETPFLSSGIGGILHIASSYSSRFEEVILRLPKGRTLKGINISANRGQTTI
                     INASLENATLNTNSYILRIEGSRIKNSKLTTPNIVNIFDTVLTDSQLESTENHFHAEN
                     IQVHGKVELTAKDYLRIILDQKESQRINWDISSNYGSIFQFTREKPESRGTELSNPYK
                     TEKTDVKDQLIARSDDNIDLISTPSRR"
     gene            12710..13774
                     /locus_tag="VQU30_001479"
     CDS             12710..13774
                     /locus_tag="VQU30_001479"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000808437.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2447569.1"
                     /translation="MKQEWFESNDFVKTTSKNKPEEQAQEVADKAEETIADLDTPIGK
                     NTQVEEEVSQAEVELESQQEEKIETPEGGEARTEIEEKKASNSTEEEPDLSKETEKVT
                     IAEESQEALPQQKATTKEPLLISKSLESPYIPDQAPKSRDKWKEQVLDFWSWLVEAIK
                     SPTSKLETSITHSYTAFLLLILFSASSFFFSIYHIKHAYYGHIASINSRFPEQLAPLT
                     LFSIISILVATTLFFFSFLLGSFVVRRFIHQEKDWTLDKVLQQYSQLLAIPIFLTAIA
                     SFFAFFDSLRFTALLCVISIGIILLASLHIITRPSQASETDSFYQLFLSVLVNGVIIL
                     LFFVAEVALIGDYLRILAFL"
     gene            complement(13846..14706)
                     /locus_tag="VQU30_001480"
     CDS             complement(13846..14706)
                     /locus_tag="VQU30_001480"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001140341.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4299 domain-containing protein"
                     /protein_id="HET2447570.1"
                     /translation="MAKTFFIPNKQSILGEQEILNAKSILALLDGLESHIYDVVYLRQ
                     PLNRLEYIECAIVGQSQFLFKVSYADGQKAYRVDLPDLLTETDWQIIKSFLDALLAYT
                     GTDIEGLDGFDFEAYFQASIQAYLADPVARFTICQGIFNPIFFSRENLKSFLEADGLA
                     QFEARVRAVQETDAYFARVSFYQDGEGKVHGVYHLAQGVKTVLPREPFVPAAYIEQLV
                     DKEVQWEIDLVQITGDGSKPEDYEAIARLDYAKFLEVLPPSFYHQLDANQIEVQPILD
                     KDFKTLAQEK"
     gene            complement(14828..15814)
                     /locus_tag="VQU30_001481"
     CDS             complement(14828..15814)
                     /locus_tag="VQU30_001481"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001030014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-related sulfurtransferase"
                     /protein_id="HET2447571.1"
                     /translation="MAKDIRVLLYYLYTPIENAEQFAADHLAFCKSIGLKGRILVADE
                     GINGTVSGDYETTQKYMDYVHSLPGMEELWFKIDEENEQAFKKMFVRYKKEIVHLGLE
                     DNDFDNDINPLETTGAYLSPKEFKEALLDKDTVVLDTRNDYEYDLGHFRGAIRPDIRN
                     FRELPQWVRDNKEKFMDKRVVVYCTGGVRCEKFSGWMVREGYKDVGQLHGGIATYGKD
                     PEVQGELWDGKMYVFDERIAVDVNHVNPTIVGKDWFDGTPCERYVNCGNPFCNRRILT
                     SEENEDKYLRGCSHECRVHPRNRYVSKNELTQAEVIERLAAIGESLDQAATV"
     gene            complement(16086..17561)
                     /locus_tag="VQU30_001482"
     CDS             complement(16086..17561)
                     /locus_tag="VQU30_001482"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000800432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3502 domain-containing protein"
                     /protein_id="HET2447572.1"
                     /translation="MKNWKKYAFASASVVALAAGLAACGNLTGNSKKAADSGDKPVIK
                     MYQIGDKPDNLDELLANANKIIEEKVGAKLDIQYLGWGDYGKKMSVITSSGENYDIAF
                     ADNYIVNAQKGAYADLTELYKKEGKDLYKALDPAYIKGNTVNGKIYAVPVAANVASSQ
                     NFAFNGTLLAKYGIDISGVTSYETLEPVLKQIKEKAPDVVPFAIGKVFIPSDNFDYPV
                     ANGLPFVIDLEGDTTKVVNRYEVPRFKEHLKTLHKFYEAGYIPKDVATSDTSFDLQQD
                     TWFVREETVGPADYGNSLLSRVANKDIQIKPITNFIKKNQTTQVANFVISNNSKNKEK
                     SMEILNLLNTNPELLNGLVYGPEGKNWEKIEGKENRVRVLDGYKGNTHMGGWNTGNNW
                     ILYINENVTDQQIENSKKELAEAKESPALGFIFNTDNVKSEISAIANTMQQFDTAINT
                     GTVDPDKAIPELMEKLKSEGAYEKVLNEMQKQYDEFLKNKK"
     gene            complement(17665..18588)
                     /locus_tag="VQU30_001483"
     CDS             complement(17665..18588)
                     /locus_tag="VQU30_001483"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001075101.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HET2447573.1"
                     /translation="MAKKKIKKEKIDNVGIHSFSKKADIFFSIISGLIALSCILPFVF
                     VIIISVTDEKSLLQYGYSFFPSQFGLDGFEFLAQFKDKILQALFISVFVTVVGTLTNV
                     FITTTYAYAISRTTFKYRRFFTIFVLLSMLFNAGLVPGYIMVTRVLQLGDTVWALIVP
                     MLLSPFNIILMRSFFKKTIPEAILESARIDGASEARIFFQICLPLSLPGIATITLLTA
                     LGFWNDWFNALLYIKSDNLYPLQYLLMQIQQNMDYIAKAVGLTGQLGVALPKETGRMA
                     MVVVATLPIAILYPFFQRYFVKGLTIGGVKE"
     gene            complement(18602..19531)
                     /locus_tag="VQU30_001484"
     CDS             complement(18602..19531)
                     /locus_tag="VQU30_001484"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000714575.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HET2447574.1"
                     /translation="MKKFSKTLRDNWIFLLMVLPGALWLILFFYIPVFGNVVAFKDYH
                     MTSNGFIDSIINSKWVGLDNFRFLFSSRDAFIITRNTVLYNLGFIFLGLVVSVGIAII
                     LSELRSKRMVKIFQTSMLFPYFLSWVIISFFTDAFLNIDKGVFNHLLESLGLKEVNFY
                     ADLGIWPYLLLFLGIWKGFGYSSVMYYATIMGIDPTYYEAATVDGASKWQRIRNVTIP
                     QLTPLVTVLTILAVGNIFRADFGLFYQIPHNAGQLYNVTNVLDVYVFNGLTQTADIGM
                     AAAAGLYQSVVGLILVILSNLLARRVDPNSALF"
     gene            complement(19850..20200)
                     /locus_tag="VQU30_001485"
     CDS             complement(19850..20200)
                     /locus_tag="VQU30_001485"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000148255.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2447575.1"
                     /translation="MTGVSNPTTDSARLVLAEAKKAFADDSLTEQGLRDILQTVKDAI
                     ASLESIKESQSATKDGGQTAGKETADKDVLENSQEELQKAVLFLADEKGSEHTEAELI
                     DNLKEVIAKLKANA"
BASE COUNT         6271 a         4401 c         3710 g         6242 t
ORIGIN      
        1 ccatcaaatt taccgtctac gatatctaaa ccatatgcaa tggctcctcc taatgagaaa
       61 acttcagcaa cagtagccgc aatattaaga gcattagtaa tagttgccat actaactcca
      121 ccaatatatc ttgttatagc acttctaacg actcggctca tcataccacg attagcaatt
      181 aactttttaa tggcatatgt ctggtatact gacatccctc cagaaactgc agctgcagca
      241 atattatcac gtttgttcca ccagttacaa ccaacaccac ccccatcaag atacatcatc
      301 tcttcttgct caagaacaac ataattattt ggtaatacga gttccattta ttttctcctt
      361 ttttattaag catagttagg atcgtttcct aacaagtgat cgttgacttt gtttatagca
      421 cttagttacc tagataagat atcctttagc ttgcttccaa aatttaagtc tgcacctata
      481 atatgagttc atattagtac tgctaaatcc tatctatagt aatgtcaaac acctaaataa
      541 agtcatctct ccaattcatt caagaaatga agaaaggcaa aaaatcttta aaataagaaa
      601 agtgcatatt atcaggtgtt caaaaatctt gataatatgc gttatataat agaaaaattt
      661 actcaatttc actttcaaat tgagtttttt cccaacctcg tttttaattt atatcttcaa
      721 taaaatctaa tgacctagtt gatatgtcat atggaataat attatttaat ctgtaatttt
      781 tttaaaaaac ttaataataa atttgctcca ctgattgcta tcaatatttc aattggtaaa
      841 aaatagtaat tccaaataaa atgagaaatc agcaatgata gaaaaataac aatatcaatt
      901 ttcctgttgt tgacatactc tgtaatttta tggtacagga atgcaacaat aactgaaatt
      961 aaaacaacca tcataatact attatcctat tctcaattga ttatcacgtc gcccatccca
     1021 gccatcaata atattggtaa aatccaatca gctccagcac caattccagc agatgcaata
     1081 cttctaataa cagtatttgc aaaagcattt ccaatatgaa ttcctaatac tcctaaacct
     1141 ttaacaatcc cagctaccag tgcggagcgt aatccataag atgcaagaac tagttgaagg
     1201 cctccacctc ctgctgctgc taatgctgca tatgctgcac cagtaatggc tcctgtaatt
     1261 gcccacctgg gtatatatat agccccccca tcaaggtaca tcatctcttc ttcatcaatc
     1321 acaacataat tatttggtaa tacgagttcc atttattttc tcctttatac tatgtaatac
     1381 cacaaaatga ttttgaccta aatcattctt aacttgaaga atcgcaggaa atgttaattt
     1441 tggagtcaaa tcttccagtg ctactcgaac agcttttact gtaaaattca acttattcag
     1501 acctgaaaca ataccactga cagtcgttcc atacatgtct gtaccaataa tttcccgaat
     1561 cttcatgatt gatagttcct ttttgtaaga taaaagaact gttgaaacaa ctgccgcagc
     1621 acaatctgac tgatcatgtt gcatcgtaca aggatatttt tttaacatag aaatactcaa
     1681 ttctttagaa ttaatctaac ttttctttga tgtcacccaa acctcaatca ctgcccagta
     1741 gttcttgaat cagtttattt tcaatcgtat cattctttgt tcttgatatc tttccaagca
     1801 ttgtagtaca gcagattttt gtccaaggac taagcctcct ttaacaactc aagctccctt
     1861 acattatatc gaccagcccc atggaaagat tatggccaga ctaatcaatg atataataca
     1921 tactagaata caaaatattt ttttattcat actttttctc ctatctttat tttctaccta
     1981 catcatacct cttattaagc tcattttaaa attacgttaa cttttttcac aaatttattt
     2041 cgactttctt ttttactttt tacattgcta tgatacaata tttttaacaa aattttattg
     2101 tttgttaact tttttcacag aaaggagaaa atcatgcgtt atgatttcgg aaaggtctat
     2161 aaagaaatac gtgagtcaaa ggggctgacc caagaagagg tctgtggggg tgttctctca
     2221 agaaccagct tatcaaaaat cgaaagtggc aagacaaccc caaaatatga aaatatggaa
     2281 tttcttctcc gtcaaatcaa tatgagtttt gaagagtttg aatatatctg tcaactttat
     2341 caaccaagtc aacgcacaga gattatgcaa acctatctca atatgcgttc cattatcggg
     2401 accagcgatc ttgtcaattt atttcaaaaa tgccaagact acctcaagac ccaccacgat
     2461 ctccctatag aagaaatcag agatatgctt gaagttgtta tttatctccg tcaacacggg
     2521 gcaggggaac tatcaaaaca cgcagaacag gttgtcaaaa aactttggaa aaaaattgaa
     2581 aaacaagata catggtatga gagtgatcta aaaatcctca ataccattct tttcagtttt
     2641 cccattgaat acctccatct catcactgga aaaatattgc aacgcctaga agtctataaa
     2701 aactatcaac atttatatga cttgcgaatg acaattctat taaacctttc cacactctat
     2761 ctatacaatc aagataaaaa catgtgtaag caaatctgct acactttact ggaggacgcc
     2821 aagaataaga aaagctacga taggctggct atctgctatg tccgtattgg gatttgtaca
     2881 gacgattcta aacttatcca aaaagggttc tcccttctgg agctaaccga ggaaacttct
     2941 atgctgtctc atctcaaaaa agaagtagag atctattacc aagcgaagga aagataaaaa
     3001 agccgaggga tttcctcgac tctttacata ttatttgttc gttagttctt aataccagcc
     3061 attgttaagc cagaagtttt tagcagcagt ccatgaaccg taacgtcctg caacgtaggc
     3121 atctgctaca cgttcttggt tttcagctga gtagtcaccg ttcaggtatg aatctgttaa
     3181 ttggtaacgt ccgatataac gtccatttgt agctgtatag ctaccacctg attctttttg
     3241 agcgatccat tctttggctt ctgcttcaga tccgcttaca gttgaaacaa ctgtttcact
     3301 tactactgga gctgaaacag tttcatcttg agcggctggt gccgcataag tagctggcgc
     3361 tggtgttgca acaggcgcta cagggccatc gataaccaac tcttgatcaa cataaatcaa
     3421 atgaatgtta tcaatgtggt tgttttctgc caatttttca actgttgtgt tgtgagtttc
     3481 agcgatttct gaaagtgtat caccttcttt aacagtgtaa gttgatgatt cttgagcaga
     3541 tacaaatgat ggagaaaata ctgcaaacaa ggcagctact cctgcaagag ttgctttaat
     3601 ctttttagtt attgatttca tattcgaaaa ttctccttct ttctatagtt ctatcatacc
     3661 ctttaaatat tactgtttct tgacactttt atgtagaaat attacaaaat tattttttat
     3721 ttccctaaat aaggtgtttt ttgtcataaa agatactatt tttatgctat ttgaggtatt
     3781 agaaaggttt tcatccacaa ttaaagccaa gcccctcatt ctttgatata atagagataa
     3841 gaatttttat aaggggaaac tgatgaaatc acttcgtttt caatctgtct ttgatatcat
     3901 cggaccagtt atgattggcc catctagtag ccataccgct ggtgctgttc gtattgggaa
     3961 gattgtctct tccatttttg atgatactcc gacagaagtt gaattccaac tttttaactc
     4021 atttgccaag acctatcgtg gtcacggaac agacctagcc cttgttgcag gtattttagg
     4081 aatggataca gatgatcctg aaattccaaa tagtctggaa attgcccaca agcgtggtat
     4141 caagattgtc tggaccattc agaaagacag caatgcccct caccctaaca ccactaaaat
     4201 tactgttaaa aatgcccaca agaccatcag cgtgactggt atttctatcg gtggaggaaa
     4261 tattcaggta accgaactca atggttttgc cgtctctctc aatatgaata caccgactat
     4321 catcatcgtt catcaagata ttccaggtat gattgccctt gttacagagg cgctttcccg
     4381 ctatggtatc aatatcgccc agatgaatgt cactcgtgaa aaagctggtg aaaaagccat
     4441 tatgattatc gaagttgaca gtcgcaactg tgatgaggct atcgaagaaa ttcgaaaaat
     4501 ccctcatctc cacaatgtca atttctttaa ataggaggaa gcatgtttta ttctatcaaa
     4561 gaattggtcg agcaagcaga tctggacttt caaggaaatg tcgcagaact catgattaca
     4621 acagagtttg aattgaccgg tcgcgaacgt gaagaagtct tccttctcat ggaacgcaat
     4681 ctggaagtta tgaaagcctc tgtccaactt ggcctcaatg aaaataaatc tcgtagtggc
     4741 ctgacaggtg gagatgctgc caaattggat cactacatca aaaacgaaaa aactttatca
     4801 gattacacga ttctctctgc tgcccgaaat gctatcgcag tcaatgaaca caatgctaaa
     4861 atgggcttgg tctgcgctac tcctaccgca ggaagtgccg gttgtctccc ttccgttctc
     4921 actgctgcta ttgaaaaatt agacctcagc cacgagcaac aattggattt cctctttgct
     4981 gctggtgcct ttggactagt catcgcaaac aatgcctcca tctcaggtgc tgagggtggg
     5041 tgtcaagctg aagttggttc agcctctgct atgagtgctg ccgccttgac tctggctgca
     5101 ggtggaacac cttatcaggc cagtcaagct attgcctttg tcattaaaaa tatgctaggc
     5161 ctcatctgtg accctgttgc aggtttggtc gaagttccct gtgtcaaacg taatgccatg
     5221 ggagctagct ttgctttcat cgcagcagac atggccttgg caggtatcga atctaaaatc
     5281 cctgtggatg aagtgatcga tgccatgtac caagtaggag caagcatgcc aactgccttt
     5341 cgtgaaacag ctgaaggtgg actcgctacc acccctactg gtcgtcgcct ccaaaaagag
     5401 attttcggag aataagctta tcaaatagga gaaaccatga cctctatcac agcgattttt
     5461 ttcgatttgg atggaaccct cgttgatagt tctatcggga ttcacaatgc ctttacctat
     5521 acctttaaag agctgggggt gcctagccct gatgccaaaa ctattcgtgg ttttatggga
     5581 ccacctctcg aaagtagttt tgcgacctgc ctgtccaaag accaaatttc tgaagccatg
     5641 cagatatatc gttcttacta taaggcaaaa ggcatctatg aagctcaact ctttcctcag
     5701 attatagact tgcttgagga gttatcgagc agttatccac tctacatcac cacgacaaag
     5761 aatacatcta ctgctcaaga catggccaaa aacttggaaa tccatcattt ctttgatggt
     5821 atttatggtt ctagccctga agcaccccat aaggcagatg tcattcacca agccttacag
     5881 acacatcaac tagcaccaga acaagccatc atcatcggag ataccaagtt tgatatgctg
     5941 ggagctcgag aaacaggtat tcagaaattg gccgtcactt ggggatttgg agagcaagca
     6001 gatctactaa actatcaacc tgattatatc gctcacaaac ccttagaagt tttggcgtat
     6061 tttcaatagc atagactggg cgacaactct atttcagaag aaaatgaagt aatactcaat
     6121 gaaaatcaaa gagcaaacta ggaaactagc tgcgggctgc tcaaaacact gttttaaggt
     6181 tgtagatgga actgacgaag tcagctcaaa acactgtttt gaggttgtgg atagaactga
     6241 cgaagtcagc tcaaaacact gttttgaggt tgtggataga actgacgaag tcagtaacca
     6301 tatacggcaa ggcgacgttg acgtgatttg aagagatttt cgaagagtat aagtctctac
     6361 ataataaaac gcatattacc aaggttattt aacttgataa tatgcgtttt tcttttttat
     6421 tcaatgtggg ttgtttgatt agcaaaggcg ataatagctt gcttcaactc atctccactg
     6481 agagtgcgga actctccaat cttttgattg atggattcta aaggcatgac attaacctta
     6541 ccaacgaaaa tcttatccat aacttgatta tcaacgagtt cggttgatac caagagttct
     6601 tcgtagagtt tttcacctgg gcggattcca acttcaacga ttggaatttc actttcagtg
     6661 tggccactta gaagcaccat cttcttggcc aagtcataaa tcttgactgg tttgcccata
     6721 tcaaggataa agacttcccc atctttggca taagcaccag catggataac cagacggcta
     6781 gcttctggaa tggtcataaa gtaacgggtc atgcggaagt ctgtcaccgt tacaggccca
     6841 ccttcagcaa tctgacgttc aaagactgga atgacactac cacggctacc aagaacattc
     6901 ccaaaacgaa ctgcacagta ggttgattgg ctacgttggt taaagccagt gacaatcaac
     6961 tccgccacgc gcttggttgc tcccataaca tttggtggat tgactgcctt atctgtcgaa
     7021 atcataacca tcttaggcac cttggcttca tcaacggctc tagcaacatt gtaagttcca
     7081 cggatattgt ttttgaaggc ttcttttgga ttgcgctcca tcataggaac atgcttgtgg
     7141 gctgccgcat gataaacaat agcaggtttg tactgctcaa agacttgcaa caaacgatca
     7201 tagtcttgaa tgtccgcaat cacaggtaca taatcaatcc cttggaactt acgaatcaat
     7261 tcatgataaa caaggtagat tgagttttcc ccatgaccga gcaagacaat gcgttcagga
     7321 ttgaagcgac taacttgacg acagatttca gaaccgattg aacctccagc tcctgtgact
     7381 aagatggtct tacctgtcag ttctgcaccc agacgcgatt cgtcaagacg gatttcctga
     7441 cgacccaaaa ggtccgtaat atcaattttt tggaagccag tacctgcttg gtgaaggccc
     7501 tgaacaacag tttcaacctt aggcatcttg taacatttga cacccagctt attacacatc
     7561 tgcaagatac gctcatattc tgacggatcc agcgacggaa tcgcaacgat gacacgctcg
     7621 atttgatggc gtttggctaa ttcaggcaga ttgtcataag agcccaaaac aggaatacca
     7681 ccaagttttt gacccttttt cttagaatcc ttatccaaaa taccgaccag ttctaattca
     7741 ctggttggat gttggtaact atccataaag agagccccac catcaccggc accaatcaag
     7801 aaggtccgac ggtgttctcc atcaccacta ccttttttgc gtctggagta gattaactgc
     7861 caagtaatcc gtggcaataa aatcaagaag gtactcaaca agataaagag aatgataaaa
     7921 cggatggaga agagtggcaa gaaggcataa cagatactat atgacaagac actgctagca
     7981 gtcacaccaa aaaagatttt catgaaatcc gtaatcttgc tgtaacgact aatactcgcg
     8041 ctcaagcccc aaaaatcaac catcaattga tagaacagga aggccaaact cgtatagata
     8101 atgtagtcaa caggtgctgg attaatcagc ccataaaata aaatataaga tacaatgatg
     8161 gaaaccacca tactgaaaat atcaaatatt ccccagaaaa cctgcttttg ttgtttattt
     8221 aaaatttcca ccagatcaat cacataatct gtgagttttt tattcataga aatttactcc
     8281 tccttaaaat agttctacta tattgttatt atagcacatt ttaatttatt tggcttattt
     8341 ttccaaataa attactgttc ccttgtactc cttcttccat ttaaatcctc taattaaacc
     8401 tacaatcgtc ccaaggccat aagcaaagtg aatggaaaat aaaagaaagg gcatcacaat
     8461 tagaaatcca tttttatgtt ttaataaagt cagcaaagtg agtaatgaca gtaatgataa
     8521 aagtagaaaa taggcaccta atagtaaagt tatgaatacg aatgtgatcg gtaacaatgc
     8581 tagactaaac acaagactca aaacaaataa acaaggaaca taatgaaata atgataaaca
     8641 cttaaactga acatgacttg tcaagccaat ccacaaacca tttgaatact tttgatgcag
     8701 cattttcttg aatgttggtc gaatatactg ataagataga atacttgggc tatagcggat
     8761 tttataacca tgttctcgaa ttctataatg aatatcatta tcttcagttc ggccaagttg
     8821 ctcatttact aaaccaacct tctggaaaac ctctcgttta tacatcccat gaaaaataga
     8881 agaaacatat ctatcctcgg aactatttcg ataattggca atgctactgc caaacatatt
     8941 ttcctcaaca agatgcaagg tctctgccca ttttcctttt cctttgacaa tcgtcggtct
     9001 aggccctcca cagacaaatt caccttgttg aataacagcc acattgttca ttacaaaact
     9061 ctcagtaact tttgaatgag catcaatttt taaaataagg ccccctacag aatgcttaac
     9121 tcccaggtta aaaccactag cttgattttt cttaggattg ttatacaatc taattgagtt
     9181 aaactctgca tcttctttta taaattgctg aatgatagct gtggtcccat ctgtggacat
     9241 agcatttata aatagaattt caatattctc tttaggatag gtttgatttt ttaagtcttc
     9301 aattagacca ggcagatatt tttcttcatt gtatgcactg attacaatgg atacgagaag
     9361 actttcaaca ttttgagtca ctactactct cctgaatttt cccttccacc attctatcat
     9421 aattttcaag acttttccat ttttatcttg aaagccagaa accttacttg acattatagt
     9481 gaaaaagcct taaaataagc tgttattaaa atcagctaga agagatatta tatgaaaaag
     9541 caatcactct tttttgttcc aggtattatc ctgattggtg tttccttgcg aactcctttt
     9601 actgttttac ccattatttt gggaaatatt tcgcaaggtc tggaggtaga agttagttcg
     9661 cttggtgtct tgaccagcct gcctctcctt atgtttaccc tcttttcacc attttctacc
     9721 cgactggctc agaaaatcgg cttggagcat ctcttcacct acagcctctt cttcttgacc
     9781 atcggctcac ttattcgact aatcaatctg cccctgctct atctaggaac cttgatggtt
     9841 ggggcaagtg tcgcagtcat caatgtcctg cttcctagtc ttatccaagc caatcaacca
     9901 aagaaaattg gttttctgac caccttatat gtaacgtcta tggggattgc aacggctctg
     9961 gcttcctatc tagctgtgcc cattacacaa gccagttctt ggaaaggact tatcctcctc
    10021 ctcacgttac tctgtctagc aacttttttg gtctggctcc caaatcaccg ctataatcat
    10081 agactagctc cacaaaccaa acaaaaaagt caaataaagg tcatgcgtaa taaacaggtt
    10141 tgggcaatta ttatcttttc aggttttcaa tccttgatct tttacaccgc catgacctgg
    10201 ttacctacca tgtctatcca tgcaggtcta tccagtcacg aagctggctt gctgacttct
    10261 atcttatctc tgattagcat tcctttttca atgaccatcc caagcctgac aaccagttta
    10321 tctactcgca accgtcagct catgctcact ctggtttcac tagctggtgt ggtcggcatt
    10381 tccatgctct ttttcccaat caataatttc atttactggc ttgccatcca tctcctcatc
    10441 ggaaccgcaa ccagcgccct cttcccttat ctcatggtca acttttcact caagaccagc
    10501 gcccctgaaa agacagccca attgtccggc ctatctcaaa caggaggcta tatcctagca
    10561 gcctttgggc caaccctctt tggttacagt tttgacctat tccactcttg ggtaccagct
    10621 gtagctgccc tcttgctcat cgatatcctg atgactgtgg ccctctttac agtggacaga
    10681 gcggataaga tcctttaaac ttctagtttt agctagaagt tttttatata taaaaatttt
    10741 acacatttct cttgacaggg ctttctttta gatgtacaat gtatgtgtag aaaaattata
    10801 tataaaaatc ttacacatta gaaaaggagg tttcccatgt actttccaac atcctctgcc
    10861 ttgattgaat ttctcatctt ggctgtactg gagcagggtg attcttatgg ttatgagatt
    10921 agccaaacca ttaagctgat cgctaatatc aaagaatcca cactctatcc cattctcaaa
    10981 aaattggaag gcaatagctt tctgacaacc tattctagag agttccaagg tcgcatgcgc
    11041 aaatactact ccttgacaaa cggtggtata gagcagctct tgaccctaaa agatgaatgg
    11101 acactctata cagacaccat caatggcatc atagaaggga gtatccgcca tgacaagaac
    11161 tgaatacctg actcagctag aactctatct caagaaacta cctgaagctg accgtatcga
    11221 agccatggac tatttcagag agctctttga cgatgctgga gtcgaaggag aagaagaact
    11281 catcgctagt ttgggaactc ccaaagaagt ggcccacgaa gttctatcca atcttctcga
    11341 taaaaaaatc aatgaagcac ccgctcaaaa aaataaccga caaattttac atatcgcctt
    11401 gttagccctc cttgcagcac ctatcggcat tcctctggga atcgccatcc tcgtgaccct
    11461 gttcgcaatc cttgtagccg ctttgactgt cattctggct ttctttgcag tttccatact
    11521 gggtatcatc ggcggattcc tatttttagt tgaaagtttc actgtcctcg cccaagccaa
    11581 atcagccttt atcttgattt ttggttctgg tttactggct atcggtgctt cttcgctagt
    11641 tttacttggc atttcctatg tagctcgctt cttcggtcta ctcattgttc gtctggtaca
    11701 atttgttctt aaaaaaggaa agagaggtaa tcagcatgcg taaatggaca aaaggatttc
    11761 tcatctttgg tgtggtgact accgttatcg gctttatcct gctttttgta ggtatccaat
    11821 ctgacgggat taagagccta ctttccatgt ccaaagaacc tgtctatgat agccgtacgg
    11881 aaaagctaac ctttggcaag gaagtcgaaa acctagaaat tactctccac caacacacgc
    11941 tcaccatcac agactctttc gatgatcaaa tccacatttc ttaccatcca tctctttctg
    12001 ctcaccatga tcttatcacc aatcagaacg atagaactct gagtctcact gataagaaac
    12061 tgtctgaaac tccgtttctc tcttctggaa ttggtgggat tcttcatatc gcaagtagct
    12121 actctagtcg ttttgaagaa gttattctcc gactaccaaa agggagaact ctaaaaggga
    12181 tcaacatctc agccaatcgc ggacaaacca ccatcataaa tgctagcctt gaaaatgcga
    12241 ccctcaatac aaacagctat atcctccgaa ttgaaggaag tcgtatcaaa aacagtaaac
    12301 tcacaacgcc caatatcgtt aatatctttg atacagttct tacagatagt cagctagagt
    12361 caacagagaa tcacttccac gctgaaaata tccaagtcca tggtaaggtt gaactgactg
    12421 ccaaagatta tctcagaatc atcctagacc agaaagaaag ccaacgaatt aactgggaca
    12481 tctcaagcaa ctatggttct atcttccaat tcacaagaga aaagcctgaa tcaagaggta
    12541 cggaattaag caacccttac aaaactgaaa aaaccgatgt caaggatcaa ctcattgcga
    12601 gatctgatga taatattgat ctaatatcca caccaagcag acgttgacaa aaacgcttac
    12661 atctgctact atggaagcat atttatctaa ctaaaaagga ggttctacca tgaaacaaga
    12721 atggtttgaa agtaatgatt ttgtaaaaac aacaagcaag aacaagcctg aagagcaagc
    12781 tcaagaggtt gcagacaagg ctgaagaaac gatagccgat ctcgatacac caattggaaa
    12841 aaatactcaa gtagaggagg aagtctctca agctgaagtc gaactggaaa gccagcaaga
    12901 agagaaaatt gaaactcctg aaggcggtga agcgagaaca gaaatagaag aaaagaaggc
    12961 atctaattct actgaagaag agccagacct ttctaaagaa acagaaaaag tcactatagc
    13021 tgaagagagc caagaagctc ttcctcagca aaaagcaacc acgaaagagc cacttcttat
    13081 cagtaaatct ttagaaagtc cttatatccc cgaccaagct ccaaaatcta gggataaatg
    13141 gaaagagcaa gtgcttgatt tttggtcttg gctagtggaa gcgatcaaat ctcctacaag
    13201 taagttggaa acaagtatca cacacagtta cacagccttt ctcttgctca ttctgttttc
    13261 tgcatcttcc tttttcttta gtatctatca catcaaacat gcttactatg gacatatagc
    13321 aagcattaac agtcgcttcc ctgagcagct agctccttta actctttttt ctatcatctc
    13381 tatcctagta gcgacaacac tcttcttctt ttcattcctc ttgggtagtt tcgttgtgag
    13441 acgatttatc caccaggaaa aggactggac gctagacaag gttctccaac aatatagtca
    13501 actcttggca attccaatct tcctcactgc tattgctagt ttctttgctt tctttgatag
    13561 cctacgattt acggccctct tgtgtgtgat tagcattgga atcattctgc ttgccagtct
    13621 ccatatcatt acaagaccaa gtcaagcaag tgaaaccgac tccttctatc aattattctt
    13681 gtctgtcctt gtgaacggag ttattatcct cctcttcttt gtagctgaag tggcactgat
    13741 tggagattat cttcgtatct tggcctttct ttaaaattca atcctgtcat ccttggcagg
    13801 attttttcta tgtcaaaaaa gcaagtcgat tgacctgctt ctgctttact tttcttgtgc
    13861 taatgtttta aaatctttgt ctaatatggg ttgcacttct atttgattgg cgtctagttg
    13921 gtggtaaaaa gatgggggta atacctctaa gaattttgca tagtccaagc gagcaatggc
    13981 ttcatagtct tctggtttag agccatctcc tgtgatttga accaagtcaa tctcccactg
    14041 cacttcctta tccaccaatt gctcaatata ggctgcagga acaaacggtt ctctcggtaa
    14101 aactgtcttg actccttgag ctagatggta aacgccatgc acttttcctt ctccatcctg
    14161 atagaaggaa actctcgcaa agtaggcatc tgtctcttga accgcacgca cacgcgcttc
    14221 aaactgagcc aaaccatctg cctctaaaaa gcttttcaag ttctcacgac taaagaaaat
    14281 aggattaaaa attccttggc aaatcgtaaa acgagctaca gggtctgcta gataggcttg
    14341 aatacttgct tggaaataag cttcaaaatc aaaaccatct agcccttcaa tatcagtccc
    14401 tgtataagca agcaaagcat ctaaaaatga cttgataatc tgccagtctg tctctgttag
    14461 taggtcagga agatcgacac ggtaagcctt ttgaccatca gcataactga ccttaaaaag
    14521 aaattgtgat tgccccacta tcgcacactc aatatactcg agacgattaa gaggctgacg
    14581 gagatagact acatcataga tatgtgactc caaaccgtct agcaatgcca agatcgactt
    14641 ggcattcaaa atctcttgtt ctcctaaaat gctctgttta tttggaataa aaaatgtttt
    14701 cgccataact ggactccttt gaaatcgctt acatacagta taccttattt ttctgaaaga
    14761 tacagaaaca aactttagat ttttgagtac aaagcataga aaaacagccc ctgaggactg
    14821 tttgatctta tacagtagct gcttgatcca agctttcacc gatagcggct aggcgctcga
    14881 tcacttcagc ttgtgtcaat tcattttttg aaacatagcg gttacgtggg tgaacacggc
    14941 actcgtgtga gcatccacga aggtacttgt cttcattttc ttctgatgtc aagatacgac
    15001 ggttacagaa gggatttcca cagttgacat aacgttcaca tggtgttcca tcaaaccagt
    15061 ctttccctac gatggttggg ttgacatggt tgacatcaac ggcgatacgc tcgtcaaata
    15121 cgtacatttt tccatcccaa agctcacctt gaacttctgg gtctttaccg taagttgcga
    15181 ttcctccgtg caattggccg acatctttgt agccttcacg gaccatccag cctgagaatt
    15241 tctcacagcg aacgccacct gtacagtaaa ccacgacacg cttgtccatg aatttttcct
    15301 tgttatcacg gacccattgt ggtaactcac ggaagttgcg aatatctggg cgaatagctc
    15361 cacggaaatg tcctaggtcg tactcataat cgttacgtgt gtcaaggaca acggtatctt
    15421 tatcaagaag cgcttctttg aactcttttg gagacaagta agcacctgtt gtttcaagtg
    15481 ggttgatgtc attgtcaaag tcgttgtctt ccaaaccaag gtggacaatt tctttcttgt
    15541 agcgaacaaa catcttcttg aaggcttgtt cattttcttc gtcaatcttg aaccagagtt
    15601 cttccattcc tggaaggctg tgaacgtagt ccatgtattt ttgagttgtt tcatagtcac
    15661 ctgaaactgt tccgttaatt ccctcgtcag cgactaggat acggccttta agaccgattg
    15721 atttacagaa agccaagtgg tctgcagcaa attgctctgc attttcaatt ggagtataaa
    15781 ggtagtaaag taagacacga atatcttttg ccataagatt tgttctcttt tctattctta
    15841 aattttctaa attttttatt tatccatact agtatacctg cttgagaaaa cgaatgcaat
    15901 ttatttgact ggaaattgta gaggattctc gaaatttcct gaatggttaa aataaggaca
    15961 agagaaaaca tggatatcta tatccttgtg ccaaaaaaac cactgccctc cccagaccaa
    16021 cctgaggaaa gcagtgattc ttattttagg agttaggaat gaatacacga aatcaattta
    16081 gctgattatt ttttgttttt caagaattca tcgtattgtt tttgcatttc gttcaatact
    16141 ttttcgtagg caccttcaga tttcaatttt tccatcaatt ctggaatcgc tttatctggg
    16201 tctacagtac cagtgttgat agctgtatca aattgttgca ttgtgttagc aatagctgag
    16261 atttcagatt tcacattgtc agtattgaag ataaatccaa gcgctggaga ttctttagct
    16321 tctgccaatt ctttcttaga attttcgatt tgttggtctg taacgttttc gttgatgtaa
    16381 aggatccagt tgttaccagt gttccatcca cccatgtgag tgtttccttt gtagccatca
    16441 agaacgcgaa cacggttttc tttaccttca attttttccc agttcttgcc ttctggaccg
    16501 taaacaagac cgttcaaaag ttctgggttc gtattcaaga ggttcaagat ttccattgat
    16561 ttttctttgt tcttagagtt gtttgagatg acaaagttag caacttgtgt tgtttggttt
    16621 ttcttgatga agttagtgat tggtttgatt tggatatctt tgttggcaac acgtgaaagc
    16681 aagctgttac cgtagtcagc tggtcctact gtttcttcac gaacgaacca agtatcttgt
    16741 tgaaggtcaa atgaagtatc gcttgttgcg acgtcttttg gaatgtagcc agcttcatag
    16801 aatttgtgaa gagtcttcaa gtgttctttg aaacgaggca cttcgtaacg gtttacaact
    16861 ttagtagtat cgccttcaag gtcaataacg aatggaagcc cgtttgctac tgggtagtca
    16921 aaattatcag atgggatgaa aactttacca atagcaaatg gtactacgtc tggagctttt
    16981 tctttgattt gtttcaagac tggctcaaga gtttcgtaag aagtaacacc tgaaatatcg
    17041 ataccatatt tggcaaggag agttccgttg aaggcaaagt tttgagatga tgctacgttg
    17101 gctgcaactg gtacagcata aatcttacca tttacagtat tacccttgat ataagctgga
    17161 tcaagtgcct tgtaaaggtc tttaccttct tttttgtaca attctgtcaa gtcagcataa
    17221 gcaccttttt gagcatttac aatatagtta tctgcaaagg cgatatcata gttttcacca
    17281 gatgatgtga taactgacat tttcttacca tagtcacccc agccaaggta ttggatatcc
    17341 aatttggcac caactttttc ttcgatgatt ttgttggcat ttgctaacaa ttcatccaag
    17401 ttatctggtt tgtcaccgat ttggtacatt ttgataacag gtttgtcacc tgaatcagca
    17461 gcttttttgc tgttacctgt caaatttcca caagcagcaa gacctgcagc cagagcgact
    17521 acactagcag atgcaaaagc atattttttc cagtttttca tgataaaaac tccttttttt
    17581 atttttaaac ttataaacaa tgtaatgatc ttaacttcac acaagggaag ttgggaactg
    17641 agaaatgttc tttttcaata agcactattc tttcacacca ccgatagtca aaccttttac
    17701 aaagtagcgt tggaagaatg gatacaaaat cgcgattgga agggttgcta ccacaaccat
    17761 ggccatacga cctgtttctt tcggtagagc aactcccagt tgaccagtca agccgaccgc
    17821 tttggcaatg tagtccatat tttgttggat ttgcatgagc aaatattgca atggatacaa
    17881 gttatcactc ttgatgtaaa gaagggcgtt gaaccagtca ttccagaaac caagagctgt
    17941 caaaagcgtg atggttgcga tacctggtag tgacaatggc aaacagattt ggaagaaaat
    18001 ccgagcctca ctggcaccat cgatacgagc cgattcgaga atggcttctg gaatggtctt
    18061 cttgaaaaaa gaacgcatca agatgatatt gaatggtgag agaagcattg gaacaatcaa
    18121 ggcccaaaca gtgtcaccaa gctgaagtac acgggtcacc atgatataac ctggtaccaa
    18181 accagcgttg aacaacatac tgagaaggac gaagatggta aaaaatctgc gatacttaaa
    18241 ggttgtccgt gaaatagcgt aggcataggt tgttgtgata aagacatttg tcaatgtccc
    18301 aactacggtt acaaagacag agatgaagag ggcttgtagg attttatcct taaactgtgc
    18361 caaaaactca aaaccgtcta agccaaattg ggatgggaag aagctatagc cgtattggag
    18421 gaggcttttc tcgtctgtca ctgaaataat gataacgaat acaaaaggta ggatacaaga
    18481 gagggcaatc aaacccgaaa tgatactgaa gaagatatct gctttcttac tgaaggagtg
    18541 aatgccgaca ttatcaattt tttctttttt aattttcttt tttgccatat tctcctcctt
    18601 tctagaacaa agctgagttt ggatcgactc gtcttgcaag caagtttgat aggataacca
    18661 gaatcaaacc aacaacggat tggtaaagac cggctgctgc agccataccg atatctgctg
    18721 tctgagtcaa accattaaag acatatacgt ccaaaacgtt ggttacattg taaagctgac
    18781 cagcattgtg tgggatttga tagaagagac cgaagtctgc gcggaagata tttccgactg
    18841 caaggatggt caatacagtt acaagcggag tcaactgagg aatggttacg ttgcgaatac
    18901 gttgccactt gctagctccg tccactgtcg ctgcttcgta gtaggttgga tcaattccca
    18961 tgatcgtcgc atagtacatg acactgctat atccaaagcc tttccaaata cctaggaaaa
    19021 gtaggagata gggccagatg cccaggtcag cgtagaaatt gacttctttg agaccaagac
    19081 tttccaatag atgattgaac acccctttat caatatttag gaaggcatct gtaaagaaac
    19141 tgatgataac ccaagacaag aagtaaggga acaacataga agtttgaaaa atcttcacca
    19201 ttctcttaga acggagctcg ctgaggataa tggcaatccc tacagataca actaaaccta
    19261 gaaagataaa gccaagattg tagaggacag tatttcgtgt gataataaag gcgtctcttg
    19321 aactaaataa gaatctgaaa ttatcgagtc cgacccattt actatttatg atactatcta
    19381 tgaaaccatt actggtcatg tggtagtctt tgaaggcaac cacgttccca aatactggaa
    19441 tgtaaaagaa tagaatcaac cagagtgccc ctggcaaaac catcaagaga aagatccagt
    19501 tgtctctcaa tgtttttgaa aactttttca taatttcctc cctttttatt ttgatatcca
    19561 tctaaaaatt cttttttaga cttttgataa cgattacatt attagtatac tcctatttgc
    19621 aggttaggtt aaactcctaa ttatagaaaa aactccacaa attatgtagc agatttaaaa
    19681 ctttatcacc actatcaaac aaatgtccta aatcaattgt ttattttatc tctattagcc
    19741 cagtgatggc gtcactctgt tataagcatc caacaacggg gtatactgaa aaatctccag
    19801 actagggaac tcagcgatag ttcctaatct ggagattttt aatatgttat taggcgtttg
    19861 ctttcaactt agcaataacc tctttaagat tatcaatcaa ctctgcttca gtatgctcag
    19921 agcctttttc atctgccaag aacaaaactg ctttttgaag ttcttcttga gagttttcaa
    19981 ggacatcctt atctgctgtt tctttgcccg ctgtttgtcc tccatcctta gttgctgact
    20041 ggctttcctt aatggactct agggaagcaa tggcatcttt gactgtttgc aagatatcac
    20101 gtaaaccttg ctctgtcaaa ctatcatctg caaaagcttt cttagcctct gccaaaacca
    20161 gacgtgctga atctgtggta ggattcgata cacctgtcaa tgatctcaaa agattttcta
    20221 aagtttgagt ctgcttacta atactagact aaaatcaaaa agcattatat aacagtgata
    20281 tgaaatcaac taaagaagaa atccaaacta tcaaaacact tttaaaagac tctcgtacag
    20341 ctaaatatca taaacgcctt caaatcgttc tatagtaaaa tgaaacaaga acaggacaaa
    20401 tcgatcagga cagtcaaatc gatttctaac aatgttttag aagtagaggt gtactattct
    20461 agtttcaatc cattatattt cgtctgatgg gcaaatctta taaagagatt atagaacttt
    20521 tatagtagtt tgaaataaga tgtgaacaac tctatcagga aagtcaaatt aatttataga
    20581 aatattttag cagctaaggt gtactgttat agattcaata cact
//
LOCUS       DAVBBO010000042        20104 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ST1
            SAMEA2066453-rid20184263.denovo.042, whole genome shotgun sequence.
ACCESSION   DAVBBO010000042 DAVBBO010000000
VERSION     DAVBBO010000042.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2066453
            Sequence Read Archive: ERR351777
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 20104)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 20104)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980402.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980402.1
            Genome Coverage       :: 176x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:17:33
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,141
            CDSs (total)                      :: 2,104
            Genes (coding)                    :: 1,953
            CDSs (with protein)               :: 1,953
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 16S)
            partial rRNAs                     :: 1 (23S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 151
            CDSs (without protein)            :: 151
            Pseudo Genes (ambiguous residues) :: 0 of 151
            Pseudo Genes (frameshifted)       :: 73 of 151
            Pseudo Genes (incomplete)         :: 76 of 151
            Pseudo Genes (internal stop)      :: 40 of 151
            Pseudo Genes (multiple problems)  :: 32 of 151
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..20104
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2066453-rid20184263.denovo.042"
                     /strain="ST1"
                     /db_xref="taxon:1313"
     gene            complement(20..667)
                     /locus_tag="VQU30_001486"
     CDS             complement(20..667)
                     /locus_tag="VQU30_001486"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000345255.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiator protein A"
                     /protein_id="HET2447576.1"
                     /translation="MDFEYFYNREAERFNFLKVPEILVDREEFRGLSAEAIILYSILL
                     KQTGMSFKNNWIDKEGRVFIYFTVEEIMKRRNISKPTAIKTLDELDVKKGIGLIERVR
                     LGLGKPNIIYVKDFMSIFQVKENDLQKSKNLTSEVKDFNLRSKENELQEVKNLDSNYI
                     ENNKSKYSKREYSFGENGLGTFQNVFLAAEDISDLQIIMNSQLENYIRLPAKLES"
     gene            complement(776..1294)
                     /locus_tag="VQU30_001487"
     CDS             complement(776..1294)
                     /locus_tag="VQU30_001487"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013852041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ClbS/DfsB family four-helix bundle protein"
                     /protein_id="HET2447577.1"
                     /translation="MRTYENKEELKAEIEKTFEKYILEFDNIPENLKDKRADEVDRTP
                     AENLAYQVGWTNLVLKWEEDERKGLQVKTPSDKFKWNQLGELYQWFTDTYAHLSLQEL
                     KAKLNENINSISAMIDSLSEEELFEPHMRKWADEATKTATWEVYKFIHVNTVAPFGTF
                     RTKIRKWKKIVL"
     gene            complement(1521..2390)
                     /gene="rsmI"
                     /locus_tag="VQU30_001488"
     CDS             complement(1521..2390)
                     /gene="rsmI"
                     /locus_tag="VQU30_001488"
                     /EC_number="2.1.1.198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001166894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA
                     (cytidine(1402)-2'-O)-methyltransferase"
                     /protein_id="HET2447578.1"
                     /translation="MQIQKSFKGQSPYGKLYLVATPIGNLDDMTFRAIQTLKEVDWIA
                     AEDTRNTGLLLKHFDISTKQISFHEHNAKEKIPDLIGFLKAGQSIAQVSDAGLPSISD
                     PGHDLVKAAIEEEIAVVTVPGTSAGISALIASGLAPQPHIFYGFLPRKSGQQKQFFGS
                     KKDYPETQIFYESPHRVADTLENMLEVYGDRSVVLVRELTKIYEEYQRGTISELLESI
                     AETPLKGECLLIVEGASQDVEEKDEEDLFLEIQARIQQGMKKNQAIKEVAKIYQWNKS
                     QLYAAYHDWEEKQ"
     gene            complement(2393..2710)
                     /gene="yabA"
                     /locus_tag="VQU30_001489"
     CDS             complement(2393..2710)
                     /gene="yabA"
                     /locus_tag="VQU30_001489"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000358230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA replication initiation control protein YabA"
                     /protein_id="HET2447579.1"
                     /translation="MDKKELFDALDDFSQQLLVTLADVEAIKKNLKSLVEENTALRLE
                     NSKLRERLGEVEADAPVKAKHVRESVRRIYRDGFHVCNDFYGQRREQDEECMFCDELL
                     YRE"
     gene            complement(2750..3640)
                     /locus_tag="VQU30_001490"
     CDS             complement(2750..3640)
                     /locus_tag="VQU30_001490"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000806705.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit delta'"
                     /protein_id="HET2447580.1"
                     /translation="MKQDQLKAWQPAQFDRFVRILEQDQLNHAYLFSGFFGSLEMAQF
                     LAKSLFCTDKVGVLPCEKCRSCKLIEQEEFPDVTLIKPVNQVIKTERIRELVGQFSQA
                     GIESQQQVFIIEQADKMHPNAANSLLKVIEEPQSEVYIFFLTSDEEKMLPTIRSRTQI
                     FHFKKQEEKLILLLEQMGLVKKKATLLAKFSQSRAEAEKLANQASFWTLVDESERLLT
                     WLVAKKKESYLQVAKLANLADDKEKQDQVLRILEVLCGQDLLQVRVRVILQDLLEARK
                     MWQANVSFQNAMEYLVLKEI"
     gene            complement(3637..4275)
                     /locus_tag="VQU30_001491"
     CDS             complement(3637..4275)
                     /locus_tag="VQU30_001491"
                     /EC_number="2.7.4.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004261378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dTMP kinase"
                     /protein_id="HET2447581.1"
                     /translation="MSKGFLVSLEGPEGAGKTSVLEALLPILEEKGVKVLTTREPGGV
                     LIGEKIREVILDPSHTQMDAKTELLLYIASRRQHLVEKVLPALEAGKLVIMDRFIDSS
                     VAYQGFGRGLDIEAIDWLNQFATDGLKPDLTLYFDIEVEEGLARIAANSDREVNRLDL
                     EGLDLHKKVRQGYLSLLDKEGNRIVKIDASLPLEQVVETTKAVLFDGMGLAK"
     gene            complement(4495..5292)
                     /gene="proC"
                     /locus_tag="VQU30_001492"
     CDS             complement(4495..5292)
                     /gene="proC"
                     /locus_tag="VQU30_001492"
                     /EC_number="1.5.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004254731.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyrroline-5-carboxylate reductase"
                     /protein_id="HET2447582.1"
                     /translation="MKIGFIGLGNMGASLTKSVLQARPSDEILLANRSQVKVDAFIAN
                     FGGQTSNNEEIFEEADVIFLGVKPAQFSELLSQYQTILEKRESLLLISMAAGLTLEKL
                     ASLIPSQHRIIRMMPNTPASIGQGVISYALSPNCRAEDSEIFCQLLAKAGLLVELGES
                     LINAATGLAGCGPAFVYLFIEALADAGVQTGLPRETALKMAAQTVVGAGQLVLESQQH
                     PGVLKDQVCSPGGSTIAGVASLEAHAFRGTVMEAVHQAYKRTQELGK"
     gene            complement(5296..6558)
                     /locus_tag="VQU30_001493"
     CDS             complement(5296..6558)
                     /locus_tag="VQU30_001493"
                     /EC_number="1.2.1.41"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate-5-semialdehyde dehydrogenase"
                     /protein_id="HET2447583.1"
                     /translation="MVSRQEQFEQVQAVKKSINTASEEVKNQALLAMADHLVAATEEI
                     LAANALDMAAAKGKISDVMLDRLYLDADRIEAMARGIREVVALPDPIGEVLETSQLEN
                     GLVITKKRVAMGVIGIIYESRPNVTSDAAALTLKSGNAVVLRSGKDAYQTTHAIVTAL
                     KKGLETTTIHPNVIQLVEDTSRESSYAMMKAKGYLDLLIPRGGAGLINAVVENAIVPV
                     IETGTGIVHVYVDKDADEDKALSIINNAKTSRPSVCNAMEVLLVHENKAVSFLPRLEQ
                     VLVADRKEAGLEPIQFRLDSKASQFVSGQAAQAQDFDTEFLDYILAVKVVSSLEEAVA
                     HIESHSTHHSDAIVTENAEAAAYFTDQVDSAAVYVNASTRFTDGGQFGLGCEMGISTQ
                     KLHARGPMGLKELTSYKYVVTGDGQIRE"
     gene            complement(6568..7698)
                     /locus_tag="VQU30_001494"
     CDS             complement(6568..7698)
                     /locus_tag="VQU30_001494"
                     /EC_number="2.7.2.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004240022.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate 5-kinase"
                     /protein_id="HET2447584.1"
                     /translation="MNNRSETMKYKRIVFKVGTSSLTNEDGSLSRSKVKDITQQLAML
                     HEAGHELILVSSGAIAAGFGALGFKKRPTKIADKQASAAVGQGLLLEEYTTNLLLRQI
                     VSAQILLTQDDFVDKRRYKNAHQALSVLLNRGAIPIINENDSVVIDELKVGDNDTLSA
                     QVAAMVQADLLVFLTDVDGLYTGNPNSDPRAKRLERIETINREIIDMAGGAGSSNGTG
                     GMLTKIKAATIATESGVPVYICSSLKSDSMVEAAEETEDGSYFVAQEKGLRTQKQWLA
                     FYAQSQGSIWVDKGAAEALSQHGKSLLLSGIVEAEGVFSYGDIVTVFDKESGKSLGKG
                     RVQFGASALEDMLRFQKAKGVLIYRDDWISITPEIQLLFTEF"
     gene            complement(7781..9661)
                     /gene="cbpE"
                     /locus_tag="VQU30_001495"
                     /gene_synonym="pce"
     CDS             complement(7781..9661)
                     /gene="cbpE"
                     /locus_tag="VQU30_001495"
                     /gene_synonym="pce"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000728269.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphorylcholine esterase CbpE"
                     /protein_id="HET2447585.1"
                     /translation="MKKKLTSLALVGAFLGLSWYGNVQAQESSGNKIHFINVQEGGSD
                     AIILESNGHFAMVDTGEDYDFPDGSDSRYPWREGIETSYKHVLTDRVFRRLKELGVQK
                     LDFILVTHTHSDHIGNVDELLSTYPVDRVYLKKYSDSRITNSERLWDNLYGYDKVLQT
                     AAEKGVSVIQNITQGDAHFQFGDMDIQLYNYENETDSSGELKKIWDDNSNSLISVVKV
                     NGKKIYLGGDLDNVHGAEDKYGPLIGKVDLMKFNHHHDTNKSNTKDFIKNLSPSLIVQ
                     TSDSLPWKNGVDSEYVNWLKERGIERINAASKDYDATVFDIRKDGFVNISTSYKPIPS
                     FQAGWHKSAYGNWWYQAPDSTGEYAVGWNEIEGEWYYFNQTGILLQNQWKKWNNHWFY
                     LTDSGASAKNWKKIDGIWYYFNKENQMEIGWVQDKEQWYYLDVDGSMKTGWLQYKGQW
                     YYFAPSGEMKTGWVKDKEAWYYMDSTGIMKTGEIEVAGHHYYLEESGAMKQGWLKKAN
                     DWYFYKTGGSRAIGWIKDKDKWYFLKENGQLLVNGKTPEGYTVDSSGAWLVDVPIEKS
                     ATIKTTSHSEIKESKEVVKKDLENKETSQHESVTNSSTSQDLTSSTSQSSETSVNKSE
                     SE"
     gene            complement(9664..10551)
                     /locus_tag="VQU30_001496"
     CDS             complement(9664..10551)
                     /locus_tag="VQU30_001496"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RluA family pseudouridine synthase"
                     /protein_id="HET2447586.1"
                     /translation="MEIKIETGGLRLDKALSDLSELSRSLANEQIKSGQVLVNGQVKK
                     AKYTVQEGDVVTYHVPEPEVLEYVAEDLPLEIVYQDEDVAVVNKPQGMVVHPSAGHTS
                     GTLVNALMYHIKDLSGINGVLRPGIVHRIDKDTSGLLMIAKNDDAHLVLAQELKDKKS
                     LRKYWAIVHGNLPNDRGVIEAPIGRSEKDRKKQAVTAKGKPAVTRFHVLERFGDYSLV
                     ELQLETGRTHQIRVHMAYIGHPVAGDEVYGPRKTLKGHGQFLHAKTLGFTHPRTGKTL
                     EFKADIPEIFKETLERLRK"
     gene            complement(10541..11002)
                     /locus_tag="VQU30_001497"
     CDS             complement(10541..11002)
                     /locus_tag="VQU30_001497"
                     /EC_number="3.4.23.36"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase II"
                     /protein_id="HET2447587.1"
                     /translation="MKKRAIVAVIVLLLIGLDQLVKSYIVQQIPLGEVRSWIPNFVSL
                     TYLQNRGAAFSILQDQQLLFAVITLVVVIGAIWYLHKHMEDSFWMFLGLTLIIAGGLG
                     NFIDRVSQGFVVDMFHLDFINFAIFNVADSYLTVGVIILLIAMLKEEINGN"
     gene            complement(10999..11907)
                     /locus_tag="VQU30_001498"
     CDS             complement(10999..11907)
                     /locus_tag="VQU30_001498"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001025716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HET2447588.1"
                     /translation="MNIQQLRYVVAIANSGTFREAAEKMYVSQPSLSISVRDLEKELG
                     FKIFRRTSSGTFLTRRGMEFYEKAQELVKGFDIFQNQYANPEEEKDEFSVASQHYDFL
                     PPTITAFSERYPDYKNFRIFESTTVQILDEVAQGHSEIGIIYLNNQNKKGIMQRVEKL
                     GLEVIELIPFHTHIYLCEGHPLAQKEELVMEDLADLPTVRFTQEKDEYLYYSENFVDT
                     SASSQMFNVTDRATLNGILERTDAYATGSGFLDSDSVNGITVIRLKDNLDNRMVYVKR
                     EEVELSQAGTLFVEVMQEYFDQKRKS"
     gene            11900..12097
                     /locus_tag="VQU30_001499"
     CDS             11900..12097
                     /locus_tag="VQU30_001499"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001842783.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HET2447589.1"
                     /translation="MFIFYPQLLYLFIIPYFRSFPKRKKEHPILLNYLHYLPFSRQSY
                     FQNQFKKISGYTPLQYRKEKR"
     gene            complement(12149..12820)
                     /locus_tag="VQU30_001500"
     CDS             complement(12149..12820)
                     /locus_tag="VQU30_001500"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000746014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HET2447590.1"
                     /translation="MKKRAIQILLALSLIFYKSTWFWRVFNHLAKPYLPASREFFQIL
                     LLMESGVLFLAVIYLLVFAGKKIFHFKWQLRYFIYLLLGYIISYMSDFLFSYFISLSS
                     NQISLNETVEMMGRQEFPYFLLIVCFIAPIAEELIYRGVLMTTFFKNSPWYGDVLLSA
                     IIFGYIHINFALTPLAFFIYASGGLILALLYRMTKNLYYPILVHILINITAFWDVWLL
                     LFSGS"
     gene            complement(12874..13095)
                     /locus_tag="VQU30_001501"
     CDS             complement(12874..13095)
                     /locus_tag="VQU30_001501"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000602450.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SP_0924 family bacteriocin-like peptide"
                     /protein_id="HET2447591.1"
                     /translation="MILMTKNINLTNEELELIQGGADSYGKNPNGRYDWEIEPVLTLP
                     VHGFCPRGTYDLGYIGGGNHLCKGSAARF"
     gene            13367..14176
                     /locus_tag="VQU30_001502"
     CDS             13367..14176
                     /locus_tag="VQU30_001502"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000593565.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HET2447592.1"
                     /translation="MIKLLALDMDGTLLNEAKEIPQAHITAIHKAIEKGVKLVLCTGR
                     PLFGVLPYYKKLGLDLQNEYVIVNNGCSTHQTSDWGLVDWQELSPADIEYLYDLAEKS
                     DVQLTLFDESHYFVLGGKPNQVIENDAKLVFSDLTEISLEEATSGKFRMFQGMFLGTK
                     EQTDDFEQRFAEELCQRFSGVRSQPVIYEAMPLGTTKATALSRLAEILKIDSSEIMAM
                     GDANNDIEMLQFAGLGIAMGNASDYVKSLADAVTSSNEEDGVARAIEKYIL"
     gene            complement(14357..15232)
                     /gene="aguB"
                     /locus_tag="VQU30_001503"
     CDS             complement(14357..15232)
                     /gene="aguB"
                     /locus_tag="VQU30_001503"
                     /EC_number="3.5.1.53"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001246759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-carbamoylputrescine amidase"
                     /protein_id="HET2447593.1"
                     /translation="MRNVRVATIQMQCAKDVATNIQTAERLVRQAAEQGAQIILLPEL
                     FEHPYFCQERQYDYYQYAQSVAENTAIQHFKLLAKELQVVLPISFYEKDGNVLYNSIA
                     VIDADGEVLGVYRKTHIPDDHYYQEKFYFTPGNTGFKVWNTRYAKIGIGICWDQWFPE
                     TARCLALNGAELLFYPTAIGSEPILDTDSCGHWQRTMQGHAAANIVPVIAANRYGLEE
                     VTPSEENGGQSSSLDFYGSSFMTDETGAILERAERQEEAVLLATYNLDKGASERLNWG
                     LFRDRRPEMYRQITD"
     gene            complement(15242..16327)
                     /gene="aguA"
                     /locus_tag="VQU30_001504"
     CDS             complement(15242..16327)
                     /gene="aguA"
                     /locus_tag="VQU30_001504"
                     /EC_number="3.5.3.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397151.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="agmatine deiminase"
                     /protein_id="HET2447594.1"
                     /translation="MMDSPKKLGYHMPAEYEPHHGTLMIWPTRPGSWPFQGKAAKRAF
                     TQIIETIAEGERVYLLVEQAYLSEAQSYLGDKVVYLDIPTNDAWARDTGPTILVNDKG
                     KKLAVDWAFNAWGGTYDGLYQDYEEDDQVASRFAEALERPVYDAKPFVLEGGAIHSDG
                     QGTILVTESCLLSPGRNPNLTKEEIENTLLESLGAEKVIWLPYGIYQDETNEHVDNVV
                     AFVGPAEVVLAWTDDENDPQYAMSKADLELLEQETDAKGCHFTIHKLPIPAVRQVVTE
                     EDLPGYIYEEGEEERYAGERLAASYVNFYIANKAVLVPQFEDVNDQVALDILSKCFPD
                     RKVVGIPARDILLGGGNIHCITQQIPE"
     gene            complement(16324..17451)
                     /gene="nspC"
                     /locus_tag="VQU30_001505"
     CDS             complement(16324..17451)
                     /gene="nspC"
                     /locus_tag="VQU30_001505"
                     /EC_number="4.1.1.96"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864914.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carboxynorspermidine decarboxylase"
                     /protein_id="HET2447595.1"
                     /translation="MKLEQVPTPAYVIDLAKLEANCRILQYVQEEAGCKVLLAQKAYS
                     LYKTYPLISQYLSGTTASGLYEAKLAREEFPGEVHVFAPAFKDEDMEELLGITDHIVF
                     NSERQLRKHGARCREAGVSVGLRLNPQCSTQGDHALYDPCAPGSRFGVTIDKIPSDLL
                     DLVDGLHFHTLCEQGADDLQTTLKAVEEQFGPYLHEVKWLNMGGGHHITREGYDVDLL
                     ISEIKRIRKTYNLEIYIEPGEAIALNAGYLATEVLDIVENGMEILVLDASATCHMPDV
                     LEMPYRPPLRNGFESQEKAHTYRLSSNTCLTGDVIGDYSFENPVQIGDRLYFQDMAIY
                     SFVKNNTFNGIGLPSLYLMDEQGDCSLLKAFGYQDFKGRLS"
     gene            complement(17451..18710)
                     /locus_tag="VQU30_001506"
     CDS             complement(17451..18710)
                     /locus_tag="VQU30_001506"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000088792.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="saccharopine dehydrogenase family protein"
                     /protein_id="HET2447596.1"
                     /translation="MSRLLVIGCGGVAQVAISKICQDSETFTEIMIASRTKSKCDDLK
                     AKLEGKTSTKIETAALDADKVEEVIALIESYKPEAVLNVALPYQDLTIMDACLATGVH
                     YIDTANYEAEDTEDPEWRAIYEKRCKELGFTAYFDYSWQWAYQEKFKEAGLTALLGSG
                     FDPGVTSVFSAYALKHYFDEIHYIDILDCNGGDHGYPFATNFNPEINLREVSAPGSYW
                     EDGKWVEVEAMSIKREYDFPQVGQKDMYLLHHEEIESLAKNIPGVKRIRFFMTFGQSY
                     LTHMKCLENVGLLRTDTINFNGQEIVPIQFLKALLPDPASLGPRTVGKTNIGCIFTGV
                     KDGVEKTIYIYNVCDHQECYAEVGSQAISYTTGVPAMIGTKLVMNGTWKQAGVYNLEE
                     LDPDPFMEALNEYGLPWVVVENPQMLD"
     gene            complement(18707..19567)
                     /gene="speE"
                     /locus_tag="VQU30_001507"
     CDS             complement(18707..19567)
                     /gene="speE"
                     /locus_tag="VQU30_001507"
                     /EC_number="2.5.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyamine aminopropyltransferase"
                     /protein_id="HET2447597.1"
                     /translation="MDLWFSEVHTPDVKLSLRTAKQLYAGKSEWQDIEVLDTPAFGKI
                     LILNGHVLFSDADDFVYNEMTVHVPMAVHPNPKKVLVIGGGDGGVAQVLTLYPELEQI
                     DIVEPDEMLVEVCREYFPDFAAGLDDPRVTIYYQNGLRFLRNCEYDYDIIINDATDPF
                     GHTEGLFTKEFYGNSYRALKEDGIMIYQHGSPFFDEDESACRSMHRKVNQAFPISRVY
                     QAHIPTSPAGYWLFGFASKKYHPVKDFDKEGWKKRQLFTEYYTANLHVGAFMLPKYVE
                     DILEEEEGKK"
     gene            19823..20104
                     /locus_tag="VQU30_001508"
                     /pseudo
     CDS             19823..20104
                     /locus_tag="VQU30_001508"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019770457.1"
                     /note="frameshifted; incomplete; missing C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
BASE COUNT         5835 a         4618 c         3572 g         6079 t
ORIGIN      
        1 tggtattatc aatcatgaac taggattcta gttttgcagg aagtctaatg taattctcaa
       61 gctgtgagtt cattatgatt tgtaaatccg atatatcttc agcagctaaa aacacatttt
      121 gaaatgttcc aagtccgttt tcaccaaaac tatattctct cttactatac ttactcttat
      181 tattctctat atagttagag tcaaggttct taacctcttg aagttcattt tctttacttc
      241 tgaggttaaa atcttttact tctgaagtta agttttttga cttctgtaag tcattttctt
      301 ttacctgaaa tatactcata aagtctttaa cataaatgat gttcggctta ccaagtccaa
      361 gccttactct ttcgatcagt cctattcctt tttttacatc aagctcatct aatgttttta
      421 tggcagttgg ctttgagata tttcttcttt tcataatttc ttcgacagta aaatagataa
      481 atactctgcc ttccttgtct atccagttat tcttaaatga cattcctgtc tgtttaagaa
      541 gtatggaata aaggataatt gcttctgctg ataagccccg aaattcttct ctatcaacta
      601 atatctccgg tacttttaag aagttaaatc tttccgcttc tctgttataa aaatattcaa
      661 agtccatgca agatcacctc ccttcttaaa aatttgcaaa gaaaaagacg atagtttttc
      721 ttctatcgcc tttggtaacc atttttatga aattttttaa agttaaaaat ataatttata
      781 atactatctt cttccatttt ctgattttag ttctgaaagt tccaaaaggt gcaaccgtat
      841 ttacatgaat aaacttatac acttcccaag tcgctgtttt agtcgcttca tcagcccact
      901 ttctcatatg cggttcaaat aattcttcct cactcaacga atcaatcatt gcagagatag
      961 aattaatatt ttcatttaat tttgctttca actcttgcag agataaatga gcgtaggtat
     1021 ctgtgaacca ctgatataat tcaccaagtt gattccattt aaatttatcc gatggtgttt
     1081 ttacttgaag cccctttctt tcatcttctt cccatttaag aaccaagttg gtccaaccaa
     1141 cctgataagc aaggttttct gctggagttc tgtcaacttc atcagctctc ttatctttta
     1201 aattttctgg aatattatca aattctaaaa tatatttctc aaatgttttc tctatctcag
     1261 cttttagttc ttctttattt tcgtatgttc gcaaaaaatc accttctttc tgatttatca
     1321 atcctttgat ttaaaatgac cttatttttc tatttatacc ttctaagaac gctataactg
     1381 ctgctccaaa catcggtatt ccgtatgggc ttaataaaaa acttaatacc aaagcttcta
     1441 taccaagtga tacatcttta tattatcatc actaattaag ttaaacagaa acagacagaa
     1501 ttattacatc ctgtctccct ttattgtttt tcttcccaat cgtggtaggc agcgtagagt
     1561 tgactcttat tccactggta aatcttagct acttccttaa tagcttgatt tttcttcatg
     1621 ccttgctgga tacgggcttg gatttctaag aacaagtcct cctcgtcttt ttcctccaca
     1681 tcctgactgg caccttcaac aataagaagg cattcgccct tgagtggcgt ttcagcgatg
     1741 ctttccagta attcagaaat tgtacctcgt tggtattctt catagatttt ggtcaattcc
     1801 ctgaccaaaa caaccgagcg gtcaccgtag acttctaaca tattttccaa cgtgtctgct
     1861 acacgatgag gtgattcata aaaaatctgt gtttcaggat aatctttttt agagccaaaa
     1921 aattgcttct gttgacctga ttttctcggt aaaaaaccgt aaaagatatg tggctgtggc
     1981 gctaaaccac tggcaatcaa ggcagaaatt cctgcagagg tacctggaac agtcacaact
     2041 gcaatttctt cctcaatagc tgccttaact aaatcatgac cagggtctga aatgctaggc
     2101 aaaccggcat cagagacctg agcaatactt tgccctgctt tcaagaaacc aatcaaatca
     2161 ggaatttttt ccttggcatt gtgctcatga aaactgatct gcttggtgga aatgtcaaaa
     2221 tgcttgagca aaagccctgt attgcgcgta tcctcagcag caatccagtc cacttctttc
     2281 aaggtctgga tagcacgaaa agtcatatca tctagattgc caatcggcgt tgccactaga
     2341 tacagcttgc catagggaga ctgcccctta aaactttttt gaatttgcat gcttactccc
     2401 tgtataacaa ctcatcacag aacatacatt cttcgtcctg ctctcgacgt tgtccataaa
     2461 aatcattaca tacgtgaaat ccatcacggt aaatacgacg gacactttcg cgaacatgct
     2521 tggccttgac gggagcgtct gcttccacct cacccaagcg ttctcgcaac ttactatttt
     2581 ccaagcgaag agctgtattt tcttctacca agctcttgag atttttcttg atggcttcca
     2641 catcggctaa agttaccaat aattgttggg aaaaatcatc cagcgcgtca aataattctt
     2701 ttttgtccat aaaacagccc tttcctttct ttatcattca tttttgagtt tatatttctt
     2761 tcaagaccag atattccatg gcattttgaa agctgacatt agcttgccac atttttctag
     2821 cttctagtaa atcttgtaga atcactctta ctcttacctg caagaggtcc tgcccacaga
     2881 gaacttcaag aatccgtaaa acctgatcct gtttttcctt atcatctgcc aagttggcta
     2941 atttggcaac ctgtagataa ctttcttttt tcttagctac taaccaagtc agcaggcgtt
     3001 cactttcatc gaccaaggtc caaaaacttg cctgattagc caacttttct gcttcagctc
     3061 gcgattgact aaacttagct aaaagagtcg cttttttctt aacaagtccc atttgttcta
     3121 agagtaagat aagtttttct tcttgctttt taaagtggaa gatctgagtc cgacttcgga
     3181 ttgtcggtaa catcttttcc tcatcgctag tcaagaagaa aatataaact tcactctggg
     3241 gttcttcgat gaccttgagc agagaattgg ctgcgttggg atgcatttta tccgcttgct
     3301 cgatgataaa gacctgttgc tggctttcaa tccctgcttg agaaaactgt cccaccaatt
     3361 cccgaatacg ttctgtcttg atgacctgat tgactggctt aatcaaggtg acatctggaa
     3421 actcttcctg ttcaatcagc ttgcaacttc ggcatttctc acatggtaag acgccaactt
     3481 tatccgtaca aaagaggctc ttagctaaaa attgcgccat ttccaagctt ccaaagaaac
     3541 ctgaaaagag ataggcgtga ttgagctggt cttgttctaa gatacggaca aaacggtcaa
     3601 actgagctgg ttgccaagcc tttagttgat cttgtttcat ttggccaagc ccattccgtc
     3661 aaacaagaca gccttggtag tttccacaac ttgctccaaa gggagactag catcaatctt
     3721 gacaatgcga tttccctctt tatccagaag agaaaggtag ccttgacgaa cttttttatg
     3781 caagtccaac ccttccaaat ccaaacgatt aacctcgcgg tcactattag cagcaatacg
     3841 agccagccct tcttccacct cgatgtcaaa atagagtgtc aaatcgggtt tgaggccatc
     3901 tgtcgcaaac tgattgagcc agtcaatggc ttcaatatct aagccacgac caaatccctg
     3961 ataggcaaca gaactatcga taaaacgatc catgatgacc aacttgccag cttcaagggc
     4021 tggaagaact ttttccacca aatgctgtct gcgactggca atatagagaa gtagctctgt
     4081 tttagcatcc atctgagtat gacttggatc caaaatcact tcccgaatct tctccccaat
     4141 caagactccg ccaggttcac gggtcgtcag cacctttact cctttttcct ctaaaattgg
     4201 tagcagagcc tctaaaacac tggtcttgcc tgctccctct ggtccctcaa gagagactaa
     4261 aaatcctttt gacatgtcta actcatttct tttttactac ttctattcta tcaaaaaaat
     4321 aggggtttgt gacaatcttt ttgtcttctc atttcatact caatgaaaat caaagagcaa
     4381 actaggaagc tagccgcagg ctgtacttga gtacggcaag gtgaagctga cgcagtttga
     4441 atttgatttt cgaagagtat cagccaccat aaaagaggca gataaaacta cctcttattt
     4501 acctagttct tgtgttcgtt tataggcttg atgaactgcc tccatgactg tgcctcgaaa
     4561 agcatgcgct tctaggcttg ctacgccagc aatagtcgaa ccgcctggac tacaaacttg
     4621 atctttcaaa actccaggat gttgctggct ttctaggacc aattgcccag ctcctaccac
     4681 agtttgggct gccattttca aggctgtttc tcgtggtaat cccgtctgaa cacctgcatc
     4741 tgccaaggcc tcaataaaga gatagacaaa ggctggtcca caacctgcaa gacctgtcgc
     4801 tgcattgatt aagctttctc ctaattcaac caagagacca gccttggcta aaagctgaca
     4861 aaagatctca ctgtcctcag ccctgcaatt aggagacaag gcataactaa tcactccttg
     4921 cccgatagaa gcaggggtat taggcatcat acgaataatt cggtgttggc ttgggataag
     4981 acttgctagt ttttctaagg tcaatccagc tgccatcgaa atcaaaagaa gactttctct
     5041 tttttcaagg atggtctggt attgagaaag cagttcagaa aactgagcag gcttaacacc
     5101 tagaaaaatc acatctgctt cttcgaatat ttcttcattg ttagaagtct gaccaccgaa
     5161 gttagcgatg aaagcatcca ccttgacttg actacgattg gcaaggagaa tctcatctga
     5221 cggtctagcc tgcaagacag acttggttaa actagcaccc atattcccca aaccgataaa
     5281 tccaatcttc atctcttact cccttatctg tccatcacca gtgaccacat acttgtagct
     5341 agtcaattcc ttcaagccca taggaccacg cgcgtgcaat ttctgagtag aaatccccat
     5401 ttcacaacca agaccaaatt gtcctccatc tgtgaaacga gttgaggcat taacatacac
     5461 cgctgcagag tccacttgat ctgtaaagta tgctgcagct tcagcatttt ccgtcacaat
     5521 ggcatccgaa tgatgggtac tgtgggattc aatatgcgca accgcttctt ctaaactgct
     5581 cacaacctta acagctagaa tatagtctaa aaactcggta tcaaagtctt gtgcttgagc
     5641 agcttgacct gaaacaaact ggcttgcttt gctatctagg cggaattgaa ttggttccaa
     5701 cccagcttct tttcgatctg caaccaacac ttgctccaag cgaggaagga agcttactgc
     5761 tttgttttca tgaaccagca gaacctccat ggcattacaa acagaaggac gactggtttt
     5821 agcattgttg atgatagaca gcgccttgtc ttcgtctgca tccttatcca catagacatg
     5881 gacaatccca gttcctgtct cgataacagg tacaatcgca ttctcaacca ctgcattgat
     5941 caagccagct cctccacgag gaatgagaag gtctagatag cccttggcct tcatcatagc
     6001 ataactactt tcacggctag tatcctccac cagttgaatc acatttggat gaatagtagt
     6061 cgtctccaag cccttcttca aggctgtgac aatggcatgg gttgtttgat aggcatcctt
     6121 accactacga agaacaaccg catttccact cttaagagtc aaagcagccg catcagacgt
     6181 cacatttgga cggctttcat agataatacc gatgacaccc atagctacac gtttttttgt
     6241 gataaccaaa ccattttcaa gctgacttgt ttctaaaact tcaccgattg gatctggtaa
     6301 ggcaaccact tcacgaattc ctcttgccat cgcttctata cgatctgcat ccaaataaag
     6361 acgatccaac atcacatctg agattttccc cttagccgct gccatatcga gggcattagc
     6421 cgctaaaatt tcctcagtag cagccactaa gtgatcagcc atggctagca aggcttggtt
     6481 tttcacttct tcactagctg tgttaatcga ttttttaaca gcctgtacct gttcaaattg
     6541 ttcttgtcta ctcaccatag tttacctcta aaattctgta aaaagtagtt ggatttcagg
     6601 agtaatggaa atccagtcgt cacggtaaat caagacaccc ttggcttttt gaaaacgcaa
     6661 catatcctcc aaagcagatg ctccaaattg cacgcgtcct tttccaagtg attttccact
     6721 ttccttatca aatactgtca cgatatcacc gtaagaaaag actccttctg cttcaacgat
     6781 accagataag agaagactct ttccatgttg agagagagct tccgcagccc ctttatcaac
     6841 ccaaatagaa ccttgactct gagcatagaa ggcaagccat tgtttctggg tacgaagccc
     6901 cttctcttga gcaacaaagt aagaaccatc ctcggtctcc tctgccgcct caaccatgga
     6961 atctgatttc aaggatgagc agatataaac aggaactcct gattccgtcg cgatagttgc
     7021 agccttgatt ttggttaaca tacccccagt tccgtttgac gaaccagctc caccagccat
     7081 atcaataatc tcacgattga tggtctcgat tctctccaag cgtttggctc ttggatctga
     7141 attaggattt ccagtataga gaccgtccac atctgtcaag aaaactaaaa ggtctgcttg
     7201 gaccatcgcc gctacttgag cacttagagt gtcattgtcc ccaaccttga gctcatcaat
     7261 aacgacacta tcattctcat tgatgatagg aattgcccca cggttgagca aaaccgacaa
     7321 agcctgatgg gcatttttat aacgacgctt atccacaaag tcatcttggg tcagcaagat
     7381 ttgtgcagaa acgatttgac gcaagagaag attggtcgta tattcttcca acaaaagtcc
     7441 ctgccctacc gctgctgaag cctgtttatc agcaatttta gtcggacgct ttttaaatcc
     7501 taaggctcca aaaccagccg caatggcacc tgaagacacc aaaatcaact catgaccagc
     7561 ctcgtgcagc atagccaact gctgggtaat atcctttacc ttactacgtg ataaacttcc
     7621 atcctcattt gtcagagaag aagtgcccac cttaaagaca atccgtttgt atttcatagt
     7681 ctcactccga ttattcatat ttatccatta taacatgaat aacaggaaat agaaaagagt
     7741 tgataggaaa aagaaggccc taaaaccttc ttttctacta ctattctgat tccgatttgt
     7801 ttacactcgt ttcagagctt tgtgaagttg aggatgtcaa atcttgacta gttgaagaat
     7861 ttgtaacact ttcatgttga ctcgtttctt tattttcaag atcctttttc actacttctt
     7921 tggattcttt tatttctgaa tgacttgtag ttttaattgt agcagatttc tcgatcggaa
     7981 catccactaa ccaggcacca cttgaatcca cagtatagcc ttctggtgtc ttaccattca
     8041 caagtaattg accattttct ttcaagaagt accatttatc cttgtcttta atccaaccta
     8101 tagctcgtga accacctgtc ttgtagaaat accaatcatt tgccttttta agccagcctt
     8161 gcttcatagc tcctgattct tctagatagt aatgatgtcc agcaacttct atctcacctg
     8221 tcttcatgat accagtagaa tccatatagt accaggcttc tttatctttt acccagcccg
     8281 ttttcatttc ccctgatgga gcaaagtaat accattgccc cttatattga agccaacctg
     8341 tcttcataga gccatcaaca tccaaataat accactgctc tttatcttga acccaaccaa
     8401 tttccatctg attttctttg ttaaaataat accagattcc atcaattttc ttccaatttt
     8461 tagcagaagc accagagtct gtcaaataga accaatgatt gttccatttt ttccattgat
     8521 tctgtaacaa gatacccgtt tggttaaagt aataccattc accttcgatt tcattccaac
     8581 cgacagcata ctctcctgta gaatcaggcg cttgatacca ccagttccca tatgcactct
     8641 tatgccaacc agcttgaaaa cttggaatcg gcttgtagga tgttgaaata ttgacaaaac
     8701 cgtcttttcg aatatcaaaa actgttgcat catagtcttt gctggctgcg ttgattctct
     8761 caattcctcg ttctttgagc caattaacat actcactatc aacaccattt ttccaaggta
     8821 gactatccga agtttgaaca atcaaactcg gactcaaatt tttaatgaaa tccttggtat
     8881 ttgatttgtt ggtatcatgg tgatgattaa acttcatcaa atcaactttt ccaatgagag
     8941 gaccatactt gtcttctgct ccatgaacat tatctaaatc gcccccaagg taaattttct
     9001 tgccattgac tttcaccacg ctaatcaagg aattggaatt gtcatcccaa attttcttta
     9061 attcacccga tgaatcagtt tcattttcat aattatagag ctgaatatcc atgtccccaa
     9121 actgaaaatg agcatcccct tgtgtgatat tttgaataac tgaaacacct ttttctgcag
     9181 cagtctgtaa aaccttatca tagccataca gattatccca tagacgttca gaattagtaa
     9241 tacgactatc actatatttc ttaagataga ctcggtcaac tggataggta gacagtaatt
     9301 catcaacatt tccaatatga tcactgtggg tatgggtcac caaaataaaa tcaagttttt
     9361 ggacacccaa ttccttcaaa cgacgaaaga cacggtctgt tagaacatgc ttataagacg
     9421 tttcaattcc ttctctccat ggataacgag aatcacttcc atctgggaaa tcataatctt
     9481 ctcctgtatc caccatggca aaatgtccat tgctttcaag aataatcgca tcactgccac
     9541 cttcttgaac attgataaag tggattttat ttcctgaact ttcttgagcc tgaacattcc
     9601 cataccatga caaacctaaa aaagcgccta caagtgctaa actagttaat ttctttttca
     9661 ttcttacttt ctcaatctct ccaaggtttc cttaaaaatc tctgggatat ctgctttaaa
     9721 ttccaaggtc ttacctgttc tcggatgagt aaaacctaaa gtcttggcat gaagaaattg
     9781 tccatgtcct ttcaaagtct tgcgaggacc atagacctca tcaccagcga ctggatggcc
     9841 gatataagcc atgtggacac ggatttgatg agtgcgccct gtctccagtt gcaactctac
     9901 taagctataa tcgccaaagc gttccaagac gtgaaaacgc gtcactgcag gcttcccttt
     9961 agcagttaca gcctgtttct tacggtcttt ttcactccgg ccaatcggcg cttcaattac
    10021 accacgatca ttaggcagat ttccatgaac aatcgcccaa tatttgcgga gagacttttt
    10081 atctttgagt tcttgggcaa gtactagatg cgcatcatcg tttttagcaa tcatgagaag
    10141 acctgacgta tccttatcaa tacggtgaac aatccctgga cgcagaaccc cattgatacc
    10201 cgacaagtcc ttaatatgat acatgagggc atttactagg gttccactgg tatgaccagc
    10261 actcgggtgc acaaccattc cctgaggttt gttaacgaca gccacatcct catcttggta
    10321 gactatttct agcggaagat cctcagccac atactctaat acctctggtt ctggcacatg
    10381 gtaagtgacg acatcaccct cttggactgt gtatttagct ttcttgactt gaccattgac
    10441 caagacctgg cctgatttaa tttgttcatt cgcgagacta cgtgataatt ctgacaaatc
    10501 tgacaaagcc ttatccaaac gcagaccacc agtttcaatt ttaatttcca tttatttcct
    10561 cttttagcat tgcaatcaat aaaataatca ctccaaccgt cagatagcta tctgccacat
    10621 tgaaaattgc aaagttgata aagtcaaggt ggaacatatc cacaacaaag ccctgactga
    10681 ccctgtcaat aaagtttcca agaccacccg cgattattag agtcaaaccc aagaacatcc
    10741 agaatgagtc ctccatgtgt ttatgtaaat accaaatggc acctatcacg acaaccagag
    10801 taatgacagc gaataacagc tgctgatctt gtaagataga aaaggctgca cctcgatttt
    10861 gcaggtaggt caagctaacg aaattgggaa tccaggagcg cacttcaccc agtggaatct
    10921 gctggacgat ataggatttg accaactgat ccagcccaat taaaagcagt acaatgactg
    10981 ccactattgc tctttttttc atgatttcct cttttgatca aaatattctt gcatgacttc
    11041 tacgaagaga gtcccagctt gactaagctc cacttcttca cgtttaacat agaccatgcg
    11101 gttatctagg ttatccttga gacgaataac tgtaatgcca ttaacactgt cactatctaa
    11161 aaatccagaa cctgtcgcat aggcgtccgt ccgctccaaa ataccattca aggtggcacg
    11221 gtctgtcaca ttaaacatct gtgagctagc gctggtatcg acaaagttct ctgaataata
    11281 aaggtactcg tctttctctt gagtgaaacg aaccgttggt aaatccgcta aatcctccat
    11341 gactaattcc tctttctggg ctaaaggatg accctcacag agataaatat gggtatggaa
    11401 aggaatcaat tcgatgacct ccagacctaa cttttcaacc cgttgcataa tccccttttt
    11461 attttgattg ttgaggtaga taatcccaat ctcactatgc ccttgcgcca cttcatctaa
    11521 tatttgaaca gtagttgatt caaaaatacg gaagttctta tagtcaggat agcgctctga
    11581 aaaggccgta atagttggtg gtaagaagtc atagtgctgg ctagcaacgg aaaattcatc
    11641 tttttcttct tcaggattgg catactgatt ttgaaaaata tcaaatcctt taaccaattc
    11701 ttgcgctttt tcataaaatt ccatcccacg acgggtcaag aaagtccctg agctggtccg
    11761 acggaaaatc ttaaagccca actctttttc caaatcacga acagaaatag acagactcgg
    11821 ctgactaaca tacatctttt cagcagcttc acgaaaagta ccactattgg caatagccac
    11881 aacatagcgt aattgttgaa tgttcatctt ctacccccaa cttctttatc ttttcattat
    11941 accatatttt agaagttttc caaaaaggaa aaaagaacat cctattcttc ttaactatct
    12001 tcactatctg cctttctcac gccaatctta ttttcaaaat caattcaaaa aaataagtgg
    12061 ctacacacca cttcagtatc ggaaagaaaa acgttgacta tttgtgaaaa aagaaaatgc
    12121 cggaaaattc cgacattttt ttagtaagct aacttcctga aaataggagt aaccaaacat
    12181 cccagaaggc agtgatattg atgagaatat gaactagtat tggatagtag agatttttag
    12241 tcatgcgata caatagagct aaaatcagac ctccactagc ataaatgaaa aaagcaagag
    12301 gagttaaagc aaaattgata tgaatataac cgaaaataat agcagaaagc aaaacatctc
    12361 cgtaccaagg tgagtttttg aaaaaggttg tcataagcac acctcgataa atcaattcct
    12421 cagcaatagg ggcgatgaag caaacgatga gcaagaaata agggaactcc tgtctcccca
    12481 tcatttctac cgtttcattc aaagaaatct gatttgaaga cagggatatg aaatacgaaa
    12541 agaggaagtc agacatatat gaaatgatgt agcccagtaa aaggtagatg aagtacctca
    12601 gctgccactt gaaatgaaaa attttctttc ctgcaaaaac cagtagatag atgaccgcta
    12661 agaaaagaac tccgctctcc atcaaaagca gaatctgaaa aaattcacga cttgctggta
    12721 gatagggctt tgcgaggtga ttgaaaactc tccaaaacca agttgatttg taaaaaatta
    12781 aggacaatgc tagtaaaatt tgaatagccc gttttttcat attaaattct ctgctttctc
    12841 cacttatttc ttcatattac taataaattt tacttaaaat ctcgcagcac ttcctttgca
    12901 aagatgattg cctcctccaa tatatcctaa atcataggtg cctctgggac aaaatccatg
    12961 aaccggcaga gttaatactg gttctatttc ccaatcgtac ctaccattag gatttttacc
    13021 atatgaatct gctccacctt gtatcagctc taattcttca tttgttagat ttatattttt
    13081 tgtcattaaa atcatgatat atttcctcca ttattcttca gattagttga gtaatctgat
    13141 actcatacct acttacaaaa aaactattat attaagttgg ttttttaatt tgtctagttg
    13201 caacattgac aaacatagta tagcatatct ttgcgaaata tcctcttcaa atcatgaatt
    13261 gtcatcaaaa catcttaaac tataaaatca attagtctca agctttctat caatttcttc
    13321 tccaaaatat gctataataa tagcaaaaga taaagaagga agacctatga ttaaactact
    13381 agccttggat atggacggca ccctcctcaa tgaagccaag gaaatcccac aagctcacat
    13441 tactgctatt cacaaagcca ttgaaaaagg tgtcaaactg gttctctgta cgggtcgccc
    13501 ccttttcggt gtcctcccct actacaaaaa actgggactc gacctccaga atgagtatgt
    13561 gattgttaac aacggttgtt caactcacca gactagcgac tggggcttgg ttgactggca
    13621 agaacttagt ccagctgaca tcgaatacct ctatgacctt gctgaaaaga gtgatgttca
    13681 gttgacactt tttgacgagt cacattattt tgttctcggt ggaaagccca atcaagttat
    13741 tgaaaatgat gctaaactag tattttcaga cctgactgaa atttctcttg aggaagcgac
    13801 tagtggaaag ttccggatgt tccaaggtat gtttttagga acaaaagaac aaacagacga
    13861 ttttgagcag cgttttgctg aagagctttg ccaacgattc agtggagttc gttcgcagcc
    13921 tgtcatttat gaagcaatgc cacttggaac gacaaaggct actgctcttt cacgactagc
    13981 tgagattttg aagattgatt cctcagagat tatggccatg ggcgatgcta ataacgatat
    14041 cgaaatgctc cagtttgcag ggcttgggat tgcaatggga aatgccagcg attatgtcaa
    14101 atctcttgcg gatgccgtta cctcaagcaa cgaagaagac ggcgttgcgc gtgctattga
    14161 gaaatatatt ctataaaaaa gaaaagcaaa tagacagaag ttactgctat ttgctttttt
    14221 gctaatattt taaaatacgg actaatcaat agagaagaat agcgaatcat aaaaatcgat
    14281 ttactagatg ccatagtatc ttatagttgc taataagaag ttagtctagc agaatgaatc
    14341 tctcatttct cccacactaa tctgtaattt gtctatacat ttctggtctt ctatctcgaa
    14401 acaagcccca gtttaggcgt tcacttgctc ccttgtctag gttataagta gctaacagaa
    14461 cagcttcttc ttgtctttca gctcgttcta gaatagctcc tgtttcatcc gtcataaagg
    14521 aggaaccgta gaagtcaaga ctggaactct gtccgccatt ttcctcacta ggagtaacct
    14581 cctctaaacc ataacgattg gctgcgatga ctggaacaat attcgctgct gcgtgccctt
    14641 gcatagtacg ttgccagtga ccacaactat ctgtatccaa aattggctct gaaccgatag
    14701 ctgtaggata aaagagcaat tcagcaccat tcaatgcaag acagcgcgct gtttcaggga
    14761 accattgatc ccaacagata ccgataccaa tcttagcata gcgagtattc cagaccttga
    14821 aaccagtgtt accaggcgtg aaatagaatt tttcttgata ataatggtca tctggtatat
    14881 gggtctttcg ataaacgccc agcacttccc catctgcatc aatgacggca atagagttat
    14941 acaagacatt accatctttt tcatagaaac tgattggtaa aacaacttgt agttccttag
    15001 caagcaactt aaaatgctga atggcagtat tttccgctac agattgggca tactggtagt
    15061 agtcatactg acgttcctga cagaaatagg gatgttcaaa caactcgggc aagagaataa
    15121 tttgggctcc ttgctcagca gcctgacgta ctaaacgctc tgcggtttgg atatttgttg
    15181 ccacatcctt agcgcattgc atctgaatgg ttgcaactct tacatttctc atctttttct
    15241 cctattctgg aatttgttgg gtgatacagt ggatattgcc accacctaag agaatatctc
    15301 tggctggtat tccgacaact ttacggtctg ggaaacactt gctgaggata tctaaggcca
    15361 cttggtcgtt tacatcctca aactgtggaa ccaagacagc cttgttggcg atataaaagt
    15421 ttacgtagga agctgctagt cgttcacctg cgtatcgctc ttcttctcct tcttcataga
    15481 tgtagcctgg caaatcttct tctgtcacaa cttgtcgaac tgcagggata ggcaatttat
    15541 gaatggtgaa gtgacaacct tttgcatctg tttcctgttc taagagttcg agatctgctt
    15601 ttgacatggc atactgggga tcattttcgt catctgtcca agccaaaaca acctcagcag
    15661 gaccaacaaa ggcaacaaca ttatcgacgt gttcattggt ttcatcctga taaataccat
    15721 aaggaagcca aataactttt tcagcaccaa gactttctaa taatgtgttt tcaatctcct
    15781 ctttagtcaa gttaggattg cgaccaggac taagcaagca actttcagtt acgagaatag
    15841 ttccttgacc atcgctatgg attgcgcctc cttccagtac aaaaggttta gcatcataga
    15901 caggcctttc caaggcctca gcaaaacgac tggctacttg gtcatcctct tcataatctt
    15961 gataaagacc atcataggtg cctccccaag cattaaaggc ccaatccacg gctaatttct
    16021 tacctttatc attgacgaga atggttgggc cagtatcacg cgcccaggca tcattggtgg
    16081 gaatgtctaa ataaacaacc ttgtctccaa gataggattg ggcttcagat agataggcct
    16141 gctccaccaa aagatagact ctttcccctt ctgctatggt ctcgatgatc tgagtaaatg
    16201 ctcttttagc agcctttcct tgaaaaggcc atgatcctgg tcgagtcggc catatcatga
    16261 gggtaccatg atggggttcg tactctgctg gcatgtgata gcctaatttt tttggactgt
    16321 ccatcatgat aatctccctt taaagtcttg atagccaaaa gctttgagta agctacagtc
    16381 tccctgttcg tccatgagat agagacttgg caatccaata ccattaaagg tattattttt
    16441 gacaaaagaa taaatggcca tgtcttgaaa ataaagtctg tctccgattt ggactggatt
    16501 ttcaaaacta taatcaccaa tcacatcgcc agtcagacag gtattagaag aaagtctgta
    16561 ggtatgggct ttttcctgtg actcaaagcc atttctcaaa ggtggacgat agggcatctc
    16621 aagtacatca ggcatatggc aggtcgcaga ggcgtctaaa accaagattt ccataccgtt
    16681 ttctacaata tctaatacct cagttgctaa ataacccgca ttaagcgcaa tggcttcacc
    16741 aggctcgata tagatttcaa gattgtaagt ttttcggata cgcttgattt ctgaaatcag
    16801 caaatccaca tcgtaacctt ctcttgtaat atgatgacca ccacccatat tgagccattt
    16861 tacctcatgt aagtagggac caaactgttc ttctactgct ttcaaagttg tttgtaaatc
    16921 atctgctccc tgctcgcaaa gggtatgaaa atgaagtccg tcaaccaaat ctagcaaatc
    16981 gctcggaatc ttgtctatag taactccaaa gcgagaacca ggtgcacaag ggtcatagag
    17041 cgcgtgatct ccttgagttg aacactgagg gttgaggcgc aaaccaacac tgacaccagc
    17101 ctctcgacaa cgagccccat gcttacgcaa ctgtctctct gagttaaaga cgatatggtc
    17161 tgttatccca agcaattcct ccatgtcctc atccttgaaa gctggtgcaa aaacatggac
    17221 ttcaccagga aattcttccc ttgccaattt ggcctcatag agtccactag ctgtcgtacc
    17281 tgatagatac tggctaatca agggataagt tttgtagagg gaatatgcct tctgggcaag
    17341 caagaccttg caaccggcct cttcttgtac atattgtaga atgcggcaat tagcttctaa
    17401 cttggccaag tcaataacat aggctggtgt tggtacttgt tctaacttca ttagtccaac
    17461 atttgtggat tttcaaccac aacccatggc aaaccatact cattcaaagc ttccatgaat
    17521 ggatctggat ctaactcctc aaggttatac actccagctt gtttccaagt tccgttcatg
    17581 actaattttg tcccaatcat ggctggaacg cctgtcgtgt atgaaattgc ttgtgacccg
    17641 acttctgcat agcactcttg atggtcgcaa acattgtaga tgtagatagt cttttcaacg
    17701 ccatctttga cacctgtaaa gatacatcca atattggttt tacctacagt acgtggacca
    17761 aggctagcag gatctggaag caaggctttc aaaaattgaa ttggaacaat ttcttggccg
    17821 ttaaagttaa tggtatccgt acgaaggagt ccaacatttt caagacattt catgtgcgtc
    17881 aagtaagatt gaccaaaagt cataaagaaa cgaatgcgtt tgacacctgg aatgttcttg
    17941 gccaatgatt cgatttcttc atggtgaagg agatacatat ctttttgtcc aacttgaggg
    18001 aaatcatact cacgcttgat agacatagct tcgacttcga cccatttccc atcttcccag
    18061 taagaacctg gcgcagaaac ctcacggaga ttaatttctg gattaaagtt ggttgcaaat
    18121 ggataaccgt ggtcaccgcc attacagtct aaaatgtcga tataatggat ttcatcaaaa
    18181 tagtgtttga gggcataagc tgaaaagaca ctagttacac ctgggtcaaa accagaacca
    18241 agaagagcag tcaagcctgc ttctttgaat ttctcttgat aagcccactg ccatgagtag
    18301 tcaaagtagg ctgtaaaacc aagttcctta caacgttttt cgtagatagc acgccactca
    18361 gggtcttctg tgtcttctgc ttcgtagttg gctgtatcga tatagtgaac acctgttgcc
    18421 aaacaagcat ccataatggt taaatcttga taaggcagag ctacattcaa aacagcttct
    18481 ggtttgtagc tttcaatcag agcaatcact tcttcaacct tgtcagcatc aagagcagct
    18541 gtctcaatct ttgtacttgt tttgccttcc agtttagctt tcaagtcatc gcattttgac
    18601 ttggtacggc tagcaatcat aatctctgta aatgtttcgc tatcttgaca aatctttgaa
    18661 atagcaactt gggcaacgcc cccacaacca ataactagta aacgactcat ttttttcctt
    18721 cctcttcttc taaaatgtcc tcaacatact tgggcaacat aaaggctccc acgtgtaagt
    18781 ttgcagtgta gtattctgtg aaaagctggc gttttttcca gccttccttg tcaaaatctt
    18841 tgacagggtg gtattttttc gatgcaaatc caaacaacca atagccagct gggctagttg
    18901 gaatatgggc ctgataaacc cgactgattg gaaaggcttg attgaccttg cggtgcatgc
    18961 ttcggcaggc cgactcatcc tcgtcaaaga acggactccc atgctggtaa atcatgatgc
    19021 cgtcttcctt cagagctcga taactattgc cgtagaattc cttggtaaag agtccttccg
    19081 tatggccaaa tggatctgtc gcatcgttga tgataatatc atagtcatat tcgcagtttc
    19141 gcaaaaagcg tagcccattt tggtagtaaa tggtaacacg aggatcatct aggcctgcag
    19201 caaagtctgg gaaatactca cgacagacct cgaccaacat ctcatccggt tccacgatat
    19261 cgatttgttc cagttcagga tagagtgtta atacttgggc aacaccgccg tcaccacccc
    19321 caataaccaa tactttcttt ggatttgggt ggacagccat gggaacgtga acggtcattt
    19381 cattgtagac gaaatcatcc gcatctgaga acaagacatg gccatttaaa atcagtattt
    19441 tcccaaaagc tggcgtatcc aagacttcga tatcctgcca ttcacttttt ccagcgtaaa
    19501 gttgcttggc tgttctcaga gacaatttga catctggagt atgaacttca gaaaaccata
    19561 aatccatcta tttctcctta tattatattt agcgcagtta gctactgcca aagcccaagt
    19621 ggtatacttg gaataagcca ctgtggatta gttcatttcc tccaatcgct tgacgatttc
    19681 cgaaagggtc taaccacagc tttttgtttc aattggtaat gagtttgata acgcatagac
    19741 gttttatctc gtctaaggta acaaggcaaa aagttcgtgg ataaccaagt agacttgaaa
    19801 tactatatct ggaggtactc ccatgcttta tgtgggcatt gatgtcgcta aaaataaaca
    19861 cgatgttaca gccttgaatg ttcgaggaaa actgttctta aaccactcac tttttcaaat
    19921 aataaagctg gttttgaact cttagatctg tctcttcgac aactcaacca agactgtctc
    19981 atcgctcttg aaaataccgg acattatgcc tttaatctac tgaacttcct gcatgaacaa
    20041 ggatataaag tttacaccta cactcctttg ctcatcaagg aatttgccaa atcattatca
    20101 cttc
//
LOCUS       DAVBBO010000043        19766 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ST1
            SAMEA2066453-rid20184263.denovo.043, whole genome shotgun sequence.
ACCESSION   DAVBBO010000043 DAVBBO010000000
VERSION     DAVBBO010000043.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2066453
            Sequence Read Archive: ERR351777
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 19766)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 19766)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980402.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980402.1
            Genome Coverage       :: 176x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:17:33
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,141
            CDSs (total)                      :: 2,104
            Genes (coding)                    :: 1,953
            CDSs (with protein)               :: 1,953
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 16S)
            partial rRNAs                     :: 1 (23S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 151
            CDSs (without protein)            :: 151
            Pseudo Genes (ambiguous residues) :: 0 of 151
            Pseudo Genes (frameshifted)       :: 73 of 151
            Pseudo Genes (incomplete)         :: 76 of 151
            Pseudo Genes (internal stop)      :: 40 of 151
            Pseudo Genes (multiple problems)  :: 32 of 151
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..19766
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2066453-rid20184263.denovo.043"
                     /strain="ST1"
                     /db_xref="taxon:1313"
     gene            complement(481..1206)
                     /locus_tag="VQU30_001509"
     CDS             complement(481..1206)
                     /locus_tag="VQU30_001509"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000771194.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2447598.1"
                     /translation="MKLLKNELIKSKIFLFIIVDICIQILVILAIKTYILDISAPYSE
                     LDYNKYWYVLHALIYMPMIFPIQILYQNLREALIEDNNNGWNIMVINTNNLVKIIYIK
                     VTINIVRCFICYFVYTIFSLIQLGGMGTDMLLTNIIFPNIIFPNIMSFLLFLPIAIFM
                     QICCIRFDSILAKALPNILLILIVLITFQSDWNIFIPATYYYTEIQSTTNLGIKLLVC
                     IWIMGFEFSLLPKLIKLKEQNLV"
     gene            complement(1219..1956)
                     /locus_tag="VQU30_001510"
     CDS             complement(1219..1956)
                     /locus_tag="VQU30_001510"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397757.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HET2447599.1"
                     /translation="MIKLEFLKQKKSILWFVLIFPIILNALLYIDLTFRYRGYLLVHQ
                     NELALSNWQLIFKEQTIFYFSELFYLVLSLIIYEVFAVEFKNDAWLTVISLPFRNKYT
                     INSKLLITVVYTFTFWLSDYISLYVIGKAIDNSLEIGLIFFLKTFTIQLISSLMIMLL
                     YFLTLVLIRKISGIIPIGIIMMILTISIYYNDYNFKIYLPFTYLSHAFRVTESQFYMI
                     LLSNIIIIVLFYILIRKLNERSFEMKL"
     gene            complement(1949..2677)
                     /locus_tag="VQU30_001511"
     CDS             complement(1949..2677)
                     /locus_tag="VQU30_001511"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001018875.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HET2447600.1"
                     /translation="MAIVEIINLTKSFKDIEVIHNTSFYLNKGKVYGFVGPNGAGKTT
                     IIKMILGILKPDSGKITIFNQTVEQNSKNILSRIGLVLGPSFYGHLDAYKNLKLIANM
                     KGLSLDTERLNEYLSMVGLKDVKKKKVKNFSMGMKQRLSIAASLLGSPEILIWDEPIN
                     GLDPQGVIEIRSLIRFLQEKKGITFLISSHILSELDKVISDIIIINYGKVEFFGSCHY
                     LLQKYNCRNLEEAYLACLAGGEYD"
     gene            complement(2711..2881)
                     /locus_tag="VQU30_001512"
     CDS             complement(2711..2881)
                     /locus_tag="VQU30_001512"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000711941.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2447601.1"
                     /translation="MKKVNEYVISTAASLGVMIGIVFAIFLDFPVEYGISLGLLNGIV
                     LGSLIVYKNNKN"
     gene            complement(2924..5017)
                     /locus_tag="VQU30_001513"
                     /pseudo
     CDS             complement(2924..5017)
                     /locus_tag="VQU30_001513"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397758.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase domain-containing ABC transporter"
     gene            complement(5010..5558)
                     /locus_tag="VQU30_001514"
                     /pseudo
     CDS             complement(5010..5558)
                     /locus_tag="VQU30_001514"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000059560.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(5639..5701)
                     /locus_tag="VQU30_001515"
     CDS             complement(5639..5701)
                     /locus_tag="VQU30_001515"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_128650800.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SHP2/SHP3 family peptide pheromone"
                     /protein_id="HET2447602.1"
                     /translation="MKKISKFLPILVLVMDIIII"
     gene            complement(5870..6858)
                     /locus_tag="VQU30_001516"
                     /pseudo
     CDS             complement(5870..6858)
                     /locus_tag="VQU30_001516"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003050775.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing N-terminus and C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="relaxase/mobilization nuclease domain-containing
                     protein"
     gene            complement(6807..7934)
                     /locus_tag="VQU30_001517"
                     /pseudo
     CDS             complement(6807..7934)
                     /locus_tag="VQU30_001517"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000423473.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="alpha amylase N-terminal ig-like
                     domain-containing protein"
     gene            complement(8097..8981)
                     /locus_tag="VQU30_001518"
     CDS             complement(8097..8981)
                     /locus_tag="VQU30_001518"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000710121.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase family lipid kinase"
                     /protein_id="HET2447603.1"
                     /translation="MKKAMVIINPTSGGEKALDYKEKLENKAKEYFEYVETKITEKAL
                     DATHFAEEASREQYDAVVVFGGDGTVNEVISGIDERDYIPKLGIIPGGTGNLITKLLE
                     INQDIDGAIDELDFDLTNKIDIGKANDNYFGYIFSIGSLPEAIHNVEIEDKTKFGILT
                     YAVNTMKSVMTDQVFNIKVETENGNYVGEASHVLVLLTNYFADKKIFEENKDGYANIL
                     ILKDASIFSKLSVIPDLLKGDVVANDNIEYIKARNIKISSDSELESDVDGDKSDNLPV
                     EIKVLAQRVEVFSKPKED"
     gene            complement(9093..9947)
                     /locus_tag="VQU30_001519"
     CDS             complement(9093..9947)
                     /locus_tag="VQU30_001519"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000900021.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ADP-ribosylglycohydrolase family protein"
                     /protein_id="HET2447604.1"
                     /translation="MLGAIIGDIVGSVYEWNNIKTKDFPLFRKDCFFTDDTVMTCAVA
                     EAIMNGGQKDDFIDAMKKYGRMYPNADYGARFNAWLNSDNREPYNSFGNGSAMRISPC
                     AWIMDCGFYAKTGIWPSSRGLTSLSAEVTHNHPEGVKGAMATADAIFLCRFYFGGYCR
                     EYEQSINDNLTECKRRIKDYIEKEYDYNLSQTLDEIRPNYRFNETCQETVPQAIIAFL
                     ESRDFEDAIRNAISLGGDSDTLAAITCNIAEAAYGIPDWIKDKAYSYLDEPLKDVVRR
                     WENRIKAY"
     gene            complement(10005..10763)
                     /locus_tag="VQU30_001520"
     CDS             complement(10005..10763)
                     /locus_tag="VQU30_001520"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000262024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-grasp domain-containing protein"
                     /protein_id="HET2447605.1"
                     /translation="MVVYIRQSKLPSEVSINKYNAQVGAYLQGEEVILYQSFSEIKEL
                     TSEDIVVDYIMETRALLKMMGLNVPVYDYPIELKEFYGRKIYAGILGEIVNIPDNWGK
                     FIKPKAGSKVFTGRVVNGTHDLIGIGLPFDYPIWISEVVEFIAEWRCFVLDGRVLDVR
                     PYTGDYHAQFDASVIDEAISCWKDAPIAYGLDIGVTRDGRTLVVEVNDGYALGNYALS
                     PLKSINFHRARWKEMVKPYFEKNEIFKIQQDVVF"
     gene            complement(10825..11013)
                     /locus_tag="VQU30_001521"
     CDS             complement(10825..11013)
                     /locus_tag="VQU30_001521"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000179767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CopG family transcriptional regulator"
                     /protein_id="HET2447606.1"
                     /translation="MATDKNRIMISLDDKNLEKLENLVEDARDRRGMRLTKSQVIELL
                     LNTVDYFDDIMGAIYSKK"
     gene            complement(11335..11901)
                     /locus_tag="VQU30_001522"
     CDS             complement(11335..11901)
                     /locus_tag="VQU30_001522"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2447607.1"
                     /translation="MVILELYQNDYSKDLVAFDSIEDGKAFVAQIPGYTLETEDGFEV
                     EYFNPKNIPDYMEIIFNGNIVPLSKFMFDPEENVNIIWKEISNLSLKNDRVIEGYSKI
                     DAYVVNNHEVKTYVETRETNYRKAKDFLESRGYEIDRSFFGSEDGEAILYRKKGIEVW
                     HFLCHLDPMFVEIEDVEGYVKEEVGEIQ"
     gene            complement(12169..13848)
                     /locus_tag="VQU30_001523"
     CDS             complement(12169..13848)
                     /locus_tag="VQU30_001523"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000031864.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HET2447608.1"
                     /translation="MSKEKIKVYLYTRVSTSIQIEGYSLEAQKSRMKAFAIYNDYEIV
                     GEYEDAGKSGKSIEGRIQFNRMMEDIKSGKDGVSFVLVFKLSRFARNAADVLSTLQIM
                     QDYGVNLICVEDGIDSSKDAGKLMISVLSAVAEIERENIRIQTMEGRIQKAREGKWNG
                     GFAPYGYKLEDGKLFINEEEAVAIRTIFDQYVNTTIGANGISKYLENHGIRKIPRQNG
                     KNPLFDAGLIRKILKNPVYNGKIAFGRRTLEKVHGTRNEYKQVEQDEYLISEGIHEAI
                     VSDEVWQAAQVKLKSQAKKYEHVNKGKDTRTHLLSGIVKCPICGVGMFGNKCIKKKKD
                     GTKYKDFYYYGCNHRQMIRGHKCTFSKQIREELLDDAVAEVIVKIVSNPKFASMMQEK
                     INMKVDTSEIEKEIDNYQKELRKSHSTKFKLIEEIDNLDVEDKHYKRRKQDLDDRLYR
                     MYDKVDELESSLIDAKAKKQTIEAEKLTGDNIYKVLIYFDKLYKVMNDVERRQLISAL
                     ISEIQVYEEKQSNGQWLKSITFKLPIIEENLNIGLDNDEQVECVSLLEKRS"
     gene            complement(13940..14101)
                     /locus_tag="VQU30_001524"
     CDS             complement(13940..14101)
                     /locus_tag="VQU30_001524"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005761276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2447609.1"
                     /translation="MDNDWNGLADLIANLIAKYAGALDLDNLPDPTPAKNQEMKNSFD
                     MAKTQIETD"
     gene            complement(14785..15099)
                     /locus_tag="VQU30_001525"
     CDS             complement(14785..15099)
                     /locus_tag="VQU30_001525"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001835032.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2447610.1"
                     /translation="MGITWKDIEIDKEREGEIDKKSTPIFYGEFKNVRLSKEEYKNLK
                     EKLNSHTDIMINKLSRYMESSGKTYQNHYVTILKWYEEDKDKLRQKGLNKKMNYDVGE
                     SL"
     gene            complement(15065..15454)
                     /locus_tag="VQU30_001526"
     CDS             complement(15065..15454)
                     /locus_tag="VQU30_001526"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000690676.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HET2447611.1"
                     /translation="MPKRYLLDGKTPRISATNIDNGILGYYEDIDDKNYRVFENFISV
                     SFLGAVFYHKYKASLDMKIHCLKLKNKELNKEVAFYLTSIIRQALKNTEYKDQISSTV
                     LPDIKIKLPIDSRGTPDWNYMERYRDR"
     gene            complement(15842..16636)
                     /locus_tag="VQU30_001527"
     CDS             complement(15842..16636)
                     /locus_tag="VQU30_001527"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000677523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET2447612.1"
                     /translation="MKGLWSNNLTCGYDEKIILENINIKIPEEKISVIIGSNGCGKST
                     LIKTLSRLIKPLEGEVLLDNKSINSYKEKDLAKHIAILPQSPIIPESITVADLVSRGR
                     FPYRKPFKSLGKDDLEIINRSMVKANVEDLANNLVEELSGGQRQRVWIALALAQDTSI
                     LLLDEPTTYLDISYQIELLDLLTDLNQKYKTTICMILHDINLTARYADYLFAIKEGKL
                     VAEGKPEDILNDKLVKDIFNLEAKIIRDPISNSPLMIPIGKHHVSS"
     gene            complement(16636..17643)
                     /locus_tag="VQU30_001528"
     CDS             complement(16636..17643)
                     /locus_tag="VQU30_001528"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001180354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron ABC transporter permease"
                     /protein_id="HET2447613.1"
                     /translation="MQNLIIGIQKRKNRITLFSSLFLLIIISLSFFILLIGDESYSFS
                     TLIKVLNSETVPGASFSIMEIRLPKLLAGIIAGWSFGLAGFIFQTMLRNPLASPDIIG
                     VTSSSSIAAVFCILVLKTNSLTTGIISITCGLTSSLILFLLAKKDGFSAARLIILGIG
                     FQAVTRAGTSFLLLKVARYELQEVMRWLSGSLSFTKLDDIPLVLIVSIIATILVLFFN
                     KRLEIIELGEEIAIGLGANPELSRLVLIFCAVSLTAFSTSITGPIACISFLAGPIALN
                     IGKKRSPILAGLVGILLVLLSDIFSQNILPARYPVGVVTGLLGSPYLIYLLIKMNRRN
                     I"
     gene            complement(17643..18650)
                     /locus_tag="VQU30_001529"
     CDS             complement(17643..18650)
                     /locus_tag="VQU30_001529"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001244688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron ABC transporter permease"
                     /protein_id="HET2447614.1"
                     /translation="MRNKKQINLGIIFVICLGLLITIFLSLKLGTKEINIRDFLATFG
                     MGNTNDDFIKSIIYKRIPRTIFAILAGSSLAISGVLMQSVTRNPIADPGILGINTGAS
                     LSVVIGLSFLGISSSISHISFAIIGGLVSAIFVYAIAVSGKAGLTPIKLALSGTCVSM
                     ALSSFVSFLILPNNNVLDKFRFWQIGSLGAATLSSISTLLPFIILGHLIAIFISSDLN
                     ALAMGDEMAVGLGVNVNRIRSLAIIASVLLCSSITAIGGPIGFVGLIVPHFCGLFISK
                     DIRTMTISSSFIGAELLLICDIIGRMLGKPGEIEVGIITAIIGGPVLIYVTMKNRGVN
                     N"
     gene            complement(18640..19665)
                     /locus_tag="VQU30_001530"
     CDS             complement(18640..19665)
                     /locus_tag="VQU30_001530"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000790748.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-siderophore ABC transporter
                     substrate-binding protein"
                     /protein_id="HET2447615.1"
                     /translation="MKNKFFLIAILAMCIVFSACSSNSVKNEENTSKEHAPDKIVLDH
                     AFGQTILDKKPERVATIAWGNHDVALALGIVPVGFSKANYGVSADKGVLPWTEEKIKE
                     LNGKANLFDDLDGLNFEAISNSKPDVILAGYSGITKEDYDTLSKIAPVAAYKSKPWQT
                     LWRDMIKIDSKALGMEKEGDELIKNTEARISKELEKHPEIKGKIKGKKVLFTMINAAD
                     TSKFWIYTSKDPRANYLTDLGLVFPESLKEFESEDSFAKEISAEEANKINDADVIITY
                     GDDKTLEALQKDPLLGKINAIKNGAVAVISDNTPLAASCTPTPLSINYTIEEYLNLLG
                     NACKNAK"
BASE COUNT         6377 a         3631 c         2618 g         7140 t
ORIGIN      
        1 tggacatttt gaactaaaat taatttatta aacatatctc ataagcatat ctattatagg
       61 tgagacaata ttaagaaaga cggttaaaaa acaacctgac tccactggaa ttcaggaatc
      121 aggtcgctta agattttata ttattttact gtctacttga cagggagctg ttcaccaatg
      181 ggaatctata gctttttttg tgactgagaa ctattttatc tcagacttct tcaacacacc
      241 ttattattgg gcacttacgg aaggttaatg aattatttaa aataaaagta aagagaagca
      301 aacagacact ctatagctgt tagacgcttt ttagagtaat aacaatttga taaagtgaat
      361 acaacttgct taattaagcg taagaaacca gaatcataaa atcaattact ttgaagtcat
      421 gactcacgtt gtattgtttc attgttaatc gtattcaatt atttaatttt cgagcaacat
      481 ttaaactaga ttttgttctt tcaattttat tagttttgga agaagggaaa attcaaatcc
      541 cataatccag atacaaacta ataatttaat acctaagttt gtagttgact gaatttctgt
      601 ataataataa gttgcaggta taaatatatt ccaatcactc tgaaacgtga ttaaaacaat
      661 aagtatcagc aaaatattag gtaaggcctt tgctaaaatg gaatcaaatc ttatacagca
      721 aatttgcata aagatagcta taggtaaaaa taacagaaat gacattatat tgggaaatat
      781 tatattggga aatattatat tggttaataa catatcagtt cccataccac ctaattgaat
      841 taaagaaaaa attgtataaa caaaataaca aataaaacat ctcacgatat ttatcgttac
      901 ttttatatag atgattttca cgagattatt agtgttaatc accatgatat tccaaccatt
      961 attattatct tcaatcaatg cctctcttag attttgatac aaaatttgta taggaaaaat
     1021 cattggcata tatattaaag cgtgtaaaac ataccaatac ttattataat caagctctga
     1081 gtatggtgcc gaaatatcta aaatatatgt ttttatagct agaatgacta gaatctgaat
     1141 acagatgtca acaataataa ataaaaatat tttactctta atcaattcat ttttaagtaa
     1201 cttcattttt attacctatt aaagtttcat ctcaaaactt ctttcgttca atttacgaat
     1261 taatatataa aaaagtacga tgattattat attagatagt aaaatcatat aaaattgact
     1321 ttcagtcact ctaaaagcat gagaaagata agtaaatggt aagtaaatct taaaattata
     1381 atcgttgtag tatatgctaa ttgttaaaat catcattata ataccaattg gtattattcc
     1441 agaaattttc cttataagta ctaaagttag aaaatataat aacattatca tcaacgagga
     1501 aattaattga atggtaaatg tttttaaaaa gaaaatcaaa ccaatctcta aactgttatc
     1561 aatagccttc ccaataacgt ataagctaat ataatcagac aaccaaaaag taaatgtgta
     1621 aaccactgta atgagtaatt tagaatttat tgtgtacttg tttctaaatg gcaatgaaat
     1681 tacggttaac catgcatcat ttttaaattc tactgcaaac acttcgtaaa ttattaaaga
     1741 tagaactaaa taaaatagtt cagaaaaata aaatattgtt tgttctttaa aaattaactg
     1801 ccaattagat aaagcaagtt cattttgatg caccaataaa taacctcgat acctaaaagt
     1861 taagtctata tataacaaag cattcagaat tattggaaaa ataagaacaa accataagat
     1921 gctttttttc tgctttagaa actctaattt aatcatattc acctccagct aaacaagcta
     1981 agtaggcttc ttccagattt cgacaattat acttttgtaa aaggtagtgg caagaaccaa
     2041 aaaattcaac tttcccataa tttataatta taatatcaga tatcacttta tccagttcac
     2101 taagaatatg acttgatatt aaaaatgtaa tacctttttt ctcctgtaga aaacggatta
     2161 aacttctaat ttcaattaca ccctgtggat caagtccatt gattggttca tcccaaatta
     2221 atatttctgg actacctaac aatgatgcag ctatacttag acgttgtttc atgcccattg
     2281 aaaaattttt cacttttttc tttttaacat cttttaatcc taccattgat agatattcat
     2341 taagtctttc agtatctaaa ctaagccctt tcatatttgc tattaacttc aaatttttat
     2401 aagcatcaag atgaccataa aatgaaggtc ccaaaactaa tcctatccta gataatatat
     2461 ttttggaatt ctgttctacg gtttgattaa aaatagttat tttcccagaa tctggtttta
     2521 aaatccctag aatcattttg ataattgtag tttttccagc cccatttggt ccaacaaaac
     2581 catatacttt tcccttattt aaataaaatg aagtgttatg aataacttca atatctttaa
     2641 agctttttgt tagatttata atttcaacta tagccatctc tactccttag tttacagcaa
     2701 aaaattatgc ttaattctta ttgtttttgt aaacaatcag cgaacccaat actattccat
     2761 tcaacaaacc taaagaaata ccatattcaa ctggaaaatc taaaaaaatt gcaaatacta
     2821 ttccaatcat cacccctagt gaggctgctg ttgaaattac atattcattt actttcttca
     2881 ttttctttac acctcatttc ctttttgtat ataagctgta gtactatcca ccaagatcca
     2941 ttaagtactt atgatttcct gactcaacaa tcttaccacc tttcattaca aaaataatat
     3001 ccgcatcctt aatcgttgac aatctatgag ctataattat ttgagtacaa tcctgacttt
     3061 gtatatactt tgttattctt tcctcattaa tagtgtctaa tgcactagtt gcttcatcta
     3121 aaattacaat actaggatta tttattaatg cacgtgccag tgctatccgt tgcctttgcc
     3181 cacctgaaat atttgacccc atctctgaga tgatagtatt aaatttcatc ggcatagcca
     3241 tgatttcatc atagatttga actgctttac aaacttcctc tatcttttgt gaagtaactt
     3301 cgttctttaa agttatatta tcaagaatac ttcggttcaa taaaaatgaa tcctgtggaa
     3361 ctactcctaa attttgactt aatatttttt tatctatttg attaatattt acaccatcaa
     3421 ataaaatttt tcctgtatca atcttatata atcctgatag tatttttgat aacgtacttt
     3481 ttcctgaccc cgattgaccg actagtgcaa ttctctgtcc tggctcaata gtcaaattta
     3541 aattttctat tacaggagct gagtctttgg aataagagaa agataggtcc ttaatatcta
     3601 ttctaccttc taaagaacac tttttaagac cattttcaac attctcttca ttttcaagcc
     3661 agatatcatt tactctattt aagtatcctg ctgccaaaat atactacgta taagcattaa
     3721 atattgagat ttctgaacta aataaaattg atgccatcgt ttgaaatgcg acaacctcac
     3781 ccaataaaat ttttccattt aaaacattat caagtccaaa aatcaatata attataggag
     3841 cgaacaattg aaatacatta gtagctgaat tgtataaaat atgcacaata cttcgttttt
     3901 tatactttgt caatacgttt tttaaatact tagaccagtt ttcatatatt tcatcttcta
     3961 atcccgatat ttttattgaa gaaatagtat ttaatgcttc tgtttctact gagtaaatca
     4021 atgattgttc ttgtaattct ctattaaccg tatcatacat tatttttcta gtactaaaca
     4081 gaaacaaaaa attgattaaa ctcaatataa gagctataat tgataatgtt tttgaactaa
     4141 gaaacatata tattacaaca cttagaatag tcccgatatc tactactccc ccaacaactt
     4201 ggttagtaaa tagctcccta aaaccactaa gactagaaat tctgtataaa atatctcctt
     4261 ttgccctgag ttcaaaaaaa ctatatggta gtttaagcaa atgcttaaat gtaaaacttt
     4321 caatatctct actaaaaaat atattagaaa atagaattcc catactccta gccaagatag
     4381 aaataaggta caaacaaagt agagaaaata aaattaaaaa cgaggtttga aaagaaaatg
     4441 tattccctaa tgcagaatta ataaactttg aagtcattac tggtacggaa agtattatta
     4501 agtaacttat tattgaaaat agtaacgtca aaatcaatcg accttttacc tttgaaaaac
     4561 tagagaatac tcttatccat ggagaaggaa actgcgactt caaagattga taattttcgt
     4621 taggaaatga tagcagtact atattactaa aatgttttga aaactcctta aactcataat
     4681 ttatatatcc tttagaagga tccattatat agaccttatt cttttttact ttgtaaataa
     4741 ctacataatg ttgattatcc cagaatgcta ttaatggtaa cggaagttca ctaattttat
     4801 ttacatcttt aacttgatat gagccagtat caaaatttcg tttattcaat aactgtttca
     4861 agtcacctat actataacca tctctccctt tttctatatc acgtcttaaa tctagtaatg
     4921 tctctttgct tttatagaaa tgtagtatgg acaagcagca acataaacca cattctattt
     4981 gagacatttg ctcaatatta ggtacttttc tagtcatcat gtcctcttaa ctccagtaat
     5041 aaaacattaa gtaatctatc atcttgtttt cgagatattt catagacaac tccagatact
     5101 cctagcataa aagaaaatgt attcatagta ttcaaatccg tacttaattc tggtttgata
     5161 acctgagaaa cgacattatc aaaataaaaa tctatagatt cttttattaa taggttttct
     5221 tcatctttca atattgcatc aagacaactg atagtaccta cagaaccgtg acataaattc
     5281 aattctctta ttttttctac attagttaat acattttcaa ttattgataa atcattattc
     5341 ccaatattag ttttatcgaa aatttctttt ctagctaata aaatgcccgg agctccataa
     5401 caccaaaaat taggaaagga atcattatga tttcttcata tgtctttcca attttttaat
     5461 atattattga aacatttatc ttctttatat agtaattcct ctatacattt taatatatct
     5521 gtactaggat taatttcata ataatatgat aattacattg ctactccaga ataatcgtgt
     5581 gctaaacctg ttactgttat attatctaat tgtgaaatac aataattaat acactttttt
     5641 aaatgatgat aatatccatc accaaaacca aaatcggtaa aaattttgaa attttcttca
     5701 tacttggact tcctttccgt ttttatttat tgtacaataa ataaaaacgg atttaatttt
     5761 tgttgggaaa atgggaaatt atgaaatcaa aacttggcat cacacttaga aaagttcgta
     5821 aaggaaaaca aattagtcta tgctctgtag cagatgaaca tctttcaaaa tcacaaatat
     5881 ctcgttttga acgtggggag tcagagatat cttgtattcg actaatcaat attttagaca
     5941 aattacatat tactttgtag gggagttttt ggctatcgtt gctcaattgt ctgattaagg
     6001 tcctaccctt gatgaaacaa ttattatcca tgttttcttt attatagaca aagtaagaag
     6061 acgtttctcg aatgtagact ttatattttt tatgattttc ttcttccata atatccaatt
     6121 gatagttggg aatgaaaata agaccgctct gtttgacacc gaaagacacc ttgatataga
     6181 cgcccttatc aactagcttc tctatttggt tctctgcaag ttccacttca aattcacgaa
     6241 cggtatctca tttttcctta aatgtcttaa aggcttcctc aatctcttca gtggatactt
     6301 tatccttatc tcgttcttct tggaaagcat ggtactgttc ctgtaaattc tctaatcctt
     6361 ctgaagcaac gacttcctta tttttaaaat aatcttgaaa aaatttgaca tcatataatt
     6421 tcttatcact tattttttga tgacccaaac ttatcttttg attattttct tccaggataa
     6481 aagttacatt ttttgtttta agtcaatggt tagattcaat tcttttgctt ttgttattaa
     6541 atcttctaaa gaattgacac ggtttaacaa aaattctaaa cgactttcaa tctcttgctt
     6601 agcaaaatgc gttctaaaaa attcttcatc atatagatct cgtttgctga gttggcgccc
     6661 tcgaattggt tttatcatcg ttctatctgt catcaaaaaa cggctatgct tttgactaaa
     6721 atcaatctga acatgcaact gctttgcttt ctctaaaaaa tcatcaaacg atttagattg
     6781 ctgaagcaaa aaataaagac gttgtttcaa ttcaaattta tgactagatt ccttatattt
     6841 tttataatct cgaaaagatc aggattttta gctaaaactg ccttacgaaa atccttccag
     6901 aactgatggt caatctcatt agccacatcc aaacgccaag catcgatatt aaactcttca
     6961 atccaataag tcgcaacctt taaaagataa ttcttgacct ctggattggc tgtatttagc
     7021 ttaggcatat agtcctcgaa accaaaaaca tgatagggta agtctctctt attaactagc
     7081 ttttcagttg tcaatgggaa ttgttgaata tggaaccaat ccttataagc agactgttca
     7141 ccatttttga cgacattttt tcattgaaga gattgcgaac caatatgatt aaataccgca
     7201 tccagcatga ctttcatgcc acgatgatgc gcttgatcca ccagttcccg aaaggtctcc
     7261 ttgtctccaa aataacggtc aatttcaaag taatctgtcg tattgtactt gtgattactt
     7321 gtagattcaa agatgggaca aagatatagt ccagtaatac ccaagtcttg caagtaattc
     7381 atatgatcaa taatcccctg taaatcacca ccaaagaaat catcgctctt aggtgtgaca
     7441 gatgaatccc agtctaaagt cccttctggg tttaatagag cattgccatt ggcaaatctt
     7501 tcaggaaata tctgatacca taccgtattt gaaacccagt caggaacctt gcaggcatca
     7561 atctcatgaa gataaggcaa cttaaatcca ttcccaattg catgaagatt ttctagagaa
     7621 ttttccacac accctttatc gccatacaaa atattttgac cttctgtatc tctgagctca
     7681 aagagatact ggatacgtgc aaagtcaact gacacttcaa cctgccaatg gtcaaataag
     7741 gtaccagaag ttatcttgac catttctttt gtatcctgat aaaactcttc cataaagata
     7801 aaagggtccc catagtgcaa gttgatgctt tcaatgtccc ctttcttagt tcgaattcga
     7861 atatggagtt tcttatcctt ataaagatag gcatactccg actcaggcct atggtaaata
     7921 gcactcaatt ccatcaattt gtctcctaaa gtattcattc aaattttacg caaacgtttt
     7981 caaactcaat aaatccagta tactattttt gtaaactatt tgcaaggaat gtccgttgtt
     8041 aaaggaacta tcttttaaag tatacaaaaa gccttaaaaa aggctttctc tatatactaa
     8101 tcctctttcg gttttgaaaa tacttctact cgctgagcta ggactttgat ttctacaggt
     8161 aggttatctg atttatctcc gtcaacatct gactccaatt cactatctga agagatttta
     8221 atattacgcg ctttgatata ctcgatatta tcatttgcga caacatcccc ttttaataaa
     8281 tcaggaatga cggataattt ggagaatata gaggcatctt tcagaatcaa aatgttggca
     8341 tagccgtcct tgttttcttc aaagattttc ttatcagcga agtaatttgt caaaaggacc
     8401 aaaacatggc tagcttcacc aacataattt ccattttctg tctcaacctt aatgttaaag
     8461 acctgatctg tcatgacaga cttcatggta tttacagcat aggttaaaat accgaatttt
     8521 gttttgtcct ctatttcaac attgtgaatc gcctcaggca gagaaccgat actaaagata
     8581 taaccaaaat agttgtcatt tgctttaccg atatcaatct tattggttaa atcaaaatcc
     8641 agttcgtcaa ttgcgccatc gatgtcttga ttgatttcca aaagttttgt aatgaggtta
     8701 cccgtaccgc ctgggataat ccctaactta ggaatgtagt ctctctcatc aatacctgaa
     8761 atgacttcat tgacagttcc atctccacca aacacaacca ctgcatcata ctgctcacga
     8821 gaagcttctt cagcaaaatg tgttgcatcc agcgcttttt cggtaatttt ggtttcaaca
     8881 tattcaaagt attcttttgc tttattctcc agcttttctt tgtaatccaa agccttctcg
     8941 ccaccagaag tagggttgat aattaccatt gcttttttca ttgattttat ccttaatttt
     9001 aaacagaaat gtttacattt cgtcgtatgc aagtaaatgt aatcctatta tacaatgaaa
     9061 atacagaaaa gagaaatctg acgtactgga gattaatacg cttttattct attttcccat
     9121 cgcctaacta catcctttaa gggttcatcc aagtaagaat aggccttatc cttgatccaa
     9181 tcaggaatac cgtaagctgc ctctgctatg ttacaagtga ttgctgcgag agtatcactg
     9241 tcgccaccaa gtgagatggc atttcttatc gcatcttcga agtctctact ttcaagaaag
     9301 gcgataatgg cttgagggac agtttcctga catgtttcgt taaaacgata gttaggacgg
     9361 atttcatcta aagtttgaga tagattgtaa tcgtattctt tttctatata atccttaatt
     9421 cgtcttttac actctgtaag attgtcgtta attgattgct cgtactctct acaataacca
     9481 ccaaagtaaa aacgacatag aaagatagca tcagctgtag ccatagcgcc tttgacacct
     9541 tctggatgat tatgagttac ctctgcagaa agactcgtaa gtcctctaga tgatggccat
     9601 ataccagttt tcgcataaaa accacagtcc atgatccaag cacatggaga aatacgcata
     9661 gctgatccat tcccaaagct attataaggc tcacggttat cgctgtttag ccatgcatta
     9721 aaccgagcac cgtaatcagc attcggatac attctgccat atttcttcat cgcgtcaatg
     9781 aaatcgtctt tttgtccacc attcataatt gcttctgcaa cagcacaggt cataaccgtg
     9841 tcatctgtaa aaaagcagtc cttccgaaat aaaggaaagt cctttgtttt gatattgttc
     9901 cattcgtaaa cagaaccgac aatatctcca ataattgctc caagcatcag attcctcctt
     9961 gttcattttg atgcttttta tattggttat ataccatatt tattttagaa aacaacatcc
    10021 tgttggattt taaaaatttc atttttttca aaatagggtt ttaccatttc tttccaccta
    10081 gctctatgaa aattgattga ttttaaagga gatagggcat aatttcccaa tgcataacca
    10141 tcatttactt caacaacaag tgttctgcca tcgcgagtaa caccgatatc tagtccataa
    10201 gctattggcg catctttcca acatgatatc gcttcatcaa ttacacttgc atcaaattgt
    10261 gcatgataat cacctgtata gggtcgaaca tctaatacgc gaccatctaa cacaaaacaa
    10321 cgccattcag ctatgaattc tacaacctca ctaatccata taggatagtc gaaaggtaga
    10381 ccaataccta ttaaatcatg ggttccatta acaactcttc cagtaaagac ttttgaacca
    10441 gctttaggct taataaattt tccccaatta tcaggtatat tcacaatctc tcctaaaata
    10501 ccagcataaa tctttcgacc ataaaactct ttaagctcaa taggatagtc ataaaccgga
    10561 acgtttaagc ccatcatttt tagtaatgct ctagtctcca ttatataatc tacaactata
    10621 tcttcacttg ttaactcttt tatttcagaa aaagattgat ataaaataac ttcttctcct
    10681 tgtaagtagg cacctacttg agcattgtat ttattaattg aaacctcact tggtaattta
    10741 ctttgtctaa tataaacaac catttcatca ctcctatatc actagtgtta cactgatttg
    10801 taaaaaataa tagcaatttt gctcttattt ttttgagtaa atagctccca taatatcatc
    10861 gaaataatca acggtattta ggagtaattc aataacctgg gactttgtta gtcgcattcc
    10921 ccttctatct ctagcatctt ctactaaatt ttcaagtttc tctagatttt tatcatccaa
    10981 gctaatcatt attctatttt tatcggttgc cattttcatc acctcaagtt aattctatca
    11041 caggtgtaac acttgtgtca actggctttt ataatacatt agtttaaaag tggagaggat
    11101 ttttaacaca gtaactttaa atctttggta ttaaaaaatt ttcacaatat ttatagaaat
    11161 aaaatctgtc tcaaatcagt tatcaaatct agtataaatt atgagcggct actctaatac
    11221 tttccctcta aacaagaaaa agacttacac tcaaggattt tcttcccccc cttcgttata
    11281 acgttttgac tcttttacta gcaaaggtat atactcacaa ggaactttgg ttgactattg
    11341 aatctctcca acttcttctt taacatatcc ttctacatct tcaatctcta caaacattgg
    11401 gtctaagtga cacaagaaat gccaaacttc gatccctttt tttctgtaaa gaatcgcttc
    11461 accgtcttca cttccgaaaa agcttctgtc gatttcatat ccgcggcttt ctaagaagtc
    11521 ttttgcttta cgatagttcg tttctcttgt ttcgacatag gttttaactt catggttgtt
    11581 aacgacatat gcatcaattt ttgaatatcc ttcgatcact ctatcatttt tgagggataa
    11641 atttgaaatc tctttccaaa taatgtttac attttcctca ggatcgaaca taaatttaga
    11701 taaaggaaca atatttccgt taaaaataat ttccatataa tccggtatgt ttttaggatt
    11761 aaaatactcc acttcaaaac catcttctgt ttccagagtg tatcccggga tttgagctac
    11821 aaaggctttc ccatcttcta tggaatcaaa tgctactaaa tctttagaat aatcattttg
    11881 gtacaattcc aatataacca tcgataatct ctccattttc attatcaggc taatgtaaat
    11941 aagcacgtca cctgaccaat tcaggctctc tgtatcatct catcatattt cctacttact
    12001 ttacgagtcc tatacccaga acacacctta tcgaccttcg gtctcacctc gttgcattgg
    12061 ctgaacatct acttttactt cgctgatgct tcaactcgta caagcagtga taccgcctca
    12121 gcgtgatgcg tcagtgggac tcaaaaggtt cggggaacct tttgaggatt aactacgttt
    12181 ctctaataaa cttacacatt caacttgttc atcattgtcc aaacctatgt tgagattttc
    12241 ttctataatt ggtagcttaa aagtaatgga ttttagccat tgtccgttag attgtttttc
    12301 ttcataaact tgaatttcag aaatcaaagc tgaaattaac tgcctacgct ctacatcatt
    12361 catgacttta tagagcttat caaaatagat cagaacctta tatatgttat ctcctgtaag
    12421 cttttcagct tcaatagtct gtttctttgc tttcgcatca attagtgatg attctaattc
    12481 atctactttg tcatacatac gatatagtct atcatctaaa tcctgtttcc ttctcttata
    12541 atgcttatct tcaacatcta aattatctat ttcctcaatt agcttaaact ttgtagaatg
    12601 actctttctc aattcctttt ggtaattatc tatttctttt tctatttcag aggtatccac
    12661 cttcatgttg attttttctt gcatcataga agcaaatttc ggattactta ctatcttgac
    12721 aatcacctct gcaacagcat catctaacaa ttcttctcta atttgcttac tgaatgtaca
    12781 cttatgacct cttatcatct gcctatggtt acaaccatag taataaaaat ctttatactt
    12841 tgtgccatct ttctttttct tgatacactt gttcccaaac attcccactc cacatatcgg
    12901 gcattttaca attccagaaa gcaagtgtgt gcgtgtatct tttcctttat tcacatgctc
    12961 atatttcttt gcttgagatt ttagcttaac ctgagcagct tgccaaactt catcggaaac
    13021 tatagcttca tgtatccctt cagatattag atattcatct tgttcaacct gcttatattc
    13081 atttcttgta ccatgaactt tttctaaagt tcttcttcca aatgctattt tcccattata
    13141 tacaggattc tttaatatct ttcttataag acctgcatca aacaaaggat tcttaccatt
    13201 ctgtcttggg atttttctaa ttccatgatt ctctaagtat ttagatatcc cattggctcc
    13261 tatcgtagta tttacatact ggtcgaaaat cgttcttatt gcaactgcct cttcctcatt
    13321 tataaacagc ttgccgtctt caagtttata tccatacgga gcaaagccac cattccattt
    13381 tccttccctt gctttttgaa tgcgaccttc cattgtttga atacggatgt tttctctttc
    13441 tatttcagcc acagctgata aaacagaaat cattagtttc ccagcatctt tagatgaatc
    13501 aatgccatct tcaacgcaga taagattaac tccataatcc tgcattatct gaagtgtaga
    13561 aagaacatca gcggcatttc ttgcaaatct tgataactta aacacaagaa caaaagatac
    13621 tccatctttt ccagatttta tatcttccat cattcgattg aactgtattc taccttcaat
    13681 agacttgcca gacttcccgg catcttcata ctctccaaca atttcataat cgttgtaaat
    13741 agcaaaagct ttcattcgtg atttttgtgc ctctaacgaa tacccctcta tctgtattga
    13801 cgtagatact cgtgtataga ggtatacttt tattttttct tttgacatag tattaatctc
    13861 aatataattt ttctatatca tatataattt ttttaattta agtttggact atcatttcaa
    13921 gtatattata acacttttat tagtccgtct caatttgtgt ttttgccatg tcaaaactat
    13981 ttttcatctc ttgatttttt gctggcgttg gatcgggtag attatctaaa tctaaagcac
    14041 cagcatattt tgcaatcaga tttgctatta aatcagccaa tccattccag tcattgtcca
    14101 atatatacct cctctaaagt tttatatcta ataattattt gtttaattaa gttttttgac
    14161 attgacaagt gctttggatt agcaacatag gaatctcacc tccgcctcta ttccggatga
    14221 gccggcttca accttagaag tatcattatc ctcattttct tcatagcgga tagggtatcc
    14281 ctccctatat tcaaactctt acttatcgct cactttcttt ttacttagca gaactttttt
    14341 tgccgaatta ttcagccgaa agatcttgac ggataggtta ttacgctcca aaaataatta
    14401 acgtcttgtc ttggtctatt caattgttaa ggttcaaaat ttatcgagag ttattaatct
    14461 ttttaaaatt tgaccatcag aaaatattta tcttaatgta acaaaattct ataaattacc
    14521 ctcttatact taacagtgaa aagaagtctt tcttggtaac caattttgaa atagaatttg
    14581 cttatataaa aaggtcaaat tcccactgca taagtagcag tgaaaattag accctcttgg
    14641 taactgtcat ctaaaagtct tctagcattt ctttaatttt ctaatcgcct ttaaagtgtc
    14701 atatttatat ttttttatct ctggcatact ttgatacctt tttagactta aagtctttaa
    14761 tagtgccttt ccacctcttt ttatctataa agattctcct acatcataat tcattttttt
    14821 atttaaacct ttctgtctta gtttgtcttt atcttcttca taccatttta agattgtcac
    14881 atagtggttt tgataggtct taccactgct ttccatgtat ctggatagtt tatttatcat
    14941 tatatctgtg tgtgagttta atttttcttt tagattttta tattcttctt tgcttaacct
    15001 tacatttttg aattctccat aaaaaatggg ggtggacttt ttatctatct ctccctctct
    15061 ctctttatct atctctatat ctttccatgt aattccaatc tggagtacct ctactgtcta
    15121 tcggtaattt aattttgata tctggcaata ctgtgctaga tatttgatct ttatattcag
    15181 tattttttaa agcttgccta ataattgaag ttaaatagaa tgctacttct ttattcaatt
    15241 ctttattttt taattttaaa caatgaattt tcatatctag gcttgcttta tatttatgat
    15301 aaaagactgc tcctaaaaat gaaacagata taaaattttc aaaaactcta taatttttat
    15361 catctatatc ttcgtagtaa cctaagatac cattgtcaat atttgtagca ctaattctag
    15421 gagtttttcc atcgagtaaa tatctttttg gaatagatga gcctgttggt acttgactcg
    15481 atttcccctt tttttcggta ataaatattt ctttttattt tgttgtctga tatttttcct
    15541 acctgtcctt tgtaggatga gtattttcta gattttcttg aataactttt tacttgaagt
    15601 tttagctttt gaactagtcg ttgtactttc tttttgttta ttatcagtcc tgatcttttt
    15661 aatattgctg ttattctcta tatcctattt ttcattcatg atattctttt actaatttta
    15721 tcttaaattc tgtgctgtat ttgccattaa aaaactgacc tcctttagtt agttttttgg
    15781 cctaactttt gagggtcagt tcaaaatttg cgacttttaa atgaattcca atattcaatt
    15841 attaagagct aacatggtgc ttgccaatag gaatcattag aggcgaattg gaaatagggt
    15901 cacgtataat ttttgcttca agattaaaga tatctttaac tagtttatca tttagtatat
    15961 cttcaggctt tccctctgca acaagtttac cttctttaat tgcaaatagg taatcagcgt
    16021 atcttgctgt tagatttata tcgtgcaaaa tcatgcaaat ggttgtctta tatttttggt
    16081 ttagatcagt caagaggtct aatagttcta tttgatatga gatatccaag taagtagttg
    16141 gctcatctaa aagtaggata cttgtatctt gggctagggc tagagctatc catactcttt
    16201 gcctttgacc cccagaaagt tcttcaacta ggttatttgc tagatcttca acattggcct
    16261 taaccattga tctgtttatt atttcaaggt catcttttcc aagactctta aaaggctttc
    16321 tgtaggggaa acgaccacgg cttacaagat cagctactgt tattgattca gggattattg
    16381 gagattgagg taatatagct atgtgttttg ctaaatcttt ttctttataa gaattaattg
    16441 atttattatc aagcaatact tctccctcta atggctttat aagtcgagac aaggttttaa
    16501 tgagtgttga tttcccacaa ccatttgacc caataataac tgatattttt tcttcaggta
    16561 tttttatatt tatattttcc aagattattt tttcatcata accgcaggta agattatttg
    16621 accacagacc tttcattata tattcctcct gttcattttt attagtaagt atattaagta
    16681 tggtgaacct aacaagccag ttacaacacc tactggatat ctagctggta aaatattttg
    16741 agagaatatg tctgataaca aaactagtaa aattccaacc aatccagcta atattgggct
    16801 tcttttcttg ccaatattta aggctatggg accagctaaa aaagatatac aagctattgg
    16861 tcctgtaatt gaagtagaaa aagcagttaa agatacagcg caaaaaatta aaacaagcct
    16921 tgaaagctcg ggatttgctc caagtccgat tgctatttct tcaccaagtt caataatttc
    16981 tagtctttta ttaaaaaata aaactaatat agtagcaata atacttacta ttagaacaag
    17041 aggtatgtca tctaactttg taaaagataa agagccactg agccatctca taacttcttg
    17101 taattcatat cttgctactt tcaacaataa aaatgaggtg cctgctcttg tgacagcttg
    17161 aaaaccaata cctaatatta tcagtcttgc tgctgaaaaa ccatcttttt tagctagtaa
    17221 aaataatatt aaagatgatg ttagtccaca agttattgaa ataattccag tagttaaact
    17281 atttgttttt aataccaata tgcaaaagac cgctgcaata gatgaagaac ttgtgacacc
    17341 gattatatca ggacttgcaa gaggatttct taacatagtt tgaaagataa atcctgccaa
    17401 tccaaaagac cagccagcta taattcctgc taataatttt ggtaatctaa tttccataat
    17461 cgaaaaacta gctccaggaa cagtttcact atttaagact ttaatcaaag ttgaaaaaga
    17521 ataactttca tctccgataa gtaaaatgaa aaatgataga ctgattatta ttaataaaaa
    17581 tagtgaggaa aatagtgtta ttctattttt tcttttttga atacctataa ttaaattttg
    17641 cattagttat taacccctct atttttcata gttacataaa taagtactgg acccccgatt
    17701 attgcagtaa ttatccctac ttcaatttca cctggtttac ctaacatacg gccgattata
    17761 tcacatataa gcaagagctc tgcacctata aaagatgaag aaatggtcat tgtgcgtata
    17821 tctttgctta taaataagcc acaaaagtga ggaactataa gacctacgaa gccaataggt
    17881 ccaccaattg cagtaatact tgaacataaa agcacacttg caattattgc aagtgatctt
    17941 atcctattaa cattaactcc aagaccaaca gccatttcat cacccatagc taaagcgttt
    18001 aaatctgatg aaataaatat agctatcaag tgacctaaaa ttataaaagg tagtagtgta
    18061 gatatagaag ataatgtagc tgctccaagg ctacctattt gccaaaatct aaatttgtct
    18121 aagacgttat tattcggtaa aattaaaaaa cttacaaaac tgcttaaagc catactaaca
    18181 caagttcctg ataaggctag ttttataggg gtaaggcctg cttttccgct tacagcaatc
    18241 gcgtatacaa aaattgcact tactaagcca ccaatgattg caaaacttat atggcttatg
    18301 cttgatgaaa ttcctaaaaa agaaagacca attactacac taagacttgc tcctgtgttt
    18361 ataccgagta tacctggatc agctattggg tttctagtaa ctgattgcat caatacaccg
    18421 cttatggcaa gactagaacc tgctaaaatt gcaaaaatag ttctaggtat tcttttatat
    18481 ataattgatt taataaaatc atcatttgta ttgcccattc caaaagttgc taaaaaatct
    18541 ctgatattaa tttcttttgt tccaagcttt aatgacaaaa atattgtaat aagaagacct
    18601 aggcagatta caaaaattat gcctaggttt atttgttttt tatttcgcat ttttgcatgc
    18661 atttcctaaa agatttaggt attcttcaat agtatagttt attgaaagtg gtgttggagt
    18721 gcatgaggct gctaacggtg tattatctga aattacagca acggcaccat ttttaattgc
    18781 atttatttta cctaaaagag gatctttttg taaagcttca agagttttat catcaccata
    18841 agttatgatt acatcagcat catttatctt atttgcttct tctgcagaaa tttcctttgc
    18901 aaaactatct tcactctcaa attcttttaa tgattcaggg aaaactagac ctaaatctgt
    18961 taaataattt gctcttggat ctttgctagt ataaatccag aattttgatg tatctgcagc
    19021 attaatcata gtaaataata ctttttttcc tttgattttt cctttgattt ctggatgttt
    19081 ttctaattct ttggatatac gagcttcagt atttttgatt aactcatcac cttctttttc
    19141 catacctaag gcttttgaat caattttaat catatctctc cataaagttt gccaaggttt
    19201 agatttgtat gctgctacag gagcaatttt tgatagagtg tcataatctt ctttagttat
    19261 accagaataa cctgctaaga taacatctgg tttagaattt gatattgctt caaagttaag
    19321 tccatccaaa tcgtcaaata ggttagcttt accatttagt tctttgattt tttcttctgt
    19381 ccatggtaaa actcctttat cagcacttac accgtaattt gcttttgaaa atccaacagg
    19441 aactattcct aaagctaatg ctacatcatg atttccccaa gcaatagttg caactctttc
    19501 aggtttttta tctaatatag tttgaccgaa agcatgatct aaaactattt tatcaggcgc
    19561 atgctcttta gaagtatttt cttcattttt aacagaatta gaagaacaag cgctaaaaac
    19621 tatacacata gctaaaatag ctattagaaa aaatttgttt ttcataaaaa ctccttaaac
    19681 atatttcaag tctattgtat cgataataat tatcattgtc aatagataca gttacaaatt
    19741 taataatata attttttcaa aaaagg
//
LOCUS       DAVBBO010000044        19051 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ST1
            SAMEA2066453-rid20184263.denovo.044, whole genome shotgun sequence.
ACCESSION   DAVBBO010000044 DAVBBO010000000
VERSION     DAVBBO010000044.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2066453
            Sequence Read Archive: ERR351777
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 19051)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 19051)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980402.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980402.1
            Genome Coverage       :: 176x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:17:33
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,141
            CDSs (total)                      :: 2,104
            Genes (coding)                    :: 1,953
            CDSs (with protein)               :: 1,953
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 16S)
            partial rRNAs                     :: 1 (23S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 151
            CDSs (without protein)            :: 151
            Pseudo Genes (ambiguous residues) :: 0 of 151
            Pseudo Genes (frameshifted)       :: 73 of 151
            Pseudo Genes (incomplete)         :: 76 of 151
            Pseudo Genes (internal stop)      :: 40 of 151
            Pseudo Genes (multiple problems)  :: 32 of 151
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..19051
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2066453-rid20184263.denovo.044"
                     /strain="ST1"
                     /db_xref="taxon:1313"
     gene            1..283
                     /locus_tag="VQU30_001531"
                     /pseudo
     CDS             1..283
                     /locus_tag="VQU30_001531"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="internal stop; incomplete; missing N-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=2
                     /transl_table=11
                     /product="transposase"
     gene            201..629
                     /locus_tag="VQU30_001532"
     CDS             201..629
                     /locus_tag="VQU30_001532"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001235657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HET2447616.1"
                     /translation="MSKSTSKRYYQVAIPFTRLFCLVLVSIDYINCLSETADKNWHKS
                     DRIFVTNTGKTVHSSILSKSLQRANERLKKPIPKHLSPHIFIHITISILSENKIPLKT
                     ITDRVGHPDSEVTNSIYTHVTKNMKDEAINVLDKVMKKIF"
     gene            complement(1121..1531)
                     /locus_tag="VQU30_001533"
     CDS             complement(1121..1531)
                     /locus_tag="VQU30_001533"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001124848.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2447617.1"
                     /translation="MPKKKIERISVIHREKILWLKWYFMRDKEKPKYSVLECKMFDAA
                     KNKDMLAYKKYATIKQITDIRVQTSEDDILTAIKEVYVYNHMNVIGACQRILFVSQSP
                     AYNKLNKWFETYSDLYFSIIPLPNMGAYHELVDS"
     gene            complement(1549..1926)
                     /locus_tag="VQU30_001534"
     CDS             complement(1549..1926)
                     /locus_tag="VQU30_001534"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001233892.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2447618.1"
                     /translation="MRKYLKEIKELQELKELLSSRNTPEVIIVEGNDDLGEFFQVDGE
                     LFSDIELLENLKKWREWEVQVIVDDWCNRGLNEYETGILYFPKHEDKMDYIRFNKGLE
                     PLYHALDEPYTTISKSEWLKLLD"
     gene            complement(1868..2296)
                     /locus_tag="VQU30_001535"
     CDS             complement(1868..2296)
                     /locus_tag="VQU30_001535"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000918209.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication protein"
                     /protein_id="HET2447619.1"
                     /translation="MAGNENDGLTSKQIKFIDAMLTEPTIDKACQKAGVSRATGHKYL
                     KVAAVKKTLRLKQDEMMDKTTQMLYLASSNAVSVLNDIMMDAKINPFIRTQAAKTILE
                     QSYKTHEIFGVVRQIEELRLEIEEVSKGDQRVTRTQGIIK"
     gene            complement(2340..2945)
                     /locus_tag="VQU30_001536"
     CDS             complement(2340..2945)
                     /locus_tag="VQU30_001536"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2447620.1"
                     /translation="MTFTTIKDDIKAFGKKKHGYMTGYIAKQEELHKQLQNGMIGEKY
                     AKDQLEAYKLEGDTYSRDTYNKIHAEIEKQHDLELEALKEKELSVTADDVAELTLLAS
                     MKMTKDELLGYFEKYKNKPLAIKKLWSIAEQYPEIAINLELFNAEQALESLILFFKRQ
                     LSYCHYSLLINGDKIQAVTTEMVVNSDAPELDRRLDEYLNK"
     gene            complement(3035..3208)
                     /locus_tag="VQU30_001537"
     CDS             complement(3035..3208)
                     /locus_tag="VQU30_001537"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2447621.1"
                     /translation="MTENKDNKLLEMMEKGFVLYSKNGIIKYIEIPDHGSIKLKAQDG
                     QLVYKEVTTGEQC"
     gene            complement(3807..4703)
                     /locus_tag="VQU30_001538"
     CDS             complement(3807..4703)
                     /locus_tag="VQU30_001538"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000838906.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HET2447622.1"
                     /translation="MKSLQSSLGNIETFKLDELCPKHEIQLTQIKGERHVVVGWNENG
                     EVIKEVRCIPPYCEQCQEEQKKQDEEDAIADNLNAKLYLQTYNVLMSNKSYVADEFKT
                     KTFDDFNAVTSEEKRFLEFAKGQVQKYLDGMRGNTLITGGTGIGKTLLSVAIAKGINE
                     GYKTKGEPKSVLFVSLTEMIKQIKEGWNYGKGATLTEFEATELMKSVDYLIIDDLGAK
                     NAVIKPKSDWEQDLLFDVLNNRENTIFNTNLDSDELKIVYNERNYSRILKGLEGNTFK
                     AFTIKDKRYSINQLKNKVKQLK"
     gene            complement(4715..5524)
                     /locus_tag="VQU30_001539"
     CDS             complement(4715..5524)
                     /locus_tag="VQU30_001539"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001140556.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DnaD domain protein"
                     /protein_id="HET2447623.1"
                     /translation="MAKTKVYFWLKIDKKFFDNIFIKRLKTVPGGYTMTVIYIRLMLE
                     SLESDCILYYEGYFNNLKEELALKLDVSEDDIDMTMAYFTKCGLIQIDEDKNAELPQA
                     KAMVMSETNWASYKREQRKKGKLEEVQPSLTFSNSCPTEIEKELEIEVDKEQSPTPST
                     INQDFVNLYKSFEAETGKALSPLQIQELQYMLEDFSPELIHEALKEAVSQGKANFAYI
                     KAILNRWKQDNLLTVELVRNSRAAREAKKQQTNQLEPTSYEDWIPTQEKPF"
     gene            complement(5599..5814)
                     /locus_tag="VQU30_001540"
     CDS             complement(5599..5814)
                     /locus_tag="VQU30_001540"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001003747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2447624.1"
                     /translation="MNELDISNTQAVFVTVILIGLLLYLNHRDRKKSAQLERENQQTI
                     ETPSEDLNPDYGRYIQLAGVDVWGRIE"
     gene            complement(5816..6016)
                     /locus_tag="VQU30_001541"
     CDS             complement(5816..6016)
                     /locus_tag="VQU30_001541"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000171238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2447625.1"
                     /translation="MTLDLDNMTQAEFDEAMAEIQLQSPNIFQLISDFVNKKVTSVEI
                     DDLLNMKRAEQVAYIKNYKARA"
     gene            complement(6013..6204)
                     /locus_tag="VQU30_001542"
                     /pseudo
     CDS             complement(6013..6204)
                     /locus_tag="VQU30_001542"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001841301.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(6193..6483)
                     /locus_tag="VQU30_001543"
                     /pseudo
     CDS             complement(6193..6483)
                     /locus_tag="VQU30_001543"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000424675.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="Rha family transcriptional regulator"
     gene            complement(6653..6805)
                     /locus_tag="VQU30_001544"
     CDS             complement(6653..6805)
                     /locus_tag="VQU30_001544"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000706985.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2447626.1"
                     /translation="MKIVTFKPTKQIDGGFYLPGIDILFVSDKADAKSTEDVILFISR
                     NGLNKS"
     gene            complement(6816..7082)
                     /locus_tag="VQU30_001545"
     CDS             complement(6816..7082)
                     /locus_tag="VQU30_001545"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015604664.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2447627.1"
                     /translation="MEILSKEIQLQGLQLLKQTLETLVELEKQRSSKLDLISRKELMD
                     LLGISATTLDNWEDLALKRYQTPMDGAKKVFYRLSDVYLFLAIK"
     gene            complement(7293..7475)
                     /locus_tag="VQU30_001546"
     CDS             complement(7293..7475)
                     /locus_tag="VQU30_001546"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012027461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HET2447628.1"
                     /translation="MLITLSLAEKVRIKRARLQLTKKAVSEQLGIKSQTLTKVENGNY
                     DASKRIYESVMTWLVE"
     gene            7537..8040
                     /locus_tag="VQU30_001547"
     CDS             7537..8040
                     /locus_tag="VQU30_001547"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844103.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HET2447629.1"
                     /translation="MYKMNRIKQLRKENNLTQRELANETKIPYRTIQRWENGETDIKS
                     DAAQVLADYFGVSIPHLLGYSDLIADTDSDIKAMAYSHLLTFVDEKQIKEFEKEFIRA
                     NDNSDTFGDLGSGEKALEKYYQALCYLVPPFRDILARYSFLSLDEKKSVYNIIVGLSN
                     NLSKENK"
     gene            8114..9277
                     /locus_tag="VQU30_001548"
     CDS             8114..9277
                     /locus_tag="VQU30_001548"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015604661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HET2447630.1"
                     /translation="MNIIEKIKKNGQRVYYASVYLGVDQLTGKKARTTVTATTKKGVK
                     VKARDAINTFAANGYTVKDKPTITTYNELVKVWWDSYKNTVKPNTRQSMDGLVRVHLL
                     PVFGDYKLSKLTTPILQQQVNKWADKANKGEKGAFANYSLLHNMNKRILKYGVAIQVI
                     QYNPANDVIVPRKQQKEKAAVKYLDNKELKQFLDYLDTLNQSNYENLFDVVLYKTLLA
                     TGCRISEALALEWSDIDLESGVISINKTLNRYQEINSPKSSAGYRDIPIDKATLLLLK
                     QYKNRQQIQSWKLGRSETVVFSVFTEKYAYACNLRKRLNKHFDAAGVTNVSFHGFRHT
                     HTTMMLYAQASPKDVQYRLGHSNLMITENTYWHTNQENAKKAVSNYETAISNL"
     gene            complement(9431..10735)
                     /gene="eno"
                     /locus_tag="VQU30_001549"
     CDS             complement(9431..10735)
                     /gene="eno"
                     /locus_tag="VQU30_001549"
                     /EC_number="4.2.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopyruvate hydratase"
                     /protein_id="HET2447631.1"
                     /translation="MSIITDVYAREVLDSRGNPTLEVEVYTESGAFGRGMVPSGASTG
                     EHEAVELRDGDKSRYGGLGTQKAVDNVNNIIAEAIIGYDVRDQQAIDRAMIALDGTPN
                     KGKLGANAILGVSIAVARAAADYLEIPLYSYLGGFNTKVLPTPMMNIINGGSHSDAPI
                     AFQEFMILPVGAPTFKEALRYGAEIFHALKKILKSRGLETAVGDEGGFAPRFEGTEDG
                     VETILAAIEAAGYVPGKDVFIGFDCASSEFYDKERKVYDYTKFEGEGAAVRTSAEQID
                     YLEELVNKYPIITIEDGMDENDWDGWKALTERLGKKVQLVGDDFFVTNTDYLARGIQE
                     GAANSILIKVNQIGTLTETFEAIEMAKEAGYTAVVSHRSGETEDSTIADIAVATNAGQ
                     IKTGSLSRTDRIAKYNQLLRIEDQLGEVAEYRGLKSFYNLKK"
     gene            10899..11345
                     /locus_tag="VQU30_001550"
     CDS             10899..11345
                     /locus_tag="VQU30_001550"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000131081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YueI family protein"
                     /protein_id="HET2447632.1"
                     /translation="MTDLSKQLLEKAHGGLKINPDEQRRYLGTFEERVLGYVDIDTAN
                     SPQLEKGFLFILENLQEKAEPLFVKISPTIEFDKQVFYLKEAKETDSQATIVSEEHIT
                     SPFGLVIHSNAPVQVEEKDLRLAFPKLWEVKKEEPAKTSLWKKWFS"
     gene            complement(11342..12457)
                     /locus_tag="VQU30_001551"
     CDS             complement(11342..12457)
                     /locus_tag="VQU30_001551"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000706318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerate kinase"
                     /protein_id="HET2447633.1"
                     /translation="MKIVIAPDSFKESLTAQQVAEAIKRGFQQSIADVECLLCPVGDG
                     GEGTVDAIRHSLDLKEKWIQVTDPFGQKEAMRYFQKGELALFEVADLVGLGKIPLEKR
                     NPLQIQTCGIGELILHLISKGIKDIYIDVGGTASNDGGLGIAAGLGYQFYDRDGNVLP
                     ASGQSLLNLASVSTENCYKIPEGVQIHILADVVSPLCGHQGATYTFGNQKGRHPTMFA
                     VVDQAIQDFYEKFSPATLEIKGAGAGGGLAGGLCAFAQASIVSGIDTCLDLINFDKKV
                     SDADLVVVGEGRLDSQSFAGKAPIGVAKRTPVGVPVIAICGSLAEDLPPLPFENIQAV
                     FSILEKSEPLEDSLKNASLYLERTAANIGHLLNMCKI"
     gene            complement(12466..12795)
                     /locus_tag="VQU30_001552"
     CDS             complement(12466..12795)
                     /locus_tag="VQU30_001552"
                     /inference="COORDINATES: protein motif:HMM:NF019887.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD hydrolase family protein"
                     /protein_id="HET2447634.1"
                     /translation="MERLAKSLGIAYFTANQLEVKEGLLTGKLVGQIISPQVKKETLE
                     KWRKKLKLSKERTVAIGDGGNNLLMLKSAELGIAFCSKEMLKKEIPHHVDKRDFLEVL
                     PLIDCLE"
     gene            complement(12749..13111)
                     /locus_tag="VQU30_001553"
     CDS             complement(12749..13111)
                     /locus_tag="VQU30_001553"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809343.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD-IB family phosphatase"
                     /protein_id="HET2447635.1"
                     /translation="MSQVKGLCVLDVDGTLILEEVIDLLGREAGHEAEISQITSRAMR
                     GELVFESSLRKRVSLLEGLPILVFDNVFNSIHLSLNVPEFISILQKNGILVGLVSGGF
                     TPIVGEISKIPWYCLFHC"
     gene            complement(13170..14603)
                     /gene="glgA"
                     /locus_tag="VQU30_001554"
     CDS             complement(13170..14603)
                     /gene="glgA"
                     /locus_tag="VQU30_001554"
                     /EC_number="2.4.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000697278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycogen synthase GlgA"
                     /protein_id="HET2447636.1"
                     /translation="MKILFVAAEGAPFSKTGGLGDVIGALPKSLVKAGHEVAVILPYY
                     DMVEAKFGNQIEDVLHFEVSVGWRRQYCGIKKTVLNGVTFYFIDNQYYFFRGHVYGDF
                     DDGERFAFFQLAAIEAMERIDFIPDLLHVHDYHTAMIPFLLKEKYRWIQAYEDIETVL
                     TIHNLEFQGQFSEGMLGDLFGVGFERYADGTLRWNNCLNWMKAGILYANRVSTVSPSY
                     AHEIMTSQFGCNLDQILKMESGKVSGIVNGIDADLYNPQTDALLDYHFNQEDLSGKAK
                     NKAKLQERVGLPVRADVPLVGIVSRLTRQKGFDVVVESLHHILQEDVQIVLLGTGDPA
                     FEGAFSWFAQIYPDKLSTNITFDVKLAQEIYAACDLFLMPSRFEPCGLSQMMAMRYGT
                     LPLVHEVGGLRDTVRAFNPIEGSGTGFSFDNLSPYWLNWTFQTALDLYRNHPDIWRNL
                     QKQAMESDFSWDTACKSYLDLYHSLVN"
     gene            complement(14600..15739)
                     /gene="glgD"
                     /locus_tag="VQU30_001555"
     CDS             complement(14600..15739)
                     /gene="glgD"
                     /locus_tag="VQU30_001555"
                     /EC_number="2.7.7.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260264.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-1-phosphate adenylyltransferase subunit
                     GlgD"
                     /protein_id="HET2447637.1"
                     /translation="MKIDKYSAILGNTVGFHNMSTLTDHRPVASLPFGGKYRLIDFPL
                     SSLANAGVRSVFGIFQQDNISSVFDHIRSGREWGLSTFLSHYYLGIYNTRVESSTVGK
                     EYYQQLLTYLKRSGSNQTVALNCDVLINIDLNQVFHLHSTTKEPITVVYKKLAKKDIS
                     EVNAILDVDETDHVLSHKLFDSKSTAETFNMSTDIFVVDTPWLIEHLEEEAKKEHPEK
                     LRYVLRDLAVKEGAFAYEYTGYLANIHSVKSYYQANIDMLESQKFYSLFSPNQKIYTK
                     VKNEEPTYYANTSKVRTSQFASGSIIEGQVANSVLSRNIHVHKDSLVKDSLLFPRVVI
                     GEGAQVEYAILDKGVEVEPGVVIRGTAEHPVVVKKGAKVTEDIHS"
     gene            complement(15729..16871)
                     /locus_tag="VQU30_001556"
     CDS             complement(15729..16871)
                     /locus_tag="VQU30_001556"
                     /EC_number="2.7.7.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000787267.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-1-phosphate adenylyltransferase"
                     /protein_id="HET2447638.1"
                     /translation="MKNEMLALILAGGQGTRLGKLTQSIAKPAVQFGGRYRIIDFALS
                     NCANSGIHNVGVVTQYQPLALNNHIGNGSSWGLDGINSGVSILQPYSASEGNRWFEGT
                     SHAIYQNIDYIDSVNPEYVLILSGDHIYKMDYDDMLQSHKDNNASLTVAVLDVPLKEA
                     SRFGIMNTDANNRIVEFEEKPAQPKSTKASMGIYIFDWQRLRNMLVAAEKSKVGMSDF
                     GKNVIPNYLESGESVYAYEFSGYWKDVGTIESLWEANMEYISPENALDSRNRQWKIYS
                     RNLISPPNFLGANAHVEDSLVVDGCFVDGTVKHSILSTGAQVREGAEVLDSVIMSGAI
                     IGQGAKIKRAIIGEGAIISDGVEIDGTDEVQVVGYNEVVGVATDED"
     gene            complement(16861..18789)
                     /gene="glgB"
                     /locus_tag="VQU30_001557"
     CDS             complement(16861..18789)
                     /gene="glgB"
                     /locus_tag="VQU30_001557"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1,4-alpha-glucan branching protein GlgB"
                     /protein_id="HET2447639.1"
                     /translation="MDNREALKTFMTGENFYLQHYLGAHREELNGEYGYTFRVWAPNA
                     QAVHLVGDFTNWIENQIPMVRNDFGVWEVFTNMAQEGHIYKYHVTRQNGHQLMKIDPF
                     AVRYEARPGTGAIVTELPDKKWRDGLWLARRKRWGFAERPVNIYEVHAGSWKRNPDGS
                     PYSFAQLKDELIPYLVEMNYTHIEFMPLMSHPLGLSWGYQLMGYFALEHAYGRPEEFQ
                     DFVEECHTHNIGVIVDWVPGHFTINDDALAYYDGTPTFEYQDHNKAHNHGWGALNFDL
                     GKNEVQSFLISCIKHWIDIYHLDGIRVDAVSNMLYLDYDDAPWTPNKDGGNLNYEGYY
                     FLQRLNEVIKLEYPDVMMIAEESSSATKITGMKEIGGLGFDYKWNMGWMNDILRFYEE
                     DPIYRKYDFNLVTFSFMYVFKENYLLPFSHDEVVHGKKSMMHKMWGDRYNQFAGLRNL
                     YTYQICHPGKKLLFMGSEYGQFLEWKSEEQLEWSNLEDPMNAKMKYFTSQLNQFYKDH
                     RCLWEIDTSYDGIEVIDADNRDQSVLSFIRKGKKGEMLVCIFNMVPVERKDFTIGLPV
                     AGIYEEVWNTELEEWGGVWKEHNQTVQTQEGLWKDYEQTLTFTLPAMGASVWKIKRRL
                     KSTKTVTNKNQKGVENEK"
BASE COUNT         5657 a         3987 c         3210 g         6197 t
ORIGIN      
        1 gatgacgagc gacttttttg aagcttggtt tcagaagttt ctcttaccaa cattaaccac
       61 accatcggtt attattatgg ataatgtaag attccataga atggggaagc tagaactctt
      121 gtgtgaatag tttgggcata aacttttacc tcttcctccc tactcacctg agtacaatcc
      181 tattgagaaa acatgggctc atatcaaaaa gcacctcaaa aaggtattac caagttgcaa
      241 taccttttac gaggctcttt tgtcttgttc ttgtttcaat tgactatata aattgtctaa
      301 gcgaaacagc cgataagaat tggcacaaaa gcgaccgtat ttttgttacc aatacaggaa
      361 aaacagttca tagttctatc ttgagcaagt ctctccagcg agcaaacgaa cgccttaaaa
      421 aaccaattcc caaacatctg tcccctcaca tcttcataca catcactatt agcatcttat
      481 cagaaaataa aattccttta aaaacaatca cggacagggt tggtcatccc gactctgaag
      541 tcactaattc catctacacc cacgtcacaa agaacatgaa agatgaagca atcaatgtac
      601 tggataaagt tatgaaaaag attttttaaa aagttttgtc ccttttttgc cctctaaata
      661 caaaaatagc ccttcggata aaatccgagg ggctagaaac gttgttaaat caacggccga
      721 acttttgaat ttcatggttc gggataaaat agttcactga actattttat tttttaaggt
      781 tatcataata tcaaatagtt caattaaata cgctaaatta ctaatatact ttttaccttt
      841 ttcattctaa aatgtaaagt acaaacaatt acaatatact agagggggag taaaaaaggt
      901 aataaaattg acgagttcag caggcaaggg aaatagcact tttcatggtg ttattttttt
      961 aattcagcaa tggagtagcc gcttaattga tagaaacaaa aagcacctag tttcctagat
     1021 gctagcacaa tagcccggat tcgaaccgga atctcctcaa ttaaggtgca atccctatat
     1081 actactcatt gtgctttggt tcattatatc atacaatcaa ctagctatct accaactcat
     1141 gatacgctcc catattcggt aatggaataa tactaaaata caaatctgag taagtttcaa
     1201 accatttatt cagcttgtta taggctggcg actgactaac aaataatatc cgttgacaag
     1261 ctccgataac attcatgtga ttatacacat agacctcttt aatggccgtt aaaatatcgt
     1321 cttcacttgt ctgtacccta atatctgtta tctgcttaat cgtagcgtat tttttataag
     1381 ctagcatatc tttattttta gcagcatcaa acattttaca ctcaagaaca ctatacttag
     1441 gtttttcttt atctctcatg aaataccact tgagccataa aattttttct ctgtgaatta
     1501 ctgaaatacg ttcgattttt ttctttggca tgattacctc ctaaattatt aatctaatag
     1561 ctttaaccac tcactttttg agattgttgt ataaggttca tctagcgcgt gatataaagg
     1621 ttctaaacct ttgttaaatc ggatatagtc cattttatcc tcatgctttg gaaaatataa
     1681 gattcctgtt tcatattcat ttagaccacg gttacaccaa tcatcaacga taacctgcac
     1741 ttcccattca cgccactttt taaggttttc taaaagttca atatcactaa ataactcacc
     1801 atcaacttgg aaaaattctc ccagatcatc gttaccctcg acgatgataa cttcaggcgt
     1861 atttctacta cttaataatt ccttgagttc ttgtaactct ttgatctcct ttagatactt
     1921 cctcaatttc taacctcaat tcttcaattt gtcttactac tccaaaaatt tcatgagttt
     1981 tatatgattg ttcaagtata gtttttgctg cttgagttct tataaaaggg ttaattttgg
     2041 catccatcat aatatcattg agtacagaaa cagcattgga tgaggctaga tatagcatct
     2101 gtgtagtttt atccatcatc tcatcttgtt ttagtctcaa tgtcttttta acagctgcaa
     2161 cttttagata cttatgccct gttgcccttg acacccctgc tttttggcac gctttatcta
     2221 tcgttggctc agtaagcatg gcatctatga attttatttg tttagatgta aggccatcat
     2281 tttcatttcc tgccatctat tacctcctcg ttatcaaaat aaaggggttg ctagcccctc
     2341 tatttgttta aatactcatc caaacgacgg tcaagctcag gggcatctga atttactacc
     2401 atttcagttg ttacagcttg gattttatcg ccgttgataa gcaaactgta atgacaatat
     2461 gaaagttgcc gcttaaagaa taagattaga ctttctagcg cctgctctgc attgaataat
     2521 tccaagttga tagcaatttc tggatattgt tcagcaattg accaaagttt tttaatagca
     2581 agaggtttgt tcttgtattt ttcaaaataa cctagcaatt catcctttgt catcttcata
     2641 ctagctaaca aggtcagctc tgccacgtca tcagctgtta cgctgagttc tttttctttt
     2701 aatgcctcta gctctagatc atgctgtttt tcaatttctg catgaatttt attataggtg
     2761 tccctagaat aagtgtcccc ctctaactta taagcctcta gctggtcttt agcgtatttt
     2821 tcgcctatca taccattttg taactgttta tgtaattcct cttgtttagc aatgtagcca
     2881 gtcatgtacc catgcttttt cttgccaaaa gccttaatat catccttgat tgttgtaaat
     2941 gtcatgttat cctccttacg aaaaaataaa agaggtatga caaaagagcg ttaaactcaa
     3001 ttatcatacc tctggttttt ccagtcagta tttattaaca ttgttctcca gtggtcactt
     3061 ccttataaac taactgccca tcttgagctt ttagcttaat gctaccatga tctggaattt
     3121 caatgtactt tattatacca ttttttgagt ataaaacaaa gcctttctcc atcatttcta
     3181 ataatttatt atccttgttt tcagtcatga atttctcctt tatttcaagt gtcccaacgg
     3241 gtacggttgt aagctgagac attttagggc tatctttgag cgacaaaaat gtcgaaaagt
     3301 cttcagttcc tgtataaccg ttattagttt tgtttgctac tcatttttga gtcacaaatc
     3361 tgttaagcaa aaatgagtaa tagctcgtaa gataagtaaa tctaatactt gtattcctaa
     3421 agcgttgata taactgatat tttcaactat ccaacgctct ttactaccct ttttagtgtg
     3481 ctttagctca tttttgagct tttttgagct tttttgagtt ccattttggg aatgcaaagc
     3541 aggcgcgcac cgtgcatgct tttttcttgc tcatagcctc accctcagaa gtttgccgac
     3601 cgagagcgtg gggcttttta tttttgtata attaaaaaca gctgcacaat ttttgtacag
     3661 ctacgaccga ggcaggggcg acctgccgta ctttacacta gataatatca tctaggtagt
     3721 ccaactgtat tttatcatat taaaggctac attacaattt ctcaccctgt gaagagtgtc
     3781 tatttttgtt taggtttgta agtcgattac ttcaactgct ttaccttatt ttttaactga
     3841 ttaattgagt atcgcttatc tttgattgtg aaagccttaa aagtgttacc ctcaagacct
     3901 tttagaatac ggctataatt ccgctcgttg tatactatct tgagttcatc gctatcaaga
     3961 tttgtattaa atatagtatt ttctcgatta ttcagtacat caaaaagtaa atcctgctcc
     4021 caatcgctct taggtttaat aacagcattt tttgcaccta aatcatcaat aattaagtaa
     4081 tcaacagact tcatgagttc agtagcttca aactctgtaa gtgttgcacc tttaccataa
     4141 ttccacccct ctttaatttg tttgatcatt tcggttaggc ttacaaaaag cacactctta
     4201 ggttctcctt ttgtcttata cccctcattt atacctttgg caatagcaac tgataaaagt
     4261 gtttttccaa tccctgtacc tcctgtgata agcgtatttc ccctcatgcc atcaagatat
     4321 ttttgtacct gaccttttgc aaattctaaa aatcgctttt cttctgatgt tacagcatta
     4381 aaatcatcaa aagttttagt tttaaactca tctgctacat agctcttatt gctcatcaac
     4441 acattataag tttgcagata tagtttagca ttcaaattat cagcaatcgc atcttcttca
     4501 tcttgctttt tctgttcttc ttggcattgt tcacaatagg gtgggataca gcgaacttct
     4561 tttattacct ctccgttctc attccacccc actactacat gtctttctcc tttgatttgt
     4621 gttagctgta tttcatgctt aggacacaat tcgtctagtt taaatgtctc aatatttcct
     4681 aaactagatt gtaatgattt cattttctga cctcctaaaa tggtttttct tgtgttggta
     4741 tccaatcttc atagctggta ggctctagtt gattggtttg ctgtttttta gcctcacgcg
     4801 ctgccctgct atttctaaca agttccaccg tcaataaatt gtcctgtttc caacggttaa
     4861 ggattgcctt gatgtatgca aagtttgctt taccctgact gacagcctct tttaacgcct
     4921 catggataag ctctgggcta aaatcttcta gcatatactg caattcttga atctgtaacg
     4981 gtgacaatgc tttacctgtc tcagcttcaa aagatttata gagatttaca aaatcttgat
     5041 tgatggtaga gggagtgggt gattgttctt tatctacttc tatctctaat tctttctcta
     5101 tctctgttgg acatgagttg gaaaatgtca aagatggttg gacttcttcc aattttcctt
     5161 tttttcgttg ttcacgttta taactcgccc agtttgtttc actcataacc atagcttttg
     5221 cctgtggtag ttctgcgttt ttatcttcgt caatctgtat taaaccgcat tttgtaaagt
     5281 atgccatggt catatctata tcatcttctg atacatctaa ttttagggct aactcttcct
     5341 tgagattgtt aaagtagccc tcatagtata aaatacagtc actttccaag ctctctaaca
     5401 tgagcctaat ataaataact gtcatagtgt acccaccagg taccgtcttt agtctcttga
     5461 taaaaatatt atcaaaaaat ttcttatcaa tttttagcca aaaatagact tttgtttttg
     5521 ccatcgtcct ctcccttgct catttataat tctctacctt gattagtctt aatactcgct
     5581 tgtcattcat tgttagactc attcaattct tccccatacg tctacccctg caagctggat
     5641 atatcgccca taatcagggt ttaaatcctc gctaggtgtt tctatcgtct gttggttttc
     5701 tcgctccagt tgggcgcttt ttttgcggtc tcggtggttt aaataaagca gtaagccaat
     5761 caaaatcacg gtaacaaaaa ccgcctgtgt attgcttata tctagttcat tcatgttatg
     5821 ccctcgcttt gtaattcttg atgtatgcca cttgttcagc tcgcttcata ttcaacaagt
     5881 cgtctatttc cacactggtt acttttttat ttacaaaatc agaaatcagt tgaaaaatgt
     5941 ttggactttg tagctggatt tcagccattg cctcatcaaa ttctgcttgt gtcatgttgt
     6001 ctaaatctag tgtcattgca ttgcctcctc aaacttctct ataagacaac ttttatttgc
     6061 tttctgagtt ccatttttag agttaaaaag aatatatttt aaggttacag tagcctctaa
     6121 atactccttt tcagcatgct ctatatacgc ctgttgctct gcttcgttct caaaaaagtg
     6181 cttagcttag cgtttaaaga atgctttgac taggtttagt ttgaattgcc gtactgcttc
     6241 ggtattcttt agataagtga tcagcaaagt agcctgttgc tcgttcagaa tataggattt
     6301 tttaggttgt cctctagtgt ctaatttatg gattttaaat ccaagtattc ccaactcttc
     6361 aaagtcaacc ttattttctc ttattaagcg tgtgatagtg tggtgttgta cgtcagcaca
     6421 ttcagcgatg atctcgcttg tggtatacgg ctctttcttg ccgtccatgt agactagttc
     6481 cattatggtt ctacctcctg tataaattta gctagcttac tttttaattg tctcctctag
     6541 ccctttttag cctctacaac ggttttggct aacgtgttag aggcttttat aacggcctgt
     6601 atagctgtct ctatttcctc cgtggaatag tagctttgtt ttctaatatc atttaagact
     6661 tgtttaaccc atttcttgaa ataaataaaa ttacatcttc tgtactcttg gcatctgctt
     6721 tatctgagac aaatagaatg tcaatgcctg gtagataaaa cccaccgtct atttgtttag
     6781 ttggtttgaa agtaactatt ttcatttcat aactcctatt ttattgctaa aaataaatac
     6841 acatctgaca gacgatagaa tactttctta gctccatcca tcggggtctg atatcgttta
     6901 agagcaagat cctcccagtt atcaagggtt gtagcactta tacctagcag atccattaat
     6961 tctttacgag aaattaaatc taacttacta gatcgttgtt tttctagctc aactaaagtt
     7021 tcaagagtct gtttaagaag ctgtaaaccc tgtaactgta tttctttaga cagaatttcc
     7081 atttatatcc tccattttcc tttttataaa ttaagttgtc tttttcctct aattttgata
     7141 aaataagaag agattattta gcaaaggggg ttgtcccttt gctaaatacc taacaaaacc
     7201 acgcgccttg cctttgcttg agttttgtta tttttcctta gccgtgtacg ttggtttggt
     7261 cgcctgtaca tggcttttta cttgcgttaa atttattcta ctagccaagt catcacgctc
     7321 tcatagatac gcttagaggc atcatagttt ccattctcaa cttttgttag tgtttgagat
     7381 ttaataccca actgctccga tactgctttt ttggttagct gtaatcttgc acgcttgata
     7441 cgtacttttt cagcaagtga tagtgtaatc aacattggtt tcacctccct tttttctcca
     7501 tttttggcat tttgtgttat aatctcttta gaaaggatgt ataagatgaa tagaattaag
     7561 caattacgaa aagaaaataa tcttactcaa agagaacttg ctaatgagac taaaatccct
     7621 tatagaacca tacaacgttg ggagaatggg gaaactgata taaaatccga tgctgctcag
     7681 gtacttgctg actattttgg agtatcaatt cctcacttac taggttatag cgatttgata
     7741 gcagatacag atagtgatat taaagcaatg gcatactcac atctactaac ttttgtagat
     7801 gaaaaacaaa tcaaagaatt tgaaaaagag ttcattcgtg caaacgataa tagtgatact
     7861 tttggtgatt taggaagtgg tgaaaaggcg ttagaaaaat actatcaagc attatgctat
     7921 ttagttcctc cttttaggga tatattggct aggtatagct ttttgtcact agatgaaaaa
     7981 aaatcagtct ataatattat tgttggttta agtaacaact tatcaaaaga aaataaataa
     8041 ctttaaacat catgtataaa tacctaacaa aaccacgcgc cttgcctgct gatggaaaga
     8101 aaggtacaaa tacatgaata tcatagagaa aattaaaaag aatggccaaa gagtttatta
     8161 tgctagtgtt tatctaggcg ttgaccaact aacgggcaaa aaagcccgta caactgttac
     8221 agcaaccact aaaaagggcg ttaaagtaaa agcgcgtgat gcgatcaata cttttgctgc
     8281 taatggctat acagttaaag ataagccgac aattacaaca tacaatgagc ttgtaaaagt
     8341 ttggtgggat agttacaaga atacagttaa gccaaatact cgccaatcca tggatggatt
     8401 ggttagagtg catttattgc ctgtatttgg cgattacaag ctatctaaac ttactacgcc
     8461 tattcttcaa cagcaagtaa acaaatgggc tgacaaggca aataaaggcg aaaaaggggc
     8521 atttgctaac tactccttgc tccataacat gaataagcgt attttgaaat atggcgtagc
     8581 tatccaggta atacaataca acccagctaa tgatgtcatc gttccacgca aacagcagaa
     8641 agaaaaggct gctgtcaaat acttagacaa caaagaatta aaacagtttc ttgattattt
     8701 agacactctg aatcaatcaa attatgagaa cttatttgat gttgtcctgt ataagacttt
     8761 attggccact ggttgccgta ttagtgaggc tctagctctt gaatggtctg atattgacct
     8821 agaaagcggt gttatcagca tcaataagac actaaaccgc tatcaggaaa taaattcacc
     8881 taaatcaagc gctggttatc gtgatatacc aatagacaaa gccacattac ttttactgaa
     8941 acaatacaaa aaccgtcaac aaattcagtc ttggaaatta ggccgatctg aaacagttgt
     9001 attctctgta tttacggaga aatatgctta tgcttgtaac ttacgcaaac gcctaaataa
     9061 gcattttgat gctgctggag taactaacgt atcatttcat ggtttccgcc atacacatac
     9121 tactatgatg ctctatgctc aggctagccc gaaagatgtt cagtatagat taggccactc
     9181 taatttaatg atcactgaaa atacttactg gcatactaac caagagaatg caaaaaaagc
     9241 cgtctcaaat tatgaaacag ctatcagcaa tttataaaaa ataagggtga cccatttccg
     9301 ggctaccctc ttactatacc aaaaattagt aggggtagta aaaagggtat taaattataa
     9361 aaagcactaa gggaaagcgc cccaaagtgc ttatttcaaa ggctttatag cctataatca
     9421 cataaggaga ttatttttta aggttgtaga atgatttcaa tccacgatat tcagctactt
     9481 caccaagttg gtcttcgata cgaagcaatt ggttgtattt agcgatgcgg tctgtacgtg
     9541 aaagtgaacc agtcttgatt tgtcctgcgt tagttgcaac tgcaatatca gcgattgttg
     9601 aatcttcagt ttcacctgaa cggtgtgata caacagcagt gtaaccagct tctttagcca
     9661 tttcgatagc ttcaaaagtt tcagtaagag taccgatttg gttaactttg ataaggattg
     9721 agttagcagc accttcttgg ataccacgtg caaggtagtc agtgtttgtt acgaagaagt
     9781 cgtcaccaac aagttgtact ttcttaccaa gacgttcagt aagagctttc caaccatccc
     9841 agtcgttttc atccatacca tcttcaatag tgatgattgg gtatttgtta accaattctt
     9901 caaggtagtc gatttgttct gcagatgtac gaacagcagc accttcacct tcaaatttag
     9961 tgtagtcgta aactttacgt tctttatcgt agaattctga tgaagcacag tcaaatccga
    10021 taaatacgtc tttacctggt acatatccag cagcttcaat cgcagcaagg atagtttcaa
    10081 caccatcttc agttccttcg aaacgaggag cgaatccacc ttcgtcacct acggcagttt
    10141 ccaaaccacg tgatttaagg attttcttaa gagcgtggaa gatttcagca ccgtaacgaa
    10201 gggcttcttt aaatgttggc gcaccaactg gcaagatcat gaactcttgg aaagcgattg
    10261 gagcgtcaga gtgagaacca ccgttgatga tgttcatcat tggagttgga agaactttag
    10321 tgttgaatcc accaaggtag ctgtaaagtg ggatttcaag gtagtcagca gcagcacgag
    10381 ctacagcgat agacacaccg aggattgcat tcgcacccaa tttacctttg ttaggagtac
    10441 cgtcaagtgc gatcatagca cggtcaatag cttgttgatc acgtacatcg tagccaatga
    10501 tagcttcagc aatgatgttg tttacgttgt caacagcttt ttgtgtacca agaccaccgt
    10561 aacgagattt gtcaccgtcg cgaagttcaa ctgcttcgtg ttcaccagta gaagctcctg
    10621 atggaaccat accacgtccg aaagcacctg attcagtgta aacttctact tcaagtgttg
    10681 ggttaccgcg tgagtctagg acttcgcgag cgtaaacatc agtaataatt gacatttttt
    10741 actctcctta tgagttaaat tttttacacc tctataatac cttaaaaccc ctcctttttc
    10801 aagaaaaaac gttatctttg tgcaactttt ccttaacttt ataaagtaat cgctttcttt
    10861 tgtctgtttt attctaactt ttatgatata ctgttttcat gacagattta tcaaaacaat
    10921 tacttgaaaa agctcatggt gggttaaaaa taaatccgga tgagcaaaga cgctatcttg
    10981 gtacttttga ggaaagagtt cttggatatg tagatattga cacagcaaat agccctcagt
    11041 tagaaaaagg ctttttattt attttagaaa accttcagga aaaagcagag ccactatttg
    11101 tgaagatttc accaactatc gaatttgata agcaagtttt ctacttaaaa gaagcaaaag
    11161 aaactgatag tcaagccacc atagtatctg aagagcatat tacttctcct tttggcctgg
    11221 ttattcatag caatgcacca gttcaagtag aagaaaaaga ccttcgactt gcttttccaa
    11281 aactttggga agttaaaaag gaagaaccag ccaaaacatc cttatggaag aaatggttta
    11341 gctaaatctt gcacatattt aataagtgcc caatattggc agccgtgcgc tccagataga
    11401 gactggcatt tttcaaacta tcttctaaag gttcactttt ctccaaaata gaaaagacag
    11461 cttggatatt ttcaaatggt aggggaggta aatcttcagc aagactaccg caaatagcaa
    11521 taacaggaac tccaacaggg gttctttttg caacacctat aggcgctttc ccagcaaagc
    11581 tttgactatc aagtcttcct tctccaacaa caaccaagtc agcatctgaa actttcttat
    11641 caaagttgat taagtccaag caggtatcaa ttccagacac gatacttgcc tgagcaaaag
    11701 cacacaaacc accagcaagg cctccacctg ctcctgctcc tttaatttct aatgttgcag
    11761 gtgagaattt ttcataaaaa tcttggatcg cctgatctac gactgcaaac atagtcggat
    11821 gtcgaccttt ttgattgcca aaagtataag tcgcaccttg atgaccacat aagggactta
    11881 cgacatctgc taaaatatga atttgaacac cttcaggaat tttatagcaa ttttctgttg
    11941 aaacagaagc taagtttaat aaggattgac cggaagcagg caagacattt ccatccctat
    12001 cataaaattg ataacctaaa ccagcagcaa tccccagtcc tccatcatta ctggccgtgc
    12061 caccaacatc gatataaata tctttaatcc ctttagaaat gagatggaga atcaactctc
    12121 caataccaca agtttggatt tgaagtggat ttcgtttctc tagcggaatt tttccaagac
    12181 caaccaagtc agctacttca aatagtgcca gttccccttt ttgaaaatag cgcatggctt
    12241 ctttttgtcc aaaagggtct gtcacttgga tccatttttc ttttaggtca agagaatgtc
    12301 ggatagcatc tacagtacct tctcccccat caccaacagg gcagaggaga cattctacat
    12361 ctgctatcga ttgttggaag cctcttttta ttgcttcagc tacctgttga gctgtcaagc
    12421 tttccttaaa cgaatccggt gcaattacaa tcttcatatt ttccctcatt ctaaacagtc
    12481 aatcaaagga agaacttcta aaaaatccct cttgtcaaca tgatgtggta tttctttttt
    12541 gagcatttct ttggaacaaa aggcgattcc taactccgcc gacttcaaca ttaatagatt
    12601 attgccccca tcaccgattg ccaccgttct ttctttagaa agttttagtt tctttctcca
    12661 tttttccaga gtttcttttt tgacctgggg acttataatt tgtccaacta attttcctgt
    12721 taaaagacct tctttgactt caagctggtt agcagtgaaa taggcaatac caagggattt
    12781 tgctaatctc tccaactatt ggtgtaaatc caccagacac cagaccaact aggataccat
    12841 tcttttggag aatagagatg aactctggga catttagcga tagatgaatt gagttgaaga
    12901 cgttatcaaa gaccaaaata ggaagacctt ccaacaagga cactcttttt cttaaactgc
    12961 tttcaaagac caactctcct cgcattgctc gacttgtaat ctgcgaaatt tctgcctcat
    13021 gacctgcctc tctccctaaa agatcaatca cttcttctag gattaaggtt ccatctacat
    13081 ccaaaacaca caagcctttt acttgagaca tcagttctcc tctctaaaca gcctaaaaat
    13141 cgtatgaagt catcatacga ttttatctat taattaacta aactatggta caagtcaagg
    13201 tatgacttgc aggctgtatc ccatgagaag tcactctcca tagcttgttt ttgtaggttt
    13261 ctccaaatgt ctggatggtt tctatacaag tccaatgctg tttggaaagt ccaatttaac
    13321 caataaggag atagattgtc aaagctaaag ccagtaccgc ttccttcgat tggattgaaa
    13381 gcgcgaactg tatctcgcaa gcctccaact tcatggacca atggcaaggt tccataacgc
    13441 atagccatca tttgagacaa gccacacggt tcaaaacgac ttggcatgag gaagaggtca
    13501 caagcagcgt agatttcctg agcaagtttg acatcaaaag tgatatttgt tgatagcttg
    13561 tctgggtaaa tctgagcaaa ccatgagaaa gctccttcaa aggctggatc gccagttccc
    13621 aaaagaacaa tctgaacatc ttcttgcaag atatggtgaa gactttcgac caccacatca
    13681 aaaccttttt gacgtgtcaa acgagaaaca attcccacca gtggaacgtc tgctctaaca
    13741 ggcaagccaa ctctttcttg caattttgcc ttatttttgg ctttcccaga caaatcttcc
    13801 tgattgaaat gatagtctaa aagagcatcc gtctgaggat tataaagatc agcatcaatc
    13861 ccattcacga taccagatac tttaccagac tccattttaa gaatctgatc caaattacat
    13921 ccaaactgac tagtcataat ttcatgagca tagctaggtg aaacggttga aacacggttc
    13981 gcatagagaa tacctgcctt catccagttc agacagttgt tccatcgaag ggtgccatca
    14041 gcgtaacgtt caaagccaac tccaaacaaa tcacccaaca ttccttctga aaattgtcct
    14101 tggaattcta aattatgaat ggttaaaact gtttcaatgt cctcataggc ttgaatccaa
    14161 cggtattttt ccttcaacaa gaaaggaatc atagctgtat ggtagtcatg aacatggaga
    14221 agatcaggaa taaagtcaat cctttccata gcctcaatgg cagccagttg gaaaaaggca
    14281 aagcgttctc cgtcatcaaa atcaccgtaa acatgaccac ggaagaaata atattgattg
    14341 tcaataaagt agaaggttac accatttaat actgttttct taattccaca atactgtctg
    14401 cgccaaccaa cgctcacctc aaaatgaagc acatcttcaa tctgatttcc aaatttagcc
    14461 tctaccatat catagtaggg taaaatcact gcaacttcgt gcccagcttt taccagtgat
    14521 tttggaagag cgccaatgac gtctcccaaa ccacctgttt ttgaaaaggg tgcaccctct
    14581 gctgctacaa ataaaatttt catgaatgaa tatcctctgt tactttagca cctttcttaa
    14641 ccacaactgg atgttctgca gttcctcgaa tcacaacacc aggctcaact tcaacccctt
    14701 tgtccaagat agcatattcg acctgagccc cttctccaat aacaacacga gggaagagca
    14761 ggctatcttt aaccaagcta tccttatgga catggatatt acgtgataga acagaattag
    14821 ctacttgacc ttcaataata ctaccagagg caaactgaga agttcttacc ttagatgtat
    14881 tagcatagta agttggctct tcgtttttga cctttgtata aatcttttgg tttggtgaga
    14941 aaagagaata gaatttttgt gattcaagca tatcgatatt cgcttgataa taagatttaa
    15001 cagagtgaat attggctaga tagcccgtgt actcgtaggc gaaagctccc tcttttacag
    15061 ccaaatcccg taaaacatag cgcaatttct ctggatgttc ttttttagct tcttcttcca
    15121 agtgttcaat caaccaaggt gtatcaacga caaagatatc tgtagacata ttgaacgttt
    15181 cagctgttga cttgctatca aagagtttat gagaaagaac atggtctgtt tcatctacat
    15241 ccaagattgc atttacttct gaaatatctt tcttagctag ttttttataa actacagtga
    15301 taggctcttt tgttgtacta tgtaggtgga aaacttggtt caaatcaatg ttaataagaa
    15361 catcgcagtt gagggcaacc gtttggtttg agccagaacg tttcaaataa gtaagaagct
    15421 gttggtagta ttcttttcca actgtactac tttctacacg ggtattgtaa attcctagat
    15481 agtaatggct aagaaaggtt gataagcccc actcgcgtcc tgaacgaata tggtcaaata
    15541 ctgagctgat attatcctgc tggaaaatac caaagacact acgaacacct gcattagcaa
    15601 ggcttgaaag tgggaagtca atcaaacgat atttcccacc aaatggcaaa cttgctactg
    15661 gacggtggtc cgtcaatgtc gacatattgt gaaaaccaac tgtatttcct aaaatggcag
    15721 aatatttatc aatcttcatc tgttgctacc cccactactt cattatatcc tacaacttgt
    15781 acttcatctg ttccatcaat ttcgacaccg tcagaaataa tcgcaccttc accaataatg
    15841 gcacgtttaa tcttagctcc ttgaccaatg atagctccac tcatgataac tgaatcaagg
    15901 acttccgctc cttcgcgaac ttgcgcgcct gttgaaagga tagaatgttt aacagttcca
    15961 tcaacgaaac atccgtctac aactaatgag tcttccacat gagcatttgc cccgaggaag
    16021 tttggtggtg aaatcaagtt tcttgagtaa atcttccatt gacggttacg actatccaag
    16081 gcattttctg gagaaatata ctccatgttc gcttcccaaa gtgactcaat agtaccaaca
    16141 tctttccaat aaccactaaa ttcgtaagca taaacacttt cacctgactc aaggtaattt
    16201 ggaatgacat ttttaccaaa gtctgacatg ccaaccttgc tcttttcagc agcgactaac
    16261 atattacgaa ggcgttgcca atcaaaaatg tagattccca tagaagcttt tgtagattta
    16321 ggttgagctg gtttttcttc aaattcaaca atacgattgt tagcatctgt gttcatgata
    16381 ccaaaacggc ttgcttcttt aagagggacg tctaaaactg ctactgtcaa gctggcatta
    16441 ttatccttat gagactggag catatcatca tagtccattt tgtagatgtg atccccagac
    16501 aaaatcaaga catactcagg attgacactg tcgatatagt cgatattttg gtaaatagcg
    16561 tgactagtcc cctcaaacca acgatttcct tcacttgcag aataaggttg aagaatagag
    16621 acacctgaat taataccgtc tagtccccag cttgaaccat tcccaatatg gttgttgaga
    16681 gcaagtggtt gatactgtgt aacgacccca acattatgaa tccctgagtt ggcacagttt
    16741 gatagggcaa agtcaatgat acggtagcgc ccaccaaatt gcacagctgg ttttgcgatg
    16801 ctttgagtga gtttaccgag acgagttcct tgcccaccag caagaatcaa agctaacatt
    16861 tcatttttca ttttctactc ctttttggtt tttatttgtg acggttttag tagatttcaa
    16921 gcgacgtttg attttccata cacttgctcc catagccggt agggtaaagg ttaaggtctg
    16981 ctcataatct ttccatagtc cttcttgcgt ttgaacagtt tgattatgtt ctttccaaac
    17041 gcctccccac tcttccaact cagtattcca tacttcttcg taaattcctg caacgggtag
    17101 tccgattgta aaatctttcc gctcaacagg taccatgtta aagatacaga ctaacatttc
    17161 tcccttttta cccttacgaa taaaggaaag aacactctgg tctcgattat ccgcatcaat
    17221 gacttcaata ccatcatagc tggtatcgat ttcccacaga cagcgatgat ctttgtaaaa
    17281 ctggtttagc tgagaagtga aatacttcat cttagcattc attgggtctt ctaggttaga
    17341 ccattccaac tgttcttcag atttccattc taggaattga ccgtattcgc tacccatgaa
    17401 gagcaatttc ttaccagggt gacaaatttg gtacgtatag agattgcgca agcctgcgaa
    17461 ttgattgtaa cgatctcccc acatcttatg catcatactc ttcttgccat gaaccacttc
    17521 atcgtgcgag aatggcaaga gataattctc cttgaaaaca tacataaagc tgaaagtcac
    17581 caggttaaag tcatatttac gataaatcgg atcttcttcg tagaaacgga ggatatcatt
    17641 catccagccc atgttccatt tgtagtcaaa tcctagacca ccaatctctt tcattcccgt
    17701 aatcttggtt gcagacgaac tttcttctgc aatcatcatc acatctggat attctaactt
    17761 aataacttca ttcaagcgtt gaaggaaata ataaccttca tagttgagat ttccgccatc
    17821 tttattaggt gtccatggag catcatcata gtccaaatag agcatgttgc taacagcatc
    17881 cacacgaata ccatccaaat gatagatatc aatccaatgc ttaatgcaag aaattaagaa
    17941 ggactggact tcattttttc caaggtcaaa attaagggca ccccaaccat ggttatgagc
    18001 cttattatgg tcttggtatt caaaagtcgg tgtcccatca taataggcta aggcatcatc
    18061 attgatggta aagtgacctg gtacccagtc cacaataacc ccaatattat gggtatgaca
    18121 ctcctcgaca aaatcttgaa actcctctgg tctaccatag gcatgctcta aagcgaagta
    18181 acccataagc tggtaccccc aactcaaacc tagtgggtgg gacatcaagg gcataaactc
    18241 aatatgagta tagttcatct caactaggta aggaatgagt tcatctttca attgggcaaa
    18301 actataagga ctgccatcag gatttctctt ccaagagcca gcatgaacct cgtaaatatt
    18361 gacaggacgt tcagcaaagc cccaacgttt tcttcgtgcc agccaaagtc catccctcca
    18421 tttcttatca ggaagctctg ttacgattgc ccctgttcct ggacgagcct catacctgac
    18481 agcaaaaggg tcaatcttca tcagttgatg accattttga cgtgtgacat gatatttgta
    18541 aatatgccct tcttgagcca tattggtaaa gacttcccag accccaaagt catttcttac
    18601 cattggaatc tgattttcaa tccaattggt aaaatcacca accaagtgaa cagcctgagc
    18661 attaggtgcc caaacacgga aggtatagcc atactctcca tttagttctt ccctatgtgc
    18721 tcctagataa tgttggagat aaaaattttc acccgtcata aaggttttta atgcttctct
    18781 attatccata tactcccttt ctcctgtaag cgttttctat gtttttatta tactaccttt
    18841 ttagagaaga ttcaagtaaa ttactatact tctttaatta ttttgaaaat ctacaacaag
    18901 ttcacttact cgttcaattg taaatcaata ttttttcaaa aaattgcgaa aacacctttc
    18961 tttttctact atagtgaaat gaaataaaac atgcgcaaat cgattaagga atttaatcta
    19021 atttctaaca atgtcttaga aatcaaagtg t
//
LOCUS       DAVBBO010000045        18358 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ST1
            SAMEA2066453-rid20184263.denovo.045, whole genome shotgun sequence.
ACCESSION   DAVBBO010000045 DAVBBO010000000
VERSION     DAVBBO010000045.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2066453
            Sequence Read Archive: ERR351777
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 18358)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 18358)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980402.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980402.1
            Genome Coverage       :: 176x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:17:33
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,141
            CDSs (total)                      :: 2,104
            Genes (coding)                    :: 1,953
            CDSs (with protein)               :: 1,953
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 16S)
            partial rRNAs                     :: 1 (23S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 151
            CDSs (without protein)            :: 151
            Pseudo Genes (ambiguous residues) :: 0 of 151
            Pseudo Genes (frameshifted)       :: 73 of 151
            Pseudo Genes (incomplete)         :: 76 of 151
            Pseudo Genes (internal stop)      :: 40 of 151
            Pseudo Genes (multiple problems)  :: 32 of 151
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..18358
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2066453-rid20184263.denovo.045"
                     /strain="ST1"
                     /db_xref="taxon:1313"
     gene            16..86
                     /locus_tag="VQU30_001558"
     tRNA            16..86
                     /locus_tag="VQU30_001558"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:48..50,aa:Gly,seq:tcc)
     gene            122..195
                     /locus_tag="VQU30_001559"
     tRNA            122..195
                     /locus_tag="VQU30_001559"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:156..158,aa:Ile,seq:gat)
     gene            202..289
                     /locus_tag="VQU30_001560"
     tRNA            202..289
                     /locus_tag="VQU30_001560"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:236..238,aa:Ser,seq:gct)
     gene            complement(423..860)
                     /locus_tag="VQU30_001561"
     CDS             complement(423..860)
                     /locus_tag="VQU30_001561"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000436265.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
                     /protein_id="HET2447640.1"
                     /translation="MEQLHFITKLLDIKDPNIKILDIINMDTHKEIIAKLDYEAPSCP
                     DCGSLMKKKEPEKFFGLIEDNLKQVHPIFQTVFKTFLKDKEKIVNALQLHYSNAKLEA
                     TNNLIKLIKCNAFGFRNFENFKKRIFIALNIKKERTKFVLSRA"
     gene            complement(1111..2046)
                     /locus_tag="VQU30_001562"
     CDS             complement(1111..2046)
                     /locus_tag="VQU30_001562"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000844514.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional biotin--[acetyl-CoA-carboxylase]
                     synthetase/biotin operon repressor"
                     /protein_id="HET2447641.1"
                     /translation="MKSYQAVYQILSKETDYISGEKIAEKLSLSRTAIWKAIKRLEQE
                     GIEIDSIKNRGYKLMNGDLILPEILEENLPIKVSFKPETKSTQLDAKEAIDLGHEANT
                     LYLASYQTAGRGRFQRSFYSPQGGIYMTLHLKPNLPYDKLPSYTLLVAGAVYKAIKNL
                     TLIDVDIKWVNDIYLNNHKIGGILTEAMTSVETGLVTDIIIGVGINFTIKDFPQELKE
                     KAASLFKATAPITRNELIIEIWRAFFETPAEELLYLYKKQSFILGKEVTFTLEQKDYK
                     GLAKDISENGKLLVQCDNGKEIWLNSGEISLNSWK"
     gene            complement(2043..2903)
                     /locus_tag="VQU30_001563"
     CDS             complement(2043..2903)
                     /locus_tag="VQU30_001563"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000959966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HET2447642.1"
                     /translation="MLVFSEYQTGTIDLALSFYGYEECTPNYSFGPAIRDTYVLHYIT
                     KGQGKFYYKGKIVDLKEGDFFLLKPEELTFYQADSKEPWAYYWLGITGGKSPDYFALS
                     QISDQSYLIQSETCHTQTTAKLISDIVRFAQITKSSELAQLHIMGQLHELMFHLGTIA
                     PNQKKKNISSTHQLYLECKRLIDSHYPQSLTIQDLAKELSVHRSYLSSVFKEFNTLSP
                     KEYLLYVRMHRARQLLENTQESIKVIAYSVGFSDPLHFSKAYKQYFNQTPSHTRKEYS
                     QYQLVRKATL"
     gene            3011..5173
                     /locus_tag="VQU30_001564"
     CDS             3011..5173
                     /locus_tag="VQU30_001564"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000538915.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-galactosidase"
                     /protein_id="HET2447643.1"
                     /translation="MGVRIENNLFYVESKNLSLIIENRNGYLLLKHLGKTIKNYKGSN
                     SVYERDHAFSGNPTATNRTFSLDTQRQIFGQHGLGDFRKPTIQVQHSVTEVTDFRFVE
                     AKILKGQNGPQGLPSPHSMDDTETLVLMLEDSKAQLSLTLYYTTFNNDATITSYSKLD
                     NNSNQEVVIHKDFSFMADFPAADYEIATLQGAYAREKTVRRQQVEQGIFSISSNRGAS
                     GHAQTPALLLCEQGVTEDAGNVFAIQLMYSGNFEAFVQKNQLNEVRVAIGINPENFSW
                     KLAPEEYFETPVALVTHSDQGLTGISHESQNFVLKHIILSEFSKKERPILINNWEATY
                     FDFQREKLLELADEAKKVGIELFVLDDGWFGNRFDDNRALGDWVVNEEKLGGSLESLI
                     SAIHERGLQFGLWLEPEMISVDSDLYRQHPDWAIQVPDYEHTYSRNQLVLNLANPQVV
                     EYLKSVLDQLLSYHEIDYIKWDMNRNITKLGNGLTYLETQMQSHQYMLGLYELVSYLT
                     EKHSHILFESCSGGGGRNDLGMIRYFPQVWASDNTDAIARLPIQYGSSYFYPTISMGA
                     HVSAVPNHQMGRMTPLETRGHVAMMGNLGYELDLTNLSDEEKATIANQVNLYKELRPV
                     VQLGQQYRLINPDTASNEAAVQFNYGNQTIVTYVRVLSVVETMETTLKLKDLDEEGLY
                     KLQENGEVYSGAELMYAGLTVILSQGDFLSRQYIFRKL"
     gene            5265..6524
                     /locus_tag="VQU30_001565"
     CDS             5265..6524
                     /locus_tag="VQU30_001565"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399433.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HET2447644.1"
                     /translation="MEWYKKIGLLATTGLALFGLGACSNYGKSADDTVTIEYFNQKKE
                     MTKTLEEITRDFEKENPKIKVKVVNVPNAGEVLKTRVLAGDVPDVVNIYPQSIELQEW
                     AKAGVFEDLSNKDYLKRVKNGYAEKYAVNEKVYNVPFTANAYGIYYNKDKFEELGLKV
                     PETWDEFEQLVKDIVAKGQTPFGIAGADAWTLNGYNQLAFATATGGGKEANQYLRYSQ
                     PNAIKLSDPIMKDDIKVMDILRINGSKQKNWEGAGYTDVIGAFARGDVLMTPNGSWAI
                     TAINEQKPNFKIGTFMIPGKEKGQSLTVGAGDLAWSISATTKHPKEANAFVEYMTRSE
                     VMQKYYDVDGSPTAIEGVKQAGEDSPLAGMTEYAFTDRHLVWLQQYWTSEADFHTLTM
                     NYVLTGDKQGMVNDLNAFFNPMKADVD"
     gene            6538..7404
                     /locus_tag="VQU30_001566"
     CDS             6538..7404
                     /locus_tag="VQU30_001566"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000757171.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HET2447645.1"
                     /translation="MKKVLQKYWAWAFVVIPLLLQAIFFYVPMFQGAFYSFTNWTGLT
                     YNYKFVGLNNFKLLFMDPKFMNAIGFTAIITIAMVVGEIALGIFIARVLNSKIKGQTF
                     FRAWFFFPAVLSGLTVALIFKQVFNYGLPAIGNALHIEFLQTSLLGTKWGAIFAAVFV
                     LLWQGVAMPIIIFLAGLQSIPTEITEAARIDGATSKQVFWNIELPYLLPSVSIVFILA
                     LKGGLTAFDQVFAMTGGGPNNATTSLGLLVYNYAFKNNQFGYANAIAVILFFLIVVIS
                     IIQLRVSKKFEI"
     gene            7418..8251
                     /locus_tag="VQU30_001567"
     CDS             7418..8251
                     /locus_tag="VQU30_001567"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000711263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HET2447646.1"
                     /translation="MKQDERKALIGKYILLILGSVLILVPLLATLFSSFKSTKDIVDN
                     FFGFPTNFTWDNFSRLLADGIGGYYWNSVVITVLSLLAVMIFIPMAAYSIARNMSKRK
                     AFTIMYTLLILGIFVPFQVIMIPITVMMSKLGLANTFGLILLYLTYAIPQTLFLYVGY
                     IKISIPESLDEAAEIDGANQFTTYFRIIFPMMKPMHATTMIINALWFWNDFMLPLLVL
                     NRDSKMWTLPLFQYNYAGQYFNDYGPSFASYVVGIISITIVYLFFQRHIIAGISNGAV
                     K"
     gene            8252..8332
                     /locus_tag="VQU30_001568"
                     /pseudo
     CDS             8252..8332
                     /locus_tag="VQU30_001568"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820552.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopuranose mutase"
     gene            8470..9912
                     /gene="gtfA"
                     /locus_tag="VQU30_001569"
     CDS             8470..9912
                     /gene="gtfA"
                     /locus_tag="VQU30_001569"
                     /EC_number="2.4.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001122330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sucrose phosphorylase"
                     /protein_id="HET2447647.1"
                     /translation="MPIQNKTMLITYSDSLGNNLKDLYDNLEEHFGDAIGGVHLLPFF
                     PSTGDRGFAPVDYDEVDSAFGDWEDVKRLGEKYYLMFDFMINHISRQSKYYKDYQEKH
                     EASEFKDLFLNWDKFWPENRPTQSDVDLIYKRKDRAPKQEIVFEDGSVEHLWNTFGEE
                     QIDLDVTKEVTMEFIRKTIQHLASNGCDLIRLDAFAYAVKKLDTNDFFVEPDIWDLLD
                     KVRDIAAEYGTEILPEIHEHYSIQFKIADHDYYVYDFTLPMVTLYTLYSSRTERLAKW
                     LKMSPMKQFTTLDTHDGIGVVDVKDILTDEEIDYASNELYKVGANVKRKYSSAEYNNL
                     DIYQINSTYYSALGDDDVKYFLARLIQAFAPGIPQVYYVGLLAGKNDLKLLEETKEGR
                     NINRHYYSNEEIAREVQRPVVKALLNLFSFRNRSEAFDLEGTTEIETPTAHSIVIKRQ
                     NKDKSVTAVAEIDLQNQTYRVIENGVEVSF"
     gene            10050..11243
                     /locus_tag="VQU30_001570"
     CDS             10050..11243
                     /locus_tag="VQU30_001570"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008293041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="O-antigen ligase family protein"
                     /protein_id="HET2447648.1"
                     /translation="MKSIGFIEKLKGLSSKELILLGIILSIFLPFYLFVVVLCLYIIS
                     LIFTGDMKSILQKMGEHPMLLLFLSYSTVISILAQNWMGLVASVGMFLFTIFFLHYQS
                     ILSHKFFRLILQFVLFGSVLSAAFASLEHFQIVKKFNYAFLSPNMQVWHQNRAEVTFF
                     NPNYYGIICCFCIMIAFYLFTTTKLNWLKVFCVIAGFVNLFGLNFTQNRTAFPAIIAG
                     AIIYLFTTIKNWKAFWLSIGVFAIGLSFLFSSDLGVRMGTLDSSMEERISIWDAGMAL
                     FKQNPFWGEGPLTYMHSYPRIHAPYHEHAHSLYIDTILSYGIVGTILLVLSSVAPVRL
                     MMDMSQESGKRPIIGLYLSFLTVVAVHGIFDLALFWIQSGFIFLLVMCSIPLEHRMLV
                     SDMTD"
     gene            11930..13909
                     /locus_tag="VQU30_001571"
     CDS             11930..13909
                     /locus_tag="VQU30_001571"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000742236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide ABC transporter substrate-binding
                     protein"
                     /protein_id="HET2447649.1"
                     /translation="MKKNRVFATAGLVLLAAGVLAACSSSKSSDSSAPKAYGYVYTAD
                     PETLDYLISSKNSTTVVTSNGIDGLFTNDNYGNLAPAVAEDWEVSKDGLTYTYKIRKG
                     VKWFTSDGEEYAEVTAKDFVNGLKHAADKKSEAMYLAENSVKGLADYLSGTSTDFSTV
                     GVKAVDDYTLQYTLNQPEPFWNSKLTYSIFWPLNEEFETSKGSDFAKPTDPTSLLYNG
                     PFLLKGLTAKSSVEFVKNEQYWDKENVHLDTINLAYYDGSDQESLERNFTSGAYSYAR
                     LYPTSSNYSKVAEEYKDNIYYTQSGSGIAGLGVNIDRQSYNYTSKTTDSEKVATKKAL
                     LNKDFRQALNFALDRSAYSAQINGKDGAALAVRNLFVKPDFVSAGEKTFGDLVAAQLP
                     AYGDEWKGVNLADGQDGLFNADKAKAEFAKAKKALEADGVQFPIHLDVPVDQASKNYI
                     SRIQSFKQSVETVLGVENVVVDIQQMTSDEFLNITYYAANASSEDWDVSGGVSWGPDY
                     QDPSTYLDILKTTSSETTKTYLGFDNPNSPSVVQVGLKEYDKLVDEAAKETSDLNVRY
                     EKYAAAQAWLTDSSLFIPAMASSGAAPVLSRIVPFTGASAQTGSKGSDVYFKYLKLQD
                     KVVTKEEYEKAREKWLKEKAESNEKAQKELASHVK"
     gene            13976..15326
                     /locus_tag="VQU30_001572"
                     /pseudo
     CDS             13976..15326
                     /locus_tag="VQU30_001572"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000759888.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
     gene            15326..16252
                     /locus_tag="VQU30_001573"
     CDS             15326..16252
                     /locus_tag="VQU30_001573"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730677.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HET2447650.1"
                     /translation="MSTIDKEKFQFVKRDDFASETIDAPAYSYWKSVFKQFMKKKSTV
                     VMLGILVAIILISFIYPMFSKFDFNDVSKVNDFSIRYIKPNAEHWFGTDSNGKSLFDG
                     VWFGARNSILISVIATVINLVIGVFVGGIWGISKSVDRVMMEVYNVISNIPPLLIVIV
                     LTYSIGAGFWNLIFAMSVTTWIGIAFMIRVQILRYRDLEYNLASRTLGTPTLKIVAKN
                     IMPQLVSVIVTTMTQMLPSFISYEAFLSFFGLGLPITVPSLGRLISDYSQNVTTNAYL
                     FWIPLTTLVLVSLSLFVVGQNLADASDPRTHR"
     gene            16261..17328
                     /locus_tag="VQU30_001574"
     CDS             16261..17328
                     /locus_tag="VQU30_001574"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866499.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET2447651.1"
                     /translation="MTKEKNVILTARDIVVEFDVRDKVLTAIRGVSLELVEGEVLALV
                     GESGSGKSVLTKTFTGMLEENGRIAQGSIDYRGQDLTALSSHKDWEQIRGAKIATIFQ
                     DPMTSLDPIKTIGSQITEVIVKHQGKTAKEAKELAIDYMNKVGIPDADRRFNEYPFQY
                     SGGMRQRIVIAIALACRPDVLICDEPTTALDVTIQAQIIDLLKSLQNEYHFTTIFITH
                     DLGVVASIADKVAVMYAGEIVEYGTVEEVFYDPRHPYTWSLLSSLPQLADDKGDLYSI
                     PGTPPSLYTDLKGDAFALRSDYAMQIDFEQKAPQFSVSETHWAKTWLLHEDAPKVEKP
                     AVIANLHDKIREKMGFAHLAD"
     gene            17339..18265
                     /locus_tag="VQU30_001575"
     CDS             17339..18265
                     /locus_tag="VQU30_001575"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001291287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET2447652.1"
                     /translation="MSEKLVEIKDLEISFGEGSKKFVAVKNANFFINKGETFSLVGES
                     GSGKTTIGRAIIGLNDTSNGDIIFDGQKINGKKSREQAAELIRRIQMIFQDPAASLNE
                     RATVDYIISEGLYNHRLFKDEEERKEKVQNIIREVGLLAEHLTRYPHEFSGGQRQRIG
                     IARALVMQPDFVIADEPISALDVSVRAQVLNLLKKFQKELGLTYLFIAHDLSVVRFIS
                     DRIAVIYKGVIVEVAETEELFNNPIHPYTQALLSAVPIPDPILERKKVLKVYDPSQHD
                     YETDKPSMVEIRPGHYVWANQAELARYQKGLN"
BASE COUNT         5400 a         3255 c         3840 g         5863 t
ORIGIN      
        1 attgatagta tttatgcggg tgtagtttag tggtaaaact acagccttcc aagctgttgt
       61 cgcgagttcg attctcgtca cccgctttga actttgttca aattaccaag ttttttaact
      121 tgggcgcgta gctcaggtgg ttagagcgca cgcctgataa gcgtgaggtc ggtggttcga
      181 gtccactcgt gcccattaat tggagaatta ctcaagaggc tgaagaggac ggtttgctaa
      241 atcgttaggt cgggtaactg gcgcaagggt tcgaatccct tattctccgt tttaatgaga
      301 gtttgtaact ctctttttta tttttagaga caataaagct tcagatccgt aaaacttaat
      361 tgaattacta atctgaagtt atttttatgg ctctttgtca actgtagtgg gttgaagaaa
      421 agctaagctc gagaaaggac aaatttcgtc ctttcttttt tgatgttcaa agcgataaaa
      481 atccgttttt taaagttttc aaagtttcga aaaccaaagg cattgcactt gataagtttg
      541 atgagattat tggtcgcttc cagtttggcg ttagaatagt gtagttgaag ggcgttgaca
      601 atcttttctt tatctttgag gaaggtttta aagacagtct gaaaaatagg atgaacctgc
      661 ttaagattgt cctcaataag tccgaaaaat ttctctggtt cctttttctt cattagactt
      721 ccacaatcag ggcaagatgg agcctcataa tccagcttag cgataatttc tttgtgggta
      781 tccatattga tgatatctag aatcttgatg tttgggtctt taatgtctag taattttgtg
      841 ataaaatgta attgttccat atgattcttt ctaatgagtt gttttgtcgc ttttcattat
      901 aggtcatatg ggactttttt tctacacaaa ataggctcca taatatccat agggaattta
      961 cccactacaa atattataga gcccgtttta atgagagttt gtaactctct tttttgtttt
     1021 tagagacaat aaaacttcag atccgtaaaa cttaattgaa ttactaatct gaagttattt
     1081 ttatatcgtt tatattataa ttgtgttatt ttacttccaa ctattgagag aaatttcgcc
     1141 actatttagc cagatttctt ttccgttatc acattgaact aaaagttttc cattttctga
     1201 gatgtcttta gcaagtccct tgtagtcttt ttgctctagt gtgaaagtga cttcttttcc
     1261 tagaatgaat gactgttttt tgtataggta taatagctct tctgctggtg tttcgaagaa
     1321 agcacgccag atttctatga tcaattcatt ccttgttata ggagctgtag ctttaaataa
     1381 gctggcagct ttttctttta attcctgagg gaagtcttta atagtgaaat tgatacctac
     1441 tccaataatg atatctgtga ctaagccagt ttctacagag gtcattgctt cagtaaggat
     1501 tcctccaatt ttatgattgt ttagatagat atcattgacc cattttatgt cgacatctat
     1561 taaagttagg ttcttaatgg ctttgtagac agctccagct acaagtagtg tgtaggatgg
     1621 taatttgtca taggggagat ttggtttaag atggagtgtc atataaatac caccttgtgg
     1681 tgagtagaag gaacgttgaa aacggcctcg gcctgctgtt tgataggaag ctagatagag
     1741 ggtatttgct tcatggccta aatcaattgc ttcttttgca tctagttgtg ttgattttgt
     1801 ttcgggttta aagctgactt taattggaag attttcttct agaatctctg gaagaataag
     1861 gtcaccattc atcagtttat atcctctatt tttgatacta tcaatttcaa tgccttcttg
     1921 ttctagtcgc ttgatggctt tccaaattgc tgttcggctt agggatagtt tttctgcgat
     1981 tttttctccg ctgatatagt cggtttcttt agataggatt tggtagacag cttggtagga
     2041 tttcataatg ttgcctttct cactagttgg tattgagagt attcttttct tgtatgactt
     2101 ggagtctgat taaagtattg tttataagct ttcgaaaaat ggagtggatc tgaaaaacct
     2161 accgagtatg caattacctt gatggactct tgggtatttt cgagaagttg tctagctcgg
     2221 tgcattcgaa cgtagagtag gtattctttg ggtgataagg tattaaattc tttgaatacg
     2281 cttgataagt agcttctgtg aacggatagt tcttttgcta aatcttgaat tgtaagtgat
     2341 tgaggatagt ggctatcaat taatcgtttg cattcaagat agagttggtg ggttgatgaa
     2401 atattctttt ttttctgatt gggagcaata gttcccagat gaaacatcag ttcatgaagt
     2461 tgtcccatga tatggagttg agctaattca cttgattttg taatctgagc gaagcggaca
     2521 atgtctgaga tgagttttgc agtagtctgg gtatgacaag tttcagattg gatgagatag
     2581 gattgatcag aaatttgaga aagagcaaaa taatcagggg atttccctcc agtgattcct
     2641 aaccagtagt aggcccaagg ttctttacta tctgcttgat aaaaggttag ttcctctggt
     2701 tttaatagaa agaaatctcc ttcttttaaa tcaacaattt tacccttgta ataaaatttt
     2761 ccttgtcctt tagtaatgta atgtagaacg tatgtatcac gaatggctgg accaaaagag
     2821 taattaggtg tgcattcctc atatccataa aagcttaggg caaggtcgat tgttccagtc
     2881 tggtattctg aaaaaactaa catgtgctac ctcctaccta acattttacc atattcttga
     2941 gacatttttc tattttggaa agcgatttca ggtgataaaa tataatcaat aaagtgatga
     3001 ggtgaagtaa atgggagtta ggatagagaa taatctattt tatgttgaga gtaaaaatct
     3061 aagtttgatt attgaaaatc gaaatggcta cttacttttg aaacatttag gaaagactat
     3121 taagaactat aaaggttcca atagtgttta tgaacgagac catgcctttt caggaaatcc
     3181 aacggctact aatcgaacct ttagtttaga tactcagcga cagatttttg gacaacatgg
     3241 cttaggagat tttaggaaac caactataca ggttcagcat agtgtaactg aagtaacaga
     3301 ctttcgattt gtagaagcaa agattttaaa aggtcagaat ggtccacagg gcttaccttc
     3361 tccacatagc atggacgata cagagactct tgtcttaatg ttagaagatt ctaaggctca
     3421 acttagtctg actttgtatt atactacttt taataatgat gcgactatta ctagctacag
     3481 taaattagat aataatagta atcaggaagt tgtcatccat aaagattttt cttttatggc
     3541 tgattttcca gctgcagatt acgaaatagc aactctgcag ggtgcttatg ctcgtgaaaa
     3601 gactgttaga cgtcaacagg tagaacaagg aatcttttcg attagttcaa accgaggtgc
     3661 ttctggtcat gctcaaacac cagctcttct actatgcgaa caaggagtca cagaggatgc
     3721 tgggaatgtg tttgctattc aactaatgta tagtggcaac tttgaagctt ttgttcaaaa
     3781 aaatcaattg aatgaagttc gggtggctat tggcattaat ccagaaaact tttcttggaa
     3841 gttagcccct gaggaatact ttgaaacacc ggtagcttta gtgactcatt cagatcaggg
     3901 attaactggt attagtcatg aaagtcagaa ttttgtactg aagcacatta ttctaagtga
     3961 attttctaaa aaagaacgtc caattctaat caataactgg gaagctactt actttgactt
     4021 tcagagagaa aaactgttag agttagcaga tgaagctaag aaagttggca ttgaactttt
     4081 tgtattagat gatggttggt ttggcaatcg ttttgatgat aatcgtgctt taggtgattg
     4141 ggttgttaat gaggaaaaac tgggtggaag tctagaaagt ctgatttcag ctatccatga
     4201 aagaggtttg cagtttggac tttggttaga acccgaaatg atttctgtag atagtgattt
     4261 gtatcgtcaa caccctgact gggctattca ggttcctgac tatgagcata cttattctcg
     4321 gaatcaatta gtacttaatc ttgccaatcc tcaggtagta gaatacttga aaagtgtctt
     4381 agatcaactc ctatcttatc atgagattga ttacattaaa tgggatatga accgcaatat
     4441 cactaagcta gggaatggat taacttatct agagacacag atgcaatctc atcagtacat
     4501 gctggggctt tatgaactcg tttcttatct gacagagaag cacagccata ttctctttga
     4561 gtcctgctct ggtggtggtg gacgaaatga tcttggtatg atacgctatt tcccacaagt
     4621 ctgggctagt gataatactg atgccattgc acgtttacca attcaatacg gttcatccta
     4681 tttctatcca accatttcta tgggggctca tgtgtcagca gtaccgaatc atcagatggg
     4741 acgaatgaca ccattagaaa cacgtggcca tgtagcaatg atgggaaatt tgggctatga
     4801 gcttgatttg acaaatttat cagatgaaga gaaagctacg attgctaatc aggtgaactt
     4861 gtataaagaa ttacgaccag tagttcagtt aggacagcag tatagactaa ttaatcctga
     4921 tactgcatcc aatgaagcag ctgtacaatt taattacgga aatcaaacga ttgtaaccta
     4981 cgttcgcgtt ttatctgttg tagagaccat ggaaacaact ttaaaattaa aagatttgga
     5041 tgaagaggga ctatataaat tacaggaaaa tggcgaagtt tactcaggtg cagaactaat
     5101 gtatgcgggc ttaactgtta tcttatccca aggagatttt ttgagtagac agtatatttt
     5161 tagaaaacta tgatatgtac tgaccccaaa agttagattt attctatcta acttttgaag
     5221 tgcagtttga taagggtgta taaatttata aaggaggctt tctaatggaa tggtataaaa
     5281 aaatcggact tcttgcaact acaggtttag ctttgtttgg gctcggtgct tgctccaact
     5341 atggtaaatc tgcggatgac acagtgacca tcgagtattt caaccagaaa aaagaaatga
     5401 ccaaaacctt ggaagaaatc actcgtgatt ttgagaagga aaaccctaag ataaaggtca
     5461 aagtcgtcaa tgtaccaaat gctggtgaag tattgaagac acgcgttctc gcaggagatg
     5521 tgcctgatgt ggtcaatatt tacccacagt ccatcgaact gcaagaatgg gcaaaagcag
     5581 gtgtctttga agatttgagt aacaaagact acctgaaacg cgtgaaaaat ggctacgctg
     5641 aaaaatatgc tgtaaacgaa aaagtttaca acgttccttt tacagctaat gcttatggaa
     5701 tttactacaa caaagataaa ttcgaagaac tgggcttgaa ggttcctgaa acctgggatg
     5761 aatttgaaca gttagtcaaa gatatcgttg ctaaaggaca aacaccattt ggaattgcag
     5821 gtgcagatgc ttggacactc aatggttaca atcaattagc ctttgcgaca gcaacaggtg
     5881 gaggaaaaga agcaaatcaa taccttcgtt attctcaacc aaatgctatt aaattgtcgg
     5941 atccgattat gaaagatgat atcaaggtca tggacatcct tcgcattaat ggctctaagc
     6001 aaaagaactg ggaaggtgct ggctataccg atgttatcgg agccttcgca cgtggggatg
     6061 tcctcatgac accaaatggg tcttgggcga tcacagcgat taatgaacaa aaaccgaact
     6121 ttaagattgg aaccttcatg attccaggaa aagaaaaagg acaaagctta accgttggtg
     6181 cgggagactt ggcatggtct atctcagcca ccaccaaaca tccaaaagaa gccaatgcct
     6241 ttgtggaata tatgacccgt tcagaagtca tgcaaaaata ctacgatgtg gacggatctc
     6301 caacagcgat cgaaggggtc aaacaagcag gagaagattc accgcttgct ggtatgaccg
     6361 aatatgcctt tacggatcgt cacttggtct ggttgcaaca atactggacc agtgaagcag
     6421 acttccatac cttgaccatg aactatgtct tgaccggtga taaacaaggc atggtcaatg
     6481 atttgaatgc cttctttaac ccgatgaaag cggatgtgga ttaggagtag agagactatg
     6541 aaaaaagtat tacaaaaata ttgggcatgg gcttttgtgg tcatccccct cttgttacaa
     6601 gcaattttct tctatgtgcc gatgtttcaa ggagcctttt acagttttac caactggaca
     6661 ggattgactt acaactacaa atttgtcggc ttaaacaact ttaagctcct cttcatggat
     6721 ccaaaattca tgaatgcgat tggctttacc gcaatcatta cgattgccat ggtggttggt
     6781 gagattgcac tcgggatctt cattgcgcgt gtcttgaact ctaaaatcaa aggccaaacc
     6841 ttcttccgtg cttggttctt cttcccagct gttttatctg gtttgacagt ggctttgatc
     6901 ttcaagcaag tcttcaacta cggtcttcca gcgattggga atgcccttca tattgaattt
     6961 ctccaaacca gtcttttagg gactaagtgg ggagcaatct ttgcggctgt ctttgtcctt
     7021 ctttggcaag gggtggctat gcccatcatc atcttcctag ctggtttgca atctattcca
     7081 actgagatta cagaggcagc aaggattgat ggtgcgacta gcaagcaagt tttctggaac
     7141 attgaattgc cttacttgct accaagtgtc tctatagtct ttatcctagc cctaaaaggt
     7201 gggctgactg cctttgacca agtctttgcc atgaccggtg gtggtccaaa caatgccaca
     7261 acctcacttg ggctcttggt ttataactat gcctttaaaa acaaccaatt cggttatgcc
     7321 aatgccattg ccgtaatctt gttcttctta attgtagtga tttcgatcat ccaattgaga
     7381 gtatctaaga aatttgaaat ttaagaggag aagcatgatg aaacaagatg aaagaaaagc
     7441 cctgattggc aaatacattc tattgattct aggatcggtt ctgattttag tgccgctcct
     7501 tgctaccctc tttagttcct tcaaatccac taaggatatt gtagataatt tctttggctt
     7561 tccaaccaac ttcacatggg acaactttag ccgtctctta gctgatggga ttggaggcta
     7621 ttattggaac tctgtcgtca tcactgtctt gtctttactt gcagtaatga tctttatccc
     7681 tatggcagcc tactccatcg ctcgcaatat gagtaaaaga aaagccttta ccatcatgta
     7741 taccctctta atcctcggaa tcttcgtacc tttccaagtc atcatgattc cgattacggt
     7801 tatgatgagt aaactcggtt tggctaatac ctttggtttg atcttgctct acttgaccta
     7861 tgcgattcca cagaccctct ttctctatgt tggctatatc aaaatctcga ttccagaaag
     7921 tctggatgaa gcagcagaga tcgatggggc taatcaattt acaacctatt tccgcatcat
     7981 cttcccaatg atgaaaccga tgcatgcgac aaccatgatc atcaatgccc tttggttctg
     8041 gaatgacttc atgttgccac tccttgtctt gaaccgggat tccaaaatgt ggactctgcc
     8101 tttgttccaa tacaactacg caggccaata tttcaacgac tacggaccaa gctttgcctc
     8161 ttacgtggtc ggcattatca gtatcaccat tgtctatctc ttcttccaac gccatatcat
     8221 cgcaggaata agcaacgggg cagtgaagta atactcaatg aaaatcaaag agcaaactag
     8281 gaagctagcc gcaggttgct caaaacactg ttttgaggtt gtggatgaaa ctgacgaagt
     8341 cagtaaccat atctacggta aggcgacact gacgtggttt gaagagattt tcgaagagta
     8401 taacatgaat ttgatttacg aagccagatc atatgagact tggcttcaat tagaaaaagg
     8461 agagtaatga tgccaattca aaataaaacc atgttgatta cctattctga tagccttgga
     8521 aataatctta aagacttata tgataatttg gaagagcatt ttggagatgc tattggagga
     8581 gttcaccttt taccattttt cccatcaaca ggtgatcgtg gatttgcgcc agttgactac
     8641 gacgaagtgg actcagcttt tggtgattgg gaggatgtta agcgtttagg tgagaaatat
     8701 tatcttatgt ttgattttat gattaatcat atttctcgtc aatccaagta ttataaggac
     8761 tatcaagaaa aacatgaagc cagtgaattt aaagatctct ttttaaactg ggataagttt
     8821 tggccagaaa accgtccgac acagtctgat gtagatttaa tttacaagcg taaggatcgt
     8881 gcaccaaagc aagagattgt gtttgaagat ggttcagtgg aacatttgtg gaataccttt
     8941 ggtgaggagc agattgatct tgatgtgacc aaagaagtaa ctatggaatt tatccgtaag
     9001 accattcagc acttggcaag taatgggtgt gatttgattc gtctagatgc ctttgcttat
     9061 gcagtgaaga aattggatac taatgatttc tttgtggaac cagatatttg ggatttattg
     9121 gacaaagttc gagatatcgc tgctgagtat gggacagaga ttttacctga gattcatgaa
     9181 cactattcga ttcagtttaa aatagcagac catgattact atgtttatga ttttactctt
     9241 ccaatggtga cactttatac tctttacagt tccagaacag agcgtttggc taagtggttg
     9301 aagatgagcc cgatgaagca atttacgacg ctagataccc atgatgggat tggagtagta
     9361 gatgtcaagg atatcctgac cgatgaggag attgactatg cttcaaatga actctataag
     9421 gttggagcca atgtcaaacg taagtactct agtgccgagt ataacaactt agatatctac
     9481 caaatcaatt caacctacta ttcagcgctt ggagatgatg atgtcaagta ttttctcgct
     9541 cgtctaattc aagcttttgc cccaggtatt cctcaggttt actatgtggg tctattagca
     9601 ggcaagaatg acttgaaatt attagaagaa actaaagaag gtcgaaatat taatcgtcat
     9661 tactatagca acgaggaaat agcaagagaa gtgcaacgac ctgttgtgaa ggcccttctc
     9721 aatctatttt ctttccgtaa ccgttcagaa gcctttgatc tagaagggac tactgagata
     9781 gagacaccaa cagctcacag cattgtaatc aaacgtcaaa ataaagataa gtccgtaaca
     9841 gcagtagcag aaattgattt gcaaaatcag acttatcggg taattgagaa tggagttgaa
     9901 gtatcatttt gaagccttga tatggtggat aaaatagggt ttttattttg gaaaacgttt
     9961 cctttgtttt caaattgcta aaaaagtggt acaatatagg atagcttact attatctgaa
    10021 tcagctgatt tggagagaaa ggattcattt tgaaatcaat aggctttatt gaaaagctga
    10081 aggggttgtc tagtaaagag ctgattttat tgggaattat cctaagtatc tttttaccct
    10141 tttatctttt tgtagttgta ctctgtttat atattatcag tttgattttt acaggagaca
    10201 tgaaaagtat tcttcagaaa atgggggagc atccgatgct gcttcttttt cttagctata
    10261 gtactgttat atccattctt gcacaaaatt ggatgggtct tgtggcttca gtaggaatgt
    10321 ttctatttac tattttcttt ttgcactatc agtcgatttt atcccataaa ttctttcgat
    10381 tgattttgca gttcgtcttg tttggtagtg tcttgtcagc tgcttttgcc agtttagaac
    10441 atttccaaat tgtgaagaaa tttaactatg cttttctttc acccaatatg caggtgtggc
    10501 atcagaaccg ggcagaagtg accttcttta atcctaatta ttatggaatt atttgttgtt
    10561 tctgtattat gattgctttc tatctgttta caacgaccaa gttgaattgg ttgaaagtat
    10621 tctgtgtgat tgcaggcttt gttaatctct ttggtttgaa ctttactcaa aatcgaactg
    10681 cctttcctgc tattatcgct ggagcaatta tctatctctt tacgactatt aaaaactgga
    10741 aggccttttg gcttagtatt ggggtcttcg cgattggttt gagtttcctc ttttctagtg
    10801 atttgggagt tcgaatgggt actttagact cttctatgga agaacgcatt tctatctggg
    10861 atgctgggat ggccttgttt aagcaaaatc ctttttgggg tgaagggcca ttgacctata
    10921 tgcactctta tcctcggata catgctcctt atcatgaaca tgcccacagt ctttatattg
    10981 atacgattct gagttacgga attgtgggta ccattttatt agttttgtct tctgttgctc
    11041 ctgttcgctt gatgatggat atgagtcagg agtcggggaa acgtccgatt atcggccttt
    11101 atctatcttt ccttacagtg gttgctgtgc acggaatttt tgacttggct ctcttctgga
    11161 ttcagtcagg ctttattttc ttgctagtta tgtgcagtat tccattggag catcgaatgt
    11221 tggtatcgga catgacggat taagttttat aagtttgaaa tcttctacct tgggtaggag
    11281 atttttttat acgatgggca tgtcgtgcat ctgaggtgta agtcctctgt agggatccac
    11341 taccggtgaa tacaatagcg ctccccaagc ctgactatcg tgaggtagcg gattaaaatg
    11401 gtctggggat agatcgtttt aagtctgacg caggaaataa gaattgtcag agaaagcaat
    11461 agtgaaatcg taggctatga atagaaacgt gatagcgagg agcatatagt ggataaggta
    11521 gcgagaaatt ttaaagtata aaagatagtc ttaatctata tatgtaaatc acaaaagtaa
    11581 ttgaattcgg aataaggttg gtgtgaaaag acatagtaaa ctgaatcttg aatactagaa
    11641 tgatacttct acaatattgt tataatttaa tttgaattcc aaaatcacat tgttccgtcc
    11701 gtatttcatt ttactgtatg tcttcctaaa ctccaaagtt tctgcgtcaa atttcctatt
    11761 ttcactgtag tctttgacac ttcgaacgac aatttgaatc atatattcaa aaaaaaatga
    11821 aaaatttgtg ccaacaagcc taaatattct gaaaatttgt ttgattttta atggataatg
    11881 tgatataatg gttgtcaatc tataattcac ataaacagag gagtagaaaa tgaaaaaaaa
    11941 tcgtgtattt gctacagcag gtcttgtttt attagcagca ggtgtacttg cagcatgcag
    12001 ttcttcaaaa tcatctgatt catcagcccc taaagcttat ggctatgttt atacagcaga
    12061 cccagaaacc ttggactacc tgatttcaag taaaaatagt acaacagtag tgacttcaaa
    12121 tgggattgat ggtttattca ctaacgataa ttacggtaat cttgctcctg cagttgcaga
    12181 ggattgggaa gtctctaagg atggtttgac ctacacttat aagattcgta aaggggttaa
    12241 atggtttacc tctgatggag aagaatatgc agaggtgacg gctaaagatt tcgtgaacgg
    12301 tttaaaacac gcagcagata aaaaatcaga agctatgtat ttagctgaaa attcggttaa
    12361 aggcttggca gattatctat caggaacttc aacagatttt tcaacagttg gtgtcaaggc
    12421 ggttgatgat tatacgttac aatacacttt gaaccagcct gaaccgttct ggaactctaa
    12481 gttgacctat tctattttct ggcctctgaa tgaagaattc gaaacatcaa aaggaagcga
    12541 ttttgctaaa ccaacagatc cgacatcctt gctttataat ggtccattct tgttgaaagg
    12601 gttgactgca aaatcttctg tagagtttgt aaaaaatgag caatattggg ataaagaaaa
    12661 tgtccaccta gatactatca atctagctta ctatgatgga tcagatcagg agtcgctaga
    12721 gcgtaacttc actagtggag cttatagtta tgcccgtctt taccctacca gctccaacta
    12781 ttctaaggtt gcagaagaat acaaggacaa tatctattac acacaatcag gctctgggat
    12841 tgctggtctg ggtgtgaata ttgatcgcca aagttacaac tatacttcta aaactacaga
    12901 ttcagagaaa gtagctacta agaaggcatt gcttaacaaa gatttccgtc aagccttgaa
    12961 ttttgctctt gatcgctcag cttactcagc tcaaatcaat ggtaaagatg gagcagcttt
    13021 agcagttcgt aatttatttg taaaaccaga ctttgtttca gctggtgaga agacctttgg
    13081 tgatttagtc gctgctcaac ttcctgctta tggtgatgag tggaaaggtg tgaatttagc
    13141 tgatgggcag gatggtttat tcaatgctga caaggccaag gcagagtttg cgaaagctaa
    13201 gaaagcttta gaagcagacg gcgttcagtt tcctattcat ctggacgttc cagtagacca
    13261 agcatcaaaa aactacatat ctcgtattca gtcctttaaa caatctgtag aaacagttct
    13321 tggtgttgaa aatgtcgttg ttgatattca acaaatgaca agtgatgaat tccttaatat
    13381 tacttactat gctgccaatg cttcatctga ggattgggat gtatcgggag gagtttcatg
    13441 ggggccagac tatcaagacc catctactta cctggatatt ttaaaaacaa ctagcagtga
    13501 aactacaaaa acatatttag gatttgataa tccaaatagc ccttcagtag ttcaagttgg
    13561 tttgaaagaa tacgataaat tagttgatga agctgccaaa gagacaagcg acttgaatgt
    13621 ccgttatgaa aaatatgcag cggctcaagc atggttgaca gatagttcac tctttattcc
    13681 tgctatggct tcttctggtg cagcaccagt gctttcacga attgttccat ttactggagc
    13741 ttctgcgcaa acaggctcta aggggtcaga tgtttacttc aaatatttga aattacaaga
    13801 taaagtggtg actaaggaag agtatgaaaa agctcgtgaa aaatggttga aagaaaaagc
    13861 tgaatcaaat gagaaagctc aaaaagaatt ggcaagtcat gtgaagtaaa taatttctaa
    13921 tagaactttc tctccatgag gagaaggttc ttttgggatt tttaaaggaa ataatatgaa
    13981 aaaatatatt tttatgcgtg ttttgcggtc attggtttcg attttcttag taacgacttt
    14041 gacctacacg attatctata ccttggttcc tcgaaaattg attttcaagc aggatcctaa
    14101 ctataataaa attgcaacaa cggctgataa acgtgataac tatgaaaata ctgtgtttga
    14161 gcgtatgggc tacattgagt attacgatac taaagagttg caagaaaagg caagtagcat
    14221 ggattcttct gtaacagtag aagcaaatgc gaccaataaa gctatttatg aaaagtacat
    14281 caatcaatta ggtcatggtt ggactttggg agaatttact gaaagtggtc aattctatgc
    14341 tactcgtgaa attccaattt ttgaacgtgt ttttcacttc tatgctaact tgattgacat
    14401 tgaccataca aataaaatcc aagaccctga aaatccagac ttgaaacgct accttcgttt
    14461 tgaaaatgat ccagctatcg gatggtcatt ggtcggttca ggaactaaac ataaatatct
    14521 cttgtacttt aacagtcagt tcccatttgt tcatcaaaac tttgtgaact tgaatttagg
    14581 tgactcttac ccaacctatg ctaatacacc agttcttcag gttattactc aaggtcaagg
    14641 acaaaccaaa actgcccaag ttcagttccc aacaggtaag aaaacgtctt ctgtaaatat
    14701 ttactcaaga acctacaagt cacctagtca ggctgactct cgtgaagtag ctagctatgg
    14761 gaaagatgat ccttatacag cgactgaaag taattaccaa tatccatcta tgattgtcag
    14821 ctctgctatt actggttcga ttgattggat catctattgc ccttccagat tcattcccta
    14881 tcttgggagc tggagattgg cgttcttacg ttttaccagc agtcatcctt ggtttgttgg
    14941 gtgctcctgg tacagccatt tggattcgtc gttacatgat tgacttgcaa tctcaagact
    15001 ttgttcgttt cgctcgtgca aaaggtttgt ctgaaaaaga aatttcaaac aaacacatct
    15061 ttaaaaatgc catggttccg ctggtttcag gaattcctgg tgccatcatt ggggttatcg
    15121 gtggtgcaac ccttactgaa acagtcttcg ccttcccagg tatgggtaaa atgttgattg
    15181 actctgtaaa agcatctaat aactctatgg tcgttggtct tgtcttcatc tttacatgta
    15241 tttctatctt ctcacgtctt ttgggagata tttggatgac tattattgac ccacgtatta
    15301 aattgactga gaaaggaggc aaataatgtc tacaatcgat aaagaaaaat ttcagtttgt
    15361 aaaacgtgac gattttgcct ctgaaactat tgatgcgcca gcatattctt actggaaatc
    15421 agtgtttaaa caatttatga agaaaaaatc aactgtagtc atgttgggaa tcttggtagc
    15481 catcattttg ataagtttca tctacccaat gttttctaag tttgatttca atgatgtcag
    15541 caaggtaaac gactttagta ttcgttatat caagccaaat gcggagcatt ggttcggtac
    15601 tgacagtaac ggtaaatcgc tctttgacgg tgtctggttc ggagctcgta actccatcct
    15661 catttctgtg attgcgacag tgattaactt ggttatcggt gtttttgtcg gtggtatttg
    15721 gggtatttca aaatcagttg accgtgtcat gatggaagtt tacaacgtca tctcaaacat
    15781 cccacctctt ttgattgtta ttgtcttgac ttactcaatc ggagctggat tctggaatct
    15841 gatttttgcc atgagcgtaa caacatggat tggtatcgcc ttcatgatcc gtgtgcaaat
    15901 cttgcgctat cgtgacttgg aatacaactt ggcatcacgt actttgggaa caccaacctt
    15961 gaagattgtt gccaaaaata tcatgcctca attggtatct gttattgtga caaccatgac
    16021 tcaaatgctt ccaagcttta tctcatacga agccttcttg tctttcttcg gtcttggatt
    16081 accgattaca gtgccaagtt tgggtcgttt gatttcggat tattcacaaa acgtaacaac
    16141 caatgcttac ttgttctgga ttccattgac aacccttgtc ttggtatcct tgtccctttt
    16201 cgtagttggt caaaacttag cggatgctag tgatccacgt acacatagat aggagtagaa
    16261 atgacaaaag aaaaaaatgt aattttgact gctcgcgata ttgtcgtgga atttgacgtt
    16321 cgtgacaaag tattgacagc cattcgcggc gtttcccttg aactcgttga aggagaagta
    16381 ttagccttgg taggtgagtc aggatcaggt aaatctgttt tgacaaagac cttcacaggt
    16441 atgctcgaag aaaatggtcg cattgcccaa ggtagtattg actaccgtgg tcaggatttg
    16501 acagctttat cttctcacaa ggattgggaa caaattcgtg gtgctaagat tgcgactatc
    16561 ttccaggacc caatgactag tttggacccc attaaaacaa ttggtagtca gattacagaa
    16621 gttattgtaa aacaccaagg aaaaacagct aaagaagcga aagaattggc cattgactac
    16681 atgaataagg ttggcattcc agacgcagat agacgtttta atgaataccc attccaatat
    16741 tctggaggaa tgcgtcaacg tatcgttatt gctattgccc ttgcctgccg acctgatgtc
    16801 ttgatctgtg atgagccaac aactgccttg gatgtaacta ttcaagctca gattattgat
    16861 ttgctaaaat ctttacaaaa cgagtatcat ttcacaacaa tctttattac ccacgacctt
    16921 ggtgtggtgg caagtattgc ggataaggta gcggttatgt atgcaggaga aatcgttgag
    16981 tatggaacgg ttgaggaagt cttctatgac cctcgccatc catatacatg gagtctcttg
    17041 tctagcttgc ctcagcttgc tgatgataaa ggggatcttt actcaatccc aggaacacct
    17101 ccgtcacttt atactgacct gaaaggggat gcttttgcct tgcgttctga ctacgcaatg
    17161 cagattgact tcgaacaaaa agctcctcaa ttctcagtat cagagacaca ttgggctaaa
    17221 acttggcttc ttcatgagga tgctccaaaa gtagaaaaac cagctgtgat tgcaaatctc
    17281 catgataaga ttcgtgaaaa aatgggattt gcccatctgg ctgactagga ggaaggaaat
    17341 gtctgaaaaa ttagtagaaa tcaaagattt agaaatttcc ttcggtgaag gaagtaagaa
    17401 gtttgtcgcg gttaaaaatg ctaacttctt tatcaacaag ggagaaactt tctcgcttgt
    17461 aggtgagtcc ggtagtggga aaacaactat tggtcgtgct atcatcggtc taaatgatac
    17521 aagtaatgga gatatcattt ttgatggtca aaagattaat ggtaagaaat cgcgtgaaca
    17581 agctgcggaa ttgattcgtc gaatccagat gattttccaa gaccctgctg caagtttgaa
    17641 tgaacgtgcg actgttgatt atattatttc tgaaggtctt tacaatcacc gtttatttaa
    17701 ggatgaagaa gaacgtaaag agaaagttca aaatattatc cgtgaagtag gtcttcttgc
    17761 tgagcacttg actcgttacc ctcatgaatt ctcaggcggt caacgtcaac gtatcggtat
    17821 tgcccgtgcc ttggtcatgc aaccagactt tgttattgca gatgagccaa tttcagcctt
    17881 ggacgtttct gtacgtgccc aagtcttgaa cttgctcaaa aaattccaaa aagagctcgg
    17941 cctgacctat ctcttcatcg cccatgactt gtcggttgtt cgctttattt cagatcgtat
    18001 cgcagttatt tacaagggtg ttattgtaga ggttgcagaa acagaagaat tgtttaacaa
    18061 tccaattcac ccatatactc aagccttgct ttcagcggta ccaatcccag atccaatctt
    18121 ggaacgtaag aaggtcttga aggtttacga cccaagtcaa cacgactatg agactgataa
    18181 gccatctatg gtagaaatcc gtccaggtca ctatgtttgg gcgaaccaag ccgaattggc
    18241 acgttatcaa aaaggactaa actaataatg gttttataat ttccatgtca atttttatgg
    18301 gaattataaa acttttttgt tggactgatt tgaaaaactt tgaaagcttc ctgaaaga
//
LOCUS       DAVBBO010000046        17721 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ST1
            SAMEA2066453-rid20184263.denovo.046, whole genome shotgun sequence.
ACCESSION   DAVBBO010000046 DAVBBO010000000
VERSION     DAVBBO010000046.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2066453
            Sequence Read Archive: ERR351777
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 17721)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 17721)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980402.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980402.1
            Genome Coverage       :: 176x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:17:33
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,141
            CDSs (total)                      :: 2,104
            Genes (coding)                    :: 1,953
            CDSs (with protein)               :: 1,953
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 16S)
            partial rRNAs                     :: 1 (23S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 151
            CDSs (without protein)            :: 151
            Pseudo Genes (ambiguous residues) :: 0 of 151
            Pseudo Genes (frameshifted)       :: 73 of 151
            Pseudo Genes (incomplete)         :: 76 of 151
            Pseudo Genes (internal stop)      :: 40 of 151
            Pseudo Genes (multiple problems)  :: 32 of 151
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..17721
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2066453-rid20184263.denovo.046"
                     /strain="ST1"
                     /db_xref="taxon:1313"
     gene            complement(<1..224)
                     /locus_tag="VQU30_001576"
     CDS             complement(<1..224)
                     /locus_tag="VQU30_001576"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001050284.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TRAM domain-containing protein"
                     /protein_id="HET2447653.1"
                     /translation="MNLKVKQKIPLKIKRMGINGEGIGFYQKTLVFVPGALKGEDIYC
                     QITSIRRNFVEAKLLKVNKKSKFRIVPSCT"
     gene            262..1038
                     /gene="recX"
                     /locus_tag="VQU30_001577"
     CDS             262..1038
                     /gene="recX"
                     /locus_tag="VQU30_001577"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000705102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombination regulator RecX"
                     /protein_id="HET2447654.1"
                     /translation="MKITKLEKKKRLYLMELDNGDKCYITEDTIVRFMLSRDKVISEE
                     ELKEIQDFAQFSYGKNLALYHLSFKARTEKEVREYLKKYDIDKNIVSQVIANLKEDKW
                     INDGQYAYAIINANQLSGDKGPYVLTQKLAQKGISKSTIEEILNDFDFSEVAQRVANK
                     LLKKYEGKLPARALQDKIIQNLTNKGFSYFDAKIAFDELDSQVDEETTQELIFKELDK
                     QYTKYARKYEGYKLKQRLTQVLARKGYDFSDIASALREYL"
     gene            1127..1660
                     /locus_tag="VQU30_001578"
     CDS             1127..1660
                     /locus_tag="VQU30_001578"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000775318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF402 domain-containing protein"
                     /protein_id="HET2447655.1"
                     /translation="MKLPKEGDFITIQSYKHDGSLHRTWRDTMVLKTTENAIIGVNDH
                     TLVTESDGRRWVTREPAIVYFHKKYWFNIIAMIRDNGTSYYCNMASPYYLDEEALKYI
                     DYDLDVKIFTDGEKRLLDVEEYERHKRKMNYSDDLDYILKEHVKILVDWINNGRGPFS
                     EAYVNIWYKRYVELKNR"
     gene            complement(2100..2856)
                     /locus_tag="VQU30_001579"
                     /pseudo
     CDS             complement(2100..2856)
                     /locus_tag="VQU30_001579"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000567550.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="epoxyqueuosine reductase QueH"
     gene            complement(2994..4616)
                     /gene="groL"
                     /locus_tag="VQU30_001580"
     CDS             complement(2994..4616)
                     /gene="groL"
                     /locus_tag="VQU30_001580"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018166362.1"
                     /note="60 kDa chaperone family; promotes refolding of
                     misfolded polypeptides especially under stressful
                     conditions; forms two stacked rings of heptamers to form a
                     barrel-shaped 14mer; ends can be capped by GroES;
                     misfolded proteins enter the barrel where they are
                     refolded when GroES binds; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chaperonin GroEL"
                     /protein_id="HET2447656.1"
                     /translation="MSKEIKFSSDARSAMVRGVDILADTVKVTLGPKGRNVVLEKSFG
                     SPLITNDGVTIAKEIELEDHFENMGAKLVSEVASKTNDIAGDGTTTATVLTQAIVREG
                     IKNVTAGANPIGIRRGIETAVAAAVEALKNNAIPVANKEAIAQVAAVSSRSEKVGEYI
                     SEAMEKVGKDGVITIEESRGMETELEVVEGMQFDRGYLSQYMVTDSEKMVADLENPYI
                     LITDKKISNIQEILPLLESILQSNRPLLIIADDVDGEALPTLVLNKIRGTFNVVAVKA
                     PGFGDRRKAMLEDIAILTGGTVITEDLGLELKDATIEALGQAARVTVDKDSTVIVEGA
                     GNPEAISHRVAVIKSQIETTTSEFDREKLQERLAKLSGGVAVIKVGAATETELKEMKL
                     RIEDALNATRAAVEEGIVAGGGTALANVIPAVATLELTGDEATGRNIVLRALEEPVRQ
                     IAHNAGFEGSIVIDRLKNAELGIGFNAATGEWVNMIDQGIIDPVKVSRSALQNAASVA
                     SLILTTEAVVANKPEPVAPAPAMDPSMMGGMM"
     gene            complement(4632..4916)
                     /gene="groES"
                     /locus_tag="VQU30_001581"
     CDS             complement(4632..4916)
                     /gene="groES"
                     /locus_tag="VQU30_001581"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730535.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="co-chaperone GroES"
                     /protein_id="HET2447657.1"
                     /translation="MLKPLGDRVVLKIEEKEQTVGGFVLAGSAQEKTKTAQVVATGQG
                     VRTLNGDLVAPSVKTGDRVLVEAHAGLDVKDGDEKYIIVGEANILAIIEE"
     gene            complement(5186..5581)
                     /locus_tag="VQU30_001582"
     CDS             complement(5186..5581)
                     /locus_tag="VQU30_001582"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000282444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
                     /protein_id="HET2447658.1"
                     /translation="MYNKVIMIGRLTSTPELHKTNNDKSVARATIAVNRRYKDQNGER
                     EADFVNMVLWGRLAETLASYATKGSLISVDGELRTRRFEKNGQMNYVTEVLVTGFQLL
                     ESRAQRAMRENNAGQDLADLVLEEEELPF"
     gene            complement(5659..6420)
                     /locus_tag="VQU30_001583"
     CDS             complement(5659..6420)
                     /locus_tag="VQU30_001583"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862677.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HET2447659.1"
                     /translation="MAKNVVITGATSGIGEAIARAYLEQGEDVVLTGRRIDRLEILKS
                     EFAVSFPNQTVWTFPLDVTDMVMVKTVCSDILETIGRIDILVNNAGLALDLAPYQDYE
                     ELDMLTMLDTNVKGLMAVTRCFLPAMIKVNQGHIINMGSTAGIYAYAGAAVYSATKAA
                     VKTFSDGLRIDTIATDIKVTTIQPGIVETDFSTVRFHGDKERAASVYQGIEALQAQDI
                     ADTVVYVTSQPRRVQITDMTIMANQQATGFMIHKK"
     gene            complement(6453..7079)
                     /locus_tag="VQU30_001584"
     CDS             complement(6453..7079)
                     /locus_tag="VQU30_001584"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4479 and tRNA-binding domain-containing
                     protein"
                     /protein_id="HET2447660.1"
                     /translation="MIFTYNKEHVSDVLMVIVKNSGDAKLNVERKGKVARVFLKENGE
                     TVAWNIFEVSSLFEIAERGQVFLSDEQVARLNQELQAEGFTEEIVNDKEPKFVVGEIV
                     EMVAHPDSDHLNICQVAVASDKIVQIVAGAPNARVGLKTIVALPGAMMPKGNFIFPGE
                     LRGEKSFGMMCSPRELHLPNAPQKRGVLELSEDQVVGTPFDPAKHWTA"
     gene            complement(7095..7412)
                     /locus_tag="VQU30_001585"
     CDS             complement(7095..7412)
                     /locus_tag="VQU30_001585"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000615765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin family protein"
                     /protein_id="HET2447661.1"
                     /translation="MIQPASLEELASLVEKAGKKVFLFVADWCGDCRYIYPALPEIEE
                     TNPEFTFIRMDRDQYMDLAKLWDVYGIPSLVVLEKDKEIGRFVNRDRKSKEQINDFLA
                     GLK"
     gene            complement(7409..7708)
                     /locus_tag="VQU30_001586"
     CDS             complement(7409..7708)
                     /locus_tag="VQU30_001586"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001013971.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4651 domain-containing protein"
                     /protein_id="HET2447662.1"
                     /translation="MNGMKAKKMWMAGLALLGIGSLALATKKVADDRKLMKTQEELTE
                     IVRDHFSDMGEIATLYVQVYESSLESLVGGVIFEDGRHYTFVYENEDLVYEEEVL"
     gene            complement(7993..8184)
                     /locus_tag="VQU30_001587"
     CDS             complement(7993..8184)
                     /locus_tag="VQU30_001587"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000291825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding protein"
                     /protein_id="HET2447663.1"
                     /translation="MYYSVDDVVSNAFKKRMILDSFFAFNCSGTMKVSTWVYDKGEWY
                     YVSSSGSMIANDWVKDNGK"
     gene            complement(8345..9019)
                     /locus_tag="VQU30_001588"
     CDS             complement(8345..9019)
                     /locus_tag="VQU30_001588"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000725744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2447664.1"
                     /translation="MKKKAFGIVLLVLAAWILLQGNFGIPSLDGKIWPLLGIVFFAYK
                     SIESILRRHLTSAVFTGLLALIIANYAYDLLPVTNHSLIWASILVVLGVGYLTHSSKF
                     WNEKKWWYNGKKTVVTDKEVAFGSGTFYKQDQDLVDDQVEVAFGDAKIYYDNAEMLGD
                     FATLNIEVAFGNATVYVPQHWRVDLKVETSFGAAKADAPVAPTSKTLTIRGDVAFGKL
                     EIVYVK"
     gene            complement(9025..9471)
                     /locus_tag="VQU30_001589"
     CDS             complement(9025..9471)
                     /locus_tag="VQU30_001589"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000776610.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HET2447665.1"
                     /translation="MKLRIEIDGNLEETEIVIKTPTLTDEIADLQRLLQESKAPRLTF
                     YKGTGEYYLDLSEILFFETEGSKIYAHNQKEAYEVRLKLYELESILPRYFNRVSKSTI
                     ANIRQIYSVDKSFSGTGTISFYQTHKEVHVSRHYQSLLKENLRNMR"
     gene            complement(9573..10088)
                     /locus_tag="VQU30_001590"
     CDS             complement(9573..10088)
                     /locus_tag="VQU30_001590"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000800937.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatase PAP2 family protein"
                     /protein_id="HET2447666.1"
                     /translation="MKNYQEWYRNISSRLTSRPILLFLLRSFNRLMTVAMPLVYLILL
                     VTTYLQLGLGQQVGVCVLIPASGFVALSLFRKKINHPRPYETWDICPLLDKDSSGRSM
                     PSRHVFSATIISMACLHASLPIGLVCLIFSALLGLVRVLGGVHYPKDVLVGYACGLVW
                     GFLFFLFLHVS"
     gene            complement(10085..10447)
                     /locus_tag="VQU30_001591"
     CDS             complement(10085..10447)
                     /locus_tag="VQU30_001591"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2200 family protein"
                     /protein_id="HET2447667.1"
                     /translation="MSQKLYNMKFAAVYLALIAKVERKGGKAESVHQVTSWLTGYEVS
                     DVLACLDRDVTYGDFFRQAPYYVPERIAITGKICSVRIEEIDDPLMQEIRRLDKLVDW
                     LAKGKTSQQVLEKYEKHK"
     gene            complement(10513..12372)
                     /locus_tag="VQU30_001592"
                     /pseudo
     CDS             complement(10513..12372)
                     /locus_tag="VQU30_001592"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001850459.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein/permease"
     gene            complement(12389..12859)
                     /locus_tag="VQU30_001593"
     CDS             complement(12389..12859)
                     /locus_tag="VQU30_001593"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000360543.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="winged helix-turn-helix transcriptional
                     regulator"
                     /protein_id="HET2447668.1"
                     /translation="MDKPMLVFKRFGHQIHLMVQKEAKRCGIEFMGGPQGQVVHFLDN
                     REKNQDLVLIKDIEQELNITKSVASNLVKRIVQNGLVELEASPVDKRAKFVRLTDKAR
                     SQMQQVKAFFERIDKQLMEDIDEDELLIFEKVLGQLQANIKGIGGENKEISQKN"
     gene            complement(12983..13699)
                     /locus_tag="VQU30_001594"
     CDS             complement(12983..13699)
                     /locus_tag="VQU30_001594"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015604432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YebC/PmpR family DNA-binding transcriptional
                     regulator"
                     /protein_id="HET2447669.1"
                     /translation="MGRKWANIVAKKTAKDGANSKVYAKFGVEIYVAAKKGDPDPESN
                     SALKFVIDRAKQAQVPKHIIDKAIDKAKGNTDETFTEGRYEGFGPNGSMLIVDTLTSN
                     VNRTAANVRAAFGKNGGNMGASGSVSYLFDNKGVIVFGGEDADAVFEQLLEADVDVDD
                     VEAQEGTITVYTAPTDLHKAIVALRESGIEEFQVTELEMIPQSEVELSGEDLETFEKL
                     YSVLEDDEDVQKIYTNVDGF"
     gene            complement(14580..15989)
                     /gene="ply"
                     /locus_tag="VQU30_001595"
     CDS             complement(14580..15989)
                     /gene="ply"
                     /locus_tag="VQU30_001595"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001284359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cholesterol-dependent cytolysin pneumolysin"
                     /protein_id="HET2447670.1"
                     /translation="MANKAVNDFILAMNYDKKKLLTHQGESIENRFIKEGNQLPDEFV
                     VIERKKRSLSTNTSDISVTATNDSRLYPGALLVVDETLLENNPTLLAVDRAPMTYSID
                     LPGLASSDSFLQVEDPSNSSVRGAVNDLLAKWHQDYGQVNNVPARMQHEKITAHSMEQ
                     LKVKFGSDFEKIGNSLDIDFNSVHSGEKQIQIVNFKQIYYTVSVDAVKNPGDVFQDTV
                     TVEDLRQRGISAERPLVYISSVAYGRQVYLKLETTSKSDEVEAAFESLIKGVAPQTEW
                     KQILDNTEVKAVILGGDPSSGARVVTGKVDMVEDLIQEGSRFTADHPGLPISYTTSFL
                     RDNVVATFQNSTDYVETKVTAYRNGDLLLDHSGAYVAQYYITWDELSYDHQGKEVLTP
                     KAWDRNGQDLTAHFTTSIPLKGNVRNLSVKIRECTGLAWEWWRTVYEKTDLPLVRKRT
                     ISIWGTTLYPQVEDKVEND"
     gene            complement(16000..16332)
                     /locus_tag="VQU30_001596"
     CDS             complement(16000..16332)
                     /locus_tag="VQU30_001596"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812878.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2447671.1"
                     /translation="MYICIDNSMTKNKELVKNQTFKPALLTRRLVKNFMIEEPDLARN
                     PFTRPTLIDLDKVFMLDNTVIPTSYLARRRRNVSEELYEEILDYLVQPRLISLNKSEF
                     MQLNPGTY"
     gene            complement(16403..17011)
                     /locus_tag="VQU30_001597"
     CDS             complement(16403..17011)
                     /locus_tag="VQU30_001597"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000083609.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2447672.1"
                     /translation="MSQSSYLSPLLWLKKEADKEKMSATQCQIFFFYYQMFELLFARE
                     SDMKDLCLGTKGFYFSQLEKNLLSGVSRFLKNLEGKVTLKANQEVSARKALFLALTTS
                     QSDWQELAPVFDFYQTIGRLENPSLLSSQDRQHLMWIYQSALEKDYIVKVIGDKHFVL
                     KRQDATKLTARQTQTLEILSQSEDLVNPVYVTLGEKGVLLLD"
     gene            complement(17024..17482)
                     /locus_tag="VQU30_001598"
     CDS             complement(17024..17482)
                     /locus_tag="VQU30_001598"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000186958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4231 domain-containing protein"
                     /protein_id="HET2447673.1"
                     /translation="MTPEEMYLTERLDVQIAHFLKKSVQHRRRYKVLKITEIVAGFLI
                     AVFCAIPMPGDRYRLISVALSSLGLLCEGIINLYNAKENWISYQKTAQLLEKEKFLYQ
                     CQTEKYAGKTKAFALFVKTCEGLISEEINQWESIQSKEVAASADAPVKKE"
     gene            17607..>17721
                     /locus_tag="VQU30_001599"
     CDS             17607..>17721
                     /locus_tag="VQU30_001599"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS5/IS1182 family transposase"
                     /protein_id="HET2447674.1"
                     /translation="MNYEASKQLTDTRFKRLVGVQRTTFEEMLAVLKTAYQK"
BASE COUNT         5233 a         3942 c         3237 g         5309 t
ORIGIN      
        1 atagtacaag atggcacaat tcgaaattta gacttcttgt tgaccttcag taattttgct
       61 tcaacaaagt tgcgtctaat agaagtaatc tgacaataga tatcttcgcc tttgagagct
      121 cctggtacaa agactaatgt tttttggtaa aagccgattc cctcaccgtt aattcccatg
      181 cgcttgattt ttaatggtat tttttgtttc actttcagat tcatacccct atcttatcac
      241 attttgagtt ataatagagc tatgaaaatc acaaaacttg aaaagaaaaa aagactctat
      301 ctgatggagc ttgataatgg cgacaaatgc tatatcaccg aagatacaat tgttcgtttt
      361 atgttatcga gagataaggt gataagcgaa gaggaattga aagagattca agactttgct
      421 caattttctt atggtaagaa tctggccctc taccacttat cctttaaagc acgcactgaa
      481 aaagaagtca gagaatatct gaaaaaatac gatattgata aaaacatcgt ttctcaagtt
      541 attgctaatc ttaaagaaga taagtggatt aatgatggtc agtacgctta tgctatcatc
      601 aatgccaatc aactttcagg agacaaggga ccttatgtac tgactcagaa attagcacaa
      661 aaaggaattt caaaatctac tatagaagaa atcttgaatg attttgattt ttcggaagtt
      721 gctcaacgtg tagccaataa actattgaaa aaatatgagg gaaaacttcc agctcgtgcc
      781 ctgcaagata agattatcca gaacttgact aacaagggct tctcttattt tgatgctaaa
      841 attgcctttg acgaattgga tagtcaagtt gatgaagaaa cgactcagga actcatcttc
      901 aaggaacttg ataagcaata tactaagtat gcccgaaagt atgaaggata caaactgaag
      961 cagcgtttaa ctcaagtttt agcacgaaag ggctacgatt tttcggatat agcaagcgct
     1021 cttagagaat atctttaata tttccaagtg aaattcacag attttaggta attttatggt
     1081 acaatagtaa atgataaact tataaattgt agaaagttgg ttagttatga agcttccaaa
     1141 agaaggcgac tttattacaa ttcaaagtta taagcatgat gggagtctcc accgaacttg
     1201 gcgggacacc atggtactaa aaacaacaga aaacgccatt attggtgtca acgatcatac
     1261 acttgttacc gaaagtgatg gtcgtcgttg ggtcactcga gaaccggcta ttgtttactt
     1321 tcacaagaaa tattggttta atatcattgc catgattcgt gataatggaa cttcttacta
     1381 ttgcaatatg gctagcccct actatctgga tgaagaagca ctgaagtata ttgattacga
     1441 tttggatgtt aaaattttta cagatgggga aaaacgtctc ttggacgttg aagagtacga
     1501 gcgtcacaaa cgcaaaatga attattctga tgacttggac tatattttaa aagaacatgt
     1561 caaaattctt gttgattgga ttaacaatgg acgtggtcct ttctcagaag cctatgtaaa
     1621 catttggtac aagcgctatg tagaactaaa gaatcggtaa agttgtcaaa ggtcaggaac
     1681 aaaatcctga ccttgttttt ttggtagtat aaaataaatt gtgtaaacac aaaaaggaat
     1741 aaatccatta tagcagagtt acaacacatt tctataaaga aatttattcc tacgactcag
     1801 tttggcatgc ttaacttcct aactcaaaaa caaagcatcg attaatttat ccgttcttct
     1861 tttgaaacag atttgaactg ataattgctc gttttaattt aagaagctct tttgagcaaa
     1921 acttcatttt tttaagagtc caacaatttc tgtctatcgc ttttctacta gcaaaaaacc
     1981 tcccttgagg caagttttca tttatatatc taatttcgta acagtatagt aaaatgaaat
     2041 aaggacagtc aaatcgattt ctaacaatgt tttagaagta gaggtgtact attctagttt
     2101 caatctacta taaatttgat atgagaatag tctttctcaa catccttatc caacaagcat
     2161 gctgtggcgt ccttcttaac ttgaaccagg tcaatattct gggcttgggc tgccatagac
     2221 gcagccacaa taacattgac gatagatatc atactcctca cacatctcta ctgaacgttt
     2281 gtagccttga tttttcttga aatcgttggg aagatagtgg gtcgtgtaaa ttttttgcac
     2341 atcgattccg atgctattga tggtttgaga attcttatga ggactgatgg tcaaggctga
     2401 accaaagtag tcaaagccca agtccatagc cacttgcgct gttttatcca gtcggtagtc
     2461 aaaacaaacc ttgcaacggt cgccaccttc gggctcctcc tctagtcccc taactagttt
     2521 tcggtattaa ttgggttcgt agggagcttc taggtactga accgtatttc ctgtccgatc
     2581 attaaaatca ctaacaaatt tcttgatgac atagacccgc ttatggtatt ctactttggg
     2641 atggatatta gaattggcaa aatagatggt cacatctgca tacttggtca aatattctag
     2701 tgtataggta ctacaagggg cacagcaaac atgcacgaga atggttggcc gctgctcatt
     2761 tttctcccat gcttgtacca ttttctgcat gacacggtca taattaatct tctgattggg
     2821 gggcatcttg cacagaattt cttctacatc gatcatgttc ttctcctttt tctagtctta
     2881 ttttatcata taagttagaa gagctcaaat caatttagaa gtgaatatta taaaaagaag
     2941 ggttagtcat tccctccttt tgtgtttttt ataagttgtt ttctatagaa agcttacatc
     3001 atcccgccca tcatacttgg atccattgct ggagctgggg ctactggttc tggtttattg
     3061 gctacgactg cttctgttgt caaaatcaag ctggctacag atgctgcatt ttgtagggct
     3121 gaacgactca ctttaactgg atcaatgata ccttgatcaa tcatgttaac ccactcgcca
     3181 gttgctgcgt tgaatcctat accaagctca gcatttttca aacgatcgat aacgatagat
     3241 ccttcaaatc ctgcattgtg agcaatttga cgaacgggtt cttccaaagc acggagaaca
     3301 atattacgtc ctgttgcttc atctcctgtc aattccaagg tagcaacagc tggaatcaca
     3361 ttggcaagag ctgttccacc acctgcaaca ataccttctt caacagctgc acgagtagcg
     3421 ttgagggcat cttcaatgcg gagtttcatt tctttcaact cagtttcagt tgcggctccg
     3481 accttaataa ccgctacacc acctgacaat ttggccaagc gttcttgcaa tttttcacgg
     3541 tcaaattcag aagttgtagt ttcgatttga gacttgataa ccgcaacacg gtgagaaatc
     3601 gcttcaggat ttcctgcacc ttctacaata accgtgctat ctttgtccac ggtcactctc
     3661 gctgcttgac caagagcttc aattgtcgca tctttcaact caagaccaag gtcttctgtg
     3721 ataactgttc cgcctgttaa gatggcgata tcttcaagca tggctttgcg acggtcacca
     3781 aaaccaggtg ccttgactgc tactacgttg aaggttccac gaatcttgtt caaaacaaga
     3841 gttggaagag cctcgccatc cacatcatcc gcaataatca agagtggacg attgctttgg
     3901 agaatgcttt ccaaaagtgg caagatttct tggatattgg aaattttctt gtctgtaatc
     3961 aaaatgtacg gattttcaag gtcagccacc attttttcgc tatcagtcac catgtactgt
     4021 gaaaggtaac cacggtcaaa ctgcattcct tctacgactt caagctctgt ttccatacca
     4081 cgtgactctt cgatggtgat gacaccgtct ttgccaactt tttccattgc ttcagagatg
     4141 tactcaccaa ctttttcaga acgagaagat acggctgcaa cttgagcgat agcttcttta
     4201 ttggcaacag ggatggcgtt gtttttcaaa gcttcaactg ctgcggcaac tgctgtttca
     4261 atcccacgac gaataccgat tggatttgca cctgctgtga cgtttttgat tccttcacgg
     4321 acgattgctt gggtcaaaac agttgcagtt gtagttccat cacctgcgat atcattggtt
     4381 tttgaagcca cttctgatac caatttggca cccatatttt caaaatggtc ttctaattca
     4441 atttctttgg caatagtcac accgtcattg gtaatcaatg gtgagccaaa tgatttttca
     4501 agaacgacat tgcgaccttt tggtcccaag gttactttaa cagtgtctgc aaggatatcg
     4561 acaccacgga ccatagctga acgggcatct gatgaaaatt taatttcttt tgacatactt
     4621 actttctcct tctattcttc aatgattgcc aagatgttag cttcgcctac gatgatgtac
     4681 ttttcatcgc catctttgac atcaagacct gcgtgggctt caactaagac acggtctcca
     4741 gttttaacac ttggagcaac caagtcaccg ttcaaggtac gaacaccttg tccagtagcc
     4801 acaacttggg ctgttttggt tttttcttgg gctgaacctg cgagaacaaa gcccccaacg
     4861 gtttgttctt tttcttctat ttttaagacc acacggtccc ctaatggttt caacatctga
     4921 tttcctccat aatgagatag atattattag cgctctttat acctgagtgc taattcatag
     4981 ttctattgta tcacttagtc agaaataatc aagaaaaaag tctgactttc tcaagataaa
     5041 aagcctgaga ccaactcaga ctttttaatg tttatactca atgaaaatca aagagcaaac
     5101 taggaagcta gccgcaagct gctcaaagca ttgctttgat gttgtggata aagctaacgt
     5161 ggtttgaaga gattttcgaa gagtattaaa atggcaattc ttcctcttcc aagactaaat
     5221 ctgccaaatc ttggcctgca ttattttcac gcatggcacg ttgagcacga ctttccaaga
     5281 gttggaatcc tgttacaagt acttcggtca cgtagttcat ttggccattt ttctcaaagc
     5341 gacgggtacg caattctcca tcaacggaaa tgagactacc tttggttgcg tagcttgcca
     5401 aagtttctgc tagtctgccc cataggacca tattgacaaa atcagcttca cgttcaccgt
     5461 tttggtcttt gtaacgacgg ttcacagcga tagttgctcg cgctaccgac ttgtcattgt
     5521 tggttttgtg caattctggt gtagacgtta aacgcccaat catgataact ttattataca
     5581 tattttcttc ctcctactta tctattcgta ggaaatcaaa aaaagttaca gaaatttgta
     5641 acttttcgag gaaatttctt attttttatg aatcatgaaa cctgtcgcct gttgattggc
     5701 cataatggtc atatctgtaa tctgaacacg gcgaggctga ctggtcacat agactactgt
     5761 gtctgcaata tcctgagctt gcaaggcttc tattccttgg taaacggacg cagctcgctc
     5821 tttatcacca tgaaaacgaa cagttgagaa atctgtttcg acaatcccag gctgaatggt
     5881 tgtcaccttg atatccgttg cgatggtatc aattcgcagt ccatccgaaa aggtcttaac
     5941 cgcagccttg gtagctgagt aaacagcggc accagcatag gcgtagattc ctgcggttga
     6001 ccccatattg ataatatgac cttgattgac ttttatcatt gctggcaaga aacagcgagt
     6061 aaccgccatc agacctttaa cattggtatc caacatggtc aacatatcca actcctcata
     6121 gtcttgatag ggagccaagt caagagccag tccggcgttg ttgaccaaga tatcaatcct
     6181 ccctatcgtt tctagaatat cagagcaaac agtcttcacc atgaccatat ccgtcacatc
     6241 tagtggaaaa gtccagacgg tttgatttgg aaagcttact gcaaactccg acttgaggat
     6301 ttctaatctg tctatccgtc gtcctgttag aacgacatcc tcaccctgct ccagataagc
     6361 acgcgcaatc gcttcaccga ttcctgaggt tgctcccgta atcactacat tttttgccat
     6421 cttatttcct tctatcagat gctgacaagt tcctaggcag tccagtgttt cgctgggtcg
     6481 aacggtgttc cgacaacttg gtcttctgat aattcaagca ccccacgttt ttgcggagca
     6541 tttggcaaat gcaattcacg aggactacac atcatcccaa aactcttttc accacgaagt
     6601 tcgcctggga aaatgaaatt cccttttggc atcatggcac caggaagagc cacaatggtt
     6661 ttcaacccaa cacgcgcatt aggtgctcct gcaacgattt gcactatctt gtcacttgcg
     6721 actgcaactt ggcagatgtt gaggtggtca ctgtctggat gagctaccat ctcgacaatt
     6781 tcaccaacaa caaacttagg ttccttatca ttaacaattt cttctgtaaa accttccgcc
     6841 tgtaattctt ggttcaaacg agcgacttgc tcatctgata aaaagacttg accgcgctct
     6901 gcaatttcaa acaagctcga aacctcaaaa atgttccaag ccactgtttc cccattttct
     6961 ttgaggaaaa cacgggctac cttgcctttg cgttccacat tcagtttggc atctccgcta
     7021 tttttcacga tgaccataag gacatcactg acatgttctt tgttatacgt aaaaatcatt
     7081 gtttcctttt tctcctattt caatcctgct aaaaaatcgt taatttgctc cttactttta
     7141 cggtcgcgat tgacaaaacg accgatttcc ttgtcctttt ctagaacaac aaggctagga
     7201 attccgtaaa catcccagag tttggccaaa tccatatact gatctcggtc cattcgaata
     7261 aaggtgaact ctggattggt ctcttcaatc tctggtaagg caggataaat ataacgacaa
     7321 tcgccacacc agtctgccac aaaaaggaag accttcttgc ccgctttttc cactaaagat
     7381 gctaattctt ctaaacttgc tggctgtatc ataagacttc ctcctcatag actaggtctt
     7441 cattttcata gacaaaggta taatgacggc catcctcaaa aatgacgcca ccaaccaagc
     7501 tctccagact gctttcgtaa acttgaacat aaagggtcgc aatttccccc atgtcggaaa
     7561 aatggtctcg cacaatctct gtcaactctt cctgagtctt catgagctta cggtcatctg
     7621 caactttttt cgtagcaaga gcaaggcttc cgatacctag cagagccaag cctgccatcc
     7681 acattttttt agctttcata ccattcattt taacacaaaa aaggcttcag gacaaatgag
     7741 gaagcagcag aaaagcaagt aaaaagcctc ttcctttaag gaaaaagact tcttatacta
     7801 agagcaaact aggaagctag ccgcaggctg ctcaaaacac ggttttgagg ttgtagataa
     7861 ggcgacgttg acgtggtttg aagagatttt caaagagtat tattcttatt gccaggcacc
     7921 taagttgcca acgtagtaac tatcaggtgt gtaggtattg cgaagcatct tacctgatga
     7981 agccagataa tactacttgc cattgtcttt gacccaatca ttcgcaatca tggaaccaga
     8041 agaacttaca taataccatt ctcccttgtc ataaacccaa gtactgactt tcatggttcc
     8101 tgagcaatta aaggcaaaaa aactgtccaa tatcattcgt tttttaaaag catttgacac
     8161 tacatcatct acgctgtagt acatagatac atcaaacgta aaagccaaaa tatcgaaaaa
     8221 tatacaactt ttaaaggcag catttcattt tttaaagtct aacaaccata gaactgaaat
     8281 cagagcaagg catcaatttc ctactcttag tacgtctatt ttgatggttg aagtgaagat
     8341 ttttttattt aacgtagaca atttccaact tcccaaaagc cacatctcca cggatagtca
     8401 aggttttgct ggttggggct acaggagcgt cagccttagc tgcaccaaag gaggtttcta
     8461 ctttcaaatc tacacgccag tgttgtggaa catagacggt tgcattcccg aaggccactt
     8521 caatatttaa agttgcaaaa tcacctagca tctctgcatt atcatagtag attttagcat
     8581 ccccaaaagc gacttccact tggtcatcta cgagatcttg atcttgctta tagaaggtcc
     8641 cgctaccaaa agcgacttcc ttatccgtga cgactgtttt tttcccattg taccaccatt
     8701 ttttttcatt ccagaactta cttgaatgcg tcagataacc aacaccaagt accaccaaga
     8761 tgctagccca aataagagaa tgattggtaa ctggtaacaa gtcataagcg taatttgcaa
     8821 tgatgagcgc cagtaaacct gtaaaaactg ccgaagtgag atgacgtcta aggatggact
     8881 caatggactt ataagcaaaa aaaacaatac ctagtaaagg ccatatttta ccatccaaag
     8941 aaggaattcc aaaattccct tgcagcaaga tccaagctgc taaaaccaac aaaacaatac
     9001 caaatgcttt ctttttcatg ttttttacct catgtttctt agattttctt ttaggaggga
     9061 ttggtaatgc cgtgagacat gaacctcctt gtgcgtctga taaaaggaaa tggtgcccgt
     9121 tcctgaaaag gacttgtcca ctgagtaaat ctgacggatg tttgcgatcg ttgacttgga
     9181 aactcgatta aaatagcgag gcaagataga ctccaactca tagagcttga ggcgaacctc
     9241 ataagcttcc ttctggttat gagcgtagat cttgctccct tctgtttcaa agaagagaat
     9301 ttctgacagg tctagataat attcacctgt ccccttgtaa aaagtcaacc tcggagcctt
     9361 tgactcttgc aagagccgtt gcaagtctgc aatttcatct gtcaaagtgg gggtcttgat
     9421 gacaatttca gtctcctcta aattgccgtc aatctcaatt cgtaacttca tcacatctcc
     9481 tttctgactc tactatatca aagctaagtt aggaatacaa gggcaaaaaa gcaagtggtc
     9541 aatttgaagc agtaagtggt tgtaggacta gcttaactta catgtaagaa taggaagaaa
     9601 aggaatcccc acaccaaacc acaagcatag ccaaccaaga catccttggg ataatgaaca
     9661 ccccctaaaa ccctcaccaa ccccagcaaa gctgaaaaga tcaagcatac taagccaata
     9721 ggtagactag catgcagaca ggccatggag atgatagttg ccgaaaagac atggcgactg
     9781 ggcatcgacc gtcccgaact atccttatca agaaggggac agatatccca agtttcataa
     9841 ggtctcgggt gattgatttt cttacgaaac agggacaagg ccacaaaacc tgatgcagga
     9901 ataagcacac aaaccccaac ttgctgacca agtcctagtt gcaggtaagt ggtgactagc
     9961 aagatcagat agaccagggg catggcgact gtcatcaaac gattgaaact gcgtaatagg
    10021 aataaaagaa ttggacgact agttagtctg gagctgatat ttcgatacca ttcttgataa
    10081 tttttcattt atgcttctca tacttttcta gaacttgttg agatgttttc cccttggcaa
    10141 gccaatccac tagcttgtcc aagcgacgta tttcctgcat cagaggatca tcaatttcct
    10201 caatacggac actgcaaatc ttccctgtaa ttgcaattcg ttcagggaca taatatggtg
    10261 cttgtctaaa aaaatctccg taagtaacat ccctatccag acaagcaaga acatcactca
    10321 cttcataccc tgtcaaccaa ctggtcactt ggtgaactga ctctgccttt ccaccctttc
    10381 gctcaacttt tgcaatcaag gctaagtaga cagcagcaaa tttcatattg tataatttct
    10441 gactcatact tctctctttc tatgtgtact agtataaata agaaaaagaa ggccgtcaag
    10501 ccttcttttg atttattctt ctgcttcatc ttctgtaaat tgactattgt acaagtcagc
    10561 gtagaagcca ccttgcgcca tcagttcctc atagttgcct tgctcgatga tatttccatc
    10621 tttcatgacc aagatcaagt ctgcatttcg gatggttgac aagcggtggg caatgacaaa
    10681 ggatgtgcgt ccttccatca aacggtccat ggctttttgg atcaattcct ctgtccgtgt
    10741 gtcaacagaa gaagtcgcct catccaaaat caaaagcggt gcatccttaa gaagggcacg
    10801 agcaatagtc aatagttgtt tttgtcctac agacaaggtc acggtgtcat ccaagatggt
    10861 atcatagcca tctggcaagg tcataataaa gtggtgaatt cccacagcct tactagcttc
    10921 catcattcgt tcatcactaa tccctatttg attatagatg agattgtctc gaatagttcc
    10981 ttcaaagagc caggtatcct gcaagaccat tgaaaaggca tcatgcactt ctgaacgcgt
    11041 catagccttg gtatccacac catcaatgtg aatacttccc ttatcaatct catagaattt
    11101 catcaaaaga ttgacaatgg ttgtcttacc agtcccagtc ggcccaacaa tggcaacctt
    11161 ttgaccagca tgaactgtcg cagagaagtc atagtcttga acattgacac cgtccaccag
    11221 aatttctcct gctgacacgt cgtagaaacg tggaatcaga ttgaccagag ttgatttacc
    11281 agaacctgtt gacccaataa aggccactgt ttgaccagtt tctgctttaa agctaacatg
    11341 ttcaataact gcctccgaat ttgccgcata gcggaaggtc acatccttaa actcgacctg
    11401 acctttgaag ttttcatcag tcagctgcac ttgaacaggg ttttggatag aagaatgcaa
    11461 atctaaaact tgattaatcc gcttagcaga gaccatagtt tggggaagaa cgatgaagag
    11521 tgctcccatg agaaggaagt ccatgacaac ctacatggca taagacatga aaacaatcat
    11581 gtcactaaag agaggcagac gcgctatcgg agcagcgtcg ttaatcacat aggccccaat
    11641 ccagtaaatc gccacactca aaccacttga aatccccatc atgataggat tcaaaatagc
    11701 cataagacgg ttgacaaaca aatttaaacg ggtcaattca tcatttactg ctgcaaattt
    11761 ttcattttga taatcctctg cattgtaggc acgaacgaca cgaatacctg ttaaactctc
    11821 acgagtgata ctgttcagtt tatctgtcag cccctgaatc aaggactgtt ttggaaaggc
    11881 tagcgtcatc aaaacggtcg tcatcaggac gttgacaatc actgccacaa gtacggccca
    11941 gagccagtat tctgaatgac ctaaaatctt cccaatagcc cagatagcca taattggacc
    12001 acacgttacc acttgcaagt ccatagtaat caacatttga acttgagtaa tgtcattggt
    12061 agtacgcatc aagaggctag gaattgaaaa tttcttaatc tctgtctgcg agtaatccaa
    12121 aactcggtta aaaatatcac ttctcagcct actagtataa gaagccgcca ctcgggatgc
    12181 aaaaaatcca actgcaacta cggacaagaa ggcaagaaag ggcattccca tcatcatgct
    12241 tgccggctgc cacaactcat ctaaattagt tccttgacta cctagcaaat ccgtaatttt
    12301 cgagatatag gtcggcactt ccaactctag atagaccgaa aagcaagtaa agagaatggc
    12361 tagtaaaatc atcccccatt cttttctact aattcttttg actaatttct ttattctctc
    12421 ctcctattcc cttgatattt gcctgtagtt gaccgagaac tttctcaaaa atcagtaatt
    12481 catcttcatc aatgtcttcc atcaactgct tgtctatgcg ttcaaaaaaa gccttaacct
    12541 gttgcatctg agaacgtgct ttgtccgtca gacgaacaaa cttagcccgc ttatcaacag
    12601 gactcgcctc caattccacc aaaccatttt gcactatacg cttaaccaga ttactagcaa
    12661 cagacttggt aatattgagt tcctgctcga tatctttaat caagaccaag tcttggtttt
    12721 tctcgcgatt atccaaaaaa tgcacaacct gaccttgcgg cccacccata aattcaatgc
    12781 cgcaacgttt ggcttccttt tgcaccatca ggtgaatttg atgaccaaaa cgcttaaaga
    12841 ctaacatcgg tttatccata atctccccct tctaaataaa aatagttctc tggagaataa
    12901 ttaaatttct atgagaacta ttttcttgat taaaaaaatc ccaagtgatt ttctcactta
    12961 ggatcatgtt ctataggtta aattaaaacc catctacgtt cgtataaatc ttttggacgt
    13021 cttcgtcgtc ttcaagaacg ctgtaaagtt tttcaaaggt ttcaaggtct tcgcctgaca
    13081 attccacttc tgactgagga atcatttcca attcagtcac ttggaattct tcaataccag
    13141 actcacggag ggcaacgata gccttgtgaa ggtcagttgg cgctgtgtaa actgtgattg
    13201 taccttcttg tgcttctacg tcatccacat ccacatccgc ttcgagcaat tgctcaaaga
    13261 ctgcgtccgc atcttcacct ccaaatacaa taacaccttt gttgtcaaag aggtaagaaa
    13321 cagaacctga agcgcccatg tttccgccgt ttttaccaaa ggctgcacgg acattggctg
    13381 ctgtacggtt gacgttagaa gtcaaagtat ccacaattag catagagcca tttggcccaa
    13441 aaccttcgta acgtccttct gtaaaggttt cgtctgtgtt tcctttggct ttatcaatcg
    13501 ctttatcgat aatgtgtttt ggcacttggg cttgtttagc acggtcgata acgaatttca
    13561 aagctgagtt tgattctgga tctggatcac cttttttagc tgctacatag atttctacac
    13621 caaattttgc atatacttta gagttggctc catctttagc cgttttcttg gctacgatat
    13681 tggcccattt acgtcccatt aggaatctcc ttttttcaca ttttaatctt tcttattata
    13741 acacaagttt ttttgatttt cactagagga aatggatttt attagcaaat caagctagga
    13801 tagcacttta cctgctaaga tggtcttgcc tttctatctt tatcaacaga cactcatcca
    13861 cattcaaaaa acaaactaga ccattatctg caaatagaaa gtttcagcca agtttgacaa
    13921 agtcagctca aattactgtt tgaagtttgt agatataagc gacaaaaaca atcatactgc
    13981 accttttgtt gacagtctac tccagacata tcatagttca agtaaatact ttgaaatcca
    14041 acagttctta taggcgctat tgtattctaa gaaatcaata gaagagtttc taagcaaacc
    14101 tctaatactc aataaaaatc aaagagcaaa ctagaaagct agccgcaggt tgctcaaaac
    14161 actgttttga ggttgcggat agggctgaca tggtttgaag agattttcga agagtataat
    14221 ttacgtgttc ctaagatgga gaagttagac tagtacactg gcacttctaa accattgcta
    14281 gcaattgatt tgttcatatt taatttcatt ttttccataa atgggtatta gatataaaca
    14341 gcaaaatatt tccgatacgt gtcattcttg aatttccaat catctaaaac aagtaaagga
    14401 taatcaatcc cctgtatatc aaggaattgg ctaccctttt tactttttta cacatcctgt
    14461 ttgatagact cattttaaca tcacgagcat actccaatgg aaatcgctag gcaagagata
    14521 aactttcaga tattcgcaga gagctcatcg cctctttttg tcgcaaacat tcttctctcc
    14581 taatcatttt ctaccttatc ctctacctga ggatagagag ttgttcccca aatagaaatc
    14641 gtccgcttac gcactagtgg caaatcggtt ttttcataaa ccgtacgcca ccattcccag
    14701 gcaagcccgg tacactctct aattttgaca gagagattgc gaacattccc ttttaaagga
    14761 atactagtgg taaagtgagc cgtcaaatcc tgcccatttc tgtcccaagc cttaggagtc
    14821 aagacttcct tgccttgatg atcataggat aattcatccc aagtaatata atattgggca
    14881 acataggcac cactatgatc cagcagtaaa tctccgtttc tgtaagctgt aaccttagtc
    14941 tcaacatagt ctgtactgtt ttgaaaggtc gcaactacat tgtcacgtaa aaaagaagtt
    15001 gtataggaaa tcggcaagcc tggatgatcg gctgtaaagc gactgccttc ttgaatcaag
    15061 tcctctacca tatccacctt gcctgttaca actcgggcac ccgaacttgg gtcgccccct
    15121 aaaataaccg ccttcacttc tgtattgtcc aaaatctgct tccactctgt ctgaggagct
    15181 actcctttta tcaaagattc aaaagcagcc tctacttcat cactcttact cgtggtttcc
    15241 aacttgagat agacttggcg cccataagca acactcgaaa tatagaccaa aggacgctct
    15301 gcagaaattc ctctctgcct taaatcctct accgttacag tatcttgaaa cacatctcct
    15361 ggatttttaa cagcatctac gctgactgta taataaatct gcttaaaatt aacaatctga
    15421 atctgctttt cgcctgaatg gacagagtta aaatcaatat caagagaatt ccctatcttt
    15481 tcaaagtcag aaccaaactt gaccttgagt tgttccatgc tgtgagccgt gattttttca
    15541 tgctgcattc tagctgggac attattgacc tgaccataat cttgatgcca cttagccaac
    15601 aaatcgttta ccgctccgcg aacacttgaa ttgctggggt cttccacttg gagaaagcta
    15661 tcgctacttg ccaaaccagg caaatcaata ctataagtca tcggagcacg atcgaccgca
    15721 agaagagtgg gattattctc taacaaggtc tcatccacta cgagaagtgc tccaggatag
    15781 aggcgactgt cgttggtagc tgttacagaa atatcacttg tatttgtcga caagctccgc
    15841 ttctttcttt cgataacaac aaactcatcg ggtagctgat taccctcttt gatgaaacga
    15901 ttttcaatac tttctccctg atgggtcaag agtttctttt tatcgtaatt catagctagt
    15961 ataaagtcat ttactgcttt atttgccatc ttctacctcc taataagttc ctggattgag
    16021 ttgcataaac tcagacttgt tcagcgaaat cagccgtggt tggactaagt aatccaaaat
    16081 ttcctcgtac aattcttctg agacattgcg tcgccgtctg gctaaataag aagtcggaat
    16141 gaccgtatta tccaacataa ataccttatc taagtcaatc aaggttggtc ttgtaaaagg
    16201 attacgagct agatccggct cttctatcat aaagttcttg accaaacgtc tggtcaagag
    16261 agctggtttg aaggtctgat ttttaaccaa ctctttgttt ttagtcatgc tgttgtcaat
    16321 acagatatac atatgattct tcacagccaa atcgctacta atagtcggaa aaggcaaata
    16381 aagagctaca acatctcctc tcttaatcaa gcaagagcac ccccttttct cctaatgtaa
    16441 catagacagg attgaccaag tcttctgatt gactcagaat ttccaaagtt tgagtttggc
    16501 gcgctgtcaa tttagtagca tcttgtctct tcaatacaaa atgcttgtcg ccaataacct
    16561 tgacaatata atccttctcc aaagctgact ggtaaatcca catcagatgt tgtctgtcct
    16621 gagaactcaa gagagaagga ttttcaagcc tcccgatagt ctgataaaaa tcaaaaacag
    16681 gagctaactc ctgccaatct gattggctag ttgtcaaggc tagaaaaagg gctttgcgag
    16741 ctgatacttc ttggttagcc ttgagagtta ctttcccctc caagtttttt agaaatcggg
    16801 aaactccaga aagcaaattt ttctctaact gcgagaaata aaaacctttc gttcccagac
    16861 ataagtcttt catgtcgctt tctctagcaa ataagagctc aaacatttga tagtaaaaga
    16921 aaaatatctg gcactgggtc gcgctcatct tttccttatc ggcttctttt tttaaccaga
    16981 gcaagggcga caggtagctg gattgagaca tttcctctac ctcctactct tttttaactg
    17041 gagcatctgc actagctgcc acttcttttg actggatact ttcccactgg ttaatctcct
    17101 ctgagataag accttcgcat gtcttgacaa atagggcaaa agccttggtc tttcctgcat
    17161 atttctccgt ttggcattga tagaggaatt tttctttctc caggagttgc gcagtttttt
    17221 ggtaagaaat ccaattttcc tttgcattat acaaattgat aatcccctca cacagcaagc
    17281 cgagactgga taaggcaacc gaaatcaaac ggtagcgatc acctggcata ggaatagcac
    17341 aaaagacagc tatgaggaaa cctgccacga tttctgttat ttttaatacc ttatagcgcc
    17401 tacgatgttg aacgcttttc tttaaaaaat gagctatctg tacgtctaat cgctctgtca
    17461 ggtacatttc ttctggcgtc atattcgtaa ctcctttcat ttactttgat aaccatagta
    17521 taacatattt gaatatcaaa gtatagtaaa aactggacta taacttatta gactccctgc
    17581 gaaacaaaat atggtatagt agttctatga attatgaagc aagtaaacaa ttaactgata
    17641 cacgatttaa gcgtcttgtt ggtgttcagc gtaccacttt tgaagagatg ttagctgtat
    17701 taaaaacagc ttatcaaaaa a
//
LOCUS       DAVBBO010000047        17282 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ST1
            SAMEA2066453-rid20184263.denovo.047, whole genome shotgun sequence.
ACCESSION   DAVBBO010000047 DAVBBO010000000
VERSION     DAVBBO010000047.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2066453
            Sequence Read Archive: ERR351777
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 17282)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 17282)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980402.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980402.1
            Genome Coverage       :: 176x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:17:33
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,141
            CDSs (total)                      :: 2,104
            Genes (coding)                    :: 1,953
            CDSs (with protein)               :: 1,953
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 16S)
            partial rRNAs                     :: 1 (23S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 151
            CDSs (without protein)            :: 151
            Pseudo Genes (ambiguous residues) :: 0 of 151
            Pseudo Genes (frameshifted)       :: 73 of 151
            Pseudo Genes (incomplete)         :: 76 of 151
            Pseudo Genes (internal stop)      :: 40 of 151
            Pseudo Genes (multiple problems)  :: 32 of 151
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..17282
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2066453-rid20184263.denovo.047"
                     /strain="ST1"
                     /db_xref="taxon:1313"
     gene            complement(<1..692)
                     /locus_tag="VQU30_001600"
     CDS             complement(<1..692)
                     /locus_tag="VQU30_001600"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001021424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MucBP domain-containing protein"
                     /protein_id="HET2447675.1"
                     /translation="MNIILIAKPLRENTNTKANALNNGWARSGSEEFKKFSHFVGVDK
                     GIVRTNVLTGKKLSDKIRKEVGSGDSKLGKGGYFSTGDVLLGKDVVSYTVQVFSENNE
                     RVGVNTQSYRVQYNLPILADFSVIQDTVEPSRTVVEKIIPKLNIPEEEKGKITEEIKK
                     KKKTSELAELISENVKVRYVDEQGRLLSLKNDTGIGEKESDGTYITNKKQLIGTSYNV
                     TDKKLSSMTTTDG"
     gene            complement(803..1057)
                     /locus_tag="VQU30_001601"
     CDS             complement(803..1057)
                     /locus_tag="VQU30_001601"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001842111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2447676.1"
                     /translation="MLNVDQDFMSISKSNKSGSDWKKTFTVRITNRLANDLNNVLKQV
                     DKDTPNTPTWLNSAASKAKDDDRVYKLLKTLIPGENYLSC"
     gene            complement(1415..1948)
                     /locus_tag="VQU30_001602"
     CDS             complement(1415..1948)
                     /locus_tag="VQU30_001602"
                     /inference="COORDINATES: protein motif:HMM:NF024751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HET2447677.1"
                     /translation="MTIFKEQESEKVAEFLDILDNLKDLPIVYIDETGINRYLYRPYA
                     GAPRGEKVYEKISGRRFERTSIVAGQVDGEFIAPMIYKKSMTSDFFVEWFKTQLLPAL
                     KTPHVIVMGNASFHPKNILDELCIQDKHFFLPLPPYSPDLNPIEQAWAILKKKVTDLL
                     REVPTIFECLECFFKTR"
     gene            complement(1935..2261)
                     /locus_tag="VQU30_001603"
     CDS             complement(1935..2261)
                     /locus_tag="VQU30_001603"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HET2447678.1"
                     /translation="MAYNTDFKQGALDSIKGGHRHVEAAKVFWCWRQNSLHVGKERRE
                     QRNLERKKRVVKKRKIPLEELKAFVEAHPDAFLREIAAHFDCAVPSVWAALKQIKVTL
                     KKDDDL"
     gene            2495..4213
                     /locus_tag="VQU30_001604"
     CDS             2495..4213
                     /locus_tag="VQU30_001604"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004252698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phospho-sugar mutase"
                     /protein_id="HET2447679.1"
                     /translation="MSYQENYQKWVDFVELPDYLRQDLENMDEKTKEDAFYTNLEFGT
                     AGMRGLVGAGTNRINIYVVRQATEGLARLIESKGGNEKERGVAIAYDSRHFSPEFAFE
                     SAAVLAKHGIKSYVFESLRPTPELSFAVRHLNCFAGIMVTASHNPAPFNGYKVYGEDG
                     GQMPPHDADALTTYIRAIENPFAVEVADVETEKASGLIEVIGEAVDVEYLKEVKDVNI
                     NPALIEEFGKDMKIVYTPLHGTGEMLARRALAQAGFDSVQVVEAQATADPDFSTVTSP
                     NPESQAAFALAEELGRQVGADVLVATDPDADRVGVEVLQKDGSYLNLSGNQIGAIMAK
                     YILEAHKNAGTLPENAALCKSIVSTDLVTKIAESYGATMFNVLTGFKFIAEKIQEFEE
                     KHNHTYMMGFEESFGYLIKPFVRDKDAIQAVLVVAELAAYYRSRGLTLADGIEEIYKE
                     YGYYAEKTISVTLSGVDGAEQIKAIMAKFRNNAPKEWNATAITVVEDFKAQTATVADG
                     TVTNLTTPPSDVLKYTLADGSWIAVRPSGTEPKIKFYIAVVGETNEESQAKIANIEAE
                     INAFVK"
     gene            4324..4671
                     /locus_tag="VQU30_001605"
     CDS             4324..4671
                     /locus_tag="VQU30_001605"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000434646.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin"
                     /protein_id="HET2447680.1"
                     /translation="MEQFLDNIKDLEVTTVVRAQEALDKKETATFFIGRKTCPYCRKF
                     AGTLSGVVAETKAHIYFINSEEPSQLNDLQAFRSRYGIPTVPGFVHITDGQINVRCDS
                     SMSAQEIKDFAGL"
     gene            complement(4949..5785)
                     /locus_tag="VQU30_001606"
     CDS             complement(4949..5785)
                     /locus_tag="VQU30_001606"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000759190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter substrate-binding
                     protein"
                     /protein_id="HET2447681.1"
                     /translation="MKKWMLVLVSLMTALFLVACGKNSSETSGDNWSKYQSNKSITIG
                     FDSTFVPMGFAQKDGSYAGFDIDLATAVFEKYGITVNWQPIDWDLKEAELTKGTIDLI
                     WNGYSATDERREKVAFSNSYMKNEQVLVTKKSSGITTAKDMTGKTLGAQAGSSGYADF
                     EANPEILKNIVANKEANQYQTFNEALIDLKNDRIDGLLIDRVYANYYLEAEGVLNDYN
                     VFTVGLETEAFAVGARKEDTTLVKKINEAFSSLYKDGKFQEISQKWFGEDVATKEVKE
                     GQ"
     gene            complement(5798..6427)
                     /locus_tag="VQU30_001607"
     CDS             complement(5798..6427)
                     /locus_tag="VQU30_001607"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000891751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HET2447682.1"
                     /translation="MLELRNINKVFGDKQILSNFSLSIPEKQILAIVGPSGGGKTTLL
                     RMLAGLETIDSGQIFYNGQPLELDELQKRNLLGFVFQDFQLFPHLSVLDNLTLSPVKT
                     MGMKQEEAEKKASGLLEQLGLGGHAEAYPFSLSGGQKQRVALARAMMIDPEIIGYDEP
                     TSALDPELRLEVEKLILQNRELGMTQIVVTHDLQFAENIADVLLKVEPK"
     gene            complement(6437..7078)
                     /locus_tag="VQU30_001608"
     CDS             complement(6437..7078)
                     /locus_tag="VQU30_001608"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004253193.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HET2447683.1"
                     /translation="MSYLFEILPSLLNGASTTVQVFALVLLFSIPLGVLIAFALQVHW
                     KPLHYLINIYIWVMRGTPLLLQLIFIYYVLPSIGIRLDRLPAAIIAFVLNYAAYFAEI
                     FRGGIDTIPRGQYEAAKVLKFSPFDRVRYIILPQVTKIVLPSVFNEVMSLVKDTSLVY
                     ALGISDLILASRTAANRDASLVPMFLAGAIYLILIGIVTIISKKVEKKYSYYR"
     gene            complement(7224..8453)
                     /locus_tag="VQU30_001609"
     CDS             complement(7224..8453)
                     /locus_tag="VQU30_001609"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864303.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetratricopeptide repeat protein"
                     /protein_id="HET2447684.1"
                     /translation="MNNSQQMLQALEEQDLTKAEHYFAKALENDSSDLLYELATYLEG
                     IGFYPQAKEIYLKIVEDFPEVHLNLAAIASEDGQIEEAFTYLEEIQADSDWYVSSLAL
                     KADLYQLEGLTDVAREKLLEALTYSEDSLLILGLAELDSELENYQAAIQAYAQLDNRS
                     IYEQTGISTYQRIGFAYAQLGKFETATEFLEKALELEYDDLTAFELASLYFDQEEYQK
                     ATLYFKQLDTISPDFEGYEYGYSQALHKEHQVQEALRIAKQGLEKNPFETRLLLAASQ
                     FSYELHDASGAENYLLTAKEDAEDTEEILLRLATIYLEQERYEDILDLQSEESENLLT
                     KWMIARSYQEMDDLDTAYEHYQELIGDLKDNPEFLEHYIYLLRELGHFEEAKVHAHTY
                     LKLVPDDVQMQELFERL"
     gene            complement(8443..9609)
                     /locus_tag="VQU30_001610"
     CDS             complement(8443..9609)
                     /locus_tag="VQU30_001610"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000435446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HET2447685.1"
                     /translation="MEQKEKHFSLSWFFKWFLDNKAITVFLVTLLLGLNLFILSKISF
                     LFSPVLDFLAVVMLPVILSGLLYYLLNPIVDWMEKHKVNRVIAITIVFVIIALFIIWG
                     LAVAIPNLQRQVLTFARNVPVYLEDIDRIVNGLVAQHLPDDFRPQLEQVLTNFSSQAT
                     VLASKVSSQAVNWVSAFISGASQVIVALIIVPFMLFYLLRDGKGLRNYLTQFIPRKLK
                     EPVGQVLSDVNQQLSNYVRGQVTVAIIVAVMFIIFFKIIGLRYAVTLGVTAGILNLVP
                     YLGSFLAMLPALVLGLIAGPVMLLKVVIVFIVEQTIEGRFVSPLILGSQLNIHPINVL
                     FVLLTSGSMFGIWGVLLGIPVYASAKVVISAIFEWYKVVSGLYELEGEEVKSEQ"
     gene            9753..10766
                     /locus_tag="VQU30_001611"
     CDS             9753..10766
                     /locus_tag="VQU30_001611"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000665618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactonase family protein"
                     /protein_id="HET2447686.1"
                     /translation="MKETVYFGTYTRRTSQGIYKADFDTETGQLSNLELFAAEPSPTY
                     LAFDQHQHLYTVGSQDDKGGIAAYQTDGTVLNHVVEEGAPHCYVAVDEKRDLVYAANY
                     HKGQVLVYKRQEDGSLLLSDMDQHSGQGPHENQASPHVHYTDLTPDHYLVTCDLGTDQ
                     VITYDLDQEGKLSKLYTYHSKPGAGSRHIIFHNHYKIAYLICELNSTIEVLIYDGVGE
                     FERMQVISTLPEAYEGFNGTAAIHLSKDGKYLYASNRGHDSIAVYTILADGSLELLEI
                     VPTHGQTPRDFDLTPDQKFLIVVHQDSDNATVFKRNCDNGRLAELSNDFHVPEAVCIR
                     FAP"
     gene            complement(10811..11230)
                     /locus_tag="VQU30_001612"
     CDS             complement(10811..11230)
                     /locus_tag="VQU30_001612"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397408.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit epsilon"
                     /protein_id="HET2447687.1"
                     /translation="MAQLTVQIVTPDGLVYDHHASYVSVRTLDGEMGILPRHENMIAV
                     LAVDEVKVKRIDDKDQVNWIAVNGGVIEIANDMITIVADSAERARDIDISRAERAKLR
                     AERAIEEAQDKHLIDQERRAKIALQRAINRINVGNRL"
     gene            complement(11241..12647)
                     /gene="atpD"
                     /locus_tag="VQU30_001613"
     CDS             complement(11241..12647)
                     /gene="atpD"
                     /locus_tag="VQU30_001613"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit beta"
                     /protein_id="HET2447688.1"
                     /translation="MSSGKIAQVIGPVVDVLFAAGEKLPEINNALVVYKNDERKTKIV
                     LEVALELGDGMVRTIAMESTDGLTRGMEVLDTGRPISVPVGKETLGRVFNVLGDTIDL
                     EAPFTEDAERQPIHKKAPTFDELSTSSEILETGIKVIDLLAPYLKGGKVGLFGGAGVG
                     KTVLIQELIHNIAQEHGGISVFAGVGERTREGNDLYWEMKESGVIEKTAMVFGQMNEP
                     PGARMRVALTGLTIAEYFRDVEGQDVLLFIDNIFRFTQAGSEVSALLGRMPSAVGYQP
                     TLATEMGQLQERITSTKKGSVTSIQAIYVPADDYTDPAPATAFAHLDSTTNLERKLVQ
                     LGIYPAVDPLASSSRALAPEIVGEEHYAVAAEVKRVLQRYHELQDIIAILGMDELSDE
                     EKTLVARARRIQFFLSQNFNVAEQFTGQPGSYVPVAETVRGFKEILDGKYDHLPEDAF
                     RGVGSIEDVIAKAEKMGF"
     gene            complement(12733..13611)
                     /locus_tag="VQU30_001614"
     CDS             complement(12733..13611)
                     /locus_tag="VQU30_001614"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002895995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit gamma"
                     /protein_id="HET2447689.1"
                     /translation="MAVSLNDIKTKIASTKNTSQITNAMQMVSAAKLGRSEEAARNFQ
                     VYAQKVRKLLTDILHGNGAGASTNPMLISRSVKKTGYIVITSDRGLVGGYNSSILKAV
                     MELKEEYHPDGKGFEMICIGGMGADFFKARGIQPLYELRGLADQPSFDQVRKIISKTV
                     EMYQNELFDELYVCYNHHVNTLTSQMRVEQMLPIVDLDPNEADEEYSLTFELETSREE
                     ILEQLLPQFAESMIYGAIIDAKTAENAAGMTAMQTATDNAKKVINDLTIQYNRARQAA
                     ITQEITEIVAGASALE"
     gene            complement(13627..15132)
                     /locus_tag="VQU30_001615"
     CDS             complement(13627..15132)
                     /locus_tag="VQU30_001615"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011889023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit alpha"
                     /protein_id="HET2447690.1"
                     /translation="MAINAQEISALIKQQIENFKPNFDVTETGVVTYIGDGIARAHGL
                     ENVMSGELLNFENGSYGMAQNLESTDVGIIILGDFTDIREGDTIRRTGKIMEVPVGES
                     LIGRVVDPLGRPVDGLGEIHTDKTRPVEAPAPGVMQRKSVSEPLQTGLKAIDALVPIG
                     RGQRELIIGDRQTGKTTIAIDTILNQKDQDMICIYVAIGQKESTVRTQVETLRQYGAL
                     DYTIVVTASASQPSPLLFLAPYTGVAMAEEFMYQGKHVLIVYDDLSKQAVAYRELSLL
                     LRRPPGREAFPGDVFYLHSRLLERSAKVSDELGGGSITALPFIETQAGDISAYIATNV
                     ISITDGQIFLGDGLFNAGIRPAIDAGSSVSRVGGSAQIKAMKKVAGTLRIDLASYREL
                     EAFTKFGSDLDAATQAKLNRGRRTVEVLKQPVHKPLPVEKQVTILYALIHGFLDTVPV
                     DDIVRFEEEFHAFFDAQHPEILETIRDTKDLPEEAVLDAAITEFLNQSSFQ"
     gene            complement(15147..15683)
                     /locus_tag="VQU30_001616"
     CDS             complement(15147..15683)
                     /locus_tag="VQU30_001616"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000358986.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit delta"
                     /protein_id="HET2447691.1"
                     /translation="MDKKTVKVIEKYSMPFVQLVLEKGEEDRIFSDLTQIKQVVEKTG
                     LPSFLKQVAVDESDKEKTIAFFQDSVSPLLQNFIQVLAYNHRANLFYDVLVDCLNRLE
                     KETNRFEVTITSAHPLTDEQKTRLLPLIEKKMSLKVRSVKEQIDESLIGGFVIFANHK
                     TIDVSIKQQLKVVKENLK"
     gene            complement(15683..16177)
                     /gene="atpF"
                     /locus_tag="VQU30_001617"
     CDS             complement(15683..16177)
                     /gene="atpF"
                     /locus_tag="VQU30_001617"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006145707.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit B"
                     /protein_id="HET2447692.1"
                     /translation="MHVTVGELIGNFILITGSFILLLVLIKKFAWSNITGIFEERAEK
                     IASDIDRAEEARQKAEVLAQKREDELAGSRKEAKTIIENAKETAEQSKANILADAKLE
                     AGHLKEKANQEIAQNKVEALQSVKGEVADLTISLAGKIISQNLDSHAHKALIDQYIDQ
                     LGEA"
     gene            complement(16191..16907)
                     /gene="atpB"
                     /locus_tag="VQU30_001618"
     CDS             complement(16191..16907)
                     /gene="atpB"
                     /locus_tag="VQU30_001618"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000392848.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit A"
                     /protein_id="HET2447693.1"
                     /translation="MEESINPIISIGPVIFNLTMLAMTLLIVGVIFVFIYWASRNMTL
                     KPKGKQNVLEYVYDFVIGFTEPNIGSRYMKDYSLFFLCLFLFMVIANNLGLMTKLQTI
                     DGTNWWSSPTANLQYDLTLSFLVILLTHIESVRRRGFKKSIKSFMSPVFVIPMNILEE
                     FTNFLSLALRIFGNIFAGEVMTSLLLLLSHQAIYWYPVAFGANLAWTAFSVFISCIQA
                     YVFTLLTSVYLGNKINIEEE"
     gene            complement(16942..17142)
                     /locus_tag="VQU30_001619"
     CDS             complement(16942..17142)
                     /locus_tag="VQU30_001619"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015545704.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit C"
                     /protein_id="HET2447694.1"
                     /translation="MNLTFLGLCIACMGVSVGEGLLMNGLFKSVARQPDMLSEFRSLM
                     FLGFAFIEGTFFVTLVFSFIIK"
BASE COUNT         5223 a         3784 c         3096 g         5179 t
ORIGIN      
        1 ccgtcagtag tagtcatgct actgagtttt ttatctgtga cattgtagct ggtaccaatc
       61 agttgttttt tattggtaat gtaggttccg tcactttctt tttctccaat tccagtatca
      121 tttttcaatg atagcaaacg cccttgttca tcaacatagc gaactttcac attttctgag
      181 attagttctg ccaattctga ggtttttttc tttttcttga tttcttcggt tattttccct
      241 ttctcttctt cgggaatatt tagttttgga atgatttttt caacaacggt tcgtgatggt
      301 tccacagtat cttggatgac tgaaaagtca gctagaattg ggagattata ctgaacacgg
      361 taactttgag tgtttactcc tactctttca ttattctctg aaaatacttg tacggtataa
      421 gaaacaacat cttttcctaa tagaacatcc ccagtagaga aatagccgcc ttttcctagt
      481 ttgctatctc cagagcccac ttctttccta attttatcag atagtttttt accagtcagt
      541 acattcgttc gcacaatccc tttgtctacc cctacaaagt gggagaactt tttgaactct
      601 tcagaaccag atctagccca accattatta agggcatttg cttttgtatt tgtattctct
      661 ctcaaaggtt tggcgattag aattatattc atcggcactt agagttgctg ctatatctga
      721 ctcttgaata ccaacttcct tactaccatt tctagcggca gtatatgtgt atttatctgt
      781 ttctacttct agctgattat ccttaacatg ataggtaatt ttctcctggt ataagagtct
      841 tcagtagttt atatactctg tcatcatctt tagctttaga agcagctgag tttagccaag
      901 ttggggtatt aggagtatct ttatcaacct gtttcaagac attattcaag tcatttgcta
      961 gcctattggt tatcctcact gtgaaagttt tcttccagtc tgaaccactt ttattagact
     1021 tagatatgct catgaaatcc tggtcaacat tcaacacaat atcgccttgt tttttagcat
     1081 cttccgttgc ttctgcttca aattgatcat ggagtttttg ttgctctggt gtatagtttt
     1141 tttatttaca cgatttaatg tactattttt tattttagta ttaagaactc cattaatacg
     1201 atttttaaac tctgcttcaa aaaatccctt aatttgttgg tgcgcaagtt caacattcaa
     1261 acctttctta tacaagtctt cattctgata caagtcttca ttctgaacga tttcggctac
     1321 acggtgaatg gtttgatcgt ataccgtctt ctcttaacca gcagtatcct tagttttaat
     1381 gactactcga taggttcctt tagaaccgtt atagtcatct agttttaaaa aagcattcca
     1441 aacattcaaa aatagttgga acttccctta ataaatccgt cactttcttt ttcaagatag
     1501 cccaagcttg ctcaatagga ttcaaatccg gtgaataagg tggtagaggt aagaaaaagt
     1561 gtttatcttg gatgcagagt tcatccaaaa tgttcttggg atgaaaacta gcattgccca
     1621 tgacaataac atgaggtgtc ttcaaagcag gtaggagttg cgttttgaac cactccacaa
     1681 agaaatcgct tgtcatgctt ttcttgtaaa tcatgggagc tataaactct ccgtctactt
     1741 gtcctgcaac aattgaagtt cgctcaaaac gacgtccgct aatcttttca tagactttct
     1801 cccctctagg agcccctgca taaggacgat agaggtagcg gttgattcct gtttcatcaa
     1861 tatatacgat tggtaaatct tttaggttat ccaaaatatc aagaaactca gcgactttct
     1921 ctgactcttg ttccttaaag atcgtcatct ttttttaaag tgaccttaat ctgctttaaa
     1981 gctgcccata ctgaaggaac agcacaatca aaatgtgccg caatttcccg taaaaaagca
     2041 tctggatgag cctctacaaa ggctttcaat tcttctaaag ggatcttacg ctttttgacg
     2101 actcgctttt tccgctctaa gttcctttgt tcacgtcttt cttttcccac gtgaagagag
     2161 ttctgacgcc aacaccaaaa aactttggcc gcctcgacat gtctgtgccc tcctttgatg
     2221 gaatctaatg ctccttgttt aaaatcagta ttatatgcca tagctttatt agaccatgct
     2281 tattttaaac taagcaacta tatcaatgtt ttgttatgag aagacttact ttttttactg
     2341 aaattgaatt tttcctagcc tcaacatcat ataaccccaa aattcaatct gacctggttt
     2401 gaagagatgt tcgaagcaga taaggtttta ctaaaactaa aaaaaatgat ataatcaaac
     2461 tgattaaatg ttttaaaaat aaaggagaat ttgaatgtct taccaagaaa attaccagaa
     2521 atgggttgat tttgtggagc ttcctgacta ccttcgtcaa gatttggaaa atatggacga
     2581 aaaaactaag gaagatgcct tctatacaaa tcttgaattt ggtactgcag gtatgcgtgg
     2641 cttggttggt gctggtacaa accgtatcaa catctacgtt gttcgccaag ctactgaagg
     2701 attggctcgt ttgattgagt caaaaggtgg aaacgagaaa gaacgcggtg tagcaattgc
     2761 ctacgatagc cgtcacttct cacctgagtt tgcctttgaa tctgcggcag ttcttgctaa
     2821 acacggcatc aaatcttacg tatttgaaag ccttcgtccg actccagaac tatcatttgc
     2881 agttcgtcat ctcaactgtt tcgcaggtat catggtcaca gccagccaca accctgctcc
     2941 atttaacggt tacaaggttt acggtgaaga cggtggacaa atgcctccac acgatgcgga
     3001 cgctttgact acttatatcc gtgcaatcga aaacccattt gcagttgaag ttgctgatgt
     3061 ggaaactgaa aaagcttctg gcttgattga agttatcggc gaagctgttg acgtagaata
     3121 ccttaaagag gttaaggacg taaacatcaa cccagccttg attgaagaat ttggtaaaga
     3181 catgaagatt gtctacacac cacttcatgg tactggtgaa atgttggctc gtcgtgctct
     3241 tgcccaagca ggatttgact ctgttcaagt tgttgaagcg caagcaactg ctgacccaga
     3301 cttctcaact gtaacatctc caaacccaga aagccaagca gcctttgccc ttgctgaaga
     3361 acttggtcgt caagttggtg cagatgttct tgtcgcaact gacccagacg ctgaccgtgt
     3421 tggtgttgaa gttcttcaaa aagatggtag ctacctcaac ctttcaggta accaaatcgg
     3481 tgctatcatg gctaaataca tcttggaagc tcacaaaaac gctggaactc ttcctgaaaa
     3541 tgccgctctc tgcaaatcta tcgtttcaac tgacttggta acgaagattg ctgaaagcta
     3601 cggcgcaact atgttcaacg tcttgacagg tttcaaattt atcgctgaaa aaatccaaga
     3661 attcgaagaa aaacacaacc acacttacat gatgggattt gaagaaagct tcggttactt
     3721 gattaaacca tttgtacgtg ataaagatgc catccaagcc gttcttgtcg ttgctgaact
     3781 tgctgcctac taccgttctc gtggtttgac acttgctgac ggtatcgaag aaatctataa
     3841 agaatatggc tactacgcag aaaaaacaat ctctgttact ctttcaggtg tcgatggtgc
     3901 tgaacaaatc aaagcgatta tggctaaatt ccgcaacaat gctccaaaag aatggaacgc
     3961 aacagctatc actgtcgtag aagacttcaa ggcacaaact gctactgttg ctgacggtac
     4021 tgttacaaac ttgacaactc ctccaagtga tgtgttgaaa tacacacttg ctgacggttc
     4081 atggattgcc gttcgccctt caggtacaga accaaaaatc aagttctaca ttgcagttgt
     4141 aggagaaacc aacgaagaat cacaagctaa gattgctaac atcgaagcag aaatcaatgc
     4201 atttgtaaaa taaagaccta taaaagatga gaccaaccaa cctcatcttt tttcgtatca
     4261 aatctaagca attttagaaa ctttatggca tactagactt atcaatgaaa gcgaggtaat
     4321 ctcatggaac aatttttaga taacatcaaa gaccttgaag tcactacagt tgtgcgtgcg
     4381 caagaagctc ttgataaaaa agaaactgca accttcttta tcggtcgcaa aacttgccct
     4441 tactgccgta aatttgcagg tacattgtca ggtgtcgtag ctgaaaccaa agctcacatt
     4501 tacttcatca atagtgaaga accaagccaa ctcaatgatt tgcaagcatt ccgctcacgc
     4561 tatggaatcc caactgtacc aggttttgtt catattacag atggacaaat caacgtccgt
     4621 tgcgactctt caatgtcagc acaagaaatc aaagatttcg caggattgta aaaaatcagc
     4681 taacaagtct taaaatcaca aaaacgcata atgtaaggtg caaaaacctt gatattatgc
     4741 gttttattgt tcctaaaaca gttacatcag catttcatta cagaacattt taattttgga
     4801 agtcaaatca atttttaaca atgttttaga aatcacagtg ggctattcca tattaaatta
     4861 tccagattca atcgctatta tcgttttcct agattacaaa aaaactgcgt tttgctaatc
     4921 aaaacgtagt ctcagccact attttatctt actgtccttc ttttacttct ttggttgcta
     4981 catcttctcc aaaccatttt tggctgattt cttggaactt gccgtccttg taaagactag
     5041 aaaaagcttc atttatcttc ttaaccaagg ttgtatcttc cttacgggct ccaaccgcaa
     5101 aagcttctgt ttctagtcca actgtaaaga cattataatc gtttaaaaca ccttctgctt
     5161 ctaaataata gtttgcatag acacggtcaa tcaatagacc atcaattcga tcgtttttca
     5221 aatcaatcaa ggcttcatta aaggtttggt attgattcgc ttccttatta gcgacaatat
     5281 tcttcaaaat ttctggattt gcttcaaagt ccgcataacc agatgaacca gcttgagctc
     5341 ctaatgtctt tccagtcata tcctttgcag tcgtgatacc agatgatttc ttcgtaacca
     5401 atacctgctc attcttcata tatgagttac tgaaagccac cttttcacgg cgttcgtctg
     5461 tagcggaata gccattccaa atcagatcaa tcgttccttt tgtcaattca gcttctttca
     5521 aatcccaatc aatcggttgc caatttaccg tgattccgta tttttcaaaa acagctgtag
     5581 ctaaatcaat atcaaatcct gcataagaac catctttctg agcaaatccc attggaacaa
     5641 aagtactatc aaatccaata gtaatagact tgttagactg gtactttgac caattatctc
     5701 cactagtttc gctagaattt ttcccacaag ctactaagaa caaagcagtc atcagactga
     5761 ctaatacaag catccatttt ttcatccatt tttcctccta tttaggttct actttcaata
     5821 atacatctgc gatattttca gcaaactgca aatcatgggt aaccacaatc tgggtcatcc
     5881 caagttccct attttgcaag attagcttct ccacttccaa acgtaattct ggatccaggg
     5941 cagaagttgg ttcatcgtag ccaatgattt ctgggtcaat catcatagca cgcgccaaag
     6001 ccacccgctg cttttgccca ccagatagtg agaaaggata ggcctctgcg tgtcctccta
     6061 gtcctaactg ttccaagagt ccactcgcct tcttctcagc ctcttcctgc ttcattccca
     6121 tggtcttcac aggcgataag gtcaaattgt ccagaactga taaatgaggg aacagttgaa
     6181 aatcttggaa tacaaatccc agtagattgc gcttctgcaa ttcatccagc tctaaaggtt
     6241 gtccattata aaagatttgc cctgaatcaa tggtttcaag acctgcaagc atacgtaaaa
     6301 gagttgtctt acctccacca gaaggtccaa cgatagccag gatttgcttt tcaggaatac
     6361 ttagactgaa attagacagg atttgtttgt ctccaaagac tttattgata tttcgtaatt
     6421 ctaacatggc agcctcctat ctataataac tatacttctt ctcaactttt ttggaaataa
     6481 ttgtcacaat cccaatcaaa atcaaataaa tggctcctgc caagaacata ggaactagac
     6541 tagcatcgcg gttagcagct gttcgactag ccaagataag gtctgaaatt ccgagagcat
     6601 agaccaaaga agtatccttg accaaactca taacttcatt aaagacacta ggaagaacga
     6661 tcttggtcac ttggggcaag ataatatagc gcactctgtc aaaagggcta aacttcaaga
     6721 ccttggcggc ctcatactgt cctcttggaa tagtgtcaat tcccccacgg aaaatttctg
     6781 caaagtaagc tgcatagttg agaacaaagg caataatagc tgcaggaagg cggtctaaac
     6841 gaatcccaat acttgggagc acataataga taaaaatcag ttgcaagagt aagggggttc
     6901 ctcgcataac ccagatgtaa atgttaatca gataatggag gggcttccaa tggacttgca
     6961 aggcaaaggc aatcaaaacg cccaagggaa tcgaaaatag caagaccagt gcaaagacct
     7021 gtacagtcgt gctcgcacca ttcagtaaac tcggtaatat ctcaaataaa taagacatac
     7081 tgcacctcct aaaagtaatt gttcctatta tagcatgaat aaacaagatt accaagtatt
     7141 tttgtaaaaa gattctacca tatacaaata aaaaccgtag ctatcaaaag agataaacta
     7201 cagttctata tgtttaaaca ttcttacaat ctctcaaaca gttcttgcat ttgcacatca
     7261 tctggaacca gttttaagta agtgtgagca tggacttttg cttcttcaaa atgtcccaat
     7321 tcacgcaaga gatagatata gtgttccaga aattctggat tgtccttcaa atctcctatc
     7381 aactcttgat aatgctcata agcagtatcc aaatcgtcca tttcttgata agaacgagca
     7441 atcatccact tggtcaaaag attttctgac tcctcactct gcaagtctag aatatcctca
     7501 taacgctcct gctccagata aatagtggct aaacgaagca agatttcttc tgtatcctca
     7561 gcgtcttctt ttgcagtaag gagataattt tctgcaccac tagcatcatg caattcataa
     7621 gaaaattgtg aagcagctag caagaggcga gtttcaaagg gatttttctc taatccttgc
     7681 ttagcgatac gcagggcttc ttgaacttga tgttccttat gtaaagcctg actgtaccca
     7741 tactcatagc cttcaaagtc aggagaaatg gtatcaagct gcttaaagta gagggtggct
     7801 ttttgatatt cttcttgatc aaaataaaga ctggccaact caaaagctgt taagtcatcg
     7861 tattctaact ccagggcttt ttctaaaaac tcagtagccg tttcaaattt ccctaactga
     7921 gcataggcaa agccaattcg ttgataggtg gaaatgcccg tttgctcata aatcgagcga
     7981 ttatctaact gggcataggc ttgaatagcc gcttggtaat tttccaactc actatccaac
     8041 tctgccaaac ccaatatcaa gagagaatcc tctgagtagg tcaaggcctc caataatttc
     8101 tcacgtgcca catctgtcaa accttccagc tggtaaaggt ctgccttcag agccaaagac
     8161 gagacatacc agtcactgtc agcttggatt tcctcaagat aggtaaaggc ttcttctatt
     8221 tgaccatcct cgctagcaat tgcagctaga ttaagatgaa cctctggaaa atcctctaca
     8281 attttcaggt aaatttcctt ggcctgagga tagaaaccaa tcccttcaag ataagttgcc
     8341 aactcataca gaagatcact tgaatcattt tctaaagctt tggcgaaata atgctcagcc
     8401 ttagttaaat cttgctcctc caaagcctgt aacatctgtt gactattgtt cactcttgac
     8461 ttcctcaccc tctaattcat atagaccact gactacctta taccattcga aaatggctga
     8521 aatgacaacc ttagcagagg cataaaccgg aataccaagt aaaactcccc agataccaaa
     8581 catagatcct gaagttaaca aaacaaagag aacattaata gggtggatgt ttaattgact
     8641 tcccaaaatc aatggagaga caaaacggcc ttcaatagtt tgttctacga taaagacaat
     8701 cactactttc aaaagcatga ctggaccagc aatcaaaccc aatactagag caggaagcat
     8761 ggctagaaag ctaccaagat aagggaccag atttaaaata ccagcagtaa cccccagcgt
     8821 aaccgcatag cgtagaccaa taatcttgaa gaagatgata aacattactg ctacaataat
     8881 agccactgtc acttgccctc gaacatagtt ggacaactgt tgattcacat ctgataaaac
     8941 ttgtccaaca ggttccttca attttcttgg aatgaattgg gtcaaatagt tacgcaagcc
     9001 tttcccatca cgcaagagat aaaagagcat gaaaggaacg ataatcaagg caacaatcac
     9061 ttgagaagct ccgctaataa aggcactcac ccagttgact gcctgagatg aaaccttact
     9121 tgccaaaact gtagcctggc tagaaaaatt ggtcaaaact tgctctaatt gaggtctgaa
     9181 atcatctggc aggtgctggg ctaccaatcc attaacaatc ctatctatat cttctaagta
     9241 aacaggaacg tttcttgcaa aggtcaaaac ctgacgttgc agatttggaa tggcgactgc
     9301 caagccccaa atgataaaga gagcgatgat aacaaagaca atagtgatag ctataacacg
     9361 attaacctta tgcttctcca tccaatcaac aataggattc aacaaataat ataacaaacc
     9421 agacaaaatg actggcaaca tcacaactgc taaaaagtct aaaacaggtg aaaatagaaa
     9481 actaatctta cttaaaataa aaagattcag tcccaataat aaggttacta aaaataccgt
     9541 aattgccttg ttatctaaaa accacttgaa aaaccaagat aggctaaaat gtttctcttt
     9601 ttgctccata aatacttcct ttctattgtt ctctcattat accatttttg aaacaaaata
     9661 actctttttt aaagtgctta catctaattg gatatcttta atttacttgt ttttgtgata
     9721 taatagtctt atctttacac agaggtatag taatgaaaga aactgtttat tttggaactt
     9781 atacacgtcg tacttctcaa gggatttaca aggcagactt tgatacagaa actggtcagc
     9841 tttcaaatct agaacttttt gcagctgagc caagtccaac ctaccttgcc tttgaccagc
     9901 accaacattt atacactgtt ggtagccaag acgataaggg gggaattgca gcctatcaaa
     9961 ctgacgggac tgtgttaaat catgttgttg aagaaggagc tccccactgt tatgttgctg
    10021 tcgatgaaaa gcgtgatttg gtttacgcag ccaactatca caagggacaa gtccttgttt
    10081 ataaacgcca ggaagatggt agtcttctac ttagtgatat ggatcaacac agtggccaag
    10141 gtccacatga aaatcaagct tccccccatg ttcactatac agatttaaca cctgaccact
    10201 atctagtgac ctgcgacttg ggaactgacc aagtcatcac ctatgacctc gatcaagaag
    10261 gaaaattatc taagctctat acctatcaca gcaagccagg agcaggctca cgccatatca
    10321 ttttccataa ccactataaa atcgcttatc tcatttgtga actcaatagt actatcgaag
    10381 ttttaatcta cgatggcgtt ggcgaatttg aacgtatgca ggtcatttca actttaccgg
    10441 aagcttacga aggctttaat ggaaccgctg ctattcatct ctctaaagac ggtaaatacc
    10501 tctacgcttc taaccgtggc catgattcta tcgcagtata taccatcctt gcggacggta
    10561 gcttagagtt attagaaatc gttccaacgc atggtcagac tccacgtgat tttgatttga
    10621 cacccgacca aaaatttctc attgttgtcc atcaagactc tgacaatgca actgtcttta
    10681 aacgtaattg tgacaatggt cgtctagcag aactctccaa cgacttccat gttcccgaag
    10741 cagtctgcat ccgttttgct ccttaaaaca ccataaaaaa tgaacttggt attttcaagt
    10801 tcattttttc ttatagtcta tttccgacat taatacggtt aatagcacgt tgcaaagcaa
    10861 tcttagcacg acgttcttgg tcaatcaaat gtttgtcttg tgcttcttca attgcacgtt
    10921 ctgcacgaag tttggcacgt tctgcacgac tgatatcgat atcacgagca cgttctgcag
    10981 agtcagcgac gattgtgatc atatcattgg caatttcaat aacaccaccg tttactgcaa
    11041 tccagttcac ttgatcttta tcatcgatac gttttacctt tacttcatca actgctaaaa
    11101 ccgcaatcat attttcatgt cgtggcaaga tccccatctc accatccaga gttcgaaccg
    11161 atacatagct ggcatggtga tcatagacga gaccatctgg tgtcacgatc tggacagtta
    11221 actgagccat agttcacctc ttaaaatccc attttttcag cttttgcaat cacatcttcg
    11281 atagaaccta caccacggaa ggcatcttct ggcaagtggt cgtatttacc atcaaggatt
    11341 tccttaaagc cacgtacagt ttcagcaact ggaacataag aacctggctg accagtaaat
    11401 tgttccgcaa cattgaagtt ttgtgacaag aagaactgga tacgacgggc gcgagcaacc
    11461 aaggtctttt cttcatcaga aagttcatcc ataccaagga tagcaatgat atcttgcaat
    11521 tcatggtaac gttgaaggac acgttttact tcagcagcaa ctgcatagtg ctcttctcca
    11581 acgatttcag gtgccaaggc acgtgagctt gaagcaagtg ggtcaacggc tgggtagata
    11641 cccaattgta ccaacttacg ttccaagttt gttgttgaat ccaagtgagc gaaggctgtt
    11701 gctggcgctg ggtcagtata gtcatccgct ggcacataga tagcctggat agaggttaca
    11761 gaacccttct tggttgatgt gatacgttct tgcaattgac ccatttccgt agcaagtgtt
    11821 ggttggtaac caacggctga tggcatacga cccaaaaggg cagatacttc tgaaccagcc
    11881 tgagtgaaac ggaagatatt atcgataaag agaagcacgt cttggccttc cacatcacgg
    11941 aagtattcag cgattgtcaa accagtaagg gcaacacgca tacgtgctcc tggtggctca
    12001 ttcatctgac caaagaccat ggctgttttc tcgataacgc ctgattcttt catttcccag
    12061 taaaggtcat tcccctcacg agtacgttcc ccaacaccag caaatactga aataccaccg
    12121 tgctcttggg caatgttgtg aatcaattct tggattaaga cagttttacc aactccggca
    12181 ccaccgaaaa gtccaacttt accaccttta aggtaagggg caagaaggtc aataaccttg
    12241 atccctgttt caaggatttc agaagaggta gacaactcat caaaagttgg agctttttta
    12301 tgaattggct gacgctctgc gtcttctgta aaaggagctt ccaagtcaat ggtatctccc
    12361 aaaacgttga agacacgtcc caaagtttct ttacctactg gtacagagat tggacgacct
    12421 gtgtccaata cttccattcc acgagtcaac ccatctgttg attccatggc gatagtacga
    12481 accataccat ctcctaactc caaggctact tcaaggacga tttttgtttt tctttcgtca
    12541 tttttgtaga cgacaagtgc attgttaatc tcaggaagtt tttcccctgc tgcaaacaaa
    12601 acgtctacaa cgggaccgat aacctgagca attttacctg aactcatctc cttctcctat
    12661 tctatataag atactgtcgg ttcctagctc aactaggtcc taagttcatt ttcatacgag
    12721 ctggactaga gcctattcta aggcactagc acctgctacg atttctgtaa tttcttgtgt
    12781 aatcgccgcc tgtctggcac ggttatactg aattgtcaaa tcattgatga ctttcttagc
    12841 attatctgtc gctgtttgca tggctgtcat acccgcagca ttctcagctg tcttggcatc
    12901 tataatggca ccgtaaatca tactttctgc aaactgaggc aacaactgct ccagaatttc
    12961 ttctcggctg gtttccaatt caaaagtcaa gctgtactct tcatccgctt catttggatc
    13021 caagtcaaca atcggaagca tttgttccac acgcatttga ctggttagcg tattgacatg
    13081 gtggttgtag caaacataaa gctcatcaaa gagttcattt tggtacattt caacagtttt
    13141 tgaaataatc ttacgaactt gatcaaagct aggttggtct gccaagccac gtaattcata
    13201 aagtggttga ataccgcgag ccttaaagaa atcagctccc atcccaccga tacagatcat
    13261 ttcaaaacct ttaccgtctg ggtggtattc ttctttcaac tccataacag ctttcaaaat
    13321 agaggaatta taacctccaa ccaaaccgcg gtctgaagtg ataacgatat agcctgtctt
    13381 cttcacagaa cggctaatca acatcggatt agttgaagca ccagctccat taccatgaag
    13441 gatatctgtc aaaagtttac gcactttctg agcgtaaact tggaagttgc gagcagcttc
    13501 ttcagagcga cctagcttag cagccgatac catttgcatg gcattagtga tttgactcgt
    13561 attttttgtt gaggcgattt ttgttttaat atcatttaga gatactgcca tctgacacct
    13621 ctattcttat tggaagctag attgattgag aaactctgta atcgcagcat ccaagactgc
    13681 ttcttctggc aagtcttttg tatcacgaat ggtttccaaa atctctggat gttgagcatc
    13741 aaagaaggca tggaactctt cctcgaaacg aacaatatca tctactggaa cagtatccaa
    13801 gaaaccatgt atcaaagcat aaagaatggt tacttgtttc tcaacaggta atggtttgtg
    13861 aacaggttgt ttcaagacct caacggtacg acgtccacgg ttcaacttag cctgtgttgc
    13921 tgcgtccaag tcagaaccaa acttagtaaa ggcttccaac tcacggtatg aagcaaggtc
    13981 gatacgaagt gtaccagcaa ccttcttcat ggctttgatt tgtgcagaac cacctacacg
    14041 agatacagat gaacccgcat cgatggctgg acgaatacct gcattgaaga ggccatcgcc
    14101 aaggaagatt tgtccatcag tgatagaaat cacgttggtt gcgatatagg ctgagatatc
    14161 tcctgcttgt gtctcgataa atggtagggc tgtaattgat ccaccaccaa gttcatcaga
    14221 aactttagct gagcgctcaa gcaaacggct gtggagatag aaaacatccc ctgggaaggc
    14281 ttcacgacct ggaggacgac gaagcaagag cgacagttca cgataagcta ccgcttgttt
    14341 tgatagatca tcgtatacaa tcaaaacatg cttaccttga tacataaatt cttccgccat
    14401 agcgacccca gtataaggag ctaggaagag caatggagat ggttgtgaag cagaggctgt
    14461 cacaacgatt gtgtagtcca aggcaccgta ctgacgaagt gtttctactt gcgtacgaac
    14521 tgttgattct ttttgtccaa tcgcgacgta gatacagatc atatcttgat ctttttggtt
    14581 caagattgta tcaatcgcaa tggttgtttt ccctgtctga cggtcaccga taatcaactc
    14641 acgttgacca cgaccaatcg gtacaagggc gtcaatagct ttcaaaccag tttgcaatgg
    14701 ttctgaaaca gacttacgtt gcataacacc aggagctggt gcttctactg gacgagtttt
    14761 atcagtgtgg atttctccaa gaccgtcaac tggacgacca agcggatcca caacacgacc
    14821 aatcagactt tcacctacag ggacttccat gattttccct gtacggcgga ttgtatcgcc
    14881 ttcacggata tctgtaaagt cacctaggat gataatacca acgtctgttg actccaagtt
    14941 ttgagccata ccataagagc cgttttcaaa attcaacaac tctccactca tgacattttc
    15001 aaggccgtga gcacgcgcga taccgtcccc gatataggtt acaacacctg tttcagtcac
    15061 atcaaaattg ggtttgaaat tttcaatttg ttgcttaatt aaagcgctga tttcttgtgc
    15121 gttaattgcc aaaagaacac cactttctat ttcaaatttt ctttaacaac tttaagttgt
    15181 tgtttaatac tcacatcaat tgtcttgtga ttggcaaaaa tgacaaaacc accaatgaga
    15241 ctttcatcga tttgttcttt tacactcctt actttcagag acattttttt ctcaatcaaa
    15301 gggagcaaac gagtcttctg ttcatcagtt agaggatgag cagacgtaat cgtcacttca
    15361 aatcgatttg tttctttttc aagtcggttc aagcaatcta caagcacatc ataaaaaaga
    15421 tttgctctgt gattgtaggc cagaacctgg ataaagtttt gtaataaagg cgacacagaa
    15481 tcttggaaaa aagcaattgt tttttcctta tccgactcgt ctactgccac ttgttttaaa
    15541 aaagaaggca gacctgtttt ttcaacaact tgcttgattt gagtcaagtc tgaaaagata
    15601 cggtcttctt ctcctttttc aagtaccaat tggacaaaag gcatgctgta tttttcaatt
    15661 acctttactg ttttcttgtc cattaagctt ctcctagctg atcgatatac tgatcaatga
    15721 gtgctttatg ggcatgactg tcaaggtttt gtgagatgat tttaccagct aagctgatgg
    15781 tcagatctgc gacctcaccc ttaacactct gtaaagcttc tactttattt tgagcaattt
    15841 cttgattggc tttttctttt aagtgtcctg cttctagttt agcatctgct aagatattag
    15901 ccttactttg ctcagctgtt tcctttgcat tttcaatgat tgtcttagct tctttacggc
    15961 taccagccaa ttcatcttcg cgtttttgag ccaatacttc tgctttttga cgggcttctt
    16021 cagctctgtc aatatctgaa gcaatttttt cagctctttc ttcgaaaatg cctgtaatat
    16081 tagaccatgc aaatttttta atcaagacta gcaaaagaat aaaagagcca gtgattaaaa
    16141 taaaattacc aattaattca cctactgtta cgtgcatcag ttactccttt ctattcctct
    16201 tcaatattaa tcttattccc taaatacaca gatgtcaaaa gagtaaaaac ataagcttgg
    16261 atgcaggaaa taaagacaga aaatgcagtc caagccaaat tagctccaaa ggctactgga
    16321 taccaataaa tagcttggtg ggaaagaaga agtaacaaac tcgtcatgac ctctcctgca
    16381 aagatattcc caaaaatccg caaagccaaa gataagaagt ttgtaaattc ttccaagata
    16441 ttcatcggta tgacaaaaac aggactcata aaagatttta tacttttttt aaatccacga
    16501 cgacgaacgc tttctatatg tgtcaacaaa atgacaagaa aagataaggt taagtcatac
    16561 tgtaaattag cggttggcga actccaccag ttagtcccat cgatcgtttg aagctttgtc
    16621 attaagccaa ggttattggc aatcaccatg aaaaggaata aacaaaggaa aaagagtgaa
    16681 taatctttca tgtagcgcga accaatgtta ggttctgtaa atccaataac aaagtcatag
    16741 acatactcaa gtacattttg ctttcctttg ggtttcaagg tcatattgcg gcttgcccaa
    16801 taaataaaga caaaaataac tcccacaatc aacaaagtca tggctaacat agtcagattg
    16861 aagataacag gaccaataga gatgattgga ttaatacttt cttccatcta aaatcctccc
    16921 ttttcttctc gttccatgta tttatttgat aataaatgag aagacaagag ttacaaagaa
    16981 agttccttca ataaaggcaa aacctaaaaa catcaaacta cgaaactcag aaagcatatc
    17041 tggttggcgt gctactgatt taaacagtcc attcatcaat aaaccttcac cgacagatac
    17101 gcccatacag gcaatacata agcctaaaaa tgttaaattc ataacaaatt ctcctttaaa
    17161 ataaaattta cttacttagt gtagtcctaa aatttaaatt tgtcaacttt taaccgctat
    17221 tggaagcgtt taataaaaat tatttccatt ttgctaaatt tcaagttcaa gttagccatc
    17281 ca
//
LOCUS       DAVBBO010000048        16132 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ST1
            SAMEA2066453-rid20184263.denovo.048, whole genome shotgun sequence.
ACCESSION   DAVBBO010000048 DAVBBO010000000
VERSION     DAVBBO010000048.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2066453
            Sequence Read Archive: ERR351777
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 16132)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 16132)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980402.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980402.1
            Genome Coverage       :: 176x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:17:33
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,141
            CDSs (total)                      :: 2,104
            Genes (coding)                    :: 1,953
            CDSs (with protein)               :: 1,953
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 16S)
            partial rRNAs                     :: 1 (23S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 151
            CDSs (without protein)            :: 151
            Pseudo Genes (ambiguous residues) :: 0 of 151
            Pseudo Genes (frameshifted)       :: 73 of 151
            Pseudo Genes (incomplete)         :: 76 of 151
            Pseudo Genes (internal stop)      :: 40 of 151
            Pseudo Genes (multiple problems)  :: 32 of 151
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..16132
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2066453-rid20184263.denovo.048"
                     /strain="ST1"
                     /db_xref="taxon:1313"
     gene            145..6831
                     /locus_tag="VQU30_001620"
     CDS             145..6831
                     /locus_tag="VQU30_001620"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001865153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Ig-like domain-containing protein"
                     /protein_id="HET2447695.1"
                     /translation="MGKGHWNRKRVYSIRKFAVGACSVMIGTCAVLLGGNIAGESVVY
                     ADETLITHTVEKPKEEKMIVEEKADKALETKNVVERTEQSEPSSTEAIASEKKEDEAV
                     TPKEEKVSAKPEEKAPRIESQTSNQEKPLKEDAKAVTNEEVNQMIEDRKVDFNQNWYF
                     KLNANSKEAIKPDVDVSTWKKLDLPYDWSIFNDFDHESPAQNEGGQLNGGEAWYRKTF
                     KLDEKDLKKNVRLTFDGVYMDSQVYVNGQLVGHYPNGYNQFSYDITKYLHKDGRENVI
                     AVHAVNKQPSSRWYSGSGIYRDVTLQVTDKVHVEKNGTTILTPKLEEQQHGKVETHVT
                     SKIVNTDDKDHELVAEYQIVERGGHAVTGLVRTASRTLKAHESTSLDAILEVERPKLW
                     TVLNDKPALYELITRVYRDGQLVDAKKDLFGYRYYHWTPNEGFSLNGERIKFHGVSLH
                     HDHGALGAEENYKAEYRRLKQMKEMGVNSIRTTHNPASEQTLQIAAELGLLVQEEAFD
                     TWYGGKKPYDYGRFFEKDATHPEARKGEKWSDFDLRTMVERGKNNPAIFMWSIGNEIG
                     EANGDAHSLATVKRLVKVIKDVDKTRYVTMGADKFRFGNGSGGHEKIADELDAVGFNY
                     SEDNYKALRAKHPKWLIYGSETSSATRTRGSYYRPERELKHSNGPERNYEQSDYGNDR
                     VGWGKTATASWTFDRDNAGYAGQFIWTGTDYIGEPTPWHNQNQTPVKSSYFGIVDTAG
                     IPKHDFYLYQSQWVSVKKKPMVHLLPHWNWENKELASKVADSEGKIPVRAYSNASSVE
                     LFLNGKSLGFKTFNKKQTSDGRTYQEGANANELYLEWKVAYQPGTLEAIARDESGKEI
                     ARDKITTAGKPAAVRLIKEDHAIAADGKDLTYIYYEIVDSQGNVVPTANNLVRFQLHG
                     QGQLVGVDNGEQASRERYKAQADGSWIRKAFNGKGVAIVKSTEQAGKFTLTAHSDLLK
                     SNQVTVFTGKKEGQEKTVLGTEVARVRTLIGKEPKMPKTVGFVYSDGSREKLPVTWSQ
                     VDVSQAGVVTVKGTANGREVEAHVEVLAIAKELPTVKRIAPNTDLNSVDKSVSYVLTD
                     GSVQEYEVDSWEITEVDKAKLSVAGSRIQMTGQLAGETIHATLVVEEGNAAAPVVPTV
                     TVGGEAVTGLTSRQPMQYRTLSYGAQLPEVTASAENADVTVLQASAANGMRASIFIQP
                     KDGGPLQTYAIQFLEEAPKIAHLSLQVEKADSLKEDQTVKLSVRAHYQDGTQAVLPAD
                     KVTFSTSGEGEVAIRKGMLELHKPGAVTLKAEYEGAKGQVELTIQANTEKKIAQSIRP
                     VNVVTDLHQKPTLPTTVTVEYDKGFPKAHKVTWQAIPKEKLDSYQTFEVLGKVEGIDL
                     EARAKVSVEGIVSVEEVSVTTPIAEAPQLPESVRTYDSNGHVSSAKVAWDAIRIEQYA
                     KEGVFTVNGRLEDTQLTTKLHVRVSAQTEQGANISDQWTGSELPLAFASDSNPSDPVS
                     NVNDKLISYNNQPANRWTNWNRTNPEASVGVLFGDSGILSKRSVDNLSVGFHEDHGVG
                     APKSYVIEYYVGKTVPTAPKNPSFVGNEDHVFNDSANWKPVTNLKAPAQLKAGEMNHF
                     SFDKVETYAVRIRMVKADNKRGTSITEVQIFAKQVAAAKQGQIRIQVDGKDLANFNPD
                     LTDYYLESVDGKVPAVTASVSNNGLATVVPSVREGEPVRVIAKAENGDILGEYRLHFT
                     KDKNLLSHKPVAAVKQARLLQVGQALELPTKVPVYFTGKDGYETKDLTVEWEEVPAEN
                     LTKAGQFTVRGHVLGSDLVAEVTVRVTDKLGEALSDNPNYDENSNQAFASATNDIDKN
                     SHDRVDYLNDGDHSENRRWTNWSPTPSSNPEVSAGVIFRENGKIVERTVAQAKLRFFA
                     DSGTDAPTKLVLERYVGPEFEVPTYYSNYQAYDADHPFNNPENWEAVPYRADKDIAAG
                     DEINVTFKAVKAKAMRWRMERKADKSGVAMIEMTFLAPSELPQESTQSKILVDGKELA
                     DFAENRQDYQITYKGQRPKVSVEENNQVASTVVDSGEDSLPVLVRLVSESGKQVKEYR
                     IQLTKEKPVSAVQEDLPKLEFVEKDLAYKTVEKKDSTLYLGETRVEQEGKTGKERIFT
                     AINPDGSKEEKLREVVEAPTDRIVLVGTKPVAQEAKKPQVSEKADTKPIDSSEASQTN
                     KAQLPNTGSAASQAAVAAGLALLGLSAGLVVTKGKKED"
     gene            complement(7079..7935)
                     /locus_tag="VQU30_001621"
                     /pseudo
     CDS             complement(7079..7935)
                     /locus_tag="VQU30_001621"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006270419.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(8146..8505)
                     /locus_tag="VQU30_001622"
     CDS             complement(8146..8505)
                     /locus_tag="VQU30_001622"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004249826.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3397 domain-containing protein"
                     /protein_id="HET2447696.1"
                     /translation="MGMILMKLASILLLILTLVVCIILTKLFRLKKLGRNFADLAFPV
                     LVFEYYLITAKTFTHNFLPRLGLALSILAIILVFFFLLKKRSFYYPKFIKFFWRAGFL
                     LTLIMYIEMIVELFLMK"
     gene            8597..9553
                     /locus_tag="VQU30_001623"
                     /pseudo
     CDS             8597..9553
                     /locus_tag="VQU30_001623"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002881980.1"
                     /note="This family includes YhcC from E. coli K-12, an
                     uncharacterized radical SAM protein.; internal stop;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01212 family radical SAM protein"
     gene            9537..10094
                     /locus_tag="VQU30_001624"
     CDS             9537..10094
                     /locus_tag="VQU30_001624"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000828405.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HET2447697.1"
                     /translation="MKRPLEMAHDFLAEVVTKEDVVVDATMGNGHDTLFLAKLAKQVY
                     AFDIQKQALEKTQERLHQADLTNAQLILQGHETLDQFVIKAKAGIFNLGYLPSADKSV
                     ITRPQTTIEALEKLCGLLVKGGRIAIMIYYGHEGGDLERDAVLDFVIQLNQQEYTAAI
                     YRTLNQVNNPPFLVMIEKLERYRHG"
     gene            10087..10341
                     /locus_tag="VQU30_001625"
     CDS             10087..10341
                     /locus_tag="VQU30_001625"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000361102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2447698.1"
                     /translation="MDKQYLHEKLDAMRQNFVESTHHERSVGVLDQAHMSKKMLKIKK
                     KLVALEMERCQRKIEHKDCSKIDQKIKEQKEIFESCCKKD"
     gene            10353..12407
                     /locus_tag="VQU30_001626"
     CDS             10353..12407
                     /locus_tag="VQU30_001626"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000421632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation:proton antiporter"
                     /protein_id="HET2447699.1"
                     /translation="MELLIYLILFLLVLIVSSTTNKLLPFLPLPLVQILLGIVIGLFL
                     PNTDFHLNTELFLALVIGPLLFREAEEADVTAILKHWRIIVYLIFPVIFISTLSLGGL
                     AHLLWFSLPLAACLAVGAALGPTDLVAFASLSERFSFPKRVSNILKGEGLLNDASGLV
                     AFQVALTAWTTGAFSLGQASSSLIFSILGGFLIGFLTAMTNRFLHTFLLSVRATDIAS
                     ELLLELSLPLVTFFLAEEVHVSGIIAVVVAGILKASRFKKITLLEAQVDTVTETVWHT
                     VTFMLNGSVFVILGMELEMIAEPILTNPIYNPLLLLLSLIALTFVLFVIRFIMIYGYY
                     AYRTRRLKKKLNKYMKDMFLLTFSGVKGTVSIATILLIPSNLEQEYPLLLFLVAGVTL
                     VSFLTGLLVLPHLSDEEEESKDYLMHIAILNEVTLELEKELEDTRNKLPLYAAIDNYH
                     GRIENLILSQENQDDQEDWAALKLLILSIESDGLEQAYEEGNISNRAYRVYQRYLKNI
                     EQGINRKLASRLTYYFLVSLRILRFLLHEVFTLGKTFRSWKDKEQSRLRALDYDQIAE
                     LYLANTEMIIESLENLKGVYRRSLISFMQESRLRETAIISSGAFVERVINRVKPNNID
                     EMLRGYYLERKLIFEYEEKRLITTKYAKKLRQNVNNLENYSLKEAANTLPYDMVELVR
                     RN"
     gene            12586..13446
                     /locus_tag="VQU30_001627"
     CDS             12586..13446
                     /locus_tag="VQU30_001627"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YihY/virulence factor BrkB family protein"
                     /protein_id="HET2447700.1"
                     /translation="MKKWWKELIDKPLLKAFLHYYQASDSELTSVAVAYYWLISIFPL
                     LLVVVNILPYFQIPVGEFLCFMKDVLPPSLYEGVEKIAREVLTQPSTGLLSFSVLSAL
                     WSFSKSMNFLQKAFNKAYGVEKSRGLISHQMLSLLVSFGLQLLFAFALFLILFGQMIL
                     ALLAHYWTKDGIIYQALQGLAGPLIYALLFAILVMLYYFLPNLSNRKISYTLPGSAFV
                     LLVILGLLTLFSSYLNYYVHHLVDVRILGSVLLVVMMFWFILIAKIVILGAVINASMQ
                     SLKDPVFKKD"
     gene            13657..14367
                     /gene="ccdA2"
                     /locus_tag="VQU30_001628"
     CDS             13657..14367
                     /gene="ccdA2"
                     /locus_tag="VQU30_001628"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000509848.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiol-disulfide oxidoreductase-associated
                     membrane protein CcdA2"
                     /protein_id="HET2447701.1"
                     /translation="MGHIFFFLSVFLAGILSFFSPCILPLLPVYTGVLLDDKDGAQAS
                     SGKFSISVTSLLRTLAFIAGISFIFILLGYGAGFLGDLLYASWFQYLTGAIIILLGLH
                     QMEILHFKGLYKEKRLQLQGQGQNGKGYSQAFLLGLTFSFAWTPCVGPVLGSVLALAA
                     SGGSGAWQGAGLMLVYTLGLALPFLLLALTSSYVLKHFRKLHPYLGILKKVGGFLIIV
                     MGLLVLFGNASILSQLFE"
     gene            14387..14953
                     /locus_tag="VQU30_001629"
     CDS             14387..14953
                     /locus_tag="VQU30_001629"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000759281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="redoxin family protein"
                     /protein_id="HET2447702.1"
                     /translation="MKKWQTCVLGAGSLLCLTACSGKSVTSEHQTKDEMKTEQTASKT
                     SAAKGKEVADFELMGVDGKTYRLSDYKGKKVYLKFWASWCSICLASLPDTDEIAKEAG
                     DDYVVLTVVSPGHKGEQSEADFKNWYKGLDYKNLPVLVDPSGKLLETYGVRSYPTQAF
                     IDKEGKLVKTHPGFMEKDAILQTLKELA"
     gene            14964..16076
                     /gene="msrB"
                     /locus_tag="VQU30_001630"
     CDS             14964..16076
                     /gene="msrB"
                     /locus_tag="VQU30_001630"
                     /EC_number="1.8.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730371.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-methionine (R)-S-oxide reductase MsrB"
                     /protein_id="HET2447703.1"
                     /translation="MNDKLKIFLLLGVFFLAITGFYVLLIRNAGQTDASQIEKAAVSQ
                     GGKAVKKTEISKDADLHEIYLAGGCFWGVEEYFSRVPGVTDAVSGYANGRGETTKYEL
                     INQTGHAETVHVTYDAKQISLKEILLHYFRIINPTSKNKQGNDVGTQYRTGVYYTDDK
                     DLEVINQVFDEVAKKYDQPLAVEKENLKNFVVAEDYHQDYLKKNPNGYCHINVNQAAY
                     PVIDASKYPKPSDEELKKTLSPEEYAVTQENQTERAFSNRYWDKFESGIYVDIATGEP
                     LFSSKDKFESGCGWPSFTQPISPDVVTYKEDKSYNMTRMEVRSRVGDSHLGHVFTDGP
                     QDKGGLRYCINSLSIRFIPKDQMEEKGYAYLLDYVD"
BASE COUNT         4901 a         3052 c         3565 g         4614 t
ORIGIN      
        1 catatctacg gcaaggcgac actgacgaag tttgaattgg attttcgcag agtgtaaatt
       61 gttgaaacta ggttgtcata ccatgtatac cacttgggct ttggtagtag ctaactgcac
      121 taaatataat ataaggaggg ttttatgggg aaaggccatt ggaatcggaa aagagtttat
      181 agcattcgta agtttgctgt gggagcttgc tcagtaatga ttgggacttg tgcagttcta
      241 ttaggaggaa atatagctgg agaatctgta gtttatgcgg atgaaacact tattactcat
      301 actgttgaga aacctaaaga ggaaaaaatg atagtagaag aaaaggctga taaagctttg
      361 gaaactaaaa atgtagttga aaggacagaa caaagtgaac ctagttcaac tgaggctatt
      421 gcatctgaga agaaagaaga tgaagccgta actccaaaag aggaaaaagt gtctgctaaa
      481 ccggaagaaa aagctccaag gatagaatca caaacttcaa atcaagaaaa accgctcaag
      541 gaagatgcta aagctgtaac aaatgaagaa gtgaatcaaa tgattgaaga caggaaagtg
      601 gattttaatc aaaattggta ttttaaactc aatgcaaatt ctaaggaagc cattaaacct
      661 gatgtagacg tatctacgtg gaaaaaatta gatttaccgt atgactggag tatctttaac
      721 gatttcgatc atgaatctcc tgcacaaaat gaaggtggac agctcaacgg tggggaagct
      781 tggtatcgca agactttcaa actagatgaa aaagacctca agaaaaatgt tcgccttact
      841 tttgatggcg tctacatgga ttctcaagtt tatgtcaatg gtcagttagt ggggcattat
      901 ccaaatggtt ataaccagtt ctcatatgat atcaccaaat accttcacaa agatggtcgt
      961 gagaatgtga ttgctgtcca tgcagtcaac aaacagccaa gtagccgttg gtattcagga
     1021 agtggtatct atcgtgatgt gactttacaa gtgacagata aggtgcatgt tgagaaaaat
     1081 gggacaacta ttttaacacc aaaacttgaa gaacaacaac atggcaaggt tgaaactcat
     1141 gtgaccagca aaatcgtcaa tacggacgac aaagaccatg aacttgtagc cgaatatcaa
     1201 atcgttgaac gaggtggtca tgctgtaaca ggcttagttc gtacagcgag tcgtacctta
     1261 aaagcacatg aatcaacaag cctagatgcg attttagaag ttgaaagacc aaaactctgg
     1321 accgttttaa atgacaaacc tgccttgtac gaattgatta cgcgtgttta ccgtgacggt
     1381 caattggttg atgctaagaa ggatttgttt ggttaccgtt actatcactg gactccaaat
     1441 gaaggtttct ctttgaatgg tgaacgtatt aaattccatg gagtatcctt gcaccacgac
     1501 catggggcgc ttggagcaga agaaaactat aaagcagaat atcgccgtct caaacaaatg
     1561 aaggagatgg gagttaactc catccgtaca acccacaacc ctgctagtga gcaaaccttg
     1621 caaatcgcag cagaactagg tttactcgtt caggaagagg cctttgatac ttggtatggt
     1681 ggcaagaaac cttatgacta tggacgtttc tttgaaaaag atgccactca cccagaagct
     1741 cgaaaaggtg aaaaatggtc tgattttgac ctacgtacca tggtcgaaag aggcaaaaac
     1801 aaccctgcta tcttcatgtg gtcaattggt aatgaaatag gtgaagctaa tggtgatgcc
     1861 cactctttag caactgttaa acgtttggtc aaggttatca aggatgttga taagactcgc
     1921 tatgttacca tgggagcaga taaattccgt ttcggtaatg gtagcggagg gcatgagaaa
     1981 attgctgatg aactcgatgc tgttggattt aactattctg aagataatta caaagccctt
     2041 agagctaagc atccaaaatg gttgatttac ggttcagaaa catcttcagc tacccgtaca
     2101 cgtggaagtt actatcgccc tgaacgtgaa ttgaaacata gcaatggacc tgagcgtaat
     2161 tatgaacagt ctgactatgg aaatgatcgt gtgggttggg ggaaaacagc aaccgcttca
     2221 tggacttttg accgtgacaa cgctggctat gctggacagt ttatctggac aggtacggac
     2281 tatattggtg aacctacacc atggcacaac caaaatcaaa ctcctgttaa gagctcttac
     2341 tttggtatcg tagatacagc cggcattcca aaacatgact tctatctcta ccaaagccaa
     2401 tgggtttctg ttaagaagaa accgatggta caccttcttc ctcactggaa ctgggaaaac
     2461 aaagaattag catccaaagt agctgactca gaaggtaaga ttccagttcg tgcttattcg
     2521 aatgcttcta gtgtagaatt attcttgaat ggaaaatctc ttggttttaa gactttcaat
     2581 aaaaaacaaa ccagcgatgg gcggacttac caagaaggtg caaatgctaa tgaactttat
     2641 cttgaatgga aagttgccta tcaaccgggt accttggaag caattgctcg tgatgaatct
     2701 ggcaaggaaa ttgctcgaga taagattacg actgctggta agccagcggc agttcgtctt
     2761 attaaggaag accatgcgat tgcagcagat ggaaaagact tgacttacat ctactatgaa
     2821 attgttgaca gccaggggaa tgtggttcca actgctaata atctggttcg cttccaattg
     2881 catggccaag gtcaactggt cggtgtagat aacggagaac aagccagccg tgaacgctat
     2941 aaggcgcaag cagatggttc ttggattcgt aaagcattta atggtaaagg tgttgccatt
     3001 gtcaaatcaa ctgaacaagc agggaaattc accctgactg cccactctga tctcttgaaa
     3061 tcgaaccaag tcactgtctt tactggtaaa aaagaaggac aagagaagac tgttttgggg
     3121 acagaagtag caagagttcg tacattaatt ggtaaagaac caaaaatgcc gaaaacagta
     3181 ggttttgtat acagcgatgg tagtcgtgaa aaacttccag taacttggtc tcaagtcgat
     3241 gttagtcaag caggagttgt gactgttaaa ggtacagcaa atggacgtga ggtagaggct
     3301 catgtcgagg ttctagcaat tgcgaaagaa ttaccaacag ttaaacgtat tgctccaaat
     3361 actgacttga attctgtaga caaatctgtt tcttatgttt tgactgatgg aagtgtacaa
     3421 gagtacgaag tagatagctg ggagattacg gaagtagata aagccaaact ttcagtagct
     3481 ggatcacgta ttcaaatgac tggtcagtta gctggagaaa ctattcatgc aacccttgtg
     3541 gtagaagaag gaaatgctgc agcacctgta gtgccaactg ttactgttgg aggtgaggca
     3601 gtaacaggtc ttactagtcg acaaccaatg caatatcgta ctctatctta tggtgcccaa
     3661 ctgccagaag tcacagcaag tgctgaaaat gctgatgtga cagttcttca agcaagcgca
     3721 gcaaacggca tgcgtgcgag catctttatt cagcctaaag atggtggtcc tcttcaaacc
     3781 tatgcaattc aattcctaga agaagcacca aaaattgctc acttgagttt gcaagtggaa
     3841 aaagctgaca gtctcaaaga agaccaaact gtcaaattgt cggttcgagc tcactatcaa
     3901 gatggaacgc aagctgtatt accagctgac aaagtaacct tctctacaag tggtgaaggg
     3961 gaagtcgcaa ttcgtaaagg aatgcttgag ttgcataagc caggagcagt cactctcaaa
     4021 gcggaatatg agggagctaa aggccaagtt gaactcacta tccaagccaa tactgagaag
     4081 aagattgcgc aatctatccg tcctgtaaat gtagtcacag atttgcatca aaaacctact
     4141 cttccaacaa cagtaacggt tgagtatgac aaaggtttcc ctaaagctca caaagtcact
     4201 tggcaagcta ttccgaaaga aaaactagac tcctatcaaa catttgaagt actaggtaaa
     4261 gttgaaggaa ttgaccttga agcgcgtgca aaagtctctg tagaaggtat cgtttcagtt
     4321 gaagaagtca gtgtgacaac tccaatcgca gaagcaccac aattaccaga aagcgttcgg
     4381 acatatgatt caaatggtca cgtttcatca gctaaggttg catgggatgc gattcgtata
     4441 gagcaatacg ctaaggaagg tgtctttaca gttaatggtc gcttagaaga tactcaatta
     4501 acaactaaac ttcatgttcg cgtatctgct caaactgagc aaggtgcaaa catttctgac
     4561 caatggaccg gttcagaatt gccacttgcc tttgcttcag attcaaatcc aagcgaccca
     4621 gtttcaaatg ttaatgacaa gctcatttcc tacaataacc aaccagccaa tcgttggaca
     4681 aactggaatc gtactaatcc agaagcttca gtcggtgttc tgtttggaga ttcaggtatc
     4741 ttgagcaaac gctccgttga taatctaagt gtcggattcc acgaagacca tggagttggt
     4801 gcaccgaagt cttatgtgat tgagtattat gttggtaaga ctgtcccaac agctcctaaa
     4861 aaccctagtt ttgttggtaa tgaggaccat gtctttaatg attctgccaa ctggaaacca
     4921 gttactaatc taaaagcccc tgctcaactc aaggctggag aaatgaacca ctttagcttt
     4981 gataaagttg aaacctatgc tgttcgtatt cgcatggtta aagcagataa caagcgtgga
     5041 acgtctatca cagaggtaca aatctttgcg aaacaagttg cggcagccaa acaaggacaa
     5101 ataagaatcc aagttgacgg caaagactta gcaaacttca accctgattt gacagactac
     5161 taccttgagt ctgtagatgg aaaagttccg gcagtcacag caagtgttag caacaatggt
     5221 ctcgctaccg tcgttccaag cgttcgtgaa ggtgagccag ttcgtgtcat cgcgaaagct
     5281 gaaaatggcg acatcttagg agaataccgt ctgcacttca ctaaggataa gaacttactt
     5341 tctcataaac cagttgctgc ggttaaacaa gctcgcttgc tacaagtagg tcaagcactt
     5401 gaattgccga ctaaggttcc agtttacttc acaggtaaag acggctacga aacaaaagac
     5461 ctgacagttg aatgggaaga agttccagca gaaaatctga caaaagcagg tcaatttacc
     5521 gttcgaggcc atgtccttgg tagtgatctt gttgctgagg tcactgtacg agtgacagac
     5581 aaactaggcg aagctctttc agataaccct aactatgatg aaaacagtaa ccaggccttt
     5641 gcttcagcaa ccaatgatat tgacaaaaac tctcatgacc gcgttgacta tctcaatgac
     5701 ggagatcatt cagaaaatcg tcgttggaca aactggtctc caacaccatc ttctaatcca
     5761 gaagtatcag cgggtgtgat cttccgtgaa aatggtaaga ttgtagaacg gactgttgcc
     5821 caagccaaac ttcgtttctt tgcagatagt ggtacggatg caccaactaa actcgtttta
     5881 gaacgctatg tcggtccaga gtttgaagtg ccaacctact attcaaacta ccaagcctac
     5941 gacgcagacc atccattcaa caatccagaa aattgggaag ctgtgcctta tcgtgcggat
     6001 aaagacatcg cagctggtga tgaaatcaac gtaacattta aagctgtcaa agccaaagct
     6061 atgagatggc gtatggagcg taaagctgac aagagcggtg ttgcgatgat tgagatgacc
     6121 ttccttgcac cgagtgaatt gcctcaagaa agtacgcaat cgaagattct tgtagatgga
     6181 aaagaacttg ctgatttcgc tgaaaatcgt caagactatc aaattaccta taaaggtcaa
     6241 cggccaaaag tctcagttga agaaaacaat caagtagctt caactgtggt agatagtgga
     6301 gaagatagcc ttccagtact tgttcgcctc gtttcagaaa gtggaaaaca agtcaaggaa
     6361 taccgtatcc agttgactaa ggaaaaacca gtttctgctg tacaagaaga tcttccaaaa
     6421 ctcgaatttg ttgaaaaaga tttggcctac aagacagttg agaaaaaaga ttcaacactg
     6481 tatctaggtg aaactcgtgt agaacaagaa ggaaaaactg gtaaagaacg tatctttaca
     6541 gcgattaatc ctgatggaag taaggaagaa aaactccgtg aagtggtaga agctccgaca
     6601 gaccgcatag tcttggttgg aaccaaacca gtagctcaag aagctaaaaa accacaagtg
     6661 tcagaaaaag cagatacaaa accaattgat tcaagtgaag ctagtcaaac taataaagcc
     6721 cagttaccaa atacaggtag tgcggcaagc caagcagcag tagcagcagg tttagctctt
     6781 ctaggtttga gtgcaggatt agtagttact aaaggtaaaa aagaagacta gaaattttga
     6841 taccttcttt atcattaaag accaaagaaa aactcttgtc ctaaatagaa gataaagagt
     6901 ctggaacaaa atagttctca accacaaaaa agctagatat ttccaattgc ggaactctag
     6961 ctttttaatt ttgagtcgtt ctcttattgt atagtagatt gaaactagaa tagtacactt
     7021 ctacttctaa aacattgtta gaaatcaatt tgactgtcct tatcgatttg tcctgttctt
     7081 atttcatttc actatgtttt aggaggttat tggccataag taccaatccc atgtcaattc
     7141 tcacttgacg cttccctctc agattacatc tcttgtaacc caaacaagcc tttatctgcc
     7201 caaagacagg ttccacatca atcttgcgtt gagcgaaaat ctgtctacct tggggagata
     7261 aaagcgcctg acattcttta gctttcaagt tttgatagcg ttcgttcata tacagtccct
     7321 tttgagggac tgattcaggt tcatcagcgt agtaaacctt gatttcctgt tgaaagtctg
     7381 tctgtgtttt ctggtacttg atatggtgaa aacgatagca ccagccatca ggatgtgtgt
     7441 agctatcctc cttgtcatta tagtgccaat tcgctaagtt tttagctgac tgtttatacc
     7501 ctctcttttg ttccttatca aacatggcat atttaatcag aaggggagtg atttcttctt
     7561 gaaaatagac ctgtatctgt tcttgaagtt tggcggagaa tttctctgtc gttttcttcc
     7621 acacaaaact atacttgttg gcattggctt caatcttagt tccgtcaata aacaaacaat
     7681 ctaaggtcac taactcttcc atttttcaat ttttcgacca gagaaaatcc cttgtgaata
     7741 ggcaaataga agagtagata caagcatttt agggtgataa gacgggcgat caaaggcatg
     7801 atagaaggcg tggaagtgac aatcctccaa ggtattcacc actttttcaa tagtaaaaac
     7861 gagatgatct tgtggcaaga aggaactgat ttctagtggt aaagttgttt gatttgtgtt
     7921 atagtgaata tgcatgggat agcctttcta aatggtttat taagcaattc tattttacca
     7981 agactatcgc aaccatgcaa aaaagcaacg gcaaatccgt tgcctttttt ggagataaga
     8041 gactattgtc ccagactctt ttctttgtat aaaattgtat agtgttattg tctatactat
     8101 tttgtagaga aagcaaaaat ccctagaaaa tgcttaggga ttcgactatt tcattaagaa
     8161 caattcaaca atcatttcta tatacatgat aagggttaat aagaatcctg cacgccagaa
     8221 gaatttgata aatttaggat agtaaaagct gcgttttttc aaaaggaaga aaaagacgag
     8281 aataatggct aggatcgaga gggctagccc cagtctaggg aggaaattat gggtaaaggt
     8341 tttagctgta atcaagtaat actcaaatac caagactgga aaagccaaat ccgcaaagtt
     8401 tcgtcctagt ttttttaatc taaaaagttt ggttaggata atgcagacga ctaaggtcag
     8461 tatcaataat aaaatagatg ctaatttcat taaaatcata cccatattgt atcataaaaa
     8521 aaggctaatg gaaacgagaa acagaggaat ttataggaaa gtcaggcttt tgagattgtg
     8581 ggtgattttt gttataatga aagttataaa atcttataat accttgaatg attattatcg
     8641 aaaactcttt ggagaaaaga cttttaaagt ccctattgat gcgggatttg actgtcccaa
     8701 tcgtgatgga actgtggctc atggaggctg tactttttgt acggtttccg gttctggaga
     8761 tgccattgtg gcaccagatg cgcctatccg tgagcaattt tataaggaaa ttgactttat
     8821 tcatcgtaag tggccagatg ttcagaagta tctggtttat tttcaaaatt ttaccaacac
     8881 ccatgaaaag gtggaagtta ttcgagagcg ttatgaacag gctatcaatg agccaggtgt
     8941 ggtaggaatc aatattggaa cgcgcccaga ctgtttacca gacgaaacca tcgaatattt
     9001 ggctgagtta tcggagtgca tgcatgtgac ggttgaattg ggcttgcaaa ctacttatga
     9061 agcaacctct gacctgatta accgtgcgca ttcttatgaa ttgtaggtgg aaacggtcaa
     9121 gcgtttgaga aagtatccaa aaattgagat tgtttcccat ttgatcaatg gtttgcctgg
     9181 tgaaacccat gagatgatgg ttgaaaatgt ccgccgttgt gtcacggata acgatattca
     9241 agggattaaa ctgcatttgc tccatcttat gacaaatact cgtatgcaac gagattacca
     9301 tgaggggcgt ttacaattga tgagtcagga cgaatatgtc agggtcatct gtgaccaact
     9361 ggaaattatt cccaaacata tcgtcatcca tcgaattaca ggagatgcgc ctagggatat
     9421 gctgcttggg cctatgtgga gcctcaataa atgggaagct ctcaacagca ttgagatgga
     9481 gatgcgacgt cgtggaagtg ttcaaggatg caaggctgta aaacaggagt ttgaaaatga
     9541 aaagaccact tgagatggca catgattttt tggctgaggt cgtgacaaaa gaggatgtcg
     9601 tagtggatgc gactatggga aatggtcatg acacgctttt tttagccaag ctagccaagc
     9661 aagtctatgc ctttgatatt cagaagcaag ccttggaaaa gacccaagag cgtttgcatc
     9721 aggctgactt gacaaatgcc cagttaatct tgcaaggcca tgagacactg gaccagtttg
     9781 tgataaaagc taaggcaggg atttttaatc tgggctattt gccgtcagct gataagtctg
     9841 tcatcacccg accgcagaca acgattgagg cattagaaaa gctatgtggc ttacttgtca
     9901 aaggtggacg aattgctatt atgatttact atggtcatga aggaggcgat ctcgagagag
     9961 atgctgtctt ggattttgtg atccagttga accaacaaga gtacacagct gccatttacc
    10021 gaactttaaa ccaagtcaac aacccgccgt ttttagtgat gattgaaaaa ttagagagat
    10081 acagacatgg ataaacaata cctacacgaa aagctggatg ccatgcgcca gaattttgtt
    10141 gaatcaaccc accacgaacg atcggtgggc gtgctagacc aagcgcatat gagcaaaaaa
    10201 atgcttaaaa tcaagaaaaa attagttgct cttgaaatgg aacggtgcca gagaaaaatt
    10261 gagcacaaag actgttccaa gattgaccaa aaaatcaaag agcagaagga gatatttgaa
    10321 tcctgttgta aaaaagatta aggaggacgt gcgtggaatt actgatttac ctcatcctat
    10381 ttttactggt tttgattgtc tcaagtacaa ccaataagct cctgcccttt ttgcctctcc
    10441 ctttggtgca gattcttttg ggaattgtga ttggtctctt tttacccaat actgactttc
    10501 accttaatac ggagttgttt ttggcactgg ttatcggacc cttgcttttc cgagaggctg
    10561 aagaagcaga tgttacggct attttaaaac actggcgaat cattgtttat ctcatatttc
    10621 cagtgatttt tatctcgacc ttgagtttgg gtggcttggc ccatcttctt tggttcagcc
    10681 ttcccttggc agcttgcttg gctgttgggg cagcccttgg tcctacggac ttggtggcct
    10741 ttgcctctct ttcggagcgt tttagctttc ctaagcgcgt gtccaatatt cttaagggcg
    10801 aaggactctt gaatgatgct tctggtttgg tggcttttca ggtagctttg acagcttgga
    10861 caactggagc tttttctctg gggcaagcta gcagttcgct catcttttca atcctaggcg
    10921 gttttttaat tggattttta acggccatga ccaaccgctt cctccatacc ttcttgctaa
    10981 gtgtgcgcgc aacggatatt gccagtgaac ttttattaga attgagtttg cctctagtga
    11041 ccttctttct ggcagaagaa gttcatgttt caggtattat tgccgtcgta gttgctggaa
    11101 ttttaaaggc aagtcgcttc aagaaaatca cgctcctcga agcccaagtg gatacggtga
    11161 ccgagacggt ctggcataca gtgaccttta tgctcaacgg ttctgtcttt gtgattttag
    11221 ggatggagtt ggaaatgata gcagaaccta tcttgaccaa tccaatctat aatcctctac
    11281 ttttattgct atctctcatc gcccttacct ttgtcctctt tgtcattcgt tttattatga
    11341 tctatggcta ttatgcctat agaacccgac gcctcaagaa aaagctaaat aagtatatga
    11401 aggacatgtt tctcttgacc ttttcaggtg ttaagggaac ggtgtcgatt gctacgattc
    11461 tcttgatacc aagtaatcta gaacaggagt atcctctttt gcttttcctt gttgcaggtg
    11521 tgacgcttgt cagcttttta acaggtctct tggtcttgcc tcatctttct gatgaagagg
    11581 aagaaagcaa ggattatctc atgcatatcg ccattttgaa tgaagtaacg ctagagttgg
    11641 aaaaagagtt ggaagacacc agaaataaac ttcccctcta tgcggctatt gacaattatc
    11701 atggacgtat tgaaaatctc attttaagcc aagaaaacca ggatgatcaa gaagattggg
    11761 ctgctttgaa actcttgatt cttagtattg aaagtgatgg tttggaacag gcctatgaag
    11821 aggggaacat tagcaatcgt gcttaccgag tttaccaacg ttatctgaaa aatatagaac
    11881 aaggaatcaa tcgtaaactt gcctcaagac tgacctatta ttttcttgtt tccttgagga
    11941 ttttacgttt tctccttcat gaagttttta ctcttggaaa gaccttccgt agctggaagg
    12001 acaaggagca aagccgtctc cgtgctcttg attatgacca aattgcagag ctctatcttg
    12061 ccaatacaga gatgattatt gaaagtttgg aaaacctgaa gggagtctac agacgctctt
    12121 tgattagttt tatgcaggag tctcgtcttc gagaaacagc tattatcagc agtggtgcct
    12181 ttgtcgaacg ggttatcaat cgtgtcaaac ccaacaatat cgatgaaatg ctgagaggct
    12241 attatctgga gcgcaagttg attttcgaat acgaagaaaa acgattgatt acgactaagt
    12301 atgccaagaa attacgacaa aatgtaaata acttagagaa ctattccttg aaggaagctg
    12361 ccaataccct gccgtatgat atggtggaat tggtaagaag aaattagtta atactcttcg
    12421 aaaatctctt caaaccacgt cagcgtcgcc ttggattata tatgtgactg acttcgtcag
    12481 tttcatctac aacctcaaag cagggctttg agcaacctgc ggctagcttc ctagtttgct
    12541 ctttgatttt cattgagtat aagattataa atgaaggagt atgacatgaa aaagtggtgg
    12601 aaagagctga tagacaagcc tttattaaaa gcttttttgc attattatca agcatcagat
    12661 agtgagttga ccagtgtcgc agtagcctac tattggttga tttcgatttt ccccctgctt
    12721 ttggtggtgg tcaatatcct cccctatttt cagattcctg tgggagaatt tctgtgcttt
    12781 atgaaagacg ttctgccccc aagcctctat gaaggtgtgg aaaaaatagc cagagaagtt
    12841 ttgacgcaac cttcaacagg tttattgagt ttttctgttt tatcggcgtt atggagtttt
    12901 tcaaaatcta tgaatttctt gcaaaaagct tttaacaagg cttatggcgt cgaaaagagt
    12961 cgtggactta tttcccatca gatgctaagt ctcctagtca gttttggctt gcagctcctc
    13021 tttgcgtttg ccttgttttt gatcttattt ggtcagatga ttttggcttt acttgctcat
    13081 tattggacaa aagatggcat tatctatcag gctttacaag ggttggcagg tcctctgatt
    13141 tacgccctcc tctttgctat cttggtcatg ctttattatt ttcttcccaa tctatctaac
    13201 aggaaaatta gctataccct accaggcagt gcctttgttc tcttagtgat tttaggttta
    13261 ctaactctgt tctctagtta tctcaattac tatgtccatc atttggtgga tgtccgaatt
    13321 ttaggttccg ttcttcttgt tgttatgatg ttttggttta tcttgattgc taaaattgtt
    13381 atcctaggcg cggttatcaa tgccagtatg cagagtttga aagatccggt ctttaaaaaa
    13441 gactaactat ttatccatta caaaagcgca tagtatcaaa actttataga accttgatac
    13501 tatgcgcttt tgtgctttga cagttttttg tatagttttt gtccaagatt tctaaatcat
    13561 ctgattaaat tcctattttc ccctatcatt gtccctgttt tttcgaaaat ggaaggagta
    13621 taataaatct atcaataaaa tgataggagg aactttatgg gtcatatttt cttttttcta
    13681 agtgtctttt tggcagggat tctatccttc ttttctcctt gtatcttacc tttgttaccg
    13741 gtctatacag gagtgttact agatgataag gatggtgctc aggcttctag cggcaaattt
    13801 tcaatctcag ttactagttt attacgaact ctggccttta tagcaggaat ttcctttata
    13861 tttattttgt tgggctatgg agctggtttt ttaggcgatt tgctttatgc ttcttggttc
    13921 caatatctta ctggggcaat tattatcctt cttggtttgc accaaatgga gattctacac
    13981 tttaaggggc tttataagga aaagaggcta caactgcaag gacaggggca aaatggtaag
    14041 ggctatagtc aggcattttt attgggcttg acctttagtt ttgcttggac gccttgcgtg
    14101 gggccggttc tggggtctgt tttggccttg gcggcttcag gtggttcagg agcttggcag
    14161 ggagctggtc tcatgttggt gtatacgctg ggcttggcgc taccattctt gcttctagct
    14221 ctgacctcta gttatgtttt gaaacatttc cgaaaacttc atccctatct cggaatcctc
    14281 aaaaaagtgg gtggttttct cattattgtg atgggactct tggttctgtt tggaaatgct
    14341 tcaattttaa gtcaattatt tgaataaaat ggaaaggaat atcaatatga aaaaatggca
    14401 aacatgtgtt cttggagcag gttcgctcct ttgtttgacg gcttgttcag gcaagtccgt
    14461 gactagtgaa caccaaacga aagatgaaat gaagacggag cagacagcta gtaaaacaag
    14521 cgcagctaaa gggaaagagg tggctgattt tgaattgatg ggagtagatg gcaagaccta
    14581 ccgtttatct gattacaagg gcaagaaagt ctatctcaaa ttctgggctt cttggtgttc
    14641 catctgtctg gctagtcttc cagatacgga tgagattgct aaagaagctg gtgatgacta
    14701 tgtggtcttg acagtagtgt caccaggaca taagggagag caatctgaag cggactttaa
    14761 gaattggtat aagggattgg attataaaaa tctcccagtc ctagttgacc catcaggcaa
    14821 acttttggaa acttatggtg tccgttctta cccaacccaa gcctttatag acaaagaagg
    14881 caagctggtc aaaacacatc caggattcat ggaaaaagat gcaattttgc aaactttgaa
    14941 ggaattagcc taggaggtgt cttatgaatg ataagttaaa aatcttcttg ttgctaggag
    15001 tattttttct agccataacc ggtttctatg ttctattgat acgaaatgca gggcagacag
    15061 atgcctcgca aattgaaaag gcggcagtta gccaaggagg aaaagcagtg aaaaaaacag
    15121 aaattagtaa agacgcagac ttgcacgaaa tttatctagc tggaggttgt ttctggggag
    15181 tggaggaata tttctcacgc gttcccgggg tgacggatgc cgtttcaggc tatgcaaatg
    15241 gtagaggaga aacaaccaag tacgaattga ttaaccaaac aggtcatgca gaaaccgtcc
    15301 atgtcaccta tgatgccaag caaatttctc tcaaggaaat cctgcttcac tatttccgca
    15361 ttatcaatcc aaccagcaaa aataaacaag gaaatgatgt ggggacccag taccgtactg
    15421 gtgtttatta cacagatgac aaggatttgg aagtgattaa ccaagtcttt gatgaggtgg
    15481 ctaagaaata cgatcaacct ctagcagttg aaaaggaaaa cttgaagaat tttgtggtgg
    15541 ctgaggatta ccatcaagac tatctcaaga aaaatccaaa tggctactgc catatcaatg
    15601 ttaatcaggc ggcctatcct gtcattgatg ccagcaaata tccaaaacca agtgatgagg
    15661 aattgaaaaa gaccctgtca cctgaggagt atgcagttac ccaggaaaat caaacagaac
    15721 gagctttctc aaaccgttac tgggataaat ttgaatccgg tatctatgtg gatatagcaa
    15781 ctggggaacc tctcttttca tcaaaagaca aatttgagtc tggttgtggc tggcctagtt
    15841 ttacccaacc catcagtcca gatgttgtca cctacaagga agataagtcc tacaatatga
    15901 cgcgtatgga agtgcggagc cgagtaggag attctcacct tgggcatgtc tttacggatg
    15961 gtccacagga caagggcggc ttacgttact gtatcaatag cctctctatc cgctttattc
    16021 ccaaagacca aatggaagaa aaaggctacg cttatttact agattatgtt gattaatact
    16081 cttcgaaaat ctcttcaaac cacgtcagcg tcgccttacc gtatgtaggg tt
//
LOCUS       DAVBBO010000049        16074 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ST1
            SAMEA2066453-rid20184263.denovo.049, whole genome shotgun sequence.
ACCESSION   DAVBBO010000049 DAVBBO010000000
VERSION     DAVBBO010000049.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2066453
            Sequence Read Archive: ERR351777
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 16074)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 16074)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980402.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980402.1
            Genome Coverage       :: 176x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:17:33
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,141
            CDSs (total)                      :: 2,104
            Genes (coding)                    :: 1,953
            CDSs (with protein)               :: 1,953
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 16S)
            partial rRNAs                     :: 1 (23S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 151
            CDSs (without protein)            :: 151
            Pseudo Genes (ambiguous residues) :: 0 of 151
            Pseudo Genes (frameshifted)       :: 73 of 151
            Pseudo Genes (incomplete)         :: 76 of 151
            Pseudo Genes (internal stop)      :: 40 of 151
            Pseudo Genes (multiple problems)  :: 32 of 151
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..16074
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2066453-rid20184263.denovo.049"
                     /strain="ST1"
                     /db_xref="taxon:1313"
     gene            66..530
                     /locus_tag="VQU30_001631"
     CDS             66..530
                     /locus_tag="VQU30_001631"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001146193.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldose epimerase"
                     /protein_id="HET2447704.1"
                     /translation="MGGHPGFNCLLLDDEVYEDYYLEFEKEEICSVPRPFPETGMLDF
                     QDRSPWLEGQKEIDLSYDLFSTDAVTLDELQSRTIALRSLKHDKGLKVHFAEFPNLII
                     WSTLNKGPFITFEPWSGLSTFLEEGDHLEDKKNVCLLEANQVEELGFEIEVL"
     gene            688..1113
                     /gene="lacA"
                     /locus_tag="VQU30_001632"
     CDS             688..1113
                     /gene="lacA"
                     /locus_tag="VQU30_001632"
                     /EC_number="5.3.1.26"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398701.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactose-6-phosphate isomerase subunit LacA"
                     /protein_id="HET2447705.1"
                     /translation="MSIVIGADAAGLRLKEVVKDFLEKENFHLVDVTAEGQDFVDVTL
                     AVAAEVNKEEQNLGIVIDAYGAGPFMVATKIKGMVAAEVSDERSAYMTRGHNNSRMIT
                     MGAQLVGDELAKNIAKGFVNGKYDGGRHQIRVDMLNKMG"
     gene            1144..1659
                     /gene="lacB"
                     /locus_tag="VQU30_001633"
     CDS             1144..1659
                     /gene="lacB"
                     /locus_tag="VQU30_001633"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002994294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactose-6-phosphate isomerase subunit LacB"
                     /protein_id="HET2447706.1"
                     /translation="MRIAIGCDHIVTDEKMAVSEFLKSKGYEVIDFGTYDHTRTHYPI
                     FGKKVGEAVTSGQADLGVCICGTGVGINNAVNKVPGVRSALVRDMTTALYAKEQLNAN
                     VIGFGGKITGELLMCDIIEAFIHAEYKPSEENKKLIAKIEHLESHNAQQTDANFFTEF
                     LEKWDRGEYHD"
     gene            1670..2599
                     /locus_tag="VQU30_001634"
     CDS             1670..2599
                     /locus_tag="VQU30_001634"
                     /EC_number="2.7.1.144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000604270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tagatose-6-phosphate kinase"
                     /protein_id="HET2447707.1"
                     /translation="MILTVTMNPSIDISYPLDELKIDTVNRVVDVTKTAGGKGLNVTR
                     VLSEFGDSVLATGLVGGKLGEFLVEHIDDQVKKDFFSIQGETRNCIAILHGDNQTEVL
                     EKGPEVLEQEGQDFLEHFKKLLESVEVVAISGSLPAGLPVDYYASLVELANQAGKLVV
                     LDCSGAALQAVLESPHKPTVIKPNNEELSQLLGREVSEDLEELKEVLQESLFTGIEWI
                     IVSLGANGTFAKHGDTFYKVDIPRIQVVNPVGSGDSTVAGISSGLLHKESDAGLLIKA
                     NVLGMLNAQEKMTGHVNMANYQALYDQLIVKEV"
     gene            2601..3581
                     /gene="lacD"
                     /locus_tag="VQU30_001635"
     CDS             2601..3581
                     /gene="lacD"
                     /locus_tag="VQU30_001635"
                     /EC_number="4.1.2.40"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001229146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tagatose-bisphosphate aldolase"
                     /protein_id="HET2447708.1"
                     /translation="MALTEQKRVRLEKLSDENGIISALAFDQRGALKRLMAQHQTEEP
                     TVAQMEELKILVADELTKYASSMLLDPEYGLPATKALDEKAGLLLAYEKTGYDTTSTK
                     RLPDCLDVWSAKRIKEEGADAVKFLLYYDVDSSDELNQEKQAYIERIGSECVAEDIPF
                     FLEILAYDEKIADAGSVEYAKVKPHKVIGAMKVFSDPRFNIDVLKVEVPVNIKYVEGF
                     AEGEVVYTREEAAAFFKAQDEATNLPYIYLSAGVSAKLFQDTLVFAHESGANFNGVLC
                     GRATWAGSVEAYIKDGEAAAREWLRTTGFENIDELNKVLQTTATSWKERV"
     gene            3815..4651
                     /locus_tag="VQU30_001636"
     CDS             3815..4651
                     /locus_tag="VQU30_001636"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000285719.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antiterminator"
                     /protein_id="HET2447709.1"
                     /translation="MYRILNPMNHNVSLVRNDKGEEVIVIGKGIAFGKKKGDLIAENH
                     VEKIFRMKTEESRENFMALLKDVPLDFITVTYEIIDKLSKKYHYPIQEYLYVTLTDHI
                     YCSYQALIQGRYKDSNLPDISAKYPVAFQIANEAFEIYRQKLADHFPEDEIIRIAYHF
                     INAEGENEVELVESIDKRKEILRNVEEVLTDYAIQRTKKNNHFYDRFMIHLNYFLDYL
                     DRSRDDNQSLLDMEDHIKQSYPKAFEIGSKIYDVITQHTGLDLYKSERVYLVLHIQRL
                     LS"
     gene            4687..5004
                     /locus_tag="VQU30_001637"
     CDS             4687..5004
                     /locus_tag="VQU30_001637"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HET2447710.1"
                     /translation="MNREEVTLLGFEIVAYAGDARSKLLEALKAAEAGDFEKADALVE
                     EAGSCIAEAHHAQTSLLTKEASGEDLAYSVTMMHGQDHLMTTILLKDLMHHLIELYKR
                     GVK"
     gene            5006..6700
                     /locus_tag="VQU30_001638"
     CDS             5006..6700
                     /locus_tag="VQU30_001638"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001037357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HET2447711.1"
                     /translation="MDKLIIFIEKGKPFFEKLSRNIYLRAIKDGFISSMPAVLFSSIF
                     ILIAAVPNIFGFKWSDEQLAFILKPYNYSMGILALLVAGTTAKSLTDSVNTRSMEKTN
                     QINYMSTFLAAVVGLLILAADPIEGGFANGLLGTRGLLTAFLAAFITVNIYKVCIKNN
                     VTIRLPEEVPPNIAQVFKDVIPFALSVLSIYGLDLIVRNIFGTNVAESVGKILAPLFS
                     ATDGYIGLAIVFGAYAFFWFVGIHGPSVVEPLIVAISYANIEANVQLVQAGMHADKIL
                     NPVTQTFVVTMGGTGATLVVPFMFMWLCKSKRNRIVGRASVVPTFFGVNEPILFGAPI
                     VLNPIFFIPFVTAPIINVWIMKFFVDVLQMNSFSIILPWTTPAPIGIVMGTALAPLSF
                     VLAITLIIIDTLIYYPFVKVYDHQILEEERSGKSNDELKEKVAANFNTAKADAILEKA
                     GVDAAQNTITEETNVLVLCAGGGTSGLLANALNKAAAEYNVPVKAAAGGYGAHREMLP
                     EFDLVILAPQVASNFEDMKAETDKLGIKLAKTEGAQYIKLTRDGKGALAFVQAQFD"
     gene            6909..8315
                     /gene="lacG"
                     /locus_tag="VQU30_001639"
     CDS             6909..8315
                     /gene="lacG"
                     /locus_tag="VQU30_001639"
                     /EC_number="3.2.1.85"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864138.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-galactosidase"
                     /protein_id="HET2447712.1"
                     /translation="MTKTLPKDFIFGGATAAYQAEGATHTDGKGPVAWDKYLEDNYWY
                     TAEPASDFYNRYPVDLKLAEEYGVNGIRISIAWSRIFPTGYGQVNAKGVEFYHNLFAE
                     CHKRHVEPFVTLHHFDTPEALHSNGDFLNRENIEHFVDYAAFCFEEFPEVNYWTTFNE
                     IGPIGDGQYLVGKFPPGIQYDLAKVFQSHHNMMVSHARAVKLYKDKGYKGEIGVVHAL
                     PTKYPLDPKNPSDVRAAELEDIIHNKFILDATYLGRYSAETMEGVNHILSVNGGSLDL
                     REEDFTALEAAKDLNDFLGINYYMSDWMEAFDGETEIIHNGKGEKGSSKYQIKGVGRR
                     VAPDYVPRTDWDWIIYPQGLYDQIMRVKKDYPNYKKIYITENGLGYKDEFVDNTVYDD
                     GRIDYVKQHLEVLSDAIADGANVKGYFIWSLMDVFSWSNGYEKRYGLFYVDFETQERY
                     PKKSAHWYKKVAETQIID"
     gene            8358..8540
                     /locus_tag="VQU30_001640"
     CDS             8358..8540
                     /locus_tag="VQU30_001640"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000471575.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3884 family protein"
                     /protein_id="HET2447713.1"
                     /translation="MFKDFIQSIYEKVYIINFEKCSQIPCLTSEELKSLFLNFINPEE
                     WDTISFDSDFMPFQQS"
     gene            complement(8818..9579)
                     /locus_tag="VQU30_001641"
     CDS             complement(8818..9579)
                     /locus_tag="VQU30_001641"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000917571.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HET2447714.1"
                     /translation="MLKQEKLAKILEIVNSKGTITVKQIMDEIAVSDMTARRYLQELA
                     DKDLLIRVHGGAEKLRTNSLLTNERSNIEKQALQTAEKQEIAHFAGSLVEERETIFIG
                     PGTTLEFFARELPIDNIRVVTNSLPVFLILSERKLTDLILIGGNYRDITGAFVGTLTL
                     QNLSNLQFSKAFVSCNGIQNGALATFSEEEGEAQRIALNNSNKKYLLADHSKFNKFDF
                     YTFYNVSNLDTIVSDSKLSDSILFKLSKHIKVIKP"
     gene            complement(9761..10723)
                     /gene="nrdF"
                     /locus_tag="VQU30_001642"
     CDS             complement(9761..10723)
                     /gene="nrdF"
                     /locus_tag="VQU30_001642"
                     /EC_number="1.17.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004253599.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class 1b ribonucleoside-diphosphate reductase
                     subunit beta"
                     /protein_id="HET2447715.1"
                     /translation="METYYKAINWNAIEDVIDKSTWEKLTEQFWLDTRIPLSNDLDDW
                     RKLSNKEKDLVGKVFGGLTLLDTMQSETGVQALRADIRTPHEEAVFNNIQFMESVHAK
                     SYSSIFSTLNTKAEIEEIFEWTNTNPYLQKKAEIVNEIYLNGSPLEKKVASVFLETFL
                     FYSGFFTPLYYLGNNKLANVAEIIKLIIRDESVHGTYIGYKFQLGFNELPEEEQEKLK
                     EWMYDLLYTLYENEEGYTESLYDGVGWTEEVKTFLRYNANKALMNMGQDPLFPDSAED
                     VNPIVMNGISTGTSNHDFFSQVGNGYLLGEVEAMQDDDYNYGLD"
     gene            complement(10911..13070)
                     /gene="nrdE"
                     /locus_tag="VQU30_001643"
     CDS             complement(10911..13070)
                     /gene="nrdE"
                     /locus_tag="VQU30_001643"
                     /EC_number="1.17.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000523276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class 1b ribonucleoside-diphosphate reductase
                     subunit alpha"
                     /protein_id="HET2447716.1"
                     /translation="MGLKHLEDVTYFRLNNEINRPVNGQIMLHKDKEALDAFFKENVV
                     PNTMVFDSIKDKINYLIEHNYIETAFIKKYRPEFLEELAQFIKDQNFQFKSFMAAYKF
                     YNQYALKTNDGEYYLENMEDRVFFNALYFADGNEAVAIDIANEIIHQRYQPATPSFLN
                     AGRARRGELVSCFLIQVTDDMNSIGRSINSALQLSRIGGGVGITLSNLREAGAPIKGY
                     EGAASGVVPVMKLFEDSFSYSNQLGQRQGAGVVYLNVFHPDIIAFLSTKKENADEKVR
                     VKTLSLGVVVPDKFYELARKNEEMYLFSPYSVEKEYGVPFNYIDITEKYDELVANPNI
                     RKTKIKARDLETEISKLQQESGYPYVVNIDTANRANPVDGKIIMSNLCSEILQVQEPS
                     LINDAQEFLQMGTDVSCNLGSTNVVNMMTSPDFGRSIRAMVRALTFVTDSSHIVAVPT
                     IDHGNSQAHTFGLGAMGLHSYLAQQLIEYGSPESVEFTSIYFMLMNYWTLVESNNIAR
                     ERGITFHNFEKSDYANGSYFDKYVTGEFVPTSDRVKELFKNVFIPGVADWAELRDKVQ
                     EDGLYHQNRLAVAPNGSISYINDVSASIHPITQRIEERQEKKIGKIYYPAAGLSTETI
                     PYYTSAYDMDMRKVIDVYAAATEHVDQGLSLTLFMRSDIPKGLYEWKRENKQTTRDLS
                     ILRNYAFNKGIKSIYYVRTFTDDGGEVGANQCESCVI"
     gene            complement(13151..13369)
                     /gene="nrdH"
                     /locus_tag="VQU30_001644"
     CDS             complement(13151..13369)
                     /gene="nrdH"
                     /locus_tag="VQU30_001644"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000259243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutaredoxin-like protein NrdH"
                     /protein_id="HET2447717.1"
                     /translation="MVTVYSKNNCVQCKMTKRFLDSNNVSYREINLDEQPEYVDQVKE
                     LGFSAAPVIQTPTEVFSGFQPGKLKQLA"
     gene            13720..13983
                     /locus_tag="VQU30_001645"
     CDS             13720..13983
                     /locus_tag="VQU30_001645"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019775469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphocarrier protein HPr"
                     /protein_id="HET2447718.1"
                     /translation="MASKDFHVVAETGIHARPATLLVQTASKFASDITLEYKGKSVNL
                     KSIMGVMSLGVGQGADVTISAEGADADDAIAAISETMEKEGLA"
     gene            13989..15722
                     /gene="ptsP"
                     /locus_tag="VQU30_001646"
     CDS             13989..15722
                     /gene="ptsP"
                     /locus_tag="VQU30_001646"
                     /EC_number="2.7.3.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397822.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoenolpyruvate--protein phosphotransferase"
                     /protein_id="HET2447719.1"
                     /translation="MTEMLKGIAASDGVAVAKAYLLVQPDLSFETITVEDTNAEEARL
                     DAALQASQDELSVIREKAVGTLGEEAAQVFDAHLMVLADPEMISQIKETIRAKKVNAE
                     AGLKEVTDMFITIFEGMEDNPYMQERAADIRDVTKRVLANLLGKKLPNPASINEEVIV
                     IAHDLTPSDTAQLDKNFVKAFVTNIGGRTSHSAIMARTLEIAAVLGTNNITEIVKDGD
                     ILAVNGITGEVIINPTDEQAAEFKAAGEAYAKQKAEWALLKDAQTVTADGKHFELAAN
                     IGTPKDVEGVNNNGAEAVGLYRTEFLYMDSQDFPTEDEQYEAYKAVLEGMNGKPVVVR
                     TMDIGGDKELPYFDMPHEMNPFLGFRALRISISETGDAMFRTQIRALLRASVHGQLRI
                     MFPMVALLKEFRAAKAVFDEEKANLLAEGVAVADNIQVGIMIEIPAAAMLADQFAKEV
                     DFFSIGTNDLIQYTMAADRMNEQVSYLYQPYNPSILRLINNVIKAAHAEGKWAGMCGE
                     MAGDQQAVPLLVGMGLDEFSMSATSVLRTRSLMKKLDTAKMEEYANRALTECSTMEEV
                     LELQKEYVNFD"
     gene            15977..>16074
                     /locus_tag="VQU30_001647"
     CDS             15977..>16074
                     /locus_tag="VQU30_001647"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001835054.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pneumococcal-type histidine triad protein"
                     /protein_id="HET2447720.1"
                     /translation="MKINKKYLVGSAAALILSVCSYELGLYQARTV"
BASE COUNT         5027 a         2818 c         3331 g         4898 t
ORIGIN      
        1 ataaactaga attctagttt tgcaggaagt ctaataaaga aactagcaag gtcaggcctt
       61 actttattgg tggacatcca ggatttaatt gtcttctact tgatgatgaa gtctatgaag
      121 attattatct agagtttgag aaagaagaga tttgctctgt tccacgtcct ttcccagaaa
      181 caggtatgtt ggatttccaa gatagaagtc catggctaga gggacaaaaa gaaatagatc
      241 ttagttatga tcttttcagc acagatgcag tgactttgga tgaattgcaa tctcgaacaa
      301 ttgcccttcg ttctcttaaa catgataagg gattgaaagt gcattttgca gaatttccaa
      361 acctcatcat ctggtcaact ttgaacaagg gacctttcat tacctttgaa ccatggtctg
      421 gcttgtcaac attccttgaa gaaggagatc atttagaaga taagaagaat gtttgtctct
      481 tagaagccaa tcaggttgaa gaattagggt ttgagataga agttttataa aaaaagtaaa
      541 aaataaataa caaaaacaaa cacaaactgt tgacttcttc aaacaatagt agtatattat
      601 gtttgtgagg actaattgac tgttttttaa agacagccaa tacactgctg gaatccagca
      661 tagaaaaaat aaaaaggagt atacaatatg tctattgtta tcggtgcaga tgctgcaggt
      721 ttgagattga aagaagttgt gaaagacttc ttagaaaaag aaaacttcca ccttgtggat
      781 gttacagctg aaggtcaaga ctttgttgat gtgactctcg ctgttgctgc agaagtaaac
      841 aaagaagaac aaaaccttgg tatcgtgatt gatgcttatg gagctggtcc atttatggtt
      901 gcaactaaga tcaaaggaat ggttgctgca gaagtatctg acgaacgttc agcttatatg
      961 actcgtggcc acaacaactc acgtatgatc actatggggg cacaacttgt tggtgatgaa
     1021 ttggctaaaa acatcgctaa aggatttgtt aatggtaaat acgacggtgg acgtcatcaa
     1081 atccgggttg acatgttgaa caaaatgggc taattagatt acagtaagaa aggtaagtta
     1141 aaaatgagaa ttgcaattgg atgcgaccac atcgtaacag atgaaaaaat ggcggtttca
     1201 gaatttttga aatcaaaagg atatgaagtc attgactttg gtacatatga ccatacacgg
     1261 actcactacc caatctttgg taaaaaagta ggggaagctg taactagcgg ccaagctgat
     1321 cttggggtat gtatctgtgg tactggtgtt ggtatcaaca acgctgtaaa taaagttcca
     1381 ggtgttcgtt ctgccttggt tcgtgatatg acaacagccc tttatgctaa agaacaattg
     1441 aacgctaacg ttatcggctt tggtggtaag attactggtg aattgcttat gtgtgatatc
     1501 atcgaagctt tcattcatgc tgaatacaaa ccatctgaag aaaacaagaa attgattgcg
     1561 aaaattgaac accttgaaag tcacaatgct caacaaacag acgcaaactt ctttacagaa
     1621 ttccttgaaa aatgggatcg cggagaatac cacgactaag aggtgaccta tgattttaac
     1681 agtcacaatg aacccatcca ttgatatttc ctatcccttg gatgagttga agattgatac
     1741 tgtcaatcgt gtggtggatg taaccaaaac ggctggtggt aagggactta atgttacccg
     1801 agtactttca gaatttggtg attctgttct tgctactggt ttagtgggtg gcaaacttgg
     1861 tgagtttttg gttgaacata tcgatgatca agtaaagaaa gatttctttt ctattcaggg
     1921 agaaactcgt aactgtatcg ctattctcca cggtgacaac caaacagaag ttcttgaaaa
     1981 aggtcctgaa gtattggaac aggaaggtca agactttttg gaacatttca aaaaactctt
     2041 ggagtcagtt gaagtagtag ccatctcagg tagtctgcca gctggccttc cagttgatta
     2101 ctatgcgagc ttggtagagc ttgctaatca agctggcaag ctagtagtct tggactgctc
     2161 tggtgcagca cttcaggcgg ttcttgaatc accccataaa ccgacagtaa tcaaacccaa
     2221 taatgaggaa ttgtctcagc ttctaggaag agaagtttct gaggatttgg aggaattaaa
     2281 agaagtcctt caagaatctt tgtttacagg gattgaatgg attatcgttt cacttggtgc
     2341 caacggtact tttgccaaac atggtgacac tttctacaag gtagatattc ctagaattca
     2401 ggtggtaaat cctgttggat ctggagactc tactgtggca ggaatttctt caggacttct
     2461 tcacaaagaa tcggatgcag gattactcat caaggcaaat gtccttggta tgctcaatgc
     2521 tcaagaaaaa atgactggtc atgtcaacat ggccaactat caagctctat atgatcaatt
     2581 aatagtaaaa gaggtataaa atggctttaa cagaacaaaa acgtgtacgc ttagaaaaac
     2641 tttctgatga aaatggtatc atctcagctc ttgcatttga ccaacgtggt gctttgaaac
     2701 gcctcatggc tcaacaccaa acagaagaac caactgtggc ccaaatggaa gaacttaaaa
     2761 tcttggtagc agatgaattg actaaatacg cttcatctat gcttcttgac cctgagtatg
     2821 gacttccagc aactaaggct cttgatgaaa aagctggtct tctccttgct tatgaaaaaa
     2881 caggttatga cacaacaagc acaaaacgct tgccagactg cttggatgtt tggtctgcaa
     2941 aacgtattaa agaagaaggt gcagatgcag ttaaattctt gctttactat gatgtagata
     3001 gctcagacga actcaatcaa gaaaaacaag cctacatcga acgcatcggt tctgagtgtg
     3061 tggctgaaga tatcccattc ttccttgaaa tccttgctta cgatgaaaaa attgcggacg
     3121 caggttctgt agaatacgct aaagtaaaac cacacaaagt tatcggtgct atgaaagtct
     3181 tttcagaccc acgttttaac attgatgtct tgaaagttga agttcctgtt aacattaaat
     3241 atgttgaagg cttcgctgag ggtgaagtgg tttacacacg tgaagaagca gcagccttct
     3301 tcaaagcgca agatgaagca acgaacttgc catacatcta cttgagtgct ggtgtatcag
     3361 ctaaactctt ccaagatact cttgtatttg ctcatgaatc aggtgcaaac tttaacggag
     3421 ttctttgtgg tcgtgctaca tgggcagggt cagttgaagc ttacatcaaa gatggtgaag
     3481 cagcagctcg cgaatggctt cgcacaactg gatttgaaaa cattgatgag ctcaataaag
     3541 ttcttcaaac aacagcgact tcatggaaag aacgtgtgta agaaagtcct cctagtttag
     3601 gaacatgaat ctaaaaaaat ttaaaaaaag ttgtatgtaa aggtttacaa aataacttac
     3661 ttgtgctata cttaaatcac aagttaatac aaggtgagtg ttactaagta atattaggca
     3721 tgatcacagg tgaattagaa atcagctgat tttctagttc atttgtggtc attttttgta
     3781 ctcatatacc tttaagatat aaaaggaggt tgacatgtat cgaattctaa atccaatgaa
     3841 tcacaatgtc tcgcttgtca gaaatgataa gggagaagag gtgattgtaa ttggtaaggg
     3901 gattgcattc ggaaagaaga agggggattt gattgctgaa aatcatgttg agaaaatctt
     3961 tcggatgaag accgaagagt ccagagaaaa ctttatggct cttctcaaag atgttccgct
     4021 tgattttatc acagtgacct atgaaatcat tgataagcta tcaaagaaat atcattatcc
     4081 gattcaagag tatctctatg taaccttgac agatcatatt tactgttctt atcaagctct
     4141 aattcaagga aggtacaagg atagtaatct gccagatatt tctgctaagt atcctgtcgc
     4201 ttttcaaatc gcaaatgaag cttttgaaat ttaccgtcag aagctagcag atcattttcc
     4261 tgaggacgaa attattcgga ttgcttatca tttcattaat gctgaaggtg aaaatgaagt
     4321 ggaacttgtg gagtcgattg ataagaggaa agaaattctc aggaatgttg aagaagtttt
     4381 aacggactat gcaattcaac gaactaaaaa gaataaccat ttctatgatc gctttatgat
     4441 ccatttgaat tatttcttgg attatttaga cagatctaga gatgataacc aatcacttct
     4501 ggatatggaa gatcatatta aacaatccta tccaaaagcc ttcgagattg gttccaagat
     4561 ctatgatgtg attacgcaac atacgggtct tgatttgtat aaaagtgaac gagtttatct
     4621 agttctacat atccaacgtt tattgtcata aaaatttatt taaaactata taaggagaat
     4681 tctatcatga atagagaaga agtaacattg ttaggttttg aaatcgtagc ctatgctggc
     4741 gatgctcgtt caaaactatt ggaagccttg aaggctgctg aagctggtga ttttgaaaaa
     4801 gcggacgctc tggtagagga agctggtagc tgtattgcag aggctcacca cgcgcaaaca
     4861 agtctattga ctaaggaagc ttctggtgag gacttagcgt atagtgtgac catgatgcat
     4921 ggtcaagatc acttgatgac aactatcttg ttaaaagacc taatgcacca tttaattgaa
     4981 ctttacaaga gaggagttaa ataaaatgga taagttaata atttttattg agaaaggaaa
     5041 gcctttcttt gagaaattat cgagaaatat atacttaaga gcgataaaag atggttttat
     5101 ttccagtatg ccagcagtat tattctcaag tatttttata ctaatagctg ctgtgcccaa
     5161 tatttttggg tttaaatggt ctgatgaaca gttagctttt attttgaaac cttacaacta
     5221 ctcaatgggg attttagctc tcttagtagc tgggacaact gcaaaatcgt taacagattc
     5281 agttaataca cgtagtatgg agaaaaccaa ccaaatcaac tacatgtcaa cttttttagc
     5341 agctgttgtt ggattgttaa tactggcagc tgatccaatt gaaggtggat ttgctaatgg
     5401 tcttttaggt actagaggat tacttactgc atttttggca gcttttatta cagtaaatat
     5461 ctataaagta tgtattaaaa ataatgtaac cattagactt cctgaagagg ttccaccaaa
     5521 tattgcacaa gtttttaaag atgttattcc gtttgcctta tctgttcttt caatatatgg
     5581 attggattta attgttagaa atatttttgg tacaaatgta gcagaatctg ttggtaaaat
     5641 attagcccct ctattttcag ctactgatgg ttatatcggt ttagctattg tatttggtgc
     5701 ttatgctttc ttttggtttg ttggaattca tgggccatct gttgtagaac ctttaattgt
     5761 agctatcagt tatgcaaata tagaagctaa tgttcagctt gtgcaagctg gtatgcacgc
     5821 agataaaatt ttaaatccag ttactcaaac ttttgttgta acaatgggtg gtactggtgc
     5881 aacactagta gttccattta tgtttatgtg gttatgtaaa tcaaaaagaa atagaattgt
     5941 cggacgtgcg tctgtagttc ctactttctt tggcgtaaat gaaccaatcc tatttggtgc
     6001 tccaattgtt ttaaatccta tcttctttat tccgtttgtt actgctccta ttatcaatgt
     6061 ttggattatg aaattttttg tagatgttct acaaatgaat agtttcagta ttattttacc
     6121 ttggacaaca cctgctccaa ttggtattgt tatgggaacg gcgctggctc cattgtcatt
     6181 cgtcttggct ataactttaa tcattatcga cactttaatc tattatccat ttgttaaagt
     6241 ttatgaccat caaattttag aagaagaacg ttcaggtaag tctaatgatg aattgaaaga
     6301 aaaagttgct gcaaacttca acactgcaaa agcggatgct attcttgaaa aagcgggtgt
     6361 cgatgcagca caaaatacca tcactgaaga aacaaatgtc ctcgttctct gtgcaggtgg
     6421 aggaacaagt ggtctccttg caaatgcttt gaataaggca gcagcagaat acaatgtccc
     6481 tgtgaaagca gcagcaggcg gctatggtgc tcaccgtgaa atgttaccag agtttgatct
     6541 tgttatcctt gcccctcaag ttgcttcaaa ctttgaagat atgaaagcag aaacagataa
     6601 gctcggtatt aaactagcga aaacagaagg cgctcaatac atcaaattaa ctcgtgatgg
     6661 aaaaggtgct cttgcattcg tacaagcgca attcgattaa ggctagagac tctgaaatag
     6721 tctcctatcg ttacggaaat cgctatggcg aatttcctat tattaattcg tcggtaaaaa
     6781 gatatcgttt ttacctcctc atgtcacaat tcggtgactt ggtacaagaa gtgagatgga
     6841 gaaggatggc tcactgactc ctctcctctc acttttactt tatttaaatc aagaaatagg
     6901 tgaaaaaaat gacaaaaaca cttccaaaag actttatttt tggtggcgca acagctgcct
     6961 atcaagcaga aggtgctaca catactgatg gtaaaggacc agtagcgtgg gataaatatc
     7021 ttgaagataa ctactggtac actgcagaac cagccagtga tttttacaat cgatatccag
     7081 ttgacctcaa gctagcagaa gagtatggtg tcaatggtat tcgaatttct attgcttggt
     7141 cacgtatttt cccgactggt tacggccaag taaatgctaa aggtgttgag ttttatcata
     7201 atttatttgc agagtgtcac aaacgtcatg ttgagccctt tgtaactctt catcactttg
     7261 acacgccaga agctctccac tcaaatggag acttcttaaa ccgtgaaaat atcgaacatt
     7321 ttgtagacta cgctgccttc tgttttgaag aatttccaga agtaaactat tggacaacct
     7381 ttaatgaaat tgggccaatt ggtgatggtc aatacttggt tgggaaattc cctccaggta
     7441 ttcagtacga ccttgccaaa gtcttccaat cgcaccacaa tatgatggtg tctcatgcgc
     7501 gtgcagttaa gctatataaa gataaaggct ataaaggcga aattggtgtt gttcacgctc
     7561 tgccaactaa gtatccttta gatcctaaaa atccgtcaga tgttcgtgca gctgagttgg
     7621 aagatattat tcacaataaa tttatcttgg atgcaactta tctaggtcgc tattcagctg
     7681 aaacgatgga aggtgtcaac catatcttat cagtcaatgg tggtagcttg gatcttcgtg
     7741 aagaagattt tacagcatta gaagcagcaa aagacttgaa tgatttcctt ggaatcaact
     7801 actatatgag tgactggatg gaagcctttg atggagaaac tgaaattatc cataatggta
     7861 agggtgagaa aggaagttct aaataccaaa tcaaaggtgt tggtcgtcgt gtagctcctg
     7921 attatgtacc acgtacggat tgggattgga ttatctaccc tcaaggttta tatgaccaaa
     7981 ttatgcgtgt gaagaaagat tatcctaact acaagaagat ttacatcact gaaaatggtc
     8041 tcggctataa agatgagttc gtcgataaca ctgtttatga tgatggacgt attgattatg
     8101 tgaaacaaca cttggaggtc ttgtctgatg cgattgcaga tggagcgaat gtaaaaggtt
     8161 acttcatttg gtcattgatg gacgtctttt catggtcaaa tggttatgaa aaacgttacg
     8221 gtctcttcta tgtagacttt gaaactcaag aacgttatcc gaagaaatca gctcactggt
     8281 acaagaaagt agcggaaact cagattatag actagtagaa ttagtcatta gatatagaat
     8341 tttagtgagt caaaaagatg ttcaaagatt ttatccaatc tatttatgaa aaagtttata
     8401 ttataaattt cgaaaaatgc tctcaaatac cgtgtttgac gagtgaagaa ttgaaaagtc
     8461 tatttttaaa ttttatcaat cctgaagaat gggatactat ctcctttgat tcagatttta
     8521 tgccatttca acaatcgtaa ccaatttctc aaaaaagtta aatcttatat ttagtactct
     8581 gcaaaactct tatctaatca cgttgcttat actcaatgaa aatcaaagag caactttaaa
     8641 ctaggaagcg agtcgcagat ttctcaatgc atagctttga ggaattgggc aaaaagtctt
     8701 tgatatagaa aaagcatagt atcaggtgtt tcaacacctg atactatgct ttttattgtg
     8761 ggaagattta ctttttttct tctgaaattg agttgttacc caggctcttt cagtttatta
     8821 aggcttgatg actttaatgt gtttagatag cttaaaaagg attgaatcac ttagtttaga
     8881 atctgaaaca atagtatcaa gatttgatac attataaaaa gtataaaaat caaacttatt
     8941 gaacttacta tgatctgcga gtaaatattt tttattagaa ttatttaaag cgatgcgttg
     9001 agcctctccc tcttcctcgc taaaagtagc tagagctccg ttttgaatac cattacagct
     9061 aacgaaagct ttagaaaatt ggagattaga gagattttgt agggtcaatg tgccaacaaa
     9121 agcacctgta atatcgcgat aatttccacc tatcaaaatc aaatctgtta attttcgttc
     9181 gcttaaaatc agaaaaacag gtagactgtt ggttacgacg cggatattgt caataggcaa
     9241 ctcacgcgca aaaaactcta atgttgttcc tggtccaatg aaaatagttt ctctttcttc
     9301 tactagactg cctgcaaaat gggctatttc ttgtttttct gccgtttgga gggcttgttt
     9361 ttcaatattt gatcgctcat tagtcaaaag ggagttggtt cgaagttttt cagctccacc
     9421 atgcacacga atcagcaaat ctttatcagc taattcctgt aaatagcgcc ttgcagtcat
     9481 atctgaaacg gctatttcgt ccataatctg tttaactgtt atggttcctt tactatttac
     9541 tatctctaaa attttggcta atttttcttg tttgagcata ttatcacctc gtttcctact
     9601 actatcttac cataaacaaa ctcatcattc aaatacaaaa acaacaaaat gaaacaaaaa
     9661 caaaaatatc gaagtttgtt ttcaaaactt tcgatatttt tgttgggtta taactttgat
     9721 gtttctagtt tactttttga tgattgagag tgatggagaa ttagtctaaa ccgtagttat
     9781 agtcatcgtc ttgcatggct tcaacttcgc caagaaggta accatttccg acttgagaga
     9841 agaagtcatg gttggaagtt cctgttgaaa taccgttcat aacgattggg ttgacatctt
     9901 cagctgaatc tgggaaaagt ggatcttgtc ccatgttcat gagagcttta ttggcattgt
     9961 agcgaaggaa ggttttaacc tcttcagtcc aaccaacacc gtcataaaga ctctctgtgt
    10021 agccttcttc attttcataa agagtataga gtaggtcgta catccattct ttgagttttt
    10081 cttgctcttc ttcaggcaat tcattgaaac caagttggaa tttgtaacca atgtaggttc
    10141 cgtgaacaga ctcgtcacga ataatcaatt taatgatttc tgcaacgttg gctagtttgt
    10201 tgttaccgag atagtagagg ggagtgaaga aaccagagta gaagaggaag gtttcgagga
    10261 agacgctggc aactttcttt tcaagtgggc tgccgtttag gtagatttcg ttgacaatct
    10321 cagccttctt ttgtaggtaa ggattggtat tggtccattc gaaaatttct tcaatctcag
    10381 ccttagtatt caaggtagaa aagattgatg agtaagattt agcgtggaca gattccataa
    10441 attggatgtt attgaaaaca gcttcctcat gtggtgtacg gatgtctgcg cgaagggctt
    10501 gaaccccagt ttcagattgc atagtgtcaa gaagggttaa accaccaaaa acttttccga
    10561 ccaagtcttt ctctttgtta gatagctttc tccagtcatc caagtcgttt gataagggaa
    10621 tacgtgtatc gagccaaaat tgctccgtca gtttttccca agttgatttg tcgatgacat
    10681 cttcgatggc attccagtta atggctttgt agtaagtttc catttaaaat ctctttctgt
    10741 gtttagtatt gcgaactcac aattatttct actttaccat aattctatag gagtatcgca
    10801 caaaaagtcg gaagcccgac ttttaaaatg ttacataaat tatgttatga catagtagat
    10861 ttgattttat cagtgctgct tagggaaaaa taatgtttct atgctagaaa ctaaatcaca
    10921 cagctttcac attggttggc gccgacttct ccaccgtcat ctgtaaaggt acggacgtag
    10981 tagatagact tgattccctt gttaaaggca tagttacgaa ggatggacaa gtcacgtgtc
    11041 gtttgtttat tttccctctt ccattcgtaa aggccttttg gaatgtcact acgcatgaag
    11101 agggtgagtg aaagtccttg atccacgtgt tcagtcgcag cagcgtaaac atcgatgact
    11161 ttacgcatat ccatatcgta ggcagaagtg tagtaaggaa tggtttctgt agacaagcca
    11221 gcagcagggt agtagatttt accaattttc ttctcttggc gttcttcgat acgttgcgta
    11281 atcgggtgga tagaagcaga aacgtcgttg atatagctga tagaaccatt tggcgctaca
    11341 gcaaggcgat tttggtggta aagaccatct tcttgaacct tgtcgcgaag ttcagcccaa
    11401 tcagcaacac cagggataaa gacatttttg aagagttctt taacacggtc tgatgttgga
    11461 acaaattcac cagttacata cttgtcaaag taacttccgt tagcatagtc tgatttttca
    11521 aagttgtgga aggtaatacc acgttcacgc gcaatattgt ttgactctac caaggtccag
    11581 tagttcataa gcataaagta gatgcttgta aattcaacag actcaggtga accatattca
    11641 atgagttgtt gggcaaggta gctgtgcagt cccatggcac cgagaccaaa ggtgtgggct
    11701 tggctatttc catggtcaat cgttggtaca gctacgatat gtgaactatc tgtaacgaaa
    11761 gtaagggcac gaaccatagc acggatagaa cgaccaaaat caggtgaagt catcatgtta
    11821 accacgttgg ttgaacccag gttacatgaa acatctgttc ccatttgaag gaattcttga
    11881 gcatcgttga tcaagcttgg ttcttgaact tgaagaatct cagaacacaa gttactcatg
    11941 ataatctttc catcaacagg atttgcacgg ttagccgtat cgatgttgac tacataagga
    12001 tagccagact cttgttgcaa tttagagatt tcagtttcca aatcccgcgc cttgattttt
    12061 gtcttgcgaa tatttggatt tgcgaccaat tcatcgtatt tttcagtaat gtcgatgtaa
    12121 ttgaatggca caccgtattc tttttctaca gagtaagggc tgaagaggta catttcttca
    12181 tttttacgag ccaattcgta gaatttatca ggtactacaa caccaagtga tagagtcttg
    12241 acacgtactt tttcatcagc gttttctttc ttagttgaaa ggaaagcgat gatatctggg
    12301 tgaaagacgt tgaggtagac aacaccggca ccttgacgtt gccccaattg gttggagtaa
    12361 gagaagctgt cttcaaaaag cttcataaca ggaacgacac ctgaagcagc tccttcatag
    12421 cctttgatag gtgcaccagc ttcacgaagg ttgctgaggg taattcccac accaccacca
    12481 atacgtgaaa gttgaagagc tgagttgata gaacgtccga tagagttcat atcatccgtc
    12541 acttggatta ggaaacaaga taccaactct ccacggcgag cacgtccagc attcaagaag
    12601 gaaggagtag caggttggta gcgttggtgg atgatttcat tggcaatatc gattgcaaca
    12661 gcttcattcc catcagcgaa ataaagggcg ttgaagaaga cacggtcttc catattttca
    12721 agatagtatt caccgtcatt agtctttaag gcatattgat tgtaaaattt ataagctgcc
    12781 atgaatgact tgaattggaa gttttggtct ttgataaatt gagctaattc ttccaagaac
    12841 tctggacggt atttcttgat aaaggctgtt tcgatgtagt tgtgttcaat gaggtaattg
    12901 attttgtctt tgattgaatc aaaaaccata gtgtttggaa ctacattttc tttaaagaaa
    12961 gcatccaagg cttccttgtc tttatgaagc atgatttgtc cattaacagg acggttaatt
    13021 tcgttattaa gacggaagta agtcacgtct tcaagatgtt ttaatcccat aaaatttccc
    13081 ttatctaatt acaaaagaaa ggcttctaag ttagccctaa aagcagtttc ttctggatga
    13141 tgtactaaga ttatgctaat tgtttcagtt ttcctggttg gaaacctgaa aagacttcag
    13201 ttggtgtttg gataacagga gctgcgctaa aaccgagctc tttaacttga tcgacgtact
    13261 caggttgctc atcaagattg atttcacgat aagagacatt attactgtcc aagaaacgct
    13321 tggtcatttt acattggaca caattgtttt tagaataaac ggttaccatt gtgtaactcc
    13381 tcttcaaaat ttaatactat cttagtatat cagaaaataa aattttgtca atgatttgaa
    13441 ctaaatatag tggtgttctt ttgttgtttt tatatataaa cacaatatat agtgtttgta
    13501 ttgtgaaata gcaatgatta tcctataaat tgtttttaaa gaaactatat cctgtgtttt
    13561 gttatctagg atagaagatt ttcagcaagt tatctgaaag gaaattgaag gaaaatccag
    13621 aaaatgcttg aaaaaaatcc tagaagatgg tataatacta aattgtaagg gttatcacat
    13681 ataactcaaa aaaagaaaga acaaaaggag agtcaaacta tggcttctaa agatttccac
    13741 gtagtggcag aaacaggtat tcacgcacgt ccagcaacat tgttggtaca aactgctagc
    13801 aaatttgctt cagatatcac tcttgagtac aaaggtaaat cagttaacct taaatcaatt
    13861 atgggtgtta tgagtcttgg tgttggccaa ggtgctgacg taactatctc agctgaaggt
    13921 gcagatgcag atgacgctat cgctgcaatc tcagaaacaa tggaaaaaga aggattggca
    13981 taagggaaat gacagaaatg cttaaaggaa tcgcagcatc tgacggtgtt gcagttgcaa
    14041 aagcatatct actcgttcag ccggatttgt catttgagac tattacagtc gaagatacaa
    14101 acgcagaaga agctcgcctt gatgccgctc tacaggcatc acaagacgag ctttctgtta
    14161 ttcgcgagaa agcagtaggt acgctcggtg aagaagcagc tcaagttttt gatgctcact
    14221 taatggttct tgctgaccca gaaatgatca gccaaatcaa ggaaactatc cgtgcgaaga
    14281 aagtgaatgc agaagcaggt ctgaaagaag ttacagatat gtttatcact atctttgaag
    14341 gcatggaaga caacccatac atgcaagaac gcgcagcgga tatccgcgac gtgacaaaac
    14401 gtgtattggc aaaccttctt ggtaaaaaat tgccaaaccc agcttctatt aatgaagaag
    14461 tgattgtgat tgcgcatgac ttgacaccat ctgatacagc tcaattggac aaaaactttg
    14521 taaaagcttt tgtaaccaac attggtggac gtacaagcca ctcagctatc atggcacgta
    14581 cacttgaaat tgctgctgta ttaggtacaa ataacatcac tgaaatcgtt aaagacggtg
    14641 acatccttgc tgttaacggg atcactggag aagtgattat caacccaaca gatgaacaag
    14701 cggcagaatt taaagcagct ggtgaagcct atgcgaaaca aaaagctgaa tgggcacttt
    14761 tgaaagatgc tcaaacagtg actgctgacg gtaaacactt cgagttggct gccaatattg
    14821 gtactccaaa agacgttgaa ggtgttaaca acaacggtgc agaagctgtt ggactttacc
    14881 gtacagagtt cttgtacatg gattctcaag acttcccaac tgaagatgag cagtatgaag
    14941 catacaaggc tgttcttgaa ggaatgaacg gtaaacctgt tgtcgttcgt acaatggata
    15001 tcggtggaga taaggaactt ccttacttcg atatgcctca cgaaatgaac ccattccttg
    15061 gattccgtgc tcttcgtatc tctatctctg agactggaga tgctatgttc cgcacacaaa
    15121 tccgtgctct tcttcgtgcg tctgttcacg gtcaattgcg tatcatgttc ccaatggttg
    15181 cgctcttgaa agaattccgt gcagcgaaag cagtctttga tgaagaaaaa gcaaaccttc
    15241 ttgctgaagg tgttgcagtt gcggataaca tccaagttgg tatcatgatc gagattcctg
    15301 cagcggctat gcttgcagac caatttgcta aagaagttga cttcttctca attggtacaa
    15361 acgacttgat ccaatataca atggcagcag accgtatgaa cgaacaagtt tcataccttt
    15421 accaaccata caacccatca atcctacgct tgattaacaa tgtgatcaaa gcagctcacg
    15481 ctgaaggtaa atgggctggt atgtgtggtg agatggctgg tgaccaacaa gctgttccac
    15541 ttcttgtcgg aatgggcttg gatgagttct ctatgtcagc aacatctgta cttcgtacac
    15601 gcagcttgat gaagaaactc gacacagcta agatggaaga gtacgcaaac cgtgccctta
    15661 cagaatgctc aacaatggaa gaagttcttg aacttcaaaa agaatacgtt aattttgatt
    15721 aatcgaaaag tccctgcaac tcagttacag ggactttttt tgatatttta aaaagaattt
    15781 tcaagaaaat ctttcttata aaaagtccaa ccttgaaaaa gtagtggtca gaacaaaaaa
    15841 tacttaaatg gttcataaaa ttcttgacaa gttggagatt taggagtaaa ctattaacca
    15901 gttaagtaat agagaggagt ttctgcaatt tagaaatgaa ttgcaactag aaatatcaaa
    15961 tagaaagaga gtttcgatga aaattaataa gaaatacctt gttggttctg cggcagcttt
    16021 gattttaagt gtttgttctt acgagttggg actgtatcaa gctagaacgg ttaa
//
LOCUS       DAVBBO010000050        15041 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ST1
            SAMEA2066453-rid20184263.denovo.050, whole genome shotgun sequence.
ACCESSION   DAVBBO010000050 DAVBBO010000000
VERSION     DAVBBO010000050.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2066453
            Sequence Read Archive: ERR351777
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 15041)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 15041)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980402.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980402.1
            Genome Coverage       :: 176x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:17:33
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,141
            CDSs (total)                      :: 2,104
            Genes (coding)                    :: 1,953
            CDSs (with protein)               :: 1,953
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 16S)
            partial rRNAs                     :: 1 (23S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 151
            CDSs (without protein)            :: 151
            Pseudo Genes (ambiguous residues) :: 0 of 151
            Pseudo Genes (frameshifted)       :: 73 of 151
            Pseudo Genes (incomplete)         :: 76 of 151
            Pseudo Genes (internal stop)      :: 40 of 151
            Pseudo Genes (multiple problems)  :: 32 of 151
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15041
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2066453-rid20184263.denovo.050"
                     /strain="ST1"
                     /db_xref="taxon:1313"
     gene            <1..338
                     /locus_tag="VQU30_001648"
     CDS             <1..338
                     /locus_tag="VQU30_001648"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HET2447721.1"
                     /translation="AGLTNGELIAPMTYEEMMTSDFFEAWFQKFLLPTLTTPSAIIMD
                     NARFHRMGKLELLCEEFGHKLLPLPPYSPEYNPIEKTWAHIKKHLKKVLPSCCNTFYE
                     ALLSCSCFN"
     gene            complement(545..2803)
                     /locus_tag="VQU30_001649"
     CDS             complement(545..2803)
                     /locus_tag="VQU30_001649"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398543.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit"
                     /protein_id="HET2447722.1"
                     /translation="MLCQNCKINDSTIHLYTNLNGKQKQIDLCQNCYKIIKTDPNNSL
                     FKGMTDLNNRDFDPFGDFFNDLNNFRPSSNTPPIPPTQSGGGYGGNGGYGSQNRGSAQ
                     TPPPSQEKGLLEEFGINVTEIARRGDIDPVIGRDDEIIRVIEILNRRTKNNPVLIGEP
                     GVGKTAVVEGLAQKIVDGDVPHKLQGKQVIRLDVVSLVQGTGIRGQFEERMQKLMEEI
                     RKREDIILFIDEIHEIVGAGSASDGNMDAGNILKPALARGELQLVGATTLNEYRIIEK
                     DAALERRMQPVKVDEPTVDETITILKGIQKKYEDYHHVQYTDAAIEAAATLSNRYIQD
                     RFLPDKAIDLLDEAGSKMNLTLNFVDPKVIDQRLIEAENLKSQATREEDFEKAAYFRD
                     QIAKYKEMQKKKITDQDTPIISEKTIEHIIEQKTNIPVGDLKEKEQSQLIHLAEDLKS
                     HVIGQDDAVDKIAKAIRRNRVGLGTPNRPIGSFLFVGPTGVGKTELSKQLAIELFGSA
                     DSMIRFDMSEYMEKHSVAKLVGAPPGYVGYDEAGQLTEKVRHNPYSLILLDEVEKAHP
                     DVMHMFLQVLDDGRLTDGQGRTVSFKDAIIIMTSNAGTGKTEASVGFGAAREGRTNSV
                     LGELGNFFSPEFMNRFDGIIEFKALSKDNLLQIVELMLADVNKRLSSNNIRLDVTDKV
                     KEKLVDLGYDPKMGARPLRRTIQDYIEDTITDYYLENPSEKDLKAVMTSKGNIQIKSA
                     KKAEVKSSEKEK"
     gene            complement(3032..3262)
                     /locus_tag="VQU30_001650"
     CDS             complement(3032..3262)
                     /locus_tag="VQU30_001650"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005592360.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YkuJ family protein"
                     /protein_id="HET2447723.1"
                     /translation="MESHLVRIINRLEAMANDGGNLKRNFEREGVVVAEVAYSHDEEN
                     GPIFTLRDVEDRETYTFDSIDLIAMEIYELLY"
     gene            3452..4135
                     /locus_tag="VQU30_001651"
     CDS             3452..4135
                     /locus_tag="VQU30_001651"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001011621.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HET2447724.1"
                     /translation="MNFSFLPKYLPYFNYGAVVTILISICVIFLGTILGVVLAFGQRS
                     KFKPLVWLANLYVWIFRGTPMMVQIMIAFALMHINAPTIQIGILGVDFSRLIPGILII
                     SMNSGAYVSEIVRAGINAVPKGQLEAAYSLGIRPKNAMRYVILPQAVKNILPALGNEF
                     ITIIKDSSLLSAIGVMELWNGATTVSTTTYLPLTPLLFAAFYYLIMTSILTVALKAFE
                     KHMGQGDKK"
     gene            4135..4869
                     /locus_tag="VQU30_001652"
     CDS             4135..4869
                     /locus_tag="VQU30_001652"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000140960.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HET2447725.1"
                     /translation="MTETLIKIENLHKSFGKNEVLKGINLEIKRGEVVVIIGPSGSGK
                     STLLRSMNLLEEATKGKVIFEGVDITDKKNDLFAMREKMGMVFQQFNLFPNMTVMENI
                     TLSPIKTKGESREVAEKRAQELLEKVGLPDKADAYPQSLSGGQQQRIAIARGLAMEPD
                     VLLFDEPTSALDPEMVGEVLAVMQDIAKSGMTMVIVTHEMGFAREVADRVIFMADGVV
                     VEDGTPEQIFEQTQEQRTKDFLSKVL"
     gene            5023..5880
                     /locus_tag="VQU30_001653"
     CDS             5023..5880
                     /locus_tag="VQU30_001653"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000192112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional methylenetetrahydrofolate
                     dehydrogenase/methenyltetrahydrofolate cyclohydrolase"
                     /protein_id="HET2447726.1"
                     /translation="MTQIIDGKALAAKLQGQLAEKTAKLKEETALVPGLVVILVGDNP
                     ASQVYVRNKERSALAAGYRSEVVRVPETITQEELLDLIAKYNQDPAWHGILVQLPLPK
                     HIDEEAVLLAIDPEKDVDGFHPLNMGRLWSGHPVMIPSTPAGIMEMFHEYGIDLEGKN
                     AVVIGRSNIVGKPMAQLLLAKNATVTLTHSRTHNLAKVAAKADILVVAIGRAKFVTAD
                     FVKPGAVVIDVGMNRDENGKLCGDVDYEAVAPLASHITPVPGGVGPMTITMLMEQTYQ
                     AALRTLDRK"
     gene            6022..6894
                     /locus_tag="VQU30_001654"
     CDS             6022..6894
                     /locus_tag="VQU30_001654"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000864675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-hydrate dehydratase"
                     /protein_id="HET2447727.1"
                     /translation="MKVINQTLLEKVIIERSRSSHKGDYGRLLLLGGTYPYGGAIIMA
                     ALAAVKSGAGLMTVGTDRENIPALHSHLPEPMAFSLQDQQLLKEQLEKAEVILLGPGL
                     GDNAFGEDLVKQVFAGLKQNQILIVDGGALTILARTSLSFPSSQLILTPHQKEWEKLS
                     GITIEKQKEDATASVLTSFPQGTILVEKGPATRIWEVGQSDYYQLQVGGPYQATGGMG
                     DTLAGMIAGFVGQFRQASLYERVAVATHLHSAIAQELSQENYVVLPTEISRYLPKIMK
                     IICQQERVSKDKLV"
     gene            7176..7859
                     /gene="rpiA"
                     /locus_tag="VQU30_001655"
     CDS             7176..7859
                     /gene="rpiA"
                     /locus_tag="VQU30_001655"
                     /EC_number="5.3.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000429260.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribose-5-phosphate isomerase RpiA"
                     /protein_id="HET2447728.1"
                     /translation="MENLKKMAGIKAAEFVSDGMVVGLGTGSTAYYFVEEIGRRIKEE
                     GLQITAVTTSSVTTKQAEGLNIPLKSIDQVDFVDVTVDGADEVDSQFNGIKGGGGALL
                     MEKVVATPSKEYIWVVDESKLVEKLGAFKLPVEVVQYGAEQVFRHFERAGYKPSFREK
                     DGQRFVTDMQNFIIDLALDVIENPIAFGQELDHVVGVVEHGLFNQMVDKVIVAGRDGV
                     QISTSKKGK"
     gene            7873..9084
                     /locus_tag="VQU30_001656"
     CDS             7873..9084
                     /locus_tag="VQU30_001656"
                     /EC_number="5.4.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004259464.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopentomutase"
                     /protein_id="HET2447729.1"
                     /translation="MSKFNRIHLVVLDSVGIGAAPDANNFVNAGVPDGASDTLGHISK
                     TVGLNVPNMAKIGLGNIPRETPLKTVAAESNPTGYATKLEEVSLGKDTMTGHWEIMGL
                     NITEPFDTFWNGFPEEILTKIEEFSGRKVIREANKPYSGTAVIDDFGPRQMETGELII
                     YTSADPVLQIAAHEDIIPLDELYRICEYARSITLERPALLGRIIARPYVGEPGNFTRT
                     ANRRDLAVSPFSPTVLDKLNEAGIDTYAVGKINDIFNGAGINHDMGHNKSNSHGIDTL
                     LKTMGLAEFEKGFSFTNLVDFDALYGHRRNAHGYRDCLHEFDERLPEIIAAMRENDLL
                     LITADHGNDPTYAGTDHTREYIPLLAYSPAFKGNGLIPVGHFADISATVADNFGVETA
                     MIGESFLDKLV"
     gene            9086..9628
                     /locus_tag="VQU30_001657"
     CDS             9086..9628
                     /locus_tag="VQU30_001657"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1697 domain-containing protein"
                     /protein_id="HET2447730.1"
                     /translation="MTRYALLVRGINVGGKNKVVMAELRQELTNLGLEKVESYINSGN
                     IFFTSIDSKAQLVEKLETFFAVHYPFIQSFSLLSLEDFEAELENLPAWWSRDLARKDF
                     LFYTEGLDVDQVIATVESLELKDEVLYFGKLGIFWGKFSEESYSKTAYHKYLLKVPFY
                     RHITIRNAKTFDKIGQMLKK"
     gene            9644..10453
                     /locus_tag="VQU30_001658"
     CDS             9644..10453
                     /locus_tag="VQU30_001658"
                     /EC_number="2.4.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="purine-nucleoside phosphorylase"
                     /protein_id="HET2447731.1"
                     /translation="MTFLNKIHETATFLKEKGIAAPEFGLILGSGLGELAEEIENPVV
                     VDYAEIPNWGRSTVVGHAGKLVYGELAGRKVLALQGRFHFYEGNPLEVVTFPVRVMKV
                     LGCEGVIVTNAAGGIGFGPGTLMAISDHINMTGQNPLMGENLDDFGPRFPDMSRAYTP
                     EYRATAHEVAKKLNIKLDEGVYIGVTGPTYETPAEIRSYKTLGADAVGMSTVPEVIVA
                     AHSGLKVLGISCITNFAAGFQEELNHEEVVEVTERVKGDFKGLLKAILAEL"
     gene            10929..11909
                     /locus_tag="VQU30_001659"
                     /pseudo
     CDS             10929..11909
                     /locus_tag="VQU30_001659"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001855254.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="discoidin domain-containing protein"
     gene            11934..12446
                     /locus_tag="VQU30_001660"
     CDS             11934..12446
                     /locus_tag="VQU30_001660"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001275913.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hemolysin"
                     /protein_id="HET2447732.1"
                     /translation="MSAQITINHKKARYVRIELEGYNALSLAEVEVFRFIATNAETAT
                     QVSKPVQPISQTPVKDKTLTIQHSGAYIARYSITWEEVPVDKDGNQVVRSHSWEGNGR
                     NQTAGFVLNLPIKENMRNLRVKIEKKTGLLWNRWQTIYENRPISAQPHRKITHWGTTL
                     NSKVSDDDVL"
     gene            13093..13803
                     /gene="deoD"
                     /locus_tag="VQU30_001661"
     CDS             13093..13803
                     /gene="deoD"
                     /locus_tag="VQU30_001661"
                     /EC_number="2.4.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="purine-nucleoside phosphorylase"
                     /protein_id="HET2447733.1"
                     /translation="MSIHIAAQQGEIADKILLPGDPLRAKFIAENFLDDAVCFNEVRN
                     MFGYTGTYKGHCVSVMGTGMGMPSISIYARELIVDYGVKKLIRVGTAGSLNEEVHVRE
                     LVLAQAAATNSNIVRNDWPQYDFPQIASFDLLDKAYHIAKKLGMTTHVGNVLSSDVFY
                     SNYFEKNIELGKWGVKAVEMEAAALYYLAAQYHVDALAIMTISDSLVNPDEDTTAEER
                     QNTFTDMMKVGLETLIAE"
     gene            complement(13826..14350)
                     /locus_tag="VQU30_001662"
     CDS             complement(13826..14350)
                     /locus_tag="VQU30_001662"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000684222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topology modulation protein"
                     /protein_id="HET2447734.1"
                     /translation="MKIAIIGYSGSGKSTIAEKLSNYYSIPKLHMDTLQFQPGWQDSD
                     CEWMLTEIKNFLTKHKAWVIDGNYSWCYYQERMQEADQIIFLNFSPLTCLFRAFKRYL
                     KYRGKVRESMAADCPERFEWEFIRWILWDGRSKTQKENYQKLCQEYSHKVTILRNQRE
                     LDQFLDKKRKSYNS"
     gene            complement(14403..14639)
                     /locus_tag="VQU30_001663"
     CDS             complement(14403..14639)
                     /locus_tag="VQU30_001663"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001274003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S20"
                     /protein_id="HET2447735.1"
                     /translation="MANIKSAIKRAELNVKQNEKNSAQKSAMRTAIKAFEANPSEELF
                     RAASSAIDKAETKGLIHKNKASRDKARLSAKLAK"
     gene            complement(14707..>15041)
                     /locus_tag="VQU30_001664"
     CDS             complement(14707..>15041)
                     /locus_tag="VQU30_001664"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004261526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="type I pantothenate kinase"
                     /protein_id="HET2447736.1"
                     /translation="NVFQNPQNDRLYITDFFDFSIYVDAGVDDIESWYLDRFLKMLSL
                     AQNDPDSYYYRFTQMPIGEVESFAHQVWISINLTNLQNYIEPTRNRAEVILHKSKNHE
                     IDEIYLKK"
BASE COUNT         4427 a         2756 c         3351 g         4507 t
ORIGIN      
        1 ttgcaggtct aacaaatggt gagttaatcg ctccaatgac ttacgaagag atgatgacga
       61 gcgacttttt tgaagcatgg tttcagaagt ttctcttacc aacattaacc acaccatcgg
      121 ctattattat ggataatgca agattccata gaatggggaa gctagaactt ttatgcgaag
      181 agtttgggca taaactttta cctcttcctc cctactcacc tgagtacaat cctattgaga
      241 aaacatgggc tcatatcaaa aagcacctca aaaaggtatt accaagttgt tgcaatacct
      301 tttacgaggc tcttttgtcc tgctcttgtt tcaattgact atagcagatt gaaataagat
      361 gagaacaaat cgattgggaa agtaaaatta atttctataa atgttttagc aattgtttcg
      421 tactatttca gattcagtct actatatatc ataatggaca aagggcaagc tgtcaagaaa
      481 ttacagttat tttagtaaaa aaagaagcag aaaaatttaa ttttctactc cttttctata
      541 ggatttattt ttctttttca gaacttttaa cttcagcttt tttggcagat ttaatctgaa
      601 tgtttccctt gctagtcata actgctttga gatctttttc gcttggattt tcaaggtagt
      661 agtcagtgat tgtgtcctca atatagtctt gaatagtccg acgaagtggg cgtgctccca
      721 tttttggatc ataacctagg tcaaccaact tttccttgac cttgtcagtt acatccaaac
      781 gaatgttgtt gctagagagg cgcttgttaa catctgctag catgagctcg acaatctgaa
      841 ggaggttatc cttgctgaga gccttaaatt cgataatgcc atcaaaacgg ttcataaact
      901 ctgggctaaa gaagttaccg agttcaccga ggacagaatt ggtacgtcct tctctagcag
      961 caccaaatcc aacgctagct tcggtctttc ctgtacctgc atttgaggtc atgataatga
     1021 tggcatcctt gaagctaacg gtgcgtcctt gcccgtctgt caaacgacca tcgtccaaga
     1081 cttgaagaaa catgtgcata acatctgggt gagctttttc cacttcatcg agaaggatga
     1141 gagaatatgg attgtggcga actttttcag ttaattgacc agcctcatca tagccaacat
     1201 aacctggagg agcgccgacc aacttagcca cactatgttt ttccatgtat tcactcatat
     1261 caaagcgaat catactatca gcagaaccaa aaagttcgat agccagttgt ttggaaagtt
     1321 ctgtcttacc gacaccagtt ggcccaacga agaggaagct tccgattggg cggttagggg
     1381 taccaagtcc gacacgatta cggcgaatag ccttggcaat cttatcgact gcatcatctt
     1441 ggccaataac atgagacttg agatcttcgg ctagatggat gagttgagat tgttctttct
     1501 ctttcaaatc accaacaggg atattggttt tctgctcgat aatgtgctca atagttttct
     1561 cgctgatgat aggagtatcc tggtctgtga tctttttctt ttgcatttcc ttatacttgg
     1621 caatctggtc gcggaagtag gccgccttct caaaatcttc ttctcgtgta gcttgagact
     1681 tgagattttc agcctcaatc aagcgctgat caattacttt aggatccaca aaattcaagg
     1741 tcaagttcat cttagaacca gcttcatcta ggaggtcaat ggccttgtca ggcaagaagc
     1801 gatcttggat gtagcgattg gaaagagttg cagctgcttc aatcgcagca tctgtatatt
     1861 gaacgtggtg gtaatcttcg tatttctttt gaatcccttt gagaatagtg attgtttcgt
     1921 ccaccgttgg ttcatcgact ttaacaggct gcatacgacg ctcgagggca gcatcctttt
     1981 caatgatacg gtattcattg agggtagtag caccgactag ttgcagttct ccacgagcaa
     2041 gggctggctt gaggatattt cctgcgtcca tattaccatc actcgcagaa ccagcaccaa
     2101 caatttcatg gatttcatcg ataaagagga tgatgtcttc acgtttgcga atttcttcca
     2161 tgagtttttg catgcgttct tcaaattgtc ctcgaatccc cgttccttga actaagctaa
     2221 ccacatccag acggatgact tgtttacctt ggagtttatg tggcacatcg ccatcgacaa
     2281 ttttctgagc tagaccttcg acaacggccg tttttccgac accaggttca ccgataagga
     2341 caggattatt cttggttcta cgattgagaa tctcgatgac acggataatc tcatcgtcgc
     2401 gcccaataac ggggtcaatg tctccacgac gggcaatttc agttacatta ataccaaatt
     2461 cttccagcag gcctttttct tggctaggtg gcggagtttg agcagatcca cgattttggg
     2521 aaccataacc gccgtttcca ccgtaacctc cacctgattg ggttggggga ataggaggag
     2581 tattgctaga aggtctgaaa ttgtttagat cattgaagaa atcaccaaag ggatcgaagt
     2641 cacgattgtt cagatccgtc atacctttga agaggctatt gttaggatct gttttgataa
     2701 tcttatagca gttttgacag aggtcaattt gtttttgttt tccattgaga ttggtgtaaa
     2761 gatgaattgt tgagtcgtta attttacagt tttgacaaag catacatcta cctcatttct
     2821 ttctttagcc tgacttgttt aaaggtcaaa aatagtcaaa ttctatactc tcattataac
     2881 aggattgggg tgtaaagcaa gtaaaaagat tgaagctttg agaagttgtt acaatgaaaa
     2941 tttttgtgaa tttggactat aaaaaaatcc tatttgtgag acaaaaagga ttttacttag
     3001 acatgcaggg acaatcccag cttgttttag attagtagag aagttcgtaa atttccattg
     3061 cgattaagtc aatgctatca aacgtatacg tttcgcgatc ttctacgtca cgaagggtaa
     3121 agattgggcc gttttcttcg tcgtggctgt acgcaacttc tgcaacaaca actccttcgc
     3181 gttcaaaatt acgttttaaa tttccgccat cgtttgccat tgcttcaagg cggttgatga
     3241 ttctaaccaa atgtgattcc attttgattc tccttcattt cttatcgtta ctattttacc
     3301 ataaaggagg ccaacttgac tagaaaaaac taagatttct cgctaattct gctagtttaa
     3361 agatttttaa ataaattgga taaaaaattt aaattttaat tcaaaacatg ttataatcat
     3421 acagtattct attttagaaa gcagtgtgac tatgaatttt tcttttttac ctaagtattt
     3481 accttatttt aactatgggg ctgttgtgac gattcttatt tctatctgtg ttatcttttt
     3541 gggaactatt ttgggtgttg tcttggcttt tgggcaacgt tcaaagttta aaccgcttgt
     3601 ttggttggcc aacttgtacg tttggatttt ccgtgggaca ccgatgatgg ttcaaattat
     3661 gattgccttt gctcttatgc atatcaatgc tccgactatt cagattggaa ttttaggtgt
     3721 tgatttttcg cgtctgattc cagggatttt gattatctct atgaatagtg gtgcttatgt
     3781 ttcggagatt gttcgtgccg gaatcaatgc ggttccaaaa ggtcagctag aggcggctta
     3841 ttcgctaggg attcgtccta aaaatgcgat gcgttatgtg attttgccac aagcagtcaa
     3901 aaatatcttg ccagcattgg ggaacgaatt tatcaccatt atcaaggaca gctccctctt
     3961 atcagctatt ggggtcatgg agttgtggaa tggggctaca acagtttcta caacaaccta
     4021 tctaccttta acaccacttt tatttgcagc attttactac ttgattatga cctctattct
     4081 gacagtagcc ttgaaagctt ttgaaaaaca tatgggacaa ggagataaga aataatgaca
     4141 gaaaccttga taaaaattga aaatttacat aaatcttttg gaaagaatga agtattgaag
     4201 ggcatcaacc tcgagattaa aagaggagaa gttgtcgtta tcatcggtcc ttcagggagt
     4261 gggaaatcta ccttgcttcg ctctatgaat ttgttggagg aagcaaccaa ggggaaggtt
     4321 atctttgagg gagtcgatat tacggacaag aagaatgacc tgtttgccat gcgtgagaag
     4381 atgggcatgg ttttccaaca atttaacctc tttcctaata tgactgtgat ggaaaatatt
     4441 accttgtcac ctatcaagac taaaggtgaa agcagggaag ttgctgagaa gagagcccaa
     4501 gagcttttgg aaaaagttgg tttgccagat aaggcagacg cttatccaca gagtctgtcg
     4561 ggtgggcaac aacaacggat tgccatcgcg cgtgggttgg ctatggaacc agatgttttg
     4621 ctctttgacg aaccaacttc agccttggat cctgaaatgg taggtgaggt attggctgtt
     4681 atgcaagaca ttgccaagtc agggatgact atggttatcg taacacatga gatgggattt
     4741 gcccgtgagg tggcagatcg tgttatcttt atggcagacg gtgtggttgt tgaagatggg
     4801 acacctgagc agatttttga acaaacccaa gaacaacgga ctaaagattt cttgagtaag
     4861 gttttataat ctattttaaa atttcaagac aagattagtg aaaagttcaa ccagagcttt
     4921 ttcttatagt ttgaaactat aggataacct aggaaagaag tgttagaggg cactagcagt
     4981 ttttggtata atggaagata tttgaaagaa aagagaagtg atatgacaca gattattgat
     5041 gggaaagctt tagcggccaa attgcagggg cagttggctg aaaagactgc aaaattaaag
     5101 gaggaaacag ctctagtgcc tggtttggta gtgattttgg ttggggataa tccagccagc
     5161 caagtctacg ttcgcaacaa ggagaggtca gctcttgcgg ctggttaccg tagcgaagta
     5221 gtgcgagttc cagagaccat tactcaagag gaattgttag acctgattgc taaatataat
     5281 caggatccag cttggcatgg gattttggtc cagttgccat taccaaaaca tatcgatgaa
     5341 gaggcggttt tattagccat tgacccagaa aaggatgtgg atggtttcca tcccctaaac
     5401 atgggacgtc tttggtctgg acatccagtc atgattccct cgacacctgc aggaattatg
     5461 gaaatgtttc atgaatatgg gattgacttg gaaggtaaaa atgcggtcgt aatcggtcgt
     5521 tcaaatatcg ttggaaaacc tatggctcag cttcttttgg ctaaaaatgc gacagtaacc
     5581 ttgacccact cacgaactca taatcttgcc aaggtggctg ctaaagcaga tattcttgta
     5641 gtcgcaatcg gccgcgccaa gtttgtgact gctgactttg tcaaaccagg tgcggttgtc
     5701 attgacgttg ggatgaatcg agatgaaaat gggaagctct gtggagatgt tgattatgag
     5761 gcagttgcac cacttgctag ccatatcacg ccagtccctg gaggtgtcgg tcctatgacc
     5821 attaccatgc tgatggagca aacttatcaa gcagcacttc ggacattgga tagaaaataa
     5881 gagaagcatt cgattaatag agtgtatttt ctatagctat atctaaaatg gcagaaatga
     5941 atattaaatt ttagatataa gattacaaaa ggaggtctgc gtctcctttt tattgtataa
     6001 taaaagtgag aggaaaaaag gatgaaagtg attaatcaaa ccttattaga aaaagttatt
     6061 attgaacgtt ctcgttcaag tcataaagga gattatggtc gtctgctgct gcttggtggt
     6121 acttatcctt atggaggtgc catcatcatg gctgctttag cagctgtaaa aagcggtgca
     6181 ggattgatga ccgttggaac ggacagggaa aatatcccgg ctctgcacag ccatttacct
     6241 gagcctatgg ccttttctct tcaagaccag caattgttaa aagagcaatt ggagaaggca
     6301 gaagttatct tgctggggcc tggtttagga gacaatgctt ttggagaaga tttagttaaa
     6361 caggtctttg ctggcttaaa acagaatcag attttgattg tagacggagg tgccttgacc
     6421 attcttgcta ggacaagttt gtcatttccc tcaagccagc ttatcctaac tcctcaccaa
     6481 aaagaatggg aaaaattatc tggaattacg attgaaaagc aaaaggaaga tgcaacggct
     6541 agtgttctga cttccttccc tcaaggaaca attttggtgg agaaaggccc agctactcgt
     6601 atttgggaag ttggccaatc tgattattac cagttacagg ttggtggtcc ttatcaggcg
     6661 actgggggaa tgggagatac tctggctggg atgatcgcag gatttgtagg ccaattccga
     6721 caggccagtc tctacgagcg tgtggcagta gcgacccatc ttcattcagc catagcccaa
     6781 gaactatctc aagaaaatta tgtggtctta ccgacggaaa tcagcaggta tcttcccaaa
     6841 ataatgaaaa ttatttgtca acaagagagg gtaagcaaag ataaacttgt ttaaaataga
     6901 cagataaatc tacttccttc tcttaattta tgattcttga aatgcgcctg ctttaaggct
     6961 aaactagacg tatcaaagtt aagagtttgt ttttgtaact ggaaagagat gaacaaatca
     7021 aatacataaa agataaactc atttttattc gttttgtaaa aataaaatgc atatttttaa
     7081 agaaagattg atgaaaaatg tagatttgat gtttttactt gaataaaaag cggtttcata
     7141 gtaaaataag aactgagaat gatggaggta aatcggtgga aaatctgaag aaaatggcag
     7201 gtatcaaggc tgctgagttc gtgagcgatg gaatggtcgt tggacttgga acaggctcga
     7261 ctgcctatta ttttgtcgaa gaaatcggtc gtcgtatcaa ggaagaagga ttgcagatta
     7321 cagctgtaac aacttctagt gtgaccacta aacaggcaga aggccttaat atcccgctca
     7381 agtctattga ccaagtagac tttgtcgatg tgacggttga tggcgcggat gaagtggata
     7441 gtcagtttaa tggaatcaaa ggcggtggtg gtgcccttct catggaaaag gtggtcgcaa
     7501 caccatcaaa agaatacatt tgggtggtgg atgaaagcaa gctggtcgaa aaactaggtg
     7561 cttttaaatt gccagtagaa gtggttcagt atggtgcaga gcaggtcttt cgtcattttg
     7621 aacgagctgg ctacaaacca agtttccgtg aaaaagacgg tcaacgtttt gtgacggata
     7681 tgcagaattt tatcattgac ctcgccttgg atgtcattga aaatccaatt gcttttggac
     7741 aagaattgga ccatgtcgtt ggtgttgtgg agcatggttt attcaaccaa atggtggata
     7801 aggtaatcgt tgctggacga gatggagttc agatttcaac ttcaaaaaaa ggaaaataga
     7861 agggggcata agatgtctaa atttaatcgt attcatttgg tggtactgga ttctgtagga
     7921 atcggtgcag caccagatgc taataacttt gtcaatgcag gggttccaga tggagcttct
     7981 gacacactgg gacacatttc aaaaacagtt ggtttgaatg tcccaaacat ggctaaaata
     8041 ggtcttggaa atattcctcg tgaaactcct cttaagactg tagcagctga aagcaatcca
     8101 actggatatg caacaaaatt agaggaagta tctcttggta aggatactat gactggacac
     8161 tgggaaatca tgggactcaa cattactgag cctttcgata ctttctggaa cggattccca
     8221 gaagaaatcc tgacaaaaat cgaagaattc tcaggacgca aggttattcg tgaagccaac
     8281 aaaccttatt caggaacggc tgttatcgat gattttggac cacgtcagat ggaaactgga
     8341 gagttgatta tctatacttc agctgaccct gttttgcaga ttgctgccca cgaagacatt
     8401 attcctttgg atgaattgta ccgtatctgt gaatacgctc gttcgattac ccttgagcgt
     8461 cctgcccttc ttggtcgcat cattgctcgc ccttatgtag gtgaaccagg taacttcact
     8521 cgtacggcaa accgtcgtga cttggctgta tctccatttt ccccaactgt tttggataaa
     8581 ttgaatgagg ctggtatcga tacttatgct gtgggtaaaa tcaacgatat ctttaacggt
     8641 gctggtatca accatgacat gggtcacaac aagtcaaata gtcatggaat tgatacacta
     8701 ttgaagacta tgggacttgc tgagtttgaa aaaggattct cattcacaaa cctagttgac
     8761 tttgatgccc tttacggcca tcgtcgtaat gctcacggtt accgtgattg cttgcatgag
     8821 tttgatgaac gcttacctga aattatcgca gctatgagag agaatgacct tctcttgatt
     8881 actgcggacc atggaaatga cccaacgtat gcaggaacgg atcacactcg ggaatatatt
     8941 ccattgttgg cctatagccc tgcctttaaa ggaaatggtc tcattccagt aggacatttt
     9001 gcagatattt cagcgactgt tgccgataac tttggtgtgg aaactgctat gattggggaa
     9061 agtttcttag ataaattggt ataagatgac gcgctatgct ttgctggtga gaggtatcaa
     9121 tgttggtggt aagaataagg tcgtcatggc ggagcttcgt caagaattga caaacttggg
     9181 actggaaaag gttgagagct acatcaatag tggcaatatt ttctttactt cgatagattc
     9241 caaagcccaa ttggttgaaa agctagagac tttctttgca gtccattatc catttattca
     9301 gagcttttct ttactgagtc tagaggactt tgaggcggaa cttgaaaatc taccagcttg
     9361 gtggagcaga gacttggcac gaaaagattt tctcttttac actgagggtt tggatgtgga
     9421 ccaagtcatc gcgacagttg aaagtttaga gctgaaagat gaagtgcttt attttggaaa
     9481 acttgggatt ttctggggga aattttctga agaatcctat tctaagactg cctatcataa
     9541 gtacttgctg aaggtgcctt tctaccgcca cattactatt cgtaatgcta aaacctttga
     9601 caaaattggt caaatgctaa aaaaataata aaggagacac acaatgacat ttttaaacaa
     9661 aatccatgaa actgctactt tcctgaaaga aaagggaatt gcagcccctg agttcggtct
     9721 aatccttgga tcaggacttg gagaattggc agaagaaatc gaaaatccag ttgtagtaga
     9781 ctatgctgag attccaaact ggggccgttc aacagtagtc ggtcatgctg gtaaattggt
     9841 atatggtgaa ctggcaggtc gcaaggtctt ggctcttcaa gggcgtttcc atttctatga
     9901 agggaatcct ctggaagtgg tgactttccc agttcgtgtg atgaaagttc ttggatgtga
     9961 aggtgttatt gtaaccaatg cagctggcgg tatcggattt ggtcctggta ccttgatggc
    10021 tatctcagac catatcaaca tgacggggca aaatccattg atgggtgaaa acttggatga
    10081 ctttggccca cgtttcccag atatgtctag ggcctacaca ccagaatacc gtgccactgc
    10141 ccatgaagtg gctaaaaaac ttaatatcaa gcttgatgaa ggtgtctata tcggagttac
    10201 tggtccgact tatgaaacac cagcagaaat tcgttcctat aagacactgg gagcagatgc
    10261 agttggtatg tctacggttc ctgaagttat cgtggcagcc cactctggct tgaaagttct
    10321 gggaatttca tgtatcacta actttgcggc cggtttccaa gaagaactca atcacgaaga
    10381 agttgtagaa gtgactgaac gtgttaaagg tgatttcaaa ggcttgctta aagcgattct
    10441 tgctgaattg taagaaaaaa gatttaaaag ggggagtgcc tctgtttttt caggattgac
    10501 tgcctatccg gattaaagaa gaaacagagg aatactatga gcttcttcct gctcttataa
    10561 ctgaaagaag cggaagaata ggtatgtctg atctgatagc cagcattgtg aaagacaaga
    10621 ttctaggata ctagcattag cttcctagcc aagcagacta gtatgataag gagagatgag
    10681 aatgaattga ctttctgaat ttctcagtct tatcatatat agcacaatga gatttcgctt
    10741 gagtctgctt gtaaataaac gaaaagaaag ataagaaata atgaaaattg gtcaacgaat
    10801 tatgcgcttt ggcataaaaa attaagtatc ggagttgtat ctgttgtagt cggctttgat
    10861 ttctagctcc agctggaatt tcagccaatg aagtaaagca agatgtaaca tctgaagtgg
    10921 taataggtgt gctagattct aaggaggaat tgaaagagtc agaaaatgat gctccaaaac
    10981 tagaaactcc tcttagagag gagccaagac tagctcctca aacgcttccg gaagcaagtg
    11041 aagttcttga aaacaaaagg gaagagtcaa aagtagagat aacataacca gctcaagcgg
    11101 atgatatccg caaggttgtt ggggaattag ccaaggatat aagtattact aagttgtata
    11161 tgacaggtca ttctcttgga tgttacctag ctcagattgc agcggttgaa gcttaccaaa
    11221 aatatcctga tttttataac catgtattga ggaaagtgac aactttcagt gctcctaaag
    11281 tgattacttc cagaactgtt tggaatgcta agaatggttt ctgggatgtt ggtttggaaa
    11341 gtcgtaaatt agctgttagt ggaaaaatta agcattatgt ggttgataat gacaatgttg
    11401 tgactccctt gattcataat aatcgtgata ttgttacatt tacaggtaat tcacgcttta
    11461 aacaccgttc tcgtggctat tttgaaagtc caatgaatga tattcctaac tttaatattg
    11521 gtaaacaagc taccttggat aaacatggtt atcgtgatcc gaaattggat aaagtgcgat
    11581 tctttaagaa acaggctctg cctcgatctt ctagtcaacc aagcgctgaa ccaatggaaa
    11641 atattgcctt aggaaaacag gttactcaaa gttcgacagc tttcggagga gatgctagaa
    11701 gagctgtgga tggcaaagtc gatggtaact atggtcacaa ttctgtcact catacaaact
    11761 tccaatctaa gccttggtgg caagtagatt tggctaaaga agaaaccatt cgccaaatca
    11821 atatttacaa ccgaacagac actgcccagg atagattggc aaactttgat gtcattcttt
    11881 tagacagttc tggtaaagaa attgagtgaa aacgtataat atctcctaaa gatgtgtcag
    11941 cacaaattac gattaaccat aaaaaagcgc gctatgttcg gattgagcta gaaggctata
    12001 atgccctcag tcttgcagaa gttgaagttt tccgctttat agctacgaat gctgaaacgg
    12061 cgacacaagt ttctaagcca gttcaaccaa tcagtcagac tcctgtgaaa gataaaacat
    12121 tgacaattca acacagtgga gcttacattg cccgctactc cataacttgg gaagaagttc
    12181 cagtagataa agatggaaac caagttgttc gtagtcattc ttgggaagga aacggtcgca
    12241 accagactgc gggttttgtc ctcaacctcc caatcaaaga aaatatgaga aatctgcgag
    12301 ttaagattga gaaaaagacg ggcctactat ggaatagatg gcaaacaatc tatgaaaaca
    12361 gaccaatttc agctcaaccc caccgtaaaa ttacccattg gggtacgaca ttgaattcca
    12421 aggtgagtga cgatgatgtc ttgtaatctg atggtacaat gacagttagt ttgtctagtt
    12481 tataagaaag tactacctga gcttgaatag aactcaggta gctctctgtg aaagaacaaa
    12541 attaatactc aatgaaaatc aaagagcaaa ctaggaaact agccgcaggt tgctcaaagc
    12601 actgctttga ggttgtagat aagactgacg aagtcagtca catatataat ccaaggcgac
    12661 gttgacgtgg tttgaagaga ttttcgaaga gtataaacag aaaggtagag cgcgtgttct
    12721 aatttgaaca cgagtagaaa acttttctaa aaacaaaaac gaaaggatgg gtaaactgta
    12781 ttcgctgaac tgaatacggg cgactctcct ctaaatcaaa attaagaaag gaattgaccc
    12841 caccctaaaa gtagtgggaa aaagatagtt ggtctagcga gcatcgctca ctgcgcccaa
    12901 ctcctatttt cccttcgctt tttgatgggt ttggtatctt tctcaatata aaataaagaa
    12961 aggtagagcg tgtgttttga tttgaacacg agcggaaaac tcggaaaata gataatctga
    13021 ctgaaaaatc aggatttctc gtcaggttcc taattttcag tcgttttctt ctcgctcttt
    13081 gtatcataaa ttatgtctat ccatattgct gctcagcagg gtgaaattgc tgataaaatt
    13141 cttcttcctg gggatcctct tcgtgctaag tttattgcgg agaatttcct tgatgatgct
    13201 gtttgtttta acgaagtgcg taacatgttt ggttacactg gtacttacaa gggtcactgt
    13261 gtatctgtca tgggaactgg gatgggaatg ccatctattt cgatttatgc gcgtgagtta
    13321 atcgtagact acggtgtgaa gaaattgatt cgtgtgggaa ctgcaggttc tttgaatgaa
    13381 gaggttcatg ttcgtgaatt agttttggcg caggcggctg caaccaactc aaacatcgtt
    13441 cgtaatgact ggccacagta cgattttcca caaattgcta gctttgattt gcttgataaa
    13501 gcctaccata tcgccaaaaa acttggtatg actactcacg ttgggaacgt tttgtcatct
    13561 gatgtctttt actcaaatta ctttgaaaag aatatcgagc ttggtaaatg gggagtcaag
    13621 gctgtggaaa tggaagcagc agctctttac tatcttgctg cccaatacca tgttgatgcg
    13681 ctagctatca tgaccatctc tgatagcttg gtcaatccag acgaagacac aactgcagaa
    13741 gaacgtcaaa ataccttcac tgatatgatg aaggttggtt tggaaacctt gattgcagaa
    13801 taattatagc caaaaaggaa gccctttatg aattgtagga cttccttttc ttatccagaa
    13861 attgatctag ctctctctga tttcgaagaa tagtgacttt atgtgaatat tcttggcaaa
    13921 gtttttggta attttctttt tgagttttgc tacgcccatc ccaaagaatc catctgataa
    13981 actcccactc aaagcgttca gggcaatctg ccgccatact ttctctgact tttccacggt
    14041 atttaagata acgcttaaag gctctaaaga gacaggtcaa tggcgaaaaa ttgagaaaga
    14101 tgatttggtc agcttcttgc attcgttctt ggtagtagca ccaagaataa ttaccatcga
    14161 tgacccaagc tttatgcttg gtgagaaagt tttttatctc ggttaacatc cattcgcagt
    14221 cactgtcttg ccaaccaggt tgaaattgga gtgtgtccat gtgcagtttt ggaatggagt
    14281 agtagttaga taacttttct gctatagttg acttaccaga accagaatat ccgataattg
    14341 cgattttcat tttctacttt ttcctatttg gagacaaaaa aacagcctct atggactgtt
    14401 tcttatttag caagtttagc tgaaagacga gctttatcgc ggcttgcttt gtttttgtga
    14461 atcaaacctt tagtttctgc tttatcgata gctgagctag cagcacggaa aagttcttca
    14521 gatgggtttg cttcgaaagc ttttatagca gtacgcatag ctgatttttg agctgagttc
    14581 ttttcgtttt gtttaacgtt caattcagcg cgtttgatag ctgatttaat gtttgccaat
    14641 gttcttacct ccatatttac taactatacc attatatatg aaaacttacg ttttgacaag
    14701 ggaaaattac ttttttaagt aaatttcatc gatttcatgg ttcttgcttt tatgaagaat
    14761 cacttctgca cgatttctgg ttggttcaat ataattttgc agatttgtga gattgatact
    14821 gatccagacc tgatgggcaa aggactccac ttccccaatc ggcatctgag taaaacgata
    14881 atagtagcta tcagggtcgt tttgggctag gctcagcatt ttcaagaaac ggtccagata
    14941 ccaactttca atatcatcca ctccagcatc tacatagatg gaaaagtcaa agaagtcagt
    15001 gatatagaga cgatcgtttt gtggattttg aaagacatta a
//
LOCUS       DAVBBO010000051        14799 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ST1
            SAMEA2066453-rid20184263.denovo.051, whole genome shotgun sequence.
ACCESSION   DAVBBO010000051 DAVBBO010000000
VERSION     DAVBBO010000051.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2066453
            Sequence Read Archive: ERR351777
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 14799)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14799)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980402.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980402.1
            Genome Coverage       :: 176x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:17:33
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,141
            CDSs (total)                      :: 2,104
            Genes (coding)                    :: 1,953
            CDSs (with protein)               :: 1,953
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 16S)
            partial rRNAs                     :: 1 (23S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 151
            CDSs (without protein)            :: 151
            Pseudo Genes (ambiguous residues) :: 0 of 151
            Pseudo Genes (frameshifted)       :: 73 of 151
            Pseudo Genes (incomplete)         :: 76 of 151
            Pseudo Genes (internal stop)      :: 40 of 151
            Pseudo Genes (multiple problems)  :: 32 of 151
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14799
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2066453-rid20184263.denovo.051"
                     /strain="ST1"
                     /db_xref="taxon:1313"
     gene            <1..662
                     /locus_tag="VQU30_001665"
     CDS             <1..662
                     /locus_tag="VQU30_001665"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000526318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2447737.1"
                     /translation="IIRKVQEPEFWKEVNLSDLEKIRLAIRDLLQFLDKTDRKPYYVN
                     FEDRILSTVHETTAFLQVNDLRSYNEKVEHYLKTHLDEESISKLYHNKKLTSDDMLAL
                     EKLLWEKLGSKADYQSHYENKAIPRLVREIIGLDRESANRIFSKFLSDENLNARQISF
                     VKLIVDYIVENGFLETKVLTQEPFKSYGSVQLLFQHQLPVLRNIVQIIELINNRAGEA
                     A"
     gene            complement(1062..2408)
                     /locus_tag="VQU30_001666"
                     /pseudo
     CDS             complement(1062..2408)
                     /locus_tag="VQU30_001666"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001808790.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS1380-like element ISSpn5 family transposase"
     gene            2470..2664
                     /locus_tag="VQU30_001667"
     CDS             2470..2664
                     /locus_tag="VQU30_001667"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2447738.1"
                     /translation="MSSKKHPLGEKRNHTGSKLRQGFWMVFRLGVNNWGFKEIENKKP
                     SKNSIAGENEIILNENQRAN"
     gene            2642..2842
                     /locus_tag="VQU30_001668"
     CDS             2642..2842
                     /locus_tag="VQU30_001668"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2447739.1"
                     /translation="MKIKEQTRKLAAGCSKHCFEVVDKTDEVSSKHGFEVVDETDEVS
                     NHTYGKATLTRIEEIFEEYKSS"
     gene            complement(2922..3367)
                     /locus_tag="VQU30_001669"
                     /pseudo
     CDS             complement(2922..3367)
                     /locus_tag="VQU30_001669"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000547411.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing N-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            3375..3518
                     /locus_tag="VQU30_001670"
     CDS             3375..3518
                     /locus_tag="VQU30_001670"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000840765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2447740.1"
                     /translation="MAERFWENLSIILADRNISWIELTRKMFAGEFHYPSELNRLYQK
                     IRH"
     gene            3611..4198
                     /locus_tag="VQU30_001671"
     CDS             3611..4198
                     /locus_tag="VQU30_001671"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000821297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HET2447741.1"
                     /translation="MKRIIPVYIFQQVNVLLVSLYLLKFLCSDELTILQILYGASLIS
                     FLWMYGQRKQVIKVNMKTRIQWLGIGFVSLLIISLCFSLIHAQESTNQANLIGLQHQI
                     PWFSFLLFLINASMVEEFLYREILWNLVRKLDIRVALTSVLFALAHHPGTIIAWCLYV
                     SLGMFLGLVRYKLDLWGSMGLHLVWNLLVYSLLLF"
     gene            4597..5406
                     /locus_tag="VQU30_001672"
     CDS             4597..5406
                     /locus_tag="VQU30_001672"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000926538.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HET2447742.1"
                     /translation="MLLQKELIPMIEANLPNMAYAEKDIAKFFLKQQPLNNYSCKALC
                     ECLNVSKATLTRFAKKCGFKGFRQFIFKYQEMIREKEKLALYTEATEKVLSDYEEMLR
                     KTYTVLDEVQLERIAEMIETAERVYLYGKVSSVLALQEMKMRFMRLGVIGEVLSDEDM
                     ILWNSLLLNENCLVIGASVSGQTDIVLEGLQKAADKGAKTVLMTTRKFDEEDCFFDEL
                     LLLASTNHLSYGNRISPQFPILLITDCLFSHYLESPERQYYYNQTIIHKEE"
     gene            5411..6112
                     /locus_tag="VQU30_001673"
     CDS             5411..6112
                     /locus_tag="VQU30_001673"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000078476.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmannosamine-6-phosphate 2-epimerase"
                     /protein_id="HET2447743.1"
                     /translation="MSQIWTKEKFISQVHGGVIVSCQALPGEPLYNEEFSLMPFMAKA
                     ALEAGAVGIRANSVRDIKAIQKVVDLPIIGIIKRDYPPQEPYITATMKEVDELVECGT
                     TVIAFDATLRPRYDGLVINEFIKKIKEKYPNQLLMADVSNFDEGLYAFKSGVDFVGTT
                     LSGYTSTSVQSDEPDFELMKKLADFNIPVIAEGKIHYPEQLKKAYSLGVTSVVIGGAI
                     TRPKEIAQRFINVIK"
     gene            6137..7054
                     /locus_tag="VQU30_001674"
     CDS             6137..7054
                     /locus_tag="VQU30_001674"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002894436.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylneuraminate lyase"
                     /protein_id="HET2447744.1"
                     /translation="MKDLTKYKGVIPAFYACYDENGEISQERVKSLVQYFIDKGVKGI
                     YVNGSSGECIYQSVEDRKQIIEAVMEVAKGKLTVINHVACNNTKDSIELAKHSESVGV
                     DAIAAIPPIYFKLPEYSIAAYWNAMSEAAPNTDFIIYNIPQLAGVALTGSLYATMRQN
                     PRVIGVKNSSMPVQDIQMFVAAGGEDYIVFNGPDEQYLGGRLMGAEAGIGGTYGVMPD
                     LFLKLESLIQERDLDTAKKLQYAINEVIYKMISGKANMYAVAKEVLRLNEKLDLGSVR
                     QPLEALAEGDLEVAKQAAELIQQARKEFL"
     gene            7082..8623
                     /locus_tag="VQU30_001675"
     CDS             7082..8623
                     /locus_tag="VQU30_001675"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000537364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sodium:solute symporter"
                     /protein_id="HET2447745.1"
                     /translation="MGTTGFTIIDLIILIVYLLAVLVAGIYFSKKEMKGKEFFKGDGS
                     VPWYVTSVSIFATMLSPISFLGLAGNSYAGSWILWFAQLGMVVAIPLTIRFILPIFAR
                     IDIDTAYDYLDKRFNSKALRIISALLFIIYQLGRMSIIMYLPSAGLSVLTGIDINILI
                     ILMGAVAIVYSYTGGLKSVLWTDFIQGVILISGVVLALFVLMANIKGGFGAVAETLAN
                     GKFLAANEKLFDPNLLSNSIFLIVMGSGFTILSSYASSQDLVQRFTTTQNIKKLNKML
                     FTNGVLSLATATVFYLIGTGLYVFYQVQNAGSAASNIPQDQIFMYFIAYQLPVGITGL
                     ILAAIYAASQSTISTGLNSVATSWTLDIQDVISKNMSDDRRTKIAQFVSLAVGLFSIG
                     VSIVMAHSDIKSAYEWFNSFMGLVLGLLGGVFILGFVSKKANKQGAYAALIVSTIVMV
                     FIKYFLPPTAVSYWAYSLISISVSVVSGYIVSVLTGNKVSAPKYTTIHDIPEIKADSS
                     WEVRH"
     gene            8642..9100
                     /locus_tag="VQU30_001676"
     CDS             8642..9100
                     /locus_tag="VQU30_001676"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000587138.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhcH/YjgK/YiaL family protein"
                     /protein_id="HET2447746.1"
                     /translation="MIISEQSDFRRYASINKHFSKVCDFLENTNLTDLVDGKVDIDGE
                     NVFANCMIYLADGVPGDIFETHKKYLDIHIVVENTEKMAVTSPVRAQSRVPFSEEKDI
                     AFYDSKDYQIVELLPGNMLVTFEEDLHQPKIHCNDEPVKKLVIKVLNEEK"
     gene            9102..11324
                     /locus_tag="VQU30_001677"
     CDS             9102..11324
                     /locus_tag="VQU30_001677"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000739354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exo-alpha-sialidase"
                     /protein_id="HET2447747.1"
                     /translation="MKKNIKQYVTLGTAVVLSAFVANSVAAQETETSEVSTPELVQPV
                     APTTPISEVQPKSGNSSEVTVQPRTVETTVKDPSSATEETPVLEKNNVTLTGGGENVT
                     NELKDKFTSGDFTVVIKYNQSSEKGLQALFGISNSKPGQQNSYVDVFLRDNGELGMEA
                     RDTSSNKNHLVSRPASVWGKYKQEAVTNTVAVVADSVKKTYSLYANGTKVVEKKVDNF
                     LNIKDIKGIDYYMLGGVKRAGKTAFGFNGTLENIKFFNSALDEETVKKMTTNAVTGHL
                     IYTANDTTGSNYFRIPVLYTFSNGRVFSSIDARYGGTHDFLNKINIATSYSDDNGKTW
                     TKPKLTLAFDDFAPVPLEWPRDVGGRDLQISGGATYIDSVIVEKNNKQVLMFADVMPA
                     GVSFREATRKDSGYKQIDGNYYLKLKKQGDTDYNYTIRENGTVYDDRTNRPTEFSVDK
                     NFGIKQNGNYLTVEQYSVSFKNNKKTEYRNGTHVHMNIFYKDALFKVVPTNYIAYISS
                     NDHGESWSAPTLLPPIMGLNRNAPYLGPGRGIIESSTGRILIPSYTGKESAFIYSDDN
                     GASWKVKVVPLPSSWSAEAQFVELSPGVIQAYMRTNNGKIAYLTSTDAGTTWSAPEYL
                     KFVSNPSYGTQLSIINYSQLIDGKKAVILSTPNSTNGRKHGQIWIGLINDDNTIDWRY
                     HHDVDYSNYGYSYSTLTELPNHEIGLMFEKFDSWSRNELHMKNVVPYITFKIEDLKKN
                     "
     gene            11364..12473
                     /locus_tag="VQU30_001678"
     CDS             11364..12473
                     /locus_tag="VQU30_001678"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000248711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HET2447748.1"
                     /translation="MVNYGIVGAGYFGADLARSMNKIEDAKVVAVFDPNHGEEVAQEL
                     GSDVCASLDELVAREDIDCVIVASPSYLHREPVVKAAQHGKHVFCEKPIALSYEDCKA
                     MVDACKENNVIFMAGHIMNFFNGVHHAKELITQGKIGKVLYCHAARTGWEEQQPTVSW
                     KKLRSQSGGHLYHHIHELDCIQFIMGGLPEKATMVGGNVYHKGENFGDEDDMLIVNLE
                     YSDDRYAVLEYGNAFRWGEHYVLIQGTEGAIKLDLFNTGGTLRVKGEGESHFLVHETQ
                     EEDDDRTAIYTGRGMDGAIAYGKPGVRCPLWLQTCIDKEMEYLHDIIKGGEITEEYEK
                     LLNGVAALESIATADACTLSVKEDRKVSLSEITNA"
     gene            12630..13520
                     /locus_tag="VQU30_001679"
     CDS             12630..13520
                     /locus_tag="VQU30_001679"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000691258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HET2447749.1"
                     /translation="MKIIGIDIGGTTIKADLYNEFGTSLNQFKEIETIIDYDLGTNQI
                     LNQVCDLIGEYILNHSIDGVGISTAGVVNANTGEIIYTGYTIPGYIGVNFTFEIEKRF
                     GLSTFVENDVNCAALGELWKGQAKDKKNVVMVTIGTGIGGSIIVNGQIVNGFNYTAGE
                     VGYIPVGNSDWQSKASTTALIHLYQKKSLKTNQTGRTFFTDLRAGDKVAKETFEIFVE
                     NLTKGLLTITYLLNPEILILGGGILAKKDILLPEIQSSLAKNAMDNRFLPKNLVAATL
                     GNEAGRIGAVKNFLDRISNK"
     gene            13545..13868
                     /locus_tag="VQU30_001680"
     CDS             13545..13868
                     /locus_tag="VQU30_001680"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000185366.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2447750.1"
                     /translation="MTNSVFSTMQDIENVATDIIKSYDNEIYTYKAVSQEELEKLEKS
                     YDEKSHEELVSIESNLEMKQQNLIDEVNKTIKENYEKIQYISSSRRGEFVEKIIGRVV
                     EKYGY"
     gene            13858..>14799
                     /locus_tag="VQU30_001681"
     CDS             13858..>14799
                     /locus_tag="VQU30_001681"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001018351.1"
                     /note="Produces ATP from ADP in the presence of a proton
                     gradient across the membrane. Subunit I is part of the
                     membrane proton channel; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit I"
                     /protein_id="HET2447751.1"
                     /translation="MAISQMKRISLLFSKSSLDDVLKTIQELESVQFRDLKVQDNWSE
                     ALEKDEVVFPTIQISHTSNSNHGVIEGNDALIYLMNQQQYLEATVEKLQEYLPKENTF
                     KLLQQPPITTSYEELEKFGKANVAEGVLKKVNRQINRVHELERHIQSNNEEIERLIKW
                     EKLEIIPAHLEQFFFCKGKVGTIPRTVDNRLYNSFLENNIEVQEIFSNDREYGVVVFY
                     QSSCSIDFDEYLFEPFDYSRKELPKQRVVDLDQENMQLITEKENIIASLQDSKNNLID
                     LQWQIDYILSIYARQISKNNLLSTPHLVALEGWIEETR"
BASE COUNT         4961 a         2254 c         2929 g         4655 t
ORIGIN      
        1 aaattatcag gaaagtacag gagcctgaat tttggaaaga agttaacttg tctgatttgg
       61 aaaaaattcg tcttgctatt cgagatttat tacagttttt ggataaaaca gaccgtaaac
      121 cctactatgt taactttgaa gatcgtatac tctccactgt tcacgagacc acagcatttt
      181 tgcaggtcaa cgatcttcgg tcttacaatg aaaaagttga gcattatttg aaaactcatc
      241 tggatgagga gtccatttct aagctatacc ataataaaaa gttgacatct gatgatatgc
      301 ttgcacttga aaaattgctt tgggaaaaat taggtagtaa agcagactac caaagtcatt
      361 atgaaaataa ggcaattccg agattggttc gtgagattat tggcttagat agagagtctg
      421 ccaatcgtat tttctctaaa tttttgtcgg atgagaatct taatgccagg cagatttcat
      481 ttgtaaaatt gattgtagac tacattgtag aaaatggttt tttagagacg aaagtgttaa
      541 cgcaagagcc gtttaaatct tatggttctg ttcaactact cttccaacac caactaccag
      601 tacttcgtaa tattgttcaa atcattgaac ttatcaataa tcgagctgga gaagcggctt
      661 aaattctaaa gtgattgcca tgctgagact catttaaaat taaaaagagt agaaatttat
      721 gctatatatg agaagtttta ttaggaagaa tgtcatcgtt ttcctagaat acagtatcag
      781 ttgttaagtg gttgataaat ttcaaagtag atacttgtac cacgatgttt gttgatcgag
      841 ttattaacaa aagagctact ttgattttaa cccaaatcat tcatacctct ctcaactaga
      901 tgtaacttac aaaacccctg acctcatgag ccactttctt cctcctcatg aggtcagttt
      961 tactttctgc tgttccagta tcgtttttcc tcgctagatt tcctcaaaag ggcagactcc
     1021 tcccttggtg cgtcacacga ttttttcatc tcgactgttc tttaatgcat cattaacgac
     1081 gcttttcttc caggtggttc ataaggaaca ggaagattca ggttgacttt tctaatccta
     1141 gaataaagtg ctgaaaacaa ttcggaatag gcatagagac tagacaattt gaggagctgc
     1201 ttgcgtcctg ttcgaacaca ttttcctacc acgtgaagaa aaagatggcg gaagcgtttg
     1261 attgttaaag tttggaagtc acctccagct agatgtttga gaaaaagata gagattgtag
     1321 gcgatacagc tcatcatcat acgaacttcg tttttgatta aggttgaact atccgtttta
     1381 tcgccaaaaa atccctcctt catctccttg atgaaattct cggattgacc acgtccacga
     1441 taaagctgaa actggtcttg gcttgttcca ctcgtcatat ttgtaacgag agaaataaca
     1501 tcgtagaaca agtttccttc ttttcgttca gagaactggc agacacgacg cttgtgcgac
     1561 caagatcctg cttgatagag agtttctgag taggcggagt ggggcaagat ggttaagtcc
     1621 tcatcctgtg ggcaagggag ggaaaggtct ccaagacggc tcagaacagt atttttcttg
     1681 agttttatga gttagtattg ccctgttttt tcaattaaat cgtataattt gggggtcgca
     1741 aagccactat ccattcgaaa gagaagttga ttaaaccgtt ctaaaacagg tgtgataaag
     1801 ctgtctgcct cttcagaaca ataacgatta ccaggacgaa gctgggcatt gaaacaataa
     1861 cctgtcttcc cctcgaaagc ataaagagga tgatagccat gagcacgata gtgggcgtta
     1921 taagcaacac cttcttgctt gccataagtt gtgaaatggg tagaatcgat atctacaatg
     1981 agttggttta gctggtgaaa ctgtaaaaag aattcgacca attcaaggtt gaggcatcgc
     2041 aaactatgga ctgtttcctc gtcagttctg gaaagaaaac gggataaggt tggctgtgaa
     2101 gcaagctgcc ctccttccaa caattttgga aagtaggcat cagctgacaa ttctttacaa
     2161 gcatagtccg ttccatagcc tgttaacagt tgaaagagga actggacaag gatatctgaa
     2221 tccgaataac gacagtagcg gcgttggtca ttcgttacta aatacttaga aatccgctct
     2281 tttagtttca actgggaaaa aagttcctga aaaaagataa gaccaccata ctgggttaaa
     2341 tgacctccat cgaaagatag ttggtaaaaa gacttgtttt ggaagtgatg atttggtaaa
     2401 ctgttcatgt gagtttcctt tctttttgtg tttttttcta cacttatacc ataaagggga
     2461 aattcttttt tgtctagtaa aaaacaccca ttgggtgaaa aaagaaacca tacaggatct
     2521 aagctaaggc aaggattctg gatggttttt agattagggg tgaataattg gggttttaaa
     2581 gaaatagaaa acaaaaagcc gagcaagaat tcaattgcag gagaaaatga aataatactc
     2641 aatgaaaatc aaagagcaaa ctaggaaact agctgcaggc tgctcaaaac actgttttga
     2701 ggttgtagat aagactgacg aagtcagctc aaaacatggt tttgaggttg tagatgaaac
     2761 tgacgaagtc agtaaccata cctacggcaa ggcgacgttg acgcggattg aagagatttt
     2821 cgaagagtat aaatcttcct aggataaagc aaagagcctg ggacaaaata gttctcgacc
     2881 acaaaaaagc tagagatttc caattgtgga actttagctt tttaattttg agtcgttctc
     2941 ttattgtatt ttaggaggtt attggccata agtaccaatc ccatgtcaat tctcacttga
     3001 cgcttgcccc tcagattaca tctcttgtaa cccaaacaag cctttatctg cccaaagaca
     3061 ggtgacattc tttagctttc aagttttgat agccttcgtt catatacagt cccttttgag
     3121 gggctgattc aggttcgtcg gcgtagtaaa ccttgatttc ttgtttaaag tctgtctgtg
     3181 ttttctgatg tttggtatgg tgaaaacgat aataccagcc atcaggatgt gtatagctat
     3241 cctccttgtc attatagtac caattcgcta agtttctagc tgactgttta tagcctctct
     3301 tctgttcctt atcaaacatg gcatatttaa tcagatggtt tacctccttt tcatctaact
     3361 aaaggagaag caatatggct gaacgatttt gggagaactt gtccattatt ttggctgaca
     3421 gaaatatcag ctggattgag ttaaccagaa aaatgtttgc gggagagttt cactatccaa
     3481 gtgaattgaa tcgtttgtat caaaagattc gccactagaa gatggaacaa cgaatgcctc
     3541 aaagtccatg ggtagaaagg attgtgcagg tattagattt agattatgaa gatttatttc
     3601 ggaggtaatt atgaaaagaa taattccagt ttatatattc caacaagtaa atgtcctatt
     3661 ggtatctcta tacttattga aatttctttg tagcgatgag ttaactatac tacagattct
     3721 ctatggagcg tcactcattt cttttttatg gatgtatggt caacgaaaac aagtgatcaa
     3781 ggttaatatg aaaactagga tacaatggct tggtattgga ttcgttagcc tactgattat
     3841 aagtctatgt tttagtctaa tccatgcgca agaaagcacg aatcaagcaa acttaattgg
     3901 acttcaacat caaattcctt ggttttcatt tttattgttt ttaatcaatg cgagtatggt
     3961 tgaagaattt ctgtatagag aaattttatg gaacttggtt agaaaattag atattcgagt
     4021 tgctttgaca agtgttttat ttgccttagc acatcatcca ggaaccatta tagcttggtg
     4081 tttgtatgta tcgctgggga tgtttttagg gcttgtacgc tacaaattgg acttatgggg
     4141 cagtatgggg ctacatttgg tgtggaacct actagtttat agtttgctgc ttttttaaaa
     4201 taagtgatct gatttatctc ataaatcagt agtttttata ggattatttt taattcggaa
     4261 acaaaaatgt attaacagca taaaataaag aaactaggaa catttttttt attttttaga
     4321 aataaaatgt tgtatagaaa ttccgaaaga aataataaaa tcaaaataaa aattaataaa
     4381 ataggtatat ttgaacatat tgacgtcgac aaatgttctt gcaagacata aaatacaaat
     4441 aaaaagaata aaaaattttt atatttttat atttgttgtt ctgttataaa atgaaagaaa
     4501 ttagaaacta gtttctaaat catgaaaaat attgaaaaaa aaaaaataag tgttaaaata
     4561 aagaatgtaa acgtttactt caataaagga gctcatatgt tactgcaaaa agaactaatt
     4621 ccaatgatag aagctaactt accaaatatg gcatatgctg aaaaagacat tgctaaattc
     4681 ttcttaaaac agcaacctct gaataattat tcatgtaagg cattgtgcga atgccttaat
     4741 gtatccaaag caacattgac tcgatttgcg aaaaaatgtg gttttaaagg ttttagacaa
     4801 ttcattttca aataccaaga gatgattcgt gagaaagaaa agttagcatt gtatacagag
     4861 gctacagaaa aagttttatc cgactatgaa gaaatgttga gaaaaactta cacggttctt
     4921 gatgaagttc aacttgagcg tattgctgag atgatagaaa ctgctgagcg tgtatatctt
     4981 tatggtaaag taagttctgt tcttgcttta caagaaatga agatgagatt tatgcgtctc
     5041 ggagtcattg gtgaagtatt atcagacgag gatatgattt tgtggaatag cttattactt
     5101 aatgaaaatt gccttgtcat tggagcatcc gtttcaggtc aaactgatat tgtactagaa
     5161 ggtcttcaaa aagctgcgga taaaggcgct aaaacagttt taatgactac aagaaaattt
     5221 gacgaagaag attgtttctt tgatgaacta ttgttattag cttcgaccaa tcatctctcg
     5281 tatggcaatc gcatatcacc tcagtttcca atacttttaa ttacagactg cttattctct
     5341 cattatctgg aaagtccaga gagacaatat tattacaatc aaactattat ccataaggag
     5401 gaataataaa atgagtcaaa tttggactaa agaaaaattt ataagtcaag tccatggtgg
     5461 agtcattgtt tcttgtcaag ctttacccgg tgaacccctt tataatgaag aatttagctt
     5521 gatgcctttt atggctaaag cagctttaga ggcaggagca gtgggcattc gcgcaaattc
     5581 tgtgcgtgat attaaagcaa ttcagaaagt agtagattta ccaataattg gaattatcaa
     5641 aagagattat ccacctcaag aaccatatat tactgctacg atgaaagaag tagatgaact
     5701 tgtagaatgc ggaacaacag tcattgcatt tgatgcaact ttaagaccaa gatatgatgg
     5761 cttagttatc aatgaattta tcaaaaaaat aaaagaaaaa tatcctaatc aattgttgat
     5821 ggcggatgta agtaattttg atgaaggtct ctatgcattt aaatcaggcg ttgattttgt
     5881 tggtacaaca ttatcagggt acacaagtac aagtgtacaa tcagatgagc ctgattttga
     5941 actaatgaaa aaattggctg attttaatat tccggtaatt gccgaaggaa aaattcatta
     6001 tccagaacaa ttaaaaaaag cttatagttt aggtgttacc agtgttgtca ttggtggagc
     6061 gattacacgt ccaaaagaaa ttgctcagcg atttattaat gtcatcaaat aaaaaacaat
     6121 ataaaggaga aatctgatga aagatttaac taaatacaaa ggcgttattc ctgcatttta
     6181 tgcttgctat gatgaaaatg gtgaaattag ccaagaacgt gtaaaatctc tggtgcaata
     6241 tttcattgac aaaggtgtaa aaggtatcta tgtaaatggt tcttcaggtg aatgtattta
     6301 ccaaagtgta gaagatcgta aacaaattat tgaagctgtt atggaagttg ctaaaggtaa
     6361 attaacagtt atcaaccatg ttgcatgtaa taacacgaaa gatagtattg aattggcaaa
     6421 acattcagaa agtgttggag tcgatgctat tgctgctatc ccacctattt acttcaaatt
     6481 gccagaatat tcaattgcag catattggaa tgcaatgagt gaagctgcgc caaatacaga
     6541 ttttatcatt tataatattc cacaattggc aggggttgcg ttgactggta gtttgtatgc
     6601 aacaatgcgt caaaatcctc gtgtgattgg agttaaaaat tcttctatgc ctgtacaaga
     6661 tattcaaatg tttgtagctg caggtggaga agattacatt gtattcaatg gtccagatga
     6721 acaatatctt ggtggtcgct tgatgggagc agaagctggt attggtggta cttatggcgt
     6781 tatgccagat ttgttcttga aattggaaag tttgattcaa gaacgagatt tagatactgc
     6841 taaaaaactt caatatgcta tcaatgaagt tatctataag atgatatcag gtaaggcaaa
     6901 tatgtatgct gtagcaaaag aggttttgcg tctaaatgaa aaacttgatt taggttctgt
     6961 tcgtcaaccc ttagaagcat tggcagaagg tgacttggaa gttgcaaaac aagcagcaga
     7021 acttattcaa caagcacgaa aagaattttt ataataaata aaatcaatat ggagatatgt
     7081 tatgggcaca acaggattta caataattga cttaattatc ttgattgttt atttacttgc
     7141 ggtgttggtt gcaggtatct atttctctaa aaaagagatg aaaggaaaag agttcttcaa
     7201 aggagatggt tcggttcctt ggtatgttac ttcggtatcc atttttgcca caatgctcag
     7261 tccgatttcc ttcttgggac tcgctggtaa ctcttatgca ggtagctgga ttttatggtt
     7321 tgctcaatta gggatggtag tagctattcc actgacaatt cgttttatct tacctatctt
     7381 tgcacggata gacatcgata cggcatatga ttacttggat aaacgtttta attctaaagc
     7441 acttcgtatt atttcagcac tcttgtttat tatttatcaa ttgggacgta tgtctatcat
     7501 tatgtacctc ccatcagctg gtttatcagt attgacagga attgacatca atattttgat
     7561 tattttgatg ggtgcagttg caattgttta ttcttacact ggtggtctaa aatccgtatt
     7621 atggacagac tttattcaag gtgtgattct gattagtggt gtcgttttag ctttatttgt
     7681 actgatggct aatattaaag gtggctttgg tgcagtagca gaaacattag caaacgggaa
     7741 attccttgct gcaaatgaaa aacttttcga tcctaacttg ctttcaaact ccatcttttt
     7801 aattgtgatg ggttcaggct ttacaatctt gtcttcctat gcttcatctc aagatttggt
     7861 tcaacgtttt actacaacac aaaatattaa gaaacttaat aagatgttgt tcacaaacgg
     7921 tgtcttgtca cttgcaactg caacagtctt ttacttgatt ggtacaggct tgtacgtatt
     7981 ctatcaagta caaaatgcag gtagtgcagc tagcaatatc cctcaagacc aaatctttat
     8041 gtactttatt gcataccagt taccagtagg tatcacaggt ttgattttgg cagcgattta
     8101 tgcagcatct caatcaacta tttcaacagg tttgaactct gttgcaactt catggacatt
     8161 ggatattcaa gatgtcattt ctaaaaatat gtcagacgat cgtcgtacga aaattgcaca
     8221 attcgtatct ctagcagtag gtttattctc aattggtgtt tccattgtca tggctcactc
     8281 agatattaaa tctgcatacg aatggttcaa tagcttcatg ggacttgtac ttggtctact
     8341 tggtggtgta tttattcttg gatttgtttc taaaaaagca aataaacaag gtgcttatgc
     8401 agcgctgatt gtatcaacta tcgtcatggt atttattaaa tacttccttc ctccaacagc
     8461 tgtgagctac tgggcatatt cattgatttc aatctctgta tcagtagttt caggttatat
     8521 tgtatctgtt cttactggaa ataaagtatc tgcacctaaa tatacaacga ttcatgatat
     8581 tccagaaatt aaagcggatt caagttggga agttcgtcac taatagaaaa gagaaaataa
     8641 tatgattatt tctgaacaat ctgattttag acgatatgct tctatcaata aacatttttc
     8701 aaaagtctgt gattttttag aaaatacaaa tttgacagat ttagttgatg gaaaagttga
     8761 tattgacggg gaaaatgttt ttgcaaattg tatgatctat ctagctgatg gagtcccagg
     8821 agatattttt gaaactcata agaaatattt agatattcat attgttgttg aaaatactga
     8881 aaaaatggca gtaacttccc cagttcgtgc ccagtcacgt gtacctttta gcgaagaaaa
     8941 ggatattgct ttttacgata gcaaagacta tcaaattgtt gaattgcttc cagggaatat
     9001 gttggtgact tttgaagaag atcttcacca accaaagatt cattgcaatg atgagcctgt
     9061 taaaaaactt gttattaaag ttttaaacga ggaaaaataa aatgaaaaaa aatattaaac
     9121 aatacgtaac cttaggtact gcagtggtat tatcagcatt tgttgctaac tcagttgcag
     9181 ctcaggagac tgaaacttct gaagtatcaa caccagagtt ggtgcaacct gttgcaccaa
     9241 cgactccgat ttcggaagta caacctaaat cgggtaactc ttcggaagtt actgtacaac
     9301 ctagaacagt cgaaactact gttaaggatc catcttctgc aacggaagaa actcctgtct
     9361 tagaaaaaaa taatgttact ttaacagggg gcggagaaaa tgttactaat gagttaaagg
     9421 ataaatttac tagcggtgac tttactgtag tgattaagta caatcagtct agtgagaaag
     9481 gcttacaagc tctgtttgga atatctaatt ctaaacccgg tcaacaaaat agttatgtag
     9541 atgtgttcct tagagacaat ggtgaattgg gaatggaagc gcgtgatact tcttccaata
     9601 aaaatcacct agtatccaga cctgcttcag tttggggtaa gtacaaacaa gaagctgtga
     9661 ctaacactgt tgcagtagta gcagattcag tcaaaaaaac atattcttta tatgcaaatg
     9721 gtacaaaagt agtagaaaag aaagtggata acttcttaaa catcaaggat attaaaggta
     9781 ttgattacta tatgcttggg ggagtgaaac gtgcaggaaa aacggcgttt ggttttaacg
     9841 gaacactaga aaatatcaaa ttctttaata gtgcattgga tgaagaaact gttaaaaaga
     9901 tgacaacaaa cgctgttact ggacatttaa tttatacggc taatgataca acaggttcta
     9961 actatttccg tattccagtt ctgtatactt ttagcaatgg tcgggtattt tcaagcattg
    10021 acgctcgtta cggcggaact catgattttt tgaataaaat taatattgct acaagttata
    10081 gtgatgataa tggtaagaca tggactaaac caaaattaac attggcattc gatgattttg
    10141 cgccagtacc attagaatgg cctcgtgatg ttggtggacg tgacttacaa atcagcggtg
    10201 gtgcaaccta tattgactct gttattgttg aaaaaaataa caaacaagta ctcatgtttg
    10261 cggatgtgat gcctgctgga gtaagtttta gagaagctac tagaaaagat tcaggttata
    10321 aacaaattga tggtaattat taccttaaat taaagaaaca aggtgatact gattacaatt
    10381 atactattcg tgagaatggt actgtatacg acgatcgtac caacagacca actgaatttt
    10441 cagtagataa aaatttcggt attaaacaaa atggtaatta tttgacagta gagcaatatt
    10501 cggtttcatt taaaaataat aaaaagactg aatatcgtaa tgggactcac gtccatatga
    10561 atatcttcta caaagatgca ttgttcaaag tagtgccaac gaactatatt gcatatattt
    10621 ctagcaatga tcatggcgaa tcttggtctg caccaacttt attacctcct ataatgggac
    10681 ttaatcggaa tgcgccttat ttgggtcctg gacgtggaat cattgaaagc tcaactggac
    10741 gtattcttat tccgtcttac actggtaaag agtctgcatt catttatagt gacgataatg
    10801 gagcatcttg gaaagttaaa gttgtgccac ttccttctag ttggtcagca gaagcacaat
    10861 ttgtagaatt gagtccagga gtaattcaag catacatgcg tacaaataat ggtaaaattg
    10921 catatttaac aagtacagac gcaggtacta cttggagtgc accggaatat ttgaaatttg
    10981 tttcaaatcc aagttatgga acacaattat caatcatcaa ttatagtcaa ctgattgatg
    11041 gtaaaaaggc tgtcatttta agtactccaa actccacaaa tggtcgtaaa cacggacaaa
    11101 tttggattgg tctaattaat gatgataata caattgattg gcgttatcat cacgacgttg
    11161 attatagtaa ctatggatac tcatattcaa cattgacaga gttaccaaat catgaaattg
    11221 gattgatgtt tgaaaaattt gattcatggt ctcgtaatga acttcatatg aaaaatgttg
    11281 taccatatat aacatttaag attgaagatc tgaaaaagaa ttaaagctga aatttgaaaa
    11341 tatataaaaa gaggataaaa attatggtaa attacggtat tgttggagct ggatattttg
    11401 gagctgattt agctcgctca atgaacaaaa ttgaagatgc aaaagtggtt gcggtatttg
    11461 acccaaatca tggagaagaa gttgctcaag agttgggatc agatgtttgt gcaagtttag
    11521 atgaacttgt agcacgtgaa gatattgatt gtgtgatcgt agcttcacct agctaccttc
    11581 accgtgaacc agttgtgaaa gctgctcaac atggcaaaca cgtattttgt gaaaagccaa
    11641 ttgcattgtc ttatgaagat tgtaaagcca tggttgacgc atgtaaagaa aataatgtta
    11701 tctttatggc tggtcacatc atgaacttct ttaacggtgt acaccatgct aaagaattga
    11761 ttactcaagg taaaatcggt aaagttcttt attgccatgc cgctcgtaca ggttgggaag
    11821 aacaacaacc aactgtatca tggaagaaac ttcgttctca atctggagga catttgtacc
    11881 atcatattca tgaattagat tgcattcagt ttatcatggg aggacttcct gaaaaagcga
    11941 caatggtagg aggcaatgta tatcataaag gtgaaaactt tggtgatgaa gatgatatgc
    12001 tcattgtaaa cttagaatac tctgatgatc gttatgctgt tttggaatat ggtaatgctt
    12061 tccgttgggg tgaacactac gtcttgattc aaggaactga aggagctatc aaacttgatt
    12121 tgttcaatac tggaggtact cttcgtgtta aaggtgaagg agaatcacac ttcttagttc
    12181 atgaaactca agaggaagat gatgaccgta cagctatcta taccggtcgt ggtatggatg
    12241 gagcaattgc gtacggtaaa ccaggagtac gttgcccatt atggttgcaa acatgtattg
    12301 ataaagaaat ggaatatcta catgacatca ttaaaggtgg agaaattaca gaagaatatg
    12361 aaaaacttct caatggtgta gctgctttag aatcaatcgc taccgctgat gcatgtactt
    12421 tatcagttaa agaagatcga aaagtaagtc tttcagaaat cacaaatgct taacttttgt
    12481 aaaacagaat agtaaattct tatcattata taatttctaa agttctgtga tacaactcat
    12541 tgaataaaga aatagagatg ggactgggat aatgcccagt cccatttttt atcaaaaagt
    12601 aatgagatca aaaatgtggg agtgatgaaa tgaagattat agggatcgat attggcggaa
    12661 caacaattaa agcagattta tacaatgagt ttggaacgag tttaaatcag ttcaaagaga
    12721 tagaaacaat tattgactat gatttgggaa cgaaccagat attaaatcag gtctgtgatt
    12781 taattggtga gtatatttta aatcattcaa ttgatggtgt tgggatttcc actgctggag
    12841 ttgttaatgc taatacagga gagatcatct atacaggcta tacaatacca gggtatatcg
    12901 gagtaaactt tactttcgaa atagaaaaac gttttgggtt gtctactttt gttgaaaatg
    12961 atgttaattg tgctgcatta ggtgaattgt ggaagggaca agccaaagat aagaaaaatg
    13021 tagtaatggt tactattgga acaggtatag gaggcagtat tattgtcaat ggacaaattg
    13081 ttaacggatt taactatact gctggtgaag taggctatat tcctgtaggt aattcggatt
    13141 ggcaaagcaa agcctcaaca accgcattga ttcatttata tcaaaagaaa agcttgaaaa
    13201 ctaatcaaac tgggcgtact ttctttactg atttaagagc tggagataaa gtcgctaaag
    13261 aaacttttga aatttttgta gaaaatctaa caaaaggttt attaacgatt acttatctac
    13321 ttaatccaga aattctcata ttaggaggtg ggatcctggc taaaaaggat attttgttac
    13381 ctgaaattca aagttcttta gctaaaaatg caatggataa taggtttttg cctaaaaatc
    13441 ttgtggcagc tacattagga aatgaagctg gtcgtatagg agctgtaaaa aatttcttag
    13501 atagaatttc taataaatag tatgaaagat aaggaggtgt cacaatgact aactctgtat
    13561 tttcgacaat gcaagatatt gagaatgttg caaccgatat tataaaatca tatgataatg
    13621 agatttatac ttataaagct gtttcccaag aagaattgga aaaactagaa aaaagttatg
    13681 atgaaaaaag tcacgaagaa ttagtttcaa tagaaagcaa tttagaaatg aaacaacaga
    13741 accttattga tgaggttaat aaaacaatca aggaaaatta tgaaaagatt cagtatattt
    13801 catcaagtag gagaggagaa tttgtagaaa aaattattgg tagggtggta gaaaaatatg
    13861 gctattagtc agatgaaaag aatttctcta ctattttcta aaagtagtct tgatgatgtt
    13921 ttaaaaacta ttcaagaact agagtcagtg cagttccgtg atttaaaggt tcaggataac
    13981 tggtcagaag ctctagaaaa agatgaggtt gtatttccaa ctattcaaat ttctcatact
    14041 tctaattcca atcatggggt tattgaagga aatgatgcct tgatttattt gatgaatcaa
    14101 caacaatatt tagaagcaac tgtagagaaa ttacaagaat acctaccgaa agaaaacacg
    14161 tttaaattat tacagcaacc tccgataacg acctcttatg aagaattaga aaaatttggt
    14221 aaagctaatg ttgctgaggg tgttcttaaa aaagtgaatc gtcaaataaa cagagttcat
    14281 gaattagaaa gacacattca aagtaataat gaggaaatag agagattaat aaaatgggaa
    14341 aaattagaaa ttattcctgc gcatttagaa caattttttt tctgtaaagg aaaagtcgga
    14401 acaattccaa ggactgtaga taatcgctta tacaatagtt ttttagaaaa caatattgaa
    14461 gttcaagaaa tattttctaa tgatagagag tacggtgttg ttgttttcta tcagtccagt
    14521 tgctctattg attttgatga atacttattt gaaccatttg attattctag aaaggaatta
    14581 ccgaagcagc gagtagtaga tttggatcaa gaaaacatgc agttaataac tgaaaaagag
    14641 aatattatcg catcgttgca agattcaaag aataatttga tagatttaca atggcaaatt
    14701 gactatattt tatctatcta tgctcgtcaa atctctaaga ataacctttt gagcactccg
    14761 catctagttg cactagaagg atggatagaa gaaactcgt
//
LOCUS       DAVBBO010000052        14432 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ST1
            SAMEA2066453-rid20184263.denovo.052, whole genome shotgun sequence.
ACCESSION   DAVBBO010000052 DAVBBO010000000
VERSION     DAVBBO010000052.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2066453
            Sequence Read Archive: ERR351777
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 14432)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14432)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980402.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980402.1
            Genome Coverage       :: 176x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:17:33
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,141
            CDSs (total)                      :: 2,104
            Genes (coding)                    :: 1,953
            CDSs (with protein)               :: 1,953
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 16S)
            partial rRNAs                     :: 1 (23S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 151
            CDSs (without protein)            :: 151
            Pseudo Genes (ambiguous residues) :: 0 of 151
            Pseudo Genes (frameshifted)       :: 73 of 151
            Pseudo Genes (incomplete)         :: 76 of 151
            Pseudo Genes (internal stop)      :: 40 of 151
            Pseudo Genes (multiple problems)  :: 32 of 151
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14432
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2066453-rid20184263.denovo.052"
                     /strain="ST1"
                     /db_xref="taxon:1313"
     gene            complement(<1..2288)
                     /locus_tag="VQU30_001682"
     CDS             complement(<1..2288)
                     /locus_tag="VQU30_001682"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015898732.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="accessory Sec-dependent serine-rich glycoprotein
                     adhesin"
                     /protein_id="HET2447752.1"
                     /translation="MFKVMRGGVDTTQVMTETVEDKVSHSITGLDILKGIVAAGTVIS
                     GTVATQTKVFTNESAVLEKTVEKTDALATNDTVVLGTISTSNSASSTSLSASESASTS
                     ASESASTSASTSASTSASESASTSASTSISASSTVVGSQTAAATEATAKKVEEDRKKP
                     ASDYAASVTNVNLQSYAKRRKRSVDSIEQLLASIKAAVFSGNTIVNGAPAINASLNIA
                     KSETKVYTGTGLDSVYHVPIYYKLTVTNDGSKLTFTYTVTYVDPTTRALGNLSKMGHG
                     YSIYNTGTSIQTMLTLGSDLGTPSDVKNYITDKDGVLVRSYNTSTMTTWGSGYTWGNG
                     AQMNGFFAKQGYGLTSSWTVPITGTDTSFTFTPYAAKTDNIRTNYFKGRGKVVESSTT
                     SQSLSQSKSLSVSASQSASASASTSASESASTSASASASTSASASASTSASASASTSA
                     SASASTSASESASTSASASASTSASASASTSASASASTSASASASTSASASASTSASA
                     SASTSASASASTSASESASTSASESASTSASASASTSASASASTSASASASTSASASA
                     STSASASASTSASASASTSASESASTSASASASTSASASASTSASASASTSASESAST
                     SASASASTSASASASTSASASASTSASASASTSASASASTSASASASTSASASASTSA
                     SASASTSASASASTSASESASTSASASASTSASASSSTSASASASTSASASASTSASA
                     SASTSASASASTSASESASTSAS"
     gene            complement(2286..2399)
                     /locus_tag="VQU30_001683"
                     /pseudo
     CDS             complement(2286..2399)
                     /locus_tag="VQU30_001683"
                     /inference="COORDINATES: protein motif:HMM:TIGR03715.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="KxYKxGKxW signal peptide domain-containing
                     protein"
     gene            complement(2637..3098)
                     /locus_tag="VQU30_001684"
     CDS             complement(2637..3098)
                     /locus_tag="VQU30_001684"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000514209.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HET2447753.1"
                     /translation="MGKERRKQGNLERKKRVVKKRKIPLEELKAFVEAHPDAFLREIA
                     ARFDCALPSVWAVLKQIKVILKKTTSFREQKPEKVSEFLDILDNLKDLPVLYIDETGI
                     NRYLYRPYAGAPRGEKVYDKISGRRFERTNEVEQKLNGSFLIRYIDSQIRE"
     gene            complement(3065..3208)
                     /locus_tag="VQU30_001685"
     CDS             complement(3065..3208)
                     /locus_tag="VQU30_001685"
                     /inference="COORDINATES: protein motif:HMM:NF013842.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HET2447754.1"
                     /translation="MAYSTDFKQGALDSIKEGHSHVEAAKFFGVGVRTLFTWEKKDVN
                     KGT"
     gene            3477..3857
                     /locus_tag="VQU30_001686"
     CDS             3477..3857
                     /locus_tag="VQU30_001686"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000221621.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HET2447755.1"
                     /translation="MTYLEKWFDFNRRQKEIESLLEETIAQQSEQSLTLKEFYLLYYL
                     DLAEEKSLRQIDLPDKLHLSPSAVSRMVARLEAKNCGLLSRMCCHQDRRSSFICLTND
                     GQKTLASLQKTVEESLEAGLDFLI"
     gene            3956..4177
                     /locus_tag="VQU30_001687"
     CDS             3956..4177
                     /locus_tag="VQU30_001687"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4649 family protein"
                     /protein_id="HET2447756.1"
                     /translation="MIEITYIDASKNERTVTFESYEDFERSQQACLIGVADYYPVQKL
                     TYKGHNLDYHGTYGDIFFYLMKQDLSQYN"
     gene            4194..4508
                     /gene="trxA"
                     /locus_tag="VQU30_001688"
     CDS             4194..4508
                     /gene="trxA"
                     /locus_tag="VQU30_001688"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003004519.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin"
                     /protein_id="HET2447757.1"
                     /translation="MAKAITDATFEQETKDGLVLVDFWATWCGPCRMQGPILDKLSEE
                     LSEDVLKIVKMDVDENPNTARAFGIMSIPTLLFKKDGQVVKQVAGVHTAEQIKAIIAE
                     LS"
     gene            4815..5348
                     /gene="queF"
                     /locus_tag="VQU30_001689"
     CDS             4815..5348
                     /gene="queF"
                     /locus_tag="VQU30_001689"
                     /EC_number="1.7.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000828792.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADPH-dependent 7-cyano-7-deazaguanine reductase
                     QueF"
                     /protein_id="HET2447758.1"
                     /translation="MKHQSALVVFSGGQDSTTCLFWTMQHYETVEAVTFAYGQHHHLE
                     IQITREIAKEQGIRHHILDMSLLGQITAQPDFATIHISYIPDKLCVESKSLKLYLFSY
                     RNHGDFHENCINTIGKDLVNLLDPRYLEVWGKFTPRGGISIDPYYNYGKQGTKYEGLA
                     EQRLFQHDLYPEKIDNR"
     gene            complement(5602..6270)
                     /locus_tag="VQU30_001690"
     CDS             complement(5602..6270)
                     /locus_tag="VQU30_001690"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000714831.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aquaporin"
                     /protein_id="HET2447759.1"
                     /translation="MKKFVAELIGTFMLVFVGTGAVVFGNGLDGLGHLGIAFAFGLAI
                     VVAAYSIGTVSGAHLNPAVSIAMFVNKRLSSSELVNYILGQVVGAFIASGAVFFLLSN
                     SGMSTASLGENALANGVTVFGGFLFEVIATFLFVLVIMTVTSESKGNGAIAGLVIGLS
                     LMAMILVGLKITGLSVNPARSLAPAVLVGGAALQQVWIFILAPIAGGVLAALVAKNFL
                     GTEE"
     gene            complement(6381..6935)
                     /locus_tag="VQU30_001691"
     CDS             complement(6381..6935)
                     /locus_tag="VQU30_001691"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2785 domain-containing protein"
                     /protein_id="HET2447760.1"
                     /translation="MYQDLLRKIAEEKPNYNQEEIQWLFDHLGNPSPEIRNVLLNQGL
                     HYLSKEKDTRGFSSQYGWVHAFAHGADLLTEVVCHPGFPKNRVHEVFEILGQLFKRMS
                     IRFTDDEDWRLARVIYEPILQGKLAQEQVASWIKTVDFPIEEREDFYKFSNFRSCLVE
                     VYVQLDQRNSLQDELKEAIQSFQY"
     gene            complement(7181..8977)
                     /gene="pepF"
                     /locus_tag="VQU30_001692"
     CDS             complement(7181..8977)
                     /gene="pepF"
                     /locus_tag="VQU30_001692"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000435555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligoendopeptidase F"
                     /protein_id="HET2447761.1"
                     /translation="MEQKHRSEFPEKELWDLTALYQDREDFLRAIEKAREDINQFSRD
                     YKGNLHTFEDFEKAFAELEQIYIQMSHIGNYGFMPQTTDYSNDEFANIAQAGMEFETD
                     ASVALTFFDDALVAADEEVLDRLGKLPHLTAAIRQAKIKKAHYLGADVEKALTNLGEV
                     FYSPQDIYTKMRAGDFEMADFEAHGKTYKNSFVTYENFYQNHEDAEVREKSFRSFSEG
                     LRKHQNTAAAAYLAQVKSEKLLADMKGYDSVFDYLLAEQEVDRVMFDRQIDLIMKDFA
                     PVAQRYLKHVAKVNGLEKMTFADWKLDLDSALNPEVTIDDAYDLVMKSVEPLGQEYCQ
                     EVARYQEERWVDFAANSGKDSGGYAADPYRVHPYVLMSWTGRLSDVYTLIHEIGHSGQ
                     FIFSDNHQSYFNAHMSTYYVEAPSTFNELLLSDYLENQSNDPRQKRFALAHRLTDTYF
                     HNFITHLLEAAFQRKVYTLIEEGETFGASKLNSIMKEVLTDFWGDAIEIDDDATLTWM
                     RQAHYYMGLYSYTYSAGLVISTAGYLHLKHSETGAEDWLNLLKSGGSKTPLESAMIIG
                     ADISTDKPLRDTIQFLSDTVDQIISYSAELGE"
     gene            complement(8988..9731)
                     /locus_tag="VQU30_001693"
     CDS             complement(8988..9731)
                     /locus_tag="VQU30_001693"
                     /EC_number="2.1.1.193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001188214.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (uracil(1498)-N(3))-methyltransferase"
                     /protein_id="HET2447762.1"
                     /translation="MQQYFVKGSAVSPVTIEDRETSKHMFQVMRLKEEDEVTLVFDDG
                     IKRLARVLDMENRQFELVQELNDNVELPVQVTIASGFPKGDKLEFITQKVTELGASQI
                     WAFPADWSVAKWDGKKLGKKVEKLEKIALGAAEQSKRNVVPSIHLFENKADFLAQLDQ
                     FDRILVAYEEAAKEGEAAALIKAVTGLEKGAKLLFIFGPEGGLSPAEIENFEAKGAVL
                     AGLGPRILRAETAPLYALSALSVLVELEK"
     gene            complement(9733..10683)
                     /locus_tag="VQU30_001694"
     CDS             complement(9733..10683)
                     /locus_tag="VQU30_001694"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000451122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L11 methyltransferase"
                     /protein_id="HET2447763.1"
                     /translation="METWQELKVTVKREGEELVSNLLIELGAQGVAIEDSMDYMGNVD
                     RFGEIFPEVEQQEEIVVTAYYPDTVDMTVVEADLQARLAELTDFMDLGELKIGTTALA
                     EEDWADNWKKYYEPARITHDLTIVPSWTDYEATAGEKIIKLDPGMAFGTGTHPTTKMS
                     LFALEQVLRGGETVLDVGTGSGVLSIASSLLGAKEIFAYDLDDVAVRVAQENIELNTG
                     MENIHVAAGDLLKGVEIEADVIVANILADILIHLTEDAYRLVKDEGYLIMSGIIKDKW
                     DMVRQSAESAGFFLETHMIQGEWNACVFKKTKDISGVIGG"
     gene            complement(10821..11249)
                     /locus_tag="VQU30_001695"
     CDS             complement(10821..11249)
                     /locus_tag="VQU30_001695"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000418166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HET2447764.1"
                     /translation="MELEISDFQGCKIALFCGDKLLTILRDDKDDIPCPNMWELPGGG
                     REGDESPFECARREVYEELGIHLDEDCLLWSKIYPSVIFKGKKSVFMVGQLRQEQFDN
                     IIFGDEGQGYQLMNVEEFLSSSQVVPQLQERLKDYLKVSD"
     gene            complement(11230..12318)
                     /locus_tag="VQU30_001696"
     CDS             complement(11230..12318)
                     /locus_tag="VQU30_001696"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000719715.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-2 protease family protein"
                     /protein_id="HET2447765.1"
                     /translation="MKKIGTYLVYVLAVVFIMLAFACGTIAFAELGYSAVLAFTFGYA
                     FALLSMYLIFILHELGHAFCGYLTGYRLVAFGLGHFILTKKSGRFHLSRTAILKNVGA
                     QYIGLKEDESDQRIILMLSGGLMVHLGLILLAIVFGFLTRSWYFAGTWIFLNLSFFLN
                     NILPVDITDGAKIWELLQHPENTKYAYLVLRHSAQTLLAPQEYDLKDFVQAVPEDARG
                     SFADGVLGMQGEVSILEGKEEVAKQQFQALLERTTTPMMQTVAQLSLLHIALLEGDFE
                     QAEQYASIRQVKSFLSLKLSNLQVIQAWYQLKVKKDVDRTRKALKIARQKMDSSRMLR
                     DEKRYYENLLAELEKEMLEGTEDGTRNF"
     gene            complement(12337..12807)
                     /locus_tag="VQU30_001697"
     CDS             complement(12337..12807)
                     /locus_tag="VQU30_001697"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000257105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3013 family protein"
                     /protein_id="HET2447766.1"
                     /translation="MATYGFLDVLEEELDKNFPFDFEISWDKRNHAVEVSFLLEAQNA
                     AGVEMVDEDGEVSSDDILFEEAVLFYNPAKSTVNEEDYLTVIPYLPKKGFSREFLAYF
                     VLFLKDTAEVGLDVLMDFLEDPEAEEFVMEWNQEVFEEGKVGLEEGEFYPYPRY"
     gene            complement(13098..13550)
                     /locus_tag="VQU30_001698"
     CDS             complement(13098..13550)
                     /locus_tag="VQU30_001698"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000961815.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system HicB family
                     antitoxin"
                     /protein_id="HET2447767.1"
                     /translation="MLVTYPALFYYDDTDGTEATYFVHFPDFEYSATQGEGISEALAM
                     GSEWLGITVADLIESDGELPQPSDINSLSLIDNDPFKDDEDFVSTYDLDKSFISMVSV
                     DVSEYLGSQEPIKKTLTIPKWADKLGREMGLNFSQTLTDAIADKKVQA"
     gene            complement(13587..13766)
                     /locus_tag="VQU30_001699"
     CDS             complement(13587..13766)
                     /locus_tag="VQU30_001699"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397531.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system HicA family
                     toxin"
                     /protein_id="HET2447768.1"
                     /translation="MPMTQKEMVKLFTAHGWIKTRGGKGSHIKIEKQGERPITILHGE
                     LNKYTERGIGKQAGL"
     gene            complement(13903..14082)
                     /locus_tag="VQU30_001700"
     CDS             complement(13903..14082)
                     /locus_tag="VQU30_001700"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2447769.1"
                     /translation="MNLIFEEYQFVKIGDKKYRVRSGPMIHSTPPQSVLDRDTFTIDY
                     TDDELLDKEAVFTTH"
     gene            complement(14247..>14432)
                     /locus_tag="VQU30_001701"
     CDS             complement(14247..>14432)
                     /locus_tag="VQU30_001701"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000818079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2447770.1"
                     /translation="IFTKQIRHWILSDQVISGKRKLFFREDTPKEILDLYENIKSKLD
                     FAYQEVHSNNGLKKYEK"
BASE COUNT         4196 a         3287 c         2765 g         4184 t
ORIGIN      
        1 gacgcactcg ttgaggctga ctcagacgca ctcgttgagg ctgaagctga cgcactcgtt
       61 gatgctgaag ccgaggcact ggttgacgct gaagctgagg cgcttgttga tgctgaggct
      121 gatgcgcttg tgcttgatga agctgaggca cttgttgatg ctgaggctga cgcactcgtt
      181 gatgcagatt cagacgcact tgtgcttgct gaggctgacg cactggttga tgcggaagct
      241 gaggcgcttg tgcttgctga agccgacgca ctcgttgagg ctgaagctga agcgcttgtc
      301 gatgctgagg ctgacgcact tgtcgacgct gaagctgaag cactggttga cgctgaagct
      361 gaggcactgg ttgacgctga agctgacgcg ctggttgagg ctgaggctga ggcgctagta
      421 cttgctgact ctgatgcact ggtacttgct gaggctgacg cacttgtgct tgctgaagcg
      481 gacgcactcg ttgatgctga agctgaagca ctggtacttg ctgactctga tgcactggta
      541 cttgctgagg ctgacgcact tgtgcttgct gaagccgatg cactcgttga tgcggaagct
      601 gatgcacttg ttgatgcgga agctgatgca ctcgttgatg ctgaagctga ggcgctagta
      661 cttgctgagg ctgaggcact ggttgatgcc gattcagatg cactggttga ggccgattca
      721 gacgctgagg tacttgctga agctgacgca ctggttgacg ctgaagctga tgcactggtt
      781 gacgctgagg ccgaagcact ggtacttgct gaagccgacg cactggtgct tgctgaagcc
      841 gaggcgctag tgcttgctga agccgacgca ctcgttgatg cggaagctga cgcactcgtt
      901 gatgcagatt cagacgctga ggtacttgct gaagctgagg cactcgttga tgcggaagct
      961 gacgcactcg ttgatgctga ggctgaggca cttgtacttg ctgaggctga tgcgctggtt
     1021 gaggccgatt cagaagctga ggtgcttgct gaggctgagg cgctttgact agcacttact
     1081 gagagtgact tagactgtga aagtgactga ctggtcgtgc tagattcaac tacctttcct
     1141 ctacccttga agtagttagt tctaatgtta tctgttttag cagcgtaagg ggtaaatgta
     1201 aaggatgtat ccgttccagt aattggtaca gtccaagatg atgttaatcc atatccttgc
     1261 ttagcaaaga aaccattcat ttgggcacca tttccccaag tatacccact accccacgtc
     1321 gtcattgtag atgtattata ggatcgaacc agtacaccat ctttgtcagt aatgtagttc
     1381 tttacatctg aaggggtacc aagatcactg ccaagggtta acattgtttg tattgaagta
     1441 cctgtattat agatagaata cccatgaccc atctttgaaa gattaccaag agcccttgtg
     1501 gtaggatcta catacgtaac cgtataggta aaggtcagtt ttgaaccatc atttgtcact
     1561 gtcaatttat agtaaattgg aacatgatat accgaatcta aacctgtacc tgtataaact
     1621 tttgtctcac ttttagcaat gtttagactt gcattaattg caggggcgcc atttacaatc
     1681 gtattgccag aaaaaacagc agcttttata gaagccagca attgctcgat ggaatccact
     1741 gaacgcttgc gtcgcttagc ataagattgg agattgacat ttgtaactga tgctgcataa
     1801 tcactagctg gtttcttacg atcttcttcg accttcttag cagttgcttc tgtagcggca
     1861 gctgtttgtg atcctaccac agtagatgat gcagagatac ttgtcgaagc cgatgtactt
     1921 gctgattctg atgcacttgt actcgctgag gtcgaagcgc tggttgaggc tgactcagat
     1981 gcagatgtac ttgccgactc tgaagctgac aaactagttg aactcgctga attacttgta
     2041 gatatcgtac ctagaactac tgtatcattt gttgccaaag catccgtttt ctctacagtt
     2101 ttttcaagta ctgccgactc atttgtaaat accttcgttt gagttgcaac ggttccactt
     2161 atgacagttc ccgcagcaac tattcccttg aggatatcaa gcccagtaat tgaatgactt
     2221 actttatctt ctaccgtttc ggtcatgacc tgagtagtat caacaccacc acgcatgacc
     2281 ttaaacaagc caaaaagaga agtcgaggcc cgtagccaat gcttccctga tttgattaat
     2341 ttgaaccgag ttactcggtc tgtttctcta tattcaccct tctgacgtct aaaaaatatt
     2401 ttgaaatttc ctttcgagta ttattttcat gtatggatat aaataaatta ccatactata
     2461 attatagaat agggaaccca aaatagcaag aaacttgagg tatttttgct aaaaaaaaaa
     2521 agcattttac tattttatat atatattata agataagttt tttataaaga cacgcaaatg
     2581 agtataaatc agctaatttt tggtttatat tcctattttt atgcataatt attctttcat
     2641 tctctaattt gtgaatcaat atatctgatt agaaaactac cattgagttt ttgctccacc
     2701 tcattagtcc gctcaaaacg ccgtccgcta atcttgtcat agactttctc ccctctagga
     2761 gcccctgcat aaggacgata gaggtagcgg ttgattcccg tttcgtcaat atataggact
     2821 ggtaaatctt ttaggttatc caaaatatca agaaactcag aaactttctc aggcttttgt
     2881 tccctaaaac tggtcgtctt ttttaaaatg accttaatct gctttaaaac tgcccatacg
     2941 gagggcaaag cacaatcaaa acgggccgca atttcccgta aaaaagcgtc tggatgagcc
     3001 tctacaaagg ctttcaattc ttctaaaggg atcttacgct ttttgacgac tcgctttttc
     3061 cgctctaagt tcccttgttt acgtctttct tttcccacgt gaagagagtt ctgacgccaa
     3121 caccaaaaaa cttggctgcc tcgacatgac tgtgcccctc tttgatggaa tctaatgctc
     3181 cttgtttaaa atcagtacta tatgccatag ctttattaga ccatgcttat tttaaactaa
     3241 gcaactatag atagagaaat gaaataaaat ctaaattcga atgtgataag gagttagaaa
     3301 ttgaaacaat aggattcccc cattattcac acaaaaataa aaccactaaa aaacagagct
     3361 tgccagcatt cttgaaaagt agtataatta ttgcatgcgc aatcatcttg tgacgcagag
     3421 actgcccgtt aatggacttt cttctatatt atgactctaa aaagaaagga gacactatga
     3481 cctatttgga aaaatggttt gacttcaatc ggcgtcagaa agaaattgaa agtctcttgg
     3541 aagagaccat tgcccaacag agcgagcaaa gtctgacctt gaaagagttc tacctgctct
     3601 actatctgga cttggctgaa gaaaaatctc tacgccagat tgacctgcca gataaacttc
     3661 atctgagccc gagcgcagtt tctaggatgg tggctcgctt ggaagctaaa aattgcggtc
     3721 tactcagtcg catgtgttgc catcaagata gacgctctag ttttatctgc ctgacaaatg
     3781 atgggcaaaa gacactggcc tcgctacaaa agactgtcga agaaagcttg gaagcaggtt
     3841 tggatttctt gatttaagat gattttaaaa aaagttgcgt gcgcaatcat ttttcttgac
     3901 attctctttt ataaggagta aaataaagtt agcattaaac aaaggagttt taaatatgat
     3961 tgaaattacc tatatagatg ccagcaagaa cgaaagaact gtgactttcg agtcttatga
     4021 agactttgaa cgttcacaac aagcttgcct tatcggcgtc gcagactact accctgtcca
     4081 aaaattaact tacaagggtc ataatttgga ctaccatggg acttatggag atatcttctt
     4141 ctatctcatg aaacaagatt taagccaata taactaaaaa aaggagaaat acaatggcaa
     4201 aagcaattac agatgcaaca ttcgaacaag aaacaaaaga cggtttggtc ttagtagact
     4261 tctgggcaac ttggtgtggt ccatgtcgta tgcaaggtcc aatcttggac aaattgtctg
     4321 aagaactttc agaagatgtc ttgaaaatcg ttaaaatgga cgttgatgaa aatccaaaca
     4381 cagctcgtgc ttttggaatc atgtctattc caactcttct cttcaaaaaa gacggccaag
     4441 ttgtcaaaca agttgcaggt gttcacacag cagaacaaat caaggccatc attgctgaat
     4501 tgagctaatc aaacgagaga ccaagtactt tctttggtct cttttttctt gccctttgcc
     4561 atttttcaaa aaatatgcta gactatagta gattgaaact agaatagtac acctctactt
     4621 ctaaaacatt gttaaaaatc gatttgactg tcctgatcga tttgtcctgt ttttatttca
     4681 ttttactata taagtagaat attacgatgt ttgggatatg ccatcgctaa aaaaaaactc
     4741 gatttggtat tttttagttc cctaatggga gctttttgcg tgctctgaac atttcccatt
     4801 ttggaaggag tactatgaaa catcaatcag ccttggtcgt ctttagtggc ggtcaagatt
     4861 caacaacctg ccttttctgg accatgcaac actatgaaac agtcgaagct gtcacctttg
     4921 cctacggcca acatcatcac ctcgaaattc aaattactag agaaatcgct aaggaacagg
     4981 gcattcgtca ccatatcctc gatatgtctc tgctgggaca aatcactgct cagccagact
     5041 ttgcgacgat tcatatttcc tacattcctg acaagctctg tgtcgagtca aaatccctca
     5101 aactatatct atttagctac cgaaaccacg gagatttcca cgaaaactgt atcaacacca
     5161 tcgggaaaga cttggtcaac ttgctagacc ctcgctattt agaagtctgg ggaaaattca
     5221 ctccgcgcgg tggcatttca atcgacccct actataacta cggtaagcaa ggaactaagt
     5281 atgagggctt ggcagaacaa cgcctcttcc aacacgacct ttatccagag aaaattgaca
     5341 accgctaaag tcatactcaa tgaaaatcaa agagcaaact aggaagttag ccgcaggtta
     5401 ctcaaagcag tgtttgaggt tgtagataaa actgacgaag tcagatcaaa acactgtttt
     5461 gaggttgtgg atagaactga cgtagtcagt aaccatacct acggcaaggt aaagctgacg
     5521 tggtttgaag agattttcga agagtatcat acgaaaaagc cctgttcctc aagatgagga
     5581 gcaaggcttt ttgagtttca attattcttc tgttccaagg aaattttttg caacaagggc
     5641 tgcaagaact ccaccagcga ttggtgcaag gatgaaaatc caaacttgtt gaagggctgc
     5701 gccgcctacc aagacagctg gtgccaagct acgagctggg tttactgaaa gtccagtaat
     5761 cttcaatccg acaagaatca tcgccatcaa tgacaaaccg attaccaaac cagcaatcgc
     5821 gccattgccc ttgctttctg aagtcacagt catgataacc aatacaaaca agaaagttgc
     5881 gatgacttca aacaagaaac caccaaagac agtgacaccg tttgccaagg cattttcacc
     5941 aagactagca gttgacatac ctgaattact caagaggaag aagactgcgc cagaagcgat
     6001 gaaagctcca acaacctgac caaggatgta gtttacaagt tctgaagatg acaaacgttt
     6061 gtttacaaac atagcaatcg aaacagccgg gttcaagtga gcacctgaaa cagttccgat
     6121 tgagtaggct gccaccacga ttgccaaacc aaaggcaaag gcgattccaa ggtgaccaag
     6181 gccatcaaga ccatttccaa aaacaacagc tcctgttcca acgaacacaa gcatgaacgt
     6241 accgattaac tcagcaacaa attttttcat tttctttctc cttttttcaa aaactagata
     6301 ctagtctatc aaaagtagga aagggtttca agaaaattga ttggaaattt tttgaaaatc
     6361 atagaactat tagctaatct ctagtattga aaagactgga tagcttcttt caactcatct
     6421 tgtaaactat ttctctggtc aagttggaca tagacttcca ccagacagga tctaaagttg
     6481 gaaaatttgt aaaaatcctc cctttcttct atcggaaaat caacagtttt tatccaagaa
     6541 gctacttgtt cttgcgctaa cttcccttgt aaaataggtt catagatcac tcttgctaaa
     6601 cgccaatcct catcatctgt aaagcgaatc gacattcttt taaataattg gccaagtatc
     6661 tcaaatactt catgaactct gtttttagga aagcccggat gacaaaccac ctctgtcagt
     6721 aaatcggctc catgtgcaaa agcatgaacc caaccatact gacttgaaaa accccttgta
     6781 tccttttctt ttgaaagata gtgcaagcct tgatttaaaa ggacattacg aatttctgga
     6841 gaaggatttc ccaaatgatc aaacaaccac tggatttctt cctggttata atttggtttt
     6901 tcttctgcta tttttcttag taaatcttga tacatggtca atacctctac atttctagca
     6961 actgttcaaa aaggcagtct taaatgactc aatattgaat tctcaattaa atacaatctg
     7021 atataaaatg acgtaaataa ctatcaatac cagttctaca gtaagttcaa atttaacatc
     7081 acgatcttca acgacatttt tgaaaatagc tacaactaag acaaatagaa tgacgcttaa
     7141 caagcccata aacatcattc taaaaaattt ttctattccc ctactctccc aactcagcac
     7201 tataggagat aatctggtca actgtgtcag acaagaattg gatggtatca cggagtggtt
     7261 tgtctgttga aatatcagca ccgataatca tggctgactc aagtggtgtc ttgctaccac
     7321 ctgatttgag gagattgagc cagtcttcag ctccagtttc agaatgtttt agatgaaggt
     7381 aaccagcagt cgagataact agtcctgctg agtaagtgta actatacaag cccatatagt
     7441 agtgagcttg gcgcatccaa gtcagagttg catcatcgtc aatttcaata gcatctcccc
     7501 agaaatccgt caaaacttcc ttcataatgc tgttgagctt gcttgctcca aaggtctccc
     7561 cttcttcaat caatgtatac accttacgct ggaaggcggc ttccaagagg tgggtgataa
     7621 agttatggaa gtaggtgtct gtcaagcgat gagccagagc gaagcgtttt tgacgtgggt
     7681 cattagactg gttctccaag taatcactga gtagcaattc attgaaggtt gacggtgctt
     7741 caacatagta ggtcgacata tgggcattga agtaactttg atgattgtct gaaaagatga
     7801 attgaccaga atgcccgatt tcatgaatca aggtatagac atcgctcaaa cggcctgtcc
     7861 agctcatgag tacataaggg tgtacgcgat atgggtccgc cgcataacca ccggaatcct
     7921 tgccactgtt agcagcaaag tccacccagc gctcttcttg gtaacgagca acttcctgac
     7981 aatattcttg ccccaaaggt tctaccgact tcatgaccaa atcataggca tcgtcaatag
     8041 tcacttcagg attcagggcg ctgtccaagt ccaatttcca gtctgcaaag gtcatctttt
     8101 caagaccatt taccttggca acatgcttga ggtatctctg agcgactggt gcaaagtcct
     8161 tcatgatgag gtcaatctgg cggtcaaaca tgacacggtc cacttcttgt tcagctagaa
     8221 gatagtcaaa gacagagtcg tatcccttca tatcagccaa gagtttttca gacttgacct
     8281 gagccagata ggctgctgca gccgtatttt ggtgcttacg aagtccctct gagaaggaac
     8341 ggaaggattt ctcacgaacc tcagcatcct catggttttg gtagaaattc tcataggtca
     8401 caaagctgtt tttgtaggtc ttgccatggg cttcaaagtc agccatttca aaatccccag
     8461 ctcgcatctt agtataaatg tcctgcggac tgtagaaaac ttcaccgaga tttgtcaagg
     8521 ccttctccac atctgcccct aagtagtggg cttttttgat tttagcctga cgaatggcag
     8581 ctgttaaatg tggcaattta cccaaacgat ccaagacttc ctcgtctgct gccaccaagg
     8641 catcgtcaaa aaaggtcaag gctacgctgg catctgtttc aaattccatc ccagcttgag
     8701 caatatttgc aaattcgtca ttgctatagt ccgtcgtctg aggcataaaa ccatagttgc
     8761 caatatggct catctgaatg tagatctgtt ccaattccgc aaaggccttc tcgaaatcct
     8821 caaaagtgtg aagattgccc ttgtaatcac ggctaaactg gttgatgtct tcgcgagctt
     8881 tctcgattgc acgcaagaaa tcctcacggt cttggtatag agctgttaaa tcccaaagtt
     8941 ccttctctgg aaattctgaa cggtgttttt gttccatttt cttcctctta tttctctaat
     9001 tctactaaaa cactaagggc tgataaggcg taaagcggtg ctgtttctgc tcttagaatg
     9061 cgagggccaa gtcctgccaa aacagctccc ttagcttcaa aattttcaat ttccgcaggt
     9121 gacagaccac cttctggacc aaagataaag agcaatttgg ctcctttctc gagtccagta
     9181 actgctttta taagagcagc ggcttctcct tctttggccg cctcttcata ggctactaag
     9241 atgcggtcaa actggtcaag ttgggctaga aagtctgctt tattctcgaa aagatggata
     9301 cttggaacaa cattacgctt actttgctct gctgctccaa gagcaatttt ttctagtttt
     9361 tcaacctttt tacccaattt cttgccatcc cacttagcaa cggaccaatc ggcagggaag
     9421 gcccaaatct ggctggcacc tagttccgtc accttttgag tgataaactc caacttatct
     9481 cccttgggaa atccagatgc gatggtcact tggactggta gttccacatt gtcatttaat
     9541 tcttggacca actcaaactg acgattttcc atatccagca cgcgcgccaa gcgcttgatg
     9601 ccatcatcaa agactaaggt aacctcatcc tcttctttca agcgcataac ctgaaacata
     9661 tgcttgctgg tttccctgtc ctcgatggtg acaggagaga ctgcactccc cttgacaaaa
     9721 tactgttgca tgctagcctc caatcacacc tgaaatatcc ttggtcttct tgaagacgca
     9781 ggcattccat tccccttgaa tcatatgggt ttcaaggaaa aatccagctg actcagccga
     9841 ctggcgcacc atgtcccact tgtccttgat aatgccactc atgatgaggt agccttcatc
     9901 ctttaccaag cgataagcat cctccgtcag atgaatgaga atatccgcca agatattagc
     9961 cacgatgaca tctgcttcaa tctcaactcc cttaagcaag tctcctgctg ctacatggat
    10021 attttccata ccagtgttga gctcaatatt ttcctgagcg acacgaaccg ccacatcatc
    10081 caagtcatag gcgaaaatct ccttggcacc taggagtgag cttgcaatag aaagaacccc
    10141 tgaaccagtc cccacatcta gcaccgtttc gccaccacga agaacctgtt ccaaggcaaa
    10201 aaggctcatc ttggtagttg ggtgggttcc agtaccaaaa gccatgccag gatccagctt
    10261 gataattttt tctcccgcag tcgcctcata gtctgtccaa gagggaacga tggtcaaatc
    10321 atgagtgatg cgagcaggtt catagtattt cttccagttg tctgcccagt cttcctcagc
    10381 caaggcagtc gtacctattt ttaactctcc caaatccata aaatccgtca attctgctaa
    10441 gcgagcctgc aagtccgcct caaccactgt catatccacc gtgtcagggt agtaggctgt
    10501 cactacgatt tcttcttgct gctccacctc tgggaaaatc tcgccaaaac gatccacatt
    10561 tcccatatag tccatgctgt cttcaatcgc gactccttgc gctcccagct caatcaagag
    10621 attggaaacc aactcctctc cctcacgctt cactgtaact tttaactctt gccatgtttc
    10681 cattattaag ataccaagcc cgtaaaacac aaaaccaaaa taggaaattc tctgaagacg
    10741 cttgtgtcta agagaagttt atctttttgg cacagtgttt agggcgggtt cagtttagaa
    10801 atgtaactga accatccttt ctaatcactt acttttaaat aatcttttaa tctctcttgc
    10861 aactgaggca caacttgact ggaactaaga aattcctcaa cattcatcag ctgatagccc
    10921 tgtccttcat ctccgaagat gatattgtca aattgttctt gtcttagctg accaaccata
    10981 aagaccgatt tcttgccttt aaaaattacg ctaggataaa tcttgctcca aagcagacag
    11041 tcttcatcta aatgaattcc cagttcctca taaacttcac gccgagcgca ttcaaaaggg
    11101 ctttcgtccc cttcacggcc accacctggc aactcccaca tgttgggaca agggatatcg
    11161 tccttgtcat cacgcaaaat cgtcagtagc ttatccccac aaaagagggc aatcttgcaa
    11221 ccttggaaat cagaaatttc tagttccatc ttcagttcct tctaacattt ccttttccag
    11281 ctctgctaac aagttttcat aatagcgttt ctcgtccctc aacattcgac tactatccat
    11341 tttctgtcta gcaatcttga gagccttacg agttcgatct acatctttct tcacctttaa
    11401 ttgataccag gcttgtatca cttgaagatt ggacagtttg agagacagaa acgatttgac
    11461 ctgtcgaata ctagcatatt gctccgcttg ctcaaaatct ccttccaaca aggcgatatg
    11521 aagcagggat agttgggcaa ctgtctgcat catcggagta gttgtcctct caagtaatgc
    11581 ttgaaactgc tgtttagcta cttcttcctt cccttccaaa atggaaactt caccttgcat
    11641 acctaataca ccatccgcaa aactccctcg tgcatcctca ggaactgctt gaacaaagtc
    11701 tttcaaatca tattcttgag gagccagcaa agtttgagca gaatgtctca ataccaggta
    11761 ggcgtatttg gtattttcag ggtgttgtag taattcccaa atttttgctc catcggtgat
    11821 gtcgactggc aaaatgttat ttaggaagaa agataaatta agaaaaatcc aagtccctgc
    11881 aaaataccag cttcttgtca aaaatccaaa cactatcgcc aataatatca agccgagatg
    11941 aaccatcaag cctcctgaaa gcatcaggat gattctttga tcgctttcat cctcttttaa
    12001 accaatgtat tgagcaccaa catttttcag aatggctgtt ctactaagat gaaacctgcc
    12061 tgactttttg gtcaaaataa aatgtcctaa tccaaaagcc accagccgat agcctgtcaa
    12121 gtagccacaa aaagcatgac ccagctcatg aagaataaag attaaataca tgcttagaag
    12181 agcgaaggca taaccaaaag taaaggctaa aactgcggaa taccccaact ctgcaaatgc
    12241 gattgttcca caagcaaaag ctagcataat aaagacaaca gctagcacat aaaccaaata
    12301 agtcccaatt ttcttcataa cacctccaac caactcctag tatcttggat aaggataaaa
    12361 ttctccctct tccaagccaa cttttccttc ttcaaagact tcttggttcc attccatgac
    12421 aaattcctct gcttctgggt cttccaaaaa gtccatgagg acatctagcc caacctcagc
    12481 agtatcttta aggaaaagca caaaataagc taaaaattca cgggaaaatc cttttttagg
    12541 caggtaagga ataacagtca aatagtcttc ctcattgact gttgacttag caggattgta
    12601 gaaaaggacc gcttcctcaa aaagaatgtc atctgatgaa acctctccgt cttcatccac
    12661 catctccaca cctgcagcat tttgcgcttc caatagaaaa ctcacttcta ccgcatggtt
    12721 gcgtttgtcc cagctaatct caaagtcaaa gggaaagttc ttgtccaact cttcctctaa
    12781 aacatctaaa aatccgtatg ttgccatttt gtcctctttc tatgcgactc tttaatcgcc
    12841 ccgattgctc ggaaatatgc taaaatagat actaccatct taccacaaaa ttattttatg
    12901 tcctaattat accatattac ctcatttaaa cccttggtat cagtgatttt cttaaaagtc
    12961 tgatttcttc atttctcata aaaatcaata taaaaagccc tcgaaagggc taataaatct
    13021 ataaaatcaa taggcgagta actagcacaa gtggacgtgc ttttttattg actattacca
    13081 cgataccacg cttaatctta ggcttgaact ttcttatctg caatagcgtc tgtcaaagtc
    13141 tgagaaaagt taagtcccat ttctcgtccc aacttatctg cccattttgg tatggtcaaa
    13201 gtctttttaa tgggttcctg acttcctagg tattctgata catcaacaga taccatagaa
    13261 ataaaagatt tatcaaggtc ataggttgac acgaaatctt catcatcttt aaaaggatca
    13321 ttatcaatta aagacaagct attgatatct gatggctgag gtaactctcc atcactctct
    13381 atcaaatctg caacagttat ccctagccac tccgacccca tagccaaagc ctcagaaatc
    13441 ccctctcctt gtgtagctga gtattcaaaa tctgggaaat ggacaaaata agtcgcttct
    13501 gttccgtctg tgtcgtcata ataaaataaa gctggatacg taactaacat ttcactacct
    13561 ccatatcaaa aagcagggac tgaattttac aacccagctt gctttcctat ccctctttca
    13621 gtgtacttat tcagctcacc atgaaggatt gtgataggtc tttccccttg cttctcgatt
    13681 ttaatatggg agcctttacc gcctctagtc tttatccaac catgggccgt aaagagttta
    13741 accatctctt tttgtgtcat aggcatagcg cttttacctc ctgacaacac cattataaca
    13801 cgtgttacac gtattgtaaa ggagtgatac ttattattct attatacata aaagccccta
    13861 gatgtggttc taagggaaac caatttattc agacctattt ttctaatgag tagtaaaaac
    13921 tgcttcttta tcgagcaatt catcatctgt atagtcaatt gtaaaagtat ctcgatctaa
    13981 gacagattga ggcggagttg aatgaatcat aggaccactg cgtactctat attttttatc
    14041 tccaattttt acaaactgat actcttcgaa aatcaaattc aaaccacgtc aacgtcgcct
    14101 taccgtactc aagtacagcc tgcggctagt ttcctagttt gctctttgat tttcattgag
    14161 tatgattaac tctcaagtct tcgaaatcag gattttcaac agttattaca aggaggcgat
    14221 ttactacttc aaaaacatca attattctat ttttcatatt ttttcaaccc attattagaa
    14281 tgaacttctt ggtaagcaaa atcaagttta gatttaatgt tttcgtacaa atctaaaatc
    14341 tcttttggag tatcttcccg gaagaaaagt tttcttttcc ctgaaataac ttgatcacta
    14401 agaatccaat gacgaatttg ttttgtaaaa at
//
LOCUS       DAVBBO010000053        14416 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ST1
            SAMEA2066453-rid20184263.denovo.053, whole genome shotgun sequence.
ACCESSION   DAVBBO010000053 DAVBBO010000000
VERSION     DAVBBO010000053.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2066453
            Sequence Read Archive: ERR351777
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 14416)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14416)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980402.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980402.1
            Genome Coverage       :: 176x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:17:33
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,141
            CDSs (total)                      :: 2,104
            Genes (coding)                    :: 1,953
            CDSs (with protein)               :: 1,953
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 16S)
            partial rRNAs                     :: 1 (23S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 151
            CDSs (without protein)            :: 151
            Pseudo Genes (ambiguous residues) :: 0 of 151
            Pseudo Genes (frameshifted)       :: 73 of 151
            Pseudo Genes (incomplete)         :: 76 of 151
            Pseudo Genes (internal stop)      :: 40 of 151
            Pseudo Genes (multiple problems)  :: 32 of 151
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14416
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2066453-rid20184263.denovo.053"
                     /strain="ST1"
                     /db_xref="taxon:1313"
     gene            complement(10..1299)
                     /locus_tag="VQU30_001702"
     CDS             complement(10..1299)
                     /locus_tag="VQU30_001702"
                     /EC_number="6.1.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine--tRNA ligase"
                     /protein_id="HET2447771.1"
                     /translation="MKLQKPKGTQDILPAESAKWQYVEGFAREIFKRYNYAEVRTPIF
                     EHYEVISRSVGDTTDIVTKEMYDFYDKGDRHITLRPEGTAPVVRSYVENKLFAPEVQK
                     PSKFYYMGPMFRYERPQAGRLRQFHQIGVECFGSSNPATDVETIAMAAHFLKEIGIQG
                     VKLHLNTLGNPESRAAYRQALIDYLTPLKETLSKDSQRRLEENPLRVLDSKEKEDKVA
                     VENAPSILDFLDEESQAHFDAVRQMLENLGVDYIIDTNMVRGLDYYNHTIFEFITEIE
                     GNDLTVCAGGRYDGLVAYFGGPETAGFGFGLGVERLLLILEKQGVTLPIENALDVYIA
                     VLGEGANIKALELVQALRQQGFKAERDYLNRKLKAQFKSADVFAAKTLITLGESEVES
                     GQVTVKNNQTREEVQVSLETISQNFSEIFEKLGFYTQ"
     gene            complement(1377..2624)
                     /locus_tag="VQU30_001703"
     CDS             complement(1377..2624)
                     /locus_tag="VQU30_001703"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transporter"
                     /protein_id="HET2447772.1"
                     /translation="MKLLFRNPAYRILTLSRFFNAFGVSIFNLVFIVYASTLSQASFA
                     VAMANIVMILPTLFTVFAGIRADYTRDKVKWMVYSGLFQAVLFFLAALVVQQASLFAF
                     SSLCLINVISDIISDFAGGLRMPLIKEKVAEDDLMEAYSFSQFITYISAIGGQAFGVW
                     LLALSVNNFSLVAGINACFFLVSATILFLGKSKLSLSMSSADGENLKNEKLSIKDQFL
                     TIYRNLRLVFLKSGQKNFGFMLFAVLLINSLGGALGGIYNIFFLSHSLLNFSYTEALF
                     INQFCVLVSVIISSLTGNDYFGKQSLPRLMMWETVGLSLVGLANLFNQVVLGLLFLFF
                     TLYVSGKVQPKISAMLMKNLAPEVLARTSNFLGLLFTLSIPVGTACFSLVAVWNIQLT
                     WMLFVGLSLLAIFLTILNLKNDI"
     gene            complement(2815..3665)
                     /gene="rgg"
                     /locus_tag="VQU30_001704"
                     /pseudo
     CDS             complement(2815..3665)
                     /gene="rgg"
                     /locus_tag="VQU30_001704"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398326.1"
                     /note="Rgg, as the term is used in Streptococcus
                     pneumoniae, is the lone quorum-sensing system
                     transcriptional regulator related to proteins Rgg1, Rgg2,
                     Rgg3, and Rgg4 of Streptococcus pyogenes.; frameshifted;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="quorum-sensing system transcriptional regulator
                     Rgg"
     gene            3789..4130
                     /locus_tag="VQU30_001705"
     CDS             3789..4130
                     /locus_tag="VQU30_001705"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003080443.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-sulfur cluster assembly factor"
                     /protein_id="HET2447773.1"
                     /translation="MRDDIKINDRALALQDQIIEKLEKVFDTDVELDVYNLGLIYEIN
                     LDETGLCKIVMTFTDTACDCAESLPIEIVAGLKQIEGIKDIKVEVTWSPAWKITRISR
                     YGRIALGLPPR"
     gene            4188..4268
                     /locus_tag="VQU30_001706"
                     /pseudo
     CDS             4188..4268
                     /locus_tag="VQU30_001706"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820552.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopyranose mutase"
     gene            complement(4474..6177)
                     /gene="ilvD"
                     /locus_tag="VQU30_001707"
     CDS             complement(4474..6177)
                     /gene="ilvD"
                     /locus_tag="VQU30_001707"
                     /EC_number="4.2.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000137341.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroxy-acid dehydratase"
                     /protein_id="HET2447774.1"
                     /translation="MTELDKRHRSSIYDSMVKSPNRAMLRATGMTDKDFETSIVGVIS
                     TWAENTPCNIHLHDFGKLAKEGVKSAGAWPVQFGTITVADGIAMGTPGMRFSLTSRDI
                     IADSIEAAMSGHNVDAFVAIGGCDKNMPGSMIAIANMDIPAIFAYGGTIAPGNLDGKD
                     IDLVSVFEGIGKWNHGDMTAEDVKRLECNACPGPGGCGGMYTANTMATAIEVLGMSLP
                     GSSSHPAESADKKEDIEAAGRAVVKMLELGLKPSDILTREAFEDAITVTMALGGSTNA
                     TLHLLAIAHAANVDLSLEDFNTIQERVPHLADLKPSGQYVFQDLYEVGGVPAVMKYLL
                     ANGFLHGDRITCTGKTVAENLADFADLTPGQKVIMPLENPKRADGPLIILNGNLAPDG
                     AVAKVSGVKVRRHVGPAKVFDSEEDAIQAVLTDEIVDGDVVVVRFVGPKGGPGMPEML
                     SLSSMIVGKGQGDKVALLTDGRFSGGTYGLVVGHIAPEAQDGGPIAYLRTGDIVTVDQ
                     DTKEISMAVSEEELEKRKAETTLPPLYSRGVLGKYAHIVSSASRGAVTDFWNMDKSGK
                     K"
     gene            complement(6410..7342)
                     /locus_tag="VQU30_001708"
     CDS             complement(6410..7342)
                     /locus_tag="VQU30_001708"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transketolase family protein"
                     /protein_id="HET2447775.1"
                     /translation="MMRSTKELRHVYRDFLLEANQSDSDIVVLEADLSSSMATNNLEK
                     DFGDRYVNVGIMEAEMVGLAAGLSIQGFRPYLHTFGPFASRRVFDQLFISLGYAQLDA
                     TVIGSDAGVTAEMNGGTHMPFEEIGLLRLIPKSIIFEATDDIQFREILNQTLDLKGLK
                     YIRTIRKAPVPVYQGGEDFSKGYIELRHGEDLVIVASGIMVAPSIRVADELSKLGYSV
                     GVIDLFRIKPIPEQIKTMLSGKTIFTVENHNQIGGIGSALCELFSDDGITKIHRMGVQ
                     ERFGQVGKMDYLLNEYGLSESNIKEKVLEIYNAR"
     gene            complement(7339..8196)
                     /locus_tag="VQU30_001709"
     CDS             complement(7339..8196)
                     /locus_tag="VQU30_001709"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transketolase"
                     /protein_id="HET2447776.1"
                     /translation="MILSKNREDGLRKFATNIRLNTLRTLNHLGFGHYGGSLSIVEVL
                     AVLYGEIMPMTPEIFAARDRDYFILSKGHGGPALYSTLYLNGFFDKEFLYSLNTNGTK
                     LPSHPDRNLTPGIDMTTGSLGQGISVATGLAYGQRIRKSPFYTYAIVGDGELNEGQCW
                     EAIQFASHQQLSNLIVFVDDNKKQLDGFTKDICNPGDFVEKFSAFGFESIRVKGSDIR
                     EIYEGIVQLKQSNNSSPKCIVLDTIKGQGVQELEEMKSNHHLRPTVEEKQMLTSVVER
                     LSQELEETE"
     gene            complement(8200..9546)
                     /locus_tag="VQU30_001710"
     CDS             complement(8200..9546)
                     /locus_tag="VQU30_001710"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000975284.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS ascorbate transporter subunit IIC"
                     /protein_id="HET2447777.1"
                     /translation="MMKFILDIVSTPAILVALIAILGLVLQKKKLPDIIKGGIKTFVG
                     FLVVSGGAGIVQNSLNPFGTMFEHAFHLSGVVPNNEAIVAVALTTYGSATAMIMFAGM
                     VFNILIARFTRFKYIFLTGHHTLYMACMIAVILSVAGFTSLPLILLGGLALGIIMSIS
                     PAFVQKYMVQLTGNDKVALGHFSSLGYWLSGFTGSLIGDKSKSTEDIKFPKSLAFLRD
                     STVSITLSMAVIYIIVAIFAGSEYIEKEISSGTSGLVYALQLAGQFAAGVFVILAGVR
                     LILGEIVPAFKGISERLVPNSKPALDCPIVYTYAPNAVLIGFISSFVGGLVSMVIMIA
                     SGTVVILPGVVPHFFCGATAGVIGNASGGVRGATIGAFLQGILISFLPVFLMPVLGGL
                     GFQGSTFSDADFGLSGIILGMLNQFGSQAGIVIGLVLILAVMFGVSFIKKPSATEE"
     gene            complement(9559..9843)
                     /locus_tag="VQU30_001711"
     CDS             complement(9559..9843)
                     /locus_tag="VQU30_001711"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008089859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HET2447778.1"
                     /translation="MLKIGTACGSGLGSSFMVQMNIESVLSDLNVSDVEVEHYDLGGA
                     DPNAADIWIVGRDLADSASHLGDVRILNSIIDMDELRELITKLCEEKGLI"
     gene            complement(9847..11877)
                     /locus_tag="VQU30_001712"
     CDS             complement(9847..11877)
                     /locus_tag="VQU30_001712"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000460919.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BglG family transcription antiterminator"
                     /protein_id="HET2447779.1"
                     /translation="MFDYRALVILMTLMDHCELSLYELSVKVSLPIKEVKEGIDYLVP
                     YLANKGIVLDKKQGRYSLSNRTKQSLTDIIKSDELVLPKSTRLALIYLYTFCRLDFIS
                     NSHYQDFLKVSKNTTLSDIQSLRKIMLDNDLELGYSRAKGYTLHGSEWNKHRLAFQMV
                     SELLESSIGIWGLDYVLSSWGYSLTYDLIDQVVKDYYEKLQLVPIVNQLKVYLFGLVF
                     ILCRYQRDVERVCLSETLVSPVIQDITTILLDTVVDLGIIDTVFSEDDYRYITVLLSS
                     CFEGEVDVAPVYFNQLTEAIISRMEDISLLHFKQREGLRENLRRHLIPAYYRLKFGLP
                     SSNEYVLHVKEHYPDLFELVKDSLMPLMDAIDNPIPDSETAYFVIHFGGYLKKADTLP
                     QKWYKAAIICPNGVSSSLMLKENLLALFPQIEFIGTSKIDDLQVKASSDYDMVFSTIK
                     VETEKPNYLVSVMMTEEQAIQLVELVLKDFPNLEYGDFEIEQILNIVKRYGIITQELE
                     LRLALKNYLYQKNDRKEIVPVLEQLITKETYQVSSQKLGWKEAIRLAAKPLLDQDKIT
                     ENYPEAMIQKVEEFGPFINLGKGVAIPHARPDEGVNEIGMSMLVLEEPIYLLDNPEQE
                     VRLLICIAAIDNESHLKALSHLTTILRDKNHVQTLISSKNYDDIKMIIKQED"
     gene            12069..13076
                     /locus_tag="VQU30_001713"
     CDS             12069..13076
                     /locus_tag="VQU30_001713"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000136853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SPFH domain-containing protein"
                     /protein_id="HET2447780.1"
                     /translation="MTEKLINSKPNGVFALILIELTIVLGIFIFIMGVGSENIFGIII
                     GPLLIVIAGLAHAGLKVVKPQEALVLTLFGNYTGTIKEPGFYFVNPFSVAVNPANHTR
                     LGQSGDVSTKSPFLGAKSSNDNDVNLEIGKKQISLKVMTLSNSRQKINDCLGNPVEIG
                     IAVTWRVVDTAKAVFNVDNYKEYLSLQCDSALRNIVRIYPYDVSPNVDTTGDGQADEG
                     SLRGSSEIVANRIREEIQSRVEDAGLEILEARITYLAYAPEIAAVMLQRQQASAIIDA
                     RKMIVDGAVGMVEMALERLNEGELVELDEERKAAMVSNLLVVLCGNHDAQPIVNTGSL
                     Y"
     gene            13079..13279
                     /locus_tag="VQU30_001714"
     CDS             13079..13279
                     /locus_tag="VQU30_001714"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399403.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS ascorbate transporter subunit IIC"
                     /protein_id="HET2447781.1"
                     /translation="MAEAKKKQIPLRLSTKLYAALASWAEDDFRSVNGQIEYLLTECV
                     KQRKKDGKYVSETIDEPFEIDI"
     gene            13431..13613
                     /gene="rpmF"
                     /locus_tag="VQU30_001715"
     CDS             13431..13613
                     /gene="rpmF"
                     /locus_tag="VQU30_001715"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000290417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L32"
                     /protein_id="HET2447782.1"
                     /translation="MAVPARRTSKAKKNKRRTHYKVTAPSVNFDETTGDYSRSHRVSL
                     KGYYKGRKITKAASAE"
     gene            13629..13778
                     /gene="rpmG"
                     /locus_tag="VQU30_001716"
     CDS             13629..13778
                     /gene="rpmG"
                     /locus_tag="VQU30_001716"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001265622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L33"
                     /protein_id="HET2447783.1"
                     /translation="MRVNITLEHKESGERLYLTSKNKRNTPDRLQLKKYSPKLRKHVV
                     FTEVK"
     gene            complement(14270..>14416)
                     /locus_tag="VQU30_001717"
     CDS             complement(14270..>14416)
                     /locus_tag="VQU30_001717"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000753868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase family
                     protein"
                     /protein_id="HET2447784.1"
                     /translation="YLNESGSMATGWVTVSGKWYYTYNSGDLLVNTTTPDGYRVNANG
                     EWVG"
BASE COUNT         4645 a         3043 c         2488 g         4240 t
ORIGIN      
        1 ctttgatttt tattgagtat aaaatcctag tttttcaaag atttctgaga agttttggct
       61 gattgtctca agtgacactt gcacttcttc tcgggtttgg ttgttcttga ccgtcacttg
      121 tccgctttcg acttcgctct ctcctagggt gatgagggtc ttagccgcaa agacatcggc
      181 tgacttgaac tgagctttta gtttacggtt gaggtaatca cgctctgctt tgaaaccttg
      241 ttggcgaaga gcctgtacca attccaaggc cttgatattt gccccttcgc ccaagactgc
      301 gatatagaca tctagggcgt tttcgatagg gagggtcaca ccttgctttt caaggatgag
      361 aagcaggcgc tctacaccaa gtccaaaacc aaatccagca gtttcagggc ctccaaagta
      421 agcaaccaaa ccatcgtagc gaccacccgc acagacggtc aggtcattgc cctcaatctc
      481 tgtgataaac tcgaaaatgg tgtggttgta gtagtccaga ccacgcacca tattggtatc
      541 gatgatgtaa tctactccaa gattttccaa catctgacgc acagcatcaa aatgagcttg
      601 gctttcttca tcaagaaagt ccaagataga cggcgcattc tctactgcca ccttgtcttc
      661 tttttcctta gagtccaaga cacgaagagg attttcctcc aagcgacgtt ggctatcctt
      721 agacaaggtc tccttgagcg gtgtcaaata gtcaatcaag gcttggcggt aggctgcacg
      781 gctctcagga tttccaagag tgttgaggtg caatttgaca ccttgaatac cgatttcctt
      841 caaaaaatgg gctgccatag cgattgtttc cacatcggta gctggattgc tagagccaaa
      901 acactcaaca ccaatctggt ggaattggcg caagcgccct gcctgtggac gctcataacg
      961 gaacataggt cccatgtagt agaacttgct tggcttttgc acttctgggg cgaaaagttt
     1021 attttccaca taggaacgga caacgggtgc agttccttct ggacggaggg taatatgacg
     1081 gtcacccttg tcataaaaat cgtacatttc cttggttacg atatccgttg tatctccgac
     1141 agagcgactg ataacctcgt aatgctcaaa aataggcgtg cgcacttctg catagttgta
     1201 gcgtttgaaa atctcacggg caaagccctc aacgtactgc cacttagcag actcagcagg
     1261 taaaatatcc tgcgttcctt ttggtttttg taatttcata gggaatcctc tttaaactta
     1321 atagtcttat tttaccataa atagagggat taaaacagta agaaaaaaat taggatttag
     1381 atatcatttt tgagattaag aattgtcaaa aaaatagcta gcaaggaaag accaacaaat
     1441 agcatccaag tcaactgtat attccatacg gctactagtg aaaaacaagc tgttcccaca
     1501 ggtatggata aggtaaacaa tagacctaaa aaattactag tacgagctag aacctctgga
     1561 gctagatttt tcatgagcat ggcactaatc tttggttgaa ctttaccaga cacatacaga
     1621 gtaaagaaga gaaatagcaa accaagcacg acttgattga ataaattagc caaaccaact
     1681 agactaagtc ctacggtctc ccacatcatc aatctaggca aggactgctt cccaaaataa
     1741 tcattgcccg taaggctact gatgatgact gatactaaaa cacagaattg attgataaat
     1801 agtgcctctg tataagaaaa attcaagaga gaatggctca aaaagaagat attataaatt
     1861 ccacccaaag cgccacccaa ggaattaata agcaagacag caaagagcat aaaaccaaag
     1921 tttttctgtc cacttttaag aaaaacgaga cgtaaatttc ggtaaattgt taggaactgg
     1981 tctttgatag aaagcttctc attttttaag ttttcaccat cagcagatga cattgacagg
     2041 ctcaatttgc tttttcctaa aaagaggata gtggctgata ctaggaaaaa gcaggcattg
     2101 attcccgcaa cgagagaaaa attgttgacc gatagagcta agagccagac tccgaaagct
     2161 tgaccaccaa tagctgaaat ataggtgatg aactgtgaaa aagaataagc ctccatcaga
     2221 tcatcttcag ctactttttc cttaataaga ggcatacgca ggccacctgc aaaatcactg
     2281 atgatatcac taatgacatt gatcaaacac aggctagaaa aggcaaagag actagcttgc
     2341 tgaacaacta gggctgctag aaaaaataga accgcctgaa acaaaccgct atagaccatc
     2401 catttgacct tgtccctcgt gtaatctgcc cgaatccctg caaaaactgt aaagagggtc
     2461 ggaagaatca tgacaatatt cgccatagca acagcaaaag atgcttgtga caaggtcgat
     2521 gcatagacga taaagaccag gttgaaaatc gaaacaccaa aagcattgaa gaagcgtgat
     2581 aaagtcaaaa ttctataagc tggatttcta aacaatagtt tcatagataa tctccctcct
     2641 tgttctaagt tctacatcaa gaatagcttt agtatagcac ttatgaattt gcgaaacgat
     2701 tcttttgaat atatgcaaca aacaaaatga gcaaaaaaac gatagaactt ttgtaatgac
     2761 ctgagagagg gcaacagttc tatcgcttca aattttttct tggtttgcag atattcaaga
     2821 atcgggagtt tttctatagt attcggcaga tttattacag ccaagcatct caaaaatacg
     2881 gacagcatcc tccatctttt tctggccttc cttgactcta ccttgcttgc tatcaaggag
     2941 accttctgcc cacagataaa caattcggaa ataggtctca ttttccttgt agaaatgctc
     3001 ttcgataaca cgtttaaaat aataggcatt ggtaaattct tcacactcaa tactagctaa
     3061 aaagccattc aatagtatag tatgaaaaag gtttcgattg ccagacattt ccattagaaa
     3121 atcggattta cgtaccattt ctcgtacata tctagtaaaa agagaaacag ataaaaatgg
     3181 agaactgact gaaaataaat tgagttcata gattccccag atctcggtag aaaacaaata
     3241 atcatgaagg acttttcctt cctctgctgt taagtctacc ctttcatcta tgctcttcat
     3301 ataagacttg ataataatgg catttagaat atgtttctgt ttgttgtgag aatgggcatg
     3361 cttttatact ccctgcgata taagtcctca agaggtgcta tattctttgg ttccaagaca
     3421 tctgtaattt cttttctcaa ctcagaatct gtatcatact ggaaacctct tgccagaaag
     3481 aggatctcct ccacactggc agatatattt tccagagcaa atagaaactt ttccaccgaa
     3541 agctcactct gacctgtttc aaaacgggac aacatagacg gcgaaaattg tcctccggtt
     3601 gcttgtctca gtgagatatt tcttgactct cgtaattgtc taaagacttt tccaatctgc
     3661 tccatagact tccccttgat tccgtatttt cttcatttta tcatattttt cagaaaattc
     3721 atcaaaaact tgccaaattg tcagaattat gagaaaatag aggatattta tcacgtggag
     3781 ggactgctat gagagacgat atcaaaatca atgaccgtgc tttggccttg caagaccaaa
     3841 ttatcgaaaa actagagaaa gtttttgata cagatgtgga attggatgtt tacaatctag
     3901 gtctgattta tgaaatcaat ctggatgaaa cggggctctg caagattgtc atgaccttca
     3961 ccgatactgc ctgtgattgc gccgaaagcc tgcctattga aatcgtggca ggtctgaaac
     4021 aaatcgaggg tatcaaagat atcaaggttg aagttacctg gtcgcctgct tggaaaatca
     4081 cacgaatcag tcgctatggc cgtattgccc ttggactacc acctcgttaa gcagaccaat
     4141 cacttttaaa gatgaaaaaa gcaagccgaa aatggcttgc tttttgatac tcaatgaaaa
     4201 tcaaagggca aactagaaaa ctagccgcag gttgctcaaa acactgtttt gaagttatgg
     4261 atagaactga cgaagtcagc tcaaaacact gttttgaggt tgtggataga actgacgaag
     4321 tcagctcaaa acactgtttt gaggttgtgg atagaactga cgaagtcagc ccaaaacact
     4381 gttttgaggt tgtggataga actgacgaag tcagtaacca tacctacggc aaggcgacgt
     4441 tgacgtgatt tgaagagatt ttcgagtatg agtttatttt ttacctgact tgtccatatt
     4501 ccagaagtct gtcacggctc cgcgtgaagc agatgatacg atgtgggcat atttaccgag
     4561 gacaccacgg ctgtaaagtg gtggcaaggt tgtttctgcc ttgcgttttt caagttcttc
     4621 ttcggatacg gccatagaaa tttctttggt atcttggtca accgtaacga tatcgccggt
     4681 acggagatag gcaattggtc caccatcctg agcttcagga gcgatatgtc caacaaccag
     4741 accataagta ccaccagaga aacgtccgtc cgtcaagagg gccaccttat ctccctgacc
     4801 tttaccaaca atcattgaag aaagtgatag catctcaggc ataccaggac cacctttagg
     4861 tccaacaaaa cgaacaacga ctacatcgcc atcaacgatt tcatctgtca gaacggcctg
     4921 aatcgcatct tcttctgagt caaagacctt agctggccca acgtgacgac gcactttaac
     4981 acctgatacc ttggcaactg caccgtcagg agcaaggttc ccgttcaaga tgataagcgg
     5041 accatccgca cgttttggat tttcaagtgg catgataact ttttggcctg gagtcaagtc
     5101 tgcaaagtca gccaagtttt cagctacagt cttaccagta catgtgatgc gatctccgtg
     5161 aaggaaacca tttgccaaca aatacttcat aaccgcaggg acaccaccga cttcgtagag
     5221 gtcttggaag acatactgac cagatggttt caagtcggcc aagtgaggca cacgttcttg
     5281 aatcgtattg aagtcctcaa gtgacaagtc aacatttgcg gcatgggcaa tggcgagcaa
     5341 gtgaagagtg gcgtttgtag aaccaccgag agccatcgtt acagtgatag catcttcaaa
     5401 ggcttcacga gtcaagatat ctgatggttt gagaccaagt tccaacatct taacaacagc
     5461 acgtcctgct gcttcgatat cttctttctt atcagctgat tcagctgggt gagaggatga
     5521 ccctggcaaa ctcatcccta gaacttcgat agcagttgcc atggtattag cagtatacat
     5581 accaccacaa ccaccagggc cagggcaggc attacattca agacgtttca cgtcctcagc
     5641 tgtcatgtca ccgtggttcc attttccgat accttcaaag acagaaacca agtcgatatc
     5701 tttaccatca agatttcccg gtgcaatagt tccaccatag gcgaaaatag ctgggatatc
     5761 catattagca atagcaatca tagatccagg catgttcttg tcacagccac cgatagcgac
     5821 gaaggcatcc acgttgtgac cactcatagc cgcctcgatg gagtccgcga tgatgtcacg
     5881 agatgttaga gagaaacgca taccaggcgt tcccatagcg atcccgtccg ctacggtaat
     5941 ggttccaaac tgtacaggcc aagcgcctgc agatttgaca ccttctttag ccagtttccc
     6001 gaaatcatgc aagtgaatgt tacatggtgt attttccgcc caagtcgaaa tcactcccac
     6061 aatcgatgtt tcaaagtcct tatctgtcat accagtcgca cgaagcatag cacggttagg
     6121 tgatttaacc atgctgtcat aaatgctact gcggtgacgt ttatctaatt cagtcatctt
     6181 atccctccca tttcagtttt tactattata gcacaatttt cgcatgaaga acagaataaa
     6241 attcttgaat tttcagaaaa ttctatacac atgtgaaata tttaaaatta aaaacaacaa
     6301 agcggattag tgcactttct gatgaccaga atatgctttt taatccgctt tctttaaata
     6361 acgtactgta atttttacag aaattctttc aaataagtgt atttaacatc tatcttgcat
     6421 tataaatttc tagaaccttc tcttttatat tcgattcact caaaccatac tcattaagaa
     6481 gataatccat tttccctact tgaccgaatc tttcttgaac acccatccga tgaatttttg
     6541 ttattccatc atcagagaat aattcacata aagcactgcc aattccacct atctgattgt
     6601 ggttttctac agtaaatata gtttttccac ttaacattgt ttttatctgt tctggtatcg
     6661 gtttgattct aaataaatct atcacaccta ctgaataacc taatttagac agttcatctg
     6721 caactcgaat acttggagca accattatgc cagaagcaac gattacaaga tcttcaccat
     6781 gccttaactc aatgtagcct ttagaaaaat cttctccacc ttgatacaca ggaactggag
     6841 cttttctaat tgttcgaata tattttagtc cttttaagtc taatgtctgg ttcaatattt
     6901 cacgaaattg gatatcatca gttgcttcga aaatgattga tttaggaatt aaacgtaaca
     6961 atccaatttc ttcaaatggc atatgtgttc caccattcat ctctgccgtt actcctgcat
     7021 ctgatccaat cacagtggca tccaattgtg cgtatccaag agaaataaat aattgatcaa
     7081 atactcttcg tgaagcaaaa ggaccaaatg tatgaagata aggtctaaac ccctgaatag
     7141 acaagcctgc tgcaaggccg accatttctg cttccataat cccaacattc acataacggt
     7201 ctccaaagtc cttttcaaga ttattagtag ccatcgaact tgacaaatcg gcttctaaga
     7261 ctactatatc agaatcactt tgattagcct ctaaaaggaa gtctctatat acatgccgta
     7321 attctttcgt acttctcatc attctgtttc ctccaattcc tgacttaatc tttctacaac
     7381 tgaagttaac atttgtttct cctctacagt agggcgaaga tgatgattgg atttcatttc
     7441 ttccagctct tgaacccctt gacctttaat agtatctaat acaatgcact taggtgatga
     7501 attatttgac tgttttaatt ggacaatccc ttcataaatt tctctaatat ctgaaccctt
     7561 gaccctaatg gattcaaatc caaatgctga aaatttttct acgaaatcac ctggattaca
     7621 aatatccttt gtaaaaccat ctaattgttt tttgttatca tcaacaaata caattaagtt
     7681 ggataactgt tgatgagaag caaactgtat agcctcccaa cattgtccct catttaactc
     7741 accatctcca acaatagcgt aagtataaaa gggactcttt cttattctct gaccatatgc
     7801 aagtccagtt gcaacactaa ttccttgtcc taaagagccc gttgtcatat ctatgcctgg
     7861 cgttagattt ctatcaggat gagacggtaa tttggttcca tttgtattta aagaatataa
     7921 gaattctttg tcaaagaaac cattcaaata gagtgtactg tatagagctg gtcctccgtg
     7981 accttttgat aatatgaaat aatctctatc tcgtgctgca aatatttctg gagtcattgg
     8041 cattatttca ccataaagca ccgctaaaac ttctacgata gacagacttc ctccgtaatg
     8101 tccgaatcca agatgattca atgttctaag agtatttaat cggatgttag tcgcaaattt
     8161 tcttaaccca tcttctctat ttttacttaa aatcatccct tattcctccg ttgcagatgg
     8221 ctttttaata aaggatactc caaacataac tgctagaata agaacaagac caatcacaat
     8281 gcctgcttgt gagccaaatt gatttaacat tcctaaaata attcctgata gaccaaaatc
     8341 tgcatctgag aaagttgatc cttggaaacc aagtcctccc aaaactggca ttaaaaagac
     8401 tggaagaaaa ctgattaaaa taccttgtaa aaatgctcca atagtggctc cacgaacacc
     8461 accagatgca ttcccaatga cacctgcagt cgctccacag aagaaatgag gcacaacacc
     8521 tggtaagata acaaccgttc ctgaagcaat cataattacc atacttacta aaccaccaac
     8581 aaaactagag ataaatccaa ttagaactgc attgggtgca taagtataaa caatcggaca
     8641 atccaaagca ggttttgaat taggtacaag acgctctgaa atacctttaa aggctggaac
     8701 aatttcgccc aaaataaggc gaacacctgc taaaataaca aatacccctg ctgcaaattg
     8761 acctgctaat tgtaaagcat aaactagacc acttgtacca ctactgattt ctttttctat
     8821 atattctgac cctgcaaaga tagctacaat aatgtaaata actgccatgg ataaagtaat
     8881 actaacagta ctatcacgta aaaaagctaa actctttgga aatttaatgt cctctgttga
     8941 ttttgatttg tcaccgataa ggctaccagt aaaaccactc aaccaatatc ccaaagaact
     9001 gaaatgacct aaagctacct tgtcatttcc agttaattga accatatatt tttgcacaaa
     9061 tgctggggaa atactcataa taataccgag tgctaatcct cctagtaaga tgagaggcaa
     9121 gctagtaaag ccagcaactg ataaaatgac cgcaatcata catgccatat atagagtgtg
     9181 gtgccctgtt aaaaaaatat atttaaatcg agtaaaacga gcgattaaga tattgaacac
     9241 catgcctgca aacataatca ttgcagtagc tgagccatat gttgttaaag ctacagctac
     9301 aattgcttca ttattcggca caacgccaga taaatgaaaa gcatgctcaa acatggtacc
     9361 aaatggattt aaagaatttt gtacaattcc tgcaccacca gatacaacta agaaaccaac
     9421 aaaggtctta attccacctt taataatatc aggtaatttc ttcttctgaa gaactaatcc
     9481 taagattgca attaaagcta ctaaaatagc tggtgtacta acaatatcca atatgaactt
     9541 catcatgacg ctagcctcct atataagtcc tttttcttca caaagtttag taattaattc
     9601 tcgtagttca tccatatcaa taatactatt taagatacga acatctccaa gatgactagc
     9661 tgaatcagct agatcacgac caacaatcca aatatcagct gcatttggat ctgctccacc
     9721 taaatcataa tgttcaactt ctacatccga aacattcaaa tcactcaata cagattcaat
     9781 attcatctgt accataaaac ttgaacctaa tcctgaacca caagctgtac caatttttaa
     9841 cattatctaa tcctcctgtt taattatcat tttaatgtca tcatagtttt ttgatgatat
     9901 taaagtttga acatgatttt tatctcttaa aattgttgtt aaatgtgaca aagcctttaa
     9961 atgactctca ttatcaatgg ctgcaataca aatcaacaat cttacctctt gttctggatt
    10021 atccaataaa taaatcggtt cttccaaaac taacattgac attcctattt cattcacacc
    10081 ttcatctggc cgagcgtgag gaattgctac tcccttccct aaattaataa aaggtccaaa
    10141 ctcttctact ttttgaatca ttgcctcagg gtagttctca gttatcttat cttgatccaa
    10201 aagcggttta gctgctaaac gaatcgcctc cttccatcct aatttttgcg aactaacctg
    10261 ataggtttct ttggtaataa gttgttctag cactggtaca atttcctttc tatcattttt
    10321 ttggtaaaga taattcttta acgccaatct taattccaat tcttgtgtaa taattccata
    10381 tcttttgaca atattcagga tttgttcaat ctcaaaatct ccatactcta aattcggaaa
    10441 atcttttaac actagttcta ctagttgtat tgcttgctct tcagtcatca taaccgaaac
    10501 tagataattt ggcttttctg tctccacctt tatggtagaa aaaaccatat catagtcact
    10561 actagctttc acctgtaaat catcaatctt tgaggttcct ataaactcaa tttgaggaaa
    10621 taatgctaat agattctctt ttaacatcaa tgaagaacta acaccattag gacaaatgat
    10681 tgctgcttta taccattttt gaggcaaagt atctgctttc tttaaataac ctccgaaatg
    10741 gataacaaaa tatgctgttt cactatcagg tatgggattg tcaatagcgt ccatcaaggg
    10801 catcaaagaa tctttgacta attcaaataa atcaggataa tgttctttaa catgcaatac
    10861 atattcattt gaactaggta ggccgaactt taatctatag taagccggta taaggtggcg
    10921 gcgaagattt tctctcaatc cttccctttg tttaaaatgt aacaaagaaa tatcttccat
    10981 tctacttata atagcctctg ttaattgatt aaagtaaacc ggagcaacat ctacttcacc
    11041 ttcaaagcaa cttgataata aaacggtgat atagcgataa tcatcctcag aaaacaccgt
    11101 atctataatt cccaaatcaa ccactgtatc caataaaata gtggttatat cttgaataac
    11161 aggagatact aatgtctctg aaagacatac tctttcaaca tccctttgat acctacacag
    11221 aatgaatact aaaccgaaaa ggtaaacttt taattgatta acaataggta ctagctgtag
    11281 cttctcataa taatctttaa ctacctgatc aatcaaatca taagttaatg aataccccca
    11341 actggataaa acataatcca aaccccaaat ccctatggag gattccagca actcactaac
    11401 catttgaaaa gctaagcggt gcttattcca ctctgaaccg tgtaaagtat aaccttttgc
    11461 tctactgtac cctagctcca aatcattatc taacataatc tttcttaatg attgaatatc
    11521 agataaggtt gtattcttac ttactttcaa aaagtcttgg taatgactat tcgatataaa
    11581 atctaatcgg caaaaagtgt aaagatagat taaagctaag cgagtcgact ttggtaaaac
    11641 caattcatcc gacttaataa tatctgtcaa agactgcttc gtacgatttg ataaactata
    11701 gcgaccttgc tttttatcca gcactatccc tttattagct agataaggca ctaaataatc
    11761 tattccttct ttgacttcct ttataggtaa gctcacctta acagataatt catataatga
    11821 tagctcacaa tgatccatca aagtcatcaa aataactagt gctctataat caaacatttc
    11881 tcttcctttc taactacaat tatagtgtaa aaattataag aataaaagag tatttgagca
    11941 caatataatc tcacctttta aaagaaatta ttgggctgaa agtttttagt gattattttt
    12001 caactttcta ttgactttat aaattaaagt gatatcattt agatatcaaa taacaggagg
    12061 tcattcttat gactgaaaaa ctaatcaatt caaaaccaaa tggtgtattc gcattgattc
    12121 tcattgagtt gacaatcgta cttggtatct ttatatttat aatgggggtt ggttcggaaa
    12181 acatttttgg aattattatc ggacctttac taatcgtaat tgcaggtcta gctcatgctg
    12241 gtttaaaagt tgtcaaacct caagaagctc tggttctgac actctttggt aactatacag
    12301 gtaccatcaa agaacctggc ttttactttg tcaatccctt cagcgtagca gtcaaccctg
    12361 caaaccacac tcgacttgga caaagtggtg atgttagcac aaaatctcct tttttaggag
    12421 ctaaatcatc aaatgacaat gatgtaaatc ttgaaattgg caagaaacag atttccctca
    12481 aagtcatgac cttgagcaat tctcgtcaaa aaatcaatga ttgcttagga aaccctgtag
    12541 aaatcggtat cgcggtaact tggagagttg tcgataccgc taaggcagtc ttcaacgttg
    12601 ataactacaa agaatatctt tcattgcaat gtgatagcgc cctccgtaat attgtccgca
    12661 tctatcctta cgatgtgtct cctaatgtgg atactacggg tgatgggcaa gcagatgaag
    12721 gtagtctccg tggctctagc gaaattgttg ctaaccgtat tcgtgaagaa atccaaagtc
    12781 gtgttgagga tgctggcttg gaaatccttg aagcacgtat cacttaccta gcttatgctc
    12841 cagaaattgc tgccgttatg cttcaacgcc aacaagcatc tgccattatt gatgcacgga
    12901 agatgattgt agatggtgct gtaggaatgg ttgaaatggc actagaacgg ctcaatgaag
    12961 gggaattggt agaacttgac gaagaacgaa aagctgccat ggtttcaaat ctccttgtcg
    13021 ttctttgtgg caatcatgat gcacaaccaa ttgtcaacac aggaagcctt tactaaagat
    13081 ggctgaagct aaaaaaaagc agatccccct tcgactctca acaaagttat acgctgcact
    13141 cgcatcatgg gcagaagacg actttcgttc agtcaatggg caaatcgaat atctcctcac
    13201 agagtgtgtc aagcaacgga agaaagacgg aaaatacgta tcagaaacca ttgacgaacc
    13261 atttgagatt gatatttaac accttctcct gtctgccgtg tcggatagga gaattttttc
    13321 atcttttttt gtcaagtaac tttactttac aaaaaaaatg tgttatccta gtatggttga
    13381 tgaaaatcag tagattgaat cgaatataaa tacctaaagg agaaatcaaa atggcagtac
    13441 ctgcacgtcg cacttcaaaa gcgaagaaaa acaaacgtcg tacacactac aaagtaacag
    13501 ctccatctgt aaactttgac gaaactactg gagattactc acgttctcac cgtgtatcac
    13561 ttaaaggata ctacaaagga cgtaaaatca ctaaagctgc atcagctgaa taatagaagg
    13621 gagataccat gcgcgtaaat attacacttg aacacaaaga atctggtgaa cgcttgtacc
    13681 ttacttctaa aaacaaacgt aacactccag accgccttca attgaagaaa tactcaccaa
    13741 aacttcgcaa acacgttgtg tttacagagg ttaaataagc attcaatacg aatcaataca
    13801 gaagaaaaac gcttgatcag cgttttttct ttttgttaat ttcactacat tgtaagggaa
    13861 atcattcgaa tgactacatt tttcactacc ttttttgaaa taagaatacg gattcggaca
    13921 attaaaagca agaggaactc aaatgtaagt tggggttcct tttttgtata tttttcaaat
    13981 aacgcctcta cactatttgt agcaaattca ccaactacag ttgtatctta gttaaaataa
    14041 gttagaatat gtaagtgagt accagatata ccaagacatc gtcaccatct aaggtatatt
    14101 caaaatacaa aagttgacca actagatttc tgaatatcct tatatatcca ttcttaaaat
    14161 tggtttaaat agcgtagtct tttaaactag ttttgagaat ccaaaaaatc ttcctacata
    14221 tgtaagaaga ttttttagtt cagaatgatt agatttagct aatggatacc tatcctaccc
    14281 actcaccgtt agcattgact cgatagccat cgggtgtagt cgtgtttact aataaatctc
    14341 ctgaattata ggtatagtac catttaccag aaactgtaac ccaaccagta gccattgaac
    14401 ctgattcatt taagta
//
LOCUS       DAVBBO010000054        14254 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ST1
            SAMEA2066453-rid20184263.denovo.054, whole genome shotgun sequence.
ACCESSION   DAVBBO010000054 DAVBBO010000000
VERSION     DAVBBO010000054.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2066453
            Sequence Read Archive: ERR351777
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 14254)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14254)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980402.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980402.1
            Genome Coverage       :: 176x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:17:33
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,141
            CDSs (total)                      :: 2,104
            Genes (coding)                    :: 1,953
            CDSs (with protein)               :: 1,953
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 16S)
            partial rRNAs                     :: 1 (23S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 151
            CDSs (without protein)            :: 151
            Pseudo Genes (ambiguous residues) :: 0 of 151
            Pseudo Genes (frameshifted)       :: 73 of 151
            Pseudo Genes (incomplete)         :: 76 of 151
            Pseudo Genes (internal stop)      :: 40 of 151
            Pseudo Genes (multiple problems)  :: 32 of 151
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14254
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2066453-rid20184263.denovo.054"
                     /strain="ST1"
                     /db_xref="taxon:1313"
     gene            3..350
                     /locus_tag="VQU30_001718"
     CDS             3..350
                     /locus_tag="VQU30_001718"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001273322.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2447785.1"
                     /translation="MLRLPYKKQKISHFTVSEDKDICRYIRQQLYYQNLFWMKEQAEA
                     YQKGENILTYGLKEWYPQIRPIVGKFFQIEQDLTSYYQHFYTYYQKNPQNDWQKLYPP
                     AFYQQYFLKNMVE"
     gene            369..2171
                     /gene="pepF"
                     /locus_tag="VQU30_001719"
     CDS             369..2171
                     /gene="pepF"
                     /locus_tag="VQU30_001719"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004252660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligoendopeptidase F"
                     /protein_id="HET2447786.1"
                     /translation="MVLQRNEINEKDTWDLSTIYPTDQAWEEVLKDLTEQLETVAQYE
                     GHLLDSADNLLEITEFSLEMERQMEKLYVYAHMKNDQDTREAKYQEYYAKAMTFYSQL
                     DQAFSFYEPEFMEISEKQYADFLEAQPKLQVYQHYFDKLLQGKDHVLSQREEELLAGA
                     GEIFGSASETFAILDNADIVFPYVLDDDGKEVQLSHGIYTRLMESKKREVRRGAYQAL
                     YATYEQFQHTYAKTLQTNVKVQNYRAKVRNYKSARHAALAANFVPESVYDNLVAAVRK
                     HLPLLHRYLELRSKILGISDLKMYDVYTPLSSVEYSFTYQEALKKAEDALAVLGEDYL
                     SRVKRAFSERWIDVYENQGKRSGAYSGGSYDTNAFMLLNWQDNLDNLFTLVHETGHSM
                     HSSYTRETQPYVYGDYSIFLAEIASTTNENILTEKLLEEVEDDATRFAILNNFLDGFR
                     GTVFRQTQFAEFEHAIHQADQNGEVLTSDFLNKLYADLNQEYYGLSKEDNPEIQYEWA
                     RIPHFYYNYYVYQYSTGFAAASALAEKIVHGSQEDRDRYIDYLKAGKSDYPLNVMRKA
                     GVDMEKEDYLNDAFAVFERRLNEFEALVEKLGLA"
     gene            2173..2886
                     /locus_tag="VQU30_001720"
     CDS             2173..2886
                     /locus_tag="VQU30_001720"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812425.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="O-methyltransferase"
                     /protein_id="HET2447787.1"
                     /translation="MVESYSKNANHNMRRPVVKEEIVDLMRQRQKQVTGFLKELENFA
                     RKENIPIIPHETVAYFRFLMETMQPKNILEIGTAIGFSALLMAEHAPNAKITTIDRNP
                     EMIGFAKENFAQFDSRKQITLLEGDAVDVLSTLTESYDFVFMDSAKSKYIVFLPEILK
                     HLEVGGVVVLDDIFQGGDVAKDIMEVRRGQRTIYRGLQKLFDATLDNPELTATLVPLG
                     DGILMLRKNVADVQLSESE"
     gene            2953..3894
                     /gene="prsA"
                     /locus_tag="VQU30_001721"
     CDS             2953..3894
                     /gene="prsA"
                     /locus_tag="VQU30_001721"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399245.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase PrsA"
                     /protein_id="HET2447788.1"
                     /translation="MKKKLLAGAITLLSVATLAACSKGSEGADLISMKGDVITEHQFY
                     EQVKNNPSAQQVLLNMTIQKVFEKQYGSELDDKEVDDTIAEEKKQYGENYQRVLSQAG
                     MTLETRKAQIRTSKLVELAVKKVAEAELTDEAYKKAFDEYTPDVTAQIIRLNNEDKAK
                     EVLEKAKAEGADFAQLAKDNSTDEKTKENGGEITFDSASTEVPEQVKKAAFALDVDGV
                     SDVITATGTQAYSSQYYIVKLTKKTEKSSNIDDYKEKLKTVILTQKQNDSTFVQSIIG
                     KELQAANIKVKDQAFQNIFTQYIGGGDSSSSSSTSNE"
     gene            complement(4011..4352)
                     /locus_tag="VQU30_001722"
                     /pseudo
     CDS             complement(4011..4352)
                     /locus_tag="VQU30_001722"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611512.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
     gene            4765..4860
                     /locus_tag="VQU30_001723"
                     /pseudo
     CDS             4765..4860
                     /locus_tag="VQU30_001723"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(5113..5733)
                     /locus_tag="VQU30_001724"
     CDS             complement(5113..5733)
                     /locus_tag="VQU30_001724"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000780815.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HET2447789.1"
                     /translation="MKLYFVRHGRTLWNQEGRFQGASGDSPLLPESIETLKRLGQYLK
                     EIPFDQIYSSDLPRAVKSAEIIQSQLYTPCSLEIVPNLREWQLGKLEGLKIATLEAIY
                     PQQIQAFRSNLAQFDTRMFGAESLYSTTQRTIQFIKSLKDSPAERILIVGHGANLTAS
                     LRTLLGYKEPLLRKDGGLANASLTIIETHDFETFTLNTWNDTSYQS"
     gene            complement(5733..6215)
                     /locus_tag="VQU30_001725"
     CDS             complement(5733..6215)
                     /locus_tag="VQU30_001725"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397917.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoacyl-tRNA deacylase"
                     /protein_id="HET2447790.1"
                     /translation="MAKKVKIKKTLVEQILSKAAIPHQGIQINALEGELPQGYERDQI
                     FKTLALLGDKTGPIIGIVPITQHLSEKKLAKISGNKKVSMIPQKDLEKTTGYIHGANN
                     PVGIRQKHNYPIFIDKIALDLDRMIVSAGEVGHSIIVAPQDLASFVKADFVDILEDIK
                     "
     gene            complement(6215..7057)
                     /locus_tag="VQU30_001726"
     CDS             complement(6215..7057)
                     /locus_tag="VQU30_001726"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004256605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF368 domain-containing protein"
                     /protein_id="HET2447791.1"
                     /translation="MLSWLARVIKGIVIALGFILPGISGGVLAAILGIYERMIGFLAH
                     PFKDLKENVLYFIPVAIGMLLGIGLFSYPIEYLLENYQVFVLWSFAGAIIGTVPSLLK
                     ESTRESDRDKIDLAWLWTTFIISGLGLYALNFVVGTLSASFLNFVLAGALLALGVLVP
                     GLSPSNLLLILGLYAPMLTGFKTFDLLGTFFPIGIGAGATLIVFSKLMDYALNNYHSR
                     VYHFIIGIVLSSTLLILIPNAGNAESIQYTGLSLVGYVIIAFFFALGIWLGIWMSQLE
                     DKYK"
     gene            complement(7152..7952)
                     /locus_tag="VQU30_001727"
     CDS             complement(7152..7952)
                     /locus_tag="VQU30_001727"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 25 protein"
                     /protein_id="HET2447792.1"
                     /translation="MRKQIHPLILFSFFGIMMFILIINRPLNDSQSFKTKSNIAQIEA
                     QALKHLDKPIIDLSGWQRPEEINYDALSQNISGAIVRVHSGAQTTKENDASFINGIDK
                     AYKSHITELQKRNVPVAVYAYVAGKSVQEMEKAAEVFYNAASPYSPSYYWLDVEDKTM
                     SNMNEGVENFRAKLASLGAKNIGIYVGVYFMEEHSIDTGKFTSVWIPSYGSDSGFLES
                     SPKTDLDYDIHQYTSKGKIAGFDHDLDINVISPLKNKEETFRKLFLKP"
     gene            8096..9475
                     /gene="glmU"
                     /locus_tag="VQU30_001728"
     CDS             8096..9475
                     /gene="glmU"
                     /locus_tag="VQU30_001728"
                     /EC_number="2.3.1.157"
                     /EC_number="2.7.7.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000073762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional UDP-N-acetylglucosamine
                     diphosphorylase/glucosamine-1-phosphate
                     N-acetyltransferase GlmU"
                     /protein_id="HET2447793.1"
                     /translation="MSNFAIILAAGKGTRMKSDLPKVLHKVAGISMLEHVFRSVGAIQ
                     PEKTVTVVGHKAELVEEVLAGQTEFVTQSEQLGTGHAVMMTEPILEGLSGHTLVIAGD
                     TPLITGESLKNLIDFHINHKNVATILTAETDNPFGYGRIVRNDNAEVLRIVEQKDATD
                     FEKQIKEINTGTYVFDNERLFEALKNINTNNAQGEYYITDVIGIFRETGEKVGAYTLK
                     DFDESLGVNDRVALATAESVMRRRINHKHMVNGVSFVNPEATYIDIDVEIAPEVQIEA
                     NVTLKGQTKIGAETVLTNGTYVVDSTIGAGAVITNSMIEESSVADGVTVGPYAHIRPN
                     SSLGAQVHIGNFVEVKGSSIGENTKAGHLTYIGNCEVGSNVNFGAGTITVNYDGKNKY
                     KTVIGDNVFVGSNSTIIAPVELGDNSLVGAGSTITKDVPADAIAIGRGRQINKDEYAT
                     RLPHHPKNQ"
     gene            9485..10030
                     /locus_tag="VQU30_001729"
     CDS             9485..10030
                     /locus_tag="VQU30_001729"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000393791.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HET2447794.1"
                     /translation="MEFEEKTLSRKEIYQGPIFKLVQDQVELPEGKGTARRDLIFHNG
                     AVCVLAVTDEQKLILVKQYRKAIEAVSYEIPAGKLEVGENTAPVAAALRELEEETAYT
                     GKLELLYDFYSAIGFCNEKLKLYLASDLTKVENPRPQDEDETLEVLEVSLEEAKELIQ
                     SGHICDAKTIMAVQYWELQKK"
     gene            10042..10356
                     /locus_tag="VQU30_001730"
     CDS             10042..10356
                     /locus_tag="VQU30_001730"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000517865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="foldase"
                     /protein_id="HET2447795.1"
                     /translation="MGKSLLTDEMIERANRGEKISGPPLLDDNEETKILPTSSSRFGY
                     ANPKDHGFSQETLKIQVEPSIHKSRRIENTKRNVFNSKLNKILFAVIFLLILLVLAMK
                     LL"
     gene            10373..11065
                     /locus_tag="VQU30_001731"
     CDS             10373..11065
                     /locus_tag="VQU30_001731"
                     /EC_number="3.2.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004261401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5'-methylthioadenosine/adenosylhomocysteine
                     nucleosidase"
                     /protein_id="HET2447796.1"
                     /translation="MKIGIIAAMPEELAYLVQHLDNTQEQVVLGNTYHTGTIASHEVV
                     LVESGIGKVMSAMSVAILADHFQVDALINTGSAGAVAEGIAVGDVVIADKLAYHDVDV
                     TAFGYAYGQMAQQPLYFESDKTFVAQIQESLSQLDQNWHLGLIATGDSFVAGNDKIEA
                     IKSHFPEVLAVEMEGAAIAQAAHALNLPVLVIRAMSDNANHEANIFFDEFIIEAGRRS
                     AQVLLTFLKALD"
     gene            11142..11633
                     /gene="rocS"
                     /locus_tag="VQU30_001732"
     CDS             11142..11633
                     /gene="rocS"
                     /locus_tag="VQU30_001732"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000021242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chromosome segregation protein RocS"
                     /protein_id="HET2447797.1"
                     /translation="MSIEMTVSEIAEVLGLSRQAINNRVKELPEEDTDKNDKGVTVVT
                     RSGLIKLEEIYKKTIFEDEPVSEDVKQRELMEILVDEKNAEILRLYEQLKAKDRQLSE
                     KDEQMRIKDRQIAEKDKQLDQQQQLTLQAMKDQENLKLELDQAKEEVQSTKKGFFARL
                     FGG"
     gene            11731..12321
                     /locus_tag="VQU30_001733"
     CDS             11731..12321
                     /locus_tag="VQU30_001733"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399240.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3'-5' exonuclease"
                     /protein_id="HET2447798.1"
                     /translation="MERLEDYIAFDLEFNQHEGQTHLIQVSAVRFRDGREIDAYDSYV
                     HTSVPLKSFINGLTGITAETLKDAPPVEKVLEEFQEFVGSLLMIGYNAAKSDLPILAE
                     HGLDYSQQYKVDLYDEAFERRSSDLHGIANLKLQTVASFLGFQGQSHNSLEDARMTAR
                     VYESFLESDQARELLETESSLSNNPFGVLDLSQLFD"
     gene            12330..14093
                     /locus_tag="VQU30_001734"
     CDS             12330..14093
                     /locus_tag="VQU30_001734"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000801733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerophosphodiester phosphodiesterase"
                     /protein_id="HET2447799.1"
                     /translation="MKPEKPKKLGLKQIYLNLDKILFLFFLIFMIVEYLWVPFNSWLA
                     SFLLDQTGYLFISYNNVLAILTHSPLISLAFLALIVINLLVAYFQIGLLFIGARHLLY
                     NEKRRLIEYIRKVFHESFGFMKKLTCAKALFIFFYIAMLFPFIRKMLKIYYLNKIVIP
                     EFIQAYLEDKYWMWWLSILLLSLIFLYVSVRLMFALPKIVYDQLTVREAVMFSLEKTK
                     KRVTFYAWNLFYILLKAHLLFYLPLIPLLLAQTLVDDITQRESLILGILNFVVIKNLY
                     YMALTYFLVKFVSFLTGKELDMLPRREKDHIVRWGVMTCASLFFALEGYIYLEAPMVH
                     LPQLISHRGVSNANGIQNTVESLETTAQLKPDLVETDVQETKDGQFVMMHDANLKNLA
                     GINKSPQDLNLEELKGIDIFENGYQTKISSFEDYLSRANELGQKLLIEIKTSKKDSPD
                     MMNRFLARYAAKLKIYGHQIQSLDYHVVEKVRQYDAELPVYFIMPYNSVFPKTRATGY
                     TMEYSTLDEYFVSKLWTTDQKLYVWTVNDSEAISKSLHLGVDGVITDDLEKVQREIEV
                     AQEDPEYTDLLLKKALEFFEF"
BASE COUNT         4485 a         2552 c         2969 g         4248 t
ORIGIN      
        1 aaatattgcg tcttccctat aagaaacaaa aaatatctca ttttacagtt tctgaggaca
       61 aggacatctg tcgctatatc cggcaacaac tttattatca aaatctcttt tggatgaaag
      121 aacaagcaga agcctatcaa aagggagaaa atatcctgac ttatggactg aaagaatggt
      181 atccacaaat tcgaccaata gtgggcaaat ttttccagat tgaacaagac ttgactagct
      241 attatcagca cttttatacc tattaccaaa aaaatcctca aaatgattgg caaaagcttt
      301 atccaccagc cttttatcag caatatttct tgaaaaatat ggtagaatag aaaggatgga
      361 ggaatctaat ggtattacaa agaaatgaaa taaatgaaaa agatacatgg gatctatcaa
      421 cgatctaccc aactgaccag gcttgggaag aagtcttaaa agatttaaca gaacaattgg
      481 agacagtagc ccagtatgaa ggccatctct tggatagtgc ggataaccta ctagaaatca
      541 ctgaattttc tcttgaaatg gaacgccaga tggagaagct ttacgtttat gctcatatga
      601 agaatgacca ggatacacgt gaagctaagt atcaagagta ctatgccaag gccatgacat
      661 tctacagcca gttagaccaa gccttttcat tctatgagcc tgaatttatg gagattagcg
      721 aaaagcagta tgctgacttt ttagaagctc aaccaaagct gcaggtttat caacactatt
      781 ttgacaagct cttgcaaggc aaggatcacg ttctctcaca acgtgaagaa gaattattgg
      841 ctggagctgg agaaatcttt ggttcagcaa gtgaaacctt cgctatcttg gacaatgcgg
      901 atattgtgtt cccttatgtc ctagacgatg atggtaaaga agttcagcta tctcatggga
      961 tttacacacg tttgatggag tctaaaaaac gtgaggttcg ccgtggtgcc tatcaagctc
     1021 tttatgcgac ttacgaacaa ttccaacaca cctatgccaa aaccttgcaa accaatgtta
     1081 aggtgcaaaa ttaccgtgct aaagttcgta actacaagag tgctcgtcat gcagccctcg
     1141 cagcgaattt tgttccagaa agtgtttatg acaatttggt agcagcagtt cgcaagcatt
     1201 tgccactctt acatcgctat cttgagcttc gttcaaaaat cttggggatt tcagatctca
     1261 agatgtacga tgtctacaca ccgctttcat ctgttgaata cagttttacc taccaagaag
     1321 ccttgaaaaa agcagaagat gctttggcag tcttgggtga ggattacttg agccgtgtta
     1381 aacgtgcctt cagcgagcgt tggattgatg tttacgaaaa tcaaggcaag cgttcaggtg
     1441 cctactctgg tggttcttac gataccaatg cctttatgct tctcaactgg caggacaatc
     1501 tggacaatct ctttactctt gttcatgaaa caggtcacag tatgcattca agctatactc
     1561 gtgaaactca gccttatgtt tacggagatt actctatctt tttggctgag attgcctcaa
     1621 ctaccaatga aaatatcttg acggagaaat tattggaaga agtggaagac gacgcaacac
     1681 gctttgctat tctcaataac ttcctagatg gtttccgtgg aacagttttc cgccaaactc
     1741 aatttgctga gtttgaacac gccattcacc aagcagatca aaatggggag gtcttgacaa
     1801 gcgatttcct aaataaactc tacgcagact tgaaccaaga gtattatggt ttgagtaagg
     1861 aagacaatcc tgaaatccaa tacgagtggg ctcgcattcc acacttctac tataactact
     1921 atgtatatca atattcaact ggctttgcgg ccgcctcagc cttggctgaa aaaattgtcc
     1981 atggtagtca agaagaccgt gaccgctata tcgactacct caaggcaggt aagtcggact
     2041 atccacttaa tgtcatgaga aaagctggtg ttgatatgga gaaggaagac tacctcaacg
     2101 atgcctttgc agtctttgaa cgccgtttaa atgagtttga agcccttgtt gaaaaattag
     2161 gattggcata aaatggttga atcgtatagt aagaatgcta accataacat gcgtcgtcct
     2221 gtcgtcaaag aagaaattgt agacttgatg cgtcagcgtc aaaagcaggt cacaggtttc
     2281 ttgaaagaat tggaaaactt tgcccgcaag gaaaatattc ctattattcc ccatgaaacg
     2341 gttgcttatt tccgttttct tatggaaacc atgcagccta aaaatattct ggaaattggg
     2401 acggctatcg gtttttcagc tctcttgatg gctgaacatg cgccaaatgc taagattaca
     2461 actattgatc gtaatccaga aatgattggt tttgccaagg aaaattttgc ccagtttgac
     2521 agtcgcaagc aaatcactct cctagaggga gatgcggtgg atgtcttatc tacactgaca
     2581 gagtcttatg atttcgtctt tatggattct gccaagtcta aatacatcgt ctttctgcca
     2641 gaaatcctca aacatttgga agttggtggt gtggttgtct tggatgatat ttttcaaggt
     2701 ggtgatgttg ccaaggatat tatggaagtc cgtcgtggtc agcgaaccat ttatcgaggc
     2761 cttcaaaaat tatttgatgc aaccttagac aatccagaac tcaccgcaac attagtgcct
     2821 ttaggagatg gtattctcat gcttcgtaaa aatgtagcag atgttcaact gtctgaaagc
     2881 gaatgatttt cagaaaaatt taagaaaaaa tagtaaaata gatagagtaa cacttatctc
     2941 aaaggagtag acatgaagaa aaaattattg gcaggtgcca tcacactatt atcagtagca
     3001 actttagcag cttgttcgaa agggtcagaa ggggcagacc ttatcagcat gaaaggggat
     3061 gtcatcacag aacatcaatt ttatgagcaa gtgaaaaaca acccttcagc ccaacaagtc
     3121 ttgttaaata tgaccatcca aaaagttttt gaaaaacaat atggctcaga gcttgatgat
     3181 aaagaggttg atgatactat tgccgaagaa aaaaaacaat atggcgaaaa ctaccaacgt
     3241 gtcttgtcac aagcaggtat gactcttgaa acacgtaaag ctcaaattcg tacaagtaaa
     3301 ttagttgagt tggcagttaa gaaggtagca gaagctgaat tgacagatga agcctataag
     3361 aaagcctttg atgagtacac tccagatgta acggctcaaa tcatccgtct taataatgaa
     3421 gataaggcca aagaagttct cgaaaaagcc aaggcagaag gtgctgattt tgctcaatta
     3481 gccaaagata attcaactga tgaaaaaaca aaagaaaatg gtggagaaat tacctttgat
     3541 tctgcttcaa cagaagtacc tgagcaagtc aaaaaagccg ctttcgcttt agatgtggat
     3601 ggtgtttctg atgtgattac agcaactggc acacaagcct acagtagcca atattacatt
     3661 gtaaaactca ctaagaaaac agaaaaatca tctaatattg atgactacaa agaaaaatta
     3721 aaaactgtta tcttgactca aaaacaaaat gattcaacat ttgttcaaag cattatcgga
     3781 aaagaattgc aagcagccaa tatcaaggtt aaggaccaag ccttccaaaa tatctttacc
     3841 caatatatcg gtggtggaga ttcaagctca agcagtagta catcaaacga atagtccaaa
     3901 tcaatgagtc agggaaaaaa actcgacttc aggaaaaaat gaagcaaaca ttcccacaat
     3961 aaaacgcata gtacaaggtt tgtactgacc ccaaaagtta gacaattaat ttatctgaag
     4021 gatttagttc tgtattgcac agggctaagt ccttttagtt ttaccttaat tctcttattg
     4081 ttgtaataat caatatagtc tataatggct tgttccaatt gattaagtga tttaaatgtt
     4141 ttctcatagc cataaaacat ttcggatttt aaaatgccaa agaaagattc catcctaccg
     4201 ttgtcttggc tgtttccttt gcgtgacata gatgcttgaa ttcccttact ctctaggaag
     4261 cgatgataag aatcgtgttg gtattgccag ccttggtcac tatggagaat cgtattctcg
     4321 tagtgcttct ctttgaatgc ctgttccaac attaacgatc aatcaattta atcatgtacc
     4381 taatattaga attgtttatc ccaaatttat ttgaaagctt ctctaagcta tatccttgtt
     4441 ttctaagttc atagatctga actttatcat cataagttaa tttcataata aaaacacccc
     4501 aaaagttaga ttttttctgt ctaacttttg gggtgtagtt catgtacacc tgatatgatg
     4561 cgttttataa ttttaaagac tttttgacca gcctcatttt tttaacttga tactcagtga
     4621 aaagcaaaga ttaaactagg aagctagctg taggctgctc aaagaacagc tttgaggttg
     4681 cagataaaac ttgtgaggtc accaacatat ataatgtgaa gctgacgtga cttgaataga
     4741 ttttagaagg gtatgagtct ggaagtttta atggataatg caagattcca tagaatgggt
     4801 aagctagagt tcttatgtga agagtttggg cataaacttt taccttttcc tccctactca
     4861 tcttagtata gaaaagtgaa tctaaaatag tacataactg cttctaaaac attcttataa
     4921 attgatttaa attctcaaat catattattc agttcttatt tcattttgct ctacaatcct
     4981 gttgagaaga cacgtgttca tatcaaaaag gtattggcaa gttgcaatac ctttttacaa
     5041 ggttcttttg tcttattttt gtttcaactg actatatctc ctatggttct agttcagaag
     5101 gctaggctat aattatgatt gataagaagt atcattccaa gtattgagag tgaatgtttc
     5161 aaaatcatgg gtttctataa tggtcaggct ggcatttgct agaccgccat ctttacgaag
     5221 aagtggttct ttatagccta ggagagtacg aagactggca gtaagattgg cgccgtgtcc
     5281 gacaattaga atacgctcag ctggactatc ttttaatgat ttgataaatt ggatggtccg
     5341 ttgagttgta ctatagaggg attcggctcc gaacattcga gtgtcaaatt gagcaagatt
     5401 tgaacgaaaa gcctggattt gttgcgggta aatagcttcc aaggttgcaa ttttcaaacc
     5461 ttctaacttc ccaagttgcc attcacggag attaggaacg atttctaaag aacagggggt
     5521 atagagttga ctttggataa tctcagcaga tttgaccgct cgaggtaaat cacttgaata
     5581 aatctgatca aaaggaattt ccttgagata ctggccaagt cgttttaggg tttcaatgga
     5641 ttcaggaaga agaggagaat caccgctagc accttgaaaa cgaccttctt ggttccagag
     5701 ggtacgaccg tggcggacaa agtagagttt cattacttga tgtcctccaa aatatctaca
     5761 aagtctgcct ttacaaagct agccaagtct tgtggcgcga cgataatgct gtgtccgact
     5821 tcgcctgcag agacaatcat tcgatccaaa tctagagcaa ttttatcgat aaaaatggga
     5881 taattgtgtt tctgacgaat tccgacagga ttattggctc catgaatgta accagttgtt
     5941 ttttctaagt ccttttgtgg aatcatgctc acttttttat tgccagaaat tttagctagt
     6001 ttcttttcag acaagtgctg agtgataggg acaattccga taatcggtcc ggtcttgtct
     6061 cccaaaagcg ccaaggtttt gaaaatctga tctcgttcat aaccttgagg aagctctcct
     6121 tctagggcat tgatttgaat cccctgatga gggatagctg ctttagatag gatttgttcc
     6181 accaatgttt ttttgatttt aacttttttt gccattattt atatttatcc tccaattgac
     6241 tcatccaaat accaagccag attcccagcg caaagaagaa ggcgatgatg acataaccga
     6301 caagtgaaag tcctgtgtat tggatacttt cagcgtttcc tgcatttgga attaagatca
     6361 aaagggtact tgataggacg ataccgatga tgaaatgata gacgcgtgag tggtagttgt
     6421 ttaaggcata atccatcaat tttgaaaaaa cgatgagagt tgcacctgca ccaattccaa
     6481 tcggaaagaa ggttcccaag agatcaaaag ttttaaaacc agtcaacata ggagcataga
     6541 gtcccaaaat caaaagtaag ttcgatgggc tgaggccagg aaccaagacg ccaagggcca
     6601 atagtgcgcc tgctaggacg aagttaagaa agctggcgct taaggttcca acgacaaaat
     6661 ttaaggcata gagtcctaat ccagaaatga taaaggttgt ccataaccaa gctaaatcaa
     6721 tcttgtctcg gtcagattct cgagttgatt ctttgaggag gctaggaact gtaccgataa
     6781 tagctcccgc aaagctccat aatacaaaga cctgataatt ttcaagcagg tattcaatcg
     6841 ggtaggaaaa taagccgatt cccagaagca taccgatggc aactggaata aagtacaaaa
     6901 cattttcttt aaggtcttta aagggatggg ccagaaagcc aatcattcgt tcatagattc
     6961 ctaagattgc tgctagaacc cctccggaaa ttcccggtag gataaatcca agagcaatta
     7021 caatcccttt aataacgcgt gctaaccatg agagcatata tttcctccaa ctatttctat
     7081 ttcaaaaatt ccttactata ttgtatcaca atcagacaca aaaagaaaaa gcaaatgata
     7141 aacaaatgct tttaaggttt taaaaaaagt tttcgaaagg tttcttcttt attttttaag
     7201 ggagagataa cgttgatatc taaatcgtgg tcaaagccgg caatttttcc tttagatgtg
     7261 tattggtgaa tatcataatc taaatcagtt ttaggactgc tctccaaaaa tcctgagtct
     7321 gagccgtagg acggaatcca aacagaggta aacttgcctg tatcaatact gtgttcttcc
     7381 atgaagtaga caccaacgta gatgccgatg tttttagcac ctagtgatgc tagttttgct
     7441 cgaaagtttt cgacaccttc gttcatatta gacatggttt tgtcttccac gtcaagccaa
     7501 tagtaactag ggctgtaagg agaggcagca ttgtagaaaa cttcggcagc cttttccatt
     7561 tcttggacac tttttccagc tacataagcg tagacagcaa ctgggacatt ccgcttttga
     7621 agttcagtga tatgactctt ataggccttg tctattccat tgataaatga agcatcattt
     7681 tcttttgttg tttgagcacc actgtgaaca cgaacaatag cacctgaaat attttgtgag
     7741 agggcatcgt agttgatttc ctcaggacgc tgccagccag agaggtcaat aatcggtttg
     7801 tctaagtgtt tcaaagcctg tgcttcaatc tgtgctatat tggattttgt tttaaacgat
     7861 tggctgtcat taagtgggcg attgatgatt aaaatgaaca tcataatccc aaaaaaacta
     7921 aataaaataa gtggatgaat ttgttttctc atatcttata agtctaccct aaaaatcaaa
     7981 aaaaatcaaa aaaatgggtt aaggaagaga ctttagagca ttttttcatt caagagtgcg
     8041 gaatgatttg aaatatggta taataaaagg gaatttctac agaaaagaga agattatgtc
     8101 aaattttgcc attattttag cagcgggtaa agggactcgc atgaaatctg atttgccaaa
     8161 agttttgcac aaggttgcgg gtatttctat gttggaacat gttttccgta gtgtgggagc
     8221 tatccaacct gaaaagacag taacagttgt aggacacaag gcagaattgg ttgaggaggt
     8281 cttggctgga cagacagaat ttgtgactca atctgaacag ttgggaactg gtcatgcagt
     8341 tatgatgaca gaacctatct tagaaggttt gtcaggacac accttggtca ttgcaggaga
     8401 tactccttta atcactggtg aaagcttgaa aaacttgatt gatttccata tcaatcataa
     8461 aaatgtggcc actatcttga ctgctgaaac ggataatcct tttggctatg gacgaattgt
     8521 tcgtaatgac aatgctgagg ttcttcgtat tgttgagcag aaggatgcta cagattttga
     8581 aaagcaaatc aaggaaatca acactggaac atacgtcttt gacaacgagc gtttgtttga
     8641 ggctttgaaa aatatcaata ccaataacgc tcaaggcgaa tactatatta cagacgtcat
     8701 tggtattttc cgtgaaactg gtgaaaaagt tggcgcttat actttgaaag attttgatga
     8761 aagtcttggg gtaaatgacc gtgtggcgct tgcgacagct gagtcagtta tgcgtcgtcg
     8821 catcaatcat aaacacatgg tcaacggtgt tagctttgtc aatccagaag caacttatat
     8881 cgatattgat gttgagattg ctccggaagt tcaaatcgaa gccaatgtta ccttgaaagg
     8941 gcaaacgaaa attggtgctg agactgtttt gacaaacggt acttatgtag tggacagcac
     9001 tatcggagca ggagcggtca ttaccaattc tatgattgag gaaagtagtg ttgcagacgg
     9061 tgtgacagtc ggtccttatg ctcacattcg tccaaattca agtctgggtg cccaagttca
     9121 tattggtaac tttgttgagg tgaaaggatc ttcaatcggt gagaatacca aggctggtca
     9181 tttgacttat atcggaaact gtgaagtggg aagcaacgtt aatttcggtg ctggaactat
     9241 tacagtcaac tatgacggca aaaacaaata caagacagtc attggagaca atgtctttgt
     9301 tggttcaaat tcaaccatta ttgcaccagt agaacttggt gacaattccc tcgttggtgc
     9361 tggttcaact attactaaag acgtgccagc agatgctatt gctattggtc gcggtcgtca
     9421 gatcaataaa gacgaatatg caacacgtct tcctcatcat cctaagaacc agtaggagcc
     9481 tatcatggag tttgaagaaa aaacgcttag ccgaaaagaa atctatcaag gaccaatatt
     9541 taaactggtc caagatcagg ttgaattacc agaaggcaag ggaactgccc gacgggattt
     9601 gattttccac aatggggctg tctgtgtttt agcagtaacg gatgaacaaa aacttatctt
     9661 ggtcaagcag taccgcaaag ctatcgaggc tgtctcttac gaaattccag ccggaaaatt
     9721 ggaagtagga gaaaacacag cccctgtggc agctgccctt cgtgaattag aggaagaaac
     9781 agcctataca gggaaattag aactcttgta cgatttttat tcagctattg gcttttgtaa
     9841 tgagaagtta aaactatatt tagcaagcga tttgacaaaa gtggaaaatc cgcgtccgca
     9901 ggatgaggat gaaaccttgg aagtccttga agtgagctta gaagaagcga aagaattaat
     9961 ccaatcaggt catatctgtg atgccaagac aattatggct gttcagtatt gggagttgca
    10021 gaaaaaatag aggaggtcag tatgggtaaa tctttattaa cggatgaaat gattgaaaga
    10081 gctaatagag gcgaaaaaat ttcaggtcct cctttgctag atgataatga ggaaactaag
    10141 attttaccaa cctcttcttc ccgttttggt tatgccaatc ctaaggatca tggttttagc
    10201 caggaaacct tgaagattca ggtcgaacca tctattcata aaagccgtcg tattgaaaat
    10261 accaagagaa atgtcttcaa ttctaagttg aataaaatct tatttgcggt catctttctc
    10321 ttgattttgc ttgttttagc aatgaaactt ttgtaataga aaaggaattg aaatgaaaat
    10381 aggaattatt gctgctatgc cagaagaact ggcttatctg gtccagcatt tagataatac
    10441 ccaggagcaa gttgttttgg ggaataccta tcatacagga accattgctt ctcatgaagt
    10501 cgttcttgta gaaagtggaa ttggtaaggt catgtctgct atgagtgtgg cgattttggc
    10561 tgatcatttc caggtggatg cccttattaa tacgggttca gctggggcag tagcagaagg
    10621 tatcgctgtt ggggatgtcg tgattgctga caaattagcc tatcatgacg tggatgtcac
    10681 agcttttggc tatgcttatg gacaaatggc gcaacaaccg ctttatttcg aatcagacaa
    10741 aacctttgtt gctcaaatcc aagagagttt atctcaattg gaccaaaact ggcatcttgg
    10801 tttgattgct acaggagata gttttgttgc aggaaatgac aagatagaag cgattaagtc
    10861 ccatttccca gaagttttag ccgtggagat ggagggggca gctattgctc aagcagcgca
    10921 tgccctcaat ctcccagtct tagtcatcag agctatgagt gacaatgcca accatgaagc
    10981 aaacatcttt tttgatgagt ttattatcga agctggacgt cgctctgccc aagtcttgtt
    11041 gacctttttg aaggctttag attaagcgga aatttgacag tttttctagc ttatgataag
    11101 atttaagtaa agaaaagcta gaaaacgttt cagaggatat tatgagtatt gaaatgaccg
    11161 tcagtgagat tgcagaggtc ttaggattat ctcgccaagc aatcaataac cgtgtcaaag
    11221 aattaccaga agaagacaca gataaaaatg acaaaggggt aacagttgtt accagaagtg
    11281 gcttgattaa gctagaagaa atctataaaa aaacgatttt tgaagatgag cctgtcagtg
    11341 aagatgtcaa acaacgtgaa ctgatggaga ttctagtgga tgagaagaat gcagaaattc
    11401 ttcgtcttta tgaacaatta aaagccaagg atcgtcagtt atcagaaaaa gacgagcaga
    11461 tgcgtatcaa agaccgtcag attgctgaga aagacaaaca attagatcag caacaacaat
    11521 tgacccttca agccatgaag gatcaagaaa atcttaagct agagctggac caagcaaaag
    11581 aagaagtcca atccactaag aaaggctttt ttgctcgttt atttggagga taatcaagga
    11641 gctgtttagg ttaaatgcta acctgatggc ttcttttgtt tgtgaatagt atagttgatt
    11701 agaacagaga cagtagagga gaggtacaga atggaacgat tagaagatta cattgctttt
    11761 gacttagaat ttaatcagca cgaaggacaa acacacttga ttcaagtatc ggcagtgcgt
    11821 tttagagatg gtcgggaaat cgatgcctat gattcctatg ttcataccag cgtccctcta
    11881 aaaagcttta tcaatggttt gaccgggatt acagctgaga ccttaaaaga tgctcctcca
    11941 gttgagaaag tcttagaaga attccaagag tttgtgggtt ctttgctgat gataggctac
    12001 aatgctgcta aaagtgattt acctatttta gcagagcatg gtttagacta tagccaacag
    12061 tacaaggtgg atttgtatga tgaagctttt gaacgtcgga gttcagattt acatggtatt
    12121 gccaatctca aattgcaaac tgttgcctca tttcttggat ttcaaggtca gtctcataat
    12181 agtttagagg atgctcggat gacggcgcgt gtttacgaat ccttcttaga gtcggatcaa
    12241 gctagggaat tgttagagac agaaagtagc ttatcaaaca atccttttgg tgtcttggac
    12301 ttgtctcaat tatttgacta ggagtgccta tgaaacctga aaaacctaaa aaattgggtc
    12361 ttaaacagat ttacctcaat cttgataaaa tcctctttct atttttcttg atttttatga
    12421 tagtggagta tttgtgggta ccattcaatt catggttggc tagcttctta ttagatcaga
    12481 caggttatct ttttatttcc tataacaatg tcttagccat ccttactcat tctccattga
    12541 ttagtctagc ttttttagcc ttgattgtaa ttaaccttct ggttgcttat tttcaaatag
    12601 gactcctctt tattggtgct cgtcatctcc tctataatga aaagcgaagg ctaattgagt
    12661 atatccgcaa ggttttccat gaaagttttg gatttatgaa aaagctaact tgcgctaaag
    12721 ccttgtttat ctttttctat atagctatgc tttttccttt tatacggaaa atgctgaaga
    12781 tttattatct taataaaatc gtcattccag agtttatcca agcttattta gaagataaat
    12841 attggatgtg gtggctgagc atcctacttc tatctcttat ctttctctat gtctctgtca
    12901 gattgatgtt tgcccttccg aagattgtat atgatcagct gactgttcga gaagcagtga
    12961 tgtttagctt ggagaaaacc aagaagagag ttacttttta tgcttggaat ttattttaca
    13021 tcttgctcaa agcacattta ttattttatc ttcctttgat tcctttatta ttggctcaaa
    13081 ctttggtaga tgatatcact cagagagagt ctctgattct tggtattttg aattttgtcg
    13141 tgattaaaaa tctctattat atggctctga cttatttttt ggttaaattt gtttcatttt
    13201 tgacaggaaa ggagctggat atgcttccta ggagagaaaa agatcacatc gtgcgatggg
    13261 gtgtcatgac ttgtgccagt cttttctttg ccttagaagg ttatatttat ctggaggctc
    13321 ccatggttca tctacctcaa cttatttctc accgaggggt ttccaatgca aatgggattc
    13381 aaaatacagt agagtccttg gaaactacag cacaactcaa accagacttg gtggagacgg
    13441 acgtgcagga aacaaaagat gggcagtttg tcatgatgca tgatgctaac ttgaaaaatc
    13501 tagcaggtat caataaaagt cctcaagact taaacttgga ggagcttaaa gggattgata
    13561 tttttgaaaa tggctaccag actaaaattt caagctttga agattatctc agtcgagcca
    13621 acgaacttgg tcaaaaatta ctaattgaaa ttaaaaccag taaaaaagat agtccagaca
    13681 tgatgaaccg ctttttagcc cgttatgctg caaagctcaa gatttatgga catcaaatcc
    13741 agtctttaga ctaccatgtt gtcgaaaaag taagacagta tgatgccgaa ctgccagttt
    13801 atttcatcat gccctacaat tctgtctttc ctaaaacaag agcgacagga tatactatgg
    13861 agtactcaac cttggatgaa tattttgtaa gcaaactatg gacaacggat cagaaacttt
    13921 atgtctggac tgtcaatgat tcagaagcta tcagcaaatc tcttcactta ggagtagatg
    13981 gagtgattac agatgatttg gaaaaagttc agcgggaaat agaagtagcc caagaagatc
    14041 cagaatatac ggatttgctc ttgaaaaaag cattggaatt ctttgaattt tagtaataaa
    14101 aaagaggaac ggttgttcct cccatgatag gtaagtattc ttgtgaatgc ttgctttttt
    14161 gtggttgcaa tccgtttacg agaattgttt gtattgttct tgtttcaatt tactttatag
    14221 tgctttgaag ttggaatgct acactataac ttct
//
LOCUS       DAVBBO010000055        14236 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ST1
            SAMEA2066453-rid20184263.denovo.055, whole genome shotgun sequence.
ACCESSION   DAVBBO010000055 DAVBBO010000000
VERSION     DAVBBO010000055.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2066453
            Sequence Read Archive: ERR351777
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 14236)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14236)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980402.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980402.1
            Genome Coverage       :: 176x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:17:33
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,141
            CDSs (total)                      :: 2,104
            Genes (coding)                    :: 1,953
            CDSs (with protein)               :: 1,953
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 16S)
            partial rRNAs                     :: 1 (23S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 151
            CDSs (without protein)            :: 151
            Pseudo Genes (ambiguous residues) :: 0 of 151
            Pseudo Genes (frameshifted)       :: 73 of 151
            Pseudo Genes (incomplete)         :: 76 of 151
            Pseudo Genes (internal stop)      :: 40 of 151
            Pseudo Genes (multiple problems)  :: 32 of 151
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14236
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2066453-rid20184263.denovo.055"
                     /strain="ST1"
                     /db_xref="taxon:1313"
     gene            complement(159..1085)
                     /locus_tag="VQU30_001735"
     CDS             complement(159..1085)
                     /locus_tag="VQU30_001735"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398914.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HET2447800.1"
                     /translation="MISRFFRHLFEALKSLKRNGWMTVAAVSSVMITLTLVAIFASVI
                     FNTAKLATDIENNVRVVVYIRKDVEDNSQTIEKEGQTVTNNDYHKVYDSLKNMSTVKS
                     VTFSSKEEQYEKLTEIMGDNWKIFEGDANPLYDAYIVEANTPNDVKTIAEDAKKIEGV
                     SEVQDGGANTERLFKLASFIRVWGLGIAALLIFIAVFLISNTIRITIISRSREIQIMR
                     LVGAKNSYIRGPFLLEGAFIGLLGAIAPSVLVFIVYQIVYQSVNKSLVGQNLSMISPD
                     LFSPLMIALLFVIGVFIGSLGSGISMRRFLKI"
     gene            complement(1078..1770)
                     /gene="ftsE"
                     /locus_tag="VQU30_001736"
     CDS             complement(1078..1770)
                     /gene="ftsE"
                     /locus_tag="VQU30_001736"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012130521.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division ATP-binding protein FtsE"
                     /protein_id="HET2447801.1"
                     /translation="MSIIEMRDVVKKYDNGTTALRGVSVSVQPGEFAYIVGPSGAGKS
                     TFIRSLYREVKIDKGSLSVAGFNLVKIKKKDVPLLRRSVGVVFQDYKLLPKKTVYENI
                     AYAMEVIGENRRNIKRRVMEVLDLVGLKHKVRSFPNELSGGEQQRIAIARAIVNNPKV
                     LIADEPTGNLDPDNSWEIMNLLERINLQGTTILMATHNSQIVNTLRHRVIAIENGRVV
                     RDESKGEYGYDD"
     gene            complement(1788..2883)
                     /gene="prfB"
                     /locus_tag="VQU30_001737"
     CDS             complement(join(1788..2810,2812..2883))
                     /gene="prfB"
                     /locus_tag="VQU30_001737"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015511312.1"
                     /ribosomal_slippage
                     /note="programmed frameshift; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 2"
                     /protein_id="HET2447802.1"
                     /translation="MDISVIRQKIDANREKLASFRGSLDLEGLEEEIAILENKMTEPD
                     FWNDNIAAQKTSQELNELKNTYNTFHKMEELQDEVEILLDFLAEDESVHDELVAQLAE
                     LDKIMTSYEMTLLLSEPYDHNNAILEIHPGSGGTEAQDWGDMLLRMYTRYGNAKGFKV
                     EVLDYQAGDEAGIKSVTLSFEGPNAYGLLKSEMGVHRLVRISPFDSAKRRHTSFTSVE
                     VMPELDDTIEVEIREDDIKMDTFRSGGAGGQNVNKVSTGVRLTHIPTGIVVQSTVDRT
                     QYGNRDRAMKMLQAKLYQMEQDKKAAEVDSLKGEKKEITWGSQIRSYVFTPYTMVKDH
                     RTSFEVAQVDKVMDGDLDGFIDAYLKWRIS"
     gene            complement(2991..3647)
                     /locus_tag="VQU30_001738"
     CDS             complement(2991..3647)
                     /locus_tag="VQU30_001738"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004256822.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CBS domain-containing protein"
                     /protein_id="HET2447803.1"
                     /translation="MAVKDFMTRKVVYISPDTTVSHAADLMREQGLHRLPVIENDQLV
                     GLVTEGTIAQASPSKATSLSIYEMNYLLNKTKVKDVMIRDVVTVSGYASLEDATYLML
                     KNKIGILPVVDNHQVYGVITDRDVFQAFLEIAGYGEEGIRVRFVTEDEVGVLGKIVSL
                     IVEENLNISHTVNIPRKDGKVIIEVQIDESIDLPALREKFEANGIQVEEIARTSAKVL
                     "
     gene            complement(4112..4822)
                     /locus_tag="VQU30_001739"
     CDS             complement(4112..4822)
                     /locus_tag="VQU30_001739"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000062217.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET2447804.1"
                     /translation="MSMLKVENLSVHYGMIQAVRDVSFEVNEGEVVSLIGANGAGKTT
                     ILRTLSGLVRPSSGKIEFLGQEIQKIPAQKIVAGGLSQVPEGRHVFPGLTVMENLEMG
                     AFLKKNREENQANLKKVFSRFPRLEERKNQDAATLSGGEQQMLAMGRALMSTPKLLLL
                     DEPSMGLAPIFIQEIFDIIQDIQKQGTTVLLIEQNANKALAISDRGYVLETGKIVLSG
                     TGKELASSEEVRKAYLGG"
     gene            complement(4822..5586)
                     /locus_tag="VQU30_001740"
     CDS             complement(4822..5586)
                     /locus_tag="VQU30_001740"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002913097.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET2447805.1"
                     /translation="MALLEVKQLTKHFGGLTAVGDVTLELNEGELVGLIGPNGAGKTT
                     LFNLLTGVYEPSEGTVTLDGHLLNGKSPYKIASLGLGRTFQNIRLFKDLTVLDNVLIA
                     FGNHHKQHVFTSFLRLPAFYKSEKELKAKALELLKIFDLDGDAETLAKNLSYGQQRRL
                     EIVRALATEPKILFLDEPAAGMNPQETAELTELIRRIKDEFKITIMLIEHDMNLVMEV
                     TERIYVLEYGRLIAQGTPDEIKTNKRVIEAYLGGEA"
     gene            complement(5586..6542)
                     /locus_tag="VQU30_001741"
     CDS             complement(5586..6542)
                     /locus_tag="VQU30_001741"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398913.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid ABC transporter
                     permease"
                     /protein_id="HET2447806.1"
                     /translation="MKENLKVNILWLLLLLAGYSLISVLVSVGVLNLFYVQILQQIGI
                     NIILAVGLNLIVGFSGQFSLGHAGFMAIGAYAAAIIGSKLPTYGAFFGAMLVGALLSG
                     AVALLVGIPTLRLKGDYLAVATLGVSEIIRIFIINGGSLTNGAAGILGIPNFTTWQMV
                     YFFVVITTIATLNFLRSPIGRSTLSVREDEIAAESVGVNTTKIKIIAFVFGAITASIA
                     GSLQAGFIGSVVPKDYTFINSINVLIIVVFGGLGSITGAIVSAIVLGILNMLLQDVAS
                     VRMIIYALALVLVMIFRPGGLLGTWELSLSRFFKKSKKEEQN"
     gene            complement(6546..7415)
                     /locus_tag="VQU30_001742"
     CDS             complement(6546..7415)
                     /locus_tag="VQU30_001742"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid ABC transporter
                     permease"
                     /protein_id="HET2447807.1"
                     /translation="MLQQLVNGLILGSVYALLALGYTMVYGIIKLINFAHGDIYMMGA
                     FIGYFLINSFQMNFFVALIVAMLATAILGVVIEFLAYRPLRHSTRIAVLITAIGVSFL
                     LEYGMVYLVGANTRAFPQAIQTVRYDLGPISLTNVQLMILAISLILMILLQVIVQKTK
                     MGKAMRAVSVDSDAAQLMGINVNRTISFTFALGSALAGAAGVLIALYYNSLEPLMGVT
                     PGLKSFVAAVLGGIGIIPGAALGGFVIGLLETFATAFGMSDFRDAIVYGILLLILIVR
                     PAGILGKNVKEKV"
     gene            complement(7683..8843)
                     /locus_tag="VQU30_001743"
     CDS             complement(7683..8843)
                     /locus_tag="VQU30_001743"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002206202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HET2447808.1"
                     /translation="MKKKFALSFVALASVALLAACVEVKSGAVNTAGNSVEEKTIKIG
                     FNFEESGSLAAYGTAEQKGAQLAVDEINAAGGIDGKQIEVVDKDNKSETAEAASVTTN
                     LVTQSKVSAVVGPATSGATAAAVANATKAGVPLISPSATQDGLTKGQDYLFIGTFQDS
                     FQGKIISNYVSEKLNAKKVVLYTDNASDYAKGIAKSFRESYKGEIVADETFVAGDTDF
                     QAALTNMKGKDFDAIVVPGYYNEAGKIVNQARGMGIDKPIVGGDGFNGEEFVQQATAE
                     KASNIYFISGFSTTVEVSAKAKAFLDAYRAKYNEEPSTFAALAYDSVHLVANAAKGAK
                     NSGEIKDNLAKTKDFEGVTGQTSFDADHNTVKTAYMMTMNNGKVEAAEVVKP"
     gene            complement(8944..9192)
                     /locus_tag="VQU30_001744"
     CDS             complement(8944..9192)
                     /locus_tag="VQU30_001744"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000462128.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlbG family protein"
                     /protein_id="HET2447809.1"
                     /translation="MFEKVNRSGLIIYLYYNRDAKKLQDYGDITYHSKKHRYLQLYVP
                     TQEVEQLVGRLSKEKFIKKVRVCHIQELETPFVGNLYR"
     gene            complement(9271..9861)
                     /gene="clpP"
                     /locus_tag="VQU30_001745"
     CDS             complement(9271..9861)
                     /gene="clpP"
                     /locus_tag="VQU30_001745"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000613477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease proteolytic subunit
                     ClpP"
                     /protein_id="HET2447810.1"
                     /translation="MIPVVIEQTSRGERSYDIYSRLLKDRIIMLTGPVEDNMANSVIA
                     QLLFLDAQDSTKDIYLYVNTPGGSVSAGLAIVDTMNFIKADVQTIVMGMAASMGTVIA
                     SSGAKGKRFMLPNAEYMIHQPMGGTGGGTQQTDMAIAAEHLLKTRNTLEKILAENSGQ
                     SMEKVHADAERDNWMSAQETLEYGFIDEIMANNSLN"
     gene            complement(10035..10664)
                     /gene="upp"
                     /locus_tag="VQU30_001746"
     CDS             complement(10035..10664)
                     /gene="upp"
                     /locus_tag="VQU30_001746"
                     /EC_number="2.4.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002883819.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil phosphoribosyltransferase"
                     /protein_id="HET2447811.1"
                     /translation="MGKIEVINHPLIQHKLSILRRTDTSTKAFRELVDEIAMLMGYEV
                     LRDLPLEDVEIETPITKTVQKQLAGKKLAIVPILRAGIGMVDGLLSLVPAAKVGHIGM
                     YRDEETFQPVEYLVKLPEDIDQRQIFVVDPMLATGGSAILAVDSLKKRGASNIKFVCL
                     VSAPEGVKALQEAHPDVEIFTAALDERLNEHGYIVPGLGDAGDRLFGTK"
     gene            complement(10753..11220)
                     /locus_tag="VQU30_001747"
     CDS             complement(10753..11220)
                     /locus_tag="VQU30_001747"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000138511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytidine/deoxycytidylate deaminase family
                     protein"
                     /protein_id="HET2447812.1"
                     /translation="MTEKRLAWDEYFAAQALLIANRSTCKRAKVGAILVKDNKVISTG
                     YNGSVSGTEHCIDHECLVIEGHCVRTLHAEVNAILQGAERGVPKGFTAYVTHFPCLNC
                     TKQLLQVGCKRVVYINQYRMDDYAQYLYQEKGTELTHLPLETVQTALKEADLM"
     gene            complement(11239..11796)
                     /locus_tag="VQU30_001748"
     CDS             complement(11239..11796)
                     /locus_tag="VQU30_001748"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000003900.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HET2447813.1"
                     /translation="MSERRISEKSLENLRKSNQESNLLTREAIETALLQLLEKKELTK
                     ISISELVKRAGVSRAAFYRNYDSKEEILESVFKRTVHNIMEQLHHYDLKTDLYLVWVH
                     LFREARKEARVIQLALDYHLEKIFVQAMQEFLEKYHGKSKGVSSYLHSFWSSAIVSVL
                     LKWIKDGMKVPAEKIADLGLPFFKK"
     gene            11921..12766
                     /locus_tag="VQU30_001749"
     CDS             11921..12766
                     /locus_tag="VQU30_001749"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000219932.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HET2447814.1"
                     /translation="MTWKIIADSGCDYRQLPTPAINTTFVSVPLTIQVADQVFVDDAS
                     LDIDQMMETMYATAEASKSACPSPDDYLRAFEGAKNIFLVTITGTLSGSHNSAQLAKN
                     IYLEDHPDTKIHVIDSLSAGGEVDLLVEKLNDLIDQGLSFEEVVEAITAYQEKTKLLF
                     VLAKVDNLVKNGRLSKLIGTVVGLLNIRMVGKASETGTLELLQKARGSKKSVQAAYDE
                     LVKAGYAGGRIVMAQRNNEKCCQQLSERIRETFPQADIKILPTSGLCSFYAEDGGLLM
                     GYEID"
     gene            12825..13997
                     /locus_tag="VQU30_001750"
     CDS             12825..13997
                     /locus_tag="VQU30_001750"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000680052.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HET2447815.1"
                     /translation="MKHFDTIVIGGGPAGMMATISSSFYGQKTLLIEKNRKLGKKLAG
                     TGGGRCNVTNNGSLDNLLAGIPGNGRFLYSVFSQFDNHDIINFFTENGVKLKVEDHGR
                     VFPASDKSRTIIEALEKKITELGGQVATQIEIVSVKKVDDQFVLKSADQTFTCEKLIV
                     TTGGKSYPSTGSTGFGHEIARHFKHTITDLEAAESPLLTDFPHKALQGISLDDVTLSY
                     GKHVITHDLLFTHFGLSGPAALRMSSFVKGGEVLSLDVLPQLSEKDLVTFLEENREKS
                     LKNALKTLLPERLAEFFVQGYPEKVKQLTEKEREQLVQSIKELKIPVTGKMSLAKSFV
                     TKGGVSLKEINPKTLESKLVPGLHFAGEVMDINAHTGGFNITSALCTGWVAGSNPI"
     gene            14048..>14236
                     /locus_tag="VQU30_001751"
     CDS             14048..>14236
                     /locus_tag="VQU30_001751"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000400041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1697 domain-containing protein"
                     /protein_id="HET2447816.1"
                     /translation="MEHIILLRGVTPNGKNAIPKMSYLVDILTEADFQQVRTYIQSGN
                     IILESNLALEEIREQVHTL"
BASE COUNT         4231 a         3092 c         2607 g         4306 t
ORIGIN      
        1 aatttctagt gcgccaaatt tcaagttcaa attagccatc aagaagtctt ctctggggga
       61 cttctttgga agctcttttc ttctacgcat ctcttttcaa aaactcttgt agcaaaaaag
      121 gagattttac aatctcctca taaaagcagc tattttacct aaatcttcaa gaatcggcgc
      181 atggatattc ctgatcccaa tgaaccaatg aaaaccccaa tcacaaatag tagggcaatc
      241 atcaacggac taaataaatc tggactaatc atggatagat tttgccctac caacgatttg
      301 ttgacagatt ggtaaacaat ttgataaaca ataaagacca aaacagatgg tgcgatagct
      361 cccaataaac cgataaaggc tccttctaac aagaacggtc cacggatata actgttttta
      421 gctccaacca agcgcatgat ttgaatttcg cgactgcggg aaataatggt aatacgaatg
      481 gtatttgaaa tcaagaaaac tgcgataaaa attaacaaag cagcaatccc tagtccccaa
      541 acacggataa atgaagctaa cttgaagagt ctttctgtat tggcaccgcc atcttgaacc
      601 tcagagacac cttcaatttt tttagcatct tcggctatag tttttacatc atttggagtg
      661 tttgcctcta caatataggc atcatagaga ggattggcat ctccttcaaa gattttccag
      721 ttatctccca ttatctcggt taatttttca tattgttctt ctttacttga aaaggtaaca
      781 cttttaaccg tagacatgtt cttcaaagaa tcatatacct tgtggtagtc attatttgta
      841 acagtttgac cttctttttc aattgtctga ctattatctt ccacatcctt tcggatataa
      901 actactacac ggacattatt ttcaatatct gtagctagtt tcgctgtatt gaaaataaca
      961 gatgcaaata ttgccaccaa ggtcaaagta atcatgactg aactgacagc agctactgtc
     1021 atccaaccat ttcgtttcaa actttttaag gcttcaaata aatggcgaaa aaatctacta
     1081 atcatcgtat ccatactctc cttttgattc gtcacgaacg acacggccat tttcaatggc
     1141 aatgacacgg tggcgcaagg tatttacaat ctggctatta tgagtcgcca tcaaaatagt
     1201 tgtcccttgt aggttaatcc gttccaagag attcataatt tcccatgaat tatccggatc
     1261 cagatttcct gttggctcat cagctatcaa tactttggga ttatttacaa ttgcacgcgc
     1321 aatcgcaatt cgctgctgct ccccacctga gagttcattt gggaaagaac gaaccttatg
     1381 cttcaatcca accaagtcca aaacttccat cactcgtctt ttgatattac ggcgattttc
     1441 cccgattact tccatagcgt aagcaatatt ttcatagaca gttttctttg gtaacaattt
     1501 ataatcttgg aagacaaccc caacactacg acgtagaagc gggacatctt tctttttgat
     1561 cttaaccaga ttaaaaccag caactgatag acttccttta tcgattttta cttcacgata
     1621 cagagaacga ataaaagttg acttccctgc tcctgaaggt cctacgatgt aagcaaattc
     1681 ccccggttga acgctgaccg aaacaccgcg tagagcagtc gttccgttgt cgtatttttt
     1741 aacgacatct ctcatttcaa taattgacat gtgagttcct ttctatctta gctaattcgc
     1801 cacttgagat aagcatctat aaaaccatct aggtccccat ccataacctt atctacctga
     1861 gcaacctcaa agctagttcg gtgatctttt accatagtat aaggcgtgaa gacataagaa
     1921 cggatttggc ttccccaagt gatctccttt ttctcacctt tgagagaatc tacctccgca
     1981 gccttcttat cttgctccat ttgatagagc ttagcctgca acatcttcat ggcacgatct
     2041 ctatttccat actgggtacg atccactgtt gattggacaa caattccagt tggaatgtgg
     2101 gttaaacgta cacctgttga aaccttattg acgttttgtc caccggcacc acctgaacgg
     2161 aaggtatcca tcttgatatc atcttcacgg atttccactt caatagtatc atccaattct
     2221 ggcatcactt ctacagatgt gaaagaggta tggcgacgtt tggcagagtc aaatggtgag
     2281 attcgcacta agcggtgaac acccatttct gacttgagga gaccataggc attaggccct
     2341 tcaaatgata aagttaccga cttaatacca gcctcatcac ctgcttggta atccaacact
     2401 tccactttaa agcctttagc attaccataa cgagtataca tacgaagcaa catatcaccc
     2461 cagtcctgcg cctcagtacc accagaacct ggatggattt ccaagatggc attgttgtgg
     2521 tcataaggtt ctgacaagag tagagtcatc tcgtagctgg tcattatctt atcaagttcg
     2581 gctaactgcg ctaccagttc atcatgcact gactcgtctt cagccaaaaa atccaataaa
     2641 atttcgactt catcctgcaa ctcttccatc ttatggaagg tattgtaagt gttttttaat
     2701 tcattcaatt cttgcgacgt tttttgggcc gcaatattat cgttccaaaa atcaggttct
     2761 gtcatcttgt tttccaagat ggcaatctct tcctctagcc cttcgaggtc aaagagaccc
     2821 cctgaaagaa gctaattttt cacgatttgc gtcaattttc tgacgaatta ctgaaatgtc
     2881 cataaatact ccttttttac attatttcat tatagcatat tttatcattt ctttccatct
     2941 tttgctctaa tccccttttc atgaaaaaag aagcctttgg acttcccttc ttacaagact
     3001 tttgctgaag tgcgagcgat ttcttccact tgaataccat ttgcttcaaa tttttctctc
     3061 aaggctggta aatcaattga ttcatcgatt tgcacttcga taatcacctt accatcctta
     3121 cgcggaatat tgactgtatg ggagatattc aaattttctt ctacaatcaa agaaacaatt
     3181 tttccaagaa caccaacttc atcttctgta acaaagcgta cacgaatccc ttcttcgcca
     3241 taacctgcaa tttcaagaaa ggcttggaaa acgtcacggt cagtaataac tccgtatact
     3301 tgatggttat ctacgacagg gagaatacca atcttatttt tcaacatcag ataagttgca
     3361 tcttctagac tagcatagcc tgagacagtg acaacatcgc gaatcatgac atcttttact
     3421 tttgtcttat tcagaagata attcatctca tagatagaaa gacttgttgc tttagatgga
     3481 cttgcttgtg caatggttcc ctcagtcacc aaaccaacca attgatcatt ttcgataaca
     3541 ggcagacggt gcaaaccttg ctctctcatc aaatctgctg catgagatac tgttgtatct
     3601 ggactaatat aaactacctt gcgggtcata aaatctttaa ctgccatgag acttctcctt
     3661 ttctattctt atccctatta tacaatcttt ttgcaaatct atcaaacgct tacatttctt
     3721 tttcaaaatt tagaaaagta tgaataagct agcaaaaaga gctctaaaat cgagctctgt
     3781 gaatgaaggt aagaaacttt tcattcgatt ttttcaatta ttagaaatta agctttcaat
     3841 gtagatgcag atttgtttgc aatctcaatc taccggctaa aacaatcctc tggatttgat
     3901 gattgcttcg caatcttcat ccaccgacta aaaagggccc ccggactata ttgatgatta
     3961 cttcgtaatc tttatctgcc ggctaaaaca atcctctgga tttgatgatt gcttcgcaat
     4021 ctcaatctac cgactaaaaa gggcccccgg actatattga tgattacttc gtaatcttca
     4081 tctgccgact aaaacaatcc actggattgt tttagccacc tagatatgct tttctgactt
     4141 cttctgatga agcgagttct tttcctgttc ctgataggac gatttttcct gtttccaata
     4201 catatcctcg gtcagagatt gcaagtgctt tattggcatt ttgttcaatc aagaggacgg
     4261 ttgttccttg cttctgaata tcttgaatga tatcaaaaat ctcttggatg aagattgggg
     4321 caagtcccat tgatggttca tctaaaagaa gaagttttgg tgttgacata agagcgcgtc
     4381 ccatggcaag catttgttgt tcccctcctg aaagagtagc tgcatcttgg ttcttacgtt
     4441 cttcaagacg aggaaagcgt gagaaaacct tcttcaagtt agcttgattt tcttcacgat
     4501 ttttctttaa gaaagctccc atttcaagat tttccataac agtcaagcca ggaaagacgt
     4561 ggcgtccttc tggaacttgt gaaagaccac ctgccacgat tttctgagct ggtatttttt
     4621 ggatttcttg acctaaaaat tcaatctttc ctgaacttgg tcgaaccaaa cctgacaagg
     4681 tgcgaagaat agttgtctta cctgcaccgt tggcaccgat aagggaaaca acttctcctt
     4741 cattaacttc aaagcttaca tcacggactg cttggatcat accgtaatgc acagaaagat
     4801 tttcaacttt taacatagac attaggcttc acctcctaga taagcttcga taacgcgttt
     4861 attggtctta atttcgtctg gagttccttg agcaattaaa cggccatatt caagtacgta
     4921 gatacgttct gttacttcca tgaccagatt catatcgtgt tcaatcaaca tgattgtaat
     4981 cttaaattca tctttgatac gacgaattaa ctcagtcaat tcggctgttt cctgtgggtt
     5041 catacctgct gctggttcat ctaagaagag aattttaggt tccgtagcaa gggcacgaac
     5101 aatttccaaa cgacgttgtt gtccgtagga aagattttta gcaagagtct ctgcatcacc
     5161 atctaaatca aagattttca acaattccaa agctttagcc tttaattctt tttcactctt
     5221 gtaaaaagct ggtaagcgta agaaactagt aaaaacatgc tgtttgtgat ggtttccaaa
     5281 agcaatcaaa acattatcta aaactgttaa atctttaaag agacggatat tttggaaagt
     5341 acgtccaagt cccaaagagg caatcttata aggtgatttc ccattcaaaa ggtgaccatc
     5401 tagggttact gttccctcgc ttggttcata aacaccggtc aaaaggttga aaagggtggt
     5461 tttcccagct ccgtttggac cgattaatcc aaccagttcc ccttcgttca attcaagagt
     5521 cacatctcca acagctgtta gaccaccaaa atgtttggtt aactgtttta cttcaagtaa
     5581 tgccattagt tttgttcctc cttcttagat tttttaaaga aacgtgatag gctcagttcc
     5641 cacgttccaa ggagtccacc tggtctgaaa atcattacca ataccaaggc taaagcgtaa
     5701 ataatcatac gcacactagc aacatcttgg agaagcatat tcaaaattcc cagaacaata
     5761 gccgaaacaa tcgcacctgt aatggaaccg agtccaccaa atacaacaat aatcaaaacg
     5821 ttgattgagt taatgaaggt gtaatctttc ggtacaacag acccgataaa tcctgcctga
     5881 agtgacccag caatacttgc agtaatggca ccaaagacaa aagcgatgat tttaatttta
     5941 gtcgtattaa ccccaactga ctcagcagcg atttcatctt cacgaacaga gagggttgaa
     6001 cggccaattg ggctacgcaa gaagttcaag gttgcaatgg ttgtaatcac gacaaagaag
     6061 taaaccattt gccaagttgt aaagttagga atccctaaga tacctgccgc accatttgta
     6121 agacttccac cattgatgat aaagatacgg ataatttcag aaacacctag agttgctacc
     6181 gcaagatagt cccccttcaa gcgcaaggtt ggaatgccga caagtaaggc aactgctcct
     6241 gaaagcaaag cccctacaag catagctcca aagaaggcac cgtaggttgg taatttagaa
     6301 ccaataatag ctgctgcata ggcaccaatc gccatgaaac cagcatgacc aagtgaaaat
     6361 tgtcctgaaa aaccaacgat taagttgaga ccaacagcca aaataatatt aattccaatt
     6421 tgttgtaaaa tctgtacata gaatagatta agtactccga ctgaaaccag tacactaatc
     6481 aagctatagc cagctaacaa aaggagtaac catagaatat taacttttaa attttccttc
     6541 atcgtttaca ccttctcttt cacattctta ccaaggatac cagctgggcg gacaatcaag
     6601 atcaacaaca agattccata aacaatggca tcacggaaat ctgacatccc aaaggcagtc
     6661 gcaaaggttt ccaatagacc aatcacaaag ccaccaagag ccgcaccagg aataattccg
     6721 ataccaccaa gtactgcggc aacgaaagat ttaagacctg gagtaacccc catcaaaggc
     6781 tcaagagagt tataataaag agcaatcaga acaccagccg cacccgcaag agcagaaccc
     6841 aaagcgaagg taaagctaat cgtacggttt acattgatcc ccatcaattg cgccgcgtcg
     6901 ctatctactg atactgcacg catggctttc cccatcttag tcttttggac aatgacttgt
     6961 aacaaaatca tcaaaatcaa ggaaatggcc aaaatcatta actgcacatt tgttaagcta
     7021 attggtccca aatcatatcg aactgtttga atcgcttgag ggaaggcacg ggtattggca
     7081 ccaaccagat agaccattcc atactccaat aggaaagaaa ccccaatagc cgtaatcaaa
     7141 acagcaatac gagtagagtg gcgcaaaggt cggtaagcaa gaaactcaat cacgacacca
     7201 agaatagctg tcgctagcat agctacaata agcgctacaa agaaattcat ttggaaagaa
     7261 ttgatcaaga aataaccgat aaaggctccc atcatataaa tatcaccatg ggcgaagttg
     7321 atgagcttga taattccgta aaccatggta tatcctaggg ctaacagcgc gtaaacacta
     7381 cctagaatca aaccatttac gagttgttgg agcataagat tcactctttc tatttataat
     7441 tccgagggtt ttccctcact ttttgatagg ttcttatact caatgaaaat caaagagcaa
     7501 actaggaaac tagccgcagg ttgctcaaag cactgctttg aggttgtaga taagactgac
     7561 gaagtcagtc acatatataa tccaaggcga cgttgacgca gtttgaagag attttcgaag
     7621 agtattaaat atcgaaacag ggagtgagtc aaaggctcat tccctatttc aacatttttc
     7681 tattatggtt ttacaacttc tgctgcttca actttaccat tgttcatggt catcatgtaa
     7741 gcagttttga ctgtgttgtg gtctgcatcg aagcttgttt gaccagttac accttcaaaa
     7801 tcttttgttt tagcaaggtt atccttgatt tcacctgaat ttttagcacc ttttgctgcg
     7861 tttgctacaa ggtgaactga atcataagcc aaggctgcaa atgttgaagg ctcttcattg
     7921 tacttagcac ggtaagcgtc aaggaaggct ttagctttag ctgaaacttc tacagtagtt
     7981 gagaagcctg agataaagta gatgtttgat gctttttcag cagttgcttg ttgtacaaac
     8041 tcctcaccgt tgaatccatc accaccaacg attggtttgt caattcccat gccacgcgct
     8101 tggtttacaa tcttaccagc ctcattatag taaccaggaa caacgatagc atcaaagtct
     8161 ttccctttca tgtttgtaag ggctgcttgg aagtctgtgt cacctgctac gaaagtttca
     8221 tctgcaacga tttcaccctt gtatgactcg cggaaagatt tagcaatccc tttagcatag
     8281 tcactggcat tgtcagtgta aagaacaact ttcttagcat ttaatttttc agaaacatag
     8341 tttgagataa tttttccttg gaagctatct tggaaagttc caataaagag gtaatcttga
     8401 cctttagtca atccatcttg agtcgcactt ggtgagatca atggaacacc tgcttttgta
     8461 gcgttcgcta ccgcagctgc agtcgcacca gatgtcgcag gtcctacgac tgctgatact
     8521 ttagattggg ttacaaggtt agttgtaact gaagcagcct cagctgtttc agacttatta
     8581 tctttatcga ctacttcgat ttgttttcca tcgataccac ctgcggcatt gatttcatca
     8641 acagccaatt gggcaccttt ttgttcagct gttccgtatg cagctaaaga acctgattct
     8701 tcaaagttaa acccgatttt aattgtcttt tcctctactg agttaccagc agtgttgact
     8761 gctccagact tcacttctac acaggctgca agaagtgcta cacttgcaag cgccacaaac
     8821 gatagggcaa attttttctt catctttttg tctccttatt tcttaaatag tctgttaaga
     8881 atataccgaa ttatcagaaa attgtcaatg ttttccttga actttttcga tgataacgtt
     8941 ttcctatcga taaagattgc ccacaaaggg tgtttccaac tcttggatat gacaaaccct
     9001 aactttttta ataaattttt ccttgctcaa gcgtccgacc aattgctcca cttcttgagt
     9061 tggaacatag agttgtaagt aacgatgttt cttggaatga taggtaatat ctccataatc
     9121 ctgcagtttt ttggcatcac gattatagta aagatagata atcaagccag agcgattgac
     9181 tttttcaaac atgataaatc ctctttctaa gaaatctctc cctattatac caaaaaaagc
     9241 aaacccagtc gagtttgcct tctatcatca ttagttcaat gaattgttgg ccataatttc
     9301 atcaataaag ccatattcaa gtgtttcctg ggcgctcatc cagttatcac gttctgcatc
     9361 tgcatggact ttttccattg actgacctga attttcagcc aagatttttt ccaaggtatt
     9421 acgagttttg agcaagtgtt ctgcagcgat agccatatca gtttgttggg taccaccacc
     9481 tgtaccgccc attggttggt gaatcatgta ttcagcattt ggaagcatga aacgtttgcc
     9541 ttttgctcca cttgatgcga tgactgttcc catagatgca gccattccca taacaatggt
     9601 ttggacatct gccttgataa agttcatggt atctacgatt gccaaaccag ctgaaacaga
     9661 accacctggt gtattgacat aaaggtaaat atcttttgta ctatcttggg catccaagaa
     9721 aagcagttgg gcaataacag agttagccat attgtcttca accggacctg tcagcataat
     9781 gatgcggtct ttgagaagac gtgagtaaat atcgtaagaa cgttctccac ggcttgtttg
     9841 ttcaataact acaggaatca ttcatttctc cttttgagtt ttaattttgt tggtcaaatg
     9901 actgaagata agactattat aatatcttgg tcaaaaaagg tcaaattttt gctctgcttt
     9961 cattagacag aaacaaaaac ccaacctcct ttcgtgactg gaaatacttt tccaagtcat
    10021 tcttcttttc gatcttattt tgtaccgaac aagcggtctc cagcatctcc aagacctgga
    10081 acgatataac cgtgttcgtt caaacgttca tccaaggctg ctgtaaagat ttctacatct
    10141 ggatgagctt cttgaagggc ttttacaccc tctggagcag atacaaggca gacaaatttg
    10201 atatttgatg cgccacgttt tttaagagaa tcaacagcca agattgctga gccacctgtt
    10261 gccaacattg ggtctactac aaaaatttga cgttggtcaa tgtcctcagg caatttcacc
    10321 aagtattcaa ctggttgaaa tgtttcttca tcacggtaca taccgatgtg gccaacttta
    10381 gcagctggaa ccaagctcaa gagaccatca accatcccga tacctgcacg caagattggg
    10441 acgatggcca atttcttacc tgccaattgt ttttgaactg tttttgtaat tggtgtttcg
    10501 atttccacat cttctagtgg aagatcacga agtacttcat accccatcaa cattgcaatc
    10561 tcatctacta gctcacgaaa agcttttgta gaagtatctg tacgacgcaa gattgacaat
    10621 ttgtgttgaa tcagtgggtg attaataact tcaatttttc ccatttttgg aattccttct
    10681 ttcaatttat tcttcttatt ataccaaaaa acgggttaaa aatctttcta aaccatttat
    10741 ttttgataat ttttacatta gatcagcctc tttaagagct gtctgtactg tctcaagtgg
    10801 taaatgggtc aattctgtcc ctttttcttg ataaaggtat tgggcgtagt cgtccattcg
    10861 gtactggttg atataaacca cacgcttgca gccgacctga agcaattgtt ttgtacagtt
    10921 gagacaagga aaatgggtta cataggctgt aaagcctttg ggaacaccac gctcagcacc
    10981 ttgaaggata gcattgacct cagcgtgaag ggtgcgaaca cagtggcctt caatgaccaa
    11041 acattcgtga tcaatacaat gctcagtccc tgacaccgaa ccattgtaac cagtggaaat
    11101 aaccttatta tcttttacca gaatcgcgcc cactttagca cgtttacaag tggaacgatt
    11161 cgcaattagt agagcttggg ctgcaaaata ctcatcccag gccagtcttt tttcagtcat
    11221 ctcttttctc ctttttctct attttttaaa aaatggtaaa cctaaatctg caatcttttc
    11281 agctggtacc ttcatgccat ccttgatcca ttttagaagg acagagacga tggctgagct
    11341 ccagaaggaa tgaagataag agctgacacc ttttgatttc ccatggtatt tttctagaaa
    11401 ttcctgcatg gcttggacaa agattttttc cagatggtaa tccaaggcca attgaattac
    11461 tctagcttcc tttctggcct cccggaaaag gtgaacccaa accaaataaa ggtctgtctt
    11521 taaatcgtaa tgatgcagct gttccataat attgtggaca gttcgtttaa agacgctctc
    11581 taaaatttcc tctttggagt cataattgcg ataaaaggcc gcacgcgaaa cacctgcacg
    11641 tttgaccaat tcagaaatac taatcttggt cagttccttt ttttccaaga gttgcaagag
    11701 ggctgtttca atggcttctc tggttaataa attggattct tggtttgatt ttctgagatt
    11761 ttcaagagac ttttcagaga ttctacgttc agacataaca ttttctttct acttgtcaca
    11821 acagacggat gatgcttttg tttcaagggt tttcatgata taattgtaaa aaaagacaga
    11881 acctttgtca atgtataact gacaaagatg gagaatttct atgacttgga agattattgc
    11941 tgactctggt tgtgattatc gtcaactgcc aacaccagct attaacacaa cctttgtaag
    12001 tgtcccctta accattcaag tagctgatca ggtctttgtt gatgacgcca gtctcgatat
    12061 tgaccaaatg atggaaacca tgtatgcaac tgcagaagct tcaaaatcgg cttgtccaag
    12121 cccagatgac tatttgcgag catttgaagg tgccaaaaac attttcctag taaccatcac
    12181 aggtaccctt tctggcagtc acaatagtgc tcaactagca aagaatattt atctggaaga
    12241 ccatcctgac actaagattc atgtgattga tagtttatct gctggtggtg aagttgacct
    12301 actcgtagaa aaattgaatg acttgattga ccagggcttg tcttttgaag aagtggttga
    12361 agctatcacc gcctatcaag aaaaaactaa gttgctcttt gtcctagcca aagtcgataa
    12421 cttggtgaag aacggccgtt tgagcaagct tatcggtacg gtcgttggcc ttctcaacat
    12481 tcgtatggtc ggaaaagcta gtgaaactgg aactctcgaa ttgctacaaa aagcaagggg
    12541 atcaaagaaa tcagttcaag ctgcctatga tgagttagta aaagctggat atgctggtgg
    12601 ccgtattgtc atggcccaac gcaataacga aaaatgttgt caacagctct cagagcgaat
    12661 ccgtgaaacc ttcccacaag cggatattaa aattctacca acctctggtc tctgcagttt
    12721 ctatgcagaa gatggcggtt tgctgatggg ctatgaaatt gattaattgt attcttgaca
    12781 agaggtgacc atcatctctt gtttttttgt ggtacaatag agctatgaaa cattttgata
    12841 ctattgtcat cggtggggga cctgctggta tgatggctac gatttccagt agcttttatg
    12901 gacagaaaac cctcctcatc gaaaaaaatc ggaaacttgg aaaaaaatta gctgggactg
    12961 gtgggggacg ttgcaatgtg accaacaatg gtagcttaga caacctgcta gctggaattc
    13021 ctggaaacgg acgctttctt tacagtgttt tctcccagtt cgataatcat gacatcatca
    13081 acttttttac agaaaatggt gttaaactta aggtcgaaga ccacggacgc gtctttccag
    13141 ccagtgacaa gtctcggact attatcgaag ctttggaaaa gaaaatcacc gaactaggtg
    13201 gtcaagttgc tactcaaata gaaatcgttt ctgttaaaaa agtagatgac cagtttgtcc
    13261 ttaagtcagc ggatcaaacc ttcacttgtg agaaactcat tgtcacaaca ggtggtaagt
    13321 cttatccttc gactggttcg actggttttg gtcacgagat tgctcgccat tttaagcata
    13381 ccatcaccga tcttgaggct gctgaaagtc ctttattaac agattttcca cataaagcct
    13441 tacaagggat ttctttggac gatgtgaccc taagttatgg taagcatgtc atcactcatg
    13501 atttactctt tacccacttt ggtttgtcag gtcctgctgc cctacgcatg tctagctttg
    13561 tcaaaggtgg ggaggttctc tcactcgatg ttttgcctca actttctgag aaggacttgg
    13621 ttacatttct agaagaaaat cgggaaaaat ccttgaaaaa cgctttaaaa accttgttac
    13681 cagaacgctt ggccgaattt tttgtacaag gatatcctga aaaagtcaaa caactgactg
    13741 aaaaggaacg agaacaactt gtccagtcca ttaaagaact taaaattcct gtaactggaa
    13801 aaatgtccct tgcaaagtcc tttgttacca agggtggagt cagtctcaag gaaatcaatc
    13861 ctaaaaccct tgaaagtaag ctggtacctg gcctccactt tgcaggcgaa gttatggata
    13921 tcaatgccca cacaggtggc tttaacatca cttctgccct ctgtaccggc tgggtggcgg
    13981 gatcaaatcc aatctaaata tacattacta aatggaacaa tcccccaaaa aaaagaaagg
    14041 aactactttg gaacatatta tcttgctaag gggagtcact cctaatggaa aaaatgctat
    14101 ccctaaaatg tcttatctag tagatatctt gacagaagct gattttcaac aagttcgaac
    14161 ttatattcaa agtggaaata ttattcttga aagtaactta gctctcgaag aaatacgaga
    14221 acaggttcat actcta
//
LOCUS       DAVBBO010000056        14039 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ST1
            SAMEA2066453-rid20184263.denovo.056, whole genome shotgun sequence.
ACCESSION   DAVBBO010000056 DAVBBO010000000
VERSION     DAVBBO010000056.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2066453
            Sequence Read Archive: ERR351777
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 14039)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14039)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980402.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980402.1
            Genome Coverage       :: 176x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:17:33
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,141
            CDSs (total)                      :: 2,104
            Genes (coding)                    :: 1,953
            CDSs (with protein)               :: 1,953
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 16S)
            partial rRNAs                     :: 1 (23S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 151
            CDSs (without protein)            :: 151
            Pseudo Genes (ambiguous residues) :: 0 of 151
            Pseudo Genes (frameshifted)       :: 73 of 151
            Pseudo Genes (incomplete)         :: 76 of 151
            Pseudo Genes (internal stop)      :: 40 of 151
            Pseudo Genes (multiple problems)  :: 32 of 151
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14039
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2066453-rid20184263.denovo.056"
                     /strain="ST1"
                     /db_xref="taxon:1313"
     gene            98..1357
                     /locus_tag="VQU30_001752"
     CDS             98..1357
                     /locus_tag="VQU30_001752"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TRZ/ATZ family protein"
                     /protein_id="HET2447817.1"
                     /translation="MKVFQHVNIVTCDQDFHVYLDGILAVKDSQIVYVGQDKPAFLEQ
                     AEQIIDYQGAWIMPGLVNCHTHSAMTGLRGIRDDSNLHEWLNDYIWPAESEFTPDMTT
                     NAVKEALTEMLQSGTTTFNDMYNPNGVDIQQIYQVVKTSKMRCYFSPTLFSSETETTA
                     ETISRTRSIIDEILKYKNPNFKVMVAPHSPYSCSRDLLEASLEMAKELNIPLHVHVAE
                     TKEESGIILKRYGKRPLAFLEELGYLDHPSVFAHGVELNEREIERLASSQVAIAHNPI
                     SNLKLASGIAPIIQIQKAGVAVGIATDSVASNNNLDMFEEGRTAALLQKMKSGDASQF
                     PIETALKVLTIEGAKVLGMENQIGSLEVGKQADFLVIQPQGKIHLQPQENMLSHLVYA
                     VKSSDVDDVYIAGEQVVKQGQVLTVEL"
     misc_feature    1433..1568
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00557"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="ribosomal protein L10 leader region; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /db_xref="RFAM:RF00557"
     gene            1607..2107
                     /locus_tag="VQU30_001753"
     CDS             1607..2107
                     /locus_tag="VQU30_001753"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001287276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L10"
                     /protein_id="HET2447818.1"
                     /translation="MSEAIIAKKAELVDVVAEKMKAAASIVVVDARGLTVEQDTVLRR
                     ELRGSEVEYKVIKNSILRRAAEKAGLEDLASVFVGPSAVAFSNEDVIAPAKILNDFSK
                     NAEALEIKGGAIEGAVASKEEILALATLPNREGLLSMLLSVLQAPVRNVALAVKAVAE
                     SKEDAA"
     gene            2183..2551
                     /gene="rplL"
                     /locus_tag="VQU30_001754"
     CDS             2183..2551
                     /gene="rplL"
                     /locus_tag="VQU30_001754"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018371186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L7/L12"
                     /protein_id="HET2447819.1"
                     /translation="MALNIENIIAEIKEASILELNDLVKAIEEEFGVTAAAPVAVAAA
                     DAADAGAAKDSFDVELTSAGDKKVGVIKVVREITGLGLKEAKELVDGAPALVKEGVAT
                     AEAEEIKTKLEEAGASVTLK"
     gene            2738..2908
                     /locus_tag="VQU30_001755"
     CDS             2738..2908
                     /locus_tag="VQU30_001755"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001168336.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2447820.1"
                     /translation="MQKEGQSSRQFVKSHLMTIMGVDIVKATQLVDEMEQVGLIRFDE
                     FGNVGILVLEGQ"
     gene            2908..3156
                     /locus_tag="VQU30_001756"
                     /pseudo
     CDS             2908..3156
                     /locus_tag="VQU30_001756"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017648301.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiator protein A"
     gene            3170..3510
                     /locus_tag="VQU30_001757"
                     /pseudo
     CDS             3170..3510
                     /locus_tag="VQU30_001757"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812122.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            3503..3883
                     /locus_tag="VQU30_001758"
     CDS             3503..3883
                     /locus_tag="VQU30_001758"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000565031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arsenate reductase family protein"
                     /protein_id="HET2447821.1"
                     /translation="MIDLYLSKNRQRNQLLLDFFQNYGIEVSCHSVSEMTKDKLIEMM
                     SYSSDCFEFLSPNLLRFKNRDNLRLTDFVEIILKNPELTIRLPLAVSNKRVYPSLNLE
                     EARALLPRDTKQLIYMAQTHYLSN"
     gene            3896..4039
                     /locus_tag="VQU30_001759"
     CDS             3896..4039
                     /locus_tag="VQU30_001759"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000840765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2447822.1"
                     /translation="MAERFWENLSIILAERNISWIELTRKMFAGEFHYPSELNRLYQK
                     IRH"
     gene            4132..4719
                     /locus_tag="VQU30_001760"
     CDS             4132..4719
                     /locus_tag="VQU30_001760"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000821297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HET2447823.1"
                     /translation="MKRIIPVYIFQQVNVLLVSLYLLKFLCIGELTILQILYGSSLIS
                     FLWMYGQRKQAHKVNMKSRMKWLGVEFVSLLIISLCFSLIHAQGSTNQANLIGLQHQI
                     PWFSFLLFLINASMVEEFLYREILWNLVRKLDIRVALTSVLFALAHHTGTILAWCLYV
                     SLGMFLGMVRYKSDLWGSMGLHLVWNLLVYSLLLF"
     gene            4921..5058
                     /locus_tag="VQU30_001761"
     CDS             4921..5058
                     /locus_tag="VQU30_001761"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004264816.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SapB/AmfS family lantipeptide"
                     /protein_id="HET2447824.1"
                     /translation="MAEEVLNLQLVSVQVDETDEVDGMRFSTFSTNRCGNWSAFSWEN
                     C"
     gene            5237..7846
                     /locus_tag="VQU30_001762"
     CDS             5237..7846
                     /locus_tag="VQU30_001762"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000386153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lanthionine synthetase"
                     /protein_id="HET2447825.1"
                     /translation="MDYNFNLEHPFFFTNNDYSTDTSIKYQVSLPFNWHEVMNNDEWV
                     YQYPIGKFVERQGWKIHISSEYNSSHELLQDVAKICHEMRIPFKHLSTEDKFIMRNGK
                     LVSRGFSGKFITCYPNQNELESVLQRLESALKQYNGPYILSDKRWDEAPIYLRYGVFR
                     PSRDDEKKVAIDELIVGDEVVKDERLPVFKIPKGIVPPDFLNKWLDKKDKKQGDFPFI
                     IDNAIRFSNSGGIYNARLKEDGKKIILKEARPYTGLGFDGTYSSEKLASECKALKILN
                     EWSETPKIYWHGKIWEHTFLGIEHMKGVPLNRWVTNNFPLYEVVDKTKDYLLRVSKIV
                     EKLIDLTNKFHSENVYHQDLHLGNILVKDEDEISIIDWEQAVFSNDEKVVHKVAAPGF
                     RAWRETLPSEIDWYGIRQIAHYLYMPLVTTSDLTYNYVSQTRIEGKKLFESLGYTREH
                     IDYVESLLSYLDSKCPQIENISRKKVLKPMHEIRTIESEQDIQDFIIKLLRGFTLTYG
                     QWRKEFQSRFFPVHYYGLNFNQGIAFSDLAILWSYQQLAKKVKNFKFDDYYEIRTQVI
                     NEAVNNFKKSSLSGLFDGKIGTIWLIYEFGEIDRAVELFTTHFIEIFENSQNKNLYSG
                     QAGILLVGLYFLSKGEIDNKLGEEILIRLREYTLNYIENPETFCKVGASDVQSNDPYE
                     NFGGLLYGHAGVAWLFGEAYKLTGESIYKNGLELAVDKELVAYKVDSNNSLQYSQGHR
                     LLPYLATGSAGLLLLINRNKEILSSKYLKYLTSLERATDVVFCVLPGLFNGFCGLEVA
                     NNIYSDIDDNFSGQKKLIEQLYRYLCVIEEGFVIAGDNGLKITTDIASGFAGVAIGLV
                     SIMDNKLTILPQI"
     gene            7879..9819
                     /locus_tag="VQU30_001763"
     CDS             7879..9819
                     /locus_tag="VQU30_001763"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004263477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S9 family peptidase"
                     /protein_id="HET2447826.1"
                     /translation="MNQSNEIFLNTIQEKTHYKRSISSSFQELKKWNSLIFRRGRYWY
                     QFDNWSIPNTGVIKEWYVEDNDWIPKVSSSSLDNSNSLKIVFDVEKYTLPDDSILQDV
                     RISSDESYIVLVVSSLRSTNLIGIKKYTMEELFIIEDISVESSFYLGKFGVMYTRSKE
                     YGRPSKLFYKSFDSFTEEELFEENECSFRLKIVHIDSNNCFVKSVDFQKGRIFLYSFD
                     RTGFVRHSYTETVAPTPRDIALFSTEKAQYFLGLSSTEEKKDQLILRETSSGDRVSIT
                     IPYQDRARRVHCIGRYILLDCSNAANSVFYLATFKNNSLRELSVNKITFDEKTTLYEN
                     SFSDRVLLFLERRTFYEKILSFDLIENTLKTEFERPIIKSNNTKYFSKVIWTKKDSYD
                     VSIPISLFWKSEDTDELPRRKKCILSVYGAYGKNDNSDLDEIMLSIIDAGFIYAIVHV
                     RGGGYLGGEWYRSGKALNKWNSIRDFIEGVNYLRENDVIDSKRLGLITSSAGGIIAGA
                     VLNEEKNLLQSILLFSPFINPYDTLQNPNDPLSKTEIAEWGDIRDPEVKAYIKSYSPM
                     QNIEKARDSNTVIVNILGEKDPYINNNEVIEWSKKLNSIGVKSLLYLNKAAGHGGFTP
                     SDVLLMIDTLNYFFEEVGRNNL"
     gene            9816..11423
                     /locus_tag="VQU30_001764"
     CDS             9816..11423
                     /locus_tag="VQU30_001764"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET2447827.1"
                     /translation="MNYLKFIKKTKLILMGILIFLSSFNGVLLSGIIVYAGSLNQTSS
                     FSDVLRFGAISILGWSAIYISNYYLEVTEASITKDINVKIKQGYFREQYLSSEMVKDY
                     SSIISVLSNDLRLIEENYFRQIFEIISSILLFIVSLSFMLYLNFLVSIIFIVLSALPI
                     IVPVFMKKMLSNSANEYSNSNAEYTHIIKEIFNGFKTLKSYSVTKEIISLSDKKLDKL
                     EDSTFNLKRSEVLSKLVAVLISGFCFLVPLVVGCYFVIYHKSLSFSELIGIFLANDKV
                     LGPIQSIAYSLNKINTTKDLRKPFLKYLSGEKNFIDAEHDNNGLYTSSIDEIHMKDVV
                     YSITPENKLSIDFSFKSPFRVLLTGTSGSGKTTILNLINGSLKPQKGYVNLLSHGKKS
                     SDSIPTVDQTPYIFDTTIRENVTLFQNEYFSDDQIIEVLKKVNLYEELEKIDILNYQC
                     GENGSNLSGGQKQKIALARALIRNNKVYLFDEISANLDNDNSNSIHDILFNLGISFIE
                     VSHHYDLNDKRYTDIYKLENGTLFKIK"
     gene            11438..12178
                     /locus_tag="VQU30_001765"
     CDS             11438..12178
                     /locus_tag="VQU30_001765"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000356590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET2447828.1"
                     /translation="MDKDYILKVKGLYHQFLLGNNKTLQVLKNVSLSASRGEFISILG
                     ISGSGKSTLLKCISSLLEPTSGEVILNGINPYKIRNAKLSSIRRNEVSFIFQAYNLIP
                     SLPVIENIALPLRLSQKKLTIKNVENLLKRMKFNAGLNDFVGTLSGGEQQKVAIARAV
                     IADSDIIFADEPTGALDSVSREVIFELLRELVGAGKCVIMVTHDIELASKTDRALILK
                     DGKIFKELHRPSGEELYKILEVQSTTEE"
     gene            12181..13500
                     /locus_tag="VQU30_001766"
     CDS             12181..13500
                     /locus_tag="VQU30_001766"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000945307.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2447829.1"
                     /translation="MLRLVYYQFLHNKKQWLGVSPVIFVSSLVMGLAVNGVINVENNS
                     QVFVGLPDPKPIFMFPIVFGGVTLFFVLSNIINMLVEIFRDDYELLEVLGASLLQLSF
                     LVGGQIFIISSIISFIAYLCSIFVTSNYYYFLQYFFGENILPDIQFQTSAVGCIITVV
                     LISFLAFLSGCFYTFKKIRNRKSSKIRHVLSIVKRILLLAGFSVIWLLSLQQIFQDST
                     ILAKAQIIFNIVILDIVIIYQLSPFIQSCFIKLLSIIIFRNNFMFIASKWNLLYRKPY
                     IKSISAAITGAILLISSFQMISQNILSQFQDDSDLELKVAFIVYVGAPILIVLANIIS
                     IAFLSSHQERIEIQQFEILGTSNYQMVKIKVGEAIFLTFVTSLIAFLLNIKIMALIYY
                     SLEDVLIDDMNLLGLILPNFIVSIILFILIFITKSSYFIFKNAKIIS"
     gene            13634..13771
                     /locus_tag="VQU30_001767"
     CDS             13634..13771
                     /locus_tag="VQU30_001767"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004264816.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SapB/AmfS family lantipeptide"
                     /protein_id="HET2447830.1"
                     /translation="MAEEVLNLQLVSVQVDETDEVDGMRFSTFSTNRCGNWSAFSWEN
                     C"
BASE COUNT         4691 a         1960 c         2777 g         4611 t
ORIGIN      
        1 agatagaact gacgaagtca gtaaccacac ctacggcaaa gtgaatctga agtggtttga
       61 agagagtaca acttgtcttt tagaaaagga gcctataatg aaagtctttc agcatgtaaa
      121 tatcgtgact tgtgatcaag atttccatgt ttatcttgat ggaatcttag cagtcaagga
      181 ttctcaaatc gtctatgtcg gtcaagataa gccagcgttt ttagagcaag ctgagcagat
      241 tatagactat cagggagctt ggattatgcc tggtttggtc aattgtcaca cccattctgc
      301 aatgacaggt ctgagaggga tccgagatga cagcaatctc catgaatggc tcaatgacta
      361 tatctggcca gcagaatctg agtttactcc cgacatgact accaatgcgg tcaaagaagc
      421 cctgacagag atgctccagt caggaacaac aacctttaac gatatgtata atcccaatgg
      481 tgtggatatc cagcaaattt atcaggtggt gaaaacttcc aagatgcgtt gttatttttc
      541 tccgactctc ttttcttcag agacagaaac aactgctgag actataagca gaactcgatc
      601 catcatagac gaaatcttaa aatataaaaa tccaaatttc aaggttatgg tagcacctca
      661 ttctccgtat agctgcagta gagacttgct ggaagcgagt ttggaaatgg caaaagagct
      721 aaatattccg ctccatgtcc atgtggcgga gaccaaggag gagtcaggaa ttatcctcaa
      781 acgatacggc aaacgccccc ttgcttttct tgaagaactg ggttatttag atcatccgtc
      841 cgtatttgct cacggggtcg aattaaacga gagagaaatt gaacgcttgg catcttctca
      901 agtggctatc gcccacaatc ctatcagtaa cctcaaactg gcatcaggaa ttgctccaat
      961 tatccagatc caaaaagcgg gagtagcagt cggaattgcg actgactcgg ttgcttccaa
     1021 taacaatcta gatatgtttg aggaaggaag gactgcagct cttcttcaga agatgaaaag
     1081 tggggatgcc agccagtttc caatcgaaac agctctcaag gtactgacaa tcgaaggggc
     1141 taaggtcctt ggaatggaaa atcagatagg aagtctggaa gtcggcaagc aagcagattt
     1201 tctggtcatt caaccacaag ggaaaattca tctccaacct caggaaaata tgctgtctca
     1261 cctggtttat gcagttaaat ctagtgatgt agatgatgtt tatatcgccg gagaacaggt
     1321 tgttaagcaa ggtcaagtcc tgacagtaga actttaaaag aaaaatcacg aaaaatttta
     1381 aaaaaagttt gcaaaaatct tgcattcttt ttttgactat gctatactta tatacggttt
     1441 aaaaaaactg cctaagacag taggggagct cgactcataa atatcctacc gaggacaaga
     1501 cgtatcatgt aaaaagaagc gtattgtact ttcgtgtcta ggtttgggcg cgtttttctt
     1561 tttgaaaaat tccccaagca aaataattac ggaggtgaac acactaatga gtgaagcaat
     1621 tattgctaaa aaagcggaac tagttgacgt agtagctgaa aaaatgaaag ctgctgcatc
     1681 tatcgtcgtt gtagacgctc gtggtttgac agttgagcaa gatacagttc ttcgtcgcga
     1741 gcttcgtgga agcgaagttg agtataaagt tattaaaaac tcaatcttgc gtcgtgcagc
     1801 tgaaaaagct ggtcttgaag atcttgcatc tgtatttgtt ggaccatctg cagtagcatt
     1861 ttctaatgaa gatgttatcg caccagcgaa aatcttgaac gacttttcta aaaacgctga
     1921 agcacttgaa attaaaggtg gtgcaatcga aggcgctgtc gcatctaaag aagagattct
     1981 tgcacttgca actcttccaa accgcgaagg acttctttct atgctccttt ctgtacttca
     2041 agcgccagtg cgcaacgttg ctcttgcagt caaagcggtt gcagaaagca aagaagacgc
     2101 ggcttaatct taagctacac agcgtagcct agctacgaaa aaaactatta taaaatttaa
     2161 aacttatttg gaggaaataa caatggcatt gaacattgaa aacattattg ctgaaattaa
     2221 agaagcttca atccttgaat tgaacgacct tgtaaaagct atcgaagaag aatttggtgt
     2281 aactgcagct gctcctgtag ctgttgctgc agctgatgca gctgatgctg gtgctgctaa
     2341 agattcattc gacgttgaat tgacatctgc aggcgacaaa aaagttggcg ttatcaaagt
     2401 tgtacgtgaa atcactggtc ttggtcttaa agaagctaaa gaacttgttg acggtgcacc
     2461 agcacttgtt aaagaaggcg ttgcaactgc agaagctgaa gaaatcaaaa ctaaattgga
     2521 agaagctgga gcttcagtta ctcttaaata atagagtatc gcaatttgat tgcggaatcc
     2581 ctatttacca gtctttgaga gcgataagcg attgatagaa actgataaat tgatttggtt
     2641 tcctgccaaa aattctttgg caggattttt gttttaataa actttcgggg gtagacacta
     2701 gattgtctac cccttttttt gtgtttcgga ggtaattatg caaaaggaag gacagtcatc
     2761 acgtcaattc gtgaagagtc atctcatgac tatcatggga gttgatattg taaaagcaac
     2821 tcagttagtt gatgaaatgg aacaagtagg tttaatccga tttgatgaat ttggaaatgt
     2881 tggaatttta gtcttggagg gacaataatg aagtgtatta ccgctaatca atatcagaca
     2941 tcagagcgtt attataagct ccccaaactt ttatttgaga gtgaacggta taagaatatg
     3001 aaactggagg ttaaggtggt ttactcagtt ttaaaagatc ggttggagtt gtctttgagc
     3061 aaaggttgga ttgatgagga tggggctatt tatttgattt attccaattc aaatttgatg
     3121 gcacttttag gctgttcaaa gtcaaaatta ctctccatgt gagtttgaag tgacattttt
     3181 agatgattac cataaaaaac ataactaccc actattttac gaatcctatc ttcaaaacgt
     3241 tatggaattc cttgaaagtc aagacataaa gaatggggtt gatgcctttg tagatgatca
     3301 tcaaaatctc gtttttgttt tatatggaca aggctatcga gccgagggaa aagagggaat
     3361 acttacaacc caagtaactg taaaagctta tgatgaagac aagaaaccga ttaacttcgc
     3421 aaatttatta gattccttaa tttattagat tccttaatcg tgtcagaata tcaaatggaa
     3481 ccgaatcttt gggaggtctc ccatgattga tctctatcta agtaaaaata gacaaagaaa
     3541 tcaacttctt ttagatttct tccaaaacta tggcatagag gtatcttgtc attcagtttc
     3601 tgaaatgaca aaggacaaat taattgagat gatgagctat tcttcagatt gttttgagtt
     3661 tttatctccc aatttattac gatttaagaa ccgtgacaat ctaagattaa cggatttcgt
     3721 tgagataatt ttaaaaaatc ctgaactaac catcagactt cctcttgcgg tttcaaataa
     3781 gcgagtttat ccaagtctga atttggaaga ggctagagct ctattgccaa gagatacgaa
     3841 acaattgatt tacatggcgc aaacacatta tttatctaac taaaggagaa gcaatatggc
     3901 tgaacgattt tgggagaact tgtccattat tttggctgaa agaaatatca gctggattga
     3961 gttaaccaga aaaatgtttg cgggagagtt tcactatcca agtgaattga atcgtttgta
     4021 tcaaaagatt cgccactaga agatggaaca atgaatgcct caaagtccat gggtagaaag
     4081 gattgtgcag gtattagatt tagattatga agatttattt cggaggtaac tatgaaaaga
     4141 ataattccag tttatatatt ccaacaagta aatgtcctat tggtatctct atacttattg
     4201 aaatttcttt gtatcggtga gttaactata ctacagattc tctatggttc gtcactcatt
     4261 tcttttttat ggatgtatgg ccaacgcaaa caagcgcata aggtcaatat gaaatctagg
     4321 atgaaatggc ttggtgttga atttgttagc ctactgatta taagtctatg ttttagtctg
     4381 attcatgctc aaggaagcac gaatcaagca aacttaattg gccttcaaca tcaaattcct
     4441 tggttttcat ttttattgtt cttaatcaat gcgagtatgg ttgaagaatt tctgtatcga
     4501 gaaattttat ggaatttggt cagaaaatta gatatcagag ttgctttgac aagtgtttta
     4561 tttgccttag cacatcatac aggaaccatt ctagcttggt gtttgtatgt ttcacttggg
     4621 atgtttttag gtatggtgcg ctataaatct gacttatggg gcagtatggg actacatttg
     4681 gtgtggaacc tactagttta tagtttgctg cttttttaaa ataggtgacc tgatttttag
     4741 gtaacttcta aaactaactt ccagttttgg gagagagatg gaagttactt tgaaaagtta
     4801 cggaaacatt attttctatg tgacaacatt gtataattgc ttgcatttta ctggtggaga
     4861 gagtataatg agggtggata aagtacttaa tcccaaaaat ttaaatagga ggagctagct
     4921 atggcagaag aagtattaaa tcttcaatta gtatctgttc aagttgacga aacagatgaa
     4981 gttgatggaa tgcgatttag tacattcagt acaaatcgtt gcggtaactg gagtgctttt
     5041 agttgggaaa attgttaatt catttaaatt gtaaacttta gagattctct ggagttatgg
     5101 atgtcgttcc aatatgtgca cgttggaatg ttagtgctta tatggggaga atccaaagga
     5161 ttctcccttt ttatttaaat aagtctgtct agctatagat atattaagtt tgataaaatt
     5221 tcttggagat tttgttatgg attataattt caatttggag catcctttct ttttcactaa
     5281 taatgattat agtacagata ctagcataaa gtaccaagta agtctgcctt ttaattggca
     5341 cgaagtaatg aataatgatg agtgggttta tcaataccct attggaaaat ttgttgaaag
     5401 acaagggtgg aaaatacaca ttagttcaga gtataacagt tcacatgaat tgttacaaga
     5461 tgtagcaaaa atttgccatg aaatgcgaat tccatttaaa catcttagta cagaagacaa
     5521 atttatcatg cgaaacggga aattggttag tcgaggattt tctggtaaat ttattacatg
     5581 ttatccaaat caaaatgaat tagagtcggt tttgcaaagg ttagaaagtg ccttaaagca
     5641 atataatggg ccatatattt taagcgataa acgttgggat gaagcaccaa tatatctgag
     5701 gtatggtgtg tttaggccgt caagggatga tgaaaagaag gttgctattg atgaattaat
     5761 tgttggcgat gaagttgtta aagatgaacg tttaccagta tttaaaattc caaaaggtat
     5821 agtgccccct gactttttga ataaatggct tgacaagaaa gataaaaaac agggagactt
     5881 tccctttatt atagataatg caattagatt ttcaaacagt ggtgggatat ataatgctag
     5941 gctaaaagaa gatgggaaaa aaataatttt aaaagaggct agaccgtata caggtctagg
     6001 atttgatggt acttattctt cagagaaatt agcttcggag tgcaaagcac taaaaattct
     6061 aaatgaatgg agtgagacgc ctaaaatata ctggcacggt aagatctggg agcacacctt
     6121 cttaggaatt gaacatatga agggcgttcc actaaataga tgggttacca ataattttcc
     6181 tttatatgaa gttgttgata agaccaaaga ttatctattg agagtttcaa agatagtaga
     6241 aaaactcatc gatttaacga ataagtttca ttctgaaaat gtatatcatc aagatttaca
     6301 tttaggaaat atcttggtta aggatgaaga tgagattagt ataatagact gggaacaggc
     6361 tgtcttttca aatgatgaaa aagttgtaca taaagttgca gcccctggtt ttagagcatg
     6421 gcgagaaaca cttcccagtg agatagattg gtatggtatt agacaaatag ctcattattt
     6481 atacatgcca ctagtaacta catcggattt gacatacaac tatgtaagtc aaaccaggat
     6541 agaaggaaaa aaactatttg agtctttggg ttatacaaga gaacatatag attatgtaga
     6601 aagtttattg tcatatctag attctaaatg tccacagatt gagaatattt ccaggaaaaa
     6661 agttttaaaa cccatgcatg agattagaac tatcgagagt gagcaagata tacaagattt
     6721 tattataaaa ttattgagag ggtttacgct aacttatgga cagtggcgta aagaatttca
     6781 atcaagattc ttcccagttc attattatgg tctgaatttt aatcaaggaa ttgcgttttc
     6841 agatttagct atcctttgga gttatcaaca actagctaag aaagtaaaaa atttcaagtt
     6901 tgatgactat tatgagattc gaacacaggt tattaatgag gcagtaaata attttaagaa
     6961 atcgtccctt tctggtcttt ttgatggtaa aattggtaca atctggctca tttatgaatt
     7021 tggggagata gatcgggcag ttgaactttt tacaactcat tttatagaga tatttgagaa
     7081 ttcacaaaat aaaaatttat atagtgggca ggctggaatt ttactggttg gactgtattt
     7141 tcttagtaaa ggggaaattg ataataaact aggagaagaa atactaatta ggcttagaga
     7201 atatacttta aattatatag aaaatccaga aactttttgt aaagttggcg ctagtgatgt
     7261 tcagagtaat gatccttatg agaattttgg tggattacta tatggtcacg caggggtagc
     7321 ttggctcttc ggtgaagctt ataaattaac tggtgaaagt atctataaaa atggtctaga
     7381 attggctgta gataaagaat tagttgctta taaagtagat agtaataatt cattgcagta
     7441 cagccaaggt catagattac taccatatct agcaactgga agtgctggcc tgcttttact
     7501 tattaataga aataaagaaa tcttgtcaag caaatactta aaatatttaa cttctttaga
     7561 gagggcaact gatgtagttt tttgtgtatt accaggttta tttaacggat tttgtggtct
     7621 tgaagttgct aataatatat atagtgatat cgatgataac ttttcaggac aaaagaaatt
     7681 aattgaacaa ctttatagat atttgtgtgt aattgaagaa ggatttgtta ttgcgggaga
     7741 taatggttta aagataacaa cagatattgc ttcgggattt gcgggtgttg caattggatt
     7801 ggtatcaata atggataata aattgacgat tcttcctcaa atataatatt tagataccat
     7861 tattaagggg tcatacttgt gaatcagagt aatgaaatat ttttaaatac aatacaggaa
     7921 aaaacacact ataagaggtc tatctcttca tcatttcagg aattaaaaaa atggaattct
     7981 ttgatattta ggagagggcg atattggtac caatttgata attggagtat acccaatact
     8041 ggtgtaataa aggaatggta tgtcgaagat aatgactgga ttcctaaggt tagttcttcc
     8101 agtttagaca attcaaattc acttaaaatt gtctttgatg tggaaaaata tactttgcca
     8161 gatgatagta tcttacagga tgttaggatt tcatctgatg agagttatat agttttggtt
     8221 gtatcctcac tgcgtagcac taatttaatt ggaataaaaa aatatactat ggaagagtta
     8281 tttatcattg aagatatttc agtagaaagt tcgttctatt tgggtaaatt cggtgttatg
     8341 tatactcgct ccaaagagta cgggaggcca agtaagttat tctataaatc ttttgatagc
     8401 tttacagaag aggaactgtt tgaagaaaac gaatgctctt ttcgattaaa aatagtccac
     8461 attgatagca ataattgttt tgtaaagtca gtagactttc agaaaggcag gatttttcta
     8521 tacagtttcg accggacggg ttttgttaga cactcttaca cagaaacggt agccccaaca
     8581 cctagagata tcgctctatt tagtacagaa aaagcacagt actttcttgg gctctcttca
     8641 actgaagaaa agaaagatca actaattcta agggaaactt cttcgggaga cagagtttct
     8701 attactatac catatcaaga tagggctaga agagttcact gtataggacg ttatatcctt
     8761 ttagactgtt caaacgcagc gaattccgtc ttttatcttg ctacatttaa aaataatagt
     8821 ttgagggagt tgagtgttaa taagataaca tttgatgaaa agacaacact ttatgaaaat
     8881 tcattttctg atcgtgttct tctgttttta gagaggagaa ctttttacga aaaaatactt
     8941 agttttgatt taatagaaaa tacattaaaa actgaatttg aaagacccat cataaaatcg
     9001 aataatacta aatatttttc taaggtgatt tggactaaaa aagacagtta tgatgtaagc
     9061 ataccgattt ctttattttg gaaaagtgaa gatacggatg agctcccaag aagaaaaaaa
     9121 tgtattctaa gtgtctatgg ggcttatggt aagaatgata attctgattt agatgaaatt
     9181 atgttatcta taatagatgc aggttttatt tatgctatag ttcatgtaag aggtggaggc
     9241 tatttgggtg gtgaatggta tcgctcagga aaggcgttaa acaaatggaa ttctatcaga
     9301 gattttattg agggagtaaa ttatttaagg gaaaatgatg taattgacag taagcgatta
     9361 ggtttaataa cttctagtgc aggtggaata attgctggtg cggtgttgaa cgaggaaaaa
     9421 aatttattgc aaagcattct cttattttcg ccatttataa atccttatga tacacttcag
     9481 aatccaaatg atcctctttc taagaccgaa atagcagagt ggggagatat tagagaccct
     9541 gaagtaaagg cttatataaa gtcatattcg cctatgcaaa atattgaaaa ggcacgagac
     9601 tcaaatactg ttatagttaa tattttgggt gagaaagacc catatattaa taataacgaa
     9661 gtgatagagt ggtcaaagaa attaaattct attggagtta aaagtttgtt gtatttaaac
     9721 aaagcagctg gtcatggagg ttttactcca tcagatgttc tcttaatgat tgatacttta
     9781 aattatttct ttgaagaagt gggaaggaat aacttatgaa ttatttaaaa tttataaaaa
     9841 agactaaact tatattaatg gggattttaa tatttctatc ttcgtttaat ggtgtcttgc
     9901 tctcaggaat tattgtatat gcaggtagtt taaatcagac ttcctcattt tctgacgttc
     9961 taagatttgg tgctataagt attctgggtt ggtcagcaat ctatatatca aattactatt
    10021 tagaagtaac ggaagcatca ataacgaaag atataaatgt aaaaattaaa caaggatatt
    10081 ttagagaaca gtatctttct tctgaaatgg ttaaagatta ctcatctatt atttcagttt
    10141 tgtcaaatga tttgagatta atcgaagaaa actattttag acaaattttt gaaataattt
    10201 cttcaatatt gttgttcatc gtctctctaa gttttatgct ttatttaaac ttcctagttt
    10261 caataatatt tattgtatta tcagcattgc cgattatagt acctgtcttt atgaagaaga
    10321 tgttgtctaa ttcagctaat gagtactcta acagcaatgc agagtatact cacataataa
    10381 aagaaatttt taatggtttt aagacattaa aatcttattc tgttactaaa gaaataatta
    10441 gtttgtcgga taaaaagttg gataaactag aagattctac ttttaatttg aaacgatcag
    10501 aggttctttc aaaattggtt gcagtactaa tttcaggttt ttgctttcta gttcccttgg
    10561 ttgtaggatg ttattttgta atttatcata aaagcctttc ttttagtgaa ctgataggta
    10621 ttttcttagc aaacgataaa gttttagggc cgatacaatc aattgcctat tcattaaata
    10681 agataaatac aaccaaagat ttaaggaaac cgtttttaaa atacttaagt ggagagaaga
    10741 attttataga cgctgaacat gataataacg gactgtatac ttcatcaata gatgagatac
    10801 acatgaaaga tgttgtatat tctattacac cagaaaataa attaagtatt gacttctcat
    10861 ttaagtcacc atttagggta ttattaacag gaacttctgg tagtgggaaa acaacgattt
    10921 taaatttaat taatggttct ttaaagccac aaaaaggtta tgtaaatttg ttatcacatg
    10981 ggaaaaagag ttcagattca ataccaacag ttgatcagac accatatatt tttgacacta
    11041 ctattcgtga gaacgtaact ttatttcaaa atgaatattt ttcagatgat cagataattg
    11101 aggtgttaaa aaaggtaaat ctatatgaag aattagaaaa gatagatata ctaaattatc
    11161 aatgtggtga aaatggtagt aatttgtctg gaggtcaaaa acaaaaaata gctttagcta
    11221 gagctctgat tagaaataat aaagtgtact tatttgacga aatatcagct aatttagata
    11281 atgataattc aaattccata catgatattc tgttcaattt aggtatttca tttattgaag
    11341 tttcacatca ttatgactta aatgacaaga gatacactga tatatataaa ttggaaaatg
    11401 gaacactttt caaaattaag tgattggagg caagaatatg gataaagatt atatattaaa
    11461 agtgaaaggg ctgtatcatc aatttttact aggaaataat aaaacgttgc aagtgctgaa
    11521 aaatgtttct ctttctgctt cgagaggaga atttataagt attctaggaa ttagtggttc
    11581 tggaaagtca actttattaa aatgtatttc tagtttgctt gaaccaacaa gtggggaagt
    11641 aattttaaat ggaatcaacc cctataaaat cagaaatgca aaattgtcaa gtataagacg
    11701 taacgaagta tcttttatat ttcaagcata caatttaata ccttccctgc cggtaataga
    11761 aaatatagca cttcctttgc gattatcaca aaaaaaatta actattaaaa atgtagaaaa
    11821 cttactcaaa agaatgaagt ttaatgctgg cttaaacgat tttgttggaa ctctgtctgg
    11881 tggagaacaa cagaaggttg ctatagctag agcggttatt gctgatagtg atataatatt
    11941 tgctgatgag ccaactgggg ctttagacag cgtttctcgt gaagtaattt ttgaattatt
    12001 gagagagtta gtaggggcgg gtaagtgtgt aattatggta acgcacgata tagaattggc
    12061 ctcgaaaact gatcgtgcat taatattgaa agatggaaaa attttcaaag aacttcatag
    12121 acctagcggg gaagagttgt ataaaatctt agaggtacaa tcaactacgg aggaatagag
    12181 atgctcagat tagtttacta tcaattttta cataataaga aacaatggtt aggcgtttca
    12241 ccagtaattt ttgtttcgag tttagttatg ggattggctg ttaatggggt aattaatgtt
    12301 gagaataatt cgcaagtatt tgtcggactt ccagatccta aaccaatttt tatgtttccg
    12361 atagtattcg gaggagtaac attattcttt gtgctctcta acataataaa tatgttggtt
    12421 gaaattttta gagatgatta cgaacttctg gaggtgttgg gagcaagtct ccttcaacta
    12481 tcatttcttg tggggggaca gatttttatc atttcctcga ttattagttt tattgcatat
    12541 ctatgctcta tatttgttac gtcaaattat tattattttt tacaatactt tttcggggaa
    12601 aatatattac ctgatatcca atttcaaacg agtgctgttg gatgtatcat tacagtagtg
    12661 ttgatttcat ttttagcctt tctaagtggt tgcttttata cgttcaagaa gattagaaat
    12721 aggaagagtt ctaaaataag gcatgttctt tcaatagtaa aaagaatact gctattggct
    12781 ggttttagtg ttatctggtt gctttctttg caacaaattt tccaagatag cacaatttta
    12841 gcgaaggccc agataatatt caatattgta atcttagata ttgtgattat ttatcaatta
    12901 tctcctttta tacagtcatg ttttatcaaa ctactttcta taattatatt tagaaataat
    12961 tttatgttca ttgcttcgaa gtggaattta ctatatcgta agccttatat aaaatctatc
    13021 agtgctgcaa ttacaggagc tatattacta atttctagtt ttcaaatgat ttctcagaat
    13081 atactatctc aatttcaaga tgacagtgat ttagagctaa aagtggcatt tattgtctat
    13141 gtaggagcac caattttgat agtacttgca aatattattt caattgcatt tttgtcatcg
    13201 catcaagaaa ggattgagat tcagcaattt gaaattttag gaacttctaa ttaccagatg
    13261 gttaagatta aagttggtga ggctatattt ttgacatttg ttacttcatt aattgcattt
    13321 ttacttaaca ttaaaattat ggctttaata tactactctt tagaggatgt tttaatagat
    13381 gatatgaatc ttttggggtt aatacttcca aattttatag tgtctattat tttatttatt
    13441 ttaatattta ttactaaaag ttcctatttt atctttaaga atgcaaaaat tatttcttaa
    13501 aaatttgtaa gttttcgcta tataaaatag ttaaatctat tttgtatcat tgcttgcatt
    13561 ttactggtgg agagaatata atgagggtgg ataaagtact taatcccaaa aatttaaata
    13621 ggaggagcta gctatggcag aagaagtatt aaatcttcaa ttagtatctg ttcaagttga
    13681 cgaaacagat gaagttgatg gaatgcgatt tagtacattc agtacaaacc gttgcggtaa
    13741 ctggagtgct tttagttggg aaaattgtta attcatttaa attgtaaact ttagggattc
    13801 tctgaagtta tggatgtcgt tccaatatgt gtacgttgga atgttagtgc ttatatgggg
    13861 ggaacagaat cctctcttga ttgaagacaa gttagccatt aggctggttt gtctctttgt
    13921 caactgtagt gggttgatat aatagtatta gtgagtggga taaaagtttc atttagttta
    13981 ttcagtacaa atttaacggg tcaagattta ttgaactgca ccccaatagt tagacagaa
//
LOCUS       DAVBBO010000057        13741 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ST1
            SAMEA2066453-rid20184263.denovo.057, whole genome shotgun sequence.
ACCESSION   DAVBBO010000057 DAVBBO010000000
VERSION     DAVBBO010000057.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2066453
            Sequence Read Archive: ERR351777
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 13741)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13741)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980402.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980402.1
            Genome Coverage       :: 176x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:17:33
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,141
            CDSs (total)                      :: 2,104
            Genes (coding)                    :: 1,953
            CDSs (with protein)               :: 1,953
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 16S)
            partial rRNAs                     :: 1 (23S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 151
            CDSs (without protein)            :: 151
            Pseudo Genes (ambiguous residues) :: 0 of 151
            Pseudo Genes (frameshifted)       :: 73 of 151
            Pseudo Genes (incomplete)         :: 76 of 151
            Pseudo Genes (internal stop)      :: 40 of 151
            Pseudo Genes (multiple problems)  :: 32 of 151
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13741
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2066453-rid20184263.denovo.057"
                     /strain="ST1"
                     /db_xref="taxon:1313"
     gene            2..1242
                     /locus_tag="VQU30_001768"
     CDS             join(2..341,341..1242)
                     /locus_tag="VQU30_001768"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611423.1"
                     /ribosomal_slippage
                     /note="programmed frameshift; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
                     /protein_id="HET2447831.1"
                     /translation="MVKLIDRYGIEIVKKGKNRHYSSKLKQEMMDKALLEGCSQRSIS
                     LDYALPNQGMLSFWPAQYKKNGYTIVEKTRGRPAKMGRKRKKTWEEMTELERLQEENE
                     RLRTEVAYLKKFKRVRGKGRSPRARKAETVREMVSGGFRLDFLLETARLARSTYYYQL
                     KQLDGVDKDKEIKTEIQGIDNEHKGNYGYRRIHLELRNRGFVVNHKKVQRLMRILGLT
                     ARIRRKRKYSSYQGEIGKKAENLIQRQFEASRPMEKCYTDVTEFAIPNSTQKLYLSPV
                     LDGFNSEIIAYHLSTSPNLEQVKSMLEQAFTEKYYENTILHSDQGWQYQHDSYHRFLE
                     SKGIQASMSRKGNSPDNGMMESFFGILKSEMFYGYEKNFRSLENLEQAIVDYIDYYNN
                     KRIKVKLKGLSSVQYRTKSFG"
     gene            complement(1477..2085)
                     /locus_tag="VQU30_001769"
     CDS             complement(1477..2085)
                     /locus_tag="VQU30_001769"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001165927.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF624 domain-containing protein"
                     /protein_id="HET2447832.1"
                     /translation="MQIKFIDKVSNLIMLNLLYVASVVTVIAIGSGESALIATLIKIV
                     RHEESYPYRDFANSFFKDYWKNLGAALISNLPILILLFSLFFLPYIPLPIYIISILRH
                     IGVIYIILHLIATTFLIPLIGRYNNTLKNSLHNSIMLAYKHFFIAVLIRIIEIIPVLL
                     FFILQNQLLVWITLMIFILPSITKYANAFLYNFIFSKYEKLN"
     gene            2251..2421
                     /locus_tag="VQU30_001770"
                     /pseudo
     CDS             2251..2421
                     /locus_tag="VQU30_001770"
                     /inference="COORDINATES: protein motif:HMM:NF013577.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
     gene            2410..3021
                     /locus_tag="VQU30_001771"
     CDS             2410..3021
                     /locus_tag="VQU30_001771"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001821036.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HET2447833.1"
                     /translation="MTKDILELESQKMSSDTFIDEIKNNYLSIVESTRKLIDGRQIEL
                     AIKLIREANQILMIGVGSSGNAAREFESSLLRIGIISKTVIDTHFQLMHTALLKDNDL
                     IIAFSLSGSTKEVEETLLNAKRKNVKIISITNYSSRNIAKLSDCVLLTSKKESYLEGG
                     SLMAKASQLFIIDVICTRLSLINYEDTICKKEEIASLLSNKVE"
     gene            3738..4424
                     /locus_tag="VQU30_001772"
     CDS             3738..4424
                     /locus_tag="VQU30_001772"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000448315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmannosamine-6-phosphate 2-epimerase"
                     /protein_id="HET2447834.1"
                     /translation="METKKIKNLKGQIIVSCQALEGEPLYTPNGGVMPLLAKAAFQAG
                     AKGIRANSVRDISEIKEEVDLPIIGIIKRDYDGFEPFISATMKEIDELVSEGVDILAL
                     DCTNRSRPGYDNITDFIHDIKVKYPNQLLMAAISTFEEGKVAAESGVDFVGTTLSGYT
                     PYSPKKDNPDFELVERLVKELDVPVIAEGRISTPEQARKMLDLGAYAVVVGGAITRPL
                     EIAKKFIEVV"
     gene            4425..5357
                     /locus_tag="VQU30_001773"
     CDS             4425..5357
                     /locus_tag="VQU30_001773"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001071049.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HET2447835.1"
                     /translation="MNQEILKKSKIQLTVEHIQKYWILYLMMIPATVLLILFTYGPMY
                     GIIMAFQDFTVFKGYTGSPFVGLKHFQRLFSDPLFYRLFKNTFMVGVLDFLFFFPAPL
                     IFALILNEVRKVRFKSVVQSISYLPHFIPLVVMVGIIFELFGSYGIINSLLSSLGMEP
                     ISFFTKSEWFLPLYIGSGVWKTIGWGSIIYMGALTNIDSTLYEAADMDGANRWHKMWH
                     VTLPSLRPTVVTLFILNAGGIMQVGFEKVFLMSSPATYEVSDVLSTYVYRQGILNSDF
                     SYSAAVGLFNNIVALLFVLLANKIAKKLGEEGIV"
     gene            5368..6297
                     /locus_tag="VQU30_001774"
     CDS             5368..6297
                     /locus_tag="VQU30_001774"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000577774.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HET2447836.1"
                     /translation="MIFSKNTKKSNRDKETFVDYLFIFILIIITLLMLYPLWWVVMTS
                     LSEPVWLSKNVVKLFPLKIDITAYKFIFGDSKLWQAYGNSVLYAALSTIVSVAVCSMY
                     AYPLTIPEIRGKKFWNTLILIPMFFSGGMIPLYIQVANLGLLNTAWALVLPGAVSTYY
                     IILFRTQFKSIPMELRESARIDGASEFRIFWNLVLPLSKVIFMIIALYCIVGSWNSFT
                     PPLLYLNDDTKMPLSIYLRNLVVTNTTDTAELSLSAGNTYYQQIAAQGGGIGMRIAIK
                     MGTIVVSVIPIMMIYPFIQKHFVKGILLGSVKG"
     gene            6311..7750
                     /locus_tag="VQU30_001775"
     CDS             6311..7750
                     /locus_tag="VQU30_001775"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001178946.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2447837.1"
                     /translation="MQNLKKYLLLDSGLVVGYTLENAQLKLNKLKKDTENNPLFGEEY
                     FAENPKLWEVRFDNSYPNVIYDKELKLYRCWYQTFVSDEASEETPLAERGEKEYIVKS
                     SRMTALCYAESKDGVKWEKPNLNLVKFKGSKDNNIVLMHAHGAGIMLDEQELDPKKRY
                     KLVSKLEFSPNLHYMVVVFSEDGIHFDEPIPWKKWNPAADSHNFPFRDPKTGKYAVIT
                     RTWANNVRLSAITFSDDFINWSEPKEILRGDGFEDQIYSMPVISYADIYLGFASMYHE
                     GDTLNENYDKVDLELKFSANLEQWDSVCKGDYLIERGGGVYPQNADFDASCIFTAAPI
                     IEDDKIWFYYMGGNGNHTGFRESSLARGYIKKDQFAYYTNKREGIPAKISTVSFQTYD
                     DEIYILADIPENGYIKVAVGTKYGNAYSDFGQEDISLVQVSDGKYKLEFNKKSILDLG
                     NSPVAFKFEIENAKLYGIEGSIQQHYLKY"
     gene            7819..9396
                     /locus_tag="VQU30_001776"
     CDS             7819..9396
                     /locus_tag="VQU30_001776"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000239902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HET2447838.1"
                     /translation="MVKLNKVLKGSVAFLSASLLLAACGNNANSKPAEKTADGKTKIS
                     FLSTWQINDVRPPKDETLVGQWLEEQLGIDIDLVTIPGEGVSSKVNSLITSNQLPTVL
                     LTTGDKSDIAGINKLGKQGAFLDLSQHMDKLPNYKKYLEKNNALAQIEDDEKHIYAFT
                     KFFTDENIMYTTPILRKDLLVGSEFEDLSKIKTVDDYTKVLKYLTEKQGSPAFIQRNG
                     YEGFMKRVTPLWNLSHRTYYDYESDSYKHPVEQPQLKQFVEWLKELRKDNVLHPDWAV
                     MKDETWEGLLASNKGSFTVDRMNIIGDNNFDKSFDWQPLVYPEINGKRYLQPKTPYIS
                     DSGWVINANAPKEEIDKALEFFNFLYADENQEKLAIGFEGKTFTRENPNTQAGIKWLI
                     QIYGENAGNDKAELLFKHGNQAFTRVQTKLDIEAQPGTFPKVMYDQVDKIKKDLGGFR
                     PDTPVLSFTTEELDVLTKSEAGLNTFFDENIIKFIEGQRDMSEWDSFINEAKSKDLDK
                     VTKVYNDAYKRVKDRMK"
     gene            9456..10916
                     /locus_tag="VQU30_001777"
     CDS             9456..10916
                     /locus_tag="VQU30_001777"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000272432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HET2447839.1"
                     /translation="MYDVVIIGAGSSGALAAIASGRLGLKTCLIEKGSRIGGVPINTL
                     MGSFANLYFDDSGRVNASKIVGELIERIIKKGGTVFNSMEELMNVNDFYQITIPYQPE
                     VYESVLTDMLIESKVDILLNVEVNNIIYDSKNIKSLEILSNQEVKLIDSKVFIDATGN
                     ATIASASGADVYEKNSSYGCLMRVGGVDISKTIEHIEKTKQWNYIEGYNQWLEEVLAN
                     RKYRATGAVLKDPVSYDHAPMLSKDDHFMNDEKWNYIKERWEKFRFIYTLEVSLFRNE
                     LKKAVESGDFNFEIYHDDKSGVTMNGDGISYGSWGQNVALINVAKAFGFNPKYMEDES
                     HANILSRKYNLTFLSFLKKYVPGFENSFILDQGTRATNRSCRHIDNSSMMDEILDFPM
                     YTFKTMYSYQTPKEITYKSIVGGKLNNLFVIGKGAYQSESFRSQISCMLMGISSAAAA
                     KTIIEDKSNTLNINRDLFKSNLDILFTWEFSNWITD"
     gene            10938..11393
                     /locus_tag="VQU30_001778"
     CDS             10938..11393
                     /locus_tag="VQU30_001778"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001000318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HIT domain-containing protein"
                     /protein_id="HET2447840.1"
                     /translation="MNDTNKNQYFVYEFDTSFVEMSYSQFFEGYCILFSKEPYPSLSD
                     MPMEFRKEFLMEMSILGDAMLEVLNAYRINYDILGNSTPVLHAHLFPRYMWEEEERRK
                     TVVHRYDSSVFSNPEFEFTIEKHGPIIKKLRSAIDRHYREYQQLLDDSN"
     gene            11480..11885
                     /gene="cdd"
                     /locus_tag="VQU30_001779"
                     /pseudo
     CDS             11480..11885
                     /gene="cdd"
                     /locus_tag="VQU30_001779"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000221146.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="cytidine deaminase"
     gene            11898..12347
                     /locus_tag="VQU30_001780"
     CDS             11898..12347
                     /locus_tag="VQU30_001780"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000424229.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhcH/YjgK/YiaL family protein"
                     /protein_id="HET2447841.1"
                     /translation="MELVEFKNGHVNTVHEHIAITKVKEFLNNHDILKDKGGIHKIST
                     DFFYNIIDMETTTEENRPWESHKEYYDVHYLLNGEETILYNFLSQMELSEYKVDDDWQ
                     QMNGTALFSIKLKKDMLLLLEPNDAHRTGLLVEEPLNIKKVVFKVKI"
     gene            complement(12459..13018)
                     /locus_tag="VQU30_001781"
                     /pseudo
     CDS             complement(12459..13018)
                     /locus_tag="VQU30_001781"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611577.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS630 family transposase"
     gene            13287..13741
                     /locus_tag="VQU30_001782"
                     /pseudo
     CDS             13287..13741
                     /locus_tag="VQU30_001782"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="frameshifted; incomplete; missing C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
BASE COUNT         4865 a         1850 c         2538 g         4488 t
ORIGIN      
        1 catggtgaaa ttaattgacc gttatggcat agaaatcgtt aaaaaaggga agaatcgtca
       61 ctattcttct aaattgaaac aagaaatgat ggataaagcc ttactggaag gttgttcaca
      121 aagaagtatt agtcttgatt atgccctccc aaaccaagga atgctttcat tttggccggc
      181 acaatacaag aaaaacgggt atactattgt tgagaaaaca agagggagac cagctaaaat
      241 gggacgtaaa cggaagaaga cttgggaaga aatgacagaa ctagaacgac tccaggagga
      301 gaatgaacgc ttacggactg aggtggccta cctaaaaaag ttaaaagagt tagaggaaag
      361 ggacgaagcc ctagagcgag aaaggcagag acagttagag aaatggtttc aggaggattt
      421 cgactagatt ttcttcttga aacagcacgt ttagctcgct cgacttacta ttatcagttg
      481 aaacaactgg atggggttga taaagataaa gagattaaaa ccgaaattca gggcattgat
      541 aatgaacata aaggcaacta tggctatcgt cgaatccatt tagaactaag gaatcgtggt
      601 tttgtggtca atcataagaa agttcaacgg ttgatgagaa ttcttggttt aacggctcga
      661 attcgccgta aacggaagta ttcttcctac caaggagaga ttggcaagaa agcagagaat
      721 ctcattcaac gccagttcga agcatcgagg ccaatggaaa agtgctatac agatgtgaca
      781 gagtttgcca ttccaaatag cacacagaaa ctctatttat caccagtttt agatggtttt
      841 aacagtgaaa tcattgctta tcatctttct acttcgccaa acttagaaca agtgaagagt
      901 atgttagaac aggcctttac agagaaatac tatgagaata cgattctcca tagtgaccaa
      961 ggctggcaat accaacacga ttcttatcat cggttcctag agagtaaggg aattcaagca
     1021 tccatgtcac gcaagggcaa cagcccagac aacggcatga tggaatcttt ctttggcatt
     1081 ttaaaatccg aaatgtttta tggctatgag aagaacttta gatctttaga aaaccttgaa
     1141 caagctattg tggactacat tgattactac aacaacaaac gaattaaggt aaaactaaaa
     1201 ggacttagtt ctgtgcagta cagaactaaa tcctttggat aaattatttg tctaattttt
     1261 tggggtcagt acagtattaa ataccatgat cttatgcgtt ttataataaa aaatctgttc
     1321 ttgttttatt tttagaaaat ttactaaaga ctaaaaatat tatgaataat ttaaaaaata
     1381 gtcaggttat atagtttttt gaaattaaaa ttattttatc gttgaaatta gttaaaaatt
     1441 tttataaaat caagatgcaa ggctatgaga tgttctctag tttaattttt catacttcga
     1501 gaatataaag ttatataaaa atgcattagc atattttgtt attgagggaa gtataaaaat
     1561 cattaaagtt atccaaacta gtaattgatt ctgtaatata aagaagagta gaactgggat
     1621 aatttcaata attctaataa gaacggcaat aaaaaaatgt ttataggcta acatgattga
     1681 attgtgtaga gaatttttta aagtgttatt atatctaccg attaaaggaa ttagaaatgt
     1741 tgttgctatt aaatgaagta tgatatatat tactccaata tgtcgtaaga tagaaatgat
     1801 atatataggt aatggtatgt agggtaggaa gaacaaactg aataataaga ttaaaattgg
     1861 taaattagat attaatgctg ctcctaaatt tttccaataa tctttaaaaa aactgtttgc
     1921 gaagtctcta tagggatagg attcctcgtg tcgtacaatt tttattagag ttgctattag
     1981 ggcactttca cctgatccga tagcaataac tgttactact gacgctacat agagtagatt
     2041 taacattata agatttgaaa ctttatcaat aaattttatc tgcatcttta actcctgctg
     2101 tttttatact tataatatca catcatttga gtttcatcaa ctttgaatac attaagaaag
     2161 aatataacta tgaggaaagg aaaaaattat tatgaataaa tccaaaaaat ataaagaaag
     2221 aattcattat gaatacgata atcttactaa atcagagaaa aaattgctga ctatatttta
     2281 gttagagata gtgaaatagt ttatgaaacg tcttcagaaa ttgttagtaa agtaaaagtt
     2341 ggagagggaa ctcttaatcg attttgcaaa aagattggat actctggttt tcaggaacta
     2401 aaattaaaaa tgacgaaaga tatattagag ttagaatctc aaaaaatgag tagtgacaca
     2461 tttattgatg aaataaaaaa taattattta tctattgtgg aaagtacaag aaaattaatt
     2521 gatggtagac aaatagaatt agctataaaa ttaataagag aagcaaacca gattttaatg
     2581 attggtgtgg gttctagtgg aaatgcggct agagaatttg agagtagttt gttaagaatt
     2641 ggaataataa gtaagacggt aattgatacc cattttcaac tcatgcatac tgcgttattg
     2701 aaagataatg atttgataat agcgtttagt ttatctggtt ccacaaaaga agttgaggaa
     2761 actttattaa acgcaaaaag aaaaaatgtt aaaattattt caataacaaa ttattcgtcc
     2821 agaaatatag caaaattatc tgactgcgtt cttttgacat caaaaaaaga atcttattta
     2881 gagggtggta gtttaatggc taaggcttct caactattca taattgatgt aatatgcact
     2941 agactctctt taataaatta tgaagatact atatgtaaaa aagaagagat tgcttctttg
     3001 ctgtcaaata aagtggaata aatcaataat ttttaaattt taataaaaat tttttaaaat
     3061 aaattaaaaa acgatcctaa aagggtcgtt tttttgctaa agttttaaaa ataaacaata
     3121 attaagatta tagtgcgttg aatctatatt aggacataac aattcttaaa tcattgttag
     3181 aaattagttt gaattttcca atcaatttgt tcgattttta catcattgca ttatatcacg
     3241 tgactattaa ccttgttttc tcctaaaatt gattttcttc ttttcttatc ttgtccactc
     3301 gaaacaagta ttgtaagaat ttgattattt ttgaaagtac ttttaatata tttgagatag
     3361 ttaaaaaaga tttgaaacta aattccaaat tagaaaaaga cttgaaatgc taaaaaaaaa
     3421 aagtatactc taattgaaaa cggtaacaaa actaatttag agaatgaaat atagagtatt
     3481 tctctcttaa aagtttttgg tgaaacgaga tgtagaaagg agatttagcc aaagagtcta
     3541 ttagtgctag aataatagat tagaattata gtgtattgaa tctataacag tacgccttaa
     3601 atgctaaaat atttctataa attaatttaa ctttcctgat agggctgttc atatcttatt
     3661 tcaattcact atataaataa aattgtagta gatgttattg aattagtaaa aaaaataaaa
     3721 aaacggaggt tttctgaatg gaaactaaaa aaattaaaaa tttaaaaggt caaataattg
     3781 tttcctgcca agcgttagaa ggagagccac tttatactcc aaatggagga gtgatgccgt
     3841 tattagcaaa agccgccttt caagcaggcg ctaaaggtat tcgtgctaat tctgtccgcg
     3901 atatttcaga aataaaagaa gaagttgact taccaattat aggtatcata aaaagagatt
     3961 acgatggctt tgaacctttt atttcagcaa ctatgaaaga gattgatgaa ttagttagtg
     4021 aaggagtaga cattttagct ttggattgta ctaatcgttc aagaccaggt tatgataata
     4081 ttactgactt tattcatgat attaaagtca agtatccaaa ccaattatta atggctgcta
     4141 tttctacttt tgaagaaggg aaagtagctg ctgaatcggg agtagatttt gtgggtacga
     4201 cattatctgg ttatacacca tatagcccta aaaaagataa tcctgatttt gagttagttg
     4261 aaagattggt aaaagagctt gacgtaccag ttattgctga aggaagaata agtactccgg
     4321 aacaagctag aaaaatgtta gatttaggtg cttacgcagt ggttgttgga ggagctatca
     4381 ctcgtccttt ggaaatagcg aagaagttta ttgaggtagt ttagatgaat caagaaatat
     4441 taaaaaagag taagattcaa ttgacagttg aacatattca aaaatattgg attttatatt
     4501 taatgatgat tccagcaact gttctactaa ttttatttac gtatggacca atgtacggca
     4561 ttattatggc ctttcaagac tttactgtct tcaagggata tactggaagt ccatttgtcg
     4621 gtttaaaaca ttttcaaaga ttgttctcag atcctttgtt ttatagattg ttcaagaata
     4681 cgttcatggt aggggtttta gattttttat tctttttccc agctccgctt atttttgcac
     4741 tcatattaaa cgaagtcaga aaagtaagat ttaagagtgt agttcaatct attagttatc
     4801 ttcctcattt tattccccta gtggttatgg ttggtattat ttttgaacta tttggttcat
     4861 atggtattat taacagttta ctttcatcac ttggaatgga gccaataagt ttctttacaa
     4921 aatctgaatg gttcttgcct ctctacattg gttcaggagt atggaaaaca ataggttggg
     4981 gttctatcat ttatatggga gcattaacca atatagattc aactttatat gaagcagcag
     5041 atatggacgg ggctaataga tggcacaaaa tgtggcatgt aactctacca agtttaagac
     5101 ctacagtagt tactttgttt atactaaatg ctggtggtat catgcaagta ggatttgaaa
     5161 aggtattctt gatgtctagt cctgcaacat atgaagtatc tgatgtatta tctacttatg
     5221 tttatagaca aggtatttta aattctgatt tcagttactc agctgcagta ggattattta
     5281 ataacatagt agctttgtta tttgttttat tagctaataa gattgctaaa aaacttggcg
     5341 aagaaggaat tgtataaggg gggtaaaatg attttttcaa aaaatacaaa aaagagtaat
     5401 agagacaaag aaaccttcgt tgattatctc tttatattca ttttaataat aataacctta
     5461 cttatgttgt atccattatg gtgggtagtg atgacgtcac tttcagaacc agtttggcta
     5521 tctaaaaacg ttgttaaatt atttccctta aaaatagata ttactgcata taagtttatt
     5581 tttggggatt ctaaactatg gcaagcatat ggtaatagtg tattgtatgc tgcactatct
     5641 acaattgtta gtgttgcggt atgtagtatg tatgcctatc cacttacaat tcctgaaatt
     5701 aggggtaaaa aattctggaa tactcttatt ttgattccaa tgttctttag tggaggaatg
     5761 atcccgcttt atatacaagt tgcaaacctc ggtttattga atactgcttg ggctcttgtt
     5821 ttacctggtg ctgtttctac atattatata attttgttta gaacacagtt taaatcaatc
     5881 ccaatggagc ttcgtgagtc tgctagaatt gatggggcaa gtgaatttag aattttttgg
     5941 aatttagtat taccattatc aaaagttatt ttcatgatta tagcacttta ttgcatagtt
     6001 ggttcatgga atagttttac tcctccatta ctttatttga atgacgacac taagatgcct
     6061 ttatctattt atttgagaaa tttagtcgtt acaaatacaa ctgatactgc tgaattatca
     6121 ctttctgcag gtaatacata ttaccaacaa attgctgctc aaggtggagg tattggtatg
     6181 cgtattgcta ttaagatggg tactattgtt gttagtgtta ttccaattat gatgatttat
     6241 ccatttattc agaaacattt tgttaaggga atcctgctag gttctgtgaa aggttaataa
     6301 ggtaattatt ttgcaaaatt taaaaaaata tcttttatta gatagcggtt tagtagttgg
     6361 gtatacatta gaaaatgctc aattaaaatt aaataagcta aaaaaagata ctgaaaacaa
     6421 tccactattt ggtgaagagt attttgccga aaatcctaaa ttatgggaag ttcgttttga
     6481 taattcatat ccaaacgtta tctatgataa agaattgaaa ttatatagat gttggtatca
     6541 aacatttgtt agtgatgaag caagcgaaga gactccttta gcagaacgtg gagagaagga
     6601 atacattgtc aagtcatcta gaatgacagc actttgctat gctgaaagta aagatggagt
     6661 aaaatgggaa aaaccaaatc tcaatctagt aaaatttaaa ggttcaaaag ataataatat
     6721 tgttctgatg catgcacacg gtgcaggtat catgctagat gaacaggagt tggatcctaa
     6781 gaaacgatat aaattagttt caaaattaga attttctccg aatcttcatt acatggttgt
     6841 tgttttttca gaagacggta ttcattttga cgaacctatt ccatggaaaa aatggaatcc
     6901 tgcagcagat agtcataatt ttccatttag agatccaaaa actggtaaat acgctgttat
     6961 tacaagaacc tgggcaaata acgtacgtct aagtgcaatt actttcagtg atgattttat
     7021 taattggtca gaacctaaag aaatccttag gggagatgga tttgaagatc aaatttattc
     7081 tatgccagta atttcatacg cggatatcta tttaggtttt gcttcaatgt accatgaagg
     7141 cgacacttta aatgaaaact atgataaagt agacttagaa ttgaaattct ctgctaattt
     7201 ggaacaatgg gatagtgtat gtaagggcga ctatctcatt gaaaggggag gtggagtata
     7261 cccgcagaat gctgattttg atgctagttg tattttcacg gctgctccaa taattgaaga
     7321 tgataagatt tggttctact atatgggtgg aaatggtaat cacactggct tccgagaaag
     7381 ttcattagct agaggatata ttaagaaaga ccaatttgct tattatacta ataagagaga
     7441 aggaattcca gctaaaatat ctacagttag cttccaaact tacgatgatg aaatttatat
     7501 cttagctgat attcctgaaa atggttatat taaagttgcg gtaggtacta aatacggtaa
     7561 tgcttattca gatttcggtc aggaagatat ctctcttgtt caagtttccg atggtaagta
     7621 taagttggaa tttaataaaa aatctatctt agatttaggt aattctccag ttgcgttcaa
     7681 atttgaaatc gagaatgcaa aattgtatgg tattgaaggt agtattcagc aacactatct
     7741 caaatattaa ccagaataat tcgttaacaa ataatctcta tattagtgga gatagatata
     7801 taaaatggag gtcttattat ggtaaagctt aataaggtat taaaagggag tgttgcattc
     7861 ctgagtgcaa gtttattgct agcagcttgt ggcaataacg ctaattcaaa gcccgctgaa
     7921 aaaacagctg atggtaaaac gaaaatttcg tttctatcta catggcaaat taatgatgtt
     7981 cgtccgccta aagatgaaac acttgttggt caatggttag aagaacagct aggtattgat
     8041 attgatcttg taactattcc tggcgaggga gtaagttcta aagtaaattc tcttattact
     8101 agtaaccagt taccgactgt tttgttgaca acaggagata agagtgatat cgctggtatc
     8161 aacaaacttg gtaaacaggg tgcattctta gatttgtcac aacacatgga caaactacca
     8221 aactataaga agtaccttga aaaaaataat gcattagctc aaatagaaga tgatgaaaaa
     8281 catatttatg ctttcacaaa attctttact gatgagaata tcatgtatac tacaccaatt
     8341 ctgagaaaag acttacttgt tggttcagaa tttgaagatc tttcaaaaat taaaactgtt
     8401 gatgactata caaaagtttt gaaatatttg actgaaaaac aaggttctcc agcatttatt
     8461 caacgtaatg gctatgaagg cttcatgaag cgagttacac cattgtggaa tttaagccat
     8521 cgtacatact atgactatga atcagattca tataaacatc cagttgaaca acctcaattg
     8581 aaacaattcg ttgaatggtt gaaagaatta cgtaaagata acgtacttca ccctgactgg
     8641 gcagttatga aagatgaaac ttgggaaggt ctattggctt ctaacaaggg ttcattcact
     8701 gttgaccgta tgaatatcat tggagataat aactttgata aatcatttga ttggcagcca
     8761 cttgtttatc cagaaattaa tggaaaacgt tatttgcaac cgaaaacacc gtacatttct
     8821 gattcaggtt gggtaatcaa tgccaatgca ccaaaagaag aaattgataa agcgttagaa
     8881 ttctttaatt tcttatacgc tgatgaaaat caagaaaaac ttgctattgg atttgaaggt
     8941 aaaacattta cacgtgaaaa ccctaatact caagcaggta ttaaatggtt gattcaaatt
     9001 tacggtgaaa atgctggaaa tgataaagca gaactgctgt ttaaacatgg taaccaagca
     9061 tttactcgcg ttcaaactaa attagatatt gaggcacagc caggaacatt ccctaaagtt
     9121 atgtatgatc aagtagataa aattaagaaa gatttaggtg gttttagacc agatactccg
     9181 gttctttcct ttacaactga agaattagat gttttaacta aatctgaagc aggattaaat
     9241 actttctttg atgaaaatat tattaaattc attgaaggac aaagagatat gagtgagtgg
     9301 gattcattta tcaatgaagc taaatctaaa gacttggata aagttacaaa agtatataat
     9361 gatgcctaca aacgtgtcaa agatagaatg aaatagacta aatggtagct ctctggtttt
     9421 tcagagagct actactgcct gagggggagt aagctttgta tgatgtagta attataggtg
     9481 caggaagttc gggcgcattg gctgcaattg cttcggggcg tctagggtta aaaacttgtc
     9541 taatagagaa gggaagtaga attggtggag ttcctattaa tacactaatg gggtcatttg
     9601 ctaatctata ttttgatgat tctggtagag taaatgcaag taaaattgtt ggggaattaa
     9661 tagaacgtat tatcaaaaaa ggtggtactg tctttaactc tatggaagaa ttgatgaatg
     9721 taaatgattt ttatcagatt acaattccct atcaaccaga agtttatgaa tcggttttaa
     9781 ctgatatgtt gattgagtct aaagttgata ttttactaaa tgttgaagtt aataatatta
     9841 tttatgatag taaaaatatt aaaagtcttg aaattttaag taatcaggaa gttaaattga
     9901 ttgattctaa agtttttatt gatgctacag ggaatgcaac aattgcttct gctagtggag
     9961 ctgatgttta tgaaaaaaat tcttcttacg gttgtttaat gagagttgga ggagttgata
    10021 tctcaaagac tatagaacat attgaaaaaa caaagcagtg gaactatata gaaggatata
    10081 atcagtggtt agaagaagta ttagcaaatc gaaagtacag agccactgga gcagttttaa
    10141 aagatccagt ttcttatgat catgccccta tgctttcaaa agacgaccat tttatgaatg
    10201 atgaaaaatg gaattacatt aaagaaagat gggaaaaatt tagatttatt tacactttag
    10261 aagtatcact atttaggaat gaattaaaaa aagctgtaga atctggggat tttaattttg
    10321 aaatttatca tgatgataaa tctggagtca ctatgaatgg cgacggtata agctatggtt
    10381 catggggtca aaatgtagca ttaattaatg ttgcaaaagc atttggattc aatcccaaat
    10441 atatggaaga tgaatcacat gctaatattc tttctagaaa atataattta acatttttat
    10501 cttttcttaa aaaatatgta ccaggttttg aaaattcttt tatccttgat cagggaacta
    10561 gagctactaa cagatcatgt aggcacattg ataattcatc tatgatggac gaaattcttg
    10621 attttccaat gtatacattt aagactatgt atagctatca aactcctaaa gaaataacgt
    10681 acaaatcaat tgtaggtgga aaattgaata atttgtttgt aataggtaaa ggtgcttacc
    10741 aatccgaaag ttttagatca caaattagtt gtatgttaat ggggatatca tcagcagcag
    10801 cggcaaaaac tattattgaa gataaaagca atactctaaa cattaataga gatttgttta
    10861 aatcgaactt agatatatta tttacatggg agttttctaa ttggattact gattaacaaa
    10921 taataaggga atattaaatg aatgatacta ataaaaatca atactttgtt tatgaatttg
    10981 atactagctt tgtagaaatg tcttattctc agttttttga aggatattgt attctttttt
    11041 caaaagaacc ctatccttct ttatctgata tgccaatgga atttagaaaa gaatttttaa
    11101 tggaaatgag tatattaggt gatgcgatgc ttgaagtgtt aaatgcctat agaattaatt
    11161 atgatatctt aggaaattca acacctgtac ttcatgctca tttatttccg agatacatgt
    11221 gggaagagga agagagaaga aaaactgtag ttcatagata tgattcttca gtttttagca
    11281 atcctgagtt tgaatttact atagaaaagc atggaccaat tattaaaaaa ctgaggtctg
    11341 ctattgatag acattataga gagtatcaac aattattaga tgattcaaac tgaactccac
    11401 attttcgatt agatttaata ccttgtatat tacaactagg ttgtggatga tataattttt
    11461 tgaaaaatat attttaggaa tgacttataa agcaattata tcagaggcta ttaaatcaat
    11521 ggccaaagct tatgctcctt attctgattt taaggttgga gctgcgttag taactgaaga
    11581 taaaaaattt tttctggatg taatatagaa aatgctgctt tttctcctac ttgctgtgca
    11641 gaacgagtat ctttttataa agctgtattt aaaggagaac gttcgttttc aagaacatgt
    11701 attgtaggtg gaaaaaatgg tatcttatca tcttttatag caccttgcgg agtgtgtcgc
    11761 caggtaatga tagaatttgt aatcctgatt catttgaagt tatattggct agtgatgttg
    11821 atacttataa agtatataaa cttaaagaac tactaccagt tagttttaat caagaaaatt
    11881 tataacagga gggaactatg gaattagttg aatttaaaaa tggacatgtt aatacggttc
    11941 atgagcatat cgcaataacg aaagtaaaag agtttctaaa taatcatgat atattaaaag
    12001 ataaaggtgg catacataaa atttctactg atttctttta caatataatt gatatggaaa
    12061 ctacaactga agagaataga ccgtgggaaa gtcataagga atattatgat gtccattatc
    12121 tgttaaatgg agaagaaaca attttatata acttcttgtc tcaaatggaa ttgtctgaat
    12181 ataaagtaga tgatgattgg caacaaatga atgggacagc tttatttagt attaaattaa
    12241 agaaagatat gttacttttg ttggaaccaa acgatgcaca tagaacaggc ctattggttg
    12301 aagaaccact taatattaag aaagttgttt ttaaggtaaa aatttaactg aaagtacttt
    12361 cggggattaa gaattttaaa atatttaaga aattgtattc taaagttcta aaattataga
    12421 tatttaattt aaagcttgtt aaaatagaat agtaacactc atctgctttc aaaaagcatt
    12481 ctattccatc tccgattaac gatggacttt atcacctcct tctccagtcc ttgtatgaca
    12541 tcttggagtt gattcatgac atcttccaaa gttcgaaagg ctttattctt aaatccacgt
    12601 ttatgaatct ctttccacac ttgttcgatg ggttcatctc tggtgtgtat ggaggaataa
    12661 atgcaaaacc aatattagtc ggagtcttta aggtacttga tttatgccat atagcattgt
    12721 ccataacgag taaaagataa tcatctggat aagcttgtga aagctcttct aaaaaggcgt
    12781 tcatccactc agtattacat ccaccagcta ttaagaaaaa tgattcgcct gtatgggcat
    12841 caacagctcc ataacaatag tgaaattctc gtatatagtg actatggaca tgtggaccta
    12901 ctcctattgg agaccaacaa gatcccagtt tactgattct accgaagcca gcctcatctt
    12961 ggtacatcaa gcgaacctta tgaaaacgtc tactggtttt aaagcgcttt cttttcttca
    13021 gttgatttca tatcactatt gtataatgct ttttgatttt agtctagtat aaatagcgag
    13081 aaatatctat cctatcttct agaatgtctt ccaaacgagg aaactctcgt aaacaaagag
    13141 gttttagagg cctatttacc gtggactaaa gttgcacaag aaaagtgcaa ataagaaatc
    13201 tccagattag gaactatccg tgagttctct agtctggaga tttttcaata gacttcctgc
    13261 gaaacaaaat atggtataat agttctatga attatgaagc aagtaaacaa ctaaccgatg
    13321 cacgatttaa gcgtcttgtt ggtgttcaac gcacgacttt tgaagagatg ttagctgtat
    13381 taaaaacagc ttatcaactt aaacacgcaa aaggtggacg aaaacctaaa ttaagcctag
    13441 aagaccttct tatggccact cttcaatatg tgcgagaata tcgaacttat gaagaaattg
    13501 cggctgatct tggtattcac gaaagcaact tactccgtcg gagccaatgg gttgaagtaa
    13561 ctcttgttca aaggtggtgt tgcgatttca agaactcctc tcagttctga ggacacggta
    13621 atgattgatg cgacggaagt aaaaatcaat cgacctaaaa aaagaattag cgaattattc
    13681 tggtaaaaag aaatttcacg ctatgaagac tcaagcgatt gtcacaagtc aagggagaat
    13741 t
//
LOCUS       DAVBBO010000058        12576 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ST1
            SAMEA2066453-rid20184263.denovo.058, whole genome shotgun sequence.
ACCESSION   DAVBBO010000058 DAVBBO010000000
VERSION     DAVBBO010000058.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2066453
            Sequence Read Archive: ERR351777
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 12576)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12576)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980402.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980402.1
            Genome Coverage       :: 176x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:17:33
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,141
            CDSs (total)                      :: 2,104
            Genes (coding)                    :: 1,953
            CDSs (with protein)               :: 1,953
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 16S)
            partial rRNAs                     :: 1 (23S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 151
            CDSs (without protein)            :: 151
            Pseudo Genes (ambiguous residues) :: 0 of 151
            Pseudo Genes (frameshifted)       :: 73 of 151
            Pseudo Genes (incomplete)         :: 76 of 151
            Pseudo Genes (internal stop)      :: 40 of 151
            Pseudo Genes (multiple problems)  :: 32 of 151
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12576
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2066453-rid20184263.denovo.058"
                     /strain="ST1"
                     /db_xref="taxon:1313"
     gene            <1..126
                     /locus_tag="VQU30_001783"
     CDS             <1..126
                     /locus_tag="VQU30_001783"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS5/IS1182 family transposase"
                     /protein_id="HET2447842.1"
                     /translation="ENIFAKVKTFKMFSTTYRNHRKRFGLRMNLIAGIINHELGF"
     gene            318..2609
                     /gene="pcrA"
                     /locus_tag="VQU30_001784"
     CDS             318..2609
                     /gene="pcrA"
                     /locus_tag="VQU30_001784"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000992850.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA helicase PcrA"
                     /protein_id="HET2447843.1"
                     /translation="MNALLNGMNDRQAEAVQTTEGPLLIMAGAGSGKTRVLTHRIAYL
                     IDEKLVNPWNILAITFTNKAAREMKERAYSLNPATQDCLIATFHSMCVRILRRDADHI
                     GYNRNFTIVDPGEQRTLMKRILKQLNLDPKKWNERTILGTISNAKNDLIDDVAYAAQA
                     GDMYTQIVAQCYTTYQKELRQSESVDFDDLIMLTLRLFDQNPDVLTYYQQKFQYIHVD
                     EYQDTNHAQYQLVKLLASRFKNICVVGDADQSIYGWRGADMQNILDFEKDYPKAKVVL
                     LEENYRSTKTILQAANEVIKNNKNRRPKNLWTQNADGEQIVYYRADDELDEAVFVART
                     IDELSRSQNFLHKDFAVLYRTNAQSRTIEEALLKSNIPYTMVGGTKFYSRKEIRDIIA
                     YLNLIANLSDNISFERIINEPKRGIGLGTVEKIRDFANLQNMSMLDASANIMLSGIKG
                     KAAQSIWDFANMMLDLREQLDHLSITELVESVLEKTGYVDILNAQATLESKARVENIE
                     EFLSVTKNFDDTTDVTEEETGLDKLSRFLNDLALIADTDSGSQETSEVTLMTLHAAKG
                     LEFPVVFLIGMEENVFPLSRATEDPDELEEERRLAYVGITRAEKILYLTNANSRLLFG
                     RTNYNRPTRFINEISSDLLEYQGLARPANTSFKASYSSGSISFGQGMSLAQALQDRKR
                     GAAPKSIQSSGLPFGQFTAGAKSASSEANWSIGDIALHKKWGEGTVLEVSGSGARQEL
                     KINFPEVGLKKLLASVAPIEKKI"
     gene            2652..3332
                     /gene="radC"
                     /locus_tag="VQU30_001785"
     CDS             2652..3332
                     /gene="radC"
                     /locus_tag="VQU30_001785"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000286923.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RadC"
                     /protein_id="HET2447844.1"
                     /translation="MYSISFQEDSLLPRERLAKEGVEALSNQELLAILLRTGTRQASV
                     FEIAQKVLNNLSSLTDLKKMTLQELQSLSGIGRVKAIELQAMIELGHRIHKHETLEME
                     SILSSQKLAKKMQQELGDKKQEHLVALYLNTQNQIIHQQTIFIGSVTRSIAEPREILH
                     YAIKHMATSLILVHNHPSGAVAPSQNDDHVTKLVKEACELMGIVLLDHLIVSHSNYFS
                     YREKTDLI"
     gene            complement(3329..4018)
                     /locus_tag="VQU30_001786"
     CDS             complement(3329..4018)
                     /locus_tag="VQU30_001786"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gamma-glutamyl-gamma-aminobutyrate hydrolase
                     family protein"
                     /protein_id="HET2447845.1"
                     /translation="MKKPVIGITGNEKAHPDDDIMMSYAAKGFVEGVKDAGGIPIILP
                     IGDQEMACHYISLIDKLILTGGQNVDPKFYGEPKTIDSDDYNLQRDIFELALIKEAIK
                     QKKPIFSVCRGTQLFNVAMGGTLYQDIEDHWQDSSVEYTTQRLVTEPDTVLQEIYGEI
                     SHINSFHHQSIKDLAPNLKVVAHDPKDGIIEAVMSTDDVAFLGVQWHPELLFENRPKD
                     KKLFDYVVNEL"
     gene            complement(4036..4677)
                     /locus_tag="VQU30_001787"
     CDS             complement(4036..4677)
                     /locus_tag="VQU30_001787"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000653420.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="redox-sensing transcriptional repressor Rex"
                     /protein_id="HET2447846.1"
                     /translation="MKDKQFAIPKATAKRLSLYYRIFKRFHAEKIERANSKQIAEAIG
                     IDSATVRRDFSYFSELGRRGFGYDVKKLMTFFADLLNDNSITNVMLVGIGNMGHALLH
                     YRFHERNKMKIIMAFDLDDHPEVGTQTPDGIPIYGISQIKDKIKDADVKTAILTVPSV
                     KSQEVANLLVDAGVKGILSFSPVHLHLPKDVVVQYVDLTSELQTLLYFMRKED"
     gene            complement(4760..4975)
                     /locus_tag="VQU30_001788"
     CDS             complement(4760..4975)
                     /locus_tag="VQU30_001788"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000462494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4649 family protein"
                     /protein_id="HET2447847.1"
                     /translation="MFELTYKDCYHVERTLKYEDHEALMLTLSGCVTLPDTLYVTSLT
                     FRGQKVYQGLVGDLYRFLSHADFLHQN"
     gene            complement(4983..5330)
                     /locus_tag="VQU30_001789"
     CDS             complement(4983..5330)
                     /locus_tag="VQU30_001789"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000863538.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1831 domain-containing protein"
                     /protein_id="HET2447848.1"
                     /translation="MAFEKIIQLKNCRYDYTLSPSVKKFTLKDNTFFETKVGNYELTR
                     LLEKVPNSGEGFQLKIIINKELTGAKINITDKFSLRLVDIFKSEDHHIHQEKFYFLMD
                     SLVERGVFTKSER"
     gene            complement(5335..6450)
                     /locus_tag="VQU30_001790"
     CDS             complement(5335..6450)
                     /locus_tag="VQU30_001790"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000639661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase"
                     /protein_id="HET2447849.1"
                     /translation="MIYLDNAATTPMSAVAISAMTKVMQETHGNPSSIHGHGRQAGKL
                     LREARQELAQLLRTKPQHIFFTSGGTEGNNTTIIGYCLRHQEQGKHIITTAIEHHAVL
                     ETIDYLVQHFGFEATIIQPENQEITAQQIQKALRDDTILVSTMFANNETGNLLPIAEI
                     GQILKQHPAAYHVDAVQAIGKIPIHSEELGIDFLTASAHKFHGPKGIGFLYASSMDFD
                     SYLHGGDQEQKKRAGTENLPAIVGMVAALKEDLEKQEEHFQHVQNLETAFLAELEGIQ
                     YYLNRGKHHLPYVLNIGFPGQKNDLLLLRLDLAGISISTGSACTAGVVQSSHVLEAMY
                     GANSERLKESLRISLSPQNTVEDLQTLAKTLKEIIGG"
     gene            complement(6460..7419)
                     /locus_tag="VQU30_001791"
     CDS             complement(6460..7419)
                     /locus_tag="VQU30_001791"
                     /EC_number="2.7.6.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001280885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribose-phosphate diphosphokinase"
                     /protein_id="HET2447850.1"
                     /translation="MSDRKNMKLFALNSNQEIAQKIAQAVGVPLGKLSSRQFSDGEIQ
                     VNIEESVRGYDVYIIQSTSFPVNNHLMELLIMVDACVRASAHSINVVLPYFGYARQDR
                     IACPREPLTAKLVANMLVKAGVDRILTLDLHAVQVQGFFDIPVDNLFTVPLFAKHYCD
                     KGLLGSDVVVVSPKNSGVKRARSLAEYLDAPIAIIDYPQDDATRNEGYIIGDVEGKKA
                     ILIDDILNTGRTFSEASKIVEREGATEIYAVSSHGLFVEGAAELLDNTNIKEILVTDS
                     VATKEKTPKNVCYITASELIGDAIVRIHERKPVSPLFAYNKKK"
     gene            complement(7532..8101)
                     /locus_tag="VQU30_001792"
     CDS             complement(7532..8101)
                     /locus_tag="VQU30_001792"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000681289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CYTH domain-containing protein"
                     /protein_id="HET2447851.1"
                     /translation="MKHLEIELKTLLKKDEYNRLKDQFTGVTPVLQTNYYIDTPDFEL
                     REKKVAMRIRTFEDWAELTLKVPQSVGNMEYNQKLQLKDAEDYLSKEELPQGLVLDEL
                     AKHGIQSKNWQVLGCLTTLRYEMKTAIGLMALDQSRYFDITDYELELEVENHEQGKQD
                     FRQFLEKNQISYQKAPSKLVRFVKSMKNS"
     gene            8229..8900
                     /locus_tag="VQU30_001793"
     CDS             8229..8900
                     /locus_tag="VQU30_001793"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000171686.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP pyrophosphokinase family protein"
                     /protein_id="HET2447852.1"
                     /translation="MTLEWEEFLDPYIQAVGELKIKLRGIRKQYRKQNKHSPIEFVTG
                     RVKPIESIKEKMARRGITYATLEHDLQDIAGLRVMVQFVDDVKEVVDILHKRQDMRII
                     QERDYITHRKASGYRSYHVVVEYTVDTINGAKTILAEIQIRTLAMNFWATIEHSLNYK
                     YQGDFPDEIKKRLEITARIAHQLDEEMGEIRDDIQEAQALFDPLSRKLNDGVGNSDDT
                     DEEYR"
     gene            8884..9702
                     /locus_tag="VQU30_001794"
     CDS             8884..9702
                     /locus_tag="VQU30_001794"
                     /EC_number="2.7.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000799053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD kinase"
                     /protein_id="HET2447853.1"
                     /translation="MKNTGKRIDLIANRKPQSQRVLYELRDRLKRNQFILNDTNPDIV
                     ISIGGDGMLLSAFHKYENQLDKVRFIGLHTGHLGFYTDYRDFELDKLVTNLQLDTGAR
                     VSYPVLNVKVFLENGEVKIFRALNEASIRRSDRTMVADIVINGVPFERFRGDGLTVST
                     PTGSTAYNKSLGGAVLHPTIEALQLTEIASLNNRVYRTLGSSIIVPKKDKIELIPTRN
                     DYHTISVDNSVYSFRNIERIEYQIDHHKIHFVATPSHTSFWNRVKDAFIGEVDE"
     gene            9699..10595
                     /locus_tag="VQU30_001795"
     CDS             9699..10595
                     /locus_tag="VQU30_001795"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001209987.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RluA family pseudouridine synthase"
                     /protein_id="HET2447854.1"
                     /translation="MRFEFIADEHVKVKTFLKKHEVSKGLLAKIKFRGGAILVNNQPQ
                     NATYLLDVGDYVTIDIPAEEGFETLEAIEHPLDILYEDDHFLVLNKPYGVASIPSVNH
                     SNTIANFIKGYYVKQNYENQQVHIVTRLDRDTSGLMLFAKHGYAHARLDKQLQKKSIE
                     KRYFALVKGDGHLEPEGEIIAPIARDEDSIITRRVAKGGKYAHTSYKIVASYGNIHLV
                     YIHLHTGRTHQIRVHFSHIGFPLLGDDLYGGSLEDGIQRQALHCHYLSFYHPFLEQDL
                     QLESPLPDDFSNLITQLSTNTL"
     gene            10639..11613
                     /gene="pta"
                     /locus_tag="VQU30_001796"
     CDS             10639..11613
                     /gene="pta"
                     /locus_tag="VQU30_001796"
                     /EC_number="2.3.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004252952.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate acetyltransferase"
                     /protein_id="HET2447855.1"
                     /translation="MEVFESLKANLVGKNARIVLPEGEEPRILQATKRLVKETEVIPV
                     LLGNPEKIKIYLEIEGIMDGYEVIDPQHYPQFEEMVSALVERRKGKMTEEDVRKVLVE
                     DVNYFGVMLVYLGLVDGMVSGAIHSTASTVRPALQIIKTRPNVTRTSGAFLMVRGTER
                     YLFGDCAININPDAEALAEIAINSAITAKMFGIEPKIAMLSYSTKGSGFGESVDKVVE
                     ATKIAHDLRPDLEIDGELQFDAAFVPETAALKAPGSTVAGQANVFIFPGIEAGNIGYK
                     MAERLGGFAAVGPVLQGLNKPVNDLSRGCNADDVYKLTLITAAQAVHQ"
     gene            complement(11929..12576)
                     /locus_tag="VQU30_001797"
                     /pseudo
     CDS             complement(11929..12576)
                     /locus_tag="VQU30_001797"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000433508.1"
                     /note="frameshifted; incomplete; missing N-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=3
                     /transl_table=11
                     /product="transposase"
BASE COUNT         3662 a         2397 c         2703 g         3814 t
ORIGIN      
        1 gagaacatct ttgccaaagt aaaaacgttt aaaatgtttt caacaaccta tcgaaatcat
       61 cgtaaacgct tcggattacg aatgaatttg attgctggca ttatcaatca tgaactagga
      121 ttctagtttt gcaggaagtc tattgaggta ttgagctagt ttatgaaaaa attgggtgaa
      181 aaagtcgagt gttttagaaa cccacagtgt agtattctag tttcaatcca ctatattttg
      241 ctactccccg taaagtttct attttccctg atttctgata taatagaaat attgacttca
      301 agagtaagga agagaagatg aacgcattat taaatggaat gaatgaccgt caggctgagg
      361 cggtgcaaac gacagaaggt cccttgctaa tcatggcagg agctggttct ggaaagactc
      421 gtgttttaac ccaccgtatc gcttatttga ttgatgaaaa gctggtcaat ccttggaata
      481 tcttggccat tacctttacc aacaaggctg cgcgtgagat gaaagagcgt gcttatagcc
      541 tcaatccagc tactcaggac tgtctgattg cgaccttcca ctccatgtgt gtgcgtattt
      601 tgcgtcgcga tgcggaccat attggctaca atcgtaattt tacaattgtg gatcctggtg
      661 aacagcgaac gctcatgaaa cgtattctca aacagttgaa cttggatcct aaaaaatgga
      721 atgaacgaac tattttgggg accatttcca atgctaagaa tgatttgatt gatgatgttg
      781 cttatgctgc tcaagctggc gatatgtata cgcaaattgt ggcccagtgt tatacaacct
      841 atcaaaaaga acttcgtcag tctgaatccg ttgactttga tgatttgatt atgctgacct
      901 tgcgtctctt tgatcaaaat cctgatgttt tgacctacta ccagcaaaaa ttccaataca
      961 tccacgttga tgagtaccaa gataccaacc acgctcagta ccaattggtc aaactcttgg
     1021 cttcccgttt taaaaatatc tgtgtggttg gggatgcgga ccagtctatc tacggttggc
     1081 gtggtgctga tatgcagaat atcttggact ttgaaaagga ttaccccaaa gctaaggttg
     1141 ttttgttgga ggaaaattac cgctcaacca aaaccattct ccaagcggcc aacgaggtta
     1201 ttaaaaataa taaaaatcgc cgtcctaaaa atctctggac tcaaaacgct gatggggagc
     1261 aaatcgttta ctatcgtgct gatgatgagc tggatgaggc tgtatttgta gccagaacca
     1321 tcgatgaact tagtcgcagt caaaacttcc ttcataagga ttttgcagtt ctctatcgga
     1381 ctaatgccca gtcccgtaca attgaggaag ccctgctcaa gtctaacatt ccttatacca
     1441 tggttggcgg aaccaaattc tacagccgta aggaaattcg cgatattatt gcttatctca
     1501 accttattgc taatttgagt gacaacatta gttttgagcg tattatcaac gagcctaaac
     1561 gtggaattgg tctaggtaca gttgagaaaa tccgtgattt tgcaaatttg caaaatatgt
     1621 ctatgctgga tgcttctgct aatattatgt tgtctggtat caagggtaag gcagcccaat
     1681 ctatctggga ttttgccaat atgatgcttg atttgcggga gcagctagac cacttaagca
     1741 ttacagagtt ggttgagtcc gtcctagaaa aaacaggtta tgtcgatatt cttaacgccc
     1801 aagcgactct agaaagcaag gcaagggttg aaaatatcga agagtttctt tctgttacga
     1861 agaactttga tgacaccact gatgtgacag aagaggaaac tggtctggac aaactgagtc
     1921 gtttcttaaa tgacttggct ttgattgccg acacagattc aggtagtcag gagacatcag
     1981 aagtgacctt gatgaccctg catgctgcca aaggtctcga atttccagtt gtctttttga
     2041 ttgggatgga agaaaatgtc tttccactta gtcgtgcgac tgaagatcca gatgaattag
     2101 aagaagagcg ccgtctagcc tatgtaggta tcacgcgtgc agagaaaatt ctctatctga
     2161 ccaatgccaa ctcacgcttg ctttttggtc gtaccaatta taaccgtccg actcgtttta
     2221 ttaacgaaat cagttcagac ttgcttgagt atcaaggtct ggctcgtcct gcaaatacaa
     2281 gctttaaggc atcatatagc agtggtagta tttcctttgg tcaaggtatg agtttggctc
     2341 aggctcttca agaccgtaaa cgcggtgctg ccccaaaatc gatccagtca agcggtcttc
     2401 catttggtca atttacagct ggcgcaaaat cagcatctag cgaggcaaat tggtccattg
     2461 gtgacattgc tctccacaag aaatggggag agggaactgt tctggaagtt tcaggtagcg
     2521 gtgctaggca ggaattgaaa atcaatttcc cagaagtagg tttgaaaaaa cttttagcca
     2581 gtgtggctcc aattgagaaa aaaatctaat tttccatcct tctcacgaat aataaagtga
     2641 ggaggatttt tatgtacagt atttcattcc aagaagattc actattacca agagaaaggc
     2701 tggccaagga aggagttgaa gcgcttagta accaagagtt gctagctatt ttactcagga
     2761 caggaacacg tcaagctagc gtttttgaaa ttgcccaaaa agtcttgaac aatctttcaa
     2821 gcctaacgga tttgaaaaaa atgaccctgc aggaattgca gagtttgtct ggtattgggc
     2881 gtgttaaggc catagaatta caagctatga ttgaactggg gcatcgtatt cacaaacacg
     2941 agactcttga aatggaaagt attctcagca gtcaaaagtt ggccaagaag atgcagcagg
     3001 aattagggga taaaaaacaa gagcacctgg tggcactcta tctcaatact caaaatcaaa
     3061 tcatccatca gcagaccatt tttatcggtt ctgtaactcg tagtatcgct gaaccgcgag
     3121 agattcttca ctatgcaatc aagcatatgg cgacttctct tatcttggtc cacaatcatc
     3181 cttcaggagc ggtagcgcct agccaaaatg atgatcatgt cactaaactt gttaaagaag
     3241 cctgcgaatt gatggggatt gttctcttgg accatttgat tgtctctcat tctaattact
     3301 ttagttatcg tgaaaagaca gatttaatct aaagttcatt aacgacatag tcaaagagtt
     3361 ttttatcttt gggacgattt tcaaaaagaa gttctggatg ccattggaca ccgagaaagg
     3421 cgacatcatc cgtactcatg acagcctcaa tgataccatc tttaggatca tgagccacaa
     3481 cttttaaatt tggtgctaag tccttgatgc tctggtggtg gaaggagttg atatgagaga
     3541 tttctccata gatttcttgg agaacggtat ctggttctgt taccaagcgt tgagttgtgt
     3601 actcaacaga agaatcctgc caatggtctt cgatatcttg gtacaaagtt ccacccatgg
     3661 caacgttaaa gagttgggta ccacggcaga cagagaaaat gggctttttc tgtttaatag
     3721 cttccttgat gagggccagt tcgaagatat ctctttgaag gttatagtca tcgctatcaa
     3781 tggttttggg ttcgccataa aattttggat cgacattttg cccacctgtc aagatgagct
     3841 tgtcaatcaa actgatatag tggcaggcca tttcttgatc accaatcggt aggatgatgg
     3901 gaatccctcc agcatcttta acgccttcaa caaagccttt tgctgcgtag ctcatcatga
     3961 tgtcatcatc tggatgagct ttttcgtttc ctgtaatccc aataactggt tttttcataa
     4021 aatgattttc gctttctaat cctcttttcg catgaagtag aggagggttt ggagttcact
     4081 tgtcaaatcg acatactgaa cgaccacgtc ttttggtaaa tgcagatgga ctggtgaaaa
     4141 actgagaatt cctttcacac cagcatcaac caagagatta gcaacctctt gtgacttgac
     4201 gctgggaaca gttaggatag cagtcttcac atcagcatcc ttgattttat ccttgatctg
     4261 agaaatcccg taaatgggaa tcccgtcagg agtttgggta ccgacttcag gatggtcgtc
     4321 taggtcaaag gccatgataa tcttcatctt gttacgttcg tggaagcggt agtggagaag
     4381 ggcatggccc atatttccaa taccaaccag catgacattg gtaatagagt tgtcattgag
     4441 caaatcggca aaaaatgtca ttagtttttt gacatcatag ccaaaaccac gacgaccaag
     4501 ttcactaaaa taggaaaaat cacgacgtac ggtcgctgaa tcaataccga tagcctctgc
     4561 aatttgctta gagttggcac gttcaatctt ttctgcatga aatctcttaa aaattcgata
     4621 gtagagagag agtctttttg ctgtagcttt tggaatagca aactgtttat ctttcacaaa
     4681 atcacaacct ttctattctt ctattttata gaaacattgt gaaaaaatca acaaaaataa
     4741 gaaaaaacta agaaaaatct tagttttgat gtaaaaaatc tgcatgagat agaaaacggt
     4801 agaggtctcc gaccagaccc tgataaactt tttggcccct aaaagtcaga gaagtcacat
     4861 aaagtgtatc tggtaaggtt acacatcctg acaaagtcaa catgagagcc tcatgatcct
     4921 catacttgag agtacgctct acatgatagc agtccttata ggtcagttca aacattttgg
     4981 ctctatcttt ccgattttgt aaagacacca cgttctacca agctatccat gaggaagtag
     5041 aatttttcct gatgaatatg gtggtcttct gatttgaaaa tatcaactag acgaaggcta
     5101 aacttgtcag tgatattgat tttagcccct gtaagttcct tgttaatgat gattttgagt
     5161 tggaagcctt caccgctgtt tggcactttt tccaaaaggc gagtcagttc atagttacca
     5221 accttagttt caaaaaaggt gttatctttg agggtgaatt ttttaacaga agggctaaga
     5281 gtgtaatcgt aacgacaatt ttttaactga atgatttttt caaatgccat atggctaacc
     5341 tccgataatt tcttttaagg tttttgcgag ggtttgtagg tcttcaacgg tattttgtgg
     5401 cgacaaactg atgcgaaggg attccttcaa gcgttctgaa tttgcgccat acatggcttc
     5461 aagaacatgg ctggattgga caacgcctgc agtacaggct gagccagtag agattgaaat
     5521 tccagctaaa tctagccgaa ggagtaagag gtcatttttc tgaccaggaa atccaatatt
     5581 gagaacataa gggagatgat gttttcctct attcaagtaa tactgaatgc cctccagctc
     5641 tgccagaaag gcggtttcta gattttgtac atgttgaaaa tgttcttctt gtttttctag
     5701 gtcttctttt agggctgcaa ccatgcctac gatagcaggc agattttcag ttcctgcacg
     5761 ttttttctgt tcctggtctc cgccatgtag ataggaatca aagtccatgc tagatgcgta
     5821 gagaaaaccg attcccttag gaccatggaa tttgtgggca gaagcagtga gaaaatcaat
     5881 gcccaattct tctgaatgaa ttgggatttt accaatagcc tgaactgcat caacatgata
     5941 ggcagcaggg tgttgcttga gtatttggcc aatttcagcg atgggcagta ggtttcctgt
     6001 ctcattattg gcaaacatgg tagaaaccaa aatcgtatcg tcacgtaaag ccttttgaat
     6061 ttgctgggct gtgatttctt gattttctgg ctggataatg gttgcttcaa acccaaagtg
     6121 ttgaaccaag taatcaattg tttcaaggac agcatggtgc tcgatggcag ttgtgatgat
     6181 atgttttcct tgttcttggt gacgaagaca gtagccaatg atggtagtat tattgccttc
     6241 agtcccacca gaagtgaaaa agatatgttg aggttttgtc cttagtaact gggctagttc
     6301 ctgacgggct tctcgcaaga gtttgccagc ttgacgacca tgaccatgaa tactagaagg
     6361 atttccgtgg gtttcttgca taaccttggt catagctgaa atagcaactg ctgacatagg
     6421 agtcgttgca gcattgtcca aataaatcaa agaatcacct tatttctttt tattgtaggc
     6481 aaagagtggg ctgactggtt ttctttcgtg aatacggacg atagcatcac caattaactc
     6541 actagcagtg atgtagcata catttttagg agttttttct tttgttgcta ctgaatcagt
     6601 cacaagaatt tctttaatat tagtattgtc aagaagctca gcagctccct cgacgaagag
     6661 accgtggcta gaaacagcat aaatttctgt agctccttca cgttcaacga ttttagaagc
     6721 ttcagagaag gtacgtcctg tatttaaaat atcatcaatc aagatagctt tcttaccttc
     6781 aacatcacca ataatataac cttcgttacg agttgcatcg tcttgagggt agtcgataat
     6841 ggcgatagga gcatcaagat attcagccag gctacgcgca cgtttgacac ctgaattttt
     6901 agggctaacg acaacaacat ctgaaccaag caatccttta tcgcagtaat gttttgcgaa
     6961 taggggaaca gtgaaaagat tatccactgg aatatcaaag aaaccttgaa cctgaacggc
     7021 atgcaaatca agagtcagga tacgatcaac tccagcctta accagcatat tggcaactag
     7081 ttttgctgta agtggctcac gaggacaagc aatgcggtct tgacgtgcat agccaaaata
     7141 tggaaggaca acgttgatac tgtgggcact tgcacgcaca caagcatcga ccatgattaa
     7201 caattccatt aggtggttgt tgacagggaa acttgttgat tggatgatgt aaacatcata
     7261 accacggaca ctttcttcga tatttacttg gatttctccg tctgaaaatt gacgtgatga
     7321 tagttttcca agtgggacac caacagcttg ggcaattttt tgtgcaatct cttggttaga
     7381 gttgagtgcg aaaagtttca tgttttttct atctgacatt atagaccgtc ctctgtaaac
     7441 tttataaatc ctagttatat ttaccttaca tatatgaact gggatttgtg tatttttatc
     7501 ttttctattt taccaaaaaa tggagattat ttcagctatt tttcatactt ttgacaaatc
     7561 gaaccaattt tgaaggagct ttttggtagg aaatctgatt tttctctaaa aattgtcgga
     7621 aatcctgttt gccttgctca tgattttcca cttcaagctc caattcgtaa tctgttatat
     7681 caaagtatcg gctctgatcc agtgccatga gaccaatagc tgttttcatt tcatagcgaa
     7741 gcgttgttag acaaccaaga acctgccagt tcttactttg gataccatgt ttcgccaatt
     7801 catccagtac tagtccttga ggaagttctt ccttactcag atagtcctca gcatctttta
     7861 gttgcaattt ttggttgtat tccatgtttc caacactctg cgggactttg agtgtcaact
     7921 cagcccagtc ttcaaaggtt cgaatgcgca tagcgacttt cttttctcgc agttcaaaat
     7981 caggcgtgtc gatgtagtaa tttgtttgaa gaacaggagt gacacctgtg aactggtctt
     8041 ttagacgatt gtattcatct tttttcaata gtgttttcaa ttcaatttct aaatgtttca
     8101 tttttcttac ctttttttat cgttgaaagc ggatttatgg tataataagc attgtattta
     8161 ttgtatatga atctggagaa aaaatcaaag atatttttga cggataatat gagaacaagg
     8221 gagaatatat gaccttagaa tgggaagaat ttctagatcc ttacattcaa gctgttggtg
     8281 agttaaagat taaacttcgt ggtattcgta agcaatatcg taagcaaaat aagcattctc
     8341 caattgagtt tgtgaccggt cgagtcaagc caattgagag catcaaagaa aaaatggctc
     8401 gtcgtggcat tacttatgcg accttggaac acgatttgca ggatattgct ggcttacgtg
     8461 tgatggttca gtttgtagat gacgtcaagg aagtagtgga tattttgcac aagcgtcagg
     8521 atatgcgaat catacaggag cgagattaca ttactcatag aaaagcatca ggctatcgtt
     8581 cctatcatgt ggtagtagaa tatacggttg ataccatcaa tggagctaag actattttgg
     8641 cagaaattca aattcgtact ttggccatga atttctgggc aacgatagaa cattctctca
     8701 actacaagta ccaaggggat ttcccagatg agattaagaa gcgactggaa attacagcta
     8761 gaatcgccca tcagttggat gaagaaatgg gtgaaattcg tgatgatatc caagaagccc
     8821 aggcactttt tgatcctttg agtagaaaat taaatgacgg tgtaggaaac agtgacgata
     8881 cagatgaaga atacaggtaa acgaattgat ctgatagcca atagaaaacc gcagagtcaa
     8941 agggttttgt atgaattgcg agatcgtttg aagagaaatc agtttatact caatgatacc
     9001 aatccggata ttgtcatttc cattggcggg gatggtatgc tcttgtcggc ctttcataag
     9061 tacgaaaatc agcttgacaa ggtccgcttt atcggtcttc atactggaca tttgggcttc
     9121 tatacagatt atcgtgattt tgagttggac aagctagtga ctaatttgca gctagatact
     9181 ggggcaaggg tttcttaccc tgttctgaat gtgaaggtct ttcttgaaaa tggtgaagtt
     9241 aagattttca gagcactcaa cgaagccagc atccgcaggt ctgatcgaac tatggtggca
     9301 gatattgtaa taaatggtgt tccctttgaa cgttttcgtg gagacgggct aacagtttcg
     9361 acaccgactg gtagtactgc ctataacaag tctcttggcg gtgctgtttt acaccctacc
     9421 attgaagctt tgcaattaac ggaaattgcc agccttaata atcgtgttta tcgaacactg
     9481 ggctcttcca ttattgtgcc taagaaggat aagattgaac ttattccaac aagaaacgat
     9541 tatcatacta tttcggttga caatagcgtt tattctttcc gtaatattga gcgtattgag
     9601 tatcaaatcg accatcataa gattcacttt gtcgcgactc ctagccatac cagtttctgg
     9661 aaccgtgtta aggatgcctt tatcggtgag gtggatgaat gaggtttgaa tttatcgcag
     9721 atgaacatgt caaggttaag acctttttaa aaaagcacga ggtttctaag ggattgctgg
     9781 ctaagattaa gtttcgaggt ggagctattc tggtcaataa tcaaccgcaa aatgcaacgt
     9841 atctattgga cgttggagac tacgttacca ttgacattcc cgctgaggaa ggctttgaaa
     9901 ccttggaggc tattgagcat ccattagata ttctctatga ggatgaccac tttctagtct
     9961 tgaataaacc ctatggagtg gcttctattc ctagtgtcaa tcactctaac accattgcca
    10021 attttatcaa gggttactat gtcaagcaaa attatgaaaa tcagcaggtt cacattgtta
    10081 ccagactaga tagggacact tctggcttga tgctctttgc caagcacggt tatgcccatg
    10141 cacgattaga caagcagttg cagaagaaat ctatcgagaa acgctacttt gctttggtta
    10201 agggagatgg acatttggag ccagaagggg aaattattgc tccgattgcg cgtgatgaag
    10261 attccattat taccagacga gtggctaaag gcggaaagta tgcccatact tcatacaaga
    10321 ttgtagcttc ttatggaaat attcacttgg tctatattca cctgcacact ggtcgaaccc
    10381 atcaaatccg agtccatttt tctcatatcg gttttccttt gctgggagat gatttgtatg
    10441 gtggtagtct ggaagatggt attcaacgtc aggctctgca ttgccattac ctatcctttt
    10501 atcatccatt tttagagcaa gacttgcagt tagaaagtcc cttgccggat gatttcagta
    10561 accttattac ccagttatca actaatactc tataaaaact gtctcagagt ataattatta
    10621 tcttaaagga gaaaactcat ggaagttttt gaaagtctca aagccaacct tgttggtaaa
    10681 aatgctcgta tcgttctccc tgaaggggaa gagcctcgta ttcttcaagc aacaaaacgc
    10741 ttagtaaaag aaacagaagt gattcctgtt ttgcttggaa atcctgaaaa aattaaaatt
    10801 tatcttgaaa ttgaaggaat catggatggt tatgaggtca tcgaccctca acattatcct
    10861 caatttgaag aaatggtttc tgccttggtg gagcgtcgca agggcaaaat gactgaagaa
    10921 gatgtacgca aggttttggt tgaagatgtc aactactttg gtgtgatgtt ggtttacttg
    10981 ggcttggttg atggaatggt gtcaggagcg attcactcaa cagcttcaac agttcgtcca
    11041 gctctacaaa tcatcaaaac tcgtccaaat gtaactcgta cttcaggagc cttcctcatg
    11101 gttcgtggta cggaacgtta cctatttgga gactgtgcca ttaacatcaa tccagatgca
    11161 gaagccttgg ctgaaattgc catcaactca gcaatcacag ctaagatgtt tggcatcgaa
    11221 cctaaaattg ccatgttgag ctattctact aaaggttcag ggtttggtga aagcgttgat
    11281 aaggtcgttg aagcaactaa aattgctcac gacttgcgtc ctgaccttga aatcgatggt
    11341 gagttgcaat ttgatgcagc ctttgttcct gaaactgcag ctctgaaagc tcctggaagt
    11401 acggtagctg gtcaagcaaa tgtcttcatc ttcccaggta tcgaggccgg aaatatcggt
    11461 tacaagatgg ctgaacgcct gggtggcttt gcggctgtag gacctgtttt gcaaggttta
    11521 aacaagccag ttaatgatct ttctcgtgga tgtaatgcag atgatgttta caagttgacc
    11581 ctcatcacag cagctcaagc agttcatcaa tagtgaaaac tataaagcga tatactatgc
    11641 tatactgtag ttatgaaact atgtacgaaa agcactgcca ttaattcctg agaactaaat
    11701 tactgattgg tgtcaaaaag gaaaacttcc aagcgatgat atcctgtcta tacacgacct
    11761 atagaaatct gtaatatgta tgtccgtaaa acgataattt ccctttttga ttttaaatga
    11821 gtatgaaaag agaatttttt catgagaaaa cgcataatat taagtgtctt gacacctgct
    11881 attatgcgtt ttctggctct ttgtcaactg tagtgggttg aagaaaagct aagctcgaga
    11941 aaggacaaat tttgtccttt cttttttgat attcagagcg gtaaaaatcc gttttttgaa
    12001 gttttcaaag ttccgaaaac caaaggcatt gcgcttgata agtttgatga gattattggt
    12061 cgcttccaat ttggcgtttg aatagggtag ttgaagggcg ttgacgattt tctctttgtc
    12121 ctttagaaag gttttaaaga cagtctgaaa aagaggatga acctgcttta gattgtcctc
    12181 aatgagtccg aaaaatttct ccggttcctt attctgaaag tgaaacagca agagttgata
    12241 gagctgatag tgatgtttca agtcttgtga atagctcaaa agcttgtcta aaatctcttt
    12301 attggttaaa tgcatacgaa aagtaggacg ataaaatcgc ttatcactca gtttacggct
    12361 atcctgttga atgagtttcc agtagcgctt gatagccttg tattcatggg atttcggatg
    12421 atggcttgtg ttctgctctc aagaacagtt atgatattga gcttatcaaa gtcctgagca
    12481 ataaagctca tctccatctc ccgattgaaa cagtcactcc ccggactgtt tcaacgtccc
    12541 aagacataat ctcaggaaga cgcgaaaaat catgct
//
LOCUS       DAVBBO010000059        12573 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ST1
            SAMEA2066453-rid20184263.denovo.059, whole genome shotgun sequence.
ACCESSION   DAVBBO010000059 DAVBBO010000000
VERSION     DAVBBO010000059.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2066453
            Sequence Read Archive: ERR351777
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 12573)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12573)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980402.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980402.1
            Genome Coverage       :: 176x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:17:33
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,141
            CDSs (total)                      :: 2,104
            Genes (coding)                    :: 1,953
            CDSs (with protein)               :: 1,953
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 16S)
            partial rRNAs                     :: 1 (23S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 151
            CDSs (without protein)            :: 151
            Pseudo Genes (ambiguous residues) :: 0 of 151
            Pseudo Genes (frameshifted)       :: 73 of 151
            Pseudo Genes (incomplete)         :: 76 of 151
            Pseudo Genes (internal stop)      :: 40 of 151
            Pseudo Genes (multiple problems)  :: 32 of 151
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12573
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2066453-rid20184263.denovo.059"
                     /strain="ST1"
                     /db_xref="taxon:1313"
     gene            complement(251..433)
                     /locus_tag="VQU30_001798"
     CDS             complement(251..433)
                     /locus_tag="VQU30_001798"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000268343.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2447856.1"
                     /translation="MAVIFKNVLIEEKTEEEKQHILSILNGEYDLSDDVSCRLRRLNE
                     ESKRLEVFVKETNSLV"
     gene            complement(649..1881)
                     /locus_tag="VQU30_001799"
     CDS             complement(649..1881)
                     /locus_tag="VQU30_001799"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002992300.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotide sugar dehydrogenase"
                     /protein_id="HET2447857.1"
                     /translation="MKIAVAGTGYVGLSIAILLAQHHQVVAVDIIPEKVELINKKKSP
                     IQDDYIEKYLAEKELNLVATLNAEEAYENADFIVIAAPTNYDPKKNFFDTSSVEAVIE
                     AVMKYNPDAIIIIKSTVPVGYTKSVRRKFLTDNIMFSPEFLRESKALYDNLYPSRIII
                     GTDKDDKDLVKSAEIFVKMLQEGAVKENIETLYMDFTEAEAVKLFANTYLALRVSYFN
                     ELDTYSEMKGLDTQAIIDGVCLDPRIGSHYNNPSFGYGGYCLPKDTKQLLANYSDVPQ
                     EMITAIVQSNRTRKDYIADRILDLAGSYVGNDFYKPDKEKEIVVGIYRLTMKSNSDNF
                     RQSSIQGIMKRLKAKGVTIIIYEPTLESGTTFYGSQVVNDFEIFKKSSQVIVANRFDE
                     TLEDVRGKVYTRDIFKRD"
     gene            complement(1910..2980)
                     /gene="gla"
                     /locus_tag="VQU30_001800"
     CDS             complement(1910..2980)
                     /gene="gla"
                     /locus_tag="VQU30_001800"
                     /EC_number="5.1.3.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001214397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucuronate 4-epimerase Gla"
                     /protein_id="HET2447858.1"
                     /translation="MRGKTILITGVAGFIGSNLVRKLLELEGTMTIIGLDNLNDYYDI
                     ALKDYRLLQLNKLIQDYPEKNWIFIKGDIADKMLINKIFKSYHPQIVVNLAAQAGVRY
                     SITNPDVYIESNIVGFHNVLEACRHSYEIYDGGVEHLVYASSSSVYGGNKKIPFATED
                     KVDNPISLYAATKKTNELQAYAYSKIYNIPSTGLRFFTVYGPAGRPDMAYFGFTDKLR
                     SGSDIEIYNHGNCKRDFTYIDDIVEGIVRVMQSAPKKLVGSDNLPLAPYKVYNIGNSK
                     PENLLDFVDVLQQELIKAGVLPENYDFDSHKKLVPMQPGDVPVTYADTSDLERDFGFK
                     PKTSLREGLRKFAEWYKDYYNV"
     gene            complement(3048..4217)
                     /locus_tag="VQU30_001801"
     CDS             complement(3048..4217)
                     /locus_tag="VQU30_001801"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001818726.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligosaccharide flippase family protein"
                     /protein_id="HET2447859.1"
                     /translation="MRLSKKYWFALTSKFLLILLTLLSSIIINRGLGVEKKGDYAYVM
                     NLVEIFYILGGVGLGQAYSTFKRNHSNEYQNKFVFLTFIQGLLFGIIGLIIVLADVPI
                     DYGGVIIVLSSLSIMRTNLTMIAVIENSIKRNKIVLGVSVVYSVMLVLLLLFHLVSIE
                     MVFLVYAINEFLRIILFLYYYNMFPVFEHISIKEFFTIYKFGFLSMILTLLITFNYSI
                     DIIMLKQMSSSYNVGIYSVAVTFSNMFLMVPDSFKEILFGDSAKRTFEKNKAINAIKV
                     SFLFMILLIIGFLSFGEFAITLLYGSSYIKAFPITLVIFLGSLSMIFFKILQPIYISQ
                     GKQSVAIKILSVSALINISLNWYLIPNYQITGAAIASAISYTVCGLFFIIDYLRN"
     gene            complement(4403..5707)
                     /locus_tag="VQU30_001802"
     CDS             complement(4403..5707)
                     /locus_tag="VQU30_001802"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000672721.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligosaccharide repeat unit polymerase"
                     /protein_id="HET2447860.1"
                     /translation="MKFSLQSNDIKNKIILLVGVVFSGTLILCSENNDVTIPLFSMIF
                     LSFMAMIIVKFNIFHPYVWYSSFFTIYSISYPLLYRMEYINYGYTKDLIFMQWLALAT
                     LLLTLPSKAIVLSERKINLNNNNYLLFLNNMNTFITTVAIIYLLGSGFRNKGEIYSGA
                     NIVIMLVFSLVYFMILIHTYQLFIQLSTKKWRLLNCNTNTAIVICLFSIVTGERDYMF
                     TLFILDVIILFYFHKIKRFYLVMLVPLAALLIPLSAVFKYTLLSGQVSSINTNNIWFD
                     LLDGEFVSASRNLQILILHNMGNYFEGRSFFNDIVRIFYNTGYSNQTWFMDTFFPNVH
                     STKYGFTLVGEGYVNGGYFGIVMIFMLTGFLMRFLYINAQRNIYGMLIYLYMIPIFIY
                     STRADFANILSPLLKYAILGTLVIVFINRMVLISPLDEMGGE"
     gene            complement(5824..6978)
                     /locus_tag="VQU30_001803"
     CDS             complement(5824..6978)
                     /locus_tag="VQU30_001803"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000862350.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 4 protein"
                     /protein_id="HET2447861.1"
                     /translation="MKVFIATEFRCTIYKNEIYLKPKAYFIYERYAKAFGEIVLCSRY
                     EKVESYPEGYHKANFINKFIPIEGLHQVLFGQNKNKIIEGMIDSDLIVVRIPSIIGSK
                     TADYALKIGKPYLTEIMGDAWDSYWYHSLKGKLLAPYIYAKTKSIVKNANYCIYVTEK
                     YLQDRYPNIKSNIVASNVNITSVENRSLKSRLYKLKKFNPQKISIMTTASVNVRAKGH
                     RFVLEAMKRLEIQGILLDYYLAGDGDQSFLKKKAEELGVANRIHFLGELTTSQIYEYL
                     DKVDLYIQPSLQEGLPRAVIEAMSRACPCIGSNKAGIPELLGPHCLFTPSSSQAIAGS
                     IIDFISMDKEKMVIKQFEFSKKFLSSVLNKRRSDYFAQIRRELNNSDGLD"
     gene            complement(6975..7526)
                     /locus_tag="VQU30_001804"
     CDS             complement(6975..7526)
                     /locus_tag="VQU30_001804"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001079795.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyltransferase"
                     /protein_id="HET2447862.1"
                     /translation="MNRIIKNIVGLLRANICLILLKVCRNKDLTFHYFLKFGKNVTVE
                     QESNAKLILGKKIRVNAGGVLKVRKGAKLKISDDVFLSNNCMIACRKYIDIKSGVKCG
                     PGVLIYDHDYDVSVPGGLKAKKFKTAPVMIGENVWIGANSIVLKGVSIGENSVVAAGS
                     VVTKDIPADTIFIQKRLSREMKL"
     gene            complement(7519..8655)
                     /locus_tag="VQU30_001805"
     CDS             complement(7519..8655)
                     /locus_tag="VQU30_001805"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001053205.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 4 protein"
                     /protein_id="HET2447863.1"
                     /translation="MNLQKKKIMLITNHDDDIYCFRKEVIESLVEYGYEVLVSCPYGD
                     KIELMKSIQFEYEDITIDRRGINPLKDIRLFLSYIRLLRKYRPDVVLTYTVKPNVYAS
                     LAATILGIKYINNVTGLGSVLTMGSCVRSLVLLLFRISFRKSNCVFFQNEYNMKMLKT
                     LGLILGDSKLIPGSGVNIEKYPVQQYPNGGNGIQGETIVFNFIGRILKEKGIDTYLAA
                     AQIIKSRYPKTEFNIIGFIEPTESNYELKICDLEKKGIVYYLGQQKDVIPHITRSHAI
                     IHPSVYGEGMSNVLLENASSGRVLITTDNPGCKEIVKDRETGYIFQGGNVEELVSILE
                     VFLGLENEKRKEMGLQGRMYIEQYFSRQIIIDAYLDKIKGALDE"
     gene            complement(8796..9461)
                     /gene="cpsD"
                     /locus_tag="VQU30_001806"
     CDS             complement(8796..9461)
                     /gene="cpsD"
                     /locus_tag="VQU30_001806"
                     /EC_number="2.7.10.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001845065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide biosynthesis tyrosine autokinase
                     CpsD"
                     /protein_id="HET2447864.1"
                     /translation="MPTLEIAQKKLEFIKKAEEYYNTLCTNIQLSGDKLKVISVTSVN
                     PGEGKTTTSVNIAMSFARAGYKTLLFDGDIRNSVMSGFFKSREKITGLTEFLSGTADL
                     SHGLCDTNIENLFVVQSGSVSPNPTALLQSKNFNDMIETLRKYFDYIIVDTPPIGIVI
                     DAAIITQKCDASILITATGEANKRDVQKAKQQLEQTGELFLGVVLNKLDISVDKYGVY
                     GRK"
     gene            complement(9471..10163)
                     /gene="cpsC"
                     /locus_tag="VQU30_001807"
     CDS             complement(9471..10163)
                     /gene="cpsC"
                     /locus_tag="VQU30_001807"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000664160.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="capsular polysaccharide biosynthesis protein
                     CpsC"
                     /protein_id="HET2447865.1"
                     /translation="MKEQNTLEIDVLQLFRALWKRKLVILLVAIITSSVAFAYSTFVI
                     KPEFTSTTRIYLVNRNQGEKPGLTNQDLQAGAYLVKDYREIVLSQDVLEEVISDLKLD
                     LMPKGLANKIKVTVPVDTRIVSVSVSDRVPEEASRIANSLREVAAQKIISITRVSDVT
                     TLEEARPAISPSSPNIKRNTLIGFLAGVIGTSVIVLLLELLDTRVKRPEDIENALQMT
                     LLGVVPNLGKLK"
     gene            complement(10172..10903)
                     /locus_tag="VQU30_001808"
     CDS             complement(10172..10903)
                     /locus_tag="VQU30_001808"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000565352.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-protein phosphatase CpsB"
                     /protein_id="HET2447866.1"
                     /translation="MIDIHSHIVFDVDDGPKSREESKALLAESYRQGVRTIVSTSHRR
                     KGMFETPEEKIAENFLQVREIAKEVADDLVIAYGAEIYYTLDALEKLEKKEIPTLNDS
                     RYALIEFSMHTSYRQIHTGLSNILMLGITPVIAHIERYDALENNEKRVRELIDMGCYT
                     QINSYHVSKPKFFGEKYKFMKKRARYFLERDLVHVVASDMHNLDSRPPYMQQAYDIIA
                     KKYGAKKAKELFVDNPRKIIMDQLI"
     gene            complement(10905..12350)
                     /locus_tag="VQU30_001809"
     CDS             complement(10905..12350)
                     /locus_tag="VQU30_001809"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000091082.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LCP family protein"
                     /protein_id="HET2447867.1"
                     /translation="MSRRFKKSRSQKVKRSVNIVLLTIYLLLICFLLFLIFKYNILAF
                     RYLNLVVTALVLLVALVGLLLIIYKKAEKFTIFLLLFSILVSSVSLFAVQQFVGLTNR
                     LNATSNYSEYSISVAVLADSKIENVTQLTSVTAPTGTDNENIQKLLADIKSSQNTDLT
                     VNQSSSYLAAYKSLIAGETKAIVLNSVFENIIESEYPDYASKIKKIYTKGFTKKVEAP
                     KTSKNQSFNIYVSGIDTYGPISSVSRSDVNILMTVNRDTKKILLTTTPRDAYVPIADS
                     GNNQKDKLTHAGIYGVDSSIHTLENLYGVDINYYVRLNFTSFLKMIDLLGGVDVHNDQ
                     EFSALHGKFHFPVGNVHLDSEQALGFVRERYSLTDGDRDRGRNQQKVIVAIIQKLTST
                     EVLKNYSSILQGLQDSLQTNIPIETMIDLVNTQLESGGNYKVNSQDLKGTGRMDLPSY
                     AMPDSNLYVMEIDDSSLTVVKAAIQDVMEGR"
BASE COUNT         4237 a         2433 c         1656 g         4247 t
ORIGIN      
        1 aattcactta cttcatatta catttagcat gaaatgaaat aagcgaattc tactttgttt
       61 gcatacaatt aaaaatcaat tcctaaggat gttttaaata actgtgtaaa aggcataatt
      121 tcaccatttc ttagtttttc aatgctaaat tacatagtaa ctggagagct attagaaatc
      181 tctaacttcc tcatagttaa aaaatgacaa tgagatactt attgatttca attcattaac
      241 agaatacgaa ctagacaagt gagttcgtct ccttaacaaa cacttccaag cgtttacttt
      301 cctcattcag tcgtcgtaat ctacaactta catcatcaga taagtcatac tcaccattta
      361 gaatagatag aatatgttgt ttttcttctt cagtcttctc ttcaataagc acatttttaa
      421 aaattactgc cattatcagc acctcacttc gaaggaatat atgcaactat atcctattaa
      481 gtcaatctct actgacaaaa gaagtatatt tacttcacta agtgcgagcg agaatataga
      541 aatatcttta ttgttttaga tgagttgtcg ctatcctcca gctagttttt aactattcta
      601 tcattcaaat gatatagatt attagggact agaaatatac aaattgattt aatctctctt
      661 aaaaatatcc ctagtataaa ctttacccct cacatcttct aaagtctcat caaaacgatt
      721 tgcaacaatc acttgactag atttcttaaa tatttcaaaa tcattaacta cttgactacc
      781 atagaaagta gtaccacttt caagagttgg ttcgtaaata ataatagtaa caccttttgc
      841 tttcaaacgc ttcataatac cttgaataga agattgtcta aaattatctg aattactttt
      901 cattgttaaa cgataaattc ctacaacaat ctctttttct ttatctggtt tatagaaatc
      961 attgcctaca taagatccag caagatctaa aatacgatct gcaatataat cttttcttgt
     1021 ccgattactt tgtactatag ctgttatcat ttcttgtgga acgtcagaat aatttgcaag
     1081 aagttgcttg gtatctttag gaagacagta acccccataa ccaaaagaag gattattgta
     1141 gtgagaacct attctcggat ctaaacaaac tccatcaata atcgcttgag tatctagtcc
     1201 tttcatctca gaataagtat ctaactcgtt aaaataggaa acccggaggg caagataggt
     1261 attagcaaaa agttttactg cttcagcttc tgtaaaatcc atatacaatg tttcaatatt
     1321 ttctttcact gcaccttcct gaagcatttt tacaaaaatt tcagcagact ttaccaaatc
     1381 tttatcatct ttatctgtac ctataataat tcgactcgga tataggttat catataacgc
     1441 ttttgactcc cgtaaaaact caggactaaa cataatattg tctgtaagaa atttcctccg
     1501 tactgacttt gtatatccaa caggaacagt acttttaatt attataattg catcaggatt
     1561 atatttcata actgcttcaa tgacagcctc gactgaagat gtatcgaaaa aatttttttt
     1621 cggatcataa ttagttggag ccgcaataac tataaaatcc gcattctcat atgcttcctc
     1681 tgcattcaat gtagctacga gattcaattc tttttccgcg agatattttt ctatataatc
     1741 gtcttggata ggggacttct ttttattgat taactcaact ttctcaggaa tgatatctac
     1801 ggcaacaact tgatgatgtt gagccagtaa gattgcaata gataatccaa catatcctgt
     1861 acctgctact gctattttca taattttttc ctttctcaaa acactctcgt tatacattat
     1921 agtagtcttt ataccactct gcaaactttc tcaaaccttc tcgtaaagaa gtttttggtt
     1981 taaaaccaaa atctctctct aaatcacttg tatctgcata agtaacagga acatcgcctg
     2041 gttgcatagg aactaatttt ttatgactat caaaatcata attttccggc aaaactcctg
     2101 ccttgattag ctcctgttga agaacatcca caaaatctaa caaattttcg ggtttactat
     2161 tcccaatatt gtacacttta tatggggcta acggtaaatt atcagatccc actagtttct
     2221 tcggagctga ttgcatgacc cttactatcc cctcaacgat atcatctata taagtaaaat
     2281 ctcgtttaca attaccatga ttataaatct caatatcgga accacttcgc aatttatctg
     2341 taaatccaaa ataggccata tctgggcgcc cagcaggacc ataaactgta aaaaagcgta
     2401 agcctgtcga aggaatattg taaatctttg aataagcata cgcttgaagt tcatttgttt
     2461 ttttagtcgc agcatatagt gaaataggat tgtctacctt atcttctgtt gcaaacggga
     2521 tttttttatt tccaccatat accgatgagg acgatgcata aactaagtgt tccacaccac
     2581 catcatatat ctcatacgaa tgacgacaag cttccaacac attatgaaag ccaacgatat
     2641 tactttctat atatacatct ggatttgtaa tggagtagcg tactcctgcc tgggcagcta
     2701 gattaacaac aatctgagga tgataactct taaaaatctt attaataagc attttatctg
     2761 caatatcacc cttgataaat atccagtttt tttctggata atcctgaatt agcttattaa
     2821 gttgaagcaa tcgataatct ttaagtgcaa tatcatagta atcattcaaa ttgtccaaac
     2881 caatgattgt catcgttcct tctaattcca ataatttcct aaccagattt gatccaataa
     2941 aaccagctac tcctgtaatt agaattgttt ttcctctcat atcataatac ctcttgttat
     3001 ttttatattt tcgtccacta atacacattc tttaacaact attataatca atttctaaga
     3061 taatctataa taaaaaacaa accacataca gtataagaga ttgctgatgc tatcgcagct
     3121 cctgtaattt ggtagttagg aattaagtac cagtttaaac ttatatttat caaagccgac
     3181 acagataaaa tttttatagc tacactctgt ttaccctgag atatataaat tggttgtaaa
     3241 attttaaaga aaatcatcga taagcttcct aaaaaaatga ctaatgttat aggaaatgcc
     3301 tttatataac tggaaccata aaggagcgta atcgcaaatt ctccaaaaga aagaaatcca
     3361 ataattaata aaatcataaa tagaaatgat acttttattg catttattgc tttatttttc
     3421 tcaaaagttc ttttagccga atcaccaaat aaaatctctt taaatgagtc tggaaccatc
     3481 aaaaacatat tagaaaacgt aactgcgaca ctgtatatac ctacattata actactagac
     3541 atttgcttca acattatgat atcaatacta taattaaatg taattaatag agtaagaatc
     3601 atagaaagaa atccaaactt atatatagtg aaaaattctt taatactaat atgttcaaaa
     3661 actgggaaca tattgtaata gtataaaaat aaaatgatac gtaaaaattc attaatagca
     3721 tataccaaaa ataccatctc tatagaaact aaatgaaata gtaacaacaa tactagcata
     3781 acggaatata ctacgcttac tcctaataca atcttattcc tctttatact attttctatt
     3841 actgcaatca tagtaagatt tgttctcata atagatagac tggacaaaac tattattacc
     3901 ccaccataat ctatcggaac atcagctaaa actattatta aacctattat tccaaacaat
     3961 aatccttgaa taaaagttaa aaaaacaaat ttattctgat actcattaga atgattcctt
     4021 ttaaaggtcg agtaagcctg acctaaacca actccaccta aaatataaaa aatttctact
     4081 aagttcatta cataggcata atctcctttt ttttcaacac ctaatcccct attaattata
     4141 attgaggata aaagtgttaa taagattaac aaaaatttac tcgttaaagc aaaccaatat
     4201 ttcttagata gtctcactta ttttctccgt atgttaaatt ttataacagt aaatttaaaa
     4261 ttatagtata ttgaaataga atatgaacaa aacgattagg gaatttaaag taatttataa
     4321 aaattcttta gaagctgcat tgtactactc caacttcaaa ccactatagt atcaaaaagt
     4381 ataccccacc tttttaaata aactactcac cacccatttc atccaatggt gatatcaaca
     4441 ccattctatt gataaaaaca ataaccaatg ttcccaatat agcatattta agtaatggag
     4501 ataatatgtt agcaaaatca gcacgagtag aataaataaa aataggtatc atatacagat
     4561 atatcagcat cccgtatata tttctttgag cgtttatata aagaaatctc atcaaaaagc
     4621 ctgttagcat aaaaatcatt acaattccaa agtatcctcc attcacatat ccctctccca
     4681 caagagtaaa accatatttg gttgaatgta cgtttggaaa aaaggtgtcc ataaaccaag
     4741 tttgattaga ataccccgta ttataaaaaa ttcttactat gtcattaaaa aaagaacgac
     4801 cttcgaaata attgcccata ttatgtaata tcagaatctg taaattacga ctagctgata
     4861 caaactcacc atctagcaaa tcaaaccaaa tattatttgt atttatagat gaaacttgcc
     4921 cacttaataa agtatattta aaaactgcag ataacggaat cagtagtgcc gcaagcggaa
     4981 ctaacattac aagataaaaa cgttttattt tgtgaaagta aaataatata atcacatcaa
     5041 ggatgaataa agtaaacata taatctcttt cccctgtaac gatagagaag agacagataa
     5101 ctatcgctgt gttagtatta caatttagta gtctccattt tttagtactc aactgtataa
     5161 atagctgata tgtatgaatg agaatcataa aataaaccaa agaaaatact aacattatca
     5221 caatattggc acctgaatat atttcccctt tatttctaaa accacttcct aatagatata
     5281 taattgctac tgttgtgata aacgtattca tattattgag aaataataaa tagttattgt
     5341 tatttaggtt tattttcctt tcgcttaaca caatggcttt agaaggtaga gttaacaaca
     5401 aagttgccaa agccagccat tgcatgaaaa tcaaatcttt tgtataacca tagtttatat
     5461 actccattct atagagtagc gggtaagaaa tagaataaat agtaaagaag ctactatacc
     5521 acacataggg atgaaaaata ttaaatttca caattatcat tgccataaaa cttaaaaaaa
     5581 tcattgaaaa taatggaatt gtaacatcat tattttcact gcataaaatt aaagtccctg
     5641 aaaaaactac acctactaga agtattattt tattttttat atcatttgat tgtagactaa
     5701 acttcattta cttttttcct ttaactaata atttaaacgt aatgcgtatt caaaaatttg
     5761 attggctatg tagtcagttt ttatagcata tttaatatat cgaaacggat tttccatcgc
     5821 attttaatct aaaccatcag aattatttaa ttctcttcta atttgagcaa aatagtcact
     5881 tctgcgttta tttaatacac tcgaaagaaa tttttttgag aattcaaact gttttatcac
     5941 catcttttcc ttatccatac taataaaatc tataatagat cccgcaatcg cttgtgaaga
     6001 ggatggagta aatagacaat gtggccccag caactctgga attcctgctt tattagaccc
     6061 tatacaaggg caagcacggc tcatagcttc aattaccgca cgaggtaacc cttcttgtaa
     6121 acttggttgt atatataaat caactttatc caaatactca taaatttgtg atgtagtcaa
     6181 ttcccctaaa aaatggattc tattcgctac tcccaattcc tctgctttct tttttaagaa
     6241 actttgatca ccatcacctg ctaaataata atccaacaaa ataccttgta tttctaatct
     6301 cttcattgct tccaatacaa atctatggcc cttggctcgt acattcacag atgctgttgt
     6361 cattattgaa attttttgag gattaaattt tttcaactta taaagacggc tcttcaaaga
     6421 tctattctct acagaggtaa tattaacatt tgaagcaacg atattagatt taatattagg
     6481 atatctatct tgtaaatatt tttctgtcac gtatatgcaa taattagcgt tttttacaat
     6541 tgatttagtt ttggcgtata tatatggagc taataatttt ccctttaaac tatgatacca
     6601 gtaagaatcc caagcatccc ccattatttc tgtcagatac ggcttaccta tcttcaatgc
     6661 gtagtctgca gtttttgatc caattataga cggaatacga acaactatta agtcgctatc
     6721 aatcattcct tcaataatct tatttttatt ttgaccaaat agaacctgat gtagaccttc
     6781 tatagggata aatttattaa taaagttcgc tttatgatat ccttcagggt atgattccac
     6841 cttctcataa cgactacata gtacaatctc tccaaatgct ttagcatagc gctcataaat
     6901 aaaataagct ttcggtttta aatatatttc atttttatag attgtacatc taaattcagt
     6961 cgctataaat actttcataa tttcatctcc cttgataaac gtttctgaat aaatatagta
     7021 tcagctggaa tatcctttgt tacaacactt cctgctgcaa ccacactatt ctcaccaata
     7081 ctcactccct tcaagacaat gctgttagct ccaatccaaa cattttctcc aatcataact
     7141 ggggccgtct taaatttttt tgctttcaat ccacctggaa cactaacatc atagtcatga
     7201 tcatatataa gtactccagg accacatttt actccagatt taatatctat gtatttacga
     7261 caagctatca tacaattatt actcaaaaat acatcatcag aaatcttgag ttttgctcct
     7321 tttctaactt tcaatactcc cccggcgttt actctaatct tttttcctaa gattaattta
     7381 gcattagatt cctgttcgac agttacattc tttccaaatt ttaaaaaata atgaaaagta
     7441 agatccttgt ttcgacacac ttttaataat atcaagcaaa tatttgcacg aagtaaacca
     7501 acaatatttt ttataatcct attcatctaa agctcctttt attttatcta aataagcatc
     7561 tataataatt tgacgagaaa aatattgctc tatatacatt ctcccttgaa gtcccatctc
     7621 ttttcgtttt tcattttcta gacctaaaaa aacttccaat atagagacta gttcctcaac
     7681 atttccccct tgaaatatat agcctgtctc tctatcttta acaatttctt tgcaacctgg
     7741 attatctgtc gtaattaaaa cacgtcctga actagcgttt tctagtaata cattgctcat
     7801 tccttcacca tacacactgg gatggataat tgcatgggaa cgggtaatat gaggtatcac
     7861 atctttttgt tgtcccaaat aataaacgat tccttttttt tctaagtcac aaattttaag
     7921 ttcataatta ctctctgtcg gttctataaa gccaataata ttaaactctg ttttgggata
     7981 tcgactctta ataatttggg cagcagccag ataagtatct ataccttttt cttttaatat
     8041 cctaccaata aaattaaaaa cgattgtttc tccttgaatt ccatttccac catttggata
     8101 ctgttgcaca ggatactttt caatgttcac tcctgaccca ggtatcagct tagagtcacc
     8161 caaaatcaag ccaagagttt ttaacatttt catattatat tcattttgaa aaaaaacaca
     8221 atttgatttc ctaaaagaaa ttctaaacag taataacacc aggcttctta cacaagaacc
     8281 cattgttaag acactaccta aacctgttac gttatttata tattttattc ctaaaattgt
     8341 tgcagctagg ctagcatata catttggttt cacggtatat gtcaagacta catccggtct
     8401 atattttctc aataatctta tataactaag aaatagacga atatctttta aagggtttat
     8461 tcctcttcta tcaatagtaa tatcttcata ctcaaattga atagacttca tcaactctat
     8521 cttatctcca taaggacatg acactagcac ttcataccca tactcaacta gtgactctat
     8581 aacttctttt cgaaaacaat agatatcatc gtcatgatta gttattaaca taattttttt
     8641 cttttgtaaa ttcatcaaaa taatcttcct aaaatataat taaccgctac tccattatcc
     8701 tttacaacta tcattttaaa aatagtaatt ttctataagt aattgtttcc aaattgtgac
     8761 actttaaaat tctatacaca tatagaactt acaaactatt tacgaccgta aactccatac
     8821 ttatcaaccg agatatccaa tttatttaaa acaactccca ggaacagttc ccctgtttgt
     8881 tctaattgtt gtttcgcttt ttggacatca cgtttattcg cctcacctgt tgctgttatc
     8941 aagatggacg catcacactt ttgagtgata attgccgcat caataacaat tccaataggt
     9001 ggtgtatcaa caatgatata atcaaaatat ttacgcaatg tttcaatcat atcattaaaa
     9061 tttttacttt gtaacaaggc tgtagggttt ggtgatacag atcccgattg aactacaaat
     9121 aaattttcaa tatttgtatc acataaaccg tgagataaat cagctgtccc agataaaaat
     9181 tctgttagcc ctgtaatttt ttcacgagat ttaaaaaatc ctgacataac tgaatttcga
     9241 atatcgccat cgaacaaaag agttttatag cctgcacgcg caaatgacat tgctatattt
     9301 acggaagtag ttgtttttcc ttcccccgga ttaacagaag taacggaaat tacttttagt
     9361 ttatctccgc tcaactgtat atttgtacac aaggtattgt aatattcttc tgccttctta
     9421 atgaactcca gttttttttg tgctatttct aatgtcggca tctctctctc ctatttcaac
     9481 ttacccaagt ttggtacaac tcccaaaagt gtcatctgca gtgcattttc gatatcttcc
     9541 ggacgtttca cacgagtgtc caaaagttca agaagaagaa ctataacact agttccaatc
     9601 acccctgcca aaaaaccaat tagtgtattg cgtttaatat ttggcgaaga cggtgatatc
     9661 gccggtcttg cctcctccag tgttgtcaca tcagaaacac gagtaatact gataattttt
     9721 tgagcagcta cttctcttaa agagttagcg atacggcttg cctcttcagg aactcgatca
     9781 ctaactgaaa cagagacaat acgggtatca actggtactg ttactttaat tttattagcc
     9841 aaaccttttg gcatcaaatc tagtttcaaa tcagaaataa cttcctccaa aacatcctgc
     9901 gataggacaa tttcacgata gtctttaacc aagtatgctc ctgcctgcaa gtcttgattg
     9961 gttaaaccag gcttctctcc ctgattacgg ttaactagat aaatccgagt cgtactagta
    10021 aactcaggtt tgataacaaa agtactgtag gcaaaagcaa ctgaagaagt tataattgcc
    10081 actaataaaa tgaccaactt tcttttccat aaagctctga atagttgcaa tacatcgatt
    10141 tccaaagtgt tttgttcctt catattttct cctaaattaa ttgatccatt ataatttttc
    10201 tgggattatc tacaaaaagt tctttcgctt ttttcgctcc atatttctta gcaatgatat
    10261 catatgcctg ttgcatatat ggaggtctac tgtctaaatt gtgcatgtca cttgcaacta
    10321 catgaactaa atcacgttcc aaaaaatacc gagctctctt tttcatgaat ttatattttt
    10381 caccaaagaa cttaggtttt gaaacatgat aactatttat ctgagtatag caccccatat
    10441 caatcagttc acgaacacgt ttttcgttat tctctaaagc atcataacgt tcaatatgag
    10501 caattactgg cgtgattccc aacatcaaaa tattgctcaa tcccgtatga atctgacgat
    10561 aggaagtatg catgctaaac tcaatcaagg cataacgact atcattaagg gtaggaattt
    10621 cttttttttc tagcttttct agagcatcca gagtatagta tatctctgcg ccataagcaa
    10681 tgactaaatc atctgctact tcttttgcaa tttcccgaac ctgaagaaag ttttctgcta
    10741 tcttctcttc cggagtttca aacatgccct tgcgacggtg agaggtagag acaatggttc
    10801 tcaccccctg cctgtaggat tctgccaaga gagccttgct ttcctctctt gacttgggac
    10861 catcatctac atcaaagacg atgtgcgaat ggatgtctat cattttatct accctccatc
    10921 acatcctgta tagctgcttt aactacagtt aaactactat catctatttc catcacatag
    10981 aggttactgt ctggcattgc ataagaagga agatccatcc gacctgtccc ttttaaatct
    11041 tgagaattta ctttataatt ccctccactt tccaactgag tattcactaa atctatcata
    11101 gtctcaatcg gtatatttgt ttgaagagaa tcctgcaatc cttgaagaat actactatag
    11161 tttttcaaaa cctctgtaga agttaacttc tgaataattg ctacaatgac cttttgttgg
    11221 ttgcgaccac ggtcacggtc tccatcggtt agtgagtagc gttcacgtac aaaacctaaa
    11281 gcttgctcag agtctagatg gacattccct actgggaaat ggaacttccc atgtagagct
    11341 gaaaactctt gatcattatg aacatctacc cctcccaata agtcaatcat tttcaagaaa
    11401 gaagtgaagt tcaatcgcac atagtaattg atatccactc catagagatt ttctaaggtg
    11461 tgaatggacg aatcaactcc ataaatgccc gcatgggtta atttatcttt ttgattattt
    11521 ccactatctg cgattggtac ataggcatca cgtggcgttg tggtcaagag gattttcttg
    11581 gtatctcgat tgacagtcat taggatattg acatctgatc gcgacaccga actaatagga
    11641 ccataggtgt caattccact aacatagata ttgaaagact gattcttaga cgtcttagga
    11701 gcctctactt ttttagtgaa tcccttggta taaatctttt ttatcttcga tgcgtagtct
    11761 ggatactctg actcgatgat attttcaaag acactattta ggacaatggc cttagtctcc
    11821 cctgcaatca aactcttgta agctgccaag taagacgaac tctggttgac cgtcaaatcg
    11881 gtattctgac ttgacttgat atcagctagt agtttttgaa tattttcatt atcagtccca
    11941 gtcggtgctg tcacactcgt cagttgcgta acattttcga tcttactatc tgctaaaaca
    12001 gcgacactga ttgaatattc tgagtaatta gaagtcgcat ttaaacgatt ggtcagtcca
    12061 acaaactgct gtactgcaaa gagcgacact gagctgacaa ggatagagaa cagcaacaga
    12121 aaaatagtaa acttttcagc ttttttatag ataatcaaga gtagccctac caaggcaact
    12181 agtaggacta acgcagttac cactaggtta agatatctaa aagcaaggat attgtactta
    12241 aagattaaga acaataaaaa acaaattaac aataaataaa tagtcagcaa aacgatatta
    12301 acacttcgct tcactttctg tgaacgtgat tttttaaaac gtctactcat gattaacacc
    12361 tataccttga acatcataca attatatcac ttttttacgg taatgtctac acctttattt
    12421 tcactatctg catctttaag tatcttagta gacttcccgc gaaccaaaaa tatagtaaaa
    12481 tgaaataaga ataggacaaa tcaatcagga cagtcaaatc gatttctaac aatgttttag
    12541 aatcagatgt gtactattct agtttcaata taa
//
LOCUS       DAVBBO010000060        12562 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ST1
            SAMEA2066453-rid20184263.denovo.060, whole genome shotgun sequence.
ACCESSION   DAVBBO010000060 DAVBBO010000000
VERSION     DAVBBO010000060.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2066453
            Sequence Read Archive: ERR351777
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 12562)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12562)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980402.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980402.1
            Genome Coverage       :: 176x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:17:33
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,141
            CDSs (total)                      :: 2,104
            Genes (coding)                    :: 1,953
            CDSs (with protein)               :: 1,953
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 16S)
            partial rRNAs                     :: 1 (23S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 151
            CDSs (without protein)            :: 151
            Pseudo Genes (ambiguous residues) :: 0 of 151
            Pseudo Genes (frameshifted)       :: 73 of 151
            Pseudo Genes (incomplete)         :: 76 of 151
            Pseudo Genes (internal stop)      :: 40 of 151
            Pseudo Genes (multiple problems)  :: 32 of 151
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12562
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2066453-rid20184263.denovo.060"
                     /strain="ST1"
                     /db_xref="taxon:1313"
     gene            160..327
                     /locus_tag="VQU30_001810"
     CDS             160..327
                     /locus_tag="VQU30_001810"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000218559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET2447868.1"
                     /translation="MTVSGYLFQIFGLLDNENVSINLDLGLINRKCNYKEKDKLKKDV
                     LARVGLTHIHL"
     gene            343..603
                     /locus_tag="VQU30_001811"
     CDS             343..603
                     /locus_tag="VQU30_001811"
                     /inference="COORDINATES: protein motif:HMM:NF012235.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HET2447869.1"
                     /translation="MSGGETKRVALAKIILKNPPLIFADELTASLDSTTSQGIMKLLL
                     GMKNKNRLIIIATHNPDIWNQADEVINLNQLLQSIYIFYILK"
     gene            complement(707..1177)
                     /locus_tag="VQU30_001812"
     CDS             complement(707..1177)
                     /locus_tag="VQU30_001812"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001043003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine repressor"
                     /protein_id="HET2447870.1"
                     /translation="MNKSEHRHQLIRALITKNKIHTQAELQTLLAENDIQVTQATLSR
                     DIKNMNLSKVREEDSAYYVLNNGSISKWEKRLELYMEDALVWMRPVQHQVLLKTLPGL
                     AQSFGSIIDTLSFPDAIATLCGNDVCLIICEDADTAQKCFEELKKFAPPFFFEE"
     gene            complement(1194..3467)
                     /locus_tag="VQU30_001813"
     CDS             complement(1194..3467)
                     /locus_tag="VQU30_001813"
                     /EC_number="3.4.14.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Xaa-Pro dipeptidyl-peptidase"
                     /protein_id="HET2447871.1"
                     /translation="MRFNQYSYINFPKENVLSELKKCGFDLQNTANHKDSLETFLRRF
                     FFTYQDTNYPLSILAADKKTDLLTFFQSEDELTADIFYTVAFQLLGFSYLVDFEDSDV
                     FRKETGFPIIYGDLIENLYQLLNTRTKKGNTLIDQLVSDGLIPEDNDYHYFNGKSLAT
                     FSNQDVIREVVYVESRVDTDQKGLSDLVKVSIIRPRFDGKIPAIMTASPYHQGTNDKA
                     SDKALYKMEGELEVKLPHKIELEKPQLNLVQPQGKAELIAEAEEKLTHINSSYTLNDY
                     FLPRGFANLYVSGVGTKDSTGFMTNGDYQQIEAYKNVIDWLNGRCRAFTDHTRQRQVK
                     ADWSNGKVATTGLSYLGTMSNGLATTGVDGLEVIIAEAGISSWYNYYRENGLVTSPGG
                     YPGEDFDSLAELTYSRNLLASDYIRGNEAHQADLEKVKAQLDRKTGDYNQFWHDRNYL
                     LNAHKVKAEVVFTHGSQDWNVKPLHVYQMFHALPTHIHKHLFFHNGAHVYMNNWQSID
                     FRESINALLTKKLLGQETDFQLPTVIWQDNTAPQTWLSLDNFGGQENCETFSLGQEEQ
                     AIQNQYPDKDFERYGKTYQTFNTELYQGKANQITINLPVTKDLHLNGRAQLNLRIKSS
                     TNKGLLSAQLLEFGQKKYLQPYPAILSARTIDNGRYHMLENLCELPFRPEAQRVVTKG
                     YLNLQNRNDLLLVEDITADEWMDVQFELQPTIYKLKEGDTLRLVLYTTDFEITIRDNT
                     DYHLTVDLAQSMLTLPC"
     gene            3814..6915
                     /locus_tag="VQU30_001814"
     CDS             3814..6915
                     /locus_tag="VQU30_001814"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000561528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit alpha"
                     /protein_id="HET2447872.1"
                     /translation="MIAQLDTKTVYSFMESVISIEKYVRAAKEYGYTHLAMMDIDNLY
                     GAFDFLEITKKYGIHPLLGLEMTVFVDDQGVNLRFLALSSVGYQQLMKLSTAKMQGEK
                     TWSVLSQYLEDIAVIVPYFDRVESLELGCDYYIGVYPETLASEFHHPILPLYRVNAFE
                     SRDREVLQVLTAIKENLPLREVPLRSRQDVFISASSLEKLFQERFPQALDNLEKLISG
                     ISYDLDTSLKLPRFNPARPAVEELRERAELGLVQKGLTSKEYQDRLDQELSVIHDMGF
                     DDYFLVVWDLLRFGRSNGYYMGMGRGSAVGSLVSYALDITGIDPVEKNLIFERFLNRE
                     RYTMPDIDIDIPDIYRPDFIRYVGNKYGSKHAAQIVTFSTFGAKQALRDVLKRFGVPE
                     YELSAITKKISFRDNLKSAYEGNLQFRQQINSKLEYQKAFEIACKIEGYPRQTSVHAA
                     GVVISDQDLTNYIPLKYGDEIPLTQYDAHGVEASGLLKMDFLGLRNLTFVQKMQELLA
                     ETEGIHLKIEEIDLEDKETLALFASGNTKGIFQFEQPGAIRLLKRVQPVCFEDVVATT
                     SLNRPGASDYINNFVARKHGQEEVTVLDPVLEDILAPTYGIMLYQEQVMQVAQRLAGF
                     SLGKADILRRAMGKKDASAMHEMRASFIQGSLEAGHTVEKAEQVFDVMEKFAGYGFNR
                     SHAYAYSALAFQLAYFKTHYPAIFYQVMLNSSNSDYLIDALEAGFEVASLSINTIPYH
                     DKIANKAIYLGLKSIKGVSNDLALWIIENRPYSNIEDFIAKLPENYLKLPLLEPLVKV
                     GLFDSFEKNRQKVFNNLANLFEFVKELGSLFGDAIYSWQESEDWTEQEKFYMEQELLG
                     IGVSKHPLQAIASKAIYPITPIGNLSENSYAIILVEVQKIKVIRTKKGENMAFLQADD
                     SKKKLDVTLFSDLYRQVGQEVREGAFYYIKGKVQSRDGRLQMIAQEIREAVAERFWIQ
                     VKNHESDQEISRILEQFKGPIPVIIRYEEEQKTIVSPHHFVAKSDELEAKLNEIVMKT
                     IYR"
     gene            6997..8004
                     /gene="pfkA"
                     /locus_tag="VQU30_001815"
     CDS             6997..8004
                     /gene="pfkA"
                     /locus_tag="VQU30_001815"
                     /EC_number="2.7.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000820836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phosphofructokinase"
                     /protein_id="HET2447873.1"
                     /translation="MKRIAVLTSGGDAPGMNAAIRAVVRQAISEGMEVFGIYDGYAGM
                     VAGEIHPLDAASVGDIISRGGTFLHSARYPEFAQLEGQLKGIEQLKKHGIEGVVVIGG
                     DGSYHGAMRLTEHGFPAIGLPGTIDNDIVGTDFTIGFDTAVTTAMDAIDKIRDTSSSH
                     RRTFVIEVMGRNAGDIALWAGIATGADEIIIPEAGFKMEDIVASIKAGYECGKKHNII
                     VLAEGVMSAAEFGQKLKEAGDTSDLRVTELGHIQRGGSPTARDRVLASRMGAHAVKLL
                     KEGIGGVAVGIRNEKMVENPILGTAEEGALFSLTAEGKIVVNNPHKADIELSSLNKSL
                     S"
     gene            8061..9566
                     /gene="pyk"
                     /locus_tag="VQU30_001816"
     CDS             8061..9566
                     /gene="pyk"
                     /locus_tag="VQU30_001816"
                     /EC_number="2.7.1.40"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008809276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate kinase"
                     /protein_id="HET2447874.1"
                     /translation="MNKRVKIVATLGPAVEIRGGKKFGEDGYWGEKLDVEASAKNIAK
                     LIEAGANTFRFNFSHGDHQEQGERMATVKLAEKIAGKKVGFLLDTKGPEIRTELFEGE
                     AKEYSYKTGEKIRVATKQGIKSTREVIALNVAGALDIYDDVEVGRQVLVDDGKLGLRV
                     VAKDDATREFEVEVENDGIIAKQKGVNIPNTKIPFPALAERDNDDIRFGLEQGINFIA
                     ISFVRTAKDVNEVRAICEETGNGHVQLFAKIENQQGIDNLDEIIEAADGIMIARGDMG
                     IEVPFEMVPVYQKMIIKKVNAAGKVVITATNMLETMTEKPRATRSEVSDVFNAVIDGT
                     DATMLSGESANGKYPLESVTTMATIDKNAQALLNEYGRLDSDSFERNSKTEVMASAVK
                     DATSSMDIKLVVTLTKTGHTARLISKYRPNADILALTFDELTERGLMLNWGVIPMLTD
                     APSSTDDMFEIAERKAVEAGLVESGDDIVIVAGVPVGEAVRTNTMRIRTVR"
     gene            complement(10298..10523)
                     /locus_tag="VQU30_001817"
                     /pseudo
     CDS             complement(10298..10523)
                     /locus_tag="VQU30_001817"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001838792.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
     gene            11371..12243
                     /locus_tag="VQU30_001818"
     CDS             11371..12243
                     /locus_tag="VQU30_001818"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000749590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4300 family protein"
                     /protein_id="HET2447875.1"
                     /translation="MKKSRKLATLGICSALFLGLAACQQQHATSEGTNQRQSSSAKVP
                     WKASYTNLNNQVSTEEVKSLLSAHLDPNSVDAFFNLVNDYNTIVGSTGLSGDFTSFTH
                     TEYDVEKISHLWNQKKGDFVGTNCRINSYCLLKNSVTIPKLEKNDQLLFLDNDAIDKG
                     KVFDSQDKEEFDILFSRVPTEATTDVKVHAEKMETFFSQFQFNEKARMLSVVLHDNLD
                     GEYLFVGHVGVLVPADDGFLFVEKLTFEEPYQAIKFASKEDCYKYLGTKYADYTGEGL
                     AKPFIMDNDKWVKL"
     gene            complement(12389..12562)
                     /locus_tag="VQU30_001819"
                     /pseudo
     CDS             complement(12389..12562)
                     /locus_tag="VQU30_001819"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase family protein"
BASE COUNT         3833 a         2183 c         2679 g         3867 t
ORIGIN      
        1 ttttgtgata aaatgtaatt gttccatatg aatctttcta atgagttgtt ttgtcgcttt
       61 tcattatagg tcatatggga ctttttttct acaataaaat aggctccata atatctatag
      121 tggatttacc cactacaaat attatagaac ccttttttat tgacagtatc aggatatctt
      181 tttcaaattt ttggtttgtt agataatgaa aatgtttcta tcaatctaga tttaggatta
      241 ataaatcgta aatgtaatta taaagaaaaa gataagttaa aaaaagatgt attagcaaga
      301 gttggtctaa ctcatattca tctataacaa aagatatatg aattgtctgg cggtgaaaca
      361 aaacgtgttg ctttagcgaa aatcattctt aaaaatccac cattaatatt cgcggatgag
      421 ttgactgcat cactcgattc gacgacttca caaggaatta tgaaattgtt attaggtatg
      481 aaaaataaaa atcgtctaat catcattgca actcataatc ccgatatttg gaatcaagca
      541 gatgaagtta taaatttaaa tcaattatta cagtcaatat atatcttcta tattttaaag
      601 taattttatc tgaatccgtt aagagactat tgtcccaggc tctttctgat gttaaagact
      661 ttctaccagg ttttttaaaa gcataattgt tagttgtagt catttattat tcttcaaaga
      721 aaaatggtgg ggcgaatttt ttcagttctt caaagcactt ttgagcagta tctgcatctt
      781 cacagatgat aagacagaca tcattaccac aaagggtagc gatagcgtca gggaagctca
      841 aagtatcaat gatagaacca aaggattgag ccagtccagg aagggttttt agtaggactt
      901 ggtgttgaac tgggcgcatc cagacaaggg cgtcttccat gtagagttcg agacgttttt
      961 cccattttga gatggaacca ttgttaagaa cataataagc gctatcttct tcgcggactt
     1021 ttgataggtt catatttttg atgtcgcgtg agagggttgc ctgagttact tgaatgtcgt
     1081 tctcagcaag aagggtttgc aactcagcct gtgtatgaat cttgtttttt gtgataagag
     1141 cgcgtataag ttggtggcgg tgttctgatt tattcataat aatgtaactc cttttagcaa
     1201 ggtaaggtaa gcatggactg agcgaggtcg acagtcaagt ggtagtctgt attgtcacgg
     1261 atggtgattt caaagtcagt agtatagagg actaaacgga gagtgtctcc ttcttttagc
     1321 ttgtaaatag ttggctgcag ttcaaattga acgtccatcc attcatctgc agtaatatcc
     1381 tctactaaca gtaaatcatt tctattttgt aaattaaggt aaccttttgt cacgactctt
     1441 tgtgcctctg gtctaaatgg caattcacag agattttcca acatgtgata gcgaccgttg
     1501 tcaatggttc tagcacttaa aatagctgga taaggttgta ggtatttctt ttgcccaaat
     1561 tctagcagtt gggcagataa gagccccttg tttgtactgg atttgatacg aagattgagc
     1621 tgagcgcgac cgtttaggtg gagatcttta gtcacaggaa ggttaatagt aatctgatta
     1681 gctttccctt gatagagctc tgtattgaag gtttggtatg tcttaccata gcgctcaaaa
     1741 tccttatctg ggtactggtt ttgaatagct tgctcttctt gaccaagtga gaaggtttca
     1801 cagttttctt gcccaccgaa gttatcaagt gataaccaag tctgtggagc tgtattgtcc
     1861 tgccagataa cagtaggaag ttgaaagtct gtttcctgtc ctagtaattt cttggtcaat
     1921 aaggcattta tggactcacg gaagtcaatt gattgccaat tgttcatgta aacatgggca
     1981 ccattatgga aaaagagatg cttgtgtata tgagtaggaa gagcatggaa catctggtaa
     2041 acatgaagtg gtttgacatt ccaatcctga gaaccatgag taaagacaac ctctgccttt
     2101 actttatggg cattgagcag ataattgcgg tcatgccaaa actgattgta gtccccagtt
     2161 tttcggtcta gttgagcttt cactttttct aagtcagctt ggtgagcttc attgccacgg
     2221 atatagtcgc tagccaagag attacgagaa taggttaact cagcaaggga gtcaaagtcc
     2281 tcacctggat aaccacctgg gctagtcacc agaccgtttt cacggtagta gttgtaccat
     2341 gatgaaattc ctgcctcggc aatgataact tctaaaccat cgactcctgt agtcgcaaga
     2401 ccattggaca tggtacctag ataggaaagt cccgttgtag caacttttcc gtttgaccaa
     2461 tcagccttga cttgacgctg gcgcgtgtga tcagtaaagg cacggcaacg gccgttaagc
     2521 caatcgatga catttttata agcctcgatt tgctggtagt ctccattagt catgaaacct
     2581 gtcgagtctt tggtaccaac acctgagaca tagagattgg caaagcctct cggaaggaag
     2641 tagtcgttta gtgtatagct agagttgatg tgagttagct tttcctcagc ctctgctata
     2701 agctcagctt taccttgggg ttggacgaga tttagttgag gtttctctag ctcaatcttg
     2761 tgaggaagtt taacctcaag ctcgccctcc atcttgtaga gagccttgtc actagccttg
     2821 tcattggttc cctgatgata agggctggct gtcatgatgg cagggatttt tccatcaaaa
     2881 cgagggcgaa taatgctaac ctttactagg tctgatagcc ctttttggtc agtatcgaca
     2941 cgagactcaa cgtaaacgac ttcacgaatg acatcctggt tagaaaaagt agccaaactc
     3001 ttgccgttaa agtagtggta gtcattatcc tccggaataa gaccatcact aacaagttgg
     3061 tcgataagag tatttccttt tttggtgcga gtattgagta actgatagag attttcaatc
     3121 aagtcaccat atataatggg aaatccagtt tctttacgaa aaacgtcact atcttcgaag
     3181 tcaaccaaat aagaaaagcc taaaagttga aaagcaacag tataaaaaat atctgctgtc
     3241 agttcatctt ctgattgaaa aaatgtcagc aggtctgttt ttttatcagc tgctaggata
     3301 gaaagtgggt agttggtgtc ttgataagtg aaaaagaaac gacgtaaaaa ggtttcaagt
     3361 gagtctttgt gattggctgt attttgtaaa tcaaagccac atttttttag ttcagataag
     3421 acattttctt ttggaaaatt gatataacta tattgattaa aacgcataga acctccatat
     3481 agaatgacag ttaaggttat tatatcaaaa aaaaagcaga aagggaattg ttaacttcaa
     3541 aaggaaataa tccaataaaa atgaataaag tactaaattc aatatagaga acagagtaac
     3601 aataagaata aatagatagg gtataaaagt tctaggagat ttatattata tgctttctgt
     3661 ttttatatac aatatagtat aaatataaaa atgatgacaa aaatacaaat gaatagaaaa
     3721 taaattagta agctgatgaa atttttctca agagaagcca tttataggtg aaaatggtat
     3781 aatatagtga gaaggataga ggagaagtgt aaattgatcg cacaactaga tacaaaaaca
     3841 gtctatagtt ttatggaaag cgtcatttcg atcgaaaagt atgtgagagc agctaaagaa
     3901 tacggctaca ctcatttggc tatgatggat attgacaatc tttatggcgc tttcgacttt
     3961 ctagagatta caaaaaaata cggcattcat cctttgctag ggcttgaaat gacagtgttt
     4021 gtagatgatc agggagtgaa tttgcgcttt ttagctctat ctagtgtggg ctatcagcag
     4081 ttgatgaagc tttcgacagc caagatgcag ggggagaaaa cttggtcagt cctgtcccag
     4141 tacctggagg atatcgcggt cattgtgcct tattttgata gagttgagtc gttagaacta
     4201 ggctgtgatt actatatagg ggtttatcca gaaacactag caagcgaatt tcatcatcct
     4261 atcttacctc tttatcgggt caacgctttt gaaagcaggg atagagaagt tcttcaagtt
     4321 ttaacagcga ttaaagaaaa tctaccgctc agagaagttc ccttgcgttc gagacaagat
     4381 gtctttatat cagcaagttc tttagagaaa ctattccaag agcgttttcc gcaagctttg
     4441 gacaatttag aaaagcttat ttcaggcatt tcttacgact tggatactag tctgaaactg
     4501 cctcgtttta atccagctag accagcagta gaggagttga gagagcgtgc tgaactgggg
     4561 cttgttcaga aggggttgac tagtaaagaa tatcaagata gactagacca agaattgtct
     4621 gttattcatg atatgggctt tgatgattat ttcttggttg tttgggattt gttgcgtttt
     4681 ggacgatcga atggctatta tatgggaatg ggaaggggtt ctgcagtagg cagtttggtt
     4741 tcttatgcct tagacatcac ggggattgac ccagtagaga aaaatctgat ttttgaacgc
     4801 tttcttaatc gtgaacgcta taccatgcct gatattgata ttgatatccc agatatttat
     4861 cgtccagatt ttatcagata tgttggtaat aaatatggta gtaaacatgc ggcacaaatc
     4921 gttacttttt caacctttgg agccaagcaa gctcttcgag atgtcttgaa acgctttggt
     4981 gtgccagagt atgaattatc tgcaattact aagaaaatca gttttcgtga caatcttaag
     5041 tcggcctatg agggcaatct ccagtttcgt cagcaaatca atagtaagtt agaataccaa
     5101 aaagcttttg agattgcttg caagatagag ggctatccaa ggcaaacctc tgtccatgcg
     5161 gctggtgttg taattagtga ccaagattta accaactaca ttcctctaaa gtatggtgat
     5221 gaaattccac tgactcagta tgatgctcat ggagttgagg ctagcggact tttgaagatg
     5281 gactttctgg gactacgaaa tttgaccttt gtccagaaga tgcaagagtt gcttgctgaa
     5341 acagaaggta ttcatctgaa aattgaagaa atcgatttag aagacaaaga aacattagct
     5401 ttatttgcct ctggtaatac aaaaggtatc tttcaatttg agcaaccagg tgccattcgt
     5461 ctgcttaagc gtgtgcaacc agtctgtttt gaagatgtcg tcgcgactac ttctctaaat
     5521 cgaccgggtg ctagtgacta tatcaataat tttgtggcaa gaaagcatgg gcaggaagaa
     5581 gtgactgttc tggatccagt actggaggat attttggctc caacctacgg cataatgctc
     5641 tatcaggagc aggttatgca ggttgcccag cgacttgccg gatttagtct tgggaaagcc
     5701 gatattttgc gtcgggctat ggggaaaaag gatgcctctg ccatgcatga gatgagggct
     5761 tcctttattc aaggttcatt agaagctggt catactgtgg aaaaagcaga gcaggtcttt
     5821 gatgttatgg agaagtttgc aggttatggt tttaacaggt cacacgccta tgcctactca
     5881 gccttggcct tccagttggc ttatttcaaa acgcattatc cagccatttt ttatcaggtc
     5941 atgttaaatt cttccaacag tgattactta atagatgcac ttgaagcagg ttttgaagta
     6001 gcctctctat ccatcaacac cattccctat cacgataaaa ttgccaacaa ggccatctat
     6061 ctaggtttga aatccattaa aggagtcagt aatgatttag ctctctggat tattgaaaat
     6121 agaccttatt ctaacattga agattttata gctaaattac ctgagaatta tctgaaactt
     6181 cctctgctag aacctttggt aaaagttggt cttttcgatt catttgaaaa aaatcgtcaa
     6241 aaagtattta ataacttagc taatctattt gaatttgtga aagagttggg aagtttgttt
     6301 ggagatgcta tttatagttg gcaggaatcg gaagattgga cggaacaaga aaaattttat
     6361 atggaacaag agcttttagg gataggtgtc agcaaacatc cactacaagc tattgcaagt
     6421 aaggctattt acccgattac cccaatcgga aatttgtcag aaaatagcta tgctattatc
     6481 ttggttgaag ttcagaaaat aaaagtgatt cgtaccaaaa agggtgaaaa tatggccttc
     6541 ttacaggcag atgatagtaa gaaaaaattg gatgttacac tcttctcaga tttatatcga
     6601 caggttggtc aggaagtaag agaaggagca ttctactata tcaaagggaa agtccaatca
     6661 cgtgacggtc gtctgcaaat gattgcacaa gaaataagag aagcagttgc tgaacgcttt
     6721 tggatacagg tgaaaaatca tgaatcggat caagaaattt cacgtatttt agaacaattt
     6781 aaaggcccaa tcccagtcat catccggtat gaagaggaac agaaaaccat cgtttctccc
     6841 catcattttg tagctaaatc tgatgaatta gaggcgaaat tgaatgaaat cgttatgaaa
     6901 acgatttatc gctaaaaata cggaaaatag aagaatttta aaatcaaatg tgatataatc
     6961 aagaagaatg ttaaaagaaa aaggagcata accaatatga aacgtattgc tgttttgact
     7021 agtggtggag acgcccctgg tatgaacgct gccatccgtg cagttgttcg tcaagcaatt
     7081 tcagaaggaa tggaagtgtt tggtatctat gacggatatg ctggtatggt tgccggtgaa
     7141 attcatcccc tagatgcagc ttcagtaggg gacatcattt ctcgtggtgg tactttcctt
     7201 cactcagctc gttacccaga gttcgctcaa cttgaagggc aacttaaagg gattgagcaa
     7261 ttgaaaaaac acggaattga aggtgtagtt gttatcggtg gtgacggatc ttaccacggc
     7321 gctatgcgtt tgactgaaca tggcttccca gctattggtc ttccaggtac aatcgataac
     7381 gatatcgttg gtactgactt tacaatcggt tttgacacag cggttactac tgccatggac
     7441 gctatcgata agattcgtga tacatcatca agtcaccgtc gtacttttgt aatcgaagtt
     7501 atgggacgta acgctggtga tatcgctctt tgggctggta ttgcaactgg tgctgatgaa
     7561 atcatcatcc ctgaagcagg cttcaagatg gaagatatcg tagcaagcat caaagctggt
     7621 tatgaatgtg gtaaaaaaca caatatcatc gtcttagctg aaggtgtgat gtcagcggct
     7681 gaatttggtc aaaaacttaa agaagctgga gatacaagcg accttcgtgt aacagaactt
     7741 ggacatattc aacgtggtgg ttctccaact gcgcgtgacc gtgttttggc gtcacgtatg
     7801 ggtgcacatg ctgttaaact tcttaaagaa ggtatcggtg gtgttgcggt tggtattcgt
     7861 aacgaaaaaa tggttgaaaa tccaattctt ggtactgcag aagaaggggc attgtttagc
     7921 cttactgcag aaggtaagat tgtggttaac aacccgcaca aagccgatat tgagctatct
     7981 agcttgaata agagcttgtc ataatttaca atttagttaa taagaccaaa aaggtcatat
     8041 ataaaggagt cacaaaaatc atgaacaaac gtgtaaagat cgttgcaact ttgggtcctg
     8101 cggtagaaat ccgtggtggt aaaaaattcg gtgaggacgg atactggggt gaaaaacttg
     8161 atgttgaagc ttcagctaaa aacattgcta aattgattga agctggtgct aacacattcc
     8221 gattcaactt ctcacacggc gaccaccaag aacaaggtga gcgtatggca actgttaaac
     8281 ttgcggaaaa aattgcaggt aaaaaagttg gtttccttct tgatacaaaa ggacctgaaa
     8341 tccgtacaga attgttcgaa ggtgaagcta aagaatattc atacaaaact ggtgaaaaaa
     8401 ttcgtgttgc aactaaacaa ggaatcaaat caactcgtga agtgattgcg ttgaacgttg
     8461 ctggtgctct tgatatctat gatgatgttg aagttggtcg tcaagttttg gttgacgatg
     8521 gtaaacttgg tcttcgtgtg gttgctaaag atgatgcaac tcgtgaattt gaagttgaag
     8581 ttgaaaacga tggtatcatc gctaaacaaa aaggtgtgaa catccctaac actaaaattc
     8641 ctttcccagc tcttgctgaa cgcgataacg acgatatccg tttcggtctt gaacaaggta
     8701 tcaacttcat cgcaatttca ttcgtacgta ctgcaaaaga tgtgaacgaa gttcgtgcaa
     8761 tctgtgaaga aactggaaac ggacatgttc aattattcgc taaaatcgaa aaccaacaag
     8821 gtatcgataa cttagacgaa atcatcgaag cagctgatgg tattatgatt gctcgtggtg
     8881 atatgggtat cgaagtaccg ttcgaaatgg ttccagttta tcaaaaaatg attatcaaga
     8941 aagtcaatgc tgcaggtaaa gttgttatca ctgcaacaaa catgcttgaa acaatgactg
     9001 aaaaaccacg tgcaactcgt tcagaagtat cagacgtatt caacgctgtt atcgacggaa
     9061 ctgacgctac aatgctgtca ggcgagtctg caaacggtaa atacccactc gagtcagtaa
     9121 ctacaatggc tacaatcgac aagaatgctc aagctcttct taatgaatac ggacgtcttg
     9181 attcagattc atttgagcgt aactctaaga cagaagtaat ggcttctgct gttaaagatg
     9241 ctactagctc aatggatatc aaattggtcg taactcttac taagacaggt catactgcac
     9301 gtttgatttc taaataccgt ccaaatgctg acatcttagc attgacattt gacgaattga
     9361 cagaacgtgg cttgatgttg aactggggtg ttatcccaat gttgacagat gctccatctt
     9421 caactgacga tatgttcgaa atcgctgaac gtaaagcggt agaagcaggt ctcgttgagt
     9481 caggcgatga tatcgttatc gttgctggtg tgccagtagg agaagctgtt cgcacaaaca
     9541 caatgcgtat ccgcacagta cgttaagaaa aatataaaaa cctatcatat ccagctttag
     9601 agcttgtgtg ataggctttt tgtatagagg gtaagaaata ggcaaaactt tcataatgga
     9661 ttgatactct tcgaaaatca aattcaaacc acgtcagcgt cgccttaccg tatatatgtt
     9721 actgacttcg tcagttctat ctacaacctc aaagcagtgc tttgagcaac ctgcggctag
     9781 cttcctagtt tgctctttga ttttcattga gtatgaaata agatatgcac aaattgatta
     9841 ggaaattcaa atgaatttct acaaatgttt tagcaatcgt aatgtacttg tctagattcg
     9901 atctgatata ttttcgattt aatgatatgg tatttaaaac ctccaaagta gcttgctcca
     9961 ttcttttact tacgtgagtg tagatgttat ttactgtttt agcgtttttg tgttccactc
    10021 taaccattat agcattcttc tcagctagtg tactaaggag tgtgtgcctg aaaatatggg
    10081 aactaagggg ctggtttatc ggtttctcta gtttagtatt tgccttttgc aaagtgatgt
    10141 taaatgcctt tctctaaatt tacatatcac tattgtttaa caaaatctaa tctactttag
    10201 gtcacttatt ctttttttga aatgtagaat gaactttttc aaagtttttc gaatctttta
    10261 aaatctgttt gttttatatc gccattctcc ccctttttta attctcccta tatagcctga
    10321 caactttccc gatggtacga atatggttgc tttcgtctag gtggatgtcg gggtatttgg
    10381 gattgagttt ttttaaggta gccttggcgg agtttcttga catagttagc gccgtctact
    10441 tggaagatgc cgatggtatt atagtcaatc tgtggggtat tcttgataaa taggtagtcg
    10501 ctgtttctta tctttggctc catggacttg ctgacgacat aagcgattgg gtcgtagtcg
    10561 tctgggataa tggaaactcc ataactaaat cgtcgtcctg catcgagcgg ctacctgcag
    10621 agataaacta cctaacacga gagtaagtag tctgtctgta gtcgtccagt ctgatgattt
    10681 ttacgatatt tcgtttttct gctcatacag ttgcctctcg gcataggtca gaactttacc
    10741 ttgtctgggt ggtgcccgtt ggtcgtagat agattggata tcgctaggag aatccttttg
    10801 aactggagga aagagggtat caatcaagct actgaatact ttagctaagt caaatatagt
    10861 atttttctta gtagacctaa cccttttttc ataatttcca atggtgtttt tacttatacc
    10921 aatcttagta cccaattctt attgagtcca accattacta gtctatattg ttttatagtt
    10981 gattgagttt ggaatagtac gctgtagctg ctaaaacatt tctaggaatt aatttgactt
    11041 tcctaataga gttgttcata tcttatttca atctactatg tttttcacct ctaacaatcg
    11101 caatctcttc tttatccatg aatgaaatcg ctttctattt ttgtaagtaa agcatcacac
    11161 gaaatccacg aaaatgaaaa cctttgttgt gttttcgtaa aaaatttgtt gacagagcac
    11221 gaaacgccta ctataattaa atcaagctta aggaaataac aaaaaaacaa atcggaggga
    11281 aagacgatga acacattaaa tgagaaagta atcaatatct gtaaagcagt agttaaagaa
    11341 actttaatcc aagacattta ggagaaagaa atgaagaaat caagaaaatt agccacatta
    11401 ggaatctgtt cagccttgtt tttaggcttg gctgcttgtc aacaacaaca tgctacttct
    11461 gaggggacga atcaaaggca aagcagttca gcgaaagttc catggaaagc ttcatacacc
    11521 aacctaaaca accaggtaag tacagaagag gtcaaatctc tcttatcagc tcacttggat
    11581 ccaaatagtg ttgatgcatt ttttaatctc gttaatgact ataataccat tgtcggctca
    11641 actggcttat caggagattt cacttccttt actcacaccg aatacgatgt tgagaaaatc
    11701 agtcatctct ggaatcaaaa gaagggcgat ttcgttggga ccaactgccg tatcaatagt
    11761 tattgtcttt tgaaaaattc agtcaccatt ccaaagcttg aaaagaatga ccaattgctt
    11821 ttcctagata acgatgcgat tgataaagga aaggtctttg attcacaaga taaggaagag
    11881 tttgatattc tattttcgag agttccaact gaggcaacta cagatgtcaa ggttcacgct
    11941 gaaaagatgg aaacattctt ctcacaattt caattcaatg aaaaagctcg aatgctgtct
    12001 gtagtcttgc acgacaatct ggatggcgag tatctgtttg taggccatgt tggggtctta
    12061 gtacctgctg atgacggttt cttatttgta gagaaattga ctttcgaaga gccctaccaa
    12121 gcgattaaat ttgctagtaa ggaagattgc tacaagtatt tgggcaccaa gtatgcggat
    12181 tatacaggcg agggactggc taagcctttt atcatggata atgataagtg ggttaaactt
    12241 taatagtgtt atgatatgac agtaatctta ggatttttat ttctattttt gatgacttgg
    12301 tgggttattt caatcgttaa tagccagaaa ccacgcaaaa atgaaacatt tattggctat
    12361 atccaaagat acgatattga tgggaatggc tatcaatcat taccgtgtcc tcagaactga
    12421 gaggagttct tgaaaccgta aaaccgcttt gaacaagagt tacttcaacc cattggctcc
    12481 gacggagtaa gttgctttcg tgaataccaa aatcagccgc aatttgttca taagttcgat
    12541 attctcgcac atattgaaga gt
//
LOCUS       DAVBBO010000061        12123 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ST1
            SAMEA2066453-rid20184263.denovo.061, whole genome shotgun sequence.
ACCESSION   DAVBBO010000061 DAVBBO010000000
VERSION     DAVBBO010000061.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2066453
            Sequence Read Archive: ERR351777
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 12123)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12123)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980402.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980402.1
            Genome Coverage       :: 176x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:17:33
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,141
            CDSs (total)                      :: 2,104
            Genes (coding)                    :: 1,953
            CDSs (with protein)               :: 1,953
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 16S)
            partial rRNAs                     :: 1 (23S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 151
            CDSs (without protein)            :: 151
            Pseudo Genes (ambiguous residues) :: 0 of 151
            Pseudo Genes (frameshifted)       :: 73 of 151
            Pseudo Genes (incomplete)         :: 76 of 151
            Pseudo Genes (internal stop)      :: 40 of 151
            Pseudo Genes (multiple problems)  :: 32 of 151
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12123
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2066453-rid20184263.denovo.061"
                     /strain="ST1"
                     /db_xref="taxon:1313"
     gene            1..512
                     /locus_tag="VQU30_001820"
                     /pseudo
     CDS             1..512
                     /locus_tag="VQU30_001820"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="frameshifted; incomplete; missing N-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=2
                     /transl_table=11
                     /product="transposase"
     gene            662..916
                     /gene="blpM"
                     /locus_tag="VQU30_001821"
     CDS             662..916
                     /gene="blpM"
                     /locus_tag="VQU30_001821"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000379879.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-peptide bacteriocin subunit BlpM"
                     /protein_id="HET2447876.1"
                     /translation="MDTKIMEQFHEMDITMLSSIEGGKNNWQTNVLEGGGAAFGGWGL
                     GTAICAASGVGAPFMGACGYIGAKFGVDLWAGVTGATGGF"
     gene            932..1135
                     /gene="blpN"
                     /locus_tag="VQU30_001822"
     CDS             932..1135
                     /gene="blpN"
                     /locus_tag="VQU30_001822"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001099492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-peptide bacteriocin subunit BlpN"
                     /protein_id="HET2447877.1"
                     /translation="MNTYCNINETMLSEVYGGNSGGAAVVAALGCAAGGVKYGRLLGP
                     WGAAIGGIGGAVVCGYLAYTATS"
     gene            1379..1528
                     /gene="blpO"
                     /locus_tag="VQU30_001823"
     CDS             1379..1528
                     /gene="blpO"
                     /locus_tag="VQU30_001823"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001818346.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin-like peptide BlpO"
                     /protein_id="HET2447878.1"
                     /translation="MDTKMMSQFAVMDNEMLACVEGGDIDWGRKISCAAGVAYGAIDG
                     CATTV"
     gene            1632..1751
                     /locus_tag="VQU30_001824"
     CDS             1632..1751
                     /locus_tag="VQU30_001824"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000346296.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin"
                     /protein_id="HET2447879.1"
                     /translation="MDFKSFIIGLVVGIFGPYMDDLIRKIFSKSSKKDTDSTL"
     gene            2537..2935
                     /locus_tag="VQU30_001825"
     CDS             2537..2935
                     /locus_tag="VQU30_001825"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000877383.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="immunity protein"
                     /protein_id="HET2447880.1"
                     /translation="MKYRLFFVIFLSSVLDILLGTFLQISIVSIGWLVLYSGLFEVGV
                     FLLANKGVAVKIKEVDIRNRFKFIFGKTLWFQILLLIFLIIKLYLGLDARLILFYGHI
                     FIVFNALMYLLSSSQVSLKKKQTVFLILQQ"
     gene            2973..3662
                     /locus_tag="VQU30_001826"
     CDS             2973..3662
                     /locus_tag="VQU30_001826"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000760553.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HET2447881.1"
                     /translation="MKKYQLLFKISAVFSYLFFVFGLSQLTLIVQNYWQFSSQIGNFV
                     WIQNILSLLFIGVMIVVLVKTGHGYLFRIPRKKWLWYSILTVLVVVFQISFNVQTAKH
                     VQSTAEGWAVLIGYSGTNFAELGIYIALFFLVPLMEELIYRGLLQHAFFKHSRFGLDL
                     LLPSILFALPHFSSLPSLLDIFVFATVGIIFAGLTRYTKSIYPSYAVHVINNIVATFP
                     FLLTFLHRVLG"
     gene            3704..3952
                     /locus_tag="VQU30_001827"
     CDS             3704..3952
                     /locus_tag="VQU30_001827"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399200.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2447882.1"
                     /translation="MYKHLFFLDSKTLDRLTPYILVLASDTIAFNVFVLTFVSAVVFN
                     FLNSMLALMAIFIGAGYVVGFWLLKWFVLERLELKDDA"
     gene            3982..4593
                     /locus_tag="VQU30_001828"
     CDS             3982..4593
                     /locus_tag="VQU30_001828"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000394041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HET2447883.1"
                     /translation="MEFFDKFHALCFGFLVLIIVITVPYTINHGGFFQNESALILVSL
                     LVTSLSVAYARKFEMISFGMLSKKQLLLFIAIFLLSVLETLVYIHFFAVSSGSGVQHL
                     AEVSRGISLSLILTTSVFGPIQEELIFRGLLQGAVFDNSWLGLVLTSSLFSFMHGPSN
                     VPSFIFYLLGGLLLGFAYKKSQNLWVSTLVHMFYNSWPLLYYL"
     gene            4754..5548
                     /locus_tag="VQU30_001829"
     CDS             4754..5548
                     /locus_tag="VQU30_001829"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000363010.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphotransferase family protein"
                     /protein_id="HET2447884.1"
                     /translation="MDLGDNELTLTPIPGKSGKAYMGSYPDGKRIFVKMNTSPILPGL
                     AREQIAPQLLWSRRLADGRDMCAQEWLTGKILTPYDMNRKQIVNILTRLHRSRPLMTQ
                     LSRLGYAMETPVDLLQSWQETAPDALRKNHFISEVMADLRQTIPGFREDHATIVHGDV
                     RHSNWIETDSGLIYLVDWDSVRLTDRMFDVAHMLCHYISEHQWKEWLTYYGYKYNQTV
                     LSKLYWYGQLSYLSQISKYYMNQDLENVNREIHGLRHFRDKYGKRR"
     gene            5545..6180
                     /gene="trmB"
                     /locus_tag="VQU30_001830"
     CDS             5545..6180
                     /gene="trmB"
                     /locus_tag="VQU30_001830"
                     /EC_number="2.1.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001266107.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (guanosine(46)-N7)-methyltransferase TrmB"
                     /protein_id="HET2447885.1"
                     /translation="MRVRNRKGATELLEANPQYVVLNPLEAKAKWRDLFGNDNPIHVE
                     VGSGKGAFVSGMAKQNPDINYIGIDIQKSVLSYALDKVLEVGVPNIKLLWVDGSDLTD
                     YFEDGEIDRLYLNFSDPWPKKRHEKRRLTYKTFLDTFKRILPENGEIHFKTDNRGLFE
                     YSLVSFSQYGMKLNGVWLDLHASDFEGNVMTEYEQKFSNKGQVIYRVEAEF"
     gene            6306..6785
                     /gene="rimP"
                     /locus_tag="VQU30_001831"
     CDS             6306..6785
                     /gene="rimP"
                     /locus_tag="VQU30_001831"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000338698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome maturation factor RimP"
                     /protein_id="HET2447886.1"
                     /translation="MDAIATIVELVREVVEPVIEAPFELVDIEYGKIGSDMILSIFVD
                     KPEGITLNDTADLTEIISPVLDTIKPDPFPEQYFLEITSPGLERPLKTKDAVAGAVGK
                     YIHVGLYQAIDKQKVFEGTLLAFEEDELTMEYMDKTRKKTVQIPYSLVSKARLAVKL"
     gene            6829..7965
                     /gene="nusA"
                     /locus_tag="VQU30_001832"
     CDS             6829..7965
                     /gene="nusA"
                     /locus_tag="VQU30_001832"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000032293.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription termination/antitermination
                     protein NusA"
                     /protein_id="HET2447887.1"
                     /translation="MSKEMLEAFRILEEDKGIKKEDIIDAVVESLRSAYRRRYGQSDS
                     VAIDFNEKTGDFTVYTVREVVDEVFDSRLEISLKDALAINSAYELGDKIKFEEAPAEF
                     GRVAAQSAKQTIMEKMRKQTRAITYNTYKEHEQEIMSGTVERFDNRFIYVNLGSIEAQ
                     LSKQDQIPGEVFASHDRIEVYVYKVEDNPRGVNVFVSRSHPEMIKRLMEQEIPEVYDG
                     TVEIMSVAREAGDRTKVAVRSHNPNVDAIGTIVGRGGANIKKITSKFHPARYDAKNDR
                     MVPIEENIDVIEWVADPAEFIYNAIAPAEVDQVIFDENDSKRALVVVPDNKLSLAIGR
                     RGQNVRLAAHLTGYRIDIKSASEFEAMEDAASVELEVENDTVEE"
     gene            7987..8280
                     /locus_tag="VQU30_001833"
     CDS             7987..8280
                     /locus_tag="VQU30_001833"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000857559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlxR family protein"
                     /protein_id="HET2447888.1"
                     /translation="MKTRKIPLRKSVVSNEVIDKRDLLRIVKNKEGQVFIDPTGKANG
                     RGAYIKLDNAEALEAKKKKVFNRSFSMEVEESFYDELIAYVDHKVKRRELGLE"
     gene            8273..8572
                     /locus_tag="VQU30_001834"
     CDS             8273..8572
                     /locus_tag="VQU30_001834"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399195.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlxQ-related RNA-binding protein"
                     /protein_id="HET2447889.1"
                     /translation="MNKQKISNLLGLAQRAGRIISGEELVVKAIQDGKAKLVFLAHDA
                     GPNLTKKIQDKSHYYQVEIVTVFSTLELSIAVGKSRKVLAVTDAGFTKKMRSLME"
     gene            8589..11381
                     /gene="infB"
                     /locus_tag="VQU30_001835"
     CDS             8589..11381
                     /gene="infB"
                     /locus_tag="VQU30_001835"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863140.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-2"
                     /protein_id="HET2447890.1"
                     /translation="MSKKRLYEIAKELGKESKEVVARAKELGLDVKSHSSSVEEAVAA
                     KIAASFKPAAAPKVEAKPAAPKVSAEKKAEKSEPAKPAVAKEEAKPAEPVAPKTEKVA
                     VKPQSRNFKAEREARAKEQAERRKQNKGNNRDQQQNGNRQKNDGRNGGKQGQSNRDNR
                     RFNDQAKKQQGQQKRRNERRQQEDKRSNQAAPRIDFKARAAALKAEQNAEYARSSEER
                     FKQYQAAKEALAQANKRKEPEEIFEEAAKLAEQAQQVQAVVEVVPEKKEPAVDTRRKK
                     QARPDKNRDDYDHEEDGPRKQQKNRSSQNQVRNQKNSNWNNNKKNKKGNNKNNRNQTP
                     KPVTERKFHELPTEFEYTDGMTVAEIAKRIKREPAEIVKKLFMMGVMATQNQSLDGET
                     IELLMVDYGIEAKQKVEVDNADIERFFVEDGYLNEDELVERPPVVTIMGHVDHGKTTL
                     LDTLRNSRVATGEAGGITQHIGAYQIVENGKKITFLDTPGHAAFTSMRARGASVTDIT
                     ILVVAADDGVMPQTIEAINHSKAANVPIIVAINKIDKPGANPERVIGELAEHGVMSTA
                     WGGDSEFVEISAKFNQNIEELLETVLLVAEIQELKADPTVRAIGTVIEARLDKGKGAV
                     ATLLVQQGTLNVQDPIVVGNTFGRVRAMTNDLGRRVKVAGPSTPVSITGLNEAPMAGD
                     HFAVYEDEKSARAAGEERAKRALMKQRQATQRVSLENLFDTLKAGELKSVNVIIKADV
                     QGSVEALSASLQKIDVEGVKVTIVHSAVGAINESDVTLAEASNAFIVGFNVRPTPQAR
                     QQAEADDVEIRLHSIIYKVIEEMEEAMKGMLDPEFEEKVIGEAVIRETFKVSKVGTIG
                     GFMVINGKVARDSKVRVIRDGVVIYDGELASLKHYKDDVKEVTNGREGGLMIDGYNDI
                     KMDDVIEAYVMEEIKR"
     gene            11632..11982
                     /gene="rbfA"
                     /locus_tag="VQU30_001836"
     CDS             11632..11982
                     /gene="rbfA"
                     /locus_tag="VQU30_001836"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001273594.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosome-binding factor RbfA"
                     /protein_id="HET2447891.1"
                     /translation="MANHFRTDRVGMEIKREVNEILQKKVRDPRVQGVTITDVQMLGD
                     LSVAKVYYTILSNLASDNQKAQIGLEKATGTIKRELGRNLKLYKIPDLTFVKDESIEY
                     GNKIDEMLRNLDKN"
BASE COUNT         3727 a         2124 c         2746 g         3526 t
ORIGIN      
        1 tacgatttca agaactcctc tcagctctga ggacacggta atgattgatg cgacggaagt
       61 acaaatcaat cgccctaaaa aaagaattag cgaatgattc tggtaaaaag aaatgccacg
      121 ctatgaagac tcaagcgatt gtcacaagtc aagggagaat tgtttctttg gatatcactg
      181 tgaactattg tcatgatatg aagttgttca aaatgagtcg cagaaatatc ggacaagctg
      241 gtaaaatctt ggctgacagt ggttatcaag ggctcatgaa gatatatcct caagcacaaa
      301 cttcacgtaa atccagcaaa ctcaaaccgc taacagttga agataaagcc tgtaaccatg
      361 cgctatctaa ggagagaagc aaggttgaga acatctttgc caaagtaaaa acgtttaaaa
      421 tgttttcaac aacctatcga aatcatcgta aacgcttcgg attacgaatg aatttgagtg
      481 ctggtattat caatcatgaa ctaggattct agttttgcag gaagtctaat gtaatttttg
      541 caattcaaga cgtttcgatg actattcaag atctggatga aaaattttaa aaaacgatga
      601 tatactaaac ttgtcaaagt tacaacaaga caaaaattaa aaataaaaaa gagtatttgt
      661 catggataca aaaattatgg aacaatttca tgaaatggat ataactatgt tatctagtat
      721 tgaaggaggc aagaataatt ggcaaactaa tgtcttggaa ggtggtggtg ctgcttttgg
      781 tggctggggg ctagggacag ctatttgtgc tgcgagtggt gttggagcac catttatggg
      841 agcatgtgga tacataggag ctaaatttgg tgtggatctt tgggcaggag taacaggggc
      901 aacgggtgga ttttaataaa aggagacttg tatgaatact tattgtaata taaatgaaac
      961 aatgctgagt gaggtttatg gaggtaattc cggaggagca gctgtagttg ctgctttagg
     1021 ttgtgcagcg ggtggagtga aatatgggag acttctagga ccatggggcg ctgcaatagg
     1081 aggaattgga ggagcagtgg tttgtggata tttagcctat accgctacat cataaaaatg
     1141 aaagctaaat tttatgaagg ctatattctt tattattctc ttcgcttttc aaacctatct
     1201 tatttatcta tccataagta tctccgataa aaaacaaaag actattgaat taacatcatt
     1261 gaattgtttt gtcatattat ttctaatcta tgataaatta atttttctct ttattgccta
     1321 tgtttttttg ataattttta tattaaactt gttccgtaac tgaaaagtga tatactatat
     1381 ggatacaaaa atgatgtcac aatttgcagt tatggataat gaaatgcttg cttgcgttga
     1441 aggtggagat attgattggg gaagaaaaat tagttgtgca gcaggggttg catatggcgc
     1501 aattgatggg tgtgcaacaa cggtttgaca tttctattgg gaccatttgc tataggaata
     1561 ggtgtaactg gtgctgcagg tggagctata cttggaggtg tagcctatgc agcaatatgt
     1621 tggtggtaat tatggatttt aaaagtttta ttattggttt agtagttggt atatttggtc
     1681 cttatatgga tgacttaatt agaaaaatat tttcaaaatc ttccaaaaag gatacggata
     1741 gtactctcta aaaaataaat ttctcccctg tatttgctag cttaatttac aggggagttt
     1801 ctttaatatt gtttcgcctg tcaaaatgat atgtgatagc aggatgaaaa gtctacaaac
     1861 aagttggtat caatacaata taaagaggaa agtatgtttt taatgcttac tttttaaatt
     1921 ttttaacaat tcaagatgtt tcgatgacaa ttcaagattt ggatgaaaaa ttttaaaaaa
     1981 caatgatata ctaaacttgt caaagttgca acgggtgctg ctacattatg ttaaaaatcg
     2041 ctcttgattg ataagctgga tttgttagga aaggagtaaa taattatgga taagaaaaag
     2101 atagtttcga ctataatatg tatagtattt cttgtagtgt cagtagataa tttttttaga
     2161 gacttaaccc cgttactgtt cattttaaat attattggcc tgtcttgctt ttcagtgcta
     2221 acatacatta acataaaaga gatactctta aatataagta aatgatgatt tggttagtcc
     2281 tagaaccaat caacttatgt ttatcggctt ggcagatttt atgtttgtca tttgtttgta
     2341 tagaggtatt tcagaaacag aattctatca acaactaatc gcttatatag gtgtattctc
     2401 tgcttgttta tcacgcttct gctcatgtgg ggcttgaagt attataaaaa gtagctttct
     2461 atccttttct gacaggatat ttgagtagaa ggctctatta aattgttagt gaaataaatg
     2521 aatggaggta tttaatatga aatacagatt attttttgtt attttcttga gtagtgtgtt
     2581 ggatattctt ttagggacat ttttacaaat ctctatcgta tctattgggt ggcttgttct
     2641 ttacagtggt ttgtttgaag taggagtttt ccttcttgct aataaagggg tggcggtaaa
     2701 aatcaaggaa gtagatattc gaaatcgctt taaatttatt tttggaaaaa ccttatggtt
     2761 tcaaattctt ttgctcatct ttttgataat caaactttat cttggtttgg atgcgaggtt
     2821 gattttattc tatggacata ttttcattgt ctttaatgcc ttaatgtatc tattatctag
     2881 tagtcaggtt agccttaaaa aaaaacaaac tgtcttctta atcttacagc agtagagtct
     2941 gacaaggtga ggtcatagta gggaggattt ctatgaaaaa gtatcaactt ctattcaaaa
     3001 taagtgcagt cttctcttac ttatttttcg tatttggtct ttctcagctg acgcttatcg
     3061 tccaaaatta ttggcaattt tcttcccaga ttggtaattt cgtctggatt caaaatatct
     3121 tgagtttact ttttattgga gtcatgattg tggttcttgt taagacaggc catggttatc
     3181 tcttccgcat tccaagaaaa aaatggcttt ggtattcgat tttgacagta ttagtggtag
     3241 tgttccagat ctcttttaac gttcagacag ctaaacatgt tcagtcaact gcggaaggtt
     3301 gggctgtatt gattggttat agtgggacta actttgcaga gctaggtatt tatatagccc
     3361 tgttctttct ggttccactg atggaagaat tgatttatag aggattactg caacatgctt
     3421 tctttaagca ttcgcgattt ggtcttgatt tgcttcttcc ttctatttta tttgctctcc
     3481 ctcatttttc aagcctgcct agtctgttag atatcttcgt ctttgcaaca gttggaatca
     3541 tctttgctgg tttgacccgc tataccaaga gcatttatcc atcctatgcg gtgcatgtga
     3601 tcaataatat tgtagcgacc ttcccgtttt tgctcacttt tctacatagg gtcttggggt
     3661 aaaaaaacaa aaggcttgct tttcagccat agaggaggtc atcatgtata aacacttatt
     3721 tttcctagat tccaaaactt tagatcggtt gacaccctat attctagtct tggcttctga
     3781 caccattgct tttaatgttt ttgtgctaac ctttgtatct gcggtggttt ttaatttcct
     3841 aaattccatg ctagctttaa tggctatatt cataggggct ggctatgtgg tcggattttg
     3901 gttgctaaaa tggtttgttt tggaaaggtt agagctaaag gatgacgcgt aggaagtctg
     3961 tttggtgagg aggatagttt tatggagttt tttgataaat ttcatgcctt gtgttttgga
     4021 tttttagtac taataattgt cattacagtt ccttatacga ttaaccatgg gggttttttt
     4081 caaaatgaat ctgcattgat tcttgtaagt cttcttgtaa cctcgctgag tgttgcttat
     4141 gctagaaagt ttgaaatgat ttcttttggg atgttaagca agaaacaact tttgcttttc
     4201 attgcaatct ttcttctaag tgtacttgag acgctggttt atattcattt cttcgctgtt
     4261 tcttctggct caggggtcca acacttggcg gaagtcagca gaggaatttc cctgtctttg
     4321 attttgacta cctcagtttt tggccccatc caggaggaac tcattttcag aggacttctt
     4381 caaggtgcgg tttttgacaa ttcttggtta gggcttgtgc taacttcctc tctcttttct
     4441 ttcatgcatg gaccttctaa tgtcccttcg tttatttttt atctacttgg gggtttgttg
     4501 ctgggctttg cttataaaaa gagtcaaaac ctatgggttt ctactctagt acacatgttt
     4561 tacaacagtt ggccactcct atattattta taaaaattat gaaaaggtaa gcagaagacg
     4621 gtgcttacct ttttcaagct ataatgatac ccaagccaat ccagaggctt ttctttgaga
     4681 atcgggttag agtggttgac gaataggcca aaaactagta gaatagtaag gaaactttat
     4741 acggaggaaa gaaatggatt tgggtgataa tgagctaaca ctgactccca tacctgggaa
     4801 aagtggcaag gcttatatgg gtagctatcc tgacgggaag cgcatctttg taaaaatgaa
     4861 cacctctcca atcctacctg gtctagctag agaacaaatt gctccacaat tattatggag
     4921 tcgtcgtttg gcagatgggc gtgatatgtg tgctcaagaa tggttgacag gcaagatatt
     4981 gaccccctat gatatgaatc gtaagcaaat cgtcaatatt ttaacccgtc ttcatcgctc
     5041 acgtccgttg atgacacaat tgagtcgttt gggctatgcc atggaaacac ctgtagattt
     5101 actacagtct tggcaggaaa cggctccaga tgctttgcgt aaaaatcatt ttatcagtga
     5161 agtgatggct gatttacgtc agactattcc aggatttaga gaggaccatg cgaccattgt
     5221 ccatggagat gtacgacata gtaattggat tgagacagat agtggcttga tttatttagt
     5281 agattgggat tcggttcgct tgaccgatcg catgtttgat gtggcccata tgctctgcca
     5341 ttatatttca gaacatcagt ggaaggaatg gttgacctac tacggttaca agtacaatca
     5401 aacggtatta agtaaattgt attggtatgg tcaattgtct tatttgagtc agatttccaa
     5461 gtattatatg aaccaagatt tagaaaatgt caatcgggag attcatggtt tgcgtcattt
     5521 ccgagacaag tatggaaaga gaagatgaga gttagaaatc gtaaaggggc aacagaatta
     5581 ctagaggcaa atccccagta tgtggtcctc aatcccttgg aagccaaggc aaaatggcgg
     5641 gacttgtttg gcaatgataa tcccattcat gtggaagttg gaagtggaaa gggtgccttt
     5701 gtttcaggta tggccaagca aaaccctgac atcaactata tcgggattga tattcaaaag
     5761 tctgttttga gctacgcttt ggacaaggtg cttgaagttg gagtgcctaa catcaagctc
     5821 ttgtgggtag atggttctga cttaactgac tattttgaag acggtgagat tgatcgcttg
     5881 tatctgaact tttcagatcc atggccgaaa aaacgccatg aaaagcgtcg tttgacctac
     5941 aagaccttct tggatacctt caaacgtatc ttgcctgaaa atggagaaat tcatttcaag
     6001 acggataacc gtggcttgtt tgagtacagt ttagtgagct tttctcaata tggcatgaaa
     6061 ctcaatggtg tctggttaga tttgcatgcc agtgattttg aaggcaatgt catgacagaa
     6121 tacgagcaaa aattctcaaa caaggggcaa gttatctacc gagttgaggc agaattttaa
     6181 gagatagcct aaaattaggc tgtacaagtg cttttgcttt acataagttg gcaaacgtgc
     6241 tatactgata gtaagaatat gaaaagtgag gcggggaaat atcttcgcct cttgcttatg
     6301 aggaggtgga cgcaatcgca acaatcgtag aattagtcag agaagttgta gaacctgtca
     6361 tagaagctcc ttttgaactc gtggatatcg agtatggaaa gattggcagt gacatgattc
     6421 tcagtatttt tgtagataaa cccgaaggaa ttaccttgaa cgacacggca gacttgacag
     6481 aaattatcag tcctgtccta gacaccatca agccagatcc cttcccagaa caatatttcc
     6541 tagaaattac cagtccaggt ttggaacgcc ctttgaaaac caaggatgcc gtcgctggag
     6601 cggttggaaa atacatccat gtcgggctct accaagccat cgataagcaa aaggtctttg
     6661 aaggaacctt gttggccttc gaagaggacg agttgactat ggaatatatg gacaagacgc
     6721 gtaagaaaac cgtccaaatt ccatacagtt tagtatcaaa agcacgttta gcagttaaat
     6781 tatagaaaaa gaaaggatag cttttgagga ttcaaaagtg aagaaaacat gagtaaagaa
     6841 atgctagagg ccttccgcat tttggaagaa gacaagggaa tcaaaaaaga agatatcatc
     6901 gacgcagtag tagagtcgct tcgttccgct tatcgcagac gctatggtca gtcagacagc
     6961 gtagctattg acttcaacga aaaaacaggt gactttacag tttatactgt ccgtgaagtt
     7021 gttgatgaag tatttgatag ccgtttggaa atcagcttga aagatgctct tgccattaat
     7081 tcagcttatg aacttggaga caaaatcaag tttgaagaag caccagctga gtttggtcgt
     7141 gtagcagccc agtctgccaa acaaaccatc atggaaaaaa tgcgcaagca aacacgtgcc
     7201 atcacttaca atacttacaa agaacatgag caagaaatca tgtctggtac agtagaacgc
     7261 tttgacaacc gctttatcta tgtcaacctt ggtagcatcg aagcccaatt gtcaaaacaa
     7321 gaccaaattc ctggagaagt ttttgcttct catgatcgta tcgaagttta tgtttacaag
     7381 gttgaagaca accctcgtgg tgtgaacgtc tttgttagcc gtagtcatcc agaaatgatc
     7441 aaacgtttaa tggagcaaga aattccagaa gtttatgatg gaactgttga aatcatgagc
     7501 gtggctcgtg aagcaggtga ccgtacgaag gttgctgttc gtagccacaa tccaaacgtg
     7561 gatgctatcg gtacaatcgt tggacgtggt ggtgctaata tcaagaagat tactagcaaa
     7621 ttccacccag ctcgttacga tgctaaaaat gaccgcatgg taccaatcga agaaaatatc
     7681 gatgttatcg agtgggtagc agatccagct gaatttatct acaatgccat cgctcctgct
     7741 gaggttgacc aagttatctt tgatgaaaac gacagcaaac gtgccttggt ggttgttcca
     7801 gataacaagc tttctcttgc cattggtcgt cgtggacaaa acgtgcgctt ggcggctcac
     7861 ttgactggtt accgtatcga tatcaagtct gctagcgaat ttgaagccat ggaagacgct
     7921 gcttcagtag agttggaagt agaaaacgat actgtagaag aataaaagct gctagaggag
     7981 ggaaagatga aaacaagaaa aatccctttg cgcaagtctg ttgtgtctaa cgaagtcatt
     8041 gataagcgtg atttgctccg cattgtcaag aacaaggaag gacaagtctt tattgatcct
     8101 acgggcaagg ccaatggccg cggcgcttat atcaaactag acaatgcaga agccctagag
     8161 gcgaaaaaga agaaggtctt taaccgcagc tttagcatgg aagtggaaga aagcttttat
     8221 gacgagttga tcgcttatgt ggatcacaaa gtgaaaagaa gagagttggg acttgaataa
     8281 gcaaaagata agtaatctct tggggcttgc tcagcgagca gggcgcatca tatcgggtga
     8341 agaattggtg gtcaaggcca ttcaagacgg caaggccaag ttggtctttc tagctcatga
     8401 tgctggaccc aatctgacca agaagattca agataaaagt cattattatc aagtagaaat
     8461 tgtaaccgtg ttttcaacac tggaattaag catagcagtc gggaaatcga gaaaggtttt
     8521 ggctgtaaca gatgctggat ttacaaagaa aatgaggtct cttatggaat agaagaggag
     8581 gacatgattt gtctaagaaa agattgtacg aaatcgcaaa agaacttgga aaagaaagta
     8641 aagaagttgt agcgcgtgca aaagagttgg gcttggatgt gaaaagccac tcatcaagtg
     8701 tggaagaagc tgtcgctgca aaaattgctg ccagctttaa gcctgcagct gctccgaaag
     8761 tagaagcaaa acctgcagca ccaaaagtaa gtgcagaaaa gaaagccgaa aaatctgagc
     8821 cagctaaacc agctgtagct aaggaagagg caaaaccggc tgagccagtt gctccgaaaa
     8881 cagaaaaagt agcagtgaaa ccgcaaagtc gtaatttcaa ggctgagcgt gaagcccgtg
     8941 ctaaagagca ggcagaacga cgcaagcaaa ataagggcaa taaccgtgac caacaacaaa
     9001 acggaaaccg tcagaaaaac gacggccgta atggtggaaa acaaggtcaa agcaaccgcg
     9061 acaatcgtcg ctttaatgac caagctaaga agcagcaagg tcagcaaaaa cgtagaaatg
     9121 agcgccgtca gcaagaggat aaacgttcaa atcaagcggc tccacgtatt gactttaaag
     9181 cccgtgcagc agccctaaaa gcagagcaaa atgcagagta cgctcgttca agtgaggaac
     9241 gcttcaagca gtatcaggct gctaaagaag ccttggctca agctaacaaa cgcaaggaac
     9301 cagaggaaat ctttgaagaa gcggctaagt tagctgaaca agcacagcaa gttcaagcag
     9361 tggttgaagt cgtccctgag aaaaaagaac ctgcagtgga tacacgtcgt aaaaaacaag
     9421 ctcgaccaga caaaaatcgt gacgattatg atcatgaaga agatggtcct agaaaacaac
     9481 aaaagaatcg aagtagtcaa aatcaagtga gaaatcaaaa gaatagtaac tggaataaca
     9541 acaaaaagaa caaaaaaggc aataacaaga acaaccgtaa tcagactcca aaacctgtta
     9601 cggagcgtaa attccatgaa ttgccaacag aatttgaata tacagatggt atgaccgttg
     9661 cggaaatcgc aaaacgtatc aaacgtgaac cagctgaaat cgttaagaaa cttttcatga
     9721 tgggtgtcat ggccacacaa aaccaatcct tggatgggga aacaattgaa ctcctcatgg
     9781 tggattacgg tatcgaagcc aaacaaaagg ttgaagtgga taatgctgac atcgaacgtt
     9841 tctttgtcga agatggttat ctcaatgaag atgaattggt tgagcgtcca ccagttgtta
     9901 ctatcatggg acacgttgac cacggtaaaa caaccctttt ggatactctt cgtaactcac
     9961 gtgttgcgac aggtgaagca ggtggtatta ctcagcatat cggtgcctac caaatcgtgg
    10021 aaaatggtaa gaagattacc ttccttgata caccaggaca cgcggccttt acatcaatgc
    10081 gtgcgcgtgg tgcttctgtt accgatatta cgatcttggt cgtagcggca gatgacgggg
    10141 ttatgcctca gactattgaa gccatcaacc actcaaaagc agctaacgtt ccaatcatcg
    10201 tagccattaa caagattgat aaaccaggtg ctaacccaga acgcgttatc ggtgaattgg
    10261 cagagcatgg tgtgatgtca accgcttggg gtggagattc tgaatttgtt gaaatctcag
    10321 ctaaattcaa ccaaaatatc gaagaattgt tggaaacagt ccttcttgta gctgaaatcc
    10381 aagaactcaa ggcagaccca acagtgcgtg caatcggtac ggttatcgaa gcgcgcttgg
    10441 ataaaggaaa aggtgcggtc gcaacccttc ttgtacaaca aggtaccttg aatgttcaag
    10501 acccaatcgt tgtcggaaat accttcggtc gtgtccgtgc tatgaccaac gaccttggtc
    10561 gtcgtgttaa agttgctgga ccatcaacac cagtctctat cacaggtttg aacgaagcac
    10621 cgatggcggg tgaccacttt gccgtttacg aggatgaaaa atctgcgcgt gcagcaggtg
    10681 aagagcgtgc caaacgtgcc ctcatgaaac aacgtcaagc tacccaacgt gttagccttg
    10741 aaaacctctt tgataccctt aaagctgggg aactcaaatc tgttaatgtt atcatcaagg
    10801 ctgatgtaca aggttctgtt gaagcccttt ctgcctcact tcaaaagatt gacgtggaag
    10861 gtgtcaaagt gactatcgtc cactcagcgg tcggtgctat caacgaatca gacgtgaccc
    10921 ttgccgaagc ttcaaatgcc tttatcgttg gtttcaacgt acgccctaca ccacaagctc
    10981 gtcaacaagc agaagctgac gatgtggaaa tccgtcttca cagcattatc tacaaggtta
    11041 tcgaagagat ggaagaagct atgaaaggga tgcttgatcc agaatttgaa gaaaaagtta
    11101 ttggtgaagc ggttatccgt gaaaccttca aggtgtctaa agtgggaact atcggtggat
    11161 ttatggttat caacggtaag gttgcccgtg actctaaagt ccgtgttatc cgtgatggtg
    11221 tcgttatcta tgatggtgaa ctcgcaagct tgaaacacta taaagacgac gttaaggaag
    11281 ttacaaacgg ccgtgaaggt ggattgatga tcgacggcta caatgatatt aagatggatg
    11341 atgtgattga ggcgtatgtc atggaagaaa tcaagagata agattttttg ctcctttctt
    11401 aggtggtgag ggacgcaagc aaaccgatgg tttcattgct tatttttgag cctagggtct
    11461 caaaaatccc ctgtgatggg actgataaat cagttccatc actttcacca cggcgaaaga
    11521 agcagatgac ttcaaattga acttcgtttc aatttaaact gaaaatcaag aagtttaaaa
    11581 tagctaggtc tgctggccta gcttttggtt caaagtagag aaaggaatat catggcaaat
    11641 catttccgta cagatcgtgt gggcatggaa atcaagcgtg aagtcaatga gattttgcaa
    11701 aagaaagtcc gtgatccacg tgtccaaggt gtgaccatca cagatgttca gatgctgggt
    11761 gacttgtctg ttgccaaggt ttattacacc attttgagta accttgcttc ggataaccaa
    11821 aaagcccaaa tcgggcttga aaaagcaact ggtaccatca aacgtgaact tggtcgcaat
    11881 ttgaaattgt acaaaatccc agatttgacc ttcgtcaaag acgagtccat cgagtatgga
    11941 aacaagattg acgagatgct acgcaatctg gataagaact aaagaagagg ggttgcccct
    12001 ctttttcggc tctttgtcaa ctgtagtggg ttgaagaaaa gctaagctcg agaaaggaca
    12061 aatttcgtcc tttctttttt gatattcagg gcgataaaaa tccgtttttt gaagttttca
    12121 aag
//
LOCUS       DAVBBO010000062        11272 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ST1
            SAMEA2066453-rid20184263.denovo.062, whole genome shotgun sequence.
ACCESSION   DAVBBO010000062 DAVBBO010000000
VERSION     DAVBBO010000062.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2066453
            Sequence Read Archive: ERR351777
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 11272)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11272)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980402.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980402.1
            Genome Coverage       :: 176x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:17:33
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,141
            CDSs (total)                      :: 2,104
            Genes (coding)                    :: 1,953
            CDSs (with protein)               :: 1,953
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 16S)
            partial rRNAs                     :: 1 (23S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 151
            CDSs (without protein)            :: 151
            Pseudo Genes (ambiguous residues) :: 0 of 151
            Pseudo Genes (frameshifted)       :: 73 of 151
            Pseudo Genes (incomplete)         :: 76 of 151
            Pseudo Genes (internal stop)      :: 40 of 151
            Pseudo Genes (multiple problems)  :: 32 of 151
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11272
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2066453-rid20184263.denovo.062"
                     /strain="ST1"
                     /db_xref="taxon:1313"
     gene            complement(<1..947)
                     /locus_tag="VQU30_001837"
     CDS             complement(<1..947)
                     /locus_tag="VQU30_001837"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001083019.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HET2447892.1"
                     /translation="MNRYAVQLISRGAINKMGNMLYDYGNSVWLASMGTIGQTVLGMY
                     QISELVTSILVNPFGGVISDRFSRRKILMTADLVCGILCLAISFIRNDSWMIGALIVA
                     NIVQVIAFAFSRTANKAIITEVVEKDEIVIYNSRLELVLQVVGVSSPVLSFLVLQFAS
                     LHMTLLLDSLTFFIAFILVTFLPKEEAKVQEKKAFTGRDIFVDIKDGLHYIWHQQEIF
                     FLLLVASSVNFFFAAFEFLLPFSNQLYGSEGAYASILTMGAIGSIIGALLASKIKANI
                     YNLLILLALTGVGVFMMGLPLPTFLSFSGNLVCELFMTI"
     gene            complement(1027..1890)
                     /locus_tag="VQU30_001838"
     CDS             complement(1027..1890)
                     /locus_tag="VQU30_001838"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012291596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="XRE/MutR family transcriptional regulator"
                     /protein_id="HET2447893.1"
                     /translation="MEHLGKVFREFRTSGNYSLKEAAGESCSTSQLSRFELGESDLAV
                     SRFFEILDNIHVTIENFMDKARNFHNHEHVSMMAQIIPLYYSNDIAGFQKLQREQLEK
                     SKSSTTSLYFELNWILLQGLICQRDASYDMKQDDLDKVADYLFKTEEWTMYELILFGN
                     LYSFYDVDYVTRIGREVMEREEFYQEISRHKRLVLILALNCYQHCLEHSSFYNANYFE
                     AYTEKIIDKGIKLYERNVFHYLKGFALYQKGQCKEGCKQMQEAMHIFDVLGLPEQVAY
                     YQEHYEKFVKS"
     gene            complement(1893..3794)
                     /locus_tag="VQU30_001839"
     CDS             complement(1893..3794)
                     /locus_tag="VQU30_001839"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000584877.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HET2447894.1"
                     /translation="MIILQANKIERSFAGEVLFDNINLQVDERDRIALVGKNGAGKST
                     LLKILVGEEEPTSGEINKKKDISLSYLAQDSRFESENTIYDEMLHVFNDLRRTERQLR
                     QMELEMGEKSGEDLDKLMSDYDRLSENFRQAGGFTYEADIRAILNGFKFDESMWQMKI
                     AELSGGQNTRLALAKMLLEKPNLLVLDEPTNHLDIETISWLENYLVNYSGALIIVSHD
                     RYFLDKVATITLDLTKHSLDRYVGNYSRFVELKEQKLATEAKNYEKQQKEIAALEDFV
                     NRNLVRASTTKRAQSRRKQLEKMERLDKPEAGKKAANMTFQSEKTSGNVVLTVENAAV
                     GYDGEVLSQPINLDLRKMNAVAIVGPNGIGKSTFIKSIVDQIPFIKGEKRFGANVEVG
                     YYDQTQSKLTPSNTVLDELWNDFKLTPEVEIRNRLGAFLFSGDDVKKSVGMLSGGEKA
                     RLLLAKLSMENNNFLILDEPTNHLDIDSKEVLENALIDFDGTLLFVSHDRYFINCVAT
                     HVLELSENGSTLYLGDYDYYVEKKATAEMSQTEEASTSNQAKEASPVNDYQAQKESQK
                     EVRKLMRQIESLEAEIEELESQSQAISEQMLETNDADKLMELQAELDKISHRQEEAML
                     EWEELSDQV"
     gene            complement(4222..4497)
                     /locus_tag="VQU30_001840"
     CDS             complement(4222..4497)
                     /locus_tag="VQU30_001840"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002950996.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HU family DNA-binding protein"
                     /protein_id="HET2447895.1"
                     /translation="MANKQDLIAKVAEATELTKKDSAAAVEAVFAAVADYLAAGEKVQ
                     LIGFGNFEVRERAERKGRNPQTGKEMTIAASKVPAFKAGKALKDAVK"
     gene            complement(4603..5442)
                     /locus_tag="VQU30_001841"
     CDS             complement(4603..5442)
                     /locus_tag="VQU30_001841"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000161411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HET2447896.1"
                     /translation="MTKIKIVTDSSVTIEPELVKQLDITIVPLSVMIDNVVYSDADLK
                     EEGKFLQLMQESKNLPKTSQPPVGVFAEIFEDLCKDGGQILAIHMSHALSGTVEAARQ
                     GASLSTADVIVVDSSFTDQALKFQVVEAAKLAQEGKDMEAILSHVEEVKNHTELYIGV
                     STLENLVKGGRIGRVTGLLSSLLNIRVVMQMKDHELQPMVKGRGTKTFKKWLDELITS
                     LSERAVAEIGISYSGSDDWAKEMKESLQAYVEKPISVLETGSIIQTHTGENAWAILIR
                     YHS"
     gene            5584..6432
                     /locus_tag="VQU30_001842"
     CDS             5584..6432
                     /locus_tag="VQU30_001842"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000592058.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HET2447897.1"
                     /translation="MIKKIYPIFTILLGAAIYAFGLTYFVVPHHLFEGGATGITLITF
                     YLFKIPVSLMNLLINIPLFILAWKIFGAKSLYSSLLGTLALSGWLAFFEHIPLHIDLQ
                     GDLLITALIAGILLGIGLGIIFNAGGTTGGTDILARILNKYTHISIGKLLFILDFCIL
                     MLILLIFKDLRLVSYTLLFDFIVSRVIDLIGEGGYAGKGFMIITKRPDQLAKAINDDL
                     GRGVTFISGQGYYSKENLKIIYCIVGRNEIVKTKEMIHRIDPQAFITITEAHEILGEG
                     FTFEKE"
     gene            complement(6525..7442)
                     /locus_tag="VQU30_001843"
     CDS             complement(6525..7442)
                     /locus_tag="VQU30_001843"
                     /EC_number="2.7.1.26"
                     /EC_number="2.7.7.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000587449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional riboflavin kinase/FAD synthetase"
                     /protein_id="HET2447898.1"
                     /translation="MIITIPIKNQKDIGTPSDSVVVLGYFDGIHKGHQELFRVANKAA
                     RKDLLPIVVMTFNESPKIALEPYHPDLFLHILNPAERERKLKREGVEELYLLDFSSQF
                     ASLTAQEFFATYIKAMNAKIIVAGFDYTFGSDKKTAEDLKDYFDGEVIIVPPVEDEKG
                     KISSTRIRQAILDGNVKEAGKLLGAPLPSRGMVVHGNARGRTIGYPTANLVLLDRTYM
                     PADGVYVVDVEIQRQKYRAMASVGKNVTFDGEEARFEVNIFDFNQDIYGETVMVYWLD
                     RIRDMTKFDSVDQLVDQLKADEEVTRNWS"
     gene            7879..8084
                     /locus_tag="VQU30_001844"
                     /pseudo
     CDS             7879..8084
                     /locus_tag="VQU30_001844"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844775.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
     gene            complement(8395..8688)
                     /gene="rpmA"
                     /locus_tag="VQU30_001845"
     CDS             complement(8395..8688)
                     /gene="rpmA"
                     /locus_tag="VQU30_001845"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018376869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L27"
                     /protein_id="HET2447899.1"
                     /translation="MLKMTLNNLQLFAHKKGGGSTSNGRDSQAKRLGAKAADGQTVTG
                     GSILYRQRGTHIYPGVNVGRGGDDTLFAKVEGVVRFERKGRDKKQVSVYPIAK"
     gene            complement(8705..9049)
                     /locus_tag="VQU30_001846"
     CDS             complement(8705..9049)
                     /locus_tag="VQU30_001846"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000613691.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosomal-processing cysteine protease Prp"
                     /protein_id="HET2447900.1"
                     /translation="MIQAVFERAEDGELRGAEITGHAESGEYGLDVVCASVSTLAINF
                     INSIEKFAGYEPILELNEDEGGYLMVEIPKDLPSHQREMTQLFFESFFLGMANLSENY
                     SEFVQTRVITEN"
     gene            complement(9065..9379)
                     /gene="rplU"
                     /locus_tag="VQU30_001847"
     CDS             complement(9065..9379)
                     /gene="rplU"
                     /locus_tag="VQU30_001847"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018374562.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L21"
                     /protein_id="HET2447901.1"
                     /translation="MSTYAIIKTGGKQVKVEVGQAVYIEKLNVEAGQEVTFNEVVLVG
                     GENTVVGTPLVAGATVVGTVEKQGKQKKVVTYKYKPKKGSHRKQGHRQPYTKVVINAI
                     NA"
     misc_feature    complement(9415..9502)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00559"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="ribosomal protein L21 leader region; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /db_xref="RFAM:RF00559"
     gene            complement(9597..10196)
                     /locus_tag="VQU30_001848"
     CDS             complement(9597..10196)
                     /locus_tag="VQU30_001848"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001858962.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1275 domain-containing protein"
                     /protein_id="HET2447902.1"
                     /translation="MTFCAGYVDAYTFIVRGNTLVAGQAGNVVFLSVELIQNNVSDVR
                     DKLLTLITFIMGVFLLTIYKEKLRIVKKPILSLIPLAILSIIIGFVPQTVDNIYLVQP
                     LAFCMGLVTTAFGEVSGIAYNNAFMTGNIKRTMLAFGDYFRTKHTPFLREGFIFVSLL
                     SSFVLGDVFSAYLTIFYHEKTILGVPIMMSIFYLSMLFA"
     gene            10666..10965
                     /locus_tag="VQU30_001849"
     CDS             10666..10965
                     /locus_tag="VQU30_001849"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008808250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YbaB/EbfC family nucleoid-associated protein"
                     /protein_id="HET2447903.1"
                     /translation="MMNMQNMMRQAQKLQKQMEQSQAELAAMQFVGKSAQDLVQATLT
                     GDKKVVSIDFNPAVVDPEDLETLSDMTVQAINSALEQIDETTKKKLGAFAGKLPF"
BASE COUNT         3573 a         2333 c         1870 g         3496 t
ORIGIN      
        1 aaaatcgtca taaacaattc acaaactaaa tttccagaaa aggaaagaaa agttggaagt
       61 ggtaatccca tcataaaaac tccgacacct gtcaaagcca gtaaaatcaa aagattataa
      121 atattagctt taattttact agctagaaga gccccaatga tggaaccaat agcccccata
      181 gttaaaatac ttgcataggc tccttctgac ccgtaaagct gattcgaaaa gggaagtaga
      241 aattcaaaag ctgcaaaaaa gaaattaacg ctggaagcta ccagcaaaag gaagaaaatt
      301 tcttgctgat gccagatata gtgtaaccca tccttgatat ctacaaaaat atctctccca
      361 gtaaaagcct ttttctcttg aacttttgct tcctcttttg gaaggaaagt cactagaata
      421 aaagcaatga aaaaagtcag cgagtctagc agtagcgtca tatggagact tgcaaactgt
      481 aaaacaagga aggaaagaac aggagagcta acacctacaa cctgcaaaac cagctctaag
      541 cgagaattat agatcacaat ctcatctttc tccaccactt cagttatgat agctttattg
      601 gctgtgcgag aaaaggcaaa agcaataacc tgcacaatgt tagcaacaat caaagcgcca
      661 atcatccagc tatcattcct tatgaaagaa atagccagac aaagaatccc acaaacaaga
      721 tctgccgtca ttaaaatctt acgacgagaa aaacggtctg aaataactcc gccaaaggga
      781 ttgacgagaa tagatgtgac gagctcagaa atctgataca ttcctaaaac tgtctgtcct
      841 atagtcccca tagaagccaa ccagacacta tttccataat catagagcat atttcccatt
      901 ttattgatag ccccacggct aatcaactgc actgcatagc gattcatatt aaagctcctc
      961 tcaaattttg aaactattgt atcaaaaccg aaaggagctt tttatttttt cccttatttg
     1021 ggaaaattaa cttttgacaa atttttcgta gtgttcctga taataggcta cttgctctgg
     1081 aagacctaac acatcaaaaa tatgcatggc ctcttgcatc tgcttacagc cttctttaca
     1141 ctgtcctttt tgatataagg caaaaccttt taaataatgg aaaacattac gctcataaag
     1201 cttaatacct ttgtcaataa tcttctctgt ataagcctca aaatagttgg cattataaaa
     1261 agaagaatgc tctaaacaat gctggtaaca attgagggcc aaaatcaaca ctaatctctt
     1321 atggcgacta atctcttggt aaaattcctc cctctccata acttctctac caatccgagt
     1381 gacatagtct acatcgtaga aactatagag gttaccgaaa agaatcaact catacatggt
     1441 ccattcttct gttttgaaga gataatctgc taccttatcc aaatcatcct gcttcatatc
     1501 ataactcgca tctctttgac aaatcagacc ttgtagcaaa atccagttca gctcaaaata
     1561 aagggaagtc gtcgaactct tagacttttc aagttgttct ctttgaagct tttgaaaacc
     1621 tgcaatatcg tttgaatagt aaagtgggat aatctgtgcc atcatagaca catgttcatg
     1681 attatgaaaa ttccttgcct tatccatgaa attttcgatt gttacatgaa tgttatccaa
     1741 aatctcaaag aaacgggaga ctgccaggtc agactcccca agctcaaagc gagataactg
     1801 agaggtagag caggattcgc ctgctgcttc ctttaaagaa taatttccac ttgttcgaaa
     1861 ttcacgaaat acttttccaa gatgttccat ctttacacct gatctgataa ttcttcccac
     1921 tcaagcatag cttcttcctg acgatggctg attttatcca gctcagcctg taattccatg
     1981 agtttgtcgg catcgtttgt ttccaacatt tgttcagaaa tggcttggct ttgactttct
     2041 agctcttcaa tttcagcttc tagactttcg atttgtcgca tgagtttgcg aacttctttt
     2101 tgactttctt tctgggcctg atagtcattg actggacttg cttcctttgc ttgattgcta
     2161 gttgaagctt cctcagtctg actcatttct gctgttgctt tcttctcaac atagtagtcg
     2221 taatctccaa ggtagagagt tgaaccattc tcagacaatt ccaaaacatg agttgccaca
     2281 caattgataa agtaacgatc atgactgaca aaaagcaagg taccatcaaa gtcaatcaag
     2341 gcattttcta gcacttcctt actatcaata tccaagtggt tggtcggctc atccagaatc
     2401 aaaaagttat tgttttccat agacaattta gctaaaagca aacgagcttt ttcgccacca
     2461 gatagcatgc cgactgattt tttaacatca tctcctgaga aaaggaaggc tccaagacgg
     2521 ttgcggattt caacttctgg tgtcaatttg aaatcattcc agagttcatc cagcaccgta
     2581 ttacttggtg tcagcttgct ttgggtttgg tcatagtaac caacctcaac attagcgcca
     2641 aagcgctttt ctcccttgat aaacggaatt tgatccacga ttgatttgat aaaggttgat
     2701 tttccgatac cattgggacc aacgatagca acagcattca tcttacgaag gtctaggtta
     2761 atcggttgtg acaggacttc cccatcatag ccaacagccg cattttcaac agtcaaaaca
     2821 acattgcccg acgttttttc agactggaag gtcatgttgg ctgctttctt gccagcttcc
     2881 ggcttgtcca aacgctccat tttttctagt tgtttacggc gagattgagc acgtttggtc
     2941 gttgaagcac gaactagatt gcgattgaca aagtcttcca gagcagcgat ttccttctgt
     3001 tgcttttcat agttttttgc ctcagtagct agcttttgct ccttcaactc gacaaaacga
     3061 gagtaattcc ccacatagcg atccaaggaa tgcttggtca aatctagcgt aattgtcgca
     3121 accttgtcca agaaataacg gtcgtggctg acgataatga gggcaccgct atagtttacc
     3181 aagtaattct ctagccagga gatggtttca atatccaagt ggttagttgg ctcgtccaag
     3241 accaagagat tgggcttttc aaggagcatt ttagctagag ccaaacgagt attttgacca
     3301 cctgaaagtt cagctatttt catctgccac atagactcgt caaacttgaa tccattcaaa
     3361 atcgctcgaa tatcagcttc ataggtaaag ccacctgctt ggcgaaaatt ctcagataag
     3421 cggtcataat ctgacatcag tttatccaaa tcctcaccag acttttcacc catctccagc
     3481 tccatctgac gcagttgtct ctccgtccga cgcaaatcat taaagacatg aagcatttca
     3541 tcgtagatgg tattttcaga ctcaaaacgg ctatcttggg ctaggtaaga cagagaaata
     3601 tcttttttct tattgatttc tccgctagtt ggctcctctt ctccaactaa aatcttcaaa
     3661 agagtagact tacctgcacc atttttccca acaagagcaa tccgatctcg ttcatcaacc
     3721 tgcaggttga tattatcgaa aagaacctct cctgcaaaag aacgttcaat tttattagct
     3781 tgtaaaataa tcataagagt agtatagcat gtttccctaa ggcattcaag ataatcgtaa
     3841 gtcttttagt acaactttta taacataaaa taaactaaat tatgtatatt ttatattaga
     3901 ttccttcact atcttgttgg attttctaac cagctaatct tgtttcaaat agttatcgca
     3961 caagcctatt atttaattct tttcattatt tacgtacgcg tatagcagat tgaaataaga
     4021 tgagaacaaa tcgattggga aagtaaaatt aatttctata aatgttttag caattgtttc
     4081 gtactatttt agattcagtc tactatgtac aatattttcg gaacattcaa ctttttaact
     4141 ctatttatta ctagatttca taattaaaaa gcctactgac caagctagaa agcttgatac
     4201 aataggcttt ttaaagactg attatttaac agcgtcttta agagctttac cagctttgaa
     4261 tgctggtact ttagaagctg caattgtcat ttctttacca gtttgtgggt tgcgaccttt
     4321 acgttctgca cgctcacgaa cttcaaagtt accaaaaccg atcaattgaa ctttttcacc
     4381 agctgcaaga tagtcagcta ctgctgcaaa tacagcttca actgctgctg ctgagtcttt
     4441 cttagtcaat tctgtagctt ctgctacttt agcgatcaaa tcttgtttgt ttgccatgtt
     4501 aatgattcct ccagataatt tctaattaac aaatataatc atatcctaaa atccctttta
     4561 ggtcaagtta aaaacgctat ttcttccaat tttatttatt ttttaggagt ggtaacgtat
     4621 caaaatagcc caagcgttct cacccgtgtg agtttgaata atggaacccg tttccaaaac
     4681 agaaattggc ttttcaacat aagcttgtaa gctttctttc atctcttttg cccaatcatc
     4741 actaccagaa tatgaaattc caatctctgc tacagcacgt tcagaaagcg atgttatcaa
     4801 ctcatctaac cattttttaa atgttttagt tccacgacct ttaaccattg gctgcaattc
     4861 atggtctttc atttgcatga caacacggat attgagaagg gagctcaaca agccagttac
     4921 acggccaatt cgtccacctt tgacaagatt ttccaaagtt gaaacaccaa tataaagctc
     4981 tgtatggttt ttaacctctt ctacatgaga taaaattgcc tccatatctt taccttcttg
     5041 agctaacttc gcagcctcaa caacttggaa tttcagggct tggtcagtga aggaactatc
     5101 aacaacaatc acatctgcag tagataggct agcaccttgg cgtgctgctt ctaccgtacc
     5161 cgaaagagca tgggacatat gaatagcaag aatctggcca ccatctttgc ataggtcttc
     5221 aaaaatctca gcaaagacac ctacaggtgg ctgacttgtt ttcggaagat tcttactttc
     5281 ttgcatcaac tgaagaaatt taccttcttc tttcaaatcc gcatcagaat aaacaacatt
     5341 atcaatcatt acagataatg gaacaattgt aatatctaat tgctttacta gttcaggttc
     5401 aatagtaaca gatgaatcgg ttacaatctt aatttttgtc atagtatcaa tctttctatt
     5461 ttaggattca gattggtttc cttacttcta attatatcaa aaaaaagatt aaaaatccta
     5521 atggagtcaa tcaaattttc cgtaaaattt gatataatca acttataaga aaagaggtgt
     5581 cctatgatta aaaaaattta ccccattttt accattttac taggtgctgc tatttatgct
     5641 tttggactga cttattttgt agttccccat catctctttg aaggaggggc gacaggtatt
     5701 accctcatca cattttatct ttttaaaatc cctgtttccc tcatgaacct gctgattaat
     5761 attccccttt tcatcctagc ttggaagatc tttggagcca aatccctcta ttctagttta
     5821 ctaggaacct tagctttgtc cggctggtta gctttttttg agcatattcc ccttcatatt
     5881 gatcttcaag gtgatttact aataacagcc cttatagcgg gaatcctatt gggaattggc
     5941 cttggaatta tttttaatgc tggaggtaca actggcggaa ctgatattct agctcgtatt
     6001 ctcaacaaat acactcatat atccatagga aaactgctct ttatcttaga tttttgtatt
     6061 ctcatgttga ttctcctaat cttcaaggat ttgagattgg tttcctacac gcttttgttt
     6121 gattttattg tttctcgtgt tattgatttg attggtgaag gaggatatgc cggcaaaggc
     6181 tttatgatta tcacaaaacg tcctgaccaa cttgctaagg cgattaatga tgacctcgga
     6241 agaggtgtta cttttatttc tggtcaaggc tactatagta aagaaaattt gaaaatcatc
     6301 tactgtattg tcggaagaaa tgaaattgtg aaaacgaagg aaatgattca tcgaatcgat
     6361 cctcaagcct ttataactat tacagaagcc catgaaatcc taggagaagg cttcaccttt
     6421 gaaaaagaat aaaaagaggt aatgtcgtga cctcaaaagt tagactaaat catctatctt
     6481 ttgggttaca gacaacctct tttttgtttt atttactcaa gctcttaaga ccaattccga
     6541 gttacttctt catcagcctt taactgatcc actaattggt caactgagtc aaatttggtc
     6601 atatcacgaa tgcgatcaag ccaataaacc atgacggttt ccccataaat atcttgatta
     6661 aaatcaaaaa tattgacttc aaaacgtgct tcttctccat caaaggtcac atttttcccg
     6721 acactagcca tagcacgata cttctgtctt tgaatctcaa catcaacgac ataaacgcca
     6781 tctgctggca tataagtacg gtctaaaagc actaaattcg ctgtcggata accaattgta
     6841 cgaccacgag cattaccatg aaccaccata cctcttgatg gaagcggtgc ccccaaaagt
     6901 tttcctgctt ctttcacatt tccatctaaa atagcttgac ggatacgagt tgaactaatc
     6961 tttcctttct catcttctac aggtggaaca atgataactt ctccatcaaa gtaatccttt
     7021 aaatcttctg ctgttttttt gtcagaacca aatgtataat caaaacctgc aacaataatt
     7081 ttggcattca tagccttgat ataagttgca aagaattctt gtgcagtgag actagcgaat
     7141 tgactactaa aatcaaggag atataattct tctacacctt cgcgctttaa ttttctttca
     7201 cgttcagcag ggttcaaaat atgcaaaaac aaatccggat gataaggctc taaagcgatc
     7261 tttggagatt cattaaaggt cataacgacg ataggtaata aatcctttct cgcagccttg
     7321 ttggcaacac gaaataattc ttgatgcccc ttatgtatgc catcaaaata gccgagaaca
     7381 acgactgaat cagatggtgt gccaatatct ttttggtttt ttataggaat agtaataatc
     7441 ataaaataat tatatcatag cgatagctat ttctggaaca gaaaatctga aatgttgttt
     7501 ttttcacatg aagtgtacct gttttcaaaa agcactttat tctatcgttg cttaactatg
     7561 aactttgcaa tattcttctc aaaaacttgt aggacatctt caaaattttg caaggagtga
     7621 ttagacttgt tcggtaacca taaagtgtca tactatgtta tgtatgaaaa agcaatgcaa
     7681 ctaactcctg agaactttaa attactaatt ggtgccgaaa aggtagaatt tagaatcgag
     7741 gtacacctat ggctgtaaaa tttacaaaat gagacaactt gggcaagatg tttgaagaat
     7801 ttcctaaact ccctgatttg aagcaagtca ctttccctga tgacaaagaa aaaagccaaa
     7861 acagcaaaga aaaactagat gactgctttc caacaactcc catctagtgt gcttcagact
     7921 gggctatttt tctctccatc tgttagcttg gattctcaga ccgtttcagc taaagaatat
     7981 cttttccctt atcagaagga acggctcaaa ccattcagac aagtgaaggg acgacaagcc
     8041 aatatttgaa accagatagc agttcttata gtcaattgaa ataaaatctg aagaaatcga
     8101 gtaggaaact catatcaatt tttaacagtg ttctattcca gattcatact caatgaaaat
     8161 taaagtgcaa actaggaagt tagccgcagg ctgtacttga gtacggcaag gtgaaactga
     8221 cgtggtttga atttgatttt cgaagagtat caatccacta tacatattaa aaagtatgga
     8281 tatcaaaaca aaaaaacagg ctctccgaaa actcggaaag ccttatttta agctgtttct
     8341 agcttcctca cctttacatt tcaaggttcg ggataaaagg ttcaatggac ctttttattt
     8401 agcgattggg taaacagaaa cttgtttttt atcgcgtcct ttacgttcaa agcgtactac
     8461 gccttcaact ttagcgaaca aagtatcgtc tccaccacga ccaacgttta cacctggata
     8521 gatgtgtgta ccacgttgac ggtaaaggat tgatccacct gttacagttt gtccgtcagc
     8581 tgctttagct ccaagacgtt ttgcttgtga atcacgtccg tttgatgtag aacctccacc
     8641 ttttttgtgg gcgaaaagtt gcaagttgtt aagagtcatt tttaacataa tgttttcctc
     8701 cgtgttagtt ttctgtgata actctggttt ggacgaactc agaatagttc tccgataagt
     8761 ttgccatacc taagaaaaat gattcaaaga ataactgggt catttctctc tggtgtgaag
     8821 gaagatcttt tggtatttca accatcagat agccaccttc atcttcgttt aattctagga
     8881 ttggttcata gcctgcaaat ttctcaatag aattgataaa gttaatggca agcgtagaaa
     8941 ccgatgcaca cacgacatct aagccgtatt cgccactctc ggcgtgtcca gtaatttccg
     9001 cacccctcag ctcgccatct tcggctctct caaagactgc ttgtatcatg tgttctcctt
     9061 aaaattaagc gttaattgcg ttgatgacaa cttttgtata tggttgacgg tgaccttgtt
     9121 tacggtggct acctttttta ggtttgtact tgtaagtaac aactttcttt tgttttcctt
     9181 gtttttcaac agttccaact acagtagctc cagcaacaag tggagttccg acaacagtgt
     9241 tttcaccacc aacaagaaca acttcgttaa aagtaacttc ttgaccagct tcaacgttca
     9301 atttttcaat gtaaactgct tgaccaactt caactttaac ttgttttccg ccagttttga
     9361 taattgcgta tgtgctcatt atgcacctcc tatgattttt atgggtttcc ccgatttttt
     9421 gtgaagactc gcctagcatc gtgggacaaa ccacttaaac ttgaataatc aagcaacgat
     9481 gttcgtgcgg ttgcacagga tcgtgcatag tcaactcttc aagtatagca tatctcctat
     9541 tttcttacaa gtaataacac ctaaaatcaa gctttttctt ttactttttt ctgccactag
     9601 gcaaaaagca tactgagata aaaaatgctc atcataatag gaacaccaag aatggtcttt
     9661 tcatgataga aaatcgtcaa ataggctgaa aagacatcgc caaggacaaa actactaagc
     9721 aggctaacaa atatgaaccc ttcacgcaaa aaaggagtgt gcttagttcg gaaataatct
     9781 ccaaaagcta gcattgttcg tttgatattc cctgtcataa aggcattatt gtaggcaata
     9841 cccgaaacct caccaaaagc agttgtcacc agtcccatac agaaggccaa gggctgcact
     9901 agatagatat tatctacagt ttgtggcaca aaaccaataa ttattgatag gattgctaaa
     9961 ggaatcaagg acagaatagg ttttttcaca attctcaatt tttccttata aatcgttaat
    10021 aaaaagactc ccattataaa cgttattaag gttaaaagct tatccctaac atccgaaaca
    10081 ttattttgta ttagctctac cgaaagaaag acaacatttc cagcttgtcc agctacaagg
    10141 gtattccctc gaacaataaa agtgtaagca tccacatatc cagcacaaaa tgtcaaaaaa
    10201 gtgctaacct tttagactga cgtgatattt ttcttatagg taataacctc attttccctc
    10261 ccattgtatt ttctcttaga aatattgtac catttctttc taaaaaatcg tagactacca
    10321 tttagatttt actattagca taaaaataat aatagacaac tatttatcca aaaatagata
    10381 gaggtaacat gtttgcaaac aaagcatacg aacctttagt aaaatcattt ccatgaaact
    10441 agaatagagc ccctcttagc aaaaatcatt attttaattt atttctaatc actccttgac
    10501 ataaataact ctcaccaata aaagactatg tcttaaaaaa atggtataat aaaatcaata
    10561 cctgggcttg atggctatgc tactaataac aattaggaga gaaaatcagg cacttgttaa
    10621 caacaaggat tatccccttg agatgaaagg aactttagaa atcttatgat gaacatgcaa
    10681 aacatgatgc gtcaagcaca aaaacttcaa aaacaaatgg aacaaagcca agctgaactt
    10741 gctgctatgc aatttgttgg caaatctgct caagatcttg tccaagcgac cttaactggc
    10801 gataagaaag ttgtcagcat tgatttcaat ccagctgtcg ttgacccaga ggaccttgag
    10861 actctttctg atatgaccgt tcaagccatc aactctgctc ttgaacaaat cgatgaaact
    10921 actaagaaaa aactgggtgc tttcgctggg aaattgccat tctaaaaaca aggagctaga
    10981 acaatacttg tcgataacaa aggctaagaa aggtgcaaaa attataaaaa acgcatagta
    11041 tcaagcaacc taaaactttg ggctctataa tatttgtagt gggtaaatcc actatagata
    11101 ttatggagcc tattttattg tagaaaaaaa tcccataaga tctataatga aaagcgacca
    11161 aacaactcat tagaaagatt catatgggac aattacattt tatcacaaaa ttactagaca
    11221 ttaaagaccc taatatccag attttagaca tcatcaataa ggatacacac aa
//
LOCUS       DAVBBO010000063        10995 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ST1
            SAMEA2066453-rid20184263.denovo.063, whole genome shotgun sequence.
ACCESSION   DAVBBO010000063 DAVBBO010000000
VERSION     DAVBBO010000063.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2066453
            Sequence Read Archive: ERR351777
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 10995)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10995)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980402.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980402.1
            Genome Coverage       :: 176x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:17:33
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,141
            CDSs (total)                      :: 2,104
            Genes (coding)                    :: 1,953
            CDSs (with protein)               :: 1,953
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 16S)
            partial rRNAs                     :: 1 (23S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 151
            CDSs (without protein)            :: 151
            Pseudo Genes (ambiguous residues) :: 0 of 151
            Pseudo Genes (frameshifted)       :: 73 of 151
            Pseudo Genes (incomplete)         :: 76 of 151
            Pseudo Genes (internal stop)      :: 40 of 151
            Pseudo Genes (multiple problems)  :: 32 of 151
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10995
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2066453-rid20184263.denovo.063"
                     /strain="ST1"
                     /db_xref="taxon:1313"
     gene            1..269
                     /locus_tag="VQU30_001850"
                     /pseudo
     CDS             1..269
                     /locus_tag="VQU30_001850"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611512.1"
                     /note="frameshifted; incomplete; missing N-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(385..1188)
                     /locus_tag="VQU30_001851"
     CDS             complement(385..1188)
                     /locus_tag="VQU30_001851"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fic/DOC family protein"
                     /protein_id="HET2447904.1"
                     /translation="MQSTYNIDNPNLSYEAKRDLWRIGFGLQKVDNLVPSAYMESLAE
                     KQSRGELTYEQVYEDATAYHHTIDASTEEADLVSLRIVELLSRRGFSFSPATLLAIHK
                     ELFQDIFEPSIPVGQFRQTNITKNEPVLNGESVVYSDYSMIQMTLDYDFNQEKQVAYA
                     TLTQADVVKQIQHFISGIWQIHPFREGNTRTVTVFLIQYLREFGFDIDNTPFQQHSKY
                     FRDALVLDNAKILQRRSEFLTAFFENLLLGGQNDLSSEKMYLDLDLDFS"
     gene            complement(1467..2222)
                     /locus_tag="VQU30_001852"
     CDS             complement(1467..2222)
                     /locus_tag="VQU30_001852"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000033780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3883 domain-containing protein"
                     /protein_id="HET2447905.1"
                     /translation="MSKHPHYELLNLIGYGLAKFDKLFIKEFQCSSKSEFYRYVVSLG
                     IAETTGVVKNRMDLFDPYFDNNRKGWWQKAEVYRFRKDLIDMMFGNEDVHSYAEIVKM
                     LLASEGKKTGITIVEKPIVRTKFKRLQETGMEAENYFILHFDKEEKFQGGQLTDARLY
                     GDGYDFQVDVQEYSYLAEVKGIRKSKGRVRLTAKEFEKVKEFQSDFILSLVTNLDDIP
                     KLVLIDNPLKHFEFKKNIIKNEIIEYRSVEDLY"
     gene            complement(2292..4943)
                     /locus_tag="VQU30_001853"
     CDS             complement(2292..4943)
                     /locus_tag="VQU30_001853"
                     /EC_number="6.1.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009732359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="valine--tRNA ligase"
                     /protein_id="HET2447906.1"
                     /translation="MSKELSSKYNPAEVEAGRYQKWLDADVFKPSGDQKAKPYSIVIP
                     PPNVTGKLHLGHAWDTTLQDIIIRQKRMQGFDTLWLPGMDHAGIATQAKVEERLRGEG
                     ISRYDLGRESFLTKVWEWKDEYSTTIKEQWGKMGLSVDYSRERFTLDEGLSKAVRKVF
                     VDLYKKGWIYRGEFIINWDPAARTALSDIEVIHKDVEGAFYHMNYMLEDGSRALEVAT
                     TRPETMFGDVAVAVNPEDPRYKDLIGKNVILPIANKLIPIVGDEHADPKFGTGVVKIT
                     PAHDPNDFLVGQRHNLPQVNVMNDDGTMNELAFEFSGMDRFEARKAVVAKLEEIGALV
                     KIEKRVHSVGHSERTGVVVEPRLSTQWFVKMDQLAKNAIANQDTDDKVEFYPPRFNDT
                     FLQWMENVHDWVISRQLWWGHQIPAWYNEAGEIYVGEEAPAGDGWKQDEDVLDTWFSS
                     ALWPFSTMGWPNTETTDFKRYYPNSTLVTGYDIIPFWVSRMIFQGIEFTGKSPFKNAL
                     IHGLIRDEEGRKMSKSLGNGIDPMDVIDKYGTDSLRWFLSNGSAPGQDVRFSYEKMDA
                     SWNFINKIWNISRYILMNNEGLTLDVAHDNVTKVATGEAGNVTDRWILHNLNETIAKV
                     TENFDKFEFGVAGHILYNFIWEEFANWYVELTKEVLYSDNEEEKVITRSVLLYTLDKI
                     LRLLHPIMPFVTEEIFGQISEGSIVTAEYPTVNPAFEDLAAHTGVESLKDLIRAVRNA
                     RAEVNVAPSKPITILVKTSDSDLEAFFNSNVNYIKRFTNPEHLEIASTIPAPELAMSS
                     VITGAEIFLPLVDLLNVEEELARLEKELAKWQKELDMVGKKLSNERFVANAKPEVVQK
                     ERDKQADYQAKYDATVARIDEMKKLVK"
     gene            complement(4936..5514)
                     /locus_tag="VQU30_001854"
     CDS             complement(4936..5514)
                     /locus_tag="VQU30_001854"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000550018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HET2447907.1"
                     /translation="MHLFIIGAPASGKMTIGQELSRLTDATLFYNHQAIDFALEIYQD
                     YTEEMWEFVRGITFSFLGASARNQRSVILTDVIDFSNQYQLMYLKQIQNLLDDYHQEI
                     LFVELETSLEECIRRNRTENRLKHKPLKRHIEVSEREILETAETLQLNSQYQPNELHH
                     YFKINNTNLSAEEAAKQIQNKINKIEKGHTHV"
     gene            complement(5514..5984)
                     /locus_tag="VQU30_001855"
     CDS             complement(5514..5984)
                     /locus_tag="VQU30_001855"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000124546.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HET2447908.1"
                     /translation="MARTELPDKIETERLVLRVRTVADAEDIFDYASLPEVAYPAGYG
                     IVVKGTDKIVGSVDFNHRHEDDVLEIGYTLHPDYWGRGYVPEAARALIDLAFKDLGLH
                     KIELTCFGYNLQSQRVAEKLGFTLEARIRDRKDAQGNCCDDLRYALLKSEWEVI"
     gene            complement(5971..6549)
                     /locus_tag="VQU30_001856"
     CDS             complement(5971..6549)
                     /locus_tag="VQU30_001856"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008809142.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavin reductase family protein"
                     /protein_id="HET2447909.1"
                     /translation="MKQSFKTNKLYYGFPVFILGYQDQNFGYNITTCSSSYSLGDWVV
                     IGVVARENAAEQIKQYQKFTVNISDETSMLAMEQAGFISHQEKLERLGVHYEISERTQ
                     TPILDACPLVLDCRVDRIVEEDGICHIFAKILERLVAPELLDEKGHFKNQLFAPTYFM
                     GDGYQRVYRYLDKRVDMKGSFIKKARKKDGKN"
     gene            complement(6832..7227)
                     /locus_tag="VQU30_001857"
     CDS             complement(6832..7227)
                     /locus_tag="VQU30_001857"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000038635.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helicase"
                     /protein_id="HET2447910.1"
                     /translation="MSKKLNRKKQLRNGLRRAGAFSSTVTKVVDETKKVVKRAEQSAS
                     AAGKAVSKKVEQAVEATKEQAQKVANSVEDFAANLGGLPLDRAKTFYDEGIKSASDFK
                     NWTEKELLALKGIGPATIKKLKENGIKFK"
     gene            complement(7323..7577)
                     /locus_tag="VQU30_001858"
     CDS             complement(7323..7577)
                     /locus_tag="VQU30_001858"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000119704.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1912 family protein"
                     /protein_id="HET2447911.1"
                     /translation="MSYEQEFMKEFEAWVNTQIMINDMAHKESQKVYEEDQDERAKDA
                     MIRYESRLDAYQFLLGKFENFKVGKGFHDLPEGLFGERNY"
     gene            complement(7586..8920)
                     /locus_tag="VQU30_001859"
     CDS             complement(7586..8920)
                     /locus_tag="VQU30_001859"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000752887.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF438 domain-containing protein"
                     /protein_id="HET2447912.1"
                     /translation="MTDEWIHILRDILLELHNGASPESVQDRFDATFTGVSAIEISLM
                     EHELMNSDSGVTFEDVMELCDVHANLFKNAIKGVEVLDTEHPGHPVRVFKEENLALRA
                     ALIRIRRLLDTYELMEDEEMLAEMRKGLVRQMGLVGQFDIHYQRKEELFFPIMERYGH
                     DSPPKVMWGVDDQIRELFQTALTTVKSLPEVSISSVKEAFEAFATEFESMIFKEESIL
                     LMILLESFTQDDWLQIAEESDAYGYAIIRPSEKWVPERQSFIEEKIAEEPVQLDTAEG
                     QVQQVIDTPEGHFTITFTPKEKEAVLDRHSQQAFGNGYLSVEQANLILNHLPMEITFV
                     NKEDIFQYYNDNTPADEMIFKRTPSQVGRNVELCHPPKYLDKVKTIMKRLREGSKDKY
                     EMWFKSESRGKFVHITYAAVHDEDGEFQGVLEYVQDIQPYREIDTDYFRGLE"
     gene            complement(8920..9153)
                     /locus_tag="VQU30_001860"
     CDS             complement(8920..9153)
                     /locus_tag="VQU30_001860"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006144975.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1858 domain-containing protein"
                     /protein_id="HET2447913.1"
                     /translation="MDNIIDVSIPVAEVVDKHPEVLEILVELGFKPLANPLMRNTVGR
                     KVSLKQGSKLTGTPMDKIVRTLEANGYEVIGLD"
     gene            9184..9258
                     /locus_tag="VQU30_001861"
                     /pseudo
     CDS             9184..9258
                     /locus_tag="VQU30_001861"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001829418.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopyranose mutase"
     gene            9247..9372
                     /locus_tag="VQU30_001862"
     CDS             9247..9372
                     /locus_tag="VQU30_001862"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004238277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lysyl-tRNA synthetase"
                     /protein_id="HET2447914.1"
                     /translation="MDRTDEVSNHTYSKVKLTWFEEIFEEYKMILLLILYHMERD"
     gene            complement(9422..9562)
                     /locus_tag="VQU30_001863"
     CDS             complement(9422..9562)
                     /locus_tag="VQU30_001863"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000668195.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2447915.1"
                     /translation="MKFFWTILAILFIKPIIGIVKFFWMIISFAVQLLFYKILDWFFK
                     LI"
     gene            complement(9559..9741)
                     /locus_tag="VQU30_001864"
     CDS             complement(9559..9741)
                     /locus_tag="VQU30_001864"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001068155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2447916.1"
                     /translation="MNPIKAFAKIYGNYFLTVQGVKVMKTIKKDDHVVVGLGKLFIAD
                     KLMDTARWLIKPEERE"
     gene            complement(9743..10526)
                     /locus_tag="VQU30_001865"
                     /pseudo
     CDS             complement(9743..10526)
                     /locus_tag="VQU30_001865"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000840413.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
BASE COUNT         3226 a         2419 c         2023 g         3327 t
ORIGIN      
        1 cgacacgatt cttatcatcg gttcctaaga gtaagggaat tcaagcatct atgtcacgca
       61 agggaaacag ccaagacaac ggtatgatgg agtccttctt tgggattctg aaatcggaaa
      121 tgttttacgg ttatgagaag tcgtttcagt cgcttaagca attggaacaa gccattatag
      181 actatattga ttactacaac aataaacgaa ttaaggtaaa actaaaagga cttagccttg
      241 tgcaatacag aactaaatcc ttcggataaa ttatttgtct aactttttgg ggtcagtaca
      301 cctaaaactt tgatgatata cgttttcttg tgagaatatt tacttcattt ttgcctaaaa
      361 ttcaatgttt actcagtatt tggattatga aaaatcgagg tctaaatcta gatacatttt
      421 ttctgaagac aaatcatttt gaccaccgag caagagattt tcaaaaaaag ctgttaaaaa
      481 ctcagaacgt cgctgtaaaa tctttgcatt atctaatacc aaggcatcac gaaaatattt
      541 ggaatgttgc tgaaatggtg tattatcaat atcaaaacca aactcacgaa gatactgaat
      601 caaaaagacc gttactgtcc gagtgtttcc ttcgcgaaat ggatgaatct gccagattcc
      661 tgaaataaaa tgctggattt gtttaaccac atccgcctga gttagtgtcg catatgcaac
      721 ttgtttttcc tgattaaaat cataatctaa ggtcatttga atcatggagt aatcagagta
      781 cacaacactt tcaccattca aaacaggttc attctttgtg atattggtct gacgaaattg
      841 ccccaccgga atagagggtt caaatatatc ttgaaacaac tccttatgaa tagcaagtaa
      901 ggtcgcagga ctaaagctaa agcctcttcg agacaatagt tctacaatac gtagagaaac
      961 caagtctgcc tcttccgtac ttgcatcaat agtatggtga taagccgttg catcctcata
     1021 aacctgctca taagtcagtt ctccccggga ctgtttctca gccaaagatt ccatatacgc
     1081 tgatggcact agattgtcaa ctttctgcag accaaaacct atccgccata aatcacgctt
     1141 cgcttcataa gacaagtttg gattgtcaat gttgtaagtt gattgcatag aaatatcctt
     1201 tcaattgttt ttcttcatta ccagtaaatc acgaaattgg ttggaaactg gcttaaacta
     1261 taaaaagtcc tcacaatagg ttctatgata tatatatata tacttcatgt aaataataaa
     1321 agagttataa tcagcactac tgataaattc aataccgatt tcgccatctt aaaacttagt
     1381 caaacgaata ccgttgattt ccagttcatt aagtcgttga cctgtcaaga cttctcgttc
     1441 cttcaactgg aaaagttaag ggggaactaa tacaaatcct ctacgcttct atattcaatg
     1501 atttcatttt tgataatatt ctttttaaac tcaaaatgtt ttaaaggatt atcgattaac
     1561 actaactttg gaatatcatc tagatttgtg accaaggata aaataaaatc cgattgaaac
     1621 tccttgactt tttcaaattc ttttgcagtt aaacgcacac gccccttaga ttttcggata
     1681 ccttttactt cggcaaggta agaatactct tggacatcta cctgaaagtc atatccatca
     1741 ccataaagac gggcatcggt taactgtcca ccttggaatt tttcttcttt atcaaaatga
     1801 aggataaaat aattctcagc ctccattccc gtttcctgta gacgtttgaa tttagttcga
     1861 actattggtt tttcaacgat ggttatgcct gttttcttcc cttcactggc aagtaacatt
     1921 ttaactattt cagcataact atgaacatct tcatttccaa acatcatatc aattaaatct
     1981 ttacgaaaac gataaacttc agctttctgc caccaacctt ttcgattatt gtcaaaataa
     2041 ggatcaaata aatccattct attttttaca actccagttg tttcagcaat tcccagagaa
     2101 accacatagc gataaaactc cgacttgcta gagcattgaa attcttttat aaaaagcttg
     2161 tcaaacttgg caagaccgta gccaattaaa tttaacaatt cataatgagg gtgtttggac
     2221 atcactttct ccatcaatag atattgattt cattatacca aaaaacacgg ctcatcaccg
     2281 tgtttctgtg tttatttcac caacttcttc atctcatcaa tacgtgctac ggtcgcatca
     2341 tacttagctt ggtaatctgc ttgcttgtcg cgttcttttt ggacaacttc tggtttagcg
     2401 ttggcgacga agcgttcgtt gctgagtttt ttgccaacca tgtcgagttc tttctgccat
     2461 ttggcaagtt ctttttccag acgtgccaat tcttcttcga cattcaagag gtctaccagt
     2521 ggcaagaaga tttcggctcc tgtgatgacg cttgacatag ccagttcagg tgcagggatg
     2581 gttgatgcga tttccaagtg ttcaggattt gtgaaacgtt tgatgtagtt gacattgctg
     2641 ttaaagaagg cttccaagtc gctatcgctt gtcttaacaa ggatagtgat aggcttgctt
     2701 ggagcaacgt ttacttccgc acgcgcatta cgaacggcac ggatcaagtc tttaaggctt
     2761 tccacaccag tgtgagcagc aaggtcttca aaggctgggt tgacagttgg gtattctgct
     2821 gtaacgatag atccttctga gatttgtcca aagatttcct ctgtcacaaa tggcatgatt
     2881 gggtgaagga gacgaaggat cttgtccaaa gtgtatagta gaacagaacg tgtgatgact
     2941 ttctcttctt cgttatcgct ataaaggact tccttggtca actcaacata ccagttggca
     3001 aattcttccc agatgaagtt gtaaaggata tgaccagcca caccaaactc gaacttatca
     3061 aagttttcag taacttttgc aatggtttcg ttgagattgt ggagaatcca gcggtccgtc
     3121 acattaccag cctcacctgt tgcaactttt gtgacattgt catgcgccac atccagcgtc
     3181 aaaccttcat tgttcatgag gatatagcga gaaatgttcc aaattttgtt aataaagttc
     3241 catgaagcat ccattttctc gtaagagaaa cgaacgtctt gaccaggagc tgagccgttt
     3301 gacaagaacc aacgaagact atctgtacca tatttatcaa taacatccat tgggtcaatg
     3361 ccatttccaa gagatttaga catcttacgt ccttcttcat cacgaattag accatggata
     3421 agagcatttt taaatgggct ctttcctgta aattcaattc cttggaaaat catgcgtgat
     3481 acccagaaag gaataatatc atagcctgtt acgagtgttg aatttggata gtagcgttta
     3541 aagtcagtag tttcggtatt aggccagccc atggttgaga agggccagag ggcagagctg
     3601 aaccaagtgt caaggacatc ttcgtcctgt ttccagccat cgcccgctgg ggcttcctcg
     3661 ccgacataga tttcgcctgc ttcattatac caagcaggga tttggtgacc ccaccagagc
     3721 tgacgggaaa tcacccagtc gtggacattt tccatccatt gcaggaaggt gtcgttgaag
     3781 cgcggtgggt aaaattccac cttgtcatct gtgtcttggt tggcaatggc gttcttggcc
     3841 aattggtcca tcttgacgaa ccattgagta gacaagcgtg gctcaactac gacacctgtc
     3901 cgttctgagt gaccgactga atggacacgt ttttcgattt tgacaagggc accgatttct
     3961 tccaacttag caacgactgc cttacgagct tcaaaacgat ccatgcctga aaattcaaag
     4021 gcaagctcgt tcatagttcc gtcgtcgttc atgacgttga cttgtggcaa gttatgacgt
     4081 tggccaacca agaagtcatt tggatcgtgg gcaggtgtga ttttcacgac accagtacca
     4141 aacttaggat ctgcgtgctc atcaccaacg attgggatta atttattagc aattggaagg
     4201 atgacatttt taccaatcaa gtccttgtag cgcgggtctt ctgggttgac cgcaaccgca
     4261 acgtccccaa acatggtctc aggacgagtt gtagcaactt caagggcgcg tgaaccatct
     4321 tccagcatgt aattcatgtg atagaaggca ccttcgacgt ccttgtgaat aacctcgata
     4381 tcagaaaggg ctgtgcgagc tgctgggtcc cagttgatga taaactcacc acggtagatc
     4441 cagcctttct tgtaaaggtc cacaaagacc ttacgaacag cttttgacaa accttcgtca
     4501 agagtgaaac gctcacgaga gtagtctaca gagagcccca tcttgcccca ttgttccttg
     4561 atagtagtgg aatattcgtc tttccattcc cagactttcg tcaagaaaga ctcacgacca
     4621 aggtcatagc gggaaatgcc ctcaccacgc aagcgctcct ctaccttagc ctgagtggca
     4681 atccctgcgt ggtccatccc aggaagccaa agggtatcaa aaccttgcat gcgtttttga
     4741 cggatgataa tatcttgcaa agttgtatcc caagcgtgac caaggtgaag tttacctgta
     4801 acgtttggtg gtggaataac gattgaataa ggcttagcct tttgatcgcc tgaaggcttg
     4861 aaaacatcag catcaagcca tttttggtaa cgaccagcct caacctcggc tggattgtat
     4921 ttagatgaaa gttctttaga catgtgtgtg tcctttctct attttgttta ttttattttg
     4981 aatttgctta gcagcttctt ctgcagacaa attcgtatta tttattttaa agtagtggtg
     5041 caactcattc ggttgatatt gggaatttaa ttgaagtgtt tcagcggtct ctaaaatttc
     5101 tctttcagat acctcaatat gtcgttttaa gggtttgtgc tttaatcgat tctccgttcg
     5161 atttcgacgt atgcactctt caagacttgt ttccaactca acaaaaagaa tctcttgatg
     5221 ataatcatcc aacaaattct gaatttgctt taaatacatc agttgatact gatttgaaaa
     5281 atcaattaca tctgttaaaa ttactgatcg ctgatttctt gcacttgctc caaggaatga
     5341 aaaagtgatt ccacgaacaa attcccacat ttcctctgta tagtcctgat agatttctag
     5401 tgcaaaatca atggcttgat ggttataaaa tagggtagca tccgtcagtc gagataattc
     5461 ttgaccaatg gtcatttttc ctgatgctgg agcaccaatg atgaaaagat gcatcaaatc
     5521 acctcccact cactcttcag caaggcatat ctcaaatcat cacagcagtt gccttgagca
     5581 tctttacggt ctcttatgcg agcttcgagg gtaaagccaa gcttttccgc gactcgttga
     5641 ctttgaaggt tatatccaaa gcaagttagt tcaatcttgt gaagacccaa atctttaaag
     5701 gctaagtcaa tcaaggcacg cgcagcttct ggcacataac ctcgccccca atagtctggg
     5761 tgtaaggtat agccgatttc cagcacatca tcttcatggc gatggttgaa atcgacagag
     5821 ccaacgatct tatccgttcc tttgacgaca atcccgtagc ctgctggata ggcgacctct
     5881 ggcaaactag catagtcaaa gatatcctca gcatccgcca cagtacggac tcgtaaaacg
     5941 agacgttctg tttcgatttt atctggcagc tcagttcttg ccatccttct tcctcgcttt
     6001 tttgatgaaa ctgcccttca tatctacacg cttatccaga tagcgataaa cgcgctgata
     6061 tccatctccc atgaaatagg ttggggcaaa cagttgattt ttaaaatgtc ccttttcatc
     6121 caggagttct ggggcaacaa gtcgctcaag aatcttggca aagatgtggc aaataccgtc
     6181 ttcctcaaca atcctatcta cccgacaatc taaaacaagt ggacaggcgt ctaaaatagg
     6241 agtctgagtt cgttcagaaa tttcataatg cactcccaaa cgttccaatt tctcctgatg
     6301 actgataaaa ccagcctgct ccatcgcaag catagaagtt tcatcagaaa tattcacagt
     6361 aaatttttga tactgtttga tctgctctgc ggcattctct ctcgcaacga ctccaatcac
     6421 aacccaatct cctagactat acgaggaact acaggtcgtg atgttatagc caaaattctg
     6481 atcttgatat cctaaaataa aaacaggaaa accataatat agtttattag ttttaaatga
     6541 ttgttttata acaacctcct ttgactaaga cacaaaagaa aagccctgcc atctacatga
     6601 cagggacgaa tgtatttatc cgcggtacca cccaatttcg ggccaagccc gcatctttag
     6661 tctttaaaat aaaaagacag aaatatttca ttttttcagt cattagcaac cagttttgac
     6721 acatttgtgg acttctcagc gccgccactt tctgtaaaat gtgggattca aaacacctct
     6781 aatagctcta ttgtagcaag tttttctcgg aaatgcaagg ctcaagaaaa attacttgaa
     6841 cttgatgcca ttttctttca atttcttgat ggtagctggg ccgattcctt tcaaggcaag
     6901 gagttctttt tcagtccagt ttttgaaatc tgaagcagac ttgattcctt catcatagaa
     6961 agtcttggca cgatcaagtg gaagtccacc caagtttgct gcaaaatctt ctacagaatt
     7021 agctactttt tgagcttgct ctttggtagc ttctactgct tgttcaactt ttttagaaac
     7081 agccttacca gctgcgcttg ctgactgttc tgcacgcttc acgacttttt ttgtctcatc
     7141 tacaacctta gtcacagtac ttgaaaaggc acctgcgcga cggaggccat ttcgtaattg
     7201 ttttttacga ttgagtttct ttgacatgat aaaatccttt caataaaaaa tccctgctct
     7261 gacaaggatt taacataaac attctatcaa gattttagtg aaaaatcaag aatctttctc
     7321 gtttaataat ttcgctcacc aaacaagcct tctggcaaat catggaatcc cttgcctact
     7381 ttgaagtttt caaacttacc aagcaagaac tgataagcat ccaagcgact ctcgtagcga
     7441 atcatggcat ctttggcacg ctcgtcctgg tcttcttcgt aaactttttg actttccttg
     7501 tgcgccatgt cgttaatcat gatttgggta ttgacccaag cttcaaattc cttcataaat
     7561 tcttgttcgt aactcatttt tctccttatt ctaatccacg aaaatagtcc gtatcaatct
     7621 cacggtaggg ctggatatcc tgaacatact ccaacactcc ttggaattct ccgtcttcat
     7681 cgtgtactgc agcataggtg atgtggacaa acttacctcg cgactcagac ttgaaccaca
     7741 tttcatactt gtctttgctt ccctcacgaa gcctcttcat gatagttttg accttgtcca
     7801 agtacttagg cggatggcag agttcgacat tgcgcccgac ttgagacggc gtccgtttga
     7861 aaatcatctc atcagctggc gtattgtcat tgtaatactg gaaaatatct tctttattga
     7921 caaaggtaat ctccataggg agatgattga ggatgagatt ggcctgctcg actgaaagat
     7981 agccattacc aaaagcctgt tgactatggc ggtccagcac agcttccttt tccttagggg
     8041 taaaggtaat ggtaaaatgg ccttctggcg tatctatgac ttgttgaact tgaccttctg
     8101 ccgtatctag ctgtacaggc tcctctgcaa tcttttcctc aataaagctc tgtcgttctg
     8161 gcacccattt ctctgacgga cggatgatgg catagccata ggcatcgctc tcctccgcaa
     8221 tctgaagcca gtcatcctga gtaaaagact caaggagaat catgaggagg atggactctt
     8281 ccttgaaaat catactttca aactctgtcg caaaagcttc aaaagcttcc tttacactgc
     8341 taattgacac ttctggtagt gacttgactg tcgttagagc tgtttgaaag agttccctaa
     8401 tctgatcatc cactccccac ataactttgg gaggtgaatc gtgtccatag cgctccatga
     8461 taggaaagaa gagttcttcc ttacgttggt aatggatgtc aaattgcccc acaagcccca
     8521 tctgacgcac caagcccttg cgcatctccg caagcatttc ctcgtcttcc atcaactcat
     8581 aggtatctaa caatctacga atgcgaatca aagctgcacg gagggccaaa ttttcttcct
     8641 taaagacacg aactgggtgc ccagggtgtt cggtatctaa aacttcgaca cctttgatag
     8701 catttttaaa aagattggca tggacatcac agagttccat aacatcttca aaagtgacgc
     8761 ccgaatccga gttcatcagc tcgtgctcca taagggaaat ctcgatggct gacacgcccg
     8821 taaaggtcgc atcaaagcga tcttgaaccg actcaggaga ggcgccattg tgcaattcta
     8881 acaaaatatc ccgtaggata tgaatccatt catctgtcat tagtctaatc caatcacttc
     8941 gtagccattc gcttccagtg tgcgtacaat cttgtccata ggagttcctg ttagcttaga
     9001 accctgttta agtgatactt tacgaccaac tgtattgcgc attaagggat tggcaagggg
     9061 tttaaaaccc aactccacta gaatttccaa gacttctgga tgcttgtcca ccacttctgc
     9121 aacaggaatt gacacatcga tgatattgtc catgacgacc tccattgtat gttctaatac
     9181 tcaatgaaaa tcaaagagca aactaggaag ctagccgcag gttgctcaaa acagtgtttt
     9241 gaggttgtgg atagaactga cgaagtcagt aaccatacct acagcaaggt gaagctgacg
     9301 tggtttgaag agattttcga agagtataaa atgattttac tgcttatatt ataccatatg
     9361 gagagagatt aaaaaactag cagtggagtt cctgctagtt ttctgcgact tggattacca
     9421 tctagataag tttaaagaac caatccaata tcttgtaaaa cagcaattga actgcaaaag
     9481 aaatgatcat ccaaaagaat ttcacaatcc caataatcgg tttgataaaa agaatagcaa
     9541 gaattgtcca gaaaaatttc attctctctc ctctggctta atgagccacc gagccgtatc
     9601 cattagctta tctgcaataa agagttttcc cagaccaaca acgacatggt catctttctt
     9661 tatcgttttc atcactttta caccttgcac ggtcaaaaag taattaccat aaattttagc
     9721 aaaagctttg ataggattca tattattctc ctttgatgat ttcagcctct tttcggattg
     9781 tttcaacatc ttcttgatat tgaacttcac tatagttgac tagcttggat aattctttct
     9841 gcaagctttc ccccattggt ttcatagttg caaaggttaa accacctgaa atgataccac
     9901 ccaagatagg aataaatttc cccattcctt tggccaaccc tcccttggta agattcacac
     9961 caaatatttt taagactttt ttcaaaatag ggtaccaaag cgtctttgtt aaagctttat
    10021 taggcactgt tttcattacc tgtttggcaa ttgttatacc accagcacgt agcaaacaaa
    10081 gcagcggttc cattcacccc taacattacg cctagataaa gcaagagggt attttgagca
    10141 tcttcactca actcctcacg tgaagcccaa agatcctcat aaccataaat ataacctaat
    10201 tcttgggcca atttcagaga gaaaccataa aattgagcca cataagctgg aatggtaatt
    10261 gccatagcaa gccctccagg taatcctgcc aaaacagaag tcccactcgc taataaaaca
    10321 ttatccctaa tacaggcatt agccactcga tctaagattt cttgagataa gagagacgtt
    10381 ggaccttgtt ccaataaggt aggaatgtcc tgtggaccca attctttgga aaacttatcc
    10441 actaaaaatt tcgaacgatc aaccttaaca actggtagtt ttaccacttg ttgtaatact
    10501 tgcatagcta agtcttgttc agccatatac aaactcctta tttctttttt gcaccttatc
    10561 atattatatt tcctacaaaa aaagcatttt ctaattagat aacattaaaa aatacagaac
    10621 ccctttttta tagtaaaata aaacaagaac aggacaaatc gatcaggaca gtcaaatcga
    10681 tttctaacaa tgttttagaa gtagaggcgt actattctag tttcaatata ttttaaaaga
    10741 atatttttcc atttcaaatt caacctattt tcctccacca aaaaagggct ctataatatt
    10801 tgtagtgggt aaattcccta tggatattat ggagcctatt tttgtgtaga aaaaaagtcc
    10861 catatgacct ataatgaaaa gcgacaaaac aactcattag aaagaatcat atggaacaat
    10921 tacattttat cacaaaactg ctcgatatta aagacccaaa catcaagatt ctagatatca
    10981 tcaataaaga tacac
//
LOCUS       DAVBBO010000064        10989 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ST1
            SAMEA2066453-rid20184263.denovo.064, whole genome shotgun sequence.
ACCESSION   DAVBBO010000064 DAVBBO010000000
VERSION     DAVBBO010000064.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2066453
            Sequence Read Archive: ERR351777
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 10989)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10989)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980402.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980402.1
            Genome Coverage       :: 176x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:17:33
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,141
            CDSs (total)                      :: 2,104
            Genes (coding)                    :: 1,953
            CDSs (with protein)               :: 1,953
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 16S)
            partial rRNAs                     :: 1 (23S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 151
            CDSs (without protein)            :: 151
            Pseudo Genes (ambiguous residues) :: 0 of 151
            Pseudo Genes (frameshifted)       :: 73 of 151
            Pseudo Genes (incomplete)         :: 76 of 151
            Pseudo Genes (internal stop)      :: 40 of 151
            Pseudo Genes (multiple problems)  :: 32 of 151
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10989
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2066453-rid20184263.denovo.064"
                     /strain="ST1"
                     /db_xref="taxon:1313"
     gene            136..2316
                     /locus_tag="VQU30_001866"
     CDS             136..2316
                     /locus_tag="VQU30_001866"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000974069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HET2447917.1"
                     /translation="MMKDTFKNVLSFEFWQKFGKALMVVIAVMPAAGLMISIGKSIVM
                     INPTFTPLVITGGILEQIGWGVIGNLHILFALAIGGSWAKERAGGAFAAGLAFILINR
                     ITGTIFGVSGDMLKNPDAMVTTFFGGSIKVADYFISVLEAPALNMGVFVGIISGFVGA
                     TAYNKYYNFRKLPDALSFFNGKRFVPFVVILRSAIAAILLAAFWPVVQTGINNFGIWI
                     ANSQETAPILAPFLYGTLERLLLPFGLHHMLTIPMNYTALGGTYDILTGAAKGTQVFG
                     QDPLWLAWVTDLVNLKGTDTSQYQHLLDTVHPARFKVGQMIGSFGILMGVIVAIYRNV
                     DADKKHKYKGMMIATALATFLTGVTEPIEYMFMFIATPMYLVYSLVQGAAFAMADVVN
                     LRMHSFGSIEFLTRTPIAISAGIGMDIVNFVWVTVLFAVIMYFIANFMIQKFNYATPG
                     RNGNYETAEGSEETSSEVKVAAGSQAVNIINLLGGRVNIVDVDACMTRLRVTVKDADK
                     VGNAEQWKAEGAMGLVMKGQGVQAIYGPKADILKSDIQDILDSGEIIPETLPSQMTEA
                     QQNTVHFKNLTEEVYSVADGQVVGLEQVKDPVFAQKMMGDGFAVEPANGNIVSPVSGT
                     VSSIFPTKHAFGIVTEAGLEVLVHIGLDTVSLEGKPFTVHVAEGQKVAAGDLLVTADL
                     DAIRAAGRETSTVVVFTNGDAIKSVKLEKTGSLAAKTAVAKVEL"
     gene            2368..3183
                     /locus_tag="VQU30_001867"
     CDS             2368..3183
                     /locus_tag="VQU30_001867"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398916.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease/exonuclease/phosphatase family
                     protein"
                     /protein_id="HET2447918.1"
                     /translation="MKFLTLNTHSWMEKEAEEKFQILLEDILEKDYDLICFQEINQEM
                     TSSEVEVNDLYQALPAAEPIHQDHYVRLLVEKLLEQGKNYYWTWAYNHIGYDRYHEGV
                     AILSKTPIEAREILVSDVDDPTDYHTRRVALAETLVDGKELAVASVHLSWWDKGFQEE
                     WARFEAVLKKLNKPLLLAGDFNNPAGQEGYQAILASPLGLQDAFEVAQEKSGSYTVPP
                     EIDGWKGNTEPLRIDYVFTTKELAVENLHVVFDGNKSPQVSDHYGLNAMLNWK"
     gene            3323..4666
                     /locus_tag="VQU30_001868"
     CDS             3323..4666
                     /locus_tag="VQU30_001868"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HET2447919.1"
                     /translation="MSFTKFQFKNYIREALKELKFTTPTEVQDKLIPIVLAGRDLVGE
                     SKTGSGKTHTFLLPIFQQLDEASDSVQAVITAPSRELATQIYQVARQISAHSDVEVRV
                     VNYVGGTDKARQIEKLASNQPHIVIGTPGRIYDLVKSGDLAIHKAKTFVVDEADMTLD
                     MGFLEIVDKIAGSLPKDLQFMVFSATIPQKLQPFLKKYLSNPVMEKIKTKTVISDTID
                     NWLISTKGHDKNAQIYQLTQLMQPYLAMIFVNTKTRADELHSYLTAQGLKVAKIHGDI
                     APRERKRIMNQVQNLDFEYIVATDLAARGIDIEGVSHVINDAIPQDLSFFVHRVGRTG
                     RNGLPGTAITLYQPSDDSDIRELEKLGIKFSPKMVKDGEFQDTYDRDRRANREKKQDK
                     LDIEMIGLVKKKKKKVKPGYKKKIQWAVDEKRRKTKRAENRARGRAERKAKRQTF"
     gene            5043..6233
                     /locus_tag="VQU30_001869"
     CDS             5043..6233
                     /locus_tag="VQU30_001869"
                     /EC_number="2.5.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000003937.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionine adenosyltransferase"
                     /protein_id="HET2447920.1"
                     /translation="MSERKLFTSESVSEGHPDKIADQISDAILDAILAKDPEAHVAAE
                     TAVYTGSVHVFGEISTNAYVDINRVVRDTIAEIGYTNTEYGFSAETVGVHPSLVEQSP
                     DIAQGVNEALEVRGNADQDPLDLIGAGDQGLMFGFAVDETEELMPLPIALSHKLVRRL
                     AELRKSGEISYLRPDAKSQVTVEYDENDRPVRVDTVVISTQHDPEATNEQIHQDVIDK
                     VIKEVIPSSYLDDKTKFFINPTGRFVIGGPQGDSGLTGRKIIVDTYGGYSRHGGGAFS
                     GKDATKVDRSASYAARYIAKNIVAAGLAKKAEVQLAYAIGVAQPVSVRIDTFGTGTVA
                     ESQLEKAARQIFDLRPAGIIQMLDLKRPIYRQTSAYGHMGRTDIDLPWERLDKVDALK
                     EAVK"
     gene            6786..7721
                     /locus_tag="VQU30_001870"
     CDS             6786..7721
                     /locus_tag="VQU30_001870"
                     /EC_number="1.3.98.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519812.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotate oxidase"
                     /protein_id="HET2447921.1"
                     /translation="MVSTKTQIAGFEFDNCLMNAAGVACMTIEELEEVKNSAAGTFVT
                     KTATLDFRQGNPEPRYQDVPLGSINSMGLPNNGLDYYLDYLLDLQEKESNRTFFLSLV
                     GMSPEETHTILKKVQESDFRGLTELNLSCPNVPGKPQIAYDFETTDRILAEVFAYFTK
                     PLGIKLPPYFDIVHFDQAAAIFNKYPLKFVNCVNSIGNGLYIEDESVVIRPKNGFGGI
                     GGEYIKPTALANVHAFYQRLNPQIQIIGTGGVLTGRDAFEHILCGASMVQVGTTLHKE
                     GVSAFDRITNELKAIMVEKGYESLEDFRGKLRYID"
     gene            7755..8792
                     /locus_tag="VQU30_001871"
     CDS             7755..8792
                     /locus_tag="VQU30_001871"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001845438.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit delta"
                     /protein_id="HET2447922.1"
                     /translation="MLAIEESQKLTLSNLPSLSLFTGTDQGQFEVMKSQVLKQIGYDS
                     ADLNFAYFDMKEVVYKDVELELVSLPFFADEKIVILDYFMDITTAKKRFLTDDELKSF
                     EEYLDNSSPTTKLIIFAEGKLDSKRRLVKLLKRDAKVFDAVEVKEQELRQYFQKWSQK
                     QGLQFTNHSFENLLIKSGFQFSEIQKNLLFLQSYKANSVIEEEDIVNAIPKTLQDNIF
                     DLTQFILTKKMDQARDLVRDLTLQGEDEIKLIAVMLGQFRTFTQVKILAESGQTESQI
                     ASSLGSYLGRNPNPYQIKFALRDSRGLSLSFLKQAISYLIETDYQIKTGLYEKGFLFE
                     KALLQIASQVN"
     gene            8965..9570
                     /locus_tag="VQU30_001872"
     CDS             8965..9570
                     /locus_tag="VQU30_001872"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519814.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="superoxide dismutase"
                     /protein_id="HET2447923.1"
                     /translation="MAIILPELPYAYDALEPYIDAETMHLHHDKHHQTYVNNANAALE
                     KHPEIGEDLEALLADVESIPADIRQALINNGGGHLNHALFWELMTPEKTAPSAELAAA
                     IDATFGSFEEFQAAFTAAATTRFGSGWAWLVVNKEGKLEVTSTANQDTPISEGKKPIL
                     GLDVWEHAYYVKYRNVRPDYIKAFFSVINWNKVDELYAAAK"
     gene            9726..10256
                     /locus_tag="VQU30_001873"
     CDS             9726..10256
                     /locus_tag="VQU30_001873"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007522225.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YutD family protein"
                     /protein_id="HET2447924.1"
                     /translation="MRKEIAPELYNYNKFPGPEFHLHGDKVETEGIAFSLVENIKDAF
                     DVTTFNQRFSEVLTKFDYIVGDWSNEQLRLRGFYKDDRTEEKLEKISRLQDYLLEYCS
                     YGCAYFVLENEAPKRASFDKKMRKTEEETPSRKGKKPTQTKRKSNADKKNRRRQKDQH
                     SQKEDKEQRHFVIRQK"
     gene            10277..>10989
                     /gene="rlmN"
                     /locus_tag="VQU30_001874"
     CDS             10277..>10989
                     /gene="rlmN"
                     /locus_tag="VQU30_001874"
                     /EC_number="2.1.1.192"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000804770.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (adenine(2503)-C(2))-methyltransferase
                     RlmN"
                     /protein_id="HET2447925.1"
                     /translation="MKPSIHSLAHQTMQEWVLEQGEKKFRADQIWEWLYRKRVQSFEE
                     MTNLSKDLIAKLNDQFVVNPLKQGIVQESADGTVKYLFELPDGMLIETVLMCQHYGLS
                     VCVTTQVGCNIGCTFCASGLIKKQRDLNNGEIVAQIMLVQKYFDERGQDERISHIVVM
                     GIGEPFDNYNNVLNFFRTINDDKGMAIGARHITVSISGLAHKIRDFADEGVQVNLAVS
                     LHAPNNELRSSIMKINRAFP"
BASE COUNT         3341 a         2017 c         2395 g         3236 t
ORIGIN      
        1 tagaaatttt ttagaaaaaa gtgtaatttt tttataaaag cctttacaaa aaaaattaaa
       61 gtggtataat taaatcatag aaggtgcaaa cgttttcgta aaacgtttgc ctaaataaaa
      121 ataaaggaga tttgaatgat gaaagataca ttcaaaaatg tcttgtcttt cgaattttgg
      181 caaaaattcg gtaaggcttt gatggtagtt atcgcggtta tgccggctgc tggtttgatg
      241 atttcaatcg gtaagtctat cgtgatgatt aacccaacct ttacaccact tgtcatcaca
      301 ggtggaattc ttgagcaaat cggttggggg gttatcggta accttcacat tttgtttgcc
      361 ctagccattg gaggaagctg ggctaaagaa cgtgctggtg gtgctttcgc cgctggtctt
      421 gccttcatct tgattaaccg tatcactggt acaatttttg gtgtatcagg cgatatgttg
      481 aaaaatccag atgctatggt aactactttc tttggtggtt caatcaaagt tgctgattac
      541 tttatcagtg ttcttgaagc tccagccttg aacatggggg tattcgtagg gattatctca
      601 ggttttgtag gggcaactgc ttacaacaaa tactacaact tccgtaaact tcctgatgca
      661 ctttcattct tcaacgggaa acgtttcgta ccatttgtag ttattcttcg ttcagcaatc
      721 gctgcaattc tacttgctgc tttctggcca gtagttcaaa caggtatcaa taacttcggt
      781 atctggattg ccaactcaca agaaactgct ccaattcttg caccattctt gtatggtact
      841 ttggaacgtt tgctcttgcc atttggtctt caccacatgt tgactatccc aatgaactac
      901 acagctcttg gtggtactta tgacatttta actggtgcag ctaaaggtac tcaagtattc
      961 ggtcaagacc cactatggct tgcatgggta acagaccttg taaaccttaa aggtactgat
     1021 actagtcaat atcaacactt gttagataca gtacatccag ctcgtttcaa agttggacaa
     1081 atgatcggtt cattcggtat cttgatgggt gtgattgttg ctatctaccg taatgttgat
     1141 gctgacaaga aacataaata caaaggtatg atgattgcaa cagctcttgc aacattcttg
     1201 acaggggtta ctgaaccaat cgaatacatg ttcatgttca tcgcaacacc tatgtatctt
     1261 gtttactcac ttgttcaagg tgctgccttc gctatggctg acgtcgtaaa cctacgtatg
     1321 cactcattcg gttcaatcga gttcttgact cgtacaccta ttgcaatcag tgctggtatt
     1381 ggtatggata tcgttaactt cgtttgggta actgttctct ttgctgtaat catgtacttt
     1441 atcgcaaact tcatgattca aaaattcaac tacgcaactc cagggcgcaa cggaaactac
     1501 gaaactgctg aaggttcaga agaaaccagc agcgaagtga aagttgcagc aggctctcaa
     1561 gctgtaaaca ttatcaacct tcttggtgga cgtgtaaaca tcgttgatgt tgatgcatgt
     1621 atgactcgtc ttcgtgtaac tgttaaagat gcagataaag taggaaatgc agagcaatgg
     1681 aaagcagaag gagctatggg tcttgtgatg aaaggacaag gggttcaagc tatctacggt
     1741 ccaaaagctg acattttgaa atctgatatc caagatatcc ttgattcagg tgaaatcatt
     1801 cctgaaactc ttccaagcca aatgactgaa gcacaacaaa acactgttca cttcaaaaat
     1861 cttactgagg aagtttactc agtagcagac ggtcaagttg ttggtttgga acaagtaaag
     1921 gatccagtat ttgctcaaaa aatgatgggt gatggatttg cagtagaacc tgcaaatgga
     1981 aacattgtat ctccagtttc aggtactgtg tcaagcatct tcccaacaaa acatgctttt
     2041 ggtattgtga cggaagcagg tcttgaagta ttggttcaca ttggtttgga cacagtaagt
     2101 cttgaaggta aaccatttac agttcatgtt gctgaaggac aaaaagttgc agcaggagat
     2161 ctccttgtca cagctgactt ggatgctatc cgtgcagcag gacgtgaaac ttcaacagta
     2221 gttgtcttca caaatggtga tgcaattaaa tcagttaaat tagaaaaaac aggttctctt
     2281 gcagctaaaa cagcagttgc taaagtagaa ttgtaatata cttgaggttg gaagctgtat
     2341 tccaacctct tattttggga gaaaagaatg aaatttttaa cactcaatac tcacagttgg
     2401 atggagaaag aagcagagga aaaattccag attttgcttg aagatattct tgaaaaggac
     2461 tatgatttga tttgtttcca agaaatcaat caggagatga cctcgtcaga ggtggaggtt
     2521 aatgaccttt atcaagcttt gccagcagct gagcctattc accaagacca ttatgttaga
     2581 ctcttggttg aaaagttgtt agagcaaggg aaaaattact actggacctg ggcttataac
     2641 catatcggct atgaccgcta ccacgaaggt gtggctatct tgtctaaaac acctattgaa
     2701 gccagagaaa ttttggtttc agatgtggat gatccaacag actatcatac tcgccgtgtt
     2761 gccctagctg aaactttagt cgatggcaag gagctagcag ttgccagtgt tcatctctct
     2821 tggtgggata aaggtttcca agaagaatgg gcacgatttg aggctgtctt gaaaaaattg
     2881 aacaagccac ttttactagc tggagatttt aacaacccag caggtcagga aggttaccaa
     2941 gctattttag ctagtccatt aggcttacaa gacgcatttg aagttgctca agagaaaagt
     3001 ggtagctata ctgttccgcc tgaaattgat ggctggaaag ggaacactga accccttcga
     3061 atcgattatg tctttactac caaagagtta gcggtggaaa atttacatgt cgtatttgat
     3121 ggtaacaaga gtccacaagt gagtgatcac tatggcttga atgctatgtt aaactggaaa
     3181 taataactga aaagaggttg gaactataaa attccagcct tttcttacta gagaagctac
     3241 tggaaatagc ctaaataagt gagactactg taatggaata aaatatggta taattgataa
     3301 gatagataga atcgaggatg ttatgtcatt tacgaaattt caatttaaaa actatattag
     3361 agaagccttg aaggagttaa aatttacaac tccaacagag gtgcaagata agttgattcc
     3421 tattgttttg gcaggtcgtg acctagtagg agaatcaaaa acaggttcag gtaagactca
     3481 tactttcttg ttaccgattt tccagcaatt agatgaagct agcgatagtg tacaagcagt
     3541 gattactgca ccgagtcgtg agttggctac tcaaatttac caagtagcgc gtcagatttc
     3601 agctcactca gatgtcgaag ttcgtgtggt taattatgtg ggtggtacgg ataaggctcg
     3661 ccagattgag aaattggcaa gcaatcagcc tcatattgtt attggaacac caggccgtat
     3721 ctacgacttg gttaaatctg gtgatttagc tattcataaa gccaagacat ttgttgttga
     3781 tgaagcagat atgaccttgg atatgggatt cttggaaatt gttgataaga ttgctggcag
     3841 tcttccaaaa gacttgcaat tcatggtctt ctcagcgact atcccacaaa aactgcaacc
     3901 attcttgaaa aaatacttat caaatcctgt tatggagaaa attaagacta aaacggttat
     3961 ttctgacacc attgataatt ggttgatttc gaccaaggga catgataaga atgctcaaat
     4021 ttaccaattg actcagttga tgcagccgta tttggcaatg atttttgtta acactaaaac
     4081 gcgtgctgat gaattgcatt catatctgac tgctcaaggc ttgaaggttg caaaaatcca
     4141 tggagatatt gcccctcgtg aacgcaagcg aatcatgaat caggtgcaaa atctggattt
     4201 tgagtatatt gtcgcaacag atttagcagc gcgtgggatt gacattgaag gtgtcagcca
     4261 tgtcatcaat gatgccattc cgcaagactt atcttttttt gttcaccgtg ttggtcgtac
     4321 tggacgaaat ggcctaccag gtacagctat taccctttat cagccaagtg atgactcgga
     4381 tatccgtgag ttggagaaat tgggaatcaa gtttagtcct aagatggtca aagatgggga
     4441 atttcaagat acctatgacc gtgatcgtcg tgccaaccgt gagaaaaaac aagataaact
     4501 tgatatcgaa atgattggtt tggttaaaaa gaaaaagaaa aaagtcaaac cgggttataa
     4561 gaagaaaatt caatgggcgg ttgatgaaaa gcgccgtaaa actaagcgtg ctgaaaatcg
     4621 cgctcgcggt cgtgcagagc gtaaagctaa acgccaaaca ttttaataga aattgttgga
     4681 gtactgagct ccaacttttt tatttatgag aacgaactat ctaaaccgaa acactacatt
     4741 aaagactgca aattgcgatt aaaaatggta taatgataaa gttatatagt cccgataaga
     4801 tggtaggtat ttattacgaa gagttttcct atcagtagtt tgcaattcgc aaagaatgac
     4861 ggcttcgagg tcgctcgtct ttctacggtt gccgccatac tgcggtcacc ctatgcgcct
     4921 tactagcttc agaaataaaa aagtatcgtt tttatttctg aagctagtaa ctcttagata
     4981 atggaaattc ctatcagtac tttgtaactc tataacaata ttttttaagg ggggacattt
     5041 ttatgtcaga acgtaaatta ttcacgtctg aatctgtatc tgaggggcat ccggataaga
     5101 ttgcagacca aatttcagat gcgattttgg atgctatttt agcaaaggat ccagaggcgc
     5161 acgttgctgc tgaaacagct gtatatactg gttctgtcca cgtttttggt gaaatttcta
     5221 caaatgccta tgtggatatt aaccgtgtgg ttcgtgatac cattgcagag attggttata
     5281 ccaatacaga atatggattt tctgctgaga cggtgggagt acacccatct ttggtggaac
     5341 aatctcctga catcgctcaa ggtgttaacg aagccttgga ggttcgtgga aatgctgatc
     5401 aagatccact ggacttgatt ggagcaggtg accaagggct catgtttgga tttgcagtag
     5461 atgaaacaga agagctcatg ccattgccaa ttgcactcag tcataaattg gttcgtcgtc
     5521 tggcagaact tcgtaagtct ggagaaatta gctatctccg tccagatgca aaatcacaag
     5581 ttacagttga gtacgatgaa aatgaccgtc cggtacgtgt agatacagtc gttatttcta
     5641 ctcagcatga tccagaggcc actaatgaac aaatccatca agatgtgatt gacaaggtca
     5701 tcaaagaagt tattccatct tcttatcttg atgataagac aaaattcttt atcaatccga
     5761 caggtcgttt tgtaatcggt ggtcctcaag gggactcagg tttgactggt cgtaagatta
     5821 ttgtagatac ttatggtggc tactctcgtc atggtggtgg tgccttctct ggtaaagatg
     5881 cgactaaggt ggatcgttca gcctcttatg cggctcgcta tattgccaag aatatcgttg
     5941 cagcaggcct tgctaagaag gcagaagtgc agttggccta tgctatcggt gttgcgcaac
     6001 ctgtttctgt tcgtatcgat actttcggta caggaacagt agctgaaagt caacttgaaa
     6061 aagcggctcg tcaaatcttt gaccttcgcc ctgcagggat tatccaaatg ctggacctca
     6121 agcgtccaat ttaccgtcaa acatcggctt acggtcacat gggacgtaca gatattgatc
     6181 ttccatggga acgtttggat aaggtagatg ctttgaaaga agcagtaaaa taagatttta
     6241 agaggggaac gtcctctctt ttttatagtt tttaactata ctgggatact gttctgaaaa
     6301 tccattttgc gaaagtagag atttacatgt ataatggatt gaaactagaa tagtacacct
     6361 caacttctaa aacattgtta gaaatcgatt tgactgtcct gatcgatttc tcctgttctt
     6421 gtttcatttt actatatttc tttaaaaatg ataaaggttg agatttctcc tcgtaataga
     6481 taatcatggg gatatttcaa tccaaagttt tattcgttat cacttgacta ttgcaaggtt
     6541 ttctagagca acagagtcat ggaatggact catggttgag atttctcctt gttgcttgga
     6601 cttcattcaa aagtctgtta cccaagcctt gttcaaactt ccaatacact agctgtttcc
     6661 atagcatgac ttctgtacta gactttcttt tccgaataaa tagatagaac cacagaatct
     6721 agtaaaccta gaattaaaat tatggtataa tattagcaat aaaagaaatc tggaggatta
     6781 gaatcatggt atcaacgaaa acacaaattg ctggttttga gtttgacaat tgcttgatga
     6841 atgcagcagg tgtggcttgt atgacgatag aggagttaga agaggtcaaa aactcagcgg
     6901 caggaacctt tgttactaag acagcgacct tggacttccg tcaggggaat cctgagccac
     6961 gctaccaaga tgttccactt ggttccatca actctatggg cttgccaaat aatggcttag
     7021 actattattt ggattatctt ttagatttgc aggaaaaaga gtcgaaccga actttcttct
     7081 tatctctggt cggcatgtct ccagaggaaa cccatactat tttgaaaaaa gtccaagaga
     7141 gtgattttcg tggtctgact gagctaaatc tttcctgtcc aaatgttcca ggtaaacctc
     7201 agattgccta tgattttgag acaacagacc ggattttggc agaagtgttt gcttacttca
     7261 ccaaacctct tggaattaaa ttgccacctt attttgatat tgttcacttt gaccaagcgg
     7321 cagctatttt caacaaatat ccgctcaagt ttgtcaactg tgttaactct atcggaaacg
     7381 gcctctatat agaagacgaa tctgtcgtta ttcggcctaa gaatggtttt ggtggaattg
     7441 gtggagaata catcaaaccg actgctctag ccaatgttca cgccttttat caacgtttaa
     7501 atcctcaaat ccaaattatc ggaacaggtg gcgttctgac tggtcgagat gcctttgaac
     7561 acatcctctg tggagcaagt atggtgcagg tgggaacgac ccttcacaaa gaaggcgtca
     7621 gtgcttttga ccgcattacc aatgaactga aagcaatcat ggtggaaaaa ggctacgaga
     7681 gcttagaaga tttccgtggg aaattgcgct atattgacta aattaaatcg aaaaatctga
     7741 agaaaggaga gacgatgcta gccattgaag aaagtcagaa gttgacttta tcaaatttac
     7801 cgagcctgag cctatttaca gggacagatc agggtcagtt tgaagtgatg aagagtcaag
     7861 tgttgaaaca gattgggtat gattctgctg acctcaactt tgcctacttt gatatgaaag
     7921 aagtagttta caaggatgtg gaactggagt tggtcagcct tcctttcttt gcggatgaga
     7981 aaatcgtgat attagattat tttatggata tcacgactgc taagaaacgc tttttgacag
     8041 atgatgagct taagtcattt gaggaatacc ttgacaattc ttctccaaca accaagttga
     8101 taatctttgc agaaggaaag ctggatagca aaagacggtt agtcaaatta cttaagcgtg
     8161 atgccaaggt cttcgatgca gtagaagtaa aagaacaaga attgcgccag tatttccaaa
     8221 agtggagtca gaaacaaggt ctgcagttta ccaatcattc ttttgaaaat ctcctcatca
     8281 agtcggggtt tcaatttagc gaaatccaga aaaatcttct ctttttacag tcctataagg
     8341 cgaattctgt tattgaggaa gaggatattg ttaacgcaat tcccaagacc ttgcaggaca
     8401 atatttttga tttaactcag tttattctga ctaaaaagat ggatcaggcg cgcgatttgg
     8461 tgagagactt gaccttgcaa ggggaagatg aaatcaaact gattgcagtc atgctgggac
     8521 aatttcggac ttttactcag gtgaagattt tggcggagtc tggccaaaca gaatcgcaga
     8581 ttgcaagtag tttaggtagt tatctgggac gtaacccaaa tccttatcaa atcaagtttg
     8641 cattaagaga ttcgagagga ctttctttga gctttctgaa gcaagctatt tcctatttga
     8701 ttgagacaga ctatcagatt aagacaggtc tttatgaaaa aggtttcctt tttgaaaagg
     8761 cactcttaca gattgctagt caggtcaatt gacatttgtt gaaactacaa cccgcgtcag
     8821 gattatcttg tcgtgggttt cttgctgatt tgcttatttt attagaaagt atgtcagtga
     8881 tttccttatc tataagcaaa aaacttgaaa aaagtgaatg tttgcgttat cattttcata
     8941 tagaaagaaa aagaggtatt acagatggct attatcttac cagaacttcc atatgcatac
     9001 gacgctttgg aaccatacat cgatgcggaa acaatgcatt tgcaccatga caaacaccat
     9061 caaacttatg tcaacaatgc caatgcagct ttagaaaaac accctgaaat cggtgaagac
     9121 cttgaagcct tgcttgctga tgtagaatct atcccagctg atatccgtca agcacttatc
     9181 aacaatggtg gcggacactt gaaccacgct cttttctggg aattgatgac tcccgagaaa
     9241 acagctcctt cagcagaact ggcagcagca atcgatgcaa catttggttc atttgaagaa
     9301 ttccaagcag ccttcactgc agcagcaaca actcgttttg gttcaggttg ggcatggttg
     9361 gttgtcaaca aagaagggaa acttgaagtg acttcaacag caaaccaaga cacaccaatc
     9421 tcagaaggta aaaaaccaat cttgggcttg gacgtttggg aacatgctta ctacgtgaaa
     9481 taccgcaacg tgcgtcctga ctacatcaaa gctttctttt cagtaatcaa ctggaataaa
     9541 gtagatgaat tgtacgcagc tgctaaataa tgatagttgg agggaagaat tgttcttctc
     9601 tttttaggtt ataagattct ggtctgacaa aatcgtcaga cttttttcat ttttatgaga
     9661 aacgtgctaa ctgctagaaa ttatggtaga ataaagtatt aagtaatcgt ggaaaaagga
     9721 tatctatgcg aaaagaaatt gcacctgaat tatacaacta taacaagttt cctggtccgg
     9781 agttccattt acacggggat aaggtcgaaa cggaagggat agctttttcc ttggttgaaa
     9841 atatcaagga tgcctttgat gtgacgactt ttaatcagcg tttttcagaa gtcttaacca
     9901 agtttgatta tatcgtgggg gactggagca acgaacagct tcgcctacga ggtttttaca
     9961 aggatgaccg aacagaagaa aaacttgaaa aaatcagtcg tttacaagac taccttttag
    10021 agtattgtag ttatggttgt gcctattttg tcttagaaaa tgaagcccct aagcgagcat
    10081 catttgacaa gaaaatgcgt aagacggaag aagaaacacc ttctagaaaa ggaaagaaac
    10141 cgactcaaac taaacgaaag tcgaatgcag ataagaaaaa tagacgtcgt cagaaagacc
    10201 agcattctca gaaagaggac aaggaacaac gtcattttgt cattcgtcag aagtgagtag
    10261 agaataagga gaagaaatga aaccctcaat tcatagtttg gcacatcaaa ccatgcagga
    10321 atgggtattg gagcagggag aaaagaaatt ccgtgcagat caaatctggg aatggctcta
    10381 ccgtaaacgt gtgcagtcat ttgaagaaat gaccaacctt tccaaggatt tgattgctaa
    10441 gctcaatgac cagtttgtgg tcaatccctt gaaacaaggt attgtgcaag agtctgctga
    10501 tggtacagtc aaatatctct ttgaattgcc tgacggtatg ttaattgaga ctgtactcat
    10561 gtgtcaacac tatggtttat ctgtctgtgt gaccactcag gtcggctgta atatcggttg
    10621 taccttctgt gcctctggtt tgattaagaa gcagcgtgac ctcaataacg gtgaaatcgt
    10681 agcgcaaatc atgctggttc agaaatactt tgatgagcgt ggtcaggatg aacgcatcag
    10741 ccatatcgtt gtcatgggaa tcggtgagcc ctttgataat tacaacaatg tcttgaattt
    10801 ctttcgtact atcaatgatg ataaaggaat ggctatcggt gctcgtcaca tcacggtttc
    10861 aatctcaggt ttggctcata aaattcgtga ctttgctgat gaaggggttc aggtcaatct
    10921 tgccgtgtct cttcacgcac ccaacaatga acttcgttca agtatcatga agattaaccg
    10981 tgcctttcc
//
LOCUS       DAVBBO010000065        10791 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ST1
            SAMEA2066453-rid20184263.denovo.065, whole genome shotgun sequence.
ACCESSION   DAVBBO010000065 DAVBBO010000000
VERSION     DAVBBO010000065.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2066453
            Sequence Read Archive: ERR351777
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 10791)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10791)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980402.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980402.1
            Genome Coverage       :: 176x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:17:33
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,141
            CDSs (total)                      :: 2,104
            Genes (coding)                    :: 1,953
            CDSs (with protein)               :: 1,953
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 16S)
            partial rRNAs                     :: 1 (23S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 151
            CDSs (without protein)            :: 151
            Pseudo Genes (ambiguous residues) :: 0 of 151
            Pseudo Genes (frameshifted)       :: 73 of 151
            Pseudo Genes (incomplete)         :: 76 of 151
            Pseudo Genes (internal stop)      :: 40 of 151
            Pseudo Genes (multiple problems)  :: 32 of 151
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10791
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2066453-rid20184263.denovo.065"
                     /strain="ST1"
                     /db_xref="taxon:1313"
     gene            135..425
                     /locus_tag="VQU30_001875"
     CDS             135..425
                     /locus_tag="VQU30_001875"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014632364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2447926.1"
                     /translation="MELKDFTEKEQEMIKKRLTMSNISDKETTEKILALVPQDLIKRI
                     PFFVRKHATTRTIKRISIEYPELYAVAQTSGEIPEKNAKNCVRLSQLSLNKR"
     gene            449..1165
                     /locus_tag="VQU30_001876"
     CDS             449..1165
                     /locus_tag="VQU30_001876"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000759776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HET2447927.1"
                     /translation="MKKYFIGGLGSNAYHSKDFLQELDSQVYFLNPYEKHLRDETELK
                     SWFKNEIVEEESICLIGHSIGGDLARYFASEFEEVKKLILLDGGYLDLDKILPLDTEL
                     EETKNYIKSQIISDLDVLTSKEKSEAKHWSENMEKAVRQSYHWNVEYNRYELAINYEN
                     IEAILRLRRKIQAFKREVGDTLFISPRYPNEATWREEALKELPDYFDTIFLENFGHEL
                     YTQAPKEIASLMNEWLAYFL"
     gene            complement(1294..2109)
                     /locus_tag="VQU30_001877"
     CDS             complement(1294..2109)
                     /locus_tag="VQU30_001877"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000617844.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR03943 family protein"
                     /protein_id="HET2447928.1"
                     /translation="MIRFLVLAGYFELTIYLHLSGKLNQYINMHYSYLAYISMVLSFI
                     LAIVQLYIWMKQVKTHSHLNSRLAKMTSISLLAIPLVIGLTFPTVSLDSQTVSAKGYH
                     FPLSEGTDLAIQTSEGTTSQYLKPDTSSYFSKSAYEKEMRTAADKYLSQDSIQITNEN
                     YMEVMEAIYDYPDEFEGKTIQFTGFVYNDPSHANSQFLFRFGIIHCIADSGVYGLLTK
                     GNTRQYENNTWITAKGKLVNHYHKELKQNLPTLEIDSFTKVDKPENPYVYRAF"
     gene            complement(2106..3011)
                     /locus_tag="VQU30_001878"
     CDS             complement(2106..3011)
                     /locus_tag="VQU30_001878"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398535.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="permease"
                     /protein_id="HET2447929.1"
                     /translation="MTAFQQLPSSVLQTGAIFLSIIIEALPFVLIGSIVSGLIEVYIT
                     PDKVYHFLPRNRWGRIFFGTFVGMLFPSCECGIVPIINRFLEKKVPSYTAVPFLVTAP
                     VINPIVLFATYSAFGNSFHVALLRALGSILVAVILGIFLGFFWQEPIQKENRLACHEH
                     DFSYLSSAKKVFQVFVQAIDEFFDTGRYLVFGCLFASIIQVYVPTRILTSISATPLFA
                     ILLLMILAFLLSLCSEADAFIGASLLSSFGLAPVLAFLVIGPMLDIKNILMMKNYLKA
                     RFISHFITIVTLVVLVYSLLIGVIL"
     gene            complement(3282..3365)
                     /locus_tag="VQU30_001879"
                     /pseudo
     CDS             complement(3282..3365)
                     /locus_tag="VQU30_001879"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820552.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopyranose mutase"
     gene            3409..5538
                     /locus_tag="VQU30_001880"
     CDS             3409..5538
                     /locus_tag="VQU30_001880"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000359105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding transcriptional accessory protein"
                     /protein_id="HET2447930.1"
                     /translation="MDKKYEKISQDLGVMLKQIDTVLSLTAEGATIPFIARYRKDMTG
                     SLDEVAIKAIIDLDKSLTNLNDRKEAVLAKIQEQGKLTKELEEAILVAEKLADVEELY
                     LPYKEKRRTKATIAREAGLFPLARLILQNIVDLEKEAEKFVCEGFATGKEALTGAVDI
                     LVEALSEDVTLRSMTYQEVLRHSKLTSQAKDESLDEKQVFQIYYDFSETVGTMQGYRT
                     LALNRGEKLGVLKIGFEHATDRILAFFATRFKVKNAYIDEVVQQSVKKKVLPAIERRI
                     RTELTEKAEEGAIQLFSDNLRNLLLVAPLKGRVVLGFDPAFRTGAKLAVVDATGKMLT
                     TQVIYPVKPASARQIEEAKKDLADLIGQYGVEIIAIGNGTASRESEAFVAEVLKDFPE
                     VSYVIVNESGASVYSASELARQEFPDLTVEKRSAISIARRLQDPLAELVKIDPKSIGV
                     GQYQHDVSQKKLSESLDFVVDTVVNQVGVNVNTASPALLSHVAGLNKTISENIVKYRE
                     EEGKITSRAQIKKVPRLGAKAFEQAAGFLRIPESSNILDNTGVHPENYTAVKELFKRL
                     DIKDLNEEAQSKLKSLSVKEMAQELDLGPETLKDIIADLLKPGRDFRDSFDAPVLRQD
                     VLDIKDLVVGQKLEGVVRNVVDFGAFVDIGIHEDGLIHISHMSRKFIKHPSQVVSVGD
                     LVTVWVKKIDTEREKVNLSLLAPNETD"
     gene            5525..5974
                     /locus_tag="VQU30_001881"
     CDS             5525..5974
                     /locus_tag="VQU30_001881"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000778579.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SprT family protein"
                     /protein_id="HET2447931.1"
                     /translation="MKLTDYVKQVSLEDFGRAFIHHVQWNRRLRSTGGRFFPKDGHLD
                     FNPKVYQKLGMEVFRKIVRHELCHYHLYFQGKGYQHKDRDFKELLKAVDGLRFVPSLP
                     NSNSKPLKLYRCQSCQQRYQRKRRIDTKRYRCGLCRGKLLLINQPED"
     gene            6033..6305
                     /locus_tag="VQU30_001882"
     CDS             6033..6305
                     /locus_tag="VQU30_001882"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269704.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PspC domain-containing protein"
                     /protein_id="HET2447932.1"
                     /translation="MNSKFYKMRRNRMISGVLAGLSDKWNFDVTLVRFLFAIFTVANF
                     GLGVIIYIILASIMPTKEEIEAEMYGTGPRKRKEAQAIDDNEGWFW"
     gene            complement(6659..6850)
                     /locus_tag="VQU30_001883"
     CDS             complement(6659..6850)
                     /locus_tag="VQU30_001883"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000680763.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2447933.1"
                     /translation="MKHKEHILIGLLYLLSPFIGQLLVEHTHFIGTEFTGTAYVICWL
                     SVVISIHHFSKNVLSQQQK"
     gene            7278..8036
                     /locus_tag="VQU30_001884"
     CDS             7278..8036
                     /locus_tag="VQU30_001884"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000173375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET2447934.1"
                     /translation="MTLLDVKHVQKIYKTRFQGNQVEALKDIHFTVEKGDYVAIMGES
                     GSGKSTLLNILAMLDKPSRGQVYLNGTDTATIKNSQASSFRREKLGFVFQDFNLLDTL
                     SVKDNILLPLVLSRRPITEMMKKLVVTAENLGINQLQEKYPYEISGGQKQRVAVARAI
                     ITEPEILLADEPTGALDSKSSAALLDVFDEINERGQTILMVTHSTAAASRAKRVLFIK
                     DGILYNQIYRGEKTERQMFQEISDTLTVMASEVN"
     gene            8038..10026
                     /locus_tag="VQU30_001885"
     CDS             8038..10026
                     /locus_tag="VQU30_001885"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000489335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HET2447935.1"
                     /translation="MFRLTNKLAVSNLIKNRKLYYPFALAVLLAVTVTYLFYSLTFNP
                     KIAEIRGGTTIQATLGFGMFVVTLASAIIVLYANSFVMKNRSKELGIYGMLGLEKRHL
                     ISMTFKELVVFGILTVGAGIGIGALFDKLIFAFLLKLMKLKVELVATFQTKVVITVLV
                     VFGLIFLGLMFLNALRIARMNALQLSREKASGEKKGRFLPLQTILGSISLGIGYYLAL
                     TVKDPLTALTTFFIAVLLVIFGTYLLFNAGITVFLQILKKNKKYYYQPNNLISVSNLI
                     FRMKKNAVGLATIAILSTMVLVTMSAATSIFNSSESFKKVLNPHDFGVSGQNVEKEDL
                     DKLLSQFASDKGYSVKEKEVLRYSNFGIANQEGTKLTIFEKGQNRVQPKTVFMVFDQK
                     DYENMTGQKLSLSGNEVGLFAKNEGVKEQKALTLNDHQFSVKEEFTKDFIVNHVPNQF
                     NILTADYNYLVVPDLQAFLDQFPDSAIYNQFYGGMNVNASEAEQLKVAEEYEKYLQKF
                     NAQLNTEGNYVYGSTLADASAQMSALFGGVFFIGIFLSIIFMVGTVLVIYYKQISEGY
                     EDRERFIILQKVGLDQKQIKQTINKQVLTVFFLPLLFAFLHLAFAYHMLSLILKVIGV
                     LDTTMMLIVTLSICAIFLIAYVLIFMITSRSYRKIVQM"
     gene            complement(10068..10712)
                     /locus_tag="VQU30_001886"
     CDS             complement(10068..10712)
                     /locus_tag="VQU30_001886"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000234620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VIT family protein"
                     /protein_id="HET2447936.1"
                     /translation="MLRAGVLDANDGIISIAGVVIGVASATTNIWIIFLSGFAAILAG
                     AFSMAGGEYVSVSTPKDTEEAAVSREKLLLDQDRELAKKSLYAAYIQNEEFKTSAQLL
                     TNKIFLKNPLKALVEEKYGIEYEEFTNPWHAAISSFVAFFLRSLPPMLSVTIFPSDYR
                     IPATVLIVGVALLLTGYTSARLGKAPTKTAMIRNLAIGLLTMGVTFLLEQLFSI"
BASE COUNT         3339 a         2019 c         2255 g         3178 t
ORIGIN      
        1 tataccatat tttgtttcgc aggaagtcta atgctaaaat cttatcagtg agaagatttc
       61 ttaaagttta ttctttgtag tttcatctgt attagtacat aatttaactt agagaaaata
      121 ggaggactaa tcgaatggaa ttaaaagatt ttacagaaaa agaacaggaa atgattaaga
      181 aaaggcttac aatgtctaat attagtgaca aagaaactac tgagaagatt ctggcgctag
      241 tcccacaaga cttgattaag cgaatcccgt tttttgtcag aaaacatgct acaacacgta
      301 cgattaaacg tatttcaatt gaataccctg aactctacgc tgtagctcaa acaagtggtg
      361 agattccaga aaaaaacgcg aagaattgcg tcagattatc acaactatct ttgaacaaaa
      421 gatgaataag catagtatta agtagagaat gaaaaaatat tttattggcg gtttgggaag
      481 caatgcctat catagcaagg attttcttca agaactagat tcgcaggtct attttctaaa
      541 tccatatgaa aagcatcttc gagatgaaac agaattgaaa tcatggttta aaaatgagat
      601 tgtagaggaa gaatctatct gtctgatagg tcattctatt ggaggcgatt tagctcgtta
      661 tttcgcatcg gaatttgaag aagtaaagaa actgattctt ttggatggtg gctatctaga
      721 tttagataag attttacctt tggatacaga gttagaggaa actaaaaatt atatcaaatc
      781 tcaaattatt tcggacttag atgttcttac ttctaaagaa aaatctgaag caaagcattg
      841 gtcagaaaat atggagaaag ctgtaagaca gtcctatcac tggaatgttg agtataatag
      901 atatgagttg gctataaatt atgaaaatat agaagcgata ctccgcctac ggagaaaaat
      961 acaagctttt aagagagaag tgggagatac cttgtttatt agtcctcgct atcctaatga
     1021 agctacatgg agagaggaag ccctaaaaga attgccagac tattttgata ctattttttt
     1081 agaaaacttt ggccatgagc tttatactca agcacctaaa gaaatcgcta gtctaatgaa
     1141 tgagtggctc gcttattttc tatgagctac ttgtattgct ggaaatggta taagatgaaa
     1201 atctacaagt cactaatttt catataacaa aaaacgaaca ggctcttttt ctgttattca
     1261 gaagagaact tgttcgtttt tatcttgatt ttcttaaaaa gctctatata catagggatt
     1321 ttctggttta tcgactttgg taaagctgtc gatttccaag gttggaaggt tttgtttgag
     1381 ttctttatgg tagtgattga ccagttttcc tttggctgtt atccaagtgt tgttttcata
     1441 ctgccgggta ttgcccttgg tcagcaatcc atagacacca gaatctgcga tacagtggat
     1501 aatgccgaat cggaacagaa attgactatt ggcatgactg gggtcgttat agacaaagcc
     1561 tgtaaactgg attgtcttgc cctcaaactc atctggatag tcgtagatag cctccatgac
     1621 ttccatatag ttttcattag tgatctgaat actatcttgg gataagtatt tatccgccgc
     1681 cgttcgcatt tccttttcat aggctgattt tgaaaaataa gaactggtat ctggtttcaa
     1741 atattggctt gtcgtccctt cgcttgtctg aatggctaga tctgttcctt ccgatagggg
     1801 gaaatgataa cctttagcag aaacggtctg agaatccaag ctaacagttg ggaaagttaa
     1861 gccgatgaca agtggaatag ccagaagaga aatactcgtc atcttggcca atcggctgtt
     1921 cagatgactg tgggttttga cttgcttcat ccagatatac aattgaacaa ttgccaagat
     1981 aaaggaaagc accatggaga tataggccag ataggaatag tgcatgttga tgtactggtt
     2041 tagtttgccc gacagatgga ggtaaatagt cagttcaaaa tagccagcta aaactaaaaa
     2101 tcgaatcata ggatgactcc aatcaagaga gaatagacta agacgacaag agttacaatc
     2161 gttatgaagt gactgataaa tcgtgctttc aagtaatttt tcatcatgag aatatttttg
     2221 atatccagca ttggaccaat gacgagaaag gccagaactg gtgccaaacc gaaactcgag
     2281 agaagagaag cacctataaa ggcatccgcc tcactacaga gcgaaagaag aaaggccaaa
     2341 atcatcaaga gcaggatggc aaaaagagga gtcgcactga tagaggtcag aatccgagtc
     2401 ggaacgtaga cctgtattat agaagcaaag aggcagccaa ataccaaata acgccccgta
     2461 tcaaaaaatt catcaatggc ctgcacaaag acttgaaaaa ctttttttgc agaactcaag
     2521 taagaaaaat catgctcatg acaagccaga cgattttctt tctgaatcgg ttcttgccag
     2581 aaaaatccta gaaaaattcc tagtattaca gccacaagaa tggaacccag agctcgtaat
     2641 agggcgacat ggaaggagtt gccaaaggca gaataggtcg caaaaagaac aatgggattg
     2701 ataacaggtg ctgtcacaag aaaaggaacg gctgtgtaac tgggaacctt tttttccaga
     2761 aaacgattga tgatggggac gattccacat tcacaagaag ggaaaagcat accgacaaag
     2821 gtcccaaaaa agattctccc ccaacgattt cgagggagaa aatgataaac cttgtcaggt
     2881 gtgatataaa cttcaatcag ccctgagaca atgcttccta ttagaacgaa gggaagggct
     2941 tcaatgataa tggagagaaa aatggctcca gtttgaagta cactagatgg gagttgttga
     3001 aaagcagtca tctagttttt cttttctgct ttggcttttt tctctttgtc atcagggaaa
     3061 gtaacttgtt tcaaatcagg gagtttagca aactcttcaa acatcttgtc caagtcgtct
     3121 cgttttgtaa attttacagc cataggtgta cctcgattct aaagtctacc tctattatac
     3181 tattattttg cggaaaaggg agttttttaa tttgttttcg atagttgata cacttcgaaa
     3241 atctcttcaa accacgtcag cttcgcctta ccgtatatat gtgacttatc cacaacctca
     3301 aaacagtatt ttgagcagcc tgcggctagc ttcctagttt gctttttgat tttcattgag
     3361 tatgaaaagg attggagaaa gccttccagc ttgtggtata atagatttat ggataaaaaa
     3421 tatgaaaaaa tctctcagga tttgggagtg atgttaaagc aaattgatac cgttctaagt
     3481 ttgacagctg aaggggcgac tattcccttt atcgcgcgtt atcgcaagga catgactggt
     3541 agtctggatg aggtggcgat taaggctatt attgatttgg ataaaagtct gacaaatctc
     3601 aatgaccgta aggaagctgt cttagctaag attcaagaac aaggtaagtt gaccaaggaa
     3661 ttggaagaag ctatcttagt tgccgaaaaa ttagcagacg ttgaagaact ctatcttcct
     3721 tataaggaaa agcgtcgtac caaggcaacc attgcccgtg aagctggact ctttcctctt
     3781 gctcgtttga ttttgcagaa tatagttgac ttagagaaag aagctgaaaa gttcgtctgt
     3841 gaaggatttg cgactggcaa ggaagccttg accggtgcag ttgatatttt ggtcgaagcc
     3901 ttatcggaag atgtgacctt gcgttctatg acttatcagg aagtgctgag acactctaaa
     3961 cttacttctc aagccaagga tgaaagtctt gatgaaaagc aggtttttca gatttattat
     4021 gatttttcag agacagttgg aactatgcaa ggctatcgta ccttggctct caatcgtggg
     4081 gagaaacttg gtgtcttgaa gatcggtttt gaacatgcga cggaccgtat tcttgccttc
     4141 tttgctactc gtttcaaggt gaaaaatgct tatattgatg aagttgttca gcaatccgtt
     4201 aagaaaaagg tcttgcctgc tatcgagcgt cgtattcgga cagaattaac tgagaaagct
     4261 gaagaaggag ctatccaact tttttctgac aatctgcgca atctcctctt ggttgctcca
     4321 ctgaaagggc gcgtggttct tggatttgac ccagcctttc gtacaggtgc caagttagct
     4381 gtcgtggatg caacaggaaa aatgctgaca actcaggtta tttatcctgt taaaccagca
     4441 tcagctcgtc aaatcgaaga agccaagaaa gatttagcag atttaattgg tcaatacggt
     4501 gtagagatta ttgccattgg aaatggaacg gccagtcgtg aaagtgaagc ttttgtagcg
     4561 gaagttctga aagatttccc tgaagtcagc tatgttatcg ttaatgaaag tggtgcttct
     4621 gtctattctg ccagcgaact tgctcgtcag gagtttccag acttgaccgt tgaaaaacgc
     4681 tctgccattt ctatcgcccg tcgtttgcaa gatcctcttg cggaattggt caaaatcgat
     4741 cctaagtcaa ttggtgtcgg tcaataccaa cacgatgtca gtcagaagaa actatctgag
     4801 agtctggact ttgttgtcga tacagtggtt aaccaagttg gtgtcaatgt caatacagct
     4861 agcccagctc ttctttcaca cgtagctgga ctcaacaaaa ctatctctga aaatattgtc
     4921 aaataccgcg aggaagaagg aaaaatcact tcacgcgccc aaatcaagaa agttcctcgt
     4981 ctgggagcca aggcctttga gcaggctgct ggtttccttc gtatccctga aagtagcaat
     5041 atccttgata atacaggagt tcacccagag aattacactg cagttaagga actcttcaaa
     5101 cgtttagata ttaaagacct aaacgaagaa gcccaaagca aactcaagtc cctttcagtc
     5161 aaggaaatgg ctcaagagct agacctcggt ccagaaaccc ttaaagatat cattgcagat
     5221 cttctcaaac caggtcgaga tttccgtgat tcctttgacg cacctgtgct tcgccaagat
     5281 gtcctagata tcaaagacct agtggtaggt cagaagctag aaggtgttgt gcgtaacgtt
     5341 gttgacttcg gtgccttcgt tgatatcggg attcacgagg acggcttgat tcatatttct
     5401 catatgagtc gcaagtttat caaacaccct agtcaagtgg tgtcagttgg agatttggtg
     5461 accgtttggg tcaagaaaat tgatactgaa cgtgaaaaag ttaatctgtc gctcctcgct
     5521 ccaaatgaaa ctgactgatt atgtcaagca ggtttcacta gaagacttcg ggagagcttt
     5581 tatccatcat gtccagtgga ataggcgtct acgttcgaca ggtgggcgat ttttccccaa
     5641 agatgggcat ctggatttta atcccaaggt ttatcagaaa ctgggtatgg aggtttttag
     5701 gaaaattgtc cgacatgaac tctgtcatta tcacctttat ttccaaggga agggctatca
     5761 acacaaggat cgggatttta aggaactgtt gaaagcagtg gatggattaa ggtttgtacc
     5821 atccttgccc aatagtaact ctaaaccact caagctttat cgttgtcaat cctgccagca
     5881 aaggtatcag cgcaagcgta ggattgatac caaacgctat cgctgtggac tttgtcgagg
     5941 taaattgctt ctgataaatc agcctgagga ctgatgaaag ccgagcctcc ccgtgatata
     6001 ctatgtctaa cctagcagaa agaggaaata tcatgaacag taaattttat aaaatgagac
     6061 gcaatcgcat gatttcagga gttctggcag gtctgtcaga caagtggaat tttgatgtta
     6121 ccctagttcg tttcttgttt gccattttta cagttgcaaa ctttggactt ggcgtgatta
     6181 tctatatcat cctagcttct atcatgccta ccaaggaaga aatcgaagca gaaatgtacg
     6241 gaacaggccc acgtaaacgc aaagaagccc aagccattga cgacaatgaa ggctggtttt
     6301 ggtgaggttc tacagaagat ttggaataag caaaaagctt taaatcaata gtctaaactg
     6361 cttgatttaa agctttttta cttttatact caataaaaat caaagtgcaa actaggaagc
     6421 cagccacagg ctgtaattta gtcggcaatg tgaagttgac atagtttgca ctttgatttt
     6481 tgaatagtat taataatatt tcgccagctt catccacaaa ctatagtgga ttggaactag
     6541 aatagtacac ctctacttct aaaacattgt tagaaatcga tttgactatc ctgatcgatt
     6601 tgtcctgttc ttatttcatt ttattataaa agcagtaatt taaactcagt tttttaatct
     6661 atttttgctg ctgagacaat acatttttgg aaaaatggtg gatgctgata acaactgata
     6721 accagcaaat aacataagca gtgccggtaa attctgtacc gataaagtgt gtgtgttcaa
     6781 ctaagagctg accgatgaat ggagagagca gatagagaag tccgatgagt atatgttctt
     6841 tgtgtttcat taaagcgcac cttctttcct tataggttga acgacttgca agtgttaaat
     6901 tgaatggtat gttatctagg taagcttact caaatgatag ttcccgcttc ctcctttcca
     6961 aagtaagcct tttcatactt atattttaca actttaaaaa taggaaatca aatcattttc
     7021 taagtaattt tgcttatatt tcacccaatc ttacaaaaat gtaagattaa agtctctttt
     7081 gtaaggttag gttatggcaa gcggtctttt tttgatgtaa actagactca taaagaacaa
     7141 aggagtaaca tcatgaaaca aatcttacat aagaaaacta gaaaaccaag tcacaaagaa
     7201 attgagcgcg ttcagctggg atgcactatg atgcaagcta catttcattt gatgggatat
     7261 taagaaagga gattctcatg acacttttag atgtaaaaca cgttcaaaaa atttataaaa
     7321 cacgttttca gggcaaccaa gtagaagccc tcaaggatat tcactttacc gtcgaaaagg
     7381 gtgactacgt tgccatcatg ggtgagtctg gttctggtaa atcaactctt ctcaatattc
     7441 tagctatgct ggataaacca agtcgtggtc aggtttactt gaatggaact gacaccgcaa
     7501 ccattaaaaa ttcacaggcc tctagcttcc gtcgtgaaaa gttgggcttt gtcttccaag
     7561 actttaactt gctagatact ctatctgtaa aggacaatat cttgcttccg cttgtcttgt
     7621 caagaagacc tattacagag atgatgaaga aattggtggt gacagctgag aatctgggaa
     7681 taaaccaatt acaagagaag tacccttacg agatttctgg tggccagaaa cagcgtgtag
     7741 cagtagcacg cgccatcatc actgaacctg aaattctcct tgcggacgaa ccgacaggag
     7801 ctcttgactc caagtcatct gcagccttac ttgatgtctt tgatgaaatc aatgagcgcg
     7861 gccaaaccat tctcatggta acccactcaa cagcagcagc tagcagagct aaacgtgtac
     7921 tctttatcaa agacggcatt ctttacaatc aaatctaccg tggagagaag acagaacgtc
     7981 agatgttcca agaaatctct gataccttga ctgtcatggc aagcgaggtg aattagtatg
     8041 tttcgattaa ccaataagtt agcggtatcg aacttgatta aaaaccgcaa actctactat
     8101 ccttttgcgc tggctgttct cttggcagtc actgtcacct atctctttta ctctctaacc
     8161 ttcaatccca agattgctga aattcgtgga ggaacaacca ttcaggctac acttggattt
     8221 ggtatgtttg tcgtcaccct tgcgtcagcc attatcgttc tctatgccaa tagttttgtc
     8281 atgaagaacc gttccaagga actaggaatt tatggcatgt tgggcttgga gaagcgtcat
     8341 cttatcagta tgacctttaa ggagttagtg gtatttggga ttctaactgt tggagcgggt
     8401 atcggtattg gagccttgtt tgacaagtta attttcgctt tcctgctcaa actaatgaaa
     8461 ttgaaggttg agctggttgc taccttccag acgaaagttg tcattacagt gcttgttgtc
     8521 ttcggtttga ttttcctagg cctcatgttc ctgaatgccc ttcgaatcgc ccgtatgaat
     8581 gccctccagc tctctcgtga gaaagctagt ggagagaaaa aaggtcgctt ccttcctctc
     8641 caaaccattc ttggttccat aagtttagga attggctatt atcttgccct tacggtaaaa
     8701 gatcctctta cagccttaac aaccttcttc atagctgttt tactggttat ctttgggact
     8761 tatctcttgt ttaatgcagg gattaccgtt ttcctccaaa tcttaaagaa aaataagaaa
     8821 tactattacc aaccaaataa tctcatatct gtttctaact tgattttccg tatgaagaaa
     8881 aatgcagttg gactagccac catcgctatc ttgtcaacaa tggttttggt aaccatgtca
     8941 gcagcgacaa gcattttcaa ttcctcagaa agctttaaaa aagttctaaa tcctcatgat
     9001 tttggggttt cagggcaaaa tgttgaaaaa gaagacttgg acaaactctt gagccagttt
     9061 gcaagtgaca aaggttatag tgtcaaagag aaagaagtac ttcgttacag taactttggt
     9121 attgcaaatc aagaaggaac taagttaact atttttgaaa aaggacaaaa ccgtgtccaa
     9181 ccaaaaacag ttttcatggt atttgaccaa aaagattatg aaaatatgac tggtcaaaaa
     9241 ctgtctctat caggaaatga ggtcggactc tttgcaaaga atgagggagt taaagaacag
     9301 aaagctctaa ctctaaatga tcatcaattt tctgtaaaag aagaatttac taaagatttt
     9361 attgtcaacc atgttccaaa tcagtttaat attttgactg ctgattacaa ttaccttgtt
     9421 gtacctgatt tacaagcctt tttggatcaa ttcccagatt cggctatcta taatcagttt
     9481 tacggtggta tgaatgtaaa tgccagtgaa gcagaacaac tcaaggtcgc tgaggagtat
     9541 gaaaaatact tacaaaagtt taatgctcaa ttaaacactg aaggtaacta tgtgtatggt
     9601 agcactctag cagatgctag tgctcagatg agtgccctct ttggtggtgt cttctttatc
     9661 ggtattttct tatccattat ctttatggtc ggaaccgttc tggtcatcta ctacaaacaa
     9721 atttctgaag gatatgaaga ccgtgagcgc tttattatct tgcagaaagt cggtttagat
     9781 caaaagcaaa tcaagcaaac catcaacaaa caggttttaa ctgtattctt ccttcctttg
     9841 ctctttgcct tcctacatct agcctttgcc taccatatgc ttagtctgat tttaaaagtg
     9901 attggtgtac tggatacgac tatgatgttg attgtgacct tgtctatctg cgctatcttc
     9961 ctcatcgcct atgtgctgat tttcatgatt acttcaagaa gttatcgcaa gattgtgcaa
    10021 atgtaaaaaa gatacctcga cttcaaaatc gaggtatttc ttgtattcta aatgctgaaa
    10081 agttgttcga gcaggaaggt aactcccatg gtcaagagac caatagcaag gttccgaatc
    10141 atagctgttt tggttggggc ttttccaagt ctagcacttg tgtaaccagt gagaagaagg
    10201 gccacaccga caataaggac ggtagcaggg atgcggtaat cacttggaaa aatggtcact
    10261 gacagcattg gaggcaaact tctaaggaaa aaggcaacga agctagaaat ggcagcgtgc
    10321 caaggattgg taaattcttc atactcaatc ccatattttt cctctaccag agccttgagt
    10381 ggatttttaa gaaagatctt attagtcaag agttgggcag aagttttgaa ttcttcattt
    10441 tggatataag cagcatagag ggattttttg gctagttccc tatcttggtc tagcaagagt
    10501 ttttctcgcg aaacggcagc ttcctcggta tcttttggag ttgaaacgga tacatattct
    10561 ccaccagcca ttgaaaaggc accagctaag atagccgcaa atcctgataa aaagataatc
    10621 cagatattgg tcgtggcact ggcaaccccg ataaccacac cagcaatgga aataattcca
    10681 tcgttagcat caagaacacc cgcacgcagg atatttaaac gacctgcaaa atttgaatca
    10741 atttcgtgat ttgtttctga cgctaaattt caagttcaag ttagccatcc a
//
LOCUS       DAVBBO010000066        10604 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ST1
            SAMEA2066453-rid20184263.denovo.066, whole genome shotgun sequence.
ACCESSION   DAVBBO010000066 DAVBBO010000000
VERSION     DAVBBO010000066.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2066453
            Sequence Read Archive: ERR351777
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 10604)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10604)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980402.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980402.1
            Genome Coverage       :: 176x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:17:33
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,141
            CDSs (total)                      :: 2,104
            Genes (coding)                    :: 1,953
            CDSs (with protein)               :: 1,953
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 16S)
            partial rRNAs                     :: 1 (23S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 151
            CDSs (without protein)            :: 151
            Pseudo Genes (ambiguous residues) :: 0 of 151
            Pseudo Genes (frameshifted)       :: 73 of 151
            Pseudo Genes (incomplete)         :: 76 of 151
            Pseudo Genes (internal stop)      :: 40 of 151
            Pseudo Genes (multiple problems)  :: 32 of 151
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10604
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2066453-rid20184263.denovo.066"
                     /strain="ST1"
                     /db_xref="taxon:1313"
     gene            complement(7..1221)
                     /locus_tag="VQU30_001887"
     CDS             complement(7..1221)
                     /locus_tag="VQU30_001887"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011836593.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HET2447937.1"
                     /translation="MKEYNKSSKLEHVAYDIRGPVLEEAMRMRANGEKILRLNTGNPA
                     EFGFTAPDEVIHDLIMNARDSEGYSDSKGIFSARKAIMQYCQLKKFPNVDIDDIYLGN
                     GVSELIVMSMQGLLDNGDEVLVPMPDYPLWTAAVSLAGGNAVHYICDEAVEWYPDIDD
                     IKSKITSNTKAIVLINPNNPTGALYPKELLLEIIEIARQNDLIIFADEIYDRMVMDGH
                     VHTPVASLAPDVFCVSMNGLSKSHRIAGFRVGWMVLSGPKTHVKGYIEGLNMLSNMRL
                     CSNVLAQQVVQTSLGGHQSVDELLLPGGRIYEQRNFIYNAIQDIPGLSAVKPKAGLYI
                     FPKIDRNMYRIDDDEQFVLDFLKQEKVLLVHGRGFNWQEPDHFRIVYLPRVDELAQIQ
                     EKMTRFLKQYRR"
     gene            complement(1377..1670)
                     /locus_tag="VQU30_001888"
     CDS             complement(1377..1670)
                     /locus_tag="VQU30_001888"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009014348.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2447938.1"
                     /translation="MMKNSFQKSNFLYYGIILVSVLVKVIMICQLESLVPLLYPSFIG
                     FLVFHVLYHLILFLVAKRSGRWDYLMIWGLFLMFNLLYDSFLGLLFLGLSFGM"
     gene            1832..2284
                     /locus_tag="VQU30_001889"
     CDS             1832..2284
                     /locus_tag="VQU30_001889"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000079155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="universal stress protein"
                     /protein_id="HET2447939.1"
                     /translation="MAQRYQNIMVAIDGSKEADLAFVKGVHSALRNDAKLTIAHVIDT
                     RALQSVSTFDAEVYEELQVDAESLMKEYEKRAKDAGVADVHIVIEMGNPKTLLARTIP
                     DAEEVDLILVGATGLNAFERLLVGSSSEYILRHAKVDLLVVREQEKTL"
     gene            complement(2319..3707)
                     /locus_tag="VQU30_001890"
     CDS             complement(2319..3707)
                     /locus_tag="VQU30_001890"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000453140.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HET2447940.1"
                     /translation="MEVKAVFFDIDGTLVNNRKSVLKSTKDAIKIVKEQGVLVGVATG
                     RGPFFVKELMDDLDLDFAVTYNGQYIFSKDRVLFTSPISKLHLRHLISYAKKEGTEIA
                     LGTKDAMLGSKIMSFGLGSFSQRISRFVPSVLTRTVSQSFNRMVSKVVPQKEEDLLHL
                     MNQPIYQVLMLMTPEESEKAAADFEDLKLTRSNPFASDVINQGNSKLEGIRRVGKEYG
                     FDLNQVMAFGDSDNDLEMLAGVGMSVAMGNGSSSVKEAAKHITTSNQQDGIHKALEHF
                     GVLSSEKVFVSRDYHFNKVKTFHHMMDERTQEEPRAWDLEGATHRAGFKIEELVEFVR
                     AASPSEEDFGQAVSQLHQALDKAAGKVAKKTPAQQDLIGQVDALIDTLYFTYGSFVLM
                     GVDPERIFDIVHQANMGKIFPDGKAHFDPVTHKILKPDNWEEKYAPEPAIKKELQRQL
                     KAYERHKERNKS"
     gene            3773..4735
                     /locus_tag="VQU30_001891"
     CDS             3773..4735
                     /locus_tag="VQU30_001891"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007522433.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="asparaginase"
                     /protein_id="HET2447941.1"
                     /translation="MPKKILVLHTGGTISMQADASGAVVTSSDNPMNHVSNPLEGIQV
                     HALDFFNLPSPHIKPKHMLVLYQKIKEEADNYDGVVITHGTDTLEETAYFLDTMEVPH
                     MPIVLTGAMRSSNELGSDGVYNYLSALRVASDDRAADKGVLVVMNDEIHAAKYVTKTH
                     TTNVSTFQTPTHGPLGLIMKQEILYFKTAEPRVRFDLDHIQGLVPIISAYAGMTDELI
                     DMLDLEHLDGLIIQAFGAGNIPKETAQKLESLLQKGIPVALVSRCFNGIAEPVYAYQG
                     GGVQLQKAGVFFVKELNAQKARLKLLIALNAGLTGQALKDYMEG"
     gene            complement(4732..4923)
                     /locus_tag="VQU30_001892"
     CDS             complement(4732..4923)
                     /locus_tag="VQU30_001892"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2447942.1"
                     /translation="MNTIERTRRLVKGCATHCFEVVDETDEVSSKHVFEVVDRTDEVS
                     NHTYGRATLTWFAEIFEEY"
     gene            complement(4987..5997)
                     /gene="ccpA"
                     /locus_tag="VQU30_001893"
     CDS             complement(4987..5997)
                     /gene="ccpA"
                     /locus_tag="VQU30_001893"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000990602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="catabolite control protein A"
                     /protein_id="HET2447943.1"
                     /translation="MNADDTVTIYDVAREAGVSMATVSRVVNGNKNVKENTRKKVLEV
                     IDRLDYRPNAVARGLASKKTTTVGVVIPNITNGYFSSLAKGIDDIAEMYKYNIVLANS
                     DEDNEKEVSVVNTLFSKQVDGIIYMGYHLTDKIRSEFSRSRTPIVLAGTVDVEHQLPS
                     VNIDYKQATIDAVSYLAKENERIAFVSGPLVDDINGKVRLVGYKETLKKVGITYSEGL
                     VFESKYSYDDGYALAERLISSNATAAVVTGDELAAGVLNGLADKGVSVPEDFEIITSD
                     DSQISRFTRPNLTTIAQPLYDLGAISMRMLTKIMHKEELEEREVLLPHGLTERSSTRK
                     RK"
     gene            complement(6422..7021)
                     /locus_tag="VQU30_001894"
     CDS             complement(6422..7021)
                     /locus_tag="VQU30_001894"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HET2447944.1"
                     /translation="MKVLVAEDQSMLRDAMCQLLTLQPDVESVLQAKNGQEAIQLLEK
                     ESVDIAILDVEMPVKTGLEVLEWIRSERLETKVVVVTTFKRAGYFERAVKAGVDAYVL
                     KERSIADLMQTLHTVLEGRKEYSPELMEVVMTRPNPLTEQEIAVLKGIARGLSNQEIA
                     DQLYLSNGTIRNYVTNILSKLDAGNRTEAANIAKESGWL"
     gene            complement(7022..8119)
                     /locus_tag="VQU30_001895"
     CDS             complement(7022..8119)
                     /locus_tag="VQU30_001895"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001848091.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HET2447945.1"
                     /translation="MLERLKSIHYMFWASLIFMIFPILPVVTGWLSAWHLLIDILFVV
                     AYLGVLTTKSQRLSWLFWGIMLIYVAGNTAFVAVNYIWFFFFLSNLLSYHFSVRSLKS
                     LHVWTFLLAQVLVVGRLLIFQRIEVEFLVYLLGILTFVDLMTLGSVRIRLVEDLKEAQ
                     TKQNTQINLLLAENERNRIGQDLHDSLGHTFAMLSVKTDLALQLFQIQAYPQVEKELR
                     EIQQISKESMREVRTIVENLKSRTLTSELETVKKMLEIAGIEVEIANQLDTASLTQEL
                     ESTASMILLELVTNIIKHAKASKAYLKLERTDQELLLMVRDDGKGFETVTENELHTVR
                     ERVLPFSGEVSVISQKHPTEVQVRLPYKERK"
     gene            complement(8119..8856)
                     /locus_tag="VQU30_001896"
     CDS             complement(8119..8856)
                     /locus_tag="VQU30_001896"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004249339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HET2447946.1"
                     /translation="MKRWIALNKIEFLLTKRQSVYYLLSVGMPTAFYLFFSGMYQDTP
                     GGPANFMRDYLISMTAFSMMSTAIFSFPAVLHTDKMNNWQKTLRHSPVNMVEYYLSKI
                     TSMMVDYLVSILVVFSVGHLVRGVDMSLGSWIGAAFLLIVGSIAFVALGLTLTLLPSS
                     QLMSVVGNLLYLGLAVLGGLWMPISLFPDWMQAIGKCLPTYQLMELLKTFLNEGSINL
                     SATVYLLVFSAVLFGLTIYLQGHKENA"
     gene            complement(8858..9742)
                     /locus_tag="VQU30_001897"
     CDS             complement(8858..9742)
                     /locus_tag="VQU30_001897"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000219360.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET2447947.1"
                     /translation="MNMIKVQGLHKNIKSKAILKDISFEVAEGECVALIGPNGAGKTT
                     LLDCLLGDKLVTSGQVYIQDLPVTSSKLDYTRSYLPQENVIVQKLKVKELIAFFQRIY
                     PNPLNNQEIDQLLQFDQQQKEQFAEKLSGGQKRLLSFILTLIGRPKLVFLDEPTAAMD
                     TSTRQRFWEIVRDLKAQGVTILYSSHYIEEVEHTADRILVLNKGELIRDTTPLAMRSE
                     EIEKHFILPLAYKEVVEKSVLVENWVQKQDALQVVTCEADAFWELLVQAGCRIQEIEV
                     NNRSLLDTIFEETQKGDD"
     gene            complement(9729..9923)
                     /locus_tag="VQU30_001898"
     CDS             complement(9729..9923)
                     /locus_tag="VQU30_001898"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000750983.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2447948.1"
                     /translation="MKKAILFLFIGLSLVVWLVEMFTGWFDQSFLHQVIRGAWGLGFM
                     ISVVFPMGMEWLKGEYYEHD"
     gene            complement(9920..10126)
                     /locus_tag="VQU30_001899"
     CDS             complement(9920..10126)
                     /locus_tag="VQU30_001899"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000503440.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2447949.1"
                     /translation="MEEEEMRNKMIIAVSLVVAGVMTYLMFSGLDEGFYHFPWELFAS
                     FGIMSWLIREGLKLVRDVKKELEK"
BASE COUNT         3213 a         2412 c         1931 g         3048 t
ORIGIN      
        1 caagccctat ctacgatact gtttcaagaa acgagtcatc ttttcttgga tttgggctaa
       61 ctcatcaaca cgaggaaggt aaacgatacg gaagtggtct ggttcctgcc agttaaagcc
      121 tcgaccatga accaagagaa ccttttcctg cttcaagaaa tcaaggacaa actgctcatc
      181 atcatcgata cggtacatat tgcggtcgat ttttgggaag atatagagcc ccgccttggg
      241 tttaacggca gacaaacctg gaatatcttg aatggcatta tagatgaaat ttctttgctc
      301 gtagattcgt ccaccaggaa gaagcaattc atcgactgat tggtgacccc ccaaggaagt
      361 ttgtacgact tgttgggcca aaacgttaga gcaaaggcgc atattggaca gcatattgag
      421 cccttcgata tagcccttaa catgagtctt agggccagac aagaccatcc aacccacacg
      481 gaaacctgct atgcggtggg attttgacag accattcatg ctgacacaga agacatctgg
      541 tgccaagctc gccacaggcg tatgcacatg tccgtccatt accatgcggt catagatttc
      601 atccgcaaag ataatcaaat cgttttgacg ggcaatctca ataatctcca gcaagagttc
      661 cttaggataa agggctccag ttgggttatt tggattgata aggacaattg ccttggtatt
      721 ggaagtgatt tttgacttga tatcgtcaat atctgggtac cattccacag cttcatcaca
      781 gatatagtga acggcatttc ctccagctag gctgacagcc gccgtccata gaggatagtc
      841 tggcattggc actaagacct catccccatt gtccaaaagc ccctgcatgg acatgacaat
      901 caactcactg acaccatttc caaggtaaat atcatcaata tctacgtttg ggaatttctt
      961 cagctggcaa tactgcatga tggccttacg ggctgagaaa atccctttgg agtcagaata
     1021 gccttcacta tcacgcgcat tcataatcaa gtcatgaatg acctcgtctg gcgctgtaaa
     1081 gccaaattct gctggatttc ctgtattcag acgtaaaatc ttttctccat tcgctcgcat
     1141 ccgcatggct tcttccaata caggaccacg gatatcataa gcaacatgct ctaacttact
     1201 agacttgtta tattctttca tcttgtttcc tcaattcatc aggatagtaa cattatacca
     1261 ctagaaagag aatgcgacaa gtttactgaa atgtgttact agtttcgtat agaagaaaaa
     1321 ccttgctaaa ggcgaggtta agaacgtaga gatagcaggc attttgcaaa gacacatcac
     1381 ataccaaaag ataaacctag aaaaagcaag cctagaaagg agtcataaag aagattaaac
     1441 atgaggaaaa gcccccatat catcaagtaa tcccaacgcc cacttcgttt tgcaactaga
     1501 aataagatta gatggtagag tacatgaaag actaaaaatc caataaaact tggataaaga
     1561 agcggtacca gactctctaa ttgacagatc atgatcactt ttaccaagac tgaaactagg
     1621 ataattccat aatacaggaa atttgatttt tgaaaagagt ttttcatcat tctcccttcc
     1681 ttcacttctt tccttctatc ctttctttta ttttatcata tatttatata gattttaagc
     1741 cctaatattc ttttgaaaaa tacttttttt gctttacttc tatagtgaaa aggtttacaa
     1801 ttatagtaag aaaatttcag gaggtttcat tatggcacaa cgttaccaaa atatcatggt
     1861 cgcaatcgat ggttctaagg aagcggactt ggcttttgtc aagggagttc attctgctct
     1921 acgaaacgac gctaaactca ccatcgcaca tgtcattgac acacgcgctc tccaaagcgt
     1981 atccaccttt gatgctgaag tttacgaaga actccaagtc gacgctgaaa gtctgatgaa
     2041 agagtacgaa aaacgtgcta aagatgctgg ggtagcagat gttcatatcg tcattgaaat
     2101 gggaaatcca aagaccctgc tagcacgtac tattccagat gccgaggaag tggacctcat
     2161 cctcgttggc gcaactggtc tcaacgcctt tgaacgcctc ttggtcggct cttcatctga
     2221 atacatactc cgccatgcta aggtcgattt gctggttgtg agagaacaag aaaaaacctt
     2281 ataatcacaa agaaaaggag cccctagctc ctttttgttt acgatttatt tctctcttta
     2341 tggcgttcgt aagccttgag ctggcgctgc agttcctttt taatagcagg ttctggagca
     2401 tatttttctt cccaattatc tggttttaag attttatggg tcactggatc aaaatgagcc
     2461 ttgccatctg gaaaaatttt ccccatattg gcctgatgga caatatcaaa aatacgttct
     2521 gggtccaccc ccatcaagac aaaactgccg taggtgaagt aaagcgtgtc aatcaaggca
     2581 tccacttgcc ctatcaaatc ttgctgagca ggtgtcttct tggctacttt acctgctgcc
     2641 ttatcaaggg cctgatgaag ttgcgataca gcttgaccaa aatcttcttc agaaggactg
     2701 gctgctcgaa caaactccac caattcttct attttaaaac cagccctatg ggttgcaccc
     2761 tctaaatccc aagctcgagg ttcttcttgg gttcgttcat ccatcatgtg gtggaaggtc
     2821 ttgaccttat tgaaatgata gtcacggctg acaaagactt tttctgaaga caaaacacca
     2881 aaatgttcca aggccttgtg gatcccatct tgttgattgc tagtggtaat gtgcttggca
     2941 gcttccttga cactgctact accatttccc atagcgaccg acataccgac gccagccagc
     3001 atttcaaggt cattatctga gtcaccaaaa gccatgactt ggttgaggtc aaagccatat
     3061 tctttcccaa ctcggcgaat gccttctaat ttagaatttc cctgattgat gacatccgat
     3121 gcaaaaggat tgctacgtgt caatttcaag tcttcaaaat cagctgccgc cttctcagat
     3181 tcttctggtg tcatcagcat caaaacttgg tagataggct gattcatcag gtgaagcagg
     3241 tcctcttcct tttggggaac aaccttgctg accatgcgat taaaagactg actcaccgtc
     3301 cgagttaaaa cagagggaac gaagcgacta attcgttggg aaaaagaacc cagaccaaag
     3361 gacatgattt tagaacccaa catggcatcc ttggtcccta gggcaatctc cgtgccctct
     3421 tttttagcat agctaattag atggcgcaaa tgtaacttgg aaatagggct cgtgaacaag
     3481 actctgtctt tactaaagat atactggcca ttataggtta ccgcaaaatc cagatccaaa
     3541 tcgtccatca attccttaac aaaaaaaggt cctcgccctg tcgctacgcc aactagtacc
     3601 ccttgttctt tgacaatctt aatcgcgtcc ttagtggatt tcaaaacact cttgcgattg
     3661 ttgaccaagg ttccatcgat atcaaaaaaa acagctttga cttccatcct attccaatct
     3721 ccccttttgt gatacaatga ttataccaca tttcagaaag agtgagtaaa tcatgcctaa
     3781 gaaaatcctt gttttacata cgggtggaac tatttccatg caggccgatg cttctggcgc
     3841 tgttgtgacg agttcagata atcccatgaa ccatgtgtcc aacccacttg aaggaatcca
     3901 agtccacgcc ttggactttt ttaaccttcc aagtccccat atcaaaccca aacatatgct
     3961 ggtcctctac cagaaaatta aagaggaagc agataactac gatggagtgg taatcacaca
     4021 cggaaccgat actttagagg aaacagccta tttccttgat accatggaag ttccccatat
     4081 gcctatcgtt ctaacaggag ccatgcgtag ctccaatgag ctcggtagtg atggtgttta
     4141 taattaccta agtgctttac gagtggccag cgatgacagg gctgctgaca aaggagtttt
     4201 ggtcgttatg aacgatgaaa tccacgctgc caagtatgtc accaaaacac atacgactaa
     4261 tgtcagcacc ttccagactc caacacatgg ccccctcggt ctcatcatga aacaggaaat
     4321 cctctacttc aaaacagctg aacctcgtgt tcgctttgac cttgatcaca tacaaggttt
     4381 agtccctatc atctcggctt atgctggtat gacagatgag ctgattgata tgctggattt
     4441 agaacacttg gacggtttga ttatccaagc cttcggagct ggtaatattc ccaaagaaac
     4501 ggctcaaaaa ttagaaagcc ttctgcaaaa aggaatccca gtcgctctgg tatcacgatg
     4561 ctttaacggt attgccgagc ctgtttatgc ctaccagggt gggggcgtac agttgcaaaa
     4621 agcaggcgtt ttctttgtta aagaactcaa cgcccaaaaa gctcgcttga aactcctcat
     4681 cgccctcaat gccggactaa caggacaggc tttgaaagac tatatggaag gctaatactc
     4741 ttcgaaaatc tctgcaaacc acgtcagagt cgccctaccg tatgtatggt tactgacttc
     4801 gtcagttcta tctacaacct caaaaacatg ttttgagctg acttcgtcag tttcatctac
     4861 aacctcaaaa cagtgtgttg cgcagccttt aaccagccgc ctagtccgct ctatggtatt
     4921 cattaagtca acatctcttg tttaagagca caaaatcagg aaatcttctc gattccctga
     4981 ttttttctat ttacgttttc gtgttgagct acgttctgtc aaaccatgag gtaagagaac
     5041 ttcacgttct tccaactctt ccttatgcat aatcttggtc aacatacgca tactaatggc
     5101 accaaggtca taaagaggtt gggcaatcgt tgtcaagttt ggacgggtaa agcgtgagat
     5161 ttgtgaatca tcactagtaa taatttcaaa atcttctggc acagaaacac ccttatcagc
     5221 caaaccgttc aagactcctg ctgccaactc atcacctgtc acaactgctg cagttgcatt
     5281 tgatgaaatc aaacgctctg ctaaggcgta accatcatca tagctatatt tagattcaaa
     5341 taccaaaccc tcactataag tgattcctac ttttttcaag gtttccttgt agccaactaa
     5401 acgaacctta ccattgatgt catccactag cggaccgcta acgaaagcaa tacgctcatt
     5461 ttctttagca aggtagctca ctgcatcaat tgttgcttgc ttatagtcaa tattgacact
     5521 tggcaactgg tgctcaacat cgacagttcc tgcgagaaca atcggagtac gtgaacgcga
     5581 aaattctgag cgaattttat ctgtcaagtg ataacccata tagataatgc catctacctg
     5641 ctttgaaaag agggtattga caacagaaac ttctttctcg ttatcttcat cgctattagc
     5701 taggacaata ttgtacttgt acatttctgc aatatcatca atccccttag ccaaactcga
     5761 aaaataacca ttggtaatat ttggaatcac gacaccgaca gtggttgtct ttttacttgc
     5821 aagaccacgc gcaactgcat ttggacgata atccaaacga tcaattacct ctagcacttt
     5881 tttacgggta ttctctttta catttttatt gccattgacc acacggctga ccgtcgccat
     5941 ggaaacacct gcttcacgag cgacatcata aatggttact gtatcatctg cattcattcc
     6001 ttttcctgtc ctttctatct cacacattct tttacaagta gaggtactga ttgaagctct
     6061 atatctactt acaaaagtga agatgtgaaa atttcgtttt catatttcta cttattccat
     6121 tctatcacta attgtaaaca ctttcaagtg ttttttgaag attgattgaa aaaatttcat
     6181 agaaaaccta ggtttagctc cttgctacca ccttagacta aataaaaagg aggaaactaa
     6241 gcccttctaa agttatagta aaatgaaata agaacaggat aaatcgatca ggacagtcaa
     6301 atcgatttct aacaatgttt tagaagtaga ggtgtactat tctagtttca atctactata
     6361 ggtattgttc cattcactac cgtcaatttt agcacatagt cttcatgaaa atattatatc
     6421 atcataacca accagattct tttgcgatat tagctgcctc tgttcgatta ccagcatcca
     6481 gttttgaaag aatattggtg acatagtttc gaatagttcc gtttgagagg taaagctgat
     6541 ctgcgatttc ttggttggat aagccccggg cgattccctt taagacagca atctcttgtt
     6601 ctgtcaacgg attgggacgg gtcatcacca cttccatcaa ttcaggcgaa tactccttgc
     6661 gtccttcgag gacggtgtgc aaggtttgca tgaggtctgc aatgcttcgt tcctttaata
     6721 cataagcatc cactccagcc ttgaccgcac gttcaaaata cccagcacgc ttgaaggtcg
     6781 tcaccacaac cacctttgtt tcaagccttt ctgatcgtat ccactccaag acttcaagac
     6841 ctgtcttaac aggcatttct acgtcaagga tggcgatatc tacagactcc ttttctaata
     6901 gttggattgc ttcttgccca ttcttggctt gaaggacaga ctccacatct ggttgaagcg
     6961 tgagcaattg acacatagca tctcgcaaca tactttgatc ttctgcgact aatactttca
     7021 tctactttct ctccttataa ggtagtcgaa cttgcacttc cgttggatgt ttctgactga
     7081 ttacacttac ttctcctgaa aatggaagga cacgttctcg aactgtatgg agctcatttt
     7141 ctgttacagt ttcaaaacct ttcccgtcat ctctgaccat caggagcaat tcctgatctg
     7201 tgcgttctaa ttttaagtag gctttagacg ctttagcatg tttgatgatg ttggtcacta
     7261 attcaagcaa aatcatggaa gccgttgact ctaattcctg agttaagcta gctgtatcta
     7321 gttgattagc tatttccacc tcaattccag caatttctaa catctttttc acagtctcta
     7381 gttcggatgt caaagttcta gacttaagat tttccacaat ggttcgcact tcacgcattg
     7441 attctttgct aatctgctgt atttctctta attccttttc cacttgtgga taagcctgta
     7501 tttgaaataa ctgcaaggct agatcagttt taacactaag catagcaaag gtatgcccca
     7561 gactatcatg caaatcttga ccgatacgat tgcgctcatt ttctgctagc aatagattta
     7621 tctgggtatt ttgcttagtc tgagcttctt tcaaatcctc gacaaggcga attcgaaccg
     7681 agcccaaagt catcaaatca acaaaagtaa gaattccaag cagatagact agaaactcaa
     7741 cttcgattct ctgaaaaatc aaaagtcgcc ccacaacaag gacttgagca agaagaaaag
     7801 tccagacatg taaagacttt aaactacgta cgctgaaatg ataacttaag agattggaaa
     7861 ggaaaaagaa aaaccagata taattcacag caacaaaggc ggtattccca gctacataga
     7921 tcagcatgat cccccagaaa agccaagata ggcgctggct cttagttgtt aaaacaccca
     7981 aatatgccac tacaaataga atatcaatca ataaatgcca ggcagaaagc cacccagtca
     8041 ctacaggtag gatggggaaa atcataaaaa ttaaactggc ccaaaacata tagtgtatgc
     8101 ttttcagtct ttcaagcatt aagcattctc cttatgacct tgaaggtaaa tggtcaaacc
     8161 aaacaaaact gctgaaaaaa caagtagata aactgtggct gatagattga tgctaccctc
     8221 gtttaagaag gtcttgagca actccatcaa ctgataagtt ggtaggcact tcccgattgc
     8281 ttgcatccag tctggaaata aagagatggg catccagagt ccacctaaaa cagccaagcc
     8341 tagatagaga agattgccca cgacagacat cagctgacta gaaggcaaga gtgtcaaggt
     8401 caagccaagc gctacaaaag ctatacttcc tactatcagc aagaacgcag ccccaatcca
     8461 gcttcctaaa gacatatcca cacctctgac caagtgccca actgagaaaa caaccaggat
     8521 tgagaccaaa taatcaacca tcatacttgt tatctttgat agataatatt ctaccatatt
     8581 tacagggcta tgacgcaatg ttttctgcca gttgttcatc ttatcggtat gtaagacagc
     8641 tgggaatgaa aagatagcgg tcgacatcat ggaaaaggca gtcatggaga tgaggtagtc
     8701 gcgcataaaa ttagccggtc cacctggtgt gtcctggtac atgcctgaaa agaatagata
     8761 gaaggctgtc ggcatcccta cagataataa ataatagact gattgccgtt tggtcaatag
     8821 aaattctatc ttgtttagtg caatccatcg tttcatctta gtcatctccc ttctgtgttt
     8881 cttcaaagat tgtatccaac aaactacgat tattgacttc gatttcttgt atcctacatc
     8941 ctgcttgaac taacagttcc cagaaagcat ccgcttcgca tgtgactact tgtaaggcat
     9001 cttgtttttg tacccagttt tcaaccaaga ctgacttctc aacgacttcc ttgtaagcta
     9061 gcggaaggat aaaatgcttt tcaatctcct cactacgcat agctagaggc gtcgtgtcac
     9121 gaatcaactc tcccttattt aaaaccaaaa tccggtcagc tgtatgctct acctcttcaa
     9181 tataatgaga cgaatagaga atggtgactc cttgcgcttt taggtcccga acaatttccc
     9241 aaaaacgttg acgagttgaa gtatccatgg cagcagttgg ctcatctaaa aagacaagct
     9301 ttggtcgccc aattaaggtc aagataaaag ataaaagacg cttttgccca cctgacaatt
     9361 tttctgcgaa ttgctctttc tgttgctggt caaactgtaa tagttgatcg atttcctggt
     9421 tgttcaaggg atttggatag atacgttgaa agaaagcaat caactcttta acctttagtt
     9481 tttgaacaat tacattttct tgagggagat aggatctcgt atagtctaac ttagagctcg
     9541 ttaccggcaa atcttggata tatacttgcc cactggtgac caatttatct ccaagcaaac
     9601 agtccaagag tgtcgtctta ccagctccat ttggcccaat caaggcgacg cattcacctt
     9661 cagctacctc aaaggaaata tccttcaaaa tagccttact tttgatgttt ttatgtaagc
     9721 cttgtacctt aatcatgttc ataatattct cctttcaacc actccattcc catagggaaa
     9781 acgacggaaa tcataaatcc taatccccag gcgccgcgaa taacttggtg aagaaaggat
     9841 tgatcaaacc aacctgtaaa catttctacc aaccatacca ctagtgatag tccaataaaa
     9901 agaaagagaa tcgctttttt catttttcaa gctccttttt cacatctctt actaatttca
     9961 agccttctcg tatcaaccaa gacatgattc caaagcttgc aaacaactcc caaggaaaat
    10021 gatagaatcc ttcgtccaat cctgagaaca tgagataagt catgactcct gctactacta
    10081 aactcactgc gataatcatt ttatttctca tctcttcttc ctccatttca tactacaatt
    10141 atagtctttt gaaatcagag gagatagaag cttctgtcac taaaaaatat gacaaatgtc
    10201 ataaaaaatt ctgttcaaaa caagcaagat acactataca ataaaacaca attagataaa
    10261 tctaaggcaa cttcctcaaa agagatatca aaccccattc acactataat gtaaactaat
    10321 acttatttaa agtcaaaaga gcggaaattt ttatcgtaca aacatatata ttataggtaa
    10381 gacaaaaaac tcttcaatta ctttcttaaa aatttatagg agttataaaa tctattaaat
    10441 ttcaatgtgg atacctaaac tacagtattt attgaaaaga ctggagacaa aaagtatacg
    10501 ctgccaaaat gaattgctga aaatcaaaaa agagagaagc aaactgattc tctcttaatg
    10561 tatataatat ctagttataa aaatacacac tcacatatct ctgt
//
LOCUS       DAVBBO010000067        10313 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ST1
            SAMEA2066453-rid20184263.denovo.067, whole genome shotgun sequence.
ACCESSION   DAVBBO010000067 DAVBBO010000000
VERSION     DAVBBO010000067.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2066453
            Sequence Read Archive: ERR351777
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 10313)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10313)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980402.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980402.1
            Genome Coverage       :: 176x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:17:33
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,141
            CDSs (total)                      :: 2,104
            Genes (coding)                    :: 1,953
            CDSs (with protein)               :: 1,953
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 16S)
            partial rRNAs                     :: 1 (23S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 151
            CDSs (without protein)            :: 151
            Pseudo Genes (ambiguous residues) :: 0 of 151
            Pseudo Genes (frameshifted)       :: 73 of 151
            Pseudo Genes (incomplete)         :: 76 of 151
            Pseudo Genes (internal stop)      :: 40 of 151
            Pseudo Genes (multiple problems)  :: 32 of 151
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10313
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2066453-rid20184263.denovo.067"
                     /strain="ST1"
                     /db_xref="taxon:1313"
     gene            <1..121
                     /locus_tag="VQU30_001900"
     CDS             <1..121
                     /locus_tag="VQU30_001900"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000458116.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2447950.1"
                     /translation="ASQWFKVSDKWYYVNGSGALAVNTTVDSYRVNANGEWVN"
     gene            complement(351..1331)
                     /gene="dusB"
                     /locus_tag="VQU30_001901"
     CDS             complement(351..1331)
                     /gene="dusB"
                     /locus_tag="VQU30_001901"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA dihydrouridine synthase DusB"
                     /protein_id="HET2447951.1"
                     /translation="MTNLNTPFMIGNIEIPNRTVLAPMAGVTNSAFRTIAKELGAGLV
                     VMEMVSDKGIQYNNEKTLHMLHIDEGENPVSIQLFGSDEDSLARAAEFIQENTKTDIV
                     DINMGCPVNKIVKNEAGAMWLKDPDKIYSIINKVQSVLDIPLTVKMRTGWADPSLAVE
                     NALAAEAAGVSALAMHGRTREQMYTGHADLETLYKVAQALTKIPFIANGDIRTVQEAK
                     QRIEEVGADAVMIGRAAMGNPYLFNQINHYFETGEILPDLTFEDKMKIAYEHLKRLIN
                     LKGENVAVREFRGLAPHYLRGTSGAAKLRGAISQASTLAEIEALLQLEKA"
     gene            complement(1318..2190)
                     /gene="hslO"
                     /locus_tag="VQU30_001902"
     CDS             complement(1318..2190)
                     /gene="hslO"
                     /locus_tag="VQU30_001902"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000357853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Hsp33 family molecular chaperone HslO"
                     /protein_id="HET2447952.1"
                     /translation="MDKIIKTISESGAFRAFVLDSTETVRTAQERHQTQASSTVALGR
                     TLIASQILAANEKGNTKLTVKVLGSSSLGAIITVADTKGNVKGYVQNPGVDIKKTATG
                     EVLVGPFVGNGQFLVITDYGAGNPYNSITPLISGEIGEDLAFYLTESQQTPSAVGLNV
                     LLDEEDKVKVAGGFLVQVLPGAKKEEIARFEKRIQEMPAISTLLESDDHIEALLKAIY
                     GDEAYKRLSEEEIRFQCDCSHERFMNALASLPSSDLQEMKEEDHGAEITCQFCQTTYN
                     FDEKDLEELIRDKS"
     gene            2355..3782
                     /locus_tag="VQU30_001903"
     CDS             2355..3782
                     /locus_tag="VQU30_001903"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000280545.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HET2447953.1"
                     /translation="MYLGDLMEKAECGQFSILSFLLQESQTTVKAVMEETGFSKATLT
                     KYVTLLNDKALDSGLELTIHSEDENLRLSIGAATKGRDIRSLFLDSAVKYQILVYLLY
                     HQQFLAHQLAQELVISEATLGRHLAGLNQILSEFDLSIQNGRWRGPEHQIRYFYFCLF
                     RKVWSSQEWEGHMQKPERKQEIANLEEICGASLSAGQKLDLVLWAHISQQRLRVNACQ
                     FQVIEEKMRGYFDNIFYLRLLRKVPSFFAGQHIPLGVEDGEMMIFFSFLLSHRILPLH
                     TMEYILGFGGQLADLLTQLIQEMKKEELLGDYTEDHVTYELSQLCAQVYLYKGYILQD
                     RYKYQLENRHPYLLMEHDFKETAEEIFHALPAFQQGTDLDKKILWEWLQLIEYMAENG
                     GQHMRIGLDLTSGFLVFSRMAAILKRYLEYNRFITIEAYDPSRHYDLLVTNNPIHKKE
                     QTPVYYLKNDLDMEDLAGIRQLLFT"
     gene            3941..5449
                     /gene="glpK"
                     /locus_tag="VQU30_001904"
     CDS             3941..5449
                     /gene="glpK"
                     /locus_tag="VQU30_001904"
                     /EC_number="2.7.1.30"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000076796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol kinase GlpK"
                     /protein_id="HET2447954.1"
                     /translation="MSQEKYIMAIDQGTTSSRAIIFNKKGEKVSSSQKEFTQIFPQAG
                     WVEHNANEIWNSVQSVIAGAFIESGVKPNQIEAIGITNQRETTVVWDKKTGLPIYNAI
                     VWQSRQTAPLAEQLKSQGYVEKFHEKTGLIIDAYFSATKVRWILDHVEGAQERAEKGE
                     LLFGTIDTWLVWKLTDGAAHVTDYSNAARTMLYNIKELKWDDEILEILNIPKAILPEV
                     RSNSEIYGKTAPFHFYGGEVPISGMAGDQQAALFGQLAFEPGMVKNTYGTGSFIIMNT
                     GEEMQLSENNLLTTIGYGINGKVYYALEGSIFIAGSAIQWLRDGLRMVENSPESEKYA
                     RDSHNNDEVYVVPAFTGLGAPYWNQNARGSVFGLTRGTSKEDFIKATLQSIAYQVRDI
                     IDTMQVDTQTAIQVLKVDGGAAMNNFLMQFQADILGIDIARAKNLETTALGAAFLAGL
                     SVGYWKDLDELKLLNETGELFEPSMNESRKEQLYKGWKKAVKATQVFAEVDD"
     gene            5491..7317
                     /gene="glpO"
                     /locus_tag="VQU30_001905"
     CDS             5491..7317
                     /gene="glpO"
                     /locus_tag="VQU30_001905"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001865074.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 1 glycerol-3-phosphate oxidase"
                     /protein_id="HET2447955.1"
                     /translation="MEFSKKTRELSIKKMQERTLDLLIIGGGITGAGVALQAAASGLE
                     TGLIEMQDFAEGTSSRSTKLVHGGLRYLKQFDVEVVSDTVSERAVVQQIAPHIPKPDP
                     MLLPVYDEDGATFSLFRLKVAMDLYDLLAGVSNTPTANKVLSKDQVLERQPNLKKEGL
                     VGGGVYLDFRNNDARLVIENIKRANQDGALIANHVKAEGFLFDESGKITGVVARDLLT
                     DQVFEIKARLVINTTGPWSDKVRNLSNKGTQFSQMRPTKGVHLVVDSSKIKVSQPVYF
                     DTGLGDGRMVFVLPRENKTYFGTTDTDYTGDLEHPKVTQEDVDYLLGIVNNRFPESNI
                     TIDDIESSWAGLRPLIAGNSASDYNGGNNGTISDESFDNLIATVESYLSKEKTREDVE
                     SAVSKLESSTSEKHLDPSAVSRGSSLDRDDNGLLTLAGGKITDYRKMAEGAMERVVDI
                     LKAEFDRSFKLINSKTYPVSGGELNPANVDSEIEAFAQLGVSRGLDSKEAHYLANLYG
                     SNAPKVFALAHSLEQAPGLSLADTLSLHYAMRNELALSPVDFLLRRTNHMLFMRDSLD
                     SIVEPILDEMGRFYDWTEEEKATYRADVEAALANNDLAELKN"
     gene            7387..8091
                     /locus_tag="VQU30_001906"
     CDS             7387..8091
                     /locus_tag="VQU30_001906"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004262009.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aquaporin family protein"
                     /protein_id="HET2447956.1"
                     /translation="MMNELFGEFLGTLILILLGNGVVAGVVLPKTKSNSSGWIVITMG
                     WGIAVAVAVFVSGKLSPAHLNPAVTIGVALKGGLPWASVLPYILAQFAGAMLGQILVW
                     LQFKPHYEAEENAGNILATFSTGPAIKDTVSNLISEILGTFVLVLTIFALGLYDFQAG
                     IGTFAVGTLIVGIGLSLGGTTGYALNPARDLGPRIMHSILPIPNKGDGDWSYAWIPVV
                     GPVIGAALAVLVFSLF"
     gene            8388..8591
                     /locus_tag="VQU30_001907"
     CDS             8388..8591
                     /locus_tag="VQU30_001907"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2447957.1"
                     /translation="MPKWSNPDYVNELDPKIVDMLVEFHKSQGTLETPEAQAEIAQKR
                     EEIEQRRAELEDKKQELLNRLNK"
     gene            complement(8678..9265)
                     /locus_tag="VQU30_001908"
     CDS             complement(8678..9265)
                     /locus_tag="VQU30_001908"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001808792.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2447958.1"
                     /translation="MFVFADDSLSANSKVVSGEAQFENGSSVRFGDTQVNILSDEVLE
                     VVNPDGSVDTIERRADGVYINGAFYMAYQKNEIDLNISFRSYDPNVWNYVNTIHGNKQ
                     ANTFANFMTGAGISYMIGRIGTLLGGPWGAIIGGAYFGIQAYQSYLDSQSPYPYYITS
                     TYIHVAQKKWKFITEYYRNSNYTGYVKTVTTYVNF"
BASE COUNT         3000 a         2041 c         2355 g         2917 t
ORIGIN      
        1 agcaagccaa tggttcaaag tatcagataa atggtactat gtcaatggct caggtgccct
       61 tgcagtcaac acaactgtag atagctatag agtcaatgcc aatggtgaat gggtaaacta
      121 aacctaatat aactagttaa tactgacttc ctgtaagaac tctttaaagt attccctaca
      181 aataccatat cctttcagta gataatatac ccttgtagga agtttagata aaaaaataac
      241 tctgtaatct ctagccggat ttatagcgct agagactacg gagttttttt gatgaggaaa
      301 gaatggcggc attcaagagg ctctttaaga gagttacggg ttttaaacta ttaagccttc
      361 tccaattgca agagggcttc aatctctgcc agggtgctag cttgcgaaat ggctccacgg
      421 agtttggcag cgccagatgt tccacggaga tagtgaggag cgaggccgcg gaattcacga
      481 actgcgacgt tttctccttt gaggttaatc aatcgtttca agtgttcgta ggcgatcttc
      541 atcttgtctt caaaggtcaa atcaggtagg atttctcctg tttcaaagta atggttgatt
      601 tggttgaaga ggtaaggatt tcccatggca gctcggccaa tcatgactgc gtcagcacca
      661 acttcttcga tgcgttgctt ggcttcttgg acagtacgga tatcaccgtt ggcgatgaat
      721 ggaatcttgg ttagagcttg ggcaaccttg taaagggtct caaggtctgc gtggccagta
      781 tacatttgtt cacgggtacg gccatgcatg gcgagggcag aaacacctgc agcctcagca
      841 gcgagggcat tttctactgc aagagatggg tccgcccatc cggtacgcat tttgacagta
      901 agtgggatat caaggacaga ctggaccttg ttgatgatag agtagatctt gtcaggatcc
      961 ttgagccaca tagctccagc ttcgttcttc acgattttgt tgacagggca gcccatgttg
     1021 atatcgacga tatcggtctt ggtgttttct tggatgaatt ctgctgcgcg tgctaggctg
     1081 tcttcatcgc taccaaaaag ttggatagag acagggtttt cgccctcatc gatatgaagc
     1141 atgtgcaggg ttttttcgtt gttgtattgg attcccttgt cagagaccat ttccattaca
     1201 acgagtccag ctccgagctc ttttgcgatg gtacgaaagg ctgagttggt cacgccagcc
     1261 ataggcgcta aaacggtacg attgggaatc tcaatattgc caatcataaa aggtgtatta
     1321 agatttgtca cgaatgagtt cctccaggtc cttttcatca aagttgtaag tagtttggca
     1381 gaattgacaa gtgatttctg ccccgtggtc ttcctctttc atttcctgta agtctgagct
     1441 tggaaggctg gcaagagcgt tcataaagcg ttcatggcta cagtcacatt ggaaacggat
     1501 ttcttcttca gaaagacgct tgtaggcttc gtccccgtag atagccttga ggagggcttc
     1561 gatatggtcg tcgctttcga gaagagtaga gatagctggc atttcttgga tgcgtttttc
     1621 aaagcgagca atctcttctt tcttggctcc tggcaagact tgaactagga aaccacctgc
     1681 aaccttgacc ttgtcttcct cgtccaaaag gacattgagg ccgaccgctg aaggcgtttg
     1741 ttggctttca gtaaggtaaa aggcaaggtc ttcaccgatt tctccagaga tgaggggagt
     1801 tatagagttg taaggatttc cagcaccgta gtctgtgata acgaggaatt gaccatttcc
     1861 aacaaaaggt ccgactagga cttcaccagt cgcagtcttt ttgatgtcaa caccaggatt
     1921 ttgaacatag cctttgacgt tccccttggt atcagcgacg gtgataatag cacctagaga
     1981 gctagagccc aacaccttaa ctgtaagttt ggtatttcct ttttcattgg ctgcgagaat
     2041 ctggctagcg ataagagttc gaccaagcgc tacagttgag ctagcttggg tttgatgtct
     2101 ttcttgagca gtgcggacgg tttccgtgct atcaaggaca aaagcacgaa aggctccgct
     2161 ttctgatata gttttaataa ttttatccat agctactatt ttagcataaa aatgcccaaa
     2221 gggggagccg tgtgtttact gattttcagg ataatggacc aggaaatcag catgaaaata
     2281 aaaagagaaa cagattattt cagcatttgt aagatttatg ctatgcttaa ggtagaaaat
     2341 gaaaggggta acaaatgtat ttaggagatt tgatggagaa agccgagtgt ggtcaatttt
     2401 caatcctttc ctttctatta caagagtctc agacgaccgt caaggctgta atggaagaaa
     2461 caggattttc aaaagcaacc ctaaccaaat atgtcaccct gctcaatgac aaggctttgg
     2521 atagtggctt agaactgact attcactcag aagatgaaaa tctgcgtctg tctatcggtg
     2581 cagctaccaa ggggagagat attcggagct tgtttttgga tagtgctgtt aaataccaga
     2641 ttttggttta tcttctctac caccaacagt ttttagccca tcagctggct caagaattgg
     2701 tgattagcga ggctacgctt ggtcgtcact tggctggttt aaatcagatt ttgtcagaat
     2761 ttgatttatc catccaaaat ggacgctgga gaggtccaga gcatcagatt cgctatttct
     2821 atttctgtct tttccgaaag gtctggtcga gtcaggaatg ggaaggtcac atgcagaaac
     2881 cagagagaaa acaggagatt gccaatttag aggaaatctg cggtgcaagt ttgtctgcgg
     2941 ggcagaaatt ggacttggtt ctctgggctc acatcagtca acaacgtctt cgggtcaatg
     3001 cttgtcagtt tcaagtcata gaagagaaaa tgcgagggta ttttgacaat atcttttatc
     3061 ttcgtttgct gagaaaggtt ccgtcctttt ttgctgggca acatattcca ctaggagttg
     3121 aggatggtga gatgatgata ttcttctctt ttctcctatc tcatcgcatt cttcctcttc
     3181 atactatgga gtatattctt ggttttggag ggcagttggc agatttactg acgcaattga
     3241 ttcaagaaat gaagaaggag gaactattgg gggattatac agaggaccat gtcacctatg
     3301 aactcagtca gctttgtgct caagtctatc tctataaggg ctatatttta caggatcgct
     3361 acaagtacca gttagagaat cgtcatccat atttactgat ggaacatgat tttaaagaga
     3421 cagcagagga gatttttcat gctctacctg cttttcaaca ggggacagat ttagataaga
     3481 agattctctg ggaatggctc cagttaatcg aatatatggc tgaaaacggt ggccagcata
     3541 tgcggattgg tctggatttg acatctggtt ttcttgtctt ttcaaggatg gcagccattt
     3601 tgaaacggta tttggaatac aatcgtttta ttaccattga agcttatgac cctagtcggc
     3661 attatgattt gctggttacc aataacccga ttcataagaa ggaacagaca ccagtctatt
     3721 atttaaaaaa cgacttggat atggaagatt tggcagggat tcgtcagtta ttattcactt
     3781 aaaaggcttg gttaatctag gtcttttttg tgaaattcac acaatctcct cacatttttt
     3841 taaaaattaa aaaaagttga taaacaagaa agcgctttat tttgtatact agtaagtgta
     3901 aagaggaaac acctcaagat ctttatcagg aggacagtac atgtcacaag aaaaatacat
     3961 catggccatt gaccagggaa ctacaagttc tcgtgccatc attttcaaca aaaaagggga
     4021 aaaggttagc tcgagtcaaa aagagtttac ccagattttc cctcaggcag gttgggttga
     4081 gcacaatgcc aatgaaattt ggaactctgt tcagtcagtt attgcgggtg ctttcatcga
     4141 aagtggtgtc aagccaaatc aaatcgaggc aatcgggatt accaaccaac gtgaaacaac
     4201 ggttgtctgg gataagaaaa caggacttcc tatctacaat gctatcgttt ggcagtcacg
     4261 ccagacagca cctttggctg agcaactaaa aagccaaggt tatgtggaaa aattccatga
     4321 aaagactggt ttgattattg atgcttactt ctctgctacc aaggttcgtt ggattttgga
     4381 tcatgtagaa ggtgctcaag agcgagcaga aaaaggggaa ttgctctttg gtactatcga
     4441 tacttggttg gtttggaaat tgactgacgg tgcggctcac gtgactgact actcaaatgc
     4501 agctcgtacc atgctttata acattaaaga actcaaatgg gatgatgaga ttttggaaat
     4561 ccttaacatt ccgaaggcta tacttccaga agttcgttct aactccgaaa tctacggcaa
     4621 gacagctcca ttccatttct acggtggaga ggtgccaatc tcaggtatgg ctggggacca
     4681 acaagcagcc ctctttggac agttggcttt tgagccaggt atggttaaga atacttatgg
     4741 aacaggctct ttcatcatca tgaatactgg ggaagagatg cagttgtctg aaaacaacct
     4801 cttgacaacc attggttacg gaatcaacgg taaggtttat tatgccttgg aaggttctat
     4861 cttcatcgca ggaagtgcta ttcagtggct tcgtgacggt cttcgcatgg ttgaaaattc
     4921 accagaatct gaaaaatacg ctcgtgattc tcacaacaac gatgaagttt atgtcgttcc
     4981 agcctttaca ggtctaggcg ctccatactg gaaccaaaat gctcgtggtt ccgtctttgg
     5041 tttgactcgt ggaacaagca aagaagactt tatcaaggcg actttgcaat ctattgctta
     5101 tcaagtgcgt gatatcatcg acaccatgca agtggatact cagaccgcca ttcaagtact
     5161 gaaggtggat ggtggtgcag ccatgaacaa cttcctcatg cagttccagg cggatatttt
     5221 aggcattgac attgcacgtg ctaaaaacct ggaaacaaca gctctaggag cggccttcct
     5281 agcaggtttg tcagtagggt actggaaaga cttggacgag ttgaaactct tgaacgagac
     5341 aggagaactc tttgagccat ctatgaacga atctcgcaag gaacaactct acaagggctg
     5401 gaagaaggct gtgaaagcaa ctcaagtctt tgcggaagta gacgactaat actggcagaa
     5461 taaagcgatt tatttagaaa gtgtgtaaat atggaatttt caaagaaaac acgtgaattg
     5521 tcaattaaaa aaatgcagga acgcaccctg gacctcttga ttatcggtgg aggaatcaca
     5581 ggagctggtg tagccttgca ggcggcagct agcggtcttg agactggttt gattgaaatg
     5641 caagactttg cagaaggaac atctagtcgt tcaacaaaat tggttcacgg aggacttcgt
     5701 taccttaaac aattcgacgt agaagtggtc tcagatacgg tttctgaacg tgcagtggtt
     5761 caacaaatcg ctccacacat tccaaaacca gacccaatgc tcttaccagt ttacgatgaa
     5821 gatggagcaa cctttagcct cttccgtctt aaagtagcca tggacttgta cgacctcttg
     5881 gcaggtgtta gcaacacacc aactgcgaac aaggttttga gcaaggatca agtcttggaa
     5941 cgccagccaa acttgaagaa ggaaggcttg gtaggaggtg gagtgtatct tgacttccgt
     6001 aacaacgatg cgcgtctcgt gattgaaaac atcaaacgtg ccaaccaaga cggtgccctc
     6061 attgccaacc acgtgaaggc agaaggcttc ctctttgacg aaagtggcaa gattacaggt
     6121 gttgtagctc gtgatctctt gacagaccaa gtatttgaaa tcaaggcccg tctggttatt
     6181 aatacaacag gtccttggag tgataaagta cgtaatttgt ctaataaggg aacgcaattc
     6241 tcacaaatgc gcccaactaa gggagttcac ttggtagtgg attcaagcaa aatcaaggtt
     6301 tcacagccag tttactttga cacaggtttg ggtgacggtc gtatggtctt tgttctccca
     6361 cgtgaaaaca agacttactt tggtacaact gatacagact acacaggtga tttggagcat
     6421 ccaaaagtaa ctcaagaaga tgtagattat ctacttggca ttgtcaacaa ccgctttcca
     6481 gaatccaaca tcaccattga tgatatcgaa agcagctggg caggtcttcg tccattgatt
     6541 gcagggaaca gtgcctctga ctataatggt ggaaataacg gtaccatcag tgatgaaagc
     6601 tttgacaact tgattgcgac tgttgaatct tatctctcca aagaaaaaac acgtgaagat
     6661 gttgagtctg ctgtcagcaa gcttgaaagt agcacatctg agaaacattt ggatccatct
     6721 gcagtttctc gtgggtctag cttggaccgt gatgacaatg gtcttttgac tcttgctggc
     6781 ggtaaaatca cagactaccg taagatggct gaaggagcta tggagcgcgt ggttgacatc
     6841 ctcaaagcag aatttgaccg tagctttaaa ttgatcaatt ctaaaactta ccctgtttca
     6901 ggtggagaat tgaacccagc aaatgtggat tcagaaatcg aagcctttgc gcaacttgga
     6961 gtatcacgtg gtttggatag caaggaagct cactatctgg caaatcttta cggttcaaat
     7021 gcaccgaaag tctttgcact tgctcacagc ttggaacaag cgccaggact cagcttggca
     7081 gatactttgt cccttcacta tgcaatgcgc aacgagttgg ctcttagccc agttgacttc
     7141 cttcttcgtc gtaccaacca tatgctcttt atgcgtgata gcttggatag catcgttgag
     7201 ccaattttgg atgaaatggg acgattctat gactggacag aagaagaaaa agcaacttac
     7261 cgtgctgatg tcgaagcagc tctcgctaac aacgatttag cagaattaaa aaattaagaa
     7321 aaaataaaag aggtggaggg cagcattcct tgtcgcccgt cccttctttt taatggagac
     7381 agaaagatga tgaatgaatt atttggagaa tttctaggga ctttaatcct gattcttcta
     7441 ggaaatggtg ttgttgcagg tgtggttctt cctaaaacca agagcaatag ctcaggttgg
     7501 attgtgatta ctatgggttg ggggattgca gttgcggttg cagtctttgt atctggcaag
     7561 ctcagtccag ctcatttaaa cccagctgtg accatcggtg tggccttaaa aggtggtttg
     7621 ccttgggctt ccgttttgcc ttatatctta gcccagttcg caggggccat gctgggtcag
     7681 attttggttt ggttgcaatt caaacctcac tatgaggcag aagaaaatgc aggcaatatc
     7741 ctggcaacct tcagtactgg accagccatc aaggatactg tatcaaactt gattagcgaa
     7801 atccttggaa cctttgtttt ggtgttgaca atctttgctt tgggtcttta cgattttcag
     7861 gcaggtatcg gaacctttgc agtgggaact ttgattgtcg gtatcggtct atcactaggt
     7921 gggacaacag gttatgcctt gaacccagct cgtgaccttg gacctcgtat catgcacagc
     7981 atcttgccaa ttccaaacaa gggagacgga gactggtctt acgcttggat tcctgttgta
     8041 ggccctgtta tcggagcagc cttggcagtg cttgtattct cacttttcta gtttatactc
     8101 ttcgaaaatc aaattcaaac cacgtcagcg tcgccttacc gtactcaagt acagcttacg
     8161 gctagcttcc tagtttgctc tttgattttc attgagtatt agaaaacaat tatgttgata
     8221 gagcttgggc aagagcccaa tttcagcaaa aaatgaagta aatcttctca taataaaacg
     8281 catcatatca agcacgaaaa ttccacgagg tcaactacag tcagaaagct gaacaacaag
     8341 ccaaaacgcc caaaaaaggc ggcaaaaagc aagcacctgc aagcaacgtg ccgaaatggt
     8401 caaatcctga ttatgtcaac gaattagacc caaaaatcgt tgatatgcta gtagaatttc
     8461 acaagtcaca aggcactttg gaaactcccg aggcgcaagc agaaatcgcc caaaaacgtg
     8521 aagaaatcga gcaaaggaga gctgagcttg aggataaaaa acaagagctt ttgaaccgct
     8581 tgaacaaata gagtttcgca agtattatgc ttacaaatta cttgagcaat taactaaaat
     8641 ataaaccctg cctttatatc taggcagggt ttatatttta gaaattcacg taggttgtta
     8701 cggtttttac atacccagta tagtttgagt ttctatagta ttcagtgata aacttccatt
     8761 ttttttgagc aacatggata taagtacttg ttatgtagta tggatatggg ctttgtgaat
     8821 ccaagtaaga ctgataagct tgtataccaa aatatgctcc accaattatt gcaccccatg
     8881 gaccccccaa taaagtacct atcctaccaa tcatataact gattccagca ccagtcatga
     8941 agttagcgaa tgtgttagct tgtttattcc catgtattgt gttgacgtaa ttccaaacat
     9001 taggatcgta tgatctaaaa gatatattta ggtcgatttc attcttttga taagccatat
     9061 aaaatgcccc attgatatag acgccgtcag cacgtcgttc aatagtgtct acacttccat
     9121 ctggattgac aacctcaaga acttcatcgc ttaaaatatt tacttgcgta tctccgaacc
     9181 gcactgatga gccattctca aactgagcct caccagatac aactttagag tttgccgata
     9241 agctatcatc agcaaaaaca aacaagcgac ggggaaatgc tagacataca gaaaacagac
     9301 ataactagca aacacatgca tttaaacatc ttagacataa cggaaactcc tttgtatttt
     9361 tgattttttt caacttttat tatacaataa aaccaaataa aaagaaagcg gtaacaatat
     9421 gcttaatgcg aaaatttttt atatattttt atgtttgatc gttatcgaaa ctacaggctt
     9481 gttgttgttg aaaagaggtc tcgaaatggg ttatttagac acagaagcta ttatcctcgc
     9541 agttttttca tttgcttttt acaacctatg ttcattcgct tgggtctgct ctacaataaa
     9601 aaacaataaa aaataaatag acgtattttc aaaaaaaaaa aaaaaaaatg catatttatc
     9661 ttagcaaaac gacaatttaa atcgtcgttt ttttgtagta cgacgggcat gtcgtatatc
     9721 tgaggtgtaa gtcctcggtg ggcacctgct accggtgaac ccaatagcga ttcccaagcc
     9781 tgactatcgt gaggtagcag ggagaggaag ggatagcgaa atcgtggctc tacgaacagg
     9841 aacgtgatag taaggcgtat atagcggata aggaggcttc aaactctaaa gtccaaaaag
     9901 gtagtcgtaa cctatatgtg taaatcacga gagtaattga attcggacta aggtttgtgt
     9961 gaaaaagata aatctttcta gagtctaaag actctgcgtc agatttccta ttttcactgt
    10021 aaccttttaa cgtcctcata tcttgtataa acgaggaaag atgtacgact tatcccgtga
    10081 ggtttcatga gcgctgaaag cgtagtaaca acgaatcatg agaagtcagc cgagcccata
    10141 gtagtgagga aacttccgta atggaagtgg agcgaagggg tgaatactca aacagtctgg
    10201 ggagagactg tttgaggtct gtcgctagaa agagaaaacg acagatcgaa gtaatcctac
    10261 ttcacttgtg tctgtaaaat gagtggtctg atagaactgg actttgacac gta
//
LOCUS       DAVBBO010000068         9472 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ST1
            SAMEA2066453-rid20184263.denovo.068, whole genome shotgun sequence.
ACCESSION   DAVBBO010000068 DAVBBO010000000
VERSION     DAVBBO010000068.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2066453
            Sequence Read Archive: ERR351777
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 9472)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9472)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980402.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980402.1
            Genome Coverage       :: 176x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:17:33
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,141
            CDSs (total)                      :: 2,104
            Genes (coding)                    :: 1,953
            CDSs (with protein)               :: 1,953
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 16S)
            partial rRNAs                     :: 1 (23S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 151
            CDSs (without protein)            :: 151
            Pseudo Genes (ambiguous residues) :: 0 of 151
            Pseudo Genes (frameshifted)       :: 73 of 151
            Pseudo Genes (incomplete)         :: 76 of 151
            Pseudo Genes (internal stop)      :: 40 of 151
            Pseudo Genes (multiple problems)  :: 32 of 151
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9472
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2066453-rid20184263.denovo.068"
                     /strain="ST1"
                     /db_xref="taxon:1313"
     gene            150..686
                     /locus_tag="VQU30_001909"
     CDS             150..686
                     /locus_tag="VQU30_001909"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000709035.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="biotin transporter BioY"
                     /protein_id="HET2447959.1"
                     /translation="MKKAHVYAIPAIGAALIAALAQISLPIGPVPFTLQNFAIGLIAT
                     VFRPREAVLSAGLYLLLGAIGLPVFAGGGAGFQALVGPTAGYLWFYLVYSGLTSSLTN
                     SKSGVVKIFLANLLGDALVFVGGILSLHFLAGMAFEKALAVGVLPFIIPDLGKLLAIS
                     FISRPLLQRLKNQAYFTN"
     gene            737..823
                     /locus_tag="VQU30_001910"
                     /pseudo
     CDS             737..823
                     /locus_tag="VQU30_001910"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820552.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopuranose mutase"
     gene            complement(892..1107)
                     /locus_tag="VQU30_001911"
     CDS             complement(892..1107)
                     /locus_tag="VQU30_001911"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000807422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdbC family protein"
                     /protein_id="HET2447960.1"
                     /translation="MAEFTFEIEEHLLTLSENEKGWTKEINRVSFNGAPAKFDIRAWS
                     PDHTKMGKGITLSNEEFQTMVDAFKGN"
     gene            1205..1525
                     /locus_tag="VQU30_001912"
     CDS             1205..1525
                     /locus_tag="VQU30_001912"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001216095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2447961.1"
                     /translation="MRHKFQQVLNKIHDFLNGYDQPDQTETNSLTATIEEAIQKQTAV
                     HLILSETSFTGDIIKYDQQGQQIIVKNFAKNVSRIIRISDIQRLRFVPSTVQTAQKNR
                     FKKE"
     gene            complement(1556..1894)
                     /locus_tag="VQU30_001913"
     CDS             complement(1556..1894)
                     /locus_tag="VQU30_001913"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001196050.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2447962.1"
                     /translation="MQVIKRNGEIAEFNPDKIYQAILKAAQTVYVLTDDLRQNLAQVT
                     KKVVLDLQEAKVERATISMIQSMVEHRLLGAGYITIAEHYISYRLQRDLERSGYGDHI
                     AVHLHFEQIR"
     gene            complement(1906..2625)
                     /gene="trmD"
                     /locus_tag="VQU30_001914"
     CDS             complement(1906..2625)
                     /gene="trmD"
                     /locus_tag="VQU30_001914"
                     /EC_number="2.1.1.228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (guanosine(37)-N1)-methyltransferase TrmD"
                     /protein_id="HET2447963.1"
                     /translation="MKIDILTLFPEMFSPLEHSIVGKAREKGLLDIQYHNFRENAEKA
                     RHVDDEPYGGGQGMLLRAQPIFDSFDAIEKKNPRVILLDPAGKQFDQAYAEDLAQEEE
                     LIFICGHYEGYDERIKTLVTDEISLGDYVLTGGELAAMTMIDATVRLIPEVIGKESSH
                     QDDSFSSGLLEYPQYTRPYDYRGMVVPDVLMSGHHEKIRQWRLYESLKKTYERRPDLL
                     EHYQLTVEEEKMLAEIKENKE"
     gene            complement(2615..3133)
                     /gene="rimM"
                     /locus_tag="VQU30_001915"
     CDS             complement(2615..3133)
                     /gene="rimM"
                     /locus_tag="VQU30_001915"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016465641.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome maturation factor RimM"
                     /protein_id="HET2447964.1"
                     /translation="MNYFNVGKIVNTQGLQGEMRVLSVTDFAEERFKKGAELALFDEK
                     DQFVQTVTIASHRKQKNFDIIKFKDMYHINTIEKYKRYSLKVAEEDLNDLDDGEFYYH
                     EIIGLEVYEGDSLVGTIKEILQPGANDVWVVKRKGKRDLLLPYIPPVVLNVDIPNKRV
                     DVEILEGLDDED"
     gene            complement(3164..3952)
                     /locus_tag="VQU30_001916"
     CDS             complement(3164..3952)
                     /locus_tag="VQU30_001916"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000819180.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HET2447965.1"
                     /translation="MKRFEVSTEIGSLSVTYQKQKKVLVCLNGAGLLPSYENFSLILE
                     KPPPTIGYLTIDFPNTGRSPIHDQAGKNLDNLADAVYEVLEELGISEYILCAHSWSGI
                     LACKLLEKPIKRQTLVAIEPTTKKVMFADFSENPYPEMEEQMRLIDECGPELYFKNLT
                     QATFSPETNKKIWELMQEKGLELENQDPEFQISGEITEEDFEDVSIEAHIPVFVFCQP
                     YREKEYRESEYWTSNTKLILGGNHHYLQWSESEKIAAIIRELSE"
     gene            complement(4529..4768)
                     /locus_tag="VQU30_001917"
     CDS             complement(4529..4768)
                     /locus_tag="VQU30_001917"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005590445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="KH domain-containing protein"
                     /protein_id="HET2447966.1"
                     /translation="MDTIENLIIAIVKPLISQPDALTIKIEDTPEFLEYHLNLDQSDV
                     GRVIGRKGRTISAIRTIVYSVPTEYKKVRIVIDEK"
     gene            complement(4788..5060)
                     /gene="rpsP"
                     /locus_tag="VQU30_001918"
     CDS             complement(4788..5060)
                     /gene="rpsP"
                     /locus_tag="VQU30_001918"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002884675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S16"
                     /protein_id="HET2447967.1"
                     /translation="MAVKIRLTRMGSKKKPFYRINVADSRSPRDGRFIETVGTYNPLV
                     AENQVTLKEDRVLAWLANGAQPSDTVRNILSKEGVLKKFHDSKFSK"
     gene            5230..5439
                     /locus_tag="VQU30_001919"
     CDS             5230..5439
                     /locus_tag="VQU30_001919"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000953868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2447968.1"
                     /translation="MLSVNTILEKFYKEHQVKPFISPERELDTWLLSPKPVPKRNMDL
                     LVDDSLAGDIILLWRIQFGTFTTET"
     gene            5918..6139
                     /locus_tag="VQU30_001920"
     CDS             5918..6139
                     /locus_tag="VQU30_001920"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2447969.1"
                     /translation="MSFYGLFYNGIAITPNTYLSAWFVNFIAALPLNFLIVEPIARFI
                     LSSFQKPFTGEEVEEVEDFQDDDEIPTII"
     gene            6222..7025
                     /locus_tag="VQU30_001921"
     CDS             6222..7025
                     /locus_tag="VQU30_001921"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000731914.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HET2447970.1"
                     /translation="MKKLATLLLLSTVALAGCSSVQRSLRGDDYVDSSLAAEESSKVA
                     AQSAKELNDALTNENANFPQLSKEVAEDEAEVILHTSQGDIRIKLFPKLAPLAVENFL
                     THAKEGYYNGITFHRVIDGFMVQTGDPKGDGTGGQSIWHDKDKTKDKGTGFKNEITPY
                     LYNIRGALAMANTGQPNTNGSQFFINQSSTDTSSKLPTSKYPQKIIEAYKEGGNPSLD
                     GKHPVFGQVIDGMDVVDKIAKAEKDEKDKPTTAITIDSIEVVKDYDFKS"
     gene            complement(7081..8622)
                     /locus_tag="VQU30_001922"
     CDS             complement(7081..8622)
                     /locus_tag="VQU30_001922"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002918612.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HET2447971.1"
                     /translation="MSILEVKNLSHGFGDRAIFEDVSFRLLKGEHIGLVGANGEGKST
                     FMSIVTGKMLPDEGKVEWSKYVTAGYLDQHSVLAERQSVRDVLRTAFDELFKAEARIN
                     DLYMEMAEDGADVDALMEEVGELQDRLESRDFYTLDAKIDEVARALGVMDFGMDTDVT
                     SLSGGQRTKVLLAKLLLEKPDILLLDEPTNYLDAEHIDWLKRYLQNYENAFVLISHDI
                     PFLNDVINIVYHVENQQLTRYSGDYYQFQEVYAMKKSQLEAAYERQQKEIADLKDFVA
                     RNKARVATRNMAMSRQKKLDKMDIIELQSEKPKPSFDFKPARTPGRFIFQAKNLQIGY
                     DLPLTKPLNLTFERNQKVAIIGANGIGKTTLLKSLLGIISPIAGEVERGDYLELGYFE
                     QEVEGGNRQTPLEAVWNAFPALNQAEVRAALARCGLTTKHIESQIQVLSGGEQAKVRF
                     CLLMNRENNVLVLDEPTNHLDVDAKDELKRALKEYRGSILMVCHEPDFYEGWIDQIWD
                     FNNLT"
     gene            complement(8624..9106)
                     /locus_tag="VQU30_001923"
     CDS             complement(8624..9106)
                     /locus_tag="VQU30_001923"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000976721.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanZ family protein"
                     /protein_id="HET2447972.1"
                     /translation="MMKKTYNHILVWGVIFYSICIVYFCFTPQEQSTVGVGTPDIQHL
                     GRLVFLLTPFNSLWKLGEVSDIGQLCWIFLQNILNVFLFFPLIFQLLYLFPNLRKTKK
                     VLLFSFLVSLGIECTQLILDFFFDFNRVFEIDDLWTNTLGGYLAWLLYKRLHKNKIRN
                     "
     gene            complement(9106..>9472)
                     /locus_tag="VQU30_001924"
     CDS             complement(9106..>9472)
                     /locus_tag="VQU30_001924"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001861081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="50S rRNA methyltransferase"
                     /protein_id="HET2447973.1"
                     /translation="KLFAAIEYYIETTNRRVTFEYIMLNEVNDGVEQALELAELLKNI
                     KKSSYVNLIPYNPVSEHDQYSRSPKERVLAFYDTLKKKGGNCVVRQEHGTDIDAACGQ
                     LLFNTMKRDRQKAVAAVNP"
BASE COUNT         2796 a         2028 c         1698 g         2950 t
ORIGIN      
        1 attttcgaat caacaaaaaa attatccaac ttgactagtc acgaaaatcg gctgttacag
       61 tttttgttac cttgttttta aaaaatggtt gacatcgact cctatatgag tataatagtt
      121 atcatacatt agaaaagagg ttaactattt tgaaaaaagc tcacgtttat gctatccctg
      181 ctattggggc tgctctcatt gctgctttgg cacaaatcag tcttccaatt ggacctgttc
      241 ccttcactct gcaaaacttt gcaatcggct tgattgctac tgtctttaga ccgagagagg
      301 ctgtactttc tgctggactc tatcttcttc taggtgctat cggtcttcct gtctttgcag
      361 gaggtggagc tggttttcag gctttagttg gccctactgc aggctatctt tggttttatc
      421 tcgtttactc tggacttact tcctctctaa ccaacagcaa gagtggtgtt gttaagattt
      481 ttcttgcaaa cctcttgggt gatgcccttg tctttgtcgg cgggattctc agcttgcatt
      541 tcctagctgg aatggcattt gaaaaagctc ttgctgtggg ggttcttccc tttatcattc
      601 cagaccttgg caaacttctg gctattagtt ttattagccg tcccctactt caacgcctta
      661 aaaatcaggc ttactttact aactaaaaaa ggatatcgag ttatcatgac tcaatatcct
      721 tttcttttat tttgaaaact tatactcaat gaaaatcaaa gagcaaacta gaaagctagc
      781 cgcaggctgc tcaaaacact gttttgaggt tgtggatgaa actgacgaag tcagtaacca
      841 tacatacggc aaggcaaagc tgacgcggtt tgaagagatt ttcgaagagt attagttgcc
      901 tttaaaggca tccaccatcg tttgaaattc ttcatttgag agagtaatcc ctttgcccat
      961 tttagtatgg tctggactcc aagcacgaat atcaaacttt gcaggggcac cattaaagct
     1021 cacacggtta atttccttgg tccaaccttt ttcgttttca gaaagagtca acaagtgctc
     1081 ttcgatttca aatgtaaatt ctgccatttt cttctccttt tttagtttca ttagtttatt
     1141 cgtaaaatct tgtagatttt aggaaaattt tatataatat tgatataaaa gaagggaggc
     1201 caatatgaga cataaattcc agcaagttct aaataaaata catgattttt taaatggata
     1261 tgaccaacct gaccagactg aaaccaactc ccttacagcc actattgaag aggctatcca
     1321 gaaacaaacc gctgttcacc ttatcttgtc tgagacaagt tttacaggtg atatcatcaa
     1381 atatgatcag caaggccagc aaattatcgt gaaaaatttt gccaaaaatg tgagccggat
     1441 tatccgtata agcgatattc aacgcctgcg atttgtcccc tcaactgtcc aaacagccca
     1501 aaaaaataga tttaagaaag agtgagatgt agttgcttca tcccactctt ttttcttagc
     1561 gaatttgttc aaaatgtaaa tgaactgcaa tatgatctcc ataaccactt ctttccaagt
     1621 cacgttgtaa acgataggaa atgtagtgtt ctgcaatggt aatgtaacct gcgcccaata
     1681 aacgatgttc aaccatagat tgaatcatac tgatagtcgc acgttccacc ttggcttctt
     1741 gtaaatccaa aactaccttc ttagtgactt gagcaagatt ttgacgcaaa tcatctgtca
     1801 aaacataaac agtttgggct gccttcaaga tggcttggta aatcttatct ggattaaatt
     1861 cagcaatttc gccattacgt ttgattactt gcataggttt ctcctttatt ctttgttttc
     1921 tttgatttct gccagcattt tttcttcttc tactgtcagt tgataatgtt caagtaaatc
     1981 cggtctgcgc tcgtaggttt tctttaaact ctcgtacaat cgccactgac gaatcttttc
     2041 atggtggcca ctcatcaata catctggcac gaccatgcct cgataatcat agggacgtgt
     2101 gtactgagga tattctaaaa gacctgaaga aaaactatca tcttggtggc tagactcctt
     2161 gccaatcact tctggaatca ggcgaactgt agcatcaatc atggtcatag ctgccaattc
     2221 tccaccagtg aggacatagt cgcctaggga aatctcatct gttaccaagg tcttaatgcg
     2281 ctcatcataa ccctcatagt gcccacagat aaagattagc tcttcctctt gagccaaatc
     2341 ttcagcataa gcctgatcaa actgctttcc agcaggatcg aggagaataa cgcgcggatt
     2401 tttcttttca atagcatcaa aggaatcgaa aataggttgt gctctgagca acatgccctg
     2461 accgcctccg tagggctcat catctacatg acgggccttt tcagcatttt ctcgaaaatt
     2521 atgatactgg atatccaaga gccctttttc tcgagccttt ccaacgattg agtgctccag
     2581 tggagaaaac atctctggaa agagggttaa aatatcaatc ttcatcgtct aacccttcta
     2641 agatttccac atcgacccgt ttatttggaa tatcaacatt gagaaccact ggtgggatat
     2701 aaggtaaaag caaatcacgt ttgccttttc gtttgaccac ccagacatca ttagcacctg
     2761 gttgcaggat ttccttgatg gttccaacca agctatcacc ctcatagact tccaaaccga
     2821 taatctcgtg atagtaaaat tcaccatcgt ctaggtcatt caaatcttcc tcagcgacct
     2881 tgagactata tctcttgtac ttttcgatag tattgatatg gtacatatct ttgaatttaa
     2941 taatgtcaaa gttcttctgt ttacggtggc tagcgatggt cactgtttgg acaaactgat
     3001 ctttttcatc aaacaaagcc agctcagctc cttttttaaa ccgttcttct gcaaaatccg
     3061 tcacagacaa gactcgcatc tcaccctgta atccctgcgt attaacgatt ttcccaacat
     3121 taaagtagtt catcttgtct cctgtaatct ccttttttcc atcttattct gacaattctc
     3181 gaataatagc cgcaattttt tccgattctg accattgtaa ataatggtga ttccctccta
     3241 aaatgagttt agtattggaa gtccaatatt ctgattctct gtactctttt tctctataag
     3301 gctgacaaaa aacaaataca ggaatatgag cttctataga tacatcctca aaatcttcct
     3361 cagtaatctc tccagatatc tgaaattctg gatcttgatt ttccaactct aagccttttt
     3421 cttgcattaa ttcccagatt tttttattcg tttcaggact aaatgttgct tgagttaagt
     3481 tcttaaaata aagttcagga ccacactcgt caatcagcct catctgctct tccatttctg
     3541 gataaggatt ttctgaaaaa tcagcaaaca tgactttttt agttgtcggt tcaattgcta
     3601 ctaaagtctg acgcttaatt ggtttctcga gtaatttgca agctaaaatt ccactccaac
     3661 tatgtgcaca aagtatatat tcagaaattc ctaattcttc aagtacttca taaaccgcat
     3721 ctgcaagatt atctagattt tttccagctt ggtcatgaat cggactccta cctgtgttcg
     3781 gaaaatcaat tgtcaaataa ccaattgtag gaggaggttt ttcaagtata agtgaaaaat
     3841 tttcataact tggtagcaaa cctgctccgt ttagacaaac tagcactttc ttttgctttt
     3901 gataagtaac agagaggcta ccaatttctg tagatacttc aaacctcttc ataaagaaat
     3961 ccactcattc tatataatga attattaaaa atccttatct tttattttat cacgttccaa
     4021 ggattttctc aagttggagg aaggggacaa catctctact ttcccttcaa aaatccttcc
     4081 aaatcatgtt tatgttggta attaacggct gcggttttgt ctttctcaaa gacagtcttg
     4141 gtaaggtcaa tatgattaat agctacgatt gcgacggtgt agtaaatgat atcagccagt
     4201 tctctggcaa gttcctcgtt cgaatcctat cccttctttt cgaccagagc gcctattcaa
     4261 aacctcggct acttctccga cttcctccac taacttcata aagagacctt catcagtccg
     4321 agactgctgt taatgttcga ttaagtagtc ttggaattgc ctaaacgttc aatcttttat
     4381 agtatattga aactagaata gtacaccttt acttctaaaa cattgttaga aatcgatttg
     4441 actgtcctga tcgatttgtc ctgttcttgt ttcattttac tatatcttct attccacaca
     4501 aaaaagcgag acatccgtcc cgcccttctt atttttcgtc aataacgatt cttacttttt
     4561 tgtattcagt tgggacagag tagacaatcg ttcttatcgc agaaatagtg cgacccttac
     4621 gaccgattac acgacccaca tcgctttgat caagattcaa atgatattcc aaaaattctg
     4681 gtgtatcctc aatcttgata gttaaggcat ctggttgtga aattaagggt ttcacaatcg
     4741 caataatgag attttcaatc gtatccatct gtcaacctac tttaaactta ttttgaaaat
     4801 ttagaatcgt ggaatttttt caatacgcct tcttttgaaa ggatgttacg tactgtgtct
     4861 gaaggttgag ctccattagc caaccatgca agaacgcggt cttctttcaa agttacttgg
     4921 ttttcagcaa caagtgggtt gtaagttcca actgtttcga tgaaacgtcc gtcacgtggt
     4981 gaacgtgaat ctgctacgtt gatacggtag aaaggttttt tcttagaacc catacgagtc
     5041 aaacggattt taactgccat ttttaaagtc tcatttcttt aattttttat ttcggtgaaa
     5101 tagctgagct atttagcaca tgttctatta tagcagattt ctggcatgtg tcaagaaaaa
     5161 aacttgacag actataaatt tcttaaagta tttagaaatt tgttagaata ggaaataaat
     5221 gtttgaaaga tgctatccgt gaatactatt ttagaaaaat tttataaaga acaccaagtc
     5281 aaacccttca tatcgcctga acgagagttg gatacttggc ttctaagtcc caagcccgtt
     5341 cccaagcgaa atatggactt attagtagat gattcactag caggagatat cattttacta
     5401 tggagaatcc agtttggtac ttttaccact gaaacatgat tttaaaaact cccattcgaa
     5461 tatgattcaa aattcgctta gaatcaatgt tttcccgctt tttcaaaaaa taaattttca
     5521 tctaatttaa ataactttca attaagtgtg aattttgctt aaaatcatta aaaagcaccc
     5581 catggtgtga accatgaagt gttgtaaatg ctgtgttgta gctagttctt agcgtttaga
     5641 gaactggcta gctttacgag ctttcttaag atctggtttc caaaatactt tgagtacact
     5701 tatggtattg atgcccctaa acatctaaaa actctggtag aaaaagggta tgctcttgtc
     5761 gaaacttctt ttgactcact tgaccatcta aataatacca tgaaaaagaa tatcctgaag
     5821 aagaagggag ttactggact ttctaaaatg aaatcttgcg acctggatca agcccttcat
     5881 gagcattttt cagaagaaga attagctggt cactttcatg tccttctatg gactttttta
     5941 caatggcatt gctatcacac ccaataccta tctaagcgcc tggttcgtaa actttattgc
     6001 agctcttcct ctaaatttcc taattgttga accaattgcc cgttttatac taagttcttt
     6061 tcagaaacca tttactgggg aagaagttga agaagttgaa gattttcaag atgatgatga
     6121 aatcccaact attatctaag ccagttctgt aaactactaa tatttgaaat ccacttcttt
     6181 ttagggtaca atggtataaa tgaatttttg agaggatcag aatgaaaaaa ctagcaaccc
     6241 ttcttttact gtctactgta gccctagctg ggtgtagcag cgtccaacgc agtctgcgtg
     6301 gtgatgatta tgttgattcc agtcttgctg ctgaagaaag ttccaaagta gctgcccaat
     6361 ctgccaagga gttaaacgat gctttaacaa acgaaaacgc caatttccca caactatcta
     6421 aggaagttgc tgaagatgaa gccgaagtga ttctccacac aagccaaggt gatattcgca
     6481 ttaaactctt ccctaaactc gctcctctag cggttgaaaa tttcctcact cacgccaaag
     6541 aaggctacta taacggtatt accttccacc gtgtcatcga tggctttatg gtccaaactg
     6601 gagatccaaa aggggacggt acaggtggtc agtccatctg gcatgacaag gataagacta
     6661 aagacaaagg aactggtttc aagaacgaga ttactcctta tttgtataac atccgtggtg
     6721 ctcttgctat ggctaatact ggtcaaccaa acaccaatgg cagccagttc ttcatcaacc
     6781 aaagctctac agatacctct tctaaactcc ctacaagcaa gtatccacag aaaattatcg
     6841 aagcctacaa agaaggtgga aaccctagtc tagatggcaa acacccagtc tttggtcaag
     6901 tgattgacgg tatggatgtt gtggataaga ttgctaaggc cgaaaaagat gaaaaagaca
     6961 agccaactac tgctatcaca atcgacagca tcgaagtggt gaaagactac gattttaaat
     7021 cttaaaaacc aaaaaaatac agtatccaca ttcggtactg tatttctttt actctcattc
     7081 ttaagttaaa ttattaaaat cccatatttg gtctatccag ccttcataaa agtctggctc
     7141 gtggcagacc ataaggatag atcccctata ttctttgaga gcgcgtttga gctcatcctt
     7201 tgcatccaca tccaaatggt tggtcggctc gtccagcact aaaacgttgt tttcacgatt
     7261 catcaagaga cagaaacgaa ccttggcttg ctctccccct gataatactt gaatctggct
     7321 ttcaatatgt ttggttgtca aaccacaacg ggcaagggct gcacggactt ctgcttgatt
     7381 aagggcagga aaggcattcc agacagcttc aagaggagtt tggcgattac cgccttctac
     7441 ttcctgctca aaataaccaa gttctaaata atctccacgc tccacttccc cagcgattgg
     7501 cgagataatg cccaagagac tcttcaagag agttgttttt ccaataccat tagcaccaat
     7561 aatcgcaacc ttttgattgc gttcgaaggt aagatttaaa ggcttagtaa gaggaaggtc
     7621 gtaaccaatt tgcaagttct tggcttggaa gataaagcgc cctggtgtac gagctggttt
     7681 gaaatcaaag gatggttttg gtttctcact ttggagttcg ataatatcca tcttatccaa
     7741 tttcttttga cgagacatag ccatattacg agttgcaaca cgggctttat tacgagccac
     7801 aaagtccttg aggtctgcaa tctctttctg ctggcgttcg taggctgcct ctagctgaga
     7861 tttcttcata gcataaactt cttggaactg gtagtagtca ccagagtaac gcgtcagctg
     7921 ttgattttcc acatgataga caatattgat aacgtcattg aggaatggaa tatcgtgcga
     7981 aatgagaaca aaggcattct catagttttg gagatagcgc ttgagccaat caatatgctc
     8041 agcatccaag tagttggtcg gctcgtccaa cagcaagata tcaggctttt caaggagaag
     8101 ttttgccaaa agcaccttgg ttctttgccc acctgacaaa gaagttacat ccgtatccat
     8161 gccaaagtcc ataacaccaa gagcacgcgc tacttcgtca atcttagcat ccaaggtata
     8221 gaaatcacga ctctccagac ggtcttgaag ttctcctact tcttccatga gagcatcaac
     8281 atccgcaccg tcttcagcca tttccatata gaggtcattg atacgagctt cagctttgaa
     8341 aagctcatca aaagccgtac ggagaacatc acgcaccgac tgtctttcag caaggacaga
     8401 gtgctgatcc aagtaaccag ccgtcacata tttggaccac tcaacctttc cttcatctgg
     8461 cagcatttta ccagtcacga tactcataaa ggttgatttt ccttcaccat tggcaccgac
     8521 caggccgata tgttctccct tgaggagacg gaaggacaca tcttcaaaaa ttgcacggtc
     8581 accaaaaccg tgactcagat ttttaacttc taaaatactc attttaattc cttatcttgt
     8641 ttttatgtaa tcgtttataa aggagccaag ccagatagcc acccaaagtg ttggtccaca
     8701 aatcatcaat ctcaaagacg cgattgaaat caaagaaaaa gtccaagatt aattgcgtac
     8761 actcgattcc aagactcaca agaaaactaa aaagaaggac cttttttgtt ttccgcaaat
     8821 ttggaaatag ataaaggagt tggaaaatca gaggaaaaaa caagaagaca ttgaggatat
     8881 tttgtaaaaa aatccaacat aattgtccaa tgtcactcac ttcgcccagt ttccagagag
     8941 aattgaaagg agtcaaaaga aaaaccaggc gtccaagatg ctgaatatct ggagttccca
     9001 ctcccacggt agattgttct tgaggagtaa agcaaaaata gacaatgcaa atgctataga
     9061 aaatgactcc ccagaccaaa atatgattat aagtcttctt catcattaag gatttaccgc
     9121 tgcgactgcc ttctggcggt cacgtttcat tgtgttaaag agcaattgtc cacaagctgc
     9181 gtcaatatct gtaccatgct cttgacgaac cacacagttg cccccttttt tcttaagcgt
     9241 atcatagaaa gccaacacgc gctctttggg actacggcta tattggtcat gctcactaac
     9301 tgggttataa ggaatcaagt ttacataaga cgatttcttg atgttcttga gcaattcagc
     9361 caattccaag gcttgttcca caccgtcgtt gacttcatta agcatgatat attcaaaggt
     9421 tacacgacgg tttgttgtct caatgtagta ttcaatagca gcaaagagtt tt
//
LOCUS       DAVBBO010000069         9171 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ST1
            SAMEA2066453-rid20184263.denovo.069, whole genome shotgun sequence.
ACCESSION   DAVBBO010000069 DAVBBO010000000
VERSION     DAVBBO010000069.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2066453
            Sequence Read Archive: ERR351777
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 9171)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9171)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980402.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980402.1
            Genome Coverage       :: 176x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:17:33
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,141
            CDSs (total)                      :: 2,104
            Genes (coding)                    :: 1,953
            CDSs (with protein)               :: 1,953
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 16S)
            partial rRNAs                     :: 1 (23S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 151
            CDSs (without protein)            :: 151
            Pseudo Genes (ambiguous residues) :: 0 of 151
            Pseudo Genes (frameshifted)       :: 73 of 151
            Pseudo Genes (incomplete)         :: 76 of 151
            Pseudo Genes (internal stop)      :: 40 of 151
            Pseudo Genes (multiple problems)  :: 32 of 151
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9171
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2066453-rid20184263.denovo.069"
                     /strain="ST1"
                     /db_xref="taxon:1313"
     gene            complement(<1..543)
                     /locus_tag="VQU30_001925"
     CDS             complement(<1..543)
                     /locus_tag="VQU30_001925"
                     /EC_number="2.7.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004261526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I pantothenate kinase"
                     /protein_id="HET2447974.1"
                     /translation="MTNEFLHFEKISRQTWQSLHRKTTPPLTEEELESIKSFNDQISL
                     QDVTDIYLPLAHLIQIYKRTKEDLAFSKGIFLQRESKSQPFIIGVSGSVAVGKSTTSR
                     LLQILLSRTFTDATVELVTTDGFLYPNQTLIEQGILNRKGFPESYDMEALLNFLDRIK
                     NGQDVDIPVYSHEVYDIVPEK"
     gene            733..1137
                     /locus_tag="VQU30_001926"
     CDS             733..1137
                     /locus_tag="VQU30_001926"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000698118.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2447975.1"
                     /translation="MKILKRYILELCFILSFALPFIKGTNADNGRCFVETYYGFTFLM
                     EHAIVTAVFIYSFLIAFLLKKRWAKWIAAGSYCFLVLWIATEGYFFRMSLEDLIRLWT
                     SLEILTQTYQLGFYLNILLGILLIIKYFKVKQ"
     gene            1353..1934
                     /locus_tag="VQU30_001927"
     CDS             1353..1934
                     /locus_tag="VQU30_001927"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000289981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HET2447976.1"
                     /translation="MYYAENPDAAHDIHELRVDLLGQKMTFLTDAGVFSKKMVDFGSQ
                     LLLKCLDVNQGETVLDVGCGYGPLGLSLVKVYGVQATMVDINTRALDLARRNAEKNNA
                     KATIFQSNIYEQVEGHFDHVISNPPIRAGKQVVHEIIEKSKDFLETGGDLTIVIQKKQ
                     GAPSAKSKMEDVFGNCEILKKDKGYYILRSVKE"
     gene            1931..3208
                     /locus_tag="VQU30_001928"
     CDS             1931..3208
                     /locus_tag="VQU30_001928"
                     /EC_number="2.4.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001202959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyrimidine-nucleoside phosphorylase"
                     /protein_id="HET2447977.1"
                     /translation="MRAVDLIQKKRDGQELTSSEIEWLVEGYVSGTVPDYQMSAFAMA
                     VYFKGMTTREISDLTMNMVKTGQEFDLSAIDGVKVDKHSTGGVGDKVTLILAPLVASF
                     GVPVAKMSGRGLGHTGGTIDKLESIRGYQVERSQEDFIRQVQDIGVSVIGQSDQLVKA
                     DKLLYALRDVTATVDTIPLIASSVMSKKIAAGADAILLDVTVGEGAFMKTVDEARELA
                     QTMVDLGKVVGRKTVAVITDMSQPLGRAIGNRLEILEALEILQGQGRQDITHFICELA
                     QIMLGLANVNKTVEEVHQHLENGQALAKFEEMVQAQGGDLEDLYRPVNVAHVVEIPAQ
                     ETGVISALPAMDFGLYAMRLGAGRAVKSDALDYETGIVFEKKIGDSVQKGEIVAKVYT
                     NEKIPPQLVTDFQKCVKISDEVKKIREIVEIIS"
     gene            3226..3888
                     /gene="deoC"
                     /locus_tag="VQU30_001929"
     CDS             3226..3888
                     /gene="deoC"
                     /locus_tag="VQU30_001929"
                     /EC_number="4.1.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000773666.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="deoxyribose-phosphate aldolase"
                     /protein_id="HET2447978.1"
                     /translation="MKLNKYIDHTLLKQDAKKKQIDSLLSEAREYDFASVCVNPTWVE
                     HAKKGLEGTDVKVCTVVGFPLGATTSAVKAFETKEAIQNGADEIDMVINVGALKSGNL
                     ALVESDIRAVVEASGDKLVKVIIEACLLTDQEKIVVCQLAQKAGADFVKTSTGFSTGG
                     ATIADVTLMRETVGSDMGVKAAGGARSYADALAFVEAGATRIGTSAGVAILKGELADG
                     DY"
     gene            3875..4264
                     /locus_tag="VQU30_001930"
     CDS             3875..4264
                     /locus_tag="VQU30_001930"
                     /EC_number="3.5.4.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytidine deaminase"
                     /protein_id="HET2447979.1"
                     /translation="MATTELIELAIETSKHAYVPYSHFPIGAVLVAKDGSVYTGVNIE
                     NASYPLTNCGERTAIFKAISEGQREFSELIVYGQTEKPISPCGACRQVMAEFFEQDLK
                     VTLVAKDKSTVEMTVGELLPYSFTDLN"
     gene            4354..5406
                     /locus_tag="VQU30_001931"
     CDS             4354..5406
                     /locus_tag="VQU30_001931"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001036143.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BMP family protein"
                     /protein_id="HET2447980.1"
                     /translation="MNKKQWLGLGLVAVAAVGLAACGNRSSRNAASSSDVKTKAAIVT
                     DTGGVDDKSFNQSAWEGLQAWGKEHNLSKDNGFTYFQSTSEADYANNLQQAAGSYNLI
                     FGVGFALNNAVKDAAKEHTDLNYVLIDDVIKDQKNVASVTFADNESGYLAGVAAAKTT
                     KTKQVGFVGGIESEVISRFEAGFKAGVASVDPSIKVQVDYAGSFGDAAKGKTIAAAQY
                     AAGADIVYQVAGGTGAGVFAEAKSLNESRPENEKVWVIGVDRDQEAEGKYTSKDGKES
                     NFVLVSTLKQVGTTVKDISNKAEKGEFPGGQVIVYSLKDKGVDLAVTNLSEEGKKAVE
                     DAKAKILDGSVKVPEK"
     gene            5550..7085
                     /locus_tag="VQU30_001932"
     CDS             5550..7085
                     /locus_tag="VQU30_001932"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000929819.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET2447981.1"
                     /translation="MAHENVIEMRDITKVFGGFVANDKINLHLRKGEIHALLGENGAG
                     KSTLMNMLAGLLEPTSGEIAVNGQVVNLDSPSKAASLGIGMVHQHFMLVEAFTVAENI
                     ILGSELTKNGVLDIAGASKEIKALSERYGLAVDPSAKVADISVGAQQRVEILKTLYRG
                     ADILIFDEPTAVLTPSEIDELMAIMKNLVKEGKSIILITHKLDEIRAVSDRVTVIRRG
                     KSIETVEIAGATNADLAEMMVGRSVSFKTEKQASKPKEVVLSIKDLVVNENRGVPAVK
                     NLSLDVRAGEIVGIAGIDGNGQSELIQAITGLRKVESGSIELKGDSIVGLHPRQITEL
                     SVGHVPEDRHRDGLILEMMISENIALQTYYKEPHSKNGILNYSNITSYAKKLMEEFDV
                     RAASELVPAAALSGGNQQKAIIAREIDRDPDLLIVSQPTRGLDVGAIEYIHKRLIEER
                     DNGKAVLVVSFELDEILNVSDRIAVIHDGKIQGIVSPETTNKQELGVLMAGGNLGKEK
                     SDV"
     gene            7078..8136
                     /locus_tag="VQU30_001933"
     CDS             7078..8136
                     /locus_tag="VQU30_001933"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000038644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HET2447982.1"
                     /translation="MSKKLQQISVPLISVFLGILLGAIVMWIFGYDAIWGYEELFYTA
                     FGSLRGIGEIFRAMGPLVLIGLGFAVASRAGFFNVGLPGQALAGWILSGWFALSHPDM
                     PRPLMILATIVIALIAGGIVGAIPGILRAYLGTSEVIVTIMMNYIVLYVGNAFIHAFP
                     KDFMQSTDSTIRVGANATYQTPWLAELTGNSRMNIGIFFAIIAVAVIWFMLKKTTLGF
                     EIRAVGLNPHASEYAGISAKRTIILSMIISGALAGLGGAVEGLGTFQNVYVQGSSLAI
                     GFNGMAVSLLAANSPIGILFAAFLFGVLQVGAPGMNAAQVPSELVSIVTASIIFFVSV
                     HYLIERFVKPKKQVKGGK"
     gene            8139..9095
                     /locus_tag="VQU30_001934"
     CDS             8139..9095
                     /locus_tag="VQU30_001934"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004261501.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HET2447983.1"
                     /translation="MSIITLLPLLVSSMLIYSAPLIFTSIGGVFSERGGVVNVGLEGI
                     MVMGAFSGVVFNLEFAEQFGAATPWLSLLVAGLVGSVFSIIHAAATVHFRADHVVSGT
                     VLNLMAPALAVFLVKVLYNKGQTDNLSQTFGRFDFPVLANIPVIGDIFFKSTSLLGYL
                     AIAFSFLAWFILFKTQFGLRLRSVGEHPQAADTLGINVYKMRYLGIIISGFLGGIGGA
                     IYAQSISVNFSVTTIVGPGFIALAAMIFGKWNPIGAMLSSLFFGLSQSLAVIGSQLPF
                     LQGVPAVYLQIAPYVLTILVLAAFFGKAVAPKADGINYIKSK"
BASE COUNT         2609 a         1621 c         2159 g         2782 t
ORIGIN      
        1 cttttcgggt acgatgtcgt aaacttcatg agaatagaca ggaatatcta catcttgtcc
       61 atttttgatg cggtccaaga agttgagaag agcttccata tcatagcttt caggaaatcc
      121 tttacgattt aaaatcccct gctcaatcaa ggtttgattg ggatagagaa aaccatcagt
      181 tgtaaccaac tcaaccgtag catctgtaaa cgtacgggac agtaggattt gaagtaggcg
      241 actggttgtg gattttccaa cggcaacact cccagaaacc ccaataataa aaggttgaga
      301 tttactttca cgttggagga aaattccttt tgaaaaggct aaatcttcct tagttcgctt
      361 gtaaatctga atcagatgag ccaaggggag atagatatct gtaacgtctt ggagactgat
      421 ttggtcatta aaactcttga tagattccaa ttcttcttct gtcaaaggag gtgttgtctt
      481 tcgatgtaaa gattgccaag tctggcggct gattttttca aaatgtaaaa attcgttggt
      541 catttgtttt cccctagata ttttgtctat cataccataa aaagctaaaa aaataaagcg
      601 gtttcttgaa tgtggtaagt caatggtata tagtataagt gatcaattta ttgatgaaat
      661 aggagataga ttctactgat ttataagctt ataaaggggg ctttttagtt cacaacttat
      721 aggaggtgta ctatgaaaat cttaaaacgt tacatattgg aactctgttt tattttaagt
      781 tttgctttac cttttataaa aggaaccaat gcagataatg gtagatgctt tgtggaaacc
      841 tattacggtt ttactttttt gatggaacat gctattgtaa cagctgtctt tatctattcg
      901 tttttaattg ctttcttact aaaaaaacga tgggcgaaat ggattgctgc tggtagttat
      961 tgctttttag tcctatggat tgcgacagag ggttatttct tccgcatgtc actagaagat
     1021 ttgatacgac tttggacaag tttggaaatc ctgacacaaa cgtatcagtt gggcttttat
     1081 ctaaacattt tgttaggaat tttgttgata ataaagtatt ttaaggttaa gcaatagaaa
     1141 taataatctg cctgattata gatgataaac tttttgtttt tatctggact gtgatattta
     1201 tagttctaaa tggtttatta tttataagtg ttgaaagaga ttgaagaaaa tggcttcgtg
     1261 acttgctttc ttcggtcttt ttcgttttat tatcaatttg taaacgattt acaatttgag
     1321 tcaaattatg gtaaaatagt gtcatgagta aaatgtatta tgcagaaaat cctgacgctg
     1381 ctcacgacat tcatgagttg agagtggact tgttgggaca aaaaatgact tttttgacag
     1441 atgcgggtgt ttttagcaag aaaatggttg actttggaag tcaactcttg ctcaagtgtc
     1501 tggatgtcaa ccaaggagag acagtcctag atgtaggctg tggttatggt ccattaggtt
     1561 tgtccttggt caaggtttac ggagttcagg cgaccatggt tgatattaac actcgtgcct
     1621 tggatttagc tcggagaaat gctgaaaaaa ataatgcaaa agcgacgatt ttccagtcca
     1681 acatctatga acaagttgaa ggacattttg atcatgtcat ttccaatcct cctatccgtg
     1741 cgggcaagca agtcgttcat gaaatcattg agaaaagtaa agatttcttg gaaactggtg
     1801 gggatttgac aatcgtcatc cagaaaaaac aaggggctcc aagtgctaag tccaagatgg
     1861 aggatgtgtt tggtaattgt gaaatcctta aaaaagacaa aggatactat atccttagaa
     1921 gtgtgaaaga atgagagcag ttgatttaat acaaaaaaaa cgagacggtc aagaactgac
     1981 ttcaagtgaa attgaatggc tggtagaagg ctatgtgtca ggaactgttc ctgattatca
     2041 gatgtctgcc tttgctatgg ctgtttattt taaaggaatg acgactcgtg aaatttctga
     2101 tttaacgatg aatatggtta agactgggca agagtttgac ctgtcagcca ttgatggtgt
     2161 gaaagttgac aagcattcta ctggtggtgt cggcgataag gtaaccttga ttttagctcc
     2221 tcttgttgct agcttcggtg tgcctgtagc aaaaatgagt ggtcgtggtc ttggccatac
     2281 aggcggaaca attgataaat tggagtccat taggggctat caagtagaac gtagtcaaga
     2341 ggattttatt cgtcaggttc aggatattgg agtatctgtc attgggcaat cagaccagct
     2401 ggtcaaagca gataagcttc tctatgccct tcgtgatgtg accgcaactg tcgacacgat
     2461 tcctttgatt gcgagttcgg tgatgagcaa gaaaattgcg gcaggggcgg atgctatttt
     2521 gctagacgtg actgtcggtg agggtgcctt catgaagacg gttgatgagg cgcgtgagtt
     2581 ggctcaaact atggtagatc ttggtaaggt tgttggacgg aagacagtag cagtgattac
     2641 ggatatgagc cagcctttgg gacgagcgat tggaaatcgt ctggaaatac ttgaagcatt
     2701 ggagattttg caaggtcaag gacgtcagga tattacccac tttatttgtg aattggctca
     2761 aattatgctt ggtttggcaa atgttaacaa gactgttgaa gaagttcacc aacatcttga
     2821 gaatggtcaa gcactggcta agtttgagga aatggtgcaa gcccaaggtg gagacttgga
     2881 agacctctat cgtcctgtaa atgtagctca tgtggtggaa atccctgctc aggaaacggg
     2941 tgtcatttca gctcttccag ctatggactt tggtctttat gccatgaggc tgggggctgg
     3001 tcgtgcagtt aagtctgatg ccttggacta tgaaacagga attgtttttg aaaagaagat
     3061 tggagactcc gttcaaaagg gtgaaattgt tgcaaaagta tacacaaatg aaaaaattcc
     3121 acctcaacta gttacagatt tccaaaaatg tgttaaaata agtgatgaag tgaaaaaaat
     3181 ccgtgaaatt gtagaaatca tctcctaaat ggagggaaaa ccgaaatgaa attaaataaa
     3241 tatatagatc atacgctttt aaaacaagat gcaaagaaaa aacaaattga tagtttgttg
     3301 tctgaggcta gagagtatga ctttgccagt gtttgcgtta atccgacctg ggttgaacat
     3361 gctaaaaaag gacttgaagg cacagatgtt aaggtttgca cggtagtagg tttccctttg
     3421 ggagcaacaa cttcagccgt gaaagcattt gagacaaaag aagctatcca aaatggtgca
     3481 gatgagattg atatggtgat caatgttgga gctctcaaat caggtaattt agccttggtt
     3541 gagtcagata ttcgcgcagt agtggaagca agtggtgata agttagtgaa agtcattatt
     3601 gaagcttgcc ttctgacaga ccaagaaaaa attgttgttt gccaattggc ccaaaaagct
     3661 ggggctgact ttgttaaaac atctactggt ttttcaactg gtggtgctac gatagcagat
     3721 gttacattaa tgcgtgaaac agttggatct gatatgggag tcaaggctgc tggtggagct
     3781 cgttcttatg cagatgctct tgcctttgtc gaagcaggtg cgacccgtat cggaacgtca
     3841 gctggggtag ctattttaaa aggagaattg gcagatggcg actactgagt tgattgaact
     3901 ggcaattgaa accagcaaac atgcctatgt cccctattct cactttccta tcggagcagt
     3961 tttagtagcc aaagacggaa gtgtttacac gggagtgaat atcgaaaatg ctagctatcc
     4021 tttgaccaat tgcggtgaga gaacagctat ttttaaggct atatctgaag gccaaagaga
     4081 attttcagaa ttgattgtct atggtcaaac tgaaaaaccg atctcgccat gtggtgcttg
     4141 tcgccaagtg atggctgaat tttttgaaca agatctaaaa gtgaccttag tcgcaaaaga
     4201 taaatcgacg gtcgagatga cggtcgggga attacttcca tactctttta cagacttaaa
     4261 ctagtctgag tcgctctctg agtggcacgg tccttgtggc caaccaatcc atacttgcaa
     4321 catcgttgca catcttattt aggaggttca gtaatgaaca agaaacaatg gctaggtctt
     4381 ggcctagttg cagtggcagc agttggactt gctgcatgtg gtaaccgctc ttctcgtaac
     4441 gcagcttcat cttctgatgt gaagacaaaa gcagcaatcg tcactgatac tggtggtgtt
     4501 gatgacaaat cattcaacca atcagcttgg gaaggtttgc aggcttgggg taaagaacac
     4561 aatctttcaa aagataacgg tttcacttac ttccaatcaa caagtgaagc tgactacgct
     4621 aacaacttgc aacaagcggc tggaagttac aacctaatct tcggtgttgg ttttgccctt
     4681 aataatgcag ttaaagatgc agcaaaagaa cacactgact tgaactatgt cttgattgat
     4741 gatgtgatta aagaccaaaa gaatgttgcg agcgtaactt tcgctgataa tgagtcaggt
     4801 taccttgcag gtgtggctgc agcaaaaaca actaagacaa aacaagttgg ttttgtaggt
     4861 ggtatcgaat ctgaagttat ctctcgtttt gaagcaggat tcaaggctgg tgttgcgtca
     4921 gtagacccat ctatcaaagt ccaagttgac tacgctggtt catttggtga tgcggctaaa
     4981 ggtaaaacaa ttgcagccgc acaatacgca gccggtgcag atattgttta ccaagtagct
     5041 ggtggtacag gtgcaggtgt ctttgcagag gcaaaatctc tcaacgaaag ccgtcctgaa
     5101 aatgaaaaag tttgggttat cggtgttgat cgtgaccaag aagcagaagg taaatacact
     5161 tctaaagatg gcaaagaatc aaactttgtt cttgtatcta ctttgaaaca agttggtaca
     5221 actgtaaaag atatttctaa caaggcagaa aaaggagaat tccctggcgg tcaagtgatc
     5281 gtttactcat tgaaggataa aggggttgac ttggcagtaa caaacctttc agaagaaggt
     5341 aaaaaagctg tcgaagatgc aaaagctaaa atccttgatg gaagcgtaaa agttcctgaa
     5401 aaataatgga tggaagtcat ttcttaggaa gcggccaagg gccgcttttt taagagttga
     5461 gacaaagtca ttttgtctca gtaaagcttg ctactagaca aactagcaag ttttattgaa
     5521 ataaaataag actctgaaag gaagagcaca tggcacacga aaatgtcatt gagatgcgtg
     5581 atattaccaa ggtgtttggt ggatttgttg ccaacgacaa aatcaacttg cacctacgaa
     5641 aaggtgaaat tcatgcactt ttaggagaaa atggggctgg taagtccacg ctaatgaaca
     5701 tgttagcagg ccttcttgaa ccaactagtg gtgaaatcgc ggtcaacggt caagttgtca
     5761 atctcgactc cccatctaaa gcagctagct tgggaatcgg gatggttcac cagcacttta
     5821 tgttggttga agccttcaca gtggctgaaa acatcatttt aggtagtgaa ttgactaaaa
     5881 atggtgtgct agatatcgct ggagctagca aagaaatcaa ggctctttct gaacgttatg
     5941 gcttagctgt tgacccttct gccaaggtag cagatatctc agttggagcc caacaacgtg
     6001 tagaaatttt aaaaacactt tatcgggggg ctgatatcct tatctttgac gaaccaacgg
     6061 ctgttttgac tccatcagaa attgatgagt tgatggctat tatgaaaaat cttgtcaaag
     6121 aaggaaaatc aattatcttg attacccaca aattggatga aattcgcgca gtttctgacc
     6181 gtgttacagt tatccgtcgt gggaaatcaa ttgaaaccgt tgaaattgca ggggctacca
     6241 atgctgattt ggcggaaatg atggtaggac gttctgtttc ctttaaaaca gagaagcaag
     6301 cctctaaacc aaaagaagtg gttttgtcta tcaaagattt ggtggtcaat gaaaaccgtg
     6361 gtgttccagc tgttaaaaat ctgtccttgg atgttcgtgc tggagagatt gttggtattg
     6421 cggggattga tggaaatggt cagtctgaac tgattcaagc cattacaggt cttcgtaagg
     6481 ttgaatctgg tagcattgag ctaaaaggag attcaattgt aggcttgcac ccacgtcaga
     6541 ttacagaact aagtgttggg cacgttccag aagaccgtca ccgtgatggc ttgattttgg
     6601 aaatgatgat atctgaaaat attgcccttc aaacctacta taaagaacca catagtaaaa
     6661 atggaatttt gaattattca aatattactt cttatgctaa aaagctgatg gaagagtttg
     6721 atgttcgcgc tgccagtgaa ttagttcctg cagctgcact ctcaggagga aatcaacaaa
     6781 aagcaattat tgctcgtgaa attgatcgag atcctgatct ccttatcgtt agccagccaa
     6841 ctcgtgggtt ggatgtcggt gccattgagt atatccacaa acgcttgatt gaagagcgtg
     6901 ataatggcaa ggctgtcctt gttgtcagct ttgaattgga tgagatttta aacgtctcag
     6961 accgtattgc cgttatccac gatggtaaga ttcaaggtat tgtatcacca gaaacaacca
     7021 ataaacaaga acttggtgtc ttgatggctg gtggaaactt gggaaaggag aagagtgatg
     7081 tctaaaaaat tacaacaaat ttcggttccc ttgatttctg tatttctagg aattttactc
     7141 ggagccattg tcatgtggat cttcggttat gatgctattt ggggctacga agaattgttc
     7201 tatacagcct ttggcagtct gcgtgggatt ggagaaatct tccgtgctat gggtcctctg
     7261 gtcttgattg gtcttggttt tgcggttgcc agtcgagctg gtttctttaa cgtcggactt
     7321 cctggtcagg ctttggcagg ttggattctc agtggttggt ttgcgctgtc gcatccagat
     7381 atgccccgtc ccttgatgat tctagcaacc atcgtgattg ccttgattgc tggtgggatt
     7441 gtcggagcga ttccaggtat tcttagggcc tatctaggga cgtcagaggt tattgtaacc
     7501 atcatgatga actacattgt cttgtatgta gggaatgcct ttatccatgc tttccctaaa
     7561 gacttcatgc aaagtacaga ttcgaccatt cgtgttgggg ctaatgcaac ctatcagaca
     7621 ccttggttgg ctgagttgac tggtaactca cggatgaata ttggtatttt ctttgccatc
     7681 attgccgttg cagttatttg gttcatgctc aagaaaacaa ctcttggttt tgaaatccgt
     7741 gcagttggtc ttaatccaca tgcttcagaa tatgctggta tttctgccaa gcggactatt
     7801 atcctatcta tgattatttc aggtgccttg gcaggtcttg gtggagctgt tgaaggtttg
     7861 ggaaccttcc agaacgtcta tgttcaaggt tcgtcattag ctatcggatt taacggaatg
     7921 gcggttagtt tgcttgcggc caactcacca attggtatac tctttgcagc cttcctattt
     7981 ggcgttctcc aagttggggc tcctggtatg aatgcggcgc aggtaccatc tgagcttgtc
     8041 agcattgtaa cagcgtctat tatcttcttt gtcagtgttc attaccttat cgaacgcttt
     8101 gtcaaaccga aaaaacaagt taaaggaggt aagtaaagat gtctattata accttgctcc
     8161 ccctcttggt gtcttctatg ctgatttact cagcacctct catctttaca agtatcggtg
     8221 gtgttttctc tgaacgtggt ggtgtggtaa acgttggcct tgaaggaatt atggttatgg
     8281 gtgccttttc tggagttgtc tttaaccttg aatttgcaga acaatttgga gcagcaactc
     8341 catggctatc cttgcttgta gcaggattgg ttggtagtgt tttctctatc atccacgcag
     8401 cagcgacggt tcatttccgt gcagaccatg ttgtcagcgg tacggtattg aacttgatgg
     8461 cgcctgcctt ggctgttttc ttagttaaag ttctttataa caaaggacaa accgacaacc
     8521 taagtcaaac ttttggacgc tttgatttcc cagtcttggc aaatatccca gtgattggtg
     8581 atatcttctt caagtcaact agtctacttg gttatctggc gattgccttc tcattccttg
     8641 cttggtttat tctctttaag actcaatttg gtcttcgtct ccgctctgtc ggtgaacatc
     8701 ctcaagcagc ggataccttg ggaatcaacg tctacaagat gagatattta gggattatta
     8761 tttcaggttt tctaggtgga attggcggag cgatttatgc gcaatcaatc tcagttaact
     8821 tctcagtgac aactattgtt ggacctggat ttatcgccct tgctgcgatg atctttggga
     8881 aatggaatcc aatcggtgct atgctttcta gtctcttctt tggactttca caaagtttgg
     8941 ctgttatcgg ttctcaattg ccgttcctac aaggagtgcc agcggtttat cttcaaattg
     9001 caccttatgt tttgacaatt cttgtcttag cagccttctt tggaaaagca gtcgcaccaa
     9061 aagcagatgg tatcaactac atcaaatcaa aataagcata caaaaaaacg tcagtccaat
     9121 gactgaactg ccccccaaaa gttagacaga aaaaatctaa cttttggggt g
//
LOCUS       DAVBBO010000070         9136 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ST1
            SAMEA2066453-rid20184263.denovo.070, whole genome shotgun sequence.
ACCESSION   DAVBBO010000070 DAVBBO010000000
VERSION     DAVBBO010000070.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2066453
            Sequence Read Archive: ERR351777
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 9136)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9136)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980402.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980402.1
            Genome Coverage       :: 176x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:17:33
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,141
            CDSs (total)                      :: 2,104
            Genes (coding)                    :: 1,953
            CDSs (with protein)               :: 1,953
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 16S)
            partial rRNAs                     :: 1 (23S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 151
            CDSs (without protein)            :: 151
            Pseudo Genes (ambiguous residues) :: 0 of 151
            Pseudo Genes (frameshifted)       :: 73 of 151
            Pseudo Genes (incomplete)         :: 76 of 151
            Pseudo Genes (internal stop)      :: 40 of 151
            Pseudo Genes (multiple problems)  :: 32 of 151
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9136
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2066453-rid20184263.denovo.070"
                     /strain="ST1"
                     /db_xref="taxon:1313"
     gene            1..294
                     /locus_tag="VQU30_001935"
                     /pseudo
     CDS             1..294
                     /locus_tag="VQU30_001935"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466308.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
     gene            370..819
                     /locus_tag="VQU30_001936"
     CDS             370..819
                     /locus_tag="VQU30_001936"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000337416.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HET2447984.1"
                     /translation="MCTILVSIYYKIGLSSSGVYKAVADGEMTVSLSYEDPAVKLLND
                     GANIKVVYPKEGTVFLPASAAIVKKSKNMENAKKFIDFIISQEVQDTLGTTTTNRPVR
                     KNAKTSENMKPIDKIKTLTEDYDYVIKNKSDIVKKYNEVFTDIQSKQ"
     gene            832..1491
                     /locus_tag="VQU30_001937"
     CDS             832..1491
                     /locus_tag="VQU30_001937"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET2447985.1"
                     /translation="MSEIEIINAKKIYHDVPVIENLNITIPKGSLFTLLGASGCGKTT
                     LLRMIAGFNSIEGGEFYFDDTKINNMEPSKRNIGMVFQNYAIFPHLTVRDNVAFGLMQ
                     KKVPKEELIQQTNKYLELMQIAQYADRKPDKLSGGQQQRVTLACALAVNPSVLLMDEP
                     LSNLEAKLRLDMRQAIREIQHEVGITTVYVTHDQEEAMAISDQIAVMKDGVIQQIGRP
                     K"
     gene            1618..1923
                     /locus_tag="VQU30_001938"
                     /pseudo
     CDS             1618..1923
                     /locus_tag="VQU30_001938"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809465.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="TOBE domain-containing protein"
     gene            1913..3558
                     /locus_tag="VQU30_001939"
                     /pseudo
     CDS             1913..3558
                     /locus_tag="VQU30_001939"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520796.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="iron ABC transporter permease"
     gene            complement(3661..4353)
                     /locus_tag="VQU30_001940"
     CDS             complement(3661..4353)
                     /locus_tag="VQU30_001940"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HET2447986.1"
                     /translation="MVKVRLYLVRHGKTMFNTIGRAQGWSDTPLTAEGERGIQELGIG
                     LRESDLQFERAYSSDSGRTIQTMGIILEELGLQGKIPYRMDKRIREWCFGSFDGAYDG
                     DLFMGIIPRIFNVDHVHQLSYAELAEGLVEVDTAGWAEGWEKLSGRIKEGFEMIAKEM
                     EDQGGGNALVVSHGMTIGTIVYLINGMHPHGLDNGSVTILEYEDGQFRVEVVGDRSYR
                     ELGCEKMEEGSI"
     gene            complement(4597..5934)
                     /locus_tag="VQU30_001941"
     CDS             complement(4597..5934)
                     /locus_tag="VQU30_001941"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018166727.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PFL family protein"
                     /protein_id="HET2447987.1"
                     /translation="MDIRQVTETIAMIEEQNFDIRTITMGISLLDCIDPDINRAAEKI
                     YQKITTKAANLVAVGDEIAAELGIPIVNKRVSVTPISLIGAATDATDYVVLAKALDKA
                     AKEIGVDFIGGFSALVQKGYQKGDEILINSIPRALTETDKVCSSVNIGSTKSGINMTA
                     VADMGRIIKETANLSDMGAAKLVVFANAVEDNPFMAGAFHGVGEADVIINVGVSGPGV
                     VKRALEKVRGQSFDVVAETVKKTAFKITRIGQLVGQMASERLGVEFGIVDLSLAPTPA
                     IGDSVARVLEEMGLETVGTHGTTVALALLNDQVKKGGVMACNQVGGLSGAFIPVSEDE
                     GMIAAVQNGSLNLEKLEAMTAICSVGLDMIAIPEDTPAETIAAMIADEAAIGVINMKT
                     TAVRIIPKGREGDMIEFGGLLGTAPVMKVNGASSVDFISRGGQIPAPIHSFKN"
     gene            complement(5944..6210)
                     /locus_tag="VQU30_001942"
     CDS             complement(5944..6210)
                     /locus_tag="VQU30_001942"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002905356.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ACT domain-containing protein"
                     /protein_id="HET2447988.1"
                     /translation="MKAIITVVGKDKSGIVAGVSGKIAELGLNIDDISQTVLDEYFTM
                     MAVVSSDEKQDFTYLRNEFEAFGQTLNVKINIQSAAIFEAMYNI"
     gene            complement(6475..6861)
                     /gene="rplQ"
                     /locus_tag="VQU30_001943"
     CDS             complement(6475..6861)
                     /gene="rplQ"
                     /locus_tag="VQU30_001943"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002887523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L17"
                     /protein_id="HET2447989.1"
                     /translation="MAYRKLGRTSSQRKAMLRDLTTDLLINESIVTTEARAKEIRKTV
                     EKMITLGKRGDLHARRQAAAFVRNEIASENYDEATDKYTSTTALQKLFSEIAPRYAER
                     NGGYTRILKTEPRRGDAAPMAIIELV"
     gene            complement(6873..7808)
                     /locus_tag="VQU30_001944"
     CDS             complement(6873..7808)
                     /locus_tag="VQU30_001944"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000568977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit alpha"
                     /protein_id="HET2447990.1"
                     /translation="MIEFEKPNITKIDENKDYGKFVIEPLERGYGTTLGNSLRRVLLA
                     SLPGAAVTSINIDGVLHEFDTVPGVREDVMQIILNIKGIAVKSYVEDEKIIELDVEGP
                     AEVTAGDILTDSDIEIVNPDHYLFTIGEGSSLKATMTVNSGRGYVPADENKKDNAPVG
                     TLAVDSIYTPVTKVNYQVEPARVGSNDGFDKLTLEILTNGTIIPEDALGLSARILTEH
                     LDLFTNLTEIAKSTEVMKEADTESDDRILDRTIEELDLSVRSYNCLKRAGINTVHDLT
                     EKSEAEMMKVRNLGRKSLEEVKLKLIDLGLGLKDK"
     gene            complement(7851..8234)
                     /gene="rpsK"
                     /locus_tag="VQU30_001945"
     CDS             complement(7851..8234)
                     /gene="rpsK"
                     /locus_tag="VQU30_001945"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003130556.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S11"
                     /protein_id="HET2447991.1"
                     /translation="MAKPTRKRRVKKNIESGIAHIHATFNNTIVMITDVHGNAIAWSS
                     AGALGFKGSRKSTPFAAQMASEAAAKSAQEHGLKSVEVTVKGPGSGRESAIRALAAAG
                     LEVTAIRDVTPVPHNGARPPKRRRV"
     gene            complement(8252..8617)
                     /gene="rpsM"
                     /locus_tag="VQU30_001946"
     CDS             complement(8252..8617)
                     /gene="rpsM"
                     /locus_tag="VQU30_001946"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008809894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S13"
                     /protein_id="HET2447992.1"
                     /translation="MARIAGVDIPNDKRVVISLTYVYGIGLATSKKILAAAGISEDVR
                     VRDLTSDQEDAIRREVDAIKVEGDLRREVNLNIKRLMEIGSYRGIRHRRGLPVRGQNT
                     KNNARTRKGKAVAIAGKKK"
     gene            complement(8635..8751)
                     /gene="rpmJ"
                     /locus_tag="VQU30_001947"
     CDS             complement(8635..8751)
                     /gene="rpmJ"
                     /locus_tag="VQU30_001947"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013773089.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L36"
                     /protein_id="HET2447993.1"
                     /translation="MKVRPSVKPICEYCKVIRRNGRVMVICPANPKHKQRQG"
     gene            complement(8776..8994)
                     /gene="infA"
                     /locus_tag="VQU30_001948"
     CDS             complement(8776..8994)
                     /gene="infA"
                     /locus_tag="VQU30_001948"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003130554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-1"
                     /protein_id="HET2447994.1"
                     /translation="MAKDDVIEVEGKVVDTMPNAMFTVELENGHQILATVSGKIRKNY
                     IRILAGDRVTVEMSPYDLTRGRITYRFK"
BASE COUNT         2766 a         2045 c         1567 g         2758 t
ORIGIN      
        1 tcaaaagaaa atgataatgt tatcaaagaa tatcaaaaca caactggctt ctctactcct
       61 tatacactag atggtagtgt tttaatcgtc caccctgatt taactaaagg catgaacatc
      121 gaaggatata gcgaccttct caaacctgaa ctaaaaggaa aaatcgcaac tgctgaccca
      181 gcaaactctt ctagcgcctt tgctcaatta acaaatatgc tacaagctca aggtggttac
      241 aaagatgata aggcttggtc ttatgtaaaa gatcttttca cacttattga tggtatagta
      301 aaatgaaata agaacaggac aaattaatca ggacagtcaa atcgatttct aacaatgttt
      361 tagaagtaga tgtgtactat tctagtttca atatactata aaatcggttt aagttcatct
      421 ggtgtctata aagcagtcgc tgatggagaa atgactgtta gtctctctta tgaagatcca
      481 gcagttaaac tcttaaatga cggagctaac attaaggtag tctatccaaa agaaggaacc
      541 gtcttcctac ctgctagtgc tgctatcgtt aaaaaatcta aaaatatgga aaatgccaag
      601 aaatttatcg attttattat ctctcaagaa gtacaagata cacttggtac aaccactact
      661 aaccgtcctg ttcgtaaaaa tgctaaaaca agcgaaaaca tgaaaccaat tgacaaaatc
      721 aaaacactca ctgaagatta tgattatgtc atcaagaata aatcagatat cgttaagaaa
      781 tacaacgaag tctttacaga tatccaatct aaacagtaaa agaggttcac tatgagtgag
      841 atcgaaatta ttaacgccaa aaaaatctac cacgatgtcc ctgttattga gaatttgaac
      901 attacaattc caaaaggaag tctctttacc cttcttggag cttcaggatg tgggaaaacg
      961 acccttcttc gtatgattgc aggtttcaac agtatcgaag gtggagaatt ttacttcgat
     1021 gatacaaaaa tcaataatat ggaacccagc aaacgcaata tcgggatggt tttccaaaac
     1081 tacgctattt tcccacattt gactgtccga gacaacgttg cttttggtct tatgcaaaag
     1141 aaggttccaa aagaagaatt gattcaacag accaacaagt atcttgaact catgcaaatt
     1201 gctcaatatg cggatcgaaa gcccgataaa ctcagtggtg gacaacaaca acgtgtcacc
     1261 ttggcatgcg ccttagcggt taatccaagt gttctcctca tggacgagcc acttagtaat
     1321 ctggaggcca aacttcgctt ggatatgcgt caagccatcc gagaaatcca acacgaagtg
     1381 ggaattacaa ctgtttatgt aacccacgac caagaagaag ccatggctat ttcagaccaa
     1441 attgctgtta tgaaagatgg ggtgatccaa caaatcggcc gaccaaaata actctatcat
     1501 aaaccagcta atgagtttgt ggcaaccttt atcggacgca caaatattat ccctgccaat
     1561 cttgaaaaac ggagcgacgg cgcttatatc gtcttttcag atggctatgc ccttcgaatg
     1621 ccagctcttg atcaggttga ggagcaagct attcatgtaa gcattcgtcc cgaagagttt
     1681 atcaaagatg aatctggaga tatcgaagga actattagcg atagcgtcta tcttggacta
     1741 aatacggagt atttcattga gacaggtttt gcctcaaaaa tttaagttag tgaagaatca
     1801 acttttgaag aagaactaca aaaaggcaat cgtattcgtc tacgaatcaa tacgcaaaaa
     1861 ttaaacatct tttctgcaga tggttcccaa aacctgataa aaggagtcaa ccatggaatg
     1921 taaaaaacta aatatttgga cagcttcctc tttcttcatc tttcttacct atcttgtctt
     1981 tctcgtttat cctatcgtta ccgtgctcaa gcaagcactt atacatgaag gacaattctc
     2041 actagctaat tttgtcactt tctttagtaa agcctactac tctgagacac tagtcaacag
     2101 tttcaaggtt tccattaccg ctactatcac ttccttagtt gtaggaaccc tattagctta
     2161 tctcttctct atgtatgact tcaaggggaa gaaatttcta caaatattga ttatcattgc
     2221 ttccatgtca gctcctttcg taggagccta ctcctgaatt ctcttgctgg gacgaaatga
     2281 ggtcatcact aaatttttga caaatgccct tcatcttcca gctatcgata tttatggatt
     2341 caaaggaatt gtacttgtct ttacactgca actattccca ctggtatttc tatatgttgc
     2401 tggaacaatg aacagtattg acaattctct acttgaagca gctgaaagca tggggtcctt
     2461 cggatttaag cgtatcgtaa cggttgtttt acctctccta gttccaacct tactagcagc
     2521 tccttgcttg tatttatgag agcattctca gactttggaa cgcctatgtt gattgacgaa
     2581 ggatatcgga ctttccctgt cctgatttat acccaattta ttagcgaggt tggaggaaat
     2641 tctgcttttg caattatggc gattatcatt gccttggcaa ttttccttat ccaaaaacac
     2701 attgcaaacc gctacagttt cagcatgaat ctgctccatc caattgagcc taaaaaaact
     2761 acaaaaggaa aaatagctgc catttatgca acagtctacg gaattatctt tatctctgtt
     2821 ttacctcaaa tctacttaat ttatacctct ttcctaaaaa catcaggtat ggtatctgtt
     2881 aaaggttatt ctccaaacag ttacaaggta gctttcaatc gtatgggatc tgctattttc
     2941 aataccattc gtatcccttt gattgcctta gttctagttg ttctatttgc gacatttatc
     3001 tcctacctag ccgttagaaa acggaatttg tttacaaact taattgacag cctcagtatg
     3061 gtaccttata ttgtaccagg aaccgttcta gggattgcct tcatttcttc cttcaatact
     3121 ggtctatttg gaagtggatt tcttatgatt acagggactg ctttcatctt gattatgtct
     3181 ctatctgtca gaagattacc ttatactatt cgctcatctg ttgctagctt acaacaaata
     3241 gcaccaagta ttgaagaagc tgctgaaagc ttaggaagta gtcgtctcaa tacctttgct
     3301 aagattacaa ctccaatgat gctatctggt atcatttctg gagccatctt atcttgggtc
     3361 acaatgattt caaaactctc tacttctatc ctcctctaca atgtcaaaac aagaacaatg
     3421 actgtagcta tttatacaga ggttctcaga ggaaattacg gtgtagccgc agccttgtca
     3481 actatcctga ctgttctaac agtaggttcc ttgctcttgt ttatgaaaat ctctaaaagc
     3541 aatagcatta cactttagtt ttccacatca aaaacagccg aaaggagtgc cctcggctgt
     3601 tttttcttat cttgatattc ttatcaaatc cctagctcat ggcaagcaag tctagactga
     3661 ttaaatagag ccttcttcca tcttctcaca tcctagctct cggtaactac ggtcaccgac
     3721 aacttcaacc ctaaactgac cgtcctcata ttcaagaatc gtcacgctac cattatctag
     3781 accatgcgga tgcatgccat taatcagata aacaatggtt ccaatagtca ttccatggct
     3841 gacaacaagg gcgttacctc caccttgatc ttccatttct tttgcaatca tttcaaagcc
     3901 ttccttgatt cggccactga gtttttccca gccttcagcc caaccagctg tatcgacctc
     3961 taccaagccc tcagccagtt cagcataaga caattggtga acgtggtcca cattaaagat
     4021 acgaggaata atgcccatga aaagatcgcc atcataggct ccatcaaaac taccgaaaca
     4081 ccattctctg atacgcttgt ccatgcgata agggattttc ccctgcaagc caagttcttc
     4141 aaggataatt cccatggtct gaatggtacg accagaatca ctcgaataag cgcgctcaaa
     4201 ctgtagatca gattctcgca aaccgattcc taactcttga atccctcgtt caccttcagc
     4261 agttaaggga gtatcgctcc aaccttgcgc gcgaccaatc gtgttaaaca tggtcttgcc
     4321 atgacgtacc aaatacaatc gtacttttac cattttccgt cctccgtttg cttctattat
     4381 atcatgaatg ataaaataaa agccacccat acaggcgact tttgaaggag attattatga
     4441 aaaagtttag gagttcatta aataaagata ttagatgaaa atcaaattca aactaattca
     4501 gtgttatctg tttcaaataa tattaggagg tctttattta atgattatag tatacacatc
     4561 taatcttaaa tagaacttaa aatttctcct attttcttaa tttttaaaac tatgaattgg
     4621 tgctgggatt tgtccaccgc gagagatgaa gtcgacagac gaagccccat taaccttcat
     4681 aacaggtgca gttcctaata gaccaccaaa ctcaatcata tcgccttctc ttcctttggg
     4741 aatgatacga acagctgttg ttttcatgtt gataacaccg attgctgctt catccgcaat
     4801 catagccgca atggtttcag caggcgtatc ttctgggatg gcaatcatat ccaatccaac
     4861 agaacagata gccgtcatag cttctagttt ttctaaatta agagagccat tttgcactgc
     4921 agcaatcatt ccttcatcct cagaaacagg gataaaggcg ccagataaac caccgacttg
     4981 gttgcaggcc atcactccac cctttttaac ttggtcgttc aagagggcca aggcaaccgt
     5041 cgttccatgc gtgccaactg tttctagccc catttcctca aggacacgtg ccacagagtc
     5101 tccaatcgca ggggttggtg ccaaactcaa gtccacaata ccaaactcca cacccagtct
     5161 ctcactggcc atttgaccaa ccaattgacc gatacgagtg attttaaagg cagttttctt
     5221 aactgtttcg gctactacat caaagctctg tccacgaact ttttccaaag cacgtttcac
     5281 cacaccagga ccagaaactc cgacattgat gataacatct gcttccccaa caccatgaaa
     5341 ggcacccgcc ataaatggat tgtcctcaac agcattagcg aatacaacca acttagccgc
     5401 tcccatatct gaaagatttg ccgtttcctt gataattcgt cccatatctg ccacagccgt
     5461 catattaata ccagacttgg ttgagccgat attgactgac gagcagacct tatccgtctc
     5521 agtcaaagcg cgaggaatgg aattgatgag aatctcatct cccttttgat aacctttttg
     5581 tactaaggca gaaaaaccac caataaagtc cacaccaatc tctttcgcag ccttatcaag
     5641 cgcttttgcc agaaccacgt agtccgtcgc atctgtcgct gccccaatca gagaaatagg
     5701 tgtcaccgat acacgcttat taacgatagg aattcccaac tcagccgcaa tttcatcacc
     5761 aacagctact aaattagccg cctttgtcgt aattttttga tagattttct ccgcagcacg
     5821 attgatatct ggatcgatac agtccaaaag agaaatcccc atggtaatgg ttctaatatc
     5881 gaagttttgc tcctcaatca tggcgatggt ttcagtaact tgtctaatat ccatgatgac
     5941 ctcctagata ttatacatag cttcgaaaat cgctgcactc tgaatattga tttttacatt
     6001 caaagtttgc ccaaaagctt caaattcatt acgaagatag gtaaaatctt gcttttcatc
     6061 actagataca acagccatca tcgtaaaata ttcatccaag acagtttgag agatatcgtc
     6121 aatattcaat cctaattctg caattttacc agaaacacct gcaacaattc cagatttatc
     6181 tttaccaaca acagttataa tggctttcat aagtaaactc caattcttct taaaataaga
     6241 aaccttaaca ttaaacagga ttcttttcaa atagtatagc ataattctaa cgaaaatact
     6301 caaaaacgcc tgcttacgaa gttgttctta agaaaaaaac aatttcgtaa acaagcgtct
     6361 actatcccaa cttatgatga gtgttcccgc taggaccgaa atcctagcgg tagaccagag
     6421 ctagactaag agcacaagac tccatcatca taacactcaa caaaattgat gattttatac
     6481 taattcgatg atcgccattg gcgctgcatc accacgacgt ggttcagttt taaggatacg
     6541 agtgtatcca ccgttacgtt cagcataacg aggtgcgatt tctgagaaca atttttgaag
     6601 tgctgtagta gaagtgtact tatcagttgc ttcatcatag ttttcagatg cgatttcatt
     6661 acgtacgaaa gcagctgctt gacgacgtgc atgcaaatca ccacgtttac ctagagtaat
     6721 cattttttca acagttttac ggatttcttt agcacgagct tcagttgtca cgattgattc
     6781 gttgatcaaa aggtcagttg tcaaatcgcg aagcattgct ttacgttgtg agctagtgcg
     6841 tcctagttta cggtaagcca tgtattcctc ctttatttat cttttaatcc aagacccaaa
     6901 tcaatgagtt tgagtttcac ttcttccaaa ctcttgcgtc caagatttcg tactttcatc
     6961 atctctgctt cagatttttc tgtcaaatca tgcacagtat tgataccggc acgttttaaa
     7021 cagttgtatg aacgcacaga caagtccagt tcctcaatcg tacgatctaa aatacggtcg
     7081 tcagattcag tatcagcttc tttcatcact tcagttgact tagcaatctc agtaagattt
     7141 gtaaacaaat caagatgttc tgtcaaaata cgtgctgaaa gccctaaagc atcttctgga
     7201 ataattgttc catttgtcaa gatttcaagg gttaatttgt cgaaaccatc attgctacct
     7261 acacgagcag gttccacttg atagttgact tttgtaactg gtgtataaat agaatctaca
     7321 gcaagtgttc caactggtgc attatccttt ttattttcat cagcaggtac atatccacga
     7381 ccactgttaa cagtcatagt cgcttttaga gaagaacctt caccaattgt aaagagataa
     7441 tgatctggat ttacaatttc aatatcgcta tctgtcaaaa tgtcaccagc cgttacttca
     7501 gcaggacctt caacatccag ttcgatgatt ttttcgtctt caacgtacga tttcactgca
     7561 attcctttaa tgttcagaat gatttgcatc acgtcttcac gaacacctgg aactgtgtca
     7621 aactcatgta acacaccatc aatgttgata gatgtcacag ctgctcctgg tagagaagct
     7681 agaagtacac gacgaagaga gttaccaaga gttgtaccgt agccacgttc aagtggttcg
     7741 attacaaact tgccataatc tttattttca tcaatttttg ttatatttgg tttttcaaac
     7801 tcgatcattt agttactccc tcttaaacga aaagcagtgt aatgcgatga ttatacacgg
     7861 cgacgttttg gaggacgagc accattgtgt ggcactggag tcacatcacg aattgctgtt
     7921 acttcaagac cagcggcagc aagcgcacga atagctgact cacgaccaga acctggacct
     7981 tttacagtaa cttcaactga tttaagaccg tgttcttgtg cagatttagc agcagcttca
     8041 gaagccattt gagcagcgaa tggtgtagat ttacgagaac ctttgaaacc aagagcacca
     8101 gctgatgacc aagcaattgc attaccatgc acatcagtaa tcataacaat agtgttatta
     8161 aatgtagcgt gaatatgagc aataccagat tcgatattct ttttcacacg acgtttacgt
     8221 gttggtttag ccaagacttt tacctcctat attatttttt cttaccagca atcgcaacag
     8281 ctttaccttt acgagtgcga gcgttgtttt tagtattttg tccacggaca ggaagtccac
     8341 gacggtgacg gataccacgg tatgaaccga tttccatcaa acgtttgatg ttcaagttta
     8401 cttcacgacg aaggtcacct tcaactttga ttgcatccac ttcacgacgg atagcatctt
     8461 cttgatctga tgtaagatca cgtacacgaa catcttctga gattccagca gcagccaaaa
     8521 ttttcttaga tgttgcaagt ccgataccat aaacataagt caatgagatt actacgcgtt
     8581 tgtcatttgg aatatcaact ccagcaatac gagccatgtt ttctcctttc tatcttatcc
     8641 ttgacgttgt ttgtgttttg gatttgctgg gcaaattacc ataacacgac cattacgacg
     8701 aataacttta cagtattcgc aaattggttt gaccgatggt cttactttca tttcttatcc
     8761 ctccaagttt ttcgattatt taaagcggta agtgatacgt ccacgtgtca agtcatatgg
     8821 actcatttcg acagtaacac gatctcccgc taaaatacga atatagtttt tacgaatttt
     8881 accagaaact gttgctaaaa tctgatgtcc attttcaagt tcaaccgtaa acattgcatt
     8941 cggcattgta tcaactactt tgccttcaac ttcaatcaca tcgtcttttg ccacgcaaaa
     9001 gcacctccat aaatttcgat tcgatgcctc tagacacaga gacaacaatt ataagtcaga
     9061 ctatctcagt ataacatttg tagcggattt ttgcaagtgc gaaaaacgct ttatttcaaa
     9121 tttgtcaata cttttt
//
LOCUS       DAVBBO010000071         9026 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ST1
            SAMEA2066453-rid20184263.denovo.071, whole genome shotgun sequence.
ACCESSION   DAVBBO010000071 DAVBBO010000000
VERSION     DAVBBO010000071.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2066453
            Sequence Read Archive: ERR351777
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 9026)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9026)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980402.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980402.1
            Genome Coverage       :: 176x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:17:33
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,141
            CDSs (total)                      :: 2,104
            Genes (coding)                    :: 1,953
            CDSs (with protein)               :: 1,953
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 16S)
            partial rRNAs                     :: 1 (23S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 151
            CDSs (without protein)            :: 151
            Pseudo Genes (ambiguous residues) :: 0 of 151
            Pseudo Genes (frameshifted)       :: 73 of 151
            Pseudo Genes (incomplete)         :: 76 of 151
            Pseudo Genes (internal stop)      :: 40 of 151
            Pseudo Genes (multiple problems)  :: 32 of 151
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9026
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2066453-rid20184263.denovo.071"
                     /strain="ST1"
                     /db_xref="taxon:1313"
     gene            complement(135..1103)
                     /locus_tag="VQU30_001949"
     CDS             complement(135..1103)
                     /locus_tag="VQU30_001949"
                     /EC_number="2.7.6.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006149122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribose-phosphate diphosphokinase"
                     /protein_id="HET2447995.1"
                     /translation="MSFSDLKLFALSSNKELAERVAQEIGIELGKSSVRQFSDGEIQV
                     NIEESIRGKHVFILQSTSSPVNDNLLEILIMVDALKRASAESVNVVMPYYGYARQDRK
                     ARAREPITSKLVANMLEVAGVDRLLTIDLHAAQIQGFFDIPVDHLMGAPLIADYFERR
                     GMVGSDYVVVSPDHGGVTRARKLAEFLKTSIAIIDKRRSVDKMNTSEVMNIIGKVEGK
                     TCILIDDMIDTAGTICHAADALAEAGAVEVYASCTHPVLSGPATDNIQKSAIKKLVVL
                     DTIYLPEERLIDKIEQISIAHLLGDAIVRIHEKRPLSPLFDIEKKI"
     gene            complement(1248..2063)
                     /locus_tag="VQU30_001950"
     CDS             complement(1248..2063)
                     /locus_tag="VQU30_001950"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000749763.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PrsW family intramembrane metalloprotease"
                     /protein_id="HET2447996.1"
                     /translation="MKKSSILFIFILLLCIGLQYETIYYTDGSRSGAEYGLMGVSIFL
                     ALFYMIPALYFLFRIGKKWELPKKVLILSLLGGMFLSGWLSSFTNTYIHDLLGVLFPD
                     SPFLNAFESAIVAPLVEEPLKLLPLVFVLALIPVRKLKSLFLLGIASGLGFQMIEDIG
                     YIRTDLPEGFDFTISRILERIISGIASHWTFSGLAVVGVYLLYRAHKEQKVGKKQGLI
                     FLGLALRTHFLFNSPFVELETELPLAIPVVTAIALYGFYHAYCFVEKHNELMT"
     gene            complement(2088..2585)
                     /locus_tag="VQU30_001951"
     CDS             complement(2088..2585)
                     /locus_tag="VQU30_001951"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007285146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbonic anhydrase"
                     /protein_id="HET2447997.1"
                     /translation="MSYFEQFMQANQAYVALHGQLNLPLKPKTRVAIVTCMDSRLHVA
                     QALGLALGDAHILRNAGGRVTEDMIRSLVISQQQMGTREIVVLHHTDCGAQTFENEPF
                     QEYLKEELGVDVSDQDFLPFQDIEESVREDMQLLIESPLIPDDVIISGAIYNVDTGSM
                     TVVEL"
     gene            complement(2658..4019)
                     /gene="radA"
                     /locus_tag="VQU30_001952"
     CDS             complement(2658..4019)
                     /gene="radA"
                     /locus_tag="VQU30_001952"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000336571.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RadA"
                     /protein_id="HET2447998.1"
                     /translation="MAKKKATFVCQNCGYNSPKYLGRCPNCGSWSSFVEEVEVAEVKN
                     ARVSLTGEKTKPMKLAEVTSINVNRTKTEMEEFNRVLGGGVVPGSLVLIGGDPGIGKS
                     TLLLQVSTQLSQVGTVLYVSGEESAQQIKLRAERLGDIDSEFYLYAETNMQSVRAEVE
                     RIQPDFLIIDSIQTIMSPEISGVQGSVSQVREVTAELMQLAKTNNIAIFIVGHVTKEG
                     TLAGPRMLEHMVDTVLYFEGERHHTFRILRAVKNRFGSTNEIGIFEMQSGGLVEVLNP
                     SQVFLEERLDGATGSSIVVTMEGTRPILAEVQALVTPTMFGNAKRTTTGLDFNRASLI
                     MSVLEKRAGLLLQNQDAYLKSAGGVKLDEPAIDLAVAVAIASSYKDKPTNPQECFVGE
                     LGLTGEIRRVNRIEQRINEAAKLGFTKIYVPKNSLTGITLPKEIQVIGVTTIQEVLKK
                     VFA"
     gene            complement(4033..4548)
                     /locus_tag="VQU30_001953"
     CDS             complement(4033..4548)
                     /locus_tag="VQU30_001953"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000691237.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HET2447999.1"
                     /translation="MKIIFVRHGEPDYRELEERSYIGFGIDLAPLSEMGRQQVQKLSK
                     NPLLSSAEIIVSSAVTRALETASYVVCATGFPLRVEPLLHEWQVYKTGIENFETARRL
                     FLENKGELLPNSPIQYETATEMKSRFLECMSKYREHQTVVVVAHRMLMRQFVPNEKID
                     FCQVIECELEI"
     gene            complement(4550..4993)
                     /locus_tag="VQU30_001954"
     CDS             complement(4550..4993)
                     /locus_tag="VQU30_001954"
                     /EC_number="3.6.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000701981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dUTP diphosphatase"
                     /protein_id="HET2448000.1"
                     /translation="MKIRGFELVSSFTDENLLPKRETAHAAGYDLKVAVRTVVAPGEI
                     VLVPTGVKAYMQPTEVLYLYDRSSNPRKKGLVLINSVGVIDGDYYGNPGNEGHIFAQM
                     KNITDQEVVLEVGERIVQAVFATFLIADGDAADGVRTGGFGSTGH"
     gene            complement(5050..5147)
                     /gene="ffs"
                     /locus_tag="VQU30_001955"
     ncRNA           complement(5050..5147)
                     /ncRNA_class="SRP_RNA"
                     /gene="ffs"
                     /locus_tag="VQU30_001955"
                     /product="signal recognition particle sRNA small type"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00169"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00169"
     gene            complement(5180..5647)
                     /locus_tag="VQU30_001956"
     CDS             complement(5180..5647)
                     /locus_tag="VQU30_001956"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside deaminase"
                     /protein_id="HET2448001.1"
                     /translation="MYYTLEEKEVFMREALREAEIALEHDEIPIGCVIVKDGEIIGRG
                     HNAREELQRAVMHAEIMAIEDANLSEESWRLLDCTLFVTIEPCVMCSGAIGLARIPNV
                     VYGAKNQKFGAAGSLYDILTDERLNHRVEVEIGILEDECAAIMQDFFRNRRKK"
     gene            complement(5848..7134)
                     /locus_tag="VQU30_001957"
     CDS             complement(5848..7134)
                     /locus_tag="VQU30_001957"
                     /EC_number="6.3.4.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017279.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenylosuccinate synthase"
                     /protein_id="HET2448002.1"
                     /translation="MTSVVVVGTQWGDEGKGKITDFLSANAEVIARYQGGDNAGHTIV
                     IDGKKFKLHLIPSGIFFPEKISVIGNGMVVNPKSLVKELSYLHEEGVTTDNLRISDRA
                     HVILPYHIELDRLQEEAKGDNKIGTTIKGIGPAYMDKAARVGIRIADLLDKDIFRERL
                     ERNLAEKNRLFEKLYDSKAIVFDDIFEEYYEYGQQIKKYVIDTSVILNDALDNGKRVL
                     FEGAQGVMLDIDQGTYPFVTSSNPVAGGVTIGSGIGPSKIDKVVGVCKAYTSRVGDGP
                     FPTELFDEVGERIREVGHEYGTTTGRPRRVGWFDSVVMRHSRRVSGITNLSLNSIDVL
                     SGLDTVKICVAYDLDGQRIDYYPASLEQLKRCKPIYEELPGWSEDITGARNLEDLPEN
                     ARNYVRRVSELVGVRISTFSVGPGREQTNILESVWS"
     gene            complement(7365..7601)
                     /locus_tag="VQU30_001958"
     CDS             complement(7365..7601)
                     /locus_tag="VQU30_001958"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001846364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase RecX"
                     /protein_id="HET2448003.1"
                     /translation="MLQKIYEQMTNFYDSIEEEYGPTFGDNFDWEHVHFKFLIYYLVR
                     YGIGCRRDFIVYHYRVAYRLYLEKLVMNRGFISC"
     gene            7867..8664
                     /locus_tag="VQU30_001959"
                     /pseudo
     CDS             7867..8664
                     /locus_tag="VQU30_001959"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000436304.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing N-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(8699..>9026)
                     /locus_tag="VQU30_001960"
     CDS             complement(8699..>9026)
                     /locus_tag="VQU30_001960"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HET2448004.1"
                     /translation="LTNGELIAPMTYEEMVTSDFFEAWFQKFLLPTLTTPSVIIMDNA
                     RFHRMGKLELLCEEFGHKLLPLPPYSPEYNPIEKTWAYIKKNLKKVLPSCNTFYEALF
                     SCSCFN"
BASE COUNT         2893 a         2145 c         1455 g         2533 t
ORIGIN      
        1 tgatgacgta cagtcatatt tcttctcttt ttattatatc acagttttaa atctagcttt
       61 actagattca ccgctactat ctatttattc ggaaaaaaga cgaaaaaacc tgagaatcat
      121 ctcaggcttg gtcattaaat ttttttctca atatcgaaaa gtggagaaag tggtcgtttt
      181 tcatgaatac gtacgatagc atcccctagg agatgagcga ttgaaatctg ctcaatctta
      241 tcaatcaaac gctcttctgg cagatagatg gtatccaaaa caaccaattt cttaatagct
      301 gatttttgga tattgtccgt agcaggacca gaaagaactg ggtgcgtaca gcttgcatag
      361 acttcaacag caccagcttc cgcaagagca tctgccgcat gacaaatcgt tccagcggta
      421 tcaatcatat catcaatcaa gatacaagtc ttgccttcaa ccttaccgat gatgttcata
      481 acttcactag tattcatctt atcaacgcta cgacgtttat caataatagc gatagatgtt
      541 ttcaaaaatt ctgccaactt acgagcacga gtcacccctc catggtccgg gctgacaacc
      601 acatagtcag aaccaaccat accacgacgc tcaaaataat ctgcaatcag aggagcaccc
      661 atcaaatgat ccacaggaat atcaaagaat ccttgaattt gcgcagcatg caagtcgatg
      721 gtcaataaac gatccactcc agctacttca agcatatttg cgacaagttt tgaagtgatt
      781 ggctcacgcg ctctcgcctt tctatcctga cgtgcatacc catagtaagg catgacaaca
      841 ttgacagatt ctgcactcgc acgcttcaaa gcatctacca taatcaaaat ttcaagcaga
      901 ttgtcattta caggcgaact agttgattgt aggataaaga cgtgtttccc acggattgat
      961 tcttcaatgt tgacctgaat ctctccatct gaaaattggc gaacacttga tttccccaac
     1021 tctatcccaa tctcctgcgc cacacgttct gccaattctt tattagaaga aagggcaaac
     1081 agctttaaat cagaaaaaga catgatttcc tccggtatat atgtatcgct tgtgcttttc
     1141 acaagatttt ccatctacca ttgtagcgct ttttgcacta tttttcaatc aaaaataaaa
     1201 gaagggcacc atatttgtac ccttgcatca ttcttttgaa aaatattcta ggtcatcaac
     1261 tcattgtgtt tctcaacaaa gcaataagca tgataaaaac catagagagc aatagccgta
     1321 accactggaa tcgctaaagg caactctgtt tccaactcca caaaaggaga gttaaacaag
     1381 aagtgagttc tcaaggctaa acctagaaaa ataaggccct gtttcttgcc aaccttctgt
     1441 tctttatggg ctctgtaaag caagtaaaca cctactacag ctagacctga aaaagtccag
     1501 tgagaggcaa ttcctgagat gatacgctct aaaattcgcg aaatagtaaa gtcaaagccc
     1561 tctggcaaat ccgtacgaat ataaccaata tcctcaatca tttggaatcc caaaccggaa
     1621 gcaattccaa gtaaaaacaa agattttaat tttcgcacag gaatcaaagc caaaacaaaa
     1681 acaagtggca ataatttcaa gggttcttct accaaaggag ccacaatagc actttcaaag
     1741 gcatttaaaa atggactatc tgggaaaaga acccccagta aatcatggat ataagtatta
     1801 gtaaaactag acaaccagcc tgaaaggaac atccctccca ataaagacag aatcaaaacc
     1861 ttctttggca attcccattt tttcccaata cggaagagaa aataaagagc cggaatcatg
     1921 taaaagagag ctagaaagat agaaactccc attagtccat attccgcacc tgacctcgaa
     1981 ccgtccgtat agtagatggt ttcatactgt aaaccaatac atagcaataa aataaaaata
     2041 aataaaatac tgcttttctt catacacttt ctttctaaat gaagtattta taattctacg
     2101 actgtcatac ttcctgtatc aacattgtaa atggcaccag agataatgac atcgtctggt
     2161 attaggggag actcgataag cagttgcata tcctcgcgta cactctcttc tatatcttgg
     2221 aagggcaaga agtcctggtc tgacacatct acacctaatt cctcttttaa atactcctga
     2281 aaaggttcat tttcaaaggt ctgagcacca cagtctgtat ggtgcaatac cacaatctct
     2341 cttgtcccca tttgttgctg ggaaataact agcgaacgaa tcatgtcttc agtcactcga
     2401 ccacctgcat tccgcaagat atgagcatcc ccaagtgcca agcccagagc ttgcgcaacg
     2461 tgcagacgag agtccataca ggtcacaata gctactcttg ttttgggttt aagtggcaga
     2521 tttaactgcc catgtagggc aacataagcc tgattagctt gcataaactg ttcaaaatac
     2581 gacacgattc cctccttgaa aatttgatag tcaaatattt ctcctatctt atcattttta
     2641 agagaatttg tcacggatta tgcaaagacc tttttcaaaa cttcctgaat cgttgtcacg
     2701 ccaatgacct gaatttcctt aggcagagtg attcctgtca aggaattctt aggtacataa
     2761 atcttagtaa agcccagttt agcagcttcg ttgatgcgtt gctcaatacg attcacgcgc
     2821 cgaatctctc ctgtcaagcc cagttctccg acaaaacatt cctgaggatt agttggcttg
     2881 tctttgtagc tcgaagcaat agcaactgca acagccaagt caatggcagg ttcatccaat
     2941 ttaacaccac cagcagattt gagataggca tcctgatttt gcaagagaag ccctgcccgt
     3001 ttttccaaaa cagacataat caagctagca cggttaaaat caagtcctgt cgtagtacgc
     3061 ttggcatttc caaacatggt cggtgttacc aaagcctgaa cctccgccaa aatcggacgc
     3121 gtcccttcca tggttacaac gatggaggaa ccagtcgccc catccaaacg ctcttctagg
     3181 aaaacttgac tcggattgag tacctcaacc aagccgcccg actgcatctc aaaaatccca
     3241 atctcattag tggaaccaaa acgatttttg accgctctca aaatacgaaa ggtgtggtga
     3301 cgctcccctt caaagtaaag caccgtatcc accatatgct ccaacatacg aggcccagcc
     3361 aaggttcctt ctttggtcac atgacctacg ataaagatgg caatgttatt ggtcttggcc
     3421 aactgcatga gttcagcggt cacttcacgc acctgagaaa cagacccctg cacccctgaa
     3481 atctcaggag acatgatggt ctggatggaa tcaataatga gaaagtctgg ctggatacgc
     3541 tccacttctg cacgaacact ctgcatattg gtctctgcat agagataaaa ctcactatca
     3601 atatcaccta agcgctctgc acgtagttta atctgctggg cagactcctc cccactgaca
     3661 tagagaactg tccccacttg ggacaactgg gttgagactt gtaggagaag agttgatttc
     3721 ccaatcccag gatccccacc gatgaggacg agacttcctg gtaccactcc gcctccaagc
     3781 acacggttga attcctccat ctccgtcttg gttcgattga cattgatgga agtcacctca
     3841 gctagtttca tgggcttggt tttctcacct gtcaaggaca cacgcgcatt cttgacctcg
     3901 gcaacctcaa cctcttccac aaaagaagac caagacccac agttggggca acgtcccaga
     3961 tatttagggg aattataccc acaattttga catacaaatg tcgctttttt ctttgcgatg
     4021 acaaacctct ttctatatct ctaactcaca ctcaatcact tggcaaaaat caatcttctc
     4081 atttggcaca aactggcgca tgagcattcg atgagcaaca actaccacag tctgatgttc
     4141 tcgatactta gacatacatt ctagaaaccg agacttcatt tccgtagctg tctcatattg
     4201 aataggacta ttaggaagca actccccctt gttttctaaa aacagtcttc tagctgtttc
     4261 aaagttttct attcctgttt tatagacctg ccattcatgt aataaaggct ctactcttaa
     4321 aggaaaaccc gtagcacata ccacatacga agccgtttct aaagctcttg tgactgcaga
     4381 agatacgatt atttcagctg acgagagtaa aggatttttg ctcaatttct ggacttgctg
     4441 ccgtcccatc tcagacaagg gtgccaaatc tatcccaaat cctatataag aacgctcctc
     4501 taactcacgg taatctggct ccccatgacg tacaaagata atcttcattc tagtgccctg
     4561 tcgatccaaa tccaccagtt cgaacgccat cagccgcatc tccatctgca attaagaaag
     4621 tagcaaaaac agcctggaca atacgctccc caacttcaag aacaacctct tggtctgtga
     4681 tattcttcat ctgcgcaaaa atatgccctt catttccagg atttccataa taatccccat
     4741 caatgactcc aactgagtta attaaaacca agcccttctt acgaggattt gaagaacgat
     4801 catagaggta gagaacctca gtcggctgca tataagcctt aacccctgtc ggaaccaaga
     4861 caatctctcc tggcgcaaca actgtacgca cagcaacctt taagtcgtaa ccagccgcat
     4921 gcgctgtctc acgcttgggc aataaatttt catctgtaaa actcgaaacc aattcaaaac
     4981 cacgaatttt cataattttc tcttttctat tatcatttat tctagattat tctatcttat
     5041 ttattcggaa aaagcacgaa aaaaagagca cacaattcaa atcgcttagg gctgctggat
     5101 tcctcccctg acccgcttca cgcagaactg ttgctccact atttattata tcacattcct
     5161 attcatttta aaagcaaaat tattttttcc gtctatttct aaaaaaatcc tgcatgatag
     5221 ctgcgcattc atcttccaaa attcctattt caacctccac acgatgatta agacgctcat
     5281 ctgtcaagat atcgtacaaa cttccagcag cgccaaattt ctggttttta gccccataga
     5341 ccacatttgg aatgcgggca agcccaatcg ccccactaca catgacacaa ggttcaatgg
     5401 tcacaaaaag tgtgcaatcc agcaagcgcc agctctcctc actcaagttc gcatcctcta
     5461 tagccataat ttccgcatgc ataaccgctc gctgtaattc ctcacgcgca ttatgcccac
     5521 gaccaatgat ttccccatct ttgacaatca cacaaccaat tggaatttca tcgtgttcaa
     5581 gagcaatctc agcctctctc aaagcctccc tcataaagac ttctttttct tcaagcgtat
     5641 aatacatctc ttttctcttt tcctacttat cgattttatt attatatcat gaatcccaac
     5701 acaaaaaaag ccaccgaatg cggtgactct atagggagat tattatgaaa aagaaaagtt
     5761 taggatattt gttacaacaa gttaggaggt cttcttgtaa ctgtctatag tatacccgac
     5821 ctatcttaaa caaatcttaa aaatctctta ggaccaaaca ctttctaaaa tatttgtttg
     5881 ttcacgacca ggacctactg agaaagtaga aatacgaacg ccaaccaatt cactcacacg
     5941 acgaacatag ttacgcgcat tctcaggaag atcttccaaa ttgcgagctc cggtaatatc
     6001 ttctgaccaa cctggcaact cttcatagat aggcttgcaa cgtttcaatt gctcaagact
     6061 agctggatag tagtcaatac gttgaccgtc aagatcatag gccacacaaa ttttcacagt
     6121 atccaagccg ctcaaaacat caatagagtt caaagaaagg ttagtaatac cagaaacacg
     6181 acggctatga cgcatcacaa ctgagtcaaa ccaacctaca cgacgtggac gaccagttgt
     6241 tgtaccatat tcatgaccca cttcacggat acgttctccc acttcatcaa acaactcagt
     6301 tgggaaagga ccatctccta cacgactcgt ataagcttta catacaccta caaccttgtc
     6361 aatcttgctt ggaccgatac cagaaccaat tgtcacacca ccagctacag ggtttgatga
     6421 cgtaacaaat ggataagtac cttgatcgat atctagcata acaccttgtg caccttcaaa
     6481 aagcacacgt ttgccattat caagcgcatc attcaagata acagatgtat ctatcacgta
     6541 tttcttgatt tgttgaccat attcgtaata ttcttcaaaa atatcatcga aaacaatcgc
     6601 tttactgtca tacaattttt caaaaagacg attcttttca gcaaggttac gttctaaacg
     6661 ctcacggaaa atatctttat ctaaaagatc tgcaatacga attccaacac gagcagcctt
     6721 gtccatataa gctggaccaa ttcccttaat tgtcgtacca atcttattgt cgcccttagc
     6781 ttcttcttgc aagcgatcca actcgatatg ataaggcaaa ataacatgcg cacgatcaga
     6841 aatacgcaag ttatcagttg ttacaccttc ctcatgaaga tagctcaact cttttacaag
     6901 agatttagga tttacaacca taccattccc aatgacagat attttttcag ggaagaaaat
     6961 cccagatgga atcaagtgca acttaaattt cttaccgtca atcacaatcg tgtgaccagc
     7021 attatcacca ccttggtaac gtgcaattac ttctgcattc gctgaaagga agtctgtaat
     7081 cttcccttta ccttcatcac cccattgggt acctacaaca acaactgaag tcataatttt
     7141 gtctgagccc tcaggctctt cctttctcac atacatggca ggactctcac ctgcaattat
     7201 atcttacaat ttattataat aaaaaatcgc ctttttatca agaagaaaca atagaaagat
     7261 ttgctatttc caactattaa aaaatgattt agaaaaatta ctagctattt actattatct
     7321 ttccataaaa gagtaaatta gttcggaaat ttactaaaat tacctcaaca agaaataaaa
     7381 ccccgattca ttaccaattt ttcaagatac aaacgataag caacacgata atggtaaacg
     7441 ataaaatccc tacgacaacc aatgccatat ctcactaaat aataaattaa aaatttaaaa
     7501 tgaacatgtt cccagtcaaa attatcacca aatgtaggac catactcttc ttcaatacta
     7561 tcatagaaat tagtcatctg ctcataaatt ttttgtaaca taatcaaata ctccttttct
     7621 tttttataaa cttattctaa caaaaaattt tacacattca ctatcaattc ctgaattgtt
     7681 aaaataccag cctcaacaag ataaaaatag gaaaagttga caaaatagaa acaaatttgc
     7741 tacctaaatt tcaaacgatt aaagttctaa aaagaccgcc ttaaaacttt tgggtaaatc
     7801 ctattagaac tataatattt atatatatgt attatggttc tgattttcta gtataaaaaa
     7861 attcaaacta gaattcttct tagaaaaggc cgttttaagt gctatcattg ctcaaaaatg
     7921 gaggtcgctg agacttctat cgtcaagaag aatcatcaaa ttccttgtat catcaaccaa
     7981 aagattgctc agaagttaat tgaaaagact tctatgaccg acattgatca tcagttgtct
     8041 atttcaactt caactgtcat tcgcaagatc aataattttc actttgagca tgatttttcg
     8101 cgtcttcctg agattatgtc ctaggacgtt gaaacagtcc ggggagtgac tgtttcaatc
     8161 gggagatgga gatgagcttt attgctcagg actttgataa actcaatatc ataactgttc
     8221 ttgagagcag aacacaagcc atcatccgaa atcccatgaa tacaaggcta tcaagcgcta
     8281 ctggaagctc attcaacaag atagtcagaa actgagtgat aaacgatttt atcgccctac
     8341 ttttcgtatg cacttgacta ataaagaaat tctagataaa cttttgagct attccgaaga
     8401 cttgaaacac cactataatc tctatcagct cttgcttttc cacctctgtt tcagactttg
     8461 tttaaaacct tcctcaaaga taaagagaaa atcgtcaacg cccttcaatt accttattcc
     8521 aacgccaaac tggaagccac caataatctc atcaaactta tcaagcacaa tgcctttggt
     8581 tttaggaact ttgaaaactt caaaaaagaa aggacgaaat ttgtcctttc tagatcttcg
     8641 ctttcttcaa cccactacag ttgacaaaga accgaaaaat gtctcgcctc taatatagtc
     8701 aattgaaaca agaacaagag aaaagagcct cgtaaaaggt attgcaactt ggtaatacct
     8761 ttttgaggtt ctttttgata taagcccatg ttttctcaat aggattgtac tcaggtgagt
     8821 agggaggaag aggtaaaagt ttatgcccaa actcctcgca taaaagttct aacttaccca
     8881 ttctatggaa tcttgcatta tccataataa taaccgatgg tgtggttaat gttggtaaga
     8941 gaaacttctg aaaccaagct tcaaaaaagt cgctcgtcac catctcttcg taagtcattg
     9001 gagcgattaa ctcaccattt gttaga
//
LOCUS       DAVBBO010000072         8830 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ST1
            SAMEA2066453-rid20184263.denovo.072, whole genome shotgun sequence.
ACCESSION   DAVBBO010000072 DAVBBO010000000
VERSION     DAVBBO010000072.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2066453
            Sequence Read Archive: ERR351777
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 8830)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8830)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980402.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980402.1
            Genome Coverage       :: 176x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:17:33
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,141
            CDSs (total)                      :: 2,104
            Genes (coding)                    :: 1,953
            CDSs (with protein)               :: 1,953
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 16S)
            partial rRNAs                     :: 1 (23S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 151
            CDSs (without protein)            :: 151
            Pseudo Genes (ambiguous residues) :: 0 of 151
            Pseudo Genes (frameshifted)       :: 73 of 151
            Pseudo Genes (incomplete)         :: 76 of 151
            Pseudo Genes (internal stop)      :: 40 of 151
            Pseudo Genes (multiple problems)  :: 32 of 151
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8830
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2066453-rid20184263.denovo.072"
                     /strain="ST1"
                     /db_xref="taxon:1313"
     gene            264..1322
                     /locus_tag="VQU30_001961"
     CDS             264..1322
                     /locus_tag="VQU30_001961"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001849785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2448005.1"
                     /translation="MKDDQKYLLAGLYSLLVAIFYFPLIESKGIFVSILMAVLLLYLI
                     YFIATVIHIVIIKFIRKKSFKYLVLYPFTYDGSWRFQPINLLYFPEMVRDVIPINLVQ
                     EYCQGQPYGLLKKMLKRIRLSREIALLLATIIVYFFTHRILPLSVFTFIFSYILLFAQ
                     SYLGGNTVWIGNRRLIIDDEFEKILLSKSYIKEISSARYSEYLTCEYKNLTPIILLAI
                     FENLLDSYLLQNQSEVDLDIFYKVLPLLYKEKYTMGFNYFVSLNYLLYKVGFLGIIYD
                     NEALGDLSKQYLNRNISELQDGSFDGGIQDAVASKQIVVINEFIACLNSRCMPSQYDR
                     FFYKDRPYIFSRKSPIKG"
     gene            1637..2611
                     /locus_tag="VQU30_001962"
     CDS             1637..2611
                     /locus_tag="VQU30_001962"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001842000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2448006.1"
                     /translation="MKNKRYFFDTILMILLLISTIFCVSPVFIKLDILGTPSHAILTF
                     VLAIPLFYILSQCLHTLLLLVSSIFCKLRPIYFYFIFVIIIGARKYYRILFHQLMGFS
                     PGIAVFYKESQTTKNLFKFYYFLYFTTLISYYFFFTFVYDKPLLLPLIPFSIIIALVQ
                     KLYRIENQQLFLLKSKVLTILESKKNCEFNLQDYHEIWKLQSKSELPCVALSYISLIK
                     PYLSESVREQIDLLEVKRFKKINHPISLYGMLDVIKLNLYLRHYNEKNKYESMLKKIL
                     EVRPDFVLIEQNIDDSLNSSQPLSLSLAISEIQLLLEVYMGIKHVSTK"
     gene            2991..3365
                     /locus_tag="VQU30_001963"
     CDS             2991..3365
                     /locus_tag="VQU30_001963"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000424474.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SPH_0224 family bacteriocin-like peptide"
                     /protein_id="HET2448007.1"
                     /translation="MELVLPNNYVVLEQEEMMYLDGGFSIPRWPVATAINIAFNGVLG
                     GGAISLVRNYIRNYGLRRVTSAIAGAAARYVGVRVANRVAGFALSAINGFAAWMSIGD
                     AITTIWANNDVNRRDPNLNALW"
     gene            3573..4475
                     /locus_tag="VQU30_001964"
     CDS             3573..4475
                     /locus_tag="VQU30_001964"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000619809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2448008.1"
                     /translation="MIRKLIVFLLMLPLFVLWLELHVLVNNLLLNLESPLDFVISMSL
                     AFCSLILSKIVLDILYALKDLYKKEGLIKIFPFIFIRRKKVNVRFSPYFSFHRKSLSP
                     DDLRSRIIWSFILEIAIILVFILKIPFAIIMLTTIFFWTIMDINHLVFNKTEFLFNQN
                     KWQKEDSFESNLHKILMDKIQKSELSYSDLMSLLLYDAMNQSTFLTDSELFEDILKKI
                     EDSHNTLLCTGLVELLLYEISISNNNNWQEKVDKIRIQLIRINQLDFFYYTSWLRQNF
                     DFCMNREYHKMKSRKLLLSNKKIV"
     gene            4531..4770
                     /locus_tag="VQU30_001965"
     CDS             4531..4770
                     /locus_tag="VQU30_001965"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000424445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="argininosuccinate lyase"
                     /protein_id="HET2448009.1"
                     /translation="MELVLPNNYVVIDEEVMMYLDGGAYLSKRACQGICAAAGVLATA
                     AGKIAYCIGYGVLNRGCDINENPYPWDGFISATVR"
     gene            4767..5495
                     /locus_tag="VQU30_001966"
     CDS             4767..5495
                     /locus_tag="VQU30_001966"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866696.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2448010.1"
                     /translation="MSNVDKIRKIHIIVCWVYIFLSFRAIINDTEYFLLIFLAFIYSI
                     VSLPLYSVKNKIVSICLVINSILLMSFPILINKFFPESFLTYTVLISVFILELAIFHL
                     IRKDFDIKLTNEYKKISQFRSKVSQSPWIKYLEISSFILTIFPSILYGKVDNHVLTLI
                     FLIKICVDTTIKFLFIRLFDTSTLMKRRIFFLFALDVIAYLFLGYLLVIQKAGYLFSV
                     LLLFSNFSVPFIKEKEYELFKNSK"
     gene            6630..6869
                     /locus_tag="VQU30_001967"
     CDS             6630..6869
                     /locus_tag="VQU30_001967"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000770310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2448011.1"
                     /translation="MKLLDCILDYQERFNGKTCQVSTNYKYLEIFKVNFCLTDLHHLF
                     DLYKITRDYASQTKPAIQDGVFILEDFRNILCTMM"
     gene            7419..>8830
                     /locus_tag="VQU30_001968"
     CDS             7419..>8830
                     /locus_tag="VQU30_001968"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001035388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choline-binding protein"
                     /protein_id="HET2448012.1"
                     /translation="MNKKKMILTSLASVAILGAGFVTSQPTFVRAEEAPVASQSKAEK
                     DYDAAVKKYEAAKKEYEDGKAAQKKYEDDQKKTEEKAEEERKASEEEQAANLKYQQEL
                     VKYIRENDPTKKAEAKKAMDEAEKEYKKKQTEFAEVRAKVIPSAEELKKTRQKAEEAK
                     AKEAELTKKVEEAEKKVTEAKQKVDAEHAEEVAPQAKIAELEHEVQKLEKALKEIDES
                     DSEDYVKEGLRAPLQFELDVKQAKLSKLEELSDKIDELDAEIAKLEKDVEDFKNSDGE
                     QAGQYLAAAEEDLVAKKAELEKTEADLKKAVNEPEKPAEETPAPAPKPEQPAEQPKPA
                     PAPQPEKPAEEPENPAPAPQPEKSADQQAEEDYARRSEEEYNRLTQQQPPKAEKPAPA
                     PQPGWKQENGMWYFYNTDGSMATGWLQNNGSWYYLNANGAMATGWLQYNGSWYYLNAN
                     GAMATGWLQYNDSWYYLNANG"
BASE COUNT         3046 a         1215 c         1616 g         2953 t
ORIGIN      
        1 taaatctaat aaattctatt attatagctc ttggtatgat attggcatta attttggtat
       61 tatcaagagt gtatagaaaa tatttttata gagacgatga tgactaaagt ttttatcaat
      121 aatttgggct ccttgtcaac tgtagtggat tgaagaaaag ctaacgtctg gggaagggtt
      181 taaagctttg ctttatcaaa tattgactta cagagttgct ctattgtatt gatgtattct
      241 tagtaaataa tatggtgttt tgaatgaaag atgatcagaa atatttatta gcgggacttt
      301 attcgcttct agttgcaata ttttattttc cattgattga gtccaagggg atttttgtaa
      361 gtatattgat ggcggtttta cttttatatt taatatactt cattgcaaca gtcattcata
      421 ttgtgataat taagtttata agaaaaaaat cttttaagta tttggttcta tatccattta
      481 cttatgatgg gagctggaga tttcaaccta taaacttact ctactttcca gaaatggtga
      541 gagatgtcat tccgattaat ttagttcaag aatattgcca aggacaacct tacggactgt
      601 taaaaaagat gctgaaaaga attcgattgt cacgagagat agctttactc ctggctacca
      661 ttatcgtcta tttttttacg catagaattc tacctctttc agtatttacg ttcatatttt
      721 cttacatatt gctatttgca caatcttatt tgggtggtaa taccgtttgg attggaaata
      781 gaagattaat aatagatgat gaatttgaaa aaatcttgct ttcaaaaagt tatataaaag
      841 aaatatcatc tgcacgatac tcggaatact tgacatgtga atacaaaaac cttacaccaa
      901 tcatattgtt agctattttt gaaaatttgc ttgactccta cttgcttcag aatcagagtg
      961 aggttgactt agatattttt tataaagttt tacctttgct ttataaagaa aaatatacta
     1021 tgggattcaa ttactttgta agtttaaatt atttactata taaggttgga tttttgggaa
     1081 tcatttacga taatgaagca ttaggagatt tgtcaaaaca atatttaaac agaaatattt
     1141 cggaattaca agatggttct ttcgatggcg gtatacaaga tgctgttgcc tctaaacaaa
     1201 tagtagttat aaatgaattt atagcttgtt taaattccag atgcatgcca tcccaatatg
     1261 atagattttt ttataaagat agaccttata ttttttccag aaagagtcct attaaggggt
     1321 gaaaatttgt tacatttgga ttaacaagtg tcctagggat tagaaataac tctagtatag
     1381 ctagatattt ttgagtaact agaaatatca ttaggctacc catatgattg ccagaaaaga
     1441 tggctgatga atcttattta tactgttgca gtaggcattg tctaggataa ataagctatc
     1501 ttgatggggg aaattggaat aattttagta gaaacattaa aggattatgg acaagtagcg
     1561 caggattagg tgatgcaatg tgctaagttg gcttggtgtt agcagtagta ttatttaaca
     1621 atggaaagta gactaaatga aaaataagcg ttattttttt gacacaattt taatgatttt
     1681 actgcttata agcacgatat tttgtgtcag cccagtattt ataaaattgg acatcttagg
     1741 aaccccctct catgccatct taacctttgt attggcgata ccgttattct atattttgtc
     1801 tcaatgctta catactttgc tattactagt ttcctcaatc ttttgtaaat taagaccaat
     1861 ttatttttat tttatatttg tgatcattat aggagctagg aaatactatc gaattctctt
     1921 tcaccaacta atgggattta gtccaggaat agcagtgttt tataaggaga gtcaaacaac
     1981 taagaatctg tttaaatttt actacttctt gtactttaca acactaattt catactattt
     2041 tttctttact tttgtgtatg acaaaccgtt gcttttgcct cttattccat tttctattat
     2101 catagcatta gtacaaaaac tttatagaat tgagaatcaa caattatttc tgttaaaatc
     2161 aaaggtacta acaatactgg aatctaagaa gaattgtgag tttaatcttc aggattatca
     2221 tgaaatttgg aaattgcaat caaaatctga gttgccatgc gtggctttat cttatatcag
     2281 tttgatcaag ccatatcttt cagagagcgt gcgtgaacaa attgatttat tagaagttaa
     2341 gcgatttaaa aaaataaatc atccaatatc actttatggt atgttggatg ttataaaatt
     2401 aaatctatat ttacggcatt ataatgaaaa aaataaatat gaatcaatgt taaagaaaat
     2461 tttagaggta agaccagact ttgttttaat cgagcagaat attgatgata gtttaaatag
     2521 ctcgcaacca ttatctttat ctttagccat ttcagaaatc caacttttgc ttgaagtgta
     2581 tatggggatc aaacatgttt caaccaagtg ataaaaccag aataatattt gccattatag
     2641 gggcaagttg catattagtc agtatgtatc ttattccact tattaaaact gagaataaat
     2701 tttgggaaat acttttattt atattaggtg tattgctaat tggaattgcg ttactaagtc
     2761 aaaaaaaata aattttgaaa tagtattagt gagttcgcaa tcatttattg ctagtggttt
     2821 agaactgtta agtttcaaac aataattgat tttaaacctt aggtaaccta taaaaacaaa
     2881 taaggtagag aaaggatatc ttatctaggt agctaagtga taaaaacaca gtcgtctatc
     2941 acttgttagg aaactatcct aactatgctt aataaaaaag gagaaaataa atggaactcg
     3001 tattaccaaa taattatgtt gttcttgagc aagaagagat gatgtatctt gatgggggat
     3061 tttctattcc gagatggcct gttgcaacag ccattaatat agcttttaat ggtgttttag
     3121 gtggaggagc aatcagtcta gttagaaatt atattcgtaa ttatggtttg cggcgagtta
     3181 caagcgcaat tgctggagca gctgcaagat atgttggggt acgagttgca aatagagtgg
     3241 caggatttgc actgtctgct attaatggat ttgcagcttg gatgtcaatt ggcgatgcta
     3301 ttacaacaat ctgggccaac aatgatgtaa ataggagaga cccaaattta aacgccttgt
     3361 ggtaactaga tatgggtatt aaaatggaaa aaatttttgt tattattttt tttgtatgtc
     3421 tatttatatc atccataact tttttagcct atgattttgt tagcgaagaa ataaaaaagt
     3481 tgattatttg gattaatgtc gtttttttga ttttaatcat agcaatgatg atttatccaa
     3541 aattaagaaa atgataagga cactgtaaaa ttatgatacg taaactaatt gttttcttac
     3601 taatgctccc tctttttgtc ttgtggctag agttgcatgt cctagtgaat aacttactat
     3661 tgaatctaga atctcccctt gattttgtga ttagtatgag tcttgctttc tgtagtttga
     3721 ttttatcaaa aatagtttta gacatactat acgcattgaa agatttatac aagaaagaag
     3781 gtcttattaa gatttttccc tttattttta taagaaggaa aaaagtgaat gtgagattct
     3841 cgccctattt ttcattccat cgtaaaagtt tgtcgcctga tgatttaaga tctaggatta
     3901 tatggagttt tattcttgaa attgctatta tcctagtatt tattttaaaa attccttttg
     3961 caatcatcat gcttactaca atatttttct ggactataat ggatatcaat catctcgttt
     4021 ttaataagac ggaatttctt tttaatcaaa acaaatggca aaaagaagat tcatttgaaa
     4081 gtaatttgca taagatattg atggacaaaa tacaaaaatc agaattaagc tattctgact
     4141 taatgtccct tcttctctat gatgcgatga accaatccac ctttttaacg gatagtgaac
     4201 tttttgagga tattttgaaa aaaatcgaag attctcataa cacccttctg tgtacaggtc
     4261 ttgtcgagtt actgctgtat gagatttcta ttagtaacaa taacaactgg caagaaaagg
     4321 ttgataaaat tagaatacag ctcatcagaa tcaatcaatt agattttttc tattatacaa
     4381 gttggttaag gcaaaatttt gatttctgta tgaatagaga gtatcataaa atgaaatctc
     4441 ggaaattatt actgagtaat aaaaagatag tttaagttcg tcctatttgt aaaacaaatg
     4501 aaacaatttc aactaaggag gagaaaacaa atggaacttg tattaccaaa taattatgtt
     4561 gtgattgatg aagaagtaat gatgtatctt gatgggggag cttatttaag caagcgtgct
     4621 tgtcaaggaa tttgcgcagc agcaggtgta ttggctacag cagcagggaa aatagcttac
     4681 tgtattggat atggtgttct taatagaggt tgtgatatta acgagaaccc ttatccttgg
     4741 gatggattca tatctgcaac agtaagatga gtaatgtaga taagattcga aaaatacaca
     4801 tcatcgtgtg ttgggtgtat atatttttat cattcagggc gattataaat gatacggagt
     4861 attttttgct tattttttta gcttttatct actcaatagt atcactacct ctatattctg
     4921 tgaaaaataa aatagtatct atctgtctag ttataaattc gattctgtta atgagtttcc
     4981 ccattttaat caataagttt ttcccagaaa gttttttgac ttataccgta ttaataagtg
     5041 tttttatcct agagttagca atctttcatt taattaggaa agattttgat attaaattga
     5101 ctaacgaata taagaaaatt agtcagttta gaagcaaggt gtctcaatct ccttggataa
     5161 aatatttaga gatttctagt tttatattaa ctatatttcc atctattctt tatggtaaag
     5221 ttgataatca tgtactgact cttatctttt tgataaaaat ttgtgtagat actacgataa
     5281 aatttttatt catcagatta tttgacacaa gtactttaat gaagaggaga atattttttc
     5341 ttttcgcatt ggatgttata gcttacttat ttttaggata tcttttagtg attcaaaaag
     5401 caggctattt gttttcggtt ttacttcttt tttctaattt ttcagttcca tttatcaaag
     5461 aaaaggaata cgaattattt aaaaatagca agtaatagaa atatggatta aatcttagaa
     5521 cggcttaaaa tcagatatga taaagggaaa tagtcttatc taggtaacta agtgctacaa
     5581 acacaatcga ggatcacttg ttaggattac attttaatca tgcttaataa gaatggagaa
     5641 ttcctatggg gattgtatta ctctgaagtt tcgaatacct tagttctcgt gattttgagc
     5701 tattctagct ttagaatcct tcagaacgta aaattttaag cagtcaaaga cttagaatag
     5761 cctgaaaaca tttattttat agcaattcta ggcttagaat tgctcatata tatgtatttg
     5821 agctgctcga tagttaggac agctctattc tgagaaatct gagctatcaa tgcttcagaa
     5881 tagtatttcg ccaatggttt ttattgaaga ggtgattgtg ttatgatagt ctaaaataaa
     5941 attgatttaa tagagtaaat ggagaatcgt tacatgaaac atttttttgc aggaattggt
     6001 gagataaaac ttgttggcta cttattgtat atatgtgtag gactagcccc tctttttcat
     6061 atatatgtca taggttcgga actgagtttt gtgaaaatag tgttatctat tttgggagtt
     6121 atatttgtaa gtatgttaac tattgctcga atttatcgga cttttctata aagaatagtt
     6181 tggacttaaa ctgtatctaa aaacagaggt tggtcgatta tcagcctctt tcttgtcgtt
     6241 gaaaagagtg agatatattg acttttgaaa aaaagatgtc ataattgagt tgggataaac
     6301 ctaaaagtaa tatagtagat tgaatctgga atagtccgtt atgactgtta aaatatttct
     6361 agaaattaat ttgactttcc taatcgattt gttcacatct tgtttcaatc tactatactt
     6421 tctcgttaaa ccgttcggca attcatggtg acatggacac atagtagtaa gcacactatg
     6481 tggcttggca gagctaaaaa ctgttccctt gcgataagcc taataagcac aacataggga
     6541 gttagagaag ccgactctaa tcaaccactt tgggcaatag tgagaactgc cccgtgcttt
     6601 tttattttga gaaaatatgg agtttgtcgt tgaaattact tgattgtatt ttggactatc
     6661 aagaaagatt caatggaaaa acatgtcaag tatcaacgaa ttataagtat ttagagattt
     6721 tcaaagtgaa tttttgtttg actgatttac atcatttatt tgacttatac aaaatcacac
     6781 gagattatgc tagtcaaaca aaacctgcta ttcaagatgg tgtttttatt ttagaagatt
     6841 ttagaaatat cctatgtaca atgatgtaat cgaaaggata tctttatgtg agtttatcgg
     6901 cgatatcttc tatatctaag ctagcaagtt gttgcatcgt agctaaggat ttatctaaaa
     6961 atactatgaa attggacgtc atattttttg aggataaaaa taaaagatcc gcagttttag
     7021 gtttacgaag agacaaaagc ggagtattta aaccagttac tctacatttt acaagcgcta
     7081 agaaatatgc taaagttcgt aaaacagatg tgaaagaaat gaaatggcta taaagattgt
     7141 ccgcaggctt aagcttgcgt tttttgttgt ttaacgaaat taaaaaacaa gctctctcat
     7201 cggaaatgtt tttataggaa tgaaggaaga tgatgctatg tttaaaaaga gaatcgaaaa
     7261 gggcaaaagt agtgtcttta tctttttgga gtagaagctt atgatataga aatttgtaat
     7321 aaaaatgtaa tataaaacat ttgacaaata tttacggggg gagtatactt aatataagta
     7381 tagtctaaaa atgactatca gaaaagaggt aaatttagat gaataagaaa aaaatgattt
     7441 taacaagtct agccagcgtc gctatcttag gggctggttt tgttacgtct caacctactt
     7501 ttgtaagagc agaagaagct cccgtagcta gtcagtctaa agctgagaaa gactatgatg
     7561 cagcagtgaa aaaatatgaa gctgctaaga aggaatatga ggacggaaaa gctgctcaga
     7621 aaaagtatga agatgatcag aagaaaactg aggagaaagc ggaagaagaa agaaaagctt
     7681 ctgaagaaga acaagctgca aatctgaaat atcaacaaga gttggttaaa tatatacgtg
     7741 aaaatgatcc aacaaaaaaa gctgaagcta agaaagcaat ggatgaggct gagaaagagt
     7801 ataagaaaaa acaaacggaa tttgctgaag ttcgtgcaaa ggtaattcct agcgcggaag
     7861 aattaaaaaa gactagacaa aaagcagaag aggctaaagc aaaagaagca gaacttacta
     7921 aaaaagtaga agaagctgag aaaaaagtta ctgaagccaa acaaaaagtg gatgcagaac
     7981 atgctgaaga agtcgctcct caagctaaaa tcgctgaatt ggaacatgaa gttcagaaac
     8041 tagaaaaagc tctcaaagag attgatgagt ctgattcaga agattatgtt aaagaaggtc
     8101 tccgtgctcc tcttcaattt gaattggatg ttaagcaagc taaactatca aaacttgaag
     8161 agttgagtga taagattgat gagttagacg ctgaaattgc aaaacttgaa aaagatgtag
     8221 aagatttcaa aaactcagac ggtgagcaag ctggacaata ccttgctgca gctgaagaag
     8281 acttagttgc taaaaaagct gaattagaaa aaactgaagc tgaccttaag aaagcagtta
     8341 atgagccaga aaaaccagct gaagaaactc cagctccagc accaaaacca gagcaaccag
     8401 ctgaacaacc aaaaccagcg ccggctcctc aaccagaaaa accagctgaa gagcctgaga
     8461 atccagctcc agcaccacaa ccagagaagt cagcagatca acaagctgaa gaagactatg
     8521 ctcgtagatc agaagaagaa tataatcgct tgacccaaca gcaaccgcca aaagcagaaa
     8581 aaccagctcc tgcaccacaa ccaggttgga aacaagaaaa cggtatgtgg tacttctaca
     8641 atactgatgg ttcaatggct acaggttggc tacaaaacaa cggttcatgg tactacctca
     8701 acgctaatgg tgctatggct acaggttggc tccaatacaa cggttcatgg tactacctca
     8761 acgctaatgg tgctatggct acaggttggc tccaatacaa cgattcatgg tattacctaa
     8821 acgctaacgg
//
LOCUS       DAVBBO010000073         8550 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ST1
            SAMEA2066453-rid20184263.denovo.073, whole genome shotgun sequence.
ACCESSION   DAVBBO010000073 DAVBBO010000000
VERSION     DAVBBO010000073.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2066453
            Sequence Read Archive: ERR351777
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 8550)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8550)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980402.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980402.1
            Genome Coverage       :: 176x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:17:33
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,141
            CDSs (total)                      :: 2,104
            Genes (coding)                    :: 1,953
            CDSs (with protein)               :: 1,953
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 16S)
            partial rRNAs                     :: 1 (23S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 151
            CDSs (without protein)            :: 151
            Pseudo Genes (ambiguous residues) :: 0 of 151
            Pseudo Genes (frameshifted)       :: 73 of 151
            Pseudo Genes (incomplete)         :: 76 of 151
            Pseudo Genes (internal stop)      :: 40 of 151
            Pseudo Genes (multiple problems)  :: 32 of 151
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8550
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2066453-rid20184263.denovo.073"
                     /strain="ST1"
                     /db_xref="taxon:1313"
     gene            <1..128
                     /locus_tag="VQU30_001969"
     CDS             <1..128
                     /locus_tag="VQU30_001969"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611513.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="IS3 family transposase"
                     /protein_id="HET2448013.1"
                     /translation="FQSLNQLEQAIVDYIDYYNNKRIKVKLKGLSPVQYRTKSFG"
     gene            complement(257..460)
                     /locus_tag="VQU30_001970"
     CDS             complement(257..460)
                     /locus_tag="VQU30_001970"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000594204.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HET2448014.1"
                     /translation="MIKLYSPYAFLSKYLGAILLSFFCYYAKEIGCNNLTLSVWNDNE
                     GALRFYQRQGMKPQETTMEMIID"
     gene            complement(453..1535)
                     /locus_tag="VQU30_001971"
     CDS             complement(453..1535)
                     /locus_tag="VQU30_001971"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000040939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase P family protein"
                     /protein_id="HET2448015.1"
                     /translation="MSKLQQILTYLESEKLDVAVVSDPVTINYLTGFYSDPHERQMFL
                     FVLADQEPLLFVPALEVERASSTVSFPVVGYVDSENPWQKIKHALPQLDFKRVAVEFD
                     NLILTKYHGLKTVFETAEFDNLTPRIQRMRLIKSADEVQKMMVAGLYADKAVHVGFDN
                     ISLDKTETDIIAQIDFAMKREGYEMSFDTMVLTGDNAANPHGIPAANKVENDALLLFD
                     LGVLVNGYASDMTRTVAVGKPDQFKKDIYNLTLEAQQAALDFIKPGVTAHEVDRAARE
                     VIEKAGYGEYFNHRLGHGIGMDVHEFPSIMEGNDMVIEEGMCFSVEPGIYIPGKVGVR
                     IEDCGVVTKDGFDLFTSTSKDLLYFD"
     gene            complement(1661..2443)
                     /locus_tag="VQU30_001972"
     CDS             complement(1661..2443)
                     /locus_tag="VQU30_001972"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 1 glutamine amidotransferase"
                     /protein_id="HET2448016.1"
                     /translation="MVYTSLSSKDSNYPYQLNIAHLYGNLMNTYGDNGNILMLKYVAE
                     KLGAHVTVDIVSLHDDFDENHYDIAFFGGGQDFEQSIIADDLPAKKESIDNYIQNDGV
                     VLAICGGFQLLGQYYVEASGKRIEGLGVMGHYTLNQTNNRFIGDIKIHNEDFDETYYG
                     FENHQGRTFLSDDQKPLGQVVYGNGNNEEKVGEGVHYKNVFGSYFHGPILSRNANLAY
                     RLVTTALKKKYGQDIQLPAYEDILSQEIAEEYSDVKSKADFS"
     gene            complement(2443..3786)
                     /locus_tag="VQU30_001973"
     CDS             complement(2443..3786)
                     /locus_tag="VQU30_001973"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011836724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Mur ligase family protein"
                     /protein_id="HET2448017.1"
                     /translation="MNLKTTLGLLAGRSSHFVLSRLGRGSTLPGKVALQFDKDILQSL
                     AKNYEIVVVTGTNGKTLTTALTVGILKEVYGQVLTNPSGANMITGIATTFLTAKSSKT
                     GKNIAVLEIDEASLSRICDYIQPSLFVITNIFRDQMDRFGEIYTTYNMILDAIRKVPT
                     ATVLLNGDSPLFYKPTIPNPIEYFGFDLEKGPAQLAHYNTEGILCPDCQGILKYEHNT
                     YANLGAYICEGCGCKRPDLDYRLTKLVELTNNRSRFVIDGQEYGIQIGGLYNIYNALA
                     AVAIARFLGADSQLIKQGFDKSRAVFGRQETFHIGDKECTLVLIKNPVGATQAIEMIK
                     LAPYPFSLSVLLNANYADGIDTSWIWDADFEQITDMDIPEINAGGVRHSEIARRLRVT
                     GYPAEKITETSNLEQVLKTIENQDCKHAYILATYTAMLEFRELLASRQIVRKEMN"
     gene            complement(3885..5201)
                     /locus_tag="VQU30_001974"
     CDS             complement(3885..5201)
                     /locus_tag="VQU30_001974"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000958936.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-containing oxidoreductase"
                     /protein_id="HET2448018.1"
                     /translation="MLTYDLIVIGFGKAGKTLAGKLASAGKKVALVERSKAMYGGTCI
                     NIGCIPTKTLLVAAEKDLSFEEVIATKNTITGRLNGKNYATVAGTGVDIFDAEAHFLS
                     NKVIEIQAGDEKKELTAETIVINTGAVSNVLPIPGLATSKNIFDSTGIQSLDKLPEKL
                     GILGGGNIGLEFAGLYNKLGSKVTVLDALDTFLPRAEPSIAALAKQYMEEDGIELLQN
                     IHTTEIKNDGDQVLVVTEDETYRFDALLYATGRKPNVEPLQLENTDIELTERGAIKVD
                     KHCQTNVPGVFAVGDVNGGLQFTYISLDDFRVVYSYLAGDGSYTLEDRLNVPNTMFIT
                     PALSQVGLTESQAADLKLPYAVKEIPVAAMPRGHVNGDLRGAFKAVVNTETKEILGAS
                     IFSEGSQEIINIITVAMDNKIPYTYFTKQIFTHPTLAENLNDLFAI"
     gene            5394..6615
                     /locus_tag="VQU30_001975"
                     /pseudo
     CDS             5394..6615
                     /locus_tag="VQU30_001975"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000841575.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="OFA family MFS transporter"
     gene            6814..8388
                     /locus_tag="VQU30_001976"
     CDS             6814..8388
                     /locus_tag="VQU30_001976"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000671067.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HET2448019.1"
                     /translation="MKFNELNLSADLLAEIEKAGFVEASPIQEQTIPLALEGKDVIGQ
                     AQTGTGKTAAFGLPTLEKIRTEEATIQALVIAPTRELAVQSQEELFRFGRSKGVKVRS
                     VYGGSSIEKQIKALKSGAHIVVGTPGRLLDLIKRKALKLQDIETLILDEADEMLNMGF
                     LEDIEAIISRVPENRQTLLFSATMPDAIKRIGVQFMKAPEHVKIAAKELTTELVDQYY
                     IRVKEQEKFDTMTRLMDVAQPELAIVFGRTKRRVDELTRGLKIRGFRAEGIHGDLDQN
                     KRLRVLRDFKNGNLDVLVATDVAARGLDISGVTHVYNYDIPQDPESYVHRIGRTGRAG
                     KSGQSITFVAPNEMGYLQIIENLTKKRMKGLKPASVEESFQSKKQVALKKIERDFADE
                     TIRANFEKFGKDARKLAAEFTPEELAMYILSLTVQDPDSLPEVEIAREKPLPFKPSGN
                     GFGGKAKGGRGGRRGDDRRERDRRGNGRRDEFKKGSRGNDRFDKEKRYRKDNKKPRNT
                     LSEKQTGFVIRNKGDK"
BASE COUNT         2454 a         1652 c         1892 g         2552 t
ORIGIN      
        1 cgtttcagtc gcttaatcaa ttggaacaag ctattgtaga ctatattgat tactacaaca
       61 ataaacgaat taaggtaaaa ctaaaaggac ttagtcctgt gcaatacaga actaaatcct
      121 tcggataaat taattgtcta actgtttggg ggcagtacat attcaacacc tgatactatg
      181 cgttttattg tgggaagatt ttcctcattt tctagtgaaa ttgaactttt tctaacatct
      241 tttgatagat gacttcttaa tcaattatca tttccattgt tgtttcttgg ggtttcatcc
      301 cttgtctttg ataaaagcgg agagcaccct cgttatcatt ccagacactt agggttagat
      361 tattgcagcc aatttcttta gcataatagc agaaaaatga caataaaata gcccctagat
      421 attttgaaag gaaagcatag gggctatata gtttaatcaa aataaagcaa atctttgctg
      481 gtgcttgtaa agaggtcgaa gccatccttg gtaacaacac cgcagtcttc aatacgaaca
      541 ccgactttac cagggatata gatacctggt tcaacagaga agcacatgcc ttcttcgatg
      601 accatgtcgt ttccttccat gatagatggg aattcatgga catccatacc gataccatgc
      661 ccgagacggt ggttgaagta ctcaccataa ccagcttttt cgatgacctc acgggcagcg
      721 cggtccactt catgagcagt cacacctggc ttgataaagt caagagcagc ttgttgggct
      781 tcaagagtca agttgtaaat atctttcttg aattggtctg gtttgccgac agcgactgta
      841 cgagtcatat ctgacgcata gccattgacc agaacaccca ggtcaaagag gagaagagca
      901 tcattttcaa ccttattagc tgctggaatg ccgtgtggat tcgcagcatt atcaccagtc
      961 aagaccatgg tatcaaagct catttcataa ccttcacgtt tcatggcaaa gtcgatttgt
     1021 gcgatgatat ctgtctcagt cttatcaaga gaaatattgt caaaaccaac atgaacagcc
     1081 ttgtcagcat aaagacctgc aaccatcatt ttttgcactt catcagctga tttgatgagg
     1141 cgcatgcgtt ggatacgagg agtgaggttg tcaaactcag cagtctcaaa aactgttttc
     1201 aaaccatggt atttggtcaa gatgagattg tcaaactcaa cagcgacacg tttgaagtca
     1261 agttgtggaa gagcatgttt gattttttgc catggatttt cagaatcgac atagcccact
     1321 actgggaagg aaacggtgct acttgcacgt tctacttcaa gagctgggac aaagaggaga
     1381 ggttcctgat ccgctaggac aaagaggaac atttggcgtt catggggatc actgtaaaaa
     1441 ccagtgaggt aattgattgt gacggggtca gatacgacag cgacgtctag tttttctgat
     1501 tcaagatatg ttaggatttg ttgtaattta gacatatgct accttctttc tacccctcta
     1561 ttttggcaaa aaatgagaga aaatgcaagg gagaagggta aaagaaaaga caaaaaactc
     1621 cgacaagata acggagttct ttgatatcat tttcctttgt ttaagaaaag tcagccttgc
     1681 ttttgacgtc actgtactct tcagcgattt cttggctgag aatgtcctca taggcaggga
     1741 gttggatgtc ctgaccatat ttcttcttga gggcagtagt aactaggcga taagccagat
     1801 tggcattacg agagaggata ggcccgtgga agtaggaacc aaagacattc ttataatgaa
     1861 ccccttcacc gaccttttct tcgttgtttc catttccata gacaacctgt cccagcggtt
     1921 tttggtcatc agagaggaag gtacgacctt ggtgattttc aaatccatag taggtttcat
     1981 cgaaatcttc attgtgaatc ttgatgtcac cgataaaacg gttattggtc tggttgagcg
     2041 tgtagtgtcc catgacccct agcccttcga tacgttttcc tgaagcttca acataatatt
     2101 gacccaatag ttggaaacca ccgcagatag ccagaactac accgtcgttt tggatgtagt
     2161 tgtcaatgct ctctttttta gcaggtaggt cgtctgcaat gatactttgt tcaaagtctt
     2221 gaccaccacc gaaaaaggcg atgtcgtagt gattttcatc aaagtcatca tggagagaaa
     2281 cgatgtcaac ggtcacatgg gctcccagtt tttcagccac atacttgagc atgaggatgt
     2341 ttccattgtc cccgtaggta ttcatgagat ttccgtagag gtgggcaatg ttgagctgat
     2401 aggggtaatt gctatctttt gaggaaagtg aagtataaac cattagttca tctcctttct
     2461 aacaatctga cgactagcca gcagttcacg aaattccagc atggcagtat aagttgccag
     2521 aatataggca tgcttgcagt cttgattctc aatggtcttg agaacttgct ccagattact
     2581 cgtttcagtg attttctcag ctggatagcc agtcactcgg aggcgacgag cgatttcaga
     2641 atgacgaaca ccgccagcgt tgatttcagg aatgtccatg tcagtgattt gctcaaagtc
     2701 tgcatcccag atccagctag tgtcaattcc atctgcatag ttggcattaa ggaggacaga
     2761 taggctaaat ggataaggtg ctagtttgat catttcgata gcttgggttg caccgactgg
     2821 atttttaatc aagacaaggg tacattcctt gtcaccgata tgaaaggttt cttggcgtcc
     2881 aaagacagca cggctcttgt caaatccctg tttgatgagt tgggaatctg cgccgaggaa
     2941 acgggcgatg gccacagcag ctagggcgtt atagatatta tagagcccgc cgatttggat
     3001 accgtattct tggccgtcta tgacaaagcg agagcgattg ttggtcaact caaccagttt
     3061 tgtcaaacga tagtcgagat caggacgttt acatccacaa ccttcacaga tataggcacc
     3121 caagtttgca taggtattat gctcatattt gaggatgcct tggcagtcag gacagagaat
     3181 cccttcggta ttgtagtgag ccagttgggc tggtcctttt tccaagtcaa aaccaaaata
     3241 ctctataggg tttggaatag ttggcttgta gaaaagtgga ctgtctccgt taaggagaac
     3301 agtagcagtt ggaacttttc gaatggcatc caatatcatg ttataggtag tatagatttc
     3361 accgaaacgg tccatctggt cacggaagat attagtaatg acaaaaagac taggctggat
     3421 atagtcacag atacgagata gactggcttc gtcaatttcg aggacggcaa tatttttccc
     3481 agtttttgaa gatttggctg ttaggaaggt tgttgcaatc cctgtaatca tgttggcacc
     3541 gcttgggttg gttagaactt gaccataaac ctcttttaaa atgccgacag tgagggcagt
     3601 tgtcagggtt tttccatttg ttccagtgac aacgacaatc tcgtagttct tagctaggct
     3661 ttgtaaaata tctttatcaa attgaagggc gactttccct gggagcgtac ttccacgtcc
     3721 aagacggctt aaaacgaagt gggaagaacg cccagcaaga aggcccaaag tagtttttaa
     3781 gttcatgttt ctattatatc acaaaagagg gaaaagacag atttggtgtt tcgtagaagt
     3841 aaaaacagcc caaagagggc tgtcagttaa gatgagattt caacttaaat cgcaaacaag
     3901 tcattcaagt tctcagccaa ggttgggtga gtgaagattt gttttgtgaa gtaagtgtaa
     3961 ggaatcttgt tgtccatagc aacagtaatg atgttgatga tttcttgaga accttctgag
     4021 aagatgcttg caccaagaat ttcttttgtt tcagtattaa caacagcttt gaaagctccg
     4081 cgaaggtctc catttacgtg accacgaggc atggctgcaa cagggatttc tttcactgcg
     4141 tatggaagtt tcaaatcagc tgcttggctt tcagtcaaac caacttgtga aagtgcaggt
     4201 gtgatgaaca tagtatttgg cacattgaga cggtcctcaa gtgtgtagct gccatctcca
     4261 gcaaggtagc tgtaaacaac acggaagtca tcaagtgaaa tgtaagtaaa ttgaaggcca
     4321 ccgttgacat ctccaactgc aaagacacca ggaacgtttg tttgacagtg tttgtctact
     4381 ttaatagcac cacgttcagt tagttcaata tctgtatttt caagttgaag tggttctaca
     4441 tttggtttgc gtccagttgc gtagagaagg gcgtcgaaac ggtaagtttc gtcttcagtt
     4501 acgacaagca cttggtcacc atcgtttttg atttcagtag tatggatatt ttgaagcaat
     4561 tcaatgccat cttcttccat gtattgttta gcaagagctg cgatggaagg ttctgcacga
     4621 ggtaggaatg tatccaaggc atctaggact gtgaccttgc ttccaagttt gttgtaaagg
     4681 ccggcaaatt caagaccgat atttccgcca ccaaggattc caagtttttc aggtaatttg
     4741 tccaagcttt ggatacctgt tgagtcaaag atgtttttgc ttgtagcaag tccaggaatt
     4801 ggcaagacgt ttgaaacagc accagtgttg atgacgattg tttcagcagt cagttctttc
     4861 ttttcatcac cagcttggat ttcgatgact ttatttgaaa ggaagtgagc ttccgcatca
     4921 aagatatcta cgcctgtacc agcaacagtc gcatagtttt taccgttgag gcgaccagtg
     4981 atcgtgtttt tagtagcaat cacttcttca aaagacaagt ccttttcagc agcaactagc
     5041 aaggttttag ttgggataca accaatgttg atacaagttc caccgtacat agccttgctg
     5101 cgttcaacga gggcaacttt tttgccagct gaagccaatt tacctgctag tgttttacca
     5161 gctttaccaa atccaataac aattaaatcg tatgttaaca tttatcttcc tcctattcga
     5221 atttcattct agcacaagaa aaaaactttt gcacaattct gctacggaaa agacagaaaa
     5281 agataaaaac gctttccaga caaaaaacta gtaatttttt gacaagcttg ataaactaaa
     5341 atcctatcta tttttatata agaaagaata aatgttcgaa aataggaggt tttatgaaat
     5401 cgaatcgtta tattattgcc tttgctgggg tcattttaca cttaatgctg ggttcgactt
     5461 atgcttggag tgtttatcgt aaccctatta ttgaaaaaac gggatgggat caggcttctg
     5521 ttgccttcgc ctttagtcta gcaatctttt gtttgggctt atcggctgca tttatggggc
     5581 gtttggtaga aaaatttggt ccgaaagtca tggggagtct atctgctttt ctatacgcag
     5641 gtggaaatat cttaacagga tttgcaatag accgtcagga actgtggttg ttgtatctag
     5701 cttatggcat tttaggtggg cttggtttgg gagcaggcta tattacccct gtgtcaacga
     5761 ttataaaatg gtttcctgat aaacgtggtc tcgcaacagg tttagcgatt atggggtttg
     5821 gttttgcttc tttattgact agtcccatag cgcaacacct catcgcaggg gtagggattg
     5881 tagaaacttt ttatatttta ggagcaagtt actttattat catgctccta gcttcacaat
     5941 tcattaagcg tccaaatgag caagagcttg caattttatc ttcttcaggg aaagaaaaaa
     6001 cagcctcttt gacgcaagga atggctgcaa atcaggctct aaaaagcaat cggttttata
     6061 tgctttggat tattttcttt atcaacatag cttgtggttt aggcttaatt tcagcggcat
     6121 cgccaatggc acaggagatg gctggcttgt ctacaagtca tgcagcagta atggtgggtg
     6181 ttttggggat tttcaatgga tttggtcgct tgctctgggc gagtttgtct gactatatcg
     6241 gtcgccctct aacctttagt atattactgc ttgtcaatct tttctctctc actttggctc
     6301 tttacagatt ccgttttatt tgtagttgct atgtctattt tgatgacttg ctatggagct
     6361 ggtttttctt tgattccagc ttatctcagt gatatttttg gaaccaagga attggccgct
     6421 ctgcatggtt atattttaac agcttgggca atggctggtt tagcgggacc tattttatta
     6481 gcagagactt ataaaatggc tcattcgtac acacaaacct tgttcgtttt tctcatttta
     6541 tacagtatcg ccttggcttt gtcttattat ctaggtcgtt caatcaaaaa agaaagtcaa
     6601 aaaccgctta catgattttc tgtagaaatg gggctatctt ttgctctggt cttgtgttat
     6661 actagatagg ttgcaaagaa aacagtactt ttcttttgtg gaaaagaagc aacacgattt
     6721 tatatctagt tatatgaaaa tacgtcataa aaagaaaagt ataaactaag ccctataggg
     6781 tggcttcgca ccacctttag aaagaagaat aacgtgaaat ttaatgaatt aaacttgtct
     6841 gctgatttgc tagcagaaat tgaaaaagct ggttttgtag aagctagtcc tatccaagaa
     6901 caaactattc ctttggccct tgaaggcaag gatgttatcg gtcaagctca gactggtaca
     6961 ggaaaaactg cagcctttgg cttgcctacc cttgaaaaaa tccgtacaga agaagcgact
     7021 atccaagctt tggtcatcgc tccaactcgt gaactagctg tccaaagtca agaagaactc
     7081 ttccgctttg gtcgtagtaa gggagtcaaa gtccgttcag tatatggcgg atcaagcatt
     7141 gaaaaacaaa ttaaggctct taaatctggt gcccatatcg tggtgggaac tccaggtcgc
     7201 ctcttggact tgattaaacg caaggccttg aaattacaag acattgaaac ccttatcctt
     7261 gacgaagcgg atgaaatgct taacatgggc ttccttgaag acatcgaagc cattatttcc
     7321 cgtgtacctg agaaccgtca aactttgctt ttctcagcaa ctatgccaga tgccatcaaa
     7381 cgtatcggtg ttcagtttat gaaagcccct gaacatgtca agattgcggc taaggaattg
     7441 acaacagaat tggttgacca gtactatatc cgtgttaagg aacaagaaaa atttgacacc
     7501 atgactcgtc tcatggatgt ggcacaacca gaactcgcta ttgtatttgg tcgtaccaaa
     7561 cgccgtgtgg atgaattgac tcgtggtttg aaaattcgtg gcttccgtgc agaaggaatt
     7621 catggcgacc tagaccaaaa caaacgtctt cgtgtccttc gtgactttaa aaatggcaat
     7681 cttgatgttt tggttgcgac agacgttgca gcgcgtggtt tggatatttc aggtgtgacc
     7741 catgtctaca actacgatat tccacaagat cctgagagtt atgttcaccg tatcggtcgt
     7801 acaggtcgtg ctggtaagtc aggtcaatct attacttttg ttgctccaaa cgaaatgggt
     7861 taccttcaaa tcattgaaaa cttgactaag aaacgcatga aaggtctcaa acctgcaagt
     7921 gtagaagaat ccttccaatc aaaaaaacag gtagctctca agaaaatcga acgtgatttt
     7981 gcagatgaaa ccattcgtgc caactttgag aaatttggta aggatgctcg caaattggct
     8041 gctgagttta ctccagaaga attggcaatg tatatcttga gtctgacagt ccaagaccca
     8101 gatagccttc cagaagtgga gattgcacgt gaaaaaccac taccgtttaa accatcaggt
     8161 aatggtttcg gtggtaaagc taagggaggt cgtggaggcc gtcgtgggga cgaccgtcga
     8221 gagcgtgatc gccgtggcaa tggtcgccgt gatgagttca aaaaaggaag tcgtggcaac
     8281 gatcgttttg ataaggaaaa acgttaccgt aaggataata aaaaaccacg caatacttta
     8341 agcgaaaagc aaacaggctt tgttattcgt aacaaaggcg ataaataaga aaaagcggtt
     8401 caaaatgaat cgctttttta tataaggaga ccgaatgtga aaagacaaat aaaattacta
     8461 tattatcttt tataatgtta tgatacacaa aaataggcaa cttgtcaata gaaaaggaac
     8521 aatttaatta aaaatattct ggtttttaat
//
LOCUS       DAVBBO010000074         8481 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ST1
            SAMEA2066453-rid20184263.denovo.074, whole genome shotgun sequence.
ACCESSION   DAVBBO010000074 DAVBBO010000000
VERSION     DAVBBO010000074.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2066453
            Sequence Read Archive: ERR351777
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 8481)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8481)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980402.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980402.1
            Genome Coverage       :: 176x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:17:33
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,141
            CDSs (total)                      :: 2,104
            Genes (coding)                    :: 1,953
            CDSs (with protein)               :: 1,953
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 16S)
            partial rRNAs                     :: 1 (23S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 151
            CDSs (without protein)            :: 151
            Pseudo Genes (ambiguous residues) :: 0 of 151
            Pseudo Genes (frameshifted)       :: 73 of 151
            Pseudo Genes (incomplete)         :: 76 of 151
            Pseudo Genes (internal stop)      :: 40 of 151
            Pseudo Genes (multiple problems)  :: 32 of 151
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8481
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2066453-rid20184263.denovo.074"
                     /strain="ST1"
                     /db_xref="taxon:1313"
     gene            <1..1038
                     /locus_tag="VQU30_001977"
     CDS             <1..1038
                     /locus_tag="VQU30_001977"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001018351.1"
                     /note="Produces ATP from ADP in the presence of a proton
                     gradient across the membrane. Subunit I is part of the
                     membrane proton channel; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit I"
                     /protein_id="HET2448020.1"
                     /translation="IKVMDERFGHSIYIYESETLSDNQDEIPIKLTNHSLIEPFELLT
                     EMYALPKYYEKDPTPVLAPFYFTFFGMMVADLGYGLLLFLGTMLALKIFHLPSETKRF
                     LKFFNILGVAVAIWGGIYGSFFGYELPFHLISTTSDVMIILVVSVVFGFITVFAGLLA
                     SGLQKVRMKKYAEAYNSGFVWCVILLGLLFIAVGMLMPDMRLLFVLGKWVSIFNAVGI
                     LVVSIIQAKSLSGIGAGLFNLYNISSYIGDLVSFTRLMALGLSGASIASAFNLIVGLF
                     PGTLAKLTIGLVLFILLHAINIFLSLLSGYVHGARLIFVEFFGKFYEGGGKPFQPLKA
                     SEKYIKVITKN"
     gene            1054..1530
                     /locus_tag="VQU30_001978"
     CDS             1054..1530
                     /locus_tag="VQU30_001978"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000400486.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit K"
                     /protein_id="HET2448021.1"
                     /translation="MEHLATYFSTYGGAFFAALGIVLAVGLSGMGSAYGVGKAGQSAA
                     ALLKEQPEKFASALILQLLPGTQGLYGFVIGILIWLQLTPELPLEKGVAYFFVALPIA
                     IVGYFSAKHQGNVAVAGMQILAKRPKEFMKGAILAAMVETYAILAFVVSFILTLRV"
     gene            1564..2145
                     /locus_tag="VQU30_001979"
     CDS             1564..2145
                     /locus_tag="VQU30_001979"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000067169.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2448022.1"
                     /translation="MSNLENLRESVIEQAHEKGRMKLLDSKKKIDDEFEMQKSVIVKK
                     KEVEHERKLKELQQKYQIIFQQLKNKERQSTLVSKQKILKELFQSALIEMESWSADKE
                     MEFIYRILERYSQQEVIVTFGERTLAKFNLEQLEKLKFSFPNHLFSEQPISNESGLLI
                     SIGKIDDNYLYKTLIGSISKEESSSIANQIFIN"
     gene            2210..3217
                     /locus_tag="VQU30_001980"
     CDS             2210..3217
                     /locus_tag="VQU30_001980"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000380539.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATPase subunit"
                     /protein_id="HET2448023.1"
                     /translation="MDTNLFSKINTTISVKENDFITEDKFQKIIQSKDTETMAFILEA
                     TPYHLSIDVLENPSQTETSLMTKLVNDYRWAYAESPSNKIVTLFALRYVYHNIKVLLK
                     SKAAIKKDFSKLLIPIGIFDIESLKHLVSSLHSDTLPDFMVHEVESIWNEYETFNNIR
                     VLDVGADLAYFKHLKLLSNELDEVLSQVIVAMIDFYNIITVKRGLSQNKSHGDILQLL
                     SDEGSISAKEFIYIVENQEIFVWFNKINPSLDSIFSTYELKMQDATISSSELEFLCDL
                     LLYKILDQGRYNVDGPLVLARYLLGCEFEVKNLRMIISALQNTIPFGSIKERIRPHYG
                     S"
     gene            3207..3527
                     /locus_tag="VQU30_001981"
     CDS             3207..3527
                     /locus_tag="VQU30_001981"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000387939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit F"
                     /protein_id="HET2448024.1"
                     /translation="MEANKYKIGIIGSRDIILPFSMIGFDIFPAYQEQEAINTLRKLA
                     QSDYGVIYITEDIASMILDTIRHYDSQVVPAIILLPTHKQGLNLGLKRIEDNVEKAVG
                     HNIL"
     gene            3590..5365
                     /locus_tag="VQU30_001982"
     CDS             3590..5365
                     /locus_tag="VQU30_001982"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit A"
                     /protein_id="HET2448025.1"
                     /translation="MTQGKIIKVSGPLVIASGMQEANIQDICRVGKLGLIGEIIEMRR
                     DQASIQVYEETSGLGPGEPVVTTGEPLSVELGPGLISQMFDGIQRPLDRFKLATHNDF
                     LVRGVEVPSLDRDIKWHFDSTIAIGQKVSTGDILGTVKETEVVNHKIMVPYGVSGEVV
                     SIASGDFTIDEVVYEIKKLDGSFYKGTLMQKWPVRKARPVSKRLIPEEPLITGQRVID
                     TFFPVTKGGAAAVPGPFGAGKTVVQHQVAKFSNVDIVIYVGCGERGNEMTDVLNEFPE
                     LIDPNTGQSIMQRTVLIANTSNMPVAAREASIYTGITMAEYFRDMGYSVAIMADSTSR
                     WAEALREMSGRLEEMPGDEGYPAYLGSRIAEYYERAGRSQVLGIPEREGTITAIGAVS
                     PPGGDISEPVTQNTLRIVKVFWGLDAPLAQRRHFPAINWLTSYSLYKDSVGIYIDGKE
                     KTDWNSKITRAMNYLQRESSLEEIVRLVGIDSLSDNERLTMEIAKQIREDYLQQNAFD
                     SVDTFTSFAKQEAMLSNILTFADQANHALELGSYFTEIMEGTVAVRDRMARSKYVSED
                     RLDEIKIISNEITHQIHLILETGGL"
     gene            5366..6751
                     /locus_tag="VQU30_001983"
     CDS             5366..6751
                     /locus_tag="VQU30_001983"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000111247.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit B"
                     /protein_id="HET2448026.1"
                     /translation="MSVIKEYRTASEVVGPLMIVEQVNNVSYNELVEIQLHNGEIRRG
                     QVLEIHEDKAMVQLFEGSSGINLEKSKIRFAGHALELAVSEDMVGRIFNGMGKPIDGG
                     PDLIPEKYLDIDGQAINPVSRDYPDEFIQTGISSIDHLNTLVRGQKLPVFSGSGLPHN
                     ELAAQIARQATVLNSDENFAVVFAAMGITFEEAEFFMEELRKTGAIDRSVLFMNLAND
                     PAIERIATPRIALTAAEYLAFEKDMHVLVIMTDMTNYCEALREVSAARREVPGRRGYP
                     GYLYTNLSTLYERAGRLVGKKGSVTQIPILTMPEDDITHPIPDLTGYITEGQIILSHE
                     LYNQGYRPPINVLSSLSRLKDKGSGEGKTRGDHAPTMNQLFAAYAQGKKVEELAVVLG
                     ESALSDVDKLYVRFTKRFEEEYINQGFYKNRNIEDTLNLGWELLSILPRTELKRIKDD
                     LLDKYLPLVEV"
     gene            6774..7385
                     /locus_tag="VQU30_001984"
     CDS             6774..7385
                     /locus_tag="VQU30_001984"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000251933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit D"
                     /protein_id="HET2448027.1"
                     /translation="MVRLNVKPTRMELNNLKERLKTAERGHKLLKDKRDELMRRFISL
                     IRENNRLRKEVESYLIDNLKSFAVAKSLKNSLMVEELFSIPSKEIELFIEKENIMSVT
                     VPRMHMNITSQNENSEYSYLSSNSEMDDVFATMNSLIDKLLRLAEVEKTCQLMADEIE
                     KTRRRVNGLEYSIIPNLSETIHYIELKLEEAERANLVRIMKVK"
     gene            complement(7496..8481)
                     /locus_tag="VQU30_001985"
                     /pseudo
     CDS             complement(7496..8481)
                     /locus_tag="VQU30_001985"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000436393.1"
                     /note="frameshifted; incomplete; missing N-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
BASE COUNT         2763 a         1211 c         1733 g         2774 t
ORIGIN      
        1 ataaaagtta tggatgagcg ttttggacat tctatttata tttatgaatc ggaaacattg
       61 tcggataatc aagatgaaat acctatcaaa ttaacgaatc attctttaat tgaaccattt
      121 gaattattga cagaaatgta tgctctgccc aaatattatg agaaagatcc tacacctgta
      181 ttagcaccat tttactttac attttttgga atgatggttg ctgatttagg ctatggttta
      241 ctattgtttt taggaacaat gttagcatta aaaatttttc atctaccttc agaaactaag
      301 agatttttaa aattctttaa tatattaggg gtagccgttg caatttgggg tggaatctat
      361 ggctcatttt ttggatatga gttgccattt catctgatat ctacaacctc tgatgtcatg
      421 attatattag tagtgtcagt tgtgtttggg tttattacag tatttgcagg tttgttagct
      481 tcaggactac aaaaagtaag aatgaagaaa tatgcagaag catataattc aggatttgtg
      541 tggtgtgtta ttctgcttgg cttgttattt attgctgtcg gaatgttgat gcctgatatg
      601 agactgttat ttgtattagg gaaatgggta tctattttta atgctgtggg aattttggtt
      661 gtttctatta ttcaagccaa aagcttgtca ggtattggag caggattgtt taatctatat
      721 aacatttcat cttatatagg tgatttagtt agtttcactc gattgatggc attaggatta
      781 tctggagcaa gtatagcatc agctttcaat ttaattgttg gtttgtttcc gggaacattg
      841 gctaaactaa caattggatt agtattattc attcttttac atgcgatcaa tatttttcta
      901 tcgttactat caggatatgt tcatggagca cgtctgatat ttgttgaatt ttttggtaag
      961 ttttatgagg gtggaggaaa accatttcaa cctttgaagg cttctgagaa atatattaag
     1021 gttattacaa agaattaatg gaggatatat ataatggaac atttagcaac ttatttttca
     1081 acctatggag gagctttctt cgctgcattg ggaattgtat tggcggttgg attaagtggt
     1141 atggggtctg cttatggagt tggtaaggct gggcaatctg ccgcagcttt actgaaagaa
     1201 cagccagaaa agtttgcctc tgctttgata ttgcaattac tgcccggaac acaaggatta
     1261 tatggttttg ttattggaat tttgatttgg ttgcaattaa ctccagaact tcctttagaa
     1321 aaaggcgttg cttatttctt tgtagctctt ccaattgcta ttgtaggata cttttcggct
     1381 aagcatcaag gaaatgtagc agtagcggga atgcaaatct tggctaaaag accaaaagaa
     1441 ttcatgaagg gagcaatttt ggctgccatg gtagaaacct atgcaattct tgcctttgtc
     1501 gtatcattca ttttgaccct tcgtgtataa gaaattaatt tgctattcaa aggaggtgtc
     1561 taaatgagca atttagaaaa cttacgagag tctgttattg aacaagctca tgaaaaaggg
     1621 cgtatgaaat tattggattc caaaaagaag attgatgatg aatttgaaat gcaaaagtcg
     1681 gtcattgtaa agaaaaaaga agtggaacat gaacgaaagt taaaagaatt acaacagaaa
     1741 tatcaaataa tttttcaaca attaaaaaat aaggaacgcc aatcaacgtt agtatcaaaa
     1801 cagaaaatat taaaagaact ttttcaatct gctttaatag aaatggaatc ttggagtgca
     1861 gataaagaaa tggagttcat ctatcgaatt ctggaacgat attcacaaca agaggtcata
     1921 gtaacttttg gggagcggac tttagctaaa ttcaatctgg aacaattaga gaaattgaaa
     1981 ttctcttttc caaatcattt atttagtgaa cagcctatct caaatgaatc aggcttactt
     2041 atttcaatag gtaaaattga tgataactat ttgtataaaa cattaattgg atcgatttct
     2101 aaggaagaaa gttcaagtat cgcaaatcaa atttttatca attaaggatg aaattggtta
     2161 atccttctta gaaatttgga gtattccaat aaaattagaa aggtatttta tggatactaa
     2221 tcttttttca aaaataaata cgacgatttc ggtaaaagaa aacgatttta ttacagaaga
     2281 taaatttcaa aaaattatac aatccaaaga tacggagaca atggcattta tcttagaagc
     2341 aactccctat catttatcga ttgacgtttt agaaaatcct agtcagacag agacttcgct
     2401 aatgacaaaa ttagtcaatg attatagatg ggcctatgct gaaagtccgt ctaataaaat
     2461 tgtgacttta tttgctttac gatatgttta tcataatatc aaagttttat taaaatctaa
     2521 ggcggcaatt aagaaagatt tttctaaatt attaattcca atagggattt ttgatataga
     2581 aagtttaaaa catttagttt cttccttaca ttcagataca cttcctgatt ttatggttca
     2641 tgaagtagaa tcaatttgga atgagtatga aacttttaat aatattcgtg tacttgatgt
     2701 cggagctgat ctagcatatt ttaaacatct gaaactttta tctaatgagt tagatgaggt
     2761 gctgtctcag gttattgtcg caatgattga cttttataat attattactg taaaacgtgg
     2821 tttatctcaa aataagagtc atggggatat tttacaatta ctttcagatg aaggaagtat
     2881 ttctgctaaa gaatttatat acattgtaga aaatcaagaa atatttgtgt ggttcaataa
     2941 aataaatcca agcttagatt caatcttttc aacttatgaa ttgaagatgc aggacgcaac
     3001 aatttcatct tctgagttag aatttttatg tgatttatta ttgtataaaa ttttagatca
     3061 aggaaggtac aatgtagatg ggccgttagt acttgctaga tatttattgg gatgtgagtt
     3121 tgaagtaaag aatctcagaa tgattatatc agctcttcaa aatacaattc cctttggatc
     3181 aataaaagaa aggatacgcc cgcattatgg aagctaataa gtataaaatt ggcataattg
     3241 gtagccgtga tattatttta ccctttagca tgattgggtt tgatatattt cctgcctatc
     3301 aagaacaaga agctataaat actctaagaa aattagccca atctgattat ggtgtcattt
     3361 atatcactga agacattgct tcaatgatat tagatacaat tcgccattat gattctcaag
     3421 ttgtgcctgc tattatttta ttaccgactc ataaacaagg tttaaattta ggattaaaac
     3481 gtatagagga taatgtggag aaagcagtag gacacaatat tttataataa tgtacaaaat
     3541 tgtctgtaat attattctat aatttttgga cttagtaagg agaataactt tgactcaagg
     3601 gaagattata aaagtatcgg gacctctagt tattgcatca ggtatgcagg aggctaatat
     3661 tcaagatatt tgccgtgtag gtaagctagg gttaatcggt gaaattattg aaatgagaag
     3721 agatcaggca tctatccaag tctatgagga aacatctggt cttggtccgg gagaacctgt
     3781 tgttacaact ggagaacctc tctcggttga attaggacca ggattgattt ctcaaatgtt
     3841 tgatggcata caacgcccat tagatcgatt taaattggct actcataatg attttctagt
     3901 tcgtggggta gaagttccaa gtttggatag agatattaag tggcattttg attccactat
     3961 agcaattggt caaaaagtga gtacgggtga tattctagga actgtcaagg aaaccgaggt
     4021 agttaatcat aaaattatgg ttccttatgg agtatctggc gaagtcgttt ctatcgcatc
     4081 tggcgatttt acaattgatg aagttgtata tgaaataaaa aaattggacg gtagtttcta
     4141 taaaggaacg cttatgcaaa aatggcctgt tcgcaaggcg cgtcctgttt ctaaacgttt
     4201 aatcccagaa gaaccattaa tcacaggtca acgagttatt gatacattct ttccagtaac
     4261 caaaggggga gcagcagctg ttcctggacc gtttggagca ggaaagacag ttgtacaaca
     4321 ccaagtagct aaattttcca atgttgatat tgttatttat gtcggttgtg gagaacgtgg
     4381 aaatgaaatg acggatgtac tgaatgagtt tcctgagttg attgacccta ataccggaca
     4441 atcaattatg caacggacag ttctgattgc taatacttca aatatgcctg ttgctgctcg
     4501 tgaggcttca atttatacag gaattaccat ggctgagtat tttcgtgata tgggctactc
     4561 tgtcgccatt atggctgatt cgacttcacg ttgggcagaa gcactacgtg aaatgtcagg
     4621 acgtctagaa gaaatgcctg gtgatgaggg ttatcctgct tatctgggaa gtcgtatcgc
     4681 tgaatattat gaaagagcgg gacgttctca ggttctaggg attccagaac gtgaaggaac
     4741 tattactgct attggagctg tatcgccacc cggtggagat atttcagaac cagttactca
     4801 aaacacttta cggattgtga aagttttttg ggggcttgat gctccgttgg cacagagacg
     4861 tcattttcct gcaattaact ggcttacatc ttattcactc tataaagaca gtgtgggaat
     4921 ttatatagat ggtaaagaga agacagattg gaatagtaaa ataactcgtg cgatgaacta
     4981 cttacaacgg gaatctagtt tagaggaaat tgttcgtctt gttggaattg attctctgtc
     5041 tgataatgaa cgactaacga tggaaattgc taaacaaatt cgagaagatt atttgcaaca
     5101 gaatgctttt gattcagtag atacattcac ttcgtttgca aaacaagaag caatgctaag
     5161 taatatccta acttttgctg atcaggcaaa tcatgcttta gagttaggtt cttactttac
     5221 agagattatg gaaggtaccg tggcagttcg agaccgtatg gcgcgaagta aatatgtttc
     5281 agaagataga ttagatgaaa tcaaaattat ttcaaatgag attacacatc aaattcattt
     5341 gatattagaa acaggaggtc tataaatgag tgttataaaa gaatacagaa ctgctagtga
     5401 agttgttggg cctcttatga ttgttgaaca agtaaataat gtgtcttaca atgagttagt
     5461 tgaaattcaa cttcataatg gagaaattcg tcgtggacaa gttttagaga ttcacgaaga
     5521 taaagcaatg gttcaacttt ttgaaggatc tagtggaata aatttagaaa agtctaaaat
     5581 tcgttttgct ggtcatgcac tagaattggc tgtatctgag gatatggttg gtcgtatttt
     5641 taatgggatg ggaaaaccaa ttgatggtgg accagattta attccagaga aatatttaga
     5701 tattgatggt caagctatta atcctgtatc tagagattat ccagatgaat ttattcagac
     5761 agggatctcc tctattgatc atttgaatac tcttgtacgt ggtcaaaaat taccagtatt
     5821 ttcaggttcg ggcttacctc ataatgaatt agcagctcag atagcaagac aagcgactgt
     5881 tttaaattct gatgaaaatt ttgcggttgt atttgcagca atgggtatta cttttgaaga
     5941 agctgagttt tttatggaag aactcagaaa aacaggagcg atcgatcgtt cagtcttatt
     6001 tatgaacttg gcaaatgatc ctgcaattga gcgtattgca actccccgca ttgctttaac
     6061 cgcggcagag tatctagctt ttgaaaaaga tatgcacgtt ctagttatca tgacggatat
     6121 gactaactat tgtgaagcgt tacgtgaagt ctcggcagcg cgccgtgaag ttccaggtag
     6181 acgaggctat ccgggatatt tatatacaaa tttatcaact ctatatgaaa gggctggtcg
     6241 cttagttggt aaaaaaggtt cagtgacaca gattcctatt ttaacaatgc cagaagatga
     6301 cataacacat ccaattcctg atttaactgg atacattact gaagggcaaa ttattttgtc
     6361 tcatgagttg tataatcaag gttatcgtcc accaatcaat gttttatctt ctctctctcg
     6421 attaaaagat aagggatctg gagaaggtaa aactcgtgga gatcatgctc caactatgaa
     6481 tcaactgttt gcagcctatg cccaagggaa aaaggttgaa gagttagcag tagtattagg
     6541 agaatcggct ttatctgatg tagataaatt gtatgtgaga tttacaaagc gttttgaaga
     6601 agagtacatc aaccaaggat tttataaaaa tcgaaatata gaagatacgt tgaatcttgg
     6661 gtgggaatta ctatcaattc ttcctagaac agagttaaaa cgtatcaaag atgatttgct
     6721 tgataaatat ttacctttgg tagaagttta atccagaaat ggagtgatta tctatggtac
     6781 gtttgaatgt aaaaccaact cgtatggaat tgaataactt aaaggaacgt ttgaaaacag
     6841 ctgaacgtgg acataagtta ttaaaggata aaagagatga attgatgagg cgatttattt
     6901 ctttgattcg tgagaataat cgacttcgga aagaagtaga aagttatcta attgataatc
     6961 taaaatcttt tgcagttgct aaatcattaa agaactctct aatggtggag gaattatttt
     7021 caattccatc gaaagaaatt gaattattta ttgagaaaga aaatatcatg agtgtaacag
     7081 ttcctagaat gcatatgaat attacttctc aaaatgagaa cagtgaatac agctatttat
     7141 cttctaatag tgaaatggat gatgtatttg ctacaatgaa tagtttaatt gataaattac
     7201 taagactggc agaagttgaa aaaacgtgtc agttaatggc tgatgaaata gaaaaaacac
     7261 gtagacgtgt aaatggttta gaatattcga ttattccaaa cttgtcggaa actattcatt
     7321 atatagaatt gaaactagag gaggcagaaa gagccaattt agttcgtatt atgaaagtga
     7381 agtagttcct ttatttagat ttttaattag atgaacaaat atcagcttgg ataaggcggt
     7441 aagcctttct aagctttttt aggctctttg tcaactgtag tgggttgaaa aaaagctaag
     7501 ctcgagaaag gacaaatttc gtcctttctt ttttgatatt cagggcgata aaaatccgtt
     7561 ttttgaagtt ttcaaagttc cgaaaaccaa aggcattgcg cttgataagt ttgatgagat
     7621 tattggtcgc ttccaatttg gcgttagaat agtgtagttg aagggcgttg acgattttct
     7681 ctttgtcctt tagaaaggtt ttaaagacag tctgaaaaag aggatgaacc tgctttagat
     7741 tgtcctcaat gagtccgaaa aatttctccg gttccttatt ctgaaagtga aacagcaaga
     7801 gttgatagag ctgatagtga tgtttcaagt cttgtgaata gctcaaaagc ttgtttaaaa
     7861 tctctttatt ggttaaatgc atacgaaaag tagggcgata aaaatgttta tcgctgagtt
     7921 tacgactatc ctgttgtatg agcttccagt agcgcttgat agccttgtat tcatgagact
     7981 ttcgatccaa ttgattcatg atttgaacac gcacacgact catagcacgg ctaagatgtt
     8041 gtacaatgtg aaagcgatcc aacacgattt tagcacatgg gaaaagttgt ctagctaagt
     8101 catagtaagg actaaacata tccatagtaa taattttgac gcgacatcgg acggctctat
     8161 catatttaag aaagtgatct cggatgacag cttgtgttct accctcaaga acagtgatga
     8221 tattgagatt gttaaaatct tgcgcaatga agctcatctc catctcccga ttgaaacagt
     8281 cactccccgg actgtttcaa cgtcccaaga cataatctca ggcagatttc taaaattaca
     8341 ctcaaagtgg aagtcattga gcttacgaat aacagttgaa gttgagatgg aaagctgatg
     8401 ggcaatatca gtcatagaaa tcttttcaat taacttttga gcaatctttt ggttgatgat
     8461 acgagggatt tggtgattat t
//
LOCUS       DAVBBO010000075         8107 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ST1
            SAMEA2066453-rid20184263.denovo.075, whole genome shotgun sequence.
ACCESSION   DAVBBO010000075 DAVBBO010000000
VERSION     DAVBBO010000075.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2066453
            Sequence Read Archive: ERR351777
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 8107)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8107)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980402.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980402.1
            Genome Coverage       :: 176x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:17:33
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,141
            CDSs (total)                      :: 2,104
            Genes (coding)                    :: 1,953
            CDSs (with protein)               :: 1,953
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 16S)
            partial rRNAs                     :: 1 (23S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 151
            CDSs (without protein)            :: 151
            Pseudo Genes (ambiguous residues) :: 0 of 151
            Pseudo Genes (frameshifted)       :: 73 of 151
            Pseudo Genes (incomplete)         :: 76 of 151
            Pseudo Genes (internal stop)      :: 40 of 151
            Pseudo Genes (multiple problems)  :: 32 of 151
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8107
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2066453-rid20184263.denovo.075"
                     /strain="ST1"
                     /db_xref="taxon:1313"
     gene            120..497
                     /locus_tag="VQU30_001986"
     CDS             120..497
                     /locus_tag="VQU30_001986"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001833802.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PD-(D/E)XK nuclease family transposase"
                     /protein_id="HET2448028.1"
                     /translation="MICQFIRDMLDLPAKNVTILEGSNIHVLPSMPYSAQDFYTSIDV
                     LAELDNGIQVIIEIQVHHQNFFINRLWAYLCSQVNQNLEKIRQREGDTHQSYKQIALV
                     YAIAIVDSNYFSDDLAFHSFIVK"
     gene            732..2123
                     /locus_tag="VQU30_001987"
     CDS             732..2123
                     /locus_tag="VQU30_001987"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013193417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide deacetylase family protein"
                     /protein_id="HET2448029.1"
                     /translation="MNKSRLGRGRHGKTRHVLLALIGILAISICLLGGFIAFKIYQQK
                     SFEQKIESLKKEKDDQLSEGNQKEHFRQGQAEVIAYYPLQGEKVISSVRELINQDVKD
                     KLESKDNLVFYYTEQEESGLKGVVNRNVTKQIYDLVAFKIEETEKTSLGKVHLTEDGQ
                     PFTLDQLFSDASKAKEQLIKELTSFIEDKKIDQDQSEQIVKNFSDQDLSAWNFDYKDS
                     QIILYPSPVVENLEEIALPVSAFFDVIQSSYLLEKDAALYQSYFDKKHQKVVALTFDD
                     GPNPATTPQVLETLAKYDIKATFFVLGKNVSGNEDLVKRIKSEGHVVGNHSWSHPILS
                     QLSLDEAKKQITDTEDVLTKVLGSSSKLMRPPYGAITDDIRNSLDLSFIMWDVDSLDW
                     KSKNEASILTEIQHQVANGSIVLMHDIHSPTVNALPRVIEYLKNQGYTFVTIPEMLNT
                     RLKAHELYYSRDE"
     gene            2237..3079
                     /locus_tag="VQU30_001988"
     CDS             2237..3079
                     /locus_tag="VQU30_001988"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397460.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldo/keto reductase"
                     /protein_id="HET2448030.1"
                     /translation="MNTYQLNNGVEIPVLGFGTFKAKDGEEAYRAVLEALKAGYRHID
                     TAAIYQNEESVGQAIKDSGVPREEMFVTTKLWNSQQTYEQTRQALEKSIEKLGLDYLD
                     LYLIHWPNPKPLRENDAWKTRNAEVWRAMEDLYQEGKIRAIGVSNFLPHHLDALLETA
                     TIVPAVNQVRLAPGVYQEQVVAYCREKGILLEAWGPFGQGELFDSKQVQEIAANHGKS
                     IAQIALAWSLAEGFLPLPKSVTTSRIQANLDCFGIELSHEERETLKTIAVQSGAPRVD
                     DVDF"
     gene            3352..4113
                     /locus_tag="VQU30_001989"
     CDS             3352..4113
                     /locus_tag="VQU30_001989"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor Tu"
                     /protein_id="HET2448031.1"
                     /translation="MDNLYLVKDDSQLATFRDFVVRNTEKLKDYQSFLKNELAVCDLP
                     QAVIWSDFNAATQIIRESAVPAYTNNRRMVMAPDLAVWKELYLYQLMDYECSQQTQAI
                     ESHYHSLSENFLLQIVGHELAHWSEHFLDDFDGYDSYIWFEEGMVEYISRKYFLTEEE
                     FQAEKICNQSLVELFQKKYGWHSLNDFGSSTYDKNYASIFYEYWRSFLTVDKLVENLG
                     SVQAVLDSYHLWANTEKTFPLLDWFVQQKLIEKEI"
     gene            4483..5400
                     /gene="glyQ"
                     /locus_tag="VQU30_001990"
     CDS             4483..5400
                     /gene="glyQ"
                     /locus_tag="VQU30_001990"
                     /EC_number="6.1.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018163989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine--tRNA ligase subunit alpha"
                     /protein_id="HET2448032.1"
                     /translation="MSKKLTFQEIILTLQQFWNDQGCMLMQAYDNEKGAGTMSPYTFL
                     RAIGPEPWNAAYVEPSRRPADGRYGENPNRLYQHHQFQVVMKPSPSNIQELYLESLEK
                     LGINPLEHDIRFVEDNWENPSTGSAGLGWEVWLDGMEITQFTYFQQVGGLATGPVTAE
                     VTYGLERLASYIQEVDSVYDIEWADGVKYGEIFIQPEYEHSKYSFEISDQEMLLENFD
                     KFEKEAGRALEEGLVHPAYDYVLKCSHTFNLLDARGAVSVTERAGYIARIRNLARVVA
                     KTFVAERKRLGYPLLDEETRVKLLAEDAE"
     gene            5660..7696
                     /locus_tag="VQU30_001991"
     CDS             5660..7696
                     /locus_tag="VQU30_001991"
                     /EC_number="6.1.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012000066.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine--tRNA ligase subunit beta"
                     /protein_id="HET2448033.1"
                     /translation="MTKNLLVELGLEELPAYVVTPSEKQLGEKMAAFLKENRLSFEAI
                     QTFSTPRRLAVRVTGLSDKQSDLTEDFKGPAKKIALDSDGNFTKAAQGFVRGKGLTVE
                     DIEFREIKGEEYVYVTKEEVGQAVEAIVPGVVDVLKSLTFPVSMHWAGNSFEYIRPVH
                     TLTVLLDEQEFDLDFLDIKGSRVSRGHRFLGKETKIQSALSYEEDLRKQFVIADPCER
                     EQMIVDQIKEIEAKHGVRIEIDADLLNEVLNLVEYPTAFMGSFDAKYLEVPEEVLVTS
                     MKEHQRYFVVRDQDGKLLPNFISVRNGNAERLKNVIKGNEKVLVARLEDGEFFWREDQ
                     KLVISDLVEKLNNVTFHEKIGSLREHMIRTGQITVLLAEKAGLSVDETVDLARAAAIY
                     KFDLLTGMVGEFDELQGIMGEKYTLLAGETPAVAAAIREHYMPTSAEGELPESKVGAV
                     LAIADKLDTILSFFSVGLIPSGSNDPYALRRATQGVVRILDAFGWHIAMDELIDSLYA
                     LKFDSLTYENKAEVMDFIKARVDKMMGSTPKDIKEAVLAGSNFVVADMLEAASALVEV
                     SKEEDFKPSVESLSRAFNLAEKAEGVATVDSELFENDQEKALAEAVETLVLSGPASQQ
                     LKQLFALSPVIDAFFENTMVMAEDQAVRQNRLAILSQLTKKAAKFACFNQINTK"
     gene            7738..7995
                     /locus_tag="VQU30_001992"
     CDS             7738..7995
                     /locus_tag="VQU30_001992"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002901318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF896 family protein"
                     /protein_id="HET2448034.1"
                     /translation="MDPKKIARINELAKKKKTEGLTPEEKVEQAKLREEYIEGYRRAV
                     RHHIEGIKIVDEEGNDVTPEKLRQVQREKGLHGRSLDDPNS"
BASE COUNT         2554 a         1431 c         1794 g         2328 t
ORIGIN      
        1 gctttctttt ccgaataaat agatagaagc atagaatcta gcaaacctag atttaaaaat
       61 gtgctataat agaaggagga aaaggaggat tctcagacat ccaggtatca gcccaactaa
      121 tgatttgtca atttatccgc gatatgctgg acttgccagc aaaaaatgtg acgattttgg
      181 agggaagtaa cattcacgtc ttgccttcca tgccctactc agcgcaagat ttctatacta
      241 gtatagacgt cttggcggag ttagataatg gaatccaagt tatcatcgaa attcaggttc
      301 atcatcagaa ttttttcatc aatcgcctat gggcttatct gtgcagtcag gttaatcaaa
      361 acctagaaaa aattcgccaa cgtgaaggtg atacccacca gagctacaaa caaatcgcac
      421 tagtatacgc tatcgcaatt gtcgatagta attacttctc agatgaccta gcttttcata
      481 gttttatagt aaaatgaaat gagaacagga caaatcgatc aggacagtca aatcgatttc
      541 taacaatgtt ttagaagtat aggtctacta ttctagcttc aatctactag aaattccata
      601 gatagaaaac tacataatct ctacagatac ggatgttgga gttgatgtaa gatgctttgg
      661 cttgctagag gaattgtgga ttgccaaatt gtatcattga aattattgct caaatttgtt
      721 atgatataaa tatgaataaa agtagactag gacgtggcag acacgggaaa acgagacatg
      781 tattattggc tttgattggt attttagcaa tttctatttg cctattaggc ggatttattg
      841 cttttaagat ctaccagcaa aaaagttttg agcaaaagat tgaatcgctc aaaaaagaga
      901 aagatgatca attgagtgag ggaaatcaga aggagcattt tcgtcagggg caagccgaag
      961 tgattgccta ttatcctctc caaggggaga aagtgatttc ctctgttagg gagctgataa
     1021 atcaagatgt taaggacaag ctagaaagta aggacaatct tgttttctac tatacagagc
     1081 aagaagagtc aggtttaaag ggagtcgtta atcgtaatgt gaccaaacaa atctatgatt
     1141 tagttgcttt taagattgaa gagactgaaa agaccagtct aggaaaggtt cacttaacag
     1201 aagatgggca accttttaca cttgaccaac tgttttcaga tgctagtaag gctaaggaac
     1261 agctgataaa agagttgacc tccttcatag aggataaaaa aatagatcaa gaccagagtg
     1321 agcagattgt aaaaaacttc tctgaccaag acttgtctgc atggaatttt gattacaagg
     1381 atagtcagat tatcctttat ccaagtcctg tggttgaaaa tttagaagag atagccttgc
     1441 cagtatctgc tttctttgat gttatccaat cttcgtactt actcgaaaaa gatgcggcct
     1501 tgtaccaatc ttactttgat aagaaacatc aaaaagttgt cgctctaacc tttgatgatg
     1561 gtccaaatcc agcaacgacc ccgcaggtat tagagaccct agctaaatat gatattaaag
     1621 cgactttctt tgtgcttggg aaaaatgttt ctgggaatga ggacttggtg aagaggataa
     1681 aatctgaagg tcatgttgtt ggaaaccata gttggagcca tccgattctc tcgcaactct
     1741 ctcttgatga agctaaaaag cagattactg atactgagga tgtgctaact aaagtgctgg
     1801 gttctagttc taaactcatg cgtccacctt atggtgctat tacagatgat attcgcaata
     1861 gcttggattt gagctttatc atgtgggatg tggatagtct ggactggaag agtaaaaatg
     1921 aagcatctat tttgacagaa attcagcatc aagtagctaa cggctctatc gttttgatgc
     1981 atgatattca cagtccgaca gtcaatgcct tgccaagggt cattgagtat ttgaaaaatc
     2041 aaggttatac ctttgtgacc ataccagaga tgctcaatac tcgcctaaaa gctcatgagc
     2101 tgtactatag tcgtgatgaa taagcaagaa aaaataggtc tgttagatat ttgacagact
     2161 tattttttac agaatatagt actacttaaa aaatgtttta tgctataatt gatgaataaa
     2221 atagaaggag aagcatatga atacctatca attaaataat ggagtagaaa ttccagtatt
     2281 gggatttgga acttttaagg ctaaggatgg agaagaagcc tatcgtgcag tgttagaagc
     2341 cttgaaggct ggttatcgtc atattgatac ggcggcgatt tatcagaatg aagaaagtgt
     2401 tggtcaagca atcaaagata gcggagttcc acgtgaagaa atgttcgtaa ctaccaagct
     2461 ttggaatagt cagcaaacct atgagcaaac tcgtcaagct ttggaaaaat ctatagaaaa
     2521 actgggcttg gattatttgg atttgtattt gattcattgg ccgaacccaa aaccgctcag
     2581 agaaaatgac gcatggaaaa ctcgcaatgc ggaagtttgg agagcgatgg aagacctcta
     2641 tcaagaaggg aaaatccgtg ctatcggcgt tagcaatttt cttccccatc atttggatgc
     2701 cttgcttgaa actgcaacta tcgttcctgc ggtcaatcaa gttcgcttgg cgccaggtgt
     2761 gtatcaagaa caagtcgtag cttactgtcg tgaaaaggga attttattgg aagcttgggg
     2821 gccttttggt cagggagaac tatttgatag caagcaagtg caagaaatcg cagcaaatca
     2881 cggaaaatcg attgctcaga tagccttggc ctggagcttg gcagaaggat ttttaccact
     2941 tccaaaatct gtcacaacct ctcgtattca agctaatctt gattgctttg gaattgaact
     3001 gagtcatgag gagagagaaa ccttaaaaac gattgctgtt caatcgggtg ctccacgagt
     3061 tgatgatgtg gatttctaga aaatcataaa aagaattgta cattattcta atttttgata
     3121 taatagtcag caggaaagaa agtcttatgg cgttcttcaa gcgagcttgg gatagtggga
     3181 gccaagtagg gcaaaataat gagctggcgc tttctgtagt attttcaaaa acaatgaagt
     3241 aataaattag ggtggaaccg cgtttctgac gcccctaggt taaatcaacc taggattgtc
     3301 ggacgcggtt cttttgctta ttcagtctat tgtgtgaaag aaaggagagc cgtggacaac
     3361 ctttatcttg taaaagacga tagtcaacta gctacatttc gtgattttgt agtaagaaat
     3421 actgaaaagt tgaaagatta tcaatctttt ttaaagaatg aacttgcagt ctgtgattta
     3481 ccgcaagccg ttatttggtc agattttaat gctgctacac agattattag ggaaagcgct
     3541 gttccagcct atacaaataa tagacgaatg gttatggcgc ctgatttagc tgtttggaaa
     3601 gagttgtatt tgtatcaatt gatggactac gagtgttctc agcaaactca agcaatagaa
     3661 agtcactatc attctttatc tgaaaatttc ctcttacaga ttgtaggaca tgagttagct
     3721 cattggtcgg agcatttttt agatgatttt gatggttatg actcttatat ctggttcgaa
     3781 gaggggatgg ttgaatatat tagtcgcaag tatttcttga cagaagagga atttcaagcg
     3841 gaaaaaattt gtaatcaatc tctcgtagaa ctttttcaga agaagtatgg ttggcattca
     3901 ttgaatgatt ttggttcttc gacttatgat aagaactatg caagtatttt ttatgaatac
     3961 tggcgcagct ttttgacagt agataagttg gtagaaaatt taggtagtgt acaagcggtc
     4021 ttagattctt atcatttatg ggcaaataca gaaaaaactt ttcccttgtt agattggttt
     4081 gttcagcaga aattaattga aaaagaaata taaaaactaa aggagtaaac aatgtctaag
     4141 aaattgacat ttcactgcgt cagtggcaga aacctcctta cagtcggact gccccacgct
     4201 cagcactaga gtgcctgagc tagacgcagt actaactcgt cttgcctcgt atgatcgacg
     4261 aggcagactc atgtcgcaag taattatttt ttattaagga gtaaacaatg tctaagaaat
     4321 taacatttca ctgcatcagt ggcagaaacc tccttacagt cggactgccc cacgctcagc
     4381 accctagtgc tgagctagac gcagtactaa ctcgtcttgc ctcgtataat cgacgaggca
     4441 gactcgtgtc gcaagaaatc attttttatt aaggagtaaa caatgtctaa gaaattaaca
     4501 tttcaagaaa ttattttgac tttgcaacaa ttttggaatg accaaggttg tatgcttatg
     4561 caggcttatg acaatgaaaa aggtgcgggg acaatgagtc cttacacttt ccttcgtgct
     4621 atcggacctg agccatggaa tgcagcttat gtagagccat cacgtcgtcc tgctgacggt
     4681 cgttatgggg aaaaccctaa ccgtctctac caacaccacc aattccaggt ggtcatgaag
     4741 ccttctccat caaatatcca agaactttac cttgagtctt tggaaaaatt gggaatcaat
     4801 cctttggagc acgatattcg ttttgttgag gacaactggg aaaacccatc aactggttca
     4861 gctggtcttg gttgggaagt ttggcttgac ggaatggaaa tcactcagtt cacttatttc
     4921 caacaagtcg gtggattggc aactggccct gtgactgcgg aagttaccta tggtttggag
     4981 cgcttggctt cttacattca agaagtagac tctgtctatg atatcgagtg ggctgatggt
     5041 gtaaaatacg gagaaatctt tatccagcct gagtatgagc actcaaaata ttcatttgaa
     5101 atttcggacc aagaaatgtt gcttgaaaac tttgataagt ttgaaaaaga agctggtcgt
     5161 gcattagaag aaggcttggt acaccctgcc tatgactatg ttctcaaatg ttcacatacc
     5221 tttaatctgc ttgacgcgcg tggtgccgta tctgtaacag agcgtgcagg ctatatcgct
     5281 cgtatccgta acttggcccg tgttgtagcc aaaacctttg ttgcagaacg caaacgccta
     5341 ggttacccac ttttggatga agaaacacga gttaaacttt tagcagaaga cgcagaatag
     5401 tgagtaatac tgtactctaa aatcgttaga ggcaagtcga agacttgcta gagggatatg
     5461 caccgccgta ctgttatgtg gggatttttg aaaccttagg ttcaaaaatc agtcagctaa
     5521 atccactttg atgagattgt tggaaatctt gataaattta gcattggatt tccatacaga
     5581 ctcacagagt tagttagcga cgtccccagt acctaaggtg catatcaaaa aagattgaag
     5641 aaaatgtaaa ggaaaaaaca tgacaaaaaa cttattagta gaactcggtc ttgaagaatt
     5701 accagcctat gttgtcacac caagtgaaaa acaactaggc gaaaaaatgg cagccttcct
     5761 caaggaaaac cgcctgtctt ttgaagccat tcaaaccttc tcaacaccac gtcgtttggc
     5821 tgttcgtgtg actggtttat cagacaaaca gtctgatttg acagaagatt tcaagggacc
     5881 agcaaagaaa attgccttgg atagtgatgg aaactttacc aaagcagctc aaggatttgt
     5941 ccgtggaaaa ggcttgactg ttgaagatat cgaattccgt gaaatcaagg gtgaagaata
     6001 tgtctatgtc actaaggaag aagttggtca agcagttgaa gccattgttc ctggtgttgt
     6061 agatgtcttg aagtcattga ctttccctgt cagcatgcac tgggctggaa atagctttga
     6121 atacattcgt cctgtccaca ctttaactgt tctcttggat gagcaagagt ttgacttgga
     6181 tttccttgat atcaagggaa gtcgtgtgag ccgtggccat cgtttcttgg ggaaagaaac
     6241 caaaattcag tcagcattga gctatgaaga agaccttcgt aagcagtttg taatcgcaga
     6301 tccatgtgaa cgtgagcaaa tgattgttga ccaaatcaag gaaattgagg caaaacatgg
     6361 tgtacgtatc gaaattgatg cggatttgct gaatgaagtc ttgaatttgg ttgaataccc
     6421 aactgccttc atgggaagtt ttgatgctaa ataccttgaa gttccagaag aagtcttggt
     6481 gacttctatg aaggaacacc agcgttactt tgttgttcgt gatcaagatg gaaaactctt
     6541 gccaaacttc atttctgttc gtaacggaaa cgcagagcgt ttgaaaaatg tcattaaagg
     6601 aaatgaaaaa gtcttggtag cccgcttgga agacggagaa ttcttctggc gtgaagacca
     6661 aaaattggtg atttcagatc ttgttgaaaa attaaacaat gtcaccttcc atgagaagat
     6721 tggttccctt cgtgaacaca tgattcgtac gggtcaaatc actgtacttt tggcagaaaa
     6781 agctggtttg tcagtggatg aaacagttga ccttgctcgt gcagcagcca tttacaagtt
     6841 tgacttattg acaggtatgg ttggtgaatt tgacgaactc caaggaatta tgggtgaaaa
     6901 atacaccctt cttgctggtg aaactccagc ggtggcagct gctattcgtg aacactacat
     6961 gcctacatca gctgaaggag aacttccaga gagcaaggtc ggcgcagttc tagccattgc
     7021 agacaaattg gatacgattt tgagtttctt ctcagtagga ttgattccat caggttctaa
     7081 tgacccttat gcccttcgtc gtgcaactca aggtgtggtt cgtatcttgg atgcctttgg
     7141 ttggcacatt gctatggatg agctgattga tagcctttat gcattgaaat ttgacagttt
     7201 gacttatgaa aataaagcag aggttatgga ctttatcaag gctcgtgttg ataagatgat
     7261 gggctctact ccaaaagata tcaaggaagc agttcttgca ggttcaaact ttgttgtggc
     7321 agatatgttg gaagcagcaa gtgctctcgt agaagtaagc aaggaagaag attttaaacc
     7381 atctgttgaa tcactttctc gtgcctttaa cctggctgag aaggcagaag gggttgctac
     7441 agttgattca gaactatttg agaatgacca agaaaaagct ttggcagaag cagtagaaac
     7501 actcgtttta tcaggacctg caagtcagca attgaaacaa ctctttgcgc ttagcccagt
     7561 cattgatgct ttctttgaaa atactatggt aatggctgaa gatcaggctg tccgtcaaaa
     7621 tcgtttggca atcttgtcac aactaaccaa gaaagcagct aagtttgctt gttttaacca
     7681 aattaacact aaataaaatt tgataaacgg actttatctt attacaaagg agaagaaatg
     7741 gatccgaaaa aaattgctcg tatcaatgag cttgctaaaa agaaaaaaac agaaggctta
     7801 acaccagaag aaaaagtgga acaagccaaa ctacgtgagg agtacatcga aggttatcgc
     7861 cgcgctgttc gtcaccacat tgaaggaatc aaaattgtgg acgaagaagg aaacgatgtt
     7921 acaccagaaa aactacgcca agtacaacgt gaaaaaggat tacatggccg tagtcttgat
     7981 gacccaaatt cataatatgt actctttctt ttaacaaaga tagatgaaac gataacaaag
     8041 agactagcag tttgtgtttg ctagtctttt ttcgctaaaa aaggaaccat aatggttcct
     8101 aaaaact
//
LOCUS       DAVBBO010000076         7893 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ST1
            SAMEA2066453-rid20184263.denovo.076, whole genome shotgun sequence.
ACCESSION   DAVBBO010000076 DAVBBO010000000
VERSION     DAVBBO010000076.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2066453
            Sequence Read Archive: ERR351777
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 7893)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7893)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980402.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980402.1
            Genome Coverage       :: 176x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:17:33
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,141
            CDSs (total)                      :: 2,104
            Genes (coding)                    :: 1,953
            CDSs (with protein)               :: 1,953
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 16S)
            partial rRNAs                     :: 1 (23S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 151
            CDSs (without protein)            :: 151
            Pseudo Genes (ambiguous residues) :: 0 of 151
            Pseudo Genes (frameshifted)       :: 73 of 151
            Pseudo Genes (incomplete)         :: 76 of 151
            Pseudo Genes (internal stop)      :: 40 of 151
            Pseudo Genes (multiple problems)  :: 32 of 151
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7893
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2066453-rid20184263.denovo.076"
                     /strain="ST1"
                     /db_xref="taxon:1313"
     gene            101..1078
                     /locus_tag="VQU30_001993"
     CDS             101..1078
                     /locus_tag="VQU30_001993"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002206301.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HET2448035.1"
                     /translation="MLKLGVIGTGAISHHFIEAAHTSGEYQLVAIYSRKLETAATFAS
                     RYQNIQLFDQLEVFFKSSFDLVYIASPNSLHFAQAKAALSAGKHVILEKPAVTQPQEW
                     FDLIQTAEKNNCFIFEAARNYHEKAFTTIKNFLADKQVLGADFNYAKYSSKMPDLLAG
                     QTPNVFSDRFAGGALMDLGIYPLYAAVRLFEKANDATYHAQQLDNSIDLNGDGILFYP
                     DYQVHIKAGKNITSNLPCEIYTTDGTLTLNTIEHIRSAIFTDHQGNQVQLPIQQAPHT
                     MTEEVAAFAHMIQQPDLNLYQTWLYDAGSVHELLYTMRQTAGVRFEAEK"
     gene            1075..2157
                     /locus_tag="VQU30_001994"
     CDS             1075..2157
                     /locus_tag="VQU30_001994"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007521532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HET2448036.1"
                     /translation="MKTKLPTEWQELSDQLGFQEFTPIQTQLFELLLAGENLLGVSQT
                     GTGKTLAYLLPSLLRLQKKKAQQLLILAPNTELAGQIFDVCKTWAEAIGLTAQLFLSG
                     SSQKRQIERLKKGPEILIGTPGRIFELIKLKKIKMMNVETIILDEFDQLLDDSQIHFV
                     EKITHYAPRDHQLVYMSATTKFDQEKIVPNTRTIDLSDQKLDNIQHFYMQVDQRHRVD
                     MLRKLAHVEDFRGLVFFNSLSDLGNAEEKLQYRDILAVSLASDVNVKFRKIILEKFKD
                     NQLTLLLATDLLARGIDIDSLECVVNFDIPRDSETYTHRAGRTGRMGKEGYVITLVTH
                     PEEIKKLKKFASIREIVLKNQELYIK"
     gene            complement(2221..3270)
                     /locus_tag="VQU30_001995"
                     /pseudo
     CDS             complement(2221..3270)
                     /locus_tag="VQU30_001995"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611577.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS630 family transposase"
     gene            complement(3654..4850)
                     /gene="tuf"
                     /locus_tag="VQU30_001996"
     CDS             complement(3654..4850)
                     /gene="tuf"
                     /locus_tag="VQU30_001996"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014335040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor Tu"
                     /protein_id="HET2448037.1"
                     /translation="MAKEKYDRSKPHVNIGTIGHVDHGKTTLTAAITTVLARRLPSSV
                     NQPKDYASIDAAPEERERGITINTAHVEYETEKRHYAHIDAPGHADYVKNMITGAAQM
                     DGAILVVASTDGPMPQTREHILLSRQVGVKHLIVFMNKVDLVDDEELLELVEMEIRDL
                     LSEYDFPGDDLPVIQGSALKALEGDSKYEDIVMELMNTVDEYIPEPERDTDKPLLLPV
                     EDVFSITGRGTVASGRIDRGIVKVNDEIEIVGIKEETQKAVVTGVEMFRKQLDEGLAG
                     DNVGVLLRGVQRDEIERGQVIAKPGSINPHTKFKGEVYILTKEEGGRHTPFFNNYRPQ
                     FYFRTTDVTGSIELPAGTEMVMPGDNVTIDVELIHPIAVEQGTTFSIREGGRTVGSGM
                     VTEIEA"
     gene            complement(5761..6630)
                     /locus_tag="VQU30_001997"
     CDS             complement(5761..6630)
                     /locus_tag="VQU30_001997"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000348128.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aquaporin family protein"
                     /protein_id="HET2448038.1"
                     /translation="MDFTWALKYATEFLGTAILIILGNGAVANVELKGTKGHQSGWIV
                     IAVGYGMGVMIPALMFGNVSGNHINPAFTLGLAVSGLFPWAQVVPYIIAQVLGAIFGQ
                     ALVVATYRPFYLKTEKPNNILGTFSTISSIDHGTKESRYAATVNGLINEFVGSFVLFF
                     AALGLTKNFFGAEVLQFMKQKAIEAGQTVDFSDLAIKAQVAPHTASGLSVAHLALGFL
                     VMALVTSLGGPTGPALNPARDLGPRLLHAFLPKSVLGEHKGDSKWWYSWVPVVAPIAA
                     AIAAVAVFKFLYL"
     gene            complement(6853..7533)
                     /locus_tag="VQU30_001998"
     CDS             complement(6853..7533)
                     /locus_tag="VQU30_001998"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000248972.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HET2448039.1"
                     /translation="MVPKTATSTETKTITRIIHYVDKVTNQNVKEDVVQPVTLSRTKT
                     ENKVTGVVTYGEWTTGNWDEVISGKIDKYKDPDIPTVESQEVTSDSSDKEITVRYDRL
                     STPDKPTPEKPEIPSPQEPGTPGEPTPEKPIPQPNPEHPSVPTPNPELPNQETPTPDK
                     PTPEPGTPKAETPVNPDPEVPTYETGKREELPNTGTEANATLASAGIMTLLAGLGLGF
                     FKKKEDEK"
     gene            complement(7491..>7893)
                     /locus_tag="VQU30_001999"
     CDS             complement(7491..>7893)
                     /locus_tag="VQU30_001999"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001021424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="MucBP domain-containing protein"
                     /protein_id="HET2448040.1"
                     /translation="FKEADTNSASLTGNIVSEGRTVTLVYRESEAPTTATVTANYYKE
                     GSQEKLAESVIKADLAIGSEYTTESKTIEGKTTTEDKEDRVITRKTTYTLVATPANAY
                     QKTVQQLTITTVRMLRKQWFPKQQPLLRRRL"
BASE COUNT         2299 a         1646 c         1489 g         2459 t
ORIGIN      
        1 aaagctaata gcttatttga aattttctcc tctctgttgg atagtcccgt ctatctatgt
       61 tataatgaaa gaaggattta aaatcggaaa aggagtattt atgctaaaat taggtgtcat
      121 cggaactggc gctatcagcc atcatttcat agaagcagcc cataccagtg gagaatacca
      181 actggtcgca atctattcta gaaaactaga aactgcagca acctttgctt ctcgctatca
      241 gaatatccaa ctattcgatc aattagaagt cttcttcaaa tcttcttttg atttagtcta
      301 tatcgccagt ccaaactcct tacattttgc tcaggcaaaa gctgccttgt ctgctggtaa
      361 acatgttatt cttgaaaagc cagctgtcac tcaaccacaa gaatggtttg atttgattca
      421 aacagctgaa aaaaataact gttttatctt tgaagcagct cgtaattatc acgagaaagc
      481 ctttactact atcaaaaact ttttagcaga taagcaagtg ttaggagcag atttcaacta
      541 tgccaaatac tcttccaaga tgcctgactt attggctgga caaacaccaa atgtcttttc
      601 agaccgtttt gctggtggag ccctcatgga tttggggatt tatcccctct atgctgctgt
      661 tcgtcttttt gaaaaagcta atgacgcgac ttaccatgct caacagcttg acaatagcat
      721 tgacctaaat ggagatggta tcctcttcta cccagactat caagttcaca tcaaggctgg
      781 aaaaaacatc acttccaatc ttccttgcga gatttataca acagatggaa ccttgactct
      841 caacacgatt gagcatattc gctcagctat ttttaccgac caccaaggaa atcaagtcca
      901 gcttcctatc caacaggctc ctcatacgat gactgaggaa gtcgctgcat ttgcacacat
      961 gatccagcaa ccagatctga atctctacca aacttggctg tatgatgcag gctctgttca
     1021 tgagctacta tataccatgc gccagactgc tggcgttaga tttgaggcag aaaaatgaaa
     1081 accaaactac cgactgaatg gcaagaactg agtgaccaac tcggtttcca agaattcacc
     1141 cccattcaaa ctcaactatt tgagctcctt cttgctggag aaaacctcct aggagtgagc
     1201 caaaccggaa ctggtaagac cctagcgtat ctcctaccaa gtcttctcag actacaaaag
     1261 aaaaaagccc aacaactctt gattctagca ccaaacacgg aacttgctgg acagattttt
     1321 gatgtatgta aaacgtgggc agaagctatc ggattgactg ctcaactctt cctttcaggt
     1381 tcaagtcaga aacgacaaat tgaacgtctt aaaaaggggc cagaaattct gattggaact
     1441 cctggccgta tctttgaact cattaaactt aaaaaaatca agatgatgaa tgtggaaacc
     1501 atcatcctgg atgaatttga ccaattacta gatgattctc agattcactt tgtagagaaa
     1561 atcactcact acgcacctcg tgaccaccaa ctggtctaca tgagtgccac gaccaagttt
     1621 gaccaagaaa agattgtgcc gaatacacgc actattgatc tctctgatca aaaattggac
     1681 aatatccagc atttctacat gcaggtagac caacgtcatc gagtggatat gctacgaaaa
     1741 ctggctcatg tagaggattt ccgtggtcta gtcttcttca atagcctgtc agaccttggg
     1801 aatgccgagg aaaaactaca gtatcgtgat atattggctg tttccctcgc tagtgatgtt
     1861 aatgttaaat ttagaaaaat catcttagaa aagtttaaag ataaccaact aaccctgctt
     1921 cttgcaactg accttttggc tcgtggaatt gatatcgata gcctagaatg tgtcgtaaac
     1981 tttgatattc ctagagatag cgaaacctac acacaccgtg ctggccgtac tggtcgtatg
     2041 ggcaaggaag gttatgttat cactctcgtc actcatccag aagaaatcaa aaaacttaaa
     2101 aagtttgcaa gtatccgaga aattgtccta aaaaaccaag aactctatat caaataaagc
     2161 cccattgctc tatacacatc cagtgtatgg agctttttta taagcaattc aattttatac
     2221 tcatctgctt tcaaaaagca ttctagtcca tctccgatta acgatggact ttatcacctc
     2281 cttctccaat ccttgtatga catcttgaag ttgattcatg acatcttcca aaattcgaaa
     2341 ggctttattc ttaaatccac gtttacgaat ctctttccac acttgttcaa tggggttcat
     2401 ctctggtgtg tatggaggaa taaatgcaaa accaatatta gtcggaatct ttaagatact
     2461 tgatttatgc catatagcat tgtccataac gagtaaaaaa taatcatctg gataagcttg
     2521 tgaaagcttt tctaaaaagg cgttcatcca ctcagtatta catctaccag ctattaagaa
     2581 aaatgattcg cctgtatggg catcaacagc tccataacaa tagcgaaatt ctcgtatata
     2641 gtgactatgg atatgtggac ctactcctat tggagcccaa caagatccca gtttactgat
     2701 tctaccgaaa ccagcctcat cttggtacat caagcgaacc ttacgaaaac gtctactata
     2761 tttaaaacgc tttcttgtct tcttgaattg agattttatt tttagacgcg acaatggttt
     2821 gagcgtctgc tttcttagga tgttctggac gtggcataat atttcgccaa ccatggcgct
     2881 tcaacagttg atagaaggca tcacgtgtgt aggaacgacc taactccttt ttataagcct
     2941 gaaataaggc atcaattgta acaaattctc ctgcctctgc agccttcaaa tggcgggcaa
     3001 gaaagacttt ctcttcctca actgtcatat atgcatggtt acgaccacca cgtgtttctt
     3061 gaaggagaga gtcgagtccg aactcctcat atttttttac atttcgccaa atcattgttt
     3121 gattacagtc taaaagttct ataatctctt tataagattt gcccatatca gacgaaatag
     3181 aacgatttga agacgtttat gatatttagc tgtacgagag tcttttaaaa gtgttttgat
     3241 ggtttggatt tcttctttaa ttgatttcat attactattg tataatgctt tttgatttta
     3301 gtctagtatt atactcttcg aaaatctctt caaaccgcgt cagcttcgcc ttgtcgtata
     3361 gatgttactg acttcgtcag ttctatctac aacctaaaaa cagtgttttg agcagtctgt
     3421 agctaacttt ctatagtaaa atgaaataag aacaagacaa atcgatcagg acagtcaaat
     3481 cgatttctaa caatgtttta gaagtaaatg tgtactattc tagtttcaat atattatagt
     3541 ttgctctttg attttcattg agtattagtt caatatctaa aaaaagaacc ttgccaagca
     3601 agattctttt agtgtctgac ttaaataatt gttcttctgg gaactaaatc gaattaagct
     3661 tcgatttctg taaccatacc tgaaccaaca gtacgtccac cctcacggat agagaatgta
     3721 gtaccttgtt ctacggcgat tgggtgaatc aactcaacgt cgattgtcac gttatcacca
     3781 ggcattacca tttcagtacc tgctggaagt tcgattgaac ctgtaacgtc agtagtacgg
     3841 aagtagaatt gtggacggta gttgttgaag aatggagtgt gacgtccacc ttcttcttta
     3901 gtaaggatgt agacttcacc tttgaattta gtgtgtgggt tgattgaacc tggtttagcg
     3961 ataacttgtc cacgttcgat ttcatcacgt tgaacaccac gaagaaggac acctacgtta
     4021 tctccagcaa gaccttcgtc aagttgttta cggaacattt caacaccagt aacaactgct
     4081 ttttgagttt cttctttgat accaacgatt tcgatttcgt cgttgacttt aacgatacca
     4141 cggtcgatac gtcctgaagc aactgtacca cgtccagtga ttgagaatac gtcctcgact
     4201 ggaagaagca atggtttgtc agtgtcacgt tctggttctg ggatatactc atcaactgtg
     4261 ttcatcaatt ccataacgat gtcttcgtat ttagagtcac cttcaagagc tttaagtgct
     4321 gaaccttgga taactggaag atcgtcacct gggaagtcgt attctgacaa taggtcacgg
     4381 atttccattt caaccaattc aagcaattct tcgtcgtcaa ccaagtcaac tttgttcatg
     4441 aagacgataa ggtgtttaac accaacctga cgtgaaagaa ggatgtgctc acgagtttgt
     4501 ggcattggtc cgtcagttga agctactaca aggatagctc cgtccatttg agcagcacca
     4561 gtgatcatgt ttttaacgta gtccgcgtgt cctggagcgt cgatgtgagc gtagtgacgt
     4621 ttttcagttt cgtactcaac gtgcgcagtg ttgatagtga taccgcgttc gcgttcttct
     4681 ggagcagcat cgatagacgc atagtcttta ggttggttaa ctgatgaagg caagcgacgt
     4741 gccaaaacag ttgtgatagc tgcagttagg gtagttttac cgtggtcaac gtgtccgata
     4801 gtaccaatgt taacgtgtgg tttactacga tcgtattttt cttttgccat ttgagtaaaa
     4861 gcctccaata aaatatattt tatagataga cagtaggcaa tacagtctaa ctttccttac
     4921 tattttatca aatttcagct aaattgcaag tgttttacaa cgtttttgtg aattattctt
     4981 ggtaaaaatt taactaatta atagaaagta ctaaatagac ttatccttca aggagttttc
     5041 agcattatcc atccactcac ttgctgaaaa tgtaaacagt ctctggttta tatagtaaaa
     5101 tgaaacaaga atagagcaaa tcgatcagga cagtcaaatc gatttctaac aatgttttag
     5161 aagtagatgt gtactattct agtttcaatc tactatacaa cctcaaaact gtgttttgaa
     5221 caacctgcgg ctagcttctt agtttgccct ttgattttca ttgagtataa aattgcagat
     5281 aaaacgataa caatcatagg actcagcaga gtcaatgtag gtcgaagaat agccccccta
     5341 atcgcttatt ttatagcaaa atgaaataga aactgaacat tttgttgagg aaggtaaatc
     5401 aattcctcac aatgtttgag aaagaaggga ggactattcc aacttcaacc cactataaag
     5461 cagacttaca agatagggaa cccatctccg ataatatata gtagaatgaa aactgcacaa
     5521 tttgattgga gaattcaaac caatttctaa caatgtttta gaaacaaggg tctattattt
     5581 caactgcaac ctactatagc ccattgaagc tggaatagcc cactgagact tctaaaccac
     5641 tgctggagag gagtttgttt agagtttctt tcatttccct aaaaaatcaa aaagagagaa
     5701 ccagtctgat cctctcttac ttatagatgg tgctcactca aatgttaaag gagctatttc
     5761 ttagagataa aggaatttga atacagctac tgccgcaatt gctgctgcga taggtgctac
     5821 tactggtacc caagaatacc accattttga atcgccttta tgctcaccaa gaactgattt
     5881 tggaaggaaa gcatgaagga gacgtggtcc caagtcacgg gctgggttca aggcaggtcc
     5941 tgtaggtcct ccaagtgatg ttaccaaagc cataacgagg aatccaagtg ccaagtgagc
     6001 cacagaaagt cctgaagcag tgtgtggagc cacctgtgct ttaatagcca agtcagaaaa
     6061 atcaactgtt tgtcctgctt ctattgcctt ttgtttcatg aattgaagca cttcagcacc
     6121 aaagaagttt ttagtcaaac caagagctgc aaagaacaaa acaaatgaac caacaaactc
     6181 attaatcaaa ccattgacag ttgctgcata gcgactttct tttgtaccat ggtcaatact
     6241 tgaaatagtt gagaaagttc ccaagatgtt atttggtttt tcagttttca agtagaatgg
     6301 acggtatgtt gccacaacta aggcttggcc aaagatagcc cccaagactt gcgcgataat
     6361 gtaaggtacc acttgtgccc aagggaaaag accgctaact gcaagcccta gagtgaaagc
     6421 agggttgatg tgattcccag atacgttacc aaacatcaag gctgggatca taacccccat
     6481 accataacca acagcgatga cgatccagcc actttggtga cctttcgtac ctttaagttc
     6541 aacgttggca actgcaccat tcccaagaat gatcaaaatg gcagttccca aaaattcagt
     6601 ggcatacttc agtgcccatg tgaaatccat ttgctagatt ctccttaaaa ttttttagat
     6661 attccttatt ttatcaattt ttaccctatt tagcaactga tttctggaaa tatttttaaa
     6721 aaaataggat tcatagtttc ccagttcaac gtacttgtaa gcgtttttat tcttcacgaa
     6781 agacctcatt ctcaaaacca ggaaaaagcc cacatctgtg atcttttcct ggttcctaga
     6841 ttctaaaatc tattattttt catcttcttt tttcttgaag aatcctaatc ctagaccagc
     6901 taacaaggtc atgataccag cactagccaa ggtagcatta gcttctgtac ctgtgtttgg
     6961 caattcctct ctcttacctg tctcataagt cggaacttct gggtctggat tcactggagt
     7021 ttcagctttt ggagtacctg gttctggagt tggtttatct ggtgttggag tctcttgatt
     7081 tggtagttct gggtttggtg tcggaacact tggatgctct ggatttggtt gtgggattgg
     7141 tttttctgga gtcggttcac ctggagtacc tggttcctga ggacttggaa tttctggttt
     7201 ttctggagtt ggtttatctg gtgttgataa acggtcatac cttaccgtta tttctttatc
     7261 actagagtct gacgtaactt cttgtgattc aactgttgga atatctggat ctttgtactt
     7321 gtcaatctta ccagatataa cctcgtccca gtttcctgtt gtccattcac cgtaggttac
     7381 aactcccgtg accttgttct cagtttttgt acggcttaag gttacaggtt gaacaacatc
     7441 ttcttttaca ttttggttcg taactttatc aacgtaatga atgatacgcg ttatagtctt
     7501 cgtctcagta gaggttgctg ttttgggaac cactgtttcc tcaacattct cacggtagta
     7561 atagtcaact gttgcaccgt cttctggtac gcatttgcag gagttgctac caaggtgtat
     7621 gttgttttcc ttgtgataac tcggtcttct ttgtcctcag ttgttgtttt cccttcaata
     7681 gtttttgatt ctgtggtata ctcagaacct atcgctaaat cagcttttat aacagactct
     7741 gccaacttct cttggctacc ttctttatag taattggctg ttactgtagc agtggttggc
     7801 gcttcgcttt ctctataaac taaggtcact gttctacctt cgcttacaat attcccagtt
     7861 aaacttgcag aatttgtatc tgcttcttta aaa
//
LOCUS       DAVBBO010000077         7220 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ST1
            SAMEA2066453-rid20184263.denovo.077, whole genome shotgun sequence.
ACCESSION   DAVBBO010000077 DAVBBO010000000
VERSION     DAVBBO010000077.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2066453
            Sequence Read Archive: ERR351777
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 7220)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7220)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980402.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980402.1
            Genome Coverage       :: 176x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:17:33
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,141
            CDSs (total)                      :: 2,104
            Genes (coding)                    :: 1,953
            CDSs (with protein)               :: 1,953
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 16S)
            partial rRNAs                     :: 1 (23S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 151
            CDSs (without protein)            :: 151
            Pseudo Genes (ambiguous residues) :: 0 of 151
            Pseudo Genes (frameshifted)       :: 73 of 151
            Pseudo Genes (incomplete)         :: 76 of 151
            Pseudo Genes (internal stop)      :: 40 of 151
            Pseudo Genes (multiple problems)  :: 32 of 151
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7220
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2066453-rid20184263.denovo.077"
                     /strain="ST1"
                     /db_xref="taxon:1313"
     gene            231..645
                     /locus_tag="VQU30_002000"
                     /pseudo
     CDS             231..645
                     /locus_tag="VQU30_002000"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000720030.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(684..1127)
                     /locus_tag="VQU30_002001"
     CDS             complement(684..1127)
                     /locus_tag="VQU30_002001"
                     /EC_number="3.1.1.96"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-tyrosyl-tRNA(Tyr) deacylase"
                     /protein_id="HET2448041.1"
                     /translation="MKIIIQRVKKAQVSIEGQIQGKINQGLLLLVGVGPEDQEEDLDY
                     AVRKLVNMRIFSDAEGKMNLSVKDIEGEILSISQFTLFADTKKGNRPAFTGAAKPDMA
                     SDFYDAFNQKLAQEVPVQTGIFGADMQVELVNNGPVTIILDTKKR"
     gene            complement(1157..3379)
                     /locus_tag="VQU30_002002"
     CDS             complement(1157..3379)
                     /locus_tag="VQU30_002002"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019316080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional (p)ppGpp
                     synthetase/guanosine-3',5'-bis(diphosphate)
                     3'-pyrophosphohydrolase"
                     /protein_id="HET2448042.1"
                     /translation="MPKEVNLTGEEVVALTKEYLTEEDVHFVHKALVYAVECHSGQYR
                     KSGEPYIIHPIQVAGILAKLKLDAVTVACGFLHDVVEDTDATLDDLEREFGPDVRMIV
                     DGVTKLGKVEYKSIEEQLAENHRKMLMAMSEDIRVILVKLSDRLHNMRTLKHLRKDKQ
                     ERISKETMEIYAPLAHRLGISSVKWELEDLSFRYLNPTEFYKITHMMKEKRREREALV
                     DEVVTKLEEYTTERHLKGKIYGRPKHIYSIFRKMQDKRKRFEEIYDLIAIRCILDTQS
                     DVYAMLGYVHEFWKPMPGRFKDYIANRKANGYQSIHTTVYGPKGPIEFQIRTKEMHEV
                     AEYGVAAHWAYKKGIKGQVNSKESAIGMNWIKEMMELQDQADDAKEFVDSVKENYLAE
                     EIYVFTPDGAVRSLPKDSGPIDFAYEIHTKVGEKATGAKVNGRMVPLTTKLKTGDQVE
                     IIANPNSFGPSRDWLNMVKTSKARNKIRQFFKNQDKELSVNKGREMLMAQFQENGYVA
                     NKFMDKRHMDQVLQKTSYKTEDSLFAAIGFGEIGAITVFNRLTEKERREEERAKAKAE
                     AEELVKGGEVKVENKETLKVKHEGGVVIEGASGLLVRIAKCCNPVPGDDIVGYITKGR
                     GVAIHRVDCMNLRAQENYEQRLLDVEWEDQYSSSNKEYMAHIDIYGLNRTGLLNDVLQ
                     VLSNTTKNISTVNAQPTKDMKFANIHVSFGIANLSTLTTVVDKIKSVPEVYSVKRTNG
                     "
     gene            3790..4032
                     /locus_tag="VQU30_002003"
     CDS             3790..4032
                     /locus_tag="VQU30_002003"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001808964.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2448043.1"
                     /translation="MTRFEEIFEEYKNPQDTFFYPLVYKENTYEKTAISIFALLMLGV
                     CCLFLFSQQSYKKLVQYYANDQNLPSRITYSEYSDK"
     gene            4372..5001
                     /locus_tag="VQU30_002004"
     CDS             4372..5001
                     /locus_tag="VQU30_002004"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000690864.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HET2448044.1"
                     /translation="MKIHKTVNPVAYENTYYLEGEKHLIVVDPGSHWEAIRQTIEKIN
                     KPICAILLTHAHYDHIMSLDLVRETFGNPPVYIAESEASWLYTPVDNLSGLPRHDDMA
                     DVVTKPAEHTFVFHEEYQLEEFRFKVLPTPGHSIGGVSLVFPDAHLVLTGDALFRETI
                     GRTDLPTGSMEQLLHSIQTQLFTLPNYDVYPGHGPATTIAHEKAFNPFF"
     gene            complement(5124..7016)
                     /gene="pepO"
                     /locus_tag="VQU30_002005"
     CDS             complement(5124..7016)
                     /gene="pepO"
                     /locus_tag="VQU30_002005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000199272.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endopeptidase PepO"
                     /protein_id="HET2448045.1"
                     /translation="MTRYQDDFYDAINGEWQQTAEIPADKSQTGGFVDLDQEIEDLML
                     ATTDKWLAGEEVPEDAILENFVKYHRLVRDFDKREADGITPVLPLLKEFQELETFADF
                     TAKLAEFELAGKPNFLPFGVSPDFMDARINVLWASAPSTILPDTTYYAEEHPQREELL
                     TLWKESSANLLKAYDFSDEEIEDLLEKRLELDRRVAAVVLSNEESSEYAKLYHPYSYE
                     DFKKFAPALPLDDFFKAVIGQLPDKVIVDEERFWQAAEQFYSEEAWSLLKATLILSVV
                     NLSTSYLTEDIRVLSGAYSRALSGVPEAKDKVKAAYHLAQEPFKQALGLWYAREKFSP
                     EAKADVEKKVATMIDVYKERLLKNDWLTPETCKQAIVKLNVIKPYIGYPEELPARYKD
                     KVVNETASLFENALAFARVEIKHSWSKWNQPVDYKEWGMPAHMVNAYYNPQKNLIVFP
                     AAILQAPFYDLHQSSSANYGGIGAVIAHEISHAFDTNGASFDENGSLKDWWTESDYAA
                     FKEKTQKVIDQFDGQDSYGATINGKLTVSENVADLGGIAAALEAAKREADFSAEEFFY
                     NFGRIWRMKGRPEFMKLLASVDVHAPAKLRVNVQVPNFDDFFTTYDVKEGDGMWRSPE
                     ERVIIW"
BASE COUNT         1985 a         1681 c         1378 g         2176 t
ORIGIN      
        1 ttatcatttt atgacaaaca tactatcgtt aaatgctgat ttaatcgaaa ttttgagtta
       61 taaactcctc agtttcgaac tcaaaattag ccgtgcagga taggataccc ttcataaact
      121 tatataacta ctttaatacc ttaaaaagct aataaaataa ggaatatcta agcaatatac
      181 attctaaaat acctgtacgg gagtgtctct aaagaaaagg aggttttagc atgaaaaaaa
      241 tcatcttcat caaaaccatt caactccttg tcattgatgg aatcatgctg gcatttttga
      301 catttaaaag gggggcttac ttgggactgg attttgattt atagtggttg gctcattttc
      361 tttcatcctg tgctattgac ctatctttca aaccaacttt gtgaccactt tagtcaactc
      421 tattcccaga ttagaccgag attctggcgt tttgctttac aaattctcct atgggatagc
      481 ctgatgattc tctccttggt gtctttaagt gatattccac ttttccttca gggaactctc
      541 ctcatcctag gacatctcat cccttcctat cgcatctgcc aaagcctgaa aagagacttc
      601 ccccaagcat atcaagaacc gatttctttt tggagtattt tatgatcgat gagaaagacc
      661 aagccgactg ggcttggtct ttcttatctc tttttagtat ctaggataat ggtaacaggt
      721 ccgttattaa ccagctcaac ctgcatatct gctccaaaga tacctgtctg aacgggcact
      781 tcttgcgcta atttttgatt gaaagcatca tagaagtctg atgccatatc aggtttagct
      841 gcccctgtaa aggctggacg attgcctttc ttagtatccg caaagagggt aaactgagaa
      901 atagagagga tttctccttc aatatctttg acagacaggt tcatcttgcc ttctgcgtct
      961 gaaaaaatcc gcatattgac cagttttctc acagcatagt ccaaatcttc ctcttggtcc
     1021 tctggtccaa caccaaccag caataaaagt ccctgattga tttttccctg aatctggcct
     1081 tctatactca cttgggcttt tttaacccgt tggataatga ttttcataat agcctttcta
     1141 gtaagagcta ggacaactag ccgttggtcc gtttgacaga gtaaacttct ggcacactct
     1201 taattttatc gacaaccgtg gtcagtgtag agaggttggc aataccgaag gacacatgga
     1261 tattagcaaa cttcatatcc ttggttggtt gggcattgac cgttgaaata ttcttggttg
     1321 tatttgaaag aacttgcagt acatcgttca acagtcctgt acggttgaga ccgtagatat
     1381 cgatatgggc catatactcc ttatttgagc tagagtactg gtcttcccat tccacatcaa
     1441 ggagacgttg ctcgtagttt tcttgggcac gcaggttcat acagtccaca cggtgaatag
     1501 ccacaccacg acccttggta atgtagccaa caatatcgtc accaggcacg gggttacaac
     1561 acttagcaat ccgcactagg agaccagaag caccttcaat aaccactccc ccctcatgct
     1621 tgaccttgag agtttcttta ttttcaacct tgacctcgcc acctttgaca agctcctctg
     1681 cctcagcctt ggccttggca cgctcttcct cacggcgttc cttttcagtc agacggttaa
     1741 agacggtaat cgcaccgatt tccccaaaac caatggccgc aaagagggag tcttctgtct
     1801 tgtaactggt cttttgcaga acttgatcca tgtggcgctt gtccataaat ttatttgcca
     1861 catagccatt ttcttggaac tgagccatca gcatctcacg acccttgttg acagacaatt
     1921 ccttatcttg gtttttaaag aactggcgaa tcttattgcg cgccttgcta gtcttgacca
     1981 tattgagcca gtcacggcta ggtccaaagg agttcgggtt ggcgataatt tcaacctgat
     2041 cccctgtctt taacttggtt gtcagtggaa ccatgcggcc attgaccttg gcaccagttg
     2101 ctttttcacc gaccttggta tggatttcgt aggcaaaatc aatcggtcct gaatctttgg
     2161 gaagagaacg gacagctcca tctggggtaa aaacgtaaat ctcctcagcc agatagtttt
     2221 ccttaacaga gtccacaaat tccttagcat catcagcctg gtcttggagc tccatcatct
     2281 ccttgatcca gttcattcca atagctgatt ccttgctgtt aacttgcccc tttatacctt
     2341 tcttataagc ccagtgagcc gcaaccccgt actcagccac ctcgtgcatt tccttggttc
     2401 gaatctggaa ttcaatcggc ccttttggtc cataaacagt cgtatggata gactgataac
     2461 cattagcctt gcggttggca atatagtctt tgaagcgacc tggcatcggt ttccaaaatt
     2521 catgcacgta accaagcatg gcataaacat cactttgggt atctaaaata caacgaatag
     2581 caatcagatc atagatttcc tcaaaccgtt ttctcttgtc ctgcattttg cggaaaattg
     2641 agtaaatatg cttgggacga ccataaatct tccctttcaa gtgacgttct gtcgtatact
     2701 cctctaattt tgtgactacc tcatccacca aggcctcacg ctccctgcgc ttttccttca
     2761 tcatatgggt aatcttgtaa aactccgttg gattgagata acggaaagac aagtcttcta
     2821 attcccattt gacactggaa atccccaaac gatgggcaag cggggcatag atttccatgg
     2881 tttctttgga aatacgctcc tgcttgtctt ttcgaagatg tttcagggtc cgcatattgt
     2941 gcaagcggtc agacagtttg accaaaataa cgcggatgtc ctcagacatg gccatgagca
     3001 tcttgcgatg attttccgct aattgctcct cgatcgattt gtactcgacc ttgccaagct
     3061 tggtaactcc gtcaacaatc atccgcacat caggaccaaa ctctctttcc aaatcgtcca
     3121 aagtcgcatc tgtatcttcc accacatcat gcaagaatcc acaagctact gttacagcat
     3181 ccagctttag cttagctaaa atacctgcca cttggatagg gtgaatgata taaggctcgc
     3241 ctgatttgcg atattgacca ctgtggcatt caacagcata gaccaaggcc ttatggacaa
     3301 aatgaacatc ctcttccgtt aaatattctt tggttaaagc gacaacttct tcgcctgtta
     3361 aattcacttc tttcggcatc tctactctcc aattcttcct accattttat cactttttta
     3421 agaatatgaa aactagattg gaacagaata agaaaaaaat aattcaaaat tgcttgataa
     3481 ttctgaatta ttggcccata atatactacg aagttagatt ttaaacttag gtgatagaag
     3541 gagagataga agaacggaaa ccatattgta acccaaagac tttctgattt ccccaattcc
     3601 attgaagata cgaaagataa acggtggaac tcgtatcaca tacactggta ccttgactgg
     3661 attttggaat taatactcaa tgaaaatcaa agagcaaact aggaaactag ccacaggttg
     3721 ctcaaagcac tgctttgagg ttgtagataa gactgacaaa gtcagtcaca tatatacggc
     3781 aaggcgacgt tgacgcggtt tgaagagatt tttgaagagt ataaaaatcc tcaagatact
     3841 ttcttctatc ctttagttta taaggagaat acctatgaaa aaactgctat ttctatcttt
     3901 gctctcctaa tgttaggagt ttgctgcctg ttcctattca gccagcaaag ctataaaaaa
     3961 ctcgttcaat actatgctaa cgaccagaac ctgcccagta ggataactta tagtgaatat
     4021 agcgacaaat gagaagccaa ctacggtagc actctaaaca tcacgtctat caaacaagct
     4081 aatgacggag tttatgcaac ctatgaaggg caattgacac ctttccaata ttgataaatt
     4141 gataaccagc ctgtcttcat ctagtcatgc tggtttttaa gttcatttta aatccttacc
     4201 tattctccct aactgtgcta tacttaattt atactcaatg aaaatcaaag agcaaactag
     4261 aaagctagcc gcaggctgtt caaagcactg ctttgaggtt gcagataaag ttgacgcggt
     4321 ttgaagagat tttcgaagag tattagtaca ttctttgaga ttggagttag tatgaaaatc
     4381 cataaaaccg tgaatcctgt tgcctatgaa aatacctatt atctagaagg cgaaaagcac
     4441 ctcatcgtcg tcgatcctgg tagtcattgg gaagccattc gtcagacaat cgagaagatc
     4501 aacaaaccga tctgtgctat tctcttgacc cacgcccatt atgaccatat catgagtctg
     4561 gacttggttc gcgagacgtt tggcaatcct cctgtctata tcgcagagag cgaagccagc
     4621 tggctctaca ctcctgtcga taatctctcc ggtctccctc gccacgatga tatggcagat
     4681 gtggtcacaa aacctgcaga acacaccttt gtctttcacg aagaatacca actagaggaa
     4741 tttcgtttta aggttctacc gaccccaggg cactctatcg gtggtgtttc cctagtcttt
     4801 cctgatgctc acctagtctt gacgggagat gctctattcc gcgaaactat cggacggacc
     4861 gaccttccga ctggtagcat ggagcaactc cttcatagta tccagaccca actcttcacc
     4921 ctaccaaact acgatgtcta tccaggacat ggtccagcta ctactatcgc tcacgaaaag
     4981 gccttcaatc cctttttcta gcaagatgat gacaatcgaa atttaagtaa actatccagc
     5041 aaatctttct attacaaaag gcatcctatc aaggttttca cacgtgattg gatgcctttt
     5101 ttctgatgac tagatttttt gtattaccaa ataatcacgc gctcctctgg tgaacgccac
     5161 attccgtctc cttctttgac atcataggtt gtaaagaaat cgtcgaagtt tggtacttgc
     5221 acattgacac ggagtttggc tggtgcgtgc acatcgacgc tagccaaaag tttcataaat
     5281 tctggtcgac ctttcatgcg ccagatgcga ccgaagttgt agaagaactc ttctgctgag
     5341 aagtctgctt ctctcttagc tgcttcaagc gctgctgcga ttcctcccaa gtcagccacg
     5401 ttttctgata cagtcaattt accgttaatg gttgctccat aagaatcctg tccatcaaat
     5461 tggtcaatga ctttttgtgt tttctccttg aaggcagcat agtcgctctc tgtccaccaa
     5521 tccttgaggc taccattttc gtcaaaggaa gccccgttag tatcaaaggc gtgggaaatt
     5581 tcatgggcaa tcactgcccc aataccaccg tagttagcag aagatgactg atgcaagtca
     5641 tagaaaggcg cctgtaaaat ggccgctgga aagacaatca ggttcttctg aggattgtag
     5701 taggcattga ccatatgagc aggcatgccc cattccttat agtctacagg ctggttccac
     5761 ttactccaac tgtgcttgat ttccacacgc gcaaaggcta gagcattctc aaaaagactg
     5821 gcagtttcat tcactacctt atccttgtaa cgtgcaggca attcttctgg atagccaata
     5881 taaggtttga tcacattgag cttcacgata gcctgtttac aggtttctgg agtgagccag
     5941 tcattcttaa gcagacgctc cttatagaca tcaatcatgg ttgccacttt tttctccaca
     6001 tccgccttgg cttctggaga gaacttctca cgggcgtacc aaagccccag ggcttgcttg
     6061 aaaggttcct gtgctagatg ataagctgct ttgaccttat cttttgcctc tggaactcca
     6121 gaaagggcac ggctgtaggc accagacaaa acacggatat cctctgttaa atagctggtt
     6181 gaaagattga caacactcaa aatcaaggtt gctttaagga gagaccaggc ttcctcactg
     6241 taaaattgct ctgctgcttg ccagaaacgt tcctcgtcta caataacctt gtctggtaat
     6301 tgcccaataa ctgctttgaa gaagtcatcc aaaggtaggg caggcgcgaa tttcttgaaa
     6361 tcttcgtaag aatatggatg atagagttta gcatattctg aactttcttc attagagagc
     6421 accactgccg caactcggcg gtccaattca agtctttttt ctagcaagtc ttcaatttct
     6481 tcatcagaga aatcataagc cttgaggaga tttgcgctgc tttctttcca aagagtcaag
     6541 agctcttcgc gctgaggatg ttcttctgca tagtaggtcg tatctggcaa gattgtgctt
     6601 ggagcgctag cccatagaac attgattcta gcatccataa agtctggcga tacaccaaaa
     6661 ggaaggaagt ttggttttcc tgcaagctca aactctgcta gtttagctgt aaaatccgca
     6721 aaagtttcca attcttggaa ttctttaagg agtggtaaga caggtgtgat accgtcagct
     6781 tctctcttgt caaaatcacg aactaggcgg tggtatttga caaagttttc caagatagca
     6841 tcctcaggca cttcttcacc tgctaaccac ttgtctgttg tcgccagcat caggtcttca
     6901 atttcctggt ctaaatcaac aaaacctcct gtttgagact tatctgctgg gatttcagct
     6961 gtctgttgcc attctccatt gatagcatca taaaaatcat cttgataacg tgtcatcttg
     7021 ttctcgcttt catttgtatt tgcatttatc ttaacaaaaa tcactaggga atgcaattaa
     7081 taaccattta actattattt tttagctatt ataaaaaacc tttccatgat aaaacgcata
     7141 attccaagtt ttttacactt gatactatgc gttttataat ttagaaattt atcctgaaag
     7201 ttatctttag aatctatttt
//
LOCUS       DAVBBO010000078         7162 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ST1
            SAMEA2066453-rid20184263.denovo.078, whole genome shotgun sequence.
ACCESSION   DAVBBO010000078 DAVBBO010000000
VERSION     DAVBBO010000078.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2066453
            Sequence Read Archive: ERR351777
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 7162)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7162)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980402.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980402.1
            Genome Coverage       :: 176x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:17:33
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,141
            CDSs (total)                      :: 2,104
            Genes (coding)                    :: 1,953
            CDSs (with protein)               :: 1,953
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 16S)
            partial rRNAs                     :: 1 (23S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 151
            CDSs (without protein)            :: 151
            Pseudo Genes (ambiguous residues) :: 0 of 151
            Pseudo Genes (frameshifted)       :: 73 of 151
            Pseudo Genes (incomplete)         :: 76 of 151
            Pseudo Genes (internal stop)      :: 40 of 151
            Pseudo Genes (multiple problems)  :: 32 of 151
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7162
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2066453-rid20184263.denovo.078"
                     /strain="ST1"
                     /db_xref="taxon:1313"
     gene            complement(741..1001)
                     /locus_tag="VQU30_002006"
     CDS             complement(741..1001)
                     /locus_tag="VQU30_002006"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2448046.1"
                     /translation="MRERSATGAQGLSKSIKKHLNDLTRLTASLLGDEKLSAITSSSA
                     VKADIHRFVIELEPVKSTILQNDDISLDQNEIFEILKNFLDG"
     gene            complement(1060..1611)
                     /locus_tag="VQU30_002007"
     CDS             complement(1060..1611)
                     /locus_tag="VQU30_002007"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001111259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2448047.1"
                     /translation="MPANTKVIFQEMFADFQNYYVLIGGTATSIVLDSQGFKSRTTKD
                     YDMVIIYEVKNKEFYTTLNHFLELGEYQGSQKDEKAQLFRFTTTNPEFPSMIELFSIL
                     PEYPLKKDGREIPLHFDQDASLSALLLDEDYYNILVHEKETIQGYSVLSNCGLYSSKI
                     SSNHVSFHLQPQNSVLSSLQLAS"
     gene            complement(1601..1798)
                     /locus_tag="VQU30_002008"
     CDS             complement(1601..1798)
                     /locus_tag="VQU30_002008"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000890145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2448048.1"
                     /translation="MLEIWKYRPFVSEFWNDFKNNHDKQFVDPISLYLTLKDDDDPRI
                     EEESEALENMILQYLGEDDAS"
     gene            complement(1802..2386)
                     /locus_tag="VQU30_002009"
     CDS             complement(1802..2386)
                     /locus_tag="VQU30_002009"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001101186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2448049.1"
                     /translation="MNVKKIMSIFQSFYVDVSIEELTLTLPISFVKRFEYTQMTFHKE
                     SFLLIKEKRRGSLSSFVTQARTMGEKANMDVVLVFSKLSDSEKKQLLQARVPFVDFKG
                     NLFFPPLGLVLNANDTEIPKELTPSEQLTWIAFLLPDGDIKQIKSVSNLLYGGAYALS
                     HSTFLAETDENTSYVIWQRKFNQLSLPLSQHVLK"
     gene            complement(2794..3219)
                     /locus_tag="VQU30_002010"
     CDS             complement(2794..3219)
                     /locus_tag="VQU30_002010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000204059.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2448050.1"
                     /translation="MTSRVFIDADCISAFLWVGTEHLLEKLYSGKIVIPQEVYDEINI
                     PTIPHLKSRIDQLVTKGSAEIVSIDIGTEEYALYRDLTRNYDSNKIIGKGEATSIFLA
                     KKHNGILGSNNLRDVKPYVEEFSLEHMTTGDILIEAFKA"
     gene            complement(3212..3706)
                     /locus_tag="VQU30_002011"
     CDS             complement(3212..3706)
                     /locus_tag="VQU30_002011"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004236771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2448051.1"
                     /translation="MKKSSVSLILIGEGDETERKADQFASYFLIFPSSLYRMVEEIRE
                     NANRTHLEVEDIIKLGQFYGISHKAMLYRLRNDGYLDAEEIKNMDISVIETASRLGYD
                     TSLYRPLSESKKEMVLGHYIKSTEQLLENNRISQGKYEELLLDAFRYDIVYGLDEEGE
                     LSFD"
     gene            complement(3752..3958)
                     /locus_tag="VQU30_002012"
     CDS             complement(3752..3958)
                     /locus_tag="VQU30_002012"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000366086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2448052.1"
                     /translation="MDLSNKASNLRKKLGADGESPIDIFKLVQKIENLTLVFYGLGKN
                     ISGVCYKGTQFSLIAVNSDMPLGR"
     gene            complement(3945..4106)
                     /locus_tag="VQU30_002013"
     CDS             complement(3945..4106)
                     /locus_tag="VQU30_002013"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000289348.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HET2448053.1"
                     /translation="MNMINVCDVGKRIKELRISSNLTQDKIAEYLSLNQSMIAKMEKG
                     ERNITNGFK"
     gene            complement(4471..5427)
                     /gene="lytA"
                     /locus_tag="VQU30_002014"
     CDS             complement(4471..5427)
                     /gene="lytA"
                     /locus_tag="VQU30_002014"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000405235.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase LytA"
                     /protein_id="HET2448054.1"
                     /translation="MEINVSKLRTDLPQVGVQPYRQVHAHSTGNPHSTVQNEADYHWR
                     KDPELGFFSHIVGNGCIMQVGPVDNGAWDVGGGWNAETYAAVELIESHSTKEEFMTDY
                     RLYIELLRNLADEAGLPKTLDTGSLAGIKTHEYCTNNQPNNHSDHVDPYPYLAKWGIS
                     REQFKHDIENGLTIETGWQKNDTGYWYVHSDGSYPKDKFEKINGTWYYFDSSGYMLAD
                     RWRKHTDGNWYWFDNSGEMATGWKKIADKWYYFNEEGAMKTGWVKYKDTWYYLDAKEG
                     AMVSNAFIQSADGTGWYYLKPDGTLADKPDFTVEPEGLITVK"
     gene            complement(5803..7155)
                     /locus_tag="VQU30_002015"
     CDS             complement(5803..7155)
                     /locus_tag="VQU30_002015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000364185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MATE family efflux transporter"
                     /protein_id="HET2448055.1"
                     /translation="MDLIHGPILPSLLSFTFPILLSNIFQQLYNTADVLIVGRFLGQE
                     SLAAVGATTAIFDLIVGFTLGVGNGMGIVIARYYGARNFTKIKEAVAATWILGALLSI
                     LVMLLGFLGLYHLLQYLDTPAEILPQSYQYISMIVTCVGVSFAYNLFAGLLRSIGDSL
                     AALGFLIFSALVNVVLDLYFITQLHLGVQSAGLATIISQGLSAVLCFYYIRKSVPELL
                     PQFKHFKWDKSLYADLLEQGLAMGLMSSIVSIGSVILQFSVNTFGAVIISAQTAARRI
                     MTFALLPMTAISASMTTFASQNLGAKRPDRIVQGLRIGSRLSISWAVFVCIFLFFASP
                     ALVSFLASSTDGYLIENGSLYLQISSAFYPILSLLLIYRNCLQGLGQKILPLVSSFIE
                     LIGKIVFVVLIIPWAGYKGVILCEPLIWVAMTVQLYFSLFRHPLIKEGKAILATKVQS
                     "
BASE COUNT         2298 a         1486 c         1132 g         2246 t
ORIGIN      
        1 tggtttcgca ggaagtctat tatatatgca cagacatatg aaatcttttt gagacagcag
       61 ttatgatata tttatccatt cacaacatct tctgtactaa tactacaata ttggtacatt
      121 ttgattacac aatcgtttca aaaaatatga tggaagcctg agtattttat agtaattccc
      181 ttcctatcaa ctagatcaac cagttgagtg ttgaatgttg aaacacccta gcctcagcaa
      241 aggactatga tcagcatttc ctagccaata ggacgctcca aatcacctat tctaagtcca
      301 tcactagctt ggtcagtaag atacagactg caaggcgaga ctgacgtggt tgatgagatt
      361 ttggaagagt attacaatca tagattcacc agtagacttg accgcagatt taactatagt
      421 agattgaaac tagaatagta catctctgct tctaaaacat tgttagaaat cgatttgact
      481 gtcctgatca atttgtcctg ttctcgtttc atttcactat actaaaaaac cacctgaaac
      541 aaatcaagtg actagaggat aaaaacaaag actaggcaaa aagttttgaa aagcaaaaaa
      601 cgcataatat caggtcttga aaaaccttga tactatacgt ttgattgtgg gaagattgac
      661 ttcattttct cctgaaattg aagttttttc tagtttccag atatagacga attcaatata
      721 gccatctcgc tacaattatt ttaaccatcg agaaaatttt tcagaatttc aaaaatttca
      781 ttttgatcca atgaaatgtc atcattttga agaatagttg acttcacagg ctctaattct
      841 atcacaaagc ggtgtatgtc tgcttttacc gcactacttg atgttatagc cgataacttt
      901 tcatctccta gcaaggaagc tgtcaaacgg gtaaggtcat tcaaatgctt tttaatggac
      961 ttacttaaac cttgagcacc tgtagcagag cgttccctca tatccagcca agctttagcc
     1021 ttaaaaataa ttaatactca atgaaaatca aagagcaaac taggaagcta gctgcaggct
     1081 gctcaaaaca ctgttttgag gttgtagatg gaagctgacg tggtttgaag agattttcga
     1141 agagtataaa ccacaattac tcaataccga atacccctga atggtttctt tttcatgcac
     1201 caatatatta taataatctt catccaataa taaggctgat aaactagcat cttggtcaaa
     1261 atgtaaggga atttctcgac cgtccttctt taatggatat tctggtaaga tactaaatag
     1321 ttcaatcata gaaggaaact caggattagt tgttgtaaat cgaaaaagct gcgctttctc
     1381 atctttctga cttccttgat actctcccaa ttctaaaaaa tgattcaagg tagtataaaa
     1441 ttccttattt tttacttcat aaatgatgac catatcataa tcttttgttg tgcgactttt
     1501 aaatccttgc gaatccaata cgatagaggt agcagttccc ccaatcagaa cataatagtt
     1561 ctgaaaatcc gcaaacattt cttgaaaaat aactttcgta ttagctggca tcatcttctc
     1621 ccagatactg taatatcata ttttctagtg cttcactctc ttcctctata cgtgggtcat
     1681 catcatcttt taaggtcaaa taaagagaaa tcggatctac aaattgttta tcatgattat
     1741 ttttaaaatc attccaaaac tcagatacaa aaggacgata tttccatatc tctagcatct
     1801 ttcattttaa aacatgctga gaaagtggca aggataactg attgaatttt ctctgccata
     1861 tgacatagct agtattttca tccgtttcag ctaaaaaagt tgaatgcgac aaagcataag
     1921 caccaccata tagaaggtta gaaacagatt ttatctgctt tatatcgcca tctggcaata
     1981 aaaaggcaat ccacgttaat tgttcgctag gtgttaattc cttagggatt tcagtatcat
     2041 tcgcattgag tactagtccc aatggaggga agaagaggtt tcccttaaag tctacaaacg
     2101 gaactctagc ttgaagtaat tgcttttttt cactgtctga taacttcgaa aacaccaaaa
     2161 caacatccat attggctttt tcacccatag tgcgagcctg agtaacaaat gaactcaaac
     2221 tcccccttct cttttcttta atcaataaaa atgattcctt atgaaaagtc atttgagtat
     2281 actcaaacct ttttacaaaa ctgattggta aagtcaaagt cagttcctca atactgacat
     2341 caacataaaa ggattgaaaa attgacatta tctttttgac attcatgttt tttccttatt
     2401 ctatcatttt tattatattt tatcattcgg tataataaaa tataagtttt ttgataaaat
     2461 aaccaaaaac tactcgctat cccctctcac attaccctac atatcgtttg acatgcgact
     2521 gatagttcag gaaaacttca aggagaactt ttctctcatc cactatgcag gacttactat
     2581 ttcacttcta ctcctatagg ctcaatttga cacttttctt tttcgaattg ctcatatgcc
     2641 tcctgaatag tgagttcgat ttatccaaat ttatttttgt ctattttgat gaatacttcc
     2701 acgaagatag tctgaaaatg aatttgcacc aattttcctt ctctttttaa gcatattatt
     2761 ccagatatga ttgccctctt gttcagtaat aaattacgct ttaaacgctt caatcagtat
     2821 atctcctgtt gtcatatgtt ctaaagaaaa ttcttctaca tatggtttaa catctcttag
     2881 gttattactt cctaatatcc cattatgctt tttcgctaag aaaatagaag tcgcttctcc
     2941 cttaccaata atcttgttac tatcataatt tcttgttaaa tctctatata atgcgtattc
     3001 ttcagttcca atgtctatgc tcacaatctc agctgaaccc ttagttacca actggtctat
     3061 cctagatttt aaatggggaa ttgtaggtat attgatttca tcatacacct cttgtggaat
     3121 aacaatttta cccgaataga gcttttctaa aagatgttca gtgccaaccc ataaaaatgc
     3181 tgaaatacaa tctgcatcaa taaatacacg actagtcaaa cgacaactcc ccctcttcat
     3241 ctagcccata tacaatatca tatctgaaag catctagtaa cagttcctca tacttccctt
     3301 gcgaaattct gttattttct aaaagttgtt cagtcgattt aatatagtgc cctaatacca
     3361 tttccttttt actttctgac aaaggacgat ataaacttgt atcatagcct aatcttgaag
     3421 ctgtctctat aacactaata tccatatttt taatttcttc tgcatcaagg tatccatcat
     3481 ttctcaatct atataacata gctttatgac tgataccata aaactgaccc aattttataa
     3541 tatcttctac ttcaagatga gttctattgg cattttctct gatttcctca accatcctat
     3601 acagtgaaga tgggaaaatt aaaaaataag aagcaaactg atccgctttt ctttcagttt
     3661 catctccttc accaatcaag ataagactga ctgaactctt cttcacctca tcataataaa
     3721 gatgatacag tccatgtgct aaagaaaatc tttaccttcc taatggcatg tctgaattga
     3781 ctgcaatgag actgaactga gttcctttat aacagactcc gctaatattc tttccgagtc
     3841 cataaaatac cagcgtcaaa ttttctatct tttgtaccaa tttaaaaata tctatcggcg
     3901 attcaccatc agctcccaac ttttttctaa gatttgaagc tttattactt aaatccattc
     3961 gtgatattcc tttcaccttt ttccattttg gcaatcatgc tttgattcaa agacaaatac
     4021 tcagcaatct tatcttgagt aagatttgaa gatattctaa gttcttttat tctttttcca
     4081 acatcacata catttatcat attcatacac ctctcataaa aagaatagca cattcttgtc
     4141 ataatttttt aaataaaaaa attatgacaa aacaaggaag caatttattg atgctactta
     4201 aaaatctaaa attgatgata ttaaacctat ttgatgagtt cctatcaaaa atcgtatctt
     4261 caacctcaaa acagtactta aagctatccg actcggttta cattgtcaaa tttagatttt
     4321 atttgagcat aactttctag tttgcttttt gatttttgtt taatatagta acaaaaattg
     4381 aaggaaatat ctccacaaga aaacgcatac tattaagctt tttcaagacc taataatatg
     4441 cgctgttctg atttgaaaga cattccatta ttattttact gtaatcaagc cttcaggctc
     4501 tactgtgaag tctggcttgt ctgccagtgt tccgtctggt ttgaggtagt accagcctgt
     4561 tccgtccgct gactggataa aggcatttga taccatggcg ccttctttag cgtctaagta
     4621 gtaccaagtg tccttgtact tgacccagcc tgtcttcatg gcaccttctt cgttgaaata
     4681 gtaccactta tcagcgattt tcttccagcc tgtagccatt tcgcctgagt tgtcgaacca
     4741 gtaccagttg ccgtctgtgt gcttcctcca gcggtctgca agcatatagc ctgaactgtc
     4801 aaagtagtac caagtgccat tgattttctc aaacttgtct tttggataag agccgtctga
     4861 atgtacgtac cagtagccag tgtcattctt ctgccagcct gtttcaatcg tcaagccgtt
     4921 ctcaatatca tgcttaaact gctcacggct aatgccccat ttagcaagat atggataagg
     4981 gtcaacgtgg tctgagtggt tgtttggttg gttattcgtg caatactcgt gcgttttaat
     5041 tccagctaaa ctccctgtat caagcgtttt cggcaaacct gcttcatctg ctagattgcg
     5101 taagagttcg atataaaggc ggtagtccgt catgaactct tctttggttg aatggctttc
     5161 aatcagttca accgctgcat aggtctcagc attccaaccg cccccaacgt cccaggcacc
     5221 attatcaaca ggtcctacct gcatgatgca accgttccca acaatgtgcg agaaaaaacc
     5281 taattctggg tctttccgcc agtgataatc cgcttcattc tgtacggttg aatgcggatt
     5341 cccagttgag tgtgcgtgta cttgcctata tggttgcacg ccgacttgag gcaaatctgt
     5401 tcttaattta ctcacattaa tttccatatt ctactcctta tcaattaaaa caactcattt
     5461 tttacaatcc agaaccagaa actcctttat ttctacctta caaagaagac aatcttagtc
     5521 acgattaagc ttgtagatag aacctcaaaa cgcactattt tgacactgta aataggactg
     5581 acaaggtctg cattctatct acaataacac cccagactaa aaagcttttc aaaagtatat
     5641 ttttacagtc tctatatgtc cttttcataa atactatact ttattatatc acataaaaga
     5701 agtcaaaagt ctgttaaact attttcaaca ccaaactaaa gaagagaaca caagtttttt
     5761 cgatgttcac tagaggaaat ggattttatt cagtaaatcc aactaggatt gcactttggt
     5821 tgccaaaatt gcctttcctt cttttatcaa gggatgacgg aatagtgaga agtacagttg
     5881 aactgtcatg gcaacccaga taagaggttc acaaaggata acacccttat atcctgccca
     5941 aggaataatc aaaaccacaa aaacgatttt tccgattagt tcaataaagc tagaaactag
     6001 aggaaggatc ttctgcccca agccctgcaa gcaattgcga taaatcaaca agaggctcaa
     6061 aatgggataa aaggctgaac tgatttgcag atagagactt ccattttcta tcaagtaacc
     6121 atctgtcgaa ctagccaaga aggaaaccaa ggctggactg gcaaaaaaga ggaaaataca
     6181 aacaaaaact gcccaggata tacttaaacg actgccgatt cgaagacctt gaacaatgcg
     6241 gtcaggtcgc ttagctccta gattctgaga agcaaaggtc gtcattgatg cagaaatagc
     6301 ggtcatagga agaagggcaa aggtcataat gcgtcgagct gccgtctggg cactaataat
     6361 cactgcacca aatgtattaa cagaaaactg taaaatcaca ctgccgatag atacaattga
     6421 actcatcaag cccatagcca aaccttgctc caagagatcc gcgtacaagc ttttgtccca
     6481 tttgaaatgt ttaaactgtg gcaagagttc tggcacactt ttacgaatat aataaaagca
     6541 gagaaccgct gataaacctt gcgaaataat ggtagcaagt cctgcggatt gaactcccag
     6601 atgcaattgc gtaataaaat agagatccag aaccacatta accaaggcag agaaaatcag
     6661 aaatcccagg gctgctagac tgtcaccaat agaccgcaac aagcctgcaa aaagattata
     6721 agcaaagctg acacctacac aggtcacaat catagaaata tattgataag attgaggaag
     6781 aatttctgca ggagtatcta agtattgcaa gagatgatac aagccaagaa agcccagcaa
     6841 cataactaga atgctcaaaa gagcacctaa aatccaagta gctgctactg cttccttgat
     6901 tttagtgaaa ttccgagccc cataataacg agcaatgaca atccccatgc cattgccaac
     6961 accaagtgta aaacctacaa tcaggtcaaa aatcgctgtc gtcgctccta ctgcagccaa
     7021 ggattcttga ccaagaaatc gtccaacaat caagacatca gcagtgttat agagctgttg
     7081 aaaaatattt gatagcaaaa ttggaaaggt gaagcttaag agcgagggaa gaatcggacc
     7141 atgtatcagg tccactgttc gt
//
LOCUS       DAVBBO010000079         7031 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ST1
            SAMEA2066453-rid20184263.denovo.079, whole genome shotgun sequence.
ACCESSION   DAVBBO010000079 DAVBBO010000000
VERSION     DAVBBO010000079.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2066453
            Sequence Read Archive: ERR351777
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 7031)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7031)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980402.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980402.1
            Genome Coverage       :: 176x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:17:33
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,141
            CDSs (total)                      :: 2,104
            Genes (coding)                    :: 1,953
            CDSs (with protein)               :: 1,953
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 16S)
            partial rRNAs                     :: 1 (23S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 151
            CDSs (without protein)            :: 151
            Pseudo Genes (ambiguous residues) :: 0 of 151
            Pseudo Genes (frameshifted)       :: 73 of 151
            Pseudo Genes (incomplete)         :: 76 of 151
            Pseudo Genes (internal stop)      :: 40 of 151
            Pseudo Genes (multiple problems)  :: 32 of 151
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7031
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2066453-rid20184263.denovo.079"
                     /strain="ST1"
                     /db_xref="taxon:1313"
     gene            226..6657
                     /locus_tag="VQU30_002016"
     CDS             226..6657
                     /locus_tag="VQU30_002016"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000750034.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S8 family serine peptidase"
                     /protein_id="HET2448056.1"
                     /translation="MKKSTVLSLTTAAVILAAYAPNEVVLADTSSSEDALNISDKEKV
                     VVDKETENKEKHEDIHNAIETSQDFKEKKTAVIEGKEVVSKNPVTDNNTSNEEARIKE
                     DSNQSQGDHTDSFVNKNTENPKKEDKVVYIAEFKDKESGEKAIKQLSNLKNTKVLYTY
                     DRIFNGSAIETTPDNLDKIKQIEGISSVERAQKVQPMMNHARKEIGVEEAIDYLKSIN
                     APFGKNFDGRGMVISNIDTGTDYRHKAMRIDDDAKASMRFKKEDLKGTDKNYWLSDKI
                     PHAFNYYNGGKITVEKYDDGRDYFDPHGMHIAGILAGNDTEQDIKNFNGIDGIAPNAQ
                     IFSYKMYSDAGSGFAGDETMFHAIEDSIKHNVDVVSVSSGFTGTGLVGEKYWQAIRAL
                     RKAGIPMVVATGNYATSASSSSWDLVANNHLKMTDTGNVTRTAAHEDAIAVASAKNQT
                     VEFDKVNIGGESFKYRNIGAFFDKNKITTNEDGTKAPSKLKFVYIGKGQDQDLIGLDL
                     RGKIAVMDRIYTKDLKNAFKKAMDKGARAIMVVNTVNYYNRDNWTELPAMGYEADEGT
                     KSQVFSISGDDGVKLWNMINPNKKTEVKRNNKEDFKDKLEQYYPIDMESFNSNKPNVG
                     DEKEIDFKFAPDTDKELYKEDIIVPAGSTSWGPRIDLLLKPDVSAPGKNIKSTLNVIN
                     GKSTYGYMSGTSMATPIVAASTVLIRPKLKEMLERPVLKNLKGDDKIDLTSLTKIALQ
                     NTARPMMDATSWKEKSQYFASPRQQGAGLINVANALRNEVVATFKNTDSKGLVNSYGS
                     ISLKEIKGDKKYFTIKLHNTSNRPLTFKVSASAITTDSLTDRLKLDETYKDEKSPYGK
                     QIVPEIHPEKVKGANITFEHDTFTIGANSSFDLNAVINVGEAKNKNKFVESFIHFESV
                     EEMEALNSNGKKINFQPSLSMPLMGFAGNWNHEPILDKWAWEEGSRSKTLGGYDDDGK
                     PKIPGTLNKGIGGEHGIDKFNPAGVIQNRKDKNTTSLDQNPELFAFNNQGINAPSSSG
                     SKIANIYPLDSNGNPQDAQLERGLTPSPLVLRSAEEGLISIVNTNKEGENQRDLKVIS
                     REHFIRGILNSKSNDAKGIKSSKLKVWGDLKWDGLIYNPRGREENAPESKDNQDPATK
                     IRGQFEPIAEGQYFYKFKYRLTKDYPWQVSYIPVKIDNTAPKIVSVDFSNPEKIKLIT
                     KDTYHKVKDQYKNETLFARDQKEHPEKFDEIANEVWYAGAALVNEDGEVEKNLEVTYA
                     GEGQGRNRKLDKDGNTIYEIKGAGDLRGKIIEVIALDGSSNFTKIHRIKFANHADEKG
                     MISYYLVDPDKDASKYEKLGEISEDKLKNAKSPEENTNNNQAKDEDSKPDEKSSVEGE
                     ASLEINKTISTIREFENKDLKKLIKKKFREVDDFTSETGKRIEEYDYKYDDKGNIIAY
                     DDGSALQYETEKLDEIKSKIYGVLSPSKDGHFEILGKISNVSKNAKVYYGNSYKSIEI
                     KATKYDSHSKTMIFDLYANINDIVDGLAFAGDMRLFVKDDNQIKAETKIRMPEKNKET
                     KAEYPYVSSYGNVIELGEGDLSKNKPDNLTKMESGKIYSDSEKQQYLLKDNIILRKGY
                     ALKVTTYNPGKTDMLEGNGVYSKEDIAKIQKANPNLRVLSETTIYADSRNVEDGRSTQ
                     AVLMSALDGFNIIRYQVFTFKMNDKGEAIDKDGNLVTDSSKLVLFGKDDKEYTGEDKS
                     NVEAIKEDGSMLFIDTKPVNLSMDKNYFNPSKSNKIYVRNPEFYLRGKISDKGGFNWE
                     LRVNESVVDNYLIYGDLHIDNTRDFNIKLNVKDGDIMDWGMKDYKANGFPDKVTDMDG
                     NVYLQTGYSDLNAKAVGVHYQFLYDNVKPEVNIDPKGNTSIEYADGKSVVFNINDKRN
                     NGFDGEIQEQHIYVNGKEYTSFDDIKQITDKTLNIKIVVKDFARNTTVKEFILNKDTG
                     EVSELKPHRVTVTIQNGKEMSSTIVSEEDFILPVYKGELEKGYQFDGWEISGFEGKKD
                     AGYVINLSKDTFIKPVFKKIEEKKEEENKPTFDVSKKKDNPQVNHSQLNESHRKEDLQ
                     REDHSQKSDSTKDVTATVLDKNNISSKSTTNNPNKLPKTGTASGAQTLLAAGIMFIVG
                     IFLGLKKKNQD"
BASE COUNT         2772 a          948 c         1356 g         1955 t
ORIGIN      
        1 taatcttatt ttttaacgtg tgctaaaaaa taaattaatg catgttaatt tttcttgaat
       61 taaatttttt taaatgatat actgttttta tggagagata acaattatat ataaatgtac
      121 tactctattt cctagataat acttagtaaa actttttata acaaaggcta gcaaagttaa
      181 agtttattat ctattggaag ttaaataaat atgtaaggaa ttaaaatgaa aaaaagtaca
      241 gtattgtcat taaccacagc tgcagttatt ttagcagcct atgcccctaa tgaggtagtc
      301 ttagcagaca catctagctc tgaagatgct ttaaacatct ctgataaaga aaaagtagta
      361 gtagataagg aaacagaaaa taaagagaaa catgaagata ttcataatgc tatagaaact
      421 tcacaggatt ttaaagagaa gaaaacagca gtcattgagg gaaaagaagt tgttagtaaa
      481 aatcctgtga cagacaataa cactagcaat gaagaagcaa gaatcaaaga agattccaat
      541 caatcccaag gagatcatac ggactcattt gtgaataaaa acacagaaaa tcccaaaaaa
      601 gaagataaag ttgtctatat tgctgaattt aaagataaag aatctggaga aaaagcaatc
      661 aagcaactat ccaatcttaa gaatacaaaa gttttatata cttatgatag aatttttaac
      721 ggtagtgcca tagaaacaac tccagataac ttggacaaaa ttaaacaaat agaaggtatt
      781 tcatcggttg aaagggcaca aaaagtccaa cccatgatga atcatgccag aaaggaaatt
      841 ggagttgagg aagctattga ttacctaaag tctatcaatg ctccgtttgg gaaaaatttt
      901 gatggtagag gtatggtcat ttcaaatatc gatactggaa cagattatag acataaggct
      961 atgagaatcg atgatgatgc caaagcctca atgagattta aaaaagaaga cttaaaagga
     1021 actgataaaa attattggtt gagtgataaa atccctcatg cgttcaatta ttataatggt
     1081 ggcaaaatca ctgtagaaaa atatgatgat ggaagggatt attttgaccc acatgggatg
     1141 catattgcag ggattcttgc tggaaatgat actgaacaag atatcaaaaa ctttaacggc
     1201 atagatggaa ttgcacctaa tgcacaaatt ttctcttaca aaatgtattc tgacgcagga
     1261 tctgggtttg cgggtgatga aacaatgttt catgctattg aagattctat caaacacaac
     1321 gttgatgttg tttcggtatc atctggtttt acaggaacag gtcttgtagg tgagaaatat
     1381 tggcaagcta ttcgggcatt aagaaaagca ggcattccaa tggttgtcgc tacgggtaac
     1441 tatgcgactt ctgcttcaag ttcttcatgg gatttagtag caaataatca tctgaaaatg
     1501 accgacactg gaaatgtaac acgaactgca gcacatgaag atgcgatagc ggtcgcttct
     1561 gctaaaaatc aaacagttga gtttgataaa gttaacatag gtggagaaag ttttaaatac
     1621 agaaatatag gggccttttt cgataagaat aaaatcacaa caaatgaaga tggaacaaaa
     1681 gctcctagta aattaaaatt tgtatatata ggcaaggggc aagaccaaga tttgataggt
     1741 ttggatctta ggggcaaaat tgcagtaatg gatagaattt atacaaagga tttaaaaaat
     1801 gcttttaaaa aagctatgga taagggtgca cgcgccatta tggttgtaaa tactgtaaat
     1861 tactacaata gagataattg gacagagctt ccagctatgg gatatgaagc ggatgaaggt
     1921 actaaaagtc aagtgttttc aatttcagga gatgatggtg taaagctatg gaacatgatt
     1981 aatcctaata aaaaaactga agtcaaaaga aataataaag aagattttaa agataaattg
     2041 gagcaatact atccaattga tatggaaagt tttaattcca acaaaccgaa tgtaggtgac
     2101 gaaaaagaga ttgactttaa gtttgcacct gacacagaca aagaactcta taaagaagat
     2161 atcatcgttc cagcaggatc tacatcttgg gggccaagaa tagatttact tttaaaaccc
     2221 gatgtttcag cacctggtaa aaatattaaa tccacgctta atgttattaa tggcaaatca
     2281 acttatggct atatgtcagg aactagtatg gcgactccaa tcgtggcagc ttctactgtt
     2341 ttgattagac cgaaattaaa ggaaatgctt gaaagacctg tattgaaaaa tcttaaggga
     2401 gatgacaaaa tagatcttac aagtcttaca aaaattgccc tacaaaatac tgcgcgacct
     2461 atgatggatg caacttcttg gaaagaaaaa agtcaatact ttgcatcacc tagacaacag
     2521 ggagcaggcc taattaatgt ggccaatgct ttgagaaatg aagttgtagc aactttcaaa
     2581 aacacggatt ctaaaggttt ggtaaactca tatggttcca tttctcttaa agaaataaaa
     2641 ggtgataaaa aatactttac aatcaagctt cacaatacat caaacagacc tttgactttt
     2701 aaagtttcag catcagcgat aactacagat tctctaactg acagattaaa acttgatgaa
     2761 acatataaag atgaaaaatc tccatatggt aagcaaattg ttccagaaat tcacccagaa
     2821 aaagtcaaag gagcaaatat cacatttgag catgatactt tcactatagg cgcaaattct
     2881 agctttgatt tgaatgcggt tataaatgtt ggagaggcca aaaacaaaaa taaatttgta
     2941 gaatcattta ttcattttga gtcagtggaa gaaatggaag ctctaaactc caacgggaag
     3001 aaaataaact tccaaccttc tttgtcgatg cctctaatgg gatttgctgg gaattggaac
     3061 cacgaaccaa tccttgataa atgggcttgg gaagaagggt caagatcaaa aacactggga
     3121 ggttatgatg atgatggtaa accgaaaatt ccaggaacct taaataaggg aattggtgga
     3181 gaacatggta tagataaatt taatccagca ggagttatac aaaatagaaa agataaaaat
     3241 acaacatccc tggatcaaaa tccagaatta tttgctttca ataaccaagg gatcaacgct
     3301 ccatcatcaa gtggttctaa gattgctaac atttatcctt tagattcaaa tggaaatcct
     3361 caagatgctc aacttgaaag aggattaaca ccttctccac ttgtattaag aagtgcagaa
     3421 gaaggattga tttcaatagt aaatacaaat aaagagggag aaaatcaaag agacttaaaa
     3481 gtcatttcga gagaacactt tattagagga attttaaatt ctaaaagcaa tgatgcaaag
     3541 ggaatcaaat catctaaact aaaagtttgg ggtgacttga agtgggatgg actcatctat
     3601 aatcctagag gtagagaaga aaatgcacca gaaagtaagg ataatcaaga tcctgctact
     3661 aagataagag gtcaatttga accgattgcg gaaggtcaat atttctataa atttaaatat
     3721 agattaacta aagattaccc atggcaggtt tcctatattc ctgtaaaaat tgataacacc
     3781 gcccctaaga ttgtttcggt tgatttttca aatcctgaaa aaattaagtt gattacaaag
     3841 gatacttatc ataaggtaaa agatcagtat aagaatgaaa cgctatttgc gagagatcaa
     3901 aaagaacatc ctgaaaaatt tgacgagatt gcgaacgaag tttggtatgc tggcgccgct
     3961 cttgttaatg aagatggaga ggttgaaaaa aatcttgaag taacttacgc aggtgagggt
     4021 caaggaagaa atagaaaact tgataaagac ggaaatacca tttatgaaat taaaggtgcg
     4081 ggagatttaa ggggaaaaat cattgaagtc attgcattag atggttctag caatttcaca
     4141 aagattcata gaattaaatt tgctaatcat gctgatgaaa aggggatgat ttcttattac
     4201 ctagtagatc ctgacaaaga tgcttctaaa tatgaaaaac ttggtgaaat ttctgaagat
     4261 aaactcaaaa atgcaaagag cccagaggaa aataccaata ataatcaagc taaggatgaa
     4321 gattcaaaac cagatgaaaa aagttcagtt gagggagaag ctagccttga aataaataaa
     4381 actatttcaa caattagaga gtttgaaaat aaagacctaa agaaactcat taaaaagaaa
     4441 tttagagaag ttgatgattt tacaagtgaa actggtaaga gaatagagga atacgattat
     4501 aaatacgatg ataagggaaa tattattgct tatgacgatg gtagtgcctt acaatatgaa
     4561 actgaaaaac ttgacgaaat aaaatcaaaa atttatggtg ttctaagccc atctaaagat
     4621 ggacactttg aaattcttgg aaagataagc aatgtttcta aaaatgccaa ggtatattat
     4681 ggaaatagct ataaatcgat agaaatcaaa gcgactaagt atgattcaca ttcaaaaacg
     4741 atgatatttg atttatacgc taatattaat gatattgtag atggattagc ttttgctgga
     4801 gatatgagat tatttgttaa agatgacaat caaataaaag ctgaaactaa gattagaatg
     4861 cctgaaaaaa ataaggaaac taaagcagaa tatccctatg tatcaagtta tgggaatgta
     4921 atcgaattag gagaaggaga tctttcaaag aacaaaccag acaatttaac taaaatggaa
     4981 tctggtaaaa tctattctga ttcagaaaaa caacaatatc tgttaaagga taacatcatt
     5041 ctaagaaaag gctatgcact aaaagtgact acctataatc ctggaaaaac ggatatgtta
     5101 gaaggaaatg gagtctatag caaggaagat atagcaaaaa tacaaaaggc caatcctaat
     5161 ctaagagtcc tttcagaaac aacaatttat gctgatagta gaaatgttga agatggaaga
     5221 agtacccaag ctgtattaat gtcggctttg gacggcttta acattataag gtatcaagtg
     5281 tttacattta aaatgaacga taaaggggaa gctatcgata aagacggaaa tcttgtgaca
     5341 gattcttcta aacttgtatt atttggtaag gatgataaag aatacactgg agaggataag
     5401 tccaatgtag aagctataaa agaagatggc tccatgttat ttattgatac caaaccagta
     5461 aacctttcaa tggataagaa ctactttaat ccatctaaat ctaataaaat ttatgtacga
     5521 aatccagaat tttatttaag aggtaagatt tctgataagg gtggttttaa ctgggaattg
     5581 agagttaatg aatcggttgt agataattat ttaatctacg gagatttaca cattgataac
     5641 actagagatt ttaatattaa gctgaatgtt aaagacggtg acatcatgga ctggggaatg
     5701 aaagactata aagcaaacgg atttccagat aaggtaacag atatggatgg aaatgtttat
     5761 cttcaaactg gctatagcga tttgaatgct aaagcagttg gagtccacta tcagttttta
     5821 tatgataatg ttaaacccga agtaaacatt gatcctaagg gaaatactag tatcgaatat
     5881 gctgatggaa aatctgtagt ctttaacatc aatgataaaa gaaataatgg attcgatggt
     5941 gagattcaag aacaacatat ttatgtaaat ggaaaagaat atacatcatt tgatgatatt
     6001 aaacaaataa cagacaagac actaaacatt aagattgttg taaaagattt tgcaagaaat
     6061 acaaccgtaa aagaattcat tttaaataaa gatacgggag aggtaagtga attaaaacct
     6121 catagggtaa ctgtgaccat tcaaaatgga aaagaaatga gttcaacgat agtgtcggaa
     6181 gaagatttta ttttacctgt ttataagggt gaattagaaa aaggatacca atttgatggt
     6241 tgggaaattt ctggtttcga aggtaaaaaa gacgctggct atgttattaa tctatcaaaa
     6301 gataccttta taaaacctgt attcaagaaa atagaggaga aaaaggagga agaaaataaa
     6361 cctacttttg atgtatcgaa aaagaaagat aacccacaag taaaccatag tcaattaaat
     6421 gaaagtcaca gaaaagagga tttacaaaga gaagatcatt cacaaaaatc tgattcaact
     6481 aaggatgtta cagctacagt tcttgataaa aacaatatca gtagtaaatc aactactaac
     6541 aatcctaata agttgccaaa aactggaaca gcaagcggag cccagacact attagctgcc
     6601 ggaataatgt ttatagtagg aatttttctt ggattgaaga aaaaaaatca agattaagac
     6661 aaaagctata gaaaaaaatg gtttatgtac tgagattaga tagtgaggtg atgacatagt
     6721 tttgtgaaaa cagccattta taactcaatt atttagttta cttcactatt gatactattt
     6781 ggagttatta atggacttag tttagataac taatgaattg attgaaaggg ttagtattga
     6841 caatattggt catattgatt agaaaataga gtctatcaaa atttaaaggc taatagaggt
     6901 gatgagacaa tttcggctct ttgtcaactg tagtgggttg aagtcagcta agctcgagaa
     6961 aggacaaatt ttgtcctttc ttttttgata ttcagagcga tgaaaatccg ttttttgaag
     7021 ttttcaaagt t
//
LOCUS       DAVBBO010000080         6905 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ST1
            SAMEA2066453-rid20184263.denovo.080, whole genome shotgun sequence.
ACCESSION   DAVBBO010000080 DAVBBO010000000
VERSION     DAVBBO010000080.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2066453
            Sequence Read Archive: ERR351777
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 6905)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6905)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980402.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980402.1
            Genome Coverage       :: 176x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:17:33
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,141
            CDSs (total)                      :: 2,104
            Genes (coding)                    :: 1,953
            CDSs (with protein)               :: 1,953
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 16S)
            partial rRNAs                     :: 1 (23S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 151
            CDSs (without protein)            :: 151
            Pseudo Genes (ambiguous residues) :: 0 of 151
            Pseudo Genes (frameshifted)       :: 73 of 151
            Pseudo Genes (incomplete)         :: 76 of 151
            Pseudo Genes (internal stop)      :: 40 of 151
            Pseudo Genes (multiple problems)  :: 32 of 151
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6905
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2066453-rid20184263.denovo.080"
                     /strain="ST1"
                     /db_xref="taxon:1313"
     gene            <1..332
                     /locus_tag="VQU30_002017"
     CDS             <1..332
                     /locus_tag="VQU30_002017"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HET2448057.1"
                     /translation="GLTNGELIAPMTYEETMTSDFFEVWFQKFFLPTLTTPSVIIMDN
                     VRFHRMGKLELLCEEFGHKLLPLPPYSPEYNPIEKTWVHIKKHLKKVLPSCNTFYEAL
                     LSCSCFN"
     gene            393..1355
                     /locus_tag="VQU30_002018"
     CDS             393..1355
                     /locus_tag="VQU30_002018"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsX-like permease family protein"
                     /protein_id="HET2448058.1"
                     /translation="MNMSNITIDGQEMDLSQTMPSYAQVVSLYDDTSISVSSNETDKV
                     LAGSLYTDTNEQGLTIPSSLLKNWNEQTGKNLTANDLIGKSVSASIVESAAETSKIAQ
                     FQTKIVRVINDEDDMEDSNSFMLSHQMETILKEAGFTKAVSYFILELKDPSQTKVVTE
                     ELQKNKKYTVLSQQRVLDIVIIFIRVIQGLLIVLSSQAIVVAAVMIGIIIYINIMQRS
                     KEIGVMKAVGYQNRDVKGIFIYEAIWIVGIALLLAFLVAQGVGSLANAIVSHFYPSIT
                     KVFELNLLSVLGTLVFALLLGYVSAYFPARKISKMDPVEPLRYE"
     gene            1532..2539
                     /gene="gap"
                     /locus_tag="VQU30_002019"
     CDS             1532..2539
                     /gene="gap"
                     /locus_tag="VQU30_002019"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008090210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I glyceraldehyde-3-phosphate dehydrogenase"
                     /protein_id="HET2448059.1"
                     /translation="MVVKVGINGFGRIGRLAFRRIQNVEGVEVTRINDLTDPVMLAHL
                     LKYDTTQGRFDGTVEVKEGGFEVNGKFIKVSAERDPEQIDWATDGVEIVLEATGFFAK
                     KEAAEKHLKGGAKKVVITAPGGNDVKTVVFNTNHDVLDGTETVISGASCTTNCLAPMA
                     KALQDNFGVVEGLMTTIHAYTGDQMILDGPHRGGDLRRARAGAANIVPNSTGAAKAIG
                     LVIPELNGKLDGSAQRVPTPTGSVTELVAVLEKNVTVDEVNAAMKAASNESYGYTEDP
                     IVSSDIVGMSYGSLFDATQTKVLDVDGKQLVKVVSWYDNEMSYTAQLVRTLEYFAKIA
                     K"
     gene            complement(2606..3442)
                     /locus_tag="VQU30_002020"
     CDS             complement(2606..3442)
                     /locus_tag="VQU30_002020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000216776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RluA family pseudouridine synthase"
                     /protein_id="HET2448060.1"
                     /translation="MTVKQLLEEQLLIPRKIRHFLRIKKHILINQEEVHWNEIVNPGD
                     VCQLTFDEEDYPQKTIPWGNPDLVQEVYQDQYLIIVNKPEGMKTHGNQPNEIALLNHV
                     STYVGQTCYVVHRLDMETSGLVLFAKNPFILPILNRLLEKKEISREYWALVDGNINRK
                     ELVFRDKIGRDRHDRRKRIVDAKNGQYAETYVSRLKQFSNKTSLARCKLKTGRTHQIR
                     VHLSHHNLPILGDPLYNSKSKTSRLMLHAFRLSFTHPLTLEKLTFTTLSNTFEKELKK
                     NG"
     gene            3568..5763
                     /locus_tag="VQU30_002021"
     CDS             3568..5763
                     /locus_tag="VQU30_002021"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000762602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein"
                     /protein_id="HET2448061.1"
                     /translation="MKLDKLFEKFLSLFKKETSELEDSDSTILRRSRSDRKKLAQVGP
                     IRKFWRRYHLTKIILILGLSAGLLVGIYLFAVAKSTNVNDLQNALKTRTLIFDREEKE
                     AGALSGQKGTYVELTDISKNLQNAVIATEDRSFYKNDGINYGRFFLAIVTAGRSGGGS
                     TITQQLAKNAYLSQDQTVERKAKEFFLALELSKKYSKEQILTMYLNNAYFGNGVWGVE
                     DASKKYFGVSASEVSLDQAATLAGMLKGPELYNPLNSVEDSTNRRDTVLQNMVAAGYI
                     DKNQETEAAEVDMASQLHDKYEGKISDYRYPSYFDAVVNEAVSKYNLTEEEIVNNGYR
                     IYTELDQNYQANMQIVYENTSLFPRAEDGTFAQSGSVALEPKTGGVRGVVGQVADNDK
                     TGFRNFNYATQSKRSPGSTIKPLVVYTPAVEAGWALNKQLDNHTMQYDSYKVDNYAGI
                     KTSREVPMYQALAESLNLPAVAAVNDLGVDKAFEAGEKFGLNMEKVDRVLGVALGSGV
                     ETNPLQMAQAYAAFANEGLMPEAHFISRIENASGQVIASHKNSQKRVIDKSVADKMTS
                     MMLGTFTNGTGISSSPADYIMAGKTGTTEAVFNPEYTSDQWVIAYTPDVVISHWLGFP
                     TTDENHYLAGSTSNGAAHVFRNIANTILPYTPGSTFTVENAYKQNGIAPANTKRQVQT
                     NDNSQTDDNLSDIRGRAQSLVDEASRAISDAKIKEKAQTIWDSIVNLFR"
     gene            5816..5968
                     /gene="rpmG"
                     /locus_tag="VQU30_002022"
     CDS             5816..5968
                     /gene="rpmG"
                     /locus_tag="VQU30_002022"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015912025.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L33"
                     /protein_id="HET2448062.1"
                     /translation="MALKKASLACAVCGSRNYSIKISGNPKPTRLEVNKFCKHCGKYT
                     THRETR"
     gene            5978..6154
                     /gene="secE"
                     /locus_tag="VQU30_002023"
     CDS             5978..6154
                     /gene="secE"
                     /locus_tag="VQU30_002023"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001211016.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecE"
                     /protein_id="HET2448063.1"
                     /translation="MRFIGDIFRLLKDTTWPTRKESWRDFRSIMEYTAFFVVIIYIFD
                     QLIVSGLIRFINIF"
     gene            6210..6746
                     /gene="nusG"
                     /locus_tag="VQU30_002024"
     CDS             6210..6746
                     /gene="nusG"
                     /locus_tag="VQU30_002024"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000376740.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription termination/antitermination
                     protein NusG"
                     /protein_id="HET2448064.1"
                     /translation="MDSFDKGWFVLQTYSGYENKVKENLLQRAQTYNMLDNILRVEIP
                     TQTVQVEKNGKRKEVEENRFPGYVLVEMVMTDEAWFVVRNTPNVTGFVGSHGNRSKPT
                     PLLEQEIRDILVSMGQTVQEFDFDVEIGQTVRIIDGAFADYTGKITEIDNNKVKMIIS
                     MFGNDTVAEVNLNQIAEL"
BASE COUNT         2149 a         1201 c         1499 g         2056 t
ORIGIN      
        1 caggtctaac aaatggtgaa ttaatcgctc caatgactta cgaagagacg atgacgagcg
       61 acttttttga agtatggttt cagaagtttt tcttaccaac attaaccaca ccatcggtta
      121 ttattatgga taatgtaaga ttccatagaa tggggaagct agaactcttg tgtgaagagt
      181 ttgggcataa acttttacct cttcctccct actcacctga gtacaatcct attgagaaaa
      241 catgggttca tatcaaaaag cacctcaaaa aggtattacc aagttgcaat accttttacg
      301 aggctctttt gtcttgttct tgtttcaatt gactatatat cacggataca gttgggaaag
      361 aagctattaa acatttggag agtccttttg ggatgaacat gtcaaatatt actatagatg
      421 ggcaagaaat ggatctgagt caaacgatgc cttcttatgc tcaagtagtg agtctttatg
      481 atgatacaag tatctctgtt agtagtaatg agacggacaa agtgttggct ggctccctct
      541 atactgatac aaatgaacag ggattaacga ttccaagcag tttactaaaa aattggaatg
      601 aacagacagg aaaaaatttg acagctaatg atcttattgg caaatcagtc tcagccagca
      661 ttgtagaaag tgctgccgaa actagtaaga ttgctcaatt tcaaacgaag attgtacgtg
      721 taatcaatga tgaagatgac atggaggaca gcaacagttt catgctgtct catcaaatgg
      781 aaacgatttt gaaagaggct ggatttacga aagctgtatc ttattttatc ttggaactca
      841 aagatccatc acagacaaaa gtagtaacag aagaattaca gaaaaataag aagtatactg
      901 tgctttctca acagagagtt cttgatattg tgattatctt tattcgtgtt attcagggat
      961 tattgattgt gctttcatca caagctattg tggtagcagc ggttatgatt ggtatcatta
     1021 tttacatcaa tatcatgcag cgttccaagg aaataggtgt catgaaggca gttggttatc
     1081 agaatcgtga tgtcaaagga atttttattt acgaggctat ctggattgta ggcatcgcct
     1141 tgctgctggc atttttggtt gcacaagggg tgggaagttt ggcgaatgcg attgtaagtc
     1201 acttttaccc atccatcact aaagtttttg aattaaatct tttatctgtt ttaggaactc
     1261 tagttttcgc tctattactt ggttatgtct cagcctactt cccggcgcgt aagattagta
     1321 aaatggatcc tgtagaaccg ttacgctatg aatagtaagg gattccttga tttacagtct
     1381 taaaaagaaa ctaacataga aaaacaatgg acatacttgc aattcaactc aaatagttgt
     1441 ataataggtt tgttgaaagg tgatttgtag tgattcaagt tactcttttc acaataaaaa
     1501 tttcatgatt ttcataagga ggaaatcact aatggtagtt aaagttggta ttaacggttt
     1561 cggacgtatc ggtcgtcttg ctttccgtcg tatccaaaac gtagaaggtg ttgaagttac
     1621 acgcatcaac gaccttacag atccagttat gcttgcacac ttgttgaaat acgacacaac
     1681 tcaaggtcgt ttcgacggta ctgttgaagt taaagaaggt ggatttgaag ttaacggtaa
     1741 attcatcaaa gtttctgctg aacgtgatcc agaacaaatc gactgggcta ctgacggtgt
     1801 agaaatcgtt cttgaagcta ctggtttctt tgctaagaaa gaagcagctg aaaaacacct
     1861 taaaggtgga gctaaaaaag ttgttatcac tgctcctggt ggaaacgacg ttaaaacagt
     1921 tgtattcaat actaaccacg acgttcttga cggtactgaa acagttatct caggtgcttc
     1981 atgtactaca aactgcttgg ctccaatggc taaagctctt caagacaact ttggtgttgt
     2041 tgaaggattg atgactacta tccacgctta cactggtgac caaatgatcc ttgacggacc
     2101 acaccgtggt ggtgaccttc gccgtgctcg cgctggtgct gcaaacatcg ttcctaactc
     2161 aactggtgct gcaaaagcta tcggtcttgt aatcccagaa ttgaatggta aacttgatgg
     2221 atctgcacaa cgcgttccaa ctccaactgg atcagttact gaattggtag cagttcttga
     2281 aaagaacgtt actgttgatg aagtgaacgc agctatgaaa gcagcttcaa acgaatcata
     2341 cggttacaca gaagatccaa tcgtatcttc agatatcgta ggtatgtctt acggttcatt
     2401 gtttgacgca actcaaacta aagttcttga cgttgacggt aaacaattgg ttaaagttgt
     2461 atcatggtac gacaacgaaa tgtcatacac tgcacaactt gttcgtactc ttgaatactt
     2521 cgcaaaaatt gctaaataat tcttgagttg atagaaagca aggctttgtg gtcttgcttt
     2581 ttatatggaa aaatggatga cacgatcatc cattcttttt taattctttt tcaaatgtat
     2641 ttgaaagggt agtgaaagtt agcttctcta aagtaagtgg gtgggtaaag gaaagtcgga
     2701 aggcatgaag cataagccga cttgtctttg atttactatt atagagaggg tcgcccagga
     2761 taggaagatt atgatgcgaa aggtgcacac gaatctgatg ggttcgccct gtctttagct
     2821 tgcaacgagc caaggaagtc ttgtttgaga attgctttaa tctgcttaca tacgtttcag
     2881 catattgccc attttttgca tcaactattc tttttctacg atcatggcga tcacgtccaa
     2941 ttttgtctct gaaaacaagt tcttttctgt tgatatttcc atcaactaga gcccaatatt
     3001 ctctagaaat ctcttttttc tccaataagc gattgagaat gggcaggata aaaggatttt
     3061 tggcaaagag aactaagcca ctggtttcca tgtccagacg atgaacgaca tagcaggttt
     3121 ggccaacata ggtactgaca tggttaagaa gggcaatttc gtttggttga ttaccatgcg
     3181 ttttcatccc ctctggtttg tttacaataa tcaagtattg atcttgataa acttcctgca
     3241 ctaagtctgg gttgccccaa gggatcgtct tttggggata atcttcctcg tcaaaagtca
     3301 actggcaaac atctccagga tttacgattt cgttccagtg gacttcttct tgatttatca
     3361 aaatatgttt cttgattctc aaaaaatgac ggatttttct agggatgagg agttgttcct
     3421 caagtaattg ctttaccgtc atttgaggta gagaggcggg taatgtaaat gtgaattgca
     3481 tacagatatt gtaacaaaaa aagccctatt tggataggaa atagctaaat tcttgtcttc
     3541 ctatgatgaa gatgataaaa taaacgcatg aaattagata aattatttga gaaatttctt
     3601 tctcttttta aaaaagaaac aagtgaacta gaggactctg attctactat cttacgtcgc
     3661 tctcgtagtg atcgaaaaaa attagcccaa gtaggtccga ttcgaaaatt ctggcgtcgt
     3721 tatcatctaa caaagattat ccttatacta ggtttgagtg caggcttgct agttggaatc
     3781 tatttgtttg ctgtagccaa gtcgaccaat gtcaatgatt tgcaaaatgc cttgaaaact
     3841 cggactctta tttttgaccg tgaagaaaaa gaggctggtg ccttgtctgg tcaaaaggga
     3901 acctatgttg agctgactga tatcagtaaa aacttgcaga atgctgttat tgcgacagaa
     3961 gaccgttctt tctataaaaa tgacgggatt aactatggcc gtttcttctt ggctattgtc
     4021 actgctggac gttcaggtgg tggctctacc attacccaac agctggctaa aaacgcctat
     4081 ttatcacagg atcaaactgt tgagagaaaa gcgaaagaat ttttccttgc cttagaatta
     4141 agcaaaaaat atagtaagga gcaaattcta accatgtacc ttaacaacgc ttattttgga
     4201 aatggtgtgt ggggtgtaga agatgcgagt aagaaatact ttggagtttc tgcatcagaa
     4261 gtgagtctgg atcaagctgc gactctggca gggatgctca aggggccgga actgtataat
     4321 cccttgaatt ccgtagaaga ttctactaat cggcgcgata ctgtcttgca gaatatggtt
     4381 gcagcaggat atattgataa aaaccaagaa accgaagctg ctgaagttga tatggcttcg
     4441 caattgcacg ataagtatga aggaaaaatc tcagattacc gttacccctc ttattttgat
     4501 gcggtggtta atgaagctgt ttccaagtat aatctaacag aggaagagat tgtcaataat
     4561 ggctaccgca tttacacaga gctggaccaa aactaccaag caaatatgca gattgtttat
     4621 gaaaacacat cgctatttcc gagggcagag gatggaacgt ttgctcaatc aggaagtgta
     4681 gctctcgaac cgaaaacagg gggagttcgt ggagttgtcg gtcaagttgc tgacaatgat
     4741 aaaactggat tccggaattt caactatgca acccaatcaa agcgtagtcc tggttctaca
     4801 attaagcctt tagttgttta tacgccagca gttgaagcag gctgggcttt gaataagcag
     4861 ttggataacc ataccatgca gtatgacagc tataaggttg ataactatgc agggatcaaa
     4921 acgagtcgag aagttcctat gtatcaagcc ttggcagaat cgcttaatct acctgctgtt
     4981 gccgctgtta atgatttggg tgtcgacaag gcttttgagg caggcgaaaa attcggactc
     5041 aacatggaaa aggtcgaccg tgttcttggt gtcgccttgg gaagcggtgt tgaaaccaac
     5101 cctcttcaaa tggctcaagc atacgctgcc tttgcaaatg aaggtttaat gcctgaagct
     5161 cattttatta gtagaattga aaatgctagt ggacaagtta ttgcgagtca taaaaattca
     5221 caaaaacggg tgattgataa gtctgtagct gacaagatga ccagtatgat gttggggact
     5281 ttcaccaacg gtaccggtat tagttcatcg cctgcagact atattatggc agggaaaact
     5341 ggaacaactg aagcagtttt caatccggag tacacaagtg accagtgggt aattgcttat
     5401 actccggatg tagtgattag ccactggctt ggctttccta ccactgatga aaatcactat
     5461 ctagctggct ctacttcaaa cggtgcagct catgtcttta gaaacattgc caataccatt
     5521 ttaccttata cgccaggaag tacctttacg gttgaaaatg cttataagca aaatggaatt
     5581 gcaccagcca atacaaaaag acaagtacaa accaatgata atagccagac agatgataat
     5641 ttgtctgata ttcgagggcg tgcgcaaagt ctagtagatg aggctagccg ggctatctca
     5701 gatgcgaaga ttaaggaaaa ggctcaaaca atatgggatt cgatagtcaa tctatttcgc
     5761 taagatgctt gtcaaagcct agctttcttg ttataatgga taggatggag gcgttatggc
     5821 actaaaaaaa gcaagcctag cttgtgcggt ttgtggttcg agaaactatt caatcaagat
     5881 cagcggaaac cccaagccta cacgactaga agtaaataaa ttttgtaagc attgtggcaa
     5941 gtacactaca cacagagaaa cgagatagga gagagcgatg cgttttattg gagatatttt
     6001 tagacttctt aaagacacaa cgtggccaac tcgcaaggaa agctggagag attttcgttc
     6061 tatcatggaa tacacagctt tctttgtagt aattatttac atttttgacc agttgattgt
     6121 ttcaggtttg attcgattta ttaacatttt ttagaagatt agtggagtta attacactag
     6181 aaatcttcta tattatgaaa ggaaatatca tggatagttt tgataaaggg tggtttgttt
     6241 tacaaactta ttctggttat gaaaataagg tgaaagaaaa tctattacaa cgtgcacaaa
     6301 cctacaatat gttggataat attctacgcg ttgaaattcc aacacaaaca gtgcaagttg
     6361 aaaaaaatgg aaagagaaaa gaagtagaag aaaatcgctt tccaggttat gttcttgtag
     6421 aaatggtcat gacagatgaa gcttggtttg ttgttcgaaa cacaccaaat gttacaggat
     6481 ttgtcggatc acacgggaac agatcaaaac caactccatt attggaacaa gaaattcgtg
     6541 acattttggt atctatggga caaactgttc aagaatttga tttcgatgtt gagattggtc
     6601 aaactgtacg tattattgat ggtgcttttg cagactacac tggtaagatt acagaaattg
     6661 ataataacaa agtgaaaatg attatctcta tgtttggtaa tgacacagtt gcagaagtaa
     6721 acctaaacca aatcgcagaa ttataaccct gagagaggct ggagcctctc ttttttgtgc
     6781 agtttaggag ctaaagggaa cagaatggag aaaatgtaac aaatgtgttt tctaatctgt
     6841 tagactgtat ctagaaaggg gaaaattatg attaaagaat tgtatgaaga agtccaaggg
     6901 actgt
//
LOCUS       DAVBBO010000081         6834 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ST1
            SAMEA2066453-rid20184263.denovo.081, whole genome shotgun sequence.
ACCESSION   DAVBBO010000081 DAVBBO010000000
VERSION     DAVBBO010000081.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2066453
            Sequence Read Archive: ERR351777
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 6834)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6834)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980402.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980402.1
            Genome Coverage       :: 176x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:17:33
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,141
            CDSs (total)                      :: 2,104
            Genes (coding)                    :: 1,953
            CDSs (with protein)               :: 1,953
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 16S)
            partial rRNAs                     :: 1 (23S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 151
            CDSs (without protein)            :: 151
            Pseudo Genes (ambiguous residues) :: 0 of 151
            Pseudo Genes (frameshifted)       :: 73 of 151
            Pseudo Genes (incomplete)         :: 76 of 151
            Pseudo Genes (internal stop)      :: 40 of 151
            Pseudo Genes (multiple problems)  :: 32 of 151
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6834
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2066453-rid20184263.denovo.081"
                     /strain="ST1"
                     /db_xref="taxon:1313"
     gene            complement(201..1625)
                     /locus_tag="VQU30_002025"
     CDS             complement(201..1625)
                     /locus_tag="VQU30_002025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000199391.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-dependent glyceraldehyde-3-phosphate
                     dehydrogenase"
                     /protein_id="HET2448065.1"
                     /translation="MTRYQNLVNGKWKSSEQEITIYSPINQEELGTVPAMTQTEADEA
                     MQAARAALPAWRALSAIERAAYLHKTAAILERDKEKIGTILAKEVAKGIKAAIGEVVR
                     TADLIRYAAEEGLRITGQAMEGGGFEAASKNKLAVVRREPVGIVLAIAPFNYPVNLSA
                     SKIAPALIAGNVVMLKPPTQGSISGLLLAKAFEEAGIPAGVFNTITGRGSEIGDYIIE
                     HKEVNFINFTGSTPIGERIGRLAGMRPIMLELGGKDAALVLEDADLEHAAKQIVAGAF
                     SYSGQRCTAIKRVIVLESVADKLATLLQEEVSKLTVGDPFDNADITPVIDNASADFIW
                     GLIEDAQEKEAQALTPIKREGNLLWPVLFDQVTKDMKVAWEEPFGPVLPIIRVASVEE
                     AIAFANESEFGLQSSVFTNDFKKAFEIAEKLEVGTVHINNKTQRGPDNFPFLGVKGSG
                     AGVQGIKYSIEAMTNVKSIVFDVK"
     gene            complement(2169..4448)
                     /gene="pulA"
                     /locus_tag="VQU30_002026"
     CDS             complement(2169..4448)
                     /gene="pulA"
                     /locus_tag="VQU30_002026"
                     /EC_number="3.2.1.41"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000283081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I pullulanase"
                     /protein_id="HET2448066.1"
                     /translation="MYNYPMRIHYHRKNGEYDTCSFVKSQDQRIDLLTYKEDYFGALF
                     SFEHPSSHVIESLNFVVHTGQTSKEYSIRFNHYPLLTEVWILEGDDRIYYSENPAIAS
                     PFYKNQNPFAFDKAINSASFDHHWGYQGELGCRVEDNQAHFSLWSPTATEVQVVVYES
                     AANDAPVWKTFEMKRGNSYSYNHKDNTIGVWSLDVEEDLVGKTYQYQVQFPHHQTLTR
                     DPYTIATSPDGKRSAILSHVEKQVENFEVKHGSEATWRLENPCKAVICEMHIRDLTKS
                     PTSGVDEHLRGTFLGAAQAGTVNQYGQSTAFDYIKKLGYNYVQLQPIADRHKEYDEDG
                     NVTYNWGYDPQNYNAPETSFSTNPDDPAQVIRDLKVMVQAYHDAGIGVIMDVVYNHTF
                     SVVDAPFQTTVPDYYYRMNPDGTFQNGTGVGNETASEHEMFRKYMIDSLLYWVQEYNI
                     DGFRFDLMGIHDVKTMQMIRQSLDEIDSNIILYGEGWDMGTGLAPYDKAKKDNAYQMP
                     NIGFFNDNQRDAVKGGEVYGAIKSGFVSGAATEPILAKAILGSRELGSYTHPNQVLNY
                     VEAHDNYNLHDLLATLHPDQSSEQIMRKVETATAMNLLMQGMAFMEIGQEFGRTKLVA
                     TGENGELTHDDRERAMNSYNAPDSVNQVNWNLINERQDSIEFIRQVIRLKTKTGAFSY
                     SSYDEIYHHVFVHSAIEHSGCLIYEVHGKEHLLVVVNAKSEPYQFENAGNLAMLVTNS
                     RSKEDNVLNDISLAVLSVL"
     gene            complement(4560..6518)
                     /gene="ligA"
                     /locus_tag="VQU30_002027"
     CDS             complement(4560..6518)
                     /gene="ligA"
                     /locus_tag="VQU30_002027"
                     /EC_number="6.5.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001042597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-dependent DNA ligase LigA"
                     /protein_id="HET2448067.1"
                     /translation="MNKRMNELVALLNRYATEYYTSDNPSVSDSEYDRLYRELVELET
                     AYPEQVLADSPTHRVGGKVLDGFEKYSHQYPLYSLQDAFSREELDAFDARVRKEVAHP
                     TYICELKIDGLSISLTYEKGILVAGVTRGDGSIGENITENLKRVKDIPLTLPEELDIT
                     VRGECYMPRASFDQVNQVRQENGEPEFANPRNAAAGTLRQLDTAVVAKRNLATFLYQE
                     ASPSTRDSQEKGLKYLEQLGFVVNPKRILAENIDEIWNFIQEVGQERENLPYDIDGVV
                     IKVNDLASQEELGFTVKAPKWAVAYKFPAEEKEAQLLSVDWTVGRTGVVTPTANLTPV
                     QLAGTTVSRATLHNVDYIAEKDIRKDDTVIVYKAGDIIPAVLRVVESKRVSEEKLDIP
                     TNCPSCNSDLLHFEDEVALRCINPRCPAQIMEGLIHFASRDAMNITGLGPSIVEKLFA
                     ANLVKDVADIYRLQEEDFLLLEGVKEKSAAKLYQAIQASKENSAEKLLFGLGIRHVGS
                     KASQLLLQYFHSIENLSQADSEEVASIESLGGVIAKSLQTYFATEGSEILLRELKETG
                     VNLDYKGQTVVADAALSGLTVVLTGKLERLKRSEAKSKLESLGAKVTGSVSKKTDLVV
                     VGADAGSKLQKAQELGIQVRDEAWLESL"
     gene            complement(6611..>6834)
                     /locus_tag="VQU30_002028"
     CDS             complement(6611..>6834)
                     /locus_tag="VQU30_002028"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001083019.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HET2448068.1"
                     /translation="FFTQVQTKVESEFLGRVLSTIFTLAILFMPIAKGFMTVLPSVHL
                     SSFLIIGSGVIILSCISFIYVRTHFEKLI"
BASE COUNT         2022 a         1502 c         1239 g         2071 t
ORIGIN      
        1 actatatata gtaaaatgaa ataataacag gacaaatcga tcaggacagt caaatcgatt
       61 tctaacaatg ttttagaagt aaatctgtac tattctagtt tcaatatact ataataccaa
      121 aaagttcgta ttttttctat aattattatt attttatagc aaaaaataaa accaggaaaa
      181 caatttcctg attttacacg ttatttcaca tcaaaaacaa tggatttgac atttgtcatc
      241 gcttcaatgc tatatttaat tccttgcact ccagctccag aacctttgac accaaggaat
      301 gggaaattat ctggaccacg ctgggtttta ttattaatgt ggactgtacc tacttcaagt
      361 ttttcagcaa tttcaaaggc ttttttgaaa tcatttgtaa agactgatga ttgaaggccg
      421 aattcagatt cgttggcaaa ggcaatagct tcctctacac tagccacacg aatgattggt
      481 aaaacaggac caaatggctc ttcccatgcc actttcatat cttttgtaac ttggtcaaaa
      541 agcactggcc agaggagatt gccctcacgt ttgattggtg taagagcctg agcctctttt
      601 tcttgtgcat cctcaatcaa gccccaaatg aagtcggctg aagcattgtc aataacaggt
      661 gtaatatcag cattgtcaaa tggatcacca actgttaatt tagaaacttc ttcctgaagc
      721 aaagtagcta atttatctgc tacactttcg agaacaatga cacgtttaat ggccgtgcaa
      781 cgttgtcctg agtagctaaa ggctcccgca acaatttgct tggcagcatg ttccaaatct
      841 gcatcttcta gtacaagagc tgcatctttc ccaccaagtt ccaacatgat aggacgcata
      901 ccagctaaac gaccaatacg ttctccaata ggagttgaac ctgtaaagtt gatgaagttg
      961 acttctttgt gctcaatgat ataatcccca atttctgaac cacgacctgt aatggtgttg
     1021 aaaacacctg ccggaatccc tgcttcttca aatgctttag ccaacaagag tccagaaatg
     1081 gaaccttgtg ttggtggctt caacatgacc acattccctg caatcaaggc aggtgcaatt
     1141 ttagaagcag ataaattaac tggataatta aagggagcaa tcgctagcac gataccaact
     1201 ggttcacgac ggacaacagc cagtttgttt ttacttgctg cctcaaaacc accaccttcc
     1261 attgcttgtc cagtgatacg gagaccttcc tcagcagcat aacgaatcaa gtctgctgta
     1321 cgcactactt ctccaattgc tgctttaatc ccttttgcta cttctttggc aaggatagta
     1381 ccaatttttt ccttatcgcg ttctaaaata gctgctgttt tatgcaaata agccgcacgt
     1441 tcaattgctg ataaagctcg ccatgctggc agggctgcac gcgcagcttg catagcctca
     1501 tcagcttcag tctgagtcat ggctggaact gtacccaatt cttcttgatt gattggtgaa
     1561 taaatcgtaa tttcttgttc agatgatttc cattttccat ttactaaatt ctgatatctt
     1621 gtcaaattct tgtcctcctg aaaatgatta agatatattt taccaaattt tcagaaaata
     1681 acaacccttt ttgcaaaatt tttgagatta ttttcacaag cttgattttt caaagtatac
     1741 tcaataaaaa taaaaaaatc cactacgtca aggcgaggct aatgtggttt gaagaaattt
     1801 tcgaagagcg tgaatgagta tcatctatag taaaataaaa aaactgaaca atttggttgg
     1861 ggacagccaa accaatttct cacaatgttt cagaaacaag ggtgtgctat tccaatttca
     1921 gcctactata actgtcatag attgctgaaa caaagtctag gtaaaagtct tcataataaa
     1981 aagacctcct atcaaatgtt caaaaacttt gataggaggt cttgtttcgt gaaaatattt
     2041 atcaaatttt ctatacaagt gagctgttag ccaggttctt tctattcttt caatttcaat
     2101 gaatggattt tttaccaata ctcataactg ggaatttttc tgtctaaaaa tagcgagata
     2161 gatggtattt ataaaacact caagacagct agactaatat catttaaaac attatcttct
     2221 tttgagcgac tgttggttac caacatagct aaatttcctg cattttcaaa ttgatagggt
     2281 tctgatttag cattcacaac taccaagagg tgttctttgc cgtgaacttc atagataagg
     2341 cagccgctat gttcaatcgc agaatgcaca aagacatgat ggtaaatttc atcatagcta
     2401 gagtaagaaa aggcaccagt ttttgtcttc aatcggatga cttgacggat aaactcaata
     2461 ctgtcttgac gctcattaat caagttccag ttcacttggt tcacactgtc aggagcatta
     2521 tagctattca tcgcacgctc tctatcatca tgggtcaact caccattttc accagtcgca
     2581 accagtttgg tacgaccaaa ttcttgaccg atttccataa aggccatccc ctgcatgagc
     2641 agattcatgg ctgtggcagt ttcgaccttg cgcatgattt gctctgaact ttggtctgga
     2701 tgaagggttg ccaataaatc gtgaagattg taattgtcat gggcttctac atagttaagc
     2761 acctgatttg gatgtgtata gcttcctaat tcacgacttc ctaggattgc tttagctaga
     2821 attggctctg tcgcagcacc actgacaaaa cctgacttga tagcaccata aacttctccc
     2881 cctttgacag catcgcgctg attgtcatta aagaaaccaa tatttggcat ctggtaggca
     2941 ttgtccttct tggccttatc ataaggggca agacctgttc ccatatccca tccttctcca
     3001 tagaggataa tgttggagtc aatttcatcc aagctttgac gaatcatctg catggtcttg
     3061 acatcatgaa tccccatcaa gtcaaaacgg aagccgtcaa tattatattc ctgcacccag
     3121 tatagaagag aatcaatcat atacttgcga aacatttcgt gttcactggc tgtttcattt
     3181 ccaacacccg ttccattctg gaaggtacca tctggattca tacgataata gtaatcaggg
     3241 actgttgttt ggaatggtgc atcaacaact gagaaggtat ggttatagac tacatccata
     3301 atgactccaa tacccgcatc gtgataagct tgaaccatca ccttcaaatc acgaatgacc
     3361 tgagctggat catctggatt agttgaaaaa ctagtttctg gcgcgttata gttttgtgga
     3421 tcataacccc agttgtaggt tacatttcca tcctcatcgt attctttatg acggtctgca
     3481 attggttgca attgaacata attgtagccc agcttcttga tgtaatcaaa agcagttgac
     3541 tggccgtatt ggttaactgt tccagcctga gcagcaccca agaaagttcc tcgaagatgt
     3601 tcatctacac ccgatgtagg tgatttagtc aaatcacgaa tatgcatttc acagataact
     3661 gccttacatg gattttccaa gcgccaagta gcctccgaac cgtgcttaac ctcgaagttt
     3721 tcaacttgct tttctacatg gctcagaata gctgaacgtt tgccatcagg gctggtcgcg
     3781 attgtataag gatcacgtgt cagtgtttgg tgatgaggga attggacttg atactgataa
     3841 gtcttaccta ccaaatcttc ttcaacatcc aaactccaga caccgattgt attgtcctta
     3901 tgattataag agtagctatt gcctcttttc atctcaaaag tcttccaaac gggtgcatca
     3961 ttagcagctg attcataaac gacaacttgc acttctgtcg ctgtaggtga ccagagggaa
     4021 aaatgagcct gattgtcctc tacacggcaa cccaattctc cttggtaacc ccaatgatga
     4081 tcaaaactag cactgttaat ggccttatca aaggcaaaag gattttgatt tttatagaaa
     4141 ggactggcaa tagcaggatt ttcagagtaa taaatcctat catcgccttc caaaatccag
     4201 acctctgtta ataggggata gtgattaaaa cggatagaat attctttact agtttgacct
     4261 gtatgaacca caaaattcaa gctttctata acatgtgaac ttgggtgttc aaagctaaat
     4321 aaagctccaa aataatcttc tttgtaggtt agcaaatcaa ttcgttgatc ctgacttttt
     4381 acaaaggagc aagtgtcata ttctccattc ttacgatggt aatgaatgcg catagggtag
     4441 ttatacattt tttatttttc ctttttactt tgtttctatt tcactaataa atttttgtca
     4501 atctcgtctc aattaacaga catagtcata ttctctaaac tctgttttta aacgatccat
     4561 tacaaacttt ctagccatgc ctcatctctg acctggatac caagttcttg tgctttttgc
     4621 agtttacttc cagcgtctgc acctaccacg acgaggtcgg tctttttaga aacactacct
     4681 gtcactttgg cacccagact ttcgagttta cttttagctt ctgagcgctt gagtcgttcc
     4741 aattttcctg tcaataccac ggtcaaacct gacaaggccg catccgctac taccgtctgt
     4801 cctttatagt ccagattgac cccagtttct ttcaattctc tgagcagaat ttcagagcct
     4861 tctgtcgcaa aataagtctg aagacttttg gcaatcacgc cacctagact ttcaatacta
     4921 gccacttcct ctgaatctgc ctgagacaga ttttcaattg aatggaaata ttgaagtaaa
     4981 agctgactag ccttgcttcc gacatgacga attcccaaac caaataagag cttctcggca
     5041 gaattttcct ttgatgcttg gatagcctga tacagtttag cagcggactt ttccttaacc
     5101 ccctctaaaa ggaggaaatc ctcttcttgc aaacgataaa tatccgccac atccttgact
     5161 aaattagcag caaaaagctt ctcaacaata gatggaccaa ggcctgtaat attcatagca
     5221 tcacgagaag caaagtgaat caagccttcc atgatttgag cagggcaacg cggattgata
     5281 caacgtaggg ccacttcatc ttcaaagtgc aacaagtcag agttacaact tggacagttt
     5341 gtagggatat ctagtttttc ttcagaaacc cgtttggact ctaccacacg taaaacggca
     5401 gggatgatgt caccagcctt atatacaatg accgtatcgt cttttcggat atctttttca
     5461 gcaatataat ctacattgtg cagggtcgca cggctaacag tcgtaccggc aagttgtact
     5521 ggtgttagat tagcagttgg agttacaaca ccggtacggc caactgtcca gtcaactgat
     5581 aagagttgag cttctttttc ttcagcaggg aacttgtagg ctactgccca ctttggagcc
     5641 ttaacggtaa aaccaagttc ttcttgactt gctaggtcgt tgaccttgat taccactcca
     5701 tcaatatcgt aaggcagatt ttcccgttcc tgtcctactt cttggataaa attccagatt
     5761 tcatctatgt tttcagccaa gattcgctta ggattgacca caaaacctag ttgttctagg
     5821 tacttcaaac ccttttcttg gctatcacga gttgaagggc tggcttcttg atagagaaac
     5881 gttgcaagat tacgcttggc aactactgct gtatccaact gacgcagagt tcctgctgcc
     5941 gcattacgag gattagcaaa ttcaggctct ccattttctt ggcgcacttg gttaacttgg
     6001 tcaaaggaag cgcgtggcat gtaacattcc ccacgaactg tgatatctag ttcttctggc
     6061 aaagtcaaag ggatgtcctt aacacgcttg aggttttctg tgatattttc accaattgaa
     6121 ccatctccac gtgttacccc agcaaccaaa atcccctttt cataagtcag cgagatagat
     6181 aagccatcga ttttcagctc acaaatatag gtcggatgag ccacttcctt acgaacacgc
     6241 gcatcaaaag catctagctc ctcacgtgaa aaagcatcct gcaaactata aagaggatac
     6301 tgatgactgt atttttcaaa accatctaaa accttgccac caacacgatg agtcggactg
     6361 tctgctagca cttgctctgg ataagcagtt tctaactcga ccaactcacg gtaaaggcgg
     6421 tcatactcac tgtctgaaac cgagggatta tcgctggtat agtactcagt cgcatagcga
     6481 ttgagcaaag cgactaactc attcattctt ttattcataa gaccatttta ccataaaaca
     6541 agccctcctc acaaacgaga agggcggaaa aaacacttag tttgaaatta tttttgaaac
     6601 tcaagcaacc ttatatcaat ttttcaaaat gagttcgaac ataaataaac gatatacaag
     6661 acaagatgat aacaccactt ccaattatca ggaaagaaga gagatgtaca cttggcaaga
     6721 ctgtcataaa tccttttgca ataggcataa atagaatagc taaggtaaaa attgtactca
     6781 gtactcttcc aagaaattcg ctctcaacct tggtttgtac ttgagtaaaa aagt
//
LOCUS       DAVBBO010000082         6498 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ST1
            SAMEA2066453-rid20184263.denovo.082, whole genome shotgun sequence.
ACCESSION   DAVBBO010000082 DAVBBO010000000
VERSION     DAVBBO010000082.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2066453
            Sequence Read Archive: ERR351777
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 6498)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6498)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980402.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980402.1
            Genome Coverage       :: 176x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:17:33
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,141
            CDSs (total)                      :: 2,104
            Genes (coding)                    :: 1,953
            CDSs (with protein)               :: 1,953
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 16S)
            partial rRNAs                     :: 1 (23S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 151
            CDSs (without protein)            :: 151
            Pseudo Genes (ambiguous residues) :: 0 of 151
            Pseudo Genes (frameshifted)       :: 73 of 151
            Pseudo Genes (incomplete)         :: 76 of 151
            Pseudo Genes (internal stop)      :: 40 of 151
            Pseudo Genes (multiple problems)  :: 32 of 151
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6498
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2066453-rid20184263.denovo.082"
                     /strain="ST1"
                     /db_xref="taxon:1313"
     gene            complement(<1..154)
                     /locus_tag="VQU30_002029"
     CDS             complement(<1..154)
                     /locus_tag="VQU30_002029"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2448069.1"
                     /translation="MSLITHRRFISCNEIIKHYKRLIDKAEKCVNDLMAEFNSVITTV
                     TGIGNRL"
     gene            307..2073
                     /gene="patB"
                     /locus_tag="VQU30_002030"
     CDS             307..2073
                     /gene="patB"
                     /locus_tag="VQU30_002030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000859866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux ABC transporter subunit PatB"
                     /protein_id="HET2448070.1"
                     /translation="MKTVQFFWHYFKVYKFSFVVVILMIVLATFAQALFPVFSGQAVT
                     QLANLVQAYQNGNPELVWQSLSGIMVNLGLLVLVLFISSVIYMCLMTHVIAESTNEMR
                     KGLFGKLAQLTVSFFDRRQDGDILSHFTSDLDNILQAFNESLIQVMSNIVLYIGLILV
                     MFSRNVTLALITIASTPLAFLMLIFIVKMARKYTNLQQKEVGKLNAYMDESISGQKAV
                     IVQGIQEDMMAGFLEQNERVRKATFKGRMFSGILFPVMNGMSLINTAIVIFAGSAVLL
                     NDKSIETSTALGLIVMFAQFSQQYYQPIIQVAASWGSLQLAFTGAERIQEMFDAEEEI
                     RPEKAPTFTKLQESVEISHIDFSYLPDKPILKDVSISAPKGQMTAVVGPTGSGKTTIM
                     NLINRFYDVDAGGIYFDGKDIRGYDLDSLRSKVGIVLQDSVLFSGTIRDNIRFGVPDA
                     SQEMVEVAAKATHIHDYIESLPDKYDTLIDDDQSIFSTGQKQLISIARTLMTDPEVLI
                     LDEATSNVDTVTESKIQHAMEVVVAGRTSFVIAHRLKTILNADQIIVLKDGEVIERGN
                     HHELLKLGGFYSELYHNQFVFE"
     gene            2212..2901
                     /locus_tag="VQU30_002031"
     CDS             2212..2901
                     /locus_tag="VQU30_002031"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466883.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gamma-glutamyl-gamma-aminobutyrate hydrolase
                     family protein"
                     /protein_id="HET2448071.1"
                     /translation="MARTVVGVAANLCPVDAEGKIIHSSVSCRFAEIIRQVGGLPLVI
                     PVGDESVVRDYVEMIDKLILTGGQNVHPQFYGEKKTVESDDYNLVRDEFELALLKEAL
                     RQNKPIMAICRGVQLVNVAFGGTLNQEIEGHWQGLPFGTSHSIETVEGSVVAKLFGKE
                     SQVNSVHRQSIKDLAPNFRVTAIDSRDQTIEAIESIDEHRIIGLQWHPEFLVNEEDGN
                     LELFEYLLDEL"
     gene            2905..3084
                     /locus_tag="VQU30_002032"
     CDS             2905..3084
                     /locus_tag="VQU30_002032"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866816.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2448072.1"
                     /translation="MEHLVVLSFIFSKFLECGILRKRLNSDKNWRNSTKKLEKNEGKR
                     YDRKEEILEEEHVTY"
     gene            3071..4420
                     /locus_tag="VQU30_002033"
     CDS             3071..4420
                     /locus_tag="VQU30_002033"
                     /EC_number="5.3.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399450.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-6-phosphate isomerase"
                     /protein_id="HET2448073.1"
                     /translation="MSHIKFDYSKVLDKFVAPHEVEYMQSQVTAADELIRKGTGAGSD
                     FLGWLDLPEKYDREEFDRILKAAEQIKSDSDVLVVIGIGGSYLGAKAAIDFLNHHFAN
                     LQTKEERKAPQILYAGNSISSTYLADLVEYVADKDFSVNVISKSGTTTEPAIAFRVFK
                     ELLVKKYGQEEANKRIYATTDRQKGAVKVEADANGWGTFVVPDDIGGRFSVLTAVGLL
                     PIAASGADIKALMEGANAARKDYTSDKISENEAYQYAAVRNILYRKGYATEILVNYEP
                     SLQYFSEWWKQLAGESEGKDQKGIYPTSANFSTDLHSLGQFIQEGTRIMFETVVRVDK
                     PRKNVLIPTLEEDLDGLGYLQGKDVDFVNKKATDGVLLAHTDGDVPNMYVTLPEQDAF
                     TLGYTIYFFELAIALSGYLNAINPFDQPGVEAYKRNMFALLGKPGFEELSKELNARL"
     gene            4544..6004
                     /locus_tag="VQU30_002034"
     CDS             4544..6004
                     /locus_tag="VQU30_002034"
                     /EC_number="6.1.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate--tRNA ligase"
                     /protein_id="HET2448074.1"
                     /translation="MSKDIRVRYAPSPTGLLHIGNARTALFNYLYARHHGGTFLIRIE
                     DTDRKRHVEDGERSQLENLRWLGMDWDESPESHENYRQSERLDLYQKYIDQLLAEGKA
                     YKSYVTEEELAAERERQEVAGETPRYINEYLGMSEEEKAAYIAEREAAGIIPTVRLAV
                     NESGIYKWHDMVKGDIEFEGGNIGGDWVIQKKDGYPTYNFAVVIDDHDMQISHVIRGD
                     DHIANTPKQLMVYEALGWEAPEFGHMTLIINSETGKKLSKRDTNTLQFIEDYRKKGYL
                     PEAVFNFIALLGWNPGGEDEIFSREELIKLFDENRLSKSPAAFDQKKLDWMSNDYIKN
                     ADLETIFEMAKPFLEEAGRLTDKAEKLVELYKPQMKSVDEIIPLTDLFFSDFPELTEA
                     EREVMTGETVPTVLEAFKAKLEAMTDDKFVTENIFPQIKAVQKETGIKGKNLFMPIRI
                     AVSGEMHGPELPDTIFLLGREKSIQHIENMLKEISK"
     gene            6018..6452
                     /locus_tag="VQU30_002035"
     CDS             6018..6452
                     /locus_tag="VQU30_002035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytidine deaminase"
                     /protein_id="HET2448075.1"
                     /translation="MDIWEKMYEEAQKLYNPHEVSDFVYANHVVAAVEAEDGQIFTGF
                     CMEGTCGVFHLCAERAALFNTYQFSGQTKVKKVLAFRDKPPYGGSSAMPCGACREFLL
                     ELNAENKDAEFMMDYNIRKTVKVAELIPYWWGEERASKFNER"
BASE COUNT         2036 a         1251 c         1397 g         1814 t
ORIGIN      
        1 ctaaacgatt cccaatccca gtaaccgtcg tgatgaccga gttgaactca gccatcaagt
       61 cattgacaca tttttccgcc ttgtcaatga gcctcttgta atgtttgatg atttcattac
      121 acgagataaa acgtctatgc gttatcaaac tcattaccaa ttaaaacaaa aagctgtggt
      181 tagatccttt cggaaatcgt caagcgattg gaggaaatga actaatccac agcggcttat
      241 tccaagtata ccacttgggc tttggcagta gctaactgcg ctaaatataa tataaggagg
      301 agtaaaatga agacagttca atttttttgg cattatttta aggtctacaa gttctcattt
      361 gtagttgtca tcctgatgat tgttctggcg acttttgccc aagccctctt tccagtcttt
      421 tctggacaag cggtgacgca gctagccaat ttagttcaag cttatcaaaa tggcaatcca
      481 gaacttgtat ggcaaagcct atcaggaatc atggtcaatc ttggcctgct ggttttggtt
      541 ctatttatct ctagtgtaat atacatgtgt ctcatgacgc acgtgattgc agaatcgacc
      601 aacgagatgc gcaaaggcct ctttggtaag cttgctcagt tgacggtttc tttctttgac
      661 cgtcgacaag atggcgatat cttgtctcat tttaccagtg atttggataa tatcctccaa
      721 gcctttaacg aaagcttgat tcaggtcatg agcaatattg ttttatacat tggtctgatt
      781 cttgtcatgt tttcgagaaa tgtgacgctg gctctcatca ccattgccag caccccattg
      841 gctttcctta tgctgatttt catcgtgaaa atggcacgca aatacaccaa cctccagcag
      901 aaagaggtag ggaagctcaa cgcctatatg gatgagagca tctcaggcca aaaagccgtg
      961 attgtgcaag gaattcaaga ggatatgatg gcaggatttc ttgaacaaaa tgagcgcgtg
     1021 cgcaaggcaa cctttaaagg aagaatgttc tcaggaattc ttttccctgt catgaatggg
     1081 atgagcctga ttaatacagc catcgtcatc tttgctggtt cggctgtact tttgaatgat
     1141 aagtctattg aaacaagtac agccctaggt ttgattgtta tgtttgcaca attttcacag
     1201 cagtactacc agcctattat ccaagttgca gcgagttggg gaagccttca gttggccttt
     1261 actggagctg aacgaattca ggaaatgttt gatgcagagg aggaaatccg acctgaaaag
     1321 gctccaacct tcactaagtt gcaagaaagt gttgaaatca gtcatatcga tttttcatac
     1381 ttgcctgata aacctatttt gaaagatgtc agcatttctg cccctaaagg ccagatgaca
     1441 gcagttgttg ggccgacagg ttcaggaaaa acgactatta tgaacctcat caatcgcttt
     1501 tatgatgttg atgctggtgg tatttatttt gatggtaaag acattcgtgg ctatgactta
     1561 gatagtctta gaagcaaggt gggaattgta ttgcaagatt cggtcttgtt tagcggaacg
     1621 attcgagaca atatccgatt tggtgtgcca gatgctagtc aggaaatggt tgaggtagca
     1681 gcaaaagcaa cccacattca cgactatatc gaaagtttgc ctgataagta cgatactctt
     1741 attgatgatg accagagcat cttttcaaca gggcagaagc aattgatttc aatcgctcga
     1801 accctgatga cagatccaga agttctcatt ctcgatgaag caacttcaaa cgtagatacg
     1861 gtgacagaaa gcaagattca gcatgccatg gaggtggttg tagcaggtag aactagtttc
     1921 gtcattgccc accgcttgaa aaccattctc aatgcagatc agattattgt ccttaaagat
     1981 ggagaagtca ttgaacgtgg taaccaccat gaacttttga agctaggtgg cttttattca
     2041 gaactctatc acaatcaatt tgttttcgaa taagaaagaa gttgtcctat gtgggcagct
     2101 ttttcttgtc cataaaaaat gtttatcaca gccttaaaaa aaacatatta gacgaaagtc
     2161 attttgagtg atatgatagg actatcgtta gcattcgaaa ggagaggcat catggctaga
     2221 acggttgtag gagttgctgc aaatctatgt cccgtagacg cagaaggcaa aatcattcat
     2281 tcatctgtat cttgtagatt cgcagagatc attcgtcaag tcggtggtct ccctttagtc
     2341 attcctgttg gtgatgagtc agttgtacgt gattatgtgg aaatgattga caaactcatt
     2401 ttgacaggag gccaaaatgt tcatcctcag ttttatggag agaaaaagac cgtcgagagc
     2461 gatgattaca atctggtccg tgacgaattt gaattggcac tcttgaagga agcgcttcgt
     2521 cagaataaac caattatggc aatctgtcgc ggtgtccaac ttgtcaatgt tgcctttggt
     2581 ggaaccctca atcaagaaat cgaaggtcac tggcaaggac tacctttcgg gacatctcac
     2641 tctattgaga cagtagaagg aagcgtggtg gctaagctat ttgggaaaga aagtcaggtc
     2701 aactcagtcc atcgtcaaag cattaaagat ttggcaccta atttccgtgt aactgctatt
     2761 gattcaagag accaaactat tgaagcgatt gagtctatcg acgagcaccg cattatcggt
     2821 ttacagtggc atccagagtt tctggttaat gaagaagatg gcaatttaga attatttgag
     2881 tatttattgg atgaactgta acaattggaa catctggtcg ttctttcttt tattttttca
     2941 aaatttttag aatgtggtat tttacgcaaa cgtttgaatt ctgataaaaa ttggagaaat
     3001 tcgacaaaaa aacttgaaaa aaacgaaggt aagcgttatg atagaaaaga agaaatattg
     3061 gaggaagaac atgtcacata ttaaatttga ttattcaaaa gttttagaca aatttgttgc
     3121 accacatgaa gtggaataca tgcaatcaca agtaacagca gcagatgaat tgatccgtaa
     3181 aggaactggt gctggtagcg acttcttggg atggttggac cttcctgaaa aatacgaccg
     3241 cgaagaattt gaccgcatct tgaaagctgc tgagcaaatc aagtcagaca gcgatgtttt
     3301 ggttgtgatc ggtattggtg gatcttacct tggtgcaaaa gcagcaatcg acttcttgaa
     3361 tcaccatttt gctaacttgc aaacaaaaga agaacgcaaa gctccacaaa tcctttacgc
     3421 aggaaactca atctcatcta cttaccttgc tgacttggta gagtatgttg cagacaaaga
     3481 cttctcagta aacgtaattt ctaaatcagg tacaacaact gaaccagcga ttgctttccg
     3541 tgtctttaaa gaactcttgg ttaagaaata cggtcaagaa gaagctaaca aacgtatcta
     3601 tgcaacaact gaccgccaaa agggtgctgt taaggttgaa gcagacgcta acggttgggg
     3661 aacatttgtt gttccagatg atatcggtgg acgcttctca gtattgacag ccgttggttt
     3721 gcttccaatc gcagcatcag gagctgacat aaaagctctt atggaaggtg cgaatgcagc
     3781 tcgcaaagac tacacttcag acaaaatctc tgaaaacgaa gcttaccaat acgcagctgt
     3841 tcgtaacatc ctttatcgta aaggctatgc aactgagatc ttggtaaact atgagccatc
     3901 acttcaatac ttctcagaat ggtggaaaca attggctggt gaatcagaag gaaaagacca
     3961 aaaaggtatc tacccaactt cagccaactt ctcaactgac ttgcactcac ttggtcaatt
     4021 tatccaagaa ggaactcgta tcatgtttga aacagttgtc cgtgttgaca aacctcgtaa
     4081 aaacgtgctt attcctactt tggaagaaga ccttgacgga cttggttacc ttcaaggaaa
     4141 agacgttgac tttgtaaaca aaaaagcaac tgacggtgtt cttcttgccc acacagatgg
     4201 tgatgtacca aacatgtatg tgactcttcc agagcaagac gctttcactc ttggttacac
     4261 tatctacttc ttcgaattgg caattgccct ttcaggttac ttgaatgcta tcaacccatt
     4321 tgaccaacca ggtgttgaag cttataaacg taacatgttt gcccttcttg gaaaaccagg
     4381 atttgaagaa ttgagcaaag aacttaacgc acgtctataa tagaagaaaa gagtggtttg
     4441 cccactcttt ttactctctt tatccataga aattggactc agccaagact tgtgatataa
     4501 tatagaaagc aaaaaggcag acgcctagat aataggagaa actatgtcaa aagatatccg
     4561 cgtacgttac gcaccaagtc caacaggact actacacata ggaaatgctc gtacagcatt
     4621 gtttaattac ttgtatgcgc gccatcatgg tggaacattt ctcatccgta tcgaagatac
     4681 tgaccgtaaa cgccatgtcg aggatggtga acgttcacaa cttgaaaacc ttcgctggtt
     4741 aggcatggat tgggatgaaa gtccagaatc acatgagaat tatcgccagt ctgagcgttt
     4801 ggacttgtat caaaaataca tcgaccaact attagctgaa ggaaaagcct acaaatctta
     4861 cgttacagaa gaagagttgg cagctgaacg tgaacgtcaa gaagtagctg gcgaaacacc
     4921 acgctacatc aatgaatacc ttggtatgag tgaagaagaa aaagcagctt acatcgcaga
     4981 acgtgaagca gcagggatca tcccaactgt tcgtttggct gtcaatgagt caggtatcta
     5041 caagtggcat gatatggtca aaggcgatat cgaatttgaa ggtggcaata tcggtggtga
     5101 ctgggttatc caaaagaaag acggttaccc aacttacaac tttgccgttg ttatcgatga
     5161 ccacgatatg caaatctctc atgttatccg tggagatgac catattgcta atacaccaaa
     5221 acagcttatg gtctatgaag ctcttggttg ggaagctcca gagttcggtc acatgacctt
     5281 gattatcaac tctgagactg gtaagaagtt atctaaacgt gatactaata cacttcaatt
     5341 tatcgaagat taccgaaaga aaggttacct tccagaagca gtctttaatt ttattgctct
     5401 tcttggttgg aacccaggtg gtgaagatga gattttctct cgtgaagaac tcattaaact
     5461 ttttgatgaa aaccgcctca gcaagtcacc agcagccttt gatcagaaaa aactagactg
     5521 gatgagcaat gattatatca agaatgcaga ccttgaaacc atctttgaaa tggcaaaacc
     5581 attcttagag gaagcaggcc gtttgactga caaggctgaa aaattagttg agctctataa
     5641 accacaaatg aaatcagtag atgagattat cccattgaca gatcttttct tctcagattt
     5701 cccagaattg acagaagcag agcgcgaagt catgacgggt gaaacagttc caacagttct
     5761 tgaagcattc aaagcaaaac ttgaagcgat gacagatgat aaatttgtga cagaaaatat
     5821 cttcccacaa attaaagcag ttcaaaaaga aacaggtatt aaagggaaaa atcttttcat
     5881 gcctattcgt atcgcagttt caggcgaaat gcatgggcca gaattaccag atacaatttt
     5941 cttgcttgga cgtgaaaaat caattcagca tatcgaaaac atgctaaaag aaatctctaa
     6001 ataaagagga tacaataatg gacatctggg aaaagatgta cgaagaagca cagaaactat
     6061 acaatccaca tgaagtatca gactttgttt atgccaatca tgttgtagct gcagtagaag
     6121 cagaagatgg acaaatattt acaggattct gtatggaggg aacctgtggt gttttccatc
     6181 tctgcgcaga acgggcggcc ctcttcaata cgtaccaatt ttcaggacaa actaaggtta
     6241 agaaagtatt agcctttcga gacaaaccac cttatggtgg aagttcagcc atgccttgcg
     6301 gtgcttgtag agaattcctt ttagagctta atgctgaaaa taaagatgca gaattcatga
     6361 tggactataa tataagaaaa acagttaaag tcgcagaact aatcccttat tggtggggag
     6421 aagaacgtgc ttctaagttt aatgagcgat agaagagtca gtataattct ggcttttttt
     6481 actataagtt gaaaaaat
//
LOCUS       DAVBBO010000083         6447 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ST1
            SAMEA2066453-rid20184263.denovo.083, whole genome shotgun sequence.
ACCESSION   DAVBBO010000083 DAVBBO010000000
VERSION     DAVBBO010000083.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2066453
            Sequence Read Archive: ERR351777
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 6447)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6447)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980402.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980402.1
            Genome Coverage       :: 176x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:17:33
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,141
            CDSs (total)                      :: 2,104
            Genes (coding)                    :: 1,953
            CDSs (with protein)               :: 1,953
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 16S)
            partial rRNAs                     :: 1 (23S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 151
            CDSs (without protein)            :: 151
            Pseudo Genes (ambiguous residues) :: 0 of 151
            Pseudo Genes (frameshifted)       :: 73 of 151
            Pseudo Genes (incomplete)         :: 76 of 151
            Pseudo Genes (internal stop)      :: 40 of 151
            Pseudo Genes (multiple problems)  :: 32 of 151
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6447
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2066453-rid20184263.denovo.083"
                     /strain="ST1"
                     /db_xref="taxon:1313"
     gene            222..422
                     /locus_tag="VQU30_002036"
     CDS             222..422
                     /locus_tag="VQU30_002036"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000226586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2448076.1"
                     /translation="MVASASASSTSTQAQEQVDKSELRALSQELDQRLKALATVSDPK
                     IDATKAVLLDAQKAPEDSALTE"
     gene            447..863
                     /locus_tag="VQU30_002037"
     CDS             447..863
                     /locus_tag="VQU30_002037"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000642281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2448077.1"
                     /translation="MKAALDSLKDVKANASDSKPAQDKKDAKQGTEDSKDSDKMTETN
                     SVPAGVIVVSLLALLGVIAFWLIRRKKESEIQQLSTELIKVLGQLDAEKADKKVLAKA
                     QNLLQETLDFVKEENGSAETETKLVEELKAILDKLK"
     gene            1094..1801
                     /gene="ccdA2"
                     /locus_tag="VQU30_002038"
     CDS             1094..1801
                     /gene="ccdA2"
                     /locus_tag="VQU30_002038"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004237834.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiol-disulfide oxidoreductase-associated
                     membrane protein CcdA2"
                     /protein_id="HET2448078.1"
                     /translation="METIVFLISVFLAGVLSFFSPCIFPLLPVYAGILLDDQESAKSF
                     SLFGRKVLWSGLIRTLCFIAGISLIFFILGFGAGYFGHILYANWFRYVMGAIIIILGL
                     HQMEIFHLKKLEVQKSFTFKKSDSNRYWSAFLLGITFSFGWTPCIGPVLSSVLALAAS
                     GGNGAWQGAIYTLIYTLGMALPFLVLALASGLVMPYFSKIKRHMMLLKKIGGFLIVLM
                     GILLLLGQVNVLAGIFE"
     gene            1812..2369
                     /gene="sdbB"
                     /locus_tag="VQU30_002039"
     CDS             1812..2369
                     /gene="sdbB"
                     /locus_tag="VQU30_002039"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000757364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiol-disulfide oxidoreductase-associated
                     lipoprotein SdbB"
                     /protein_id="HET2448079.1"
                     /translation="MKKVMFAGLSLLSLVVLMACGEEETKKTQAAQQPKQQTTVQQIA
                     VGKDAPDFTLQSMDGKEVKLSDFKGKKVYLKFWASWCGPCKKSMPELMELAAKPDRDF
                     EILTVIAPGIQGEKTVEQFPQWFQEQGYKDIPVLYDTKATTFQAYQIRSIPTEYLIDS
                     QGKIGKIQFGAISNADAEAAFKEMN"
     gene            2490..3881
                     /locus_tag="VQU30_002040"
     CDS             2490..3881
                     /locus_tag="VQU30_002040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001020339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HET2448080.1"
                     /translation="MNIFRTKNVSLDKTEMHRHLKLWDLILLGIGAMVGTGVFTITGT
                     AAATLAGPALVISIVISALCVGLSALFFAEFASRVPATGGAYSYLYAILGEFPSWLAG
                     WLTMMEFMTAISGVASGWAAYFKGLLSQYGIAFPQALNGTFNPQAGTFVDLLPILVLV
                     LVTSLVLLNAKAALRFNSILVILKFSALALFVLVGIWNIKFDNWSNFAPYGFGQIYGA
                     STGIMAGASLMFFGFLGFESISMAVDEVKTPQKNIPRGIVLSLSIVTILYALVTLVLT
                     GVVHYSHLNVDDAVAFALRSVGISWAANYVSLVAILTLITVCISMTYALSRMIYSLAR
                     DGLVPAAFKELTKTSKIPKNATILTGLASAVAAGMFPLASIAAFLNICTLAYLIMLAY
                     GLIRLRKEKGMPKAGEFKTPLVPLLPILSIIICLSFMLQYNMNTWIAFLVALLVGSII
                     YFTYGYKHSTIEE"
     gene            4024..4941
                     /gene="adcAII"
                     /locus_tag="VQU30_002041"
     CDS             4024..4941
                     /gene="adcAII"
                     /locus_tag="VQU30_002041"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000744528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc-binding lipoprotein AdcAII"
                     /protein_id="HET2448081.1"
                     /translation="MKKQNLFLVLLSVFLLCLGACGQKESQTGKGMKIVTSFYPIYAM
                     VKEVSGDLNDVRMIQSSSGIHSFEPSANDIAAIYDADVFVYHSHTLESWAGSLDPNLK
                     KSKVKVLEASEGMTLERVPGLEDVEAGDGVDEKTLYDPHTWLDPEKAGEEAQIIADKL
                     SEVDSEHKETYQKNAQAFIKKAQELTKKFQPKFEKATQKTFVTQHTAFSYLAKRFGLN
                     QLGIAGISPEQEPSPRQLTEIQEFVKTYKVKTIFTESNASSKVAETLVKSTGVGLKTL
                     NPLESDPQNDKTYLENLEENMSILAEELK"
     gene            4949..>6447
                     /locus_tag="VQU30_002042"
     CDS             4949..>6447
                     /locus_tag="VQU30_002042"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000700331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pneumococcal-type histidine triad protein"
                     /protein_id="HET2448082.1"
                     /translation="MKINKKYLAGSVAVLALSVCSYELGRHQAGQVKKESNRVSYIDG
                     DQAGQKAENLTPDEVSKREGINAEQIVIKITDQGYVTSHGDHYHYYNGKVPYDAIISE
                     ELLMKDPNYQLKDSDIVNEIKGGYVIKVDGKYYVYLKDAAHADNIRTKEEIKRQKQER
                     SHNHNSRADNAVAAARAQGRYTTDDGYIFNASDIIEDTGDAYIVPHGNHFHYIPKSDL
                     SASELAAAQAYWNGKQGSRPSSSSSHNANPAQPRLSENHNLTVTPTYHQNQGENISSL
                     LRELYAKPLSERHVESDGLVFDPAQITYRTVNGVAVPHGDHYHFIPYSQLSPLEEKLA
                     RMIAVKGQNGAVLPGMHYLKPAPKPQVQPSTEKKQTDFAVEQVVRKVGEGYVVEIAGV
                     SHYVFAKDLAKDKIDAIENLLSKKTQETHALVAKKENVAPRDQEFYDKAYNLLTQAHK
                     VLSENKGRTSDFQALDKLAERLNNESSNKVKLVDDLLAFLAPITHPERLG"
BASE COUNT         1980 a         1172 c         1354 g         1941 t
ORIGIN      
        1 atggtttcag aaatttctct taccaacatt aaccacacca tcggttatta tagtaaaatg
       61 gaataagaac aggacaaatc gatcaggaca gtaaaatcga attctaacaa tgttttagaa
      121 gtctatatgt actattctag tttcaatata ccataactgc tcctagtcaa cctgcaagtc
      181 ctgtcccagc tccaagctca gctccgactc aagatcctag agtggtagca agcgcttcgg
      241 ctagctcaac gagcacacaa gctcaagagc aagttgacaa gtctgaactt cgtgccttga
      301 gtcaagagtt agaccaacgc ttgaaagctt tggcaacagt atctgatcca aaaatcgatg
      361 caaccaaggc tgtcctccta gatgctcaaa aagctccgga agatagtgcc ttgacagagt
      421 aaggtctgca tactgcagta gagtctgtga aggctgcctt ggactctctc aaagatgtga
      481 aagcaaatgc tagcgacagc aagcctgcac aggacaagaa ggatgcaaaa caaggaacgg
      541 aagatagtaa ggattcagat aagatgactg aaacaaactc agttccggca ggagtgattg
      601 tggtcagtct acttgccctc ctaggcgtga ttgccttctg gctgattcgc cgtaagaaag
      661 agtcagaaat ccagcaatta agcacggaat tgatcaaggt tctaggacag ctagatgcag
      721 aaaaagcgga taaaaaagtc cttgccaaag cccaaaacct tctccaagaa acccttgatt
      781 tcgtgaaaga agaaaatggc tcagcagaga cagaaactaa actagtagag gagcttaaag
      841 caatccttga caaactcaag taaaacatga tttatgaaat gtcagaccta aaagacattt
      901 tcgttcacaa aagcagtgac gagtaatcct tgtcgttgct ttttggctat tttgggggat
      961 aagatccgcc ttgactagca aaagaaaaga ttggtccaat agtgcccgat acgattttgc
     1021 gtagcagaaa gcttacaaat aaaattgaat atagtaaaat aggattagaa ttattaagaa
     1081 agttggttct ttattggaaa cgatagtatt tttaatctct gtttttctag caggtgtttt
     1141 atcctttttt tctccttgta tttttcctct tctgccagtc tatgctggga ttttattgga
     1201 tgatcaagaa agtgcaaaaa gcttttcttt gtttgggaga aaggttctct ggtcaggctt
     1261 gattcgaaca ctttgcttta tcgctggtat ctctctcatt ttctttattc taggctttgg
     1321 tgctggttac tttggtcata ttctctatgc aaattggttt cgatatgtca tgggagctat
     1381 tattatcatt ttgggtcttc accagatgga aatttttcat ttgaagaaat tagaagttca
     1441 aaaaagtttt acctttaaaa aatcagattc taatcgttat tggtcagctt ttttacttgg
     1501 tattaccttt agctttggtt ggacaccttg tattggtcca gttttaagtt ctgttttagc
     1561 acttgcggct tctggaggca atggtgcttg gcaaggagcg atttatactc tcatttacac
     1621 tctgggcatg gcccttcctt tcttggtctt ggcactagct tcaggtctag tcatgccata
     1681 ttttagtaaa atcaagcgtc atatgatgct actaaagaaa attggtggtt tcctcattgt
     1741 tttaatggga attttgttac tattaggaca agtaaatgtt ctagctggaa tttttgaata
     1801 aaggaggaca aatgaaaaaa gtaatgtttg ctggcttaag tctcttgtca ttagttgtat
     1861 tgatggcctg tggtgaggaa gaaactaaaa agactcaagc agcacaacag ccaaaacaac
     1921 aaacgactgt acaacaaatt gctgttggaa aagatgctcc agacttcaca ttgcaatcca
     1981 tggatggcaa agaagttaag ttatctgatt ttaagggtaa aaaggtttac ttgaagtttt
     2041 gggcttcatg gtgtggtcca tgcaagaaaa gtatgccaga gttgatggaa ctagcggcga
     2101 aaccagatcg tgatttcgaa attcttactg tcattgcacc aggaattcaa ggtgaaaaaa
     2161 ctgttgagca attcccacaa tggttccagg aacaaggata taaggatatc ccagttcttt
     2221 atgataccaa agcaaccacc ttccaagctt atcaaattcg aagcattcct acagaatatt
     2281 taattgatag ccaaggaaag attggaaaga ttcaatttgg tgctatcagt aatgcggatg
     2341 cagaagcagc atttaaagaa atgaactaga atcgataaaa tctgattaca agatgtagtc
     2401 agattttttt agaaaaacat tttataaata ttcacatatc tcctatattt atggtaaaat
     2461 agaattatca gtttattttg gagtcaaaga tgaatatatt tagaacaaag aatgttagtt
     2521 tagataaaac agagatgcat aggcatttga agttatggga tttgattttg ctgggtatcg
     2581 gagccatggt agggacaggc gtctttacaa tcacaggtac tgcagctgca acacttgctg
     2641 gcccagccct agtgatttca atcgttattt ctgccttgtg tgtgggatta tcagccctct
     2701 tttttgcaga atttgcctcg cgagtacccg ctacaggagg tgcctatagt tacctctatg
     2761 ctatcttagg agaattccct tcctggttgg ctggttggtt aaccatgatg gagttcatga
     2821 cagccatatc aggcgtagct tcgggttggg cagcttattt taaaggcttg ctctctcaat
     2881 acgggatagc ctttcctcag gctttaaatg gtacctttaa tcctcaagca gggacatttg
     2941 ttgatttatt gcctattctt gtcttggtct tggtgacttc gcttgtttta ctaaatgcca
     3001 aggcagcctt acgctttaat tcgattctag ttattttgaa attttccgct ttagctctct
     3061 ttgttttagt aggaatttgg aatattaagt ttgataattg gagcaatttt gctccttacg
     3121 gttttggaca aatctatgga gctagcactg gtattatggc tggtgcgtcc ttgatgttct
     3181 tcggtttttt gggatttgaa tccatctcta tggctgtaga tgaagtcaag actcctcaaa
     3241 aaaatattcc tagagggatt gtcttatcgc tttctatcgt aaccattctc tatgccttgg
     3301 tgacccttgt tttgactggt gtggttcact atagtcattt aaatgtcgat gatgccgttg
     3361 cctttgccct tcgtagtgtt gggattagtt gggcagccaa ctatgtgtca ttagtggcta
     3421 tcttgacctt gattacagtt tgtatttcga tgacctatgc cctatcgcgt atgatttaca
     3481 gtttagcacg tgacggctta gtgcctgctg cctttaagga actgacgaag actagcaaga
     3541 taccaaagaa tgctactatc ttgacaggtc tagcttcagc agtagcagca ggaatgttcc
     3601 cactagccag tattgcagcc tttttaaata tttgtacctt agcctacttg atcatgctgg
     3661 cttatggtct gattcgctta cggaaagaaa aaggaatgcc caaagctggg gaatttaaaa
     3721 caccattggt acctctgtta ccaattttat cgatcatcat ttgtttatcc ttcatgttac
     3781 agtataatat gaacacctgg attgctttcc tagttgcgtt gttagtagga agtattattt
     3841 acttcactta tggctataag cattctacca tagaagaata aagtgaaagt ctattgagtt
     3901 gttgacactc agtagatttt tatatgtgaa agaaatttca aattttttct aaaaatatct
     3961 tgacagatta aattttcagg agtagaatat ttactagtta attaaatggt taaggagttg
     4021 ttcatgaaga aacaaaattt atttttagtc ctgttaagtg tctttctttt gtgtttgggg
     4081 gcttgtggtc aaaaggaaag tcagacagga aaggggatga aaattgtgac cagtttttat
     4141 cctatctacg ctatggttaa ggaagtatct ggtgacttga atgatgttcg gatgattcag
     4201 tcaagtagtg ggattcactc ctttgaacct tcggcaaatg atatcgcagc catctatgat
     4261 gcagatgtct ttgtttacca ttctcataca ctcgaatctt gggcaggaag tctggatcca
     4321 aatctaaaaa aatccaaagt gaaggtctta gaggcttctg agggaatgac cttggaacgt
     4381 gtccctggac tagaggatgt ggaagcaggg gatggagttg atgaaaaaac gctctatgac
     4441 cctcacacat ggctagatcc tgaaaaagct ggagaagaag cccaaattat cgctgataaa
     4501 ctttcagagg tggatagtga gcataaagag acttatcaaa aaaatgcgca agcctttatc
     4561 aaaaaagctc aggaattgac taagaaattc caaccaaaat ttgaaaaagc gactcagaaa
     4621 acatttgtaa cacaacatac agccttttct tatctagcga agagatttgg gcttaatcaa
     4681 cttggtattg caggtatctc tcctgaacaa gaaccaagtc cacgacaact aacagaaatt
     4741 caggaatttg ttaagaccta taaggttaaa acgattttta cagaaagtaa cgcttcttca
     4801 aaagtagctg aaactcttgt caaatcaaca ggtgtgggtc ttaaaactct gaatccttta
     4861 gagtcagacc cacaaaatga caagacctat ttagaaaatc ttgaagaaaa tatgagtatt
     4921 ctagcagaag aattaaagtg aggaaagaat gaaaatcaat aaaaaatatc tagcaggttc
     4981 agtggcagtc cttgccctaa gtgtttgttc ctatgaactt ggtcgtcacc aagctggtca
     5041 ggttaagaaa gagtctaatc gagtttctta tatagatggt gatcaggctg gtcaaaaggc
     5101 agaaaatttg acaccagatg aagtcagtaa gagagagggg atcaacgccg aacaaattgt
     5161 tatcaagatt acggatcaag gttatgtgac ctctcatgga gaccattatc attactataa
     5221 tggcaaggtt ccttatgatg ccatcatcag tgaagaactt ctcatgaaag atccgaatta
     5281 tcagttgaag gattcagaca ttgtcaatga aatcaagggt ggctatgtga ttaaggtaga
     5341 cggaaaatac tatgtttacc ttaaagatgc agcccatgcg gacaatattc ggacaaaaga
     5401 agagattaaa cgtcagaagc aggaacgcag tcataatcac aactcaagag cagataatgc
     5461 tgttgctgca gccagagccc aaggacgtta tacaacggat gatgggtata tcttcaatgc
     5521 atctgatatc attgaggaca cgggtgatgc ttatattgtc cctcacggca atcacttcca
     5581 ctatattcct aagagtgatt tgtctgccag tgaattagct gctgcccaag cctattggaa
     5641 tgggaagcag ggatctcgtc cttcttcaag ttctagtcat aatgcaaatc cagctcaacc
     5701 aagattgtca gagaaccaca atctgactgt cactccaact tatcatcaaa atcaagggga
     5761 aaacatttca agccttttac gtgaattgta tgctaaaccc ttatcagaac gccatgtaga
     5821 atctgatggc ctagtatttg atccggcaca aataacatat cgtacagtca atggtgttgc
     5881 tgtaccgcac ggagaccatt atcactttat tccttattca caactgtcac ctttggaaga
     5941 aaaattggct cgtatgattg ctgttaaggg acaaaatggt gcagtcttgc caggaatgca
     6001 ttatttgaaa ccagcaccaa aaccgcaagt tcaaccatca actgagaaaa aacaaactga
     6061 ttttgcagta gaacaggttg ttagaaaagt tggagaaggc tatgttgtgg aaattgctgg
     6121 tgtcagtcac tatgtttttg ctaaagactt ggctaaggat aagattgatg ctattgaaaa
     6181 tctcttgtct aagaaaactc aagagacaca tgctctagtt gctaaaaaag aaaatgtcgc
     6241 tcctcgtgac caagaatttt atgataaagc ttacaatctg ttaacccagg ctcataaagt
     6301 cttgtctgaa aataaaggtc gtacttctga tttccaagcc ttagacaaat tagcagaacg
     6361 cttgaataat gaatcttcta ataaagtaaa attggtagat gatttattgg cattcctagc
     6421 accaattacc cacccagaac gccttgg
//
LOCUS       DAVBBO010000084         4871 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ST1
            SAMEA2066453-rid20184263.denovo.084, whole genome shotgun sequence.
ACCESSION   DAVBBO010000084 DAVBBO010000000
VERSION     DAVBBO010000084.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2066453
            Sequence Read Archive: ERR351777
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 4871)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4871)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980402.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980402.1
            Genome Coverage       :: 176x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:17:33
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,141
            CDSs (total)                      :: 2,104
            Genes (coding)                    :: 1,953
            CDSs (with protein)               :: 1,953
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 16S)
            partial rRNAs                     :: 1 (23S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 151
            CDSs (without protein)            :: 151
            Pseudo Genes (ambiguous residues) :: 0 of 151
            Pseudo Genes (frameshifted)       :: 73 of 151
            Pseudo Genes (incomplete)         :: 76 of 151
            Pseudo Genes (internal stop)      :: 40 of 151
            Pseudo Genes (multiple problems)  :: 32 of 151
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4871
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2066453-rid20184263.denovo.084"
                     /strain="ST1"
                     /db_xref="taxon:1313"
     gene            191..409
                     /locus_tag="VQU30_002043"
     CDS             191..409
                     /locus_tag="VQU30_002043"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001859328.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein-export chaperone SecB"
                     /protein_id="HET2448083.1"
                     /translation="MKKISVTVIGYFEINIDENITDILYVNGTAILYHYLRSIVSIVS
                     AIDSSEAMLLPTINVLELLDKSQPFEEE"
     gene            1454..2446
                     /locus_tag="VQU30_002044"
     CDS             1454..2446
                     /locus_tag="VQU30_002044"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018371202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HET2448084.1"
                     /translation="MAMIEVEHLQKNFVKTVKEPGLKGALRSFIHPEKQTFEAVKDLT
                     FEVPKGQILGFIGANGAGKSTTIKMLTGILKPTSGFCRINGKIPQDNRQDYVKDIGVV
                     FGQRTQLWWDLALQETYTVLKEIYDVPDSLFHKRMDFLNEVLDLKDFIKDPVRTLSLG
                     QRMRADIAASLLHNPKVLFLDEPTIGLDVSVKDNIRRAITQINQEEETTILLTTHDLS
                     DIEQLCDRIFMIDKGQEIFDGTVSQLKETFGKMKTLSFELLPGQSHLVSHYDGLSDMT
                     IDRQGNSLNIEFDSSRYQSADIIKQTLSDFEIRDLKMVDTDIEDIIRRFYRKEL"
     gene            2448..3266
                     /locus_tag="VQU30_002045"
     CDS             2448..3266
                     /locus_tag="VQU30_002045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000240175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-2 family transporter protein"
                     /protein_id="HET2448085.1"
                     /translation="MIKLWRRYKPFINAGVQELITYRVNFILYRIGDVMGAFVAFYLW
                     KAVFDSSQESLIQGFSMADITLYIIMSFVTNLLTRSDSSFMIGEEVKDGSIIMRLLRP
                     VHFAASYLFTELGSKWLIFISVGLPFLSVIVLMKIISGQGIVEVLGLTVIYLFSLTLA
                     YLINFFFNICFGFSAFVFKNLWGSNLLKTSIVAFMSGSLIPLAFFPKVVSDILSFLPF
                     SSLIYTPVMIIVGKYDASQILQALLLQFFWLLVMVGLSQLIWKRVQSFITIQGG"
     gene            3268..4053
                     /locus_tag="VQU30_002046"
     CDS             3268..4053
                     /locus_tag="VQU30_002046"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003010202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HET2448086.1"
                     /translation="MKKYQRMHLIFIRQYIKQIMEYKVDFVVGVLGVFLAQGLNLLFL
                     NVIFQHIPFLEGWTFQEIAFIYGFSLIPKGMDHLFFDNLWALGQRLVRKGEFDKYLTR
                     PINPLFHILVETFQIDALGELLVGGILLGTTVTSIVWTLPKFLLFLVCIPFATLIYTS
                     LKIATASIAFWTKQSGAMIYIFYMFNDFAKYPISIYNSLLRWLISFIVPFAFTAYYPA
                     SYFLQEKDVFFNVGGLMLISLVFFVISLKLWDKGLDSYESAGS"
     gene            4092..4370
                     /locus_tag="VQU30_002047"
     CDS             4092..4370
                     /locus_tag="VQU30_002047"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001808742.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family acetyltransferase"
                     /protein_id="HET2448087.1"
                     /translation="MFVIEEVKDENQKKAVVAEVLKDLPEWFGIPESTQAYIEGTTTL
                     QVWTAYQESDLTRFVSLSYSSEDCAEIDCLGVKKLIKVEKLGANCLLL"
     gene            4355..4552
                     /locus_tag="VQU30_002048"
     CDS             4355..4552
                     /locus_tag="VQU30_002048"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012512706.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HET2448088.1"
                     /translation="MLATLESEARKKVGYLQVKTVAEGSNKDYDRTNDFYRGLGFKKL
                     EIFPQLWNPQNPCQILIKKLE"
BASE COUNT         1399 a          796 c         1022 g         1654 t
ORIGIN      
        1 ggctagtttc ctagtttgct ctttggtttt catttagtat aacagattgt tagaagttgg
       61 tttaaatttc ctaatcagtt tgttcacatt taccttcgat atattatatc ccatagttaa
      121 ggttggtcat acagatgatt atagtcatgg agccgtaaaa cttagtgttt ctttagttga
      181 caaagatgcc atgaaaaaaa tatctgtaac tgtaatagga tattttgaaa taaatataga
      241 tgaaaatatc accgatattc tatacgtaaa tggtactgct attctttatc attatttacg
      301 ttctattgtt tcaatagttt cggcaattga tagcagtgaa gcaatgttgc tacctaccat
      361 taatgtttta gagttactag ataaatctca accttttgaa gaagaataat ttattagctc
      421 actaaattga gggtaaggaa aagtaaaatc agtaagaaaa atgtcttgca ttatacagca
      481 accttttggg aatgagtaga tggattgaat aaaattttat taagagtgga tgatttatct
      541 gtagattatt attggacagt tagtcttgaa gtagtctaag aattaggtta taatcagtag
      601 aatccttgct aataatgagg aggttagttt atgtatagta gactgaatct aaaatagtac
      661 gaaacaattg ctaaaacatt tatagaaatt aattttactt tcccaatcga tttgttctca
      721 tcttatttca atccgctata tattatggta tcgaatcttc atcagaatga taaaattaat
      781 caattgatat ctgattacaa acagaatatg aaagcttttt atatcactat tgaaaaattt
      841 atacgagatg atgaaagcct taagtgttat tttataaagg ttatttcaag tcgttccaag
      901 gtaacaagtc tagatcagat tgaagctgat aaaacgatac aaagaaaata ttcaagtgag
      961 ctaaaaaaat ttattggatt ttataatgag attatttgtg aggaaaatag tttcctacat
     1021 gtacgaaaga ggtggtcgag ttggtttagg tagtcgatgc gtgagttgat aattctcagg
     1081 gtatggactt ctttttcatg aatgaggtaa aagagcaggt attgtttaga gacaatcatt
     1141 ctgagcatat tttctggata gagggagtat ccgattttat gatcaaagtt aataccgccc
     1201 tctggtgaga agatgagtag gttggtaatt taaactatta aacagaattt ttgattaaaa
     1261 gtattatttt atgagagaaa tcctaatttc acaatccata ggcaaactct tgcatttcgt
     1321 tttttattgg actataatag gttggtataa agccttttgt agtaataaaa tgtagaaggt
     1381 gtagaaagca aggatttaga atatttgtag ttaaaaacac aatgttgcta ttccttacga
     1441 tagggagata gatatggcaa tgatagaagt ggaacatctt cagaaaaatt ttgtgaagac
     1501 tgttaaggaa ccgggcttga agggggcttt gcgctccttt attcatcctg aaaagcagac
     1561 ctttgaagcg gtcaaggatt tgacctttga ggttccaaaa gggcagattt taggatttat
     1621 cggggcaaat ggtgctggga agtcgacaac cattaaaatg ctgacaggaa ttttgaaacc
     1681 aacatctggt ttttgtcgga ttaacggcaa gattccccag gacaatcggc aagattatgt
     1741 caaagatatt ggcgtagtct ttggacaacg cacccagcta tggtgggatt tggctctgca
     1801 agagacctac actgtcttaa aagagattta tgatgtgcca gactcgctct ttcataagcg
     1861 tatggacttt ttgaatgaag tcttggattt gaaggacttt atcaaggatc ccgtgcggac
     1921 tctttcactg ggacaacgga tgcgggcgga tattgcggcc tccttgctcc acaatcccaa
     1981 ggttcttttt ttagatgagc cgaccattgg tttggacgtt tcggttaagg ataatattcg
     2041 tcgggcaatt actcagatca atcaagagga agaaactacc attcttttga ccactcacga
     2101 tttgagtgat attgagcaac tttgtgatcg gattttcatg attgacaagg ggcaagagat
     2161 ttttgatgga acggtgagcc aactcaagga gacctttggt aagatgaaga ctctctcttt
     2221 tgaactgcta ccaggtcaaa gtcatctcgt ctctcactat gacggtctgt ctgatatgac
     2281 cattgataga caaggaaaca gcctcaacat tgaatttgat agttctcgct accagtcagc
     2341 tgacattatc aagcaaaccc tgtctgattt tgaaatccgc gatttgaaga tggtggatac
     2401 ggatattgag gatattatcc gtcgcttcta ccgaaaggag ctctaggatg atcaaattgt
     2461 ggagacgtta taaacccttt atcaatgcag gggttcagga gttgattact taccgagtca
     2521 actttattct ctatcggatt ggcgatgtca tgggggcttt tgtggccttt tatctctgga
     2581 aggctgtctt tgattcttcg caagagtctt tgattcaggg cttcagtatg gcggatatca
     2641 ccctctacat catcatgagt tttgtgacca atcttctgac tagatccgat tcgtccttta
     2701 tgattgggga ggaggtcaag gatggctcca ttatcatgcg tttgttgcga ccagtgcatt
     2761 ttgcggcctc ctatcttttc accgagcttg gttccaagtg gttgattttt atcagcgttg
     2821 gccttccatt tttaagtgtc attgtcttga tgaaaatcat atcgggtcaa ggtattgtag
     2881 aggtgctagg attaactgtc atttatcttt ttagcttaac gctcgcctat ctgattaact
     2941 ttttctttaa tatttgcttt ggattttcag cctttgtgtt taaaaatctt tggggttcca
     3001 acctacttaa gacttccata gtggctttta tgtcggggag tttgattccc ttggcattct
     3061 ttccaaaggt tgtttcagat attctctcct ttttgccttt ttcatccttg atttatactc
     3121 cagttatgat cattgttgga aaatacgatg ccagtcagat tcttcaggca ctccttttgc
     3181 agttcttctg gctcttagtg atggtgggat tgtctcagtt gatttggaaa cgggtccagt
     3241 cctttatcac cattcaagga ggttagtatg aaaaaatatc aacgaatgca tctgattttt
     3301 atcagacaat acatcaaaca aatcatggaa tataaggtgg attttgtggt tggtgtcttg
     3361 ggagtctttc tggctcaagg cttgaatctc ttgtttctca atgtcatctt tcaacatatt
     3421 ccattcctag aaggctggac ctttcaagag atagctttca tttatggatt ttccttgatt
     3481 cccaagggaa tggaccatct cttttttgac aatctctggg cactagggca acgcctagtc
     3541 cgaaaagggg agtttgacaa gtatctgact cgtcccatca atcctctctt tcacatccta
     3601 gttgaaacct ttcagattga tgccttgggt gaactcttag tcggtggtat tttattggga
     3661 acaacagtga ccagcattgt ttggactctt ccgaaattcc tgcttttcct agtttgtatt
     3721 ccttttgcga ccttgattta tacttctctt aaaatcgcaa cagccagtat cgccttttgg
     3781 actaagcagt caggcgccat gatttacatc ttctatatgt tcaatgactt tgctaagtat
     3841 ccgatttcta tttacaattc tcttcttcgt tggttgatta gctttatcgt gcctttcgcc
     3901 tttacagcct actatccagc tagctatttc ttacaggaaa aggatgtgtt ctttaacgta
     3961 ggaggtttga tgttgatttc tctggttttc tttgttattt cccttaaact ttgggataag
     4021 ggcttagatt cctacgaaag tgcgggttcg taaaagctaa agtaagacta aaatcaagaa
     4081 agaaacttat gatgtttgta attgaagaag tcaaggatga aaatcaaaaa aaggcagttg
     4141 tagctgaggt tttgaaggat ttgccagaat ggtttggaat cccagaaagc acacaagcct
     4201 atatagaagg aaccacgaca ctgcaagttt ggaccgccta tcaggagagt gatttgacta
     4261 gatttgtaag cttatcctat tcgagtgaag attgtgcaga gattgattgt ctcggcgtaa
     4321 aaaagcttat caaggtagaa aaattgggag ccaattgctt gctactttag agagtgaagc
     4381 tcgtaaaaaa gttggttatc tgcaggtcaa aacagtggca gaaggttcta ataaagatta
     4441 tgatcgaaca aatgactttt atcgaggtct tggctttaaa aagttagaga tttttcctca
     4501 actatggaat ccgcaaaatc cttgtcagat tttgattaaa aagcttgaat aatattactt
     4561 gacatctatt ctcagagtgc catactgtaa gtgtaatcgc cgatttagct cagttggtag
     4621 agcaaggcac tcgtaaagcc taggttatag gtagataaac gactgaggag ttgaaaaaat
     4681 agataggtag aagataaccg ttaagcctta ttcttagcgg ttatttatat tgtttaatag
     4741 cgctgatatt tcatcaatta tgcctgtttt cgtgtttctg gtagttgttc aagtttattg
     4801 ctactatttt tgatggtatg aatgtgctta taatgtatcc cggttaacga aagttttgga
     4861 cttatactct t
//
LOCUS       DAVBBO010000085         4655 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ST1
            SAMEA2066453-rid20184263.denovo.085, whole genome shotgun sequence.
ACCESSION   DAVBBO010000085 DAVBBO010000000
VERSION     DAVBBO010000085.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2066453
            Sequence Read Archive: ERR351777
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 4655)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4655)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980402.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980402.1
            Genome Coverage       :: 176x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:17:33
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,141
            CDSs (total)                      :: 2,104
            Genes (coding)                    :: 1,953
            CDSs (with protein)               :: 1,953
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 16S)
            partial rRNAs                     :: 1 (23S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 151
            CDSs (without protein)            :: 151
            Pseudo Genes (ambiguous residues) :: 0 of 151
            Pseudo Genes (frameshifted)       :: 73 of 151
            Pseudo Genes (incomplete)         :: 76 of 151
            Pseudo Genes (internal stop)      :: 40 of 151
            Pseudo Genes (multiple problems)  :: 32 of 151
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4655
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2066453-rid20184263.denovo.085"
                     /strain="ST1"
                     /db_xref="taxon:1313"
     gene            complement(1..307)
                     /locus_tag="VQU30_002049"
                     /pseudo
     CDS             complement(1..307)
                     /locus_tag="VQU30_002049"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007897432.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(383..817)
                     /locus_tag="VQU30_002050"
     CDS             complement(383..817)
                     /locus_tag="VQU30_002050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000927991.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HET2448089.1"
                     /translation="MLLVLVSLVHSFGSVSIIAHTIHQKFNLKVPNYRQEEDWARMGL
                     PITRKEISNWHIKASQYYLESLYKLLREKLLEQPLLHADETSYRVLESDSHLTYYWTF
                     LSGKAENQAITLYHHDQRRSGLVVQEFLGDYSGYVHCDMLRQ"
     gene            complement(893..1744)
                     /gene="rfbD"
                     /locus_tag="VQU30_002051"
                     /pseudo
     CDS             complement(893..1744)
                     /gene="rfbD"
                     /locus_tag="VQU30_002051"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017647909.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-4-dehydrorhamnose reductase"
     gene            complement(1810..2859)
                     /gene="rfbB"
                     /locus_tag="VQU30_002052"
     CDS             complement(1810..2859)
                     /gene="rfbB"
                     /locus_tag="VQU30_002052"
                     /EC_number="4.2.1.46"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000141505.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-glucose 4,6-dehydratase"
                     /protein_id="HET2448090.1"
                     /translation="MTEYKNIIVTGGAGFIGSNFVHYVYENFPDVHVTVLDKLTYAGN
                     RANIEEILGNRVELVVGDIADAELVDKLVAQADAIVHYAAESHNDNSLNDPSPFIHTN
                     FIGIYTLLEAARKYDIRFHHVSTDEVYGDLPLREDLPGHGEGPGEKFTAETKYNPSSP
                     YSSTKAASDLIVKAWVRSFGVKATISNCSNNYGPYQHIEKFIPRQITNILSGIKPKLY
                     GEGKNVRDWIHTNDHSSGVWTILTKGQIGETYLIGADGEKNNKEVLELILKEMGQATD
                     AYDHVTDRAGHDLRYAIDASKLRDELGWKPEFTNFEAGLKATIKWYTDNQEWWKAEKE
                     AVEANYAKTQEIITV"
     gene            complement(2869..3465)
                     /locus_tag="VQU30_002053"
     CDS             complement(2869..3465)
                     /locus_tag="VQU30_002053"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000131470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-4-dehydrorhamnose 3,5-epimerase family
                     protein"
                     /protein_id="HET2448091.1"
                     /translation="MTDNFFGKTLAARKVEAIPGMLEFDIPVHGDNRGWFKENFQKEK
                     VLPLGFPESFFAEGKLQNNVSFSRKNVLRGLHAEPWDKYISVADGGKVLGSWVDLREG
                     ETFGNTYQTVIDASKGIFVPRGVANGFQVLSDTVSYSYLVNDYWALELKPKYAFVNYA
                     DPSLGIEWENLEEADVSEADKHHPLLKDVKPLKKEDLE"
     gene            complement(3466..4323)
                     /gene="rfbA"
                     /locus_tag="VQU30_002054"
     CDS             complement(3466..4323)
                     /gene="rfbA"
                     /locus_tag="VQU30_002054"
                     /EC_number="2.7.7.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000676139.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-1-phosphate thymidylyltransferase RfbA"
                     /protein_id="HET2448092.1"
                     /translation="MKGIILAGGSGTRLYPLTRAASKQLMPVYDKPMIYYPLSTLMLA
                     GIRDILIISTPQDLHRFQELLQDGSEFGIKLSYAEQPSTDGLAIGEEFISDDSVALIL
                     GDNIYHGPGLSTMLQKAAKKEKGATVFGYQVKDPERFGVVEFDTDMNAISIEEKPEYP
                     RSNYAVTGLYFYDNDVVEIAKSIKPSPRGELEITDVNKAYLDRGDLSVELMGRGFAWL
                     NTGTHESLLEASQYIETVQRMQNVQVANLEEIAYRMGYISREDVLALAQPLKKNEYGQ
                     YLLRLIGEA"
BASE COUNT         1325 a         1075 c          842 g         1413 t
ORIGIN      
        1 attcaattgc ccttcctagt tttgaacctg ctaaaactga ctgacgccgg caccaagcaa
       61 agaagtcttc cattaggggc tggagatgtt cttgacgttt ctgtagtcgt tcatcagctg
      121 gcaaagcctc ccagtctctt tccagggaaa ataactgatc acaataagct aaacctttag
      181 ctcctaagga tgatttatcc gtttgcttgg ggggcgcttc aaaaaacttc cttctcacat
      241 gtgcccaaca tccaacaagt tcagcttctt ccagttgacg ataagcttct agcggttcgc
      301 agtttaccaa gcttagcgtc gccttgctcc taaaccttgg actgctatcg cataggcaga
      361 actagaggac taaagtccta agttactgcc gcaacatatc acaatgcaca tagccagaat
      421 aatctcctag gaattcttgt actactaaac cactccgacg ctgatcatgg tggtacagcg
      481 tgattgcttg attctcagct ttcccagaca aaaaagtcca atagtaggtc agatggctat
      541 cactctctag aacccgataa gaggtttcat ccgcatgaag aagaggttgt tctaacaact
      601 tttctcgtaa aagcttataa agggactcta aatagtattg acttgccttg atatgccaat
      661 tagagatttc cttacgtgtg attggtaaac ccatcctagc ccaatcttct tcttggcgat
      721 aattgggtac cttcagatta aacttctgat ggatggtgtg agcgataata gaaactgagc
      781 caaagctatg caccaaagag accagcacca acaacaagat aattgtacat cttaagctcc
      841 tttggagttc attatctgcc tcttttatta gactagaaaa tcattctact acttatctca
      901 cttcttgttt gtaaaattct tgcaatgcat cttgccaagt tggaataaca aatccagtag
      961 ctttggcttt ggccaggctc atcgttgagt ttagcggacg ttgagctttg gctggaaatt
     1021 gactggaatc tactggcttg acttcgacat ctgtatcttt caaaatttca actgcaaaat
     1081 cataccatgt tgtgtcttct gtcgcatcat ttgacaaatg ataataacca aattccttac
     1141 gattttcagc taggtagatc atgaattcag ccaaggtacg agtccaagtc ggacgaccgt
     1201 actggtcatt tacaactgtt aaagtcttat gagttttcgc aagattttgc atggtaaaaa
     1261 cgaagttttt gccataattt ccaaataccc aggcagtacg gataatatag aaattagaca
     1321 catgcttctc aactaactct tcccccatac gcttagtgcg tccatattct gtctgtggat
     1381 ctggtcggtc atcaacttcc cactcttgtc caactggttt cttaccgtca aagacctagt
     1441 ccgtagaaat ataaactaga gttgcaccat gcttttcaga tgcttttgcg acattttttg
     1501 tccccatcac attgatggcg aagtccaact cttttccttc atcctctgct gcatcaacag
     1561 cggtgtaggc tgcacaatgg tagactaaag tcggtttcac ctcttcaaaa actttctcaa
     1621 ccatttcttc attggtaatg tccatctcag ccacatctac tgccacgtat tcttcattac
     1681 gttcatccaa taaatagcga agttccgttc ctaattggcc atttgcccct gtaattaaaa
     1741 tcatctctag acctttctaa tatgtaactc ttcccaatat agcaataaaa agcagcgatt
     1801 tcctgctttt tatactgtaa taatctcctg agtcttagca taattggctt caacagcttc
     1861 tttttctgct ttccaccatt cttggttatc tgtataccac ttgattgttg ccttgagccc
     1921 agcttcaaag ttggtaaatt caggtttcca ccccaactca tcacggagct tgctggcatc
     1981 aatcgcatag cgaaggtcat gtcctgcacg gtcagtcaca tgatcatagg catccgtagc
     2041 ttgtcccatt tccttaagga taagttccaa aacttcctta ttgttcttct caccatcagc
     2101 cccaatcaag taggtttcac cgatttgccc ttttgtcaag attgtccaaa ctcctgaaga
     2161 atggtcattg gtatgaatcc agtcacgaac gttcttacct tcaccgtaaa gttttggctt
     2221 aattccactt aggatgttag taatctgacg tgggatgaat ttttcgatat gttgataagg
     2281 accgtagtta tttgaacagt tggaaatcgt tgccttgact ccaaaagaac gcacccaggc
     2341 tttgacaatc aagtctgatg cggccttggt tgatgagtac ggagagcttg ggttgtattt
     2401 tgtttcagca gtaaatttct cacctggtcc ttcaccatga cctggcaaat cttctcgtaa
     2461 agggagatcc ccataaactt catctgtcga tacatggtgg aagcgaatat catacttacg
     2521 agcagcttct aaaagagtat agattccaat gaagttagta tgaataaatg gcgatggatc
     2581 attgagcgaa ttatcattgt ggctttccgc tgcataatga acgatagcat ctgcttgagc
     2641 aaccaacttg tctaccaact ccgcatcagc aatgtcacca acaactaact caacacgatt
     2701 gcctaaaatt tcctcaatat tcgcgcggtt tccagcataa gtcaacttat ctaggactgt
     2761 cacgtgaaca tctggaaagt tctcgtaaac ataatggaca aagttagaac cgataaagcc
     2821 agctccacct gtcacgataa tatttttgta ttcagtcata ttctttcctt attccaaatc
     2881 ttcttttttc aaaggcttca cgtccttaag taggggatga tgtttgtctg cttcagatac
     2941 gtctgcttct tccagatttt cccattcaat accaaggctt ggatcagcgt agttcacaaa
     3001 ggcatacttg ggtttgagtt caagagccca gtaatcattg accagatagc tatatgacac
     3061 tgtatctgat aaaacttgga agccattagc tacgcctcga ggaacaaaga ttcccttgct
     3121 tgcatcaatt actgtctgat aggtattccc aaaggtttca ccctcgcgta gatcaaccca
     3181 agaacccaga actttccctc catctgctac agagatgtac ttatcccaag gctctgcgtg
     3241 gaggcctcga aggacatttt tacgtgagaa ggatacattg ttttgcaatt ttccttctgc
     3301 aaagaaagac tctggaaatc caagtggaag cactttttcc ttttggaaat tttctttaaa
     3361 ccagccacga ttatctccat gaacggggat atcaaactcc aacatgcctg gaatagcttc
     3421 aaccttgcgt gccgcaagcg tcttaccgaa aaaattatct gtcatctatg cttctccaat
     3481 caaacggagc agatactgtc cgtattcatt tttcttaagt ggttgggcta aggccaatac
     3541 atcttctcga ctgatatagc ccatacggta agcaatttct tctaagtttg ctacctgaac
     3601 attttgcatc cgttgcactg tttcgatgta ctgtgaagcc tctagtaaac tttcatgagt
     3661 tccagtattc agccaagcaa agccacgtcc cataagctca acagacaaat caccacgatc
     3721 taggtaagcc ttgtttacat ctgtaatttc cagttcacca cgagggcttg gtttaatact
     3781 cttggcaatt tcgacaacat cgttatcata gaaatacagt cctgtcactg catagttgga
     3841 gcgaggatac tccggttttt cttctatgga aatagcattc atgtctgtat caaactcaac
     3901 cacaccaaaa cgctctggat ccttcacttg gtagccaaaa acagtcgcac ctttctcttt
     3961 cttggctgct ttttgaagca ttgtgctcag accaggacca tggtagatat tgtcgcctaa
     4021 aatcaaggca acgctatcgt cagaaataaa ctcttcccca attgccaaac catctgtact
     4081 tggttgctct gcataagaaa gtttgatccc aaactcagat ccgtcttgaa gaagctcttg
     4141 aaatcgatgt aaatcctgtg gagtggaaat aatcaaaata tccctaatcc cagccaacat
     4201 caatgttgaa agtgggtagt aaatcatcgg tttatcataa accggcataa gttgttttga
     4261 cgcagcgcga gtcaaaggat ataaacgtgt ccccgaacca cctgctagaa taataccttt
     4321 catagtaggg tacctttctt tgttatttta gagtcaatta ctattaattg tgtactgctc
     4381 taaaaagaaa acaatcatcc catgttttat atggctctat aatatttgta gtgggtaaat
     4441 ccactataga tattatggag cctattttat tgtagaaaaa aagtcccata agatctataa
     4501 tgaaaagcga ccaaacaact cattagaaag attcatatgg gacaattaca ttttatcaca
     4561 aaactactcg atatcaaaga cccaaacatc aagattctag atatcatcaa tatggatacc
     4621 cacaaagaaa ttatcgctaa gctggattat gaggc
//
LOCUS       DAVBBO010000086         4574 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ST1
            SAMEA2066453-rid20184263.denovo.086, whole genome shotgun sequence.
ACCESSION   DAVBBO010000086 DAVBBO010000000
VERSION     DAVBBO010000086.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2066453
            Sequence Read Archive: ERR351777
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 4574)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4574)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980402.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980402.1
            Genome Coverage       :: 176x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:17:33
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,141
            CDSs (total)                      :: 2,104
            Genes (coding)                    :: 1,953
            CDSs (with protein)               :: 1,953
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 16S)
            partial rRNAs                     :: 1 (23S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 151
            CDSs (without protein)            :: 151
            Pseudo Genes (ambiguous residues) :: 0 of 151
            Pseudo Genes (frameshifted)       :: 73 of 151
            Pseudo Genes (incomplete)         :: 76 of 151
            Pseudo Genes (internal stop)      :: 40 of 151
            Pseudo Genes (multiple problems)  :: 32 of 151
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4574
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2066453-rid20184263.denovo.086"
                     /strain="ST1"
                     /db_xref="taxon:1313"
     gene            51..1596
                     /locus_tag="VQU30_002055"
     rRNA            51..1596
                     /locus_tag="VQU30_002055"
                     /product="16S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00177"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00177"
     gene            1648..1720
                     /locus_tag="VQU30_002056"
     tRNA            1648..1720
                     /locus_tag="VQU30_002056"
                     /product="tRNA-Ala"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1681..1683,aa:Ala,seq:tgc)
     gene            1845..>4574
                     /locus_tag="VQU30_002057"
     rRNA            1845..>4574
                     /locus_tag="VQU30_002057"
                     /product="23S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF02541"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF02541"
BASE COUNT         1257 a          946 c         1366 g         1005 t
ORIGIN      
        1 gaaaaaaaca ataaatctgt cagtgacaga aatgagtgag aactcaaact tttaatgaga
       61 gtttgatcct ggctcaggac gaacgctggc ggcgtgccta atacatgcaa gtagaacgct
      121 gaaggaggag cttgcttctc tggatgagtt gcgaacgggt gagtaacgcg taggtaacct
      181 gcctggtagc gggggataac tattggaaac gatagctaat accgcataag agtagatgtt
      241 gcatgacatt tgcttaaaag gtgcacttgc atcactacca gatggacctg cgttgtatta
      301 gctagttggt gggataacgg ctcaccaagg cgacgataca tagccgacct gagagggtga
      361 tcggccacac tgggactgag acacggccca gactcctacg ggaggcagca gtagggaatc
      421 ttcggcaatg gacggaagtc tgaccgagca acgccgcgtg agtgaagaag gttttcggat
      481 cgtaaagctc tgttgtaaga gaagaacgag tgtgagagtg gaaagttcac actgtgacgg
      541 tatcttacca gaaagggacg gctaactacg tgccagcagc cgcggtaata cgtaggtccc
      601 gagcgttgtc cggatttatt gggcgtaaag cgagcgcagg cggttagata agtctgaagt
      661 taaaggctgt ggcttaacca tagtaggctt tggaaactgt ttaacttgag tgcaagaggg
      721 gagagtggaa ttccatgtgt agcggtgaaa tgcgtagata tatggaggaa caccggtggc
      781 gaaagcggct ctctggcttg taactgacgc tgaggctcga aagcgtgggg agcaaacagg
      841 attagatacc ctggtagtcc acgctgtaaa cgatgagtgc taggtgttag accctttccg
      901 gggtttagtg ccgtagctaa cgcattaagc actccgcctg gggagtacga ccgcaaggtt
      961 gaaactcaaa ggaattgacg ggggcccgca caagcggtgg agcatgtggt ttaattcgaa
     1021 gcaacgcgaa gaaccttacc aggtcttgac atccctctga ccgctctaga gatagagttt
     1081 tccttcggga cagaggtgac aggtggtgca tggttgtcgt cagctcgtgt cgtgagatgt
     1141 tgggttaagt cccgcaacga gcgcaacccc tattgttagt tgccatcatt tagttgggca
     1201 ctctagcgag actgccggta ataaaccgga ggaaggtggg gatgacgtca aatcatcatg
     1261 ccccttatga cctgggctac acacgtgcta caatggctgg tacaacgagt cgcaagccgg
     1321 tgacggcaag ctaatctctt aaagccagtc tcagttcgga ttgtaggctg caactcgcct
     1381 acatgaagtc ggaatcgcta gtaatcgcgg atcagcacgc cgcggtgaat acgttcccgg
     1441 gccttgtaca caccgcccgt cacaccacga gagtttgtaa cacccgaagt cggtgaggta
     1501 accgtaagga gccagccgcc taaggtggga tagatgattg gggtgaagtc gtaacaaggt
     1561 agccgtatcg gaaggtgcgg ctggatcacc tcctttctaa ggataaggaa ctgcgcattg
     1621 gtcttgttta gtcttgagag gtcttgtggg gccttagctc agctgggaga gcgcctgctt
     1681 tgcacgcagg aggtcagcgg ttcgatcccg ctaggctcca ttggtgagag atcaccaagt
     1741 aatgcacatt gaaaattgaa tatctatatc aaatagtaac aagaaaataa accgaaaacg
     1801 ctgtagtatt aataagagtt tatgactgaa aggtcagaaa ataaggttaa gttaataagg
     1861 gcgcacggtg gatgccttgg cactaggagc cgacgaagga cgtgacaaac gacgatatgc
     1921 cttgggtagc tgtaagtaag cgatgatcca gggatttccg aatgggggaa cccaacaggt
     1981 agtacctgtt acccacatct gttaaggatg tgaggaggaa gacgcagtga actgaaacat
     2041 ctaagtagct gcaggaagag aaagcaaaag cgattgcctt agtagcggcg agcgaaacgg
     2101 caggagggca aaccgaagag tttactcttc ggggttgtag gactgcaatg tggactcaaa
     2161 gattatagaa gaatgatttg ggaagatcag ccaaagagag taatagcctc gtatttaaaa
     2221 tagtctttgt acctagcagt atcctgagta cggcgggaca cgtgaaatcc cgtcggaatc
     2281 tgggaggacc atctcccaac cctaaatact ccctagtgac cgatagtgaa ccagtaccgt
     2341 gagggaaagg tgaaaagcac cccgggaggg gagtgaaata gaacctgaaa ccgtgtgcct
     2401 acaacaagtt cgagcccgtt aatgggtgag agcgtgcctt ttgtagaatg aaccggcgag
     2461 ttacgttatg atgcgaggtt aagttgaaga gacggagccg tagggaaacc gagtctgaat
     2521 agggcgcctt agtatcatga cgtagacccg aaaccatgtg acctacccat gagcaggttg
     2581 aaggtgcggt aagacgcact ggaggaccga accagggcac gttgaaaagt gcttggatga
     2641 cttgtgggta gcggagaaat tccaaacgaa cttggagata gctggttctc tccgaaatag
     2701 ctttagggct agcgtcgaca ttagagattc ttggaggtag agcactgttt gggtgagggg
     2761 tccatcccgg attaccaatc tcagataaac tccgaatgcc aatgaattat ggtcggcagt
     2821 cagactgcga gtgctaagat ccgtagtcga aagggaaaca gcccagacca ccagctaagg
     2881 tcccaaaata attgttaagt ggaaaaggat gtggggttgc acagacaact aggatgttag
     2941 cttagaagca gctattcatt caaagagtgc gtaatagctc actagtcgag tgaccctgcg
     3001 ccgaaaatgt accggggcta aaacaattta ccgaagctgt ggataccttt ataggtatgg
     3061 taggagagcg ttctatgtgt gatgaaggta taccgtgagg agtgctggaa cgcatagaag
     3121 tgagaatgcc ggtatgagta gcgaaagaca ggtgagaatc ctgtccaccg taagactaag
     3181 gtttccaggg gaaggctcgt ccgccctggg ttagtcggga cctaaggaga gaccgaaagg
     3241 tgtatccgat ggacaacagg ttgatattcc tgtactagag tatgtagtga tggagggacg
     3301 cagtaggcta actaaagcag acgattggaa gagtctgtct aagcagtgag gtgtgatatg
     3361 agtcaaatgc ttatatctgt aacattgagc tgtgatgggg agcgaagttt agtagcgaag
     3421 ttagtgacgt cacactgcca agaaaagctt ctagcgttta aacatactct acccgtaccg
     3481 caaaccgaca caggtagtcg aggcgagtag cctcaggtga gcgagagaac tctcgttaag
     3541 gaactcggca aaatgacccc gtaacttcgg gagaaggggt gctgacttta agtcagccgc
     3601 agtgaatagg cccaagcaac tgtttatcaa aaacacagct ctctgctaaa tcgtaagatg
     3661 atgtataggg ggtgacgcct gcccggtgct ggaaggttaa gaggagtgct tagcgtaagc
     3721 gaaggtatga attgaagccc cagtaaacgg cggccgtaac tataacggtc ctaaggtagc
     3781 gaaattcctt gtcgggtaag ttccgacccg cacgaaaggc gtaatgattt gggcactgtc
     3841 tcaacgagag actcggtgaa attttagtac ctgtgaagat gcaggttacc cgcgacagga
     3901 cggaaagacc ccatggagct ttactgcagt ttgatattga gtgtctgtac cacatgtaca
     3961 ggataggtag gagtctaaga gatcgggacg ccagtttcga aggagacgct gttgggatac
     4021 tacccttgtg ttatggccac tctaacccag ataggtgatc cctatcggag acagtgtctg
     4081 acgggcagtt tgactggggc ggtcgcctcc taaaaggtaa cggaggcgcc caaaggttcc
     4141 ctcagaatgg ttggaaatca ttcgcagagt gtaaaggtat aagggagctt gactgcgaga
     4201 gctacaactc gagcagggac gaaagtcggg cttagtgatc cggtggttcc gtatggaagg
     4261 gccatcgctc aacggataaa agctaccctg gggataacag gcttatctcc cccaagagtt
     4321 cacatcgacg gggaggtttg gcacctcgat gtcggctcgt cgcatcctgg ggctgtagtc
     4381 ggtcccaagg gttgggctgt tcgcccatta aagcggcacg cgagctgggt tcagaacgtc
     4441 gtgagacagt tcggtcccta tccgtcgcgg gcgtaggaaa tttgagagga tctgctccta
     4501 gtacgagagg accagagtgg acttaccgct ggtgtaccag ttgtcttgcc aaaggcatcg
     4561 ctgggtagct atgt
//
LOCUS       DAVBBO010000087         4552 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ST1
            SAMEA2066453-rid20184263.denovo.087, whole genome shotgun sequence.
ACCESSION   DAVBBO010000087 DAVBBO010000000
VERSION     DAVBBO010000087.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2066453
            Sequence Read Archive: ERR351777
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 4552)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4552)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980402.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980402.1
            Genome Coverage       :: 176x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:17:33
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,141
            CDSs (total)                      :: 2,104
            Genes (coding)                    :: 1,953
            CDSs (with protein)               :: 1,953
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 16S)
            partial rRNAs                     :: 1 (23S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 151
            CDSs (without protein)            :: 151
            Pseudo Genes (ambiguous residues) :: 0 of 151
            Pseudo Genes (frameshifted)       :: 73 of 151
            Pseudo Genes (incomplete)         :: 76 of 151
            Pseudo Genes (internal stop)      :: 40 of 151
            Pseudo Genes (multiple problems)  :: 32 of 151
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4552
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2066453-rid20184263.denovo.087"
                     /strain="ST1"
                     /db_xref="taxon:1313"
     gene            complement(112..549)
                     /locus_tag="VQU30_002058"
     CDS             complement(112..549)
                     /locus_tag="VQU30_002058"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269962.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CoA-binding protein"
                     /protein_id="HET2448093.1"
                     /translation="MSQEFINPSDGVIRQYLATSKTLAVVGLSDREETTSNRVTKEMQ
                     ARGYKIIPVNPKAAGGEILGEKAYASLAEIPFPVDIVNVYRRSEFLPDVARDFLKADA
                     KIFWAQLGLESLEAKEILRDGGCDDIVMNRCIKREHTRLIEEA"
     gene            complement(634..3267)
                     /gene="polA"
                     /locus_tag="VQU30_002059"
     CDS             complement(634..3267)
                     /gene="polA"
                     /locus_tag="VQU30_002059"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014932012.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase I"
                     /protein_id="HET2448094.1"
                     /translation="MDKKKLLLIDGSSVAFRAFFALYQQLDRFKNAAGLHTNAIYGFQ
                     LMLSHLLERVEPSHILVAFDAGKTTFRTEMYADYKGGRAKTPDEFREQFPFIRELLDH
                     MGIRHYELAQYEADDIIGTLDKLAEQDGFDITIVSGDKDLIQLTDEHTVVEISKKGVA
                     EFEAFTPDYLMEEMGLTPAQFIDLKALMGDKSDNIPGVTKVGEKTGIKLLLEHGSLEG
                     IYENIDGMKTSKMKENLINDKEQAFLSKTLATIDTKAPIAIGLEDLVYSGPDVENLGK
                     FYDEMGFKQLKQALNVSSADVAEGLDFTIVDQISQDMLSEESIFHFELFGENYHTDNL
                     VGFAWSCGDKLYATDKLELLQDPIFKDFLEKTSLRVYDFKKVKVLLQRFGVDLQAPAF
                     DIRLAKYLLSTVEDNEIATIASLYGQTYLVDDETFYGKGVKKAIPEREKFLEHLACKL
                     AVLVETEPILLEKLSENGQLELLYDMEQPLAFVLAKMEIAGIVVKKETLLEMQAENEL
                     VIEKLTQEIYELAGEEFNVNSPKQLGVLLFEKLGLPLEYTKKTKTGYSTAVDVLERLA
                     PIAPIVKKILDYRQIAKIQSTYVIGLQDWILADGKIHTRYMQDLTQTGRLSSVDPNLQ
                     NIPARLEQGRLIRKAFVPEWEDSVLLSSDYSQIELRVLAHISKDEHLIKAFQEGADIH
                     TSTAMRVFGIERPDNVTANDRRNAKAVNFGVVYGISDFGLSNNLGISRKEAKAYIDTY
                     FERFPGIKNYMDEVVREARDKGYVETLFKRRRELPDINSRNFNIRGFAERTAINSPIQ
                     GSAADILKIAMIQLDKALVAGGYQTKMLLQVHDEIVLEVPKSELVEMKKLVKQTMEEA
                     IQLSVPLIADENEGATWYEAK"
     gene            3520..3873
                     /locus_tag="VQU30_002060"
     CDS             3520..3873
                     /locus_tag="VQU30_002060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001811778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PD-(D/E)XK nuclease family transposase"
                     /protein_id="HET2448095.1"
                     /translation="MILRHLGISPTNDLVAKKIFSNPEITCQFIRDMLDLPAKNVTIL
                     EGSNIHVLPSMPYSAQDFYTSIDVLAELDNGTQVIIEIQVHHQNFFINHLWAYLCSQV
                     NQNLEKIRQREGDTH"
     gene            4088..4204
                     /locus_tag="VQU30_002061"
     CDS             4088..4204
                     /locus_tag="VQU30_002061"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000233180.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="damage-inducible protein CinA"
                     /protein_id="HET2448096.1"
                     /translation="MVGVFRQQALYPATATSHYPSKSTAGLQELVRGGQENV"
     gene            4197..4430
                     /locus_tag="VQU30_002062"
     CDS             4197..4430
                     /locus_tag="VQU30_002062"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2448097.1"
                     /translation="MFSQLHMREEQVLLAQDYALETARAEGLEQGLERGKVEGRAERK
                     LFAFLDIVRQGLLTSEVASQQLGMSVSEFEALL"
BASE COUNT         1385 a         1096 c          837 g         1234 t
ORIGIN      
        1 gtatctacaa cctcaaaaca gtgttttgag cagcccgcga ctagtttcct agtttgctct
       61 ttgattttca ttgagtataa cacaaaaggt agcccatcag ctaccttttt cttatgcttc
      121 ctcaatcaag cgagtatgtt ctctcttgat acagcgattc atcacgatat catcacatcc
      181 accatcacgc aaaatctctt tcgcttctaa actttcaagt cctagctgtg cccaaaaaat
      241 cttggcatca gctttgagaa aatcacgcgc cacatcgggc agaaattcac tgcgacgata
      301 aacattgaca atatctacag gaaaaggaat ttcagcgagg ctagcataag ccttttcacc
      361 caagatttcg ccacctgccg ccttgggatt gactgggatg attttatagc cccgagcctg
      421 catttccttt gtcactcgat tgctggttgt ttcttcacgg tcagacaaac ccaccacagc
      481 aagggtttta ctcgttgcga gatactgacg aatcacgcca tcacttggat tgataaattc
      541 ttgactcata gaaaacctcc tttttcatca gtatagcaca ttttgaaaag gtttgcagaa
      601 ttctactaca aaaaaggagg actagccccc tttttattta gcctcgtacc aggttgcccc
      661 ttcattctca tctgcgataa gaggaacact gagttgaatg gcttcttcca tggtttgttt
      721 caccaatttt ttcatctcta ccaattcaga tttaggcact tcaaggacga tttcatcgtg
      781 cacttgtaac agcatcttag tctgataacc acctgcaacc aaggctttat ccagctgaat
      841 catggcaatc ttgagaatat ctgctgccga accctggata ggtgagttga tagcagttcg
      901 ctccgcaaaa ccacgaatat tgaagttgcg cgaattgata tctggcaact cacggcgacg
      961 cttaaagagg gtctctacat agcccttatc acgcgcctcc cgcaccactt catccatgta
     1021 gtttttaata cctggaaaac gttcaaagta ggtatcaatg taggctttgg cttccttacg
     1081 actaattccc aaattattag acaagccaaa gtctgaaatc ccataaacca ctccaaagtt
     1141 aactgccttg gcattgcgac gatcatttgc agtcacatta tcaggacgct caatgccaaa
     1201 gacccgcatg gctgtcgaag tatggatatc tgccccctct tggaaggcct taatcaagtg
     1261 ctcatcctta gaaatatgcg ccaaaacgcg caattcaatc tgtgaatagt cagagctgag
     1321 tagcacacta tcctcccact ctggcacaaa agccttccga atcaagcgcc cttgttccaa
     1381 tcgggcagga atattttgca agtttggatc cacactagac aaacgcccgg tctgggtcaa
     1441 atcctgcata tagcgagtat gaatctttcc atcagccaaa atccagtcct gcaagccaat
     1501 tacataagta gattgaatct tagcaatttg acggtaatcc aggattttct taacaatcgg
     1561 agcaatagga gcgagacgct ccaacacatc cactgctgtc gaataacctg tcttggtttt
     1621 cttagtgtat tctagaggaa gtcccaattt ctcaaagaga agcacgccca actgcttagg
     1681 cgagttgaca ttaaactcct caccagccag ctcgtaaatc tcttgagtca gtttttcaat
     1741 gacaagctca ttttcagcct gcatctcaag caaggtctct ttcttgacca caatcccagc
     1801 aatttccatc ttggcaagaa caaaagccag aggttgctcc atatcataaa gaagctctaa
     1861 ttgcccattt tcgctgagtt tttcaagtaa aataggctct gtttctacca aaacagcaag
     1921 tttacaagct aagtgttcca agaatttctc acgttcagga atggcctttt taacaccctt
     1981 accgtagaaa gtttcatcat caaccaagta agtctgacca taaagactag cgatggtcgc
     2041 aatttcattg tcctccacag tcgaaaggag gtatttagcc aaacggatgt caaaagcagg
     2101 cgcctgcaaa tccacaccaa aacgttgcaa aagaacttta accttcttaa agtcataaac
     2161 tctcagagat gttttttcta agaaatcctt gaaaatcggg tcttgcaaca gctcaagctt
     2221 gtctgtggca tagagcttat ccccacaaga ccaggcaaat ccaaccaaat tatccgtatg
     2281 ataattctca ccaaaaagct caaagtggaa gatagactct tcactcagca tatcttgact
     2341 gatttggtca acaatagtaa aatccaaacc ctcagccaca tcagctgacg acacatttaa
     2401 agcctgcttg agctgtttga atcccatctc atcgtaaaat ttcccaagat tttcaacatc
     2461 tggaccacta tagaccaagt cctctaaacc aatcgcaatc ggtgccttgg tatcaatggt
     2521 cgctagtgtt ttagacaaaa aggcctgttc cttgtcattg atgagatttt ccttcatctt
     2581 agaagtcttc attccatcaa tattttcata aatcccctca agcgaaccat gctccagcaa
     2641 gagcttaata cccgtctttt caccgacttt ggtcacccca gggatattat ccgacttatc
     2701 acccatgagc gccttgagat cgataaactg agctggtgtg aggcccattt cttccatgag
     2761 gtaatctggc gtaaaggcct caaactcagc cacacctttc ttggaaattt caaccaccgt
     2821 atgctcatcc gtcagctgaa tcaaatcctt gtccccactg acaatggtaa tatcaaaacc
     2881 atcctgctct gctagcttat ccaacgtccc aatgatgtca tccgcctcat actgagccag
     2941 ctcatagtga cgaatcccca tatgatccag caactcacga atgaaaggaa attgctcacg
     3001 aaactcatca ggagtcttgg cccgaccacc cttatagtcc gcatacatct ctgtccggaa
     3061 ggtcgtcttt cccgcatcaa aagccaccaa aatatgactc ggctcaaccc gctccaacaa
     3121 atgactcaac atcaactgaa aaccataaat cgcattggta tgcaaaccag ccgcattctt
     3181 aaaacggtcc aactgctgat acagcgcaaa aaacgcccga aaagctacag aagacccatc
     3241 aatcaataat aattttttct tatccataca cccattataa aggaaagaat caaaaaatac
     3301 cattgggaag agctagagca agtatttttc aaactttttc cgaataaata gatagagcca
     3361 gagaatttag taaacctaga tttaaaaatg tgctataata tagtatattg aatctataat
     3421 agtacacctt gactgctaaa atatttctat aaattaattt gactttcctg atagagttgt
     3481 tcacatctta tttcaattca ctatagaagg aggaaaagga tgattctcag acatctggga
     3541 attagcccga ccaatgactt ggttgctaag aaaattttca gcaacccaga aatcacttgt
     3601 caatttatcc gcgatatgct ggacttgcca gccaaaaatg tgactatttt ggagggaagt
     3661 aacattcatg tcttgccttc catgccctac tcagcgcagg atttttatac cagtatagac
     3721 gtcttggcgg agttggataa cggtactcaa gtaattattg agattcaagt ccatcatcag
     3781 aattttttca tcaatcactt gtgggcttac ctgtgcagtc aggttaatca aaatcttgaa
     3841 aaaattcgtc agcgagaagg tgatactcac tagatctaca aacacatcgc tcctgtttac
     3901 gtcattgcta tcgtggatag taattatttc tcagatgacc tggcttttca tagctttagt
     3961 atgcgcgaag acacaacagg tgaggtattg gcgattacca acaatggaca ggaaaaccat
     4021 ctggttaaga tggcattctt ggaattaaaa aatacagaga aaccagcaaa gacaaggttc
     4081 gcaagccatg gttggagttt ttcggcaaca agccctttac ccagcaaccg caacgagcca
     4141 ttacccaagc aaatcaactg ctggactaca agagctggtc cgaggaggac aggaaaatgt
     4201 ttagtcaact acatatgcga gaagaacaag tcttgttagc acaggactat gccttggaaa
     4261 ctgctagggc tgaaggcctt gaacaaggac tagagcgtgg gaaagttgaa ggaagggcag
     4321 aaaggaaact ttttgccttc ctagacatag tacgccaagg tcttctgact tctgaggttg
     4381 ccagccagca attaggtatg tcagtatctg aatttgaggc actgttgtaa aatggctcca
     4441 taatatccat agtgggtaaa tcccctatgg atattatgga gcctattttt gtgtagaaaa
     4501 aaagtcccat atgacctata atgaaaagcg acaaaacaac tcattaaaaa ga
//
LOCUS       DAVBBO010000088         4546 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ST1
            SAMEA2066453-rid20184263.denovo.088, whole genome shotgun sequence.
ACCESSION   DAVBBO010000088 DAVBBO010000000
VERSION     DAVBBO010000088.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2066453
            Sequence Read Archive: ERR351777
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 4546)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4546)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980402.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980402.1
            Genome Coverage       :: 176x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:17:33
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,141
            CDSs (total)                      :: 2,104
            Genes (coding)                    :: 1,953
            CDSs (with protein)               :: 1,953
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 16S)
            partial rRNAs                     :: 1 (23S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 151
            CDSs (without protein)            :: 151
            Pseudo Genes (ambiguous residues) :: 0 of 151
            Pseudo Genes (frameshifted)       :: 73 of 151
            Pseudo Genes (incomplete)         :: 76 of 151
            Pseudo Genes (internal stop)      :: 40 of 151
            Pseudo Genes (multiple problems)  :: 32 of 151
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4546
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2066453-rid20184263.denovo.088"
                     /strain="ST1"
                     /db_xref="taxon:1313"
     gene            <1..141
                     /locus_tag="VQU30_002063"
     CDS             <1..141
                     /locus_tag="VQU30_002063"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HET2448098.1"
                     /translation="LLPLPPYSPEYNPIEKTWAHIKKHLKKVLPSCNTFYEALLSCSC
                     FN"
     gene            complement(134..307)
                     /locus_tag="VQU30_002064"
     CDS             complement(134..307)
                     /locus_tag="VQU30_002064"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001022221.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S-ribosylhomocysteinase"
                     /protein_id="HET2448099.1"
                     /translation="MNIKKRVLSAGLTFASVLLLAACGQSGSDTKTYSSTFSGNPTTF
                     NYLLDYYTDNIVN"
     gene            complement(465..2072)
                     /locus_tag="VQU30_002065"
     CDS             complement(465..2072)
                     /locus_tag="VQU30_002065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-glucosidase"
                     /protein_id="HET2448100.1"
                     /translation="MQEKWWHNAVVYQVYPKSFMDSNGDGIGDLPGITSKLDYLAKLG
                     ITAIWLSPVYDSPMDDNGYDIADYQAIAAIFGTMEDMDQLIAEAKKRDIRIIMDLVVN
                     HTSDEHAWFVEACENPNSPERDYYIWRDEPNDLDSIFSGSAWEYDEKSGQYYLHFFSK
                     KQPDLNWENEKLRQKIYEMMNFWIDKGIGGFRMDVIDMIGKIPDEKVVNNGPMLHPYL
                     KEMNQATFGDKDLLTVGETWGATPEIAKLYSDPKGQELSMVFQFEHIGLQYQEGQPKW
                     HYQKELNIAKLKEIFNKWQTELGVEDGWNSLFWNNHDLPRIVSIWGNDQEYREKSAKA
                     FAILLHLMRGTPYIYQGEEIGMTNYPFETLDQVEDIESLNYAREALEKGVPIEEIMDS
                     IRVIGRDNARTPMQWDESKNAGFSTGQPWLAVNPNYEMINVQEALANPDSIFYTYQKL
                     VQIRKENSWLVRADFELLDTADKVFAYIRKDGDRRFLVVANLSNEEQDLTVEGKVKSV
                     LIENTLAQEVFEKQILVPWDAFCVELL"
     gene            2225..3709
                     /locus_tag="VQU30_002066"
     CDS             2225..3709
                     /locus_tag="VQU30_002066"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008535024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1846 domain-containing protein"
                     /protein_id="HET2448101.1"
                     /translation="MKKQAFSSEQYLNLQRDHILERINQFDGKLYLEFGGKMLEDFHA
                     ARVLPGYEPDNKIKLLQELKEQVEVVIAINASNIEHSKARGDLGISYDQEVLRLIDKF
                     NELGIFVGSVVITQYAGQPAADAFLNQLEKNGIDSYLHYPIKGYPTDMDHIISPEGMG
                     KNDYIKTSRNLIVVTAPGPGSGKLATCMSNMYHDQINGIKSGYAKFETFPVWNLPLHH
                     PVNLAYEAATADLDDVNMIDPFHLQTYGETTVNYNRDIEIFPVLKRMLERILGKSPYA
                     SPTDMGVNMVGFAITDDEAAVEASKQEIIRRYYQTVLDFKAEKVGEAAVKKIELLMND
                     LGISPADRKVAVVARQKAEETGGPALALELPNGDIVTGKNSELFGPTAAALINAIKKS
                     ADIAKEVKLIEPEVVKPIQGLKIDHLGSRNPRLHSNEILIALAITATENPDAARAMEE
                     LGNLKGSEAHSTIILTDEDKNVLRKLGINVTFDPYYQYDRLYRK"
     gene            3804..4286
                     /locus_tag="VQU30_002067"
     CDS             3804..4286
                     /locus_tag="VQU30_002067"
                     /EC_number="4.4.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002893508.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S-ribosylhomocysteine lyase"
                     /protein_id="HET2448102.1"
                     /translation="MSKEVIVESFELDHTIVKAPYVRLIGEETGPKGDIISNYDIRLV
                     QPNEDSIPTAGLHTIEHLLAKLIRTRIDGMIDCSPFGCRTGFHMIMWGRHTSAKIAAV
                     IKDSLKEIAETTTWEDVPGTTIESCGNYKDHSLFSAKEWAKLILEQGISDDAFERHVI
                     "
BASE COUNT         1317 a         1046 c          859 g         1324 t
ORIGIN      
        1 cttttacctc ttcctcccta ctcacctgag tacaatccta ttgagaaaac atgggctcat
       61 atcaaaaagc acctcaaaaa ggtattacca agttgcaata ccttttatga ggctcttttg
      121 tcttgttctt gtttcaattg actatattat cagtgtaata gtctaataga tagttaaatg
      181 tagttggatt tccactaaag gttgatgagt aagtttttgt atctgaacct gattggccgc
      241 aagcagctaa aagcaaaaca gatgcaaaag tcaggcctgc actaaggaca cgcttcttta
      301 tgttcatctt ctttctcctt aatagtggga atttgtaaag ttaattgaat ttcgagaatg
      361 aaagtttata aaccttggtt ataaaaaaca aaggatttct gcttttatac agtcctccct
      421 tgtttttata tgatttcaat tttaaatttt tctgcaaaaa atatttatag taattccaca
      481 cagaaagcat cccatggaac taagatttgt ttttcaaaga cttcttgagc tagggtgttt
      541 tcaatcaaga cagatttgac ttttccttct actgtcaagt cttgctcttc attggacaag
      601 ttagccacaa ctaggaagcg acggtcgcca tccttacgta tataagcaaa gaccttatca
      661 gccgtatcaa gcaattcaaa gtcagctcga actagccagc tattctcctt gcgaatttgg
      721 accagtttct gataggtata gaaaatagaa tctggatttg ccagcgcttc ttggacattg
      781 atcatctcgt aatttggatt aaccgccaac caaggttgac ctgttgagaa accagcgttt
      841 ttgctctcgt cccattgcat aggggtacgg gcattgtcac gtccaataac acggatactg
      901 tccatgattt cttcaatcgg aacacctttt tcaagagcct cacgcgcata gttgagagat
      961 tcaatatctt ctacttgatc cagtgtttca aacggatagt tggtcatccc aatctcctca
     1021 ccttggtaga tataaggagt tcctctcata agatgaagca agattgcaaa ggctttggca
     1081 gatttttcgc ggtattcttg gtcatttccc cagattgaga caatacgagg gaggtcatgg
     1141 ttgttccaga agagggaatt ccagccgtcc tcaactccta actctgtctg ccatttgttg
     1201 aagatttctt ttaacttagc gatattcagc tctttttgat agtgccattt aggctgacct
     1261 tcctgatact gaagaccgat atgttcaaac tggaagacca tagacaattc ttgccccttt
     1321 ggatcagagt agagcttggc aatctctggc gttgctcccc aagtctcccc tactgtcaag
     1381 agatccttat ctccaaaggt cgcctgattc atttccttga gatagggatg gagcatagga
     1441 ccattattga ctaccttctc gtcaggaatt ttgccaatca tgtcaataac atccatacgg
     1501 aaaccaccaa tacccttatc aatccagaag ttcatcatct cataaatttt ctggcgaagt
     1561 ttttcatttt cccagttgag atccggctgt ttcttgctga aaaagtggag atagtattga
     1621 cctgactttt catcgtattc ccaagcagac ccactaaaga tagaatctaa atcgttaggc
     1681 tcatcccgcc agatatagta gtctcgctca gggctattag gattttcaca ggcctctaca
     1741 aaccaggcat gctcatccga ggtatgattg accaccaagt ccatgatgat acggatatca
     1801 cgcttcttag cttctgcaat cagctgatcc atgtcctcca tggttccaaa aatagccgca
     1861 atcgcttgat aatcagcaat atcgtagcca ttatcatcca tagggctgtc ataaacggga
     1921 gaaagccaaa ttgctgtgat tcctagcttg gctagatagt ccaacttact ggtaattcct
     1981 ggcaaatcgc caattccatc tccattacta tccataaaac tctttggata gacttgatag
     2041 actacggcat tatgccacca tttttcttgc atctgtttac ctcattattt tcataatcta
     2101 tagtctatga tagcactttt taaaattttg tgcaagcgtt tgcttaatct ttttaatttc
     2161 ttttttagct ccgtagtttc ctaacttcca attttttatt ataatagagt ccagaggtaa
     2221 aaaaatgaaa aaacaagctt ttagttctga acagtatttg aatttacaac gcgaccatat
     2281 tttggagcgc attaaccaat ttgacggcaa gctctactta gagtttggcg gtaaaatgtt
     2341 agaagatttc cacgctgctc gtgtccttcc tggttatgaa cctgacaaca aaatcaagct
     2401 cttgcaagaa ttgaaagagc aggttgaggt tgtgattgcc attaatgcta gcaacattga
     2461 acattccaaa gcacgtggcg acttgggcat ttcttatgac caagaagttc ttcgtttgat
     2521 tgacaaattc aatgaattag ggatttttgt tggttccgtt gtcattacac aatacgctgg
     2581 ccaacccgct gcagatgcct tcctcaacca acttgagaaa aacggaattg attcttatct
     2641 tcattatcca atcaaaggat atccgacgga tatggatcac atcatttccc cagaaggcat
     2701 gggcaaaaac gactacatca aaaccagtcg caacttgatt gtcgtaaccg ctcctggacc
     2761 cggttctgga aaattggcaa cgtgtatgtc caatatgtac cacgaccaaa tcaatggcat
     2821 caagtctggc tacgctaaat ttgaaacctt ccctgtttgg aatcttcccc ttcatcatcc
     2881 agttaacttg gcttatgaag ctgccacagc tgaccttgat gatgtcaaca tgattgaccc
     2941 cttccatctt caaacctatg gagaaaccac tgtcaactac aaccgtgata tcgaaatctt
     3001 cccagtgctc aagcgcatgt tggaacgtat tctcggaaaa tcaccatacg cttcaccgac
     3061 agatatgggt gtcaacatgg ttggtttcgc tattacagat gacgaggctg ctgtcgaagc
     3121 ttctaaacaa gaaatcatcc gccgttacta tcaaacagtt cttgacttca aagctgaaaa
     3181 agttggcgaa gctgccgtca agaaaattga gttgctcatg aacgacctcg gtatctcacc
     3241 tgcagaccgt aaggttgctg tcgttgcgcg ccaaaaagca gaagaaactg gcggaccagc
     3301 cctagctctt gaattaccaa atggtgacat tgtcactggt aaaaactcag aactctttgg
     3361 ccctacagcc gctgccttga tcaacgccat caaaaaatca gctgacatcg ctaaagaagt
     3421 aaaactaatc gagcctgaag ttgttaagcc aatccaagga cttaaaatcg atcatctcgg
     3481 tagccgcaat ccacgccttc attcaaatga aatcctgatt gcacttgcta tcacagctac
     3541 agaaaatcct gatgctgccc gcgctatgga agaactcggc aacctcaaag gaagcgaagc
     3601 ccactcaacc atcatcttga ctgatgaaga caagaatgtc cttcgtaaac tgggtatcaa
     3661 cgtaaccttt gacccatact accaatacga ccgcttatat cgtaagtaaa gatttcaacc
     3721 tctccagcct cggagaggtt ttctctctgt ctcaggagca agctttatga tataatgaga
     3781 gaagaaaact gaaaggattt accatgtcaa aagaagttat tgtcgaaagt tttgaacttg
     3841 accacaccat tgtcaaagca ccctatgttc gcttgattgg ggaagaaaca ggaccaaaag
     3901 gagacatcat ctccaattat gatattcgct tggtgcaacc aaacgaagac tctatcccta
     3961 ctgccggcct tcacactatc gagcacctct tagccaaact catccgtacc cgcattgacg
     4021 gcatgattga ctgttcacca tttggttgcc gcacaggctt ccacatgatt atgtggggac
     4081 gtcacaccag tgctaaaatc gcagctgtta tcaaggattc gctcaaggaa atcgctgaaa
     4141 ctactacttg ggaagatgtc ccagggacaa ccatcgaatc ttgcggaaac tacaaggacc
     4201 acagcctctt ctctgctaaa gaatgggcaa aactcatctt ggaacaaggg atttcagatg
     4261 atgcctttga acgtcatgtg atttaaaatc gagtagggga taatctctag cccctctcac
     4321 accaccgtac gtgccgttcg gcatacggcg gttcaactaa cttttaacgc atgtcgttca
     4381 aggtaataat ccaaacacga aaccaatcca cgtttttcaa ggactggttt tgatatagca
     4441 cgtttaagta ccgacttctg agctactata gtggattgaa actagaatag ttcacctctg
     4501 cttctaaaac attgttagaa atcgatttga ctatcctgat cgattt
//
LOCUS       DAVBBO010000089         4438 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ST1
            SAMEA2066453-rid20184263.denovo.089, whole genome shotgun sequence.
ACCESSION   DAVBBO010000089 DAVBBO010000000
VERSION     DAVBBO010000089.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2066453
            Sequence Read Archive: ERR351777
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 4438)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4438)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980402.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980402.1
            Genome Coverage       :: 176x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:17:33
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,141
            CDSs (total)                      :: 2,104
            Genes (coding)                    :: 1,953
            CDSs (with protein)               :: 1,953
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 16S)
            partial rRNAs                     :: 1 (23S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 151
            CDSs (without protein)            :: 151
            Pseudo Genes (ambiguous residues) :: 0 of 151
            Pseudo Genes (frameshifted)       :: 73 of 151
            Pseudo Genes (incomplete)         :: 76 of 151
            Pseudo Genes (internal stop)      :: 40 of 151
            Pseudo Genes (multiple problems)  :: 32 of 151
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4438
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2066453-rid20184263.denovo.089"
                     /strain="ST1"
                     /db_xref="taxon:1313"
     gene            <1..119
                     /locus_tag="VQU30_002068"
     CDS             <1..119
                     /locus_tag="VQU30_002068"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000032537.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HET2448103.1"
                     /translation="QQGFTDRLVGYSSSIALVFTTLIGMISLVQRRVLKEDD"
     gene            121..966
                     /locus_tag="VQU30_002069"
     CDS             121..966
                     /locus_tag="VQU30_002069"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000819520.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HET2448104.1"
                     /translation="MKRFKPTTILEYILLTLLAGLFLFPMVWMVVSAMKPEADVYKNL
                     TSWQAFLPSLNPADWFKPYQEVFERFSIFTYLGNSIFYAGTFAIGSIIVNALAGFAFA
                     KVNFSGKKILFGFLLALLIIPVETVLIPQFTIINSLGLVNNRLAVIIPGLASVFNIYL
                     FRNFFIAIPEEILESAKMDGASIVRIFFRIMLPMSKPAVATVGVLSFISSWNDYIWPL
                     MVLTDSSKFSMQVAITTINTTQPVYINQVMAVLTISTIPLILVYVVAQKYIVQGLGGS
                     GTGIK"
     gene            976..2295
                     /locus_tag="VQU30_002070"
     CDS             976..2295
                     /locus_tag="VQU30_002070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 32 protein"
                     /protein_id="HET2448105.1"
                     /translation="MINKTFTVEKANRFIAENKHLVNTQYKPEEHFSAEIGWINDPNG
                     FVYFRGEYHLFYQFYPYDSVWGPMHWGHAKSKDLVTWEHLPVALAPDQDYDRNGCFSG
                     SAIVKDDRLWLMYTGHIEEETGVRQVQNMAFSDDGIHFEKISQNPVATGSDLPDELIA
                     ADFRDPKLFEKDGRYYSVVAAKHKDNVGCIVLLGSDNLVEWQFESIFLKGGEHQGFMW
                     ECPDYFELDGKDCLIMSPMRYQREGDSYHNINSSLLFTGKVDWREKRFIPESVQEIDH
                     GQDFYAPQTLLDDQNRRILIAWMQTWGRTLPTHDQEHKWACAMTLPRILRLEDGKLRQ
                     FPVKKGQYQIQIDKDCHYHLGNDTDYLEFGYDSNAQQVYIDRSHLIQKILGEEEQDTS
                     RRYVDIEAKELEVVLDKNSIEIFVNQGEASLTATYYLTVPAELSRID"
     gene            complement(2503..2575)
                     /locus_tag="VQU30_002071"
     tRNA            complement(2503..2575)
                     /locus_tag="VQU30_002071"
                     /product="tRNA-Lys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(2540..2542),aa:Lys,seq:ctt)
     gene            complement(2839..4110)
                     /locus_tag="VQU30_002072"
     CDS             complement(2839..4110)
                     /locus_tag="VQU30_002072"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001113185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication-associated recombination protein A"
                     /protein_id="HET2448106.1"
                     /translation="MPDNLALRMRPKTIDQVIGQEHLVGPGKIIRRMVEANRLSSMIL
                     YGPPGIGKTSIASAIAGTTKYAFRTFNATVDSKKRLQEISEEAKFSGGLVLLLDEIHR
                     LDKTKQDFLLPLLESGLVIMIGATTENPFFSVTPAIRSRVQIFELEPLSNQDVKEALQ
                     IALSNPERGFDFPIELDEDALDFIATSTNGDLRSAFNSLDLAVLSTPENDEGIRHITL
                     DIMENSLQRSYITMDKDGDGHYDVLSALQKSIRGSDVDASLHYAARLIEAGDLPSLAR
                     RLTVIAYEDIGLANPEAQIHTVTALDAAQRIGFPEARILIANVVIDLALSPKSNSAYV
                     AMDKALADLKTSGHLPIPRHLRDGHYSGSKELGNAQDYLYPHNYPGNWIKQDYLPEKI
                     RNHHYFQAEDTGKYERALAQRKEAIDRLRKI"
BASE COUNT         1294 a          809 c          976 g         1359 t
ORIGIN      
        1 atcaacaagg ttttactgat cgtcttgtag gatattctag ctcaatcgct ttagtattta
       61 caacgttaat tggtatgatt agcttagtac aacgtcgcgt tctgaaggag gatgactaag
      121 atgaaacgat ttaaaccaac aacaatctta gaatatattc tgttaacttt attggcagga
      181 ctcttccttt ttcctatggt ttggatggta gtttcagcta tgaagccaga agcggatgtt
      241 tataaaaatt tgactagttg gcaagccttc ttaccaagtt taaatcccgc tgattggttt
      301 aaaccttatc aggaagtatt tgagcgcttt agtattttta catatctagg gaacagcatt
      361 ttttatgctg gaacgtttgc tattggttct attattgtca atgcactggc cggtttcgct
      421 tttgcaaaag tcaatttttc aggtaagaaa attttatttg gtttcttact tgctttactt
      481 attattccag tggaaactgt gttaattcca caatttacca ttatcaattc cttaggtttg
      541 gtcaataatc gtcttgcagt tattattcca ggattggcga gtgtatttaa tatttactta
      601 tttaggaatt tctttattgc aattccagaa gagattcttg agtctgcaaa gatggacgga
      661 gcaagtatcg ttagaatttt ctttagaatt atgcttccaa tgtctaaacc tgcagttgct
      721 acagttggtg ttttatcatt tatttcaagc tggaatgatt atatctggcc attgatggtt
      781 ttgacagatt cttctaaatt ttcaatgcag gttgcaatta caactattaa tacaactcaa
      841 ccagtttata tcaatcaggt aatggctgta ttaactattt caacgattcc gttgattttg
      901 gtctatgtag tcgctcagaa atatattgtt caaggtctgg gtggttccgg aactggaata
      961 aaataggata tacttatgat aaataaaaca tttacagtag aaaaagccaa tcgttttata
     1021 gcagaaaata aacatctcgt taatactcaa tataagcctg aagaacattt ttcagctgag
     1081 attggttgga tcaatgatcc aaatggattt gtctattttc gtggagaata ccatctcttt
     1141 tatcaattct atccatatga tagtgtttgg gggcctatgc actggggaca tgctaaaagt
     1201 aaggacttgg tgacttggga gcacttgcca gtggcacttg ctcctgacca agattatgac
     1261 cgaaatggtt gtttctcagg ctctgccatt gtcaaggatg atcgcctctg gctcatgtac
     1321 actggacata tcgaagaaga aaccggtgtc cgccaagtgc aaaatatggc attttcagat
     1381 gacgggattc actttgaaaa gatttcccaa aatccagttg caactggatc agacttgcca
     1441 gatgagttga ttgctgctga tttccgtgat ccaaaactct ttgaaaaaga tggacgctat
     1501 tactccgtag tagctgccaa acacaaggat aatgtgggct gtatcgttct actagggtcc
     1561 gataacctag tagaatggca gttcgaatcc atctttttaa aaggaggaga acaccaaggc
     1621 tttatgtggg aatgcccaga ttacttcgag ttagatggga aagattgcct tattatgtca
     1681 cccatgcgtt atcagcgtga gggagactca tatcataaca tcaactcatc gcttttgttc
     1741 acgggtaagg tagattggag agaaaaacgt tttatcccag aatcagttca agaaattgat
     1801 catggccaag acttctatgc gcctcaaaca ttgttggacg atcaaaatcg tcgtatcctg
     1861 attgcttgga tgcagacatg ggggcgtacc cttccaaccc atgaccaaga acacaaatgg
     1921 gcatgtgcca tgactttacc tagaattcta agattggaag atggcaaact aagacaattc
     1981 cctgttaaaa aaggccaata tcaaatccaa atagataaag attgtcatta ccacttagga
     2041 aatgatacag attatcttga atttggttat gacagtaatg cgcagcaagt ttacattgat
     2101 cgtagccatc ttattcaaaa aattctaggt gaagaagaac aggacactag tcgacggtat
     2161 gtagatattg aagctaaaga attggaagtt gttctagata aaaattccat cgagattttt
     2221 gtcaatcaag gtgaagcaag cttgactgca acttattact taacggtgcc agctgagcta
     2281 tcacgaattg attaaaaatt aagttatttc tcctaaagaa aaagttctct ttctaaaata
     2341 gtggaaagag gactttttgt gttttgggta tataagctta gtttatggta tttgtaaaat
     2401 tggtgttgga ttatgattta agctagtttt ctaaagaatt tgaaaaaaat tttatttaag
     2461 caaaaaaacc ttggttccaa ggcttttcct gttgtattta gatgccccct acagggatcg
     2521 aacctgtgac ccacggatta agagtccgct gctctgccag ctgagctaag gaggcaaaga
     2581 aaaagctgta ttggtgccga aacttcacgg tttgtattga acccgcgcaa ttaagcaggt
     2641 gggcaactcg ctctaactga agctgtttcc gtgtgagacg gcctacatgc tgttagaaga
     2701 cttttgtttc cctaataata caaaaaatag tcggtcaaca cttaagtgtg aagtcgtaca
     2761 ccacagcgtt tctatactta tatgatacca ctttttcaaa aaaaatcaag aggaaagtgc
     2821 aattttttga aaaggatttc agatttttcg caaacgatcg atagcttcct ttctttgagc
     2881 caaagcccgt tcatatttac cagtatcttc tgcttggaaa tagtgatgat tacgaatttt
     2941 ttctggcaga tagtcttgct tgatccaatt tccaggatag ttgtgtggat agagatagtc
     3001 ttgggcattc cccagttcct tgcttccact gtagtgccca tcacgcaggt gtcgcggaat
     3061 aggcaagtgc cctgatgttt tgaggtcagc aagtgcctta tccatagcta cataggctga
     3121 gttggatttt ggagaaaggg ccaaatcaat cacgacattg gcaatgagaa tgcgggcttc
     3181 ggggaaacca atcctttgtg cagcatccag agcagtcacg gtatgaatct gggcctcagg
     3241 attggctaag ccaatatctt cataggcgat aacagtcaag cgacgagcga gactaggcag
     3301 atccccagcc tcaatcaagc gggcagcata gtggagactg gcatccacat ctgagccacg
     3361 gatagacttt tgcagggcag atagaacatc atagtgaccg tctccatcct tgtccatagt
     3421 gatgtagctt ctctgaagac tattttccat gatgtctaag gtgatgtggc gaatgccctc
     3481 gtcattctca ggggtagaga gaacagccaa gtccagtgag ttaaaggcag agcgaaggtc
     3541 tccgtttgta gaggttgcga tgaaatccag cgcatcctca tctagttcta ttggaaaatc
     3601 aaaaccacgt tcagggttac ttagagctat ctgcagggcc tctttgacgt cttggttaga
     3661 cagaggttcc aactcgaaaa tttgaacacg gctacgaatg gcaggagtga cagagaagaa
     3721 aggattttca gtcgttgctc caatcatgat gaccagtcca ctttccaaga gaggcaagag
     3781 gaagtcttgc ttggtcttat ctagtcgatg aatttcgtct agcaatagga cgagaccacc
     3841 agaaaattta gcttcttccg agatttcttg cagtcgcttt ttactatcaa ctgtcgcatt
     3901 gaaagttcga aaggcatact tggtcgttcc agcgatggca gaggcaatac tggttttgcc
     3961 gattccagga gggccatata gaatcatgga ggacaggcgg ttggcttcca ccatgcggcg
     4021 gatgattttt ccaggtccga ccagatgctc ctgaccgatg acctggtcga tggttttagg
     4081 gcgcatgcga agcgcgagat tgtctggcat agcagtcctt tctaacgtgg atttgagtag
     4141 aatgactcat ctactatatc ttactatgtc cattctagcc tattagttgt gatatttcaa
     4201 tggttttgta ataatcaggg agtgagatag aatctttttt actatttaat ttaatgagga
     4261 gaggtatcag catgagagat ttgattttcc ttaaagctca aaataggata gttgagccta
     4321 aagaagtgga agtgctgact tgagaaataa tattgctgaa tgtcattgta tgaactataa
     4381 tgaaaagaga ggtgataagc aatggaaatg atggaccaag tcaggaaatt ttgatttt
//
LOCUS       DAVBBO010000090         4116 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ST1
            SAMEA2066453-rid20184263.denovo.090, whole genome shotgun sequence.
ACCESSION   DAVBBO010000090 DAVBBO010000000
VERSION     DAVBBO010000090.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2066453
            Sequence Read Archive: ERR351777
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 4116)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4116)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980402.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980402.1
            Genome Coverage       :: 176x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:17:33
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,141
            CDSs (total)                      :: 2,104
            Genes (coding)                    :: 1,953
            CDSs (with protein)               :: 1,953
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 16S)
            partial rRNAs                     :: 1 (23S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 151
            CDSs (without protein)            :: 151
            Pseudo Genes (ambiguous residues) :: 0 of 151
            Pseudo Genes (frameshifted)       :: 73 of 151
            Pseudo Genes (incomplete)         :: 76 of 151
            Pseudo Genes (internal stop)      :: 40 of 151
            Pseudo Genes (multiple problems)  :: 32 of 151
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4116
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2066453-rid20184263.denovo.090"
                     /strain="ST1"
                     /db_xref="taxon:1313"
     gene            <1..776
                     /locus_tag="VQU30_002073"
     CDS             <1..776
                     /locus_tag="VQU30_002073"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000603792.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2448107.1"
                     /translation="DYSIVEEKLDWQSKLSKIYPNVEFIKIEKLKLILLCKYRNQIID
                     LEDDKKRLLLLKLLYLTSKQFCYDEFKGAKFGCMSFFSHYQGYMSRLDSLDSDKFVSV
                     KQRIVSSISKLVEQYSDHIINLDRTLVDSLSDTLENQLFDDWDYILSEITTYSELLAK
                     SGLLYNSLDYKIDNVKKEVAKLSDFHQSLFKIEGFSDFFDSWQFQRYRSLVNQVYEIF
                     SMLQVSSVERTVLCGALSTIVFSKSNFNYQAFFEYLKDT"
     gene            805..1713
                     /locus_tag="VQU30_002074"
     CDS             805..1713
                     /locus_tag="VQU30_002074"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000386786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2448108.1"
                     /translation="MDYVDVILDEYGSVFLIKDHIKLKINNLELYRYFSSFGMSHLQF
                     RKEELPGKLKQFDFEKNKSDSYFSKKSSLIDFIKRNYFYDIKLYSDNPKNPIESWKNK
                     TEKIKIAKSTEILWSEVANFSSISKSPYYCLLYNLKNTENYILIISKTYFSAIQKMVS
                     YNLNNYFELEDVCCKSIVSKRELIENSININKSKMKLLNVCEGSKGYTRRVFKYNNIF
                     VGQLEFHSNIIFSEIALNELSIVKLLDSVESVLSEQLFGKLNWDNLFVVLSDDFNDYL
                     DINESQKYYSNGSLRGLELGIFMGGV"
     gene            1715..3613
                     /locus_tag="VQU30_002075"
     CDS             1715..3613
                     /locus_tag="VQU30_002075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YcaO-like family protein"
                     /protein_id="HET2448109.1"
                     /translation="MRIIEIVDVEDQLLQLLSAHTNIDIRAQELSTLDPDSKVDLIIY
                     LKSRRDIENINNIIIKSPNRNIIVIISAFDIIYALYFPKSTFRPCLNCLLLKLKDNNP
                     EHNLLLFLKYGTLPSKHFNLDNRLKSNLILFNEKLDPKVEEYSIEGVNTTNFTFHFSC
                     SCENSGYDMSERMADILLGEGKKLSPKNYRLKKSEHLFDFTRYLDRNFGFFHHSYDEK
                     ISEYAPLHAVEINVDAGYESGWGRTFMTEAATKSAFLESLERYCNSRNRRYKKLIRGC
                     FSDLSKKYNTLNPVDFCLSNKEYRDSSYKFHDFDSEKNYDWIFGKNITTGKICLLPSQ
                     LVFYKDFSKSEENERFVYETSNGCALGSSIEEAIFYGILEIIERDNFLLTWYLKEEVK
                     QLSWESLPSRLRIINERLKEDNCELKLFNITKEVGIPVIWALYINHNENASIRSFSAA
                     GCHINPLSAIESAIFEVITSVPTFERLIEVRNKESFIEEIQNNFSLIRDIDDHILYHA
                     HADYKNKMPFLFKNNYSEYQNEFDENRIFNTYSHATLTSDLQALIKIIEKKFGDIYVV
                     NISDKVSEKFGLYCVKVLIPGLLNMSFGHSNRRVNIERIKNYVDYRGGNVNSITLNSI
                     NHLPHPFP"
     gene            3637..>4116
                     /locus_tag="VQU30_002076"
     CDS             3637..>4116
                     /locus_tag="VQU30_002076"
                     /inference="COORDINATES: protein motif:HMM:NF025394.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiopeptide-type bacteriocin biosynthesis
                     protein"
                     /protein_id="HET2448110.1"
                     /translation="MKRDWKSKHLFYHDVQQFDKLVIYLSKFMDKLVNQNQIEKYFYI
                     RYWEGGPHIRLRYLVRDTQNFETIDSMINKYAYKFWENNPPMKLLNKTDYKKIYNESI
                     DNNGKMDRKLRKNATIENIAYIPEIERYGGEEALIVSEDLFCICSQVSTALLNVVDNY
                     "
BASE COUNT         1539 a          443 c          712 g         1422 t
ORIGIN      
        1 cagattactc aatagtggaa gaaaaattag attggcaaag taaattatct aaaatttatc
       61 cgaatgttga atttataaaa attgaaaaat taaaattgat tttgttgtgt aaatatagaa
      121 atcaaattat tgacttagag gatgataaaa aaagattgtt actattgaaa ttattatatt
      181 tgacttcaaa gcaattttgc tatgatgaat ttaaaggagc gaaatttgga tgtatgtcat
      241 ttttttcaca ttatcaaggt tatatgagca gattagattc actcgactca gataaatttg
      301 tttcggttaa acagaggatt gtttcctcta tttctaaatt agttgagcaa tattcagatc
      361 atattataaa tctggataga actttagttg attctctaag tgataccctt gagaatcagc
      421 tatttgatga ttgggattat atattaagcg aaataactac atatagcgaa ttattagcaa
      481 aatcaggatt gttatataat tcgctagact ataagattga taatgtaaaa aaagaagtgg
      541 ccaagctaag tgactttcac caatctttat ttaaaattga aggattttca gatttttttg
      601 atagttggca atttcaaaga tataggtctc tcgtgaacca agtttatgaa attttttcaa
      661 tgttacaagt aagtagtgta gaaagaactg tgttgtgcgg agctctaagt actattgtct
      721 ttagtaagtc aaattttaac tatcaagctt tttttgagta tctaaaagat acgtagaatt
      781 cgattttaaa ggaggctgaa atatatggat tatgtagatg taatattgga tgagtatggg
      841 agtgtttttc tgataaagga tcacataaaa ctaaaaatta ataatctaga actatatcgg
      901 tattttagta gctttggaat gagtcatctt caatttagaa aagaagagct tccaggaaaa
      961 ttaaagcagt ttgattttga aaaaaataaa agtgacagtt atttttctaa gaaaagtagt
     1021 ctgattgatt ttattaagag aaattatttt tatgatatta agttatattc tgataatccg
     1081 aaaaatccga tagagtcttg gaaaaataag acagaaaaaa ttaagattgc taaaagtaca
     1141 gaaattcttt ggagtgaagt agcaaatttt tcgtcaattt ctaaatctcc ttactattgc
     1201 ttgttatata atttaaagaa tactgaaaat tacatattga taatcagtaa gacatatttt
     1261 tcagccatcc aaaaaatggt ttcgtataat ctaaataatt attttgaatt agaagatgtt
     1321 tgttgtaaaa gcatagtgag caagcgagaa ttgatagaaa attcaattaa tattaacaaa
     1381 agcaaaatga aactgctaaa tgtttgcgaa ggtagtaaag gttacacaag aagagtattt
     1441 aagtacaata atatttttgt gggacaattg gaatttcact ctaacataat cttttcagaa
     1501 attgctttaa atgaattaag tattgttaag cttttagatt ctgttgaaag tgttttatct
     1561 gagcaactat ttggaaaatt aaattgggat aatttatttg ttgttttatc agatgatttt
     1621 aatgattatc tggatataaa tgaatctcaa aaatactact caaatggttc tttgagagga
     1681 ctggagcttg gaatctttat gggaggggtt taaaatgaga ataattgaaa ttgttgatgt
     1741 tgaggaccaa cttttacaac ttttaagtgc acataccaat attgatatta gagcacaaga
     1801 gttatcaaca cttgacccag attcaaaagt tgatttgatc atatacttga aatctcgacg
     1861 tgatattgaa aacataaata atattattat taaatcacct aacaggaata tcattgttat
     1921 aataagtgct tttgatatta tatatgcatt gtattttcca aaatcaacat ttagaccttg
     1981 tttgaactgt ctattattaa aacttaaaga taacaaccct gagcataatc tattattatt
     2041 cctgaaatac ggaacattac ctagtaaaca ttttaatctt gataataggt taaaatcaaa
     2101 tttaatacta tttaatgaga agttagaccc taaggtagag gagtatagta ttgagggggt
     2161 aaatactaca aattttactt tccattttag ttgtagctgt gaaaatagtg gttacgatat
     2221 gtcggaaaga atggcagata ttctacttgg tgaaggaaaa aaattatctc ctaaaaatta
     2281 tcgtttaaaa aagagtgagc atctattcga ttttactaga tatctagata gaaattttgg
     2341 attttttcat cattcatatg atgaaaaaat ctccgaatat gcgcctctcc atgcagtaga
     2401 gattaatgtt gatgctggtt acgagtcagg ctggggaagg acttttatga cagaggctgc
     2461 aacaaaatct gcttttttag agtcattaga gagatactgc aactctagaa atagacgcta
     2521 taaaaaatta attagagggt gtttttctga tttatctaaa aagtacaata cattaaatcc
     2581 tgttgatttt tgtctttcta ataaagaata tagagatagt tcctataaat ttcatgattt
     2641 tgattctgag aaaaattatg attggatatt tggtaaaaat ataactaccg gaaaaatttg
     2701 cttattgccc tcgcaactag tattttataa agactttagt aaaagcgaag aaaatgaaag
     2761 gtttgtttat gaaacatcaa atggatgtgc tttggggagt agtattgagg aagctatttt
     2821 ttatgggatt ttagagatta ttgaaagaga taatttttta cttacatggt atttaaaaga
     2881 agaagtaaaa caattatcat gggaatcttt accatctcgc ctacgtatta ttaatgaaag
     2941 actaaaagaa gataactgtg agctcaaact ttttaatata actaaagaag tgggcatacc
     3001 agtaatttgg gcattgtata taaatcataa tgaaaatgct agtattcgaa gtttttcagc
     3061 tgcaggctgt catattaatc ctttaagtgc aattgaatca gcaatttttg aagtaataac
     3121 ttctgtgcca acttttgaaa gattaattga agttagaaat aaagagtcat ttattgagga
     3181 aattcagaat aatttttctt taatacgaga tattgacgat catatattgt atcatgctca
     3241 tgcggattat aaaaataaaa tgcccttttt atttaaaaat aattatagtg aatatcaaaa
     3301 tgaatttgat gagaatagaa tttttaatac ttattcacat gcaacgctta catcagattt
     3361 acaggcacta ataaaaatta ttgaaaaaaa atttggagat atatatgtag tgaatataag
     3421 tgataaagtt tccgaaaaat ttggacttta ttgtgttaaa gtgttgattc ctggacttct
     3481 taatatgtca tttggacatt caaatcggcg tgtaaatata gagaggataa aaaattatgt
     3541 agattataga gggggaaatg taaatagtat tacattgaat tccataaacc atcttcccca
     3601 tccatttcca taagattata tataaaggaa taataaatga aaagagattg gaaatcaaag
     3661 catttatttt atcatgatgt tcaacaattt gataaattgg taatctattt atcaaaattt
     3721 atggataaat tagttaatca gaatcagatt gaaaaatatt tctatattcg ttattgggaa
     3781 ggggggcctc atattcgatt aagatatttg gtgagggata cacaaaattt tgaaacaatt
     3841 gatagtatga taaataagta tgcttataaa ttttgggaaa ataatcctcc aatgaagtta
     3901 ttaaataaga ccgattataa gaaaatttat aatgagagta ttgataacaa cggaaagatg
     3961 gatagaaaat tgaggaaaaa tgcgactatt gaaaacattg cctatatacc ggaaatagag
     4021 agatatggcg gggaagaagc tctgatagta agcgaagatc tattttgtat ctgtagtcag
     4081 gtttcaactg cgttacttaa tgtggtagat aactat
//
LOCUS       DAVBBO010000091         3987 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ST1
            SAMEA2066453-rid20184263.denovo.091, whole genome shotgun sequence.
ACCESSION   DAVBBO010000091 DAVBBO010000000
VERSION     DAVBBO010000091.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2066453
            Sequence Read Archive: ERR351777
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 3987)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3987)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980402.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980402.1
            Genome Coverage       :: 176x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:17:33
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,141
            CDSs (total)                      :: 2,104
            Genes (coding)                    :: 1,953
            CDSs (with protein)               :: 1,953
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 16S)
            partial rRNAs                     :: 1 (23S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 151
            CDSs (without protein)            :: 151
            Pseudo Genes (ambiguous residues) :: 0 of 151
            Pseudo Genes (frameshifted)       :: 73 of 151
            Pseudo Genes (incomplete)         :: 76 of 151
            Pseudo Genes (internal stop)      :: 40 of 151
            Pseudo Genes (multiple problems)  :: 32 of 151
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3987
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2066453-rid20184263.denovo.091"
                     /strain="ST1"
                     /db_xref="taxon:1313"
     gene            <1..2253
                     /gene="phtA"
                     /locus_tag="VQU30_002077"
     CDS             <1..2253
                     /gene="phtA"
                     /locus_tag="VQU30_002077"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000700436.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pneumococcal histidine triad protein PhtA"
                     /protein_id="HET2448111.1"
                     /translation="EQIVIKITDQGYVTSHGDHYHYYNGKVPYDAIFSEELLMKDPNY
                     KLKDEDIVNEVKGGYVIKVDGKYYVYLKDAAHADNVRTKEEINRQKQEHSQHREGGTP
                     RNDGAVALARSQGRYTTDDGYIFNASDIIEDTGDAYIVPHGDHYHYIPKNELSASELA
                     AAEAFLSGRGNLSNSRTYRRQNSDNTSRTNWVPSVSNPGTTNTNTSNNSNTNSQASQS
                     NDIDSLLKQLYKLPLSQRHVESDGLVFDPAQITSRTARGVAVPHGDHYHFIPYSQMSE
                     LEERIARIIPLRYRSNHWVPDSRPEQPSPQPTPEPSPGPQPAPNLKIDSNSSLVSQLV
                     RKVGEGYVFEEKGISRYVFAKDLPSETVKNLESKLSKQESVSHTLTAKKENVAPRDQE
                     FYDKAYNLLTEAHKALFENKGRNSDFQALDKLLERLNDESTNKEKLVDDLLAFLAPIT
                     HPERLGKPNSQIEYTEDEVRIAQLADKYTTSDGYIFDEHDIISDEGDAYVTPHMGHSH
                     WIGKDSLSDKEKVAAQAYTKEKGILPPSPDADVKANPTGDSAAAIYNRVKGEKRIPLV
                     RLPYMVEHTVEVKNGNLIIPHKDHYHNIKFAWFDDHTYKAPNGYTLEDLFATIKYYVE
                     HPDERPHSNDGWGNASEHVLGKKDHSEDPNKNFKADEEPVEETPAEPEVPQVETEKVE
                     AQLKEAEVLLAKVTDSSLKANATETLAGLRNNLTLQIMDNNSIMAEAEKLLALLKGSN
                     PSSVSKEKIN"
     gene            2411..>3987
                     /locus_tag="VQU30_002078"
     CDS             2411..>3987
                     /locus_tag="VQU30_002078"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000700436.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pneumococcal-type histidine triad protein"
                     /protein_id="HET2448112.1"
                     /translation="MKINKKYLAGSVATLVLSVCAYELGLHQAQTVKENNRVSYIDGK
                     QATQKTENLTPDEVSKREGINAEQIVIKITDQGYVTSHGDHYHYYNGKVPYDAIISEE
                     LLMKDPNYQLKDEDIISEIKGGYVIKVDGKYYVYLKDAAHADNVRTKEEINRQKQEHS
                     QHREGGTSTNDGAVAFARSQGRYTTDDGYIFNASDIIEDTGDAYIVPHGDHYHYIPKN
                     ELSASELAAAEAFLSGRGNLSNSRTYRRQNSDNTSRTNWLPSVSNPGTTNTNTSNNSN
                     TNSQASQSNDIDSLLKQLYKLPLSQRHVESDGLVFDPAQITSRTARGVAVPHGNHYHF
                     IPYEQMSELEKRIARIIPLRYRSNHWVPDSRPEQPSPQSTPEPSPSLQPAPNPQPAPS
                     NPIDEKLVKEAVRKVGDGYVFEENGVSRYIPAKDLSAETAAGIDSKLAKQESLSHKLG
                     AKKTDLPSSDREFYNKTYDLLARIHQDLLDNKGRQVDFEALDNLLERLKDVSSDKVKL
                     VDDILAFLAPIRHPERLG"
BASE COUNT         1374 a          779 c          803 g         1031 t
ORIGIN      
        1 gagcaaatcg tcatcaagat aacagaccaa ggctatgtca cttcacatgg cgaccactat
       61 cattattaca atggtaaggt tccttatgat gcgattttca gtgaagaatt actcatgaaa
      121 gatccaaact ataagctaaa agatgaggat attgttaatg aggtcaaggg tggatatgtt
      181 atcaaggtag atggaaaata ctatgtttac cttaaggatg ctgcccacgc ggataacgtc
      241 cgtacaaaag aggaaatcaa tcgacaaaaa caagaacata gtcaacatcg tgaaggtggg
      301 actccaagaa acgatggtgc tgttgccttg gcacgttcgc aaggacgcta tactacagat
      361 gatggttata tctttaatgc ttctgatatc atagaggata ctggtgatgc ttatatcgtt
      421 cctcatggag atcattacca ttacattcct aagaatgagt tatcagctag cgagttggct
      481 gctgcagaag ccttcctatc tggtcgggga aatctgtcaa attcaagaac ctatcgccga
      541 caaaatagcg ataacacttc aagaacaaac tgggtacctt ctgtaagcaa tccaggaact
      601 acaaatacta acacaagcaa caacagcaac actaacagtc aagcaagtca aagtaatgac
      661 attgatagtc tcttgaaaca gctctacaaa ctgcctttga gtcaacgaca tgtagaatct
      721 gatggccttg ttttcgaccc agcgcaaatc acaagtcgaa cagctagagg tgttgcagtg
      781 ccacacggag atcattacca cttcatccct tactctcaaa tgtctgaatt ggaagaacga
      841 atcgctcgta ttattcccct tcgttatcgt tcaaaccatt gggtaccaga ttcaaggcca
      901 gaacaaccaa gtccacaacc gactccggaa cctagtccag gcccgcaacc tgcaccaaat
      961 cttaaaatag actcaaattc ttctttggtt agtcagctgg tacgaaaagt tggggaagga
     1021 tatgtattcg aagaaaaggg catctctcgt tatgtctttg cgaaagattt accatctgaa
     1081 actgttaaaa atcttgaaag taagttatca aaacaagaga gtgtttcaca cactttaact
     1141 gctaaaaaag aaaatgttgc tcctcgtgac caagaatttt atgataaagc atataatctg
     1201 ttaactgagg ctcataaagc cttgtttgaa aataagggtc gtaattctga tttccaagcc
     1261 ttagacaaat tattagaacg cttgaatgat gaatcgacta ataaagaaaa attggtagat
     1321 gatttattgg cattcctagc accaattacc catccagagc gacttggcaa gccaaattct
     1381 caaattgagt atactgaaga cgaagttcgt attgctcaat tagctgataa gtatacaacg
     1441 tcagatggtt acatttttga tgaacatgat ataatcagtg atgaaggaga tgcatatgta
     1501 acgcctcata tgggccatag tcactggatt ggaaaagata gcctttctga taaggaaaaa
     1561 gttgcagctc aagcctatac taaagaaaaa ggtatcctac ctccatctcc agacgcagat
     1621 gttaaagcaa atccaactgg agatagtgca gcagctattt acaatcgtgt gaaaggggaa
     1681 aaacgaattc cactcgttcg acttccatat atggttgagc atacagttga ggttaaaaac
     1741 ggtaatttga ttattcctca taaggatcat taccataata ttaaatttgc ttggtttgat
     1801 gatcacacat acaaagctcc aaatggctat accttggaag atttgtttgc gacgattaag
     1861 tactacgtag aacaccctga cgaacgtcca cattctaatg atggatgggg caatgccagt
     1921 gagcatgtgt taggcaagaa agaccacagt gaagatccaa ataagaactt caaagcggat
     1981 gaagagccag tagaggaaac acctgctgag ccagaagtcc ctcaagtaga gactgaaaaa
     2041 gtagaagccc aactcaaaga agcagaagtt ttgcttgcga aagtaacgga ttctagtctg
     2101 aaagccaatg caacagaaac tctagctggt ttacgaaata atttgactct tcaaattatg
     2161 gataacaata gtatcatggc agaagcagaa aaattacttg cgttgttaaa aggaagtaat
     2221 ccttcatctg taagtaagga aaaaataaac taatgaaaaa tgaaagtctc gataaagagg
     2281 ctttcatttt tattatgtat atatgtaaaa ttcttgacaa gcaatattaa aaagagtaaa
     2341 ctattaacta gttaattaac cggtttgtta ctttatagtg aatcaaatat acttaagaaa
     2401 agaggaaaga atgaaaatca ataaaaaata tctagctggg tcagtagcta cacttgtttt
     2461 aagtgtctgt gcttatgaac taggtttgca tcaagctcaa actgtaaaag aaaataatcg
     2521 tgtttcctat atagatggaa aacaagcgac gcaaaaaacg gagaatttga ctcctgatga
     2581 ggttagcaag cgtgaaggaa tcaatgccga acaaatcgtc atcaagataa cagaccaagg
     2641 ctatgtcact tcacatgggg accactatca ttattacaat ggtaaggttc cttatgacgc
     2701 tatcatcagt gaagaattgc tgatgaagga tccaaactac cagctaaagg acgaggatat
     2761 tatcagtgaa atcaagggtg gttatgtgat taaggtagat ggaaaatact atgtttacct
     2821 taaggatgca gctcatgcgg ataatgtccg tacaaaagaa gaaatcaatc ggcaaaaaca
     2881 agaacatagt cagcatcgtg aaggagggac ttcaacaaac gatggtgcgg tagcctttgc
     2941 acgttcacaa ggacgctata ctacagatga tggttatatc tttaatgctt ctgatatcat
     3001 tgaggacacg ggtgatgctt atatcgttcc tcacggcgac cattaccatt acattcctaa
     3061 gaatgagtta tcagctagcg agttagctgc tgcagaagcc ttcctatctg gtcggggaaa
     3121 tctgtcaaat tcaagaacct atcgccgaca aaatagcgat aacacttcaa gaacaaactg
     3181 gctaccttct gtaagcaatc caggaactac aaatactaac acaagcaaca acagcaacac
     3241 taacagtcaa gcaagtcaaa gtaatgacat tgatagtctc ttgaaacagc tctacaaact
     3301 gcctttgagt caacgccatg tagaatctga tggccttgtt ttcgacccag cgcaaatcac
     3361 aagtcgaacc gccagaggtg tagctgtccc tcatggtaac cattaccact ttatccctta
     3421 tgaacaaatg tctgaattgg aaaaacgaat tgctcgtatt attccccttc gttatcgttc
     3481 aaaccattgg gtaccagatt caagaccaga acaaccaagt ccacaatcga ctccggaacc
     3541 tagtccaagt ctgcaacctg caccaaatcc tcaaccagct ccaagcaatc caattgatga
     3601 gaaattggtc aaagaagctg ttcgaaaagt aggcgatggt tatgtctttg aggagaatgg
     3661 agtttctcgt tatatcccag ccaaggatct ttcagcagaa acagcagcag gcattgatag
     3721 caaactggcc aagcaggaaa gtttatcgca taagctagga gctaagaaaa ctgacctccc
     3781 atctagtgat agagaatttt acaataagac ttatgactta ctagcaagaa ttcaccaaga
     3841 tttacttgat aataaaggtc gacaagttga ttttgaggct ttggataacc tgttggaacg
     3901 actcaaggat gtctcaagtg ataaagtcaa gttagtggat gatattcttg ccttcttagc
     3961 tccgattcgt catccagaac gtttagg
//
LOCUS       DAVBBO010000092         3589 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ST1
            SAMEA2066453-rid20184263.denovo.092, whole genome shotgun sequence.
ACCESSION   DAVBBO010000092 DAVBBO010000000
VERSION     DAVBBO010000092.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2066453
            Sequence Read Archive: ERR351777
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 3589)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3589)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980402.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980402.1
            Genome Coverage       :: 176x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:17:33
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,141
            CDSs (total)                      :: 2,104
            Genes (coding)                    :: 1,953
            CDSs (with protein)               :: 1,953
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 16S)
            partial rRNAs                     :: 1 (23S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 151
            CDSs (without protein)            :: 151
            Pseudo Genes (ambiguous residues) :: 0 of 151
            Pseudo Genes (frameshifted)       :: 73 of 151
            Pseudo Genes (incomplete)         :: 76 of 151
            Pseudo Genes (internal stop)      :: 40 of 151
            Pseudo Genes (multiple problems)  :: 32 of 151
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3589
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2066453-rid20184263.denovo.092"
                     /strain="ST1"
                     /db_xref="taxon:1313"
     gene            complement(1..396)
                     /locus_tag="VQU30_002079"
                     /pseudo
     CDS             complement(1..396)
                     /locus_tag="VQU30_002079"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611577.1"
                     /note="frameshifted; internal stop; incomplete; missing
                     C-terminus; Derived by automated computational analysis
                     using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            737..2083
                     /gene="gdhA"
                     /locus_tag="VQU30_002080"
     CDS             737..2083
                     /gene="gdhA"
                     /locus_tag="VQU30_002080"
                     /EC_number="1.4.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001858584.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-specific glutamate dehydrogenase"
                     /protein_id="HET2448113.1"
                     /translation="MTSAKEYIQSVFETVKARNGHEAEFLQAVEEFFNTLEPVFEKHP
                     EYIEENILARITEPERVVSFRVPWVDRDGKIQVNRGYRVQFNSAVGPYKGGLRFHPTV
                     NQGILKFLGFEQIFKNVLTGLPIGGGKGGSDFDPKGKTDAEVMRFCQSFMTELQKHIG
                     PSLDVPAGDIGVGGREIGYLYGQYKRLNQFDAGVLTGKPLGFGGSLIRPEATGYGLVY
                     YTEEMLKANGNSFAGKKVVISGSGNVAQYALQKATELGATVISVSDSNGYVIDENGID
                     FDLLVDVKEKRRARLTEYAAEKATATYHEGTVWTYAGNYDIALPCATQNEINGEAAKR
                     LVAQGVICVSEGANMPSDLDAIKVYKENGIFYGPAKAANAGGVAVSALEMSQNSLRLS
                     WTREEVDGRLKDIMTNIFNTAKTTSETYGLDKDYLAGANIAAFENVANAMIAQGIV"
     gene            complement(2589..2759)
                     /locus_tag="VQU30_002081"
     CDS             complement(2589..2759)
                     /locus_tag="VQU30_002081"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000711941.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2448114.1"
                     /translation="MKKENEYVILTIASLGVMIGIVFAIFLDFPVEYGISLGLLNGIV
                     LGSLIVYKNNKN"
     gene            complement(2772..3350)
                     /locus_tag="VQU30_002082"
                     /pseudo
     CDS             complement(2772..3350)
                     /locus_tag="VQU30_002082"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000151458.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
     gene            complement(3367..>3589)
                     /locus_tag="VQU30_002083"
     CDS             complement(3367..>3589)
                     /locus_tag="VQU30_002083"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HET2448115.1"
                     /translation="QAQTPRKSSKLKPLTAEDKACNHVLSKERSKVENIFAKVKTLKM
                     FSTTYRNHRKRFGLRMNLIVGIINHELGF"
BASE COUNT         1109 a          664 c          606 g         1210 t
ORIGIN      
        1 tataagcctg aaataaggca tcaattgtaa caaattctcc tgcctctgca gccttcaaat
       61 ggcgggcaag aaaggctttc tcttcctcaa ctgtcatata tgcatggtta cgaccaccac
      121 gtgtttcttg aaggagagag tcgagtccga actcctcata ttttttacat ttcgccaaat
      181 cgttgtttga ttacagtcta tagtgtattg aatctataat agtacacctc tacttctaaa
      241 acattgttag aaatcgattt gactgtccta atcgatttgt cctgttcttg tttcatttta
      301 ctatagaacg atttgaaggc gtttatgata tttagctgta cgagagtctt ttaaaagtgt
      361 tttgatggct tggatttctt ctttagttga tttcatatca ctattatata atgatttttg
      421 attttagtct ggtataaata ttgctttcct ccaaaatggt cataatttta ctagcaaatc
      481 taacatatca cggataaatt aacaagtgat ttctgaattg ctaaacattt tcttttctta
      541 tagcatacca tactttaaga ttttgtcttt gagaaagata tttccaagaa aaacgttcgt
      601 ttttttatct attttcaaaa aaaccaaaaa ctgaattgaa agaattttta gaaaatttct
      661 gttttttctt tacagtgaaa aaaaattctg ctataatgtc ttatgtaata aaatatgaca
      721 ataaaaggag aacgatatga catctgctaa agaatatatc caaagcgtgt ttgaaactgt
      781 gaaagctcgt aacgggcacg aggctgaatt cctccaagct gttgaagaat ttttcaacac
      841 tttagaacct gtatttgaaa aacaccctga gtatatcgaa gaaaatatct tggcacgtat
      901 tactgagcct gagcgcgtgg tttctttccg tgttccttgg gttgaccgtg atggaaaaat
      961 tcaagtaaac cgtggttacc gtgttcaatt caactcagct gttggaccat acaaaggtgg
     1021 acttcgtttc cacccaactg taaaccaagg gatcttgaaa ttcctcggat ttgaacaaat
     1081 ctttaaaaat gtcttgactg gacttcctat cggtggaggt aaaggtggat cagacttcga
     1141 tcctaaaggt aaaacagatg ctgaagtgat gcgcttctgc caaagcttca tgactgaatt
     1201 gcaaaaacac atcggaccat cacttgacgt acctgctggt gatatcggtg ttggtggacg
     1261 tgaaattggt tacctttacg gtcaatacaa acgtcttaac caatttgatg ctggtgtctt
     1321 gactggtaaa cctcttggat ttggtggtag cttgattcgt ccagaagcaa ctggttacgg
     1381 tttggtttac tatactgaag aaatgctcaa agctaacggt aacagctttg ctggtaagaa
     1441 agtcgttatt tcaggttctg gtaacgttgc tcaatatgct cttcaaaaag caactgaact
     1501 cggtgcaact gttatttctg tttctgactc aaatggttat gtcatcgatg aaaatggtat
     1561 cgacttcgat cttttggttg atgttaaaga aaaacgtcgt gctcgtttga ctgagtatgc
     1621 agctgaaaaa gcaactgcaa cctaccacga aggtactgta tggacttacg ctggaaacta
     1681 tgacattgct cttccatgtg ccactcaaaa cgaaatcaac ggtgaagcag ctaaacgttt
     1741 ggttgctcaa ggcgttatct gtgtatctga aggtgccaac atgccgagcg accttgatgc
     1801 catcaaagtt tacaaagaaa atggtatctt ctacggacct gcaaaagctg ccaacgctgg
     1861 tggtgtagcc gtttcagctc ttgaaatgag ccaaaacagt cttcgcctct catggactcg
     1921 tgaagaagtt gatggccgtc tcaaagacat catgacaaac atcttcaaca cagctaaaac
     1981 gacttcagaa acatacggtc ttgataaaga ctaccttgca ggagctaaca ttgctgcctt
     2041 tgaaaatgta gcaaatgcca tgattgcaca aggtattgtt taagatttat ttactcaatc
     2101 ctcaatcact acgattgggg atttttagct tgaattaaaa aattggaaaa tctaattaaa
     2161 taaaatgaaa tgaaataaaa actgaacaaa ttgattgcgg aattcaaacc aatttctaac
     2221 atacttctag aaattaattt gacttttcta atcgatttgt tcatatctta tttcaattta
     2281 ctatacttac ttaacccttt ttatactcaa tgaaaatcaa agagcaaact aggaagcgag
     2341 ccgcaggctg tacttgagta cggcaaggca aagctgacgt ggtttgaaga gattttcaaa
     2401 gagtattaaa caaaaagaaa aaccgctact cctaagaata gcgatttaat catgttttta
     2461 agctactact gtagttgctc tattatttaa gtgttatgaa taacttcaat atctttaaag
     2521 ctttttgtta gatttataat ttcaactata gccatctcta ctccttagtt tacagcaaaa
     2581 aattatgctt aattcttatt gtttttgtaa acaatcagcg aacccaatac tattccattc
     2641 aacaagccta aagaaatacc atattcaact ggaaaatcta aaaaaattgc aaacactatt
     2701 ccaatcatca cccctagtga ggctattgtt aaaattacat attcattttc tttcttcatt
     2761 ttctttacac ctcatttcct ttttgtatat aagctgtagt actctccacc aagagttatt
     2821 aagtacttat gatttcctga ctcaacaatc ttaccacctt tcattacaaa aataatatcc
     2881 gcatccttaa tcgttgacaa tctatgagct ataattattt gagtacaacc ctgactttgt
     2941 atatactttg ttattctttc ctcattaata gtgtctaatg cactagttgc ttcatctaaa
     3001 attacaatac taggattatt tattaatgca cgtgccagtg ctatctgttg cctttgccca
     3061 cctgaaatat ttgaccccat ctctgagatg atagtattaa atttcatcgg catagccatg
     3121 atttcatcat agatttgaac tgctttacaa acttcctcta tcttttgtga agtaacttcg
     3181 tgctttaaag ttatattatc aagaatactt cggttcaata aaaatgaatc ctgtggaact
     3241 actcctaaat tttgacttaa tattttttta tctatttgat taatatttat accataaaat
     3301 aaaacttttc ctgtatcaat cttatataat cctgatggta tttttgataa tagacttcct
     3361 gcaaaactag aatcctagtt catgattgat aataccaaca atcaaattca tccgtaatcc
     3421 gaagcgttta cgatgatttc gataggttgt tgaaaacatt ttaagcgttt ttactttggc
     3481 aaagatgttc tcaaccttgc ttctctcctt agatagcaca tggttacagg ctttatcttc
     3541 agctgttagc ggcttgagtt tgctggattt acgtggagtt tgtgcttga
//
LOCUS       DAVBBO010000093         3297 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ST1
            SAMEA2066453-rid20184263.denovo.093, whole genome shotgun sequence.
ACCESSION   DAVBBO010000093 DAVBBO010000000
VERSION     DAVBBO010000093.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2066453
            Sequence Read Archive: ERR351777
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 3297)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3297)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980402.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980402.1
            Genome Coverage       :: 176x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:17:33
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,141
            CDSs (total)                      :: 2,104
            Genes (coding)                    :: 1,953
            CDSs (with protein)               :: 1,953
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 16S)
            partial rRNAs                     :: 1 (23S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 151
            CDSs (without protein)            :: 151
            Pseudo Genes (ambiguous residues) :: 0 of 151
            Pseudo Genes (frameshifted)       :: 73 of 151
            Pseudo Genes (incomplete)         :: 76 of 151
            Pseudo Genes (internal stop)      :: 40 of 151
            Pseudo Genes (multiple problems)  :: 32 of 151
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3297
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2066453-rid20184263.denovo.093"
                     /strain="ST1"
                     /db_xref="taxon:1313"
     gene            complement(384..1859)
                     /locus_tag="VQU30_002084"
     CDS             complement(384..1859)
                     /locus_tag="VQU30_002084"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000661022.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminotransferase class I/II-fold pyridoxal
                     phosphate-dependent enzyme"
                     /protein_id="HET2448116.1"
                     /translation="MKELDQNQAPIYEALVKLRKKRIVPFDVPGHKRGRGNPELVELL
                     GEKCVGIDVNSMKPLDNLGHPISIIRDAEELAADAFGASHAFLMIGGTTSSVQTMILA
                     TCKAGDKIILPRNVHKSAINALVLCGAIPIYIEMSVDPKIGIALGLENDRVAQAIKDH
                     PDAKAILINNPTYYGICSDLKGLTEMAHEAGMMVLVDEAHGAHLHFTGKLPISAMDAG
                     ADMAAVSMHKSGGSLTQSSLLLIGEQMNPEYVRQIINLTQSTSASYLLMASLDISRRN
                     LALRGKESFEEVIELSEYARHEINAIGGYYAYSKELIDGVSVCDFDVTKLSVYTQGIG
                     LTGIEVYDLLRDEYDIQIEFGDIGNILAYISIGDRIQDIERLVGALADIKRLYSRDGK
                     DLIAGEYIQPELVLSPQEAFYSERKSLTLDDSVGQVCGEFVMCYPPGIPILAPGERIT
                     REIVDYIQFAKERGCSLQGTEDPEVNHINVIKRKTNYKKSQ"
     gene            2566..3297
                     /locus_tag="VQU30_002085"
                     /pseudo
     CDS             2566..3297
                     /locus_tag="VQU30_002085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001155321.1"
                     /note="internal stop; incomplete; missing C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
BASE COUNT         1041 a          704 c          612 g          940 t
ORIGIN      
        1 ataagaaaga cgctcatggc atcgctctta aacttctttc tgaccccaat cgtgaacaat
       61 ttcaacacga taatcggcaa gtagaactaa aaatactgac tagacatatt catcgtctca
      121 agaaaaaaca gtctgattgg aaagtacaat acactcgttg tcttgatatc atctttcctg
      181 agttggataa aatcgttgga aagcattcag aatataccta ccaactcttg acacgctacc
      241 ctaatcctca gaaaaggatt gaggcaggat ttgataagct gatagaaatt aagcgattga
      301 ccgcttctaa ttcaagggct ttttgccgtg ctctaaaatc atcgccaaat catcaaattg
      361 aaataagaaa tagtttagat aaactattga cttttcttat agtttgtctt tctcttaata
      421 acgttgatat gattgacctc tggatcttcc gtcccttgga gggagcaacc acgttccttg
      481 gcgaattgga tatagtcgac aatttctcgt gtaatgcgtt caccaggagc caagatagga
      541 atacctggag ggtaacacat aacaaattct ccacagacct gtccaacaga atcatccaaa
      601 gttaaacttt ttctttctga atagaaggct tcttgcggag acagcactaa ctcgggctga
      661 atatattctc ctgctatcaa atcttttcca tctcttgaat agagtctctt aatatcagcc
      721 agagcaccaa ccaagcgctc gatgtcttgg atgcggtcgc cgatggaaat ataggccaag
      781 atattgccga tatcaccaaa ctcgatctga atgtcgtatt cgtctcgcaa gaggtcataa
      841 acctcgatac ctgttaagcc aataccctga gtgtaaactg acaacttagt tacgtcaaaa
      901 tcgcaaaccg aaacaccgtc tattaactct tttgagtagg catagtagcc accgatagca
      961 ttgatttcat gacgagcgta ctcggatagc tcaatgactt cctcaaacga ctctttacca
     1021 cgaagggcca agttgcgacg tgaaatatcc aaactagcca tcaataagta agaggcagat
     1081 gtagactggg tcaggtttat aatctgacga acgtactcgg gattcatctg ctccccgatt
     1141 aaaagaagcg aactttgtgt caaactccca ccagacttat gcatggaaac tgctgccata
     1201 tcagctcctg catccatagc agaaattgga agtttaccag tgaaatgcaa atgcgctcca
     1261 tgggcttcat ctactaaaac catcatgcca gcttcatgag ccatttctgt caaccccttt
     1321 aggtctgaac agatgccgta gtaagtagga ttgttgatta ggatagcctt agcatctgga
     1381 tggtccttta tggcctgtgc tactcggtca ttttcaagac ctaaagcgat accaatctta
     1441 ggatctacac tcatctcgat atagatggga atggcaccac atagaaccaa cgcattgata
     1501 gcagatttat ggacatttcg tggcagaata atcttatctc ctgccttgca ggttgccaga
     1561 atcatagtct gcaccgatga agttgttcca ccaatcatta gaaaggcatg gctagctcca
     1621 aaagcatctg cagccagctc ctctgcatca cgaataatcg aaataggatg gcctaaatta
     1681 tccaagggtt tcatcgaatt gacatcaatg cctacacatt tttctcctaa gagttcgaca
     1741 agttctggat ttccccgtcc acgcttgtga cctggaacat caaagggaac aatccttttc
     1801 ttgcgtaact tcaccaaggc ctcataaatt ggggcttggt tttgatctaa ctctttcaaa
     1861 acatactcct ttcaatattt ttaggacctt atgaaaacta aggaactaaa ggttgactca
     1921 tgaaaaaaga gcaggttttc acctgctctg caatcttctg acgtgtttat tttggtttct
     1981 gttgagtatg tctgttcccg atgtttccta actctctagt agcaaatatt acgtacttta
     2041 ttgatcgttt cacaagatga cgtgtgcttt caccacacta aaaatttatg aattaggaca
     2101 agtgtcctaa catcaactta taaaagtagg cttttaaccc tatcaataat gtggcttttc
     2161 aaccacgctt cggcattcaa ccctgcctgt ccgtaggcat tttttactcg ggtttatatt
     2221 tgctagaaaa catcatctca ttttctaagc tttattacta tatcatgttt ttaagaactt
     2281 gtaaagtatt ttttgataaa aaacaaaaat ataatagatt gaaactagaa tagtacacct
     2341 ctgcttctaa aacattgtta gaaatagatt ttactgtcct gatcgatttg ttctgttctt
     2401 gtttcatttt actatatgtt cgtaaatgaa agttctataa tgaagttagc cacccagccc
     2461 tcctaaaaat tagatggttc aactagctga tagctcttgt aggcataaga aaacacctct
     2521 gtgttatact tgttgttcaa ccacaaacac aagaaaggca cagaaatgca agacaattat
     2581 actacaaaag gtaaacattt gacaatcgat agccgtcgct taatcgaaag atggaaaaaa
     2641 gaaggaaaat caaatagaga aattgcctct ctacttggaa aagctcctca aactatccac
     2701 actaaaatca agcgtaggac agtccgaaaa tgtcttggaa aagggcgctt caaagaggtt
     2761 tattctgccg actatgctca acagtcttat gaaaataatc gcaagcactc ggtcaagaga
     2821 tcaagcgtga ccaaggaact aaaggaaaag attctccact atcataacca aaaatttttg
     2881 cctgaaatga tggttatggc taaaggggtt aacgtgggaa tttcaaccat ttactattgg
     2941 attcatcatg gaaaattggg gtaaagcaag caggatctgc tttaccctag aaaaggaaaa
     3001 gtgcttaaga aacaggccag caccaacttt aaacctgctg gtcaatccat cgaacagcgg
     3061 cttgaagcta tcaattttcg cttggagaat gggcattatg agattgatac ggttctactt
     3121 acgagagcga aaaactactg cttgcttgtc ttgacggatc gaaaaagtag acatcagatc
     3181 atccgattga ttccaaataa aagtgctgag gtggtcaatc aggctctaaa actcatctta
     3241 aaacaacaca agattctttc catcacggca gataatggaa cggaattcaa tcgcttg
//
LOCUS       DAVBBO010000094         3262 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ST1
            SAMEA2066453-rid20184263.denovo.094, whole genome shotgun sequence.
ACCESSION   DAVBBO010000094 DAVBBO010000000
VERSION     DAVBBO010000094.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2066453
            Sequence Read Archive: ERR351777
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 3262)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3262)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980402.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980402.1
            Genome Coverage       :: 176x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:17:33
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,141
            CDSs (total)                      :: 2,104
            Genes (coding)                    :: 1,953
            CDSs (with protein)               :: 1,953
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 16S)
            partial rRNAs                     :: 1 (23S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 151
            CDSs (without protein)            :: 151
            Pseudo Genes (ambiguous residues) :: 0 of 151
            Pseudo Genes (frameshifted)       :: 73 of 151
            Pseudo Genes (incomplete)         :: 76 of 151
            Pseudo Genes (internal stop)      :: 40 of 151
            Pseudo Genes (multiple problems)  :: 32 of 151
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3262
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2066453-rid20184263.denovo.094"
                     /strain="ST1"
                     /db_xref="taxon:1313"
     gene            complement(216..827)
                     /gene="rpsD"
                     /locus_tag="VQU30_002086"
     CDS             complement(216..827)
                     /gene="rpsD"
                     /locus_tag="VQU30_002086"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407971.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S4"
                     /protein_id="HET2448117.1"
                     /translation="MSRYTGPSWKQARRLGLSLTGTGKELARRNYVPGQHGPNNRSKL
                     SEYGLQLAEKQKLRFTYGVGEKQFRNLFVQATKIKGGILGFNFMLLLERRLDNVVYRL
                     GLATTRRQARQFVNHGHILVDGKRVDIPSYRVTPGQVISVREKSLKVPAILEAVEATL
                     GRPAFVSFDAEKLEGSLTRLPERDEINPEINEALVVEFYNKML"
     gene            complement(1022..2074)
                     /locus_tag="VQU30_002087"
     CDS             complement(1022..2074)
                     /locus_tag="VQU30_002087"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000769768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HET2448118.1"
                     /translation="MKLKSYILVGYIISTLLTILVVFWAVQKMLIAKGEIYFLLGMTI
                     VASLVGAGISLFLLLPVFTSLGKLKEHAKRVAAKDFPSNLEVQGPVEFQQLGQTFNEM
                     SHDLQVSFDSLEESEREKGLMIAQLSHDIKTPITSIQATVEGILDGIIKESEQAHYLA
                     TIGRQTERLNKLVEELNFLTLNTARNQVETTSKDSIFLDKLLIECMSEFQFLIEQERR
                     DVHLQVIPESARIEGDYAKLSRILVNLVDNAFKYSAPGTKLEVVTKLEKGQLSISVTD
                     EGQGIAPEDLENIFKRLYRVETSRNMKTGGHGLGLAIARELAHQLGGEITVSSQYGLG
                     STFTLVLNLSGSENKA"
     gene            complement(2071..2769)
                     /locus_tag="VQU30_002088"
     CDS             complement(2071..2769)
                     /locus_tag="VQU30_002088"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000520636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HET2448119.1"
                     /translation="MGKTILLVDDEVEITDIHQRYLIQAGYQVLVAHDGLEALELFKK
                     KPIDLIITDVMMPRMDGYDLISEVQYLSPEQPFLFITAKTSEQDKIYGLSLGADDFIA
                     KPFSPRELVLRVHNILRRLHRGGETELISLGNLKMNHSSHEVQIGEEMLDLTVKSFEL
                     LWILASNPERVFSKTDLYEKIWKEDYVDDTNTLNVHIHALRQELAKYSSDQTPTIKTV
                     WGLGYKIEKPRGQT"
     gene            complement(2936..>3262)
                     /locus_tag="VQU30_002089"
     CDS             complement(2936..>3262)
                     /locus_tag="VQU30_002089"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000671383.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HET2448120.1"
                     /translation="VKETSDTANGSLSPSNSGSGVTPMNHNHATGTTDSMPADTMTSS
                     TNTMAGENMAASANKMSDTMMSEDKAMLPNTGETQTSMASIGFLGLALAGLLGGLGLK
                     NKKEEN"
BASE COUNT          912 a          735 c          626 g          989 t
ORIGIN      
        1 ttttttacga aaatctattg aatatgccat aaaaggatta taccacattg tgtactattt
       61 ttggttcatt ttactatatc actttggact atatcggtct agttatgtct aaacgattat
      121 agctggatac taagagaaat caaaaaagca ctaagggaga acgtcccaaa gtgcttaata
      181 tcaaggcctc aaagcctgtc ttattcaata aaatattaca acatcttgtt gtagaattca
      241 acgacaagtg cttcgttgat ttctgggttg atttcgtcgc gttctggcaa gcgagtcaat
      301 gaaccttcca atttttcagc gtcgaatgat acgaatgctg gacgtccaag agtagcttct
      361 actgcttcaa ggattgctgg aactttcaat gatttttcac gaactgagat cacttgacct
      421 ggagttacgc ggtatgatgg gatatcaacg cgtttcccgt caacaaggat gtgaccgtgg
      481 tttacgaatt gacgagcttg acgacgagta gtcgcgagac caagacggta aacaacgtta
      541 tccaaacgac gttccaaaag aagcataaag ttgaaaccta ggattccgcc tttgattttt
      601 gtagcttgta cgaacaagtt acggaattgt ttttcaccta caccgtaagt gaaacgaagt
      661 ttttgttttt cagccaattg caaaccgtat tctgacaatt tagaacggtt gtttggtccg
      721 tgttgtcctg gtacgtagtt acgacgtgcc aattctttac ctgtacctgt aagtgaaagg
      781 ccaaggcgac gagcttgttt ccaagatggt cctgtataac gtgacatatg aatgtcctcc
      841 tgatataaat aatatttcgg tggaaatagt cacttagaaa gccctgattc gtgcagatgc
      901 ccttcgccta aacagccaag gttacttgtc ataagacacc tgttgacgag cttcatgctt
      961 tcctgctgat atttcacaca aaatccattt taccatgaat agctggattt gtaaaggggt
     1021 tttaggcttt attttcacta ccagagagat tgagaacgag ggtaaaggta cttcctagac
     1081 cgtactggct gctgactgtg atttccccac ccaattgatg ggccaattca cgcgcaatcg
     1141 caagtcctaa tccatgacca cctgtcttca tgttacgcga agtttcgaca cgataaaggc
     1201 gtttgaaaat attttccaaa tcctctgggg caatgccctg cccttcatcg gtcacactga
     1261 ttgaaagctg gcccttctcc agcttagtca ccacttccag cttggttcct ggagcagaat
     1321 atttaaaagc gttatcgacc agattcacca agatacgaga aagcttagca taatctccct
     1381 caatccgggc agactctggg attacctgca agtggacatc tcttctctcc tgctcaatca
     1441 aaaactgaaa ttcactcatg cactcaatta agagcttgtc cagaaaaata ctgtctttac
     1501 tggtagtttc cacctgattt ctagctgtgt ttagggtcaa aaaattcaac tcctcaacca
     1561 gtttattgag cctctccgtc tggcgtccaa tggttgctag ataatgagct tgctccgact
     1621 ccttgataat cccatccaaa atcccttcta ccgtcgcttg gatcgaagtg ataggggtct
     1681 taatatcatg cgacaactgg gcaatcatca agcccttttc tcgttcgctt tcttccaagg
     1741 aatcaaagct tacctgcaaa tcatgggaca tctcattaaa agtttgccct aattgctgaa
     1801 attctacagg accttgaacc tccaaatttg aaggaaaatc cttggccgct acccgcttgg
     1861 catgctcctt gagtttgccc aacgacgtaa agactggcaa taggagaaag agactaatcc
     1921 cagcaccgac aaggctggca acgatggtca tcccaagcaa aaagtaaatc tcgcctttcg
     1981 caatcagcat tttttgaaca gcccaaaaaa caaccaaaat ggttaagagg gttgaaataa
     2041 tatatccaac caaaatataa ctttttagtt tcatgtttgt cctctcggtt tctctatctt
     2101 atatcccaac ccccaaactg tcttaatagt gggcgtttgg tcactactat attttgccag
     2161 ctcctgtcga agagcatgga tatgcacatt caaggtattg gtgtcatcca cgtagtcttc
     2221 tttccagatc ttttcataga ggtctgtctt ggagaaaact cgctctggat tgctagctaa
     2281 aatccacagc aattcaaatg atttaacagt taaatccagc atttcttctc ctatttgaac
     2341 ttcatgacta ctatgattca tttttagatt gccaagggaa atcagctctg tttcgccccc
     2401 acgatgaagg cggcgcaaaa tattgtggac acgcaaaacc agctcacgtg ggctaaaagg
     2461 cttagcaata aaatcatctg ctcccaagct caggccgtaa atcttgtcct gttcactggt
     2521 cttagcagta ataaatagga aaggctgctc tggtgataag tattgaacct cactgattaa
     2581 atcataacca tccatccgag gcatcataac atctgtgata atcaaatcaa tcggtttttt
     2641 cttgaacagc tctagcgctt ccagtccatc atgggctacc aagacctgat aacctgcctg
     2701 aattaagtat ctctgatgaa tatctgtgat ttctacctcg tcgtcaacga gtaaaattgt
     2761 ctttcccatc tgtctctcct ttgataaaaa cagtgctata ctgctttaag tataacacta
     2821 tttttattgt tttacgatga ttttaatctg ctattgaaag aaagtcctga ttgctgattg
     2881 agttgttaaa ctaatcttag tcagcccact atccatcatt tatttcctta gctgattagt
     2941 tttcttcttt tttgtttttc aaacctagac caccgagtaa acctgcaagc gcaagcccaa
     3001 ggaaaccaat acttgccatt gatgtttgag tctcaccagt atttggtagc atagctttat
     3061 cctctgacat catcgtatca gacatcttgt tagcagaagc agccatgttt tcacctgcca
     3121 tcgtgttggt agaacttgtc atggtgtcag caggcatgct atctgtagta cctgtagcat
     3181 gattgtgatt catcggagtc acgccagaac cagagttaga aggtgataat gaaccatttg
     3241 ctgtgtctga tgtttcttta ac
//
LOCUS       DAVBBO010000095         2624 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ST1
            SAMEA2066453-rid20184263.denovo.095, whole genome shotgun sequence.
ACCESSION   DAVBBO010000095 DAVBBO010000000
VERSION     DAVBBO010000095.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2066453
            Sequence Read Archive: ERR351777
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2624)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2624)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980402.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980402.1
            Genome Coverage       :: 176x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:17:33
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,141
            CDSs (total)                      :: 2,104
            Genes (coding)                    :: 1,953
            CDSs (with protein)               :: 1,953
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 16S)
            partial rRNAs                     :: 1 (23S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 151
            CDSs (without protein)            :: 151
            Pseudo Genes (ambiguous residues) :: 0 of 151
            Pseudo Genes (frameshifted)       :: 73 of 151
            Pseudo Genes (incomplete)         :: 76 of 151
            Pseudo Genes (internal stop)      :: 40 of 151
            Pseudo Genes (multiple problems)  :: 32 of 151
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2624
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2066453-rid20184263.denovo.095"
                     /strain="ST1"
                     /db_xref="taxon:1313"
     gene            206..520
                     /locus_tag="VQU30_002090"
     CDS             206..520
                     /locus_tag="VQU30_002090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001829577.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2448121.1"
                     /translation="MWVLGFILFLIFFYSNDSKKIKKLEKKIKRLERKEKGNAEMSRL
                     LQEMIGKEPIITGVYIGPDNWEVVDVDEEWVKLRRVDNTGKEKFKLQRIEDIQTVEFD
                     GE"
     gene            530..736
                     /locus_tag="VQU30_002091"
     CDS             530..736
                     /locus_tag="VQU30_002091"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001176227.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HET2448122.1"
                     /translation="MQLKNRLKELRARDGLNQTDLAKLAGVSRQTISLLERDEYTPSI
                     IIALKISQIFNETVESVFRLEEDE"
     gene            736..933
                     /locus_tag="VQU30_002092"
     CDS             736..933
                     /locus_tag="VQU30_002092"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001046145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2448123.1"
                     /translation="MNKYKVIYYVVVIALLVSVFLLIGMDLSWFNPYQSDQFVWVYFA
                     LIPVIEWIEKKSKNLASEKGE"
     gene            989..1669
                     /locus_tag="VQU30_002093"
     CDS             989..1669
                     /locus_tag="VQU30_002093"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001833114.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3169 family protein"
                     /protein_id="HET2448124.1"
                     /translation="MGMFVGMFKARVESHEIILDVKALMPWISAICLLIGFISMFLTF
                     NFLKKSRKFHSLYQEEMDDDLNETYYVQMYRNLEFGTIAFNITGVVIPLAIFISLSEV
                     IILHTNPQTFFLSFLLFVVFLVAQKSLFKTIAIVRQFDLEFFATPKDVLNYINSYDEG
                     ERQANLEQSFRILFQLHQYVLPALYIFLIILSFLTGEIQLLAFLLVGAIHVYINVMQL
                     PMVKRYFK"
     gene            1681..2322
                     /locus_tag="VQU30_002094"
     CDS             1681..2322
                     /locus_tag="VQU30_002094"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004258056.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HET2448125.1"
                     /translation="MKLLKNLGWFLLALLSFFFIYGFIQGLATASLALGASPYAVTLL
                     YVVLAGVYVYGIYKWYQKAPVYIEKSGFNRFIWLPALVWFLSLVVQFFLPDDPSVNQQ
                     IATDLTLSQPLFSFFAVVIFAPLTEEIVFRGMLARYLFPKQDNSKRTLIFLLVSSLLF
                     ALIHFPGDVQQFFVYFSLGFSLGLAYISRKGLVYSISLHALNNLVGFLMILML"
     gene            2340..2570
                     /locus_tag="VQU30_002095"
     CDS             2340..2570
                     /locus_tag="VQU30_002095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000832182.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2448126.1"
                     /translation="MKRVILLAVIQAVVLFFIIGALAYAFKGDFFYNYLAVVFAPIAG
                     VLRFGTAYITEIVLPRKAAEIAEKRKAGKNSK"
BASE COUNT          766 a          431 c          541 g          886 t
ORIGIN      
        1 atacctacgg caaggtgaag ctgacgtggt ttgaagagat tttagaagag tattaatgat
       61 agataaagtg gtcaggaacc tactcctgac ctttttcttt tgcaaaatga caaaaatcat
      121 aatttttttg acaactatac ttgtcaaaaa gaaaaagatg tgttacaatg taagcaagtt
      181 aagagaaaag aagaaaggag ctatgatgtg ggtactaggg tttatactat ttctgatttt
      241 cttttattct aatgattcta aaaaaatcaa gaaactagag aagaaaatca aaagacttga
      301 gcgaaaagag aaaggaaatg cagaaatgtc gagattatta caagaaatga ttggaaagga
      361 accaattata acgggagtgt atattgggcc agataactgg gaagttgtgg atgttgatga
      421 ggaatgggta aagctacgac gtgtagataa tacgggaaaa gaaaaattca agttgcaacg
      481 tattgaggat atccaaaccg ttgaatttga cggagagtag gtgtgtaaca tgcaactaaa
      541 aaatcgtcta aaagagcttc gagctcgcga tggtctcaat caaaccgacc tagccaaact
      601 ggcaggggtt tccagacaga ccattagcct actagaacgg gatgagtaca ccccatccat
      661 tatcattgcc ctgaaaatat ctcaaatttt caacgaaaca gtcgaatcgg tatttcgttt
      721 ggaggaggac gagtgatgaa caagtataaa gtgatttatt atgtagtggt catagcttta
      781 ttagtcagcg tatttctact gattgggatg gacctaagct ggtttaatcc ctatcaaagc
      841 gaccaatttg tttgggtcta ctttgctctc atcccagtaa ttgaatggat tgaaaagaaa
      901 tccaaaaatc tagcaagtga aaaaggagaa tgaatatgaa aaagaaacgt agattgttat
      961 ttttgatgtc tattgtcttg gggggttctt gggcatgttt gtagggatgt ttaaggcacg
     1021 tgtcgaatcc cacgaaatta ttttagatgt aaaagccttg atgccatgga tatcagctat
     1081 ttgtttactg ataggtttca ttagtatgtt tttgactttc aatttcttaa agaaaagcag
     1141 aaaatttcat tccttgtatc aagaggaaat ggatgacgat ctgaatgaaa cctattatgt
     1201 gcaaatgtat cggaatcttg agtttggaac cattgctttt aatattacag gtgtagtgat
     1261 tccattggct atttttattt cattaagtga ggtgattata ttgcatacaa accctcaaac
     1321 atttttcctt tctttcttac tctttgtggt attcttagtc gctcaaaaat ctctttttaa
     1381 aaccattgcg attgttcgtc agtttgattt ggaatttttc gctacaccaa aggatgtctt
     1441 gaactatata aattcttatg atgaagggga gcgtcaggct aatttggaac agagttttcg
     1501 aattttattc caattacacc aatatgtctt accagcctta tatatttttc ttattatcct
     1561 ttctttcttg acaggagaga ttcagttact agctttcttg cttgtaggag ccatccatgt
     1621 ttatatcaat gtgatgcagt tacctatggt aaaacgttat ttcaaataaa ggagttatct
     1681 atgaaattac ttaaaaacct tggctggttt cttctagccc ttctatcctt tttctttatc
     1741 tatggcttta ttcaggggct cgcgactgcg tcgcttgctt taggcgcttc accctatgct
     1801 gttactctac tctatgtggt cttggctgga gtatatgtgt acggcattta caaatggtat
     1861 cagaaagctc ctgtttatat tgagaagagc ggctttaacc gatttatttg gcttcctgcc
     1921 ttggtttggt tcttatctct ggtcgttcaa ttcttcttgc cagatgatcc ttcagtaaat
     1981 cagcaaatag cgacagactt gaccttgtct caaccacttt tctcattctt tgctgtggtt
     2041 atttttgctc ctttgacgga agagattgtt tttagaggga tgttagcacg ctatctcttt
     2101 cctaagcagg acaatagtaa acgaaccctg atttttcttc tggtatctag tcttctattt
     2161 gccttgattc attttccagg tgatgtgcaa caattttttg tctattttag ccttggtttt
     2221 agtttgggtt tggcttacat tagcagaaaa ggtctggtct acagtatttc tcttcacgct
     2281 ttgaataatt tagtcggctt tttgatgatt ctcatgctat aatagagtca ggaggtcaca
     2341 tgaaacgagt aattttatta gcagtgattc aggcagtcgt tctatttttc atcattggag
     2401 cgctagctta tgccttcaaa ggcgatttct tctataacta tctagcagtt gtctttgctc
     2461 ctattgcagg tgtactgcgt tttgggacgg cttacataac ggaaattgtc ttgcctcgaa
     2521 aggcagccga aatcgctgaa aagcgtaaag caggcaaaaa ttcaaaataa aagagtccgg
     2581 tgaagttcat cggatttttg tattatactc aatgaaaatc aaag
//
LOCUS       DAVBBO010000096         2398 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ST1
            SAMEA2066453-rid20184263.denovo.096, whole genome shotgun sequence.
ACCESSION   DAVBBO010000096 DAVBBO010000000
VERSION     DAVBBO010000096.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2066453
            Sequence Read Archive: ERR351777
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2398)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2398)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980402.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980402.1
            Genome Coverage       :: 176x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:17:33
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,141
            CDSs (total)                      :: 2,104
            Genes (coding)                    :: 1,953
            CDSs (with protein)               :: 1,953
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 16S)
            partial rRNAs                     :: 1 (23S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 151
            CDSs (without protein)            :: 151
            Pseudo Genes (ambiguous residues) :: 0 of 151
            Pseudo Genes (frameshifted)       :: 73 of 151
            Pseudo Genes (incomplete)         :: 76 of 151
            Pseudo Genes (internal stop)      :: 40 of 151
            Pseudo Genes (multiple problems)  :: 32 of 151
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2398
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2066453-rid20184263.denovo.096"
                     /strain="ST1"
                     /db_xref="taxon:1313"
     gene            complement(26..428)
                     /locus_tag="VQU30_002096"
                     /pseudo
     CDS             complement(26..428)
                     /locus_tag="VQU30_002096"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase family protein"
     gene            complement(373..555)
                     /locus_tag="VQU30_002097"
     CDS             complement(373..555)
                     /locus_tag="VQU30_002097"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812165.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HET2448127.1"
                     /translation="MDLKFEGVDLEYKKAKNNLPESFWETYSAFANTNGGKIILGIDE
                     KNIDTYQRVNRLPAKL"
     gene            912..>2398
                     /gene="pcpA"
                     /locus_tag="VQU30_002098"
     CDS             912..>2398
                     /gene="pcpA"
                     /locus_tag="VQU30_002098"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000753868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choline-binding protein PcpA"
                     /protein_id="HET2448128.1"
                     /translation="MKKTTILSLTTAAVILAAYVPNEPILADTPSSEVIKETKVGSII
                     QQNNIKYKVLTVEGNIGTVQVGNGVTPVEFEAGQDGKPFTIPTKITVGDKVFTVTEVA
                     SQAFSYYPDETGRIVYYPSSITIPSSIKKIQKKGFHGSKAKTIIFDKGSQLEKIEDGA
                     FDFSELEEIELPASLEYIGTSAFSFSQKLKKLTFSSSSKLELISHEAFANLSNLEKLT
                     LPKSVKTLGSNLFRLTTSLKHVDVEEGNESFASVDGVLFSKDKTQLIYYPSQKNDESY
                     KTPKETKELASYSFNKNSYLKKLELNEGLEKIGTFAFADAIKLEEISLPNSLETIERL
                     AFYGNLELKELILPDNVKNFGKHVMNGLPKLKSLTIGNNINSLPSFFLSGVLDSLKEI
                     HIKNKSTEFSVKKDTFAIPETVKFYVTSEHIKDVLKSNLSTSNDIIVEKVDNIKQETD
                     VAKPKKNSNQGVVGWVKDKGLWYYLNESGSKATGWVKDKGLWYYL"
BASE COUNT          837 a          359 c          397 g          805 t
ORIGIN      
        1 tgagccttca tagcgtggca tttcttttta cttccgtcac atcaatcatt accgtgtcct
       61 cagaactgag aggagttctt gaaatcgtaa caccaccttt gaacaagagt tacttcaacc
      121 cattagctcc gacggattaa gttgctttcg tgaataccaa aatcagccgc aatttcttca
      181 taagtgcggt attctcgcac atattgaaga gtggccataa gaaggtcttc taggcttaat
      241 ttaggttttc gtccaccttt tgtgtgttta agttgataag ctgtttttaa cacagctaac
      301 atctcttcaa aagtggtgcg ctgaacacca acaagacgct taaatcgtgc atcggttagt
      361 tgtttacttg cttcataatt tcgcagggag tctattgact ctttggtagg tgtcaatgtt
      421 tttttcatct atcccgagaa ttattttccc gccatttgta tttgcaaatg ctgagtaggt
      481 ttcccagaaa gactctggaa gattgttttt agcttttttg tattctaaat caaccccttc
      541 aaattttaag tccatatttt tcctttacat ctgttttttg tggttctggt atttgttcaa
      601 gttgagtgat aatatagcga attgaatttc gagagttttt actcagttaa tttctttttt
      661 aacccacttt aatttctttt ttaacccact ttaatttctt ttttaacacg ggttaaaaaa
      721 gaaattaaag tgggttaatt tttcttgact taaaatttaa aaatgatata ctgtgtttat
      781 ggagagatga caatttataa aatgtactac tctattctac tagataatga ttgaataaaa
      841 ctttttataa caacggctag caaagttata attttatatc tattagaaaa taaatatgta
      901 aggaaattta aatgaaaaaa actacaatat tatcattaac tacagctgcg gttattttag
      961 cagcatatgt ccctaatgaa ccaatcctag cagatactcc tagttcggaa gtaatcaaag
     1021 agactaaagt tggaagtatt attcaacaaa ataatatcaa atataaggtt ctaactgtag
     1081 aaggtaacat aggaactgtt caagtgggta atggagttac tcctgtagag tttgaagctg
     1141 gtcaagatgg aaaaccattc acgattccta caaaaatcac agtaggtgat aaagtattta
     1201 ccgttactga agtagctagt caagctttta gttattatcc agatgaaaca ggtagaattg
     1261 tctactatcc tagctctatt actatcccat caagcataaa aaaaatacaa aaaaaaggct
     1321 tccatggaag taaagctaaa actattattt ttgacaaagg cagtcagctg gagaaaattg
     1381 aagatggagc ttttgatttt tctgaattag aagagattga attgcctgca tctctagaat
     1441 atattggaac aagtgcattt tcttttagtc aaaaattgaa aaagctaacc ttttcctcaa
     1501 gttcaaaatt agaattaata tcacatgagg cttttgctaa tttatcaaat ttagagaaac
     1561 taacattacc aaaatcggtt aaaacattag gaagtaatct atttagactc actactagct
     1621 taaaacatgt tgatgttgaa gaaggaaatg aatcgtttgc ctcagttgat ggtgttttgt
     1681 tttcaaaaga taaaacccaa ttaatttatt atccaagtca aaaaaatgac gaaagttata
     1741 aaacgcctaa ggagacaaaa gaacttgcat catattcgtt taataaaaat tcttacttga
     1801 aaaaactcga attgaatgaa ggtttagaaa aaatcggtac ttttgcattt gcagatgcga
     1861 ttaaacttga agaaattagc ttaccaaata gtttagaaac tattgaacgt ttagcctttt
     1921 acggtaattt agaattaaaa gaacttatat taccagataa tgttaaaaat tttggtaaac
     1981 acgttatgaa cggtttacca aaattaaaaa gtttaacaat tggtaataat atcaactcat
     2041 tgccgtcctt cttcctaagt ggcgtcttag attcattaaa ggaaattcat attaagaata
     2101 aaagtacaga gttttctgtg aaaaaagata catttgcaat tcctgaaact gttaagttct
     2161 atgtaacatc agaacatata aaagatgttc ttaaatcaaa tttatctact agtaatgata
     2221 tcattgttga aaaagtagat aatataaaac aagaaactga tgtagctaaa cctaaaaaga
     2281 attctaatca gggagtagtt ggttgggtta aagacaaagg tttatggtat tacttaaatg
     2341 aatcaggttc aaaggctact ggttgggtta aagacaaagg cttatggtat tacttaaa
//
LOCUS       DAVBBO010000097         2103 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ST1
            SAMEA2066453-rid20184263.denovo.097, whole genome shotgun sequence.
ACCESSION   DAVBBO010000097 DAVBBO010000000
VERSION     DAVBBO010000097.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2066453
            Sequence Read Archive: ERR351777
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2103)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2103)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980402.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980402.1
            Genome Coverage       :: 176x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:17:33
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,141
            CDSs (total)                      :: 2,104
            Genes (coding)                    :: 1,953
            CDSs (with protein)               :: 1,953
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 16S)
            partial rRNAs                     :: 1 (23S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 151
            CDSs (without protein)            :: 151
            Pseudo Genes (ambiguous residues) :: 0 of 151
            Pseudo Genes (frameshifted)       :: 73 of 151
            Pseudo Genes (incomplete)         :: 76 of 151
            Pseudo Genes (internal stop)      :: 40 of 151
            Pseudo Genes (multiple problems)  :: 32 of 151
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2103
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2066453-rid20184263.denovo.097"
                     /strain="ST1"
                     /db_xref="taxon:1313"
     gene            <1..141
                     /locus_tag="VQU30_002099"
     CDS             <1..141
                     /locus_tag="VQU30_002099"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000242196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HET2448129.1"
                     /translation="INNSSSSQTNILAQLMDFFTGNGHLEDLSKISEPEKLYAYIAEA
                     TA"
     gene            179..484
                     /locus_tag="VQU30_002100"
     CDS             179..484
                     /locus_tag="VQU30_002100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000590575.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HET2448130.1"
                     /translation="MIKILAACGAGVNSSHQIKSALEEELSNRGYDVHCDAVMVKDVN
                     EDLMKGYDIFTPIAATDLGFEPGIPVIEAGPILFRIPAMSAPVFDNIEAAIKEHGLS"
     gene            532..2007
                     /locus_tag="VQU30_002101"
     CDS             532..2007
                     /locus_tag="VQU30_002101"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000338710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS galactitol transporter subunit IIC"
                     /protein_id="HET2448131.1"
                     /translation="MDAIFDLIGKVFNPILEMGGPVIMLIILTVLALLFGVKFSKALE
                     GGIKLAIALTGIGAIIGMLNGAFSASLAKFVENTGIQLSITDVGWAPLATITWGSAWT
                     LYFLLIMLIVNIVMLAMKKTDTLDVDIFDIWHLSITGLLIKWYADNNGVSQGVSLFIA
                     TAAIVLVGVLKIINSDLMKPTFDDLLNAPSSSPMTSTHMNYMMNPVIMVLDKIFEKFF
                     PGLDKYDFDAAKLNKKIGFWGSKFFIGFILGIVIGIMGTPHPIAGVADADKWRLVIKG
                     WLSLGLTAGVSLELFSLIGSWFIAAVEPLSQGITNVATKRLQGRKFNIGLDWPFIAGR
                     AEIWACANVLAPIMLIEAVLLSKVGNGILPLAGIIAMGVTPALLVVTRGKLLRMIIFG
                     TLLLPLFLLSGTLIAPFATELAKGVGAFPEGVSQTQLITHSTLEGPIEKLLGWTIGNT
                     TTGDIKAILGAVVFLVFYIGIFAWYRKQMIKRNEEYAAKAK"
BASE COUNT          619 a          421 c          415 g          648 t
ORIGIN      
        1 attaacaatt caagttcaag tcaaacaaat attctggctc agttgatgga ctttttcaca
       61 ggaaatggac atcttgaaga cctatcaaaa atttccgaac cagaaaaact ttatgcttac
      121 attgctgaag caaccgctta atcttgtcta ttaaaaaata aaatcggagg aaatccaaat
      181 gattaaaatt cttgctgcct gcggtgcagg tgttaactca agtcaccaaa ttaaaagtgc
      241 tctagaagaa gaactttcaa accgtggtta tgatgttcac tgtgatgcag tcatggtgaa
      301 agatgtaaac gaagacctta tgaaaggtta cgatatcttt acaccaatcg ctgcaacaga
      361 ccttggtttt gaaccaggta tcccagttat cgaagctggg ccaatcttat tccgtatccc
      421 agcaatgagc gctccagtat ttgacaatat tgaagcagct attaaagaac acggattaag
      481 ctaattctaa tttgttaaca ttcatataac ataaaaaagg gaggaactgt tatggatgca
      541 atctttgacc taatcggaaa ggttttcaat cccattttag aaatgggtgg acctgtcatc
      601 atgttaatca ttttgacagt attggcttta ctttttggag tgaaattctc caaagcgctt
      661 gaaggtggta tcaaacttgc catcgctctt acaggtatcg gtgctatcat cggtatgcta
      721 aatggtgctt tctcagcatc acttgcaaaa ttcgttgaaa acactggtat ccaattgagt
      781 attaccgacg ttggttgggc accactcgca acaatcactt ggggttctgc ttggacacta
      841 tacttcttgc tcatcatgtt gattgtcaac atagtgatgc tagctatgaa gaaaacagat
      901 acacttgacg ttgatatctt tgatatctgg cacttgtcta tcacaggtct cttgattaaa
      961 tggtatgctg ataacaatgg tgtgagtcaa ggggtttcac tctttattgc tacagcagct
     1021 atcgtccttg tcggtgtgtt gaaaattatc aactctgact tgatgaaacc tacatttgat
     1081 gaccttctta acgccccaag ttcatcacca atgacatcaa ctcacatgaa ctacatgatg
     1141 aacccagtta tcatggtttt ggataagatt tttgaaaaat tcttcccagg ccttgataaa
     1201 tatgactttg atgctgctaa attgaacaag aaaatcggtt tctggggatc taaattcttc
     1261 atcggtttca tccttggtat cgttatcggt attatgggaa ctccacatcc aattgcaggt
     1321 gttgcagatg cagataaatg gcgtcttgtt atcaaaggat ggttgtctct tggtttgact
     1381 gccggtgtat ctttggaact cttctcactt atcggttcat ggttcatcgc agccgtagaa
     1441 ccactatcac aaggtattac aaacgttgct actaaacgtc ttcaaggacg taaattcaat
     1501 atcggtcttg actggccatt catcgctggt cgtgctgaaa tctgggcttg tgccaacgta
     1561 cttgcaccaa tcatgttgat tgaagcagtg cttctttcaa aagttggaaa tggtatcttg
     1621 ccacttgcag gtatcatcgc tatgggtgtt actccagctc tcttggttgt aactcgtggt
     1681 aaattgctcc gtatgattat cttcggaaca ctcttgttgc cactcttcct tctttcaggt
     1741 acacttattg caccatttgc aacagaactt gctaaaggtg taggtgcctt cccagaaggt
     1801 gtgagccaaa ctcaattgat tactcactct actcttgaag gaccaatcga aaaacttctt
     1861 ggttggacaa ttggtaacac tacaactggt gatatcaaag caatccttgg tgcagtagtc
     1921 ttccttgtat tctatatcgg tatctttgct tggtacagaa aacaaatgat caaacgtaac
     1981 gaagagtacg cagcaaaagc aaaataatgc gctcctataa aatataaact caatgaaaat
     2041 caaagagcaa actaggaaac tagccacagg ttgctcaaaa cacagttttg aggttgtaga
     2101 taa
//
LOCUS       DAVBBO010000098         1651 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ST1
            SAMEA2066453-rid20184263.denovo.098, whole genome shotgun sequence.
ACCESSION   DAVBBO010000098 DAVBBO010000000
VERSION     DAVBBO010000098.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2066453
            Sequence Read Archive: ERR351777
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1651)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1651)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980402.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980402.1
            Genome Coverage       :: 176x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:17:33
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,141
            CDSs (total)                      :: 2,104
            Genes (coding)                    :: 1,953
            CDSs (with protein)               :: 1,953
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 16S)
            partial rRNAs                     :: 1 (23S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 151
            CDSs (without protein)            :: 151
            Pseudo Genes (ambiguous residues) :: 0 of 151
            Pseudo Genes (frameshifted)       :: 73 of 151
            Pseudo Genes (incomplete)         :: 76 of 151
            Pseudo Genes (internal stop)      :: 40 of 151
            Pseudo Genes (multiple problems)  :: 32 of 151
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1651
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2066453-rid20184263.denovo.098"
                     /strain="ST1"
                     /db_xref="taxon:1313"
     gene            108..407
                     /locus_tag="VQU30_002102"
     CDS             108..407
                     /locus_tag="VQU30_002102"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000378912.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lantibiotic biosynthesis protein"
                     /protein_id="HET2448132.1"
                     /translation="MDSYAINFWESKGVGIDKKILEFIQKNITVIKNKNFLNKDFDIY
                     VKKIHNLFFVISTLVSKEQYMGIVSSQIHMFANRMGISPTIEVTMLDFFLREDSD"
     gene            409..1179
                     /locus_tag="VQU30_002103"
     CDS             409..1179
                     /locus_tag="VQU30_002103"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000417117.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SagB/ThcOx family dehydrogenase"
                     /protein_id="HET2448133.1"
                     /translation="MEKYFFDISIFEKIKKVLSYQSKYWEISKPRDKYSFKSQNRISG
                     SNSIKFKDFELDYELESLGKILLKRRSFLLNEFDKNASFDKLIYLLKTVFSPTNCKFV
                     FGEEVPLFSYPTSGALNSITPFVYIDNMDEVKNGIYEVKYDGLEFKKSMNIIDLETFT
                     PITSKNSDVQNNSFKKVNMIIMLCSNYENIFNKYGLLAYRLLHLEAGHIAQNIQLVST
                     ALGIKSLPMGGWFDDKIETFINEISDKKNIYLYAIAVG"
     gene            1199..1363
                     /locus_tag="VQU30_002104"
     CDS             1199..1363
                     /locus_tag="VQU30_002104"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001818718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2448134.1"
                     /translation="MNAEDKFRELENENKLLKLHNKELENEIQNGWKFWIWVTVPILG
                     LIYAIIQKIF"
BASE COUNT          608 a          181 c          269 g          593 t
ORIGIN      
        1 ataactatta ttacgaaaaa aaattcttgt gtaaaattct attgactttc tatattattt
       61 ttgtatttca taacgaatgt aatttaacaa gtgaagaaat tttaaagatg gattcctatg
      121 ctattaattt ctgggagagt aaaggggtcg gtattgacaa aaaaatcttg gaatttattc
      181 aaaaaaatat tacagttatt aaaaataaaa attttttgaa taaagatttt gatatttatg
      241 ttaaaaagat tcataattta ttctttgtca tttctacttt agtttcaaaa gagcaataca
      301 tggggatagt ttcttcccaa atacatatgt tcgcaaatag gatgggaatt tctcccacca
      361 ttgaagttac catgctagat ttttttctga gggaggattc tgattaatat ggaaaaatat
      421 ttttttgata tttctatttt tgaaaaaata aaaaaagtat tatcatacca atctaaatat
      481 tgggaaatat cgaagcctag ggataagtac agtttcaaaa gtcaaaatag aatatctggc
      541 tctaatagca ttaaatttaa agattttgag ttagattatg aactggagtc acttggtaaa
      601 atacttttaa aaaggagatc gtttttacta aatgaatttg ataagaatgc gagttttgac
      661 aaactgattt acttgttgaa aactgtattc tctcctacaa attgcaagtt tgtatttgga
      721 gaagaggttc ctttatttag ctatcctaca tcaggtgcgt taaattcaat tactcctttt
      781 gtttatattg ataatatgga tgaagtaaag aatggtatat atgaagtaaa gtatgacgga
      841 cttgaattta aaaaaagtat gaatattata gacttagaaa catttacccc aataacaagt
      901 aaaaacagtg acgtacaaaa taattcattt aaaaaggtaa atatgataat tatgttatgt
      961 tcgaattatg aaaatatttt caataaatat ggattattag cttatcgact tttgcattta
     1021 gaggctggtc atattgcaca aaatatccag cttgtttcta ctgcgctagg aataaaaagt
     1081 ttaccgatgg gaggttggtt tgatgataaa atagaaactt ttattaatga aattagtgat
     1141 aaaaaaaata tttatctcta tgcaattgca gttggataaa tttaaggagg aagtgtagat
     1201 gaacgcagag gataaatttc gcgaactaga aaatgaaaat aaacttctaa aacttcataa
     1261 caaggagctt gagaatgaaa ttcaaaatgg atggaaattt tggatatggg taactgtccc
     1321 tattttaggt ttgatatatg ctattattca aaaaattttt taattatgct agtttgtcag
     1381 gttgagtagt ttttgttcaa aatttaataa acttttttca atgaagatta tctaaagatt
     1441 gcttctcaga tgagaatggc ttctctatct tatataaatt atcttcatag agtgtcctgt
     1501 tattcatgtt atcacagaat agatagtttt tttggctcta taatatttgt agtgggtaaa
     1561 tcccctatag atattatgga gcctattttt gtgtagaaaa aaagtcccat atcatctata
     1621 atgaaaagca accaaactat cattagaaag a
//
LOCUS       DAVBBO010000099         1586 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ST1
            SAMEA2066453-rid20184263.denovo.099, whole genome shotgun sequence.
ACCESSION   DAVBBO010000099 DAVBBO010000000
VERSION     DAVBBO010000099.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2066453
            Sequence Read Archive: ERR351777
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1586)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1586)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980402.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980402.1
            Genome Coverage       :: 176x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:17:33
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,141
            CDSs (total)                      :: 2,104
            Genes (coding)                    :: 1,953
            CDSs (with protein)               :: 1,953
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 16S)
            partial rRNAs                     :: 1 (23S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 151
            CDSs (without protein)            :: 151
            Pseudo Genes (ambiguous residues) :: 0 of 151
            Pseudo Genes (frameshifted)       :: 73 of 151
            Pseudo Genes (incomplete)         :: 76 of 151
            Pseudo Genes (internal stop)      :: 40 of 151
            Pseudo Genes (multiple problems)  :: 32 of 151
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1586
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2066453-rid20184263.denovo.099"
                     /strain="ST1"
                     /db_xref="taxon:1313"
     gene            84..491
                     /locus_tag="VQU30_002105"
     CDS             84..491
                     /locus_tag="VQU30_002105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001849729.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HET2448135.1"
                     /translation="MARYGVYAVIPNPEQKQIVLVQEPNGAWFLPCGEIEAGENHQEA
                     LKRELIEELGFTAEIGTYYGQADEYFYSRHRDTYYYNPAYLYEATSFKEVQKPLENFN
                     HIAWFPIDEAIQNLKRGSHKWAIESWKKQHKIG"
     gene            656..955
                     /locus_tag="VQU30_002106"
     CDS             656..955
                     /locus_tag="VQU30_002106"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000767202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1827 family protein"
                     /protein_id="HET2448136.1"
                     /translation="MKLINTTNSHSQLVKSQLESTDATLVEVYSAGNTDVIFTQAPLH
                     YEILISNKHRAIREPEIETIQEFFLKRKIDKTSVNEANIKTLYSEKLIGISIPIK"
     gene            1216..1539
                     /gene="tnpB"
                     /locus_tag="VQU30_002107"
     CDS             1216..1539
                     /gene="tnpB"
                     /locus_tag="VQU30_002107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001846105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS66 family insertion sequence element accessory
                     protein TnpB"
                     /protein_id="HET2448137.1"
                     /translation="MMIVLSDLGQVHLVCGKTDMRQGIDSLAYVVKTHFELDPFSGQV
                     FLFCGGRKDRFKALYWDGQGFWLLYKRFENGRLTWPSTEKDVKALTSEQVDWLMKGFS
                     ITPQI"
BASE COUNT          544 a          314 c          282 g          446 t
ORIGIN      
        1 actataataa taacgatact agataatgag gaaaatgcaa tggcaaaccc aactttcgga
       61 gaaaaaaagc gaatacagac tatattgctc gctatggcgt atatgcagtt atccctaatc
      121 ctgaacaaaa acaaattgtt cttgttcaag aaccaaatgg tgcttggttc ctaccatgtg
      181 gagaaattga agcaggtgaa aatcatcagg aagccctaaa gcgtgagttg attgaagagc
      241 ttggtttcac agcagaaatt ggtacctatt acggacaagc tgacgaatat ttctattctc
      301 gtcatcgtga tacctactac tacaatcctg cctacctcta tgaagcaact tctttcaaag
      361 aagtacaaaa gccactagaa aactttaatc atattgcctg gttccctatt gacgaggcta
      421 tccaaaacct taaacgtggt agccataaat gggccattga atcttggaaa aaacagcata
      481 agattggcta atactcttcg aaaataaaat tcaaaccacg tcagcgtcgc cttaccgtac
      541 tcaagtatag cctgcggcta gcttcctagt ttgctctttg attttcattg agtataaatc
      601 aagcgacttt attcaaaaag tgctataata gaattagaaa atcggaggaa atattatgaa
      661 gcttatcaat acgacaaact cacactcgca acttgtaaaa agtcaactag aaagtaccga
      721 tgcaaccctt gttgaggttt attctgcagg gaatacagat gttattttta cccaagctcc
      781 gcttcactat gaaatcctca tctcaaacaa acaccgtgct attcgtgagc ctgaaatcga
      841 aaccattcaa gaatttttct tgaaacgtaa aattgataag acctctgtta atgaagccaa
      901 tatcaagaca ctctactcag agaaattaat tggaatttca atcccaatca agtaagaaaa
      961 ttgagtaaaa actcgatttg agagaaagtc caataagtct ttccataaca aaacgcatag
     1021 taacaagagt ttctacaccc actattatac gtttttatca ttttgaaatc tgctgctaat
     1081 caatgaagaa gcaaagatca aactaggcag ctagttacaa gttacgtaag cgcgtcataa
     1141 caaggtatct atcctaattc cccaacttcc agtatactag ataaaaaata attatcagag
     1201 gaaaggtatt gtactatgat gattgtacta agtgatttag gtcaagttca ccttgtttgt
     1261 ggcaagacag atatgaggca gggaatagac tcattagcct atgtagttaa aacccacttt
     1321 gaattggatc ctttctccgg tcaagtcttt ctcttttgtg gtggacgtaa agaccgcttt
     1381 aaagcccttt actgggatgg tcaaggattt tggctactat ataaacgctt tgagaacggc
     1441 agactgactt ggcccagtac agaaaaggat gtcaaagctc tcacatctga acaagtagac
     1501 tggcttatga agggcttttc tatcactccc caaatatagt ggatttaaac tagaatagta
     1561 cacctctact tctaaaacat tgttag
//
LOCUS       DAVBBO010000100         1419 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ST1
            SAMEA2066453-rid20184263.denovo.100, whole genome shotgun sequence.
ACCESSION   DAVBBO010000100 DAVBBO010000000
VERSION     DAVBBO010000100.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2066453
            Sequence Read Archive: ERR351777
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1419)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1419)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980402.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980402.1
            Genome Coverage       :: 176x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:17:33
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,141
            CDSs (total)                      :: 2,104
            Genes (coding)                    :: 1,953
            CDSs (with protein)               :: 1,953
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 16S)
            partial rRNAs                     :: 1 (23S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 151
            CDSs (without protein)            :: 151
            Pseudo Genes (ambiguous residues) :: 0 of 151
            Pseudo Genes (frameshifted)       :: 73 of 151
            Pseudo Genes (incomplete)         :: 76 of 151
            Pseudo Genes (internal stop)      :: 40 of 151
            Pseudo Genes (multiple problems)  :: 32 of 151
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1419
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2066453-rid20184263.denovo.100"
                     /strain="ST1"
                     /db_xref="taxon:1313"
     gene            complement(82..634)
                     /locus_tag="VQU30_002108"
                     /pseudo
     CDS             complement(82..634)
                     /locus_tag="VQU30_002108"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007897432.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing N-terminus and C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(710..937)
                     /locus_tag="VQU30_002109"
     CDS             complement(710..937)
                     /locus_tag="VQU30_002109"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001827253.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HET2448138.1"
                     /translation="MRERLLTQPLLHADETSYRVLESHSHLTYYWTFLSGKVENQAIT
                     LYHHDQSRSGSVVQEFLGDYSGYVHCDMLRQ"
     gene            965..1150
                     /locus_tag="VQU30_002110"
                     /pseudo
     CDS             965..1150
                     /locus_tag="VQU30_002110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611577.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            1245..1419
                     /locus_tag="VQU30_002111"
                     /pseudo
     CDS             1245..1419
                     /locus_tag="VQU30_002111"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000433508.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus and C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
BASE COUNT          439 a          304 c          259 g          417 t
ORIGIN      
        1 aacaaatcga ttaggaaagg aaaattgatt tatagaaatg ttttagcagt cgatgcgtac
       61 tgttatagat tcaacgcact ataattgatg acgtttagct gtttccaaca agctcataat
      121 aatagctctt gctttagctc cttcaaaact ttgagaaaat aaccaccctc gcttttttaa
      181 actgagctca ggctaaaaga gtccactgga ctcttttact ccgtcccata accaatgatt
      241 taatggcgcg ttcagctaga ttattggaaa ggaccagatg tccgtctttc aaaatagtct
      301 taaaggtttc ttcatacttg aggctgtatt caattgccct tcctagtttt gaacctgcta
      361 aaactgactg acggcggcac caagcaaaga agtcttccat taggggctgg agatgttctt
      421 gacgtttctg tagtcgttca tcagctggca aagcctccca gtctctttcc aaggaaaata
      481 actgatcaca ataagctaaa cctttagctc ctaaggatga tttatctgct tgcttggggg
      541 tcgcttcaaa aaatttcctt ctcacatgcg cccaacatcc aacaagttca gcttcttcca
      601 gttgacgata agcttctagc agttcgcagt ttaccaagct tagcgtcgcc ttgctcctaa
      661 accttggact gctatcgcat aggcagaact agaggactaa agtcctaagt tactgccgca
      721 acatatcaca atgaacatag ccagaataat ctcctaggaa ttcttgtact accgaaccac
      781 tccgactctg atcatgatgg tacagcgtga ttgcttgatt ctcaactttc ccagacaaaa
      841 aggtccaata gtaggtcaga tggctatgac tctctagaac ccgataagaa gtttcatccg
      901 catgaagtaa gggctgagtc aatagtctct ctcgcaagag gttataaagg ggctttagga
      961 ataggagctt tcacaagctt atccagatga ttatctttta ctcgttatgg acaatgctat
     1021 atggcataaa tcaagtacct taaagattcc gactaatatt ggttttgcat ttattcctcc
     1081 atacacacca gagatgaacc ccattgaaca agtgtggaaa gagattcgta aacgtggatt
     1141 tatagtaaaa tgaaataata acaggacaaa tcattcagga cagtcaaatc gatttctaac
     1201 aatgttttag aagcagaggt gtactattct agtttcaatc tactatagat aaacttttga
     1261 gctattcaga agacttgaaa caccactata atctctatca actcttgctt tttcactttc
     1321 agaataagga gcctgacaaa tttttcggac tcattgagga caatctgaat caggttcatc
     1381 ctctaaaacc ttcctcaaag ataaagagaa gattgtcaa
//
LOCUS       DAVBBO010000101         1389 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ST1
            SAMEA2066453-rid20184263.denovo.101, whole genome shotgun sequence.
ACCESSION   DAVBBO010000101 DAVBBO010000000
VERSION     DAVBBO010000101.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2066453
            Sequence Read Archive: ERR351777
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1389)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1389)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980402.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980402.1
            Genome Coverage       :: 176x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:17:33
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,141
            CDSs (total)                      :: 2,104
            Genes (coding)                    :: 1,953
            CDSs (with protein)               :: 1,953
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 16S)
            partial rRNAs                     :: 1 (23S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 151
            CDSs (without protein)            :: 151
            Pseudo Genes (ambiguous residues) :: 0 of 151
            Pseudo Genes (frameshifted)       :: 73 of 151
            Pseudo Genes (incomplete)         :: 76 of 151
            Pseudo Genes (internal stop)      :: 40 of 151
            Pseudo Genes (multiple problems)  :: 32 of 151
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1389
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2066453-rid20184263.denovo.101"
                     /strain="ST1"
                     /db_xref="taxon:1313"
     gene            complement(704..1389)
                     /locus_tag="VQU30_002112"
                     /pseudo
     CDS             complement(704..1389)
                     /locus_tag="VQU30_002112"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000436393.1"
                     /note="frameshifted; internal stop; incomplete; missing
                     N-terminus; Derived by automated computational analysis
                     using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
BASE COUNT          386 a          283 c          287 g          433 t
ORIGIN      
        1 tacgtgacag agtccagttc tatcagaccg ttcgttttac agacacaagt gaagtaggat
       61 tacttcgatt agttgtttac cccttcgctc cacttccatt acagaagttt cctcactact
      121 atgggctcgg ctgacttctc atgattcgtt gttactacgc tttcggcgct catgagacct
      181 cacgggataa gccgtacatc tttcctcgtt tatacaagat atgaggacgt taaaaggtta
      241 caatgaaaat aggaaatctg acgcagagtc tttagactct aggaagattt atctttttca
      301 catagacctt agtccgaatt caattactct cgtgatttac gcatataggt tacgactacc
      361 tttttggact ttagagtttt aagccccctt atccgctgta tacgccttac tatcacgttc
      421 ctgttcgtag agcctcgatt tcgctatccc ttcctctgac gattcttatt tcctgcgtca
      481 gacttaaaac ggtctatccc cagaccgttt taatccgcta cctcacgata gtcaggcttg
      541 ggaatcgcta ttgggttcac cggtagcagg tgcccacgga ggacttacac ctcagatgca
      601 cgacatgccc gtcgtactta aaatcagcct aaatgattca ggctgatttt tctattgatt
      661 caaaaaaacg gctctttgtc aactgtagtg ggttgaagaa aagctaagat cgagaaagga
      721 caaatttcgt cctttctttt ttgatattca gagcgataaa aatccgtttt ttgaagtttt
      781 caaagttccg aaaaccaaag gcattgtgct tgataagttt gatgagatta ttggtcgctt
      841 ccaatttggc gtttgaatag ggtagttgaa gggcgttgat aatcttttct ttatctttga
      901 ggaaggtttt aaagacagtc tgaaaaatag gatgaacctg cttcagattg tcctcaataa
      961 gtccgaaaaa tttctctggt tccttattct ggaagtgaaa aagcaagagc tgatagagct
     1021 gatagtggtg tttcaagtct tccgaatagc tcaaaagctt gtctaaaatc tctttattgg
     1081 ttaaatgcat acgaaaagta ggacgataaa aacgcttatc actcagttta cggctatcct
     1141 gttgtatgag cttccagtag cgcttgatag ccttgtattc atgggatttt cgatgaaact
     1201 gattcatgat ttaaacacgc acacgactca tagcacggct aagatgttgc acaatgtgaa
     1261 agcgatcaag aacgatttta gcattcggga gtgaaacagt ctgggagact gtttcagcct
     1321 gagcctagaa atttgaaagc gaagctgtct agctaagtca tagtaagggc taaacatatc
     1381 catagtaat
//
LOCUS       DAVBBO010000102         1190 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ST1
            SAMEA2066453-rid20184263.denovo.102, whole genome shotgun sequence.
ACCESSION   DAVBBO010000102 DAVBBO010000000
VERSION     DAVBBO010000102.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2066453
            Sequence Read Archive: ERR351777
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1190)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1190)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980402.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980402.1
            Genome Coverage       :: 176x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:17:33
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,141
            CDSs (total)                      :: 2,104
            Genes (coding)                    :: 1,953
            CDSs (with protein)               :: 1,953
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 16S)
            partial rRNAs                     :: 1 (23S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 151
            CDSs (without protein)            :: 151
            Pseudo Genes (ambiguous residues) :: 0 of 151
            Pseudo Genes (frameshifted)       :: 73 of 151
            Pseudo Genes (incomplete)         :: 76 of 151
            Pseudo Genes (internal stop)      :: 40 of 151
            Pseudo Genes (multiple problems)  :: 32 of 151
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1190
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2066453-rid20184263.denovo.102"
                     /strain="ST1"
                     /db_xref="taxon:1313"
     gene            239..>1190
                     /locus_tag="VQU30_002113"
     CDS             239..>1190
                     /locus_tag="VQU30_002113"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001155321.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="HET2448139.1"
                     /translation="MQEHYTPKGKHLTIDNRRLIERWKNENKSNREIAGLLGKAPQTI
                     HNEVKRGTTLQQVRKGLYKKVYSADYAQTVYQFNRKRSVKKLILTKEIREKILHYHKQ
                     KFSPEMMVNKKQVKVGISTIYYWFHNGHLGLTKADMLYPRKRKGVKKQASPNFKPAGK
                     SIEERPDVINLRLENGHYEIDTVLLTKIKNYCLLVLTDRRSRHQIIRLIPNKTAESVN
                     QALTLLLGEHRILSITADNGSEFKRLSEVFPEEHIYYAHAYSSWERGSNENHNRLIRR
                     WLPKGTKKTTPKEVAFIENWINNYPKKCLDYKSPSEFLLGG"
BASE COUNT          413 a          210 c          249 g          318 t
ORIGIN      
        1 agccacctta ccttagtcaa gaattagatg tttcactatg tttgagtaag ttgatgattt
       61 catttgataa caggtttgaa actgttaggc taggtggcca aggctaatca tagccttggt
      121 ttagctgaaa aaacaggttc aagggttcct gttgtcaaat gaaatgtgat ttaaggtata
      181 agaaaacacc tctgtgctat acttgttgtt caccacaaac acaaggaaag gcacagagat
      241 gcaagaacat tataccccaa aagggaaaca tttgacaata gataaccgtc gcttgattga
      301 gcggtggaag aatgaaaata agtccaatcg tgaaattgca ggcttgttag gaaaggcgcc
      361 tcaaacgatt cataatgaag tcaaaagagg tacaacttta caacaagtga gaaaagggct
      421 atacaaaaag gtctattctg ccgattacgc acaaactgtt taccaattca atcgaaaacg
      481 gtcggtgaaa aagttaattt taacaaagga aatcagagag aagatcttac actatcataa
      541 gcaaaaattt tcgcctgaaa tgatggttaa caagaagcaa gtgaaagttg gtatttcaac
      601 catctactac tggtttcata atggtcattt aggattgacg aaggccgaca tgctttatcc
      661 cagaaaaagg aaaggtgtca agaagcaagc tagtccgaac tttaagccgg caggtaaatc
      721 tatcgaagaa cgtcctgacg ttattaatct tcgcttggaa aatggtcatt atgaaattga
      781 taccgtccta ctgactaaga taaaaaatta ttgcctgtta gtcttaaccg accggcggag
      841 cagacaccaa attataaggt taattccaaa taaaactgct gaatctgtca atcaggcgct
      901 tacgttacta ttaggggagc atcgtattct gtccattact gcagataatg gttcggagtt
      961 caaacgattg tctgaggtat ttcctgagga acatatctac tacgcacatg cttactcttc
     1021 atgggagaga ggttcaaatg aaaatcataa tcgattaatt cggagatggt tacctaaagg
     1081 aaccaagaaa acgactccga aagaagtagc ttttatcgaa aattggatta acaactaccc
     1141 taaaaaatgc ttggactaca agtcgccaag tgaatttctt ttgggtggct
//
LOCUS       DAVBBO010000103         1142 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ST1
            SAMEA2066453-rid20184263.denovo.103, whole genome shotgun sequence.
ACCESSION   DAVBBO010000103 DAVBBO010000000
VERSION     DAVBBO010000103.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2066453
            Sequence Read Archive: ERR351777
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1142)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1142)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980402.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980402.1
            Genome Coverage       :: 176x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:17:33
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,141
            CDSs (total)                      :: 2,104
            Genes (coding)                    :: 1,953
            CDSs (with protein)               :: 1,953
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 16S)
            partial rRNAs                     :: 1 (23S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 151
            CDSs (without protein)            :: 151
            Pseudo Genes (ambiguous residues) :: 0 of 151
            Pseudo Genes (frameshifted)       :: 73 of 151
            Pseudo Genes (incomplete)         :: 76 of 151
            Pseudo Genes (internal stop)      :: 40 of 151
            Pseudo Genes (multiple problems)  :: 32 of 151
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1142
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2066453-rid20184263.denovo.103"
                     /strain="ST1"
                     /db_xref="taxon:1313"
     gene            <1..1122
                     /gene="rlmD"
                     /locus_tag="VQU30_002114"
     CDS             <1..1122
                     /gene="rlmD"
                     /locus_tag="VQU30_002114"
                     /EC_number="2.1.1.190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (uracil(1939)-C(5))-methyltransferase
                     RlmD"
                     /protein_id="HET2448140.1"
                     /translation="CGGCQIMHLHYDKQLEFKTDLLHQALKKFAPAGYENYEIRPTIG
                     MQEPKYYRAKLQFQTRKFKNQVKAGLYAQNSHYLVELKDCLVQDKETQVIANRLAELL
                     TYHQIPITDERKVLGVRTIMVRRARKTGQVQIIIVTNRQLNLTQLVKELVKDFPEVVT
                     VAVNTNTAKTSEIYGEKTEIIWGQESIQEGVLNYEFSLSPRAFYQLNPEQTEVLYSEA
                     VKALDVDKEDHLIDAYCGVGTIGFAFAKKVKTLRGMDIIPEAIEDAKRNAKRMGFDNT
                     HYEAGTAEEIIPRWYKEGYRADALIVDPPRTGLDDKLLDTILTYVPEKMVYISCNVST
                     LARDLVRLVEVYDLHYIQSVDMFPHTARTEAVVKLIKKV"
BASE COUNT          387 a          196 c          243 g          316 t
ORIGIN      
        1 tgcggaggct gccaaatcat gcacctgcat tatgataagc agctggagtt caagacggac
       61 ttacttcatc aagcgctgaa aaaatttgct cctgcaggat atgaaaatta tgaaattcgt
      121 ccaactattg gaatgcagga accaaaatat tacagagcta agttacaatt tcagactcga
      181 aaatttaaaa atcaggtcaa ggcgggctta tatgcacaaa actctcacta tttagtagag
      241 ttgaaagact gcctggtaca agataaggaa acccaagtga ttgctaatcg cttagcagaa
      301 ttacttactt atcaccagat tccaatcacg gatgagagaa aagttctagg tgtccgtact
      361 attatggtcc gacgcgcgag aaagaccgga caggttcaga ttattattgt tacaaaccgc
      421 cagcttaatt taactcaatt ggtaaaagag ttggttaaag atttcccaga agttgtgaca
      481 gtagctgtta atacaaatac agctaaaacc agtgagatat atggtgaaaa gacagagatt
      541 atctgggggc aagagagtat tcaagaaggt gtactcaatt atgaattttc actatcccct
      601 cgagcttttt atcaactaaa tcctgagcaa acagaagtcc tctatagcga agcagtaaaa
      661 gcgctggatg ttgataaaga agaccatttg attgacgctt attgtggagt tggaacgatt
      721 ggatttgcct ttgcaaagaa agtaaaaaca ctcagaggta tggatattat tccagaagct
      781 attgaagatg ccaagcgaaa tgctaaaaga atgggatttg acaatactca ttatgaagct
      841 ggaacggcag aagagattat tcctcgttgg tacaaggaag gctaccgagc agatgctttg
      901 attgttgacc caccacgtac aggtctggat gataagttat tagatactat tcttacttat
      961 gtaccagaaa aaatggttta tatttcttgt aatgtttcga ccttggctcg tgatttggta
     1021 cgcttagtag aagtctatga tcttcattat atccagtcgg tcgatatgtt cccacataca
     1081 gctcgaactg aagctgttgt aaaattaata aaaaaagttt aaaaaaggtg ttgacaaaac
     1141 at
//
LOCUS       DAVBBO010000104         1056 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ST1
            SAMEA2066453-rid20184263.denovo.104, whole genome shotgun sequence.
ACCESSION   DAVBBO010000104 DAVBBO010000000
VERSION     DAVBBO010000104.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2066453
            Sequence Read Archive: ERR351777
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1056)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1056)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980402.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980402.1
            Genome Coverage       :: 176x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:17:33
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,141
            CDSs (total)                      :: 2,104
            Genes (coding)                    :: 1,953
            CDSs (with protein)               :: 1,953
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 16S)
            partial rRNAs                     :: 1 (23S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 151
            CDSs (without protein)            :: 151
            Pseudo Genes (ambiguous residues) :: 0 of 151
            Pseudo Genes (frameshifted)       :: 73 of 151
            Pseudo Genes (incomplete)         :: 76 of 151
            Pseudo Genes (internal stop)      :: 40 of 151
            Pseudo Genes (multiple problems)  :: 32 of 151
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1056
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2066453-rid20184263.denovo.104"
                     /strain="ST1"
                     /db_xref="taxon:1313"
     gene            complement(1..113)
                     /locus_tag="VQU30_002115"
                     /pseudo
     CDS             complement(1..113)
                     /locus_tag="VQU30_002115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001153868.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
     gene            complement(565..963)
                     /locus_tag="VQU30_002116"
     CDS             complement(565..963)
                     /locus_tag="VQU30_002116"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000428147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HET2448141.1"
                     /translation="MENKESHKSQEIGNLIRVYNRSKREEAESEPLNLYVEDEKGNLL
                     AGLIAETFGNWLEIEYLFVKEELRGQGIGSKLLQQAESEAKNRNCCFAFVNTYQFQAP
                     DFYQKHGYKEVFSLQDYLYIRQRYYYQKNL"
BASE COUNT          311 a          202 c          165 g          378 t
ORIGIN      
        1 ttgaagcgcc cttttccaag acattgtcgg actgtcctac gcttgatttc agtgtggata
       61 gtttgaggag cttttccaag tagagaggca atttctctat ttgatttccc tttgttcgcc
      121 ttttgtagta taatggtttt gcatctctgt gcctttcttg tgtttgtggt tgaacaacaa
      181 gtataacaca aaggtgtttt cttatgccta caagagcttt cattatttcc attttctttt
      241 ggatttcact ctattctgaa aaacttgtgt atatttactg aagctagcaa gtcttacctg
      301 taaatttaat gaaagcaaca caaaatccga gaggggaatc tcggattaat gtcaatttaa
      361 aaagatagag agtttttagt ttaaataaat tgttttaaaa tatcaacaac atcacttctt
      421 ttcttaacct gataagcctt gattcctaat tttggggcta cgattatatt gtcctcaata
      481 tcgtctagaa agacacaatt tctaggttat aactggtatt tatcgatagt tactcatata
      541 tatcagtcca cctccatact caccttacag attcttttga taataatatc tttgcctaat
      601 gtagagatag tcttgcaaag aaaaaacttc cttgtagcca tgtttctgat aaaagtccgg
      661 tgcctggaac tggtaagtat tgacaaaggc aaaacaacaa tttcgattct tagcttcact
      721 ttctgcctgt tgcaatagtt ttgaaccgat tccttgccct cgcagttcct cttttacaaa
      781 caaatactcg atttctagcc aatttccaaa agtctctgct atcaaacccg caaggagatt
      841 gcccttttca tcttcgacat aaagattaag tggctcactt tcagcctctt ctctttttga
      901 acggttataa acacgaatca gattccctat ttcttgcgat ttatgtgatt ccttattttc
      961 caatctaaag tataatgaaa tgaaataaaa catgcgcaaa tcgattaagg aatttaatct
     1021 aatttctaac aatgtcttag aaatcaaagt gtacta
//
LOCUS       DAVBBO010000105         1054 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ST1
            SAMEA2066453-rid20184263.denovo.105, whole genome shotgun sequence.
ACCESSION   DAVBBO010000105 DAVBBO010000000
VERSION     DAVBBO010000105.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2066453
            Sequence Read Archive: ERR351777
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1054)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1054)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980402.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980402.1
            Genome Coverage       :: 176x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:17:33
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,141
            CDSs (total)                      :: 2,104
            Genes (coding)                    :: 1,953
            CDSs (with protein)               :: 1,953
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 16S)
            partial rRNAs                     :: 1 (23S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 151
            CDSs (without protein)            :: 151
            Pseudo Genes (ambiguous residues) :: 0 of 151
            Pseudo Genes (frameshifted)       :: 73 of 151
            Pseudo Genes (incomplete)         :: 76 of 151
            Pseudo Genes (internal stop)      :: 40 of 151
            Pseudo Genes (multiple problems)  :: 32 of 151
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1054
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2066453-rid20184263.denovo.105"
                     /strain="ST1"
                     /db_xref="taxon:1313"
     gene            <1..555
                     /locus_tag="VQU30_002117"
     CDS             <1..555
                     /locus_tag="VQU30_002117"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001220748.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HET2448142.1"
                     /translation="KDETTSYPIYEIPEAWRYIKFASLVNFRIGKTPPRSEATFWGTE
                     IPWVSISDMPISGYVTNTRESISKLALKSKKIDISPKGTLLMSFKLSIGKVAILDIPA
                     THNEAIISIFPYANKENIIRDYLMIFLPLISTLGDSKDAIKGKTLNSTSISELLIPIS
                     NHEEMKRIISKVDLLFQKVSQLFE"
     gene            complement(503..1048)
                     /locus_tag="VQU30_002118"
     CDS             complement(503..1048)
                     /locus_tag="VQU30_002118"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001104691.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HET2448143.1"
                     /translation="MNWVVIKIKDIFSINTGLSYKKGDLSINNKGVRIIRGGNIKPLE
                     FSLLDNDYYIDTQFISSEQVYLKHNQLITPVSTSLEHIGKFARIDKDYDGVVAGGFIF
                     QLTPFESSEIISKFLLFNLSSPLFYKQLKAITKLSGQALYNIPKTTLSELLIPLAPFE
                     EQELITQKVEKLFEKVNQLWK"
BASE COUNT          380 a          165 c          153 g          356 t
ORIGIN      
        1 aaagacgaaa caacctctta tcctatatat gaaatcccag aagcatggag atatattaaa
       61 tttgctagcc tagttaactt cagaatagga aaaactcctc cacgcagtga agctactttt
      121 tggggaactg aaataccttg ggtatctata tcagatatgc ctatatctgg ttatgtaact
      181 aatacgagag aatctatttc taaattagca ttaaaatcaa agaaaataga catttcacct
      241 aaaggaactt tattaatgag ttttaaatta tctattggaa aagttgccat attggatatt
      301 cctgccactc ataatgaagc cattatatcg atattcccct atgctaataa agaaaatatt
      361 atcagagatt acttaatgat atttttgcca cttatctcta ctttaggtga ttcaaaagat
      421 gctataaaag ggaaaacatt aaatagtacc agtatctccg aattattaat ccctatttct
      481 aatcatgaag agatgaaaag aatcatttcc aaagttgatt tactttttca aaaagtttct
      541 caactttttg agtaataagt tcctgttcct caaaaggagc taacggaatt aatagctcgc
      601 ttagtgtagt tttaggaata ttatataaag cttgacctga tagtttagtt attgctttca
      661 attgtttata aaataacgga gaggacaagt taaataatag aaattttgaa ataatctctg
      721 aactttcgaa tggtgttaat tggaaaataa atccaccagc cacaacacca tcatagtctt
      781 tatcgattct tgcaaacttt ccaatatgtt ctaaagaggt tgatacaggt gttattagct
      841 gattatgttt taaataaact tgctcagagg agatgaattg tgtatcaatg tagtaatcat
      901 tatccaacag agaaaattct aaaggcttaa tattaccacc acgtataatt ctaacacctt
      961 tattattaat gcttaaatcg cccttcttgt aagaaagacc tgtatttatt gaaaaaatat
     1021 cttttatttt tataacaacc caattcatag gtat
//
LOCUS       DAVBBO010000106         1035 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ST1
            SAMEA2066453-rid20184263.denovo.106, whole genome shotgun sequence.
ACCESSION   DAVBBO010000106 DAVBBO010000000
VERSION     DAVBBO010000106.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2066453
            Sequence Read Archive: ERR351777
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1035)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1035)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980402.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980402.1
            Genome Coverage       :: 176x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:17:33
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,141
            CDSs (total)                      :: 2,104
            Genes (coding)                    :: 1,953
            CDSs (with protein)               :: 1,953
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 16S)
            partial rRNAs                     :: 1 (23S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 151
            CDSs (without protein)            :: 151
            Pseudo Genes (ambiguous residues) :: 0 of 151
            Pseudo Genes (frameshifted)       :: 73 of 151
            Pseudo Genes (incomplete)         :: 76 of 151
            Pseudo Genes (internal stop)      :: 40 of 151
            Pseudo Genes (multiple problems)  :: 32 of 151
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1035
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2066453-rid20184263.denovo.106"
                     /strain="ST1"
                     /db_xref="taxon:1313"
     gene            complement(<1..990)
                     /gene="ltrA"
                     /locus_tag="VQU30_002119"
     CDS             complement(<1..990)
                     /gene="ltrA"
                     /locus_tag="VQU30_002119"
                     /EC_number="2.7.7.49"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000040325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="group II intron reverse transcriptase/maturase"
                     /protein_id="HET2448144.1"
                     /translation="MSKLLDKILSRDNMLEAYNQVKSNKGSAGIDGITIEEMDGYLRQ
                     NWRLTKELIKQRKYKPQPVLRVEIPKPNGGIRQLGIPTVMDRMIQQAIVQVISPICEP
                     HFSDTSYGFRPNRSCEKAIMKLLEYLNDGYEWIVDIDLEKFFDTVPQDRLMSLVHNII
                     EDGDTESLIRKYLHSGVIINGQRYKTLVGTPQGGNLSPLLSNIMLNELDKELEKRGLR
                     FVRYADDCVITVGSEAAAKRVMYSVSRFIEKRLGLKVNMTKTKITRPRELKYLGFGFW
                     KSSDGWKSRPHQDSVWRFKLKLKKLTQRKWSIDLTRRIEQLNLSIRGWINYFSL"
BASE COUNT          270 a          226 c          183 g          356 t
ORIGIN      
        1 caatgagaaa tagtttatcc atcctcgaat agacaaattc agttgctcaa tacgtcttgt
       61 taggtctata ctccatttcc tctgtgttag tttcttcaat ttaagcttaa atctccaaac
      121 actatcttga tgtggacgac ttttccaacc atctgatgat ttccagaacc cgaaacctag
      181 atatttcaac tctcttggtc tggtaatctt agtcttggtc atgtttactt tcagacctag
      241 ccgtttctca ataaaacgac tgactgaata catcacacgc ttagcggctg cctcgcttcc
      301 gaccgtaatc acacaatcgt ctgcgtagcg aacaaatcga agccctctct tttctaattc
      361 cttgtccaat tcattaagca tgatattgga taagagagga gataaatttc ctccctgtgg
      421 cgtgccaact agcgttttat aacgttgacc gttaatgata acacctgaat gaagatattt
      481 acgaatcaag gattccgtat ctccgtcttc gataatgtta tgtactaagg acatcaatct
      541 atcttgagga actgtatcga aaaatttctc taggtctatg tccactatcc actcatagcc
      601 gtcatttaag tactctaaga gcttcatgat ggctttttca catgacctat ttggtctgaa
      661 tccatagctc gtatctgaga aatggggttc acaaataggg ctaataactt gaacaatggc
      721 ctgttgaatc attctatcca taactgttgg aattcctagt tggcggatgc ctccgtttgg
      781 tttgggaatc tcaactctaa gaactggttg aggcttatat tttctctgtt ttatcagttc
      841 cttagtcagg cgccagtttt gtctgagata gccatccatc tcttcgatag taattccatc
      901 aatcccagct gagcctttat tagattttac ttgattgtag gcttcaagca tattgtcgcg
      961 tgataatatt ttatctagca attttgacat gtgcctattc ctttcttgtt ttggtgcctg
     1021 agggacatct tatat
//
LOCUS       DAVBBO010000107          986 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ST1
            SAMEA2066453-rid20184263.denovo.107, whole genome shotgun sequence.
ACCESSION   DAVBBO010000107 DAVBBO010000000
VERSION     DAVBBO010000107.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2066453
            Sequence Read Archive: ERR351777
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 986)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 986)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980402.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980402.1
            Genome Coverage       :: 176x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:17:33
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,141
            CDSs (total)                      :: 2,104
            Genes (coding)                    :: 1,953
            CDSs (with protein)               :: 1,953
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 16S)
            partial rRNAs                     :: 1 (23S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 151
            CDSs (without protein)            :: 151
            Pseudo Genes (ambiguous residues) :: 0 of 151
            Pseudo Genes (frameshifted)       :: 73 of 151
            Pseudo Genes (incomplete)         :: 76 of 151
            Pseudo Genes (internal stop)      :: 40 of 151
            Pseudo Genes (multiple problems)  :: 32 of 151
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..986
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2066453-rid20184263.denovo.107"
                     /strain="ST1"
                     /db_xref="taxon:1313"
     gene            complement(74..147)
                     /locus_tag="VQU30_002120"
     tRNA            complement(74..147)
                     /locus_tag="VQU30_002120"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(111..113),aa:Arg,seq:acg)
     gene            complement(157..242)
                     /locus_tag="VQU30_002121"
     tRNA            complement(157..242)
                     /locus_tag="VQU30_002121"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(206..208),aa:Leu,seq:taa)
     gene            complement(250..321)
                     /locus_tag="VQU30_002122"
     tRNA            complement(250..321)
                     /locus_tag="VQU30_002122"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(287..289),aa:Gly,seq:gcc)
     gene            complement(344..416)
                     /locus_tag="VQU30_002123"
     tRNA            complement(344..416)
                     /locus_tag="VQU30_002123"
                     /product="tRNA-Thr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(381..383),aa:Thr,seq:tgt)
     gene            complement(435..516)
                     /locus_tag="VQU30_002124"
     tRNA            complement(435..516)
                     /locus_tag="VQU30_002124"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(480..482),aa:Leu,seq:tag)
     gene            complement(522..594)
                     /locus_tag="VQU30_002125"
     tRNA            complement(522..594)
                     /locus_tag="VQU30_002125"
                     /product="tRNA-Lys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(559..561),aa:Lys,seq:ttt)
     gene            complement(619..691)
                     /locus_tag="VQU30_002126"
     tRNA            complement(619..691)
                     /locus_tag="VQU30_002126"
                     /product="tRNA-Asp"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(656..658),aa:Asp,seq:gtc)
     gene            complement(694..766)
                     /locus_tag="VQU30_002127"
     tRNA            complement(694..766)
                     /locus_tag="VQU30_002127"
                     /product="tRNA-Val"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(731..733),aa:Val,seq:tac)
     gene            complement(771..886)
                     /gene="rrf"
                     /locus_tag="VQU30_002128"
     rRNA            complement(771..886)
                     /gene="rrf"
                     /locus_tag="VQU30_002128"
                     /product="5S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00001"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00001"
BASE COUNT          251 a          283 c          209 g          243 t
ORIGIN      
        1 cgaacctgcg acaccttggt cccaaaccaa gtactctacc aagctgagct acttcccgag
       61 ttaaatagaa aaatgcaccc tagaggagtc gaacctctaa ccgcctgatt cgtagtcagg
      121 tactctatcc agttgagcta agggtgctcc atattatgcc gaggaccgga atcgaaccgg
      181 tacgatcgtt accaatcgca ggattttaag tcctgtgcgt ctgccagttc cgccaccccg
      241 gcctctctaa gcgaacgacg ggattcgaac ccgcgacccc caccttggca aggtggtgtt
      301 ctaccactga actacgttcg cactgttttc ttctatctaa aaatgccggc tacatgactt
      361 gaacacgcga ccctctgatt acaaatcaga tgctctacca actgagctaa gccggctcat
      421 ttgttatatc ttaatgcggg ttaagggact tgaaccccca cgccgttaag cgccagatcc
      481 taaatctggt gcgtctgcca attccgccaa acccgcatat atgacccgta ctgggctcga
      541 accagtgacc cattgattaa aagtcaattg ctctaccaac tgagctaacg agtctaaaat
      601 aacttgcgtt accttaaacg gtcccgacgg gaatcgaacc cgcgatcttc gccgtgacag
      661 ggcgacgtga taaccgctac actacgggac ctttgggagt taacgggatc gaaccgctga
      721 ccctctgctt gtaaggcaga tgctctccca gctgagctaa actccctaga gctaagcgac
      781 ttccctatct cacagggggc aacccccaac tacttccggc gttctagggc ttaacttctg
      841 tgttcggcat gggtacaggt gtatctccta ggctatcgtc acttaactct gagtaatacc
      901 tactcaaaat cgaatatcta ttcaattcaa gaaaaccgtt cgctttcata ttctcagtta
      961 ctttggataa gtcctcgagc tattag
//
LOCUS       DAVBBO010000108          922 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ST1
            SAMEA2066453-rid20184263.denovo.108, whole genome shotgun sequence.
ACCESSION   DAVBBO010000108 DAVBBO010000000
VERSION     DAVBBO010000108.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2066453
            Sequence Read Archive: ERR351777
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 922)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 922)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980402.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980402.1
            Genome Coverage       :: 176x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:17:33
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,141
            CDSs (total)                      :: 2,104
            Genes (coding)                    :: 1,953
            CDSs (with protein)               :: 1,953
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 16S)
            partial rRNAs                     :: 1 (23S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 151
            CDSs (without protein)            :: 151
            Pseudo Genes (ambiguous residues) :: 0 of 151
            Pseudo Genes (frameshifted)       :: 73 of 151
            Pseudo Genes (incomplete)         :: 76 of 151
            Pseudo Genes (internal stop)      :: 40 of 151
            Pseudo Genes (multiple problems)  :: 32 of 151
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..922
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2066453-rid20184263.denovo.108"
                     /strain="ST1"
                     /db_xref="taxon:1313"
     gene            122..590
                     /locus_tag="VQU30_002129"
                     /pseudo
     CDS             122..590
                     /locus_tag="VQU30_002129"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001817843.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
BASE COUNT          336 a          139 c          172 g          275 t
ORIGIN      
        1 gagaagagga ttgccatctt ctccattttt atgtgcagag ttatagtggc ttgatgctgg
       61 gaaagtacac tgtgactgct aaaacattcc tagaagctgc tttgatttcc ctaatctatt
      121 tatgcaaatt ttatgttatt ttactataac agttgttgct aagccaaata atagtgggga
      181 agttcattta gacgtaagca ttgaagataa tcagggaggt agtgggtata atttcagttc
      241 tgtttcaagt agctcacaaa cagctaaata tgaaggaact ggttataata acaattcatc
      301 attatatata acgattgata aaacgtctga tgcaacagct cttttgaaat taaagttgaa
      361 taatgttgat aatcaacctg ctactgaagt tcctagttca ggaattactg taaaattaaa
      421 tgctaaagat aatgctggaa actggacaag tgcttcgaat aaagacaagt gcttcgaata
      481 aaaaagaaat aacagtaaaa attgtttctg ctaaaccgac atatccagac aaaatcttag
      541 tgaaaaatcc tgataatata aaagatacag aaaaaaatgc cattattgaa aaattgaaag
      601 aggcaaataa aaatcatcca gcaggagctc caacctttgc taaaggtgaa ggagagcatg
      661 caaatgatat tgtagcaact tattcagatg gtacaactta ttatgtaccg ttaaatgatg
      721 tgacaaaata tgcgaggtag tggctgtacc actcacttat tcacctcccc gtgatttgta
      781 gtagtgatag gctttctcac tattattata aaacaaaata aagatcacaa cactttttca
      841 ttctgtgttg tgccttgagt gaaacgaaag gaatgaatta taaatatgaa aagtatagtc
      901 actagcatag atgagcgctt gc
//
LOCUS       DAVBBO010000109          830 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ST1
            SAMEA2066453-rid20184263.denovo.109, whole genome shotgun sequence.
ACCESSION   DAVBBO010000109 DAVBBO010000000
VERSION     DAVBBO010000109.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2066453
            Sequence Read Archive: ERR351777
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 830)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 830)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980402.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980402.1
            Genome Coverage       :: 176x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:17:33
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,141
            CDSs (total)                      :: 2,104
            Genes (coding)                    :: 1,953
            CDSs (with protein)               :: 1,953
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 16S)
            partial rRNAs                     :: 1 (23S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 151
            CDSs (without protein)            :: 151
            Pseudo Genes (ambiguous residues) :: 0 of 151
            Pseudo Genes (frameshifted)       :: 73 of 151
            Pseudo Genes (incomplete)         :: 76 of 151
            Pseudo Genes (internal stop)      :: 40 of 151
            Pseudo Genes (multiple problems)  :: 32 of 151
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..830
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2066453-rid20184263.denovo.109"
                     /strain="ST1"
                     /db_xref="taxon:1313"
     gene            21..830
                     /locus_tag="VQU30_002130"
                     /pseudo
     CDS             21..830
                     /locus_tag="VQU30_002130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_086558050.1"
                     /note="frameshifted; incomplete; missing C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS5-like element IS1515 family transposase"
BASE COUNT          266 a          174 c          162 g          228 t
ORIGIN      
        1 aaaagtgtta tactattttt atggaaacag tatacgacaa agcacaaaaa cttaactcaa
       61 aaaacttcaa actattgatt ggtgtcaaaa aggaaacctt tcaactcatg ctagaacacc
      121 tgaattcagc ctatcagatt cagcaccgaa aaggtggacg tccacgtagt ctgcccatgg
      181 aagaccagct cattatgacc ctccgttact tgcgatatta tcccactcag cgtctgctgg
      241 cctttgattt tggcgtcggt gtagctacgg taaatgccat catcacttgg gtggaggata
      301 cacttcgtgc gtcaggtagc tttgatttgg accatttaga agccccgagt gctgctgtgg
      361 ctattgacgt gaccgaaagt ccgattcagc gtccaaaaaa aaccaaagca aaaattattc
      421 tggtaaaaag aaacgacaca ccttaaaaac tcaaattatg ctggatttga cgacacataa
      481 agtctgtcaa atggcctttt ctgacggaca tacgcatgat tttactctct tcaaagaaag
      541 tattggacaa agtttgcctg aaacgacgct tgcctttgtt gacctaggtt atttaggcat
      601 cttgaaattt catgagaata ctttcattcc tgctaaaaat tccaaaaatc gccgcctgag
      661 tgaggatgat aagcagttaa ataaagagat gtcagcgata cgaattgaaa ttgaacattt
      721 taacgctaaa ttcaagacct tccaaatcat gtcagtccct tatcgtaacc gcagaaaacg
      781 tttcgagtta cgggcggaat taatttgtgc catcatcaat tatgaagtga
//
LOCUS       DAVBBO010000110          611 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ST1
            SAMEA2066453-rid20184263.denovo.110, whole genome shotgun sequence.
ACCESSION   DAVBBO010000110 DAVBBO010000000
VERSION     DAVBBO010000110.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2066453
            Sequence Read Archive: ERR351777
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 611)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 611)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980402.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980402.1
            Genome Coverage       :: 176x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:17:33
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,141
            CDSs (total)                      :: 2,104
            Genes (coding)                    :: 1,953
            CDSs (with protein)               :: 1,953
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 16S)
            partial rRNAs                     :: 1 (23S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 151
            CDSs (without protein)            :: 151
            Pseudo Genes (ambiguous residues) :: 0 of 151
            Pseudo Genes (frameshifted)       :: 73 of 151
            Pseudo Genes (incomplete)         :: 76 of 151
            Pseudo Genes (internal stop)      :: 40 of 151
            Pseudo Genes (multiple problems)  :: 32 of 151
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..611
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2066453-rid20184263.denovo.110"
                     /strain="ST1"
                     /db_xref="taxon:1313"
     gene            complement(189..>611)
                     /locus_tag="VQU30_002131"
     CDS             complement(189..>611)
                     /locus_tag="VQU30_002131"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000700331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine motif-containing protein"
                     /protein_id="HET2448145.1"
                     /translation="KPNEEKPQTEKPEEDKEHDEVSEPTHPESDEKENHAGLNPSADN
                     LYKPSTDTEETEEEAEDTTDEAEIPQVEHSVINAKIAEAEALLEKVTDSSIRQNAVET
                     LTGLKSSLLLGTKDNNTISAEVDSLLALLKESQPTPIQ"
BASE COUNT          155 a          121 c           93 g          242 t
ORIGIN      
        1 gatgaagttt tttctcaact tcttttactt tattaaatag ttttctaaac cggttattta
       61 accatttaat taaccagtaa atagtttact atttaaaatt acttttgtca agtttctgtt
      121 acgtttttct aaaaaagaga agtaacacga aaggttactt ctccataaaa tatgctccat
      181 tcattttact actgtatagg agtcggttga ctttctttta acaaagccaa gagactatct
      241 acttctgctg aaatagtgtt attatctttc gttccgagaa gaagactact ttttagacca
      301 gtcaatgtct ccacagcatt ttgtctaata ctagaatctg ttactttttc tagcaaggcc
      361 tccgcctctg ctatcttagc gttaataaca gaatgctcta cttgaggaat ttcagcctca
      421 tctgtagtat cttcagcttc ttcctctgtc tcttccgtat cagtgcttgg tttataaaga
      481 ttatctgctg aaggatttaa accagcgtga ttctcttttt catcagattc agggtgagtt
      541 ggctcactta cttcatcatg ttccttatct tcctcaggtt tttctgtctg aggtttctcc
      601 tcgtttggtt t
//
LOCUS       DAVBBO010000111          595 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ST1
            SAMEA2066453-rid20184263.denovo.111, whole genome shotgun sequence.
ACCESSION   DAVBBO010000111 DAVBBO010000000
VERSION     DAVBBO010000111.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2066453
            Sequence Read Archive: ERR351777
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 595)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 595)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980402.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980402.1
            Genome Coverage       :: 176x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:17:33
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,141
            CDSs (total)                      :: 2,104
            Genes (coding)                    :: 1,953
            CDSs (with protein)               :: 1,953
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 16S)
            partial rRNAs                     :: 1 (23S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 151
            CDSs (without protein)            :: 151
            Pseudo Genes (ambiguous residues) :: 0 of 151
            Pseudo Genes (frameshifted)       :: 73 of 151
            Pseudo Genes (incomplete)         :: 76 of 151
            Pseudo Genes (internal stop)      :: 40 of 151
            Pseudo Genes (multiple problems)  :: 32 of 151
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..595
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2066453-rid20184263.denovo.111"
                     /strain="ST1"
                     /db_xref="taxon:1313"
     gene            complement(1..595)
                     /locus_tag="VQU30_002132"
                     /pseudo
     CDS             complement(1..595)
                     /locus_tag="VQU30_002132"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677188.1"
                     /note="frameshifted; incomplete; missing N-terminus and
                     C-terminus; Derived by automated computational analysis
                     using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
BASE COUNT          192 a          103 c          127 g          173 t
ORIGIN      
        1 tgaaaaagca agagttgata gagttgatag tggtgtttca agtcttccga ataactcaaa
       61 agcttgttta aaatctcttt attggttaag tgcatacgaa aagtaggacg ataaaaacgt
      121 ttatcactca gtttacggct atcctgttga atgagtttcc agtagcgctt gatagccttg
      181 tattcatggg attttcgatg aaactgattc atgatttgga cacgcacacg actcatagca
      241 cggctaagat gttgtacaat atgaaagcga tcaagaacga ttttagcatt cgggagtgaa
      301 acagtctggg agactgtttc agcctgagcc tagaaatttg aaagcgaagc tgtttagcca
      361 agtcatagta agggctaaac atatccatag taatgatttt gacgcgacat cggacggctc
      421 tatcatattt aagaaagtga tttcgaatga tagcttgtgt tcttccctca agaacagtga
      481 tgatattgag attgttaaaa tcttgcgcaa tgaagctcat ctttcccttt gtaaaagcat
      541 actcatccca agacataatc tcaggaagac gcgaaaaatc atgctcaaag tgaaa
//
LOCUS       DAVBBO010000112          569 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ST1
            SAMEA2066453-rid20184263.denovo.112, whole genome shotgun sequence.
ACCESSION   DAVBBO010000112 DAVBBO010000000
VERSION     DAVBBO010000112.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2066453
            Sequence Read Archive: ERR351777
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 569)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 569)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980402.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980402.1
            Genome Coverage       :: 176x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:17:33
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,141
            CDSs (total)                      :: 2,104
            Genes (coding)                    :: 1,953
            CDSs (with protein)               :: 1,953
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 16S)
            partial rRNAs                     :: 1 (23S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 151
            CDSs (without protein)            :: 151
            Pseudo Genes (ambiguous residues) :: 0 of 151
            Pseudo Genes (frameshifted)       :: 73 of 151
            Pseudo Genes (incomplete)         :: 76 of 151
            Pseudo Genes (internal stop)      :: 40 of 151
            Pseudo Genes (multiple problems)  :: 32 of 151
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..569
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2066453-rid20184263.denovo.112"
                     /strain="ST1"
                     /db_xref="taxon:1313"
     gene            complement(<1..>569)
                     /locus_tag="VQU30_002133"
     CDS             complement(<1..>569)
                     /locus_tag="VQU30_002133"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2448146.1"
                     /translation="AEALVDAEADALVEADSEAEVLAEADALVDAEADALVLAEADAL
                     VDAEADALVLAEAEALVDAEADALVLAEAEALVDAEADALVLAEADALVLAEAEALVD
                     AEAEALVDADSEALVDAEADALIDADSEADVLAEAEALVDAEAEALVDADSEALVDAE
                     AEADVDAEADALVDAEADALVDAEAEALV"
BASE COUNT          137 a          187 c          130 g          115 t
ORIGIN      
        1 tcaaccagcg cctcagcttc agcatcaacg agtgcgtcgg cttcagcatc aacgagtgca
       61 tcggcttcag catcaacgtc tgcctcagct tcagcgtcaa ccagtgcctc tgaatcggca
      121 tcaaccagtg cttcagcctc agcatcgaca agcgcttcgg cttcagcaag tacatcagct
      181 tctgaatctg catcaataag tgcgtcggct tcagcgtcaa ccagtgcctc tgaatcggca
      241 tcaaccagtg cttcagcctc agcatcaacg agtgcttcgg cttcagcaag tacaagtgcg
      301 tcagcttcag caagcacaag tgcgtcagct tcagcatcaa cgagcgcctc ggcttcagca
      361 agcaccagtg cgtcagcttc agcatcaacg agtgcctcgg cctcagcaag tacaagtgcg
      421 tcagcctcag catcaaccag tgcatcagcc tcagcaagta ccagtgcatc agcttccgca
      481 tcaacgagtg catcagcctc agcaagcacc tcagcttctg aatcggcctc aacgagtgcg
      541 tcagcctcag cgtcaacgag tgcttcggc
//
LOCUS       DAVBBO010000113          489 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ST1
            SAMEA2066453-rid20184263.denovo.113, whole genome shotgun sequence.
ACCESSION   DAVBBO010000113 DAVBBO010000000
VERSION     DAVBBO010000113.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2066453
            Sequence Read Archive: ERR351777
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 489)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 489)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980402.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980402.1
            Genome Coverage       :: 176x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:17:33
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,141
            CDSs (total)                      :: 2,104
            Genes (coding)                    :: 1,953
            CDSs (with protein)               :: 1,953
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 16S)
            partial rRNAs                     :: 1 (23S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 151
            CDSs (without protein)            :: 151
            Pseudo Genes (ambiguous residues) :: 0 of 151
            Pseudo Genes (frameshifted)       :: 73 of 151
            Pseudo Genes (incomplete)         :: 76 of 151
            Pseudo Genes (internal stop)      :: 40 of 151
            Pseudo Genes (multiple problems)  :: 32 of 151
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..489
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2066453-rid20184263.denovo.113"
                     /strain="ST1"
                     /db_xref="taxon:1313"
     gene            <1..>489
                     /locus_tag="VQU30_002134"
     CDS             <1..>489
                     /locus_tag="VQU30_002134"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019770457.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="IS110 family transposase"
                     /protein_id="HET2448147.1"
                     /translation="KKDAHGIALKLLSDPNREQFQHDNRQVELKILARHIHRLKKKQS
                     DWKVQYTRCLDIIFPELDKIVEKHSEYTYQLLTCYPNPQKRLEAGFDKLIEIKRLTAS
                     KIQDILSVAPRSIGTTSPAREFEIIKHYKRLIDKAETCVNDLMAEFNSVITTVTGIGN
                     RL"
BASE COUNT          158 a          106 c           93 g          132 t
ORIGIN      
        1 ataagaaaga cgctcatggc atcgctctta aacttctttc tgaccccaat cgtgaacaat
       61 ttcaacacga taatcggcaa gtagaactaa aaatactggc tagacatatt catcgtctca
      121 agaaaaaaca gtctgattgg aaagtacaat acactcgttg tcttgatatc atctttcctg
      181 agttggataa aatcgttgaa aagcattcag aatataccta ccaactcttg acatgctacc
      241 ctaatcctca gaaaaggctt gaggcaggat ttgataagct gatagaaatt aagcgattga
      301 ccgcttctaa aattcaggat atcctctcag ttgcacctcg ttctatcgga acaacatctc
      361 ctgctcgtga attcgaaatc atcaaacatt acaagaggct cattgacaag gcggaaacat
      421 gtgtcaatga cttgatggct gagttcaact cggtcatcac gacggtcact gggattggga
      481 atcgtttag
//
LOCUS       DAVBBO010000114          482 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ST1
            SAMEA2066453-rid20184263.denovo.114, whole genome shotgun sequence.
ACCESSION   DAVBBO010000114 DAVBBO010000000
VERSION     DAVBBO010000114.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2066453
            Sequence Read Archive: ERR351777
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 482)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 482)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980402.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980402.1
            Genome Coverage       :: 176x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:17:33
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,141
            CDSs (total)                      :: 2,104
            Genes (coding)                    :: 1,953
            CDSs (with protein)               :: 1,953
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 16S)
            partial rRNAs                     :: 1 (23S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 151
            CDSs (without protein)            :: 151
            Pseudo Genes (ambiguous residues) :: 0 of 151
            Pseudo Genes (frameshifted)       :: 73 of 151
            Pseudo Genes (incomplete)         :: 76 of 151
            Pseudo Genes (internal stop)      :: 40 of 151
            Pseudo Genes (multiple problems)  :: 32 of 151
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..482
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2066453-rid20184263.denovo.114"
                     /strain="ST1"
                     /db_xref="taxon:1313"
     gene            complement(<1..>482)
                     /locus_tag="VQU30_002135"
     CDS             complement(<1..>482)
                     /locus_tag="VQU30_002135"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2448148.1"
                     /translation="EALVLAEADALVLAETEALVLAEAEALVDAEAEALVLAEAEALV
                     DADSDAEVLAEAEALVDAEAEALVLAEAEALVLADSDALVDAEAEALVDAEAEALVDA
                     EADALVDAEAEALVDAEAEALVDAEAEALVLAEADALVDAEAEALVLAEADALVEAEA
                     "
BASE COUNT          120 a          161 c          106 g           95 t
ORIGIN      
        1 tcagcttcgg cctcaacaag tgcgtcagct tcagcaagca ccagtgcttc ggcttcagcg
       61 tcgacaagtg cgtcagcctc agcaagcacc agtgcctcag cttcagcatc aacaagtgct
      121 tcagcctcag cgtcaacaag tgcttcagct tcagcatcaa caagtgcgtc agcttcagca
      181 tcaaccagtg cctcagcctc agcgtcgaca agtgcctcgg cttcagcatc gacaagtgca
      241 tctgaatcag caagcacaag tgcttcagct tcagcaagta ccagcgcctc agcctcagca
      301 tcaaccagtg cttcggcttc agcaagtacc tcagcgtctg aatcggcatc aacaagtgct
      361 tcagcttcag caagtacaag cgcctcagct tcagcatcaa ccagtgcttc ggcttcagca
      421 agcaccagtg cctcagtctc agcaagcacc agtgcgtcgg cttcagcaag cacaagcgcc
      481 tc
//
LOCUS       DAVBBO010000115          430 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ST1
            SAMEA2066453-rid20184263.denovo.115, whole genome shotgun sequence.
ACCESSION   DAVBBO010000115 DAVBBO010000000
VERSION     DAVBBO010000115.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2066453
            Sequence Read Archive: ERR351777
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 430)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 430)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980402.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980402.1
            Genome Coverage       :: 176x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:17:33
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,141
            CDSs (total)                      :: 2,104
            Genes (coding)                    :: 1,953
            CDSs (with protein)               :: 1,953
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 16S)
            partial rRNAs                     :: 1 (23S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 151
            CDSs (without protein)            :: 151
            Pseudo Genes (ambiguous residues) :: 0 of 151
            Pseudo Genes (frameshifted)       :: 73 of 151
            Pseudo Genes (incomplete)         :: 76 of 151
            Pseudo Genes (internal stop)      :: 40 of 151
            Pseudo Genes (multiple problems)  :: 32 of 151
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..430
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2066453-rid20184263.denovo.115"
                     /strain="ST1"
                     /db_xref="taxon:1313"
     gene            321..>430
                     /locus_tag="VQU30_002136"
     CDS             321..>430
                     /locus_tag="VQU30_002136"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000242196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIBC"
                     /protein_id="HET2448149.1"
                     /translation="MVLDYFFDKNLVFCLEADNQEQLFDQVATLLEEREIV"
BASE COUNT          152 a           59 c           78 g          141 t
ORIGIN      
        1 ctaatctgga gatttttcaa tagacttcgt tattgggcgg ttacgatatg atcactgact
       61 tcgtcagtct tatctacaac ctcaaaactg tgttttgagc aacctgcggc tagcttccta
      121 gtttgctctt tgattttcat tgagtattag aacagaaaaa atacttggag tatttgtttg
      181 tgtgtttatt tttatataac aaactataaa caaaacaaaa atataaaaaa agagacaaaa
      241 aagaacagaa agcaattgac aacggtttca tatagtgtta tacttatggc ataaagttaa
      301 tggaaagaag ggaaaaactt atggtattag attatttctt tgacaaaaac cttgtgtttt
      361 gcttagaagc ggataatcaa gaacaactct ttgatcaggt tgcaacttta ttggaagaac
      421 gagaaattgt
//
LOCUS       DAVBBO010000116          393 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ST1
            SAMEA2066453-rid20184263.denovo.116, whole genome shotgun sequence.
ACCESSION   DAVBBO010000116 DAVBBO010000000
VERSION     DAVBBO010000116.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2066453
            Sequence Read Archive: ERR351777
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 393)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 393)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980402.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980402.1
            Genome Coverage       :: 176x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:17:33
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,141
            CDSs (total)                      :: 2,104
            Genes (coding)                    :: 1,953
            CDSs (with protein)               :: 1,953
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 16S)
            partial rRNAs                     :: 1 (23S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 151
            CDSs (without protein)            :: 151
            Pseudo Genes (ambiguous residues) :: 0 of 151
            Pseudo Genes (frameshifted)       :: 73 of 151
            Pseudo Genes (incomplete)         :: 76 of 151
            Pseudo Genes (internal stop)      :: 40 of 151
            Pseudo Genes (multiple problems)  :: 32 of 151
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..393
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2066453-rid20184263.denovo.116"
                     /strain="ST1"
                     /db_xref="taxon:1313"
     gene            <1..>393
                     /locus_tag="VQU30_002137"
     CDS             <1..>393
                     /locus_tag="VQU30_002137"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000588926.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HET2448150.1"
                     /translation="YLHLWELSDWDQEGMLCLHELISREEGLVDDIPRLRKYFKTKFR
                     NRILDYIRKQESQKRRYDKEPYEEVGEISHRISEGGLWLDDYYLFHETLRDYRNKQSK
                     EKQEELERVLSNERFRGRQRVLRDLRIVF"
BASE COUNT          143 a           57 c           93 g          100 t
ORIGIN      
        1 taccttcatt tatgggaatt gtcggattgg gaccaagaag gcatgctctg cttacatgaa
       61 ttgattagta gagaagaagg actggtagac gatattccac gtttaaggaa atatttcaaa
      121 accaagtttc gaaatcgaat tttagactat atccgtaagc aggaaagtca gaagcgtaga
      181 tacgataaag aaccctatga agaagtggga gagatcagtc atcgtataag tgaggggggt
      241 ctctggctag atgattatta tctctttcat gaaacactaa gagattatag aaacaaacaa
      301 agtaaagaga aacaagaaga actagaacgc gtcttaagca atgaacgatt tcgagggcgt
      361 caaagagtat taagagactt acgcattgtg ttt
//
LOCUS       DAVBBO010000117          311 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ST1
            SAMEA2066453-rid20184263.denovo.117, whole genome shotgun sequence.
ACCESSION   DAVBBO010000117 DAVBBO010000000
VERSION     DAVBBO010000117.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2066453
            Sequence Read Archive: ERR351777
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 311)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 311)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980402.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980402.1
            Genome Coverage       :: 176x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:17:33
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,141
            CDSs (total)                      :: 2,104
            Genes (coding)                    :: 1,953
            CDSs (with protein)               :: 1,953
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 16S)
            partial rRNAs                     :: 1 (23S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 151
            CDSs (without protein)            :: 151
            Pseudo Genes (ambiguous residues) :: 0 of 151
            Pseudo Genes (frameshifted)       :: 73 of 151
            Pseudo Genes (incomplete)         :: 76 of 151
            Pseudo Genes (internal stop)      :: 40 of 151
            Pseudo Genes (multiple problems)  :: 32 of 151
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..311
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2066453-rid20184263.denovo.117"
                     /strain="ST1"
                     /db_xref="taxon:1313"
     gene            complement(<1..>311)
                     /locus_tag="VQU30_002138"
     CDS             complement(<1..>311)
                     /locus_tag="VQU30_002138"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2448151.1"
                     /translation="ALVLAEADALVDAEAEALVDAEAEALVDADSEADVLAEADALVD
                     ADSDALVDAEAEALVDADAEALVLAEADALVLAEAEALVDAEAEALVLAEADALVEAE
                     A"
BASE COUNT           77 a           99 c           71 g           64 t
ORIGIN      
        1 tcagcttcgg cctcaacaag tgcgtcagct tcagcaagca ccagtgcttc ggcttcagcg
       61 tcgacaagtg cctcagcttc agcaagtacc agtgcgtcag cctcagcaag tactagcgcc
      121 tcagcatcag cgtcaacaag tgcttcggct tcagcgtcaa cgagtgcgtc tgagtcagca
      181 tcaacgagtg cgtcagcctc agcaagcaca tcagcttctg aatccgcatc aacaagtgct
      241 tcagcctcag cgtcaacaag tgcttcagct tcagcatcaa ccagtgcatc agcttcagca
      301 agtactagcg c
//
LOCUS       DAVBBO010000118          288 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ST1
            SAMEA2066453-rid20184263.denovo.118, whole genome shotgun sequence.
ACCESSION   DAVBBO010000118 DAVBBO010000000
VERSION     DAVBBO010000118.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2066453
            Sequence Read Archive: ERR351777
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 288)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 288)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980402.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980402.1
            Genome Coverage       :: 176x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:17:33
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,141
            CDSs (total)                      :: 2,104
            Genes (coding)                    :: 1,953
            CDSs (with protein)               :: 1,953
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 16S)
            partial rRNAs                     :: 1 (23S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 151
            CDSs (without protein)            :: 151
            Pseudo Genes (ambiguous residues) :: 0 of 151
            Pseudo Genes (frameshifted)       :: 73 of 151
            Pseudo Genes (incomplete)         :: 76 of 151
            Pseudo Genes (internal stop)      :: 40 of 151
            Pseudo Genes (multiple problems)  :: 32 of 151
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..288
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2066453-rid20184263.denovo.118"
                     /strain="ST1"
                     /db_xref="taxon:1313"
     gene            <1..>288
                     /locus_tag="VQU30_002139"
     CDS             <1..>288
                     /locus_tag="VQU30_002139"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000700388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="histidine motif-containing protein"
                     /protein_id="HET2448152.1"
                     /translation="NRVKAAKKVPLDRMPYNLQYTVEVKNGSLIIPHYDHYHNIKFEW
                     FDEGLYEAPKGYTLEDLLATVKYYVEHPNERPHSDNGFGNASDHVQRNKNG"
BASE COUNT           93 a           59 c           59 g           77 t
ORIGIN      
        1 caaccgcgtg aaagcagcta agaaggtgcc acttgatcgt atgccttaca atcttcaata
       61 tactgtagaa gtcaaaaacg gtagtttaat catacctcat tatgaccatt accataacat
      121 caaatttgag tggtttgacg aaggccttta tgaggcacct aaggggtata ctcttgagga
      181 tcttttggcg actgtcaagt actatgtcga acatccaaac gaacgtccgc attcagataa
      241 tggttttggt aacgctagcg accatgttca aagaaacaaa aatggtca
//
LOCUS       DAVBBO010000119          277 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ST1
            SAMEA2066453-rid20184263.denovo.119, whole genome shotgun sequence.
ACCESSION   DAVBBO010000119 DAVBBO010000000
VERSION     DAVBBO010000119.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2066453
            Sequence Read Archive: ERR351777
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 277)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 277)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980402.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980402.1
            Genome Coverage       :: 176x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:17:33
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,141
            CDSs (total)                      :: 2,104
            Genes (coding)                    :: 1,953
            CDSs (with protein)               :: 1,953
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 16S)
            partial rRNAs                     :: 1 (23S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 151
            CDSs (without protein)            :: 151
            Pseudo Genes (ambiguous residues) :: 0 of 151
            Pseudo Genes (frameshifted)       :: 73 of 151
            Pseudo Genes (incomplete)         :: 76 of 151
            Pseudo Genes (internal stop)      :: 40 of 151
            Pseudo Genes (multiple problems)  :: 32 of 151
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..277
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2066453-rid20184263.denovo.119"
                     /strain="ST1"
                     /db_xref="taxon:1313"
     gene            <1..>277
                     /locus_tag="VQU30_002140"
     CDS             <1..>277
                     /locus_tag="VQU30_002140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015511369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HET2448153.1"
                     /translation="QRIIEAIESALEKVDEYAESYNRLEQLDKEFPDKLKKSILQYAM
                     QGKLVEQDPNDESVEVLLEKIRAEKQKLFEEGKIKKKDLDISIVSQG"
BASE COUNT          126 a           37 c           47 g           67 t
ORIGIN      
        1 aacaacgcat aatagaagca atcgaatcag ctttagaaaa agtagatgaa tatgctgaaa
       61 gttataatag actagaacag ctagataaag aatttccaga taaactaaaa aaatctattc
      121 ttcaatatgc tatgcaagga aaattagttg aacaagaccc aaatgatgaa tcagtcgaag
      181 ttttacttga aaaaatacga gcagaaaaac aaaaactctt tgaagaaggc aagattaaaa
      241 agaaagattt ggacatttct attgtttccc aaggaga
//
LOCUS       DAVBBO010000120          229 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ST1
            SAMEA2066453-rid20184263.denovo.120, whole genome shotgun sequence.
ACCESSION   DAVBBO010000120 DAVBBO010000000
VERSION     DAVBBO010000120.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2066453
            Sequence Read Archive: ERR351777
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 229)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 229)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980402.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980402.1
            Genome Coverage       :: 176x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:17:33
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,141
            CDSs (total)                      :: 2,104
            Genes (coding)                    :: 1,953
            CDSs (with protein)               :: 1,953
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 16S)
            partial rRNAs                     :: 1 (23S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 151
            CDSs (without protein)            :: 151
            Pseudo Genes (ambiguous residues) :: 0 of 151
            Pseudo Genes (frameshifted)       :: 73 of 151
            Pseudo Genes (incomplete)         :: 76 of 151
            Pseudo Genes (internal stop)      :: 40 of 151
            Pseudo Genes (multiple problems)  :: 32 of 151
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..229
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2066453-rid20184263.denovo.120"
                     /strain="ST1"
                     /db_xref="taxon:1313"
     gene            <1..>229
                     /locus_tag="VQU30_002141"
     CDS             <1..>229
                     /locus_tag="VQU30_002141"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000700331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pneumococcal-type histidine triad protein"
                     /protein_id="HET2448154.1"
                     /translation="YTDDEIQVAKLAGKYTTEDGYIFDPRDITSDEGDAYVTPHMTHS
                     HWIKKDSLSEAERAAAQAYAKEKGLTPPSTDH"
BASE COUNT           72 a           49 c           55 g           53 t
ORIGIN      
        1 tacactgatg atgagattca agtagccaag ttggcaggca agtacacaac agaagacggt
       61 tatatctttg atcctcgtga tataaccagt gatgaggggg atgcctatgt aactccacat
      121 atgacccata gccactggat taaaaaagat agtttgtctg aagctgagag agcggcagcc
      181 caggcttatg ctaaagagaa aggtttgacc cctccttcga cagaccatc
//
